import requests from pydantic import BaseModel import numpy as np from bs4 import BeautifulSoup import json from ..tool import Tool from typing import List, Optional, Union from tenacity import retry, wait_random_exponential, stop_after_attempt from numpy import dot from numpy.linalg import norm import openai import pickle @retry(wait=wait_random_exponential(min=1, max=20), stop=stop_after_attempt(6)) def generate_response(prompt, token=2500): response = openai.Completion.create( model="text-davinci-003", prompt=prompt, temperature=0.1, max_tokens=min(2500, token), ) return response["choices"][0]["text"] @retry(wait=wait_random_exponential(min=1, max=20), stop=stop_after_attempt(6)) def get_embedding(text: str, model="text-embedding-ada-002"): return openai.Embedding.create(input=[text], model=model)["data"][0]["embedding"] standard = [ "type of study", "purpose", "challenge", "dataset", "task", "design", "method", "backbone", "baseline", "model", "participant", "patient", "intervention", "group", "duration", "measurement", "performance", "result", "conclusion", "safety", ] stan_emb = [] for item in standard: stan_emb.append(np.array(get_embedding(item))) def dense(topic, docs): try: top_emb = np.array(get_embedding(topic)) except Exception as e: return [-1] nm = norm(top_emb) doc_sim = [] for ky in docs.keys(): try: if docs[ky] is None: tmp = [0] * len(top_emb) elif len(docs[ky].split(" ")) > 100: tmp = get_embedding(docs[ky][0]) else: tmp = [0] * len(top_emb) except Exception as e: tmp = [0] * len(top_emb) sim = dot(top_emb, np.array(tmp)) / (nm * norm(np.array(tmp)) + 1e-5) doc_sim.append(sim) doc_sim = np.array(doc_sim) return doc_sim def semantic_query(term, retmax=100): if retmax > 100: print("semantic searching fewer than 100!") retmax = 100 for cnt in range(10): url = ( "https://api.semanticscholar.org/graph/v1/paper/search?query=" + term.replace(" ", "+") + "&limit=" + str(retmax) + "&fields=title,authors,abstract" ) re = requests.get(url) results = json.loads(re.text) docs = {} if "data" in results: break tmp = 0 while tmp < 10000: tmp += 1 if "data" not in results: return docs for item in results["data"]: if item["abstract"] is not None: docs[item["title"]] = item["abstract"] return docs def draw_term(topic): prp = ( """Concatenate the searching keywords (fewer than 5) in the topic with '+'. For example, when given 'experiments about the harmness of using insulin for teenagers to treat diabetes', answer me with 'insulin+harmness+diabetes+teenager'; when given 'The Operational Situation of Bookstores after Digitalization of Reading', answer me with 'bookstore+digitalization'. Topic: """ + topic + ". Give me the answer with no extra words. " ) response = generate_response(prp) terms = response.replace("\n", " ").split("+") st = "" for term in terms[:4]: st += term + "+" print(st) return st[:-1] def initial(topic, term=None, ret=100): if term is None: term = draw_term(topic) docs = semantic_query(term.replace(" ", "+")[:50], ret) sims = dense(topic, docs) return docs, sims def split_question(criteria): prp = """Please decompose the complex query into a series of simple questions. You can refer to these examples: [QUERY] Randomized controlled and controlled clinical trials which evaluated individual education for adults with type 2 diabetes. The intervention was individual face-to-face patient education while control individuals received usual care, routine treatment or group education. Only studies that assessed outcome measures at least six months from baseline were included. [QUESTIONS] ###1 Is a randomised controlled trial (RCT) or a controlled clinical trial conducted in the article? ###2 Does the article compare individual face-to-face patient education versus usual care, routine treatment or group education? ###3 Are the patients in the article adults with type 2 diabetes? ###4 Does the article outcome measure at least six months from baseline? [QUERY] Studies were included if they conduct experiments of comparing graph neural networks with other deep learning models. Performance on molecular datasets is reported. [QUESTIONS] ###1 Does the article conduct experiments of graph neural networks? ###2 Does the article compare different deep learning models? ###3 Does the article report performance on molecular datasets? Now the QUERY is: """ prp += criteria