README.md

metadata

library_name: popV
license: cc-by-4.0
tags:
  - biology
  - genomics
  - single-cell
  - anndata_version:0.11.3
  - python_version:3.11.11
  - popV
  - 'tissue: diverse'

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Tabula Sapiens is a benchmark, first-draft human cell atlas of over 1.1M cells from 28 organs of 24 normal human subjects. This work is the product of the Tabula Sapiens Consortium. Taking the organs from the same individual controls for genetic background, age, environment, and epigenetic effects, and allows detailed analysis and comparison of cell types that are shared between tissues.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	11660	0.99	0.99	0.99	0.99	0.00	0.99	0.99	0.98	0.99
CD4-positive, alpha-beta T cell	9698	0.56	0.79	0.82	0.73	0.00	0.59	0.43	0.51	0.79
fibroblast	8490	0.79	0.80	0.94	0.70	0.00	0.64	0.70	0.66	0.89
CD8-positive, alpha-beta T cell	7669	0.73	0.78	0.81	0.74	0.00	0.74	0.58	0.61	0.80
neutrophil	6857	0.95	0.97	0.97	0.97	0.00	0.94	0.95	0.93	0.98
macrophage	6769	0.79	0.84	0.93	0.81	0.00	0.74	0.74	0.70	0.89
stromal cell of ovary	3561	0.95	0.94	0.91	0.68	0.00	0.39	0.96	0.92	0.98
endothelial cell	3306	0.69	0.73	0.91	0.62	0.00	0.54	0.65	0.63	0.83
basal cell	3386	0.89	0.86	0.89	0.68	0.00	0.63	0.85	0.82	0.93
plasma cell	2769	0.98	0.98	0.97	0.97	0.00	0.98	0.98	0.97	0.99
bladder urothelial cell	2725	0.99	0.97	0.97	0.65	0.00	0.60	0.98	0.96	0.99
monocyte	2546	0.43	0.41	0.77	0.47	0.00	0.26	0.50	0.52	0.59
mesenchymal stem cell	2373	0.89	0.81	0.90	0.40	0.00	0.10	0.90	0.81	0.91
smooth muscle cell	1899	0.72	0.69	0.88	0.69	0.00	0.64	0.73	0.72	0.81
classical monocyte	1761	0.59	0.62	0.75	0.43	0.00	0.57	0.59	0.64	0.71
luminal epithelial cell of mammary gland	1527	0.98	0.08	0.96	0.72	0.00	0.60	0.98	0.96	0.99
capillary endothelial cell	1503	0.69	0.65	0.88	0.53	0.00	0.55	0.67	0.65	0.78
erythrocyte	1475	0.97	0.96	0.95	0.96	0.00	0.96	0.95	0.96	0.97
natural killer cell	1495	0.72	0.75	0.75	0.67	0.00	0.73	0.67	0.70	0.75
enterocyte of epithelium proper of duodenum	1351	0.91	0.49	0.81	0.41	0.00	0.34	0.90	0.89	0.94
stratified squamous epithelial cell	1234	0.84	0.78	0.87	0.71	0.00	0.68	0.84	0.82	0.88
acinar cell of salivary gland	1210	0.95	0.85	0.94	0.61	0.00	0.43	0.95	0.93	0.97
pulmonary alveolar type 2 cell	1212	0.97	0.96	0.97	0.83	0.00	0.91	0.97	0.96	0.98
conjunctival epithelial cell	1173	0.92	0.76	0.85	0.51	0.00	0.31	0.94	0.90	0.95
pericyte	1110	0.64	0.58	0.84	0.53	0.00	0.55	0.67	0.66	0.75
luminal cell of prostate epithelium	1066	0.90	0.85	0.92	0.76	0.00	0.65	0.94	0.91	0.95
cardiac endothelial cell	940	0.94	0.91	0.92	0.47	0.00	0.20	0.95	0.88	0.97
naive thymus-derived CD4-positive, alpha-beta T cell	970	0.21	0.04	0.32	0.06	0.00	0.22	0.22	0.28	0.29
kidney epithelial cell	954	0.99	0.89	0.94	0.52	0.00	0.02	0.99	0.98	0.99
hepatocyte	764	1.00	0.99	0.95	0.64	0.00	0.70	0.99	0.96	0.99
blood vessel smooth muscle cell	630	0.73	0.49	0.89	0.42	0.00	0.21	0.89	0.76	0.91
enterocyte of epithelium proper of ileum	640	0.97	0.01	0.79	0.36	0.00	0.02	0.98	0.95	0.97
T cell	645	0.47	0.22	0.57	0.08	0.00	0.24	0.39	0.38	0.56
mast cell	582	0.88	0.85	0.96	0.83	0.00	0.91	0.91	0.87	0.93
skeletal muscle satellite stem cell	589	0.96	0.94	0.96	0.80	0.00	0.81	0.95	0.91	0.97
regular atrial cardiac myocyte	555	0.83	0.81	0.82	0.28	0.00	0.09	0.91	0.91	0.94
