text: 但大量的遗传病学研究分析证实SLE是多基因遗传，位于第6对染色体中的多个基因位点与发病有关，尤其是遗传性补体基因缺陷（C<sub>1</sub>r、C<sub>1</sub>s、C<sub>2</sub>及C<sub>4</sub>等早期补体成分缺陷）。
entities.entity: SLE
entities.label: dis
entities.entity: 第6对染色体
entities.label: bod
entities.entity: 遗传性补体基因缺陷
entities.label: dis
entities.entity: C<sub>1</sub>r
entities.label: bod
entities.entity: C<sub>1</sub>s
entities.label: bod
entities.entity: C<sub>2</sub>
entities.label: bod
entities.entity: C<sub>4</sub>
entities.label: bod
entities.entity: C<sub>1</sub>r、C<sub>1</sub>s、C<sub>2</sub>及C<sub>4</sub>等早期补体成分缺陷
entities.label: sym