prp += " What are the decomposed QUESTIONS? " response = generate_response(prp) orig = response.strip("\n") # print('Split Questions: '+orig) if orig.find("###") == -1: cnt = 1 while orig.find(str(cnt) + ". ") > -1: orig = orig.replace(str(cnt) + ". ", "###" + str(cnt) + " ") segs = orig.split("###") ques = [] for seg in segs: if len(seg.split(" ")) < 6: continue if seg[0].isdigit() == False: continue ques.append(seg[2:]) return ques def judge(pred): if ( pred.find("No. ") > -1 or pred.find("No, ") > -1 or pred.find("are not") > -1 or pred.find("is not") > -1 or pred.find("does not") > -1 or pred.find("do not") > -1 ): return 0 else: return 1 def check_doc(til, doc, ques): string = "" for idx, que in enumerate(ques): string += str(idx + 1) + ". " + que + " Why? " prp = """Read the following article and answer the questions. [Article] """ prp += til + ". " + doc[:10000] prp += "[Questions] " + string lt = len(prp.split(" ")) response = generate_response(prp, 4000 - 2 * lt) orig = response.strip("\n") # print('Title: ', til, ', Check: ', orig.replace('\n', ' ')) cnt = 2 preds = [] orig = " " + orig.replace("\n", " ") if orig.find(" 1. ") > -1: orig = orig.split(" 1. ")[-1] while orig.find(" " + str(cnt) + ". ") > -1: pred = orig.split(" " + str(cnt) + ". ")[0] preds.append(pred) orig = orig.split(" " + str(cnt) + ". ")[-1] cnt += 1 preds.append(orig) else: preds = [orig] sm = 0 prob = [] for idx, pred in enumerate(preds): if judge(pred): sm += 1 else: if idx < len(ques): prob.append([ques[idx], pred]) sm = float(sm) / float(len(preds)) # print('Score: ', sm) return sm, prob def draw_conclusion(topic, allcon): prp = ( "We want to explore " + topic + ". Read the analysis table for several articles and summarize your conclusion. # Table: " + "\n" + allcon + "\n # Conclusion: " ) lt = len(prp.split(" ")) response = generate_response(prp, 4000 - 2 * lt) print(allcon) print(response) return response.replace("\n", " ") def draw_subtable(pth, topic, docs): fw = open(pth, "w") cnt = 1 for ky in docs.keys(): fw.write("Table #" + str(cnt) + "\n") cnt += 1 prp = ( "We want to explore " + topic + ". Read the following article and list the key elements and values of the experiment into a concise markdown table. Article: " ) prp += ky + ". " + docs[ky] prp += "Table: " lt = len(prp.split(" ")) response = generate_response(prp, 4000 - 2 * lt) fw.write(response.strip("\n")) fw.write("\n") fw.flush() fw.close() def extra_draw(pth, docs, extra_query): fw = open(pth, "w") cnt = 1 for idx, ky in enumerate(docs.keys()): fw.write("Table #" + str(cnt) + "\n") cnt += 1 if extra_query[idx] != "": prp = extra_query[idx] + ky + ". " + docs[ky] prp += "Table: " lt = len(prp.split(" ")) response = generate_response(prp, 4000 - 2 * lt) fw.write(response.strip("\n")) fw.write("\n") fw.flush() fw.close() def deep_reduce(item): tag = 0 item_emb = get_embedding(item.lower()) sims = [] for stan in stan_emb: sims.append( dot(stan, np.array(item_emb)) / (norm(stan) * norm(np.array(item_emb)) + 1e-5) ) sims = np.array(sims) sr = np.argmax(sims) if sims[sr] > 0.85: item = standard[sr] tag = 1 return item, tag def convert(table0): dic = {} table = [] for tab in table0: if tab.find("|") == -1: if len(tab.split(":")) == 2: tab = "| " + tab.split(":")[0] + " | " + tab.split(":")[1] + " |" else: continue if tab.strip(" ")[0] != "|": tab = "|" + tab if tab.strip(" ")[-1] != "|": tab = tab + "|" table.append(tab) if len(table) < 2: return dic segs = table[0].strip("\n").strip(" ")[1:-1].split("|") if len(segs) < 2: return dic tag = 1 for seg in segs: wd, tmptag = deep_reduce(seg) if tmptag == 0: tag = 0 break if tag and len(table) > 2: vals = table[2].strip("\n").strip(" ")[1:-1].split("|") if len(vals) != len(segs): return {} for idx in range(len(segs)): wd, tmptag = deep_reduce(segs[idx]) dic[wd] = vals[idx] return dic for line in table: wds = line.strip("\n").strip(" ")[1:-1].split("|") if len(wds) != 2: continue wd, tmptag = deep_reduce(wds[0]) if tmptag: dic[wd] = wds[1] return dic def combine(tables, tables1=None, crit=None): extra_query = [] if tables1 is not None: if len(tables) != len(tables1): print("error") else: for idx in range(len(tables)): if tables1[idx] is not None: tables[idx].update(tables1[idx]) bigtab = {} kys = [] for tab in tables: kys += list(tab.keys()) kys = set(kys) if crit is not