document: Improved detection of lung nodules by using a temporal subtraction technique The authors evaluated the effect of a temporal subtraction technique for digital chest radiography with regard to the accuracy of detection of lung nodules . Twenty solitary lung nodules smaller than 30 mm in diameter , including 10 lung cancers and 10 benign nodules , were used . The nodules were grouped subjectively according to their subtlety . For nonnodular cases , 20 nodules without perceptible interval changes were selected . All chest radiographs were obtained by using a computed radiographic system , and temporal subtraction images were produced by using a program developed at the University of Chicago . The effect of the temporal subtraction image was evaluated by using an observer performance study , with use of receiver operating characteristic analysis . Observer performance with temporal subtraction images was substantially improved -LRB- A/sub z / = 0.980 and 0.958 -RRB- , as compared with that without temporal subtraction images -LRB- A/sub z / = 0.920 and 0.825 -RRB- for the certified radiologists and radiology residents , respectively . The temporal subtraction technique clearly improved diagnostic accuracy for detecting lung nodules , especially subtle cases . In conclusion , the temporal subtraction technique is useful for improving detection accuracy for peripheral lung nodules on digital chest radiographs
doc_bio_tags: O O O O O O O O B I I O O O O O O O B I I O B I I O O O O O O O O O O O O O O O O O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B I I O O O O O O O O O O O B I I O O O O O O O O O O O O O O B I I O O O O O O O O O O O O O B I O O O O O O O O O O B I O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O O B I O B I O O O O B I I O O O O O O O O O O B I O O O O O B I I O O O O O O O B I I O O O O
extractive_keyphrases: temporal subtraction technique digital chest radiography perceptible interval changes observer performance peripheral lung nodules radiology residents certified radiologists subtle cases university of chicago computed radiographic system 30 mm
abstractive_keyphrases: improved lung nodules detection medical diagnostic imaging