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Please translate the following sentences from Chinese to English.
唯物史观的科学性与价值性--晚年恩格斯的新思考
On scientificalness and value nature of historical materialism
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On scientificalness and value nature of historical materialism
唯物史观的科学性与价值性--晚年恩格斯的新思考
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形式的背后:两宋劝农制度的历史分析
Behind the Form:A Historical Analysis on the Quannong System of the Song Dynasty
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Behind the Form:A Historical Analysis on the Quannong System of the Song Dynasty
形式的背后:两宋劝农制度的历史分析
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论唐传奇在中国文学史上的演进与贡献
The Evolution and Contribution of the Legends of the Tang Dynasty in the History of Chinese Literature
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The Evolution and Contribution of the Legends of the Tang Dynasty in the History of Chinese Literature
论唐传奇在中国文学史上的演进与贡献
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国医大师张学文治疗原发性嗜睡的思路与方法
Treatment Thinking and Method of Chinese Medicine Master ZHANG Xue-wen on Primary Somnolence
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Treatment Thinking and Method of Chinese Medicine Master ZHANG Xue-wen on Primary Somnolence
国医大师张学文治疗原发性嗜睡的思路与方法
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中医治疗胆汁反流性胃炎研究述略
Review About the Research of Traditional Chinese Medicine on Bile Reflux Gastritis
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Review About the Research of Traditional Chinese Medicine on Bile Reflux Gastritis
中医治疗胆汁反流性胃炎研究述略
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血清蛋白质β-折叠水平与冠心病的相关性
Association between serum β-sheet level and coronary heart disease
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Association between serum β-sheet level and coronary heart disease
血清蛋白质β-折叠水平与冠心病的相关性
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复杂地层钻孔灌注桩后注浆施工技术应用研究。钻孔灌注桩因其施工容易、对地层适应性强和造价经济等优点,在各类建筑工程中应用广泛.以济南地铁位里庄车辆段桩基工程为案例基础,对于北方城市普遍存在的特殊软弱地质土层,做好桩端桩侧后注浆工艺质量控制措施,经后注浆与普通未注浆桩基试验应用效果数据对比得出,采用桩基注浆施工技术,可充分消除桩底砂土液化,使桩侧摩阻力形成一个结石体来抵消地下水位变化引起的桩侧负摩阻力影响,很好地解决了黄河冲积平原地区地质地层复杂持力层较差、受地下水丰富影响较大区域钻孔灌注桩单桩承载力远低于设计预估值的技术难题,为今后类似工程施工建设提供借鉴.
Application of Post Grouting Construction Technology for Drilling and Grouting Piles in Complex Geological Formations. Drilled cast-in-place piles are widely used in various construction projects due to their advantages such as easy construction,strong adaptability to strata,and economic cost.Based on the pile foundation project of Weilizhuang Depot of Jinan Metro as a case study,for the special weak geological soil layer commonly found in northern cities,quality control measures for post grouting technology at the pile end and side were taken.After comparing the application effect data of post grouting and ordinary non grouting pile foundation tests,it was found that using pile foundation grouting construction technology can fully eliminate liquefaction of sand soil at the pile bottom,The formation of a stone body to counteract the negative frictional resistance on the pile side caused by changes in groundwater level effectively solves the technical problem of the complex geological strata and poor bearing layer in the Yellow River alluvial plain,as well as the fact that the single pile bearing capacity of bored piles in areas greatly affected by groundwater abundance is far lower than the design estimate.This provides a reference for similar engineering construction in the future.
Please translate the following sentences from English to Chinese.
Application of Post Grouting Construction Technology for Drilling and Grouting Piles in Complex Geological Formations. Drilled cast-in-place piles are widely used in various construction projects due to their advantages such as easy construction,strong adaptability to strata,and economic cost.Based on the pile foundation project of Weilizhuang Depot of Jinan Metro as a case study,for the special weak geological soil layer commonly found in northern cities,quality control measures for post grouting technology at the pile end and side were taken.After comparing the application effect data of post grouting and ordinary non grouting pile foundation tests,it was found that using pile foundation grouting construction technology can fully eliminate liquefaction of sand soil at the pile bottom,The formation of a stone body to counteract the negative frictional resistance on the pile side caused by changes in groundwater level effectively solves the technical problem of the complex geological strata and poor bearing layer in the Yellow River alluvial plain,as well as the fact that the single pile bearing capacity of bored piles in areas greatly affected by groundwater abundance is far lower than the design estimate.This provides a reference for similar engineering construction in the future.
复杂地层钻孔灌注桩后注浆施工技术应用研究。钻孔灌注桩因其施工容易、对地层适应性强和造价经济等优点,在各类建筑工程中应用广泛.以济南地铁位里庄车辆段桩基工程为案例基础,对于北方城市普遍存在的特殊软弱地质土层,做好桩端桩侧后注浆工艺质量控制措施,经后注浆与普通未注浆桩基试验应用效果数据对比得出,采用桩基注浆施工技术,可充分消除桩底砂土液化,使桩侧摩阻力形成一个结石体来抵消地下水位变化引起的桩侧负摩阻力影响,很好地解决了黄河冲积平原地区地质地层复杂持力层较差、受地下水丰富影响较大区域钻孔灌注桩单桩承载力远低于设计预估值的技术难题,为今后类似工程施工建设提供借鉴.
