jarod0411/cm_v6_idx4 · Datasets at Hugging Face

prompt stringlengths 47 229	first_mask_count int64 0 16	first_start_index int64 0 176	first_mask_gen_count int64 1 16	first_mask_tokens stringlengths 0 16	first_mask_gen_count_real int64 0 19	generated_smiles stringlengths 10 199	original_smiles stringlengths 10 192	generated_tokens stringlengths 0 19
<\|startoftext\|><L>CC(C<mask_1:5>(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:5>	1	4	5	)	5	CC(C)(C)C(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	)(C)C
<\|startoftext\|><L>CC(C)(O)c1ccccc1[S@@](=O)c1ccc(<mask_1:1>)cc1<mask_1:1>	2	31	1	Cl	1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(F)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	F
<\|startoftext\|><L>CC(C)(O)c1ccccc1[S@@](=O<mask_1:4>ccc(Cl)cc1<mask_1:4>	3	24	4	)c1	4	CC(C)(O)c1ccccc1[S@@](=O)Cc1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	)Cc1
<\|startoftext\|><L>C<mask_1:4>(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:4>	1	1	4	C	4	C[C@](C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	[C@]
<\|startoftext\|><L><mask_1:4>C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:4>	3	0	4	CC(	4	COC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	COC(
<\|startoftext\|><L>CC(C)(O)c1ccccc1[<mask_1:4>=O)c1ccc(Cl)cc1<mask_1:4>	5	17	4	S@@](	4	CC(C)(O)c1ccccc1[S@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	S@](
<\|startoftext\|><L>C<mask_1:1>C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:1>	2	1	1	C(	1	C(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	(
<\|startoftext\|><L>CC(C)(O)c1ccccc1[S@@](=O)c1<mask_1:2>(Cl)cc1<mask_1:2>	3	27	2	ccc	2	CC(C)(O)c1ccccc1[S@@](=O)c1sc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	sc
<\|startoftext\|><L>CC(C)(O)c1cccc<mask_1:4>S@@](=O)c1ccc(Cl)cc1<mask_1:4>	3	14	4	c1[	4	CC(C)(O)c1ccccc1C[S@@](=O)c1ccc(Cl)cc1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	c1C[
<\|startoftext\|><L>CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)c<mask_1:4>c1<mask_1:4>	0	35	4		4	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)c(Cl)c1	CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1	(Cl)
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C<mask_1:2>H](O)C2)nn1<mask_1:2>	1	40	2	@	2	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	@@
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc<mask_1:5>CC3)[C@H](O)C2)nn1<mask_1:5>	3	31	5	4F)	5	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4C#N)CC3)[C@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	4C#N)
<\|startoftext\|><L>Cc<mask_1:5>2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:5>	6	2	5	1ccc(N	5	Cc1cn(C2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	1cn(C
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[<mask_1:6>(O)C2)nn1<mask_1:6>	4	39	6	C@H]	6	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@](C)(O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	C@](C)
<\|startoftext\|><L>Cc1ccc(N2CC[<mask_1:1>H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:1>	3	12	1	C@@	1	Cc1ccc(N2CC[CH](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	C
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4<mask_1:4>C3)[C@H](O)C2)nn1<mask_1:4>	3	32	4	F)C	4	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4Cl)CC3)[C@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	Cl)C
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC<mask_1:7>H](O)C2)nn1<mask_1:7>	5	36	7	3)[C@	6	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	3)[C@@
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H]<mask_1:4>N(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:4>	5	17	4	(N3CC	4	Cc1ccc(N2CC[C@@H](C3CN(c4ccccc4F)CC3)[C@H](O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	(C3C
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)<mask_1:5>1<mask_1:5>	2	49	5	nn	5	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)c(C)n1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	c(C)n
<\|startoftext\|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC<mask_1:3>(O)C2)nn1<mask_1:3>	7	36	3	3)[C@H]	3	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)C(O)C2)nn1	Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1	3)C
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1CO<mask_1:4>)c1cccc(-c2ccccc2)n1<mask_1:4>	3	22	4	CC2	4	O=C(N=c1[nH][nH]c2c1COCC2O)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	CC2O
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccc<mask_1:5>n1<mask_1:5>	4	39	5	cc2)	5	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cccnc2O)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	nc2O)
