text: More than 50 long term effects of COVID 19 a systematic review and meta analysis COVID 19 can involve persistence sequelae and other medical complications that last weeks to months after initial recovery This systematic review and meta analysis aims to identify studies assessing the long term effects of COVID 19 LitCOVID and Embase were searched to identify articles with original data published before the 1st of January 2021 with a minimum of 100 patients For effects reported in two or more studies meta analyses using a random effects model were performed using the MetaXL software to estimate the pooled prevalence with 95 CI PRISMA guidelines were followed A total of 18 251 publications were identified of which 15 met the inclusion criteria The prevalence of 55 long term effects was estimated 21 meta analyses were performed and 47 910 patients were included age 17 87 years The included studies defined long COVID as ranging from 14 to 110 days post viral infection It was estimated that 80 of the infected patients with SARS CoV 2 developed one or more long term symptoms The five most common symptoms were fatigue 58 headache 44 attention disorder 27 hair loss 25 and dyspnea 24 Multi disciplinary teams are crucial to developing preventive measures rehabilitation techniques and clinical management strategies with whole patient perspectives designed to address long COVID 19 care 