Update README.md

README.md

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-Cystic Fibrosis is an autosomal recessive disorder that affects multiple organs. Cystic Fibrosis affects 1 in 2500 newborns in the UK. Cystic Fibrosis affects more than 80,000 individuals globally. Cystic Fibrosis is common in the Caucasian population.
+The ATM protein is a single, high-molecular-weight protein predominantly confined to the nucleus of human fibroblasts, but is present in both nuclear and microsomal fractions from human lymphoblast cells and peripheral blood lymphocytes. ATM protein levels and localization remain constant throughout all stages of the cell cycle. Truncated ATM protein was not detected in lymphoblasts from ataxia-telangiectasia-patients homozygous for mutations leading to premature protein termination. Exposure of normal human cells to gamma-irradiation and the radiomimetic drug neocarzinostatin had no effect on ATM protein levels, in contrast to a noted rise in p53 levels over the same time interval. These findings are consistent with a role for the ATM protein in ensuring the fidelity of DNA repair and cell-cycle regulation following genome damage. 
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