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cc<mask_1:4>c2)n1<mask_1:4>	2	38	4	cc	4	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccn(C)c2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	n(C)
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2c<mask_1:5>ccc2)n1<mask_1:5>	1	37	5	c	5	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cc(Cl)ccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	c(Cl)
<\|startoftext\|><L>O=C(<mask_1:6>N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:6>	0	4	6		6	O=C(NC(=O)N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	NC(=O)
<\|startoftext\|><L>O=C(N=c1[nH][nH<mask_1:3>]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:3>	0	15	3		4	O=C(N=c1[nH][nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	][nH
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccc<mask_1:1>2)n1<mask_1:1>	2	39	1	cc	1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cccs2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	s
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2<mask_1:3>C2)c1cccc(-c2ccccc2)n1<mask_1:3>	5	18	3	c1COC	3	O=C(N=c1[nH][nH]c2c1CC2)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	c1C
<\|startoftext\|><L>O=C(N=c1[nH][nH]c2c1COCC<mask_1:3>2)c1cccc(-c2ccccc2)n1<mask_1:3>	0	24	3		3	O=C(N=c1[nH][nH]c2c1COCCNCC2)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	NCC
<\|startoftext\|><L>O=C(N=c1[<mask_1:4>nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:4>	0	9	4		4	O=C(N=c1[nH][nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1	nH][
<\|startoftext\|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C<mask_1:2>1<mask_1:2>	6	33	2	2=O)cc	2	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2)1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	2)
<\|startoftext\|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C<mask_1:2>)cc1<mask_1:2>	3	33	2	2=O	3	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	2=O
<\|startoftext\|><L>COc1ccc(/C=C2\Oc3cc(OC(C)<mask_1:1>c3C2=O)cc1<mask_1:1>	5	25	1	=O)cc	1	COc1ccc(/C=C2\Oc3cc(OC(C))c3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	)
<\|startoftext\|><L>CO<mask_1:5>1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:5>	1	2	5	c	5	COCCCOc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	CCCOc
<\|startoftext\|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3<mask_1:6>2=O)cc1<mask_1:6>	1	32	6	C	6	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C(=O)C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	C(=O)C
<\|startoftext\|><L>COc1ccc(/C=C<mask_1:4>2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:4>	0	12	4		4	COc1ccc(/C=C/[C]2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	/[C]
<\|startoftext\|><L>COc1ccc(/C=C2<mask_1:1>c3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:1>	2	13	1	\O	1	COc1ccc(/C=C2Cc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	C
<\|startoftext\|><L>COc1ccc(/C=C2\Oc3cc(OC(C<mask_1:6>)=O)ccc3C2=O)cc1<mask_1:6>	0	24	6		6	COc1ccc(/C=C2\Oc3cc(OC(C)=CC(N)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	)=CC(N
<\|startoftext\|><L>COc1ccc(/C=C<mask_1:2>2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:2>	0	12	2		2	COc1ccc(/C=C/C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	/C
<\|startoftext\|><L>COc1ccc(<mask_1:3>Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:3>	6	8	3	/C=C2\	3	COc1ccc(N2COc3cc(OC(C)=O)ccc3C2=O)cc1	COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1	N2C
<\|startoftext\|><L>CCn1nccc1C(=O<mask_1:4>H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:4>	5	13	4	)N[C@	4	CCn1nccc1C(=O)N[CH](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	)N[C
<\|startoftext\|><L>CCn1nc<mask_1:6>(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:6>	4	6	6	cc1C	6	CCn1nccc1CNC(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	cc1CNC
<\|startoftext\|><L>CCn1nccc1C(=O)N[C@H](C<mask_1:5>]1C[C@H]2CC[C@H]1C2<mask_1:5>	6	22	5	)[C@@H	5	CCn1nccc1C(=O)N[C@H](C)[C@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	)[C@H
<\|startoftext\|><L>CCn1nccc1C(=O)N<mask_1:5>)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:5>	7	15	5	[C@H](C	5	CCn1nccc1C(=O)NCCN(C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCN(C
<\|startoftext\|><L>CCn1nccc1C<mask_1:2>=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:2>	1	10	2	(	2	CCn1nccc1CC(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	C(
<\|startoftext\|><L>CCn1nccc1C(=O<mask_1:5>[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:5>	2	13	5	)N	5	CCn1nccc1C(=O)N(C)[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	)N(C)
<\|startoftext\|><L>CCn1nccc1C(=O)N[C@H](<mask_1:7>@@H]1C[C@H]2CC[C@H]1C2<mask_1:7>	4	21	7	C)[C	7	CCn1nccc1C(=O)N[C@H](COC)C[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	COC)C[C
