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<|startoftext|><L>CCS(=O)(=O)[C@@](C)(Br)[C@@H](<mask_1:4>ccc1<mask_1:4>
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4
O)c1cc
4
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
O)c1
<|startoftext|><L>CCS(=O)(=O)[C<mask_1:4>)(Br)[C@@H](O)c1ccccc1<mask_1:4>
5
13
4
@@](C
4
CCS(=O)(=O)[C@](C)(Br)[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
@](C
<|startoftext|><L>C<mask_1:4>CS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1<mask_1:4>
0
1
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4
CC(C)CS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
C(C)
<|startoftext|><L>CCS(=O)(=O)[C@@](C)(Br)[C@@H<mask_1:1>c1ccccc1<mask_1:1>
4
28
1
](O)
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CCS(=O)(=O)[C@@](C)(Br)[C@@H]c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
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<|startoftext|><L>C<mask_1:1>CS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1<mask_1:1>
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CCCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
C
<|startoftext|><L>CCS(=O)(=O)[C@@](C)(Br)[C@@<mask_1:2>c1ccccc1<mask_1:2>
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27
2
H](O)
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CCS(=O)(=O)[C@@](C)(Br)[C@@H]c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
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<|startoftext|><L>CCS(=O)(=O)[C@@](C)(Br)[C@@H](O<mask_1:4>c1ccccc1<mask_1:4>
1
31
4
)
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CCS(=O)(=O)[C@@](C)(Br)[C@@H](OC)CCc1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
C)CC
<|startoftext|><L>CCS(=O)(=O)<mask_1:1>(C)(Br)[C@@H](O)c1ccccc1<mask_1:1>
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1
[C@@]
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CCS(=O)(=O)C(C)(Br)[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
C
<|startoftext|><L>CCS(=O)(=O)[C@@](C<mask_1:6>[C@@H](O)c1ccccc1<mask_1:6>
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6
)(Br)
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CCS(=O)(=O)[C@@](C)(Br)C[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
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<|startoftext|><L>CCS(=O)(=O)[C@@](C)(B<mask_1:6>r)[C@@H](O)c1ccccc1<mask_1:6>
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CCS(=O)(=O)[C@@](C)(Br)C(BBr)[C@@H](O)c1ccccc1
CCS(=O)(=O)[C@@](C)(Br)[C@@H](O)c1ccccc1
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<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN<mask_1:7>O)N(C)C)C1)C(C)C<mask_1:7>
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7
(S(=O)(=
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Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(CCCC(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
(CCCC(=
<|startoftext|><L>Cc1ccccc1[C@@H](NC<mask_1:5>)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:5>
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18
5
(=O
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Cc1ccccc1[C@@H](NC(C)(C)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
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<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@H<mask_1:7>CCN(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:7>
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26
7
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Cc1ccccc1[C@@H](NC(=O)[C@H](C)N1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
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<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[<mask_1:7>N(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:7>
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23
7
C@H]1CCC
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Cc1ccccc1[C@@H](NC(=O)[C@H]1CCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
C@H]1CC
<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C<mask_1:5>)C)C1)C(C)C<mask_1:5>
0
45
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Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)CC(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
