Datasets:

morteza

/

cogtext

like 0

10.1080/00028899908984438

American Industrial Hygiene Association journal

Am Ind Hyg Assoc J

Cognitive performance and mood during respirator wear and exercise.

The combined effects of respirator wear and low-intensity work on decision making and mood were assessed in eight subjects during 60 min of low-intensity treadmill walking with and without a respirator to determine whether the stresses of respirator wear negatively impact decision making. Subjects completed walks during no mask wear, wear of a respirator with high inspiratory resistance, and wear of a respirator with low resistance. Cognitive tasks included choice reaction (CHO), serial addition/subtraction (ADD), logical reasoning (LOG), and serial reaction (SER). Mood was measured using a questionnaire with 36 adjectives representing the factors of activity, anger, depression, fear, happiness, and fatigue. Data were obtained preexercise, after 20 and 40 min of walking, and postexercise. Combined respirator wear and low-intensity exercise did not affect accuracy, speed, or throughout in any of the cognitive tasks. Likewise, no significant effects of condition on the six mood factor scores were observed. These results show that the combination of respirator wear and low-level activity does not adversely alter cognitive performance or mood.

CognitiveConstruct

LogicalReasoning

10.1007/s002130050781

Psychopharmacology

Psychopharmacology (Berl)

Lack of an effect of zolmitriptan (Zomig, 311C90) on psychometric task performance: results of a placebo-controlled study in healthy volunteers.

The novel selective 5-hydroxytryptamine (5-HT)1B/1D agonist, zolmitriptan (Zomig, formerly known as 311C90), has shown good efficacy in the acute oral treatment of migraine. Zolmitriptan acts both centrally and peripherally, therefore it is important to assess central nervous system effects. At single doses of 25-50 mg (up to 8 times the likely therapeutic dose), zolmitriptan can cause sedation; therefore, a study was designed to examine the dose-response. A double-blind, randomized, placebo-controlled, six-limb crossover study in 13 healthy volunteers compared the effects of single oral doses of zolmitriptan (5, 10, 15 or 20 mg) and lorazepam (2 mg) on various psychometric tests. Zolmitriptan doses less than 20 mg had no statistically significant effects on choice reaction time, the Stroop test, visual analog scale (VAS) assessments of physical sedation, tranquilization and other types of feelings, the logical reasoning test or the adaptive tracking test. There was a mild transient increase in the subjective assessment on VAS of mental sedation which was dose related and occurred mainly with the highest zolmitriptan dose and were not reflected in objective measures of drug effects. In contrast, lorazepam (used as a positive control) was associated with statistically significant impairment in all tests (except tranquilization) for up to 10 h after dosing. The results demonstrate that therapeutic doses of zolmitriptan are unlikely to cause clinically significant impairment in psychometric performance.

CognitiveConstruct

LogicalReasoning

10.1162/089892998562744

Journal of cognitive neuroscience

J Cogn Neurosci

Neuroanatomical correlates of human reasoning.

One of the important questions cognitive theories of reasoning must address is whether logical reasoning is inherently sentential or spatial. A sentential model would exploit nonspatial (linguistic) properties of representations whereas a spatial model would exploit spatial properties of representations. In general terms, the linguistic hypothesis predicts that the language processing regions underwrite human reasoning processes, and the spatial hypothesis suggests that the neural structures for perception and motor control contribute the basic representational building blocks used for high-level logical and linguistic reasoning. We carried out a [(15)O] H(2)O PET imaging study to address this issue. Twelve normal volunteers performed three types of deductive reasoning tasks (categorical syllogisms, three-term spatial relational items, and three-term nonspatial relational items) while their regional cerebral blood flow pattern was recorded using [(15)O] H(2)O PET imaging. In the control condition subjects semantically comprehended sets of three sentences. In the deductive reasoning conditions subjects determined whether the third sentence was entailed by the first two sentences. The areas of activation in each reasoning condition were confined to the left hemisphere and were similar to each other and to activation reported in previous studies. They included the left inferior frontal gyrus (Brodmann area 45, 47), a portion of the left middle frontal gyrus (Brodmann area 46), the left middle temporal gyrus (Brodmann areas 21, 22), a region of the left lateral inferior temporal gyrus and superior temporal gyrus (Brodmann areas 22, 37), and a portion of the left cingulate gyrus (Brodmann areas 32, 24). There was no significant right-hemisphere or parietal activation. These results are consistent with previous neuroimaging studies and raise questions about the level of involvement of classic spatial regions in reasoning about linguistically presented spatial relations.

CognitiveConstruct

LogicalReasoning

Rinsho byori. The Japanese journal of clinical pathology

Rinsho Byori

[Consultation service for efficacious usage of laboratory tests based on logical reasoning and evidence].

To effectively respond to the desire for consultation in clinical practice, we must prepare logical reasoning and evidence which rationally supports laboratory test selection, the interpretation of test results and recommendation of certain tests to physicians. Standard of medical decision making can be used for logic issues such as posttest probability, test characteristics and receiver operating characteristics (ROC) curves and establishing appropriate cut-off points. Although we usually obtain evidence by consulting authorities or the literature, good evidence can also be obtained from meta-analysis. In addition, we can demonstrate the relationship of laboratory tests among several frequently occurring diseases and epidemiological tendencies such as frequency of causative organisms at several infection sites and bacterial sensitivities to antimicrobial agents, because we have access to a large-scale laboratory database. To construct a well-organized knowledge base with explicit evidence, cooperation among many facilities is necessary to develop system, which allows the free exchange of data.

CognitiveConstruct

LogicalReasoning

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Pac Symp Biocomput

DBGET/LinkDB: an integrated database retrieval system.

The integrated database retrieval system DBGET/LinkDB is the backbone of the Japanese GenomeNet service. DBGET is used to search and extract entries from a wide range of molecular biology databases, while LinkDB is used to search and compute links between entries in different databases. DBGET/LinkDB is designed to be a network distributed database system with an open architecture, which is suitable for incorporating local databases or establishing a specialized server environment. It also has an advantage of simple architecture allowing rapid daily updates of all the major databases. The WWW version of DBGET/LinkDB at GenomeNet is integrated with other search tools, such as BLAST, FASTA and MOTIF, and with local helper applications, such as RasMol. In addition to factual links between database entries, LinkDB is being extended to included similarity links and biological links toward computerization of logical reasoning processes.

CognitiveConstruct

LogicalReasoning

10.1016/s0891-5849(97)00432-2

Free radical biology & medicine

Free Radic Biol Med

Systemic oxidative stress and cognitive performance in the population-based EVA study. Etude du Vieillissement Artériel.

The aim of this study was to examine the relationships between cognitive functioning and blood levels of antioxidants and lipoperoxidation products in an elderly population. In 1991-1992, 1389 volunteers (574 men and 815 women aged 59 to 71 years) were recruited from the general population. Levels of selenium, carotenoids, and thiobarbituric-reactive substances in plasma and of vitamin E, glutathione peroxidase, and Cu-Zn superoxide dismutase in red blood cells were measured. Cognitive functioning was assessed with various psychometric tests. We used logistic regression to estimate the risk of poor cognitive functioning (< 25th percentile of the score distribution) associated with low values of each antioxidants (< 25th percentile) including potential confounding factors. A low level of total carotenoids (< 1.86 mumol/l) was associated with poor cognitive performance in two tests assessing visual attention and logical reasoning: the Trail-Making Test part B [OR = 1.34 IC95% (0.99-1.81), p = .055] and the Digit Symbol Substitution from the WAIS-R [OR = 1.38 IC95% (1.02-1.89), p = .04]. Low levels of other antioxidants and high levels of thiobarbituric-reactive substances were not related to poor cognitive functioning. Results observed with plasma carotenoids are in accordance with previous data obtained mostly from dietary records.

CognitiveConstruct

LogicalReasoning

10.1080/713755761

The Quarterly journal of experimental psychology. A, Human experimental psychology

Q J Exp Psychol A

Increases in intrusion errors and working memory deficit of poor comprehenders.

This study tests the hypothesis that the ability to inhibit already processed and actually irrelevant information could influence performance in the listening span test (Daneman & Carpenter, 1980) and have a crucial role in reading comprehension. In two experiments, the listening span test and a new working memory test were given to two groups of young adults, poor and good comprehenders, matched for logical reasoning ability. In Experiment 1, the poor comprehenders had a significantly lower performance in the listening span test associated to a higher number of intrusions--that is, recalled words that, in spite of being in sentence form, were not placed in the last position. In Experiment 2, a new working memory test was devised in order to analyse more effectively the occurrence of intrusions. Subjects were required to listen to a growing series of strings of animal and non-animal words. While listening, they had to detect when an animal word occurred, and at the end of each series they had to recall the last word of each string. The poor comprehenders obtained a significantly lower performance in the memory task and made a higher number of intrusions, particularly of animal words.

CognitiveConstruct

LogicalReasoning

Revue d'epidemiologie et de sante publique

Rev Epidemiol Sante Publique

[Longitudinal study of cognitive aging in non-demented elderly subjects].

The aim of this study is to describe and compare the course of the score of two psychometric tests during a five-year period in a cohort of non-demented elderly subjects. We studied a timed test of simple logical reasoning (the Digit Symbol Substitution Test of Wechsler) and a test of short-term visual memory (the Benton Visual Retention Test). Then we compared the course of these two tests with the course of the Mini-Mental State Examination (MMSE) which evaluates the general cognitive functioning and which has been studied previously. The sample consisted of 2792 subjects aged 65 years and older living at home at the beginning of the study (the Paquid cohort in Gironde). Subjects were interviewed at home by a psychologist at the baseline visit and one year, 3 years and 5 years after the baseline visit. All subjects who were diagnosed as demented at any of the four examinations were excluded from this study (218 subjects). The statistical analysis was performed using a mixed effects linear model and an additional analysis was performed to study sensitivity of the results to hypotheses regarding missing data mechanism. Among the three tests studied, only the score of the Digit Symbol Substitution Test declined over the five years (by -1.15 points for subjects aged 65 years to -3.4 points for subjects aged 85 years). We observed an improvement of the score between the first two visits which is sharper for the test of Benton and the MMSE than for the Digit Symbol Substitution Test and which reflects a stress effect at the baseline visit or a learning effect at the second visit. The difference between the cross-sectional measure of age effect and the longitudinal measure of time effect suggests either a cohort effect or a practice effect which would persist during the five years. The cognitive change in a non-demented elderly population is different according to the psychometric test used. Among the three tests studied, only the score of the Digit Symbol Substitution Test which has a a speed component declined over the five years.

CognitiveConstruct

LogicalReasoning

10.1016/s8755-7223(97)80082-8

Journal of professional nursing : official journal of the American Association of Colleges of Nursing

J Prof Nurs

Cognitive pathways and historical research.

The nursing literature is replete with articles detailing the logical reasoning processes required by the individual scientist to implement the rigors of research and theory development. Much less attention has been focused on creative and critical thinking as modes for deriving explanations, inferences, and conclusions essential to science as a product. Historical research, as a particular kind of qualitative research, is dependent on and compatible with such mental strategies as logical, creative, and critical thinking. These strategies depict an intellectual framework for the scientist examining archival data and offer a structure for such inquiry. A model for analyzing historical data delineating the cognitive pathways of logical reasoning, creative processing, and critical thinking is proposed.

CognitiveConstruct

LogicalReasoning

10.1002/(sici)1099-1166(199709)12:9<892::aid-gps657>3.0.co;2-0

International journal of geriatric psychiatry

Int J Geriatr Psychiatry

A cognitive neuropsychological approach to the study of delusions in late-onset schizophrenia.

Hypotheses to explain delusion formation include distorted perceptual processing of meaningful stimuli (e.g. faces), abnormal reasoning, or a combination of both. The study investigated these hypotheses using standardized neuropsychological tests. A three-patient case-study, compared with a small group (n = 8) of age-matched normal control subjects. Hospital in- and outpatients. Age-matched normal controls were from local residential homes. Three subjects with late-onset schizophrenia, two currently deluded and one in remission. Both deluded subjects had persecutory beliefs. One had a delusion of misidentification. All subjects were administered standardized neuropsychological tests of facial processing and tests of verbal reasoning. The test scores of the three patients were compared with published normal values and the age-matched control data. The tests demonstrated impaired matching of unfamiliar faces in deluded subjects, particularly in the subject with delusional misidentification. Increasing the emotional content of logical reasoning problems had a significant effect on the deluded subjects' reasoning but not that of the normal controls. The findings suggest impaired visual processing plus abnormal reasoning in deluded subjects. However, these impairments are relatively subtle given the severity of psychiatric disorder in the patients studied.

CognitiveConstruct

LogicalReasoning

10.1093/sleep/20.6.399

Sleep

Sleep

Speed of mental processing in the middle of the night.

This study aimed to determine whether human mental processing actually slows down during the night hours, separately from the previously documented microsleeps, lapses in attention, and general slowing of motor responses. Eighteen healthy young adults were studied during 36 hours of constant wakeful bedrest. Every 2 hours, they performed a logical reasoning task. Items phrased in the negative voice took reliably longer to respond to than items phrased in the positive voice, indicating the need for more mental processing in those items. By subtracting "negative" from "positive" reaction times at each time of day, we were able to plot a circadian rhythm in the time taken for this extra mental processing to be done separately from microsleeps, psychomotor slowing, and inattention. The extra mental processing took longer at night and on the day following sleep loss than it did during the day before the sleep loss, suggesting that human mental processing slows down during the night under sleep deprivation.

