text:  Complaints and clinical findings six months after COVID 19 outpatient follow up at the University Medical Center Freiburg Increasing evidence suggests that some patients suffer from persistent symptoms for months after recovery from acute COVID 19 However the clinical phenotype and its pathogenesis remain unclear We here present data on complaints and results of a diagnostic workup of patients presenting to the post COVID clinic at the University Medical Center Freiburg Retrospective data analysis of persistently symptomatic patients presenting to our clinic at least 6 months after onset of acute COVID 19 All patients were assessed by a doctor and routine laboratory analysis was carried out Quality of life was assessed using SF 36 questionnaire In case of specific persisting symptoms further organ specific diagnostic evaluation was performed and patients were referred to respective departments specialists 132 Patients 58 male 74 female mean age 53 8 years presented to our clinic at least 6 months after COVID 19 79 60 had been treated as outpatients and 53 40 as inpatients Most common complaints were persistent fatigue 82 and dyspnea on exertion 61 Further common complaints were impairments of concentration 54 insomnia 43 and impairments of smell or taste 35 Quality of life was reduced in all sections of the SF 36 questionnaire yielding a reduced working capacity Significant pathological findings in laboratory echocardiographic and radiological work up were rare Impairments in lung function tests were more common in previously hospitalized patients Patients presenting 6 months after onset of acute COVID 19 suffer from a diverse spectrum of symptoms with impaired quality of life also referred to as Long COVID or Post Acute Sequelae of SARS CoV 2 infection PASC Further research is needed to determine the frequency of these post COVID syndromes and their pathogenesis natural course and treatment options Evaluation and management should be multi disciplinary 