text: Post COVID pulmonary fibrosis therapeutic efficacy using with mesenchymal stem cells How the lung heals COVID 19 is an acute respiratory infectious disease caused by SARS COV 2 Severe Acute Respiratory Syndrome Coronavirus that has become a global pandemic COVID 19 mainly causes the respiratory complications of Acute Respiratory Distress Syndrome ARDS cytokine storm and severe immune disruptions The assays depict that though people recuperate from COVID 19 there are still symptoms that persists in the body causing discomfort which is the consequence of the viral infection due to severe immune disruptions Upon various difficulties of post COVID 19 the pulmonary fibrosis is the stumbling block in the lungs causing severe damage In this review we have shown the effectiveness and importance of the Hepatocyte Growth Factor HGF secreted by Mesenchymal Stem Cell MSC therapy on selective stoppage of the Transforming Growth Factor Beta TGF β signalling pathway by causing immunomodulatory effects that ameliorate the pulmonary fibrosis through paracrine signalling However more pilot studies have to be carried out to determine the efficacy and outcomes of the re emerging complication 