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低成本下基坑水平支撑拆除方式研究
Study on Demolition of Foundation Pit Level Support under the Low Cost
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Study on Demolition of Foundation Pit Level Support under the Low Cost
低成本下基坑水平支撑拆除方式研究
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基于BDS的桥梁形变监测系统实现
Implementation of Deformation Monitoring System About Bridge Based on BDS
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Implementation of Deformation Monitoring System About Bridge Based on BDS
基于BDS的桥梁形变监测系统实现
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预防性颈中央区淋巴结清除术治疗甲状腺乳头状癌安全性的meta分析
Meta-analysis of the security of thyroidectomy combined with prophylactic central neck dissection
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Meta-analysis of the security of thyroidectomy combined with prophylactic central neck dissection
预防性颈中央区淋巴结清除术治疗甲状腺乳头状癌安全性的meta分析
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非低阶煤煤层气解吸关系研究
Experimental Study of Coalbed Methane Desorption Formula of Non-Low Rank Coal
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Experimental Study of Coalbed Methane Desorption Formula of Non-Low Rank Coal
非低阶煤煤层气解吸关系研究
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采油集输系统腐蚀防护技术研究
Research on Corrosion Protection Technologies for Oil Gathering and Distribution System
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Research on Corrosion Protection Technologies for Oil Gathering and Distribution System
采油集输系统腐蚀防护技术研究
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关于货币政策有效性的实证研究
An Empirical Study of the Effectiveness of Monetary Policy
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An Empirical Study of the Effectiveness of Monetary Policy
关于货币政策有效性的实证研究
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免疫亲和柱净化、高效液相色谱法结合荧光检测器检测进出口芝麻中的黄曲霉毒素B1
Immunoaffinity chromatogaphy together with the HPLC to test aflatoxin B1 among imported sesame
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Immunoaffinity chromatogaphy together with the HPLC to test aflatoxin B1 among imported sesame
免疫亲和柱净化、高效液相色谱法结合荧光检测器检测进出口芝麻中的黄曲霉毒素B1
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新中国青年突击运动发生史探赜
On the History of the Youth Shock Movement in New China
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On the History of the Youth Shock Movement in New China
新中国青年突击运动发生史探赜
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滇西乌头中三种二萜生物碱相关药效和毒性的对比。目的 对滇西乌头中分离的二萜生物碱草乌甲素、黑乌弱碱和滇乌碱抗炎镇痛活性和急性毒性进行比较研究.方法 灌胃给药后,通过小鼠醋酸扭体和二甲苯耳肿胀实验,考察3种生物碱的抗炎镇痛效果,并比较3者的急性毒性.结果 (1)草乌甲素、滇乌碱和黑乌弱碱的LD50分别为:4.06 mg/kg、2.81 mg/kg、12.00mg/kg;(2)3种生物碱单次灌胃给药,对醋酸致小鼠扭体性疼痛均有不同程度的抑制作用,2.0 mg/kg的草乌甲素作用最强,抑制率高于相同剂量的滇乌碱和黑乌弱碱,与同剂量的黑乌弱碱组比较,有统计学意义(P<0.05);(3)草乌甲素、滇乌碱对二甲苯致耳廓肿胀有明显抑制作用,与溶媒组比较有统计学意义(P<0.05),同等剂量的黑乌弱碱抗炎作用不明显;0.4 mg/kg滇乌碱抗炎作用最强,与同剂量的草乌甲素和黑乌弱碱组比较有统计学意义(P<0.01).结论 (1)急性毒性比较:滇乌碱>草乌甲素>黑乌弱碱;(2)3种生物碱都有不同程度的镇痛作用,草乌甲素镇痛作用最强;(3)滇乌碱抗炎作用优于同浓度的草乌甲素和黑乌弱碱.
Comparation of Three Kinds of Diterpenoid Alkaloid from Aconitum bulleyanum Diels in Related Pharmacodynamics and Toxicity. Objective To investigate the anti-inflammatory and analgesic activity and acute toxicity of Bulleyaconitine A and Foresaconitine and Yunaconitine from Aconitum bulleyanum Diels.Methods After intragastric administration,the anti-inflammatory and analgesic activities of Bulleyaconitine A and Foresaconitine and Yunaconitine using Acetic acid writhing test and Dimethylbenzene auricle swelling test in mice were compared.The acute toxicities of three iterpenoidalkaloids were also compared according to LD50.Results (1) The LD50 values of Bulleyaconitine A and Foresaconitine and Yunaconitine were:4.06 mg/kg,2.81 mg/kg and 12 mg/kg;(2) Single intragastric administration of three kinds of alkaloids all had obvious inhibitory effect on acetic acid-induced writhing pain.The 2 mg/kg group of Bulleyaconitine A bad the strongest effect,the inhibition rate was higher than the same dose of Foresaconitine and Yunaconitine,there was significant difference compared with Foresaconitine group (P<0.05);(3) Bulleyaconitine A and Yunaconitine had obvious inhibiting effect on auricle swelling induced by dimethylbenzene,there were significant differences compared with the vehicle group (P < 0.05),Foresaconitine with the same dose had no obvious effect;0.4 mg/kg Yunaconitine had the strongest anti-inflammatory effects,there were significant differences compared with the same dose of Bulleyaconitine A and Foresaconitine groups (P <0.01).Conclusion (1) Comparison of acute toxicity:Yunaconitine > Bulleyaconitine A >Foresaconitine;(2) Three alkaloids all have analgesic effects in different degree,Bulleyaconitine A is the strongest;(3) Yunaconitine is better than Bulleyaconitine A and Foresaconitine in anti-inflammatory effect with same concentration.
Please translate the following sentences from English to Chinese.
