Dataset Preview
Full Screen
The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed
Error code:   DatasetGenerationError
Exception:    TypeError
Message:      Couldn't cast array of type
struct<a: list<item: int64>, b: list<item: int64>, c: list<item: int64>, d: list<item: int64>, e: list<item: int64>, f: list<item: int64>, g: list<item: int64>, h: list<item: int64>, i: list<item: int64>, j: list<item: int64>, k: list<item: int64>, l: list<item: int64>>
to
{'a': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'b': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'c': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'd': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'e': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'f': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'g': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'h': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'i': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'j': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'k': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'l': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'm': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'n': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'o': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'p': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None)}
Traceback:    Traceback (most recent call last):
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 2011, in _prepare_split_single
                  writer.write_table(table)
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/arrow_writer.py", line 585, in write_table
                  pa_table = table_cast(pa_table, self._schema)
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2302, in table_cast
                  return cast_table_to_schema(table, schema)
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2261, in cast_table_to_schema
                  arrays = [cast_array_to_feature(table[name], feature) for name, feature in features.items()]
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2261, in <listcomp>
                  arrays = [cast_array_to_feature(table[name], feature) for name, feature in features.items()]
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1802, in wrapper
                  return pa.chunked_array([func(chunk, *args, **kwargs) for chunk in array.chunks])
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 1802, in <listcomp>
                  return pa.chunked_array([func(chunk, *args, **kwargs) for chunk in array.chunks])
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2122, in cast_array_to_feature
                  raise TypeError(f"Couldn't cast array of type\n{_short_str(array.type)}\nto\n{_short_str(feature)}")
              TypeError: Couldn't cast array of type
              struct<a: list<item: int64>, b: list<item: int64>, c: list<item: int64>, d: list<item: int64>, e: list<item: int64>, f: list<item: int64>, g: list<item: int64>, h: list<item: int64>, i: list<item: int64>, j: list<item: int64>, k: list<item: int64>, l: list<item: int64>>
              to
              {'a': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'b': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'c': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'd': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'e': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'f': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'g': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'h': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'i': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'j': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'k': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'l': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'm': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'n': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'o': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None), 'p': Sequence(feature=Value(dtype='int64', id=None), length=-1, id=None)}
              
              The above exception was the direct cause of the following exception:
              
              Traceback (most recent call last):
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1529, in compute_config_parquet_and_info_response
                  parquet_operations = convert_to_parquet(builder)
                File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1154, in convert_to_parquet
                  builder.download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1027, in download_and_prepare
                  self._download_and_prepare(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1122, in _download_and_prepare
                  self._prepare_split(split_generator, **prepare_split_kwargs)
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1882, in _prepare_split
                  for job_id, done, content in self._prepare_split_single(
                File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 2038, in _prepare_split_single
                  raise DatasetGenerationError("An error occurred while generating the dataset") from e
              datasets.exceptions.DatasetGenerationError: An error occurred while generating the dataset

Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.

pdf_hash
string
fig_key
string
fig_uri
string
text
string
width
int64
height
int64
subcaptions
dict
subfigures
list
tokens
list
81c7347b2d837f84ec3751aeb747fe3a38612c97
Figure1
4-Figure1-1.png
Fig. 1. An illustrative case. A-D: Initial MRI findings. E-H: Follow-up imaging after 7 months without surgical intervention.
1,340
1,352
{ "a": [ 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 ], "b": null, "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "66e14d81-173c-41c6-b0f8-72f0078bd180", "label": "a", "points": [ [ 3.2, 0 ], [ 3.2, 438.2 ], [ 439.3, 438.2 ], [ 439.3, 0 ] ], "color": "yellow" }, { "id": "3ba2e742-e6dc-4bb6-a29e-01dc3b62371f", "label": "a", "points": [ [ 452, 2.1 ], [ 452, 438.2 ], [ 892.3, 438.2 ], [ 892.3, 2.1 ] ], "color": "cyan" }, { "id": "13dd0017-a846-4f23-9c34-20bc1ffb6b43", "label": "a", "points": [ [ 902.9, 2.1 ], [ 902.9, 442.4 ], [ 1334.7, 442.4 ], [ 1334.7, 2.1 ] ], "color": "magenta" }, { "id": "96fa41ab-f227-42eb-b1f1-4a701de4f3b9", "label": "a", "points": [ [ 3.2, 448.8 ], [ 3.2, 887 ], [ 439.3, 887 ], [ 439.3, 448.8 ] ], "color": "springgreen" }, { "id": "31f39289-84ff-488a-ac25-cc8948a53b0e", "label": "e", "points": [ [ 454.1, 442.4 ], [ 454.1, 891.2 ], [ 888.1, 891.2 ], [ 888.1, 442.4 ] ], "color": "tomato" }, { "id": "d5759fa7-6047-4a5e-9b88-5542249bfbea", "label": "e", "points": [ [ 902.9, 450.9 ], [ 902.9, 889.1 ], [ 1336.9, 889.1 ], [ 1336.9, 450.9 ] ], "color": "deepskyblue" }, { "id": "adcc210c-8ab9-4bf1-9fef-8f00882362e9", "label": "e", "points": [ [ 5.3, 895.5 ], [ 5.3, 1344.3 ], [ 441.4, 1344.3 ], [ 441.4, 895.5 ] ], "color": "orange" }, { "id": "38010823-258c-4a7f-b5b0-ed185cb5efdc", "label": "e", "points": [ [ 449.9, 899.7 ], [ 449.9, 1337.9 ], [ 890.2, 1337.9 ], [ 890.2, 899.7 ] ], "color": "hotpink" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "1", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "An", "start": 8, "end": 10, "id": 4 }, { "text": "illustrative", "start": 11, "end": 23, "id": 5 }, { "text": "case", "start": 24, "end": 28, "id": 6 }, { "text": ".", "start": 28, "end": 29, "id": 7 }, { "text": "A", "start": 30, "end": 31, "id": 8 }, { "text": "-", "start": 31, "end": 32, "id": 9 }, { "text": "D", "start": 32, "end": 33, "id": 10 }, { "text": ":", "start": 33, "end": 34, "id": 11 }, { "text": "Initial", "start": 35, "end": 42, "id": 12 }, { "text": "MRI", "start": 43, "end": 46, "id": 13 }, { "text": "findings", "start": 47, "end": 55, "id": 14 }, { "text": ".", "start": 55, "end": 56, "id": 15 }, { "text": "E", "start": 57, "end": 58, "id": 16 }, { "text": "-", "start": 58, "end": 59, "id": 17 }, { "text": "H", "start": 59, "end": 60, "id": 18 }, { "text": ":", "start": 60, "end": 61, "id": 19 }, { "text": "Follow", "start": 62, "end": 68, "id": 20 }, { "text": "-", "start": 68, "end": 69, "id": 21 }, { "text": "up", "start": 69, "end": 71, "id": 22 }, { "text": "imaging", "start": 72, "end": 79, "id": 23 }, { "text": "after", "start": 80, "end": 85, "id": 24 }, { "text": "7", "start": 86, "end": 87, "id": 25 }, { "text": "months", "start": 88, "end": 94, "id": 26 }, { "text": "without", "start": 95, "end": 102, "id": 27 }, { "text": "surgical", "start": 103, "end": 111, "id": 28 }, { "text": "intervention", "start": 112, "end": 124, "id": 29 }, { "text": ".", "start": 124, "end": 125, "id": 30 } ]
6ff2ceb4d5c5da0d48d50ba3dcb011dc69dc7818
Figure1
2-Figure1-1.png
Figure 1 Radiologic imaging tests. (A) Enhanced CT showed diffuse enlargement of the thyroid gland and a tumor (arrows) in the right lobe of the thyroid. (B) Thyroidal uptake of radioiodine showed diffuse enlargement of both lobes of the thyroid with homogeneously increased uptake (52.74%).
614
1,246
{ "a": [ 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31 ], "b": [ 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "d99537a5-82d3-49d0-b46b-90e52e756134", "label": "a", "points": [ [ 2, 4.8 ], [ 2, 590.9 ], [ 611, 590.9 ], [ 611, 4.8 ] ], "color": "yellow" }, { "id": "16b2c11e-e7b1-4c13-b698-6f830ff8bcc9", "label": "b", "points": [ [ 13, 654.9 ], [ 13, 1244.9 ], [ 598, 1244.9 ], [ 598, 654.9 ] ], "color": "cyan" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": "Radiologic", "start": 9, "end": 19, "id": 2 }, { "text": "imaging", "start": 20, "end": 27, "id": 3 }, { "text": "tests", "start": 28, "end": 33, "id": 4 }, { "text": ".", "start": 33, "end": 34, "id": 5 }, { "text": "(", "start": 35, "end": 36, "id": 6 }, { "text": "A", "start": 36, "end": 37, "id": 7 }, { "text": ")", "start": 37, "end": 38, "id": 8 }, { "text": "Enhanced", "start": 39, "end": 47, "id": 9 }, { "text": "CT", "start": 48, "end": 50, "id": 10 }, { "text": "showed", "start": 51, "end": 57, "id": 11 }, { "text": "diffuse", "start": 58, "end": 65, "id": 12 }, { "text": "enlargement", "start": 66, "end": 77, "id": 13 }, { "text": "of", "start": 78, "end": 80, "id": 14 }, { "text": "the", "start": 81, "end": 84, "id": 15 }, { "text": "thyroid", "start": 85, "end": 92, "id": 16 }, { "text": "gland", "start": 93, "end": 98, "id": 17 }, { "text": "and", "start": 99, "end": 102, "id": 18 }, { "text": "a", "start": 103, "end": 104, "id": 19 }, { "text": "tumor", "start": 105, "end": 110, "id": 20 }, { "text": "(", "start": 111, "end": 112, "id": 21 }, { "text": "arrows", "start": 112, "end": 118, "id": 22 }, { "text": ")", "start": 118, "end": 119, "id": 23 }, { "text": "in", "start": 120, "end": 122, "id": 24 }, { "text": "the", "start": 123, "end": 126, "id": 25 }, { "text": "right", "start": 127, "end": 132, "id": 26 }, { "text": "lobe", "start": 133, "end": 137, "id": 27 }, { "text": "of", "start": 138, "end": 140, "id": 28 }, { "text": "the", "start": 141, "end": 144, "id": 29 }, { "text": "thyroid", "start": 145, "end": 152, "id": 30 }, { "text": ".", "start": 152, "end": 153, "id": 31 }, { "text": "(", "start": 154, "end": 155, "id": 32 }, { "text": "B", "start": 155, "end": 156, "id": 33 }, { "text": ")", "start": 156, "end": 157, "id": 34 }, { "text": "Thyroidal", "start": 158, "end": 167, "id": 35 }, { "text": "uptake", "start": 168, "end": 174, "id": 36 }, { "text": "of", "start": 175, "end": 177, "id": 37 }, { "text": "radioiodine", "start": 178, "end": 189, "id": 38 }, { "text": "showed", "start": 190, "end": 196, "id": 39 }, { "text": "diffuse", "start": 197, "end": 204, "id": 40 }, { "text": "enlargement", "start": 205, "end": 216, "id": 41 }, { "text": "of", "start": 217, "end": 219, "id": 42 }, { "text": "both", "start": 220, "end": 224, "id": 43 }, { "text": "lobes", "start": 225, "end": 230, "id": 44 }, { "text": "of", "start": 231, "end": 233, "id": 45 }, { "text": "the", "start": 234, "end": 237, "id": 46 }, { "text": "thyroid", "start": 238, "end": 245, "id": 47 }, { "text": "with", "start": 246, "end": 250, "id": 48 }, { "text": "homogeneously", "start": 251, "end": 264, "id": 49 }, { "text": "increased", "start": 265, "end": 274, "id": 50 }, { "text": "uptake", "start": 275, "end": 281, "id": 51 }, { "text": "(", "start": 282, "end": 283, "id": 52 }, { "text": "52.74", "start": 283, "end": 288, "id": 53 }, { "text": "%", "start": 288, "end": 289, "id": 54 }, { "text": ")", "start": 289, "end": 290, "id": 55 }, { "text": ".", "start": 290, "end": 291, "id": 56 } ]
968742d6d4211d039e742f76cf39b69f06009f4b
Figure3
6-Figure3-1.png
Figure 3. Effects of LIPUS treatment on brain edema in TBI mice. (a) Representative T2-weighted MRI images at 1 and 4 days post-TBI. The damaged area is defined as a hyperintense region over the right parietal cortex, indicating edema formation. Dotted line shows location of regions of interest. (b) Quantification revealed significantly smaller edema volumes in LIPUS-treated mice compared with non-treated mice at 1 and 4 days. # Denotes significantly different from non-treated TBI group ( ### p < 0.001, n = 6).
896
522
{ "a": [ 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57 ], "b": [ 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "b9645074-1e67-46d5-9575-84eb3deee57f", "label": "a", "points": [ [ 10.6, 2.8 ], [ 10.6, 484.1 ], [ 555.6, 484.1 ], [ 555.6, 2.8 ] ], "color": "yellow" }, { "id": "07543e2d-6adb-4bde-9a4c-d3573133709c", "label": "b", "points": [ [ 558.4, 5.7 ], [ 558.4, 475.6 ], [ 893.9, 475.6 ], [ 893.9, 5.7 ] ], "color": "cyan" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "3", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Effects", "start": 10, "end": 17, "id": 3 }, { "text": "of", "start": 18, "end": 20, "id": 4 }, { "text": "LIPUS", "start": 21, "end": 26, "id": 5 }, { "text": "treatment", "start": 27, "end": 36, "id": 6 }, { "text": "on", "start": 37, "end": 39, "id": 7 }, { "text": "brain", "start": 40, "end": 45, "id": 8 }, { "text": "edema", "start": 46, "end": 51, "id": 9 }, { "text": "in", "start": 52, "end": 54, "id": 10 }, { "text": "TBI", "start": 55, "end": 58, "id": 11 }, { "text": "mice", "start": 59, "end": 63, "id": 12 }, { "text": ".", "start": 63, "end": 64, "id": 13 }, { "text": "(", "start": 65, "end": 66, "id": 14 }, { "text": "a", "start": 66, "end": 67, "id": 15 }, { "text": ")", "start": 67, "end": 68, "id": 16 }, { "text": "Representative", "start": 69, "end": 83, "id": 17 }, { "text": "T2-weighted", "start": 84, "end": 95, "id": 18 }, { "text": "MRI", "start": 96, "end": 99, "id": 19 }, { "text": "images", "start": 100, "end": 106, "id": 20 }, { "text": "at", "start": 107, "end": 109, "id": 21 }, { "text": "1", "start": 110, "end": 111, "id": 22 }, { "text": "and", "start": 112, "end": 115, "id": 23 }, { "text": "4", "start": 116, "end": 117, "id": 24 }, { "text": "days", "start": 118, "end": 122, "id": 25 }, { "text": "post", "start": 123, "end": 127, "id": 26 }, { "text": "-", "start": 127, "end": 128, "id": 27 }, { "text": "TBI", "start": 128, "end": 131, "id": 28 }, { "text": ".", "start": 131, "end": 132, "id": 29 }, { "text": "The", "start": 133, "end": 136, "id": 30 }, { "text": "damaged", "start": 137, "end": 144, "id": 31 }, { "text": "area", "start": 145, "end": 149, "id": 32 }, { "text": "is", "start": 150, "end": 152, "id": 33 }, { "text": "defined", "start": 153, "end": 160, "id": 34 }, { "text": "as", "start": 161, "end": 163, "id": 35 }, { "text": "a", "start": 164, "end": 165, "id": 36 }, { "text": "hyperintense", "start": 166, "end": 178, "id": 37 }, { "text": "region", "start": 179, "end": 185, "id": 38 }, { "text": "over", "start": 186, "end": 190, "id": 39 }, { "text": "the", "start": 191, "end": 194, "id": 40 }, { "text": "right", "start": 195, "end": 200, "id": 41 }, { "text": "parietal", "start": 201, "end": 209, "id": 42 }, { "text": "cortex", "start": 210, "end": 216, "id": 43 }, { "text": ",", "start": 216, "end": 217, "id": 44 }, { "text": "indicating", "start": 218, "end": 228, "id": 45 }, { "text": "edema", "start": 229, "end": 234, "id": 46 }, { "text": "formation", "start": 235, "end": 244, "id": 47 }, { "text": ".", "start": 244, "end": 245, "id": 48 }, { "text": "Dotted", "start": 246, "end": 252, "id": 49 }, { "text": "line", "start": 253, "end": 257, "id": 50 }, { "text": "shows", "start": 258, "end": 263, "id": 51 }, { "text": "location", "start": 264, "end": 272, "id": 52 }, { "text": "of", "start": 273, "end": 275, "id": 53 }, { "text": "regions", "start": 276, "end": 283, "id": 54 }, { "text": "of", "start": 284, "end": 286, "id": 55 }, { "text": "interest", "start": 287, "end": 295, "id": 56 }, { "text": ".", "start": 295, "end": 296, "id": 57 }, { "text": "(", "start": 297, "end": 298, "id": 58 }, { "text": "b", "start": 298, "end": 299, "id": 59 }, { "text": ")", "start": 299, "end": 300, "id": 60 }, { "text": "Quantification", "start": 301, "end": 315, "id": 61 }, { "text": "revealed", "start": 316, "end": 324, "id": 62 }, { "text": "significantly", "start": 325, "end": 338, "id": 63 }, { "text": "smaller", "start": 339, "end": 346, "id": 64 }, { "text": "edema", "start": 347, "end": 352, "id": 65 }, { "text": "volumes", "start": 353, "end": 360, "id": 66 }, { "text": "in", "start": 361, "end": 363, "id": 67 }, { "text": "LIPUS", "start": 364, "end": 369, "id": 68 }, { "text": "-", "start": 369, "end": 370, "id": 69 }, { "text": "treated", "start": 370, "end": 377, "id": 70 }, { "text": "mice", "start": 378, "end": 382, "id": 71 }, { "text": "compared", "start": 383, "end": 391, "id": 72 }, { "text": "with", "start": 392, "end": 396, "id": 73 }, { "text": "non", "start": 397, "end": 400, "id": 74 }, { "text": "-", "start": 400, "end": 401, "id": 75 }, { "text": "treated", "start": 401, "end": 408, "id": 76 }, { "text": "mice", "start": 409, "end": 413, "id": 77 }, { "text": "at", "start": 414, "end": 416, "id": 78 }, { "text": "1", "start": 417, "end": 418, "id": 79 }, { "text": "and", "start": 419, "end": 422, "id": 80 }, { "text": "4", "start": 423, "end": 424, "id": 81 }, { "text": "days", "start": 425, "end": 429, "id": 82 }, { "text": ".", "start": 429, "end": 430, "id": 83 }, { "text": "#", "start": 431, "end": 432, "id": 84 }, { "text": "Denotes", "start": 433, "end": 440, "id": 85 }, { "text": "significantly", "start": 441, "end": 454, "id": 86 }, { "text": "different", "start": 455, "end": 464, "id": 87 }, { "text": "from", "start": 465, "end": 469, "id": 88 }, { "text": "non", "start": 470, "end": 473, "id": 89 }, { "text": "-", "start": 473, "end": 474, "id": 90 }, { "text": "treated", "start": 474, "end": 481, "id": 91 }, { "text": "TBI", "start": 482, "end": 485, "id": 92 }, { "text": "group", "start": 486, "end": 491, "id": 93 }, { "text": "(", "start": 492, "end": 493, "id": 94 }, { "text": "#", "start": 494, "end": 495, "id": 95 }, { "text": "#", "start": 495, "end": 496, "id": 96 }, { "text": "#", "start": 496, "end": 497, "id": 97 }, { "text": "p", "start": 498, "end": 499, "id": 98 }, { "text": "<", "start": 500, "end": 501, "id": 99 }, { "text": "0.001", "start": 502, "end": 507, "id": 100 }, { "text": ",", "start": 507, "end": 508, "id": 101 }, { "text": "n", "start": 509, "end": 510, "id": 102 }, { "text": "=", "start": 511, "end": 512, "id": 103 }, { "text": "6", "start": 513, "end": 514, "id": 104 }, { "text": ")", "start": 514, "end": 515, "id": 105 }, { "text": ".", "start": 515, "end": 516, "id": 106 } ]
63c351a976c2c73ca05f7e94e5a0a682dfe17e46
Figure1
3-Figure1-1.png
Figure 1. The distribution of DNA, centrosomes, and microtubules in aphidicolin-injected embryos at various times after injection. Embryos were injected with aphidicolin at about the time of pole cell formation (nuclear cycle 9, see text). They were allowed to develop for various lengths of time before fixation and staining with Rb188 (anti-centrosome) and YIl/2 (anti-tubulin) followed by rhodamine-coupled goat anti-rabbit and fluorescein-coupled mouse anti-rat antibodies. The embryos were finally incubated with Hoeehst 33258 (see Materials and Methods). The figure shows fields from typical embryos fixed 10 (A), 45 (B), and 90 (C) min after injection of the drug. Bar, 20 ~m.
1,390
1,472
{ "a": [ 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118 ], "b": [ 130, 131, 132, 133, 134, 135, 136, 107, 108, 109, 110, 111, 112, 113, 114, 120, 121, 122, 123 ], "c": [ 128, 129, 130, 131, 132, 133, 134, 135, 136, 107, 108, 109, 110, 111, 112, 113, 114, 126, 127 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "456ef6b6-b3f5-4d80-b91c-74f663cf567a", "label": "a", "points": [ [ 14.4, -0.4 ], [ 14.4, 436.6 ], [ 453.5, 436.6 ], [ 453.5, -0.4 ] ], "color": "yellow" }, { "id": "d7f42883-f80c-42e6-b335-19b3d020ef9c", "label": "a", "points": [ [ 488.6, 1.8 ], [ 488.6, 434.4 ], [ 919, 434.4 ], [ 919, 1.8 ] ], "color": "cyan" }, { "id": "3544fb21-4be7-4e53-804d-23ae269ddc36", "label": "a", "points": [ [ 956.3, 4 ], [ 956.3, 438.8 ], [ 1386.7, 438.8 ], [ 1386.7, 4 ] ], "color": "magenta" }, { "id": "8774a95b-68a4-44dc-b57a-aba9c6cd7768", "label": "b", "points": [ [ 10, 465.1 ], [ 10, 915.3 ], [ 455.7, 915.3 ], [ 455.7, 465.1 ] ], "color": "springgreen" }, { "id": "1629c715-1f15-4642-8c67-2021ea04ffb9", "label": "b", "points": [ [ 488.6, 465.1 ], [ 488.6, 906.5 ], [ 921.2, 906.5 ], [ 921.2, 465.1 ] ], "color": "tomato" }, { "id": "fa35c353-55b2-465c-814e-c19b65205071", "label": "b", "points": [ [ 949.8, 473.9 ], [ 949.8, 913.1 ], [ 1388.9, 913.1 ], [ 1388.9, 473.9 ] ], "color": "deepskyblue" }, { "id": "af5b9119-05f8-4bf0-b3dd-676bfa168525", "label": "c", "points": [ [ 7.8, 942.7 ], [ 7.8, 1379.7 ], [ 453.5, 1379.7 ], [ 453.5, 942.7 ] ], "color": "orange" }, { "id": "d6b2413b-4cb3-4f00-812d-853b6c5a07a2", "label": "c", "points": [ [ 490.8, 942.7 ], [ 490.8, 1375.3 ], [ 919, 1375.3 ], [ 919, 942.7 ] ], "color": "hotpink" }, { "id": "acfb1df5-2395-441b-a907-e8086d346a12", "label": "c", "points": [ [ 947.6, 944.9 ], [ 947.6, 1375.3 ], [ 1382.3, 1375.3 ], [ 1382.3, 944.9 ] ], "color": "aquamarine" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "The", "start": 10, "end": 13, "id": 3 }, { "text": "distribution", "start": 14, "end": 26, "id": 4 }, { "text": "of", "start": 27, "end": 29, "id": 5 }, { "text": "DNA", "start": 30, "end": 33, "id": 6 }, { "text": ",", "start": 33, "end": 34, "id": 7 }, { "text": "centrosomes", "start": 35, "end": 46, "id": 8 }, { "text": ",", "start": 46, "end": 47, "id": 9 }, { "text": "and", "start": 48, "end": 51, "id": 10 }, { "text": "microtubules", "start": 52, "end": 64, "id": 11 }, { "text": "in", "start": 65, "end": 67, "id": 12 }, { "text": "aphidicolin", "start": 68, "end": 79, "id": 13 }, { "text": "-", "start": 79, "end": 80, "id": 14 }, { "text": "injected", "start": 80, "end": 88, "id": 15 }, { "text": "embryos", "start": 89, "end": 96, "id": 16 }, { "text": "at", "start": 97, "end": 99, "id": 17 }, { "text": "various", "start": 100, "end": 107, "id": 18 }, { "text": "times", "start": 108, "end": 113, "id": 19 }, { "text": "after", "start": 114, "end": 119, "id": 20 }, { "text": "injection", "start": 120, "end": 129, "id": 21 }, { "text": ".", "start": 129, "end": 130, "id": 22 }, { "text": "Embryos", "start": 131, "end": 138, "id": 23 }, { "text": "were", "start": 139, "end": 143, "id": 24 }, { "text": "injected", "start": 144, "end": 152, "id": 25 }, { "text": "with", "start": 153, "end": 157, "id": 26 }, { "text": "aphidicolin", "start": 158, "end": 169, "id": 27 }, { "text": "at", "start": 170, "end": 172, "id": 28 }, { "text": "about", "start": 173, "end": 178, "id": 29 }, { "text": "the", "start": 179, "end": 182, "id": 30 }, { "text": "time", "start": 183, "end": 187, "id": 31 }, { "text": "of", "start": 188, "end": 190, "id": 32 }, { "text": "pole", "start": 191, "end": 195, "id": 33 }, { "text": "cell", "start": 196, "end": 200, "id": 34 }, { "text": "formation", "start": 201, "end": 210, "id": 35 }, { "text": "(", "start": 211, "end": 212, "id": 36 }, { "text": "nuclear", "start": 212, "end": 219, "id": 37 }, { "text": "cycle", "start": 220, "end": 225, "id": 38 }, { "text": "9", "start": 226, "end": 227, "id": 39 }, { "text": ",", "start": 227, "end": 228, "id": 40 }, { "text": "see", "start": 229, "end": 232, "id": 41 }, { "text": "text", "start": 233, "end": 237, "id": 42 }, { "text": ")", "start": 237, "end": 238, "id": 43 }, { "text": ".", "start": 238, "end": 239, "id": 44 }, { "text": "They", "start": 240, "end": 244, "id": 45 }, { "text": "were", "start": 245, "end": 249, "id": 46 }, { "text": "allowed", "start": 250, "end": 257, "id": 47 }, { "text": "to", "start": 258, "end": 260, "id": 48 }, { "text": "develop", "start": 261, "end": 268, "id": 49 }, { "text": "for", "start": 269, "end": 272, "id": 50 }, { "text": "various", "start": 273, "end": 280, "id": 51 }, { "text": "lengths", "start": 281, "end": 288, "id": 52 }, { "text": "of", "start": 289, "end": 291, "id": 53 }, { "text": "time", "start": 292, "end": 296, "id": 54 }, { "text": "before", "start": 297, "end": 303, "id": 55 }, { "text": "fixation", "start": 304, "end": 312, "id": 56 }, { "text": "and", "start": 313, "end": 316, "id": 57 }, { "text": "staining", "start": 317, "end": 325, "id": 58 }, { "text": "with", "start": 326, "end": 330, "id": 59 }, { "text": "Rb188", "start": 331, "end": 336, "id": 60 }, { "text": "(", "start": 337, "end": 338, "id": 61 }, { "text": "anti", "start": 338, "end": 342, "id": 62 }, { "text": "-", "start": 342, "end": 343, "id": 63 }, { "text": "centrosome", "start": 343, "end": 353, "id": 64 }, { "text": ")", "start": 353, "end": 354, "id": 65 }, { "text": "and", "start": 355, "end": 358, "id": 66 }, { "text": "YIl/2", "start": 359, "end": 364, "id": 67 }, { "text": "(", "start": 365, "end": 366, "id": 68 }, { "text": "anti", "start": 366, "end": 370, "id": 69 }, { "text": "-", "start": 370, "end": 371, "id": 70 }, { "text": "tubulin", "start": 371, "end": 378, "id": 71 }, { "text": ")", "start": 378, "end": 379, "id": 72 }, { "text": "followed", "start": 380, "end": 388, "id": 73 }, { "text": "by", "start": 389, "end": 391, "id": 74 }, { "text": "rhodamine", "start": 392, "end": 401, "id": 75 }, { "text": "-", "start": 401, "end": 402, "id": 76 }, { "text": "coupled", "start": 402, "end": 409, "id": 77 }, { "text": "goat", "start": 410, "end": 414, "id": 78 }, { "text": "anti", "start": 415, "end": 419, "id": 79 }, { "text": "-", "start": 419, "end": 420, "id": 80 }, { "text": "rabbit", "start": 420, "end": 426, "id": 81 }, { "text": "and", "start": 427, "end": 430, "id": 82 }, { "text": "fluorescein", "start": 431, "end": 442, "id": 83 }, { "text": "-", "start": 442, "end": 443, "id": 84 }, { "text": "coupled", "start": 443, "end": 450, "id": 85 }, { "text": "mouse", "start": 451, "end": 456, "id": 86 }, { "text": "anti", "start": 457, "end": 461, "id": 87 }, { "text": "-", "start": 461, "end": 462, "id": 88 }, { "text": "rat", "start": 462, "end": 465, "id": 89 }, { "text": "antibodies", "start": 466, "end": 476, "id": 90 }, { "text": ".", "start": 476, "end": 477, "id": 91 }, { "text": "The", "start": 478, "end": 481, "id": 92 }, { "text": "embryos", "start": 482, "end": 489, "id": 93 }, { "text": "were", "start": 490, "end": 494, "id": 94 }, { "text": "finally", "start": 495, "end": 502, "id": 95 }, { "text": "incubated", "start": 503, "end": 512, "id": 96 }, { "text": "with", "start": 513, "end": 517, "id": 97 }, { "text": "Hoeehst", "start": 518, "end": 525, "id": 98 }, { "text": "33258", "start": 526, "end": 531, "id": 99 }, { "text": "(", "start": 532, "end": 533, "id": 100 }, { "text": "see", "start": 533, "end": 536, "id": 101 }, { "text": "Materials", "start": 537, "end": 546, "id": 102 }, { "text": "and", "start": 547, "end": 550, "id": 103 }, { "text": "Methods", "start": 551, "end": 558, "id": 104 }, { "text": ")", "start": 558, "end": 559, "id": 105 }, { "text": ".", "start": 559, "end": 560, "id": 106 }, { "text": "The", "start": 561, "end": 564, "id": 107 }, { "text": "figure", "start": 565, "end": 571, "id": 108 }, { "text": "shows", "start": 572, "end": 577, "id": 109 }, { "text": "fields", "start": 578, "end": 584, "id": 110 }, { "text": "from", "start": 585, "end": 589, "id": 111 }, { "text": "typical", "start": 590, "end": 597, "id": 112 }, { "text": "embryos", "start": 598, "end": 605, "id": 113 }, { "text": "fixed", "start": 606, "end": 611, "id": 114 }, { "text": "10", "start": 612, "end": 614, "id": 115 }, { "text": "(", "start": 615, "end": 616, "id": 116 }, { "text": "A", "start": 616, "end": 617, "id": 117 }, { "text": ")", "start": 617, "end": 618, "id": 118 }, { "text": ",", "start": 618, "end": 619, "id": 119 }, { "text": "45", "start": 620, "end": 622, "id": 120 }, { "text": "(", "start": 623, "end": 624, "id": 121 }, { "text": "B", "start": 624, "end": 625, "id": 122 }, { "text": ")", "start": 625, "end": 626, "id": 123 }, { "text": ",", "start": 626, "end": 627, "id": 124 }, { "text": "and", "start": 628, "end": 631, "id": 125 }, { "text": "90", "start": 632, "end": 634, "id": 126 }, { "text": "(", "start": 635, "end": 636, "id": 127 }, { "text": "C", "start": 636, "end": 637, "id": 128 }, { "text": ")", "start": 637, "end": 638, "id": 129 }, { "text": "min", "start": 639, "end": 642, "id": 130 }, { "text": "after", "start": 643, "end": 648, "id": 131 }, { "text": "injection", "start": 649, "end": 658, "id": 132 }, { "text": "of", "start": 659, "end": 661, "id": 133 }, { "text": "the", "start": 662, "end": 665, "id": 134 }, { "text": "drug", "start": 666, "end": 670, "id": 135 }, { "text": ".", "start": 670, "end": 671, "id": 136 }, { "text": "Bar", "start": 672, "end": 675, "id": 137 }, { "text": ",", "start": 675, "end": 676, "id": 138 }, { "text": "20", "start": 677, "end": 679, "id": 139 }, { "text": "~m", "start": 680, "end": 682, "id": 140 }, { "text": ".", "start": 682, "end": 683, "id": 141 } ]
4be96f3ab2b344cba97d34108118115330086679
Figure2
7-Figure2-1.png
Figure 2 Regional distribution of specific [ 3 H]Ro48 8587 binding (a, b) and expression of GluR1 (c, d) and GluR2 (e, f) in coronal rat brain sections corresponding to Figures 14 and 31 of the rat brain atlas (Paxinos and Watson, 1997). Abbreviations: CA1-3: CA1-3 subfields of the hippocampus; CPu: caudate putamen; DG: dentate gyrus of the hippocampus; LaDL: lateral amygdaloid nucleus, dorsolateral part; MeAm: medial amygdaloid nucleus; NAc; nucleus accumbens; Rt: reticular nucleus of the thalamus.
