README.md

metadata

library_name: popV
license: cc-by-4.0
tags:
  - biology
  - genomics
  - single-cell
  - anndata_version:0.11.3
  - python_version:3.11.11
  - popV
  - 'tissue: diverse'

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Tabula Sapiens is a benchmark, first-draft human cell atlas of over 1.1M cells from 28 organs of 24 normal human subjects. This work is the product of the Tabula Sapiens Consortium. Taking the organs from the same individual controls for genetic background, age, environment, and epigenetic effects, and allows detailed analysis and comparison of cell types that are shared between tissues.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	11340	0.99	0.99	0.99	0.99	0.00	0.98	0.98	0.98	0.99
CD4-positive, alpha-beta T cell	9623	0.58	0.78	0.82	0.73	0.00	0.34	0.44	0.53	0.78
fibroblast	8327	0.79	0.78	0.93	0.70	0.00	0.59	0.71	0.67	0.88
CD8-positive, alpha-beta T cell	7597	0.71	0.77	0.81	0.73	0.00	0.72	0.59	0.61	0.80
neutrophil	6941	0.94	0.97	0.97	0.97	0.00	0.94	0.95	0.92	0.98
macrophage	6962	0.77	0.84	0.93	0.81	0.00	0.77	0.73	0.70	0.89
stromal cell of ovary	3562	0.95	0.93	0.92	0.63	0.00	0.08	0.96	0.93	0.97
endothelial cell	3356	0.74	0.74	0.91	0.64	0.00	0.66	0.68	0.64	0.83
basal cell	3382	0.89	0.86	0.88	0.70	0.00	0.70	0.86	0.84	0.93
plasma cell	2799	0.98	0.98	0.97	0.98	0.00	0.98	0.98	0.97	0.99
bladder urothelial cell	2795	0.98	0.97	0.97	0.70	0.00	0.51	0.98	0.96	0.99
monocyte	2521	0.46	0.38	0.77	0.46	0.00	0.35	0.48	0.50	0.60
mesenchymal stem cell	2365	0.88	0.76	0.90	0.51	0.00	0.21	0.90	0.82	0.93
smooth muscle cell	1776	0.71	0.67	0.88	0.69	0.00	0.67	0.73	0.72	0.81
classical monocyte	1787	0.60	0.61	0.76	0.46	0.00	0.50	0.55	0.62	0.69
luminal epithelial cell of mammary gland	1536	0.99	0.05	0.96	0.66	0.00	0.64	0.97	0.95	0.99
capillary endothelial cell	1527	0.71	0.65	0.87	0.59	0.00	0.61	0.67	0.66	0.79
erythrocyte	1404	0.98	0.97	0.95	0.97	0.00	0.96	0.96	0.96	0.98
natural killer cell	1462	0.73	0.75	0.75	0.70	0.00	0.69	0.69	0.71	0.76
enterocyte of epithelium proper of duodenum	1367	0.90	0.50	0.81	0.57	0.00	0.56	0.89	0.87	0.95
stratified squamous epithelial cell	1237	0.84	0.79	0.87	0.71	0.00	0.70	0.84	0.83	0.89
acinar cell of salivary gland	1220	0.95	0.84	0.93	0.77	0.00	0.72	0.92	0.89	0.96
pulmonary alveolar type 2 cell	1158	0.96	0.96	0.97	0.88	0.00	0.91	0.96	0.94	0.97
conjunctival epithelial cell	1061	0.93	0.71	0.86	0.45	0.00	0.02	0.94	0.90	0.94
pericyte	1121	0.63	0.57	0.83	0.60	0.00	0.55	0.67	0.65	0.75
luminal cell of prostate epithelium	1056	0.90	0.84	0.93	0.76	0.00	0.54	0.95	0.92	0.95
cardiac endothelial cell	1000	0.93	0.88	0.93	0.59	0.00	0.11	0.95	0.89	0.96
naive thymus-derived CD4-positive, alpha-beta T cell	1004	0.23	0.04	0.32	0.05	0.00	0.26	0.22	0.29	0.30
kidney epithelial cell	974	0.98	0.93	0.94	0.76	0.00	0.63	0.99	0.97	0.99
hepatocyte	703	0.99	0.99	0.97	0.83	0.00	0.62	0.99	0.98	1.00
blood vessel smooth muscle cell	666	0.71	0.52	0.90	0.59	0.00	0.10	0.88	0.81	0.91
enterocyte of epithelium proper of ileum	666	0.96	0.00	0.76	0.34	0.00	0.35	0.98	0.95	0.97
T cell	626	0.45	0.23	0.55	0.15	0.00	0.19	0.31	0.38	0.54
mast cell	600	0.88	0.84	0.94	0.86	0.00	0.91	0.89	0.90	0.93
skeletal muscle satellite stem cell	644	0.95	0.93	0.95	0.84	0.00	0.86	0.95	0.88	0.96
regular atrial cardiac myocyte	572	0.81	0.63	0.83	0.28	0.00	0.02	0.88	0.90	0.93
intermediate monocyte	547	0.37	0.15	0.56	0.25	0.00	0.28	0.37	0.43	0.50
