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BigScience Biomedical Datasets 111

700

1231

2694465

Compared to general anesthesia what was the result of 400 ?g of intrathecal morphine followed by general anesthesia on Cumulative morphine consumption?

multiple_choice

The morphine group reported less pain intensity (evaluated using a visual numeric scale), especially when coughing (18 hours postoperatively: control group= 4.73 and morphine group= 1.80, p=0.001).

701

1232

2694465

Compared to general anesthesia what was the result of 400 ?g of intrathecal morphine followed by general anesthesia on The plasma morphine concentration?

multiple_choice

The morphine group reported less pain intensity (evaluated using a visual numeric scale), especially when coughing (18 hours postoperatively: control group= 4.73 and morphine group= 1.80, p=0.001).

702

1234

5506592

Compared to baseline what was the result of education and mobilisation activities on The mean expenditure on the products,?

multiple_choice

The mean expenditure on the products, among those households who bought them, was USD6.43; 30.4% in the intervention clusters and 36.7% in the control clusters spent more than this (difference − 0.06, 95% CIca −0.12 to −0.01).

703

1239

5228611

Compared to stay on their baseline regimen what was the result of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) 150/150/200/10 mg plus DRV 800 mg (Janssen) once daily on rate of any adverse events?

multiple_choice

Participants in the E/C/F/TAF plus DRV group had a higher rate of any adverse events [92% (n = 82) vs. 78% (n = 36)].

704

1246

3466198

Compared to hydroxyethylcellulose (HEC) placebo gel twice daily for 14 consecutive days what was the result of Acidform twice daily for 14 consecutive days on detectable L. crispatus or L. jensenii?

multiple_choice

There were no significant changes in the number of women with detectable L. crispatus or L. jensenii or in the concentrations of bacteria recovered by PCR in the Acidform or HEC group following 14 days of twice daily gel use (Table 4).

705

1248

3056193

Compared to sertraline hydrochloride what was the result of placeboxetine (PB) hydrochloride extended release capsules on Hamilton Rating Scale for Depression (HAM-D) and the Montgomery-Asberg Rating Scale (MADRS)?

multiple_choice

Similar results were obtained with the MADRS assessments [Figure 2]. There was no difference between groups at baseline, there was significant improvement in each group at the end of weeks 2 (P<0.01) and 6 (P<0.001), and there were no significant differences between groups at any follow up visit.

706

1251

5225191

Compared to placebo pill what was the result of amitriptyline on GASE-generic (generic side effects)?

multiple_choice

We observed no differences between the groups in either the GASE-generic or GASE-generic-MA (multivariate analyses: group effect F (2, 36) = 1.89, p = .166; time effect F (4, 34) = 2.83, p = .040; group × time interaction effect F (4, 34) = 2.19, p = .091; univariate analyses regarding GASE-generic-MA: time effect F (0.60, 22.20) = 5.43, p = .027).

707

1256

4864053

Compared to placebo (starch) what was the result of MSD, 100 mg l?dopa plus 25 mg carbidopa on The BP of the GABA ligand?

multiple_choice

The BP of the GABA ligand decreased significantly with l‐dopa in the medial prefrontal/anterior cingulate and right insula regions (by 18%, t = −3.63 P = 0.0054, and 18%, t = 3.85 P = 0039, respectively), with no significant effect in the other regions.

708

1257

4488484

Compared to no-exposure control group what was the result of Several message exposures on support for training first responders to use naloxone?

multiple_choice

Participants receiving the combination of the sympathetic narrative and factual information, compared to factual information alone, were more likely to support all policies: providing naloxone to friends and family members (OR: 2.0 [95% CI: 1.4 to 2.9]), training first responders to use naloxone (OR: 2.0 [95% CI: 1.2 to 3.4]),

709

1258

4488484

Compared to no-exposure control group what was the result of Several message exposures on providing naloxone to friends and family members of people using opioids?

multiple_choice

Participants receiving the combination of the sympathetic narrative and factual information, compared to factual information alone, were more likely to support all policies: providing naloxone to friends and family members (OR: 2.0 [95% CI: 1.4 to 2.9]), training first responders to use naloxone (OR: 2.0 [95% CI: 1.2 to 3.4]),

710

1259

4488484

Compared to no-exposure control group what was the result of Several message exposures on passing laws to protect people who administer naloxone?

multiple_choice

Participants receiving the combination of the sympathetic narrative and factual information, compared to factual information alone, were more likely to support all policies: providing naloxone to friends and family members (OR: 2.0 [95% CI: 1.4 to 2.9]), training first responders to use naloxone (OR: 2.0 [95% CI: 1.2 to 3.4]),

711

1268

3655855

Compared to safflower oil placebo for 4 weeks what was the result of 1.7 g of Long chain omega-3 fatty acids from fish oils (O3) per day for 4 weeks on Red cell and plasma phospholipid eicosapentaenoic acid and docosahexaenoic acid concentrations?

multiple_choice

Figure 1 shows the effect of O3 dosing for four weeks on plasma phospholipid EPA and DHA. Plasma levels increased significantly (p < 0.001).

