text: Emerging potential mechanisms and predispositions to the neurological manifestations of COVID 19 A spectrum of neurological disease associated with COVID 19 is becoming increasingly apparent However the mechanisms behind these manifestations remain poorly understood significantly hindering their management The present review subsequently attempts to address the evolving molecular cellular and systemic mechanisms of NeuroCOVID which we have classified as the acute and long term neurological effects of COVID 19 We place particular emphasis on cerebrovascular demyelinating and encephalitic presentations which have been reported Several mechanisms are presented especially the involvement of a cytokine storm We explore the genetic and demographic factors that may predispose individuals to NeuroCOVID The increasingly evident long term neurological effects are also presented including the impact of the virus on cognition autonomic function and mental wellbeing which represent an impending burden on already stretched healthcare services We subsequently reinforce the need for cautious surveillance especially for those with predisposing factors with effective clinical phenotyping appropriate investigation and if possible prompt treatment This will be imperative to prevent downstream neurological sequelae including those related to the long COVID phenotypes that are being increasingly recognised 