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<|startoftext|><L>Cc1ccccc1[<mask_1:3>NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:3>
6
10
3
C@@H](
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Cc1ccccc1[C](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
C](
<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@<mask_1:4>CCCN(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:4>
3
25
4
H]1
4
Cc1ccccc1[C@@H](NC(=O)[C@@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
@H]1
<|startoftext|><L>Cc1ccccc1[C@@H](N<mask_1:8>[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C<mask_1:8>
5
17
8
C(=O)
9
Cc1ccccc1[C@@H](NS(=O)(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
S(=O)(=O)
<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(<mask_1:3>)N(C)C)C1)C(C)C<mask_1:3>
8
33
3
S(=O)(=O
3
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(C(C)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
C(C
<|startoftext|><L>Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN<mask_1:4>)(=O)N(C)C)C1)C(C)C<mask_1:4>
5
32
4
(S(=O
4
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(C)(=O)N(C)C)C1)C(C)C
Cc1ccccc1[C@@H](NC(=O)[C@H]1CCCN(S(=O)(=O)N(C)C)C1)C(C)C
(S(C
<|startoftext|><L>O=C(O)c1cc(Cl)c(Cl)c(C(F)(<mask_1:4>)c1<mask_1:4>
3
26
4
F)F
4
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)Cl)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
F)Cl
<|startoftext|><L>O=C(O)c1cc(<mask_1:4>)c(Cl)c(C(F)(F)F)c1<mask_1:4>
2
11
4
Cl
4
O=C(O)c1cc(NCCO)c(Cl)c(C(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
NCCO
<|startoftext|><L>O=C(O)c1cc(Cl)c(Cl)c(C(F)<mask_1:1>)c1<mask_1:1>
4
25
1
(F)F
1
O=C(O)c1cc(Cl)c(Cl)c(C(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
F
<|startoftext|><L>O=C(O)c1cc(Cl)c(C<mask_1:2>)c(C(F)(F)F)c1<mask_1:2>
1
17
2
l
2
O=C(O)c1cc(Cl)c(C=O)c(C(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
=O
<|startoftext|><L>O=C<mask_1:3>)c1cc(Cl)c(Cl)c(C(F)(F)F)c1<mask_1:3>
2
3
3
(O
3
O=C(NO)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
(NO
<|startoftext|><L>O=C(O)c1cc(<mask_1:2>(Cl)c(C(F)(F)F)c1<mask_1:2>
4
11
2
Cl)c
2
O=C(O)c1cc(F)(Cl)c(C(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
F)
<|startoftext|><L>O=C(O)c1cc(Cl)c(Cl)c<mask_1:3>C(F)(F)F)c1<mask_1:3>
1
20
3
(
3
O=C(O)c1cc(Cl)c(Cl)c(OCC(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
(OC
<|startoftext|><L>O=C(O)c1cc(Cl)c(Cl)c(C<mask_1:4>)(F)F)c1<mask_1:4>
2
22
4
(F
4
O=C(O)c1cc(Cl)c(Cl)c(COC(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
OC(F
<|startoftext|><L>O=C(O)c1cc(Cl)c(Cl)c(C(F)<mask_1:4>F)c1<mask_1:4>
3
25
4
(F)
4
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)CF)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
(F)C
<|startoftext|><L>O=C<mask_1:3>O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1<mask_1:3>
1
3
3
(
3
O=C(CCO)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
O=C(O)c1cc(Cl)c(Cl)c(C(F)(F)F)c1
(CC
<|startoftext|><L><mask_1:4>c1ccc(Cl)cc1CSC[C@@H](O)CO<mask_1:4>
2
0
4
CO
4
CCCCc1ccc(Cl)cc1CSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
CCCC
<|startoftext|><L>COc1<mask_1:4>cc(Cl)cc1CSC[C@@H](O)CO<mask_1:4>
1
4
4
c
4
COc1c(C)cc(Cl)cc1CSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
c(C)
<|startoftext|><L>COc1ccc(Cl)cc1<mask_1:2>CSC[C@@H](O)CO<mask_1:2>
0
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2
COc1ccc(Cl)cc1NCCSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
NC
<|startoftext|><L>COc1ccc(Cl)cc1CSC[C@<mask_1:2>O)CO<mask_1:2>
4
20
2
@H](
2
COc1ccc(Cl)cc1CSC[C@](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
](
<|startoftext|><L>COc1ccc(Cl)cc1CS<mask_1:2>@H](O)CO<mask_1:2>
4
16
2
C[C@
2
COc1ccc(Cl)cc1CS[C@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
[C
<|startoftext|><L>COc1ccc(Cl)cc1CSC[C@@<mask_1:3>)CO<mask_1:3>
4
21
3
H](O
3
COc1ccc(Cl)cc1CSC[C@@](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
](O
<|startoftext|><L>COc1ccc(C<mask_1:1>cc1CSC[C@@H](O)CO<mask_1:1>
2
9
1
l)
1
COc1ccc(C)cc1CSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
)
<|startoftext|><L>COc1ccc(C<mask_1:1>l)cc1CSC[C@@H](O)CO<mask_1:1>