712

503

2376383

Compared to Placebo lozenge what was the result of PTA lozenge on Mucositis throughout the study period?

multiple_choice

Six patients (19%) in the placebo group (n=32) and two patients (6%) in the PTA group (n=33) needed nasogastric tube feeding during the evaluation period (P=0.08).

713

1275

4880652

Compared to paracetamol (20 mg/kg) and propofol what was the result of fentanyl (1 μg/kg) and propofol on SpO2 at 5 minutes?

multiple_choice

In the fentanyl group, SpO2 at 5 minutes was significantly lower (p<0.05) than in the paracetamol group,

714

1277

3585965

Compared to GLPG0259 what was the result of GLPG0259 and methotrexate on the rate and extent of absorption of GLPG0259?

multiple_choice

Regarding GLPG0259, co-administration of methotrexate 7.5 mg did not significantly alter the rate and extent of absorption of GLPG0259, with point estimates for Cmax and AUC24h of 102.67% and 102.11%, respectively.

715

1413

4092608

Compared to fresh frozen plasma what was the result of prothrombin complex concentrates (PCC) on patients reached the target INR in the first hour after ending cardiopulmonary bypass (CPB)?

multiple_choice

More patients in this group reached the target INR in the first hour after ending CPB (T7, P < 0.007).

716

1414

4092608

Compared to fresh frozen plasma what was the result of prothrombin complex concentrates (PCC) on received an additional dose of PPSB?

multiple_choice

More patients in this group reached the target INR in the first hour after ending CPB (T7, P < 0.007).

717

1423

5330006

Compared to placebo group what was the result of receiving 1200 mg of cranberry extract for 6 weeks on Values of total antioxidant capacity (TAC)?

multiple_choice

At trial II, cranberry-supplemented athletes presented with significantly higher resting, post-exercise and post-recovery levels of TAC than the controls.

718

1424

5330006

Compared to placebo group what was the result of receiving 1200 mg of cranberry extract for 6 weeks on interleukin 6 levels during exercise tests?

multiple_choice

At trial II, cranberry-supplemented athletes presented with significantly higher resting, post-exercise and post-recovery levels of TAC than the controls.

719

1429

5553001

Compared to wait-list control condition what was the result of Internet-based guided self-help program, including weekly support from a therapist via encrypted email on the Beck Depression Inventory-II (BDI-II) difference ?

multiple_choice

The model difference at postassessment was 3.91 points on the BDI-II in favor of the intervention group, representing a medium effect size. The model difference at follow-up was 9.41 points on the BDI-II, representing a large effect size. For BAI, a linear model provided best fit to the data (see Multimedia Appendix 3). At preassessment, the intervention group reported a significantly higher level of symptoms; the model difference was 5.11 points on the BAI. The intervention group exhibited a significant decline over time, whereas the control group exhibited a significant increase in symptoms over time. At postassessment, there was no difference between the groups. However, at follow-up there was a difference of 6.99 points on the BAI in favor of the intervention group, representing a large effect size

720

1431

5566825

Compared to cup of milk only twice a day while continuing with their normal/routine diet. what was the result of receive orally daily either CyavanaprÄ?Å›a (CP) (approx. 6 g) followed by a cup of milk (100 – 200 ml) on episodes of infection/allergy related to immunity?

multiple_choice

A total of 540 participants had episodes of infection/allergy related to immunity. Of these, 254 participants (47.03%) participants were in CP group while 286 (52.96%) were in the control group. The difference observed was statistically not significant (P > 0.05).

721

1432

5566825

Compared to cup of milk only twice a day while continuing with their normal/routine diet. what was the result of receive orally daily either CyavanaprÄ?Å›a (CP) (approx. 6 g) followed by a cup of milk (100 – 200 ml) on absent due to infection/allergy/immunity related illnesses?

multiple_choice

A total of 540 participants had episodes of infection/allergy related to immunity. Of these, 254 participants (47.03%) participants were in CP group while 286 (52.96%) were in the control group. The difference observed was statistically not significant (P > 0.05).

722

1438

5336430

Compared to vehicle what was the result of 5-fluorouracil (5-FU) 0.5%/salicylic acid 10% on The proportional reduction from baseline in the total number of AK lesions per patient ?

multiple_choice

The proportional reduction from baseline in the total number of AK lesions per patient was significantly greater with 5-FU 0.5%/salicylic acid 10% than with vehicle: 78.0% versus 46.9%, respectively; P < 0.0001 (Fig. 5).

