text: Review of Ebola virus disease in children how far have we come Ebola virus EBOV causes an extremely contagious viral haemorrhagic fever associated with high mortality While historically children have represented a small number of total cases of Ebolavirus disease EVD in recent outbreaks up to a quarter of cases have been in children They pose unique challenges in clinical management and infection prevention and control In this review of paediatric EVD the epidemiology of past EVD outbreaks with specific focus on children is discussed the clinical manifestations and laboratory findings are described and key developments in clinical management including specific topics such as viral persistence and breastfeeding while considering unique psychosocial and anthropological considerations for paediatric care including of survivors and orphans and the stigma they face are discussed In addition to summarising the literature perspectives based on the authors experience of EVD outbreaks in the Democratic Republic of the Congo DRC are described b Abbreviations b ARDS acute respiratory distress syndrome aOR adjusted odds ratio ALT alanine transferase ALIMA Alliance for International Medical Action AST aspartate transaminase BUN blood urea nitrogen CNS central nervous system CUBE chambre durgence biosécurisée pour épidémie COVID 19 coronavirus disease 2019 C sub t sub cycle threshold DRC Democratic Republic of Congo ETC ebola treatment centre ETU ebola treatment unit EBOV ebola virus EVD ebolavirus disease FEAST fluid expansion as supportive therapy GP glycoprotein IV intravenous MEURI monitored emergency use of unregistered interventions NETEC National Ebola Training and Education Centre NP nucleoprotein ORS oral rehydration solution PALM Pamoja Tulinde Maisha PREVAIL Partnership for Research on Ebola Virus in Liberia PPE personal protective equipment PCR polymerase chain reaction PEP post exposure prophylaxis RDTs rapid diagnostic tests RT reverse transcriptase RNA ribonucleic acid UNICEF United Nations International Childrens Emergency Fund USA United States of America WHO World Health Organization 