pancreatic acinar cell	577	0.96	0.19	0.93	0.50	0.00	0.05	0.98	0.95	0.98
mature NK T cell	550	0.46	0.45	0.53	0.42	0.00	0.42	0.38	0.45	0.59
mononuclear phagocyte	509	0.38	0.00	0.90	0.16	0.00	0.05	0.69	0.50	0.70
fibroblast of breast	535	0.95	0.00	0.97	0.35	0.00	0.28	0.84	0.72	0.95
vascular associated smooth muscle cell	502	0.62	0.05	0.73	0.17	0.00	0.27	0.60	0.62	0.66
vein endothelial cell	450	0.41	0.17	0.73	0.30	0.00	0.37	0.45	0.46	0.59
CD4-positive, alpha-beta thymocyte	487	0.37	0.00	0.60	0.38	0.00	0.39	0.40	0.34	0.60
enterocyte of epithelium of large intestine	453	0.77	0.29	0.58	0.34	0.00	0.49	0.80	0.80	0.80
myofibroblast cell	439	0.63	0.22	0.82	0.46	0.00	0.46	0.57	0.60	0.77
thymic fibroblast type 2	405	0.56	0.00	0.71	0.15	0.00	0.07	0.69	0.57	0.58
corneal epithelial cell	479	0.94	0.01	0.93	0.68	0.00	0.49	0.96	0.94	0.97
spermatid	376	0.96	0.00	0.96	0.70	0.00	0.87	0.99	0.96	0.99
duct epithelial cell	383	0.76	0.57	0.82	0.44	0.00	0.29	0.83	0.74	0.85
mesenchymal stem cell of adipose tissue	369	0.24	0.00	0.63	0.34	0.00	0.28	0.34	0.34	0.49
basal cell of prostate epithelium	353	0.71	0.09	0.90	0.50	0.00	0.39	0.87	0.76	0.86
endothelial cell of artery	373	0.53	0.39	0.75	0.44	0.00	0.49	0.58	0.56	0.68
stromal cell	345	0.58	0.04	0.53	0.27	0.00	0.19	0.77	0.73	0.85
thymic fibroblast type 1	337	0.04	0.01	0.84	0.23	0.00	0.23	0.64	0.46	0.60
pulmonary alveolar type 1 cell	340	0.97	0.94	0.95	0.90	0.00	0.92	0.97	0.91	0.97
spermatocyte	343	0.94	0.00	0.94	0.71	0.00	0.65	0.98	0.95	0.98
pancreatic ductal cell	271	0.90	0.56	0.90	0.76	0.00	0.64	0.95	0.92	0.95
regulatory T cell	274	0.18	0.01	0.26	0.14	0.00	0.23	0.34	0.35	0.43
ventricular cardiac muscle cell	263	0.44	0.05	0.73	0.31	0.00	0.41	0.78	0.81	0.83
endothelial cell of lymphatic vessel	233	0.65	0.51	0.87	0.50	0.00	0.51	0.59	0.57	0.68
hematopoietic precursor cell	209	0.52	0.67	0.72	0.61	0.00	0.52	0.49	0.54	0.68
retinal blood vessel endothelial cell	213	0.11	0.01	0.78	0.13	0.00	0.09	0.64	0.51	0.54
small intestine goblet cell	200	0.88	0.58	0.88	0.56	0.00	0.57	0.95	0.88	0.93
gamma-delta T cell	201	0.30	0.09	0.59	0.23	0.00	0.45	0.68	0.48	0.71
fibroblast of cardiac tissue	195	0.96	0.54	0.90	0.07	0.00	0.32	0.77	0.70	0.95
paneth cell of epithelium of small intestine	191	0.51	0.47	0.72	0.31	0.00	0.46	0.59	0.66	0.78
club cell	172	0.84	0.73	0.85	0.54	0.00	0.79	0.83	0.72	0.87
intestinal crypt stem cell of colon	179	0.73	0.63	0.57	0.45	0.00	0.37	0.80	0.77	0.82
progenitor cell of mammary luminal epithelium	169	0.98	0.00	0.99	0.97	0.00	0.94	0.96	0.88	0.98
epithelial cell	163	0.92	0.63	0.96	0.36	0.00	0.62	0.92	0.89	0.93
basophil	160	0.52	0.06	0.90	0.40	0.00	0.71	0.69	0.74	0.80
large intestine goblet cell	132	0.82	0.67	0.82	0.38	0.00	0.56	0.92	0.84	0.90
eye photoreceptor cell	138	0.90	0.88	0.91	0.95	0.00	0.89	0.95	0.96	0.96
epithelial cell of uterus	143	0.95	0.42	0.92	0.24	0.00	0.56	0.93	0.87	0.97
enterocyte of epithelium proper of small intestine	149	0.33	0.01	0.63	0.17	0.00	0.42	0.53	0.57	0.72
tissue-resident macrophage	116	0.53	0.00	0.82	0.33	0.00	0.24	0.37	0.40	0.66
acinar cell	120	0.84	0.56	0.89	0.81	0.00	0.87	0.88	0.85	0.94
non-classical monocyte	122	0.27	0.34	0.31	0.04	0.00	0.33	0.38	0.31	0.49
lung ciliated cell	119	0.79	0.42	0.96	0.77	0.00	0.82	0.91	0.88	0.94
activated CD8-positive, alpha-beta T cell	103	0.21	0.02	0.67	0.03	0.00	0.08	0.31	0.23	0.54