None: for jdx, tab in enumerate(tables): prp = "" for ky in kys: if ky not in tab: prp += ky + ", " if prp == "": extra_query.append("") else: ask = ( "We want to explore " + crit + ". Read the following article and list the " + prp[:-2] + " of the trial into a concise markdown table. Article: " ) extra_query.append(ask) for ky in kys: line = " | " for tab in tables: if ky not in tab: line += "N/A" else: line += tab[ky] line += " | " bigtab[ky] = line return bigtab, extra_query def get_table(pth, crit): lines = open(pth).readlines()[1:] tmprec = [] rec = [] for line in lines: if line[:7] == "Table #": rec.append(tmprec) tmprec = [] else: tmprec.append(line.strip("\n")) rec.append(tmprec) dicrec = [] for tab in rec: dicrec.append(convert(tab)) orig_tab, extra = combine(dicrec, crit=crit) return orig_tab, dicrec, extra def final_table(pth, dicrec): lines = open(pth).readlines()[1:] tmprec = [] rec = [] for line in lines: if line[:7] == "Table #": rec.append(tmprec) tmprec = [] else: tmprec.append(line.strip("\n")) rec.append(tmprec) dicrec1 = [] for tab in rec: if len(tab) == 0: dicrec1.append(None) else: dicrec1.append(convert(tab)) final_tab, extra = combine(dicrec, tables1=dicrec1) return final_tab def print_table(tab): allcon = "" kys = list(tab.keys()) if len(kys) == 0: return allcon lt = len(tab[kys[0]].strip(" | ").split("|")) header = " | Elements | " splitter = " | ----- | " for i in range(lt): header += str(i + 1) + " | " splitter += "---------- | " print(header) print(splitter) allcon += header + "\n" allcon += splitter + "\n" for ky in kys: line = " | " + ky + tab[ky] print(line) allcon += line + "\n" return allcon class GetNameResponse(BaseModel): """name list""" names: List[str] class GetStructureResponse(BaseModel): """structure list""" state: int content: Optional[str] = None class GetIDResponse(BaseModel): state: int content: Union[str, List[str]] def build_tool(config) -> Tool: tool = Tool( "Meta Analysis Plugin", description="Analyzing literatures", name_for_model="Meta Analysis", description_for_model="Plugin for searching and analyzing literatures. All input should be a json like {'input': 'some input'}. Please use the provided questions and search step by step.", logo_url="https://your-app-url.com/.well-known/logo.png", contact_email="hello@contact.com", legal_info_url="hello@legal.com", ) QRY = "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/" @tool.get("/search_literature") def search_literature(topic: str, maxnum: int, term: str): """search for the given topic literatures in the database and return the path of literatures file and the number of literatures. the searching term should be key words in the topic (2-5 words). the number of literatures will be less than maxnum (recommend 30)""" topic = topic.replace("AND", "").replace("OR", "") if len(topic) < 4: term = topic else: term = term.replace("AND", "").replace("OR", "") if len(term.split(" ")) > 4: term = None retmax = min(maxnum, 50) if retmax == 1: newdocs, sims = initial(topic, term, 1) else: docs, sims = initial(topic, term) srts = np.argsort(-sims) kys = list(docs.keys()) newdocs = {} for sr in srts: if sims[sr] < 0.72 and len(newdocs) > 0: break if len(newdocs) >= retmax: break newdocs[kys[sr]] = docs[kys[sr]] pickle.dump( newdocs, open("searchdoc_" + topic.replace(" ", "_")[:50] + ".pkl", "wb") ) js = {} js["literature_path"] = "searchdoc_" + topic.replace(" ", "_")[:50] + ".pkl" js["literature_number"] = len(newdocs) return js @tool.get("/split_criteria") def split_criteria(criteria: str): """split the screening requirements in the criteria of the literatures into a series of simple yes/no problems, and return the path of the splitted questions.""" ques = split_question(criteria) np.save("split_ques_" + criteria.replace(" ", "_")[:50] + ".npy", ques) js = { "question number": len(ques), "question_path": "split_ques_" + criteria.replace(" ", "_")[:50] + ".npy", } return js @tool.get("/literature_filter") def literature_filter(concat_path: str): """Check each literatures saved in the literature path according to the questions saved in the question path, and return the literatures that match the requirements. Concat path is the concatenated string of literature path and question path connected with '&&&'.""" if len(concat_path.split("&&&")) != 2: js = { "error": "input path cannot recognize the literature path and the question path. please input 'LITERATURE_PATH&&&QUESTION_PATH'. " } return js liter_pth = concat_path.split("&&&")[0].strip(" ") try: docs = pickle.load(open(liter_pth, "rb")) except Exception as e: js = {"error": "cannot open the given literature path!"