684
750
{ "a": [ 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "b": [ 2, 3, 4, 17, 18, 19, 20, 21, 22, 23, 24, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "c": [ 2, 3, 4, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "89ac04f1-82ee-44b6-ba74-1e8bd9653cab", "label": "a", "points": [ [ 18.7, 10.7 ], [ 18.7, 232.2 ], [ 672.4, 232.2 ], [ 672.4, 10.7 ] ], "color": "yellow" }, { "id": "ada83d54-40e4-4b8c-a8eb-171855d07dd8", "label": "b", "points": [ [ 20.8, 258.1 ], [ 20.8, 475.3 ], [ 659.4, 475.3 ], [ 659.4, 258.1 ] ], "color": "cyan" }, { "id": "ee79d6fc-6544-4e1b-9f18-da57038f841d", "label": "c", "points": [ [ 15.4, 496.9 ], [ 15.4, 715.1 ], [ 660.5, 715.1 ], [ 660.5, 496.9 ] ], "color": "magenta" }, { "id": "bc05fecb-5b04-4b03-a499-bd0cb3bad353", "label": "c", "points": [ [ 657.3, 711.9 ], [ 657.3, 717.3 ], [ 657.3, 717.3 ], [ 657.3, 711.9 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "2", "start": 7, "end": 8, "id": 1 }, { "text": "Regional", "start": 9, "end": 17, "id": 2 }, { "text": "distribution", "start": 18, "end": 30, "id": 3 }, { "text": "of", "start": 31, "end": 33, "id": 4 }, { "text": "specific", "start": 34, "end": 42, "id": 5 }, { "text": "[", "start": 43, "end": 44, "id": 6 }, { "text": "3", "start": 45, "end": 46, "id": 7 }, { "text": "H]Ro48", "start": 47, "end": 53, "id": 8 }, { "text": "8587", "start": 54, "end": 58, "id": 9 }, { "text": "binding", "start": 59, "end": 66, "id": 10 }, { "text": "(", "start": 67, "end": 68, "id": 11 }, { "text": "a", "start": 68, "end": 69, "id": 12 }, { "text": ",", "start": 69, "end": 70, "id": 13 }, { "text": "b", "start": 71, "end": 72, "id": 14 }, { "text": ")", "start": 72, "end": 73, "id": 15 }, { "text": "and", "start": 74, "end": 77, "id": 16 }, { "text": "expression", "start": 78, "end": 88, "id": 17 }, { "text": "of", "start": 89, "end": 91, "id": 18 }, { "text": "GluR1", "start": 92, "end": 97, "id": 19 }, { "text": "(", "start": 98, "end": 99, "id": 20 }, { "text": "c", "start": 99, "end": 100, "id": 21 }, { "text": ",", "start": 100, "end": 101, "id": 22 }, { "text": "d", "start": 102, "end": 103, "id": 23 }, { "text": ")", "start": 103, "end": 104, "id": 24 }, { "text": "and", "start": 105, "end": 108, "id": 25 }, { "text": "GluR2", "start": 109, "end": 114, "id": 26 }, { "text": "(", "start": 115, "end": 116, "id": 27 }, { "text": "e", "start": 116, "end": 117, "id": 28 }, { "text": ",", "start": 117, "end": 118, "id": 29 }, { "text": "f", "start": 119, "end": 120, "id": 30 }, { "text": ")", "start": 120, "end": 121, "id": 31 }, { "text": "in", "start": 122, "end": 124, "id": 32 }, { "text": "coronal", "start": 125, "end": 132, "id": 33 }, { "text": "rat", "start": 133, "end": 136, "id": 34 }, { "text": "brain", "start": 137, "end": 142, "id": 35 }, { "text": "sections", "start": 143, "end": 151, "id": 36 }, { "text": "corresponding", "start": 152, "end": 165, "id": 37 }, { "text": "to", "start": 166, "end": 168, "id": 38 }, { "text": "Figures", "start": 169, "end": 176, "id": 39 }, { "text": "14", "start": 177, "end": 179, "id": 40 }, { "text": "and", "start": 180, "end": 183, "id": 41 }, { "text": "31", "start": 184, "end": 186, "id": 42 }, { "text": "of", "start": 187, "end": 189, "id": 43 }, { "text": "the", "start": 190, "end": 193, "id": 44 }, { "text": "rat", "start": 194, "end": 197, "id": 45 }, { "text": "brain", "start": 198, "end": 203, "id": 46 }, { "text": "atlas", "start": 204, "end": 209, "id": 47 }, { "text": "(", "start": 210, "end": 211, "id": 48 }, { "text": "Paxinos", "start": 211, "end": 218, "id": 49 }, { "text": "and", "start": 219, "end": 222, "id": 50 }, { "text": "Watson", "start": 223, "end": 229, "id": 51 }, { "text": ",", "start": 229, "end": 230, "id": 52 }, { "text": "1997", "start": 231, "end": 235, "id": 53 }, { "text": ")", "start": 235, "end": 236, "id": 54 }, { "text": ".", "start": 236, "end": 237, "id": 55 }, { "text": "Abbreviations", "start": 238, "end": 251, "id": 56 }, { "text": ":", "start": 251, "end": 252, "id": 57 }, { "text": "CA1", "start": 253, "end": 256, "id": 58 }, { "text": "-", "start": 256, "end": 257, "id": 59 }, { "text": "3", "start": 257, "end": 258, "id": 60 }, { "text": ":", "start": 258, "end": 259, "id": 61 }, { "text": "CA1", "start": 260, "end": 263, "id": 62 }, { "text": "-", "start": 263, "end": 264, "id": 63 }, { "text": "3", "start": 264, "end": 265, "id": 64 }, { "text": "subfields", "start": 266, "end": 275, "id": 65 }, { "text": "of", "start": 276, "end": 278, "id": 66 }, { "text": "the", "start": 279, "end": 282, "id": 67 }, { "text": "hippocampus", "start": 283, "end": 294, "id": 68 }, { "text": ";", "start": 294, "end": 295, "id": 69 }, { "text": "CPu", "start": 296, "end": 299, "id": 70 }, { "text": ":", "start": 299, "end": 300, "id": 71 }, { "text": "caudate", "start": 301, "end": 308, "id": 72 }, { "text": "putamen", "start": 309, "end": 316, "id": 73 }, { "text": ";", "start": 316, "end": 317, "id": 74 }, { "text": "DG", "start": 318, "end": 320, "id": 75 }, { "text": ":", "start": 320, "end": 321, "id": 76 }, { "text": "dentate", "start": 322, "end": 329, "id": 77 }, { "text": "gyrus", "start": 330, "end": 335, "id": 78 }, { "text": "of", "start": 336, "end": 338, "id": 79 }, { "text": "the", "start": 339, "end": 342, "id": 80 }, { "text": "hippocampus", "start": 343, "end": 354, "id": 81 }, { "text": ";", "start": 354, "end": 355, "id": 82 }, { "text": "LaDL", "start": 356, "end": 360, "id": 83 }, { "text": ":", "start": 360, "end": 361, "id": 84 }, { "text": "lateral", "start": 362, "end": 369, "id": 85 }, { "text": "amygdaloid", "start": 370, "end": 380, "id": 86 }, { "text": "nucleus", "start": 381, "end": 388, "id": 87 }, { "text": ",", "start": 388, "end": 389, "id": 88 }, { "text": "dorsolateral", "start": 390, "end": 402, "id": 89 }, { "text": "part", "start": 403, "end": 407, "id": 90 }, { "text": ";", "start": 407, "end": 408, "id": 91 }, { "text": "MeAm", "start": 409, "end": 413, "id": 92 }, { "text": ":", "start": 413, "end": 414, "id": 93 }, { "text": "medial", "start": 415, "end": 421, "id": 94 }, { "text": "amygdaloid", "start": 422, "end": 432, "id": 95 }, { "text": "nucleus", "start": 433, "end": 440, "id": 96 }, { "text": ";", "start": 440, "end": 441, "id": 97 }, { "text": "NAc", "start": 442, "end": 445, "id": 98 }, { "text": ";", "start": 445, "end": 446, "id": 99 }, { "text": "nucleus", "start": 447, "end": 454, "id": 100 }, { "text": "accumbens", "start": 455, "end": 464, "id": 101 }, { "text": ";", "start": 464, "end": 465, "id": 102 }, { "text": "Rt", "start": 466, "end": 468, "id": 103 }, { "text": ":", "start": 468, "end": 469, "id": 104 }, { "text": "reticular", "start": 470, "end": 479, "id": 105 }, { "text": "nucleus", "start": 480, "end": 487, "id": 106 }, { "text": "of", "start": 488, "end": 490, "id": 107 }, { "text": "the", "start": 491, "end": 494, "id": 108 }, { "text": "thalamus", "start": 495, "end": 503, "id": 109 }, { "text": ".", "start": 503, "end": 504, "id": 110 } ]
00c8ad067fbe797981136fa5cf1634d42e25d578
Figure4
4-Figure4-1.png
Figure 4. Images of Case 4. A: MRI shows a hypervascular mass, compatible with angiosarcoma in the right lobe, B: Image shows resected specimen and the site where abscess drainage was performed in his previous surgery, C: Positive immunohistochemical staining for CgA (x200).
1,338
466
{ "a": [ 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23 ], "b": [ 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42 ], "c": [ 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "29c02131-5856-4308-8435-26f0b526d740", "label": "a", "points": [ [ 6.7, 2.8 ], [ 6.7, 444.6 ], [ 437.9, 444.6 ], [ 437.9, 2.8 ] ], "color": "yellow" }, { "id": "4052b81e-f19a-45ad-a4ec-659026f9ca91", "label": "b", "points": [ [ 450.6, 17.6 ], [ 450.6, 442.5 ], [ 890.3, 442.5 ], [ 890.3, 17.6 ] ], "color": "cyan" }, { "id": "18e22bc4-8524-4ba7-a72e-fcec7b2b402d", "label": "c", "points": [ [ 907.2, 17.6 ], [ 907.2, 436.1 ], [ 1336.3, 436.1 ], [ 1336.3, 17.6 ] ], "color": "magenta" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "4", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Images", "start": 10, "end": 16, "id": 3 }, { "text": "of", "start": 17, "end": 19, "id": 4 }, { "text": "Case", "start": 20, "end": 24, "id": 5 }, { "text": "4", "start": 25, "end": 26, "id": 6 }, { "text": ".", "start": 26, "end": 27, "id": 7 }, { "text": "A", "start": 28, "end": 29, "id": 8 }, { "text": ":", "start": 29, "end": 30, "id": 9 }, { "text": "MRI", "start": 31, "end": 34, "id": 10 }, { "text": "shows", "start": 35, "end": 40, "id": 11 }, { "text": "a", "start": 41, "end": 42, "id": 12 }, { "text": "hypervascular", "start": 43, "end": 56, "id": 13 }, { "text": "mass", "start": 57, "end": 61, "id": 14 }, { "text": ",", "start": 61, "end": 62, "id": 15 }, { "text": "compatible", "start": 63, "end": 73, "id": 16 }, { "text": "with", "start": 74, "end": 78, "id": 17 }, { "text": "angiosarcoma", "start": 79, "end": 91, "id": 18 }, { "text": "in", "start": 92, "end": 94, "id": 19 }, { "text": "the", "start": 95, "end": 98, "id": 20 }, { "text": "right", "start": 99, "end": 104, "id": 21 }, { "text": "lobe", "start": 105, "end": 109, "id": 22 }, { "text": ",", "start": 109, "end": 110, "id": 23 }, { "text": "B", "start": 111, "end": 112, "id": 24 }, { "text": ":", "start": 112, "end": 113, "id": 25 }, { "text": "Image", "start": 114, "end": 119, "id": 26 }, { "text": "shows", "start": 120, "end": 125, "id": 27 }, { "text": "resected", "start": 126, "end": 134, "id": 28 }, { "text": "specimen", "start": 135, "end": 143, "id": 29 }, { "text": "and", "start": 144, "end": 147, "id": 30 }, { "text": "the", "start": 148, "end": 151, "id": 31 }, { "text": "site", "start": 152, "end": 156, "id": 32 }, { "text": "where", "start": 157, "end": 162, "id": 33 }, { "text": "abscess", "start": 163, "end": 170, "id": 34 }, { "text": "drainage", "start": 171, "end": 179, "id": 35 }, { "text": "was", "start": 180, "end": 183, "id": 36 }, { "text": "performed", "start": 184, "end": 193, "id": 37 }, { "text": "in", "start": 194, "end": 196, "id": 38 }, { "text": "his", "start": 197, "end": 200, "id": 39 }, { "text": "previous", "start": 201, "end": 209, "id": 40 }, { "text": "surgery", "start": 210, "end": 217, "id": 41 }, { "text": ",", "start": 217, "end": 218, "id": 42 }, { "text": "C", "start": 219, "end": 220, "id": 43 }, { "text": ":", "start": 220, "end": 221, "id": 44 }, { "text": "Positive", "start": 222, "end": 230, "id": 45 }, { "text": "immunohistochemical", "start": 231, "end": 250, "id": 46 }, { "text": "staining", "start": 251, "end": 259, "id": 47 }, { "text": "for", "start": 260, "end": 263, "id": 48 }, { "text": "CgA", "start": 264, "end": 267, "id": 49 }, { "text": "(", "start": 268, "end": 269, "id": 50 }, { "text": "x200", "start": 269, "end": 273, "id": 51 }, { "text": ")", "start": 273, "end": 274, "id": 52 }, { "text": ".", "start": 274, "end": 275, "id": 53 } ]
400e166023e6a8fbf78a3757b6c4e5233d637b41
Figure2
2-Figure2-1.png
Fig. 2 – T1-weighted axial (A), T2-weighted coronal (B), T2-weighted axial (C), and axial fluid-attenuated inversion recovery sequence (D) of magnetic resonance images show ventriculomegaly, cystic encephalomalacia, and extensive subcortical and periventricular white matter loss and hyperintensity in white matter with atrophy.
834
886
{ "a": [ 4, 5, 6, 7, 8, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58 ], "b": [ 10, 11, 12, 13, 14, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58 ], "c": [ 16, 17, 18, 19, 20, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58 ], "d": [ 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "c57e207a-8352-447d-b3a6-746a52266958", "label": "a", "points": [ [ 10.5, 0 ], [ 10.5, 426.9 ], [ 417.7, 426.9 ], [ 417.7, 0 ] ], "color": "yellow" }, { "id": "d25ffb54-3abc-402f-a0d2-af0cdcd04955", "label": "c", "points": [ [ 11.9, 444 ], [ 11.9, 881.5 ], [ 407.1, 881.5 ], [ 407.1, 444 ] ], "color": "magenta" }, { "id": "2cee99ab-ece5-4783-b3ca-24fb2c6f7784", "label": "d", "points": [ [ 421.6, 445.3 ], [ 421.6, 882.8 ], [ 827.4, 882.8 ], [ 827.4, 445.3 ] ], "color": "tomato" }, { "id": "6784ac21-5457-49ac-9acc-91ef3930d03f", "label": "b", "points": [ [ 425.9, 6.2 ], [ 425.9, 431.1 ], [ 827.1, 431.1 ], [ 827.1, 6.2 ] ], "color": "springgreen" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "2", "start": 5, "end": 6, "id": 2 }, { "text": "–", "start": 7, "end": 8, "id": 3 }, { "text": "T1-weighted", "start": 9, "end": 20, "id": 4 }, { "text": "axial", "start": 21, "end": 26, "id": 5 }, { "text": "(", "start": 27, "end": 28, "id": 6 }, { "text": "A", "start": 28, "end": 29, "id": 7 }, { "text": ")", "start": 29, "end": 30, "id": 8 }, { "text": ",", "start": 30, "end": 31, "id": 9 }, { "text": "T2-weighted", "start": 32, "end": 43, "id": 10 }, { "text": "coronal", "start": 44, "end": 51, "id": 11 }, { "text": "(", "start": 52, "end": 53, "id": 12 }, { "text": "B", "start": 53, "end": 54, "id": 13 }, { "text": ")", "start": 54, "end": 55, "id": 14 }, { "text": ",", "start": 55, "end": 56, "id": 15 }, { "text": "T2-weighted", "start": 57, "end": 68, "id": 16 }, { "text": "axial", "start": 69, "end": 74, "id": 17 }, { "text": "(", "start": 75, "end": 76, "id": 18 }, { "text": "C", "start": 76, "end": 77, "id": 19 }, { "text": ")", "start": 77, "end": 78, "id": 20 }, { "text": ",", "start": 78, "end": 79, "id": 21 }, { "text": "and", "start": 80, "end": 83, "id": 22 }, { "text": "axial", "start": 84, "end": 89, "id": 23 }, { "text": "fluid", "start": 90, "end": 95, "id": 24 }, { "text": "-", "start": 95, "end": 96, "id": 25 }, { "text": "attenuated", "start": 96, "end": 106, "id": 26 }, { "text": "inversion", "start": 107, "end": 116, "id": 27 }, { "text": "recovery", "start": 117, "end": 125, "id": 28 }, { "text": "sequence", "start": 126, "end": 134, "id": 29 }, { "text": "(", "start": 135, "end": 136, "id": 30 }, { "text": "D", "start": 136, "end": 137, "id": 31 }, { "text": ")", "start": 137, "end": 138, "id": 32 }, { "text": "of", "start": 139, "end": 141, "id": 33 }, { "text": "magnetic", "start": 142, "end": 150, "id": 34 }, { "text": "resonance", "start": 151, "end": 160, "id": 35 }, { "text": "images", "start": 161, "end": 167, "id": 36 }, { "text": "show", "start": 168, "end": 172, "id": 37 }, { "text": "ventriculomegaly", "start": 173, "end": 189, "id": 38 }, { "text": ",", "start": 189, "end": 190, "id": 39 }, { "text": "cystic", "start": 191, "end": 197, "id": 40 }, { "text": "encephalomalacia", "start": 198, "end": 214, "id": 41 }, { "text": ",", "start": 214, "end": 215, "id": 42 }, { "text": "and", "start": 216, "end": 219, "id": 43 }, { "text": "extensive", "start": 220, "end": 229, "id": 44 }, { "text": "subcortical", "start": 230, "end": 241, "id": 45 }, { "text": "and", "start": 242, "end": 245, "id": 46 }, { "text": "periventricular", "start": 246, "end": 261, "id": 47 }, { "text": "white", "start": 262, "end": 267, "id": 48 }, { "text": "matter", "start": 268, "end": 274, "id": 49 }, { "text": "loss", "start": 275, "end": 279, "id": 50 }, { "text": "and", "start": 280, "end": 283, "id": 51 }, { "text": "hyperintensity", "start": 284, "end": 298, "id": 52 }, { "text": "in", "start": 299, "end": 301, "id": 53 }, { "text": "white", "start": 302, "end": 307, "id": 54 }, { "text": "matter", "start": 308, "end": 314, "id": 55 }, { "text": "with", "start": 315, "end": 319, "id": 56 }, { "text": "atrophy", "start": 320, "end": 327, "id": 57 }, { "text": ".", "start": 327, "end": 328, "id": 58 } ]
1aed386aecbd7c98e2a31c280d5f4194ab45768a
Figure7
9-Figure7-1.png
Figure 7. Localization of ‘H-DPR * ., ,. , I’ 6 .J (top), 3H-NBI (middle), and ‘H-CHA (bottom) binding sites in adjacent coronal sections in the plane of the hippocampus of a pointer dog brain. The distribution of all 3 binding sites is very similar to their distribution in guinea pig brain. The only remarkable difference is their practically identical localization in layers of Ammon’s horn (H), and dentate gyrus (DC). Other structures shown are parietal cortex (CC), superior colliculus (superficial gray, SG), central gray (CG), medial geniculate body (GB), and substantia nigra (,!W). Sections labeled with 3H-NBI and ‘HCHA were exposed for 8 weeks together with the corresponding sections in Figure 8 because of the relative low binding densities and the low specific activity of the radiolabels as contrasted to the 3H-DPR sections, which were again exposed for 4 weeks. Ligand concentrations were 2.5 nM for )H-DPR, 0.4 11~ for 3H-NBI, and 5 nM for ‘H-CHA.
836
1,726
{ "a": [ 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "b": [ 3, 4, 23, 24, 25, 26, 27, 28, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "c": [ 3, 4, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "9e7c9e26-d1ba-4a35-a03a-006fa8d98838", "label": "a", "points": [ [ 5.5, 0 ], [ 5.5, 561.3 ], [ 830.9, 561.3 ], [ 830.9, 0 ] ], "color": "yellow" }, { "id": "ad5c2915-77d0-4139-9f81-cee13a16059f", "label": "b", "points": [ [ 9.5, 581.6 ], [ 9.5, 1131 ], [ 828.3, 1131 ], [ 828.3, 581.6 ] ], "color": "cyan" }, { "id": "e14fa083-b845-4773-80bc-8c8ef5b65db3", "label": "c", "points": [ [ 12.1, 1165.7 ], [ 12.1, 1719.1 ], [ 833.6, 1719.1 ], [ 833.6, 1165.7 ] ], "color": "magenta" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "7", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Localization", "start": 10, "end": 22, "id": 3 }, { "text": "of", "start": 23, "end": 25, "id": 4 }, { "text": "‘", "start": 26, "end": 27, "id": 5 }, { "text": "H", "start": 27, "end": 28, "id": 6 }, { "text": "-", "start": 28, "end": 29, "id": 7 }, { "text": "DPR", "start": 29, "end": 32, "id": 8 }, { "text": "*", "start": 33, "end": 34, "id": 9 }, { "text": ".", "start": 35, "end": 36, "id": 10 }, { "text": ",", "start": 36, "end": 37, "id": 11 }, { "text": ",", "start": 38, "end": 39, "id": 12 }, { "text": ".", "start": 39, "end": 40, "id": 13 }, { "text": ",", "start": 41, "end": 42, "id": 14 }, { "text": "I", "start": 43, "end": 44, "id": 15 }, { "text": "’", "start": 44, "end": 45, "id": 16 }, { "text": "6", "start": 46, "end": 47, "id": 17 }, { "text": ".J", "start": 48, "end": 50, "id": 18 }, { "text": "(", "start": 51, "end": 52, "id": 19 }, { "text": "top", "start": 52, "end": 55, "id": 20 }, { "text": ")", "start": 55, "end": 56, "id": 21 }, { "text": ",", "start": 56, "end": 57, "id": 22 }, { "text": "3H", "start": 58, "end": 60, "id": 23 }, { "text": "-", "start": 60, "end": 61, "id": 24 }, { "text": "NBI", "start": 61, "end": 64, "id": 25 }, { "text": "(", "start": 65, "end": 66, "id": 26 }, { "text": "middle", "start": 66, "end": 72, "id": 27 }, { "text": ")", "start": 72, "end": 73, "id": 28 }, { "text": ",", "start": 73, "end": 74, "id": 29 }, { "text": "and", "start": 75, "end": 78, "id": 30 }, { "text": "‘", "start": 79, "end": 80, "id": 31 }, { "text": "H", "start": 80, "end": 81, "id": 32 }, { "text": "-", "start": 81, "end": 82, "id": 33 }, { "text": "CHA", "start": 82, "end": 85, "id": 34 }, { "text": "(", "start": 86, "end": 87, "id": 35 }, { "text": "bottom", "start": 87, "end": 93, "id": 36 }, { "text": ")", "start": 93, "end": 94, "id": 37 }, { "text": "binding", "start": 95, "end": 102, "id": 38 }, { "text": "sites", "start": 103, "end": 108, "id": 39 }, { "text": "in", "start": 109, "end": 111, "id": 40 }, { "text": "adjacent", "start": 112, "end": 120, "id": 41 }, { "text": "coronal", "start": 121, "end": 128, "id": 42 }, { "text": "sections", "start": 129, "end": 137, "id": 43 }, { "text": "in", "start": 138, "end": 140, "id": 44 }, { "text": "the", "start": 141, "end": 144, "id": 45 }, { "text": "plane", "start": 145, "end": 150, "id": 46 }, { "text": "of", "start": 151, "end": 153, "id": 47 }, { "text": "the", "start": 154, "end": 157, "id": 48 }, { "text": "hippocampus", "start": 158, "end": 169, "id": 49 }, { "text": "of", "start": 170, "end": 172, "id": 50 }, { "text": "a", "start": 173, "end": 174, "id": 51 }, { "text": "pointer", "start": 175, "end": 182, "id": 52 }, { "text": "dog", "start": 183, "end": 186, "id": 53 }, { "text": "brain", "start": 187, "end": 192, "id": 54 }, { "text": ".", "start": 192, "end": 193, "id": 55 }, { "text": "The", "start": 194, "end": 197, "id": 56 }, { "text": "distribution", "start": 198, "end": 210, "id": 57 }, { "text": "of", "start": 211, "end": 213, "id": 58 }, { "text": "all", "start": 214, "end": 217, "id": 59 }, { "text": "3", "start": 218, "end": 219, "id": 60 }, { "text": "binding", "start": 220, "end": 227, "id": 61 }, { "text": "sites", "start": 228, "end": 233, "id": 62 }, { "text": "is", "start": 234, "end": 236, "id": 63 }, { "text": "very", "start": 237, "end": 241, "id": 64 }, { "text": "similar", "start": 242, "end": 249, "id": 65 }, { "text": "to", "start": 250, "end": 252, "id": 66 }, { "text": "their", "start": 253, "end": 258, "id": 67 }, { "text": "distribution", "start": 259, "end": 271, "id": 68 }, { "text": "in", "start": 272, "end": 274, "id": 69 }, { "text": "guinea", "start": 275, "end": 281, "id": 70 }, { "text": "pig", "start": 282, "end": 285, "id": 71 }, { "text": "brain", "start": 286, "end": 291, "id": 72 }, { "text": ".", "start": 291, "end": 292, "id": 73 }, { "text": "The", "start": 293, "end": 296, "id": 74 }, { "text": "only", "start": 297, "end": 301, "id": 75 }, { "text": "remarkable", "start": 302, "end": 312, "id": 76 }, { "text": "difference", "start": 313, "end": 323, "id": 77 }, { "text": "is", "start": 324, "end": 326, "id": 78 }, { "text": "their", "start": 327, "end": 332, "id": 79 }, { "text": "practically", "start": 333, "end": 344, "id": 80 }, { "text": "identical", "start": 345, "end": 354, "id": 81 }, { "text": "localization", "start": 355, "end": 367, "id": 82 }, { "text": "in", "start": 368, "end": 370, "id": 83 }, { "text": "layers", "start": 371, "end": 377, "id": 84 }, { "text": "of", "start": 378, "end": 380, "id": 85 }, { "text": "Ammon", "start": 381, "end": 386, "id": 86 }, { "text": "’s", "start": 386, "end": 388, "id": 87 }, { "text": "horn", "start": 389, "end": 393, "id": 88 }, { "text": "(", "start": 394, "end": 395, "id": 89 }, { "text": "H", "start": 395, "end": 396, "id": 90 }, { "text": ")", "start": 396, "end": 397, "id": 91 }, { "text": ",", "start": 397, "end": 398, "id": 92 }, { "text": "and", "start": 399, "end": 402, "id": 93 }, { "text": "dentate", "start": 403, "end": 410, "id": 94 }, { "text": "gyrus", "start": 411, "end": 416, "id": 95 }, { "text": "(", "start": 417, "end": 418, "id": 96 }, { "text": "DC", "start": 418, "end": 420, "id": 97 }, { "text": ")", "start": 420, "end": 421, "id": 98 }, { "text": ".", "start": 421, "end": 422, "id": 99 }, { "text": "Other", "start": 423, "end": 428, "id": 100 }, { "text": "structures", "start": 429, "end": 439, "id": 101 }, { "text": "shown", "start": 440, "end": 445, "id": 102 }, { "text": "are", "start": 446, "end": 449, "id": 103 }, { "text": "parietal", "start": 450, "end": 458, "id": 104 }, { "text": "cortex", "start": 459, "end": 465, "id": 105 }, { "text": "(", "start": 466, "end": 467, "id": 106 }, { "text": "CC", "start": 467, "end": 469, "id": 107 }, { "text": ")", "start": 469, "end": 470, "id": 108 }, { "text": ",", "start": 470, "end": 471, "id": 109 }, { "text": "superior", "start": 472, "end": 480, "id": 110 }, { "text": "colliculus", "start": 481, "end": 491, "id": 111 }, { "text": "(", "start": 492, "end": 493, "id": 112 }, { "text": "superficial", "start": 493, "end": 504, "id": 113 }, { "text": "gray", "start": 505, "end": 509, "id": 114 }, { "text": ",", "start": 509, "end": 510, "id": 115 }, { "text": "SG", "start": 511, "end": 513, "id": 116 }, { "text": ")", "start": 513, "end": 514, "id": 117 }, { "text": ",", "start": 514, "end": 515, "id": 118 }, { "text": "central", "start": 516, "end": 523, "id": 119 }, { "text": "gray", "start": 524, "end": 528, "id": 120 }, { "text": "(", "start": 529, "end": 530, "id": 121 }, { "text": "CG", "start": 530, "end": 532, "id": 122 }, { "text": ")", "start": 532, "end": 533, "id": 123 }, { "text": ",", "start": 533, "end": 534, "id": 124 }, { "text": "medial", "start": 535, "end": 541, "id": 125 }, { "text": "geniculate", "start": 542, "end": 552, "id": 126 }, { "text": "body", "start": 553, "end": 557, "id": 127 }, { "text": "(", "start": 558, "end": 559, "id": 128 }, { "text": "GB", "start": 559, "end": 561, "id": 129 }, { "text": ")", "start": 561, "end": 562, "id": 130 }, { "text": ",", "start": 562, "end": 563, "id": 131 }, { "text": "and", "start": 564, "end": 567, "id": 132 }, { "text": "substantia", "start": 568, "end": 578, "id": 133 }, { "text": "nigra", "start": 579, "end": 584, "id": 134 }, { "text": "(", "start": 585, "end": 586, "id": 135 }, { "text": ",", "start": 586, "end": 587, "id": 136 }, { "text": "!", "start": 587, "end": 588, "id": 137 }, { "text": "W", "start": 588, "end": 589, "id": 138 }, { "text": ")", "start": 589, "end": 590, "id": 139 }, { "text": ".", "start": 590, "end": 591, "id": 140 }, { "text": "Sections", "start": 592, "end": 600, "id": 141 }, { "text": "labeled", "start": 601, "end": 608, "id": 142 }, { "text": "with", "start": 609, "end": 613, "id": 143 }, { "text": "3H", "start": 614, "end": 616, "id": 144 }, { "text": "-", "start": 616, "end": 617, "id": 145 }, { "text": "NBI", "start": 617, "end": 620, "id": 146 }, { "text": "and", "start": 621, "end": 624, "id": 147 }, { "text": "‘", "start": 625, "end": 626, "id": 148 }, { "text": "HCHA", "start": 626, "end": 630, "id": 149 }, { "text": "were", "start": 631, "end": 635, "id": 150 }, { "text": "exposed", "start": 636, "end": 643, "id": 151 }, { "text": "for", "start": 644, "end": 647, "id": 152 }, { "text": "8", "start": 648, "end": 649, "id": 153 }, { "text": "weeks", "start": 650, "end": 655, "id": 154 }, { "text": "together", "start": 656, "end": 664, "id": 155 }, { "text": "with", "start": 665, "end": 669, "id": 156 }, { "text": "the", "start": 670, "end": 673, "id": 157 }, { "text": "corresponding", "start": 674, "end": 687, "id": 158 }, { "text": "sections", "start": 688, "end": 696, "id": 159 }, { "text": "in", "start": 697, "end": 699, "id": 160 }, { "text": "Figure", "start": 700, "end": 706, "id": 161 }, { "text": "8", "start": 707, "end": 708, "id": 162 }, { "text": "because", "start": 709, "end": 716, "id": 163 }, { "text": "of", "start": 717, "end": 719, "id": 164 }, { "text": "the", "start": 720, "end": 723, "id": 165 }, { "text": "relative", "start": 724, "end": 732, "id": 166 }, { "text": "low", "start": 733, "end": 736, "id": 167 }, { "text": "binding", "start": 737, "end": 744, "id": 168 }, { "text": "densities", "start": 745, "end": 754, "id": 169 }, { "text": "and", "start": 755, "end": 758, "id": 170 }, { "text": "the", "start": 759, "end": 762, "id": 171 }, { "text": "low", "start": 763, "end": 766, "id": 172 }, { "text": "specific", "start": 767, "end": 775, "id": 173 }, { "text": "activity", "start": 776, "end": 784, "id": 174 }, { "text": "of", "start": 785, "end": 787, "id": 175 }, { "text": "the", "start": 788, "end": 791, "id": 176 }, { "text": "radiolabels", "start": 792, "end": 803, "id": 177 }, { "text": "as", "start": 804, "end": 806, "id": 178 }, { "text": "contrasted", "start": 807, "end": 817, "id": 179 }, { "text": "to", "start": 818, "end": 820, "id": 180 }, { "text": "the", "start": 821, "end": 824, "id": 181 }, { "text": "3H", "start": 825, "end": 827, "id": 182 }, { "text": "-", "start": 827, "end": 828, "id": 183 }, { "text": "DPR", "start": 828, "end": 831, "id": 184 }, { "text": "sections", "start": 832, "end": 840, "id": 185 }, { "text": ",", "start": 840, "end": 841, "id": 186 }, { "text": "which", "start": 842, "end": 847, "id": 187 }, { "text": "were", "start": 848, "end": 852, "id": 188 }, { "text": "again", "start": 853, "end": 858, "id": 189 }, { "text": "exposed", "start": 859, "end": 866, "id": 190 }, { "text": "for", "start": 867, "end": 870, "id": 191 }, { "text": "4", "start": 871, "end": 872, "id": 192 }, { "text": "weeks", "start": 873, "end": 878, "id": 193 }, { "text": ".", "start": 878, "end": 879, "id": 194 }, { "text": "Ligand", "start": 880, "end": 886, "id": 195 }, { "text": "concentrations", "start": 887, "end": 901, "id": 196 }, { "text": "were", "start": 902, "end": 906, "id": 197 }, { "text": "2.5", "start": 907, "end": 910, "id": 198 }, { "text": "nM", "start": 911, "end": 913, "id": 199 }, { "text": "for", "start": 914, "end": 917, "id": 200 }, { "text": ")", "start": 918, "end": 919, "id": 201 }, { "text": "H", "start": 919, "end": 920, "id": 202 }, { "text": "-", "start": 920, "end": 921, "id": 203 }, { "text": "DPR", "start": 921, "end": 924, "id": 204 }, { "text": ",", "start": 924, "end": 925, "id": 205 }, { "text": "0.4", "start": 926, "end": 929, "id": 206 }, { "text": "11~", "start": 930, "end": 933, "id": 207 }, { "text": "for", "start": 934, "end": 937, "id": 208 }, { "text": "3H", "start": 938, "end": 940, "id": 209 }, { "text": "-", "start": 940, "end": 941, "id": 210 }, { "text": "NBI", "start": 941, "end": 944, "id": 211 }, { "text": ",", "start": 944, "end": 945, "id": 212 }, { "text": "and", "start": 946, "end": 949, "id": 213 }, { "text": "5", "start": 950, "end": 951, "id": 214 }, { "text": "nM", "start": 952, "end": 954, "id": 215 }, { "text": "for", "start": 955, "end": 958, "id": 216 }, { "text": "‘", "start": 959, "end": 960, "id": 217 }, { "text": "H", "start": 960, "end": 961, "id": 218 }, { "text": "-", "start": 961, "end": 962, "id": 219 }, { "text": "CHA", "start": 962, "end": 965, "id": 220 }, { "text": ".", "start": 965, "end": 966, "id": 221 } ]
fa6f0db8aec6efbf332a215397b68c07c4cace09
Figure13
15-Figure13-1.png
Fig 13. Isolation of canine glioma-targeting peptides for delivery of imaging and therapeutic agents. Tumor-specific peptides have many advantages over more traditional antibody based targeting strategies. (A) Canine glioma cells bind to bead-specific peptide sequences in random screening libraries. (B, C) Isolation of bead peptides and conjugation to fluorescent markers allows targeting to canine glioma tumors grown in mouse subcutaneous models.