CognitiveConstruct

LogicalReasoning

10.1016/s0166-4328(97)81109-6

Behavioural brain research

Behav Brain Res

Problem solving and logical reasoning in the macaque monkey.

This study focuses on the performances of monkeys in a spatial problem-solving task that involves working memory. Two monkeys had to find, by trial-and-error, the touching order of 2 or 3 targets in a set of 3 or 4 fixed spatial targets. When a solution was found and performed 6 times, the order was changed and the animal had to resume a new search within the same set of targets. Thus, in a training session, many searches (up to 60) could be initialised. The data show that the animals conducted a methodical search for the hidden order and found the solution in a minimal number of trials. We conclude that the monkey is able to construct complex cognitive structures, similar to logical reasoning, to solve spatial problems of this type.

CognitiveConstruct

LogicalReasoning

10.1016/s0306-4530(96)00027-3

Psychoneuroendocrinology

Psychoneuroendocrinology

Does melatonin have an effect on cognitive performance?

Exogeneous melatonin causes phase shifts of circadian rhythms, reduces core body temperature, and induces drowsiness, but dispute still surrounds the hormone's effect on cognitive performance. Using a N = 1 double-blind alternating treatments design, daytime performance on four cognitive tests (logical reasoning, serial add/subtract, visual-spatial, and four-choice reaction time tasks) was measured after PO doses of placebo and 1.6 mg melatonin. Serum melatonin and core body temperature were also recorded. Performance was measured during time windows corresponding to the serum melatonin peak and the temperature trough respectively, following melatonin administration. The data showed that performance speed and accuracy measures were not affected during the serum melatonin peak, but that reaction times on all cognitive tasks increased substantially during the temperature trough. These results suggest that circulating melatonin has no direct and immediate effect on cortical information processing, and that the reduction in cognitive processing speed during body temperature trough occurs as a consequence of the hormone's hypothermic properties, causing a slowing down of cerebral processing speed.

CognitiveConstruct

LogicalReasoning

10.1016/0304-3940(96)13059-7

Neuroscience letters

Neurosci Lett

Early effect of ApoE-epsilon 4 allele on cognitive results in a group of highly performing subjects: the EVA study. Etude sur le Vieillissement Artériel.

We examined the association between apolipoprotein E (ApoE) epsilon 4 allele and cognitive performances in a population sample of 1174 high functioning volunteers aged 59-71 years. The neuropsychological battery included the Mini Mental State Examination (MMSE) and nine tests assessing visual attention, verbal memory, visual processing, logical reasoning, psychomotor rapidity, visual memory, auditory attention and verbal fluency. The ratio of genotypes with zero, one or two epsilon 4 alleles was 70.6%, 21.4% and 1.9%, respectively. The epsilon 4 allele was significantly associated with lower scores for visual attention, psychomotor rapidity and MMSE. In the best performer subgroup (MMSE score above 25, n = 1028), all relationships persisted. Our findings demonstrate that the ApoE-epsilon 4 allele is early associated with low normal cognitive performances in areas which are not specifically affected at the subclinical onset of dementia.

CognitiveConstruct

LogicalReasoning

10.1046/j.1365-2869.1996.t01-1-00001.x

Journal of sleep research

J Sleep Res

Enhanced performance in elderly subjects following bright light treatment of sleep maintenance insomnia.

Sixteen older individuals with sleep maintenance insomnia were treated with night-time bright-light exposure (BL) while living at home. Twelve consecutive days of acute light treatment were followed by a 3-mo maintenance light-treatment period. Subjects completed laboratory evaluation sessions on five separate occasions (prior to and following the acute light-treatment period, and once per month during the maintenance period). During each laboratory session, performance levels, sleep, and core body temperature were measured. The performance battery consisted of four computerized tasks (Logical Reasoning, Stroop Congruency, Two Letter Visual Search, and Wilkinson Four-Choice Reaction Time) and was administered every 2 h between 10.00 and 18.00 hours. Subjects improved significantly on three of the four tasks from pre-BL to post-BL. During the maintenance period, subjects who received active BL treatment maintained significantly higher performance levels than a control BL group. Light treatment improved sleep efficiency and delayed the phase of the body temperature rhythm. Performance improvements were significantly related only to sleep and not to circadian phase. The implications for non-circadian treatments of sleep maintenance insomnia and cognitive functioning in the elderly are discussed.

CognitiveConstruct

LogicalReasoning

10.1007/BF02805972

Psychopharmacology

Psychopharmacology (Berl)

Cognitive performance effects of subcutaneous nicotine in smokers and never-smokers.

In a double-blind placebo-controlled crossover study the effects of two doses of subcutaneous nicotine and saline were compared on a range of performance measures in 18 abstaining smokers and 18 never-smokers. Each subject received two injections (40 min apart) of saline, 0.3 mg nicotine, or 0.6 mg nicotine in a balanced order over three sessions. Performance was assessed before and after the injections on nine tests [news recall, Sternberg memory task, finger tapping, logical reasoning, rapid visual information processing (RVIP), long-term word recognition, digit recall, Stroop test, and critical flicker fusion threshold]. In the abstinent smokers, nicotine produced significantly faster correct responses on the logical reasoning test, more target hits, faster reaction times and improved sensitivity on the RVIP task, and more correct responses on word recognition. In never-smokers, nicotine produced faster reaction times on the RVIP and digit-recall tasks, although in the latter case this was at the expense of fewer correct responses. There were no significant differences between the two groups' responses to nicotine but smokers performed worse than never-smokers prior to injections, even controlling for background characteristics. These results are consistent with other recent research suggesting a primary effect of nicotine in enhancing cognitive performance.

CognitiveConstruct

LogicalReasoning

10.1212/wnl.47.2.444

Neurology

Neurology

Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease.

Inheritance of the apolipoprotein E (apoE) epsilon 4 allele is a risk factor for developing Alzheimer's disease (AD) and is associated with a lower age of dementia onset. The purpose of this study was to determine whether apoE genotypes differentially influence the course of cognitive decline in AD dementia. We administered nine cognitive tests that assessed explicit memory, attention, language, visuospatial function, frontal-lobe function, and logical reasoning abilities to 66 probable AD patients every 6 to 24 months over a span of up to 5.5 years. We identified apoE genotype by a PCR-based method; there were 16 patients with epsilon 3/3, 34 with epsilon 3/4, and 16 with epsilon 4/4. Using regression statistical methods, we computed the change in performance for each test for each patient over time. We then analyzed the mean change in each test in patients grouped according to apoE genotype. For the AD patients as a group, performance on all cognitive tests declined significantly over time, but the rate of decline did not vary significantly across apoE genotypes on any cognitive test. Specifically, the rate of cognitive decline was not faster in patients with an epsilon 4 allele than in those with epsilon 3/3. These results indicate that the mechanism placing individuals with an epsilon 4 allele at risk for developing AD does not influence the rate of cognitive decline. These observations imply that the influence of apoE epsilon 4 either precedes or occurs at an early point in the AD disease process.

CognitiveConstruct

LogicalReasoning

10.1007/BF02246647

Psychopharmacology

Psychopharmacology (Berl)

The effects of a benzodiazepine receptor antagonist beta-carboline ZK-93426 on scopolamine-induced impairment on attention, memory and psychomotor skills.

The effects of a single dose of scopolamine alone and in combination with ZK 93426 (a beta-carboline antagonist at the GABAA/BZ receptor complex with weak inverse agonist activity) were tested in two studies. In one study (study 1) the emphasis of enquiry was on different stages of information processing measured by a psychometric battery; in the second study (study 2) performance at different stages of memory and psychomotor abilities was tested and electroencephalogram recordings and video-tracking were also performed. Each study consisted of two parts, part I in which scopolamine (0.5 mg; 1 ml) or placebo were administered subcutaneously, and part II in which scopolamine (0.5 mg; 1 ml) was administered subcutaneously followed by an intravenous injection of ZK 93426 (0.04 mg; 0.04 ml/kg) or placebo. Thirty-six volunteers, who were randomly allocated to receive one of the two treatments (n = 18 per treatment), participated in each part. In study 1 attention was measured by a continuous attention task and a rapid information processing task, vigilance was measured by a visual vigilance task, and working memory and reasoning were evaluated by a logical reasoning task. A visual memory task was also included to measure acquisition and retention. In study 2 acquisition and short term storage and retrieval were measured by a word lists-Buschke restricted reminding procedure, and retention was tested by delayed recall and recognition. Psychomotor performance was assessed by measuring tapping speed (related to gross motoric abilities) and a pegboard task (related to fine motoric abilities). A task to measure working memory, the Pauli test, was also included. In study 1 scopolamine significantly impaired performance in the attentional and vigilance tasks (P < 0.05), but there was no effect in the logical reasoning task main measurements of time and accuracy. In study 2, scopolamine also impaired performance in the psychomotor tasks (P < 0.05) and the Pauli test. ZK 93426 partially antagonised most of the effects of scopolamine on memory and attention, suggesting that an interaction between the GABA-ergic and cholinergic systems is reflected in measurements of both attention and memory. In general a dissociation was found in the effects of scopolamine on memory, i.e. scopolamine impaired performance during all acquisition measurements but left retention unaffected.

CognitiveConstruct

LogicalReasoning

Aviation, space, and environmental medicine

Aviat Space Environ Med

Effects of daytime administration of zolpidem and triazolam on performance.

BACKGROUND AND HYPOTHESES: The performance-impairing effects of the short-acting imidazopyridine zolpidem (Ambien) were compared to those of triazolam (Halcion) following daytime administration. There were 70 male subjects who received oral zolpidem (5, 10 or 15 mg), triazolam (0.125, 0.25 or 0.5 mg), or placebo at 1000 hours. Performance on Logical Reasoning, Column Addition, and Repeated Acquisition (computerized tasks of the Walter Reed Performance Assessment Battery) was assessed prior to drug administration, then at 1.5 h (estimated time of peak drug effects) and 6 h post-administration. Number of trials completed (TC) and response time (RT) for correct answers on the Logical Reasoning (LR) and Column Addition (CA) tasks (expressed as percentage of pre-drug performance) were impaired by triazolam 0.5 mg (TC = 76.6 and 67.4% for LR and CA; RT = 182.1 and 127.0% for LR, CA) and zolpidem 15 mg (TC = 87.0 and 75.8% for LR, CA; RT = 198.7 and 161.8% for LR, CA) at 1.5 h post-administration. By 6 h post-administration, drug effects on performance had dissipated. Other doses of triazolam and zolpidem failed to impair performance significantly. These results indicate substantial performance impairment at estimated peak plasma concentrations of both triazolam and zolpidem, at or near doses coinciding with somnogenic efficacy. Thus, the present results suggest no advantage of benzodiazepine receptor-subtype-specific drugs (e.g., zolpidem). Rather, these results suggest that the performance-impairing effects of both drugs are dose-dependent and functionally coupled to their sleep-inducing properties.

CognitiveConstruct

LogicalReasoning

10.1111/j.1365-2869.1995.tb00172.x

Journal of sleep research

J Sleep Res

Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work. I. Effects on mood, fatigue, cognitive performance and body temperature.

Modafinil is an alerting substance that is considered safer than amphetamine with fewer side effects. Although modafinil has been used successfully to treat narcolepsy, relatively little is known about its ability to ameliorate fatigue and declines in mental performance due to sleep deprivation (SD) in a normal population. Forty-one military subjects received either 300 mg of modafinil, 20 mg of d-amphetamine, or placebo on 3 separate occasions during 64 hours of continuous cognitive work and sleep loss. Three drug treatments were given: at 23.30 hours and 05.30 hours during the first and second SD nights, respectively, and once at 15.30 hours during the third day of continuous work. Subjective estimates of mood, fatigue and sleepiness, as well as objective measures of reaction time, logical reasoning and short-term memory clearly showed better performance with both modafinil and amphetamine relative to placebo. Both modafinil and amphetamine maintained or increased body temperature compared to the natural circadian cycle observed in the placebo group. Also, from subject debriefs at the end of the study, modafinil elicited fewer side-effects than amphetamine, although more than the placebo group. Modafinil appears to be a good alternative to amphetamine for counteracting the debilitating mood and cognitive effects of sleep loss during sustained operations.

CognitiveConstruct

LogicalReasoning

10.1002/elps.11501601223

Electrophoresis

Electrophoresis

Some reminiscences of the history of electrophoresis.

Dole's and Longsworth's solution of the whole set of moving boundary equations by using the dimensionless transference numbers is reviewed. Longsworth's teachings on the nature of transference numbers and his pondering over transference numbers of proteins led the author to inquire why transference numbers of ampholytes were never measured. Logical reasoning on this subject led to the invention of isoelectric focusing.

CognitiveConstruct

LogicalReasoning

Zhonghua hu li za zhi = Chinese journal of nursing

Zhonghua Hu Li Za Zhi

[Exploration of nursing diagnosis with a cognitive reasoning model].

One of the important topics in theoretic studies on nursing diagnosis, still a new concept in China, is to explore the logical reasoning process from collecting data to making diagnoses. This paper introduced an epistemological model which mentions every step in detail on how to make a nursing diagnosis. The model was built on the basis of analyzing the knowledge structure of nursing diagnosis and applying the methodology of cognitive psychology.

CognitiveConstruct

LogicalReasoning

10.1007/BF02246298

Psychopharmacology

Psychopharmacology (Berl)

Scopolamine and lorazepam exert different patterns of effects in a test battery assessing stages of information processing.