Comparation of Three Kinds of Diterpenoid Alkaloid from Aconitum bulleyanum Diels in Related Pharmacodynamics and Toxicity. Objective To investigate the anti-inflammatory and analgesic activity and acute toxicity of Bulleyaconitine A and Foresaconitine and Yunaconitine from Aconitum bulleyanum Diels.Methods After intragastric administration,the anti-inflammatory and analgesic activities of Bulleyaconitine A and Foresaconitine and Yunaconitine using Acetic acid writhing test and Dimethylbenzene auricle swelling test in mice were compared.The acute toxicities of three iterpenoidalkaloids were also compared according to LD50.Results (1) The LD50 values of Bulleyaconitine A and Foresaconitine and Yunaconitine were:4.06 mg/kg,2.81 mg/kg and 12 mg/kg;(2) Single intragastric administration of three kinds of alkaloids all had obvious inhibitory effect on acetic acid-induced writhing pain.The 2 mg/kg group of Bulleyaconitine A bad the strongest effect,the inhibition rate was higher than the same dose of Foresaconitine and Yunaconitine,there was significant difference compared with Foresaconitine group (P<0.05);(3) Bulleyaconitine A and Yunaconitine had obvious inhibiting effect on auricle swelling induced by dimethylbenzene,there were significant differences compared with the vehicle group (P < 0.05),Foresaconitine with the same dose had no obvious effect;0.4 mg/kg Yunaconitine had the strongest anti-inflammatory effects,there were significant differences compared with the same dose of Bulleyaconitine A and Foresaconitine groups (P <0.01).Conclusion (1) Comparison of acute toxicity:Yunaconitine > Bulleyaconitine A >Foresaconitine;(2) Three alkaloids all have analgesic effects in different degree,Bulleyaconitine A is the strongest;(3) Yunaconitine is better than Bulleyaconitine A and Foresaconitine in anti-inflammatory effect with same concentration.
滇西乌头中三种二萜生物碱相关药效和毒性的对比。目的 对滇西乌头中分离的二萜生物碱草乌甲素、黑乌弱碱和滇乌碱抗炎镇痛活性和急性毒性进行比较研究.方法 灌胃给药后,通过小鼠醋酸扭体和二甲苯耳肿胀实验,考察3种生物碱的抗炎镇痛效果,并比较3者的急性毒性.结果 (1)草乌甲素、滇乌碱和黑乌弱碱的LD50分别为:4.06 mg/kg、2.81 mg/kg、12.00mg/kg;(2)3种生物碱单次灌胃给药,对醋酸致小鼠扭体性疼痛均有不同程度的抑制作用,2.0 mg/kg的草乌甲素作用最强,抑制率高于相同剂量的滇乌碱和黑乌弱碱,与同剂量的黑乌弱碱组比较,有统计学意义(P<0.05);(3)草乌甲素、滇乌碱对二甲苯致耳廓肿胀有明显抑制作用,与溶媒组比较有统计学意义(P<0.05),同等剂量的黑乌弱碱抗炎作用不明显;0.4 mg/kg滇乌碱抗炎作用最强,与同剂量的草乌甲素和黑乌弱碱组比较有统计学意义(P<0.01).结论 (1)急性毒性比较:滇乌碱>草乌甲素>黑乌弱碱;(2)3种生物碱都有不同程度的镇痛作用,草乌甲素镇痛作用最强;(3)滇乌碱抗炎作用优于同浓度的草乌甲素和黑乌弱碱.
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数据挖掘与数据库知识发掘
Data Mining and Knowledge Discovery in Databases
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Data Mining and Knowledge Discovery in Databases
数据挖掘与数据库知识发掘
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合金成分与挤压工艺对6005A车体型材性能的影响研究
Study on Influence of Chemical Compositions and Extrusion Process on Performance of 6005A Vehicle Body Profile
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Study on Influence of Chemical Compositions and Extrusion Process on Performance of 6005A Vehicle Body Profile
合金成分与挤压工艺对6005A车体型材性能的影响研究
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烧结烟气脱硫是钢铁行业二氧化硫减排的关键
Sintering Flue Gas Desulphurization is the Key of Sulfur Dioxide Emission Reduction of Steel Industry
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Sintering Flue Gas Desulphurization is the Key of Sulfur Dioxide Emission Reduction of Steel Industry
烧结烟气脱硫是钢铁行业二氧化硫减排的关键
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天童山常绿阔叶林土壤呼吸的空间异质性研究:取样数量的估算和取样方法的优化
Spatial Variability of Soil Respiration in Evergreen Board-Leaf Forest: Estimation of the Number of Sampling Points Required and Optimal Sampling Strategy
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Spatial Variability of Soil Respiration in Evergreen Board-Leaf Forest: Estimation of the Number of Sampling Points Required and Optimal Sampling Strategy
天童山常绿阔叶林土壤呼吸的空间异质性研究:取样数量的估算和取样方法的优化
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瑞芬太尼靶控输注在腹腔镜胆囊术中的效果研究
The Effect of Target Controlled Infusion of Remifentanil in the Case of Operation on Gallblader via Abdominal Speculum
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The Effect of Target Controlled Infusion of Remifentanil in the Case of Operation on Gallblader via Abdominal Speculum
瑞芬太尼靶控输注在腹腔镜胆囊术中的效果研究
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长江经济带气象保障问题分析与机制创新研究
Analysis of meteorological support for Yangtze River Economic Belt and study of mechanism innovation
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Analysis of meteorological support for Yangtze River Economic Belt and study of mechanism innovation
长江经济带气象保障问题分析与机制创新研究
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模拟降雨条件下坡地氮素流失特征试验分析
Analysis of the Nitrogen Loss Character on the Slopes under Simulating Rainfall Condition
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Analysis of the Nitrogen Loss Character on the Slopes under Simulating Rainfall Condition
模拟降雨条件下坡地氮素流失特征试验分析
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我国硫铁矿固废综合利用及其环境意义
Comprehensive utilization of pyrite solid wastes in China and its environmental significance
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Comprehensive utilization of pyrite solid wastes in China and its environmental significance
我国硫铁矿固废综合利用及其环境意义
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飞行器舵机电动加载测试系统的研究
Electric Loading Test System For Aircraft Rudder
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Electric Loading Test System For Aircraft Rudder
飞行器舵机电动加载测试系统的研究
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航海模拟器中靠离码头训练的特殊设计。针对航海模拟器在进行靠离码头训练时,舰艇指挥员观察指挥范围受限,环幕视景系统又存在距离感不强的问题,对航海模拟器中靠离码头训练进行特殊设计。介绍缆绳交互界面设计、多视点观察通道设计和视景系统的信息辅助提示设计,并给出仿真效果图。结果表明:该设计能使舰艇指挥员直观地观察到码头周围的情况,看到锚缆的状态和听到舰艇来车的情况,同时通过直接提示得到本舰距码头距离。
Special Designs for Docking Training in Marine Simulator. To solve the problem that the limited range of watching and the poor sense of distance in the visual column screen, this paper uses some appropriate ways of special design during the dock training in the navigation simulator. It introduces the cable interface design, multi-view observation channel design and its visual auxiliary information design, and gives the simulation effect diagram. The results show that these special designs make ship commanders directly observe the situation surrounding the pier, see the mooring state and hear the ships to the engines, and obtain the distance from the ship to the berth by direct cue.