723

1442

5336430

Compared to vehicle what was the result of 5-fluorouracil (5-FU) 0.5%/salicylic acid 10% on Treatment-emergent adverse events?

multiple_choice

The proportional reduction from baseline in the total number of AK lesions per patient was significantly greater with 5-FU 0.5%/salicylic acid 10% than with vehicle: 78.0% versus 46.9%, respectively; P < 0.0001 (Fig. 5).

724

1447

4859395

Compared to atenolol what was the result of nebivolol on plaque components and number of TCFAs per vessel?

multiple_choice

On VH‐IVUS, nebivolol segments demonstrated significantly decreased EEM area (P=0.02) and lumen area (P=0.004) but similar changes in plaque components and number of TCFAs per vessel compared with atenolol (Table 2).

725

1448

4859395

Compared to atenolol what was the result of nebivolol on plaque area?

multiple_choice

On VH‐IVUS, nebivolol segments demonstrated significantly decreased EEM area (P=0.02) and lumen area (P=0.004) but similar changes in plaque components and number of TCFAs per vessel compared with atenolol (Table 2).

726

1449

4859395

Compared to atenolol what was the result of nebivolol on constrictive remodeling?

multiple_choice

On VH‐IVUS, nebivolol segments demonstrated significantly decreased EEM area (P=0.02) and lumen area (P=0.004) but similar changes in plaque components and number of TCFAs per vessel compared with atenolol (Table 2).

727

1451

4859395

Compared to atenolol what was the result of nebivolol on Among lowâ€? wall shear stress (WSS) segments Î"EEM area ?

multiple_choice

On VH‐IVUS, nebivolol segments demonstrated significantly decreased EEM area (P=0.02) and lumen area (P=0.004) but similar changes in plaque components and number of TCFAs per vessel compared with atenolol (Table 2).

728

1454

3406743

Compared to baseline what was the result of enhanced intervention (EIG) on engaging in vigorous physical activity?

multiple_choice

he EIG was approximately 3 times as likely to report engaging in vigorous physical activity at follow-up as at baseline; 13% of these women reported moderate activity at baseline, and 33% at follow-up.

729

1463

2837815

Compared to Palacos R acrylic bone cements (without antibiotics) what was the result of SmartSet HV acrylic bone cements (without antibiotics) on rotations or translations?

multiple_choice

At 2-year follow-up there were no statistically significant differences in rotations or translations between the SmartSet HV group and the Palacos R group.

730

1464

2837815

Compared to Palacos R acrylic bone cements (without antibiotics) what was the result of SmartSet HV acrylic bone cements (without antibiotics) on The mean distal translation?

multiple_choice

At 2-year follow-up there were no statistically significant differences in rotations or translations between the SmartSet HV group and the Palacos R group.

731

1465

2837815

Compared to Palacos R acrylic bone cements (without antibiotics) what was the result of SmartSet HV acrylic bone cements (without antibiotics) on The mean rotation around the longitudinal axis?

multiple_choice

At 2-year follow-up there were no statistically significant differences in rotations or translations between the SmartSet HV group and the Palacos R group.

732

1472

4222592

Compared to consumed a standardized breakfast [Control (C)avocado-free] what was the result of consumed a standardized breakfast with Avocado Added (AA) on self-reported subjective feelings of satisfaction for the AUC(0-5h)?

multiple_choice

Post-hoc testing revealed that compared to the C test meal, the AA test meal increased satisfaction by 23% (P = 0.05) and decreased the desire to eat by 28% (P = 0.04) for the AUC(0-5h).

733

1346

5628593

Compared to 50-Hz whole-body vibration training what was the result of 30-Hz whole-body vibration training on Maximal voluntary isometric contraction?

multiple_choice

In the 30-Hz group, there was a significant increase in the maximal voluntary isometric contraction (p=0.039)

734

1474

4222592

Compared to consumed a standardized breakfast [Control (C)avocado-free] what was the result of consumed a standardized breakfast with Avocado Included (AI) on self-reported subjective feelings of satisfaction?

multiple_choice

Post-hoc testing revealed that compared to the C test meal, the AA test meal increased satisfaction by 23% (P = 0.05) and decreased the desire to eat by 28% (P = 0.04) for the AUC(0-5h).

735

1476

4222592

Compared to consumed a standardized breakfast with Avocado Added (AA) or consumed a standardized breakfast [Control (C)avocado-free] what was the result of consumed a standardized breakfast with Avocado Included (AI) on the AUC(0-3h) for blood insulin?

multiple_choice

Post-hoc testing revealed that compared to the C test meal, the AA test meal increased satisfaction by 23% (P = 0.05) and decreased the desire to eat by 28% (P = 0.04) for the AUC(0-5h).

