text: Current advances in transfusion medicine 2020 A critical review of selected topics by the AABB Clinical Transfusion Medicine Committee The AABB Clinical Transfusion Medicine Committee CTMC compiles an annual synopsis of the published literature covering important developments in the field of transfusion medicine TM which has been made available as a manuscript published in Transfusion since 2018 CTMC committee members reviewed original manuscripts including TM related topics published electronically ahead or in print from December 2019 to December 2020 The selection of topics and manuscripts was discussed at committee meetings and chosen based on relevance and originality Next committee members worked in pairs to create a synopsis of each topic which was then reviewed by two additional committee members The first and senior authors of this manuscript assembled the final manuscript Although this synopsis is extensive it is not exhaustive and some papers may have been excluded or missed The following topics are included COVID 19 effects on the blood supply and regulatory landscape COVID convalescent plasma adult transfusion practices whole blood molecular immunohematology pediatric TM cellular therapy and apheresis medicine This synopsis provides easy access to relevant topics and may be useful as an educational tool 