Please translate the following sentences from English to Chinese.
Special Designs for Docking Training in Marine Simulator. To solve the problem that the limited range of watching and the poor sense of distance in the visual column screen, this paper uses some appropriate ways of special design during the dock training in the navigation simulator. It introduces the cable interface design, multi-view observation channel design and its visual auxiliary information design, and gives the simulation effect diagram. The results show that these special designs make ship commanders directly observe the situation surrounding the pier, see the mooring state and hear the ships to the engines, and obtain the distance from the ship to the berth by direct cue.
航海模拟器中靠离码头训练的特殊设计。针对航海模拟器在进行靠离码头训练时,舰艇指挥员观察指挥范围受限,环幕视景系统又存在距离感不强的问题,对航海模拟器中靠离码头训练进行特殊设计。介绍缆绳交互界面设计、多视点观察通道设计和视景系统的信息辅助提示设计,并给出仿真效果图。结果表明:该设计能使舰艇指挥员直观地观察到码头周围的情况,看到锚缆的状态和听到舰艇来车的情况,同时通过直接提示得到本舰距码头距离。
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基于UV位置图的视频三维人脸表情克隆
Video 3D Facial Expression Cloning Based on UV Position Map
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Video 3D Facial Expression Cloning Based on UV Position Map
基于UV位置图的视频三维人脸表情克隆
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QStE650TM高强钢的变截面纵梁冲压可行性研究
Study on stamping feasibility of variable section side member of QStE650TM high strength steel
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Study on stamping feasibility of variable section side member of QStE650TM high strength steel
QStE650TM高强钢的变截面纵梁冲压可行性研究
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SMT焊点半经验随机振动疲劳寿命累积模型
Random Fatigue Semi - experimental Model of SMT Solder Joint in Random Vibration Condition
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Random Fatigue Semi - experimental Model of SMT Solder Joint in Random Vibration Condition
SMT焊点半经验随机振动疲劳寿命累积模型
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石英音叉传感器测量流体密度和黏度的研究
Study on Fluid Density and Viscosity Measured by Quartz Tuning Fork Sensor
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Study on Fluid Density and Viscosity Measured by Quartz Tuning Fork Sensor
石英音叉传感器测量流体密度和黏度的研究
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银川市商品住宅价格与环境的响应分析。由调查问卷结果得出,银川市居民在选择住宅区位时,影响商品住宅价格的主要因子是区位因子,交通条件因子,教育设施因子,自然环境因子.运用缓冲区分析方法分别提取103个商品住宅小区的TM-NDVI指数来定量反映样本周围的环境状况,提取道路长度、公交站点数来定量反映样本的交通便捷度,提取中小学个数来定量的反映样本周围的教育设施状况.在此基础上,结合定量与定性的分析方法进一步研究银川市三个市辖区居住环境与价格的响应关系,金凤区价格与环境的响应度最高,其次是西夏区,兴庆区的响应系数为负相关.
A Study on the Relationship between Environment and Prices of Commercial Residential Bulidings in Yinchuan. Using the questionnaire,it was found that location factors,transportation factors,education facilities factors and natural environmental factors influence the price of commercial residential bulidings when the residents of Yinchuan select the housing location.Using the buffer analysis,the author extracts the TM-NDVI index from 103 commercial residential districts in Yinchuan to quantitatively reflect the state of the environment,extracts the road length,the number of bus stops to quantitatively reflect the transportation convience,and extracts the number of primary and secondary schools to quantitatively reflect the state of the education facilities.Combining quantitative with qualitative analysis,the relationship between environment and prices of commercial residential bulidings in he three municipal districts of Yinchuan was studied further,that the price of the bulidings is most related to environment in Jinfeng district,which comes to the results showed the second in Xixia district and the the correlation in Xingqing district is negative.