pancreatic acinar cell	560	0.95	0.26	0.93	0.55	0.00	0.45	0.98	0.96	0.98
intermediate monocyte	535	0.38	0.13	0.55	0.20	0.00	0.20	0.35	0.44	0.51
mature NK T cell	547	0.37	0.42	0.54	0.35	0.00	0.45	0.35	0.43	0.55
mononuclear phagocyte	460	0.39	0.00	0.92	0.14	0.00	0.01	0.63	0.48	0.59
fibroblast of breast	499	0.81	0.00	0.98	0.20	0.00	0.42	0.84	0.70	0.94
vascular associated smooth muscle cell	478	0.66	0.06	0.76	0.22	0.00	0.39	0.59	0.61	0.69
vein endothelial cell	461	0.42	0.15	0.74	0.23	0.00	0.32	0.46	0.43	0.59
CD4-positive, alpha-beta thymocyte	457	0.39	0.00	0.57	0.24	0.00	0.36	0.34	0.32	0.61
enterocyte of epithelium of large intestine	426	0.77	0.28	0.56	0.42	0.00	0.22	0.78	0.83	0.79
myofibroblast cell	429	0.60	0.25	0.82	0.46	0.00	0.41	0.61	0.58	0.77
thymic fibroblast type 2	439	0.57	0.00	0.70	0.15	0.00	0.12	0.68	0.55	0.63
corneal epithelial cell	393	0.90	0.01	0.92	0.81	0.00	0.89	0.96	0.93	0.96
spermatid	412	0.96	0.00	0.96	0.83	0.00	0.97	0.98	0.96	0.98
duct epithelial cell	356	0.83	0.59	0.85	0.56	0.00	0.48	0.86	0.77	0.89
mesenchymal stem cell of adipose tissue	344	0.26	0.01	0.65	0.38	0.00	0.22	0.29	0.33	0.52
basal cell of prostate epithelium	350	0.73	0.14	0.89	0.41	0.00	0.60	0.88	0.72	0.86
endothelial cell of artery	362	0.52	0.45	0.78	0.46	0.00	0.57	0.63	0.55	0.76
stromal cell	340	0.60	0.03	0.47	0.43	0.00	0.26	0.77	0.69	0.86
thymic fibroblast type 1	333	0.29	0.01	0.84	0.22	0.00	0.04	0.66	0.43	0.49
pulmonary alveolar type 1 cell	314	0.95	0.95	0.96	0.88	0.00	0.94	0.97	0.94	0.97
spermatocyte	298	0.89	0.00	0.94	0.46	0.00	0.68	0.97	0.96	0.96
pancreatic ductal cell	271	0.87	0.52	0.90	0.67	0.00	0.43	0.96	0.94	0.96
regulatory T cell	279	0.07	0.01	0.26	0.08	0.00	0.22	0.30	0.34	0.35
ventricular cardiac muscle cell	241	0.34	0.03	0.75	0.32	0.00	0.46	0.82	0.81	0.86
endothelial cell of lymphatic vessel	250	0.69	0.57	0.87	0.57	0.00	0.60	0.60	0.62	0.72
hematopoietic precursor cell	221	0.63	0.68	0.73	0.61	0.00	0.46	0.59	0.59	0.76
retinal blood vessel endothelial cell	221	0.22	0.00	0.77	0.17	0.00	0.00	0.61	0.50	0.56
small intestine goblet cell	220	0.85	0.66	0.90	0.71	0.00	0.47	0.90	0.85	0.90
gamma-delta T cell	168	0.20	0.15	0.66	0.11	0.00	0.37	0.62	0.45	0.65
fibroblast of cardiac tissue	183	0.94	0.49	0.93	0.07	0.00	0.21	0.71	0.64	0.93
paneth cell of epithelium of small intestine	178	0.51	0.49	0.71	0.17	0.00	0.31	0.59	0.61	0.77
club cell	162	0.81	0.75	0.85	0.57	0.00	0.71	0.78	0.70	0.86
intestinal crypt stem cell of colon	171	0.76	0.61	0.55	0.36	0.00	0.16	0.85	0.80	0.85
progenitor cell of mammary luminal epithelium	174	0.99	0.00	0.96	0.94	0.00	0.92	0.96	0.93	0.99
epithelial cell	173	0.91	0.67	0.94	0.44	0.00	0.45	0.92	0.90	0.91
basophil	162	0.42	0.07	0.94	0.35	0.00	0.77	0.77	0.69	0.83
large intestine goblet cell	142	0.88	0.71	0.85	0.51	0.00	0.45	0.94	0.86	0.91
eye photoreceptor cell	143	0.88	0.88	0.92	0.87	0.00	0.90	0.97	0.94	0.95
epithelial cell of uterus	150	0.93	0.43	0.91	0.30	0.00	0.50	0.88	0.82	0.95
enterocyte of epithelium proper of small intestine	136	0.38	0.00	0.59	0.29	0.00	0.01	0.60	0.55	0.72
tissue-resident macrophage	118	0.60	0.00	0.78	0.32	0.00	0.20	0.48	0.46	0.71
acinar cell	141	0.80	0.60	0.83	0.75	0.00	0.79	0.89	0.88	0.90
non-classical monocyte	136	0.29	0.28	0.27	0.07	0.00	0.22	0.27	0.34	0.43
lung ciliated cell	131	0.78	0.58	0.98	0.74	0.00	0.91	0.96	0.89	0.96
