text: Coronavirus Disease 2019 Infection among Children Pathogenesis Treatment and Outcome Coronavirus disease 2019 COVID 19 is a contagious disease that may lead to respiratory distress syndrome and even death Neonates and children are most vulnerable population to COVID 19 infection however the infection is usually milder and has a better prognosis in pediatric patients compared with adults It remains unclear why pediatric population is less symptomatic than adults Children frequently experience respiratory infections and their immune system is in developing stage However large proportion of the asymptomatic pediatric population may contribute to transmission This review explored several aspects of COVID 19 infection such as its epidemiology its molecular pathogenesis with respect to angiotensin converting enzyme 2 receptor and inflammatory mediators intrauterine vertical transmission imaging findings and complications like cytokine release syndrome multisystem inflammatory syndrome in children We also looked at prognostic factors and treatment modalities like corticosteroids RNA replicate inhibitors protease inhibitors Bruton tyrosine kinase inhibitor that is acalabrutinib and convalescent plasma therapy Since there is no strong evidence for the intrauterine transmission early isolation should be performed to protect a neonate from a COVID 19 infected mother Development of vaccine and an effective antiviral drug are the need of the hour 