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<|startoftext|><L>CCc1sc2nc(SCc3nnnn3<mask_1:6>3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:6> | 4 | 19 | 6 | C3CC | 6 | CCc1sc2nc(SCc3nnnn3C3CCCC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | C3CCCC |
<|startoftext|><L>CCc1sc2nc(SCc3nnnn3C3CC3)n(<mask_1:1>Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:1> | 0 | 27 | 1 | 1 | CCc1sc2nc(SCc3nnnn3C3CC3)n(CCc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | C |
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<|startoftext|><L>CCc1sc2nc(S<mask_1:4>nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:4> | 3 | 11 | 4 | Cc3 | 4 | CCc1sc2nc(SCCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc3 |
<|startoftext|><L>CCc1sc2nc<mask_1:2>SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:2> | 1 | 9 | 2 | ( | 2 | CCc1sc2nc(CSCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | (C |
<|startoftext|><L>CCc1sc2nc(SCc3nnnn3C3<mask_1:3>3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:3> | 2 | 21 | 3 | CC | 3 | CCc1sc2nc(SCc3nnnn3C3CCC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCC |
<|startoftext|><L><mask_1:6>nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:6> | 7 | 0 | 6 | CCc1sc2 | 6 | Cc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | Cc1sc2 |
<|startoftext|><L>CCc1sc2<mask_1:3>Cc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:3> | 4 | 7 | 3 | nc(S | 3 | CCc1sc2nc(Cc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | nc( |
<|startoftext|><L>CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc<mask_1:4>)c(=O)c2c1C<mask_1:4> | 6 | 33 | 4 | (C)cc3 | 4 | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccccc3F)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | cc3F |
<|startoftext|><L><mask_1:6>CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:6> | 0 | 0 | 6 | 6 | CC(=O)CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CC(=O) |
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<|startoftext|><L>CCc1sc2nc(SCc3nnnn3<mask_1:7>C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C<mask_1:7> | 0 | 19 | 7 | 7 | CCc1sc2nc(SCc3nnnn3C(C)(C)C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | CCc1sc2nc(SCc3nnnn3C3CC3)n(Cc3ccc(C)cc3)c(=O)c2c1C | C(C)(C) |
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<|startoftext|><L>COc1cccc2c(C)c(C<mask_1:3>=O)Nc3c(C)nn(C(C)C)c3C)oc12<mask_1:3> | 1 | 16 | 3 | ( | 3 | COc1cccc2c(C)c(CCC(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | CC( |
<|startoftext|><L>COc1cccc2<mask_1:1>c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12<mask_1:1> | 4 | 9 | 1 | c(C) | 1 | COc1cccc2cc(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | c |
<|startoftext|><L>COc1cccc2c(C)c(C(=O)Nc3<mask_1:4>(C(C)C)c3C)oc12<mask_1:4> | 6 | 23 | 4 | c(C)nn | 4 | COc1cccc2c(C)c(C(=O)Nc3cccc(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | cccc |
<|startoftext|><L>COc1cccc2c(C)c(C(<mask_1:5>c(C)nn(C(C)C)c3C)oc12<mask_1:5> | 6 | 17 | 5 | =O)Nc3 | 5 | COc1cccc2c(C)c(C(=O)c3c(C)nn(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | =O)c3 |
<|startoftext|><L>COc1cccc2c(C)c(C(=O)Nc3c(C)nn<mask_1:1>C)c3C)oc12<mask_1:1> | 5 | 29 | 1 | (C(C) | 1 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | ( |
<|startoftext|><L>COc1cccc2c(C)c(C(=O)Nc3c(C)nn<mask_1:2>C)c3C)oc12<mask_1:2> | 5 | 29 | 2 | (C(C) | 2 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(CC)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | (C |
