text: The Use of Electroconvulsive Therapy in Neuropsychiatric Complications of Coronavirus Disease 2019 A Systematic Literature Review and Case Report There is a significant prevalence of new onset neuropsychiatric symptoms NPS some severe and persistent in patients with coronavirus disease 2019 COVID 19 This study reports on the use of electroconvulsive therapy ECT to treat NPS associated with COVID 19 A review of the literature pertaining to the use of ECT in patients with COVID 19 and NPS was performed through PubMed PsycINFO and MEDLINE Search terms included Electroconvulsive Therapy and ECT combined with COVID 19 and Severe Acute Respiratory Syndrome Coronavirus 2 SARS COV 2 In addition we present a case in which ECT was used to achieve complete remission in a patient who developed new onset treatment resistant depression psychosis and catatonia associated with COVID 19 A total of 67 articles were reviewed with 3 selected for inclusion These articles detailed 3 case reports of patients with new onset NPS mania psychosis and suicidality and catatonia that developed in the context of active COVID 19 and were treated successfully with ECT ECT a broad spectrum treatment that has been found to be effective in various NPS independent of etiology is shown in our case report and others to be safe and effective for NPS associated with COVID 19 Although we identified only 3 other cases in the literature we believe that the probable antiinflammatory mechanism of ECT its safety and tolerability and the faster time to symptom remission support the need for more research and increased clinician awareness about this life saving procedure 