activated CD8-positive, alpha-beta T cell	109	0.35	0.00	0.72	0.02	0.00	0.04	0.29	0.28	0.38
alveolar adventitial fibroblast	111	0.72	0.05	0.89	0.21	0.00	0.57	0.54	0.73	0.85
naive thymus-derived CD8-positive, alpha-beta T cell	118	0.15	0.00	0.39	0.07	0.00	0.15	0.14	0.12	0.33
adventitial cell	106	0.13	0.00	0.74	0.12	0.00	0.31	0.28	0.29	0.62
respiratory goblet cell	105	0.48	0.57	0.81	0.47	0.00	0.55	0.60	0.58	0.77
theca cell	101	0.63	0.08	0.80	0.34	0.00	0.70	0.77	0.58	0.81
myeloid leukocyte	93	0.17	0.00	0.73	0.14	0.00	0.19	0.23	0.14	0.54
keratocyte	103	0.30	0.00	0.56	0.06	0.00	0.14	0.52	0.38	0.35
enteroglial cell	89	0.84	0.69	0.94	0.80	0.00	0.75	0.96	0.83	0.86
erythroid progenitor cell	92	0.59	0.59	0.69	0.61	0.00	0.52	0.65	0.65	0.70
innate lymphoid cell	90	0.17	0.18	0.34	0.31	0.00	0.22	0.19	0.19	0.37
myometrial cell	86	0.78	0.00	0.78	0.15	0.00	0.21	0.64	0.53	0.80
endothelial cell of vascular tree	90	0.45	0.15	0.54	0.54	0.00	0.21	0.50	0.46	0.68
hematopoietic stem cell	91	0.74	0.65	0.77	0.72	0.00	0.64	0.79	0.79	0.85
salivary gland cell	88	0.54	0.00	0.89	0.57	0.00	0.67	0.54	0.58	0.88
granulocyte	76	0.23	0.03	0.50	0.35	0.00	0.15	0.24	0.19	0.47
CD8-positive, alpha-beta thymocyte	72	0.24	0.00	0.39	0.17	0.00	0.18	0.24	0.25	0.44
ciliated columnar cell of tracheobronchial tree	61	0.19	0.28	0.96	0.52	0.00	0.78	0.90	0.83	0.96
intrahepatic cholangiocyte	49	0.99	0.05	0.95	0.27	0.00	0.55	0.97	0.87	0.99
mural cell	73	0.35	0.10	0.86	0.13	0.00	0.31	0.61	0.54	0.78
intestinal crypt stem cell of small intestine	56	0.24	0.27	0.32	0.16	0.00	0.04	0.34	0.39	0.47
activated CD4-positive, alpha-beta T cell	77	0.04	0.00	0.32	0.00	0.00	0.14	0.13	0.13	0.28
myeloid dendritic cell	46	0.14	0.15	0.41	0.22	0.00	0.11	0.16	0.12	0.23
Mueller cell	47	0.54	0.34	0.59	0.64	0.00	0.72	0.88	0.72	0.82
fast muscle cell	52	0.71	0.56	0.93	0.74	0.00	0.88	0.81	0.81	0.93
platelet	37	0.91	0.90	0.95	0.83	0.00	0.70	0.90	0.69	0.93
myoepithelial cell	41	0.76	0.41	0.72	0.43	0.00	0.38	0.62	0.38	0.89
common myeloid progenitor	53	0.54	0.46	0.76	0.30	0.00	0.38	0.62	0.68	0.66
thymocyte	42	0.00	0.00	0.33	0.33	0.00	0.39	0.33	0.21	0.67
intestinal tuft cell	26	0.68	0.58	0.92	0.58	0.00	0.59	0.96	0.81	0.88
pancreatic stellate cell	44	0.00	0.00	0.88	0.33	0.00	0.00	0.54	0.31	0.78
tendon cell	35	0.43	0.00	0.52	0.44	0.00	0.30	0.45	0.21	0.67
microglial cell	41	0.07	0.00	0.53	0.12	0.00	0.15	0.20	0.15	0.34
muscle cell	47	0.71	0.00	0.95	0.74	0.00	0.91	0.80	0.84	0.95
enterocyte of epithelium proper of jejunum	52	0.00	0.00	0.20	0.27	0.00	0.11	0.55	0.37	0.63
mesothelial cell	34	0.67	0.65	0.86	0.75	0.00	0.41	0.44	0.72	0.72
colon endothelial cell	43	0.05	0.05	0.68	0.07	0.00	0.21	0.26	0.33	0.46
colon macrophage	35	0.19	0.00	0.76	0.04	0.00	0.03	0.24	0.18	0.57
serous cell of epithelium of trachea	27	0.37	0.00	0.79	0.25	0.00	0.10	0.38	0.39	0.76
ciliated epithelial cell	34	0.90	0.00	0.96	0.48	0.00	0.85	0.96	0.86	0.94
Schwann cell	28	0.73	0.56	0.60	0.42	0.00	0.46	0.61	0.55	0.74
supporting cell of vestibular epithelium	31	0.86	0.12	0.52	0.64	0.00	0.36	0.98	0.77	0.94
mucus secreting cell	24	0.57	0.11	0.78	0.21	0.00	0.22	0.62	0.55	0.78
enteroendocrine cell of small intestine	25	0.64	0.10	0.78	0.55	0.00	0.67	0.86	0.68	0.78
ovarian surface epithelial cell	19	0.55	0.33	0.80	0.60	0.00	0.17	0.84	0.61	0.89
transit amplifying cell of colon	23	0.56	0.35	0.46	0.13	0.00	0.06	0.53	0.42	0.67