} return js ques_pth = concat_path.split("&&&")[1].strip(" ") try: ques = np.load(ques_pth, allow_pickle=True) except Exception as e: js = {"error": "cannot open the given question path!"} return js tmp = [] for ky in docs: sm, prob = check_doc(ky, docs[ky], ques) tmp.append(sm) tmp = np.array(tmp) srts = np.argsort(-tmp) finalrecs = [] kys = list(docs.keys()) for sr in srts: if tmp[sr] < 0.6 and len(finalrecs) > 0: break if len(finalrecs) > 9: break finalrecs.append(kys[sr]) finaldocs = {} for ky in finalrecs: finaldocs[ky] = docs[ky] pickle.dump(finaldocs, open("final_" + liter_pth, "wb")) js = { "number of matched literatures": len(finaldocs), "matched_literature_path": "final_" + liter_pth, } return js @tool.get("/draw_table") def draw_table(literature_path_and_topic: str): """extract the important elements of the literatures recorded in the literature path and return the path of table records. concatenate the literature path and the analysis topic with '&&&' as the input.""" if len(literature_path_and_topic.split("&&&")) != 2: js = { "error": "input path cannot recognize the literature path and the topic. please input 'LITERATURE_PATH&&&TOPIC'. " } return js literature_path, topic = literature_path_and_topic.split("&&&") try: finaldocs = pickle.load(open(literature_path.strip(" "), "rb")) except Exception as e: js = {"error": "cannot open the given literature path!"} return js draw_subtable( "subtable_" + literature_path.strip(" ").strip(".pkl") + ".txt", topic, finaldocs, ) js = {"table_path": "subtable_" + literature_path.strip(".pkl") + ".txt"} return js @tool.get("/combine_table") def combine_table( literature_path: str, table_path: str, topic: str ): # ( table_path_and_topic: str ): """combine several tables recorded in the table path into one comprehensive record table and return. give the literature path, table path and the exploring topic as the input.""" # if len(table_path_and_topic.split('&&&'))!=2: # js = {'error': "input path cannot recognize the table path and the topic. please input 'TABLE_PATH&&&TOPIC'. "} # return js # table_path, topic = table_path_and_topic.split('&&&') try: finaldocs = pickle.load(open(literature_path, "rb")) except Exception as e: js = {"error": "cannot open the given literature path!"} return js orig_tab, dicrec, extra = get_table(table_path.strip(" "), topic) extra_draw("extra_" + table_path.strip(" "), finaldocs, extra) final_tab = final_table("extra_" + table_path.strip(" "), dicrec) allcon = print_table(final_tab) fw = open("big_" + table_path, "w") fw.write(allcon) fw.close() js = {"big table path": "big_" + table_path} return js @tool.get("/generate_summary") def generate_summary(topic: str, table_path: str): """given the exploring topic and the record table path of the literatures, this tool generates a paragraph of summary.""" try: table = open(table_path).read() except Exception as e: js = {"error": "cannot open the table file!"} return js con = draw_conclusion(topic, table) js = {"summary": con} return js @tool.get("/print_literature") def print_literature(literature_path: str, print_num: int): """ given the literature path and number that are required to display, this tool returns the title and abstract of the literature. """ try: docs = pickle.load(open(literature_path, "rb")) except Exception as e: js = {"error": "cannot open the literature file!"} return js try: retmax = max(1, min(5, int(print_num))) except Exception as e: js = {"error": "illegal number of printing!"} return js kys = list(docs.keys())[:retmax] print_docs = [] for ky in kys: print_docs.append({"Title": ky, "Abstract": docs[ky]}) js = {"literature_num": len(print_docs), "content": print_docs} return js @tool.get("/print_tablefile") def print_tablefile(table_path: str): """ given the table file path that are required to display, this tool reads the file and returns the string of the table. """ try: con = open(table_path).read() except Exception as e: js = {"error": "cannot open the table file!"} return js js = {"table string": con} return js return tool