<|startoftext|><L>COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3<mask_1:5>)oc12<mask_1:5> | 1 | 38 | 5 | C | 5 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C(C)C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | C(C)C |
<|startoftext|><L>COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C<mask_1:6>(C)C)c3C)oc12<mask_1:6> | 0 | 31 | 6 | 6 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(CC(=O)N(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | C(=O)N |
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<|startoftext|><L>COc1cccc2c(C)c(<mask_1:6>)Nc3c(C)nn(C(C)C)c3C)oc12<mask_1:6> | 4 | 15 | 6 | C(=O | 6 | COc1cccc2c(C)c(CCC(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | CCC(=O |
<|startoftext|><L>COc1c<mask_1:6>cc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12<mask_1:6> | 1 | 5 | 6 | c | 6 | COc1cc(C=O)cc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | COc1cccc2c(C)c(C(=O)Nc3c(C)nn(C(C)C)c3C)oc12 | c(C=O) |
<|startoftext|><L>CC<mask_1:2>CN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:2> | 9 | 2 | 2 | OC(=O)C1C | 2 | CC1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | 1C |
<|startoftext|><L>CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3C<mask_1:7>(=O)NC3=O)C4)nn2)CC1<mask_1:7> | 2 | 46 | 7 | CC | 7 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CC(=O)NC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | C(=O)NC |
<|startoftext|><L>CCOC(=<mask_1:5>(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:5> | 7 | 6 | 5 | O)C1CCN | 5 | CCOC(=O)CC1(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | O)CC1 |
<|startoftext|><L>CCOC(=O)C1CCN(<mask_1:5>cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:5> | 3 | 14 | 5 | Cc2 | 5 | CCOC(=O)C1CCN(C=Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | C=Cc2 |
<|startoftext|><L>CCO<mask_1:2>(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:2> | 1 | 3 | 2 | C | 2 | CCONC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | NC |
<|startoftext|><L>CCOC(=O<mask_1:6>cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:6> | 10 | 7 | 6 | )C1CCN(Cc2 | 6 | CCOC(=O)C1(c2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | )C1(c2 |
<|startoftext|><L>CCO<mask_1:1>C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:1> | 5 | 3 | 1 | C(=O) | 1 | CCOCC1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | C |
<|startoftext|><L>CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c<mask_1:6>C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:6> | 10 | 30 | 6 | 3)C(=O)N([ | 6 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)CN([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | 3)CN([ |
<|startoftext|><L>CCOC(=O)C<mask_1:9>(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1<mask_1:9> | 4 | 9 | 9 | 1CCN | 9 | CCOC(=O)C1(C)CC(C)(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | 1(C)CC(C) |
<|startoftext|><L>CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2<mask_1:4>CC1<mask_1:4> | 1 | 64 | 4 | ) | 4 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC#CC1 | CCOC(=O)C1CCN(Cc2cn(-c3ccc4c(c3)C(=O)N([C@H]3CCC(=O)NC3=O)C4)nn2)CC1 | )CC# |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/C23CC<mask_1:2>CC(CC(C4)C2)C3)c1<mask_1:2> | 1 | 25 | 2 | 4 | 2 | Cc1cc(Br)c(O)c(/C=N/C23CC4CCC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | 4C |
<|startoftext|><L>Cc1cc(Br<mask_1:2>(/C=N/C23CC4CC(CC(C4)C2)C3)c1<mask_1:2> | 6 | 8 | 2 | )c(O)c | 2 | Cc1cc(Br)n(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | )n |
<|startoftext|><L>C<mask_1:6>Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1<mask_1:6> | 5 | 1 | 6 | c1cc( | 6 | COc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | Oc1cc( |
