document: Mammogram synthesis using a 3D simulation . II . Evaluation of synthetic mammogram texture We have evaluated a method for synthesizing mammograms by comparing the texture of clinical and synthetic mammograms . The synthesis algorithm is based upon simulations of breast tissue and the mammographic imaging process . Mammogram texture was synthesized by projections of simulated adipose tissue compartments . It was hypothesized that the synthetic and clinical texture have similar properties , assuming that the mammogram texture reflects the 3D tissue distribution . The size of the projected compartments was computed by mathematical morphology . The texture energy and fractal dimension were also computed and analyzed in terms of the distribution of texture features within four different tissue regions in clinical and synthetic mammograms . Comparison of the cumulative distributions of the mean features computed from 95 mammograms showed that the synthetic images simulate the mean features of the texture of clinical mammograms . Correlation of clinical and synthetic texture feature histograms , averaged over all images , showed that the synthetic images can simulate the range of features seen over a large group of mammograms . The best agreement with clinical texture was achieved for simulated compartments with radii of 4-13 .3 mm in predominantly adipose tissue regions , and radii of 2.7-5 .33 and 1.3-2 .7 mm in retroareolar and dense fibroglandular tissue regions , respectively
doc_bio_tags: B I O O B I O O O O O B I I O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B I I O O O O O O O O O O O O O O O O O O O O O B I I O O O O O O O O O O B I O O O O O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O B I O O O O O O O O O O O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B I I I O O
extractive_keyphrases: mammogram synthesis 3d simulation synthetic mammogram texture adipose tissue compartments 3d tissue distribution mathematical morphology fractal dimension cumulative distributions synthetic images dense fibroglandular tissue regions
abstractive_keyphrases: breast tissue simulation retroareolar tissue regions x-ray image acquisition computationally compressed phantom