document: Simulation study of the cardiovascular functional status in hypertensive situation An extended cardiovascular model was established based on our previous work to study the consequences of physiological or pathological changes to the homeostatic functions of the cardiovascular system . To study hemodynamic changes in hypertensive situations , the impacts of cardiovascular parameter variations -LRB- peripheral vascular resistance , arterial vessel wall stiffness and baroreflex gain -RRB- upon hemodynamics and the short-term regulation of the cardiovascular system were investigated . For the purpose of analyzing baroregulation function , the short-term regulation of arterial pressure in response to moderate dynamic exercise for normotensive and hypertensive cases was studied through computer simulation and clinical experiments . The simulation results agree well with clinical data . The results of this work suggest that the model presented in this paper provides a useful tool to investigate the functional status of the cardiovascular system in normal or pathological conditions
doc_bio_tags: O O O O B I I O B I O B I I O O O O O O O O O O O O O O B I O O B I O O O O O O O O O O O O O O O O B I I O B I I O B I I I O B I O O B O O O O O O O O O O O O O O O O O O O O O O O B I O O O B I I O O O O O O O O B I O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O
extractive_keyphrases: extended cardiovascular model pathological changes homeostatic functions cardiovascular functional status hypertensive situation cardiovascular parameter variations peripheral vascular resistance arterial vessel wall stiffness baroreflex gain hemodynamics arterial pressure moderate dynamic exercise computer simulation clinical experiments
abstractive_keyphrases: physiological changes short-term regulation normotensive cases