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+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+METHODS/DESIGN : This is a multicentre randomised , double-blind , placebo-controlled feasibility study of glycopyrronium_bromide -LRB- glycopyrrolate -RRB- and hyoscine_hydrobromide -LRB- hyoscine -RRB- in patients with clozapine-induced_hypersalivation .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+The purpose of this study was to investigate the triglyceride-lowering effect of fluvastatin , a new 3-hydroxy-3-methylglutaryl-coenzyme_A _ -LRB- HMG-CoA -RRB- _ reductase inhibitor , in the combined_hyperlipidemia of non-insulin-dependent_diabetes_mellitus -LRB- NIDDM -RRB- .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+In order to evaluate the efficacy of albendazole for the treatment of taeniasis , regimens of 400 mg x 1 day , 800 mg x 2 days , 800 mg x 3 days , 1200 mg x 2 days , and 1200 mg x 3 days were compared .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The objective of this study was to evaluate the efficacy of fluvoxamine in the treatment of pathological_gambling .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Nicotine -LRB- 3x10 -LRB- -5 -RRB- to 3x10 -LRB- -4 -RRB- M -RRB- produced concentration-dependent relaxation on isolated trachea_preparations precontracted by carbachol -LRB- 10 -LRB- -6 -RRB- M -RRB- in both groups .
+The objective of this meta-analysis was to assess the efficacy and safety of tolvaptan in patients with hyponatremia .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : This was a multicenter , open-label , single-arm , long-term phase III study in which patients with FD were given acotiamide , 100 mg t.i.d. , for 48 weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+This indicates that IV PCA and Epidural PCA are equally effective to control the postoperative_pain after VATS lobectomy , which suggests that IV PCA may be used instead of Epidural PCA .
+The efficacy , safety , and tolerance of pentoxifylline -LRB- Trental , Hoechst-Roussel Pharmaceuticals , Inc. -RRB- in the treatment of intermittent_claudication associated with chronic_occlusive_arterial_disease -LRB- COAD -RRB- were evaluated in a double-blind , placebo-controlled , parallel-group , multicenter clinical trial involving a total of 128 outpatients .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+In conclusion , our findings demonstrate that EGCG is effective for growth inhibition of synovial_sarcoma cell lines in vitro and suggest that EGCG may be a new therapeutic option for patients with synovial_sarcoma .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+The objective of this meta-analysis was to assess the efficacy and safety of tolvaptan in patients with hyponatremia .
+OBJECTIVE : The purpose of this study was to evaluate the efficacy and safety of ciclesonide in the treatment of perennial_allergic_rhinitis .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+Aripiprazole in the treatment of patients with borderline_personality_disorder : a double-blind , placebo-controlled study .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+At 2 h after dosing , frovatriptan reduced the risk of nausea by 14 % -LRB- 95 % CI 6-20 % , P = 0.0005 -RRB- , photophobia 17 % -LRB- 95 % CI 12-22 % , P < 0.0001 -RRB- , and phonophobia 14 % -LRB- 95 % CI 17-20 % , P < 0.0001 -RRB- .
+Cinacalcet HCl , an allosteric modulator of the calcium-sensing_receptor -LRB- CaR -RRB- , has recently been approved for the treatment of secondary_hyperparathyroidism in patients with chronic kidney_disease on dialysis , due to its suppressive effect on parathyroid_hormone -LRB- PTH -RRB- secretion .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The present study evaluated whether 2-deoxy-D-glucose -LRB- 2DG , 400 mg/kg -RRB- hyperphagia was affected by methysergide -LRB- 0.5-5 mg/kg -RRB- , ritanserin -LRB- 0.25-2.5 mg/kg -RRB- , or ICS-205,930 -LRB- 0.5-5 mg/kg -RRB- alone or in combination with naltrexone -LRB- 0.25 and 2.5 mg/kg -RRB- .