alveolar adventitial fibroblast	106	0.71	0.10	0.84	0.25	0.00	0.54	0.76	0.66	0.82
naive thymus-derived CD8-positive, alpha-beta T cell	112	0.16	0.00	0.45	0.00	0.00	0.17	0.14	0.14	0.42
adventitial cell	91	0.18	0.00	0.62	0.06	0.00	0.13	0.21	0.31	0.49
respiratory goblet cell	114	0.60	0.54	0.82	0.58	0.00	0.69	0.61	0.64	0.78
theca cell	118	0.54	0.00	0.75	0.62	0.00	0.73	0.73	0.59	0.77
myeloid leukocyte	96	0.16	0.00	0.70	0.21	0.00	0.08	0.21	0.20	0.60
keratocyte	112	0.12	0.02	0.53	0.11	0.00	0.02	0.50	0.38	0.23
enteroglial cell	105	0.85	0.68	0.97	0.79	0.00	0.84	0.95	0.83	0.92
innate lymphoid cell	89	0.16	0.11	0.27	0.25	0.00	0.18	0.15	0.19	0.27
erythroid progenitor cell	94	0.59	0.63	0.68	0.58	0.00	0.67	0.68	0.66	0.75
myometrial cell	100	0.65	0.00	0.74	0.39	0.00	0.37	0.69	0.57	0.78
endothelial cell of vascular tree	85	0.42	0.02	0.60	0.28	0.00	0.37	0.53	0.38	0.65
hematopoietic stem cell	76	0.71	0.65	0.74	0.72	0.00	0.68	0.76	0.68	0.80
salivary gland cell	77	0.50	0.00	0.81	0.47	0.00	0.49	0.60	0.56	0.84
granulocyte	84	0.24	0.00	0.51	0.25	0.00	0.23	0.31	0.17	0.61
CD8-positive, alpha-beta thymocyte	82	0.19	0.02	0.40	0.27	0.00	0.27	0.29	0.25	0.52
ciliated columnar cell of tracheobronchial tree	81	0.58	0.15	0.94	0.73	0.00	0.64	0.93	0.86	0.94
intrahepatic cholangiocyte	73	0.97	0.12	0.95	0.60	0.00	0.60	0.97	0.89	0.97
mural cell	58	0.29	0.16	0.86	0.12	0.00	0.30	0.62	0.39	0.74
intestinal crypt stem cell of small intestine	61	0.13	0.24	0.26	0.15	0.00	0.23	0.36	0.38	0.44
activated CD4-positive, alpha-beta T cell	51	0.03	0.00	0.32	0.06	0.00	0.08	0.09	0.08	0.17
myeloid dendritic cell	68	0.20	0.18	0.40	0.22	0.00	0.19	0.16	0.16	0.31
Mueller cell	45	0.56	0.46	0.56	0.72	0.00	0.55	0.80	0.81	0.82
fast muscle cell	45	0.68	0.57	0.90	0.71	0.00	0.73	0.72	0.77	0.87
platelet	54	0.91	0.88	0.92	0.90	0.00	0.69	0.91	0.73	0.86
myoepithelial cell	49	0.47	0.30	0.82	0.52	0.00	0.39	0.61	0.38	0.77
common myeloid progenitor	48	0.47	0.48	0.72	0.38	0.00	0.53	0.52	0.60	0.65
thymocyte	42	0.00	0.00	0.34	0.36	0.00	0.17	0.18	0.19	0.75
intestinal tuft cell	53	0.80	0.75	0.93	0.70	0.00	0.87	0.93	0.94	0.91
pancreatic stellate cell	46	0.00	0.00	0.88	0.21	0.00	0.11	0.77	0.35	0.65
tendon cell	43	0.12	0.09	0.42	0.20	0.00	0.47	0.45	0.30	0.57
microglial cell	41	0.09	0.00	0.66	0.04	0.00	0.09	0.25	0.13	0.33
muscle cell	39	0.77	0.00	0.95	0.86	0.00	0.58	0.82	0.90	0.95
enterocyte of epithelium proper of jejunum	33	0.00	0.00	0.08	0.19	0.00	0.04	0.39	0.25	0.34
mesothelial cell	41	0.64	0.65	0.92	0.71	0.00	0.47	0.78	0.71	0.73
colon endothelial cell	33	0.00	0.00	0.61	0.00	0.00	0.00	0.28	0.24	0.29
colon macrophage	29	0.18	0.00	0.73	0.21	0.00	0.08	0.31	0.15	0.75
serous cell of epithelium of trachea	33	0.34	0.00	0.74	0.34	0.00	0.15	0.34	0.45	0.74
ciliated epithelial cell	29	0.86	0.04	0.89	0.58	0.00	0.64	0.97	0.86	0.93
Schwann cell	28	0.58	0.47	0.67	0.57	0.00	0.49	0.71	0.58	0.74
mucus secreting cell	37	0.63	0.07	0.79	0.50	0.00	0.46	0.63	0.68	0.84
supporting cell of vestibular epithelium	27	0.79	0.00	0.63	0.65	0.00	0.12	0.98	0.81	0.93
enteroendocrine cell of small intestine	27	0.72	0.11	0.80	0.63	0.00	0.81	0.85	0.74	0.87
ovarian surface epithelial cell	24	0.38	0.31	0.85	0.41	0.00	0.42	0.84	0.60	0.69
transit amplifying cell of colon	33	0.73	0.47	0.42	0.18	0.00	0.25	0.58	0.51	0.83
glandular epithelial cell	23	0.69	0.12	0.74	0.37	0.00	0.15	0.79	0.59	0.88
melanocyte	26	0.61	0.41	0.68	0.45	0.00	0.38	0.80	0.65	0.89