The effects of a single dose of scopolamine (0.5 mg) SC and of lorazepam (2.5 mg) PO were tested in two independent studies for their effects on performance in a psychometric battery which measured functions related to different stages of information processing. Attention and vigilance were measured by a continuous attention task and a vigilance task, respectively. Working memory and reasoning were evaluated by the rapid information processing and logical reasoning task; memory acquisition and storage were measured by pre- and post-drug immediate and delayed recall using visual material. The following pattern of effects was revealed; both scopolamine and lorazepam impaired performance in attentional and vigilance tasks as well as in the rapid information processing task significantly (P < 0.05) when compared with their own placebo; in the logical reasoning task lorazepam significantly prolonged the time required to solve a problem; scopolamine did not have any effect on this task. Scopolamine impaired performance in the immediate recall but left delayed recall unaffected; lorazepam impaired only delayed recall, immediate recall remaining unaffected. These data suggest that scopolamine at this dose impaired mostly attention and early stages of information processes; lorazepam at the dose tested impaired also the later acquisition and encoding aspects of memory.

CognitiveConstruct

LogicalReasoning

Minerva psichiatrica

Minerva Psichiatr

[Cognitive functioning in adolescent depression].

In childhood and adolescent depression, the interaction between cognitive and emotional disorders is particularly evident: intellectual dysfunctioning often accompanies and integrates the clinical symptomatology. The studies on cognitive functioning have focused their attention on basic cognitive abilities; relatively fewer studies have analyzed other dimensions, such as logical reasoning. Furthermore, most studies have compared depressed patients to normal controls; this methodology tends to obscure the specific effect depression may have on cognitive functioning. The aim of our study is to analyze whether specific patterns of cognitive organization underlie adolescent depressive disorders. Cognitive functioning was assessed both with psychometric tests (WISC-R) and Piagetian logical reasoning tasks (Longeot Logical Thought Scale). The performance of depressed adolescents was compared to that of neurotic patients without depressive symptomatology. To evaluate the course of cognitive organization in relation to depressive symptomatology, some of our patients were studied in follow-up. Thirty-eight adolescents admitted to our Institute participated in the study. The experimental group consisted of 24 depressed adolescents; sixteen subjects were classified as neurotic depressives, eight were diagnosed as depressive personality disorder. The control group consisted of 14 subjects diagnosed as neurotic without depression. At the WISC-R the performance of depressed and controls adolescents were compared in: Full Scale IQ, Verbal and Performance IQ, Verbal-Performance discrepancy; single subtest scores; Bannatyne's four categories. Statistical analyses did not yield any significant differences between groups for any of the WISC-R measures. At the Logical Thought Scale Full Scale scores of the experimental group were significantly lower than controls'.(ABSTRACT TRUNCATED AT 250 WORDS)

CognitiveConstruct

LogicalReasoning

Aviation, space, and environmental medicine

Aviat Space Environ Med

Performance during mild acute hypoxia.

The controversy regarding the effects of mild hypoxia on learning performance needs to be resolved, since this may be affecting flight operations and safety. This study examined the ability to learn new tasks at low altitudes. Naive subjects (n = 144) performed spatial orientation (Manikin), serial choice reaction time (SCRT) and logical reasoning (Baddeley) tasks at ground level and at altitudes of 1,524 m (5,000 ft), 2,438 m (8,000 ft), 3,048 m (10,000 ft), and 3,658 m (12,000 ft), at rest or during exercise (VO2 = 600 ml O2.min-1) in a hypobaric chamber. Each task was performed over four serial repetitions (blocks) and presented at ground level or one of the four test altitudes in a first session, and in the reverse order in a second session. Performance for the Manikin and SCRT tasks improved significantly (p < 0.0001) over the 4 blocks. No significant difference was found between the corresponding 4 blocks of the first session in resting and exercising subjects tested at ground level before altitude compared to altitude before ground level. In general, RT for the 3 tasks were faster in resting than in exercising subjects. These results indicate that the ability to learn new tasks is not impaired by mild hypoxia at altitudes of up to 3,658 m. We detected a biphasic response to altitude in LRT and SCRT performance, but not for Manikin performance.

CognitiveConstruct

LogicalReasoning

10.1016/0031-9384(94)90266-6

Physiology & behavior

Physiol Behav

Impact of naps and caffeine on extended nocturnal performance.

It was hypothesized that alertness and performance during an extended work period would be improved by an afternoon nap and the subsequent use of caffeine during the night. Twelve young adults received a 4-h afternoon nap and caffeine during the night during one session and four 1-h naps during the night in a second session. After an afternoon nap, subjects had increased objective and subjective alertness, increased oral temperature, and increased performance on complex tasks like logical reasoning and correct additions when compared to the condition that allowed four nighttime naps. It was concluded that the specific scheduling of a nap period in preparation for an all-night work shift where sleep would not be allowed could result in increased alertness and performance as well as a less conflicted work situation.

CognitiveConstruct

LogicalReasoning

10.1080/00140139408963714

Ergonomics

Ergonomics

The use of prophylactic naps and caffeine to maintain performance during a continuous operation.

After a normal baseline night of sleep and a morning of baseline test performance, 24 young adult male subjects returned to bed from 16:00-20:00 prior to a 24 h period of sleep loss. Twelve subjects received caffeine 200 mg at 01:30 and 07:30. Performance tests (correctly completed addition problems, vigilance sensitivity, and logical reasoning correct responses) all indicated maintenance of baseline performance levels in the caffeine group after administration of caffeine while performance declined in the placebo group. Similar results were found for the Multiple Sleep Latency Test and Oral Temperature, which both remained near baseline levels throughout the observation period in subjects receiving caffeine. The results indicated that the combination of a prophylactic nap and caffeine was more effective in maintaining nocturnal alertness and performance than was the nap alone. Of more interest was the fact that the group which was given the combination of nap and caffeine was able to maintain alertness and performance at very close to baseline levels throughout a 24 h period without sleep.

CognitiveConstruct

LogicalReasoning

10.1016/0031-9384(94)90094-9

Physiology & behavior

Physiol Behav

Effects of fat content, weight, and acceptability of the meal on postlunch changes in mood, performance, and cardiovascular function.

This study examined the effects of fat content and meal size on postlunch changes in mood, performance, and cardiovascular function. Forty-six subjects (20 males, 26 females) were tested before and after lunch. Subjects were assigned to one of the following lunch conditions: a) low fat (23 g), large meal (860 g); b) low fat (18 g), small meal (600 g); c) high fat (84 g), large meal (840 g); d) high fat (79 g), small meal (530 g). The results showed only small effects of fat composition and meal size, with no cardiovascular effects being observed and no evidence of fat content or the weight of the meal influencing performance of logical reasoning or cognitive vigilance tasks. A few effects of meal type were significant in the mood data, but given the large number of analyses conducted, these could represent chance effects. Results from two selective attention tasks showed that subjects given the high-fat meals responded more slowly but more accurately, which differs from the effects of carbohydrate, protein, and calorie content reported in earlier papers. Weight of the meal influenced the degree of distraction from near and far distractors and also the accuracy of responses to central and peripheral targets. However, both the effects of fat and meal size were modified by task parameters, and further research is required before firm conclusions can be drawn about the functional importance of the influences of nutrient content and meal size on performance. The high-fat and large meals were rated as more acceptable than the low-fat and small meals.(ABSTRACT TRUNCATED AT 250 WORDS)

CognitiveConstruct

LogicalReasoning

10.1006/appe.1994.1005

Appetite

Appetite

Effects of evening meals and caffeine on cognitive performance, mood and cardiovascular functioning.

An experiment was carried out to examine the effects of an evening meal and caffeine (3 mg/kg) on performance, mood and cardiovascular functioning. Subjects given a meal reported that they felt stronger, more proficient and more interested than subjects in the no-meal condition. They also performed a logical reasoning task more quickly than the no-meal group. However, no effects were found on sustained attention tasks or tasks involving recall or recognition of word lists. The effects of evening meals are, therefore, different from either those observed after lunch or breakfast. Caffeine improved alertness and performance on sustained attention tasks for the group as a whole. Interactions between caffeine conditions and levels of impulsivity of the subjects were also found in memory tasks.

CognitiveConstruct

LogicalReasoning

10.1006/appe.1994.1004

Appetite

Appetite

Effects of breakfast and caffeine on cognitive performance, mood and cardiovascular functioning.

Two experiments examined the effect of breakfast (1.89 MJ) and caffeine (4 mg/kg) on cognitive performance, mood and cardiovascular functioning. In the first experiment, breakfast had no effect on performance of sustained attention tasks, but it increased pulse rate and influenced mood. The mood effects after breakfast differed between a cooked breakfast and a cereal/toast breakfast. In contrast to the effects of breakfast, this relatively high dose of caffeine improved performance of the sustained attention tasks, increased blood pressure and increased mental alertness. In the second experiment, effects of a breakfast and caffeine on mood and cardiovascular functions confirmed the results of the first study. The breakfast improved performance on free recall and recognition memory tasks, had no effect on a semantic memory task and impaired the accuracy of performing a logical reasoning task. In contrast to this, caffeine improved performance on the semantic memory, logical reasoning, free recall and recognition memory tasks. Overall, these results show that breakfast can improve performance in some but not all cognitive tasks and that these changes are very different from those observed after lunch, and those produced by caffeine.

CognitiveConstruct

LogicalReasoning

10.1016/0031-9384(93)90310-c

Physiology & behavior

Physiol Behav

Effects of sleep deprivation, lunch, and personality on performance, mood, and cardiovascular function.

The present study examined the effects of sleep deprivation on performance, mood, and cardiovascular functioning in the late morning and early afternoon. The results showed that the sleep-deprived subjects felt less alert and detected fewer targets in a cognitive vigilance task. Selective impairments due to sleep deprivation were also observed in a logical reasoning task. There was little evidence to suggest that consumption of lunch altered these effects of sleep deprivation. However, individual differences in the effects of sleep deprivation were apparent, with trait anxiety being related to the changes in subjective alertness produced by sleep deprivation, and sleep-deprived extraverts showing greater performance impairments than the sleep-deprived introverts.

CognitiveConstruct

LogicalReasoning

10.1007/BF00209727

The Clinical investigator

Clin Investig

Behavioral aspects of human adaptation to space: analyses of cognitive and psychomotor performance in space during an 8-day space mission.

Living in the space environment and exposure to microgravity induce a number of effects that may interfere with human cognitive and psychomotor performance. However, up to now very few attempts have been made to monitor possible impairments of human performance during space missions. In the present single-case study several cognitive and psychomotor functions were monitored during an 8-day space mission to an orbital station using a computerized performance monitoring device. This device included four different tasks, which were selected from a battery of Standardized Tests for Research with Environmental Stressors published recently by the NATO Advisory Group for Aerospace Research and Development, and which demanded logical reasoning and decision-making functions, memory retrieval functions, and fine manual control. Each task was performed 23 times (6 preflight, 13 inflight, 4 postflight sessions). By means of single-subject statistics inflight performance was compared with baseline performance during pre- and postflight sessions. In accordance with the few previous performance studies conducted during space flights, speed and accuracy of short-term memory retrieval and logical reasoning functions remained unimpaired during the stay in space. However, clear decrements in tracking performance were found, showing to increased difficulties in fine manual control. These results suggest that performance decrements in space may arise primarily in psychomotor functions due to alterations requiring an effortful accommodation of motor skills which had been acquired under 1-g conditions to the new conditions of microgravity.

CognitiveConstruct

LogicalReasoning

10.1111/j.2044-8295.1993.tb02492.x

British journal of psychology (London, England : 1953)

Br J Psychol

Behavioural problems associated with the chronic fatigue syndrome.

Disturbances of memory, concentration and motor function are often reported by patients with the chronic fatigue syndrome (CFS). The present study objectively evaluated these behavioural problems using a computerized test battery measuring memory, attention and motor skills. Fifty-seven CFS patients were compared with 19 matched controls and all subjects completed the performance test battery and filled in questionnaires measuring psychopathology and mood. The patients reported significantly higher levels of depression, anxiety, physical symptoms and cognitive failures than the controls. Similarly, they reported more negative affect at the time of testing. The patients were slower on psychomotor tasks, showed increased visual sensitivity and impaired attention. Digit span and free recall were not impaired but retrieval from semantic memory and logical reasoning were slower. None of the performance differences between patients and controls could be attributed to differences in psychopathology. These results agree with recent findings from other laboratories, and it is now time to consider the nature of the neurological dysfunction underlying these effects.

CognitiveConstruct

LogicalReasoning

10.1016/0141-5425(93)90116-g

Journal of biomedical engineering

J Biomed Eng

AIDA2: a Mk. II automated insulin dosage advisor.

A prototype computer system has been developed to provide advice on the day-to-day adjustment of insulin dosage in the insulin-dependent (type 1) diabetic patient. The system also allows the patient's daily steady-state blood glucose profile to be generated based on these adjustments using a clinical model of glucose-insulin interaction. The prototype is intended to be used as a decision support system by clinical personnel. It is designed for use during consultations, as a simulator of patient response following changes in the insulin and/or dietary regimen, and as a system to provide education on planning insulin therapy. Advice is generated by a qualitative therapeutic advisor which suggests what the next step in improving glycaemic control might be for a given patient. The clinical model attempts to reflect the underlying (patho)physiology of insulin action and carbohydrate absorption in quantitative terms. It consists of a one-compartment glucose model linked to a model with plasma and 'active' insulin compartments. An overview of the integrated prototype is provided along with a detailed description of the new time-point-orientated logical reasoning methodology adopted by the therapeutic advisor. The operation of the system is illustrated by a clinical case study from a 70 kg, male, insulin-dependent diabetic patient.