0
9
1
1
COc1ccc(CCl)cc1CSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
C
<|startoftext|><L>COc1ccc(Cl)cc1CSC[C@@H](<mask_1:2>O<mask_1:2>
3
24
2
O)C
2
COc1ccc(Cl)cc1CSC[C@@H](C)O
COc1ccc(Cl)cc1CSC[C@@H](O)CO
C)
<|startoftext|><L>COc<mask_1:3>ccc(Cl)cc1CSC[C@@H](O)CO<mask_1:3>
1
3
3
1
3
COc1ncccc(Cl)cc1CSC[C@@H](O)CO
COc1ccc(Cl)cc1CSC[C@@H](O)CO
1nc
<|startoftext|><L>CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2<mask_1:2>CC2)n1<mask_1:2>
4
31
2
C2CC
2
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
C2
<|startoftext|><L>CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2<mask_1:5>CCCC2)n1<mask_1:5>
2
31
5
C2
5
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2CC2CCCCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
CC2CC
<|startoftext|><L>CCOC(=O)c1csc<mask_1:4>Sc2nc(=O)cc(O)n2C2CCCC2)n1<mask_1:4>
2
13
4
(C
4
CCOC(=O)c1csc(CCCSc2nc(=O)cc(O)n2C2CCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
(CCC
<|startoftext|><L>CCOC(=<mask_1:6>c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1<mask_1:6>
2
6
6
O)
6
CCOC(=O)/C=Cc1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
O)/C=C
<|startoftext|><L>CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2<mask_1:5>2)n1<mask_1:5>
6
31
5
C2CCCC
5
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2CC2CC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
CC2CC
<|startoftext|><L>CC<mask_1:6>OC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1<mask_1:6>
0
2
6
6
CC(C)(C)OC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
(C)(C)
<|startoftext|><L>CCOC(=O)c1csc<mask_1:5>CSc2nc(=O)cc(O)n2C2CCCC2)n1<mask_1:5>
1
13
5
(
5
CCOC(=O)c1csc(CNCCCSc2nc(=O)cc(O)n2C2CCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
(CNCC
<|startoftext|><L>CCOC(=O<mask_1:3>1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1<mask_1:3>
2
7
3
)c
3
CCOC(=O)Cc1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
)Cc
<|startoftext|><L>CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2<mask_1:5>CCCC2)n1<mask_1:5>
2
31
5
C2
5
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCCCCC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
C2CCC
<|startoftext|><L>CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CC<mask_1:5>C2)n1<mask_1:5>
1
35
5
C
5
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCC(C)CC2)n1
CCOC(=O)c1csc(CSc2nc(=O)cc(O)n2C2CCCC2)n1
C(C)C
<|startoftext|><L>CO<mask_1:3>1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:3>
1
2
3
c
3
COCCc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
CCc
<|startoftext|><L>COc1ccc(<mask_1:7>C(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:7>
2
8
7
CN
7
COc1ccc(CNC(=O)C(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
CNC(=O)
<|startoftext|><L>COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O<mask_1:1>C)cn2)cc1<mask_1:1>
5
39
1
)N(C)
1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
)
<|startoftext|><L>COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)<mask_1:1>C)C)cn2)cc1<mask_1:1>
6
36
1
(=O)N(
1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
(
<|startoftext|><L>COc1c<mask_1:5>CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:5>
3
5
5
cc(
5
COc1ccc(CCCNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
cc(CC
<|startoftext|><L>COc1ccc(CNC(=O)[C@<mask_1:3>C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:3>
4
18
3
@H](
3
COc1ccc(CNC(=O)[C@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
H](
<|startoftext|><L>CO<mask_1:7>1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:7>
1
2
7
c
7
COC(=O)Cc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
C(=O)Cc
<|startoftext|><L>COc1ccc(CNC(=O)<mask_1:2>[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:2>
0
15
2
2
COc1ccc(CNC(=O)NC[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
NC
<|startoftext|><L>COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)c<mask_1:2>cc1<mask_1:2>
3
47
2
n2)
3
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
n2)
<|startoftext|><L>COc1ccc(CNC(=O)[C@@H](C)<mask_1:4>c2ccc(S(=O)(=O)N(C)C)cn2)cc1<mask_1:4>
1
24
4
S
4
COc1ccc(CNC(=O)[C@@H](C)N(C)c2ccc(S(=O)(=O)N(C)C)cn2)cc1
COc1ccc(CNC(=O)[C@@H](C)Sc2ccc(S(=O)(=O)N(C)C)cn2)cc1