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A Study on the Relationship between Environment and Prices of Commercial Residential Bulidings in Yinchuan. Using the questionnaire,it was found that location factors,transportation factors,education facilities factors and natural environmental factors influence the price of commercial residential bulidings when the residents of Yinchuan select the housing location.Using the buffer analysis,the author extracts the TM-NDVI index from 103 commercial residential districts in Yinchuan to quantitatively reflect the state of the environment,extracts the road length,the number of bus stops to quantitatively reflect the transportation convience,and extracts the number of primary and secondary schools to quantitatively reflect the state of the education facilities.Combining quantitative with qualitative analysis,the relationship between environment and prices of commercial residential bulidings in he three municipal districts of Yinchuan was studied further,that the price of the bulidings is most related to environment in Jinfeng district,which comes to the results showed the second in Xixia district and the the correlation in Xingqing district is negative.
银川市商品住宅价格与环境的响应分析。由调查问卷结果得出,银川市居民在选择住宅区位时,影响商品住宅价格的主要因子是区位因子,交通条件因子,教育设施因子,自然环境因子.运用缓冲区分析方法分别提取103个商品住宅小区的TM-NDVI指数来定量反映样本周围的环境状况,提取道路长度、公交站点数来定量反映样本的交通便捷度,提取中小学个数来定量的反映样本周围的教育设施状况.在此基础上,结合定量与定性的分析方法进一步研究银川市三个市辖区居住环境与价格的响应关系,金凤区价格与环境的响应度最高,其次是西夏区,兴庆区的响应系数为负相关.
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跨企业研发合作、研发人力资本对企业创新绩效的影响研究
Research on the Impact of Cross Enterprise R&D Cooperation and R&D Human Capital on Enterprise Innovation Performance
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Research on the Impact of Cross Enterprise R&D Cooperation and R&D Human Capital on Enterprise Innovation Performance
跨企业研发合作、研发人力资本对企业创新绩效的影响研究
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幽情壮采妇女图——王建妇女题作综述
Keen and Significant Picture on Women——Comment Wang Jian Poems on Women
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Keen and Significant Picture on Women——Comment Wang Jian Poems on Women
幽情壮采妇女图——王建妇女题作综述
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血管紧张素Ⅱ在A375细胞株的表达及其对血管新生的影响。目的 探讨血管紧张素Ⅱ( AngⅡ)在恶性黑素瘤(恶黑)细胞的表达情况及AngⅡ对A375血管新生的影响. 方法 放免法检测人恶黑细胞株A375及人正常黑素细胞培养上清液中AngⅡ的表达水平,体外小管形成实验检测AngⅡ对人脐静脉内皮细胞(HUVEC)体外小管形成的影响,逆转录聚合酶链反应(RT-PCR)及酶联免疫吸附试验(ELISA)法检测A375细胞分别在AngⅡ及AngⅡ受体1(AT1R)特异性拮抗剂洛沙坦作用前后血管内皮细胞生长因子(VEGF)及碱性成纤维细胞生长因子(bFGF)的表达.结果 A375细胞株培养上清液中AngⅡ表达水平为(37.29±0.27) pmol/L,较正常人黑素细胞(21.58±0.32 pmol/L)明显增高,差异有统计学意义(P<0.05).AngⅡ能明显诱导HUVEC管状结构的形成,1 μmol/L AngⅡ处理后,二维基质胶中HUVEC形成完整的管状结构,其面积明显高于对照组,为对照组(2.5±0.3)倍,差异有统计学意义(P<0.05).AngⅡ处理后,VEGF及bFGF在A375细胞mRNA及蛋白水平的表达较处理前明显增高,1 μmol/L洛沙坦作用后则正好相反,差异有统计学意义(P<0.05).结论 A375细胞株存在着AngⅡ的超表达,AngⅡ能明显促进其血管新生,可能是局部肾素-血管紧张素系统影响恶黑肿瘤发生的机制之一.
Expression of angiotensin Ⅱ in A375 human malignant melanoma cells and its influence on angiogenesis. Objective To investigate the expression of angiotensin Ⅱ (Ang Ⅱ) in malignant melanoma cells and to explore the influence of Ang Ⅱ on angiogenesis. Methods The expression of Ang Ⅱ in the supernatant of A375 cells and primary human melanocytes was detected by radioimmunoassay.Human umbilical vein endothelial cells (HUVECs) were incubated with Ang Ⅱ of 1 μmol/L for 20 hours in an in vitro tube formation assay to observe the effects of Ang Ⅱ on tube formation.A375 cells were incubated with angiotensin Ⅱ of 1 μmol/L and losartan (an inhibitor of angiotensin Ⅱ type 1 receptor,AT1R) of 1 μmol/L,respectively for 24 hours; subsequently, reverse transcription PCR (RT-PCR) and enzyme-linked immunosorbent assay (ELISA)were carried out to measure the mRNA and protein expressions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF),respectively.Results The level of Ang Ⅱ was 37.29 ± 0.27 pmol/L in the supernatant of A375 cells,significantly higher than that in the supernatant of normal human melanocytes (21.58 ± 0.32 pmol/L,P < 0.05).Ang Ⅱ apparently promoted the tube formation by HUVECs.Intact tubiform structures were formed by HUVECs in two-dimension matrigel after being treated with Ang Ⅱ of 1 μmol/L,with the area of tubiform structures being 2.5 ± 0.3 times that in the HUVECs treated with phosphate buffered solution (PBS) (P < 0.05).The protein expressions of VEGF and bFGF in the supernatant of A375 cells and their mRNA expressions in A375 cells were significantly increased by Ang Ⅱ,but suppressed by losartan (all P < 0.05).Conclusions There is a local overexpression of Ang Ⅱ in malignant melanoma,which can markedly promote angiogenesis.This may be one of the mechanisms by which the local renin-angiotensin system affects the initiation of malignant melanoma.