glandular epithelial cell	26	0.67	0.11	0.67	0.21	0.00	0.59	0.98	0.62	0.89
melanocyte	24	0.75	0.51	0.70	0.36	0.00	0.53	0.81	0.57	0.94
tracheal goblet cell	20	0.00	0.19	0.58	0.67	0.00	0.40	0.75	0.63	0.74
hepatic stellate cell	26	0.36	0.00	0.71	0.13	0.00	0.15	0.54	0.38	0.69
bronchial smooth muscle cell	26	0.00	0.00	0.56	0.11	0.00	0.33	0.35	0.33	0.53
paneth cell of colon	21	0.58	0.29	0.50	0.41	0.00	0.18	0.77	0.34	0.88
tongue muscle cell	18	0.50	0.00	0.81	0.31	0.00	0.36	0.58	0.32	0.77
leukocyte	28	0.16	0.07	0.19	0.00	0.00	0.00	0.14	0.11	0.21
tuft cell of colon	32	0.00	0.00	0.72	0.37	0.00	0.70	0.89	0.83	0.85
slow muscle cell	19	0.70	0.25	0.73	0.40	0.00	0.64	0.76	0.73	0.80
ionocyte	13	0.52	0.18	0.76	0.46	0.00	0.06	0.81	0.67	0.86
connective tissue cell	20	0.00	0.00	0.95	0.00	0.00	0.00	0.56	0.24	0.69
neuro-medullary thymic epithelial cell	12	0.34	0.35	0.73	0.36	0.00	0.25	0.38	0.35	0.46
sebum secreting cell	18	0.00	0.02	0.77	0.16	0.00	0.12	0.81	0.58	0.83
endothelial cell of arteriole	11	0.00	0.00	0.67	0.00	0.00	0.26	0.42	0.32	0.62
male germ cell	12	0.00	0.00	0.80	0.00	0.00	0.21	0.96	0.81	0.96
type B pancreatic cell	10	0.80	0.00	0.84	0.86	0.00	0.74	0.95	0.86	0.95
hematopoietic cell	10	0.00	0.00	0.53	0.00	0.00	0.18	0.62	0.42	0.86
plasmacytoid dendritic cell	5	0.13	0.29	0.33	0.22	0.00	0.06	0.35	0.17	0.35
neuron	4	0.00	0.00	0.89	0.21	0.00	0.29	0.44	0.46	0.89
myeloid cell	5	0.00	0.00	0.00	0.00	0.00	0.07	0.22	0.10	0.25
myo-medullary thymic epithelial cell	3	0.33	0.00	0.80	0.33	0.00	0.44	0.57	0.40	0.67
Langerhans cell	10	0.00	0.00	0.67	0.25	0.00	0.42	0.32	0.34	0.63
interstitial cell of Cajal	7	0.00	0.00	1.00	0.15	0.00	0.00	0.70	0.56	0.86
retinal pigment epithelial cell	6	0.92	0.00	0.50	0.80	0.00	0.92	1.00	0.92	1.00
peritubular myoid cell	8	0.32	0.00	0.55	0.00	0.00	0.00	0.35	0.35	0.43
spermatogonium	10	0.00	0.00	0.50	0.00	0.00	0.25	0.82	0.86	0.75
retinal bipolar neuron	10	0.00	0.18	0.46	0.40	0.00	0.26	0.76	0.67	0.67
endothelial cell of venule	7	0.00	0.00	0.73	0.00	0.00	0.00	0.73	0.30	0.00
vestibular dark cell	5	0.00	0.00	0.33	0.20	0.00	0.09	1.00	0.73	0.80
pancreatic A cell	2	0.67	0.00	0.67	1.00	0.00	1.00	1.00	1.00	1.00
type L enteroendocrine cell	4	0.00	0.00	0.00	0.00	0.00	0.57	1.00	0.44	0.40
medullary thymic epithelial cell	3	0.00	0.00	0.80	0.00	0.00	0.03	1.00	0.67	0.50
adipocyte	2	0.00	0.00	0.50	0.00	0.00	0.20	0.22	0.12	0.29
transit amplifying cell of small intestine	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
taste receptor cell	3	0.00	0.00	0.80	0.00	0.00	0.07	0.50	0.09	0.80
enterochromaffin-like cell	2	0.00	0.00	0.00	0.00	0.00	1.00	1.00	0.40	0.00
enteroendocrine cell	4	0.00	0.33	1.00	0.57	0.00	0.55	0.89	0.44	0.89
pulmonary ionocyte	2	0.00	0.00	0.67	0.00	0.00	0.21	1.00	1.00	1.00
glial cell	1	0.00	0.00	0.50	0.00	0.00	0.10	0.40	0.15	0.67
oocyte	5	0.00	0.04	0.89	0.89	0.00	0.71	1.00	1.00	1.00
serous cell of epithelium of bronchus	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
radial glial cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Leydig cell	3	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.33	0.00
pancreatic D cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
T follicular helper cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
retina horizontal cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