<\|startoftext\|><L>CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2C<mask_1:7>@H]1C2<mask_1:7>	3	38	7	C[C	7	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC(=O)[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	C(=O)[C
<\|startoftext\|><L>CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2<mask_1:2>1C2<mask_1:2>	7	37	2	CC[C@H]	2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CC
<\|startoftext\|><L>CC<mask_1:3>1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:3>	1	2	3	n	3	CCCCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2	CCn
<\|startoftext\|><L>C[C@@H](C(=O)O)N1CCN(c2c<mask_1:1>Br)cn2)CC1<mask_1:1>	3	24	1	cc(	1	C[C@@H](C(=O)O)N1CCN(c2c(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	(
<\|startoftext\|><L>C[C@@H](C(=O)O)N1CCN(<mask_1:2>2ccc(Br)cn2)CC1<mask_1:2>	1	21	2	c	2	C[C@@H](C(=O)O)N1CCN(Cc2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	Cc
<\|startoftext\|><L>C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)C<mask_1:5>C1<mask_1:5>	0	35	5		5	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)C(=O)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	(=O)C
<\|startoftext\|><L>C[C@@H](C(=O)O)N1C<mask_1:3>(c2ccc(Br)cn2)CC1<mask_1:3>	2	18	3	CN	3	C[C@@H](C(=O)O)N1CCCN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	CCN
<\|startoftext\|><L>C[C@@H]<mask_1:5>O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:5>	4	7	5	(C(=	5	C[C@@H](CC(=O)O)N1CCN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	(CC(=
<\|startoftext\|><L>C[<mask_1:1>H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:1>	3	2	1	C@@	1	C[CH](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	C
<\|startoftext\|><L>C[C@@H]<mask_1:4>(C(=O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:4>	0	7	4		4	C[C@@H](N)C(C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	(N)C
<\|startoftext\|><L>C[C@@H](C(=O)O)<mask_1:2>N1CCN(c2ccc(Br)cn2)CC1<mask_1:2>	0	15	2		2	C[C@@H](C(=O)O)CCN1CCN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	CC
<\|startoftext\|><L>C[C@@H](C(=O)O)<mask_1:2>CN(c2ccc(Br)cn2)CC1<mask_1:2>	3	15	2	N1C	2	C[C@@H](C(=O)O)N1CN(c2ccc(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	N1
<\|startoftext\|><L>C[C@@H](C(=O)O)N1CCN(c2c<mask_1:4>c(Br)cn2)CC1<mask_1:4>	1	24	4	c	4	C[C@@H](C(=O)O)N1CCN(c2cc(F)c(Br)cn2)CC1	C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1	c(F)
<\|startoftext\|><L>O=C(COCc1cccc(Cl<mask_1:5>N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:5>	4	16	5	)c1)	5	O=C(COCc1cccc(Cl)c1F)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	)c1F)
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)<mask_1:6>@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:6>	3	20	6	N[C	6	O=C(COCc1cccc(Cl)c1)N(C)[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	N(C)[C
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1<mask_1:6>[C@@H](O)C1<mask_1:6>	4	38	6	N1CC	6	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CCOC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	N1CCOC
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@<mask_1:4>C[C@@H]1N1CC[C@@H](O)C1<mask_1:4>	5	25	4	H]1CC	4	O=C(COCc1cccc(Cl)c1)N[C@@H]1CC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	H]1C
<\|startoftext\|><L>O=C(<mask_1:4>cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:4>	5	4	4	COCc1	4	O=C(COc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	COc1
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1<mask_1:3>1CC[C@@H](O)C1<mask_1:3>	1	38	3	N	3	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1NCC1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	NCC
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N<mask_1:7>[C@@H](O)C1<mask_1:7>	3	39	7	1CC	7	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CCC(O)[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	1CCC(O)
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[<mask_1:6>CC[C@@H]1N1CC[C@@H](O)C1<mask_1:6>	7	22	6	C@@H]1C	6	O=C(COCc1cccc(Cl)c1)N[C@H]1CCC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	C@H]1C
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1<mask_1:7>CC[C@@H]1N1CC[C@@H](O)C1<mask_1:7>	1	28	7	C	8	O=C(COCc1cccc(Cl)c1)N[C@@H]1c2ccccc2CC[C@@H]1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	c2ccccc2
<\|startoftext\|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H<mask_1:6>1N1CC[C@@H](O)C1<mask_1:6>	1	36	6	]	6	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H](CO)C1N1CC[C@@H](O)C1	O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1	](CO)C
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(S<mask_1:4>)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>	5	24	4	CC(=O	4	CCCn1c(=O)n(C)c(=O)c2c(SC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	C(=O