tracheal goblet cell	19	0.60	0.18	0.57	0.53	0.00	0.63	0.68	0.45	0.78
hepatic stellate cell	29	0.60	0.00	0.60	0.05	0.00	0.23	0.62	0.47	0.73
bronchial smooth muscle cell	27	0.11	0.00	0.54	0.11	0.00	0.32	0.42	0.31	0.42
paneth cell of colon	31	0.00	0.05	0.52	0.47	0.00	0.19	0.63	0.37	0.69
tongue muscle cell	24	0.34	0.00	0.83	0.08	0.00	0.16	0.65	0.36	0.74
leukocyte	11	0.09	0.00	0.03	0.00	0.00	0.07	0.05	0.05	0.10
tuft cell of colon	23	0.00	0.19	0.77	0.45	0.00	0.60	0.90	0.83	0.77
slow muscle cell	9	0.00	0.06	0.74	0.30	0.00	0.42	0.90	0.67	0.80
ionocyte	16	0.71	0.13	0.55	0.62	0.00	0.61	0.86	0.70	0.90
connective tissue cell	19	0.00	0.00	0.91	0.00	0.00	0.08	0.48	0.22	0.52
sebum secreting cell	16	0.00	0.02	0.81	0.10	0.00	0.24	0.81	0.49	0.86
neuro-medullary thymic epithelial cell	14	0.24	0.42	0.52	0.29	0.00	0.20	0.30	0.44	0.34
endothelial cell of arteriole	18	0.00	0.00	0.88	0.00	0.00	0.00	0.67	0.35	0.20
male germ cell	13	0.79	0.00	0.67	0.00	0.00	0.67	0.92	0.65	0.88
type B pancreatic cell	15	0.83	0.00	0.89	0.54	0.00	0.71	0.97	0.80	1.00
hematopoietic cell	8	0.00	0.00	0.40	0.46	0.00	0.11	0.41	0.39	0.71
plasmacytoid dendritic cell	8	0.33	0.00	0.50	0.14	0.00	0.03	0.45	0.18	0.44
neuron	6	0.00	0.00	1.00	0.36	0.00	0.06	0.67	0.67	0.92
myeloid cell	9	0.00	0.00	0.00	0.00	0.00	0.00	0.30	0.20	0.00
myo-medullary thymic epithelial cell	7	0.50	0.00	0.86	0.60	0.00	0.17	0.53	0.62	0.71
Langerhans cell	8	0.39	0.00	0.40	0.14	0.00	0.10	0.20	0.24	0.45
interstitial cell of Cajal	8	0.00	0.00	1.00	0.35	0.00	0.09	0.57	0.57	1.00
peritubular myoid cell	6	0.00	0.00	0.80	0.00	0.00	0.00	0.41	0.32	0.44
retinal pigment epithelial cell	5	0.00	0.00	0.50	0.55	0.00	0.53	1.00	0.77	1.00
spermatogonium	12	0.00	0.00	0.67	0.40	0.00	0.24	0.96	0.85	0.80
retinal bipolar neuron	6	0.00	0.50	0.25	0.50	0.00	0.62	0.71	0.83	0.91
endothelial cell of venule	3	0.00	0.00	0.67	0.00	0.00	0.09	0.80	0.29	0.80
vestibular dark cell	7	0.00	0.00	0.25	0.25	0.00	0.23	1.00	0.80	0.83
pancreatic A cell	2	0.00	0.00	1.00	0.00	0.00	0.80	1.00	1.00	1.00
type L enteroendocrine cell	6	0.00	0.00	0.25	0.29	0.00	0.16	0.92	0.71	0.80
medullary thymic epithelial cell	3	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
adipocyte	2	0.00	0.00	0.80	0.00	0.00	0.00	0.50	0.20	1.00
transit amplifying cell of small intestine	1	0.00	0.00	0.00	0.00	0.00	0.04	0.33	0.00	0.00
taste receptor cell	4	0.00	0.00	0.67	0.00	0.00	0.12	0.40	0.27	0.57
enterochromaffin-like cell	3	0.00	0.00	0.33	0.40	0.00	0.86	1.00	0.80	0.80
enteroendocrine cell	2	0.00	0.14	0.67	0.50	0.00	0.09	0.67	0.67	0.80
pulmonary ionocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
glial cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.25	0.00
oocyte	1	0.00	0.03	1.00	0.50	0.00	0.07	1.00	0.67	0.67
serous cell of epithelium of bronchus	2	0.00	0.00	0.00	0.00	0.00	0.25	1.00	0.40	0.00
radial glial cell	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Leydig cell	3	0.00	0.00	0.00	0.00	0.00	0.00	0.29	0.33	0.00
pancreatic D cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
T follicular helper cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
retina horizontal cell	2	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pancreatic PP cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
epithelial fate stem cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
mesenchymal cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