erythroid lineage cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pancreatic PP cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
epithelial fate stem cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
mesenchymal cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	102833	0.99	0.99	0.99	0.99	0.00	0.99	0.99	0.98	0.99
CD4-positive, alpha-beta T cell	87430	0.57	0.78	0.87	0.83	0.00	0.57	0.45	0.52	0.82
fibroblast	74840	0.79	0.74	0.97	0.85	0.00	0.86	0.70	0.66	0.93
CD8-positive, alpha-beta T cell	68607	0.73	0.77	0.87	0.82	0.00	0.72	0.59	0.62	0.82
neutrophil	62682	0.95	0.97	0.98	0.98	0.00	0.94	0.95	0.93	0.98
macrophage	62296	0.79	0.83	0.95	0.87	0.00	0.77	0.75	0.70	0.91
stromal cell of ovary	31442	0.95	0.67	0.94	0.89	0.00	0.95	0.96	0.92	0.99
endothelial cell	30391	0.70	0.69	0.96	0.82	0.00	0.81	0.66	0.65	0.91
basal cell	30140	0.88	0.80	0.94	0.81	0.00	0.84	0.85	0.83	0.94
plasma cell	24580	0.98	0.97	0.98	0.97	0.00	0.97	0.98	0.97	0.99
bladder urothelial cell	24516	0.98	0.96	0.98	0.78	0.00	0.95	0.98	0.97	0.99
monocyte	23207	0.44	0.31	0.86	0.73	0.00	0.59	0.51	0.53	0.72
mesenchymal stem cell	21124	0.89	0.73	0.95	0.72	0.00	0.94	0.91	0.82	0.95
smooth muscle cell	16525	0.73	0.64	0.93	0.85	0.00	0.84	0.75	0.75	0.88
classical monocyte	16439	0.58	0.55	0.84	0.74	0.00	0.71	0.59	0.65	0.77
luminal epithelial cell of mammary gland	13905	0.98	0.00	0.98	0.85	0.00	0.96	0.98	0.96	0.99
capillary endothelial cell	13793	0.70	0.54	0.93	0.78	0.00	0.76	0.69	0.68	0.85
erythrocyte	13136	0.97	0.96	0.98	0.98	0.00	0.97	0.96	0.96	0.97
natural killer cell	12736	0.72	0.73	0.83	0.80	0.00	0.72	0.68	0.70	0.77
enterocyte of epithelium proper of duodenum	12144	0.91	0.00	0.88	0.75	0.00	0.94	0.91	0.89	0.96
stratified squamous epithelial cell	11080	0.84	0.72	0.93	0.83	0.00	0.83	0.85	0.82	0.90
acinar cell of salivary gland	11027	0.95	0.74	0.97	0.80	0.00	0.95	0.95	0.93	0.98
pulmonary alveolar type 2 cell	10382	0.97	0.96	0.99	0.89	0.00	0.96	0.97	0.96	0.98
conjunctival epithelial cell	9912	0.91	0.70	0.91	0.71	0.00	0.91	0.94	0.90	0.96
pericyte	9774	0.64	0.49	0.90	0.77	0.00	0.72	0.69	0.67	0.81
luminal cell of prostate epithelium	9586	0.91	0.68	0.96	0.86	0.00	0.93	0.94	0.92	0.95
cardiac endothelial cell	9147	0.94	0.80	0.98	0.83	0.00	0.97	0.95	0.88	0.98
naive thymus-derived CD4-positive, alpha-beta T cell	8856	0.21	0.02	0.51	0.32	0.00	0.28	0.24	0.30	0.39
kidney epithelial cell	8324	0.98	0.22	0.97	0.79	0.00	0.99	0.99	0.98	0.99
hepatocyte	6650	1.00	0.98	0.98	0.89	0.00	0.97	0.99	0.98	1.00
blood vessel smooth muscle cell	6012	0.73	0.20	0.95	0.87	0.00	0.94	0.90	0.79	0.95
enterocyte of epithelium proper of ileum	5837	0.97	0.00	0.86	0.67	0.00	0.96	0.98	0.96	0.98
T cell	5644	0.47	0.17	0.70	0.41	0.00	0.45	0.40	0.38	0.64
mast cell	5639	0.87	0.84	0.97	0.94	0.00	0.95	0.92	0.88	0.95
skeletal muscle satellite stem cell	5579	0.95	0.92	0.98	0.92	0.00	0.96	0.95	0.91	0.97
regular atrial cardiac myocyte	5261	0.82	0.62	0.91	0.75	0.00	0.96	0.91	0.91	0.95
pancreatic acinar cell	4921	0.95	0.01	0.97	0.83	0.00	0.91	0.98	0.96	0.99
intermediate monocyte	4943	0.38	0.10	0.71	0.53	0.00	0.27	0.38	0.46	0.57
mature NK T cell	4847	0.38	0.42	0.69	0.61	0.00	0.51	0.37	0.46	0.63
mononuclear phagocyte	4876	0.42	0.00	0.96	0.57	0.00	0.90	0.68	0.53	0.91
fibroblast of breast	4771	0.81	0.00	0.99	0.67	0.00	0.82	0.85	0.71	0.97
vascular associated smooth muscle cell	4541	0.68	0.02	0.86	0.67	0.00	0.76	0.65	0.65	0.79
