text: （四）生化指标测定神经烯醇化酶（NSE）、S-100蛋白（S-100）和脑型肌酸磷酸激酶（CK-BB）存在于神经组织的不同部位，HIE后6～72小时外周血和脑脊液中的水平升高，与脑损害呈正相关，可作为HIE早期诊断的标志物。
entities.entity: 生化指标测定
entities.label: pro
entities.entity: 神经烯醇化酶
entities.label: bod
entities.entity: NSE
entities.label: bod
entities.entity: S-100蛋白
entities.label: bod
entities.entity: S-100
entities.label: bod
entities.entity: 脑型肌酸磷酸激酶
entities.label: bod
entities.entity: CK-BB
entities.label: bod
entities.entity: 神经组织
entities.label: bod
entities.entity: HIE
entities.label: dis
entities.entity: 脑损
entities.label: dis
entities.entity: 脑损
entities.label: pro
entities.entity: ，可作
entities.label: dis