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Expression of angiotensin Ⅱ in A375 human malignant melanoma cells and its influence on angiogenesis. Objective To investigate the expression of angiotensin Ⅱ (Ang Ⅱ) in malignant melanoma cells and to explore the influence of Ang Ⅱ on angiogenesis. Methods The expression of Ang Ⅱ in the supernatant of A375 cells and primary human melanocytes was detected by radioimmunoassay.Human umbilical vein endothelial cells (HUVECs) were incubated with Ang Ⅱ of 1 μmol/L for 20 hours in an in vitro tube formation assay to observe the effects of Ang Ⅱ on tube formation.A375 cells were incubated with angiotensin Ⅱ of 1 μmol/L and losartan (an inhibitor of angiotensin Ⅱ type 1 receptor,AT1R) of 1 μmol/L,respectively for 24 hours; subsequently, reverse transcription PCR (RT-PCR) and enzyme-linked immunosorbent assay (ELISA)were carried out to measure the mRNA and protein expressions of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF),respectively.Results The level of Ang Ⅱ was 37.29 ± 0.27 pmol/L in the supernatant of A375 cells,significantly higher than that in the supernatant of normal human melanocytes (21.58 ± 0.32 pmol/L,P < 0.05).Ang Ⅱ apparently promoted the tube formation by HUVECs.Intact tubiform structures were formed by HUVECs in two-dimension matrigel after being treated with Ang Ⅱ of 1 μmol/L,with the area of tubiform structures being 2.5 ± 0.3 times that in the HUVECs treated with phosphate buffered solution (PBS) (P < 0.05).The protein expressions of VEGF and bFGF in the supernatant of A375 cells and their mRNA expressions in A375 cells were significantly increased by Ang Ⅱ,but suppressed by losartan (all P < 0.05).Conclusions There is a local overexpression of Ang Ⅱ in malignant melanoma,which can markedly promote angiogenesis.This may be one of the mechanisms by which the local renin-angiotensin system affects the initiation of malignant melanoma.
血管紧张素Ⅱ在A375细胞株的表达及其对血管新生的影响。目的 探讨血管紧张素Ⅱ( AngⅡ)在恶性黑素瘤(恶黑)细胞的表达情况及AngⅡ对A375血管新生的影响. 方法 放免法检测人恶黑细胞株A375及人正常黑素细胞培养上清液中AngⅡ的表达水平,体外小管形成实验检测AngⅡ对人脐静脉内皮细胞(HUVEC)体外小管形成的影响,逆转录聚合酶链反应(RT-PCR)及酶联免疫吸附试验(ELISA)法检测A375细胞分别在AngⅡ及AngⅡ受体1(AT1R)特异性拮抗剂洛沙坦作用前后血管内皮细胞生长因子(VEGF)及碱性成纤维细胞生长因子(bFGF)的表达.结果 A375细胞株培养上清液中AngⅡ表达水平为(37.29±0.27) pmol/L,较正常人黑素细胞(21.58±0.32 pmol/L)明显增高,差异有统计学意义(P<0.05).AngⅡ能明显诱导HUVEC管状结构的形成,1 μmol/L AngⅡ处理后,二维基质胶中HUVEC形成完整的管状结构,其面积明显高于对照组,为对照组(2.5±0.3)倍,差异有统计学意义(P<0.05).AngⅡ处理后,VEGF及bFGF在A375细胞mRNA及蛋白水平的表达较处理前明显增高,1 μmol/L洛沙坦作用后则正好相反,差异有统计学意义(P<0.05).结论 A375细胞株存在着AngⅡ的超表达,AngⅡ能明显促进其血管新生,可能是局部肾素-血管紧张素系统影响恶黑肿瘤发生的机制之一.
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非破坏性水分测量仪的设计
Design for Non-destructive Moisture Content Detector
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Design for Non-destructive Moisture Content Detector
非破坏性水分测量仪的设计
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纹状体区神经肽表达的改变与左旋多巴诱发异动症的关系
Relationship between Changes of Specific Neuropeptide Gene in Striatum and Pathogenesis of Levodopa-induced Dyskinesias
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Relationship between Changes of Specific Neuropeptide Gene in Striatum and Pathogenesis of Levodopa-induced Dyskinesias
纹状体区神经肽表达的改变与左旋多巴诱发异动症的关系
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黄河三角洲海水灌溉对土壤性质的影响研究
Study on Effect of Seawater Irrigation to Soil Properties in Yellow River Delta
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Study on Effect of Seawater Irrigation to Soil Properties in Yellow River Delta
黄河三角洲海水灌溉对土壤性质的影响研究
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家用冰箱微生物污染现状调查
Investigation on status of microbial contamination of domestic refrigerators
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Investigation on status of microbial contamination of domestic refrigerators
家用冰箱微生物污染现状调查
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复杂介质中地震波模拟的无单元法
A Mesh-Free Algorithm of Seismic Wave Simulation in Complex Medium
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A Mesh-Free Algorithm of Seismic Wave Simulation in Complex Medium
复杂介质中地震波模拟的无单元法
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应用尺桡骨交锁髓内钉治疗前臂粉碎性骨折
Interlocking Intramedullary Nailing for Treatment of Comminuted Fractures of Forearm
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Interlocking Intramedullary Nailing for Treatment of Comminuted Fractures of Forearm
应用尺桡骨交锁髓内钉治疗前臂粉碎性骨折
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基于Sol-gel膜和多壁碳纳米管/铂纳米颗粒增效的电流型L-乳酸生物传感器
Amperometric L-lactate Biosensor Based on Sol-Gel Film and Multi-walled Carbon Nanotubes/Platinum Nanoparticles Enhancement
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Amperometric L-lactate Biosensor Based on Sol-Gel Film and Multi-walled Carbon Nanotubes/Platinum Nanoparticles Enhancement
基于Sol-gel膜和多壁碳纳米管/铂纳米颗粒增效的电流型L-乳酸生物传感器