CognitiveConstruct

LogicalReasoning

10.1080/07420529309059699

Chronobiology international

Chronobiol Int

Sleep inertia: best time not to wake up?

Sleep inertia is a brief period of inferior task performance and/or disorientation immediately after sudden awakening from sleep. Normally sleep inertia lasts < 5 min and has no serious impact on conducting routine jobs. This preliminary study examined whether there are best and worst times to wake up stemming from circadian effects on sleep inertia. Since the process of falling asleep is strongly influenced by circadian time, the reverse process of awakening could be similarly affected. A group of nine subjects stayed awake for a 64-h continuous work period, except for 20-min sleep periods (naps) every 6 h. Another group of 10 subjects stayed awake for 64 h without any sleep. The differences between these two groups in performance degradation are expected to show sleep inertia on the background of sleep deprivation. Sleep inertia was measured with Baddeley's logical reasoning task, which started within 1 min of awakening and lasted for 5 min. There appeared to be no specific circadian time when sleep inertia is either maximal or minimal. An extreme form of sleep inertia was observed, when the process of waking up during the period of the circadian body temperature trough became so traumatic that it created "sleep (nap) aversion." The findings lead to the conclusion that there are no advantages realized on sleep inertia by waking up from sleep at specific times of day.

CognitiveConstruct

LogicalReasoning

La Medicina del lavoro

Med Lav

[Occupational Raynaud's phenomenon in a dentist: a case report].

After more than 39 years of practice, a dentist showed Raynaud's phenomenon of the hand exposed to vibrations generated by dental instruments. Other possible occupational, pharmacological and systemic disease factors that could cause Raynaud's phenomenon were excluded. Since it has been reported in the literature that dentists and dental technicians could exceed the permissible limits for vibrations, an occupational etiology of this case is suggested on the basis of logical reasoning.

CognitiveConstruct

LogicalReasoning

10.1111/j.1365-2648.1992.tb01832.x

Journal of advanced nursing

J Adv Nurs

Diagnostic reasoning among second-year nursing students.

This paper reports on a study investigating the relationship of nursing students' approaches to learning and processing of information, science content knowledge, ability in interpreting and organizing clinical data (nursing assessment), and logical reasoning ability with the accuracy and quality of the nursing diagnosis made in a simulated diagnostic reasoning task. One hundred and sixty-nine second-year pre-service nursing students participated in the study. Results of path analyses indicated a set of pathways from surface approach to low-quality nursing diagnosis that reflected less competent diagnostic reasoning; and a second set from deep/achieving approach through content knowledge and logical reasoning to higher-quality nursing diagnosis that reflected more competent diagnostic reasoning. The implications of these findings for nurse education are discussed.

CognitiveConstruct

LogicalReasoning

10.1016/0094-5765(92)90189-p

Acta astronautica

Acta Astronaut

Results of the ESA study on psychological selection of astronaut applicants for Columbus Missions I: aptitude testing.

European participation in the Space Station Freedom brought about new challenges for the psychological selection of astronaut candidates, particularly in respect to specific demands of long duration space flights. For this reason existing selection criteria and methods were reassessed. On these grounds a study was undertaken applying a unique composition of aptitude tests to a group of 97 ESA scientists and engineers who are highly comparable to the expected astronaut applicants with respect to age and education. The tests assessed operational aptitudes such as logical reasoning, memory function, perception, spatial orientation, attention, psychomotor function, and multiple task capacity. The study goals were: 1) Verification of psychometric qualities and applicability of tests in a normative group; 2) Search for culture-fair tests by which multi-national groups can be examined; 3) Identification of test methods which consider general and special operational demands of long duration space flights. Based on the empirical findings a test battery was arranged for use in the selection of ESA astronaut applicants. Results showed that 16 out of the 18 employed tests have good psychometric qualities and differentiate reliably in the special group of testees. The meta structure of the test battery as described by a factorial analysis is presented. Applicability of tests was generally high. Tests were culture-fair, however, a relation between English language skills and test results was identified. Since most item material was language-free, this was explained with the importance of English language skills for the understanding of test instructions. Solutions to this effect are suggested.

CognitiveConstruct

LogicalReasoning

10.1177/026988119200600306

Journal of psychopharmacology (Oxford, England)

J Psychopharmacol

The effects and after effects of the α2-adrenoceptor antagonist idazoxan on mood, memory and attention in normal volunteers.

Idazoxan, an α( 2)-adrenoceptor antagonist, is an effective antidepressant with a mode of action different from that of conventional antidepressants. As it is used as an antidepressant it is important to know whether there are any unwanted CNS side effects. Study of its effects will also provide information on the relationship between noradrenergic function and mood and performance. Twelve normal male volunteers who were given the drug (40 mg orally three times daily for 21 days) were compared with 12 matched controls. A computerized test battery was used to assess mood and various aspects of memory and attention. Many of the tests of memory and attention in the battery have been widely used over the last 20 years, and in addition two new selective attention tasks were included. The subjects were tested 3 days before starting the drug, on days 3 and 17 while on the drug, and after they had stopped taking the drug (4 days after and 24 days after). Control subjects followed a similar testing schedule. The results showed that the drug had no effect on mood, logical reasoning, retrieval from semantic memory or sustained attention. However, the drug did improve one aspect of selective attention (the place repetition effect), although this effect was only observed on the third day on the drug. Overall, the results suggest that idazoxan produces selective performance improvements, and that the measures of selective attention used here may be more sensitive indicators of drug effects than some of the traditional tasks currently in use.

CognitiveConstruct

LogicalReasoning

10.1007/BF02244970

Psychopharmacology

Psychopharmacology (Berl)

Comparison of the daytime sleep and performance effects of zolpidem versus triazolam.

Fifty healthy male subjects were administered zolpidem (5, 10, or 20 mg), triazolam (0.5 mg) or placebo, then attempted to sleep in a non-sleep-conducive environment. Subjects were awakened at 90 min post-drug (near peak blood concentration for both drugs) and tested on several cognitive tasks, including Two Column Addition, Logical Reasoning, and a Simulated Escape Task. This was followed by a second, 3.5-h sleep period. Hypnotic efficacy of the 20 mg zolpidem (Z-20) dose was similar to that of the 0.5 mg triazolam (TRIAZ) dose, as indicated by comparably shortened sleep latencies and lengthened total sleep times. Though accuracy on most performance measures was not affected by either drug, a reduction in speed of responding on logical reasoning and addition tasks was evident for the TRIAZ group at 90 min post-drug (Ps less than 0.05). On the simulated escape task, only triazolam significantly increased the mean number of errors, and interfered with subsequent memory of the task. Thus, zolpidem had milder effects on performance than triazolam. However, 60% of the Z-20 subjects experienced mild, adverse physical reactions. Performance differences between somnogenically comparable doses of zolpidem and triazolam may be due to their differential affinities for the BZ1 and BZ2 receptor subtypes.

CognitiveConstruct

LogicalReasoning

History and philosophy of the life sciences

Hist Philos Life Sci

Koch's postulates and the etiology of AIDS: an historical perspective.

This paper examines the debate over the human immunodeficiency virus (HIV) as the cause of acquired immunodeficiency syndrome (AIDS) from an historical perspective. The changing criteria for proving the link between putative pathological agents and diseases are discussed, beginning with Robert Koch's research on anthrax in the late nineteenth century. Various versions of 'Koch's postulates' are analyzed in relation to the necessity and sufficiency arguments of logical reasoning. In addition, alterations to Koch's postulates are delineated, specifically those required by the discovery of rickettsiae and viruses in the early twentieth century and by the immunological testing developed after mid-century to demonstrate the links between elusive viral agents and two diseases, hepatitis B and infectious mononucleosis. From this perspective, an examination of the AIDS debate is constructed. Molecular biologist Peter Duesberg's argument that HIV is not the cause of AIDS is analyzed in light of his contention that a version of Koch's postulates has not been satisfied. Additional research findings through 1990 relating to the etiology of AIDS are also noted.

CognitiveConstruct

LogicalReasoning

10.1159/000118920

Neuropsychobiology

Neuropsychobiology

Effects of breakfast and caffeine on performance and mood in the late morning and after lunch.

The aim of the present study was to examine the effects of breakfast and caffeine on performance, mood and cardiovascular functioning in the late morning and after lunch. Forty-eight subjects were tested at 07.45 and subjects then assigned to one of the four conditions formed by combining caffeine and breakfast conditions. Subjects in the caffeine condition were given a dose of 4 mg/kg, the caffeine manipulation being double blind. At 11.15 subjects were given another coffee (subjects remained in the same caffeine condition) and had lunch at 12.30. Performance was examined prior to lunch (11.30) and after lunch (14.00). Effects of breakfast on recognition memory (lower false alarm rate) and logical reasoning (reduced accuracy) were found in the late morning but not after lunch. However, a semantic processing task was performed more slowly by the breakfast group after lunch. Caffeine improved performance on a sustained attention task, the logical reasoning task and semantic memory task. Subjects given caffeine also reported greater alertness and feelings of well-being, whereas the effects of breakfast on mood changed from the late morning to early afternoon. Few interactions between breakfast and caffeine conditions were obtained.

CognitiveConstruct

LogicalReasoning

10.1177/002221949102400603

Journal of learning disabilities

J Learn Disabil

The fundamental skills of higher order thinking.

It may be possible to teach reasoning strategies to subjects with poor reasoning, including many subjects with learning disabilities (LD), using curriculum designed around a sameness analysis. The higher order thinking skills of analogical and logical reasoning are defined using the sameness analysis methodology. The sameness in the strategy for forming a generalization from experience is called "reasoning by analogy," while the sameness in the strategy for applying generalizations is described by the syllogism (logical reasoning). The research base for effective instruction in analogical and logical reasoning, particularly with subjects with LD, is summarized. The wide applicability of reasoning by analogy and by syllogism as complementary strategies is illustrated through their use in a critical review of the editorial page of a daily newspaper, and in linking content material in several domains.

CognitiveConstruct

LogicalReasoning

10.1177/026988119100500205

Journal of psychopharmacology (Oxford, England)

J Psychopharmacol

The effects of caffeine, impulsivity and time of day on performance, mood and cardiovascular function.

Two experiments were carried out to examine the effects of caffeine on performance, mood and cardiovascular function. The results showed that the effects of caffeine depended on the dose, time of administration, the function being examined and the impulsivity of the subject. Changes in blood pressure were only observed when a high dose (3 mg/kg) was used. The effects of this dose on performance depended on the impulsivity of the subject, with high impulsives performing worse in the de-caffeinated condition but getting a greater benefit from the caffeine. The high dose of caffeine also removed the post-lunch dip in sustained attention. The second experiment, which used a lower dose of caffeine (~60 mg), failed to demonstrate any caffeine x impulsivity or caffeine x time of day effects on performance. However, caffeine improved performance on a logical reasoning task and caffeine x time of day x impulsivity effects were found in analyses of visual search tasks. The mood data also support the view that the effects of caffeine depend on a combination of factors similar to those outlined for performance.

CognitiveConstruct

LogicalReasoning

10.1159/000282240

Urologia internationalis

Urol Int

Trends in future urodynamics: computer support-data base-digitized imaging.

The use of computers in urodynamics must be based preferably on the structure of the urodynamic investigation itself. This enables implementation of computerized systems in the urodynamic laboratory in the most natural way and provides transparency of urodynamic software for the investigators. Additionally, the algorithms of the urodynamic software then can provide for a urodynamic investigation following a logical path based on the patient's history and clinical data and (automatically interpreted) results from earlier steps in the urodynamics. As an extension of this structured logical reasoning, the computer use in urodynamics can be extended to include validation and decision rules, comprising measurement data and rules for interpretation and combination of history, clinical and measurement data. Conclusions will be presented then in the form of a preliminary differential diagnosis, including the odds for each of the possible diagnoses. These kinds of computerized interpretation systems will be validated by comparison with the classical clinical diagnoses and are generally known as expert systems. These systems rely on logical branching-as opposed to systems that are statistical in nature and use large data bases to classify individual data into known groups. Data bases will remain for the purpose of documentation, based on individual patients and comprising all patient data-comparable to the existing patient files in the hospital's archives. The computer files have to include also the original data from functional studies like urodynamics-and not just the abstracted conclusions-and from imaging techniques. Intelligent compression of data prevents the data bases from exploding. Digital imaging techniques combined with computerized urodynamic investigations open possibilities for dynamic analysis of morphologic data and combination thereof with urodynamic measurement data.

CognitiveConstruct

LogicalReasoning

Adolescence

Adolescence

Sexual activity and contraceptive use among low-income urban black adolescent females.

A modified form of Nathanson and Becker's (1983) Health Belief Model Questionnaire and other measures designed to assess cognitive processing were administered to low-income black adolescent female clients of an inner-city comprehensive health care clinic. The purpose of the study was to explore determinants of sexual activity and contraceptive use. Subjects were classified as not sexually active (n = 50), sexually active/noncontracepting (n = 20), or sexually active/contracepting (n = 72). Not sexually active subjects tended to be younger, more career motivated, to have a father at home, to be more influenced by family values, and to have more conservative attitudes regarding adolescent sexuality than did sexually active subjects. Sexually active/noncontracepting subjects tended to report fewer benefits and more barriers to the use of contraception. Level of cognitive processing did not differ among the three groups, but was at a lower-than-expected level for age. Finally, inconsistent contraceptive use was common to both sexually active groups.

CognitiveConstruct

LogicalReasoning

10.1016/0892-0362(90)90080-v

Neurotoxicology and teratology

Neurotoxicol Teratol

Neurobehavioral effects of a long-term exposure to tetraalkyllead.

