targetId
stringlengths
15
15
diseaseId
stringlengths
9
15
nctid
stringlengths
11
11
clinicalStatus
stringclasses
9 values
clinicalPhase
int64
0
4
studyStartDate
stringlengths
10
10
stopStatus
stringclasses
3 values
isStopped
stringclasses
1 value
phase4
stringclasses
1 value
phase3
stringclasses
1 value
phase2
stringclasses
1 value
id
int64
0
1,709B
why_stopped
stringlengths
2
254
phase
stringclasses
7 values
start_date
stringlengths
10
10
status
stringclasses
3 values
last_update_posted_date
stringlengths
10
10
completion_date
stringlengths
10
10
prediction
stringclasses
15 values
metaprediction
stringclasses
6 values
max_l2g
float64
0.05
0.9
l2g_075
stringclasses
1 value
l2g_05
stringclasses
1 value
l2g_025
stringclasses
1 value
l2g_01
stringclasses
1 value
l2g_005
stringclasses
1 value
taId
stringclasses
23 values
taLabel
stringclasses
24 values
taLabelSimple
stringclasses
2 values
gc
float64
0
5
lof_tolerance
stringclasses
2 values
rnaDistribution
stringclasses
5 values
rnaSpecificity
stringclasses
5 values
partnersBin
stringclasses
4 values
datasourceId
stringclasses
22 values
datatypeId
stringclasses
7 values
total
int64
413k
413k
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT03057145
Completed
1
2017-03-10
null
null
null
null
null
1,632,087,572,597
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02986100
Completed
1
2016-11-01
null
null
null
null
null
1,666,447,312,036
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
4
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
europepmc
literature
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
chembl
known_drug
413,311
ENSG00000041880
EFO_0000616
NCT02430311
Completed
1
2015-06-10
null
null
null
null
null
1,683,627,181,577
null
null
null
null
null
null
null
null
null
null
null
null
null
null
MONDO_0045024
cell proliferation disorder
Oncology
null
LoF tolerant
Detected in all
Low tissue specificity
from1to10
expression_atlas
rna_expression
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01104558
Completed
4
2008-12-01
null
null
Phase IV
Phase III+
Phase II+
206,158,431,447
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00589303
Terminated
3
2007-12-01
Terminated
stopped
null
Phase III+
Phase II+
438,086,664,669
Lack of funding
Phase 3
31/12/2007
Terminated
04/04/2013
31/07/2011
Business_Administrative
Business_Administrative
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT02717507
Active, not recruiting
2
2016-04-04
null
null
null
null
Phase II+
755,914,245,639
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
null
null
4
null
null
null
Phase IV
Phase III+
Phase II+
1,408,749,273,126
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00402376
Terminated
4
2007-04-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
1,460,288,881,111
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00937092
Unknown status
4
2009-01-01
null
null
Phase IV
Phase III+
Phase II+
1,460,288,881,785
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT03421860
Completed
4
2017-02-23
null
null
Phase IV
Phase III+
Phase II+
197,568,495,664
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01178528
Completed
3
2009-09-01
null
null
null
Phase III+
Phase II+
214,748,366,854
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01042873
Unknown status
4
2010-01-01
null
null
Phase IV
Phase III+
Phase II+
257,698,038,465
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01868880
Withdrawn
4
2016-02-01
Withdrawn
stopped
Phase IV
Phase III+
Phase II+
257,698,038,658
difficulties in recruiting patients
Phase 4
29/02/2016
Withdrawn
13/03/2020
31/12/2023
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01060293
Terminated
4
2009-07-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
283,467,843,639
Safety issues in the LDFD-group (higher heart rate with dopamine)
Phase 4
31/07/2009
Terminated
11/09/2013
31/12/2013
Safety_Sideeffects
Safety_Sideeffects
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT01140399
Terminated
4
2011-02-01
Terminated
stopped
Phase IV
Phase III+
Phase II+
317,827,580,474
insufficient enrollment
Phase 4
28/02/2011
Terminated
10/04/2017
30/04/2017
Insufficient_Enrollment
Neutral
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00953303
Completed
2
2009-01-01
null
null
null
null
Phase II+
335,007,450,137
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00953303
Completed
2
2009-01-01
null
null
null
null
Phase II+
335,007,450,137
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
4
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311
ENSG00000043591
EFO_0003144
NCT00953303
Completed
2
2009-01-01
null
null
null
null
Phase II+
335,007,450,137
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
chembl
known_drug
413,311
ENSG00000043591
EFO_0003144
NCT00953303
Completed
2
2009-01-01
null
null
null
null
Phase II+
335,007,450,137
null
null
null
null
null
null
null
null
null
null
null
null
null
null
EFO_0000319
cardiovascular disease
Other
null
LoF tolerant
Detected in many
Tissue enhanced
from1to10
europepmc
literature
413,311