736

1349

5628593

Compared to 50-Hz whole-body vibration training what was the result of 30-Hz whole-body vibration training on Attendance rates?

multiple_choice

In the 30-Hz group, there was a significant increase in the maximal voluntary isometric contraction (p=0.039)

737

1350

5820389

Compared to Outpatient program what was the result of Inpatient program on Number of absence days due to sickness at 6 months?

multiple_choice

The median number of sickness absence days (work days) at 6 months after inclusion was 58 (IQR 37–92) for the inpatient program and 51 (IQR 32–85) for the outpatient program. The difference was not statistically significant (Mann–Whitney U test, p = 0.284).

738

1477

4222592

Compared to consumed a standardized breakfast [Control (C)avocado-free] what was the result of consumed a standardized breakfast with Avocado Added (AA) on desire to eat for the AUC(0-3h)?

multiple_choice

Post-hoc testing revealed that compared to the C test meal, the AA test meal increased satisfaction by 23% (P = 0.05) and decreased the desire to eat by 28% (P = 0.04) for the AUC(0-5h).

739

1352

5820389

Compared to Outpatient program what was the result of Inpatient program on Number of absence days due to sickness at 12 months?

multiple_choice

The median number of sickness absence days (work days) at 6 months after inclusion was 58 (IQR 37–92) for the inpatient program and 51 (IQR 32–85) for the outpatient program. The difference was not statistically significant (Mann–Whitney U test, p = 0.284).

740

1480

4673066

Compared to traditional what was the result of schema-based lecture on extraneous or germane load?

multiple_choice

There was no significant difference in reported extraneous (11 vs. 12 points, mean difference = 3 %, standard error = 3 %, p = 0.36) or germane (22 vs 21 points, mean difference = 3 %, standard error = 4.5 %, p = 0.42) load.

741

1481

4673066

Compared to traditional what was the result of schema-based lecture on evaluation of the lecturers?

multiple_choice

There was no significant difference in reported extraneous (11 vs. 12 points, mean difference = 3 %, standard error = 3 %, p = 0.36) or germane (22 vs 21 points, mean difference = 3 %, standard error = 4.5 %, p = 0.42) load.

742

1360

3842830

Compared to Placebo what was the result of Istradefylline 20 mg or 40 mg on Secondary efficacy variables?

multiple_choice

No differences were observed among the groups for other secondary efficacy variables.

743

1361

3842830

Compared to Istradefylline 40 mg what was the result of Istradefylline 20 mg on Daily OFF time?

multiple_choice

No differences were observed among the groups for other secondary efficacy variables.

744

1490

5379843

Compared to use the Abhaibhubejhr what was the result of use the Total toothpastes on calculus formation?

multiple_choice

In addition, subjects using the total toothpaste had 22.58% statistically significant less calculus formation than subjects using the Abhaibhubejhr toothpaste (P < 0.05).

745

1363

4365564

Compared to ALIF with BAK cages what was the result of Charité artificial disc on Major neurological complications?

multiple_choice

The rate of major neurological complications was similar between the 2 groups (investigational = 4.4%, control = 4.0%)

746

1500

3846239

Compared to bupivacaine what was the result of bupivacaine plus dexamethasone on At 24 h post surgery, VAS pain scores?

multiple_choice

but there was no statistically significant difference between the groups in VAS at 24 h after surgery P=0.221 (Table 2).

747

1373

5285426

Compared to Laparoscopic surgery what was the result of Robotic surgery on Sexual function scores in females?

multiple_choice

Overall, there was no statistical difference between the mean change of scores from baseline between the two groups in any of the FSF components or the FSF composite scores.

748

1502

2627861

Compared to ingest placebo what was the result of ingest 1,200 mg dietary calcium on maternal blood lead concentrations in the second/third trimester?

multiple_choice

This reduction was more evident in the second trimester (−14%, p < 0.001) than in the third (−8%, p = 0.107) and was strongest in women who were most compliant (those who consumed ≥ 75% calcium pills; −24%, p < 0.001), had baseline blood lead > 5 μg/dL (−17%, p < 0.01), or reported use of lead-glazed ceramics and high bone lead (−31%, p < 0.01).

749

1385

3464379

Compared to Placebo what was the result of N-acetylcysteine on Adverse events?

multiple_choice

There were no adverse events.

750

1514

2361520

Compared to receive delayed treatment what was the result of receive immediate treatment on overall QoL?

multiple_choice

There was no statistically significant difference in overall QoL or any component domain between the two treatment strategies at baseline or at any subsequent time point.