Employees of a factory producing antiknock additives for gasoline were examined psychologically after an exposure of an average of 14 years. A neurobehavioral symptom questionnaire, tests of single and choice reaction time, a cancellation task and a digit symbol test were the neurobehavioral variables. Total lead in urine and trimethyllead in urine showed different patterns of correlation with the neurobehavioral measures. Intellectual abilities (logical reasoning), age, and job years were controlled by partial correlation statistics as possible confounders. Referring to the low level of 21 micrograms lead per 100 ml blood and regarding the dose-response relations reported in the literature, the results support the hypothesis of a special neurotoxicity of the alkyllead compounds.

CognitiveConstruct

LogicalReasoning

10.1001/archneur.1990.00530080072013

Archives of neurology

Arch Neurol

Carbamazepine-10,11-epoxide in epilepsy. A pilot study.

The effects of carbamazepine-10,11-epoxide, an active metabolite of carbamazepine, were evaluated in seven outpatients with frequent epileptic seizures. The study included an initial 4-week period with the carbamazepine dose optimized for each patient. Patients were then crossed over, dose by dose, to carbamazepine-10,11-epoxide and followed up for another 4 weeks. Dosing was single blind. The evaluation of the anticonvulsant effect was hampered by marked fluctuations in plasma levels during treatment with carbamazepine-10,11-epoxide. There was, however, no significant change in seizure control. During epoxide treatment, no subjective side effects were reported despite epoxide plasma concentrations up to 57 mumol/L. Neuropsychological assessment revealed a significant improvement in finger motor speed and logical reasoning during the carbamazepine-10,11-epoxide period. Subnormal serum sodium levels in two patients were normalized after switching from carbamazepine to the epoxide. Continued investigations with this active metabolite of carbamazepine in epilepsy are therefore justified.

CognitiveConstruct

LogicalReasoning

Canadian journal of psychiatry. Revue canadienne de psychiatrie

Can J Psychiatry

[Formal thinking, logical-discursive operations and schizophrenia: experimental study of a clinical case].

This study, based on a single case experimental design, examined logical reasoning in a schizophrenic meeting the DSM-III criteria. The quantitative assessment carried out by 32 psychiatrists on a rating scale for logical thinking disorders (nine items, six points) of the retranscribed clinical interview showed 1. that the assessments varied in a statistically significant way according to items and psychiatrists, and that these variations were independent of their degree of experience--the correlations between the different items of the rating scale proved to be weak and not significantly different from zero; and 2. the study of the most contradictory statements carried out by a logician using reasoning analysis procedures concluded that there were in fact logical relationships between the subjects the schizophrenic talked about. The results are discussed in relation to the methodology of assessing formal thought in schizophrenia.

CognitiveConstruct

LogicalReasoning

10.1007/BF00867216

Psychological research

Psychol Res

The impact of cognitive interference on performance during prolonged sleep loss.

A study was conducted on the effects of off-task cognitions on performance during sleep deprivation. Subjects answered the Thought Occurrence Questionnaire, assessing their proneness to engage in off-task cognitions, and were deprived of sleep for 72 hours, during which they performed a variety of tasks including visual discrimination and three versions of a logical reasoning task in which cognitive load was varied systematically. In addition, every day subjects answered the Cognitive Interference Questionnaire, which taps off-task cognitions during the experiment. Results indicated that subjects who habitually engage in off-task cognitions performed worse during 72 hours of sleep loss than subjects who do not engage in such distracting activities. In addition, it was found that the engagement in off-task cognitions increased during the 72 hours of sleep loss and such an engagement was related to deficits in performance accuracy. The mechanisms of off-task cognitions and sleep loss underlying these effects are discussed.

CognitiveConstruct

LogicalReasoning

10.3109/07420529009056966

Chronobiology international

Chronobiol Int

Circadian variation in human performance evaluated by the Walter Reed performance assessment battery.

As part of a two clock-time (0830 versus 2030) evaluation of administration-time dependent effects of dexedrine (5 mg) and triazolam (0.25 mg) on human cognitive performance, placebo (control) studies were conducted on 12 diurnally active (0700-2300) male adults (23-38 yrs) using a double-blind, randomized crossover design. Testing was conducted hourly during a series of sleepless 13-hr spans commencing in the morning or evening, using the Walter Reed computer controlled and scored multi-task cognitive performance assessment battery. For the placebo condition, Single and Group Cosinor analyses documented circadian rhythms in performance for most tasks (reaction time, logical reasoning, serial add/subtract and spatial orientation) both for individuals and the group. Overall, performance was worse overnight, when sleepiness was greatest, and best between 1830 and 2030. It was most variable around 0600-0700. The day-night variation in performance over all cognitive tests amounted to 21% of the 24-hr mean.

CognitiveConstruct

LogicalReasoning

Medicine and law

Med Law

A legal perspective of the concept of life.

The problem of defining life is discussed, using as foundation Herman Dooyeweerd's philosophy of the Cosmonomic Idea, which holds that life is indefineable. Contemporary legal and philosophical writings concerning the exact moments of life and death are explored. While conceding the importance of these in the determination of the precise beginning and end of legal personhood, the author concludes that the concept of life is unfathomable.

CognitiveConstruct

LogicalReasoning

Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress

Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir

[Effects of intuition on determining indications and intraoperative procedure].

Intuition is used in medical decision-making, especially in a decision for surgery and in selection of the surgical procedure. Intuitive decisions are made without reasoning. They are often correct if the prerequisite experience and knowledge are available to the physician. Intuition is related to heuristic techniques and uses them (representativeness, availability, anchoring). Decisions made on the basis of intuition must be controlled by systematic and logical reasoning.

CognitiveConstruct

LogicalReasoning

10.1016/0091-3057(89)90316-x

Pharmacology, biochemistry, and behavior

Pharmacol Biochem Behav

Dose-dependent effects of atropine on behavioral and physiologic responses in humans.

Atropine is an antimuscarinic which has been frequently studied with learning and performance tasks using both human and animal subjects. However, interpretation of data from human studies is limited by the relatively narrow range of doses used in most such studies. In the present study a wide range of atropine doses (0, 1.5, 3.0, 6.0 mg/70 kg) were given, intramuscularly, to human volunteers to assess the effects of atropine on a variety of behavioral measures, subject ratings, and physiologic function. The time course of responses was examined over 24 hours. Behavioral measures were a computerized Performance Assessment Battery (PAB) which contained measures of logical reasoning, short-term memory and rapid arithmetic, a Digit Symbol Substitution Test (DSST), and a psychomotor test of hand-eye coordination (Circular Lights). Administration of atropine produced both time- and dose-dependent effects on most measures used, although sensitivity varied across measures. At the 1.5 mg dose, no effects on performance were detected, however, after 6.0 mg reliably and 3.0 mg occasionally, impairments occurred on measures of accuracy and speed of performance. These effects generally began by 1.5 hours postdrug and returned to baseline by 7-9 hours postdrug. In contrast, certain subject ratings and physiologic variables were affected by lower doses of atropine, showing deviations from baseline at 1.5 mg and producing a time course of effects that was both earlier in onset and longer in duration than was observed with the performance measures. The present results have practical implications for the clinical utilization of atropine in situations in which optimal performance is required.

CognitiveConstruct

LogicalReasoning

10.1080/00140138908966836

Ergonomics

Ergonomics

Oral temperature and performance in 8 h and 12 h shifts.

Operators in an 8 h (n = 18) and a 12 h (n = 16) h shift went through an experiment in which oral temperature, disjunctive reaction time (DRT), tapping, logical reasoning, memory and search tasks were measured at 4 h intervals. A performance curve in DRT and in tapping over a 24 h cycle tended to follow the pattern of the body temperature curve. The curves of mental curves were flattened. The values measured in the two groups of Ss revealed differences of statistical significance.

CognitiveConstruct

LogicalReasoning

10.1016/0002-9378(89)90222-6

American journal of obstetrics and gynecology

Am J Obstet Gynecol

Heuristic determination of relevant diagnostic procedures in a medical expert system for gynecology.

Many professions including medicine have standard operating procedures for the performance of their tasks. In the construction of expert systems, knowledge engineers have exploited this fact in devising heuristic rules that mimic the standard practice among such personnel (i.e., experts). This article suggests that the expert system designer should not stop at the level of the standard operating procedure heuristic but should instead investigate the reasons that the standard procedures have become standard. Because the experts in a field often do not understand the reasons for the standard operating procedures of their profession, this effort not only rewards the system designer but the expert as well. Because medical training does not always emphasize the logical reasoning underlying certain standard operating procedures, the ability to perform this reasoning is especially important in medicine. Further, a medical expert system for consultation or education would make a valuable impact by incorporating such knowledge and inference rules. This article investigates the development of a computerized medical expert system that applies the principles of artificial intelligence by limiting the number of questions and tests to find the solution for an ill-defined complex problem. Finally, we describe a logic program that tests the basic ideas.

CognitiveConstruct

LogicalReasoning

Versicherungsmedizin

Versicherungsmedizin

[Exertion, spinal fracture, intervertebral disk displacement].

If causes which cannot be clearly defined as traumatic, result in vertebral fractures or disc ruptures, the expert frequently finds himself confronted with considerable problems. He must carefully establish the relation between what is due to the trauma and what must be attributed to the pre-existing damage. This requires the pre-existing nox to be objectively cleared, especially with regard to osteoporosis. The diagnosis "osteoporosis" should be subjected to particularly careful investigation, especially if the patient is a male. X-ray photographs, taken at an early stage, are insufficient. As consequences for the patient might be heavy, intensive methods of examination are justified. Anamnesis, progress and effect must be critically weighted, exceptions from the rule must be founded on careful and logical reasoning. The above article deals with such an exception.

CognitiveConstruct

LogicalReasoning

10.1016/0010-0277(89)90023-1

Cognition

Cognition

The logic of social exchange: has natural selection shaped how humans reason? Studies with the Wason selection task.

In order to successfully engage in social exchange--cooperation between two or more individuals for mutual benefit--humans must be able to solve a number of complex computational problems, and do so with special efficiency. Following Marr (1982), Cosmides (1985) and Cosmides and Tooby (1989) used evolutionary principles to develop a computational theory of these adaptive problems. Specific hypotheses concerning the structure of the algorithms that govern how humans reason about social exchange were derived from this computational theory. This article presents a series of experiments designed to test these hypotheses, using the Wason selection task, a test of logical reasoning. Part I reports experiments testing social exchange theory against the availability theories of reasoning; Part II reports experiments testing it against Cheng and Holyoak's (1985) permission schema theory. The experimental design included eight critical tests designed to choose between social exchange theory and these other two families of theories; the results of all eight tests support social exchange theory. The hypothesis that the human mind includes cognitive processes specialized for reasoning about social exchange predicts the content effects found in these experiments, and parsimoniously explains those that have already been reported in the literature. The implications of this line of research for a modular view of human reasoning are discussed, as well as the utility of evolutionary biology in the development of computational theories.

CognitiveConstruct

LogicalReasoning

10.3109/14639238909010876

Medical informatics = Medecine et informatique

Med Inform (Lond)

A system for computer-aided diagnosis.

MEDICIS is an integrated environment for computer-aided diagnosis. It consists of two subsystems: a module used by the expert to build knowledge bases and a consultation module to exploit those bases. MEDICIS uses a framed representation of knowledge. The inference engine performs logical reasoning without recourse to certainty factors. This phase is followed by a multicriteria analysis.

CognitiveConstruct

LogicalReasoning

10.1007/BF00589903

Psychopharmacology

Psychopharmacology (Berl)

Administration of triazolam prior to recovery sleep: effects on sleep architecture, subsequent alertness and performance.

The effects of triazolam (0.125, 0.25, and 0.5 mg) versus placebo on recovery sleep staging, subsequent alertness and psychomotor performance were evaluated in humans. Forty-five healthy male subjects were deprived of sleep for 24 h, then administered a single dose of triazolam or placebo using a double-blind procedure. Subjects then attempted to obtain recovery sleep under non-sleep-conducive conditions (sitting upright in a well-lit, crowded chamber) for the next 6 h, followed by 18 more hours of sleep deprivation. During all sleep deprivation periods subjects were tested bihourly on a performance assessment battery which included symbol digit modalities tests (SDMT), four-letter search (FLS), logical reasoning (LR), time estimation (TE), visual vigilance (VV), and short term memory (STM) tasks. Sleepiness levels were measured objectively with multiple sleep latency tests (MSLT) and subjectively with the Stanford Sleepiness Scale (SSS). Compared to placebo, all doses of triazolam resulted in increased amounts of stage 3-4 sleep, and the 0.5 mg dose significantly reduced awakenings (Ps less than 0.05). Although subjects receiving triazolam averaged 21-42 min more total sleep time (TST) than subjects receiving placebo, differences in TST were not statistically significant. Apparent triazolam-mediated benefits to sleep quality resulted in no obvious improvements in performance or alertness levels during subsequent sleep deprivation. It was concluded that the increases in stage 3-4 sleep amounts were most likely due to triazolam-mediated increases arousal thresholds, and the triazolam mediated changes in sleep parameters obtained in the present study were not indicative of substantial changes in the recuperative value of sleep.

CognitiveConstruct

LogicalReasoning

10.1177/070674378803300802

Canadian journal of psychiatry. Revue canadienne de psychiatrie

Can J Psychiatry

Reflections on the epistemology of psychiatry.

