text: Acute and post acute neurological manifestations of COVID 19 present findings critical appraisal and future directions Acute and post acute neurological symptoms signs and diagnoses have been documented in an increasing number of patients infected by the Severe Acute Respiratory Syndrome Coronavirus 2 SARS CoV 2 which causes Coronavirus Disease 2019 COVID 19 In this review we aimed to summarize the current literature addressing neurological events following SARS CoV 2 infection discuss limitations in the existing literature and suggest future directions that would strengthen our understanding of the neurological sequelae of COVID 19 The presence of neurological manifestations symptoms signs or diagnoses both at the onset or during SARS CoV 2 infection is associated with a more severe disease as demonstrated by a longer hospital stay higher in hospital death rate or the continued presence of sequelae at discharge Although biological mechanisms have been postulated for these findings evidence based data are still lacking to clearly define the incidence range of characteristics and outcomes of these manifestations particularly in non hospitalized patients In addition data from low and middle income countries are scarce leading to uncertainties in the measure of neurological findings of COVID 19 with reference to geography ethnicity socio cultural settings and health care arrangements As a consequence at present a specific phenotype that would specify a post COVID or long COVID neurological syndrome has not yet been identified 