text: From asymptomatic to critical illness different clinical manifestations of COVID 19 in Children The global pandemic infectious disease that was named the new coronavirus disease COVID 19 spread throughout the world causing a major public health emergency The causative virus of COVID 19 called SARS CoV 2 can infect all age groups Various clinical signs and symptoms have been observed in neonates children and adolescents during the COVID 19 outbreak The clinical manifestations of COVID 19 might be different due to the medical conditions and comorbid status in elderly and pediatric patients The rise in cases among children has been reported during the COVID 19 pandemic Although infected children generally appear to be asymptomatic or have only mild symptoms COVID 19 in children may also involve a wide spectrum of clinical manifestations ranging from asymptomatic carriers to life threatening and fatal disease as COVID 19 is a systemic disease that can affect multiple organs Due to the lack of knowledge in the current literature it is necessary to describe the atypical clinical features including extrapulmonary manifestations in pediatric patients with COVID 19 This review is conducted to identify knowledge gaps regarding the broad spectrum of clinical signs and symptoms of children with COVID 19 