A re-examination of the theoretical basis of our practice of psychiatry (that is, its epistemology) reveals the insufficiency of the empirical, inductive approach which we have come to regard, too myopically, as the sine qua non of our science. Traditionally in psychiatry, the discipline of philosophy, of which epistemology is one of its major fields of endeavour, has generally come to be regarded as irrelevant or unreliable as a source of true knowledge. But an objective look at our variegated practice of psychiatry--roughly divided into two groups--the biological on the one side and the psychosocial on the other--reveals a glaring lack of integration, cohesion, or synthesis in basic theory. While analysis is the prime modus operandi of science, synthesis is the main objective of philosophy. While we subscribe to various operational theories to explain how our various procedures work, we lack an overarching, unified, general theory to subsume them. Hence we lack a truly holistic concept of the person who is our patient. In this we are much in need of the discipline of philosophy, which promotes clarity of thought, breadth of comprehension, and systematic (logical) reasoning. Psychiatrists acquire more of this philosophic expertise through collaboration with professional philosophers (epistemologists in particular) and through the introduction into our graduate psychiatric training programs of some specific course content from the literature of philosophy. As a preliminary suggestion for this, an "Annotated Reading List" is appended.

CognitiveConstruct

LogicalReasoning

10.1080/00221325.1988.10532150

The Journal of genetic psychology

J Genet Psychol

The relation between young children's cognitive role-taking and mothers' preference for a conflict-inducing childrearing method.

In this study, we examined children's cognitive role-taking in relation to their mothers' choices of techniques to solve domestic dilemmas involving children's misbehavior, social skills, and logical reasoning. Results showed that a mother's preference for the childrearing strategy known as distancing, which uses a Socratic or dialectical inquiry to create cognitive conflict in the child, bore a significant association to her child's advancement in cognitive role-taking skill. This finding is discussed in relation to theories of cognitive development that postulate that mental conflict or tension stimulates cognitive growth. Practical factors that might inhibit mothers from making effective use of the distancing technique are also considered.

CognitiveConstruct

LogicalReasoning

10.1016/0306-4530(88)90060-1

Psychoneuroendocrinology

Psychoneuroendocrinology

Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women.

The effect of estrogen and/or androgen replacement therapy on several aspects of cognitive functioning in surgically menopausal women was tested in a prospective, crossover design. Women who received either a combined estrogen-androgen preparation, estrogen alone, or androgen alone had scores on two tests of short-term memory, a test of long-term memory and a test of logical reasoning that were not different during the postoperative treatment phase compared to their preoperative performance. However, oophorectomized women who received placebo had lower scores on all four measures of cognitive functioning postoperatively, coincident with their significantly lower concentrations of plasma estradiol and testosterone. Patients who had a hysterectomy but whose ovaries were retained showed stability both in cognitive performance and in circulating sex steroid concentrations. These findings suggest that the drastic change in endocrine milieu following surgical menopause may have a direct, albeit modest, effect on aspects of cognitive functioning. Possible mechanisms of action of the sex hormones on cognitive functioning in women are discussed.

CognitiveConstruct

LogicalReasoning

10.1007/978-3-642-73288-1_18

Psychopharmacology series

Psychopharmacol Ser

Beta-carbolines as tools in memory research: human data with the beta-carboline ZK 93426.

The discovery of substances which bind with high affinity to benzodiazepine receptors but have no pharmacological effects (antagonists) or effects opposite to those of benzodiazepines (inverse agonists) have introduced a new approach to elucidating mechanisms underlying memory and other cognitive processes. Since benzodiazepines induce anterograde amnesia and sedation, these substances should show an opposite effect and so enhance memory and/or increase vigilance. In the present report we present data obtained in humans with a benzodiazepine receptor antagonist with weak inverse agonist properties, ZK 93426. The drug was given intravenously to human volunteers in double-blind, placebo-controlled designs and performance on several psychometric tests was evaluated. In a general estimation of behavioural changes volunteers experienced a stimulatory, activating effect of the drug. An improvement was observed in two cognitive tasks, the logical reasoning task and the pictures difference task, which estimate concentration and attentional processes respectively. No effects were found in a letter cancellation test or in time estimation. In another study utilizing EEG recording, we demonstrated that ZK 93426 increased wakefulness (vigilance) in healthy subjects during the daytime. The effect of ZK 93426 upon memory processes was also investigated utilizing a visual memory test and word lists. A slight improvement in some memory processes, especially long-term retrieval, was found. The present data suggest that benzodiazepine receptor antagonists with weak inverse intrinsic activity possess some effects opposite to those of benzodiazepines.

CognitiveConstruct

LogicalReasoning

10.1007/BF00172956

Psychopharmacology

Psychopharmacology (Berl)

Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93 426: antagonism of lormetazepam's psychotropic effects.

The effects of lormetazepam (0.03 mg/kg IV) a benzodiazepine (BZ) derivative in combination with ZK 93 426 (0.04 mg/kg IV) a beta-carboline, benzodiazepine receptor antagonist were evaluated in humans. Independently, the effects of ZK 93 426 on its own were investigated. A psychometric test battery to evaluate sedation (visual analog scales (VAS), anxiolysis (state-trait-anxiety inventory scale (STAIG X1) and cognitive functions [logical reasoning test (LR), letter detection test (LD)] was applied before and several hours after initiation of treatment. Multiple sleep latency test (MSLT), which measures day time sleepiness, was also applied. Vigilosomnograms analysed from standard EEG recordings were evaluated shortly before and for 1 h after treatment. Treatment started with an intravenous injection of either lormetazepam (LMZ) or placebo (PLA), which was followed 30 min later by administration of either ZK 93 426 or placebo; thus four treatment groups were created (PLA + PLA, LMZ + PLA, LMZ + ZK 93 426 and PLA + ZK 93 426). ZK 93 426 antagonized the sedative and hypnotic effect of LMZ as estimated by MSLT and vigilosomnograms, respectively. Impairment of cognitive functions (LR and LD) induced by LMZ was also antagonized by ZK 93 426. ZK 93 426 had no effect on the changes in the time estimation seen in the LMZ group. Furthermore, ZK 93 426 on its own increased vigilance (alertness) as measured by the vigilosomnogram. A competitive antagonism at the benzodiazepine binding site between ZK 93 426 and LMZ is suggested by their combination effects; the intrinsic activity of ZK 93 426 seems to be due to its weak partial inverse agonist component.

CognitiveConstruct

LogicalReasoning

Child development

Child Dev

Early function concepts: their development and relation to certain mathematical and logical abilities.

Cognition of functions (i.e., y = f(x)) has been identified as an achievement of early childhood. To investigate the development of function concepts and their relation to mathematical and logical abilities typically acquired during the age period of 5-7 years, 72 children in this age range were tested on nonnumerical function tasks (functions as exchange of properties, functions as displacement of positions, and functions as preservation of structure), numerical tasks (number conservation and arithmetic problems), and aspects of logical reasoning (class inclusion, class vicariance, and seriation). Orderly developmental trends were found in function task performance, with younger children manifesting limited success through trial-and-error strategies and older children achieving substantial success with anticipatory strategies. Moreover, certain function abilities were associated with the numerical domain, whereas others were associated with the logical domain. The findings are consistent with the developmental model of Piaget et al. according to which cognition of functions lays the groundwork for reversible operations, but also suggest that this development occurs through parallel processes within separate conceptual domains.

CognitiveConstruct

LogicalReasoning

10.1016/0361-9230(87)90100-6

Brain research bulletin

Brain Res Bull

Clinical perspectives of beta-carbolines from first studies in humans.

First results from studies in healthy subjects with the beta-carbolines ZK 91 296, ZK 95 962 and ZK 93 426 are reviewed. ZK 91 296 and ZK 95 962, characterized as partial benzodiazepine agonists in preclinical research, were unable to induce some typical benzodiazepine effects like sedation when administered intravenously in high doses. ZK 95 962, reported to be effective in photoepileptic patients, was able to reverse lormetazepam-induced sleep as documented by EEG-parameters. The benzodiazepine receptor antagonist ZK 93 426 dose-dependently elicited alertness, restlessness and mild apprehension--symptoms opposite those known for the benzodiazepines. The activating effect of ZK 93 426 was confirmed by the results from e.g., self-rating scales and the logical reasoning test. In another placebo-controlled study comparing the effects of ZK 93 426 alone and in combination with lormetazepam vigilosomnograms obtained after ZK 93 426 alone clearly confirmed the activating effect. In combination with lormetazepam ZK 93 426 was able to reverse the benzodiazepine induced sleep. The attenuation of benzodiazepine effects was also evident from multiple sleep latency tests. Our results support findings from animal experiments which classify these beta-carbolines as benzodiazepine receptor ligands with partial agonist and antagonist properties. beta-Carbolines may prove to be beneficial drugs in the treatment of anxiety, convulsions and diseases with an impairment of cognitive functions as well as in the reversal of unwanted benzodiazepine effects.

CognitiveConstruct

LogicalReasoning

Journal of neural transmission. Supplementum

J Neural Transm Suppl

Abstract reasoning in age-related neurological disease.

Subjects with a variety of neurological disorders including Alzheimer's disease (AD) were tested for abstract reasoning ability with two new tests that do not involve high-order language, memory, or visuospatial skills. All groups performed at the normal level except the patients with AD, who performed poorly on the test of logical reasoning ability, but relatively well on the test of the ability to recognize relationships between common objects. The results suggest that in AD, relational abilities may remain intact well into the disease, whereas generational abilities may be among the cognitive skills that are impaired early in the course of the disease.

CognitiveConstruct

LogicalReasoning

10.1007/BF00207229

Psychopharmacology

Psychopharmacology (Berl)

Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93,426: preliminary observations on psychotropic activity.

The beta-carboline ZK 93,426, a benzodiazepine receptor antagonist, was administered intravenously to human volunteers at two different doses (0.01 mg/kg, 0.04 mg/kg) according to a double-blind, placebo controlled design. Vital functions (i.e. blood pressure, heart rate, ECG, EEG), peripheral (finger) skin temperature and performance in psychometric tests for psychotropic and cognitive effects were evaluated. Blood samples were collected in addition and certain pharmacokinetic parameters were estimated. ZK 93,426 in both doses was well tolerated and exhibited no side effects. A decrease in peripheral skin temperature and heart rate was observed. In a general estimation of behavioural changes, volunteers experienced a stimulant and activating effect of the drug. An improvement in performance was observed in two cognitive tasks, the "logical reasoning task" and "pictures differences task" which estimated concentration and attention, respectively. No effects were found in time estimation. Plasma levels 5 min after intravenous administration of ZK 93 426 were 16 +/- 10 ng/ml and 52 +/- 31 ng/ml for 0.01 mg/kg and 0.04 mg/kg, respectively. Total clearance was calculated as 46 +/- 22 ml/min/kg (0.04 mg/kg).

CognitiveConstruct

LogicalReasoning

10.3758/bf03202507

Memory & cognition

Mem Cognit

Logical reasoning, world knowledge, and mental imagery: interconnections in cognitive processes.

CognitiveConstruct

LogicalReasoning

10.1111/j.1365-2125.1986.tb05229.x

British journal of clinical pharmacology

Br J Clin Pharmacol

Zopiclone produces effects on human performance similar to flurazepam, lormetazepam and triazolam.

The cognitive function and psychomotor performance of 10 healthy male volunteers were measured following single oral doses of: zopiclone (7.5 mg), flurazepam (15 mg), lormetazepam (1 mg), triazolam (0.25 mg) and placebo. The performance tests selected (stroop task, five choice serial reaction time, memory span, logical reasoning, mood and saccadic eye movement analysis) were thought to reflect aspects of normal daily activity. The tests demonstrated a clear reduction of performance for all active treatments. No drug emerged as the most potent sedative overall, as each of the tests was affected to a different degree by each drug. Drug effects were not qualitatively different between active treatments so that zopiclone was indistinguishable from the three benzodiazepines with which it was compared.

CognitiveConstruct

LogicalReasoning

10.3109/07420528609066364

Chronobiology international

Chronobiol Int

Interactions between inter-individual and inter-task differences in the diurnal variation of human performance.

Thirty-six undergraduate subjects were divided into 'larks' and 'owls' by median split using the morningness test devised by Horne and Ostberg. Each was given a battery of two performance tests at six times of day, in a design that counter-balanced for practice effects. Oral temperatures were also recorded. Slight (1 hr) phase differences (in the predicted direction) were observed between 'larks' and 'owls' in temperature rhythm, and in the performance test that paralleled temperature (a serial search task). Much more striking differences, though, were observed in the cognitive (logical reasoning) performance test which (as predicted) peaked earlier in the day, on average, than the serial search task. Not only did 'larks' peak much earlier in the day than 'owls', but there were also quite dramatic differences between the two groups in amplitude and shape. Possible mechanisms regarding oscillatory control and performance strategy are discussed.

CognitiveConstruct

LogicalReasoning

Acta physiologica Scandinavica. Supplementum

Acta Physiol Scand Suppl

Animal experimentation ethics from an experimenter's point of view.

The experimental biologist faces two kinds of ethical problems: practical and philosophical. The practical problems comprise increased costs of experimental animals, and the risk of being harassed or even raided by animal activists. There is also today a growing bureaucratic ethics overhead that has to be paid for, one way or another. The philosophical problems are the true ethical problems. Most laws and regulations emphasize that pain and agony should be minimized, but it is shown that this is neither always necessary nor always adequate. Scientists expect logical reasoning and opinions based on facts, but it is easy to find examples that the public opinion is quite illogical concerning pain and agony. For instance, you may under certain circumstances very well torture and kill animals just for pleasure. Our present legislation should be amended so as to concur better with current public views on how animals should be treated. The Swedish Committees on Animal Experimentation Ethics were intended to help scientists understand the demands of the public opinion. It is doubtful if they have been successful. The ethics of animal experimentation are perforce centered on the experimenter. He alone, at the final moment, makes the decision whether or not to use and, eventually, to kill the animal. When he kills, he obviously has a reason for doing so, and has decided that the purpose justifies the action. With the very large increase in the number of animal experiments in the last few decades, society has justifiably become increasingly concerned about the ethical considerations involved.(ABSTRACT TRUNCATED AT 250 WORDS)

CognitiveConstruct

LogicalReasoning

10.1007/BF00310629

Psychopharmacology

Psychopharmacology (Berl)

Human cognitive function following binedaline (50 mg and 100 mg) and imipramine (75 mg): results with a new battery on tests.