+A double-blind , placebo-controlled study was performed to assess whether a new calcium antagonist , nisoldipine , in doses of either 5 mg or 10 mg daily , in combination with beta-adrenergic-blocking_drugs -LRB- combination therapy -RRB- was more effective than beta-adrenergic-blocking_drugs alone -LRB- single therapy -RRB- in the treatment of chronic_stable_angina .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+Long-chain omega-3_fatty_acids , eicosapentaenoic_acid -LRB- EPA -RRB- -LRB- 20:5 n-3 -RRB- and docosahexaenoic_acid -LRB- DHA -RRB- -LRB- 22:6 n-3 -RRB- , are associated with decreased triglyceride levels in hypertriglyceridemic patients and decreased risk of developing coronary_heart_disease -LRB- CHD -RRB- .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Comparison of prasugrel and ticagrelor in patients with acute_coronary_syndrome undergoing percutaneous coronary intervention : A meta-analysis of randomized and non-randomized studies .
+Results of a double-blind , randomized , placebo-controlled , parallel study in 37 patients indicate that terfenadine , 60 mg bid , is significantly more effective than placebo and as effective as hydroxyzine , 25 mg qid , in the treatment of chronic_idiopathic_urticaria without causing the somnolence that was associated with the use of hydroxyzine .
+A double-blind , placebo-controlled study was performed to assess whether a new calcium antagonist , nisoldipine , in doses of either 5 mg or 10 mg daily , in combination with beta-adrenergic-blocking_drugs -LRB- combination therapy -RRB- was more effective than beta-adrenergic-blocking_drugs alone -LRB- single therapy -RRB- in the treatment of chronic_stable_angina .
+A binary logistic regression analysis showed that GLU -LRB- odds ratio -LSB- OR -RSB- , 5.052 ; P < 0.01 -RRB- and TC -LRB- OR , 1.074 ; P < 0.01 -RRB- may be risk factors for CP , whereas HDL-c may be a CP protective factor -LRB- OR , 0.833 ; P < 0.01 -RRB- .
+OBJECTIVE : The purpose of this study was to evaluate the efficacy and safety of ciclesonide in the treatment of perennial_allergic_rhinitis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+BACKGROUND : This randomized , double-blind , placebo-controlled trial was designed to assess the efficacy and safety of topiramate in bulimia_nervosa .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+RESULTS : Among 14,090 ACS patients , 7411 -LRB- 52.6 % -RRB- were not on prior ASA or warfarin therapy , 5724 -LRB- 40.6 % -RRB- were on ASA only , 593 -LRB- 4.2 % -RRB- were on warfarin only , and 362 -LRB- 2.6 % -RRB- were on both ASA and warfarin .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A double-blind , randomized , prospective , parallel-group study was conducted to evaluate the efficacy and safety of MTA in the treatment of asthmatic_crisis in children 2 to 6 years of age .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+A multicentre , prospective , randomized , double-blind , parallel group study was undertaken to compare the efficacy and tolerability of topical terbinafine with topical clotrimazole in the treatment of interdigital_tinea_pedis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVES : The aim of the study was to assess the concentrations of interleukin_1b -LRB- IL-1b -RRB- , IL-6 , IL-8 and transforming_growth_factor_b -LRB- TGF-b -RRB- in serum and in bronchoalveolar lavage fluid -LRB- BAL-f -RRB- in COP patients treated with clarithromycin -LRB- CAM -RRB- .
