text: A review of pears Pyrus spp ancient functional food for modern times Pears have been world widely used as a sweet and nutritious food and a folk medicine for more than two millennia We conducted a review from ancient literatures to current reports to extract evidence based functions of pears We found that pears have many active compounds e g flavonoids triterpenoids and phenolic acids including arbutin chlorogenic acid malaxinic acid etc Most of researchers agree that the beneficial compounds are concentrated in the peels From various in vitro in vivo and human studies the medicinal functions of pears can be summarized as anti diabetic obese hyperlipidemic inflammatory mutagenic and carcinogenic effects detoxification of xenobiotics respiratory and cardio protective effects and skin whitening effects Therefore pears seem to be even effective for prevention from Covid 19 or PM sub 2 5 sub among high susceptible people with multiple underlying diseases For the current or post Covid 19 era pears have potential for functional food or medicine for both of communicable and non communicable disease 