906
582
{ "a": [ 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50 ], "b": [ 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "732255d0-164b-4111-8083-811c33326adf", "label": "a", "points": [ [ 5, 3 ], [ 5, 576.9 ], [ 312.7, 576.9 ], [ 312.7, 3 ] ], "color": "yellow" }, { "id": "cee04e24-22c6-4e46-8c92-5783866270f6", "label": "b", "points": [ [ 322.8, 3 ], [ 322.8, 576.9 ], [ 604.7, 576.9 ], [ 604.7, 3 ] ], "color": "cyan" }, { "id": "0b99ddbe-65ab-4e1f-a9d1-30c27cba8346", "label": "b", "points": [ [ 619, -1.3 ], [ 619, 576.9 ], [ 902.4, 576.9 ], [ 902.4, -1.3 ] ], "color": "magenta" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": "13", "start": 4, "end": 6, "id": 1 }, { "text": ".", "start": 6, "end": 7, "id": 2 }, { "text": "Isolation", "start": 8, "end": 17, "id": 3 }, { "text": "of", "start": 18, "end": 20, "id": 4 }, { "text": "canine", "start": 21, "end": 27, "id": 5 }, { "text": "glioma", "start": 28, "end": 34, "id": 6 }, { "text": "-", "start": 34, "end": 35, "id": 7 }, { "text": "targeting", "start": 35, "end": 44, "id": 8 }, { "text": "peptides", "start": 45, "end": 53, "id": 9 }, { "text": "for", "start": 54, "end": 57, "id": 10 }, { "text": "delivery", "start": 58, "end": 66, "id": 11 }, { "text": "of", "start": 67, "end": 69, "id": 12 }, { "text": "imaging", "start": 70, "end": 77, "id": 13 }, { "text": "and", "start": 78, "end": 81, "id": 14 }, { "text": "therapeutic", "start": 82, "end": 93, "id": 15 }, { "text": "agents", "start": 94, "end": 100, "id": 16 }, { "text": ".", "start": 100, "end": 101, "id": 17 }, { "text": "Tumor", "start": 102, "end": 107, "id": 18 }, { "text": "-", "start": 107, "end": 108, "id": 19 }, { "text": "specific", "start": 108, "end": 116, "id": 20 }, { "text": "peptides", "start": 117, "end": 125, "id": 21 }, { "text": "have", "start": 126, "end": 130, "id": 22 }, { "text": "many", "start": 131, "end": 135, "id": 23 }, { "text": "advantages", "start": 136, "end": 146, "id": 24 }, { "text": "over", "start": 147, "end": 151, "id": 25 }, { "text": "more", "start": 152, "end": 156, "id": 26 }, { "text": "traditional", "start": 157, "end": 168, "id": 27 }, { "text": "antibody", "start": 169, "end": 177, "id": 28 }, { "text": "based", "start": 178, "end": 183, "id": 29 }, { "text": "targeting", "start": 184, "end": 193, "id": 30 }, { "text": "strategies", "start": 194, "end": 204, "id": 31 }, { "text": ".", "start": 204, "end": 205, "id": 32 }, { "text": "(", "start": 206, "end": 207, "id": 33 }, { "text": "A", "start": 207, "end": 208, "id": 34 }, { "text": ")", "start": 208, "end": 209, "id": 35 }, { "text": "Canine", "start": 210, "end": 216, "id": 36 }, { "text": "glioma", "start": 217, "end": 223, "id": 37 }, { "text": "cells", "start": 224, "end": 229, "id": 38 }, { "text": "bind", "start": 230, "end": 234, "id": 39 }, { "text": "to", "start": 235, "end": 237, "id": 40 }, { "text": "bead", "start": 238, "end": 242, "id": 41 }, { "text": "-", "start": 242, "end": 243, "id": 42 }, { "text": "specific", "start": 243, "end": 251, "id": 43 }, { "text": "peptide", "start": 252, "end": 259, "id": 44 }, { "text": "sequences", "start": 260, "end": 269, "id": 45 }, { "text": "in", "start": 270, "end": 272, "id": 46 }, { "text": "random", "start": 273, "end": 279, "id": 47 }, { "text": "screening", "start": 280, "end": 289, "id": 48 }, { "text": "libraries", "start": 290, "end": 299, "id": 49 }, { "text": ".", "start": 299, "end": 300, "id": 50 }, { "text": "(", "start": 301, "end": 302, "id": 51 }, { "text": "B", "start": 302, "end": 303, "id": 52 }, { "text": ",", "start": 303, "end": 304, "id": 53 }, { "text": "C", "start": 305, "end": 306, "id": 54 }, { "text": ")", "start": 306, "end": 307, "id": 55 }, { "text": "Isolation", "start": 308, "end": 317, "id": 56 }, { "text": "of", "start": 318, "end": 320, "id": 57 }, { "text": "bead", "start": 321, "end": 325, "id": 58 }, { "text": "peptides", "start": 326, "end": 334, "id": 59 }, { "text": "and", "start": 335, "end": 338, "id": 60 }, { "text": "conjugation", "start": 339, "end": 350, "id": 61 }, { "text": "to", "start": 351, "end": 353, "id": 62 }, { "text": "fluorescent", "start": 354, "end": 365, "id": 63 }, { "text": "markers", "start": 366, "end": 373, "id": 64 }, { "text": "allows", "start": 374, "end": 380, "id": 65 }, { "text": "targeting", "start": 381, "end": 390, "id": 66 }, { "text": "to", "start": 391, "end": 393, "id": 67 }, { "text": "canine", "start": 394, "end": 400, "id": 68 }, { "text": "glioma", "start": 401, "end": 407, "id": 69 }, { "text": "tumors", "start": 408, "end": 414, "id": 70 }, { "text": "grown", "start": 415, "end": 420, "id": 71 }, { "text": "in", "start": 421, "end": 423, "id": 72 }, { "text": "mouse", "start": 424, "end": 429, "id": 73 }, { "text": "subcutaneous", "start": 430, "end": 442, "id": 74 }, { "text": "models", "start": 443, "end": 449, "id": 75 }, { "text": ".", "start": 449, "end": 450, "id": 76 } ]
b5d9875a7861facd304f0b53cf29f6aa5637ee08
Figure8
12-Figure8-1.png
Fig. 8. Label in olfactory tubercle ( O n ) after injection of C2 in animal 93. A. cresyl violet. B. darkfield photomicrograph of coronal nection in (A). Compare to Figure 2B, C.
512
1,504
{ "a": [ 20, 21, 22, 23 ], "b": [ 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "8bd84315-975b-4dfc-b69d-11af5a0e953a", "label": "a", "points": [ [ 4.8, 756.9 ], [ 4.8, 1501.9 ], [ 505.8, 1501.9 ], [ 505.8, 756.9 ] ], "color": "yellow" }, { "id": "97ce2ae3-b694-49b2-be27-654cf956de63", "label": "b", "points": [ [ 1.8, 1.9 ], [ 1.8, 744.9 ], [ 523.8, 744.9 ], [ 523.8, 1.9 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "8", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "Label", "start": 8, "end": 13, "id": 4 }, { "text": "in", "start": 14, "end": 16, "id": 5 }, { "text": "olfactory", "start": 17, "end": 26, "id": 6 }, { "text": "tubercle", "start": 27, "end": 35, "id": 7 }, { "text": "(", "start": 36, "end": 37, "id": 8 }, { "text": "O", "start": 38, "end": 39, "id": 9 }, { "text": "n", "start": 40, "end": 41, "id": 10 }, { "text": ")", "start": 42, "end": 43, "id": 11 }, { "text": "after", "start": 44, "end": 49, "id": 12 }, { "text": "injection", "start": 50, "end": 59, "id": 13 }, { "text": "of", "start": 60, "end": 62, "id": 14 }, { "text": "C2", "start": 63, "end": 65, "id": 15 }, { "text": "in", "start": 66, "end": 68, "id": 16 }, { "text": "animal", "start": 69, "end": 75, "id": 17 }, { "text": "93", "start": 76, "end": 78, "id": 18 }, { "text": ".", "start": 78, "end": 79, "id": 19 }, { "text": "A.", "start": 80, "end": 82, "id": 20 }, { "text": "cresyl", "start": 83, "end": 89, "id": 21 }, { "text": "violet", "start": 90, "end": 96, "id": 22 }, { "text": ".", "start": 96, "end": 97, "id": 23 }, { "text": "B.", "start": 98, "end": 100, "id": 24 }, { "text": "darkfield", "start": 101, "end": 110, "id": 25 }, { "text": "photomicrograph", "start": 111, "end": 126, "id": 26 }, { "text": "of", "start": 127, "end": 129, "id": 27 }, { "text": "coronal", "start": 130, "end": 137, "id": 28 }, { "text": "nection", "start": 138, "end": 145, "id": 29 }, { "text": "in", "start": 146, "end": 148, "id": 30 }, { "text": "(", "start": 149, "end": 150, "id": 31 }, { "text": "A", "start": 150, "end": 151, "id": 32 }, { "text": ")", "start": 151, "end": 152, "id": 33 }, { "text": ".", "start": 152, "end": 153, "id": 34 }, { "text": "Compare", "start": 154, "end": 161, "id": 35 }, { "text": "to", "start": 162, "end": 164, "id": 36 }, { "text": "Figure", "start": 165, "end": 171, "id": 37 }, { "text": "2B", "start": 172, "end": 174, "id": 38 }, { "text": ",", "start": 174, "end": 175, "id": 39 }, { "text": "C.", "start": 176, "end": 178, "id": 40 } ]
6b18be6e9ec907ff2544ca95046efc882a6b2484
Figure1
7-Figure1-1.png
Figure 1. Expression of Gli-1 and Gli-2. Nuclear staining of Gli-1 in (A) a trabecular pattern and (B) a pseudoacinar pattern in HCC tissues, in contrast to normal liver tissue (inset of A). Strong and diffuse nuclear staining of Gli-2 in (C) a trabecular pattern and (D) a pseudoacinar pattern in HCC tissues, in comparison to adjacent normal liver parenchyme (inset of C). HCC, hepatocellular carcinoma. Magnification A-D, x20.
1,108
864
{ "a": [ 14, 15, 16, 17, 18, 19 ], "b": [ 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36 ], "c": [ 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56 ], "d": [ 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "4577463e-e607-4525-91d9-51f2e214fd39", "label": "a", "points": [ [ 6.1, 12.3 ], [ 6.1, 413.1 ], [ 531.3, 413.1 ], [ 531.3, 12.3 ] ], "color": "yellow" }, { "id": "a5a7a5eb-3346-49f0-84fe-aa089051f5ea", "label": "b", "points": [ [ 576.8, 7 ], [ 576.8, 409.6 ], [ 1096.6, 409.6 ], [ 1096.6, 7 ] ], "color": "cyan" }, { "id": "449828e2-905d-47e2-85c7-5ade1ae8bd12", "label": "c", "points": [ [ 4.4, 449.9 ], [ 4.4, 852.5 ], [ 531.3, 852.5 ], [ 531.3, 449.9 ] ], "color": "magenta" }, { "id": "4921407f-9802-4df7-8a75-bfebb10a86f2", "label": "d", "points": [ [ 573.3, 448.1 ], [ 573.3, 856 ], [ 1091.4, 856 ], [ 1091.4, 448.1 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Expression", "start": 10, "end": 20, "id": 3 }, { "text": "of", "start": 21, "end": 23, "id": 4 }, { "text": "Gli-1", "start": 24, "end": 29, "id": 5 }, { "text": "and", "start": 30, "end": 33, "id": 6 }, { "text": "Gli-2", "start": 34, "end": 39, "id": 7 }, { "text": ".", "start": 39, "end": 40, "id": 8 }, { "text": "Nuclear", "start": 41, "end": 48, "id": 9 }, { "text": "staining", "start": 49, "end": 57, "id": 10 }, { "text": "of", "start": 58, "end": 60, "id": 11 }, { "text": "Gli-1", "start": 61, "end": 66, "id": 12 }, { "text": "in", "start": 67, "end": 69, "id": 13 }, { "text": "(", "start": 70, "end": 71, "id": 14 }, { "text": "A", "start": 71, "end": 72, "id": 15 }, { "text": ")", "start": 72, "end": 73, "id": 16 }, { "text": "a", "start": 74, "end": 75, "id": 17 }, { "text": "trabecular", "start": 76, "end": 86, "id": 18 }, { "text": "pattern", "start": 87, "end": 94, "id": 19 }, { "text": "and", "start": 95, "end": 98, "id": 20 }, { "text": "(", "start": 99, "end": 100, "id": 21 }, { "text": "B", "start": 100, "end": 101, "id": 22 }, { "text": ")", "start": 101, "end": 102, "id": 23 }, { "text": "a", "start": 103, "end": 104, "id": 24 }, { "text": "pseudoacinar", "start": 105, "end": 117, "id": 25 }, { "text": "pattern", "start": 118, "end": 125, "id": 26 }, { "text": "in", "start": 126, "end": 128, "id": 27 }, { "text": "HCC", "start": 129, "end": 132, "id": 28 }, { "text": "tissues", "start": 133, "end": 140, "id": 29 }, { "text": ",", "start": 140, "end": 141, "id": 30 }, { "text": "in", "start": 142, "end": 144, "id": 31 }, { "text": "contrast", "start": 145, "end": 153, "id": 32 }, { "text": "to", "start": 154, "end": 156, "id": 33 }, { "text": "normal", "start": 157, "end": 163, "id": 34 }, { "text": "liver", "start": 164, "end": 169, "id": 35 }, { "text": "tissue", "start": 170, "end": 176, "id": 36 }, { "text": "(", "start": 177, "end": 178, "id": 37 }, { "text": "inset", "start": 178, "end": 183, "id": 38 }, { "text": "of", "start": 184, "end": 186, "id": 39 }, { "text": "A", "start": 187, "end": 188, "id": 40 }, { "text": ")", "start": 188, "end": 189, "id": 41 }, { "text": ".", "start": 189, "end": 190, "id": 42 }, { "text": "Strong", "start": 191, "end": 197, "id": 43 }, { "text": "and", "start": 198, "end": 201, "id": 44 }, { "text": "diffuse", "start": 202, "end": 209, "id": 45 }, { "text": "nuclear", "start": 210, "end": 217, "id": 46 }, { "text": "staining", "start": 218, "end": 226, "id": 47 }, { "text": "of", "start": 227, "end": 229, "id": 48 }, { "text": "Gli-2", "start": 230, "end": 235, "id": 49 }, { "text": "in", "start": 236, "end": 238, "id": 50 }, { "text": "(", "start": 239, "end": 240, "id": 51 }, { "text": "C", "start": 240, "end": 241, "id": 52 }, { "text": ")", "start": 241, "end": 242, "id": 53 }, { "text": "a", "start": 243, "end": 244, "id": 54 }, { "text": "trabecular", "start": 245, "end": 255, "id": 55 }, { "text": "pattern", "start": 256, "end": 263, "id": 56 }, { "text": "and", "start": 264, "end": 267, "id": 57 }, { "text": "(", "start": 268, "end": 269, "id": 58 }, { "text": "D", "start": 269, "end": 270, "id": 59 }, { "text": ")", "start": 270, "end": 271, "id": 60 }, { "text": "a", "start": 272, "end": 273, "id": 61 }, { "text": "pseudoacinar", "start": 274, "end": 286, "id": 62 }, { "text": "pattern", "start": 287, "end": 294, "id": 63 }, { "text": "in", "start": 295, "end": 297, "id": 64 }, { "text": "HCC", "start": 298, "end": 301, "id": 65 }, { "text": "tissues", "start": 302, "end": 309, "id": 66 }, { "text": ",", "start": 309, "end": 310, "id": 67 }, { "text": "in", "start": 311, "end": 313, "id": 68 }, { "text": "comparison", "start": 314, "end": 324, "id": 69 }, { "text": "to", "start": 325, "end": 327, "id": 70 }, { "text": "adjacent", "start": 328, "end": 336, "id": 71 }, { "text": "normal", "start": 337, "end": 343, "id": 72 }, { "text": "liver", "start": 344, "end": 349, "id": 73 }, { "text": "parenchyme", "start": 350, "end": 360, "id": 74 }, { "text": "(", "start": 361, "end": 362, "id": 75 }, { "text": "inset", "start": 362, "end": 367, "id": 76 }, { "text": "of", "start": 368, "end": 370, "id": 77 }, { "text": "C", "start": 371, "end": 372, "id": 78 }, { "text": ")", "start": 372, "end": 373, "id": 79 }, { "text": ".", "start": 373, "end": 374, "id": 80 }, { "text": "HCC", "start": 375, "end": 378, "id": 81 }, { "text": ",", "start": 378, "end": 379, "id": 82 }, { "text": "hepatocellular", "start": 380, "end": 394, "id": 83 }, { "text": "carcinoma", "start": 395, "end": 404, "id": 84 }, { "text": ".", "start": 404, "end": 405, "id": 85 }, { "text": "Magnification", "start": 406, "end": 419, "id": 86 }, { "text": "A", "start": 420, "end": 421, "id": 87 }, { "text": "-", "start": 421, "end": 422, "id": 88 }, { "text": "D", "start": 422, "end": 423, "id": 89 }, { "text": ",", "start": 423, "end": 424, "id": 90 }, { "text": "x20", "start": 425, "end": 428, "id": 91 }, { "text": ".", "start": 428, "end": 429, "id": 92 } ]
c238d364f2b4bb4bc02a538cf530efaba4fdf52c
Figure1
3-Figure1-1.png
Figure 1 Representative enhanced depth imaging OCT images of a patient who showed spontaneous resolution of CSC. Subfoveal choroidal thickness was 475 mm at first visit (a), and decreased to 410 mm after complete absorption of SRF (b). The arrows indicate the subfoveal choroidal thickness, the vertical distance from hyper-reflective line of the RPE Bruch's membrane to innermost hyperreflective line of chorioscleral interface.
926
196
{ "a": [ 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29 ], "b": [ 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "a9ee801a-86a9-4a16-aa9f-7c525e6285e2", "label": "a", "points": [ [ 19.3, 3.4 ], [ 19.3, 170.2 ], [ 450.8, 170.2 ], [ 450.8, 3.4 ] ], "color": "yellow" }, { "id": "e02f8f2c-73d9-4604-8606-2682b59aa07b", "label": "b", "points": [ [ 469.8, 7.8 ], [ 469.8, 164.3 ], [ 901.4, 164.3 ], [ 901.4, 7.8 ] ], "color": "cyan" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": "Representative", "start": 9, "end": 23, "id": 2 }, { "text": "enhanced", "start": 24, "end": 32, "id": 3 }, { "text": "depth", "start": 33, "end": 38, "id": 4 }, { "text": "imaging", "start": 39, "end": 46, "id": 5 }, { "text": "OCT", "start": 47, "end": 50, "id": 6 }, { "text": "images", "start": 51, "end": 57, "id": 7 }, { "text": "of", "start": 58, "end": 60, "id": 8 }, { "text": "a", "start": 61, "end": 62, "id": 9 }, { "text": "patient", "start": 63, "end": 70, "id": 10 }, { "text": "who", "start": 71, "end": 74, "id": 11 }, { "text": "showed", "start": 75, "end": 81, "id": 12 }, { "text": "spontaneous", "start": 82, "end": 93, "id": 13 }, { "text": "resolution", "start": 94, "end": 104, "id": 14 }, { "text": "of", "start": 105, "end": 107, "id": 15 }, { "text": "CSC", "start": 108, "end": 111, "id": 16 }, { "text": ".", "start": 111, "end": 112, "id": 17 }, { "text": "Subfoveal", "start": 113, "end": 122, "id": 18 }, { "text": "choroidal", "start": 123, "end": 132, "id": 19 }, { "text": "thickness", "start": 133, "end": 142, "id": 20 }, { "text": "was", "start": 143, "end": 146, "id": 21 }, { "text": "475", "start": 147, "end": 150, "id": 22 }, { "text": "mm", "start": 151, "end": 153, "id": 23 }, { "text": "at", "start": 154, "end": 156, "id": 24 }, { "text": "first", "start": 157, "end": 162, "id": 25 }, { "text": "visit", "start": 163, "end": 168, "id": 26 }, { "text": "(", "start": 169, "end": 170, "id": 27 }, { "text": "a", "start": 170, "end": 171, "id": 28 }, { "text": ")", "start": 171, "end": 172, "id": 29 }, { "text": ",", "start": 172, "end": 173, "id": 30 }, { "text": "and", "start": 174, "end": 177, "id": 31 }, { "text": "decreased", "start": 178, "end": 187, "id": 32 }, { "text": "to", "start": 188, "end": 190, "id": 33 }, { "text": "410", "start": 191, "end": 194, "id": 34 }, { "text": "mm", "start": 195, "end": 197, "id": 35 }, { "text": "after", "start": 198, "end": 203, "id": 36 }, { "text": "complete", "start": 204, "end": 212, "id": 37 }, { "text": "absorption", "start": 213, "end": 223, "id": 38 }, { "text": "of", "start": 224, "end": 226, "id": 39 }, { "text": "SRF", "start": 227, "end": 230, "id": 40 }, { "text": "(", "start": 231, "end": 232, "id": 41 }, { "text": "b", "start": 232, "end": 233, "id": 42 }, { "text": ")", "start": 233, "end": 234, "id": 43 }, { "text": ".", "start": 234, "end": 235, "id": 44 }, { "text": "The", "start": 236, "end": 239, "id": 45 }, { "text": "arrows", "start": 240, "end": 246, "id": 46 }, { "text": "indicate", "start": 247, "end": 255, "id": 47 }, { "text": "the", "start": 256, "end": 259, "id": 48 }, { "text": "subfoveal", "start": 260, "end": 269, "id": 49 }, { "text": "choroidal", "start": 270, "end": 279, "id": 50 }, { "text": "thickness", "start": 280, "end": 289, "id": 51 }, { "text": ",", "start": 289, "end": 290, "id": 52 }, { "text": "the", "start": 291, "end": 294, "id": 53 }, { "text": "vertical", "start": 295, "end": 303, "id": 54 }, { "text": "distance", "start": 304, "end": 312, "id": 55 }, { "text": "from", "start": 313, "end": 317, "id": 56 }, { "text": "hyper", "start": 318, "end": 323, "id": 57 }, { "text": "-", "start": 323, "end": 324, "id": 58 }, { "text": "reflective", "start": 324, "end": 334, "id": 59 }, { "text": "line", "start": 335, "end": 339, "id": 60 }, { "text": "of", "start": 340, "end": 342, "id": 61 }, { "text": "the", "start": 343, "end": 346, "id": 62 }, { "text": "RPE", "start": 347, "end": 350, "id": 63 }, { "text": "Bruch", "start": 351, "end": 356, "id": 64 }, { "text": "'s", "start": 356, "end": 358, "id": 65 }, { "text": "membrane", "start": 359, "end": 367, "id": 66 }, { "text": "to", "start": 368, "end": 370, "id": 67 }, { "text": "innermost", "start": 371, "end": 380, "id": 68 }, { "text": "hyperreflective", "start": 381, "end": 396, "id": 69 }, { "text": "line", "start": 397, "end": 401, "id": 70 }, { "text": "of", "start": 402, "end": 404, "id": 71 }, { "text": "chorioscleral", "start": 405, "end": 418, "id": 72 }, { "text": "interface", "start": 419, "end": 428, "id": 73 }, { "text": ".", "start": 428, "end": 429, "id": 74 } ]
46dae6f2acb6d69c578d95f361b7d667529ff54e
Figure3
4-Figure3-1.png
Fig. 3. High-resolution temporal bone computed tomography images of unilateral congenital aural atresia combined with microtia. Axial (A) and coronal (B) views showing the dilated vestibular morphology (arrows).