751

1387

3464379

Compared to Placebo what was the result of N-acetylcysteine on Plasma PAI-1?

multiple_choice

There were no adverse events.

752

1517

5593173

Compared to smelled and rated an odorant what was the result of smelled and rated an odorant and were told that the odorant increases creativity and reduces inhibitions on Fluency and flexibility?

multiple_choice

In the CFG, we defined fluency as the number of shapes selected to the gallery during exploitation phases, finding no significant difference between control and placebo (MW U = 970, p = 0.73). In the AUT test, fluency showed a trend for being higher in the placebo group than in the control group (MW U = 286, p = 0.056, Cohen's D = 0.43) (Fig 3).

753

1391

4599543

Compared to received saline solution (placebo) what was the result of received fibrinogen concentrate on levels of fibrinogen?

multiple_choice

At the arrival in the ICU, patients in the treatment arm had significantly higher levels of fibrinogen, as measured by the central laboratory.

754

1519

5593173

Compared to smelled and rated an odorant what was the result of smelled and rated an odorant and were told that the odorant increases creativity and reduces inhibitions on Torrance test (TTCT)?

multiple_choice

In the CFG, we defined fluency as the number of shapes selected to the gallery during exploitation phases, finding no significant difference between control and placebo (MW U = 970, p = 0.73). In the AUT test, fluency showed a trend for being higher in the placebo group than in the control group (MW U = 286, p = 0.056, Cohen's D = 0.43) (Fig 3).

755

586

4819709

Compared to surgery what was the result of Ultrasound‐guided foam sclerotherapy on Standing still for a long time (> 15 min ) without discomfort?

multiple_choice

Participants randomized to UGFS recalled being able to carry out 13 of the 15 behaviours significantly more quickly than those randomized to surgery (Table 2 ).

756

1213

5397544

Compared to Low-molecular-weight heparin only before the surgery what was the result of Low-molecular-weight heparin before and after the surgery on Maximum amplitude values?

multiple_choice

There were no significant changes in α-angle and maximum amplitude values during or after laparoscopic fundoplication in both groups

757

1219

5741263

Compared to Placebo what was the result of Amplitude training on Stroke duration?

multiple_choice

the current results showed increases in stroke duration and normalized jerk after amplitude training, which were absent in the placebo group

758

1223

3917123

Compared to Placebo what was the result of Acupressure on Fatigue score in the sensory dimension?

multiple_choice

Post-hoc Duncan test showed that in the study group, total score of fatigue and score of fatigue in emotional, cognitive, and behavioral dimensions were significantly less than in the two groups of placebo and control after intervention (P < 0.05), but there was no significant difference between the control and placebo groups (P > 0.05).

759

1225

3917123

Compared to Placebo what was the result of Routine unit care on Fatigue score in the sensory dimension?

multiple_choice

Post-hoc Duncan test showed that in the study group, total score of fatigue and score of fatigue in emotional, cognitive, and behavioral dimensions were significantly less than in the two groups of placebo and control after intervention (P < 0.05), but there was no significant difference between the control and placebo groups (P > 0.05).

760

1226

4996255

Compared to HandiHaler® what was the result of ElliptaTM DPI on the number of steps to use, time taken to use and ease of use?

multiple_choice

In the combined analyses from the two Phase IIIa active comparator studies, patients declared a preference for the ElliptaTM DPI compared with the HandiHaler® in relation to the number of steps to use (59% vs 17%), time taken to use (62% vs 14%) and ease of use (63% vs 15%), although 22%–24% of all patients declared no preference for either inhaler (Table 4).

761

1233

5506592

Compared to baseline what was the result of education and mobilisation activities on the proportion of households who purchased anti-mosquito products in the last month?

multiple_choice

The mean expenditure on the products, among those households who bought them, was USD6.43; 30.4% in the intervention clusters and 36.7% in the control clusters spent more than this (difference − 0.06, 95% CIca −0.12 to −0.01).

762

1237

5228611

Compared to stay on their baseline regimen what was the result of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) 150/150/200/10 mg plus DRV 800 mg (Janssen) once daily on eGFR?

multiple_choice

Participants in the E/C/F/TAF plus DRV group had a higher rate of any adverse events [92% (n = 82) vs. 78% (n = 36)].

763

1238

5228611

Compared to stay on their baseline regimen what was the result of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) 150/150/200/10 mg plus DRV 800 mg (Janssen) once daily on quantitative proteinuria (urine protein-to-creatinine ratio) and tubular proteinuria (retinol binding protein-to-creatinine ratio and beta 2 microglobulin-to-creatinine ratio)?

multiple_choice

Participants in the E/C/F/TAF plus DRV group had a higher rate of any adverse events [92% (n = 82) vs. 78% (n = 36)].