vein endothelial cell	4236	0.42	0.09	0.87	0.60	0.00	0.55	0.50	0.49	0.72
CD4-positive, alpha-beta thymocyte	4228	0.39	0.00	0.75	0.58	0.00	0.67	0.38	0.35	0.72
enterocyte of epithelium of large intestine	4141	0.78	0.24	0.75	0.71	0.00	0.83	0.80	0.86	0.85
myofibroblast cell	4007	0.64	0.14	0.91	0.76	0.00	0.71	0.63	0.61	0.86
thymic fibroblast type 2	3766	0.58	0.00	0.86	0.52	0.00	0.86	0.67	0.56	0.90
corneal epithelial cell	3792	0.90	0.00	0.95	0.89	0.00	0.94	0.96	0.92	0.96
spermatid	3597	0.96	0.00	0.98	0.98	0.00	0.98	0.99	0.96	0.99
duct epithelial cell	3533	0.81	0.38	0.92	0.74	0.00	0.86	0.86	0.79	0.91
mesenchymal stem cell of adipose tissue	3433	0.28	0.00	0.75	0.58	0.00	0.48	0.32	0.37	0.55
basal cell of prostate epithelium	3145	0.73	0.01	0.93	0.77	0.00	0.83	0.88	0.75	0.88
endothelial cell of artery	3109	0.47	0.28	0.84	0.66	0.00	0.69	0.63	0.55	0.79
stromal cell	3118	0.61	0.01	0.70	0.58	0.00	0.89	0.79	0.70	0.93
thymic fibroblast type 1	2937	0.30	0.00	0.91	0.55	0.00	0.86	0.68	0.48	0.87
pulmonary alveolar type 1 cell	2802	0.96	0.93	0.98	0.93	0.00	0.95	0.98	0.94	0.98
spermatocyte	2772	0.92	0.00	0.97	0.93	0.00	0.96	0.98	0.96	0.98
pancreatic ductal cell	2448	0.89	0.13	0.95	0.83	0.00	0.87	0.96	0.94	0.97
regulatory T cell	2370	0.10	0.00	0.41	0.32	0.00	0.27	0.33	0.34	0.49
ventricular cardiac muscle cell	2358	0.30	0.00	0.81	0.67	0.00	0.96	0.83	0.84	0.88
endothelial cell of lymphatic vessel	2188	0.66	0.46	0.94	0.76	0.00	0.76	0.63	0.64	0.80
hematopoietic precursor cell	1919	0.63	0.65	0.84	0.78	0.00	0.46	0.60	0.61	0.78
retinal blood vessel endothelial cell	1866	0.23	0.00	0.92	0.47	0.00	0.96	0.63	0.54	0.91
small intestine goblet cell	1824	0.87	0.52	0.93	0.85	0.00	0.87	0.94	0.90	0.95
gamma-delta T cell	1809	0.20	0.11	0.78	0.38	0.00	0.56	0.67	0.49	0.79
fibroblast of cardiac tissue	1764	0.95	0.18	0.99	0.54	0.00	0.85	0.74	0.68	0.98
paneth cell of epithelium of small intestine	1675	0.48	0.41	0.79	0.58	0.00	0.68	0.69	0.74	0.83
club cell	1585	0.82	0.68	0.91	0.70	0.00	0.76	0.80	0.74	0.89
intestinal crypt stem cell of colon	1561	0.74	0.46	0.80	0.62	0.00	0.76	0.87	0.85	0.92
progenitor cell of mammary luminal epithelium	1520	0.98	0.00	0.99	0.97	0.00	0.94	0.96	0.93	0.99
epithelial cell	1502	0.90	0.29	0.98	0.73	0.00	0.90	0.92	0.92	0.95
basophil	1507	0.44	0.01	0.96	0.85	0.00	0.86	0.80	0.69	0.92
large intestine goblet cell	1415	0.88	0.15	0.93	0.77	0.00	0.77	0.94	0.89	0.94
eye photoreceptor cell	1385	0.90	0.90	0.96	0.94	0.00	0.96	0.98	0.97	0.97
epithelial cell of uterus	1267	0.93	0.23	0.98	0.65	0.00	0.90	0.92	0.86	0.98
enterocyte of epithelium proper of small intestine	1279	0.37	0.00	0.76	0.58	0.00	0.79	0.62	0.67	0.83
tissue-resident macrophage	1237	0.60	0.00	0.85	0.64	0.00	0.47	0.51	0.48	0.72
acinar cell	1204	0.82	0.31	0.97	0.88	0.00	0.89	0.92	0.89	0.93
non-classical monocyte	1148	0.35	0.30	0.55	0.37	0.00	0.24	0.35	0.37	0.60
lung ciliated cell	1078	0.74	0.14	0.98	0.91	0.00	0.97	0.95	0.92	0.98
activated CD8-positive, alpha-beta T cell	1038	0.38	0.00	0.87	0.45	0.00	0.58	0.33	0.32	0.71
alveolar adventitial fibroblast	1002	0.76	0.01	0.94	0.61	0.00	0.64	0.61	0.75	0.95
naive thymus-derived CD8-positive, alpha-beta T cell	938	0.14	0.00	0.61	0.40	0.00	0.19	0.18	0.14	0.45
adventitial cell	939	0.16	0.00	0.89	0.55	0.00	0.64	0.32	0.35	0.83
respiratory goblet cell	935	0.53	0.39	0.90	0.73	0.00	0.59	0.64	0.66	0.85
