text: SARS CoV 2 associated multisystem inflammatory syndrome in children MIS C A single centers experience SARS CoV 2 related multisystem inflammatory syndrome in children MIS C is a newly defined clinical entity in pediatric ages resembles Kawasaki Disease or toxic shock syndrome Here we aimed to raise awareness about this SARS CoV 2 related syndrome Children diagnosed with MIS C and followed in Pediatric Clinic between November 2020 and January 2021 were included in study Data about patients demographic characteristics clinical and laboratory findings treatment and outcomes were collected from medical records The median age of 20 children with MIS C was 80 5 months 11 of them were male The most common symptoms at admission were fever 100 abdominal pain 70 myalgia 50 and rash 50 Lymphopenia elevated inflammatory markers and cardiac enzymes were their main laboratory findings Cardiac involvement 90 consisted of myopericarditis valvulitis left ventricular dysfunction and coronary arteritis Symptoms mimicking acute appendicitis and ileus were due to gastrointestinal involvement 50 Macular rash on the trunk erythema on upper eyelids were striking Empiric antibiotics and intravenous immunoglobulin were used in all patients glucocorticoids 90 anti thrombotic 65 and vasoactive 45 agents were used according to severity of disease Response to IVIG treatment was poor whereas glucocorticoids have dramatic affect Seven patients 35 were monitored in intensive care unit none of them required intubation mechanic ventilation or ECMO The median recovery time that is the period when fever subside and inflammatory markers returned to normal was 9 5 days Glucocorticoids has critical role in treatment of MIS C early recognition and treatment may decrease need for intensive care by providing rapid recovery 