764

1240

5228611

Compared to stay on their baseline regimen what was the result of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) 150/150/200/10 mg plus DRV 800 mg (Janssen) once daily on HIV-1 RNA <50 copies per mililiter at week 24;?

multiple_choice

Participants in the E/C/F/TAF plus DRV group had a higher rate of any adverse events [92% (n = 82) vs. 78% (n = 36)].

765

1243

3466198

Compared to hydroxyethylcellulose (HEC) placebo gel twice daily for 14 consecutive days what was the result of Acidform twice daily for 14 consecutive days on The median vaginal and cervical pH?

multiple_choice

There were no significant changes in the number of women with detectable L. crispatus or L. jensenii or in the concentrations of bacteria recovered by PCR in the Acidform or HEC group following 14 days of twice daily gel use (Table 4).

766

1245

3466198

Compared to hydroxyethylcellulose (HEC) placebo gel twice daily for 14 consecutive days what was the result of Acidform twice daily for 14 consecutive days on CVL concentrations of lactoferrin and interleukin-1 receptor antagonist (IL-1ra), an anti-inflammatory protein,?

multiple_choice

There were no significant changes in the number of women with detectable L. crispatus or L. jensenii or in the concentrations of bacteria recovered by PCR in the Acidform or HEC group following 14 days of twice daily gel use (Table 4).

767

1250

5225191

Compared to placebo pill what was the result of amitriptyline on GASE-AD (antidepressant-specific side effects)?

multiple_choice

We observed no differences between the groups in either the GASE-generic or GASE-generic-MA (multivariate analyses: group effect F (2, 36) = 1.89, p = .166; time effect F (4, 34) = 2.83, p = .040; group × time interaction effect F (4, 34) = 2.19, p = .091; univariate analyses regarding GASE-generic-MA: time effect F (0.60, 22.20) = 5.43, p = .027).

768

1255

4864053

Compared to placebo (starch) what was the result of MSD, 100 mg l?dopa plus 25 mg carbidopa on mean decrease in [11C]Ro15?4513 BP?

multiple_choice

The BP of the GABA ligand decreased significantly with l‐dopa in the medial prefrontal/anterior cingulate and right insula regions (by 18%, t = −3.63 P = 0.0054, and 18%, t = 3.85 P = 0039, respectively), with no significant effect in the other regions.

769

1264

3933059

Compared to baseline what was the result of Pomegranate juice (PJ) on Systolic blood pressure (SBP), diastolic blood pressure (DBP)?

multiple_choice

Comparison of pre- vs. post-trial values revealed a significant reduction in both SBP (P = 0.013) and DBP (P = 0.010), amounting to an approximate reduction by 7% and 6%, respectively.

770

1265

3933059

Compared to baseline what was the result of Pomegranate juice (PJ) on flow-mediated dilation (FMD)?

multiple_choice

Comparison of pre- vs. post-trial values revealed a significant reduction in both SBP (P = 0.013) and DBP (P = 0.010), amounting to an approximate reduction by 7% and 6%, respectively.

771

1269

3655855

Compared to safflower oil placebo for 4 weeks what was the result of 1.7 g of Long chain omega-3 fatty acids from fish oils (O3) per day for 4 weeks on central pulse wave velocity, augmentation index, aortic systolic blood pressure, BMI, waist, total cholesterol, serum glucose, IL-8, and IL-10,CRP ?

multiple_choice

Figure 1 shows the effect of O3 dosing for four weeks on plasma phospholipid EPA and DHA. Plasma levels increased significantly (p < 0.001).

772

1278

3585965

Compared to GLPG0259 what was the result of GLPG0259 and methotrexate on the rate of absorption of methotrexate?

multiple_choice

Regarding GLPG0259, co-administration of methotrexate 7.5 mg did not significantly alter the rate and extent of absorption of GLPG0259, with point estimates for Cmax and AUC24h of 102.67% and 102.11%, respectively.

773

1280

5928476

Compared to ProRoot MTA or Biodentine calcium silicate cements what was the result of SureFil SDR or EverX Posterior bulk-fill composite resins' bond on bulk-fill composite resin values and calcium silicate cement values?

multiple_choice

However, there were no significant differences between bulk-fill composite resin values and calcium silicate cement values (P>0.05).

774

1281

4132637

Compared to clopidogrel what was the result of ticagrelor on The incidence of the primary composite endpoint?

multiple_choice

whereas stroke incidence did not differ significantly between treatment arms (1.3 vs. 1.4%; HR 0.95; 95% CI 0.69–1.33; P = 0.79).

775

1287

4132637

Compared to clopidogrel what was the result of ticagrelor on non-CABG-related major bleeding?

multiple_choice

whereas stroke incidence did not differ significantly between treatment arms (1.3 vs. 1.4%; HR 0.95; 95% CI 0.69–1.33; P = 0.79).