+OBJECTIVE : The purpose of this study was to assess the efficacy of fluvoxamine in the treatment of binge-eating_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+The purpose of this study was to determine the prevalence of low serum insulin-like_growth_factor-I -LRB- IGF-I -RRB- and testosterone in men with poststroke_hemiplegia .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+The efficacy , safety , and tolerance of pentoxifylline -LRB- Trental , Hoechst-Roussel Pharmaceuticals , Inc. -RRB- in the treatment of intermittent_claudication associated with chronic_occlusive_arterial_disease -LRB- COAD -RRB- were evaluated in a double-blind , placebo-controlled , parallel-group , multicenter clinical trial involving a total of 128 outpatients .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+BACKGROUND : Pregabalin is approved by the US Food and Drug Administration for the treatment of fibromyalgia -LRB- FM -RRB- , diabetic_peripheral_neuropathy -LRB- DPN -RRB- , postherpetic_neuralgia -LRB- PHN -RRB- , and neuropathic_pain due to spinal_cord_injury -LRB- SCI -RRB- .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+OBJECTIVE : The purpose of this study was to assess the efficacy of fluvoxamine in the treatment of binge-eating_disorder .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+OBJECTIVE : To compare the efficacy and safety of RimabotulinumtoxinB -LRB- BTX-B -RRB- and OnabotulinumtoxinA -LRB- BTX-A -RRB- in the treatment of masseter_hypertrophy .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+AIM : The aim of this study was to evaluate the effectiveness of short-term -LRB- 3 months -RRB- and long-term -LRB- 12-24 months -RRB- treatment with cabergoline in patients with CD .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+BACKGROUND : To determine the efficacy of fluoxetine in the treatment of social_phobia , fluoxetine was administered to 16 patients with a primary DSM-III-R diagnosis of social_phobia in a 12-week , open , clinical trial .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Efficacy of 3,4-diaminopyridine and pyridostigmine in the treatment of Lambert-Eaton_myasthenic_syndrome : a randomized , double-blind , placebo-controlled , crossover study .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+The purpose of this study was to evaluate the efficacy of sertraline in the treatment of pathological_gambling .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Nintedanib , a small molecule receptor tyrosine kinase inhibitor -LRB- TKI -RRB- of platelet-derived_growth_factor_receptor -LRB- PDGFR -RRB- , fibroblast growth factor receptor -LRB- FGFR -RRB- , and vascular_endothelial_growth_factor_receptor -LRB- VEGFR -RRB- , has been approved for IPF after phase III INPULSIS trials in 2014 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Lopinavir was associated with a decreased risk of DILS -LRB- adjusted hazard ratio = 0.10 , 95 % confidence interval : 0.01 to 0.84 -RRB- , whereas zalcitabine was associated with an increased risk of DILS -LRB- adjusted hazard ratio = 13.7 , 95 % confidence interval : 2.18 to 85.9 -RRB- .
+It has been demonstrated that curcumin has beneficial effects on several ocular_diseases , such as chronic_anterior_uveitis , diabetic_retinopathy , glaucoma , age-related macular_degeneration , and dry_eye_syndrome .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+AAs reduced the risk of SCD in patients with HF by 21 % -LRB- relative risk -LSB- RR -RSB- : 0.79 , 95 % confidence interval -LSB- CI -RSB- : 0.67-0.93 -RRB- .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A double-blind , randomized , prospective , parallel-group study was conducted to evaluate the efficacy and safety of MTA in the treatment of asthmatic_crisis in children 2 to 6 years of age .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+We performed a multicenter , randomized , placebo-controlled , double-blind , phase 3 trial to evaluate the efficacy and safety of prucalopride in children -LRB- 6-18 years old -RRB- with functional constipation .
+In order to evaluate the efficacy of albendazole for the treatment of taeniasis , regimens of 400 mg x 1 day , 800 mg x 2 days , 800 mg x 3 days , 1200 mg x 2 days , and 1200 mg x 3 days were compared .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The aim of this study was to clarify whether ramipril was a therapeutic agent against monocyte_chemoattractant_protein_1 -LRB- MCP-1 -RRB- , interleukin_18 -LRB- IL-18 -RRB- , and interleukin_10 -LRB- IL-10 -RRB- in elderly patients with ACS .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+A double-blind , randomized , prospective , parallel-group study was conducted to evaluate the efficacy and safety of MTA in the treatment of asthmatic_crisis in children 2 to 6 years of age .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+This effect was endothelium-independent and mediated by a histamine_H1_receptor mechanism since it was blocked by the histamine_H1_receptor antagonist , mepyramine -LRB- 10 microM -RRB- , and not by the histamine_H2_receptor antagonist , cimetidine -LRB- 100 microM -RRB- , and since it was mimicked by the histamine_H1_receptor agonist , 2-pyridylethylamine , and not by the histamine_H2_receptor agonist , dimaprit .