The effects of two single oral doses of binedaline (50 and 100 mg), imipramine (75 mg) and placebo were compared on a range of psychological tasks (logical reasoning, the Stroop test, and five-choice serial reaction) in healthy young volunteers. The tasks, together with a mood adjective check-list, were completed prior to drug administration and 1, 2, 4 and 8 h post-dose. Binedaline had no significant effect on any of the task parameters. Imipramine impaired performance on all but the Stroop test at 2 h after drug administration. At 1, 2 and 4 h, ratings on the "deactivation" dimension of the mood adjective check-list were significantly higher following imipramine when compared to placebo. The results are discussed in terms of some general considerations about the selection and scoring of tasks to be used in the screening of drugs.

CognitiveConstruct

LogicalReasoning

10.2466/pms.1985.61.3f.1179

Perceptual and motor skills

Percept Mot Skills

Decrements in logical reasoning performance under conditions of sleep loss and physical exercise: the factor of sentence complexity.

Baddeley's Logical Reasoning Test was used in a series of Sustained Operations (SUSOP) studies involving 100 US Marine Corps enlisted subjects, to assess the effects of sleep loss and long-term physical exercise on the ability to process complex information. The percent correct answers to the eight Logical Reasoning sentence types involving different voice (active vs passive), use of negatives, and outcome (true vs false) were analyzed over three days across three levels of exercise and rest conditions in the seven studies. A multivariate analysis of variance indicated no differences on the baseline day among the seven studies. Analyses on the baseline day and throughout the next two continuous workdays (CWs) showed consistently higher percent correct for the actively worded than for the passively worded sentences. The sleep loss over the two CWs resulted in a significant decrease in percent correct for the statements which had active wording. Sleep loss had no effect on statements with passive wording. There were no differences in comprehension between groups which had different rest conditions (no rest, 3- or 4-hr. nap, 8-hr. sleep) between the two CWs for any of the sentences; and there was no recovery from prerest to postrest. Fatigue due to exercise during either CW had no effect on comprehension for any of the sentence types. The sleep loss effects on comprehension seem due to a lessening of the attention given to those more simple sentences in active voice, whereas increased arousal may have been elicited by the more complex sentences in passive voice. The increased attention to the passive statements may have overcome the effects of sleep loss. The present study shows the usefulness of analyzing responses to the logical reasoning test by sentence complexity for indicating selective cognitive changes in the processing of information.

CognitiveConstruct

LogicalReasoning

Aviation, space, and environmental medicine

Aviat Space Environ Med

The effects of mild hypoxia on a logical reasoning task.

In an attempt to replicate the findings of Crow and Kelman (1969) and Denison et al. (1966), which suggest that the performance of novel tasks can be impaired at altitudes below 3,050 m, 150 subjects were divided into five independent groups and their performance tested on a logical reasoning task. One group was tested at ground level in a lecture room; the remaining groups were tested in a decompression chamber, one at 305 m, one at 2,440 m, one at 3,050 m and one at 3,660 m. Significant differences were identified between the 'lecture room' and 'chamber' groups in both speed of work and error rate (p less than 0.05); this finding is interpreted as the effect of apprehension on the naive subjects. A significant difference was found between the group tested at 3660 m and the remaining groups for error rate (p less than 0.05); this finding is interpreted as the effect of apprehension on the naive subjects. A significant difference was found between the group tested at 3660 m and the remaining groups for error rate (p less than 0.05) but not for speed of work. However, no effect of altitude on the way in which the task was learned could be demonstrated.

CognitiveConstruct

LogicalReasoning

10.1111/j.1943-278x.1985.tb00943.x

Suicide & life-threatening behavior

Suicide Life Threat Behav

An empirical investigation of Shneidman's formulations regarding suicide.

This study of suicide notes involved the deduction of 50 protocol sentences that reflected important aspects of Shneidman's formulations regarding suicide. Independent judges noted the incidence of contents corresponding to the protocol sentences in 33 genuine and 33 simulated notes. Statements that were found significantly and more frequently in genuine notes included the following: the experience of adult trauma such as a calamitous relationship; a rejection; the withdrawal of a significant person resulting in despair; perceiving another as dooming one to the suicide; expressions of ambivalence; feelings of love, hate and other emotions; feelings of helplessness, pessimism and emotional confusion; appearing to be intoxicated by one's overpowering emotions and constricted perceptions; and the communications appearing to have unconscious implications. Statements of "egression" and more logical reasoning were more characteristic of the simulated notes. A frequency count in the genuine notes indicated that many protocol sentences were also very predictive of the content. Implications of the results are discussed.

CognitiveConstruct

LogicalReasoning

10.2165/00003495-198500294-00014

Drugs

Drugs

Logic and empiricism in the selection of antiarrhythmic agents. The role of drug combinations.

Advances in investigative techniques of cardiac arrhythmias through invasive procedures (clinical electrophysiology) or through ambulatory electrocardiographic monitoring provide a better understanding of the mechanism responsible for these disturbances and a better assessment of therapeutic efficacy. Yet, it cannot be inferred that the selection of antiarrhythmic agents is orientated in all cases by logical reasoning. Too many factors are unknown, especially those regarding the spontaneous mechanism of initiation of clinical arrhythmias. Patient management very often remains mainly empirical. The problem becomes even more complex when dealing with arrhythmias resistant to single-agent therapy. Drug combinations are then used, often successfully, particularly those combining membrane-stabilising agents with amiodarone or beta-adrenergic blocking agents or combining amiodarone with verapamil. Explanations of the efficacy of these combinations at reduced doses become less certain, but it is more important to achieve efficacy than to understand its mechanism, which does not always amount to a simple increase in plasma drug levels. When attempting to determine the reasons behind the theoretically logical selection of an antiarrhythmic agent, it appears that, in spite of advances in electrophysiology and pharmacology, the logic of this selection owes more to chance than to reason. The problem becomes further complicated when drug combinations are to be used which, in clinical practice, are often the therapeutic solution in difficult cases. Advances made in recent years bring up the question of knowing whether or not logic is near to replacing empiricism.

CognitiveConstruct

LogicalReasoning

10.1080/00221309.1983.9711489

The Journal of general psychology

J Gen Psychol

Psychological sexual identity and hemispheric orientation.

The study examines gender and psychological sexual identity as alternative bases for the development of hemispheric orientation. Hypotheses anticipated that females place greater reliance upon right hemisphere functions, such as imagery and emotion, whereas males place more emphasis upon left hemisphere functions, such as logical reasoning. This was extended to an examination of the roles of masculinity and femininity within genders upon hemispheric orientation. With a sample of 219 male and 221 female adults, it was found that the male-left hemisphere orientation/female-right hemisphere orientation dichotomy was supported in part. However, this relationship appears to be moderated by a second dimension: females appear more internally oriented, males more externally oriented.

CognitiveConstruct

LogicalReasoning

10.1016/0091-3057(83)90235-6

Pharmacology, biochemistry, and behavior

Pharmacol Biochem Behav

Circadian variation in effects of ethanol in man.

Twenty normal male volunteers received an intoxicating dose of oral ethanol (2 ml/kg vodka) and impairment of psychological functioning was documented over the succeeding 90 min. Half the subjects received ethanol at 0900 hr and half at 1800 hr. Those who received ethanol in the morning performed worse in tests of reaction time (p less than 0.002) and logical reasoning (p less than 0.002), even though blood alcohol levels were similar in the two groups. It is concluded that there is a circadian rhythm in the effects of ethanol in man.

CognitiveConstruct

LogicalReasoning

10.1007/BF00427573

Psychopharmacology

Psychopharmacology (Berl)

A comparison of some psychological and physiological effects exerted by zetidoline (DL308) and by oxazepam.

In a double-blind, balanced crossover study, eight healthy male volunteers ingested either DL-308 (10 mg), DL-308 (20 mg), oxazepam (30 mg) or placebo. Subjective estimates of coordination and anxiety, objective performance measurements and cardiovascular measurements were taken at 1, 3, 5 and 8 h after ingestion. DL-308 (20 mg) exerted a strong sedative effect as judged by self-reported coordination scores and performance on logical reasoning and reaction time tests. The effect was evident almost immediately and, on the coordination and reasoning tests, lasted up to 8 h following ingestion. Attention is drawn to the need to extend performance testing in order to maximise test sensitivity. No drug had any consistent or strong influence on cardiovascular measures.

CognitiveConstruct

LogicalReasoning

10.1161/01.hyp.4.2.226

Hypertension (Dallas, Tex. : 1979)

Hypertension

Cognitive processes in hypertension.

In 15 normotensive subjects, 17 newly diagnosed, untreated hypertensive patients, and 22 effectively treated hypertensive patients, a battery of neuropsychological tests was given. All subjects were neurologically asymptomatic. The neuropsychological battery included tests evaluating global cognitive functions (Card Sorting Test, Wechsler Memory Scale, Progressive Matrices 1938), as well as specific cognitive functions (Benton Test, subtests of the Wechsler-Bellevue Scale). Normotensive controls obtained better scores in all the tests. Statistical analysis of th scores suggests that hypertension is highly correlated with impairment of memory, logical reasoning, visuospatial organization, and attention. Therapy seems to impair attention, while the duration of disease seems to influence visuospatial performances.

CognitiveConstruct

LogicalReasoning

10.1016/0277-9536(82)90393-8

Social science & medicine (1982)

Soc Sci Med

Errors of intuitive logic among physicians.

The effectiveness of specific training in statistics and decision-making principles upon physicians' judgmental skills was assessed by means of problems of intuitive logical reasoning. The responses of 43 statistically sophisticated physicians (SP) were compared to those of 42 practicing physicians (PP), 43 clinical nurses (CN) and 41 hospital laborers (HL). On problems evaluating use of faulty heuristics in judgments of conditional probabilities, the SP group's responses were the most biased. The proportion of subjects displaying consistent use of a particular heuristic in solving the three problems were 0.36 (SP), 0.45 (PP), 0.35 (CN) and 0.41 (HL). On problems assessing use of prevalence rate data in estimating probabilities, SP performed substantially better than the other three groups: 34% of their responses were accurate. However, 37% of their responses reflected ignorance of prevalence information concepts. We conclude that intensive statistical and decision-making training of physicians is likely to be of only limited value for improving clinicians' judgmental skills.

CognitiveConstruct

LogicalReasoning

10.1002/1097-4679(198107)37:3<466::aid-jclp2270370303>3.0.co;2-i

Journal of clinical psychology

J Clin Psychol

Logical reasoning deficits in schizophrenia and brain damage.

Von Domarus and Arieti have theorized that failure to reason by conventional logical rules is at the root of schizophrenic thought disorder, but the available research on this view is inconclusive. We compared the performance of schizophrenics (N = 100), brain-damaged patients (N = 50) and psychiatric controls (N = 50) on closely matched measures of Overexpansive and "Von Domarus" (similarity implies identity) syllogistic reasoning errors. Before the samples were matched for education and intelligence, the brain-damaged and schizophrenic patients made more Overexpansive errors than the controls, but the Von Domarus error difference was not significant. After matching, both differences were nonsignificant. The results indicate that inability to use syllogistic reasoning properly is probably not the root cause of schizophrenic thought disorder.

CognitiveConstruct

LogicalReasoning

Child development

Child Dev

Dyadic interaction in a logical reasoning problem requiring inclusion ability.

This study involved a test of the hypothesis that dyadic performance is superior to the performance of children working alone because children in dyads are able to cooperatively coordinate their different perspectives. A novel task requiring inclusion reasoning was given to children 4--8 years old working in dyads and working alone. Dyadic performance was not superior and correct dyadic solution was frequently based on the incorrect child's compliance with the correct partner's judgment, a finding that is consistent with results of previous studies. Thus, the hypothesis was not supported because children working together did not do better than children working alone, and correct dyadic solutions were sometimes based on compliance rather than on cooperative coordination of perspectives.

CognitiveConstruct

LogicalReasoning

Revista. Centro de Estudos Demograficos (Portugal)

Rev Cent Estud Demograficos

[Some reflections concerning the definition of the purpose of the sociology of population].

CognitiveConstruct

LogicalReasoning

10.1007/BF00426908

Psychopharmacology

Psychopharmacology (Berl)

Paradoxical effects in sleep and performance of two doses of chlorpromazine.

Twenty-four subjects were given placebo, 25 mg, and 75 mg of chlorpromazine on three separate occasions. Twelve subjects were treated in the morning and tested for performance during the day. Twelve other subjects received the drug treatments in the evening. Both groups had their EEG stages of sleep recorded during the subsequent night. The low dose of drug shortened the REM/non-REM cycle length in comparison to the high dose, and placebo values were intermediate. In performance tests, visual integration time was impaired by the high dose of the drug. Logical reasoning was slowed by the high dose of the drug in comparison to the low dose, with placebo values intermediate between the two.