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术后早期经口肠内营养对结直肠癌患者康复和免疫功能的影响。目的 观察早期进食肠内营养制剂对结直肠癌患者临床结局和免疫功能的影响.方法 88例结直肠癌患者随机分为试验组(43例)和对照组(45例).试验组术后早期少量多次进水和肠内营养制剂,对照组采用传统治疗方案.比较2组患者术前和术后第1、3、7天IgA、IgG、IgM以及CD4+、CD4+/CD8+和C-反应蛋白(C-reactive protien,CRP)水平,记录术后住院天数、并发症及生活质量等指标.结果 试验组术后发热时间[(54±6)h比(65 ±6)h,=8.688,P<0.01]、排气时间[(58±8)h比(72 ±7)h,t=8.573,P<0.01]、住院时间[(6.9±1.4)d比(8.5±1.9)d,t=4.277,P<0.01]以及治疗费用[(41 868 ±3 168)元比(45 950±3 714)元,t=5.536,P<0.01]明显少于对照组,差异有统计学意义,而2组术后并发症发生[18.6% (8/43)比22.2% (10/45),t=0.177,P>0.05]相比差异无统计学意义;试验组出院时生活质量评分[(18.4±1.7)比(16.4±1.9),t=5.235,P<0.01]明显高于对照组.术后第7天试验组CD4+、CD4 +/CD8+和IgM水平明显高于对照组(t=3.639,t =2.255,t=2.119,P<0.05);术后第3天和第7天试验组IgA、IgG明显高于对照组(t=2.035,t =2.961,t=2.060,t =2.108,P<0.05);术后第3天和第7天试验组CRP水平明显低于对照组(t =7.308,t=3.435,P<0.05).结论 术后早期进食肠内营养制剂能够改善结直肠癌患者免疫功能,降低应激反应、促进康复.
Effects of early enteral feeding on clinical outcomes and immune function in patients after colorectal cancer surgery. Objective To observe the effect of early enteral feeding on clinical outcomes and immune function in patients after colorectal cancer surgery.Methods 90 cases of colorectal cancer patients were randomly divided into early enteral feeding group (43 cases) and control group (45 cases).Patients in early feeding group were given small amount of water several times and enteral nutrition early after surgery,while patients in the control group were administrated according to conventional postoperative care protocol.Data were collected on serum IgA,IgG,IgM,CD4 +,CD4 +/CD8 + and CRP on the postoperative first,third and seventh days,postoperative length of stay,complications and quality of life.Results The postoperative fever time [(54 ±6) h vs.(65 ±6) h,t =8.688,P <0.01],time to flatus [(58 ±8) h vs.(72±7) h,t=8.573,P<0.01],postoperative length of stay [(6.9±1.4) dvs.(8.5 ±1.9) d,t=4.277,P < 0.01] and health care cost [(41 868 ± 3 168) RMB vs.(45 950 ± 3 714) RMB,t =5.536,P < 0.01] were significantly in favour of early enteral feeding group than those in control group.Further,the score of quality of life at discharge were significantly higher in early enteral feeding group [(18.4 ± 1.7) vs.(16.4 ± 1.9),t =5.235,P < 0.01],while the complication incidence showed no difference between the two groups [18.6% (8/43) vs.22.2% (10/45),t=0.177,P>0.05].The CD4+,CD4+/CD8+ and IgM on the seventh postoperative day and the IgA and IgG on the third and seventh postoperative day were significantly better in early enteral feeding group while the CRP was significantly lower as compared to the control group (t =3.639,t =2.255,t =2.119,t =2.035,t =2.961,t =2.060,t =2.108,t =7.308,t =3.435,P < 0.05).Conclusions Early oral enteral feeding after elective colorectal cancer surgery can improve patient's immune function,reduce the stress and accelerate rehabilitation.
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Effects of early enteral feeding on clinical outcomes and immune function in patients after colorectal cancer surgery. Objective To observe the effect of early enteral feeding on clinical outcomes and immune function in patients after colorectal cancer surgery.Methods 90 cases of colorectal cancer patients were randomly divided into early enteral feeding group (43 cases) and control group (45 cases).Patients in early feeding group were given small amount of water several times and enteral nutrition early after surgery,while patients in the control group were administrated according to conventional postoperative care protocol.Data were collected on serum IgA,IgG,IgM,CD4 +,CD4 +/CD8 + and CRP on the postoperative first,third and seventh days,postoperative length of stay,complications and quality of life.Results The postoperative fever time [(54 ±6) h vs.(65 ±6) h,t =8.688,P <0.01],time to flatus [(58 ±8) h vs.(72±7) h,t=8.573,P<0.01],postoperative length of stay [(6.9±1.4) dvs.(8.5 ±1.9) d,t=4.277,P < 0.01] and health care cost [(41 868 ± 3 168) RMB vs.(45 950 ± 3 714) RMB,t =5.536,P < 0.01] were significantly in favour of early enteral feeding group than those in control group.Further,the score of quality of life at discharge were significantly higher in early enteral feeding group [(18.4 ± 1.7) vs.(16.4 ± 1.9),t =5.235,P < 0.01],while the complication incidence showed no difference between the two groups [18.6% (8/43) vs.22.2% (10/45),t=0.177,P>0.05].The CD4+,CD4+/CD8+ and IgM on the seventh postoperative day and the IgA and IgG on the third and seventh postoperative day were significantly better in early enteral feeding group while the CRP was significantly lower as compared to the control group (t =3.639,t =2.255,t =2.119,t =2.035,t =2.961,t =2.060,t =2.108,t =7.308,t =3.435,P < 0.05).Conclusions Early oral enteral feeding after elective colorectal cancer surgery can improve patient's immune function,reduce the stress and accelerate rehabilitation.