776

1293

3636800

Compared to completing 6 days of assessment (four sets of questions per day) with the SMS text-only implementation what was the result of completing 6 days of assessment (four sets of questions per day) with a native smartphone application on the total quantitative feedback score?

multiple_choice

A greater proportion of data points were completed with the native smartphone application in comparison to the SMS text-only implementation (β = -.25, SE=.11, P=.02), which also took significantly less time to complete (β =.78, SE= .09, P<.001).

777

1298

5951568

Compared to control what was the result of provided with written information about the electrodiagnostic testing on Overall pain scores?

multiple_choice

Overall pain scores between the intervention (20.91±2.33mm) and non-intervention group (25.30±2.44mm) in the NCS cohort did not differ significantly (p = 0.15).

778

1310

3258678

Compared to 78-week treatment with placebo what was the result of 78-week treatment with tramiprosate 150 mg BID on hippocampus volume (HV) change?

multiple_choice

These adjusted models showed a trend toward a treatment effect for ADAS-cog (P = 0.098) and indicated significantly less HV loss for tramiprosate 100 mg (P = 0.035) and 150 mg (P = 0.009) compared to placebo.

779

1312

3258678

Compared to 78-week treatment with placebo what was the result of 78-week treatment with tramiprosate 100 mg or tramiprosate 150 mg BID on Alzheimer Disease Assessment Scale – cognitive subscale (ADAS-cog)?

multiple_choice

These adjusted models showed a trend toward a treatment effect for ADAS-cog (P = 0.098) and indicated significantly less HV loss for tramiprosate 100 mg (P = 0.035) and 150 mg (P = 0.009) compared to placebo.

780

1333

3917204

Compared to received scaling and root planing with hand instruments what was the result of received treatment with rotary instruments on Clinical improvement in multi-rooted teeth ?

multiple_choice

At deep pocket site (initial PD > 6 mm), in the rotary instrument group, PD reduced from 7.2 ± 1.5 to 6.5 ± 1.8 and in the Gracey curette group, it reduced from 6.7 ± 0.9 to 5.4 ± 1.8. But while comparing these two groups, the results were statistically nonsignificant. Similarly, other clinical parameters like GR and CAL gave statistically nonsignificant results [Table 3].

781

1335

5673730

Compared to insulin 0.8-0.9 mg/kg/day in two divided doses subcutaneously (Group-B) what was the result of oral metformin 500 mg TDS (Group-A) on numbers of babies were delivered after 38 weeks of pregnancy?

multiple_choice

There were two intrauterine deaths and significantly higher HbA1C at term in Group-B. (P=0.03).

782

1340

4012222

Compared to baseline what was the result of lower limb neuromuscular electrical stimulation (NMES) applied daily to both quadriceps muscles for six weeks. on Global performance status and STS?

multiple_choice

Global performance status and STS appeared somewhat better, but these changes did not achieve statistical significance (Fisher's exact test p = 0.15 comparing categories of PS; mean reduction in STS = −1.2s, P = 0.3).

783

1343

5320660

Compared to muffins enriched with 0 g HAM-RS2 (control) what was the result of muffins enriched with 30 g HAM-RS2 on Mean overall satiety score?

multiple_choice

Mean overall satiety score did not differ within or between groups (P = 0.230).

784

1359

3842830

Compared to Placebo what was the result of Istradefylline 20 mg or 40 mg on Daily OFF time?

multiple_choice

No differences were observed among the groups for other secondary efficacy variables.

785

1364

4365564

Compared to ALIF with BAK cages what was the result of Charité artificial disc on Complications related to approach method?

multiple_choice

The rate of major neurological complications was similar between the 2 groups (investigational = 4.4%, control = 4.0%)

786

1370

5285426

Compared to Laparoscopic surgery what was the result of Robotic surgery on Urological function scores in females?

multiple_choice

Overall, there was no statistical difference between the mean change of scores from baseline between the two groups in any of the FSF components or the FSF composite scores.

787

1372

5285426

Compared to Laparoscopic surgery what was the result of Robotic surgery on Male sexual function scores?

multiple_choice

Overall, there was no statistical difference between the mean change of scores from baseline between the two groups in any of the FSF components or the FSF composite scores.

788

1374

3628658

Compared to Supine position what was the result of Lateral decubitus position on Hospital stay?

multiple_choice

The hospital stay, operating time, intraoperative blood loss, length of incision, X-ray fluoroscopy time, and out-of-bed activity time in the lateral decubitus position group were significantly lower than those in the supine position group.