CognitiveConstruct

LogicalReasoning

Pathologie-biologie

Pathol Biol (Paris)

[Medical decision assistance. Logical method and application to thyroid diseases (author's transl)].

Medical diagnosis assistance is described in terms of step by step logical reasoning methods. Boolean functions, possibly connected with phi-fuzzy functions, and a theorem proving algorithm may be used at each step. The choice merely depends on the accuracy of diagnosis at a given step. Numerical results based on a study of patients with thyroid diseases are presented.

CognitiveConstruct

LogicalReasoning

10.1097/00005053-197609000-00007

The Journal of nervous and mental disease

J Nerv Ment Dis

A comparison of abstractive and nonabstractive deficits in schizophrenics and psychiatric controls.

Chapman and Chapman (Disordered Thought in Schizophrenia, Appleton-Century-Crofts, New York, 1973) have suggested that findings of abstract thinking deficits in schizophrenia could be functions of control task artifacts. This paper describes two projects in which the abilities of schizophrenics and psychiatric hospital controls who had been closely matched on a wide variety of vocabulary and nonvocabulary control tasks to perform several types of abstract thinking tasks were compared. No differences on the mean scores of the schizophrenic and control patients appeared on four of five measures used. On the fifth, a logical reasoning test, the schizophrenics were inferior to controls. The results suggest that many of the differences reported earlier between schizophrenics and nonschizophrenics on abstraction tasks may result from the heavy reliance of researchers on vocabulary as a control matching test, and its peculiar resistance to deterioration in schizophrenia. The results also suggest that inability to use logic properly may be.

CognitiveConstruct

LogicalReasoning

Undersea biomedical research

Undersea Biomed Res

Diver performance: the effect of cold.

Fifteen divers performed five tasks in water of temperatures 20 degrees C and 5 degrees C, using standard scuba equipment. A significant deterioration of performance occurred under the colder condition in: simple arithmetic 13%; logical reasoning 17%; word recall 37%; word recognition 11%; and manual dexterity 17%. Throughout each dive, rectal and five skin temperatures were monitored. Average fall in rectal temperature was 0.5 degrees C during 20 degrees C dives and 1.1 degrees C during 5 degrees C dives. Average body surface temperature fell by 5 degrees C and 12.5 degrees C respectively. Average heat losses calculated from the data were 95 kcal.m(-2).hr(-1) (20 degrees C dives) and 245 kcal.m(-2).hr(-1) (5 degrees C dives). The impairment in word recognition was significantly correlated with the fall in rectal temperature for the 5 degrees C dives. For other tests, the deterioration did not appear to be correlated with body-temperature changes, but rather, occurred rapidly upon cold water immersion. The significance of these findings is discussed in relation to current understanding of the mechanisms by which cold is thought to influence performance underwater.

CognitiveConstruct

LogicalReasoning

10.1111/j.2044-8295.1975.tb01433.x

British journal of psychology (London, England : 1953)

Br J Psychol

Diurnal variation in logical reasoning.

Subjects performed two tests of logical reasoning at each of six different times of day. In terms of speed, preformance on both tests was found to improve markedly from 08.00 to 14.00 and then to fall off fairly rapidly. Accuracy was found to decrease fairly linearly over the day. The results are interpreted as indicating that the different functions relating performance efficiency to time of day found by previous workers are due to differences in task demands rather than to individual differences. It is suggested that the larger the short-term memory component of a task the earlier in the day performance peaks.

CognitiveConstruct

LogicalReasoning

Neurologia, neurochirurgia i psychiatria polska

Neurol Neurochir Psychiatr Pol

[Monopolarity of decisive logical reasoning & bipolarity of feelings in normalcy & obsessions].

CognitiveConstruct

LogicalReasoning

10.1080/00221309.1946.10544530

The Journal of general psychology

J Gen Psychol

The influence of emotional subject matter on logical reasoning.

CognitiveConstruct

LogicalReasoning

10.4103/jehp.jehp_1492_20

Journal of education and health promotion

J Educ Health Promot

Analyzing the relationship between learning styles (Kolb and VARK) and creativity with the academic achievement of dental students.

One of the influential factors in students' learning is their learning styles which have the capacity to change. Furthermore, creativity is considered one of the essential cognitive features of humans. Thus, this study aimed to analyze the relationship between learning styles (Kolb and VARK) and emotional creativity with the academic achievement of dental students. In this descriptive-analytical study, the statistical population included dental students of the third semester and above (250 persons). The data collection tools included Kolb and VARK learning style questionnaires, Averill emotional creativity questionnaire, the total Grade Point Average (GPA), and the GPA over the past two semesters of students to measure academic achievement. The data were analyzed using the measures of the descriptive (mean and standard deviation) and the inferential statistics tests including one-sample -test, independent -test, correlation coefficients of Pearson, and Eta squared. Based on Kolb and VARK learning styles, the majority of the students had accommodating learning style (64%) and read-write style (31.6%) and also were single-styled (80.4%). No significant relationship was found between the learning styles (Kolb and VARK) and creativity with academic achievement. The students scored higher than average in emotional creativity and all of its three elements. Moreover, there was a significant relationship between emotional creativity and the gender of the students ( = 0.01). Female students showed higher emotional creativity (97.26 ± 10.34) compared to the male students (94.24 ± 8.96). There was no significant relationship between learning styles and emotional creativity of the students with their academic achievement. The accommodating and read-write learning styles were more prevalent among students and they showed high emotional creativity.

CognitiveConstruct

Creativity

10.3389/fpsyg.2021.706234

Frontiers in psychology

Front Psychol

The Influence of Trust on Creativity: A Review.

Examining the trust-creativity relationship is important to promote creativity and organizational innovation. The goal of this study is to investigate how trust influences creativity by summarizing existing findings of diverse empirical studies. The impact of trust at different levels on creativity primarily manifests in three ways: (1) individuals' cognition- and affect-based trust has a positive effect on creativity together with the role of trust-derived perspective taking in creativity; (2) interpersonal trust helps enhance the joint creativity of an entire group via mediators such as team communication and commitment together with trust-evoked safety and the motivation to risk proposing, sharing, accepting or adopting uncommon ideas; (3) group trust has a positive, mostly indirect effect on creativity via mediating variables such as collaborative culture/climate and team communication. Potential implications and avenues for future research are also discussed.

CognitiveConstruct

Creativity

10.1007/s00213-021-05970-0

Psychopharmacology

Psychopharmacology (Berl)

Effects of stimulant medication on divergent and convergent thinking tasks related to creativity in adults with attention-deficit hyperactivity disorder.

Common pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) are central nervous system stimulants acting as norepinephrine-dopamine reuptake inhibitors. The noradrenergic and dopaminergic systems have been shown to impact performance on tasks assessing creativity. Some previous studies suggest higher performance on creativity tasks in ADHD. Stimulant medication has been shown to differentially impact creativity in those without ADHD. However, the full range of effects of stimulant medication on creativity in those with ADHD is not known. This study examined the effects of stimulants on convergent and divergent tasks associated with creativity in adults with ADHD. Seventeen adults diagnosed with ADHD who were prescribed stimulant medication attended two counterbalanced sessions: one after taking their prescribed stimulant dose and one after the dose was withheld. Participants completed convergent problem-solving (anagrams, Compound Remote Associates) and divergent generative (letter/semantic fluency, Torrance Test for Creative Thinking (TTCT)-Verbal) tasks. There was a significant increase in words generated on the semantic fluency task for the stimulant session. Additionally, significant increases were found in the stimulant session for originality, flexibility, and fluency scores on the TTCT. Stimulant medication did not have an effect on any of the problem-solving tasks. Stimulant medication enhanced verbal fluency in adults with ADHD but had no effect on convergent abilities. Furthermore, stimulants enhanced fluency, flexibility, and originality scores on the TTCT. Therefore, stimulants appear to have positive effects on divergent task performance in adults with ADHD, but not convergent tasks. This finding warrants further studies into the specific roles of norepinephrine and dopamine in this effect.

CognitiveConstruct

Creativity

10.1016/j.neuroimage.2021.118531

NeuroImage

Neuroimage

Spontaneous and deliberate modes of creativity: Multitask eigen-connectivity analysis captures latent cognitive modes during creative thinking.

Despite substantial progress in the quest of demystifying the brain basis of creativity, several questions remain open. One such issue concerns the relationship between two latent cognitive modes during creative thinking, i.e., deliberate goal-directed cognition and spontaneous thought generation. Although an interplay between deliberate and spontaneous thinking is often implicated in the creativity literature (e.g., dual-process models), a bottom-up data-driven validation of the cognitive processes associated with creative thinking is still lacking. Here, we attempted to capture the latent modes of creative thinking by utilizing a data-driven approach on a novel continuous multitask paradigm (CMP) that widely sampled a hypothetical two-dimensional cognitive plane of deliberate and spontaneous thinking in a single fMRI session. The CMP consisted of eight task blocks ranging from undirected mind wandering to goal-directed working memory task, while also included two widely-used creativity tasks, i.e., alternate uses task (AUT) and remote association task (RAT). Using eigen-connectivity (EC) analysis on the multitask whole-brain functional connectivity (FC) patterns, we embedded the multitask FCs into a low-dimensional latent space. The first two latent components, as revealed by the EC analysis, broadly mapped onto the two cognitive modes of deliberate and spontaneous thinking, respectively. Further, in this low-dimensional space, both creativity tasks were located in the upper right corner of high deliberate and spontaneous thinking (creative cognitive space). Neuroanatomically, the creative cognitive space was represented by not only increased intra-network connectivity within executive control and default mode network, but also by higher coupling between the two canonical brain networks. Further, individual differences reflected in the low-dimensional connectivity embeddings were related to differences in deliberate and spontaneous thinking abilities. Altogether, using a continuous multitask paradigm and a data-driven approach, we provide initial empirical evidence for the contribution of both deliberate and spontaneous modes of cognition during creative thinking.

CognitiveConstruct

Creativity

10.7759/cureus.16697

Cureus

Cureus

Superlative Artistic Abilities in a Patient With Post-traumatic Brain Injury.

This case describes a patient who exhibits newfound superlative abilities in painting, music, philosophy, culinary, and performing arts after a traumatic brain injury (TBI) involving the frontal and temporal lobes. Such a dramatic change in de novo artistic behavior after brain injury is rare but has been reported in other patients with frontotemporal dementia, as well as other neurological diseases. Previous studies have shown that mild frontal cortical dysfunction likely plays a role in facilitating creative endeavors and that artistic circuitry is distributed throughout the brain. The neuronal reorganization which occurs after injuries enhances synapse formation and neural plasticity, which may contribute to the acceleration of artistic output after brain injury. This is likely an underdiagnosed phenomenon and a deeper understanding is required to allow clinicians to more effectively recognize and nurture newfound creativity in the setting of brain damage.

CognitiveConstruct

Creativity

10.1007/s10339-021-01047-0

Cognitive processing

Cogn Process

Correction to: Autism, autistic traits and creativity: a systematic review and meta-analysis.

In the original publication of the article, the first and last names of the authors are interchanged and published incorrectly. The correct author names are given below: Paola Pennisi, Laura Giallongo, Giusy Milintenda, Michela Cannarozzo.

CognitiveConstruct

Creativity

10.2196/30951

JMIR research protocols

JMIR Res Protoc

Web- and Mindfulness-Based Intervention to Prevent Chronic Pain After Cardiac Surgery: Protocol for a Pilot Randomized Controlled Trial.

Cardiac surgery is a frequently performed procedure. However, pain after cardiac surgery may become chronic (lasting >3 months) in adults. Once discharged from the hospital, patients are at greater risk of developing chronic postsurgical pain (CPSP) and of prolonged opioid use, as they need to self-manage their pain. Psychological risk and protective factors such as pain-related catastrophic thoughts and pain acceptance determine their ability to cope and their use of opioids, which is crucial for self-management of pain. Studies on mindfulness-based cognitive therapy (MBCT) have multiplied their potential effects on pain acceptance and catastrophic thoughts. However, web-based MBCT for the prevention of CPSP has not yet been examined. The aim of this study is to pilot test a 4-week-long web-based MBCT intervention for adults following discharge from the hospital by assessing the acceptability or feasibility of the intervention and examining preliminary effects on pain intensity, pain interference with activities and opioid use, and pain acceptance and catastrophic thoughts in the 6 months following surgery. A double-blinded pilot randomized controlled trial will be used to assess a web-based MBCT intervention. Patients will be selected according to the following criteria: age ≥18 years; first-time elective cardiac surgery via a median sternotomy; worst pain in the past week score ≥4/10; ability to understand and complete questionnaires in English; and ability to use an electronic device such as a smartphone, computer, or tablet. After baseline measures, 32 participants will be randomized into two groups: one receiving both the brief, 4-week-long web-based MBCT intervention and usual care (experimental group) and the other receiving only one standardized, web-based educational session with weekly reminders and usual care (attention control group). Peer-reviewed competitive funding was received from Florida State University's Council on Research & Creativity in January 2021, as well as research ethics approval from Florida State University's institutional review board. Recruitment began in June 2021. Unfortunately, because of the current COVID-19 pandemic, recruitment is not progressing as expected. Recruitment strategies are constantly monitored and updated according to latest data and restrictions surrounding the pandemic. This research is significant because it targets the trajectory of CPSP, a leading cause of disability and opioid misuse. This is the first study to assess MBCT for the prevention of CPSP after cardiac surgery in the recovery phase. This approach is innovative because it promotes self-management of pain through the modulation of individual factors. If successful, the intervention could be expanded to numerous populations at risk of chronic pain. DERR1-10.2196/30951.

CognitiveConstruct

Creativity