662
304
{ "a": [ 32, 33, 34, 35, 36, 37, 38, 39, 21, 22, 23, 24, 30, 31 ], "b": [ 32, 33, 34, 35, 36, 37, 38, 39, 26, 27, 28, 29, 30, 31 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "1ccb17d9-b919-46eb-9f95-8b623140722f", "label": "a", "points": [ [ 3.7, 5.1 ], [ 3.7, 301 ], [ 325.8, 301 ], [ 325.8, 5.1 ] ], "color": "yellow" }, { "id": "99e3c193-f6b1-4371-a4a2-49ff74638bcf", "label": "b", "points": [ [ 337.3, 1.9 ], [ 337.3, 302.1 ], [ 659.4, 302.1 ], [ 659.4, 1.9 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "3", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "High", "start": 8, "end": 12, "id": 4 }, { "text": "-", "start": 12, "end": 13, "id": 5 }, { "text": "resolution", "start": 13, "end": 23, "id": 6 }, { "text": "temporal", "start": 24, "end": 32, "id": 7 }, { "text": "bone", "start": 33, "end": 37, "id": 8 }, { "text": "computed", "start": 38, "end": 46, "id": 9 }, { "text": "tomography", "start": 47, "end": 57, "id": 10 }, { "text": "images", "start": 58, "end": 64, "id": 11 }, { "text": "of", "start": 65, "end": 67, "id": 12 }, { "text": "unilateral", "start": 68, "end": 78, "id": 13 }, { "text": "congenital", "start": 79, "end": 89, "id": 14 }, { "text": "aural", "start": 90, "end": 95, "id": 15 }, { "text": "atresia", "start": 96, "end": 103, "id": 16 }, { "text": "combined", "start": 104, "end": 112, "id": 17 }, { "text": "with", "start": 113, "end": 117, "id": 18 }, { "text": "microtia", "start": 118, "end": 126, "id": 19 }, { "text": ".", "start": 126, "end": 127, "id": 20 }, { "text": "Axial", "start": 128, "end": 133, "id": 21 }, { "text": "(", "start": 134, "end": 135, "id": 22 }, { "text": "A", "start": 135, "end": 136, "id": 23 }, { "text": ")", "start": 136, "end": 137, "id": 24 }, { "text": "and", "start": 138, "end": 141, "id": 25 }, { "text": "coronal", "start": 142, "end": 149, "id": 26 }, { "text": "(", "start": 150, "end": 151, "id": 27 }, { "text": "B", "start": 151, "end": 152, "id": 28 }, { "text": ")", "start": 152, "end": 153, "id": 29 }, { "text": "views", "start": 154, "end": 159, "id": 30 }, { "text": "showing", "start": 160, "end": 167, "id": 31 }, { "text": "the", "start": 168, "end": 171, "id": 32 }, { "text": "dilated", "start": 172, "end": 179, "id": 33 }, { "text": "vestibular", "start": 180, "end": 190, "id": 34 }, { "text": "morphology", "start": 191, "end": 201, "id": 35 }, { "text": "(", "start": 202, "end": 203, "id": 36 }, { "text": "arrows", "start": 203, "end": 209, "id": 37 }, { "text": ")", "start": 209, "end": 210, "id": 38 }, { "text": ".", "start": 210, "end": 211, "id": 39 } ]
efa0ca648909c4ca0b6c6ec8329769b90e0e6b6f
Figure2
2-Figure2-1.png
Figure 2. a-c. Coronal (a) and axial (b, c) contrast-enhanced CT scan revealing a heterogeneous soft tissue lesion with hyperdense areas involving the right nasal cavity and all ipsilateral sinuses; b, c. The axial cuts showing the lamina papyracea pushed by the tissue bulk that appeared to encroach the medial extraconal space (arrows)
1,458
548
{ "a": [ 7, 8, 9, 10, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40 ], "b": [ 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "00a06336-f2fa-4fe3-b424-c3395ac19427", "label": "a", "points": [ [ 5.8, 4.6 ], [ 5.8, 509.1 ], [ 478, 509.1 ], [ 478, 4.6 ] ], "color": "yellow" }, { "id": "1a64ee64-0733-4930-87b4-7cf45f7c4902", "label": "b", "points": [ [ 496.4, 4.6 ], [ 496.4, 499.8 ], [ 966.3, 499.8 ], [ 966.3, 4.6 ] ], "color": "cyan" }, { "id": "56fcfc49-44ed-4f2b-ac84-aaebc9b52a77", "label": "b", "points": [ [ 987, 0 ], [ 987, 504.5 ], [ 1452.3, 504.5 ], [ 1452.3, 0 ] ], "color": "magenta" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "2", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "a", "start": 10, "end": 11, "id": 3 }, { "text": "-", "start": 11, "end": 12, "id": 4 }, { "text": "c", "start": 12, "end": 13, "id": 5 }, { "text": ".", "start": 13, "end": 14, "id": 6 }, { "text": "Coronal", "start": 15, "end": 22, "id": 7 }, { "text": "(", "start": 23, "end": 24, "id": 8 }, { "text": "a", "start": 24, "end": 25, "id": 9 }, { "text": ")", "start": 25, "end": 26, "id": 10 }, { "text": "and", "start": 27, "end": 30, "id": 11 }, { "text": "axial", "start": 31, "end": 36, "id": 12 }, { "text": "(", "start": 37, "end": 38, "id": 13 }, { "text": "b", "start": 38, "end": 39, "id": 14 }, { "text": ",", "start": 39, "end": 40, "id": 15 }, { "text": "c", "start": 41, "end": 42, "id": 16 }, { "text": ")", "start": 42, "end": 43, "id": 17 }, { "text": "contrast", "start": 44, "end": 52, "id": 18 }, { "text": "-", "start": 52, "end": 53, "id": 19 }, { "text": "enhanced", "start": 53, "end": 61, "id": 20 }, { "text": "CT", "start": 62, "end": 64, "id": 21 }, { "text": "scan", "start": 65, "end": 69, "id": 22 }, { "text": "revealing", "start": 70, "end": 79, "id": 23 }, { "text": "a", "start": 80, "end": 81, "id": 24 }, { "text": "heterogeneous", "start": 82, "end": 95, "id": 25 }, { "text": "soft", "start": 96, "end": 100, "id": 26 }, { "text": "tissue", "start": 101, "end": 107, "id": 27 }, { "text": "lesion", "start": 108, "end": 114, "id": 28 }, { "text": "with", "start": 115, "end": 119, "id": 29 }, { "text": "hyperdense", "start": 120, "end": 130, "id": 30 }, { "text": "areas", "start": 131, "end": 136, "id": 31 }, { "text": "involving", "start": 137, "end": 146, "id": 32 }, { "text": "the", "start": 147, "end": 150, "id": 33 }, { "text": "right", "start": 151, "end": 156, "id": 34 }, { "text": "nasal", "start": 157, "end": 162, "id": 35 }, { "text": "cavity", "start": 163, "end": 169, "id": 36 }, { "text": "and", "start": 170, "end": 173, "id": 37 }, { "text": "all", "start": 174, "end": 177, "id": 38 }, { "text": "ipsilateral", "start": 178, "end": 189, "id": 39 }, { "text": "sinuses", "start": 190, "end": 197, "id": 40 }, { "text": ";", "start": 197, "end": 198, "id": 41 }, { "text": "b", "start": 199, "end": 200, "id": 42 }, { "text": ",", "start": 200, "end": 201, "id": 43 }, { "text": "c.", "start": 202, "end": 204, "id": 44 }, { "text": "The", "start": 205, "end": 208, "id": 45 }, { "text": "axial", "start": 209, "end": 214, "id": 46 }, { "text": "cuts", "start": 215, "end": 219, "id": 47 }, { "text": "showing", "start": 220, "end": 227, "id": 48 }, { "text": "the", "start": 228, "end": 231, "id": 49 }, { "text": "lamina", "start": 232, "end": 238, "id": 50 }, { "text": "papyracea", "start": 239, "end": 248, "id": 51 }, { "text": "pushed", "start": 249, "end": 255, "id": 52 }, { "text": "by", "start": 256, "end": 258, "id": 53 }, { "text": "the", "start": 259, "end": 262, "id": 54 }, { "text": "tissue", "start": 263, "end": 269, "id": 55 }, { "text": "bulk", "start": 270, "end": 274, "id": 56 }, { "text": "that", "start": 275, "end": 279, "id": 57 }, { "text": "appeared", "start": 280, "end": 288, "id": 58 }, { "text": "to", "start": 289, "end": 291, "id": 59 }, { "text": "encroach", "start": 292, "end": 300, "id": 60 }, { "text": "the", "start": 301, "end": 304, "id": 61 }, { "text": "medial", "start": 305, "end": 311, "id": 62 }, { "text": "extraconal", "start": 312, "end": 322, "id": 63 }, { "text": "space", "start": 323, "end": 328, "id": 64 }, { "text": "(", "start": 329, "end": 330, "id": 65 }, { "text": "arrows", "start": 330, "end": 336, "id": 66 }, { "text": ")", "start": 336, "end": 337, "id": 67 } ]
ed03aaa094e0b3c8fcb13f8ac4a746c5f6276e87
Figure2
5-Figure2-1.png
Fig. 2 X-ray and computer tomographic images of a 52-year-old immunocompromised patient after heart transplantation suffering from pulmonary aspergillosis (Aspergillus terreus). a Several lesions on both lungs on X-ray with two of the lesions b showing an air crescent sign (sagittal reconstruction). The lesion located in the lower lobe developed a ground-glass halo later on, and no pleural effusion is seen
552
1,310
{ "a": [ 29, 30, 31, 32, 33, 34, 35, 36, 37, 38 ], "b": [ 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "7337638c-69c4-4ece-9aee-77eda3748c1e", "label": "a", "points": [ [ 3.7, 4.3 ], [ 3.7, 626.3 ], [ 555.7, 626.3 ], [ 555.7, 4.3 ] ], "color": "yellow" }, { "id": "02a6d718-d07a-4719-8691-5273f6ab06cb", "label": "b", "points": [ [ 4.7, 642.7 ], [ 4.7, 1305.7 ], [ 547.7, 1305.7 ], [ 547.7, 642.7 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "2", "start": 5, "end": 6, "id": 2 }, { "text": "X", "start": 7, "end": 8, "id": 3 }, { "text": "-", "start": 8, "end": 9, "id": 4 }, { "text": "ray", "start": 9, "end": 12, "id": 5 }, { "text": "and", "start": 13, "end": 16, "id": 6 }, { "text": "computer", "start": 17, "end": 25, "id": 7 }, { "text": "tomographic", "start": 26, "end": 37, "id": 8 }, { "text": "images", "start": 38, "end": 44, "id": 9 }, { "text": "of", "start": 45, "end": 47, "id": 10 }, { "text": "a", "start": 48, "end": 49, "id": 11 }, { "text": "52-year", "start": 50, "end": 57, "id": 12 }, { "text": "-", "start": 57, "end": 58, "id": 13 }, { "text": "old", "start": 58, "end": 61, "id": 14 }, { "text": "immunocompromised", "start": 62, "end": 79, "id": 15 }, { "text": "patient", "start": 80, "end": 87, "id": 16 }, { "text": "after", "start": 88, "end": 93, "id": 17 }, { "text": "heart", "start": 94, "end": 99, "id": 18 }, { "text": "transplantation", "start": 100, "end": 115, "id": 19 }, { "text": "suffering", "start": 116, "end": 125, "id": 20 }, { "text": "from", "start": 126, "end": 130, "id": 21 }, { "text": "pulmonary", "start": 131, "end": 140, "id": 22 }, { "text": "aspergillosis", "start": 141, "end": 154, "id": 23 }, { "text": "(", "start": 155, "end": 156, "id": 24 }, { "text": "Aspergillus", "start": 156, "end": 167, "id": 25 }, { "text": "terreus", "start": 168, "end": 175, "id": 26 }, { "text": ")", "start": 175, "end": 176, "id": 27 }, { "text": ".", "start": 176, "end": 177, "id": 28 }, { "text": "a", "start": 178, "end": 179, "id": 29 }, { "text": "Several", "start": 180, "end": 187, "id": 30 }, { "text": "lesions", "start": 188, "end": 195, "id": 31 }, { "text": "on", "start": 196, "end": 198, "id": 32 }, { "text": "both", "start": 199, "end": 203, "id": 33 }, { "text": "lungs", "start": 204, "end": 209, "id": 34 }, { "text": "on", "start": 210, "end": 212, "id": 35 }, { "text": "X", "start": 213, "end": 214, "id": 36 }, { "text": "-", "start": 214, "end": 215, "id": 37 }, { "text": "ray", "start": 215, "end": 218, "id": 38 }, { "text": "with", "start": 219, "end": 223, "id": 39 }, { "text": "two", "start": 224, "end": 227, "id": 40 }, { "text": "of", "start": 228, "end": 230, "id": 41 }, { "text": "the", "start": 231, "end": 234, "id": 42 }, { "text": "lesions", "start": 235, "end": 242, "id": 43 }, { "text": "b", "start": 243, "end": 244, "id": 44 }, { "text": "showing", "start": 245, "end": 252, "id": 45 }, { "text": "an", "start": 253, "end": 255, "id": 46 }, { "text": "air", "start": 256, "end": 259, "id": 47 }, { "text": "crescent", "start": 260, "end": 268, "id": 48 }, { "text": "sign", "start": 269, "end": 273, "id": 49 }, { "text": "(", "start": 274, "end": 275, "id": 50 }, { "text": "sagittal", "start": 275, "end": 283, "id": 51 }, { "text": "reconstruction", "start": 284, "end": 298, "id": 52 }, { "text": ")", "start": 298, "end": 299, "id": 53 }, { "text": ".", "start": 299, "end": 300, "id": 54 }, { "text": "The", "start": 301, "end": 304, "id": 55 }, { "text": "lesion", "start": 305, "end": 311, "id": 56 }, { "text": "located", "start": 312, "end": 319, "id": 57 }, { "text": "in", "start": 320, "end": 322, "id": 58 }, { "text": "the", "start": 323, "end": 326, "id": 59 }, { "text": "lower", "start": 327, "end": 332, "id": 60 }, { "text": "lobe", "start": 333, "end": 337, "id": 61 }, { "text": "developed", "start": 338, "end": 347, "id": 62 }, { "text": "a", "start": 348, "end": 349, "id": 63 }, { "text": "ground", "start": 350, "end": 356, "id": 64 }, { "text": "-", "start": 356, "end": 357, "id": 65 }, { "text": "glass", "start": 357, "end": 362, "id": 66 }, { "text": "halo", "start": 363, "end": 367, "id": 67 }, { "text": "later", "start": 368, "end": 373, "id": 68 }, { "text": "on", "start": 374, "end": 376, "id": 69 }, { "text": ",", "start": 376, "end": 377, "id": 70 }, { "text": "and", "start": 378, "end": 381, "id": 71 }, { "text": "no", "start": 382, "end": 384, "id": 72 }, { "text": "pleural", "start": 385, "end": 392, "id": 73 }, { "text": "effusion", "start": 393, "end": 401, "id": 74 }, { "text": "is", "start": 402, "end": 404, "id": 75 }, { "text": "seen", "start": 405, "end": 409, "id": 76 } ]
7ed4606eeb9d69c305de537c0c56013cf4843af2
Figure1
3-Figure1-1.png
Figure 1: B-scan ultrasonography: (a) Eleven o'clock meridian acquired with a 10 MHz probe (Aviso, Quantel Médical) showing a typical retinal tear on B-scan ultrasonography. (b) Superior longitudinal scan acquired with a 20 MHz probe showing a typical retinal tear on B-scan ultrasonography. (c) Superior longitudinal scan acquired with a 20 MHz probe showing a retinal tear associated with retinal detachment. (d) Same pictures than in C with reversed grey scale for a better visualization of the retina and underlying tissue.
1,056
884
{ "a": [ 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36 ], "b": [ 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59 ], "c": [ 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80 ], "d": [ 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "10bdcf12-1f74-43d6-a1ea-312f71d2d53c", "label": "a", "points": [ [ 0.9, 1.4 ], [ 0.9, 380.1 ], [ 513, 380.1 ], [ 513, 1.4 ] ], "color": "yellow" }, { "id": "ac933595-5527-48ff-b7fc-add87f8d374d", "label": "b", "points": [ [ 553.1, 3.1 ], [ 553.1, 376.7 ], [ 1045.2, 376.7 ], [ 1045.2, 3.1 ] ], "color": "cyan" }, { "id": "59ac031f-0bfc-4cf8-9674-41bc7316fd22", "label": "c", "points": [ [ 4.2, 431.8 ], [ 4.2, 808.8 ], [ 521.4, 808.8 ], [ 521.4, 431.8 ] ], "color": "magenta" }, { "id": "f7185105-f9b9-4f7a-8366-43f9806f2fb7", "label": "d", "points": [ [ 551.4, 428.4 ], [ 551.4, 808.8 ], [ 1046.8, 808.8 ], [ 1046.8, 428.4 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": ":", "start": 8, "end": 9, "id": 2 }, { "text": "B", "start": 10, "end": 11, "id": 3 }, { "text": "-", "start": 11, "end": 12, "id": 4 }, { "text": "scan", "start": 12, "end": 16, "id": 5 }, { "text": "ultrasonography", "start": 17, "end": 32, "id": 6 }, { "text": ":", "start": 32, "end": 33, "id": 7 }, { "text": "(", "start": 34, "end": 35, "id": 8 }, { "text": "a", "start": 35, "end": 36, "id": 9 }, { "text": ")", "start": 36, "end": 37, "id": 10 }, { "text": "Eleven", "start": 38, "end": 44, "id": 11 }, { "text": "o'clock", "start": 45, "end": 52, "id": 12 }, { "text": "meridian", "start": 53, "end": 61, "id": 13 }, { "text": "acquired", "start": 62, "end": 70, "id": 14 }, { "text": "with", "start": 71, "end": 75, "id": 15 }, { "text": "a", "start": 76, "end": 77, "id": 16 }, { "text": "10", "start": 78, "end": 80, "id": 17 }, { "text": "MHz", "start": 81, "end": 84, "id": 18 }, { "text": "probe", "start": 85, "end": 90, "id": 19 }, { "text": "(", "start": 91, "end": 92, "id": 20 }, { "text": "Aviso", "start": 92, "end": 97, "id": 21 }, { "text": ",", "start": 97, "end": 98, "id": 22 }, { "text": "Quantel", "start": 99, "end": 106, "id": 23 }, { "text": "Médical", "start": 107, "end": 114, "id": 24 }, { "text": ")", "start": 114, "end": 115, "id": 25 }, { "text": "showing", "start": 116, "end": 123, "id": 26 }, { "text": "a", "start": 124, "end": 125, "id": 27 }, { "text": "typical", "start": 126, "end": 133, "id": 28 }, { "text": "retinal", "start": 134, "end": 141, "id": 29 }, { "text": "tear", "start": 142, "end": 146, "id": 30 }, { "text": "on", "start": 147, "end": 149, "id": 31 }, { "text": "B", "start": 150, "end": 151, "id": 32 }, { "text": "-", "start": 151, "end": 152, "id": 33 }, { "text": "scan", "start": 152, "end": 156, "id": 34 }, { "text": "ultrasonography", "start": 157, "end": 172, "id": 35 }, { "text": ".", "start": 172, "end": 173, "id": 36 }, { "text": "(", "start": 174, "end": 175, "id": 37 }, { "text": "b", "start": 175, "end": 176, "id": 38 }, { "text": ")", "start": 176, "end": 177, "id": 39 }, { "text": "Superior", "start": 178, "end": 186, "id": 40 }, { "text": "longitudinal", "start": 187, "end": 199, "id": 41 }, { "text": "scan", "start": 200, "end": 204, "id": 42 }, { "text": "acquired", "start": 205, "end": 213, "id": 43 }, { "text": "with", "start": 214, "end": 218, "id": 44 }, { "text": "a", "start": 219, "end": 220, "id": 45 }, { "text": "20", "start": 221, "end": 223, "id": 46 }, { "text": "MHz", "start": 224, "end": 227, "id": 47 }, { "text": "probe", "start": 228, "end": 233, "id": 48 }, { "text": "showing", "start": 234, "end": 241, "id": 49 }, { "text": "a", "start": 242, "end": 243, "id": 50 }, { "text": "typical", "start": 244, "end": 251, "id": 51 }, { "text": "retinal", "start": 252, "end": 259, "id": 52 }, { "text": "tear", "start": 260, "end": 264, "id": 53 }, { "text": "on", "start": 265, "end": 267, "id": 54 }, { "text": "B", "start": 268, "end": 269, "id": 55 }, { "text": "-", "start": 269, "end": 270, "id": 56 }, { "text": "scan", "start": 270, "end": 274, "id": 57 }, { "text": "ultrasonography", "start": 275, "end": 290, "id": 58 }, { "text": ".", "start": 290, "end": 291, "id": 59 }, { "text": "(", "start": 292, "end": 293, "id": 60 }, { "text": "c", "start": 293, "end": 294, "id": 61 }, { "text": ")", "start": 294, "end": 295, "id": 62 }, { "text": "Superior", "start": 296, "end": 304, "id": 63 }, { "text": "longitudinal", "start": 305, "end": 317, "id": 64 }, { "text": "scan", "start": 318, "end": 322, "id": 65 }, { "text": "acquired", "start": 323, "end": 331, "id": 66 }, { "text": "with", "start": 332, "end": 336, "id": 67 }, { "text": "a", "start": 337, "end": 338, "id": 68 }, { "text": "20", "start": 339, "end": 341, "id": 69 }, { "text": "MHz", "start": 342, "end": 345, "id": 70 }, { "text": "probe", "start": 346, "end": 351, "id": 71 }, { "text": "showing", "start": 352, "end": 359, "id": 72 }, { "text": "a", "start": 360, "end": 361, "id": 73 }, { "text": "retinal", "start": 362, "end": 369, "id": 74 }, { "text": "tear", "start": 370, "end": 374, "id": 75 }, { "text": "associated", "start": 375, "end": 385, "id": 76 }, { "text": "with", "start": 386, "end": 390, "id": 77 }, { "text": "retinal", "start": 391, "end": 398, "id": 78 }, { "text": "detachment", "start": 399, "end": 409, "id": 79 }, { "text": ".", "start": 409, "end": 410, "id": 80 }, { "text": "(", "start": 411, "end": 412, "id": 81 }, { "text": "d", "start": 412, "end": 413, "id": 82 }, { "text": ")", "start": 413, "end": 414, "id": 83 }, { "text": "Same", "start": 415, "end": 419, "id": 84 }, { "text": "pictures", "start": 420, "end": 428, "id": 85 }, { "text": "than", "start": 429, "end": 433, "id": 86 }, { "text": "in", "start": 434, "end": 436, "id": 87 }, { "text": "C", "start": 437, "end": 438, "id": 88 }, { "text": "with", "start": 439, "end": 443, "id": 89 }, { "text": "reversed", "start": 444, "end": 452, "id": 90 }, { "text": "grey", "start": 453, "end": 457, "id": 91 }, { "text": "scale", "start": 458, "end": 463, "id": 92 }, { "text": "for", "start": 464, "end": 467, "id": 93 }, { "text": "a", "start": 468, "end": 469, "id": 94 }, { "text": "better", "start": 470, "end": 476, "id": 95 }, { "text": "visualization", "start": 477, "end": 490, "id": 96 }, { "text": "of", "start": 491, "end": 493, "id": 97 }, { "text": "the", "start": 494, "end": 497, "id": 98 }, { "text": "retina", "start": 498, "end": 504, "id": 99 }, { "text": "and", "start": 505, "end": 508, "id": 100 }, { "text": "underlying", "start": 509, "end": 519, "id": 101 }, { "text": "tissue", "start": 520, "end": 526, "id": 102 }, { "text": ".", "start": 526, "end": 527, "id": 103 } ]
1f3d0722f9b4011a0022bc6de06fb3f7de89f890
Figure7
19-Figure7-1.png
Figure 7. This figure shows the hardware setup used for a low-cost MI-based EEG system e.g. in [134], [137] where (a) shows the 3D-printed prosthetic arm which was controlled and (b) shows the EEG headset used.