术后早期经口肠内营养对结直肠癌患者康复和免疫功能的影响。目的 观察早期进食肠内营养制剂对结直肠癌患者临床结局和免疫功能的影响.方法 88例结直肠癌患者随机分为试验组(43例)和对照组(45例).试验组术后早期少量多次进水和肠内营养制剂,对照组采用传统治疗方案.比较2组患者术前和术后第1、3、7天IgA、IgG、IgM以及CD4+、CD4+/CD8+和C-反应蛋白(C-reactive protien,CRP)水平,记录术后住院天数、并发症及生活质量等指标.结果 试验组术后发热时间[(54±6)h比(65 ±6)h,=8.688,P<0.01]、排气时间[(58±8)h比(72 ±7)h,t=8.573,P<0.01]、住院时间[(6.9±1.4)d比(8.5±1.9)d,t=4.277,P<0.01]以及治疗费用[(41 868 ±3 168)元比(45 950±3 714)元,t=5.536,P<0.01]明显少于对照组,差异有统计学意义,而2组术后并发症发生[18.6% (8/43)比22.2% (10/45),t=0.177,P>0.05]相比差异无统计学意义;试验组出院时生活质量评分[(18.4±1.7)比(16.4±1.9),t=5.235,P<0.01]明显高于对照组.术后第7天试验组CD4+、CD4 +/CD8+和IgM水平明显高于对照组(t=3.639,t =2.255,t=2.119,P<0.05);术后第3天和第7天试验组IgA、IgG明显高于对照组(t=2.035,t =2.961,t=2.060,t =2.108,P<0.05);术后第3天和第7天试验组CRP水平明显低于对照组(t =7.308,t=3.435,P<0.05).结论 术后早期进食肠内营养制剂能够改善结直肠癌患者免疫功能,降低应激反应、促进康复.
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米仓山前陆盆地东段构造演化模式与油气聚集
Tectonic evolution and oil and gas accumulation in the east Micangshan foreland Basin, Sichuan
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Tectonic evolution and oil and gas accumulation in the east Micangshan foreland Basin, Sichuan
米仓山前陆盆地东段构造演化模式与油气聚集
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双无衍射光束三角测量系统。提出可用于物体轮廓在线抗振测量的双无衍射光束三角测量系统.系统以双无衍射光束作为测量光束,结构简单灵活.给出了系统结构及原理,推导了相关算法,并在振动条件下进行了实验.结果说明,该系统能有效地去除振动噪声的影响.
Triangulation System Based on Dual Non-diffracting Beams. Dual non-diffracting beams based on triangulation system are proposed. This system can be used for in-process vibration resistant in profile measurement. In this system, the dual non-diffracting beams are used as incident beams. The system structure is simple and flexible. The system structure and principle are introduced. The corresponding calculation algorithms are deduced. The experimental tests under vibration condition are carried out and the results illustrate that the influence of vibration noise has been removed effectively.
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Triangulation System Based on Dual Non-diffracting Beams. Dual non-diffracting beams based on triangulation system are proposed. This system can be used for in-process vibration resistant in profile measurement. In this system, the dual non-diffracting beams are used as incident beams. The system structure is simple and flexible. The system structure and principle are introduced. The corresponding calculation algorithms are deduced. The experimental tests under vibration condition are carried out and the results illustrate that the influence of vibration noise has been removed effectively.
双无衍射光束三角测量系统。提出可用于物体轮廓在线抗振测量的双无衍射光束三角测量系统.系统以双无衍射光束作为测量光束,结构简单灵活.给出了系统结构及原理,推导了相关算法,并在振动条件下进行了实验.结果说明,该系统能有效地去除振动噪声的影响.
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重庆市大型科学仪器资源共享平台建设
Probe and Practice of Chongqing Large Scientific Instruments Resource Sharing Platform's Construction
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Probe and Practice of Chongqing Large Scientific Instruments Resource Sharing Platform's Construction
重庆市大型科学仪器资源共享平台建设
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不同基底瓷厚度对IPS e.max press全瓷冠应力影响的有限元分析
Influence of core thickness on the stress of IPS e.max press crown using finite element analysis
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Influence of core thickness on the stress of IPS e.max press crown using finite element analysis
不同基底瓷厚度对IPS e.max press全瓷冠应力影响的有限元分析
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论马克思哲学语境中的群众概念
On Concept of Mass in the Context of Marx's Philosophy
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On Concept of Mass in the Context of Marx's Philosophy
论马克思哲学语境中的群众概念
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郑州市2012-2015年手足口病流行特征分析
Analysis on epidemic characteristic of HFMD in Zhengzhou City from 2012 to 2015
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Analysis on epidemic characteristic of HFMD in Zhengzhou City from 2012 to 2015
郑州市2012-2015年手足口病流行特征分析
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深圳市药品集中采购对降低药品费用的成效研究
Study on the effectiveness of GPO in reducing drug costs in Shenzhen
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Study on the effectiveness of GPO in reducing drug costs in Shenzhen
深圳市药品集中采购对降低药品费用的成效研究
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热加工食品中呋喃的研究进展
Recent Progress of Furan in Heat-Processed Foods
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Recent Progress of Furan in Heat-Processed Foods
热加工食品中呋喃的研究进展