<|startoftext|><L>Cc1cc(<mask_1:2>c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1<mask_1:2> | 3 | 6 | 2 | Br) | 2 | Cc1cc(C)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | C) |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N<mask_1:4>C23CC4CC(CC(C4)C2)C3)c1<mask_1:4> | 1 | 19 | 4 | / | 4 | Cc1cc(Br)c(O)c(/C=N/NCCC23CC4CC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | /NCC |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/C23CC4CC(C<mask_1:6>C2)C3)c1<mask_1:6> | 5 | 30 | 6 | C(C4) | 6 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)CC2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | C(C4)C |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3<mask_1:6>c1<mask_1:6> | 1 | 40 | 6 | ) | 6 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c(=O)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | )c(=O) |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/<mask_1:4>C23CC4CC(CC(C4)C2)C3)c1<mask_1:4> | 0 | 20 | 4 | 4 | Cc1cc(Br)c(O)c(/C=N/N(C)C23CC4CC(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | N(C) |
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<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/C2<mask_1:4>(CC(C4)C2)C3)c1<mask_1:4> | 6 | 22 | 4 | 3CC4CC | 4 | Cc1cc(Br)c(O)c(/C=N/C23CC4(CC(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | 3CC4 |
<|startoftext|><L>Cc1cc(Br)c(O)c(/C=N/C23CC4CC(<mask_1:5>C(C4)C2)C3)c1<mask_1:5> | 1 | 29 | 5 | C | 5 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C)C(C4)C2)C3)c1 | Cc1cc(Br)c(O)c(/C=N/C23CC4CC(CC(C4)C2)C3)c1 | CC(C) |
<|startoftext|><L>Cc1cnn(<mask_1:3>C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1<mask_1:3> | 0 | 7 | 3 | 3 | Cc1cnn(CCOC[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | CCO |
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<|startoftext|><L>Cc1cnn(C[C@@H]2CN(c3cccc<mask_1:3>C#N)CCO2)c1<mask_1:3> | 5 | 24 | 3 | (F)c3 | 3 | Cc1cnn(C[C@@H]2CN(c3ccccc3CC#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | c3C |
<|startoftext|><L>Cc1cnn(C[C@@H]2CN(<mask_1:3>c(F)c3C#N)CCO2)c1<mask_1:3> | 5 | 18 | 3 | c3ccc | 3 | Cc1cnn(C[C@@H]2CN(C3sc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | C3s |
<|startoftext|><L>Cc1cnn(C[C@@H]2CN(<mask_1:5>cccc(F)c3C#N)CCO2)c1<mask_1:5> | 2 | 18 | 5 | c3 | 5 | Cc1cnn(C[C@@H]2CN(CCOc3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | CCOc3 |
<|startoftext|><L>Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C<mask_1:2>2)c1<mask_1:2> | 6 | 30 | 2 | #N)CCO | 2 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C)C2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | )C |
<|startoftext|><L>Cc1cnn(C[C@@H]2C<mask_1:1>c3cccc(F)c3C#N)CCO2)c1<mask_1:1> | 2 | 16 | 1 | N( | 1 | Cc1cnn(C[C@@H]2C(c3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | ( |
<|startoftext|><L>Cc1cnn(C[C@@H]<mask_1:2>CN(c3cccc(F)c3C#N)CCO2)c1<mask_1:2> | 1 | 14 | 2 | 2 | 2 | Cc1cnn(C[C@@H]2CCN(c3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | 2C |
<|startoftext|><L>Cc1cnn(C[<mask_1:1>H]2CN(c3cccc(F)c3C#N)CCO2)c1<mask_1:1> | 3 | 9 | 1 | C@@ | 1 | Cc1cnn(C[CH]2CN(c3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | C |
<|startoftext|><L>C<mask_1:3>cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1<mask_1:3> | 2 | 1 | 3 | c1 | 3 | CCc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | Cc1 |
<|startoftext|><L>Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)<mask_1:6>CO2)c1<mask_1:6> | 1 | 33 | 6 | C | 6 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)C(=O)CCO2)c1 | Cc1cnn(C[C@@H]2CN(c3cccc(F)c3C#N)CCO2)c1 | C(=O)C |