1,212
428
{ "a": [ 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42 ], "b": [ 44, 45, 46, 47, 48, 49, 50, 51 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "575751d6-9d02-4a90-9b71-7c6db3373e6f", "label": "a", "points": [ [ 2, 3.5 ], [ 2, 323.3 ], [ 607, 323.3 ], [ 607, 3.5 ] ], "color": "yellow" }, { "id": "1666667c-6e1d-425f-a004-58e85ac3d287", "label": "b", "points": [ [ 612.7, 7.3 ], [ 612.7, 313.7 ], [ 1202.4, 313.7 ], [ 1202.4, 7.3 ] ], "color": "cyan" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "7", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "This", "start": 10, "end": 14, "id": 3 }, { "text": "figure", "start": 15, "end": 21, "id": 4 }, { "text": "shows", "start": 22, "end": 27, "id": 5 }, { "text": "the", "start": 28, "end": 31, "id": 6 }, { "text": "hardware", "start": 32, "end": 40, "id": 7 }, { "text": "setup", "start": 41, "end": 46, "id": 8 }, { "text": "used", "start": 47, "end": 51, "id": 9 }, { "text": "for", "start": 52, "end": 55, "id": 10 }, { "text": "a", "start": 56, "end": 57, "id": 11 }, { "text": "low", "start": 58, "end": 61, "id": 12 }, { "text": "-", "start": 61, "end": 62, "id": 13 }, { "text": "cost", "start": 62, "end": 66, "id": 14 }, { "text": "MI", "start": 67, "end": 69, "id": 15 }, { "text": "-", "start": 69, "end": 70, "id": 16 }, { "text": "based", "start": 70, "end": 75, "id": 17 }, { "text": "EEG", "start": 76, "end": 79, "id": 18 }, { "text": "system", "start": 80, "end": 86, "id": 19 }, { "text": "e.g.", "start": 87, "end": 91, "id": 20 }, { "text": "in", "start": 92, "end": 94, "id": 21 }, { "text": "[", "start": 95, "end": 96, "id": 22 }, { "text": "134", "start": 96, "end": 99, "id": 23 }, { "text": "]", "start": 99, "end": 100, "id": 24 }, { "text": ",", "start": 100, "end": 101, "id": 25 }, { "text": "[", "start": 102, "end": 103, "id": 26 }, { "text": "137", "start": 103, "end": 106, "id": 27 }, { "text": "]", "start": 106, "end": 107, "id": 28 }, { "text": "where", "start": 108, "end": 113, "id": 29 }, { "text": "(", "start": 114, "end": 115, "id": 30 }, { "text": "a", "start": 115, "end": 116, "id": 31 }, { "text": ")", "start": 116, "end": 117, "id": 32 }, { "text": "shows", "start": 118, "end": 123, "id": 33 }, { "text": "the", "start": 124, "end": 127, "id": 34 }, { "text": "3D", "start": 128, "end": 130, "id": 35 }, { "text": "-", "start": 130, "end": 131, "id": 36 }, { "text": "printed", "start": 131, "end": 138, "id": 37 }, { "text": "prosthetic", "start": 139, "end": 149, "id": 38 }, { "text": "arm", "start": 150, "end": 153, "id": 39 }, { "text": "which", "start": 154, "end": 159, "id": 40 }, { "text": "was", "start": 160, "end": 163, "id": 41 }, { "text": "controlled", "start": 164, "end": 174, "id": 42 }, { "text": "and", "start": 175, "end": 178, "id": 43 }, { "text": "(", "start": 179, "end": 180, "id": 44 }, { "text": "b", "start": 180, "end": 181, "id": 45 }, { "text": ")", "start": 181, "end": 182, "id": 46 }, { "text": "shows", "start": 183, "end": 188, "id": 47 }, { "text": "the", "start": 189, "end": 192, "id": 48 }, { "text": "EEG", "start": 193, "end": 196, "id": 49 }, { "text": "headset", "start": 197, "end": 204, "id": 50 }, { "text": "used", "start": 205, "end": 209, "id": 51 }, { "text": ".", "start": 209, "end": 210, "id": 52 } ]
a01b549c7bf1e8808abf3e97faec20baef358c8e
Figure2
4-Figure2-1.png
Fig. 2 Radiological parameter measurement methods. a The coronal Cobb angle (CA) is measured from the superior end plate of the cephalad end vertebra and the inferior end plate of the caudal end vertebra on the coronal plane; the coronal vertical axis (CVA) is defined as the distance from a perpendicular line drawn from the superior end plate of S1 vertebral body to the C7 plumb line on the coronal plane. b The sagittal vertical axis (SVA) is defined as the distance from a perpendicular line drawn from the superior end plate of S1 vertebral body to the C7 plumb line on lateral radiographs; the thoracic kyphosis (TK) is measured from the upper end plate of T2 to the lower end plate of T12; the lumbar lordosis (LL) is measured from the upper end plate of T12 to the upper end plate of S1; the sacral slope (SS) is defined as the angle between the cranial sacral end plate and a horizontal line; the pelvic incidence (PI) is defined as the angle subtend by a line connecting the center of the femoral head to the center of the cephalad end plate of S1 and a perpendicular line from the upper end plate of S1; the pelvic tilt (PT) is measured as the angle between the vertical axis and the line through the midpoint of the sacral end plate to femoral heads axis
852
914
{ "a": [ 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78 ], "b": [ 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "35350b2b-7ffe-47ae-8e2a-9e038fac175c", "label": "a", "points": [ [ 31, 885.7 ], [ 31, 21.5 ], [ 429.4, 21.5 ], [ 429.4, 885.7 ] ], "color": "yellow" }, { "id": "d2487749-a81e-4969-b619-4a6c43e53f65", "label": "b", "points": [ [ 436.1, 25.6 ], [ 436.1, 872.2 ], [ 821, 872.2 ], [ 821, 25.6 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "2", "start": 5, "end": 6, "id": 2 }, { "text": "Radiological", "start": 7, "end": 19, "id": 3 }, { "text": "parameter", "start": 20, "end": 29, "id": 4 }, { "text": "measurement", "start": 30, "end": 41, "id": 5 }, { "text": "methods", "start": 42, "end": 49, "id": 6 }, { "text": ".", "start": 49, "end": 50, "id": 7 }, { "text": "a", "start": 51, "end": 52, "id": 8 }, { "text": "The", "start": 53, "end": 56, "id": 9 }, { "text": "coronal", "start": 57, "end": 64, "id": 10 }, { "text": "Cobb", "start": 65, "end": 69, "id": 11 }, { "text": "angle", "start": 70, "end": 75, "id": 12 }, { "text": "(", "start": 76, "end": 77, "id": 13 }, { "text": "CA", "start": 77, "end": 79, "id": 14 }, { "text": ")", "start": 79, "end": 80, "id": 15 }, { "text": "is", "start": 81, "end": 83, "id": 16 }, { "text": "measured", "start": 84, "end": 92, "id": 17 }, { "text": "from", "start": 93, "end": 97, "id": 18 }, { "text": "the", "start": 98, "end": 101, "id": 19 }, { "text": "superior", "start": 102, "end": 110, "id": 20 }, { "text": "end", "start": 111, "end": 114, "id": 21 }, { "text": "plate", "start": 115, "end": 120, "id": 22 }, { "text": "of", "start": 121, "end": 123, "id": 23 }, { "text": "the", "start": 124, "end": 127, "id": 24 }, { "text": "cephalad", "start": 128, "end": 136, "id": 25 }, { "text": "end", "start": 137, "end": 140, "id": 26 }, { "text": "vertebra", "start": 141, "end": 149, "id": 27 }, { "text": "and", "start": 150, "end": 153, "id": 28 }, { "text": "the", "start": 154, "end": 157, "id": 29 }, { "text": "inferior", "start": 158, "end": 166, "id": 30 }, { "text": "end", "start": 167, "end": 170, "id": 31 }, { "text": "plate", "start": 171, "end": 176, "id": 32 }, { "text": "of", "start": 177, "end": 179, "id": 33 }, { "text": "the", "start": 180, "end": 183, "id": 34 }, { "text": "caudal", "start": 184, "end": 190, "id": 35 }, { "text": "end", "start": 191, "end": 194, "id": 36 }, { "text": "vertebra", "start": 195, "end": 203, "id": 37 }, { "text": "on", "start": 204, "end": 206, "id": 38 }, { "text": "the", "start": 207, "end": 210, "id": 39 }, { "text": "coronal", "start": 211, "end": 218, "id": 40 }, { "text": "plane", "start": 219, "end": 224, "id": 41 }, { "text": ";", "start": 224, "end": 225, "id": 42 }, { "text": "the", "start": 226, "end": 229, "id": 43 }, { "text": "coronal", "start": 230, "end": 237, "id": 44 }, { "text": "vertical", "start": 238, "end": 246, "id": 45 }, { "text": "axis", "start": 247, "end": 251, "id": 46 }, { "text": "(", "start": 252, "end": 253, "id": 47 }, { "text": "CVA", "start": 253, "end": 256, "id": 48 }, { "text": ")", "start": 256, "end": 257, "id": 49 }, { "text": "is", "start": 258, "end": 260, "id": 50 }, { "text": "defined", "start": 261, "end": 268, "id": 51 }, { "text": "as", "start": 269, "end": 271, "id": 52 }, { "text": "the", "start": 272, "end": 275, "id": 53 }, { "text": "distance", "start": 276, "end": 284, "id": 54 }, { "text": "from", "start": 285, "end": 289, "id": 55 }, { "text": "a", "start": 290, "end": 291, "id": 56 }, { "text": "perpendicular", "start": 292, "end": 305, "id": 57 }, { "text": "line", "start": 306, "end": 310, "id": 58 }, { "text": "drawn", "start": 311, "end": 316, "id": 59 }, { "text": "from", "start": 317, "end": 321, "id": 60 }, { "text": "the", "start": 322, "end": 325, "id": 61 }, { "text": "superior", "start": 326, "end": 334, "id": 62 }, { "text": "end", "start": 335, "end": 338, "id": 63 }, { "text": "plate", "start": 339, "end": 344, "id": 64 }, { "text": "of", "start": 345, "end": 347, "id": 65 }, { "text": "S1", "start": 348, "end": 350, "id": 66 }, { "text": "vertebral", "start": 351, "end": 360, "id": 67 }, { "text": "body", "start": 361, "end": 365, "id": 68 }, { "text": "to", "start": 366, "end": 368, "id": 69 }, { "text": "the", "start": 369, "end": 372, "id": 70 }, { "text": "C7", "start": 373, "end": 375, "id": 71 }, { "text": "plumb", "start": 376, "end": 381, "id": 72 }, { "text": "line", "start": 382, "end": 386, "id": 73 }, { "text": "on", "start": 387, "end": 389, "id": 74 }, { "text": "the", "start": 390, "end": 393, "id": 75 }, { "text": "coronal", "start": 394, "end": 401, "id": 76 }, { "text": "plane", "start": 402, "end": 407, "id": 77 }, { "text": ".", "start": 407, "end": 408, "id": 78 }, { "text": "b", "start": 409, "end": 410, "id": 79 }, { "text": "The", "start": 411, "end": 414, "id": 80 }, { "text": "sagittal", "start": 415, "end": 423, "id": 81 }, { "text": "vertical", "start": 424, "end": 432, "id": 82 }, { "text": "axis", "start": 433, "end": 437, "id": 83 }, { "text": "(", "start": 438, "end": 439, "id": 84 }, { "text": "SVA", "start": 439, "end": 442, "id": 85 }, { "text": ")", "start": 442, "end": 443, "id": 86 }, { "text": "is", "start": 444, "end": 446, "id": 87 }, { "text": "defined", "start": 447, "end": 454, "id": 88 }, { "text": "as", "start": 455, "end": 457, "id": 89 }, { "text": "the", "start": 458, "end": 461, "id": 90 }, { "text": "distance", "start": 462, "end": 470, "id": 91 }, { "text": "from", "start": 471, "end": 475, "id": 92 }, { "text": "a", "start": 476, "end": 477, "id": 93 }, { "text": "perpendicular", "start": 478, "end": 491, "id": 94 }, { "text": "line", "start": 492, "end": 496, "id": 95 }, { "text": "drawn", "start": 497, "end": 502, "id": 96 }, { "text": "from", "start": 503, "end": 507, "id": 97 }, { "text": "the", "start": 508, "end": 511, "id": 98 }, { "text": "superior", "start": 512, "end": 520, "id": 99 }, { "text": "end", "start": 521, "end": 524, "id": 100 }, { "text": "plate", "start": 525, "end": 530, "id": 101 }, { "text": "of", "start": 531, "end": 533, "id": 102 }, { "text": "S1", "start": 534, "end": 536, "id": 103 }, { "text": "vertebral", "start": 537, "end": 546, "id": 104 }, { "text": "body", "start": 547, "end": 551, "id": 105 }, { "text": "to", "start": 552, "end": 554, "id": 106 }, { "text": "the", "start": 555, "end": 558, "id": 107 }, { "text": "C7", "start": 559, "end": 561, "id": 108 }, { "text": "plumb", "start": 562, "end": 567, "id": 109 }, { "text": "line", "start": 568, "end": 572, "id": 110 }, { "text": "on", "start": 573, "end": 575, "id": 111 }, { "text": "lateral", "start": 576, "end": 583, "id": 112 }, { "text": "radiographs", "start": 584, "end": 595, "id": 113 }, { "text": ";", "start": 595, "end": 596, "id": 114 }, { "text": "the", "start": 597, "end": 600, "id": 115 }, { "text": "thoracic", "start": 601, "end": 609, "id": 116 }, { "text": "kyphosis", "start": 610, "end": 618, "id": 117 }, { "text": "(", "start": 619, "end": 620, "id": 118 }, { "text": "TK", "start": 620, "end": 622, "id": 119 }, { "text": ")", "start": 622, "end": 623, "id": 120 }, { "text": "is", "start": 624, "end": 626, "id": 121 }, { "text": "measured", "start": 627, "end": 635, "id": 122 }, { "text": "from", "start": 636, "end": 640, "id": 123 }, { "text": "the", "start": 641, "end": 644, "id": 124 }, { "text": "upper", "start": 645, "end": 650, "id": 125 }, { "text": "end", "start": 651, "end": 654, "id": 126 }, { "text": "plate", "start": 655, "end": 660, "id": 127 }, { "text": "of", "start": 661, "end": 663, "id": 128 }, { "text": "T2", "start": 664, "end": 666, "id": 129 }, { "text": "to", "start": 667, "end": 669, "id": 130 }, { "text": "the", "start": 670, "end": 673, "id": 131 }, { "text": "lower", "start": 674, "end": 679, "id": 132 }, { "text": "end", "start": 680, "end": 683, "id": 133 }, { "text": "plate", "start": 684, "end": 689, "id": 134 }, { "text": "of", "start": 690, "end": 692, "id": 135 }, { "text": "T12", "start": 693, "end": 696, "id": 136 }, { "text": ";", "start": 696, "end": 697, "id": 137 }, { "text": "the", "start": 698, "end": 701, "id": 138 }, { "text": "lumbar", "start": 702, "end": 708, "id": 139 }, { "text": "lordosis", "start": 709, "end": 717, "id": 140 }, { "text": "(", "start": 718, "end": 719, "id": 141 }, { "text": "LL", "start": 719, "end": 721, "id": 142 }, { "text": ")", "start": 721, "end": 722, "id": 143 }, { "text": "is", "start": 723, "end": 725, "id": 144 }, { "text": "measured", "start": 726, "end": 734, "id": 145 }, { "text": "from", "start": 735, "end": 739, "id": 146 }, { "text": "the", "start": 740, "end": 743, "id": 147 }, { "text": "upper", "start": 744, "end": 749, "id": 148 }, { "text": "end", "start": 750, "end": 753, "id": 149 }, { "text": "plate", "start": 754, "end": 759, "id": 150 }, { "text": "of", "start": 760, "end": 762, "id": 151 }, { "text": "T12", "start": 763, "end": 766, "id": 152 }, { "text": "to", "start": 767, "end": 769, "id": 153 }, { "text": "the", "start": 770, "end": 773, "id": 154 }, { "text": "upper", "start": 774, "end": 779, "id": 155 }, { "text": "end", "start": 780, "end": 783, "id": 156 }, { "text": "plate", "start": 784, "end": 789, "id": 157 }, { "text": "of", "start": 790, "end": 792, "id": 158 }, { "text": "S1", "start": 793, "end": 795, "id": 159 }, { "text": ";", "start": 795, "end": 796, "id": 160 }, { "text": "the", "start": 797, "end": 800, "id": 161 }, { "text": "sacral", "start": 801, "end": 807, "id": 162 }, { "text": "slope", "start": 808, "end": 813, "id": 163 }, { "text": "(", "start": 814, "end": 815, "id": 164 }, { "text": "SS", "start": 815, "end": 817, "id": 165 }, { "text": ")", "start": 817, "end": 818, "id": 166 }, { "text": "is", "start": 819, "end": 821, "id": 167 }, { "text": "defined", "start": 822, "end": 829, "id": 168 }, { "text": "as", "start": 830, "end": 832, "id": 169 }, { "text": "the", "start": 833, "end": 836, "id": 170 }, { "text": "angle", "start": 837, "end": 842, "id": 171 }, { "text": "between", "start": 843, "end": 850, "id": 172 }, { "text": "the", "start": 851, "end": 854, "id": 173 }, { "text": "cranial", "start": 855, "end": 862, "id": 174 }, { "text": "sacral", "start": 863, "end": 869, "id": 175 }, { "text": "end", "start": 870, "end": 873, "id": 176 }, { "text": "plate", "start": 874, "end": 879, "id": 177 }, { "text": "and", "start": 880, "end": 883, "id": 178 }, { "text": "a", "start": 884, "end": 885, "id": 179 }, { "text": "horizontal", "start": 886, "end": 896, "id": 180 }, { "text": "line", "start": 897, "end": 901, "id": 181 }, { "text": ";", "start": 901, "end": 902, "id": 182 }, { "text": "the", "start": 903, "end": 906, "id": 183 }, { "text": "pelvic", "start": 907, "end": 913, "id": 184 }, { "text": "incidence", "start": 914, "end": 923, "id": 185 }, { "text": "(", "start": 924, "end": 925, "id": 186 }, { "text": "PI", "start": 925, "end": 927, "id": 187 }, { "text": ")", "start": 927, "end": 928, "id": 188 }, { "text": "is", "start": 929, "end": 931, "id": 189 }, { "text": "defined", "start": 932, "end": 939, "id": 190 }, { "text": "as", "start": 940, "end": 942, "id": 191 }, { "text": "the", "start": 943, "end": 946, "id": 192 }, { "text": "angle", "start": 947, "end": 952, "id": 193 }, { "text": "subtend", "start": 953, "end": 960, "id": 194 }, { "text": "by", "start": 961, "end": 963, "id": 195 }, { "text": "a", "start": 964, "end": 965, "id": 196 }, { "text": "line", "start": 966, "end": 970, "id": 197 }, { "text": "connecting", "start": 971, "end": 981, "id": 198 }, { "text": "the", "start": 982, "end": 985, "id": 199 }, { "text": "center", "start": 986, "end": 992, "id": 200 }, { "text": "of", "start": 993, "end": 995, "id": 201 }, { "text": "the", "start": 996, "end": 999, "id": 202 }, { "text": "femoral", "start": 1000, "end": 1007, "id": 203 }, { "text": "head", "start": 1008, "end": 1012, "id": 204 }, { "text": "to", "start": 1013, "end": 1015, "id": 205 }, { "text": "the", "start": 1016, "end": 1019, "id": 206 }, { "text": "center", "start": 1020, "end": 1026, "id": 207 }, { "text": "of", "start": 1027, "end": 1029, "id": 208 }, { "text": "the", "start": 1030, "end": 1033, "id": 209 }, { "text": "cephalad", "start": 1034, "end": 1042, "id": 210 }, { "text": "end", "start": 1043, "end": 1046, "id": 211 }, { "text": "plate", "start": 1047, "end": 1052, "id": 212 }, { "text": "of", "start": 1053, "end": 1055, "id": 213 }, { "text": "S1", "start": 1056, "end": 1058, "id": 214 }, { "text": "and", "start": 1059, "end": 1062, "id": 215 }, { "text": "a", "start": 1063, "end": 1064, "id": 216 }, { "text": "perpendicular", "start": 1065, "end": 1078, "id": 217 }, { "text": "line", "start": 1079, "end": 1083, "id": 218 }, { "text": "from", "start": 1084, "end": 1088, "id": 219 }, { "text": "the", "start": 1089, "end": 1092, "id": 220 }, { "text": "upper", "start": 1093, "end": 1098, "id": 221 }, { "text": "end", "start": 1099, "end": 1102, "id": 222 }, { "text": "plate", "start": 1103, "end": 1108, "id": 223 }, { "text": "of", "start": 1109, "end": 1111, "id": 224 }, { "text": "S1", "start": 1112, "end": 1114, "id": 225 }, { "text": ";", "start": 1114, "end": 1115, "id": 226 }, { "text": "the", "start": 1116, "end": 1119, "id": 227 }, { "text": "pelvic", "start": 1120, "end": 1126, "id": 228 }, { "text": "tilt", "start": 1127, "end": 1131, "id": 229 }, { "text": "(", "start": 1132, "end": 1133, "id": 230 }, { "text": "PT", "start": 1133, "end": 1135, "id": 231 }, { "text": ")", "start": 1135, "end": 1136, "id": 232 }, { "text": "is", "start": 1137, "end": 1139, "id": 233 }, { "text": "measured", "start": 1140, "end": 1148, "id": 234 }, { "text": "as", "start": 1149, "end": 1151, "id": 235 }, { "text": "the", "start": 1152, "end": 1155, "id": 236 }, { "text": "angle", "start": 1156, "end": 1161, "id": 237 }, { "text": "between", "start": 1162, "end": 1169, "id": 238 }, { "text": "the", "start": 1170, "end": 1173, "id": 239 }, { "text": "vertical", "start": 1174, "end": 1182, "id": 240 }, { "text": "axis", "start": 1183, "end": 1187, "id": 241 }, { "text": "and", "start": 1188, "end": 1191, "id": 242 }, { "text": "the", "start": 1192, "end": 1195, "id": 243 }, { "text": "line", "start": 1196, "end": 1200, "id": 244 }, { "text": "through", "start": 1201, "end": 1208, "id": 245 }, { "text": "the", "start": 1209, "end": 1212, "id": 246 }, { "text": "midpoint", "start": 1213, "end": 1221, "id": 247 }, { "text": "of", "start": 1222, "end": 1224, "id": 248 }, { "text": "the", "start": 1225, "end": 1228, "id": 249 }, { "text": "sacral", "start": 1229, "end": 1235, "id": 250 }, { "text": "end", "start": 1236, "end": 1239, "id": 251 }, { "text": "plate", "start": 1240, "end": 1245, "id": 252 }, { "text": "to", "start": 1246, "end": 1248, "id": 253 }, { "text": "femoral", "start": 1249, "end": 1256, "id": 254 }, { "text": "heads", "start": 1257, "end": 1262, "id": 255 }, { "text": "axis", "start": 1263, "end": 1267, "id": 256 } ]
acb6bb938b36e366074e9e372e29aacb626806c6
Figure1
6-Figure1-1.png
Fig 1. A typical example of the BRB maneuver attempted in the case of a 34 year-old woman with a fibroid in a forward-bent uterus. A. A sagittal survey scan showed that the bowel loops (arrow) were interposed between the uterus and the anterior abdominal wall. F and U indicate the target fibroid and the urinary bladder respectively. Dotted lines delineate the margins of each structure, and transparent orange triangles represent the planned HIFU beam path. B. After filling with 500 mL of saline, the urinary bladder (U) was distended and displaced the uterus cranially. However, the interposed bowel loops (arrow) were still in the anticipated sonication path. F indicates the target fibroid. Dotted lines delineate the margins of each structure. C. The rectum (R) was filled with 150 mL of gel. The distended rectum pushed the uterine cervix and the uterus antero-cranially, which displaced the bowel loops (arrow) out of the anticipated sonication path. F indicates the target fibroid and U indicates the urinary bladder. Dotted lines delineate the margins of each structure. D. The uterus descended after drainage of the urinary bladder (U), although the previouslyinterposed bowel loops (arrow) remained out of the anticipated sonication path. After a successful BRB maneuver, MR-HIFU ablation was performed. F indicates the target fibroid and R indicates the rectum. Dotted lines delineate the margins of each structure.
882
1,042
{ "a": [ 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87 ], "b": [ 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142 ], "c": [ 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206 ], "d": [ 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "4dbe3052-267e-4280-8688-e03d322f441f", "label": "a", "points": [ [ 3.5, 3.7 ], [ 3.5, 505.3 ], [ 422.9, 505.3 ], [ 422.9, 3.7 ] ], "color": "yellow" }, { "id": "913ac5d7-012a-46f9-874d-ee1ea637c649", "label": "b", "points": [ [ 429.9, 2.3 ], [ 429.9, 505.3 ], [ 846.5, 505.3 ], [ 846.5, 2.3 ] ], "color": "cyan" }, { "id": "f5ae4dcb-cb2f-421f-be4c-74b9cf8c4710", "label": "c", "points": [ [ 3.5, 510.9 ], [ 3.5, 1002.8 ], [ 424.3, 1002.8 ], [ 424.3, 510.9 ] ], "color": "magenta" }, { "id": "0db16f55-e734-405b-8448-492d765975c1", "label": "d", "points": [ [ 429.9, 509.5 ], [ 429.9, 1008.4 ], [ 847.9, 1008.4 ], [ 847.9, 509.5 ] ], "color": "springgreen" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": "1", "start": 4, "end": 5, "id": 1 }, { "text": ".", "start": 5, "end": 6, "id": 2 }, { "text": "A", "start": 7, "end": 8, "id": 3 }, { "text": "typical", "start": 9, "end": 16, "id": 4 }, { "text": "example", "start": 17, "end": 24, "id": 5 }, { "text": "of", "start": 25, "end": 27, "id": 6 }, { "text": "the", "start": 28, "end": 31, "id": 7 }, { "text": "BRB", "start": 32, "end": 35, "id": 8 }, { "text": "maneuver", "start": 36, "end": 44, "id": 9 }, { "text": "attempted", "start": 45, "end": 54, "id": 10 }, { "text": "in", "start": 55, "end": 57, "id": 11 }, { "text": "the", "start": 58, "end": 61, "id": 12 }, { "text": "case", "start": 62, "end": 66, "id": 13 }, { "text": "of", "start": 67, "end": 69, "id": 14 }, { "text": "a", "start": 70, "end": 71, "id": 15 }, { "text": "34", "start": 72, "end": 74, "id": 16 }, { "text": "year", "start": 75, "end": 79, "id": 17 }, { "text": "-", "start": 79, "end": 80, "id": 18 }, { "text": "old", "start": 80, "end": 83, "id": 19 }, { "text": "woman", "start": 84, "end": 89, "id": 20 }, { "text": "with", "start": 90, "end": 94, "id": 21 }, { "text": "a", "start": 95, "end": 96, "id": 22 }, { "text": "fibroid", "start": 97, "end": 104, "id": 23 }, { "text": "in", "start": 105, "end": 107, "id": 24 }, { "text": "a", "start": 108, "end": 109, "id": 25 }, { "text": "forward", "start": 110, "end": 117, "id": 26 }, { "text": "-", "start": 117, "end": 118, "id": 27 }, { "text": "bent", "start": 118, "end": 122, "id": 28 }, { "text": "uterus", "start": 123, "end": 129, "id": 29 }, { "text": ".", "start": 129, "end": 130, "id": 30 }, { "text": "A.", "start": 131, "end": 133, "id": 31 }, { "text": "A", "start": 134, "end": 135, "id": 32 }, { "text": "sagittal", "start": 136, "end": 144, "id": 33 }, { "text": "survey", "start": 145, "end": 151, "id": 34 }, { "text": "scan", "start": 152, "end": 156, "id": 35 }, { "text": "showed", "start": 157, "end": 163, "id": 36 }, { "text": "that", "start": 164, "end": 168, "id": 37 }, { "text": "the", "start": 169, "end": 172, "id": 38 }, { "text": "bowel", "start": 173, "end": 178, "id": 39 }, { "text": "loops", "start": 179, "end": 184, "id": 40 }, { "text": "(", "start": 185, "end": 186, "id": 41 }, { "text": "arrow", "start": 186, "end": 191, "id": 42 }, { "text": ")", "start": 191, "end": 192, "id": 43 }, { "text": "were", "start": 193, "end": 197, "id": 44 }, { "text": "interposed", "start": 198, "end": 208, "id": 45 }, { "text": "between", "start": 209, "end": 216, "id": 46 }, { "text": "the", "start": 217, "end": 220, "id": 47 }, { "text": "uterus", "start": 221, "end": 227, "id": 48 }, { "text": "and", "start": 228, "end": 231, "id": 49 }, { "text": "the", "start": 232, "end": 235, "id": 50 }, { "text": "anterior", "start": 236, "end": 244, "id": 51 }, { "text": "abdominal", "start": 245, "end": 254, "id": 52 }, { "text": "wall", "start": 255, "end": 259, "id": 53 }, { "text": ".", "start": 259, "end": 260, "id": 54 }, { "text": "F", "start": 261, "end": 262, "id": 55 }, { "text": "and", "start": 263, "end": 266, "id": 56 }, { "text": "U", "start": 267, "end": 268, "id": 57 }, { "text": "indicate", "start": 269, "end": 277, "id": 58 }, { "text": "the", "start": 278, "end": 281, "id": 59 }, { "text": "target", "start": 282, "end": 288, "id": 60 }, { "text": "fibroid", "start": 289, "end": 296, "id": 61 }, { "text": "and", "start": 297, "end": 300, "id": 62 }, { "text": "the", "start": 301, "end": 304, "id": 63 }, { "text": "urinary", "start": 305, "end": 312, "id": 64 }, { "text": "bladder", "start": 313, "end": 320, "id": 65 }, { "text": "respectively", "start": 321, "end": 333, "id": 66 }, { "text": ".", "start": 333, "end": 334, "id": 67 }, { "text": "Dotted", "start": 335, "end": 341, "id": 68 }, { "text": "lines", "start": 342, "end": 347, "id": 69 }, { "text": "delineate", "start": 348, "end": 357, "id": 70 }, { "text": "the", "start": 358, "end": 361, "id": 71 }, { "text": "margins", "start": 362, "end": 369, "id": 72 }, { "text": "of", "start": 370, "end": 372, "id": 73 }, { "text": "each", "start": 373, "end": 377, "id": 74 }, { "text": "structure", "start": 378, "end": 387, "id": 75 }, { "text": ",", "start": 387, "end": 388, "id": 76 }, { "text": "and", "start": 389, "end": 392, "id": 77 }, { "text": "transparent", "start": 393, "end": 404, "id": 78 }, { "text": "orange", "start": 405, "end": 411, "id": 79 }, { "text": "triangles", "start": 412, "end": 421, "id": 80 }, { "text": "represent", "start": 422, "end": 431, "id": 81 }, { "text": "the", "start": 432, "end": 435, "id": 82 }, { "text": "planned", "start": 436, "end": 443, "id": 83 }, { "text": "HIFU", "start": 444, "end": 448, "id": 84 }, { "text": "beam", "start": 449, "end": 453, "id": 85 }, { "text": "path", "start": 454, "end": 458, "id": 86 }, { "text": ".", "start": 458, "end": 459, "id": 87 }, { "text": "B.", "start": 460, "end": 462, "id": 88 }, { "text": "After", "start": 463, "end": 468, "id": 89 }, { "text": "filling", "start": 469, "end": 476, "id": 90 }, { "text": "with", "start": 477, "end": 481, "id": 91 }, { "text": "500", "start": 482, "end": 485, "id": 92 }, { "text": "mL", "start": 486, "end": 488, "id": 93 }, { "text": "of", "start": 489, "end": 491, "id": 94 }, { "text": "saline", "start": 492, "end": 498, "id": 95 }, { "text": ",", "start": 498, "end": 499, "id": 96 }, { "text": "the", "start": 500, "end": 503, "id": 97 }, { "text": "urinary", "start": 504, "end": 511, "id": 98 }, { "text": "bladder", "start": 512, "end": 519, "id": 99 }, { "text": "(", "start": 520, "end": 521, "id": 100 }, { "text": "U", "start": 521, "end": 522, "id": 101 }, { "text": ")", "start": 522, "end": 523, "id": 102 }, { "text": "was", "start": 524, "end": 527, "id": 103 }, { "text": "distended", "start": 528, "end": 537, "id": 104 }, { "text": "and", "start": 538, "end": 541, "id": 105 }, { "text": "displaced", "start": 542, "end": 551, "id": 106 }, { "text": "the", "start": 552, "end": 555, "id": 107 }, { "text": "uterus", "start": 556, "end": 562, "id": 108 }, { "text": "cranially", "start": 563, "end": 572, "id": 109 }, { "text": ".", "start": 572, "end": 573, "id": 110 }, { "text": "However", "start": 574, "end": 581, "id": 111 }, { "text": ",", "start": 581, "end": 582, "id": 112 }, { "text": "the", "start": 583, "end": 586, "id": 113 }, { "text": "interposed", "start": 587, "end": 597, "id": 114 }, { "text": "bowel", "start": 598, "end": 603, "id": 115 }, { "text": "loops", "start": 604, "end": 609, "id": 116 }, { "text": "(", "start": 610, "end": 611, "id": 117 }, { "text": "arrow", "start": 611, "end": 616, "id": 118 }, { "text": ")", "start": 616, "end": 617, "id": 119 }, { "text": "were", "start": 618, "end": 622, "id": 120 }, { "text": "still", "start": 623, "end": 628, "id": 121 }, { "text": "in", "start": 629, "end": 631, "id": 122 }, { "text": "the", "start": 632, "end": 635, "id": 123 }, { "text": "anticipated", "start": 636, "end": 647, "id": 124 }, { "text": "sonication", "start": 648, "end": 658, "id": 125 }, { "text": "path", "start": 659, "end": 663, "id": 126 }, { "text": ".", "start": 663, "end": 664, "id": 127 }, { "text": "F", "start": 665, "end": 666, "id": 128 }, { "text": "indicates", "start": 667, "end": 676, "id": 129 }, { "text": "the", "start": 677, "end": 680, "id": 130 }, { "text": "target", "start": 681, "end": 687, "id": 131 }, { "text": "fibroid", "start": 688, "end": 695, "id": 132 }, { "text": ".", "start": 695, "end": 696, "id": 133 }, { "text": "Dotted", "start": 697, "end": 703, "id": 134 }, { "text": "lines", "start": 704, "end": 709, "id": 135 }, { "text": "delineate", "start": 710, "end": 719, "id": 136 }, { "text": "the", "start": 720, "end": 723, "id": 137 }, { "text": "margins", "start": 724, "end": 731, "id": 138 }, { "text": "of", "start": 732, "end": 734, "id": 139 }, { "text": "each", "start": 735, "end": 739, "id": 140 }, { "text": "structure", "start": 740, "end": 749, "id": 141 }, { "text": ".", "start": 749, "end": 750, "id": 142 }, { "text": "C.", "start": 751, "end": 753, "id": 143 }, { "text": "The", "start": 754, "end": 757, "id": 144 }, { "text": "rectum", "start": 758, "end": 764, "id": 145 }, { "text": "(", "start": 765, "end": 766, "id": 146 }, { "text": "R", "start": 766, "end": 767, "id": 147 }, { "text": ")", "start": 767, "end": 768, "id": 148 }, { "text": "was", "start": 769, "end": 772, "id": 149 }, { "text": "filled", "start": 773, "end": 779, "id": 150 }, { "text": "with", "start": 780, "end": 784, "id": 151 }, { "text": "150", "start": 785, "end": 788, "id": 152 }, { "text": "mL", "start": 789, "end": 791, "id": 153 }, { "text": "of", "start": 792, "end": 794, "id": 154 }, { "text": "gel", "start": 795, "end": 798, "id": 155 }, { "text": ".", "start": 798, "end": 799, "id": 156 }, { "text": "The", "start": 800, "end": 803, "id": 157 }, { "text": "distended", "start": 804, "end": 813, "id": 158 }, { "text": "rectum", "start": 814, "end": 820, "id": 159 }, { "text": "pushed", "start": 821, "end": 827, "id": 160 }, { "text": "the", "start": 828, "end": 831, "id": 161 }, { "text": "uterine", "start": 832, "end": 839, "id": 162 }, { "text": "cervix", "start": 840, "end": 846, "id": 163 }, { "text": "and", "start": 847, "end": 850, "id": 164 }, { "text": "the", "start": 851, "end": 854, "id": 165 }, { "text": "uterus", "start": 855, "end": 861, "id": 166 }, { "text": "antero", "start": 862, "end": 868, "id": 167 }, { "text": "-", "start": 868, "end": 869, "id": 168 }, { "text": "cranially", "start": 869, "end": 878, "id": 169 }, { "text": ",", "start": 878, "end": 879, "id": 170 }, { "text": "which", "start": 880, "end": 885, "id": 171 }, { "text": "displaced", "start": 886, "end": 895, "id": 172 }, { "text": "the", "start": 896, "end": 899, "id": 173 }, { "text": "bowel", "start": 900, "end": 905, "id": 174 }, { "text": "loops", "start": 906, "end": 911, "id": 175 }, { "text": "(", "start": 912, "end": 913, "id": 176 }, { "text": "arrow", "start": 913, "end": 918, "id": 177 }, { "text": ")", "start": 918, "end": 919, "id": 178 }, { "text": "out", "start": 920, "end": 923, "id": 179 }, { "text": "of", "start": 924, "end": 926, "id": 180 }, { "text": "the", "start": 927, "end": 930, "id": 181 }, { "text": "anticipated", "start": 931, "end": 942, "id": 182 }, { "text": "sonication", "start": 943, "end": 953, "id": 183 }, { "text": "path", "start": 954, "end": 958, "id": 184 }, { "text": ".", "start": 958, "end": 959, "id": 185 }, { "text": "F", "start": 960, "end": 961, "id": 186 }, { "text": "indicates", "start": 962, "end": 971, "id": 187 }, { "text": "the", "start": 972, "end": 975, "id": 188 }, { "text": "target", "start": 976, "end": 982, "id": 189 }, { "text": "fibroid", "start": 983, "end": 990, "id": 190 }, { "text": "and", "start": 991, "end": 994, "id": 191 }, { "text": "U", "start": 995, "end": 996, "id": 192 }, { "text": "indicates", "start": 997, "end": 1006, "id": 193 }, { "text": "the", "start": 1007, "end": 1010, "id": 194 }, { "text": "urinary", "start": 1011, "end": 1018, "id": 195 }, { "text": "bladder", "start": 1019, "end": 1026, "id": 196 }, { "text": ".", "start": 1026, "end": 1027, "id": 197 }, { "text": "Dotted", "start": 1028, "end": 1034, "id": 198 }, { "text": "lines", "start": 1035, "end": 1040, "id": 199 }, { "text": "delineate", "start": 1041, "end": 1050, "id": 200 }, { "text": "the", "start": 1051, "end": 1054, "id": 201 }, { "text": "margins", "start": 1055, "end": 1062, "id": 202 }, { "text": "of", "start": 1063, "end": 1065, "id": 203 }, { "text": "each", "start": 1066, "end": 1070, "id": 204 }, { "text": "structure", "start": 1071, "end": 1080, "id": 205 }, { "text": ".", "start": 1080, "end": 1081, "id": 206 }, { "text": "D.", "start": 1082, "end": 1084, "id": 207 }, { "text": "The", "start": 1085, "end": 1088, "id": 208 }, { "text": "uterus", "start": 1089, "end": 1095, "id": 209 }, { "text": "descended", "start": 1096, "end": 1105, "id": 210 }, { "text": "after", "start": 1106, "end": 1111, "id": 211 }, { "text": "drainage", "start": 1112, "end": 1120, "id": 212 }, { "text": "of", "start": 1121, "end": 1123, "id": 213 }, { "text": "the", "start": 1124, "end": 1127, "id": 214 }, { "text": "urinary", "start": 1128, "end": 1135, "id": 215 }, { "text": "bladder", "start": 1136, "end": 1143, "id": 216 }, { "text": "(", "start": 1144, "end": 1145, "id": 217 }, { "text": "U", "start": 1145, "end": 1146, "id": 218 }, { "text": ")", "start": 1146, "end": 1147, "id": 219 }, { "text": ",", "start": 1147, "end": 1148, "id": 220 }, { "text": "although", "start": 1149, "end": 1157, "id": 221 }, { "text": "the", "start": 1158, "end": 1161, "id": 222 }, { "text": "previouslyinterposed", "start": 1162, "end": 1182, "id": 223 }, { "text": "bowel", "start": 1183, "end": 1188, "id": 224 }, { "text": "loops", "start": 1189, "end": 1194, "id": 225 }, { "text": "(", "start": 1195, "end": 1196, "id": 226 }, { "text": "arrow", "start": 1196, "end": 1201, "id": 227 }, { "text": ")", "start": 1201, "end": 1202, "id": 228 }, { "text": "remained", "start": 1203, "end": 1211, "id": 229 }, { "text": "out", "start": 1212, "end": 1215, "id": 230 }, { "text": "of", "start": 1216, "end": 1218, "id": 231 }, { "text": "the", "start": 1219, "end": 1222, "id": 232 }, { "text": "anticipated", "start": 1223, "end": 1234, "id": 233 }, { "text": "sonication", "start": 1235, "end": 1245, "id": 234 }, { "text": "path", "start": 1246, "end": 1250, "id": 235 }, { "text": ".", "start": 1250, "end": 1251, "id": 236 }, { "text": "After", "start": 1252, "end": 1257, "id": 237 }, { "text": "a", "start": 1258, "end": 1259, "id": 238 }, { "text": "successful", "start": 1260, "end": 1270, "id": 239 }, { "text": "BRB", "start": 1271, "end": 1274, "id": 240 }, { "text": "maneuver", "start": 1275, "end": 1283, "id": 241 }, { "text": ",", "start": 1283, "end": 1284, "id": 242 }, { "text": "MR", "start": 1285, "end": 1287, "id": 243 }, { "text": "-", "start": 1287, "end": 1288, "id": 244 }, { "text": "HIFU", "start": 1288, "end": 1292, "id": 245 }, { "text": "ablation", "start": 1293, "end": 1301, "id": 246 }, { "text": "was", "start": 1302, "end": 1305, "id": 247 }, { "text": "performed", "start": 1306, "end": 1315, "id": 248 }, { "text": ".", "start": 1315, "end": 1316, "id": 249 }, { "text": "F", "start": 1317, "end": 1318, "id": 250 }, { "text": "indicates", "start": 1319, "end": 1328, "id": 251 }, { "text": "the", "start": 1329, "end": 1332, "id": 252 }, { "text": "target", "start": 1333, "end": 1339, "id": 253 }, { "text": "fibroid", "start": 1340, "end": 1347, "id": 254 }, { "text": "and", "start": 1348, "end": 1351, "id": 255 }, { "text": "R", "start": 1352, "end": 1353, "id": 256 }, { "text": "indicates", "start": 1354, "end": 1363, "id": 257 }, { "text": "the", "start": 1364, "end": 1367, "id": 258 }, { "text": "rectum", "start": 1368, "end": 1374, "id": 259 }, { "text": ".", "start": 1374, "end": 1375, "id": 260 }, { "text": "Dotted", "start": 1376, "end": 1382, "id": 261 }, { "text": "lines", "start": 1383, "end": 1388, "id": 262 }, { "text": "delineate", "start": 1389, "end": 1398, "id": 263 }, { "text": "the", "start": 1399, "end": 1402, "id": 264 }, { "text": "margins", "start": 1403, "end": 1410, "id": 265 }, { "text": "of", "start": 1411, "end": 1413, "id": 266 }, { "text": "each", "start": 1414, "end": 1418, "id": 267 }, { "text": "structure", "start": 1419, "end": 1428, "id": 268 }, { "text": ".", "start": 1428, "end": 1429, "id": 269 } ]
3a94e95c9f3ffa9fe9a8ef7034edb06d49f37d61
Figure14
12-Figure14-1.png
Figure 14. Bile duct stricture due to intrahepatic duct stones 3 years after left lobectomy in a 50-year-old man who presented with jaundice. The patient's serum bilirubin level was elevated (12.43 mg/dL [212.6 µmol/L]). (a) Coronal T2-weighted RARE image shows a stricture (arrow) and dilatation of the proximal intrahepatic ducts. (b) Gd-EOB-DTPA-enhanced T1-weighted 3D GRE image obtained 60 minutes after injection shows no excretion of contrast material into the right main hepatic duct (arrow). (c) Image from direct cholangiography shows the high-grade stricture (arrow) of the right main hepatic duct.
