text: Clinical review of cerebral venous thrombosis in the context of COVID 19 vaccinations Evaluation management and scientific questions Vaccine induced immune mediated thrombocytopenia or VITT is a recent and rare phenomenon of thrombosis with thrombocytopenia frequently including cerebral venous thromboses CVT that has been described following vaccination with adenovirus vaccines ChAdOx1 nCOV 19 AstraZeneca and Ad26 COV2 S Johnson and Johnson Janssen J J The evaluation and management of suspected cases of CVT post COVID 19 vaccination are critical skills for a broad range of healthcare providers A collaborative comprehensive review of literature was conducted among a global group of expert neurologists and hematologists Strategies for rapid evaluation and treatment of the CVT in the context of possible VITT exist including inflammatory marker measurements PF4 assays and non heparin anticoagulation 