<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN<mask_1:5>O)c2cc3ccccn3c2)CC1<mask_1:5> | 4 | 20 | 5 | (C(= | 5 | Cc1ccccc1C(=O)NC1CCN(CC(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | (CC(= |
<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN(C(=O)c<mask_1:5>ccn3c2)CC1<mask_1:5> | 6 | 27 | 5 | 2cc3cc | 5 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3sccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | 2cc3s |
<|startoftext|><L>Cc1ccc<mask_1:3>cc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1<mask_1:3> | 0 | 6 | 3 | 3 | Cc1ccc(F)cc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | (F) |
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<|startoftext|><L>Cc1ccccc1C(=O)NC1<mask_1:1>CCN(C(=O)c2cc3ccccn3c2)CC1<mask_1:1> | 0 | 17 | 1 | 1 | Cc1ccccc1C(=O)NC1CCCN(C(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | C |
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<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN(C(=<mask_1:6>O)c2cc3ccccn3c2)CC1<mask_1:6> | 0 | 24 | 6 | 6 | Cc1ccccc1C(=O)NC1CCN(C(=O)CC(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | O)CC(= |
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<|startoftext|><L>Cc1ccccc1C(=O)<mask_1:6>NC1CCN(C(=O)c2cc3ccccn3c2)CC1<mask_1:6> | 0 | 14 | 6 | 6 | Cc1ccccc1C(=O)NC(=S)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | NC(=S) |
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<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc<mask_1:6>ccn3c2)CC1<mask_1:6> | 3 | 30 | 6 | 3cc | 6 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3cc(F)ccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | 3cc(F) |
<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN(C(=<mask_1:5>2cc3ccccn3c2)CC1<mask_1:5> | 3 | 24 | 5 | O)c | 5 | Cc1ccccc1C(=O)NC1CCN(C(=O)COc2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | O)COc |
<|startoftext|><L>Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3cc<mask_1:6>2)CC1<mask_1:6> | 5 | 33 | 6 | ccn3c | 6 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccc3nc2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | ccc3nc |
<|startoftext|><L>Cc1ccccc1C(=O)NC1CC<mask_1:6>O)c2cc3ccccn3c2)CC1<mask_1:6> | 5 | 19 | 6 | N(C(= | 6 | Cc1ccccc1C(=O)NC1CCC(NC(=O)c2cc3ccccn3c2)CC1 | Cc1ccccc1C(=O)NC1CCN(C(=O)c2cc3ccccn3c2)CC1 | C(NC(= |
<|startoftext|><L>O=C(COc1ccc(<mask_1:5>=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:5> | 2 | 12 | 5 | S( | 5 | O=C(COc1ccc(CCNS(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | CCNS( |
<|startoftext|><L>O=C(COc1ccc(S<mask_1:4>)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:4> | 7 | 13 | 4 | (=O)(=O | 4 | O=C(COc1ccc(SC(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | C(=O |
<|startoftext|><L>O=C(CO<mask_1:2>c(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:2> | 4 | 6 | 2 | c1cc | 2 | O=C(COc1c(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | c1 |
<|startoftext|><L>O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCC<mask_1:2>2ccccc21<mask_1:2> | 1 | 44 | 2 | c | 2 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | Cc |
<|startoftext|><L>O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H<mask_1:6>CCc2ccccc21<mask_1:6> | 3 | 39 | 6 | ]1C | 6 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCCCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | ]1CCCC |
<|startoftext|><L>O=C(C<mask_1:4>Oc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:4> | 0 | 5 | 4 | 4 | O=C(CCCCCOc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | CCCC |