670
1,088
{ "a": [ 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68 ], "b": [ 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103 ], "c": [ 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "3760349c-0aba-4248-98ca-5b1f4e0ea014", "label": "a", "points": [ [ 5.5, 4.6 ], [ 5.5, 513.7 ], [ 98.6, 513.7 ], [ 98.6, 4.6 ] ], "color": "yellow" }, { "id": "1cf5fd39-27ce-4733-b288-18e3f95a103d", "label": "b", "points": [ [ 119.8, 5.6 ], [ 119.8, 509.5 ], [ 669.1, 509.5 ], [ 669.1, 5.6 ] ], "color": "cyan" }, { "id": "9fc01ccb-de26-4f8c-a89d-c2474508bce0", "label": "c", "points": [ [ 107.1, 561.3 ], [ 107.1, 1060.9 ], [ 666, 1060.9 ], [ 666, 561.3 ] ], "color": "magenta" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "14", "start": 7, "end": 9, "id": 1 }, { "text": ".", "start": 9, "end": 10, "id": 2 }, { "text": "Bile", "start": 11, "end": 15, "id": 3 }, { "text": "duct", "start": 16, "end": 20, "id": 4 }, { "text": "stricture", "start": 21, "end": 30, "id": 5 }, { "text": "due", "start": 31, "end": 34, "id": 6 }, { "text": "to", "start": 35, "end": 37, "id": 7 }, { "text": "intrahepatic", "start": 38, "end": 50, "id": 8 }, { "text": "duct", "start": 51, "end": 55, "id": 9 }, { "text": "stones", "start": 56, "end": 62, "id": 10 }, { "text": "3", "start": 63, "end": 64, "id": 11 }, { "text": "years", "start": 65, "end": 70, "id": 12 }, { "text": "after", "start": 71, "end": 76, "id": 13 }, { "text": "left", "start": 77, "end": 81, "id": 14 }, { "text": "lobectomy", "start": 82, "end": 91, "id": 15 }, { "text": "in", "start": 92, "end": 94, "id": 16 }, { "text": "a", "start": 95, "end": 96, "id": 17 }, { "text": "50-year", "start": 97, "end": 104, "id": 18 }, { "text": "-", "start": 104, "end": 105, "id": 19 }, { "text": "old", "start": 105, "end": 108, "id": 20 }, { "text": "man", "start": 109, "end": 112, "id": 21 }, { "text": "who", "start": 113, "end": 116, "id": 22 }, { "text": "presented", "start": 117, "end": 126, "id": 23 }, { "text": "with", "start": 127, "end": 131, "id": 24 }, { "text": "jaundice", "start": 132, "end": 140, "id": 25 }, { "text": ".", "start": 140, "end": 141, "id": 26 }, { "text": "The", "start": 142, "end": 145, "id": 27 }, { "text": "patient", "start": 146, "end": 153, "id": 28 }, { "text": "'s", "start": 153, "end": 155, "id": 29 }, { "text": "serum", "start": 156, "end": 161, "id": 30 }, { "text": "bilirubin", "start": 162, "end": 171, "id": 31 }, { "text": "level", "start": 172, "end": 177, "id": 32 }, { "text": "was", "start": 178, "end": 181, "id": 33 }, { "text": "elevated", "start": 182, "end": 190, "id": 34 }, { "text": "(", "start": 191, "end": 192, "id": 35 }, { "text": "12.43", "start": 192, "end": 197, "id": 36 }, { "text": "mg", "start": 198, "end": 200, "id": 37 }, { "text": "/", "start": 200, "end": 201, "id": 38 }, { "text": "dL", "start": 201, "end": 203, "id": 39 }, { "text": "[", "start": 204, "end": 205, "id": 40 }, { "text": "212.6", "start": 205, "end": 210, "id": 41 }, { "text": "µmol", "start": 211, "end": 215, "id": 42 }, { "text": "/", "start": 215, "end": 216, "id": 43 }, { "text": "L", "start": 216, "end": 217, "id": 44 }, { "text": "]", "start": 217, "end": 218, "id": 45 }, { "text": ")", "start": 218, "end": 219, "id": 46 }, { "text": ".", "start": 219, "end": 220, "id": 47 }, { "text": "(", "start": 221, "end": 222, "id": 48 }, { "text": "a", "start": 222, "end": 223, "id": 49 }, { "text": ")", "start": 223, "end": 224, "id": 50 }, { "text": "Coronal", "start": 225, "end": 232, "id": 51 }, { "text": "T2-weighted", "start": 233, "end": 244, "id": 52 }, { "text": "RARE", "start": 245, "end": 249, "id": 53 }, { "text": "image", "start": 250, "end": 255, "id": 54 }, { "text": "shows", "start": 256, "end": 261, "id": 55 }, { "text": "a", "start": 262, "end": 263, "id": 56 }, { "text": "stricture", "start": 264, "end": 273, "id": 57 }, { "text": "(", "start": 274, "end": 275, "id": 58 }, { "text": "arrow", "start": 275, "end": 280, "id": 59 }, { "text": ")", "start": 280, "end": 281, "id": 60 }, { "text": "and", "start": 282, "end": 285, "id": 61 }, { "text": "dilatation", "start": 286, "end": 296, "id": 62 }, { "text": "of", "start": 297, "end": 299, "id": 63 }, { "text": "the", "start": 300, "end": 303, "id": 64 }, { "text": "proximal", "start": 304, "end": 312, "id": 65 }, { "text": "intrahepatic", "start": 313, "end": 325, "id": 66 }, { "text": "ducts", "start": 326, "end": 331, "id": 67 }, { "text": ".", "start": 331, "end": 332, "id": 68 }, { "text": "(", "start": 333, "end": 334, "id": 69 }, { "text": "b", "start": 334, "end": 335, "id": 70 }, { "text": ")", "start": 335, "end": 336, "id": 71 }, { "text": "Gd", "start": 337, "end": 339, "id": 72 }, { "text": "-", "start": 339, "end": 340, "id": 73 }, { "text": "EOB", "start": 340, "end": 343, "id": 74 }, { "text": "-", "start": 343, "end": 344, "id": 75 }, { "text": "DTPA", "start": 344, "end": 348, "id": 76 }, { "text": "-", "start": 348, "end": 349, "id": 77 }, { "text": "enhanced", "start": 349, "end": 357, "id": 78 }, { "text": "T1-weighted", "start": 358, "end": 369, "id": 79 }, { "text": "3D", "start": 370, "end": 372, "id": 80 }, { "text": "GRE", "start": 373, "end": 376, "id": 81 }, { "text": "image", "start": 377, "end": 382, "id": 82 }, { "text": "obtained", "start": 383, "end": 391, "id": 83 }, { "text": "60", "start": 392, "end": 394, "id": 84 }, { "text": "minutes", "start": 395, "end": 402, "id": 85 }, { "text": "after", "start": 403, "end": 408, "id": 86 }, { "text": "injection", "start": 409, "end": 418, "id": 87 }, { "text": "shows", "start": 419, "end": 424, "id": 88 }, { "text": "no", "start": 425, "end": 427, "id": 89 }, { "text": "excretion", "start": 428, "end": 437, "id": 90 }, { "text": "of", "start": 438, "end": 440, "id": 91 }, { "text": "contrast", "start": 441, "end": 449, "id": 92 }, { "text": "material", "start": 450, "end": 458, "id": 93 }, { "text": "into", "start": 459, "end": 463, "id": 94 }, { "text": "the", "start": 464, "end": 467, "id": 95 }, { "text": "right", "start": 468, "end": 473, "id": 96 }, { "text": "main", "start": 474, "end": 478, "id": 97 }, { "text": "hepatic", "start": 479, "end": 486, "id": 98 }, { "text": "duct", "start": 487, "end": 491, "id": 99 }, { "text": "(", "start": 492, "end": 493, "id": 100 }, { "text": "arrow", "start": 493, "end": 498, "id": 101 }, { "text": ")", "start": 498, "end": 499, "id": 102 }, { "text": ".", "start": 499, "end": 500, "id": 103 }, { "text": "(", "start": 501, "end": 502, "id": 104 }, { "text": "c", "start": 502, "end": 503, "id": 105 }, { "text": ")", "start": 503, "end": 504, "id": 106 }, { "text": "Image", "start": 505, "end": 510, "id": 107 }, { "text": "from", "start": 511, "end": 515, "id": 108 }, { "text": "direct", "start": 516, "end": 522, "id": 109 }, { "text": "cholangiography", "start": 523, "end": 538, "id": 110 }, { "text": "shows", "start": 539, "end": 544, "id": 111 }, { "text": "the", "start": 545, "end": 548, "id": 112 }, { "text": "high", "start": 549, "end": 553, "id": 113 }, { "text": "-", "start": 553, "end": 554, "id": 114 }, { "text": "grade", "start": 554, "end": 559, "id": 115 }, { "text": "stricture", "start": 560, "end": 569, "id": 116 }, { "text": "(", "start": 570, "end": 571, "id": 117 }, { "text": "arrow", "start": 571, "end": 576, "id": 118 }, { "text": ")", "start": 576, "end": 577, "id": 119 }, { "text": "of", "start": 578, "end": 580, "id": 120 }, { "text": "the", "start": 581, "end": 584, "id": 121 }, { "text": "right", "start": 585, "end": 590, "id": 122 }, { "text": "main", "start": 591, "end": 595, "id": 123 }, { "text": "hepatic", "start": 596, "end": 603, "id": 124 }, { "text": "duct", "start": 604, "end": 608, "id": 125 }, { "text": ".", "start": 608, "end": 609, "id": 126 } ]
323ba82475cf922dcb01eb28d99bf5a15af92d9f
Figure1
5-Figure1-1.png
Fig. 1. (a) Computed tomography showed small intraabdominal nodules. (b) Fluorodeoxyglucose-positron emission tomography showed an abnormal uptake in the intraabdominal nodules.
1,122
402
{ "a": [ 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 ], "b": [ 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "ec693297-3901-4764-94ab-405d6972a5a2", "label": "a", "points": [ [ 1.8, 0 ], [ 1.8, 398.8 ], [ 556.6, 398.8 ], [ 556.6, 0 ] ], "color": "yellow" }, { "id": "3ec8dcc8-bdf3-4066-960a-b05414426fe9", "label": "b", "points": [ [ 1120.3, 0 ], [ 1120.3, 400.6 ], [ 563.7, 400.6 ], [ 563.7, 0 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "1", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "(", "start": 8, "end": 9, "id": 4 }, { "text": "a", "start": 9, "end": 10, "id": 5 }, { "text": ")", "start": 10, "end": 11, "id": 6 }, { "text": "Computed", "start": 12, "end": 20, "id": 7 }, { "text": "tomography", "start": 21, "end": 31, "id": 8 }, { "text": "showed", "start": 32, "end": 38, "id": 9 }, { "text": "small", "start": 39, "end": 44, "id": 10 }, { "text": "intraabdominal", "start": 45, "end": 59, "id": 11 }, { "text": "nodules", "start": 60, "end": 67, "id": 12 }, { "text": ".", "start": 67, "end": 68, "id": 13 }, { "text": "(", "start": 69, "end": 70, "id": 14 }, { "text": "b", "start": 70, "end": 71, "id": 15 }, { "text": ")", "start": 71, "end": 72, "id": 16 }, { "text": "Fluorodeoxyglucose", "start": 73, "end": 91, "id": 17 }, { "text": "-", "start": 91, "end": 92, "id": 18 }, { "text": "positron", "start": 92, "end": 100, "id": 19 }, { "text": "emission", "start": 101, "end": 109, "id": 20 }, { "text": "tomography", "start": 110, "end": 120, "id": 21 }, { "text": "showed", "start": 121, "end": 127, "id": 22 }, { "text": "an", "start": 128, "end": 130, "id": 23 }, { "text": "abnormal", "start": 131, "end": 139, "id": 24 }, { "text": "uptake", "start": 140, "end": 146, "id": 25 }, { "text": "in", "start": 147, "end": 149, "id": 26 }, { "text": "the", "start": 150, "end": 153, "id": 27 }, { "text": "intraabdominal", "start": 154, "end": 168, "id": 28 }, { "text": "nodules", "start": 169, "end": 176, "id": 29 }, { "text": ".", "start": 176, "end": 177, "id": 30 } ]
98a11f6aa5dfdeed24cd48b8f38a3ed6cb8782d7
Figure4
6-Figure4-1.png
Fig. 4. Dark-field photomicrograph to show the distribution of 5-HT 1A receptor mRNA expression in the vicinity of the paraventricular nucleus of the hypothalamus (PVH) (A). Dashed line defines the nuclear border of the PVH to emphasise the absence of the transcript relative to the distinct cluster of 5-HT 1A receptor expressing cells within the zona incerta (ZI). Scatterplot (B) showing a significant positive correlation between plasma oestradiol concentrations and 5-HT 1A mRNA levels in the ZI of females. 3V, third ventricle. Adapted with permission from Goel et al. (83).
474
744
{ "a": [ 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69 ], "b": [ 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "661a2aa9-caf7-425f-ae8d-0a16f8d80e69", "label": "a", "points": [ [ 0, -0.2 ], [ 0, 323.8 ], [ 470, 323.8 ], [ 470, -0.2 ] ], "color": "yellow" }, { "id": "9525be56-5204-4781-8041-fb9b630847a4", "label": "b", "points": [ [ 2, 344.8 ], [ 2, 739.8 ], [ 464, 739.8 ], [ 464, 344.8 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "4", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "Dark", "start": 8, "end": 12, "id": 4 }, { "text": "-", "start": 12, "end": 13, "id": 5 }, { "text": "field", "start": 13, "end": 18, "id": 6 }, { "text": "photomicrograph", "start": 19, "end": 34, "id": 7 }, { "text": "to", "start": 35, "end": 37, "id": 8 }, { "text": "show", "start": 38, "end": 42, "id": 9 }, { "text": "the", "start": 43, "end": 46, "id": 10 }, { "text": "distribution", "start": 47, "end": 59, "id": 11 }, { "text": "of", "start": 60, "end": 62, "id": 12 }, { "text": "5-HT", "start": 63, "end": 67, "id": 13 }, { "text": "1A", "start": 68, "end": 70, "id": 14 }, { "text": "receptor", "start": 71, "end": 79, "id": 15 }, { "text": "mRNA", "start": 80, "end": 84, "id": 16 }, { "text": "expression", "start": 85, "end": 95, "id": 17 }, { "text": "in", "start": 96, "end": 98, "id": 18 }, { "text": "the", "start": 99, "end": 102, "id": 19 }, { "text": "vicinity", "start": 103, "end": 111, "id": 20 }, { "text": "of", "start": 112, "end": 114, "id": 21 }, { "text": "the", "start": 115, "end": 118, "id": 22 }, { "text": "paraventricular", "start": 119, "end": 134, "id": 23 }, { "text": "nucleus", "start": 135, "end": 142, "id": 24 }, { "text": "of", "start": 143, "end": 145, "id": 25 }, { "text": "the", "start": 146, "end": 149, "id": 26 }, { "text": "hypothalamus", "start": 150, "end": 162, "id": 27 }, { "text": "(", "start": 163, "end": 164, "id": 28 }, { "text": "PVH", "start": 164, "end": 167, "id": 29 }, { "text": ")", "start": 167, "end": 168, "id": 30 }, { "text": "(", "start": 169, "end": 170, "id": 31 }, { "text": "A", "start": 170, "end": 171, "id": 32 }, { "text": ")", "start": 171, "end": 172, "id": 33 }, { "text": ".", "start": 172, "end": 173, "id": 34 }, { "text": "Dashed", "start": 174, "end": 180, "id": 35 }, { "text": "line", "start": 181, "end": 185, "id": 36 }, { "text": "defines", "start": 186, "end": 193, "id": 37 }, { "text": "the", "start": 194, "end": 197, "id": 38 }, { "text": "nuclear", "start": 198, "end": 205, "id": 39 }, { "text": "border", "start": 206, "end": 212, "id": 40 }, { "text": "of", "start": 213, "end": 215, "id": 41 }, { "text": "the", "start": 216, "end": 219, "id": 42 }, { "text": "PVH", "start": 220, "end": 223, "id": 43 }, { "text": "to", "start": 224, "end": 226, "id": 44 }, { "text": "emphasise", "start": 227, "end": 236, "id": 45 }, { "text": "the", "start": 237, "end": 240, "id": 46 }, { "text": "absence", "start": 241, "end": 248, "id": 47 }, { "text": "of", "start": 249, "end": 251, "id": 48 }, { "text": "the", "start": 252, "end": 255, "id": 49 }, { "text": "transcript", "start": 256, "end": 266, "id": 50 }, { "text": "relative", "start": 267, "end": 275, "id": 51 }, { "text": "to", "start": 276, "end": 278, "id": 52 }, { "text": "the", "start": 279, "end": 282, "id": 53 }, { "text": "distinct", "start": 283, "end": 291, "id": 54 }, { "text": "cluster", "start": 292, "end": 299, "id": 55 }, { "text": "of", "start": 300, "end": 302, "id": 56 }, { "text": "5-HT", "start": 303, "end": 307, "id": 57 }, { "text": "1A", "start": 308, "end": 310, "id": 58 }, { "text": "receptor", "start": 311, "end": 319, "id": 59 }, { "text": "expressing", "start": 320, "end": 330, "id": 60 }, { "text": "cells", "start": 331, "end": 336, "id": 61 }, { "text": "within", "start": 337, "end": 343, "id": 62 }, { "text": "the", "start": 344, "end": 347, "id": 63 }, { "text": "zona", "start": 348, "end": 352, "id": 64 }, { "text": "incerta", "start": 353, "end": 360, "id": 65 }, { "text": "(", "start": 361, "end": 362, "id": 66 }, { "text": "ZI", "start": 362, "end": 364, "id": 67 }, { "text": ")", "start": 364, "end": 365, "id": 68 }, { "text": ".", "start": 365, "end": 366, "id": 69 }, { "text": "Scatterplot", "start": 367, "end": 378, "id": 70 }, { "text": "(", "start": 379, "end": 380, "id": 71 }, { "text": "B", "start": 380, "end": 381, "id": 72 }, { "text": ")", "start": 381, "end": 382, "id": 73 }, { "text": "showing", "start": 383, "end": 390, "id": 74 }, { "text": "a", "start": 391, "end": 392, "id": 75 }, { "text": "significant", "start": 393, "end": 404, "id": 76 }, { "text": "positive", "start": 405, "end": 413, "id": 77 }, { "text": "correlation", "start": 414, "end": 425, "id": 78 }, { "text": "between", "start": 426, "end": 433, "id": 79 }, { "text": "plasma", "start": 434, "end": 440, "id": 80 }, { "text": "oestradiol", "start": 441, "end": 451, "id": 81 }, { "text": "concentrations", "start": 452, "end": 466, "id": 82 }, { "text": "and", "start": 467, "end": 470, "id": 83 }, { "text": "5-HT", "start": 471, "end": 475, "id": 84 }, { "text": "1A", "start": 476, "end": 478, "id": 85 }, { "text": "mRNA", "start": 479, "end": 483, "id": 86 }, { "text": "levels", "start": 484, "end": 490, "id": 87 }, { "text": "in", "start": 491, "end": 493, "id": 88 }, { "text": "the", "start": 494, "end": 497, "id": 89 }, { "text": "ZI", "start": 498, "end": 500, "id": 90 }, { "text": "of", "start": 501, "end": 503, "id": 91 }, { "text": "females", "start": 504, "end": 511, "id": 92 }, { "text": ".", "start": 511, "end": 512, "id": 93 }, { "text": "3V", "start": 513, "end": 515, "id": 94 }, { "text": ",", "start": 515, "end": 516, "id": 95 }, { "text": "third", "start": 517, "end": 522, "id": 96 }, { "text": "ventricle", "start": 523, "end": 532, "id": 97 }, { "text": ".", "start": 532, "end": 533, "id": 98 }, { "text": "Adapted", "start": 534, "end": 541, "id": 99 }, { "text": "with", "start": 542, "end": 546, "id": 100 }, { "text": "permission", "start": 547, "end": 557, "id": 101 }, { "text": "from", "start": 558, "end": 562, "id": 102 }, { "text": "Goel", "start": 563, "end": 567, "id": 103 }, { "text": "et", "start": 568, "end": 570, "id": 104 }, { "text": "al", "start": 571, "end": 573, "id": 105 }, { "text": ".", "start": 573, "end": 574, "id": 106 }, { "text": "(", "start": 575, "end": 576, "id": 107 }, { "text": "83", "start": 576, "end": 578, "id": 108 }, { "text": ")", "start": 578, "end": 579, "id": 109 }, { "text": ".", "start": 579, "end": 580, "id": 110 } ]
63a59ec0717f96156bb41de1b2e37194747e71ef
Figure2
3-Figure2-1.png
Fig. 2. MRI before treatment. A. Sagittal view, posterior effusion at C2. B. Axial view, hypersignal of C2 with no signs of epiduritis.
850
644
{ "a": [ 8, 9, 10, 11, 12, 13, 14, 15, 16 ], "b": [ 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "6e8d6aed-bbd3-48d1-a614-2bf2e3f835b2", "label": "a", "points": [ [ 1.3, 1.3 ], [ 1.3, 641.9 ], [ 331.7, 641.9 ], [ 331.7, 1.3 ] ], "color": "yellow" }, { "id": "d67df041-c29c-4f99-91fe-59de57b95fce", "label": "b", "points": [ [ 350.5, 1.3 ], [ 350.5, 523.7 ], [ 848.7, 523.7 ], [ 848.7, 1.3 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "2", "start": 5, "end": 6, "id": 2 }, { "text": ".", "start": 6, "end": 7, "id": 3 }, { "text": "MRI", "start": 8, "end": 11, "id": 4 }, { "text": "before", "start": 12, "end": 18, "id": 5 }, { "text": "treatment", "start": 19, "end": 28, "id": 6 }, { "text": ".", "start": 28, "end": 29, "id": 7 }, { "text": "A.", "start": 30, "end": 32, "id": 8 }, { "text": "Sagittal", "start": 33, "end": 41, "id": 9 }, { "text": "view", "start": 42, "end": 46, "id": 10 }, { "text": ",", "start": 46, "end": 47, "id": 11 }, { "text": "posterior", "start": 48, "end": 57, "id": 12 }, { "text": "effusion", "start": 58, "end": 66, "id": 13 }, { "text": "at", "start": 67, "end": 69, "id": 14 }, { "text": "C2", "start": 70, "end": 72, "id": 15 }, { "text": ".", "start": 72, "end": 73, "id": 16 }, { "text": "B.", "start": 74, "end": 76, "id": 17 }, { "text": "Axial", "start": 77, "end": 82, "id": 18 }, { "text": "view", "start": 83, "end": 87, "id": 19 }, { "text": ",", "start": 87, "end": 88, "id": 20 }, { "text": "hypersignal", "start": 89, "end": 100, "id": 21 }, { "text": "of", "start": 101, "end": 103, "id": 22 }, { "text": "C2", "start": 104, "end": 106, "id": 23 }, { "text": "with", "start": 107, "end": 111, "id": 24 }, { "text": "no", "start": 112, "end": 114, "id": 25 }, { "text": "signs", "start": 115, "end": 120, "id": 26 }, { "text": "of", "start": 121, "end": 123, "id": 27 }, { "text": "epiduritis", "start": 124, "end": 134, "id": 28 }, { "text": ".", "start": 134, "end": 135, "id": 29 } ]
c4d089f1ac85da73ba577cafe887662b1adc58ee
Figure1
4-Figure1-1.png
Figure 1. Patient 1 MRI images. All images are sagittal in midline. Panels in the left column (A,C) are T2-weighted, fast-spin echo, whereas those in the right column (B,D) are T1-weighted with contrast (T1 + Gd). Panels shown in the upper row (A,B) are postoperative, following initial gross total resection. Resection of the vertebrae caudal to S1 is indicated with the blue arrow. Panels in the lower row (C,D) were taken at time of recurrence. A large, heterogeneous mass extending rostrally almost to S1 and dorsally almost to the skin is present (blue arrows). The dimensions are almost equal to those of the tumor prior to initial resection.