N(C)
<|startoftext|><L>COc1cccc([C@H]2[C@@H<mask_1:8>3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1<mask_1:8>
4
20
8
](Oc
8
COc1cccc([C@H]2[C@@H](C(=O)c3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
](C(=O)c
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2<mask_1:4>CCCN2CCOCC2)c1<mask_1:4>
1
41
4
C
4
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCNCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
CCCN
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN<mask_1:5>2CCOCC2)c1<mask_1:5>
0
46
5
5
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN(C)CN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
(C)CN
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3<mask_1:8>3Cl)C(=O)N2CCCCN2CCOCC2)c1<mask_1:8>
5
25
8
ccccc
8
COc1cccc([C@H]2[C@@H](Oc3ccc(F)cc3Cl)C(=O)N2CCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
ccc(F)cc
<|startoftext|><L>COc1<mask_1:7>[C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1<mask_1:7>
5
4
7
cccc(
7
COc1cccc(CC[C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
cccc(CC
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2C<mask_1:8>N2CCOCC2)c1<mask_1:8>
3
42
8
CCC
8
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCN(C)CCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
CCN(C)CC
<|startoftext|><L>COc1cccc([C@<mask_1:5>[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1<mask_1:5>
3
12
5
H]2
5
COc1cccc([C@@H]2C[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
@H]2C
<|startoftext|><L>COc1c<mask_1:6>([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1<mask_1:6>
3
5
6
ccc
6
COc1ccc(O)c([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
cc(O)c
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2C<mask_1:2>2)c1<mask_1:2>
4
48
2
COCC
2
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
CC
<|startoftext|><L>COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2<mask_1:2>COCC2)c1<mask_1:2>
7
41
2
CCCCN2C
2
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2C2COCC2)c1
COc1cccc([C@H]2[C@@H](Oc3ccccc3Cl)C(=O)N2CCCCN2CCOCC2)c1
C2
<|startoftext|><L>O=C(Nc1ccccc1)Nc1ccc2<mask_1:6>)C(=O)Nc1ccccc1O2<mask_1:6>
4
21
6
c(c1
6
O=C(Nc1ccccc1)Nc1ccc2c(c1Br)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
c(c1Br
<|startoftext|><L>O=C(Nc1ccccc1)Nc1cc<mask_1:4>2c(c1)C(=O)Nc1ccccc1O2<mask_1:4>
1
19
4
c
4
O=C(Nc1ccccc1)Nc1cc(F)c2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
(F)c
<|startoftext|><L>O=C(Nc1cccc<mask_1:3>c1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2<mask_1:3>
0
11
3
3
O=C(Nc1cccc(F)c1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
(F)
<|startoftext|><L>O=C(N<mask_1:5>c1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2<mask_1:5>
6
5
5
c1cccc
5
O=C(Nc1ccoc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
c1cco
<|startoftext|><L>O<mask_1:2>C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2<mask_1:2>
1
1
2
=
2
O=CC(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
=C
<|startoftext|><L>O=C(Nc1ccccc1)Nc1ccc2c(c1<mask_1:2>Nc1ccccc1O2<mask_1:2>
6
25
2
)C(=O)
2
O=C(Nc1ccccc1)Nc1ccc2c(c1)CNc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
)C
<|startoftext|><L>O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1c<mask_1:3>cccc1O2<mask_1:3>
0
35
3
3
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1c(F)cccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
(F)
<|startoftext|><L>O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)<mask_1:3>1ccccc1O2<mask_1:3>
2
31
3
Nc
3
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)NCc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
NCc
<|startoftext|><L>O=C(Nc<mask_1:2>ccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2<mask_1:2>
3
6
2
1cc
2
O=C(Nc1sccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
1s
<|startoftext|><L>O=C(<mask_1:3>cccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2<mask_1:3>
4
4
3
Nc1c
3
O=C(c1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
O=C(Nc1ccccc1)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2
c1c
<|startoftext|><L>Cc1nc2sc(<mask_1:7>=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:7>
2
9
7
C(