erythroid lineage cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
retinal ganglion cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
B cell	103155	0.99	0.99	0.99	0.99	0.00	0.98	0.98	0.98	0.99
CD4-positive, alpha-beta T cell	87505	0.58	0.78	0.87	0.82	0.00	0.43	0.45	0.53	0.82
fibroblast	75007	0.79	0.73	0.97	0.83	0.00	0.84	0.70	0.67	0.92
CD8-positive, alpha-beta T cell	68678	0.71	0.77	0.87	0.82	0.00	0.70	0.59	0.61	0.82
neutrophil	62597	0.95	0.97	0.98	0.97	0.00	0.95	0.95	0.92	0.98
macrophage	62108	0.77	0.83	0.95	0.87	0.00	0.78	0.74	0.70	0.91
stromal cell of ovary	31441	0.95	0.65	0.94	0.85	0.00	0.96	0.96	0.94	0.98
endothelial cell	30345	0.74	0.69	0.96	0.82	0.00	0.88	0.69	0.65	0.92
basal cell	30144	0.89	0.78	0.94	0.81	0.00	0.85	0.86	0.84	0.94
plasma cell	24544	0.98	0.98	0.98	0.98	0.00	0.98	0.98	0.97	0.99
bladder urothelial cell	24446	0.98	0.97	0.98	0.81	0.00	0.88	0.98	0.96	0.99
monocyte	23231	0.47	0.30	0.86	0.70	0.00	0.59	0.50	0.53	0.72
mesenchymal stem cell	21132	0.87	0.65	0.95	0.69	0.00	0.94	0.89	0.82	0.96
smooth muscle cell	16649	0.73	0.64	0.93	0.84	0.00	0.84	0.75	0.74	0.88
classical monocyte	16413	0.59	0.54	0.84	0.73	0.00	0.67	0.58	0.63	0.77
luminal epithelial cell of mammary gland	13896	0.98	0.00	0.98	0.83	0.00	0.95	0.98	0.95	0.99
capillary endothelial cell	13769	0.73	0.56	0.93	0.80	0.00	0.82	0.69	0.69	0.86
erythrocyte	13207	0.97	0.96	0.98	0.98	0.00	0.96	0.96	0.96	0.97
natural killer cell	12769	0.72	0.73	0.83	0.80	0.00	0.71	0.69	0.70	0.76
enterocyte of epithelium proper of duodenum	12128	0.90	0.00	0.87	0.74	0.00	0.94	0.90	0.88	0.97
stratified squamous epithelial cell	11086	0.84	0.75	0.92	0.83	0.00	0.85	0.85	0.83	0.90
acinar cell of salivary gland	11017	0.95	0.75	0.97	0.89	0.00	0.95	0.93	0.91	0.97
pulmonary alveolar type 2 cell	10436	0.96	0.96	0.99	0.93	0.00	0.96	0.97	0.96	0.98
conjunctival epithelial cell	10025	0.94	0.71	0.91	0.66	0.00	0.91	0.95	0.91	0.96
pericyte	9763	0.62	0.48	0.90	0.77	0.00	0.72	0.67	0.66	0.81
luminal cell of prostate epithelium	9596	0.90	0.57	0.96	0.86	0.00	0.94	0.95	0.92	0.96
cardiac endothelial cell	9092	0.94	0.78	0.98	0.80	0.00	0.97	0.95	0.90	0.98
naive thymus-derived CD4-positive, alpha-beta T cell	8823	0.22	0.02	0.50	0.29	0.00	0.27	0.24	0.30	0.39
kidney epithelial cell	8304	0.98	0.06	0.97	0.86	0.00	0.94	0.99	0.97	0.99
hepatocyte	6711	0.99	0.98	0.97	0.90	0.00	0.95	0.99	0.97	1.00
blood vessel smooth muscle cell	5976	0.71	0.20	0.95	0.87	0.00	0.93	0.89	0.82	0.95
enterocyte of epithelium proper of ileum	5811	0.96	0.00	0.85	0.61	0.00	0.95	0.98	0.96	0.98
T cell	5663	0.45	0.16	0.70	0.43	0.00	0.34	0.35	0.41	0.64
mast cell	5620	0.89	0.84	0.97	0.93	0.00	0.96	0.90	0.92	0.96
skeletal muscle satellite stem cell	5524	0.96	0.93	0.98	0.93	0.00	0.95	0.95	0.89	0.97
regular atrial cardiac myocyte	5244	0.80	0.23	0.91	0.81	0.00	0.98	0.89	0.91	0.96
intermediate monocyte	4931	0.37	0.10	0.70	0.56	0.00	0.37	0.41	0.44	0.57
pancreatic acinar cell	4899	0.95	0.01	0.97	0.87	0.00	0.96	0.98	0.96	0.98
mature NK T cell	4844	0.47	0.41	0.69	0.59	0.00	0.46	0.39	0.47	0.63
mononuclear phagocyte	4827	0.42	0.00	0.96	0.52	0.00	0.72	0.73	0.53	0.92
fibroblast of breast	4735	0.96	0.00	0.99	0.70	0.00	0.88	0.85	0.73	0.98
vascular associated smooth muscle cell	4517	0.66	0.01	0.86	0.67	0.00	0.72	0.66	0.65	0.80
vein endothelial cell	4248	0.40	0.09	0.86	0.63	0.00	0.62	0.48	0.48	0.70