theca cell	937	0.66	0.00	0.87	0.74	0.00	0.62	0.79	0.61	0.89
myeloid leukocyte	909	0.14	0.00	0.84	0.45	0.00	0.68	0.31	0.21	0.77
keratocyte	896	0.36	0.00	0.77	0.31	0.00	0.53	0.54	0.39	0.78
enteroglial cell	901	0.83	0.53	0.97	0.91	0.00	0.83	0.91	0.81	0.89
erythroid progenitor cell	879	0.61	0.56	0.84	0.82	0.00	0.74	0.77	0.76	0.78
innate lymphoid cell	874	0.18	0.10	0.57	0.46	0.00	0.55	0.24	0.25	0.50
myometrial cell	831	0.82	0.00	0.88	0.67	0.00	0.79	0.68	0.62	0.89
endothelial cell of vascular tree	785	0.43	0.01	0.81	0.62	0.00	0.66	0.60	0.50	0.79
hematopoietic stem cell	767	0.71	0.52	0.85	0.80	0.00	0.74	0.87	0.83	0.87
salivary gland cell	762	0.55	0.00	0.92	0.72	0.00	0.81	0.56	0.63	0.91
granulocyte	693	0.23	0.00	0.70	0.66	0.00	0.23	0.28	0.22	0.58
CD8-positive, alpha-beta thymocyte	659	0.23	0.00	0.58	0.45	0.00	0.55	0.32	0.32	0.77
ciliated columnar cell of tracheobronchial tree	652	0.26	0.07	0.97	0.86	0.00	0.94	0.94	0.88	0.98
intrahepatic cholangiocyte	616	0.97	0.02	0.97	0.82	0.00	0.92	0.97	0.91	0.99
mural cell	545	0.32	0.07	0.95	0.62	0.00	0.65	0.65	0.57	0.96
intestinal crypt stem cell of small intestine	531	0.24	0.18	0.42	0.36	0.00	0.35	0.50	0.55	0.59
activated CD4-positive, alpha-beta T cell	495	0.04	0.00	0.55	0.30	0.00	0.16	0.14	0.13	0.32
myeloid dendritic cell	525	0.13	0.04	0.59	0.44	0.00	0.19	0.24	0.20	0.33
Mueller cell	459	0.64	0.30	0.84	0.79	0.00	0.86	0.95	0.83	0.91
fast muscle cell	443	0.69	0.49	0.94	0.87	0.00	0.92	0.80	0.89	0.94
platelet	457	0.90	0.89	0.96	0.93	0.00	0.78	0.94	0.78	0.96
myoepithelial cell	445	0.72	0.17	0.91	0.77	0.00	0.64	0.63	0.45	0.92
common myeloid progenitor	403	0.60	0.27	0.84	0.76	0.00	0.65	0.88	0.80	0.88
thymocyte	413	0.00	0.00	0.65	0.53	0.00	0.53	0.45	0.32	0.88
intestinal tuft cell	422	0.85	0.79	0.97	0.87	0.00	0.96	0.97	0.97	0.97
pancreatic stellate cell	393	0.00	0.00	0.97	0.63	0.00	0.62	0.57	0.40	0.87
tendon cell	385	0.63	0.01	0.74	0.54	0.00	0.42	0.55	0.33	0.81
microglial cell	369	0.09	0.00	0.75	0.27	0.00	0.50	0.25	0.19	0.57
muscle cell	359	0.72	0.00	0.98	0.94	0.00	0.92	0.75	0.94	0.96
enterocyte of epithelium proper of jejunum	353	0.00	0.00	0.65	0.56	0.00	0.93	0.56	0.40	0.93
mesothelial cell	316	0.61	0.47	0.94	0.83	0.00	0.61	0.50	0.74	0.78
colon endothelial cell	305	0.02	0.00	0.87	0.35	0.00	0.57	0.26	0.33	0.82
colon macrophage	293	0.20	0.00	0.83	0.46	0.00	0.80	0.30	0.27	0.88
serous cell of epithelium of trachea	299	0.40	0.00	0.87	0.65	0.00	0.34	0.49	0.55	0.84
ciliated epithelial cell	286	0.87	0.00	0.98	0.83	0.00	0.96	0.98	0.95	0.98
Schwann cell	290	0.71	0.32	0.87	0.72	0.00	0.56	0.79	0.75	0.85
supporting cell of vestibular epithelium	239	0.84	0.00	0.72	0.78	0.00	0.80	1.00	0.88	0.99
mucus secreting cell	246	0.52	0.02	0.89	0.74	0.00	0.72	0.70	0.74	0.88
enteroendocrine cell of small intestine	239	0.67	0.08	0.88	0.77	0.00	0.85	0.96	0.85	0.94
ovarian surface epithelial cell	222	0.43	0.07	0.93	0.87	0.00	0.62	0.84	0.70	0.96
transit amplifying cell of colon	214	0.50	0.17	0.66	0.48	0.00	0.35	0.75	0.67	0.86
glandular epithelial cell	209	0.58	0.03	0.91	0.67	0.00	0.88	0.96	0.72	0.99
melanocyte	210	0.65	0.30	0.86	0.66	0.00	0.75	0.85	0.75	0.92
tracheal goblet cell	212	0.00	0.14	0.87	0.70	0.00	0.70	0.83	0.69	0.94
hepatic stellate cell	197	0.36	0.00	0.83	0.40	0.00	0.51	0.54	0.36	0.73
bronchial smooth muscle cell	194	0.00	0.00	0.75	0.49	0.00	0.31	0.48	0.53	0.77
