text: SF-1基因定位于染色体9q33，参与类固醇合成过程中的一些酶的编码基因的转录调节，该因子的缺乏将导致肾上腺和性腺的发育不全DAX-1基因位于Xq21，该基因的突变可造成先天性肾上腺发育不全和低促性腺素功能减退症。
entities.entity: SF-1基因
entities.label: bod
entities.entity: 染色体9q33
entities.label: bod
entities.entity: 类固醇
entities.label: bod
entities.entity: 酶
entities.label: bod
entities.entity: 基因
entities.label: bod
entities.entity: 性腺
entities.label: bod
entities.entity: 肾上腺和性腺的发育不全
entities.label: sym
entities.entity: DAX-1基因
entities.label: bod
entities.entity: Xq21
entities.label: bod
entities.entity: 基因
entities.label: bod
entities.entity: 突变
entities.label: sym
entities.entity: 先天性肾上腺发育不全
entities.label: dis
entities.entity: 低促性腺素功能减退症
entities.label: dis