CD4-positive, alpha-beta thymocyte	4198	0.35	0.00	0.76	0.61	0.00	0.65	0.39	0.36	0.69
enterocyte of epithelium of large intestine	4114	0.78	0.22	0.74	0.62	0.00	0.86	0.83	0.85	0.85
myofibroblast cell	3997	0.67	0.15	0.91	0.73	0.00	0.68	0.60	0.61	0.87
thymic fibroblast type 2	3800	0.59	0.00	0.86	0.52	0.00	0.90	0.70	0.59	0.90
corneal epithelial cell	3707	0.93	0.00	0.95	0.83	0.00	0.93	0.95	0.93	0.96
spermatid	3633	0.96	0.00	0.99	0.92	0.00	0.96	0.99	0.97	0.99
duct epithelial cell	3506	0.75	0.38	0.91	0.72	0.00	0.86	0.84	0.75	0.90
mesenchymal stem cell of adipose tissue	3408	0.24	0.00	0.74	0.55	0.00	0.47	0.34	0.34	0.53
basal cell of prostate epithelium	3142	0.71	0.01	0.92	0.74	0.00	0.87	0.86	0.77	0.89
endothelial cell of artery	3098	0.52	0.28	0.84	0.67	0.00	0.69	0.62	0.57	0.80
stromal cell	3112	0.64	0.00	0.70	0.48	0.00	0.79	0.79	0.77	0.92
thymic fibroblast type 1	2933	0.02	0.00	0.91	0.52	0.00	0.69	0.67	0.51	0.86
pulmonary alveolar type 1 cell	2776	0.98	0.86	0.98	0.93	0.00	0.94	0.98	0.94	0.98
spermatocyte	2727	0.93	0.00	0.97	0.92	0.00	0.89	0.98	0.95	0.98
pancreatic ductal cell	2447	0.89	0.10	0.95	0.86	0.00	0.92	0.96	0.93	0.97
regulatory T cell	2375	0.17	0.01	0.45	0.32	0.00	0.26	0.36	0.35	0.48
ventricular cardiac muscle cell	2336	0.40	0.00	0.81	0.72	0.00	0.95	0.80	0.82	0.90
endothelial cell of lymphatic vessel	2205	0.66	0.49	0.94	0.74	0.00	0.75	0.67	0.63	0.79
hematopoietic precursor cell	1931	0.54	0.65	0.85	0.79	0.00	0.59	0.55	0.61	0.76
retinal blood vessel endothelial cell	1877	0.12	0.00	0.93	0.45	0.00	0.87	0.68	0.53	0.90
small intestine goblet cell	1844	0.85	0.43	0.92	0.75	0.00	0.90	0.94	0.91	0.95
gamma-delta T cell	1776	0.33	0.08	0.77	0.54	0.00	0.55	0.67	0.47	0.80
fibroblast of cardiac tissue	1752	0.95	0.28	0.99	0.49	0.00	0.94	0.78	0.72	0.97
paneth cell of epithelium of small intestine	1662	0.51	0.40	0.79	0.63	0.00	0.70	0.68	0.71	0.82
club cell	1575	0.83	0.68	0.91	0.71	0.00	0.81	0.82	0.77	0.89
intestinal crypt stem cell of colon	1553	0.77	0.42	0.78	0.71	0.00	0.82	0.86	0.84	0.91
progenitor cell of mammary luminal epithelium	1525	0.98	0.00	0.99	0.97	0.00	0.88	0.95	0.87	0.99
epithelial cell	1512	0.91	0.22	0.97	0.78	0.00	0.91	0.93	0.91	0.96
basophil	1509	0.56	0.00	0.97	0.86	0.00	0.88	0.73	0.79	0.94
large intestine goblet cell	1425	0.89	0.14	0.93	0.68	0.00	0.89	0.94	0.89	0.95
eye photoreceptor cell	1394	0.92	0.91	0.97	0.96	0.00	0.95	0.99	0.98	0.98
epithelial cell of uterus	1274	0.95	0.23	0.98	0.62	0.00	0.94	0.95	0.87	0.98
enterocyte of epithelium proper of small intestine	1266	0.35	0.00	0.78	0.55	0.00	0.83	0.61	0.67	0.82
tissue-resident macrophage	1239	0.60	0.00	0.86	0.60	0.00	0.37	0.43	0.50	0.72
acinar cell	1225	0.86	0.21	0.97	0.87	0.00	0.89	0.90	0.89	0.94
non-classical monocyte	1162	0.23	0.29	0.54	0.37	0.00	0.35	0.40	0.37	0.55
lung ciliated cell	1090	0.75	0.28	0.98	0.93	0.00	0.96	0.94	0.94	0.97
activated CD8-positive, alpha-beta T cell	1044	0.22	0.00	0.85	0.56	0.00	0.55	0.36	0.29	0.72
alveolar adventitial fibroblast	1007	0.75	0.02	0.94	0.56	0.00	0.81	0.77	0.72	0.95
naive thymus-derived CD8-positive, alpha-beta T cell	944	0.13	0.00	0.60	0.31	0.00	0.26	0.15	0.14	0.53
adventitial cell	954	0.18	0.00	0.89	0.51	0.00	0.45	0.27	0.37	0.75
respiratory goblet cell	926	0.65	0.42	0.91	0.73	0.00	0.62	0.63	0.65	0.87
theca cell	920	0.63	0.00	0.87	0.84	0.00	0.62	0.72	0.57	0.89
myeloid leukocyte	906	0.18	0.00	0.85	0.40	0.00	0.67	0.24	0.25	0.80