704
764
{ "a": [ 15, 16, 17, 18, 19, 21, 26, 27, 28, 29, 30, 31, 53, 54, 55, 56, 57, 58, 59, 61, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87 ], "b": [ 15, 35, 36, 37, 38, 40, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 63, 65, 66, 67, 68, 69, 70, 71, 72, 73 ], "c": [ 15, 16, 17, 18, 19, 23, 25, 26, 27, 28, 29, 30, 31, 35, 36, 37, 38, 42, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 88, 89, 90, 91, 92, 94, 96, 98, 99, 100, 101, 102, 103, 104 ], "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "36cab4f6-33a3-4b47-a05c-e773b17fe877", "label": "a", "points": [ [ 27.3, 2 ], [ 27.3, 365.7 ], [ 372, 365.7 ], [ 372, 2 ] ], "color": "yellow" }, { "id": "b35412eb-9b65-410d-9ad8-98431f33b28f", "label": "b", "points": [ [ 376.5, 3.2 ], [ 376.5, 364.6 ], [ 687.9, 364.6 ], [ 687.9, 3.2 ] ], "color": "cyan" }, { "id": "9be8efa8-e32c-4d24-90ab-6dc2610d70fc", "label": "c", "points": [ [ 28.4, 370.2 ], [ 28.4, 724.9 ], [ 366.5, 724.9 ], [ 366.5, 370.2 ] ], "color": "magenta" }, { "id": "552a2a32-c8fb-46c2-a963-eb85c86c062c", "label": "d", "points": [ [ 370.9, 369 ], [ 370.9, 730.5 ], [ 690.1, 730.5 ], [ 690.1, 369 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Patient", "start": 10, "end": 17, "id": 3 }, { "text": "1", "start": 18, "end": 19, "id": 4 }, { "text": "MRI", "start": 20, "end": 23, "id": 5 }, { "text": "images", "start": 24, "end": 30, "id": 6 }, { "text": ".", "start": 30, "end": 31, "id": 7 }, { "text": "All", "start": 32, "end": 35, "id": 8 }, { "text": "images", "start": 36, "end": 42, "id": 9 }, { "text": "are", "start": 43, "end": 46, "id": 10 }, { "text": "sagittal", "start": 47, "end": 55, "id": 11 }, { "text": "in", "start": 56, "end": 58, "id": 12 }, { "text": "midline", "start": 59, "end": 66, "id": 13 }, { "text": ".", "start": 66, "end": 67, "id": 14 }, { "text": "Panels", "start": 68, "end": 74, "id": 15 }, { "text": "in", "start": 75, "end": 77, "id": 16 }, { "text": "the", "start": 78, "end": 81, "id": 17 }, { "text": "left", "start": 82, "end": 86, "id": 18 }, { "text": "column", "start": 87, "end": 93, "id": 19 }, { "text": "(", "start": 94, "end": 95, "id": 20 }, { "text": "A", "start": 95, "end": 96, "id": 21 }, { "text": ",", "start": 96, "end": 97, "id": 22 }, { "text": "C", "start": 97, "end": 98, "id": 23 }, { "text": ")", "start": 98, "end": 99, "id": 24 }, { "text": "are", "start": 100, "end": 103, "id": 25 }, { "text": "T2-weighted", "start": 104, "end": 115, "id": 26 }, { "text": ",", "start": 115, "end": 116, "id": 27 }, { "text": "fast", "start": 117, "end": 121, "id": 28 }, { "text": "-", "start": 121, "end": 122, "id": 29 }, { "text": "spin", "start": 122, "end": 126, "id": 30 }, { "text": "echo", "start": 127, "end": 131, "id": 31 }, { "text": ",", "start": 131, "end": 132, "id": 32 }, { "text": "whereas", "start": 133, "end": 140, "id": 33 }, { "text": "those", "start": 141, "end": 146, "id": 34 }, { "text": "in", "start": 147, "end": 149, "id": 35 }, { "text": "the", "start": 150, "end": 153, "id": 36 }, { "text": "right", "start": 154, "end": 159, "id": 37 }, { "text": "column", "start": 160, "end": 166, "id": 38 }, { "text": "(", "start": 167, "end": 168, "id": 39 }, { "text": "B", "start": 168, "end": 169, "id": 40 }, { "text": ",", "start": 169, "end": 170, "id": 41 }, { "text": "D", "start": 170, "end": 171, "id": 42 }, { "text": ")", "start": 171, "end": 172, "id": 43 }, { "text": "are", "start": 173, "end": 176, "id": 44 }, { "text": "T1-weighted", "start": 177, "end": 188, "id": 45 }, { "text": "with", "start": 189, "end": 193, "id": 46 }, { "text": "contrast", "start": 194, "end": 202, "id": 47 }, { "text": "(", "start": 203, "end": 204, "id": 48 }, { "text": "T1", "start": 204, "end": 206, "id": 49 }, { "text": "+", "start": 207, "end": 208, "id": 50 }, { "text": "Gd", "start": 209, "end": 211, "id": 51 }, { "text": ")", "start": 211, "end": 212, "id": 52 }, { "text": ".", "start": 212, "end": 213, "id": 53 }, { "text": "Panels", "start": 214, "end": 220, "id": 54 }, { "text": "shown", "start": 221, "end": 226, "id": 55 }, { "text": "in", "start": 227, "end": 229, "id": 56 }, { "text": "the", "start": 230, "end": 233, "id": 57 }, { "text": "upper", "start": 234, "end": 239, "id": 58 }, { "text": "row", "start": 240, "end": 243, "id": 59 }, { "text": "(", "start": 244, "end": 245, "id": 60 }, { "text": "A", "start": 245, "end": 246, "id": 61 }, { "text": ",", "start": 246, "end": 247, "id": 62 }, { "text": "B", "start": 247, "end": 248, "id": 63 }, { "text": ")", "start": 248, "end": 249, "id": 64 }, { "text": "are", "start": 250, "end": 253, "id": 65 }, { "text": "postoperative", "start": 254, "end": 267, "id": 66 }, { "text": ",", "start": 267, "end": 268, "id": 67 }, { "text": "following", "start": 269, "end": 278, "id": 68 }, { "text": "initial", "start": 279, "end": 286, "id": 69 }, { "text": "gross", "start": 287, "end": 292, "id": 70 }, { "text": "total", "start": 293, "end": 298, "id": 71 }, { "text": "resection", "start": 299, "end": 308, "id": 72 }, { "text": ".", "start": 308, "end": 309, "id": 73 }, { "text": "Resection", "start": 310, "end": 319, "id": 74 }, { "text": "of", "start": 320, "end": 322, "id": 75 }, { "text": "the", "start": 323, "end": 326, "id": 76 }, { "text": "vertebrae", "start": 327, "end": 336, "id": 77 }, { "text": "caudal", "start": 337, "end": 343, "id": 78 }, { "text": "to", "start": 344, "end": 346, "id": 79 }, { "text": "S1", "start": 347, "end": 349, "id": 80 }, { "text": "is", "start": 350, "end": 352, "id": 81 }, { "text": "indicated", "start": 353, "end": 362, "id": 82 }, { "text": "with", "start": 363, "end": 367, "id": 83 }, { "text": "the", "start": 368, "end": 371, "id": 84 }, { "text": "blue", "start": 372, "end": 376, "id": 85 }, { "text": "arrow", "start": 377, "end": 382, "id": 86 }, { "text": ".", "start": 382, "end": 383, "id": 87 }, { "text": "Panels", "start": 384, "end": 390, "id": 88 }, { "text": "in", "start": 391, "end": 393, "id": 89 }, { "text": "the", "start": 394, "end": 397, "id": 90 }, { "text": "lower", "start": 398, "end": 403, "id": 91 }, { "text": "row", "start": 404, "end": 407, "id": 92 }, { "text": "(", "start": 408, "end": 409, "id": 93 }, { "text": "C", "start": 409, "end": 410, "id": 94 }, { "text": ",", "start": 410, "end": 411, "id": 95 }, { "text": "D", "start": 411, "end": 412, "id": 96 }, { "text": ")", "start": 412, "end": 413, "id": 97 }, { "text": "were", "start": 414, "end": 418, "id": 98 }, { "text": "taken", "start": 419, "end": 424, "id": 99 }, { "text": "at", "start": 425, "end": 427, "id": 100 }, { "text": "time", "start": 428, "end": 432, "id": 101 }, { "text": "of", "start": 433, "end": 435, "id": 102 }, { "text": "recurrence", "start": 436, "end": 446, "id": 103 }, { "text": ".", "start": 446, "end": 447, "id": 104 }, { "text": "A", "start": 448, "end": 449, "id": 105 }, { "text": "large", "start": 450, "end": 455, "id": 106 }, { "text": ",", "start": 455, "end": 456, "id": 107 }, { "text": "heterogeneous", "start": 457, "end": 470, "id": 108 }, { "text": "mass", "start": 471, "end": 475, "id": 109 }, { "text": "extending", "start": 476, "end": 485, "id": 110 }, { "text": "rostrally", "start": 486, "end": 495, "id": 111 }, { "text": "almost", "start": 496, "end": 502, "id": 112 }, { "text": "to", "start": 503, "end": 505, "id": 113 }, { "text": "S1", "start": 506, "end": 508, "id": 114 }, { "text": "and", "start": 509, "end": 512, "id": 115 }, { "text": "dorsally", "start": 513, "end": 521, "id": 116 }, { "text": "almost", "start": 522, "end": 528, "id": 117 }, { "text": "to", "start": 529, "end": 531, "id": 118 }, { "text": "the", "start": 532, "end": 535, "id": 119 }, { "text": "skin", "start": 536, "end": 540, "id": 120 }, { "text": "is", "start": 541, "end": 543, "id": 121 }, { "text": "present", "start": 544, "end": 551, "id": 122 }, { "text": "(", "start": 552, "end": 553, "id": 123 }, { "text": "blue", "start": 553, "end": 557, "id": 124 }, { "text": "arrows", "start": 558, "end": 564, "id": 125 }, { "text": ")", "start": 564, "end": 565, "id": 126 }, { "text": ".", "start": 565, "end": 566, "id": 127 }, { "text": "The", "start": 567, "end": 570, "id": 128 }, { "text": "dimensions", "start": 571, "end": 581, "id": 129 }, { "text": "are", "start": 582, "end": 585, "id": 130 }, { "text": "almost", "start": 586, "end": 592, "id": 131 }, { "text": "equal", "start": 593, "end": 598, "id": 132 }, { "text": "to", "start": 599, "end": 601, "id": 133 }, { "text": "those", "start": 602, "end": 607, "id": 134 }, { "text": "of", "start": 608, "end": 610, "id": 135 }, { "text": "the", "start": 611, "end": 614, "id": 136 }, { "text": "tumor", "start": 615, "end": 620, "id": 137 }, { "text": "prior", "start": 621, "end": 626, "id": 138 }, { "text": "to", "start": 627, "end": 629, "id": 139 }, { "text": "initial", "start": 630, "end": 637, "id": 140 }, { "text": "resection", "start": 638, "end": 647, "id": 141 }, { "text": ".", "start": 647, "end": 648, "id": 142 } ]
b987ab7ea1728753a890a1c4c0ebe598b85a0142
Figure1
2-Figure1-1.png
Figure 1 Patient 1: (A) Sagittal and (B) transverse T2-weighted MRI with contrast of the lumbosacral spine shows a rim enhancing cystic lesion (white arrow) centrally located at the L3/4 level compressing onto the cauda equina (grey arrow). Patient 2: (C) Transverse and (D) sagittal T2-weighted MRI image shows Grade I spondylolisthesis and spinal stenosis at the L4/5 level being compressed by a huge cystic structure (white arrow) with a thick cystic wall onto the cauda equina (grey arrow).
1,238
748
{ "a": [ 2, 3, 4, 5, 6, 7, 8, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47 ], "b": [ 2, 3, 4, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47 ], "c": [ 48, 49, 50, 51, 52, 53, 54, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98 ], "d": [ 48, 49, 50, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "2b259c06-c965-4292-a167-1176db789b89", "label": "a", "points": [ [ 40.1, 21.5 ], [ 40.1, 710 ], [ 435.2, 710 ], [ 435.2, 21.5 ] ], "color": "yellow" }, { "id": "51de006a-a011-422a-a219-d6ef9d14ac17", "label": "b", "points": [ [ 446.9, 23.5 ], [ 446.9, 389.2 ], [ 937.8, 389.2 ], [ 937.8, 23.5 ] ], "color": "cyan" }, { "id": "4c2a15ec-8410-43e0-914f-7f4d327ac786", "label": "c", "points": [ [ 448.9, 397 ], [ 448.9, 711.9 ], [ 941.7, 711.9 ], [ 941.7, 397 ] ], "color": "magenta" }, { "id": "8db9658d-7e00-4f95-91f8-1d14862808fc", "label": "d", "points": [ [ 951.5, 21.5 ], [ 951.5, 713.9 ], [ 1211.6, 713.9 ], [ 1211.6, 21.5 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "1", "start": 7, "end": 8, "id": 1 }, { "text": "Patient", "start": 9, "end": 16, "id": 2 }, { "text": "1", "start": 17, "end": 18, "id": 3 }, { "text": ":", "start": 18, "end": 19, "id": 4 }, { "text": "(", "start": 20, "end": 21, "id": 5 }, { "text": "A", "start": 21, "end": 22, "id": 6 }, { "text": ")", "start": 22, "end": 23, "id": 7 }, { "text": "Sagittal", "start": 24, "end": 32, "id": 8 }, { "text": "and", "start": 33, "end": 36, "id": 9 }, { "text": "(", "start": 37, "end": 38, "id": 10 }, { "text": "B", "start": 38, "end": 39, "id": 11 }, { "text": ")", "start": 39, "end": 40, "id": 12 }, { "text": "transverse", "start": 41, "end": 51, "id": 13 }, { "text": "T2-weighted", "start": 52, "end": 63, "id": 14 }, { "text": "MRI", "start": 64, "end": 67, "id": 15 }, { "text": "with", "start": 68, "end": 72, "id": 16 }, { "text": "contrast", "start": 73, "end": 81, "id": 17 }, { "text": "of", "start": 82, "end": 84, "id": 18 }, { "text": "the", "start": 85, "end": 88, "id": 19 }, { "text": "lumbosacral", "start": 89, "end": 100, "id": 20 }, { "text": "spine", "start": 101, "end": 106, "id": 21 }, { "text": "shows", "start": 107, "end": 112, "id": 22 }, { "text": "a", "start": 113, "end": 114, "id": 23 }, { "text": "rim", "start": 115, "end": 118, "id": 24 }, { "text": "enhancing", "start": 119, "end": 128, "id": 25 }, { "text": "cystic", "start": 129, "end": 135, "id": 26 }, { "text": "lesion", "start": 136, "end": 142, "id": 27 }, { "text": "(", "start": 143, "end": 144, "id": 28 }, { "text": "white", "start": 144, "end": 149, "id": 29 }, { "text": "arrow", "start": 150, "end": 155, "id": 30 }, { "text": ")", "start": 155, "end": 156, "id": 31 }, { "text": "centrally", "start": 157, "end": 166, "id": 32 }, { "text": "located", "start": 167, "end": 174, "id": 33 }, { "text": "at", "start": 175, "end": 177, "id": 34 }, { "text": "the", "start": 178, "end": 181, "id": 35 }, { "text": "L3/4", "start": 182, "end": 186, "id": 36 }, { "text": "level", "start": 187, "end": 192, "id": 37 }, { "text": "compressing", "start": 193, "end": 204, "id": 38 }, { "text": "onto", "start": 205, "end": 209, "id": 39 }, { "text": "the", "start": 210, "end": 213, "id": 40 }, { "text": "cauda", "start": 214, "end": 219, "id": 41 }, { "text": "equina", "start": 220, "end": 226, "id": 42 }, { "text": "(", "start": 227, "end": 228, "id": 43 }, { "text": "grey", "start": 228, "end": 232, "id": 44 }, { "text": "arrow", "start": 233, "end": 238, "id": 45 }, { "text": ")", "start": 238, "end": 239, "id": 46 }, { "text": ".", "start": 239, "end": 240, "id": 47 }, { "text": "Patient", "start": 241, "end": 248, "id": 48 }, { "text": "2", "start": 249, "end": 250, "id": 49 }, { "text": ":", "start": 250, "end": 251, "id": 50 }, { "text": "(", "start": 252, "end": 253, "id": 51 }, { "text": "C", "start": 253, "end": 254, "id": 52 }, { "text": ")", "start": 254, "end": 255, "id": 53 }, { "text": "Transverse", "start": 256, "end": 266, "id": 54 }, { "text": "and", "start": 267, "end": 270, "id": 55 }, { "text": "(", "start": 271, "end": 272, "id": 56 }, { "text": "D", "start": 272, "end": 273, "id": 57 }, { "text": ")", "start": 273, "end": 274, "id": 58 }, { "text": "sagittal", "start": 275, "end": 283, "id": 59 }, { "text": "T2-weighted", "start": 284, "end": 295, "id": 60 }, { "text": "MRI", "start": 296, "end": 299, "id": 61 }, { "text": "image", "start": 300, "end": 305, "id": 62 }, { "text": "shows", "start": 306, "end": 311, "id": 63 }, { "text": "Grade", "start": 312, "end": 317, "id": 64 }, { "text": "I", "start": 318, "end": 319, "id": 65 }, { "text": "spondylolisthesis", "start": 320, "end": 337, "id": 66 }, { "text": "and", "start": 338, "end": 341, "id": 67 }, { "text": "spinal", "start": 342, "end": 348, "id": 68 }, { "text": "stenosis", "start": 349, "end": 357, "id": 69 }, { "text": "at", "start": 358, "end": 360, "id": 70 }, { "text": "the", "start": 361, "end": 364, "id": 71 }, { "text": "L4/5", "start": 365, "end": 369, "id": 72 }, { "text": "level", "start": 370, "end": 375, "id": 73 }, { "text": "being", "start": 376, "end": 381, "id": 74 }, { "text": "compressed", "start": 382, "end": 392, "id": 75 }, { "text": "by", "start": 393, "end": 395, "id": 76 }, { "text": "a", "start": 396, "end": 397, "id": 77 }, { "text": "huge", "start": 398, "end": 402, "id": 78 }, { "text": "cystic", "start": 403, "end": 409, "id": 79 }, { "text": "structure", "start": 410, "end": 419, "id": 80 }, { "text": "(", "start": 420, "end": 421, "id": 81 }, { "text": "white", "start": 421, "end": 426, "id": 82 }, { "text": "arrow", "start": 427, "end": 432, "id": 83 }, { "text": ")", "start": 432, "end": 433, "id": 84 }, { "text": "with", "start": 434, "end": 438, "id": 85 }, { "text": "a", "start": 439, "end": 440, "id": 86 }, { "text": "thick", "start": 441, "end": 446, "id": 87 }, { "text": "cystic", "start": 447, "end": 453, "id": 88 }, { "text": "wall", "start": 454, "end": 458, "id": 89 }, { "text": "onto", "start": 459, "end": 463, "id": 90 }, { "text": "the", "start": 464, "end": 467, "id": 91 }, { "text": "cauda", "start": 468, "end": 473, "id": 92 }, { "text": "equina", "start": 474, "end": 480, "id": 93 }, { "text": "(", "start": 481, "end": 482, "id": 94 }, { "text": "grey", "start": 482, "end": 486, "id": 95 }, { "text": "arrow", "start": 487, "end": 492, "id": 96 }, { "text": ")", "start": 492, "end": 493, "id": 97 }, { "text": ".", "start": 493, "end": 494, "id": 98 } ]
5dd80841cfa8fbf952df8516dd9ff3e4233b977f
Figure6
5-Figure6-1.png
Figure 6. The first transmembrane region of LBR sorts/3-galactosidase to the inner nuclear membrane. (A) COS-1 cells transfected with/3gal-TM1 (B) were fixed and permeabilized 24 h after transfection and processed for indirect immunofluorescence microscopy by staining with mouse anti-/3-galactosidase antibodies, followed by anti-mouse IgG-FITC. (B) shows the amino acid sequence encoded by the chick p58 sequence contained in the/3gal-TM1 construct. The stippled box encloses the predicted membrane spanning segment. Bar, 10 #m.
662
762
{ "a": [ 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57 ], "b": [ 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "f6772689-3a95-4a2a-b460-03a6ec6a9f0d", "label": "a", "points": [ [ 97.8, 7.1 ], [ 97.8, 484 ], [ 522.4, 484 ], [ 522.4, 7.1 ] ], "color": "yellow" }, { "id": "636fd87f-c4ab-4c9b-9952-8173618f3b82", "label": "b", "points": [ [ 2.7, 548.3 ], [ 2.7, 733.4 ], [ 655.2, 733.4 ], [ 655.2, 548.3 ] ], "color": "cyan" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "6", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "The", "start": 10, "end": 13, "id": 3 }, { "text": "first", "start": 14, "end": 19, "id": 4 }, { "text": "transmembrane", "start": 20, "end": 33, "id": 5 }, { "text": "region", "start": 34, "end": 40, "id": 6 }, { "text": "of", "start": 41, "end": 43, "id": 7 }, { "text": "LBR", "start": 44, "end": 47, "id": 8 }, { "text": "sorts/3-galactosidase", "start": 48, "end": 69, "id": 9 }, { "text": "to", "start": 70, "end": 72, "id": 10 }, { "text": "the", "start": 73, "end": 76, "id": 11 }, { "text": "inner", "start": 77, "end": 82, "id": 12 }, { "text": "nuclear", "start": 83, "end": 90, "id": 13 }, { "text": "membrane", "start": 91, "end": 99, "id": 14 }, { "text": ".", "start": 99, "end": 100, "id": 15 }, { "text": "(", "start": 101, "end": 102, "id": 16 }, { "text": "A", "start": 102, "end": 103, "id": 17 }, { "text": ")", "start": 103, "end": 104, "id": 18 }, { "text": "COS-1", "start": 105, "end": 110, "id": 19 }, { "text": "cells", "start": 111, "end": 116, "id": 20 }, { "text": "transfected", "start": 117, "end": 128, "id": 21 }, { "text": "with/3gal", "start": 129, "end": 138, "id": 22 }, { "text": "-", "start": 138, "end": 139, "id": 23 }, { "text": "TM1", "start": 139, "end": 142, "id": 24 }, { "text": "(", "start": 143, "end": 144, "id": 25 }, { "text": "B", "start": 144, "end": 145, "id": 26 }, { "text": ")", "start": 145, "end": 146, "id": 27 }, { "text": "were", "start": 147, "end": 151, "id": 28 }, { "text": "fixed", "start": 152, "end": 157, "id": 29 }, { "text": "and", "start": 158, "end": 161, "id": 30 }, { "text": "permeabilized", "start": 162, "end": 175, "id": 31 }, { "text": "24", "start": 176, "end": 178, "id": 32 }, { "text": "h", "start": 179, "end": 180, "id": 33 }, { "text": "after", "start": 181, "end": 186, "id": 34 }, { "text": "transfection", "start": 187, "end": 199, "id": 35 }, { "text": "and", "start": 200, "end": 203, "id": 36 }, { "text": "processed", "start": 204, "end": 213, "id": 37 }, { "text": "for", "start": 214, "end": 217, "id": 38 }, { "text": "indirect", "start": 218, "end": 226, "id": 39 }, { "text": "immunofluorescence", "start": 227, "end": 245, "id": 40 }, { "text": "microscopy", "start": 246, "end": 256, "id": 41 }, { "text": "by", "start": 257, "end": 259, "id": 42 }, { "text": "staining", "start": 260, "end": 268, "id": 43 }, { "text": "with", "start": 269, "end": 273, "id": 44 }, { "text": "mouse", "start": 274, "end": 279, "id": 45 }, { "text": "anti-/3-galactosidase", "start": 280, "end": 301, "id": 46 }, { "text": "antibodies", "start": 302, "end": 312, "id": 47 }, { "text": ",", "start": 312, "end": 313, "id": 48 }, { "text": "followed", "start": 314, "end": 322, "id": 49 }, { "text": "by", "start": 323, "end": 325, "id": 50 }, { "text": "anti", "start": 326, "end": 330, "id": 51 }, { "text": "-", "start": 330, "end": 331, "id": 52 }, { "text": "mouse", "start": 331, "end": 336, "id": 53 }, { "text": "IgG", "start": 337, "end": 340, "id": 54 }, { "text": "-", "start": 340, "end": 341, "id": 55 }, { "text": "FITC", "start": 341, "end": 345, "id": 56 }, { "text": ".", "start": 345, "end": 346, "id": 57 }, { "text": "(", "start": 347, "end": 348, "id": 58 }, { "text": "B", "start": 348, "end": 349, "id": 59 }, { "text": ")", "start": 349, "end": 350, "id": 60 }, { "text": "shows", "start": 351, "end": 356, "id": 61 }, { "text": "the", "start": 357, "end": 360, "id": 62 }, { "text": "amino", "start": 361, "end": 366, "id": 63 }, { "text": "acid", "start": 367, "end": 371, "id": 64 }, { "text": "sequence", "start": 372, "end": 380, "id": 65 }, { "text": "encoded", "start": 381, "end": 388, "id": 66 }, { "text": "by", "start": 389, "end": 391, "id": 67 }, { "text": "the", "start": 392, "end": 395, "id": 68 }, { "text": "chick", "start": 396, "end": 401, "id": 69 }, { "text": "p58", "start": 402, "end": 405, "id": 70 }, { "text": "sequence", "start": 406, "end": 414, "id": 71 }, { "text": "contained", "start": 415, "end": 424, "id": 72 }, { "text": "in", "start": 425, "end": 427, "id": 73 }, { "text": "the/3gal", "start": 428, "end": 436, "id": 74 }, { "text": "-", "start": 436, "end": 437, "id": 75 }, { "text": "TM1", "start": 437, "end": 440, "id": 76 }, { "text": "construct", "start": 441, "end": 450, "id": 77 }, { "text": ".", "start": 450, "end": 451, "id": 78 }, { "text": "The", "start": 452, "end": 455, "id": 79 }, { "text": "stippled", "start": 456, "end": 464, "id": 80 }, { "text": "box", "start": 465, "end": 468, "id": 81 }, { "text": "encloses", "start": 469, "end": 477, "id": 82 }, { "text": "the", "start": 478, "end": 481, "id": 83 }, { "text": "predicted", "start": 482, "end": 491, "id": 84 }, { "text": "membrane", "start": 492, "end": 500, "id": 85 }, { "text": "spanning", "start": 501, "end": 509, "id": 86 }, { "text": "segment", "start": 510, "end": 517, "id": 87 }, { "text": ".", "start": 517, "end": 518, "id": 88 }, { "text": "Bar", "start": 519, "end": 522, "id": 89 }, { "text": ",", "start": 522, "end": 523, "id": 90 }, { "text": "10", "start": 524, "end": 526, "id": 91 }, { "text": "#", "start": 527, "end": 528, "id": 92 }, { "text": "m.", "start": 528, "end": 530, "id": 93 } ]
38a7221418ac93b8c67a6f35f366040e8e563efb
Figure2
3-Figure2-1.png
Figure 2. Genome organization is dominated by folding of chromatin into large-scale chromatin domains. (A) HeLa cells imaged live by deconvolution light microscopy using Hoechst DNA staining. (B) TEM image of HeLa cell nucleus in permeabilized cell reveals large-scale chromatin domains with heavy metal staining. Bar, 500 nm. (C) Computational slice from EM tomography reconstruction reveals large-scale chromatin fiberlike domains formed by the folding of 10-nm and 30-nm chromatin, corresponding to hundreds to thousands of kilobases of DNA. Bar, 200 nm. (D) Similar large-scale chromatin organization is visualized by TEM energy-loss imaging of the phosphorus distribution within cells fixed directly without permeabilization. (Image courtesy of Michael Hendzel, University of Alberta.)
