text: 4.免疫复合物清除障碍正常人可以通过多种途径清除不断产生的免疫复合物，其中补体途径最为重要，SLE患者因C3</sub>缺乏或红细胞膜上C3</sub>b受体减少，导致巨噬细胞清除机制减弱，是免疫复合物沉积及致病的重要原因。
entities.entity: 免疫复合物清除障碍
entities.label: dis
entities.entity: 补体
entities.label: bod
entities.entity: SLE
entities.label: dis
entities.entity: C3</sub>
entities.label: bod
entities.entity: C3</sub>缺乏
entities.label: sym
entities.entity: 红细胞膜上C3</sub>b受体
entities.label: bod
entities.entity: 红细胞膜上C3</sub>b受体减少
entities.label: sym
entities.entity: 巨噬细胞
entities.label: bod
entities.entity: 巨噬细胞清除机制减弱
entities.label: sym
entities.entity: 免疫复合物沉积
entities.label: sym