keratocyte	887	0.14	0.00	0.78	0.24	0.00	0.49	0.49	0.39	0.78
enteroglial cell	885	0.83	0.61	0.97	0.92	0.00	0.93	0.93	0.82	0.92
innate lymphoid cell	882	0.21	0.13	0.59	0.45	0.00	0.50	0.23	0.26	0.47
erythroid progenitor cell	877	0.57	0.54	0.82	0.80	0.00	0.77	0.76	0.72	0.79
myometrial cell	817	0.74	0.00	0.87	0.76	0.00	0.56	0.67	0.59	0.83
endothelial cell of vascular tree	790	0.46	0.01	0.81	0.51	0.00	0.70	0.57	0.47	0.80
hematopoietic stem cell	782	0.72	0.60	0.85	0.80	0.00	0.74	0.85	0.83	0.87
salivary gland cell	773	0.53	0.00	0.93	0.73	0.00	0.86	0.68	0.64	0.91
granulocyte	685	0.22	0.00	0.71	0.62	0.00	0.49	0.29	0.20	0.77
CD8-positive, alpha-beta thymocyte	649	0.23	0.00	0.60	0.38	0.00	0.37	0.33	0.31	0.72
ciliated columnar cell of tracheobronchial tree	632	0.38	0.04	0.97	0.87	0.00	0.83	0.93	0.91	0.98
intrahepatic cholangiocyte	592	0.96	0.03	0.98	0.84	0.00	0.96	0.98	0.91	0.99
mural cell	560	0.26	0.06	0.97	0.68	0.00	0.67	0.68	0.48	0.96
intestinal crypt stem cell of small intestine	526	0.12	0.09	0.45	0.35	0.00	0.37	0.50	0.57	0.65
activated CD4-positive, alpha-beta T cell	521	0.04	0.00	0.54	0.32	0.00	0.30	0.13	0.13	0.28
myeloid dendritic cell	502	0.14	0.06	0.56	0.38	0.00	0.21	0.17	0.20	0.33
Mueller cell	461	0.67	0.42	0.85	0.82	0.00	0.73	0.94	0.93	0.92
fast muscle cell	450	0.62	0.56	0.94	0.86	0.00	0.87	0.81	0.85	0.93
platelet	440	0.91	0.88	0.95	0.94	0.00	0.75	0.95	0.81	0.95
myoepithelial cell	437	0.49	0.18	0.92	0.75	0.00	0.62	0.64	0.44	0.87
common myeloid progenitor	408	0.43	0.34	0.82	0.75	0.00	0.78	0.74	0.81	0.87
thymocyte	413	0.00	0.00	0.68	0.47	0.00	0.28	0.21	0.33	0.89
intestinal tuft cell	395	0.83	0.77	0.97	0.86	0.00	0.92	0.97	0.97	0.96
pancreatic stellate cell	392	0.00	0.00	0.97	0.61	0.00	0.67	0.74	0.44	0.94
tendon cell	377	0.16	0.01	0.73	0.48	0.00	0.54	0.53	0.33	0.76
microglial cell	366	0.10	0.00	0.75	0.24	0.00	0.18	0.31	0.18	0.49
muscle cell	367	0.71	0.01	0.98	0.95	0.00	0.76	0.81	0.94	0.96
enterocyte of epithelium proper of jejunum	372	0.00	0.00	0.58	0.54	0.00	0.85	0.57	0.41	0.93
mesothelial cell	309	0.62	0.45	0.93	0.88	0.00	0.68	0.75	0.70	0.78
colon endothelial cell	315	0.00	0.00	0.87	0.38	0.00	0.80	0.38	0.35	0.91
colon macrophage	299	0.19	0.00	0.85	0.44	0.00	0.53	0.40	0.24	0.88
serous cell of epithelium of trachea	293	0.40	0.00	0.87	0.66	0.00	0.47	0.48	0.54	0.79
ciliated epithelial cell	291	0.87	0.00	0.97	0.81	0.00	0.94	0.98	0.92	0.99
Schwann cell	290	0.64	0.42	0.87	0.80	0.00	0.69	0.89	0.74	0.89
mucus secreting cell	233	0.56	0.02	0.89	0.73	0.00	0.68	0.67	0.74	0.86
supporting cell of vestibular epithelium	243	0.84	0.00	0.70	0.77	0.00	0.71	1.00	0.86	0.99
enteroendocrine cell of small intestine	237	0.69	0.07	0.88	0.73	0.00	0.79	0.96	0.89	0.94
ovarian surface epithelial cell	217	0.45	0.06	0.93	0.88	0.00	0.68	0.88	0.71	0.95
transit amplifying cell of colon	204	0.56	0.24	0.62	0.50	0.00	0.43	0.69	0.57	0.85
glandular epithelial cell	212	0.56	0.02	0.90	0.70	0.00	0.74	0.87	0.71	0.98
melanocyte	208	0.54	0.23	0.86	0.64	0.00	0.75	0.79	0.65	0.91
tracheal goblet cell	213	0.61	0.15	0.88	0.67	0.00	0.66	0.83	0.67	0.95
hepatic stellate cell	194	0.51	0.00	0.82	0.44	0.00	0.62	0.60	0.44	0.84
bronchial smooth muscle cell	193	0.08	0.01	0.76	0.46	0.00	0.57	0.49	0.46	0.78
paneth cell of colon	186	0.00	0.05	0.76	0.70	0.00	0.37	0.75	0.37	0.91
tongue muscle cell	178	0.45	0.00	0.89	0.70	0.00	0.35	0.85	0.53	0.92