732
764
{ "a": [ 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33 ], "b": [ 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61 ], "c": [ 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102 ], "d": [ 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "04696331-7462-405e-b535-51b004f6b050", "label": "a", "points": [ [ 360.2, 388.3 ], [ 360.2, -0.2 ], [ 1.8, -0.2 ], [ 1.8, 388.3 ] ], "color": "yellow" }, { "id": "570b9ab0-12c1-4d7c-8a76-2aba0811f3f7", "label": "b", "points": [ [ 375.3, 2.1 ], [ 375.3, 393 ], [ 729.1, 393 ], [ 729.1, 2.1 ] ], "color": "cyan" }, { "id": "a975ef28-ed9f-403c-ac9d-2682155f14fc", "label": "c", "points": [ [ 0.6, 401.1 ], [ 0.6, 761.8 ], [ 359.1, 761.8 ], [ 359.1, 401.1 ] ], "color": "magenta" }, { "id": "aeed19aa-589e-4b3e-b4a0-f3399fdc706b", "label": "d", "points": [ [ 374.1, 404.5 ], [ 374.1, 760.7 ], [ 730.3, 760.7 ], [ 730.3, 404.5 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "2", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "Genome", "start": 10, "end": 16, "id": 3 }, { "text": "organization", "start": 17, "end": 29, "id": 4 }, { "text": "is", "start": 30, "end": 32, "id": 5 }, { "text": "dominated", "start": 33, "end": 42, "id": 6 }, { "text": "by", "start": 43, "end": 45, "id": 7 }, { "text": "folding", "start": 46, "end": 53, "id": 8 }, { "text": "of", "start": 54, "end": 56, "id": 9 }, { "text": "chromatin", "start": 57, "end": 66, "id": 10 }, { "text": "into", "start": 67, "end": 71, "id": 11 }, { "text": "large", "start": 72, "end": 77, "id": 12 }, { "text": "-", "start": 77, "end": 78, "id": 13 }, { "text": "scale", "start": 78, "end": 83, "id": 14 }, { "text": "chromatin", "start": 84, "end": 93, "id": 15 }, { "text": "domains", "start": 94, "end": 101, "id": 16 }, { "text": ".", "start": 101, "end": 102, "id": 17 }, { "text": "(", "start": 103, "end": 104, "id": 18 }, { "text": "A", "start": 104, "end": 105, "id": 19 }, { "text": ")", "start": 105, "end": 106, "id": 20 }, { "text": "HeLa", "start": 107, "end": 111, "id": 21 }, { "text": "cells", "start": 112, "end": 117, "id": 22 }, { "text": "imaged", "start": 118, "end": 124, "id": 23 }, { "text": "live", "start": 125, "end": 129, "id": 24 }, { "text": "by", "start": 130, "end": 132, "id": 25 }, { "text": "deconvolution", "start": 133, "end": 146, "id": 26 }, { "text": "light", "start": 147, "end": 152, "id": 27 }, { "text": "microscopy", "start": 153, "end": 163, "id": 28 }, { "text": "using", "start": 164, "end": 169, "id": 29 }, { "text": "Hoechst", "start": 170, "end": 177, "id": 30 }, { "text": "DNA", "start": 178, "end": 181, "id": 31 }, { "text": "staining", "start": 182, "end": 190, "id": 32 }, { "text": ".", "start": 190, "end": 191, "id": 33 }, { "text": "(", "start": 192, "end": 193, "id": 34 }, { "text": "B", "start": 193, "end": 194, "id": 35 }, { "text": ")", "start": 194, "end": 195, "id": 36 }, { "text": "TEM", "start": 196, "end": 199, "id": 37 }, { "text": "image", "start": 200, "end": 205, "id": 38 }, { "text": "of", "start": 206, "end": 208, "id": 39 }, { "text": "HeLa", "start": 209, "end": 213, "id": 40 }, { "text": "cell", "start": 214, "end": 218, "id": 41 }, { "text": "nucleus", "start": 219, "end": 226, "id": 42 }, { "text": "in", "start": 227, "end": 229, "id": 43 }, { "text": "permeabilized", "start": 230, "end": 243, "id": 44 }, { "text": "cell", "start": 244, "end": 248, "id": 45 }, { "text": "reveals", "start": 249, "end": 256, "id": 46 }, { "text": "large", "start": 257, "end": 262, "id": 47 }, { "text": "-", "start": 262, "end": 263, "id": 48 }, { "text": "scale", "start": 263, "end": 268, "id": 49 }, { "text": "chromatin", "start": 269, "end": 278, "id": 50 }, { "text": "domains", "start": 279, "end": 286, "id": 51 }, { "text": "with", "start": 287, "end": 291, "id": 52 }, { "text": "heavy", "start": 292, "end": 297, "id": 53 }, { "text": "metal", "start": 298, "end": 303, "id": 54 }, { "text": "staining", "start": 304, "end": 312, "id": 55 }, { "text": ".", "start": 312, "end": 313, "id": 56 }, { "text": "Bar", "start": 314, "end": 317, "id": 57 }, { "text": ",", "start": 317, "end": 318, "id": 58 }, { "text": "500", "start": 319, "end": 322, "id": 59 }, { "text": "nm", "start": 323, "end": 325, "id": 60 }, { "text": ".", "start": 325, "end": 326, "id": 61 }, { "text": "(", "start": 327, "end": 328, "id": 62 }, { "text": "C", "start": 328, "end": 329, "id": 63 }, { "text": ")", "start": 329, "end": 330, "id": 64 }, { "text": "Computational", "start": 331, "end": 344, "id": 65 }, { "text": "slice", "start": 345, "end": 350, "id": 66 }, { "text": "from", "start": 351, "end": 355, "id": 67 }, { "text": "EM", "start": 356, "end": 358, "id": 68 }, { "text": "tomography", "start": 359, "end": 369, "id": 69 }, { "text": "reconstruction", "start": 370, "end": 384, "id": 70 }, { "text": "reveals", "start": 385, "end": 392, "id": 71 }, { "text": "large", "start": 393, "end": 398, "id": 72 }, { "text": "-", "start": 398, "end": 399, "id": 73 }, { "text": "scale", "start": 399, "end": 404, "id": 74 }, { "text": "chromatin", "start": 405, "end": 414, "id": 75 }, { "text": "fiberlike", "start": 415, "end": 424, "id": 76 }, { "text": "domains", "start": 425, "end": 432, "id": 77 }, { "text": "formed", "start": 433, "end": 439, "id": 78 }, { "text": "by", "start": 440, "end": 442, "id": 79 }, { "text": "the", "start": 443, "end": 446, "id": 80 }, { "text": "folding", "start": 447, "end": 454, "id": 81 }, { "text": "of", "start": 455, "end": 457, "id": 82 }, { "text": "10-nm", "start": 458, "end": 463, "id": 83 }, { "text": "and", "start": 464, "end": 467, "id": 84 }, { "text": "30-nm", "start": 468, "end": 473, "id": 85 }, { "text": "chromatin", "start": 474, "end": 483, "id": 86 }, { "text": ",", "start": 483, "end": 484, "id": 87 }, { "text": "corresponding", "start": 485, "end": 498, "id": 88 }, { "text": "to", "start": 499, "end": 501, "id": 89 }, { "text": "hundreds", "start": 502, "end": 510, "id": 90 }, { "text": "to", "start": 511, "end": 513, "id": 91 }, { "text": "thousands", "start": 514, "end": 523, "id": 92 }, { "text": "of", "start": 524, "end": 526, "id": 93 }, { "text": "kilobases", "start": 527, "end": 536, "id": 94 }, { "text": "of", "start": 537, "end": 539, "id": 95 }, { "text": "DNA", "start": 540, "end": 543, "id": 96 }, { "text": ".", "start": 543, "end": 544, "id": 97 }, { "text": "Bar", "start": 545, "end": 548, "id": 98 }, { "text": ",", "start": 548, "end": 549, "id": 99 }, { "text": "200", "start": 550, "end": 553, "id": 100 }, { "text": "nm", "start": 554, "end": 556, "id": 101 }, { "text": ".", "start": 556, "end": 557, "id": 102 }, { "text": "(", "start": 558, "end": 559, "id": 103 }, { "text": "D", "start": 559, "end": 560, "id": 104 }, { "text": ")", "start": 560, "end": 561, "id": 105 }, { "text": "Similar", "start": 562, "end": 569, "id": 106 }, { "text": "large", "start": 570, "end": 575, "id": 107 }, { "text": "-", "start": 575, "end": 576, "id": 108 }, { "text": "scale", "start": 576, "end": 581, "id": 109 }, { "text": "chromatin", "start": 582, "end": 591, "id": 110 }, { "text": "organization", "start": 592, "end": 604, "id": 111 }, { "text": "is", "start": 605, "end": 607, "id": 112 }, { "text": "visualized", "start": 608, "end": 618, "id": 113 }, { "text": "by", "start": 619, "end": 621, "id": 114 }, { "text": "TEM", "start": 622, "end": 625, "id": 115 }, { "text": "energy", "start": 626, "end": 632, "id": 116 }, { "text": "-", "start": 632, "end": 633, "id": 117 }, { "text": "loss", "start": 633, "end": 637, "id": 118 }, { "text": "imaging", "start": 638, "end": 645, "id": 119 }, { "text": "of", "start": 646, "end": 648, "id": 120 }, { "text": "the", "start": 649, "end": 652, "id": 121 }, { "text": "phosphorus", "start": 653, "end": 663, "id": 122 }, { "text": "distribution", "start": 664, "end": 676, "id": 123 }, { "text": "within", "start": 677, "end": 683, "id": 124 }, { "text": "cells", "start": 684, "end": 689, "id": 125 }, { "text": "fixed", "start": 690, "end": 695, "id": 126 }, { "text": "directly", "start": 696, "end": 704, "id": 127 }, { "text": "without", "start": 705, "end": 712, "id": 128 }, { "text": "permeabilization", "start": 713, "end": 729, "id": 129 }, { "text": ".", "start": 729, "end": 730, "id": 130 }, { "text": "(", "start": 731, "end": 732, "id": 131 }, { "text": "Image", "start": 732, "end": 737, "id": 132 }, { "text": "courtesy", "start": 738, "end": 746, "id": 133 }, { "text": "of", "start": 747, "end": 749, "id": 134 }, { "text": "Michael", "start": 750, "end": 757, "id": 135 }, { "text": "Hendzel", "start": 758, "end": 765, "id": 136 }, { "text": ",", "start": 765, "end": 766, "id": 137 }, { "text": "University", "start": 767, "end": 777, "id": 138 }, { "text": "of", "start": 778, "end": 780, "id": 139 }, { "text": "Alberta", "start": 781, "end": 788, "id": 140 }, { "text": ".", "start": 788, "end": 789, "id": 141 }, { "text": ")", "start": 789, "end": 790, "id": 142 } ]
d0dc476dc658cc8c8c55439d6d319c03420e7c48
Figure8
5-Figure8-1.png
Figure 8. a–d. Malignant phyllodes tumor. Axial T2-weighted image (a) shows an irregular and markedly hyperintense lesion (arrow) compared with fibroglandular tissue. Subtraction image (b) reveals heterogeneous enhancement (arrow). The lesion demonstrated wash-out kinetic (not shown). The lesion was categorized as BI-RADS category 4c. Histopathologic examination (c, H-E, ×20) demonstrates leaf-like pattern consisting of slits lined with double stratified epithelium (arrows) surrounded by stromal proliferation and (d, H-E, ×100) increased number of atypical mitosis (arrows) of malignant phylloid tumor.
1,418
272
{ "a": [ 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31 ], "b": [ 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43 ], "c": [ 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97 ], "d": [ 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120 ], "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "3cdd250d-f4ca-4348-a3a9-7b82a168a14d", "label": "a", "points": [ [ 3.4, 4.1 ], [ 3.4, 250.5 ], [ 339.4, 250.5 ], [ 339.4, 4.1 ] ], "color": "yellow" }, { "id": "ecb365cb-ea17-4831-a452-6d1aa619f2a2", "label": "b", "points": [ [ 359.6, 4.1 ], [ 359.6, 246 ], [ 688.9, 246 ], [ 688.9, 4.1 ] ], "color": "cyan" }, { "id": "e8c2eb59-2cf5-4d7a-a5f1-2c9b00a18d6c", "label": "c", "points": [ [ 718, 1.9 ], [ 718, 241.6 ], [ 1063, 241.6 ], [ 1063, 1.9 ] ], "color": "magenta" }, { "id": "2a62f61a-1500-44ae-851c-0b0b2fbcb520", "label": "d", "points": [ [ 1087.6, 6.4 ], [ 1087.6, 241.6 ], [ 1407.9, 241.6 ], [ 1407.9, 6.4 ] ], "color": "springgreen" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "8", "start": 7, "end": 8, "id": 1 }, { "text": ".", "start": 8, "end": 9, "id": 2 }, { "text": "a", "start": 10, "end": 11, "id": 3 }, { "text": "–", "start": 11, "end": 12, "id": 4 }, { "text": "d", "start": 12, "end": 13, "id": 5 }, { "text": ".", "start": 13, "end": 14, "id": 6 }, { "text": "Malignant", "start": 15, "end": 24, "id": 7 }, { "text": "phyllodes", "start": 25, "end": 34, "id": 8 }, { "text": "tumor", "start": 35, "end": 40, "id": 9 }, { "text": ".", "start": 40, "end": 41, "id": 10 }, { "text": "Axial", "start": 42, "end": 47, "id": 11 }, { "text": "T2-weighted", "start": 48, "end": 59, "id": 12 }, { "text": "image", "start": 60, "end": 65, "id": 13 }, { "text": "(", "start": 66, "end": 67, "id": 14 }, { "text": "a", "start": 67, "end": 68, "id": 15 }, { "text": ")", "start": 68, "end": 69, "id": 16 }, { "text": "shows", "start": 70, "end": 75, "id": 17 }, { "text": "an", "start": 76, "end": 78, "id": 18 }, { "text": "irregular", "start": 79, "end": 88, "id": 19 }, { "text": "and", "start": 89, "end": 92, "id": 20 }, { "text": "markedly", "start": 93, "end": 101, "id": 21 }, { "text": "hyperintense", "start": 102, "end": 114, "id": 22 }, { "text": "lesion", "start": 115, "end": 121, "id": 23 }, { "text": "(", "start": 122, "end": 123, "id": 24 }, { "text": "arrow", "start": 123, "end": 128, "id": 25 }, { "text": ")", "start": 128, "end": 129, "id": 26 }, { "text": "compared", "start": 130, "end": 138, "id": 27 }, { "text": "with", "start": 139, "end": 143, "id": 28 }, { "text": "fibroglandular", "start": 144, "end": 158, "id": 29 }, { "text": "tissue", "start": 159, "end": 165, "id": 30 }, { "text": ".", "start": 165, "end": 166, "id": 31 }, { "text": "Subtraction", "start": 167, "end": 178, "id": 32 }, { "text": "image", "start": 179, "end": 184, "id": 33 }, { "text": "(", "start": 185, "end": 186, "id": 34 }, { "text": "b", "start": 186, "end": 187, "id": 35 }, { "text": ")", "start": 187, "end": 188, "id": 36 }, { "text": "reveals", "start": 189, "end": 196, "id": 37 }, { "text": "heterogeneous", "start": 197, "end": 210, "id": 38 }, { "text": "enhancement", "start": 211, "end": 222, "id": 39 }, { "text": "(", "start": 223, "end": 224, "id": 40 }, { "text": "arrow", "start": 224, "end": 229, "id": 41 }, { "text": ")", "start": 229, "end": 230, "id": 42 }, { "text": ".", "start": 230, "end": 231, "id": 43 }, { "text": "The", "start": 232, "end": 235, "id": 44 }, { "text": "lesion", "start": 236, "end": 242, "id": 45 }, { "text": "demonstrated", "start": 243, "end": 255, "id": 46 }, { "text": "wash", "start": 256, "end": 260, "id": 47 }, { "text": "-", "start": 260, "end": 261, "id": 48 }, { "text": "out", "start": 261, "end": 264, "id": 49 }, { "text": "kinetic", "start": 265, "end": 272, "id": 50 }, { "text": "(", "start": 273, "end": 274, "id": 51 }, { "text": "not", "start": 274, "end": 277, "id": 52 }, { "text": "shown", "start": 278, "end": 283, "id": 53 }, { "text": ")", "start": 283, "end": 284, "id": 54 }, { "text": ".", "start": 284, "end": 285, "id": 55 }, { "text": "The", "start": 286, "end": 289, "id": 56 }, { "text": "lesion", "start": 290, "end": 296, "id": 57 }, { "text": "was", "start": 297, "end": 300, "id": 58 }, { "text": "categorized", "start": 301, "end": 312, "id": 59 }, { "text": "as", "start": 313, "end": 315, "id": 60 }, { "text": "BI", "start": 316, "end": 318, "id": 61 }, { "text": "-", "start": 318, "end": 319, "id": 62 }, { "text": "RADS", "start": 319, "end": 323, "id": 63 }, { "text": "category", "start": 324, "end": 332, "id": 64 }, { "text": "4c", "start": 333, "end": 335, "id": 65 }, { "text": ".", "start": 335, "end": 336, "id": 66 }, { "text": "Histopathologic", "start": 337, "end": 352, "id": 67 }, { "text": "examination", "start": 353, "end": 364, "id": 68 }, { "text": "(", "start": 365, "end": 366, "id": 69 }, { "text": "c", "start": 366, "end": 367, "id": 70 }, { "text": ",", "start": 367, "end": 368, "id": 71 }, { "text": "H", "start": 369, "end": 370, "id": 72 }, { "text": "-", "start": 370, "end": 371, "id": 73 }, { "text": "E", "start": 371, "end": 372, "id": 74 }, { "text": ",", "start": 372, "end": 373, "id": 75 }, { "text": "×20", "start": 374, "end": 377, "id": 76 }, { "text": ")", "start": 377, "end": 378, "id": 77 }, { "text": "demonstrates", "start": 379, "end": 391, "id": 78 }, { "text": "leaf", "start": 392, "end": 396, "id": 79 }, { "text": "-", "start": 396, "end": 397, "id": 80 }, { "text": "like", "start": 397, "end": 401, "id": 81 }, { "text": "pattern", "start": 402, "end": 409, "id": 82 }, { "text": "consisting", "start": 410, "end": 420, "id": 83 }, { "text": "of", "start": 421, "end": 423, "id": 84 }, { "text": "slits", "start": 424, "end": 429, "id": 85 }, { "text": "lined", "start": 430, "end": 435, "id": 86 }, { "text": "with", "start": 436, "end": 440, "id": 87 }, { "text": "double", "start": 441, "end": 447, "id": 88 }, { "text": "stratified", "start": 448, "end": 458, "id": 89 }, { "text": "epithelium", "start": 459, "end": 469, "id": 90 }, { "text": "(", "start": 470, "end": 471, "id": 91 }, { "text": "arrows", "start": 471, "end": 477, "id": 92 }, { "text": ")", "start": 477, "end": 478, "id": 93 }, { "text": "surrounded", "start": 479, "end": 489, "id": 94 }, { "text": "by", "start": 490, "end": 492, "id": 95 }, { "text": "stromal", "start": 493, "end": 500, "id": 96 }, { "text": "proliferation", "start": 501, "end": 514, "id": 97 }, { "text": "and", "start": 515, "end": 518, "id": 98 }, { "text": "(", "start": 519, "end": 520, "id": 99 }, { "text": "d", "start": 520, "end": 521, "id": 100 }, { "text": ",", "start": 521, "end": 522, "id": 101 }, { "text": "H", "start": 523, "end": 524, "id": 102 }, { "text": "-", "start": 524, "end": 525, "id": 103 }, { "text": "E", "start": 525, "end": 526, "id": 104 }, { "text": ",", "start": 526, "end": 527, "id": 105 }, { "text": "×100", "start": 528, "end": 532, "id": 106 }, { "text": ")", "start": 532, "end": 533, "id": 107 }, { "text": "increased", "start": 534, "end": 543, "id": 108 }, { "text": "number", "start": 544, "end": 550, "id": 109 }, { "text": "of", "start": 551, "end": 553, "id": 110 }, { "text": "atypical", "start": 554, "end": 562, "id": 111 }, { "text": "mitosis", "start": 563, "end": 570, "id": 112 }, { "text": "(", "start": 571, "end": 572, "id": 113 }, { "text": "arrows", "start": 572, "end": 578, "id": 114 }, { "text": ")", "start": 578, "end": 579, "id": 115 }, { "text": "of", "start": 580, "end": 582, "id": 116 }, { "text": "malignant", "start": 583, "end": 592, "id": 117 }, { "text": "phylloid", "start": 593, "end": 601, "id": 118 }, { "text": "tumor", "start": 602, "end": 607, "id": 119 }, { "text": ".", "start": 607, "end": 608, "id": 120 } ]
aaf8727c85e8051bdcc2d011026a13a2b1a882e6
Figure5
5-Figure5-1.png
Figure 5 - A) Coronal T2 WI showing cold abscess and bone marrow edema of the femoral neck (white arrow) in a case of tuberculous arthritis (TB); B) T1 WI post-contrast Fat Sat showing multilocular abscess cavities in a case of TB arthritis (white arrow); C) T1 WI post-contrast Fat Sat showing multilocular abscess cavities in another case of TB arthritis (white arrow); D) Coronal T2 weighted image showing osteomyelitis of the left femoral shaft (white arrow); E) Axial T2 Fat Sat showing left hip septic arthritis with edema and erosions of the femoral head and acetabulum (white arrow).
802
894
{ "a": [ 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32 ], "b": [ 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56 ], "c": [ 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80 ], "d": [ 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98 ], "e": [ 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124 ], "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "2d09d861-950c-4dc5-ae87-b6dcf4b0036f", "label": "a", "points": [ [ 35.5, 306.6 ], [ 35.5, 601.8 ], [ 281.3, 601.8 ], [ 281.3, 306.6 ] ], "color": "yellow" }, { "id": "3299edaa-5902-4dcc-ae18-88326430668e", "label": "b", "points": [ [ 529.6, 306.6 ], [ 529.6, 604.4 ], [ 282.5, 604.4 ], [ 282.5, 306.6 ] ], "color": "cyan" }, { "id": "aad71337-a001-442e-87d1-6c5b077ac29d", "label": "c", "points": [ [ 800.7, 307.9 ], [ 800.7, 605.6 ], [ 532.1, 605.6 ], [ 532.1, 307.9 ] ], "color": "magenta" }, { "id": "7c9839c2-5b86-42dd-84b1-5a6eb59391b5", "label": "d", "points": [ [ 394, 862.8 ], [ 394, 605.6 ], [ 34.2, 605.6 ], [ 34.2, 862.8 ] ], "color": "springgreen" }, { "id": "db4f4720-b566-4f31-a5b9-ccc9986147a2", "label": "e", "points": [ [ 800.7, 864.1 ], [ 800.7, 606.9 ], [ 396.6, 606.9 ], [ 396.6, 864.1 ] ], "color": "tomato" } ]
[ { "text": "Figure", "start": 0, "end": 6, "id": 0 }, { "text": "5", "start": 7, "end": 8, "id": 1 }, { "text": "-", "start": 9, "end": 10, "id": 2 }, { "text": "A", "start": 11, "end": 12, "id": 3 }, { "text": ")", "start": 12, "end": 13, "id": 4 }, { "text": "Coronal", "start": 14, "end": 21, "id": 5 }, { "text": "T2", "start": 22, "end": 24, "id": 6 }, { "text": "WI", "start": 25, "end": 27, "id": 7 }, { "text": "showing", "start": 28, "end": 35, "id": 8 }, { "text": "cold", "start": 36, "end": 40, "id": 9 }, { "text": "abscess", "start": 41, "end": 48, "id": 10 }, { "text": "and", "start": 49, "end": 52, "id": 11 }, { "text": "bone", "start": 53, "end": 57, "id": 12 }, { "text": "marrow", "start": 58, "end": 64, "id": 13 }, { "text": "edema", "start": 65, "end": 70, "id": 14 }, { "text": "of", "start": 71, "end": 73, "id": 15 }, { "text": "the", "start": 74, "end": 77, "id": 16 }, { "text": "femoral", "start": 78, "end": 85, "id": 17 }, { "text": "neck", "start": 86, "end": 90, "id": 18 }, { "text": "(", "start": 91, "end": 92, "id": 19 }, { "text": "white", "start": 92, "end": 97, "id": 20 }, { "text": "arrow", "start": 98, "end": 103, "id": 21 }, { "text": ")", "start": 103, "end": 104, "id": 22 }, { "text": "in", "start": 105, "end": 107, "id": 23 }, { "text": "a", "start": 108, "end": 109, "id": 24 }, { "text": "case", "start": 110, "end": 114, "id": 25 }, { "text": "of", "start": 115, "end": 117, "id": 26 }, { "text": "tuberculous", "start": 118, "end": 129, "id": 27 }, { "text": "arthritis", "start": 130, "end": 139, "id": 28 }, { "text": "(", "start": 140, "end": 141, "id": 29 }, { "text": "TB", "start": 141, "end": 143, "id": 30 }, { "text": ")", "start": 143, "end": 144, "id": 31 }, { "text": ";", "start": 144, "end": 145, "id": 32 }, { "text": "B", "start": 146, "end": 147, "id": 33 }, { "text": ")", "start": 147, "end": 148, "id": 34 }, { "text": "T1", "start": 149, "end": 151, "id": 35 }, { "text": "WI", "start": 152, "end": 154, "id": 36 }, { "text": "post", "start": 155, "end": 159, "id": 37 }, { "text": "-", "start": 159, "end": 160, "id": 38 }, { "text": "contrast", "start": 160, "end": 168, "id": 39 }, { "text": "Fat", "start": 169, "end": 172, "id": 40 }, { "text": "Sat", "start": 173, "end": 176, "id": 41 }, { "text": "showing", "start": 177, "end": 184, "id": 42 }, { "text": "multilocular", "start": 185, "end": 197, "id": 43 }, { "text": "abscess", "start": 198, "end": 205, "id": 44 }, { "text": "cavities", "start": 206, "end": 214, "id": 45 }, { "text": "in", "start": 215, "end": 217, "id": 46 }, { "text": "a", "start": 218, "end": 219, "id": 47 }, { "text": "case", "start": 220, "end": 224, "id": 48 }, { "text": "of", "start": 225, "end": 227, "id": 49 }, { "text": "TB", "start": 228, "end": 230, "id": 50 }, { "text": "arthritis", "start": 231, "end": 240, "id": 51 }, { "text": "(", "start": 241, "end": 242, "id": 52 }, { "text": "white", "start": 242, "end": 247, "id": 53 }, { "text": "arrow", "start": 248, "end": 253, "id": 54 }, { "text": ")", "start": 253, "end": 254, "id": 55 }, { "text": ";", "start": 254, "end": 255, "id": 56 }, { "text": "C", "start": 256, "end": 257, "id": 57 }, { "text": ")", "start": 257, "end": 258, "id": 58 }, { "text": "T1", "start": 259, "end": 261, "id": 59 }, { "text": "WI", "start": 262, "end": 264, "id": 60 }, { "text": "post", "start": 265, "end": 269, "id": 61 }, { "text": "-", "start": 269, "end": 270, "id": 62 }, { "text": "contrast", "start": 270, "end": 278, "id": 63 }, { "text": "Fat", "start": 279, "end": 282, "id": 64 }, { "text": "Sat", "start": 283, "end": 286, "id": 65 }, { "text": "showing", "start": 287, "end": 294, "id": 66 }, { "text": "multilocular", "start": 295, "end": 307, "id": 67 }, { "text": "abscess", "start": 308, "end": 315, "id": 68 }, { "text": "cavities", "start": 316, "end": 324, "id": 69 }, { "text": "in", "start": 325, "end": 327, "id": 70 }, { "text": "another", "start": 328, "end": 335, "id": 71 }, { "text": "case", "start": 336, "end": 340, "id": 72 }, { "text": "of", "start": 341, "end": 343, "id": 73 }, { "text": "TB", "start": 344, "end": 346, "id": 74 }, { "text": "arthritis", "start": 347, "end": 356, "id": 75 }, { "text": "(", "start": 357, "end": 358, "id": 76 }, { "text": "white", "start": 358, "end": 363, "id": 77 }, { "text": "arrow", "start": 364, "end": 369, "id": 78 }, { "text": ")", "start": 369, "end": 370, "id": 79 }, { "text": ";", "start": 370, "end": 371, "id": 80 }, { "text": "D", "start": 372, "end": 373, "id": 81 }, { "text": ")", "start": 373, "end": 374, "id": 82 }, { "text": "Coronal", "start": 375, "end": 382, "id": 83 }, { "text": "T2", "start": 383, "end": 385, "id": 84 }, { "text": "weighted", "start": 386, "end": 394, "id": 85 }, { "text": "image", "start": 395, "end": 400, "id": 86 }, { "text": "showing", "start": 401, "end": 408, "id": 87 }, { "text": "osteomyelitis", "start": 409, "end": 422, "id": 88 }, { "text": "of", "start": 423, "end": 425, "id": 89 }, { "text": "the", "start": 426, "end": 429, "id": 90 }, { "text": "left", "start": 430, "end": 434, "id": 91 }, { "text": "femoral", "start": 435, "end": 442, "id": 92 }, { "text": "shaft", "start": 443, "end": 448, "id": 93 }, { "text": "(", "start": 449, "end": 450, "id": 94 }, { "text": "white", "start": 450, "end": 455, "id": 95 }, { "text": "arrow", "start": 456, "end": 461, "id": 96 }, { "text": ")", "start": 461, "end": 462, "id": 97 }, { "text": ";", "start": 462, "end": 463, "id": 98 }, { "text": "E", "start": 464, "end": 465, "id": 99 }, { "text": ")", "start": 465, "end": 466, "id": 100 }, { "text": "Axial", "start": 467, "end": 472, "id": 101 }, { "text": "T2", "start": 473, "end": 475, "id": 102 }, { "text": "Fat", "start": 476, "end": 479, "id": 103 }, { "text": "Sat", "start": 480, "end": 483, "id": 104 }, { "text": "showing", "start": 484, "end": 491, "id": 105 }, { "text": "left", "start": 492, "end": 496, "id": 106 }, { "text": "hip", "start": 497, "end": 500, "id": 107 }, { "text": "septic", "start": 501, "end": 507, "id": 108 }, { "text": "arthritis", "start": 508, "end": 517, "id": 109 }, { "text": "with", "start": 518, "end": 522, "id": 110 }, { "text": "edema", "start": 523, "end": 528, "id": 111 }, { "text": "and", "start": 529, "end": 532, "id": 112 }, { "text": "erosions", "start": 533, "end": 541, "id": 113 }, { "text": "of", "start": 542, "end": 544, "id": 114 }, { "text": "the", "start": 545, "end": 548, "id": 115 }, { "text": "femoral", "start": 549, "end": 556, "id": 116 }, { "text": "head", "start": 557, "end": 561, "id": 117 }, { "text": "and", "start": 562, "end": 565, "id": 118 }, { "text": "acetabulum", "start": 566, "end": 576, "id": 119 }, { "text": "(", "start": 577, "end": 578, "id": 120 }, { "text": "white", "start": 578, "end": 583, "id": 121 }, { "text": "arrow", "start": 584, "end": 589, "id": 122 }, { "text": ")", "start": 589, "end": 590, "id": 123 }, { "text": ".", "start": 590, "end": 591, "id": 124 } ]
93d0f3a03f07c1b41e2b1f17a3417ea98783db34
Figure4
3-Figure4-1.png
Fig. 4 Imaging study after left antero-lateral approach (revision surgery). a Coronal CT with bone windows: effective foraminal decompression on the left side; note the screws of the arthrodesis which remained untouched. b axial CT: good left-sided decompression; note that the plate does not obstruct the visual axis and the working space
474
1,202
{ "a": [ 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40 ], "b": [ 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64 ], "c": null, "d": null, "e": null, "f": null, "g": null, "h": null, "i": null, "j": null, "k": null, "l": null, "m": null, "n": null, "o": null, "p": null }
[ { "id": "8df184aa-cf8d-44a6-8a72-5606e5673588", "label": "a", "points": [ [ 0.5, 1.8 ], [ 0.5, 743.8 ], [ 473.5, 743.8 ], [ 473.5, 1.8 ] ], "color": "yellow" }, { "id": "ffa7f5a5-b36e-4d6e-b7e8-3507543e581e", "label": "b", "points": [ [ 2.5, 753.3 ], [ 2.5, 1200.3 ], [ 472.5, 1200.3 ], [ 472.5, 753.3 ] ], "color": "cyan" } ]
[ { "text": "Fig", "start": 0, "end": 3, "id": 0 }, { "text": ".", "start": 3, "end": 4, "id": 1 }, { "text": "4", "start": 5, "end": 6, "id": 2 }, { "text": "Imaging", "start": 7, "end": 14, "id": 3 }, { "text": "study", "start": 15, "end": 20, "id": 4 }, { "text": "after", "start": 21, "end": 26, "id": 5 }, { "text": "left", "start": 27, "end": 31, "id": 6 }, { "text": "antero", "start": 32, "end": 38, "id": 7 }, { "text": "-", "start": 38, "end": 39, "id": 8 }, { "text": "lateral", "start": 39, "end": 46, "id": 9 }, { "text": "approach", "start": 47, "end": 55, "id": 10 }, { "text": "(", "start": 56, "end": 57, "id": 11 }, { "text": "revision", "start": 57, "end": 65, "id": 12 }, { "text": "surgery", "start": 66, "end": 73, "id": 13 }, { "text": ")", "start": 73, "end": 74, "id": 14 }, { "text": ".", "start": 74, "end": 75, "id": 15 }, { "text": "a", "start": 76, "end": 77, "id": 16 }, { "text": "Coronal", "start": 78, "end": 85, "id": 17 }, { "text": "CT", "start": 86, "end": 88, "id": 18 }, { "text": "with", "start": 89, "end": 93, "id": 19 }, { "text": "bone", "start": 94, "end": 98, "id": 20 }, { "text": "windows", "start": 99, "end": 106, "id": 21 }, { "text": ":", "start": 106, "end": 107, "id": 22 }, { "text": "effective", "start": 108, "end": 117, "id": 23 }, { "text": "foraminal", "start": 118, "end": 127, "id": 24 }, { "text": "decompression", "start": 128, "end": 141, "id": 25 }, { "text": "on", "start": 142, "end": 144, "id": 26 }, { "text": "the", "start": 145, "end": 148, "id": 27 }, { "text": "left", "start": 149, "end": 153, "id": 28 }, { "text": "side", "start": 154, "end": 158, "id": 29 }, { "text": ";", "start": 158, "end": 159, "id": 30 }, { "text": "note", "start": 160, "end": 164, "id": 31 }, { "text": "the", "start": 165, "end": 168, "id": 32 }, { "text": "screws", "start": 169, "end": 175, "id": 33 }, { "text": "of", "start": 176, "end": 178, "id": 34 }, { "text": "the", "start": 179, "end": 182, "id": 35 }, { "text": "arthrodesis", "start": 183, "end": 194, "id": 36 }, { "text": "which", "start": 195, "end": 200, "id": 37 }, { "text": "remained", "start": 201, "end": 209, "id": 38 }, { "text": "untouched", "start": 210, "end": 219, "id": 39 }, { "text": ".", "start": 219, "end": 220, "id": 40 }, { "text": "b", "start": 221, "end": 222, "id": 41 }, { "text": "axial", "start": 223, "end": 228, "id": 42 }, { "text": "CT", "start": 229, "end": 231, "id": 43 }, { "text": ":", "start": 231, "end": 232, "id": 44 }, { "text": "good", "start": 233, "end": 237, "id": 45 }, { "text": "left", "start": 238, "end": 242, "id": 46 }, { "text": "-", "start": 242, "end": 243, "id": 47 }, { "text": "sided", "start": 243, "end": 248, "id": 48 }, { "text": "decompression", "start": 249, "end": 262, "id": 49 }, { "text": ";", "start": 262, "end": 263, "id": 50 }, { "text": "note", "start": 264, "end": 268, "id": 51 }, { "text": "that", "start": 269, "end": 273, "id": 52 }, { "text": "the", "start": 274, "end": 277, "id": 53 }, { "text": "plate", "start": 278, "end": 283, "id": 54 }, { "text": "does", "start": 284, "end": 288, "id": 55 }, { "text": "not", "start": 289, "end": 292, "id": 56 }, { "text": "obstruct", "start": 293, "end": 301, "id": 57 }, { "text": "the", "start": 302, "end": 305, "id": 58 }, { "text": "visual", "start": 306, "end": 312, "id": 59 }, { "text": "axis", "start": 313, "end": 317, "id": 60 }, { "text": "and", "start": 318, "end": 321, "id": 61 }, { "text": "the", "start": 322, "end": 325, "id": 62 }, { "text": "working", "start": 326, "end": 333, "id": 63 }, { "text": "space", "start": 334, "end": 339, "id": 64 } ]
End of preview.
README.md exists but content is empty. Use the Edit dataset card button to edit it.
Downloads last month
2