789

1375

3628658

Compared to Supine position what was the result of Lateral decubitus position on Loss of blood during surgery?

multiple_choice

The hospital stay, operating time, intraoperative blood loss, length of incision, X-ray fluoroscopy time, and out-of-bed activity time in the lateral decubitus position group were significantly lower than those in the supine position group.

790

1377

3628658

Compared to Supine position what was the result of Lateral decubitus position on Surgery time?

multiple_choice

The hospital stay, operating time, intraoperative blood loss, length of incision, X-ray fluoroscopy time, and out-of-bed activity time in the lateral decubitus position group were significantly lower than those in the supine position group.

791

1378

3628658

Compared to Supine position what was the result of Lateral decubitus position on Harris hip values and union time of fractures?

multiple_choice

The hospital stay, operating time, intraoperative blood loss, length of incision, X-ray fluoroscopy time, and out-of-bed activity time in the lateral decubitus position group were significantly lower than those in the supine position group.

792

1380

4659198

Compared to Phototherapy only what was the result of Phototherapy plus massage on Bilirubin levels after 3 days?

multiple_choice

On the third day, the massage group showed significantly higher defecation frequency (p = 0.045) and significantly lower bilirubin levels (p = 0.03) compared with the control group

793

1383

4659198

Compared to Phototherapy only what was the result of Phototherapy plus massage on Baseline medical characteristics?

multiple_choice

On the third day, the massage group showed significantly higher defecation frequency (p = 0.045) and significantly lower bilirubin levels (p = 0.03) compared with the control group

794

1393

4599543

Compared to received saline solution (placebo) what was the result of received fibrinogen concentrate on postoperative bleeding?

multiple_choice

At the arrival in the ICU, patients in the treatment arm had significantly higher levels of fibrinogen, as measured by the central laboratory.

795

1394

5724392

Compared to transfusions what was the result of hydroxyurea on transcranial Doppler (TCD) flow velocities?

multiple_choice

The final model-based TCD velocities (mean ± standard error) on the Standard Arm versus Alternative Arm were 143 ± 1.6 and 138 ± 1.6 cm/sec, respectively, with difference (95% CI) = 4.54 (0.10, 8.98), non-inferiority p=8.82 × 10−16 and a post-hoc superiority p=0.023. The planned per-protocol analysis excluding study participants who exited the study early showed almost identical findings, with difference = 5.06 (0.56, 9.57), non-inferiority p=1.05 × 10−15 and a post-hoc superiority p=0.015. An age-adjusted analysis gave almost identical findings (not shown).

796

1428

5553001

Compared to wait-list control condition what was the result of Internet-based guided self-help program, including weekly support from a therapist via encrypted email on PTSD-Checklist-Civilian version (PCL-C) difference ?

multiple_choice

The model difference at postassessment was 3.91 points on the BDI-II in favor of the intervention group, representing a medium effect size. The model difference at follow-up was 9.41 points on the BDI-II, representing a large effect size. For BAI, a linear model provided best fit to the data (see Multimedia Appendix 3). At preassessment, the intervention group reported a significantly higher level of symptoms; the model difference was 5.11 points on the BAI. The intervention group exhibited a significant decline over time, whereas the control group exhibited a significant increase in symptoms over time. At postassessment, there was no difference between the groups. However, at follow-up there was a difference of 6.99 points on the BAI in favor of the intervention group, representing a large effect size

797

1430

5566825

Compared to cup of milk only twice a day while continuing with their normal/routine diet. what was the result of receive orally daily either CyavanaprÄ?Å›a (CP) (approx. 6 g) followed by a cup of milk (100 – 200 ml) on total duration of illnesses?

multiple_choice

A total of 540 participants had episodes of infection/allergy related to immunity. Of these, 254 participants (47.03%) participants were in CP group while 286 (52.96%) were in the control group. The difference observed was statistically not significant (P > 0.05).

798

1434

5566825

Compared to cup of milk only twice a day while continuing with their normal/routine diet. what was the result of receive orally daily either CyavanaprÄ?Å›a (CP) (approx. 6 g) followed by a cup of milk (100 – 200 ml) on CGI-I scale improvement?

multiple_choice

A total of 540 participants had episodes of infection/allergy related to immunity. Of these, 254 participants (47.03%) participants were in CP group while 286 (52.96%) were in the control group. The difference observed was statistically not significant (P > 0.05).

799

1435

5336430

Compared to vehicle what was the result of 5-fluorouracil (5-FU) 0.5%/salicylic acid 10% on The percentage of patients with complete clinical clearance (CCC) 8 weeks after the end of treatment (primary endpoint)?

multiple_choice

The proportional reduction from baseline in the total number of AK lesions per patient was significantly greater with 5-FU 0.5%/salicylic acid 10% than with vehicle: 78.0% versus 46.9%, respectively; P < 0.0001 (Fig. 5).