leukocyte	190	0.11	0.03	0.64	0.09	0.00	0.46	0.28	0.18	0.47
tuft cell of colon	155	0.00	0.02	0.88	0.61	0.00	0.81	0.93	0.91	0.96
slow muscle cell	165	0.00	0.06	0.88	0.72	0.00	0.75	0.95	0.91	0.95
ionocyte	144	0.62	0.08	0.82	0.74	0.00	0.76	0.85	0.73	0.92
connective tissue cell	133	0.00	0.00	0.96	0.90	0.00	0.25	0.51	0.25	0.93
sebum secreting cell	119	0.00	0.01	0.91	0.53	0.00	0.88	0.90	0.66	0.93
neuro-medullary thymic epithelial cell	121	0.30	0.24	0.85	0.71	0.00	0.39	0.45	0.58	0.50
endothelial cell of arteriole	114	0.00	0.00	0.93	0.30	0.00	0.57	0.75	0.43	0.98
male germ cell	103	0.80	0.00	0.92	0.88	0.00	0.85	1.00	0.80	0.99
type B pancreatic cell	87	0.66	0.00	0.93	0.86	0.00	0.82	1.00	0.94	0.99
hematopoietic cell	92	0.00	0.00	0.76	0.69	0.00	0.14	0.64	0.49	0.85
plasmacytoid dendritic cell	91	0.52	0.30	0.76	0.63	0.00	0.09	0.58	0.32	0.72
neuron	76	0.00	0.00	0.98	0.81	0.00	0.57	0.67	0.74	0.96
myeloid cell	72	0.00	0.00	0.62	0.00	0.00	0.36	0.38	0.24	0.87
myo-medullary thymic epithelial cell	70	0.65	0.00	0.95	0.79	0.00	0.65	0.77	0.92	0.93
Langerhans cell	68	0.35	0.03	0.84	0.58	0.00	0.10	0.32	0.35	0.54
interstitial cell of Cajal	63	0.00	0.00	0.95	0.54	0.00	0.37	0.56	0.51	0.94
peritubular myoid cell	61	0.24	0.00	0.71	0.51	0.00	0.45	0.69	0.58	0.76
retinal pigment epithelial cell	62	0.00	0.00	0.94	0.89	0.00	0.76	1.00	0.95	0.98
spermatogonium	52	0.00	0.00	0.75	0.65	0.00	0.39	0.90	0.75	0.88
retinal bipolar neuron	55	0.00	0.03	0.85	0.70	0.00	0.65	0.85	0.95	0.89
endothelial cell of venule	49	0.00	0.00	0.95	0.19	0.00	0.46	0.96	0.50	0.98
vestibular dark cell	42	0.00	0.00	0.41	0.24	0.00	0.48	1.00	0.90	0.95
pancreatic A cell	46	0.00	0.00	0.95	0.85	0.00	0.62	1.00	0.99	1.00
type L enteroendocrine cell	38	0.00	0.00	0.85	0.63	0.00	0.27	0.99	0.94	0.97
medullary thymic epithelial cell	40	0.00	0.00	0.81	0.48	0.00	0.66	0.99	0.74	0.87
adipocyte	37	0.00	0.00	0.67	0.55	0.00	0.41	0.69	0.60	0.86
transit amplifying cell of small intestine	33	0.00	0.00	0.52	0.34	0.00	0.30	0.79	0.70	0.90
taste receptor cell	28	0.00	0.00	0.86	0.48	0.00	0.16	0.88	0.36	0.93
enterochromaffin-like cell	24	0.00	0.03	0.81	0.44	0.00	0.79	0.96	0.91	0.96
enteroendocrine cell	23	0.00	0.00	0.91	0.51	0.00	0.48	0.94	0.94	0.96
pulmonary ionocyte	25	0.00	0.00	0.78	0.38	0.00	0.70	1.00	0.86	0.96
glial cell	19	0.00	0.00	0.73	0.58	0.00	0.26	0.43	0.38	0.78
oocyte	17	0.00	0.00	0.91	0.76	0.00	0.26	0.92	0.94	0.92
serous cell of epithelium of bronchus	13	0.00	0.00	0.82	0.38	0.00	0.24	0.74	0.96	0.92
radial glial cell	11	0.00	0.00	0.00	0.00	0.00	0.05	0.31	0.30	0.48
Leydig cell	7	0.00	0.00	0.00	0.18	0.00	0.34	0.35	0.88	0.93
pancreatic D cell	9	0.00	0.00	0.71	0.53	0.00	0.95	1.00	0.90	1.00
T follicular helper cell	6	0.00	0.00	0.29	0.00	0.00	0.03	0.55	0.43	0.77
retina horizontal cell	3	0.00	0.00	0.00	0.00	0.00	0.21	1.00	1.00	0.50
pancreatic PP cell	2	0.00	0.00	0.00	0.00	0.00	0.10	1.00	1.00	1.00
epithelial fate stem cell	2	0.00	0.00	0.00	0.00	0.00	0.17	1.00	1.00	0.67
mesenchymal cell	2	0.00	0.00	0.00	0.00	0.00	0.01	0.09	0.67	0.00
erythroid lineage cell	2	0.00	0.00	0.00	0.00	0.00	0.03	1.00	0.36	0.00
retinal ganglion cell	1	0.00	0.00	0.00	0.00	0.00	0.06	0.08	0.33	0.67

References

Tabula Sapiens reveals transcription factor expression, senescence effects, and sex-specific features in cell types from 28 human organs and tissues, The Tabula Sapiens Consortium; bioRxiv, doi: https://doi.org/10.1101/2024.12.03.626516