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<|startoftext|><L>O=C(COc1ccc(S(=O)(=O)N<mask_1:3>2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:3> | 0 | 22 | 3 | 3 | O=C(COc1ccc(S(=O)(=O)NCCN2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | CCN |
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<|startoftext|><L>O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CC<mask_1:5>Cc2ccccc21<mask_1:5> | 0 | 43 | 5 | 5 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CC(=O)NCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | (=O)N |
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<|startoftext|><L>O=C(COc1ccc<mask_1:6>=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21<mask_1:6> | 7 | 11 | 6 | (S(=O)( | 6 | O=C(COc1ccc(CCCC(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | (CCCC( |
<|startoftext|><L>O=C(COc1ccc(S(=O)(=O<mask_1:6>C2)cc1)N[C@H]1CCCc2ccccc21<mask_1:6> | 7 | 20 | 6 | )N2CCOC | 6 | O=C(COc1ccc(S(=O)(=O)N2CCCC2)cc1)N[C@H]1CCCc2ccccc21 | O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1)N[C@H]1CCCc2ccccc21 | )N2CCC |
<|startoftext|><L>O=C(CSCc1nc2scc(-c3cc<mask_1:1>c3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:1> | 6 | 21 | 1 | c(Cl)c | 1 | O=C(CSCc1nc2scc(-c3ccsc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | s |
<|startoftext|><L>O=C(CSCc1nc2scc(-c<mask_1:5>(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:5> | 4 | 18 | 5 | 3ccc | 4 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | 3ccc |
<|startoftext|><L><mask_1:6>C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:6> | 2 | 0 | 6 | O= | 6 | O=C(O)C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(O) |
<|startoftext|><L>O=C(CSCc1nc2scc(-c3ccc(<mask_1:6>3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:6> | 5 | 23 | 6 | Cl)cc | 6 | O=C(CSCc1nc2scc(-c3ccc(C=O)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | C=O)cc |
<|startoftext|><L>O=C<mask_1:2>Cc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:2> | 3 | 3 | 2 | (CS | 2 | O=C(CCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | (C |
<|startoftext|><L>O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c<mask_1:7>O)[nH]1)N1CCCCCC1<mask_1:7> | 2 | 33 | 7 | (= | 7 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | (=O)c(= |
<|startoftext|><L>O=C(CSCc1<mask_1:7>2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:7> | 2 | 9 | 7 | nc | 7 | O=C(CSCc1nc(=O)c2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | nc(=O)c |
<|startoftext|><L>O=C<mask_1:3>SCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:3> | 2 | 3 | 3 | (C | 3 | O=C(CCSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | (CC |
<|startoftext|><L>O=C(CSCc1nc2scc(-c3ccc(Cl<mask_1:5>)c2c(=O)[nH]1)N1CCCCCC1<mask_1:5> | 4 | 25 | 5 | )cc3 | 6 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3Cl)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | )cc3Cl |
<|startoftext|><L>O=C(CSCc1nc2scc(-c3ccc(<mask_1:4>3)c2c(=O)[nH]1)N1CCCCCC1<mask_1:4> | 5 | 23 | 4 | Cl)cc | 4 | O=C(CSCc1nc2scc(-c3ccc(F)cc3)c2c(=O)[nH]1)N1CCCCCC1 | O=C(CSCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1)N1CCCCCC1 | F)cc |
<|startoftext|><L>O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n<mask_1:4>CC1<mask_1:4> | 2 | 38 | 4 | 2) | 4 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CCCC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | 2)CC |
<|startoftext|><L>O=C(C1CCC<mask_1:4>C1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1<mask_1:4> | 0 | 9 | 4 | 4 | O=C(C1CCC(O)CC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | (O)C |