+BACKGROUND : The purpose of this study was to assess the efficacy and safety of fluoxetine in the treatment of binge-eating_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+BACKGROUND : This randomized , double-blind , placebo-controlled trial was designed to assess the efficacy and safety of topiramate in bulimia_nervosa .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+AIM : The aim of this study was to evaluate the effectiveness of short-term -LRB- 3 months -RRB- and long-term -LRB- 12-24 months -RRB- treatment with cabergoline in patients with CD .
+The aim of this study was to clarify whether ramipril was a therapeutic agent against monocyte_chemoattractant_protein_1 -LRB- MCP-1 -RRB- , interleukin_18 -LRB- IL-18 -RRB- , and interleukin_10 -LRB- IL-10 -RRB- in elderly patients with ACS .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Comparison of topiroxostat and allopurinol in Japanese hyperuricemic patients with or without gout : a phase 3 , multicentre , randomized , double-blind , double-dummy , active-controlled , parallel-group study .
+BACKGROUND : The purpose of this study was to assess the efficacy and safety of fluoxetine in the treatment of binge-eating_disorder .
+METHODS : This was a multicenter , open-label , single-arm , long-term phase III study in which patients with FD were given acotiamide , 100 mg t.i.d. , for 48 weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+Eight patients with myeloproliferative_disorders , five with polycythaemia rubra vera -LRB- PRV -RRB- and three with essential thrombocythaemia -LRB- ET -RRB- , have been treated with the anti-folate drug Pyrimethamine for periods ranging from 1 to 24 years .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+METHOD : The study was a randomized , double-blind , parallel-group , flexible-dose comparison of sertraline and placebo in outpatients with a DSM-III-R diagnosis of panic_disorder with or without agoraphobia .
+In fact , rivaroxaban has been approved for the prevention of venous_thromboembolism after elective hip or knee replacement surgery , for the prevention and treatment of deep_vein_thrombosis and pulmonary_embolism , for the prevention of stroke in patients with nonvalvular atrial_fibrillation and for the prevention of atherothrombotic events after acute_coronary_syndrome with elevated cardiac biomarkers .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+Mometasone_furoate was as effective as twice-daily beclomethasone_dipropionate or once-daily fluticasone_propionate in the treatment of perennial_allergic_rhinitis , and was as effective as twice-daily beclomethasone_dipropionate and slightly more effective than once-daily oral loratadine in the treatment of seasonal_allergic_rhinitis .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The purpose of this study was to determine the prevalence of low serum insulin-like_growth_factor-I -LRB- IGF-I -RRB- and testosterone in men with poststroke_hemiplegia .
+METHODS : This was a multicenter , open-label , single-arm , long-term phase III study in which patients with FD were given acotiamide , 100 mg t.i.d. , for 48 weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A double-blind , placebo-controlled study was performed to assess whether a new calcium antagonist , nisoldipine , in doses of either 5 mg or 10 mg daily , in combination with beta-adrenergic-blocking_drugs -LRB- combination therapy -RRB- was more effective than beta-adrenergic-blocking_drugs alone -LRB- single therapy -RRB- in the treatment of chronic_stable_angina .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+BACKGROUND : The purpose of this study was to assess the efficacy and safety of fluoxetine in the treatment of binge-eating_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The objective of this meta-analysis was to assess the efficacy and safety of tolvaptan in patients with hyponatremia .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+In order to evaluate the efficacy of albendazole for the treatment of taeniasis , regimens of 400 mg x 1 day , 800 mg x 2 days , 800 mg x 3 days , 1200 mg x 2 days , and 1200 mg x 3 days were compared .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+The aim of this randomized double-blind , placebo-controlled , parallel-group study was to evaluate the efficacy , safety , and tolerability of pregabalin in combination with oxycodone or placebo , in patients with either postherpetic_neuralgia -LRB- PHN -RRB- or painful_diabetic_neuropathy -LRB- PDN -RRB- .
