text: 【鉴别诊断】（一）单纯性乳房早发育单纯性乳房早发育（prematurethelarche）是女孩不完全性性早熟的特殊表现，起病年龄小，常＜2岁，乳腺仅轻度发育，常呈现周期性变化，不伴生长加速和骨龄提前，血清E2</sub>和FSH的基础值常有轻度增高，GnRH兴奋试验中FSH峰值增高LH不增高乳房发育过早真性或假性性早熟的第一特征，或可能由外源性雌激素所引起。
entities.entity: 单纯性乳房早发育
entities.label: sym
entities.entity: 单纯性乳房早发育
entities.label: sym
entities.entity: prematurethelarche
entities.label: sym
entities.entity: 不完全性性早熟
entities.label: dis
entities.entity: 乳腺
entities.label: bod
entities.entity: 血清E2
entities.label: ite
entities.entity: FSH
entities.label: ite
entities.entity: GnRH兴奋试验
entities.label: ite
entities.entity: FSH
entities.label: ite
entities.entity: FSH峰值增高
entities.label: sym
entities.entity: LH
entities.label: ite
entities.entity: LH不增高
entities.label: sym
entities.entity: 乳房
entities.label: bod
entities.entity: 乳房发育过早
entities.label: sym
entities.entity: 真性或假性性早熟
entities.label: dis
entities.entity: 雌激素
entities.label: bod