# funNCion

The program funNCion predicts functional effects of pathogenic variants in voltage-gated sodium and calcium channels encoded by the SCN and CACNA1 gene families.
This repository includes the code and files to perform the machine learning based predictions.

Find out more on the bioRxiv version of our manuscript: https://www.biorxiv.org/content/10.1101/671453v1. 
Check out the online tool: http://funNCion.broadinstitute.org.
Find the code/data tables used to perform ancestry conditional site-specific selection here: https://github.com/astheeggeggs/parsel.