+Compared with non-use , metformin use was associated with a decreased risk of developing severe_dengue -LRB- adjusted risk ratio -LSB- aRR -RSB- = 0.60 , 95 % confidence interval -LSB- CI -RSB- : 0.37-0.98 , P = 0.04 -RRB- .
+RESULTS : Pseudolaric_acid_B inhibited the growth of AGS cells in a time - and dose-dependent manner by arresting the cells at G -LRB- 2 -RRB- / M phase , which was accompanied with a decrease in the levels of cdc2 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+In order to evaluate the efficacy of albendazole for the treatment of taeniasis , regimens of 400 mg x 1 day , 800 mg x 2 days , 800 mg x 3 days , 1200 mg x 2 days , and 1200 mg x 3 days were compared .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+BACKGROUND : This randomized , double-blind , placebo-controlled trial was designed to assess the efficacy and safety of topiramate in bulimia_nervosa .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+Donepezil use in children and adolescents with tics and attention-deficit/hyperactivity _ disorder : an 18-week , single-center , dose-escalating , prospective , open-label study .
+We conducted a pilot study to evaluate the efficacy of topiramate in trigeminal_neuralgia using a randomized , double-blind , placebo-controlled , two-period crossover design .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+Comparison of topiroxostat and allopurinol in Japanese hyperuricemic patients with or without gout : a phase 3 , multicentre , randomized , double-blind , double-dummy , active-controlled , parallel-group study .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We believe this is the first report of successful use of thalidomide in a human being with CRPS 1 , and we therefore recommend that thalidomide should be considered in the treatment of CRPS 1 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVES : An open-label study was performed to assess the efficacy and safety of terbinafine in the treatment of eumycetoma .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : SR_49059 , an orally active , non-peptidic vasopressin_V1a_receptor antagonist , was given orally -LRB- 300 mg once daily -RRB- to 20 patients with RP in a single-centre , double-blind , placebo-controlled , randomized cross-over study with two 7-day periods of treatment separated by 21 days of washout .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+Using in vitro protein tyrosine phosphatase -LRB- PTPase -RRB- assays , we found that sodium_stibogluconate , a drug used in treatment of leishmaniasis , is a potent inhibitor of PTPases Src homology PTPase1 -LRB- SHP-1 -RRB- , SHP-2 , and PTP1B but not the dual-specificity phosphatase mitogen-activated protein kinase phosphatase 1 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+METHODS : Thalidomide was given to 2 patients with EOS -LRB- a 16-year-old girl and an 8-year-old boy -RRB- at an initial dosage of 2 mg/kg/day , and the dosage was increased if necessary .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The aim of this study was to assess the efficacy and safety of azathioprine in the treatment of pulmonary_sarcoidosis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Metaanalysis using a random-effects model , demonstrated that tetracyclines were associated with a decreased risk of CDI -LRB- odds ratio -LSB- OR -RSB- , 0.62 ; 95 % confidence interval -LSB- CI -RSB- , 0.47-0.81 ; P < .001 -RRB- .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+OBJECTIVES : The aim of the study was to assess the concentrations of interleukin_1b -LRB- IL-1b -RRB- , IL-6 , IL-8 and transforming_growth_factor_b -LRB- TGF-b -RRB- in serum and in bronchoalveolar lavage fluid -LRB- BAL-f -RRB- in COP patients treated with clarithromycin -LRB- CAM -RRB- .