paneth cell of colon	196	0.44	0.07	0.76	0.62	0.00	0.47	0.81	0.37	0.90
tongue muscle cell	184	0.43	0.00	0.90	0.74	0.00	0.55	0.72	0.51	0.95
leukocyte	173	0.10	0.01	0.63	0.13	0.00	0.33	0.29	0.15	0.47
tuft cell of colon	146	0.00	0.03	0.88	0.60	0.00	0.83	0.90	0.90	0.98
slow muscle cell	155	0.70	0.15	0.87	0.77	0.00	0.58	0.91	0.91	0.95
ionocyte	147	0.58	0.05	0.82	0.64	0.00	0.34	0.86	0.80	0.93
connective tissue cell	132	0.01	0.00	0.97	0.82	0.00	0.37	0.47	0.25	0.94
neuro-medullary thymic epithelial cell	123	0.28	0.20	0.85	0.74	0.00	0.54	0.42	0.49	0.48
sebum secreting cell	117	0.00	0.02	0.93	0.48	0.00	0.65	0.94	0.64	0.93
endothelial cell of arteriole	121	0.00	0.00	0.94	0.32	0.00	0.72	0.52	0.49	0.98
male germ cell	104	0.00	0.00	0.90	0.83	0.00	0.79	1.00	0.78	0.99
type B pancreatic cell	92	0.81	0.00	0.94	0.86	0.00	0.92	1.00	0.96	0.99
hematopoietic cell	90	0.00	0.00	0.75	0.61	0.00	0.34	0.59	0.43	0.83
plasmacytoid dendritic cell	94	0.53	0.29	0.78	0.67	0.00	0.15	0.62	0.39	0.71
neuron	78	0.00	0.00	0.99	0.81	0.00	0.61	0.65	0.79	0.96
myeloid cell	76	0.00	0.00	0.66	0.03	0.00	0.29	0.34	0.28	0.74
myo-medullary thymic epithelial cell	74	0.68	0.00	0.95	0.85	0.00	0.91	0.90	0.94	0.96
Langerhans cell	66	0.00	0.00	0.85	0.54	0.00	0.24	0.39	0.42	0.87
interstitial cell of Cajal	64	0.00	0.00	0.95	0.72	0.00	0.61	0.58	0.60	0.94
retinal pigment epithelial cell	61	0.83	0.00	0.98	0.91	0.00	0.95	1.00	0.93	0.99
peritubular myoid cell	59	0.20	0.00	0.72	0.63	0.00	0.55	0.53	0.62	0.83
spermatogonium	54	0.00	0.00	0.74	0.57	0.00	0.56	0.94	0.80	0.89
retinal bipolar neuron	50	0.00	0.04	0.86	0.72	0.00	0.30	0.72	0.89	0.90
endothelial cell of venule	45	0.00	0.00	0.96	0.27	0.00	0.57	0.85	0.54	0.97
vestibular dark cell	44	0.00	0.00	0.45	0.23	0.00	0.34	1.00	0.93	0.96
pancreatic A cell	46	0.67	0.00	0.92	0.87	0.00	0.95	1.00	1.00	1.00
type L enteroendocrine cell	40	0.00	0.09	0.89	0.73	0.00	0.84	0.95	0.93	1.00
medullary thymic epithelial cell	40	0.00	0.00	0.75	0.26	0.00	0.40	0.94	0.73	0.92
adipocyte	37	0.00	0.00	0.69	0.48	0.00	0.55	0.69	0.46	0.88
transit amplifying cell of small intestine	34	0.00	0.00	0.40	0.33	0.00	0.14	0.83	0.75	0.91
taste receptor cell	29	0.00	0.00	0.82	0.47	0.00	0.09	0.84	0.27	0.89
enterochromaffin-like cell	25	0.00	0.01	0.83	0.59	0.00	0.85	1.00	0.89	0.96
enteroendocrine cell	21	0.00	0.00	0.91	0.73	0.00	0.72	0.93	0.84	0.93
pulmonary ionocyte	23	0.00	0.00	0.75	0.45	0.00	0.25	0.96	0.73	0.92
glial cell	19	0.00	0.00	0.75	0.62	0.00	0.25	0.76	0.30	0.64
oocyte	13	0.00	0.03	0.90	0.77	0.00	0.37	0.90	0.87	0.87
serous cell of epithelium of bronchus	15	0.00	0.00	0.93	0.12	0.00	0.14	0.71	0.94	1.00
radial glial cell	13	0.00	0.00	0.00	0.00	0.00	0.08	0.25	0.17	0.40
Leydig cell	7	0.00	0.00	0.17	0.22	0.00	0.20	0.16	0.45	0.88
pancreatic D cell	8	0.00	0.00	0.50	0.57	0.00	0.89	1.00	1.00	1.00
T follicular helper cell	5	0.00	0.00	0.00	0.00	0.00	0.02	0.62	0.42	0.89
retina horizontal cell	4	0.00	0.00	0.00	0.00	0.00	0.29	1.00	0.89	0.86
erythroid lineage cell	2	0.00	0.00	0.00	0.00	0.00	0.03	0.80	0.80	0.67
pancreatic PP cell	2	0.00	0.00	0.00	0.00	0.00	0.22	1.00	1.00	1.00
epithelial fate stem cell	1	0.00	0.00	0.00	0.00	0.00	0.12	0.06	0.50	1.00
mesenchymal cell	1	0.00	0.00	0.00	0.00	0.00	0.01	0.15	1.00	1.00

References

Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues, The Tabula Sapiens Consortium; bioRxiv, doi: https://doi.org/10.1101/2024.12.03.626516