text: 2.慢性肉芽肿病（chronicgranulomatous，CGD）为一种少见的原发性吞噬细胞功能缺陷病，编码吞噬细胞还原型辅酶Ⅱ（NAPDH）氧化酶基因缺陷，导致吞噬细胞不能杀灭过氧化物酶阳性细菌和真菌，临床表现以反复发生严重感染以及在反复感染部位形成肉芽肿为特征。
entities.entity: 慢性肉芽肿病
entities.label: dis
entities.entity: chronicgranulomatous
entities.label: dis
entities.entity: CGD
entities.label: dis
entities.entity: 原发性吞噬细胞功能缺陷病
entities.label: dis
entities.entity: 编码吞噬细胞还原型辅酶Ⅱ
entities.label: bod
entities.entity: NAPDH
entities.label: bod
entities.entity: 氧化酶基因缺陷
entities.label: dis
entities.entity: 吞噬细胞
entities.label: bod
entities.entity: 过氧化物酶阳性细菌
entities.label: mic
entities.entity: 真菌
entities.label: mic
entities.entity: 反复发生严重感染
entities.label: dis
entities.entity: 肉芽肿
entities.label: dis