+OBJECTIVE : The purpose of this study was to assess the efficacy of fluvoxamine in the treatment of binge-eating_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+BACKGROUND : This randomized , double-blind , placebo-controlled trial was designed to assess the efficacy and safety of topiramate in bulimia_nervosa .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : The purpose of this study was to evaluate the efficacy and safety of ciclesonide in the treatment of perennial_allergic_rhinitis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A phase 2 , randomized , double-blind , placebo-controlled , dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal_candidiasis .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Based on its documented antifungal efficacy and an excellent safety profile , caspofungin has been approved recently by the US Food and Drug Administration for the treatment of invasive_aspergillosis in patients who are refractory to or intolerant of other therapies -LRB- i.e. , amphotericin_B , lipid formulations of amphotericin_B , and/or itraconazole -RRB- .
+Eighty-one FD patients were treated with acotiamide -LRB- 300 mg/day -RRB- -LRB- n = 35 -RRB- , acotiamide -LRB- 300 mg/day -RRB- and rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 28 -RRB- , or rabeprazole -LRB- 10 mg/day -RRB- -LRB- n = 18 -RRB- for a period of 4 weeks and followed after 4 weeks of no treatment .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : The purpose of this study was to evaluate the efficacy and safety of ciclesonide in the treatment of perennial_allergic_rhinitis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The aim of this study was to assess the efficacy and safety of azathioprine in the treatment of pulmonary_sarcoidosis .
+Results of a double-blind , randomized , placebo-controlled , parallel study in 37 patients indicate that terfenadine , 60 mg bid , is significantly more effective than placebo and as effective as hydroxyzine , 25 mg qid , in the treatment of chronic_idiopathic_urticaria without causing the somnolence that was associated with the use of hydroxyzine .
+METHODS : Seventy patients of pityriasis_rosea were given either azithromycin -LRB- n = 35 -RRB- or placebo -LRB- n = 35 -RRB- and were followed-up at 2 , 4 and 6 weeks .
+Nintedanib , a small molecule receptor tyrosine kinase inhibitor -LRB- TKI -RRB- of platelet-derived_growth_factor_receptor -LRB- PDGFR -RRB- , fibroblast growth factor receptor -LRB- FGFR -RRB- , and vascular_endothelial_growth_factor_receptor -LRB- VEGFR -RRB- , has been approved for IPF after phase III INPULSIS trials in 2014 .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+BACKGROUND : Although tetrabenazine , a drug that depletes presynaptic dopamine by inhibiting vesicular_monoamine_transporter_2 -LRB- VMAT2 -RRB- , was approved by the U.S. Food and Drug Administration in 2008 for the treatment of chorea associated with Huntington 's _ disease -LRB- HD -RRB- , there is a paucity of data on its long-term efficacy and safety .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+The efficacy , safety , and tolerance of pentoxifylline -LRB- Trental , Hoechst-Roussel Pharmaceuticals , Inc. -RRB- in the treatment of intermittent_claudication associated with chronic_occlusive_arterial_disease -LRB- COAD -RRB- were evaluated in a double-blind , placebo-controlled , parallel-group , multicenter clinical trial involving a total of 128 outpatients .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+The aim of this study was to assess the efficacy and safety of azathioprine in the treatment of pulmonary_sarcoidosis .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+Mometasone_furoate was as effective as twice-daily beclomethasone_dipropionate or once-daily fluticasone_propionate in the treatment of perennial_allergic_rhinitis , and was as effective as twice-daily beclomethasone_dipropionate and slightly more effective than once-daily oral loratadine in the treatment of seasonal_allergic_rhinitis .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : To compare the efficacy and safety of celecoxib , a cyclooxygenase-2 -LRB- COX-2 -RRB- inhibitor , with those of naproxen , a nonsteroidal anti-inflammatory drug -LRB- NSAID -RRB- , and placebo in the treatment of osteoarthritis_of_the_knee .
+To evaluate the effectiveness of thalidomide for epistaxis in hereditary_hemorrhagic_telangiectasia -LRB- HHT -RRB- , 7 HHT patients with recurrent epistaxis were treated with thalidomide at an initial dose of 50 mg/d , gradually increasing to 100 mg/d if needed .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We report on a case of a 17-year-old female with systemic_lupus_erythematosus -LRB- SLE -RRB- , with a clinical history of complex partial seizure , who developed a tonicoclonic_crisis after receiving hydroxychloroquine for 2 weeks at a dosage of 200 mg/day -LRB- 5 mg/kg -RRB- .