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<|startoftext|><L>O=C(C1<mask_1:6>CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1<mask_1:6> | 0 | 6 | 6 | 6 | O=C(C1(O)CCCCCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | (O)CCC |
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<|startoftext|><L>O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)<mask_1:2>CC1<mask_1:2> | 3 | 37 | 2 | n2) | 3 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | n2) |
<|startoftext|><L>O=C(C1CCCC1)N1CCC(c2cncc(<mask_1:4>[nH]3)n2)CC1<mask_1:4> | 6 | 25 | 4 | -c3ncc | 4 | O=C(C1CCCC1)N1CCC(c2cncc(-c3n[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | -c3n |
<|startoftext|><L>O=C(C1CCC<mask_1:6>1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1<mask_1:6> | 1 | 9 | 6 | C | 6 | O=C(C1CCC(O)CCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | (O)CCC |
<|startoftext|><L>O=C(C1CCCC1)N1CCC(<mask_1:4>cncc(-c3ncc[nH]3)n2)CC1<mask_1:4> | 2 | 18 | 4 | c2 | 4 | O=C(C1CCCC1)N1CCC(COc2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | COc2 |
<|startoftext|><L>O=C(C1C<mask_1:4>CC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1<mask_1:4> | 1 | 7 | 4 | C | 4 | O=C(C1CC(O)CC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | C(O) |
<|startoftext|><L>O=C(C1CCC<mask_1:3>1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1<mask_1:3> | 1 | 9 | 3 | C | 3 | O=C(C1CCCCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | CCC |
<|startoftext|><L>O=C(C1CCCC1)N1CCC(<mask_1:4>c(-c3ncc[nH]3)n2)CC1<mask_1:4> | 5 | 18 | 4 | c2cnc | 4 | O=C(C1CCCC1)N1CCC(c2noc(-c3ncc[nH]3)n2)CC1 | O=C(C1CCCC1)N1CCC(c2cncc(-c3ncc[nH]3)n2)CC1 | c2no |
<|startoftext|><L>CCc<mask_1:5>1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O<mask_1:5> | 6 | 3 | 5 | 1ccccc | 5 | CCc1nnsc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | 1nnsc |
<|startoftext|><L>CCc1ccccc1N(CC(=O)N[C@@H](C<mask_1:5>S(C)(=O)=O<mask_1:5> | 4 | 27 | 5 | )CC) | 5 | CCc1ccccc1N(CC(=O)N[C@@H](C)COC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | )COC) |
<|startoftext|><L>CCc1ccccc1N(C<mask_1:5>[C@@H](C)CC)S(C)(=O)=O<mask_1:5> | 6 | 13 | 5 | C(=O)N | 5 | CCc1ccccc1N(C(=O)N[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | (=O)N |
<|startoftext|><L>CCc1ccccc1<mask_1:6>C(=O)N[C@@H](C)CC)S(C)(=O)=O<mask_1:6> | 3 | 10 | 6 | N(C | 6 | CCc1ccccc1N(CCCCC(=O)N[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | N(CCCC |
<|startoftext|><L>CCc1cc<mask_1:5>c1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O<mask_1:5> | 2 | 6 | 5 | cc | 5 | CCc1cccc(C)c1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | cc(C) |
<|startoftext|><L>CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C<mask_1:6>=O<mask_1:6> | 5 | 34 | 6 | )(=O) | 6 | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)N=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | )(=O)N |
<|startoftext|><L>CCc1ccccc1N(CC(=O)N[C@@H](C<mask_1:4>C)S(C)(=O)=O<mask_1:4> | 2 | 27 | 4 | )C | 4 | CCc1ccccc1N(CC(=O)N[C@@H](C)CCCC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | )CCC |
<|startoftext|><L>CCc1ccccc1N(C<mask_1:5>[C@@H](C)CC)S(C)(=O)=O<mask_1:5> | 6 | 13 | 5 | C(=O)N | 5 | CCc1ccccc1N(C(=O)C[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | (=O)C |
<|startoftext|><L>CCc1ccccc1N(CC(=O)N[C@@H](<mask_1:3>CC)S(C)(=O)=O<mask_1:3> | 2 | 26 | 3 | C) | 3 | CCc1ccccc1N(CC(=O)N[C@@H](CC)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | CC) |
<|startoftext|><L>CCc1ccccc1N(C<mask_1:2>C(=O)N[C@@H](C)CC)S(C)(=O)=O<mask_1:2> | 0 | 13 | 2 | 2 | CCc1ccccc1N(CCCC(=O)N[C@@H](C)CC)S(C)(=O)=O | CCc1ccccc1N(CC(=O)N[C@@H](C)CC)S(C)(=O)=O | CC |