7
Cc1nc2sc(C(=O)C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
C(=O)C(
<|startoftext|><L>Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)<mask_1:1>1<mask_1:1>
4
45
1
[nH]
1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)o1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
o
<|startoftext|><L>Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[<mask_1:5>]1<mask_1:5>
2
46
5
nH
6
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH][nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
nH][nH
<|startoftext|><L>Cc1nc2sc(C<mask_1:5>3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:5>
6
10
5
(=O)Nc
5
Cc1nc2sc(C(=O)c3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
(=O)c
<|startoftext|><L>Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c<mask_1:4>=O)[nH]1<mask_1:4>
7
35
4
(C)c2c(
4
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)cc2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
c2c(
<|startoftext|><L>Cc1nc2sc(C(=O)Nc3cccc4c3ccn4<mask_1:5>C)c(C)c2c(=O)[nH]1<mask_1:5>
4
28
5
C(C)
5
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4CC(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
CC(C)
<|startoftext|><L>C<mask_1:5>c(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:5>
6
1
5
c1nc2s
5
Cc1nc2c(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
c1nc2
<|startoftext|><L>Cc1nc2sc<mask_1:5>(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:5>
2
8
5
(C
5
Cc1nc2sc(CCCC(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
(CCCC
<|startoftext|><L>Cc1nc<mask_1:5>c(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:5>
2
5
5
2s
5
Cc1nc2[nH]c(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
2[nH]
<|startoftext|><L><mask_1:4>nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1<mask_1:4>
3
0
4
Cc1
4
CCc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
Cc1nc2sc(C(=O)Nc3cccc4c3ccn4C(C)C)c(C)c2c(=O)[nH]1
CCc1
<|startoftext|><L>CCc1c(C(=O)N2CC<mask_1:4>CCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:4>
8
15
4
C3(CCCCO
4
CCc1c(C(=O)N2CCC(N3CCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
C(N3
<|startoftext|><L>CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc<mask_1:1>c12<mask_1:1>
4
58
1
(C)c
1
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccccc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
c
<|startoftext|><L>CCc1c(C(=O)N2CCC3(C<mask_1:5>OCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:5>
3
19
5
CCC
5
CCc1c(C(=O)N2CCC3(CC(=O)OCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
C(=O)
<|startoftext|><L>CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C<mask_1:8>C3=O)CC2)[nH]c2ccc(C)cc12<mask_1:8>
2
38
8
)N
8
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC(=O)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
)NC(=O)N
<|startoftext|><L>CCc1c(C(=O)N2CCC<mask_1:3>CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:3>
2
16
3
3(
3
CCc1c(C(=O)N2CCC3(CCCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
3(C
<|startoftext|><L>CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[<mask_1:7>C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:7>
5
32
7
C@H](
7
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@@H](CC)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
C@@H](C
<|startoftext|><L>CCc1c(C(=O)N2CCC3<mask_1:2>COCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:2>
4
17
2
(CCC
2
CCc1c(C(=O)N2CCC3(CCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
(C
<|startoftext|><L>CCc1c(C(=O<mask_1:3>N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:3>
1
10
3
)
3
CCc1c(C(=O)NCN2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
)NC
<|startoftext|><L>CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c<mask_1:4>cc12<mask_1:4>
7
54
4
2ccc(C)
4
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccccc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
2ccc
<|startoftext|><L>CCc1c(C(=O)N2CCC3(CCCCOCC<mask_1:7>[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12<mask_1:7>
6
25
7
NC(=O)
7
CCc1c(C(=O)N2CCC3(CCCCOCCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CCc1c(C(=O)N2CCC3(CCCCOCCNC(=O)[C@H](C)NC3=O)CC2)[nH]c2ccc(C)cc12
CNC(=O)