+METHODS : Seventy patients of pityriasis_rosea were given either azithromycin -LRB- n = 35 -RRB- or placebo -LRB- n = 35 -RRB- and were followed-up at 2 , 4 and 6 weeks .
+BACKGROUND : Pregabalin is approved by the US Food and Drug Administration for the treatment of fibromyalgia -LRB- FM -RRB- , diabetic_peripheral_neuropathy -LRB- DPN -RRB- , postherpetic_neuralgia -LRB- PHN -RRB- , and neuropathic_pain due to spinal_cord_injury -LRB- SCI -RRB- .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+A double-blind , placebo-controlled study was performed to assess whether a new calcium antagonist , nisoldipine , in doses of either 5 mg or 10 mg daily , in combination with beta-adrenergic-blocking_drugs -LRB- combination therapy -RRB- was more effective than beta-adrenergic-blocking_drugs alone -LRB- single therapy -RRB- in the treatment of chronic_stable_angina .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Comparison of topiroxostat and allopurinol in Japanese hyperuricemic patients with or without gout : a phase 3 , multicentre , randomized , double-blind , double-dummy , active-controlled , parallel-group study .
+To our knowledge , this is the first report of secnidazole being used in the treatment of dientamoebiasis .
+OBJECTIVE : The aim of this double-blind , placebo-controlled study was to evaluate the efficacy and tolerability of ziprasidone in the treatment of adult patients with borderline_personality_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+Effects of pentamidine , a therapeutic drug for Pneumocystis_carinii_pneumonia -LRB- PCP -RRB- in acquired_immunodeficiency_syndrome -LRB- AIDS -RRB- , on specific bindings of -LSB- 3H -RSB- -LRB- + -RRB- -5-methyl-10,11-dihydro-5H - _ dibenzo -LSB- a , d -RSB- cyclohepten-5,11-imine_maleate -LRB- MK-801 -RRB- and -LSB- 3H -RSB- nitrendipine were investigated in crude synaptic membranes -LRB- CSM -RRB- of rat brain .
+BACKGROUND : This randomized , double-blind , placebo-controlled trial was designed to assess the efficacy and safety of topiramate in bulimia_nervosa .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+We undertook a double-blind , randomized , placebo-controlled , cross-over study to investigate the effects of a single dose of formoterol inhaled via Turbuhaler -LRB- 12 micrograms -RRB- and of albuterol inhaled via Turbuhaler -LRB- 200 micrograms -RRB- on airway responsiveness to AMP and histamine in 16 subjects with mild atopic_asthma .
+Health-related quality of life outcomes with prasugrel among medically managed non-ST-segment elevation acute_coronary_syndrome patients : Insights from the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes -LRB- TRILOGY ACS -RRB- trial .
+Nintedanib , a small molecule receptor tyrosine kinase inhibitor -LRB- TKI -RRB- of platelet-derived_growth_factor_receptor -LRB- PDGFR -RRB- , fibroblast growth factor receptor -LRB- FGFR -RRB- , and vascular_endothelial_growth_factor_receptor -LRB- VEGFR -RRB- , has been approved for IPF after phase III INPULSIS trials in 2014 .
+METHODS : We performed a multicenter , randomized , double-blind , placebo-controlled trial to evaluate the efficacy and safety of eprodisate in patients with AA_amyloidosis_and_kidney_involvement .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
+OBJECTIVE : The purpose of this study was to evaluate the efficacy and safety of ciclesonide in the treatment of perennial_allergic_rhinitis .
+A randomized , double-blind , placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic_stress_disorder .
+MATERIALS AND METHODS : Twenty-eight patients with severe VKC were randomly assigned to receive either topical MMC -LRB- 0.01 % -RRB- -LRB- n = 17 -RRB- or distilled water -LRB- n = 11 -RRB- three times daily for a period of two weeks .
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