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C<mask_1:2>C)C)nc21<mask_1:2>	4	46	2	(C)(	2	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(CC(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	C(
<\|startoftext\|><L>CCCn1c(=O)n<mask_1:3>c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:3>	8	11	3	(C)c(=O)	3	CCCn1c(=O)n(C)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	(C)
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(<mask_1:2>C)C)nc21<mask_1:2>	5	45	2	C(C)(	2	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	C(
<\|startoftext\|><L>CCCn1c(=O)n<mask_1:4>=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>	5	11	4	(C)c(	4	CCCn1c(=O)n(CCC=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	(CCC
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)N<mask_1:4>3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>	1	31	4	c	4	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)N(C)c3cc(C)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	(C)c
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c<mask_1:4>SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>	3	20	4	2c(	4	CCCn1c(=O)n(C)c(=O)c2c(CSCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	2c(C
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc<mask_1:5>n3)nc(C(C)(C)C)nc21<mask_1:5>	4	35	5	(C)o	5	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cccc(C)n3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	cc(C)
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc<mask_1:3>(C)C)nc21<mask_1:3>	5	44	3	(C(C)	3	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(CC(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	(CC
<\|startoftext\|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc<mask_1:7>on3)nc(C(C)(C)C)nc21<mask_1:7>	6	32	7	3cc(C)	7	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(CC)on3)nc(C(C)(C)C)nc21	CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21	3cc(CC)
<\|startoftext\|><L>Cc1cc(CN[C@@H](C)Cn2ccc<mask_1:3>n2)on1<mask_1:3>	0	23	3		3	Cc1cc(CN[C@@H](C)Cn2ccc(C)n2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	(C)
<\|startoftext\|><L>Cc1cc(CN[C@@H]<mask_1:1>n2cccn2)on1<mask_1:1>	4	14	1	(C)C	1	Cc1cc(CN[C@@H]Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	C
<\|startoftext\|><L>Cc1cc<mask_1:4>[C@@H](C)Cn2cccn2)on1<mask_1:4>	3	5	4	(CN	4	Cc1cc(CNC[C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	(CNC
<\|startoftext\|><L>Cc1c<mask_1:4>CN[C@@H](C)Cn2cccn2)on1<mask_1:4>	2	4	4	c(	4	Cc1cc(CCCN[C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	c(CC
<\|startoftext\|><L>Cc1<mask_1:4>CN[C@@H](C)Cn2cccn2)on1<mask_1:4>	3	3	4	cc(	4	Cc1cc(CCN[C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	cc(C
<\|startoftext\|><L>Cc1cc(C<mask_1:3>C@@H](C)Cn2cccn2)on1<mask_1:3>	2	7	3	N[	3	Cc1cc(CNC[C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	NC[
<\|startoftext\|><L>Cc1cc(<mask_1:1>C@@H](C)Cn2cccn2)on1<mask_1:1>	3	6	1	CN[	1	Cc1cc([C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	[
<\|startoftext\|><L>Cc1cc(CN<mask_1:2>H](C)Cn2cccn2)on1<mask_1:2>	4	8	2	[C@@	2	Cc1cc(CN[CH](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	[C
<\|startoftext\|><L>Cc1cc(CN<mask_1:2>C@@H](C)Cn2cccn2)on1<mask_1:2>	1	8	2	[	2	Cc1cc(CNC[C@@H](C)Cn2cccn2)on1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	C[
<\|startoftext\|><L>Cc1cc(CN[C@@H](C)Cn2cccn2)<mask_1:3>1<mask_1:3>	2	26	3	on	3	Cc1cc(CN[C@@H](C)Cn2cccn2)ccn1	Cc1cc(CN[C@@H](C)Cn2cccn2)on1	ccn
<\|startoftext\|><L>COc1ccc(-c2no<mask_1:4>N)c2C(N)=O)cc1<mask_1:4>	2	13	4	c(	4	COc1ccc(-c2noc(CCN)c2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	c(CC
<\|startoftext\|><L>COc1ccc(-c2noc(N<mask_1:1>2C(N)=O)cc1<mask_1:1>	2	16	1	)c	1	COc1ccc(-c2noc(N)2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	)
<\|startoftext\|><L>COc1ccc(-c2no<mask_1:3>N)c2C(N)=O)cc1<mask_1:3>	2	13	3	c(	3	COc1ccc(-c2noc(CN)c2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	c(C
<\|startoftext\|><L>COc1ccc(-c2noc(N)c2C(N)=<mask_1:3>1<mask_1:3>	4	24	3	O)cc	3	COc1ccc(-c2noc(N)c2C(N)=O)s1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	O)s
<\|startoftext\|><L><mask_1:3>ccc(-c2noc(N)c2C(N)=O)cc1<mask_1:3>	4	0	3	COc1	3	Cc1ccc(-c2noc(N)c2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	Cc1
<\|startoftext\|><L>COc1ccc(-c<mask_1:4>c(N)c2C(N)=O)cc1<mask_1:4>	3	10	4	2no	4	COc1ccc(-c2cccc(N)c2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	2ccc
<\|startoftext\|><L>COc1ccc(-c2noc(N)c2C<mask_1:1>O)cc1<mask_1:1>	4	20	1	(N)=	1	COc1ccc(-c2noc(N)c2CCO)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	C
<\|startoftext\|><L>COc1cc<mask_1:4>c2noc(N)c2C(N)=O)cc1<mask_1:4>	3	6	4	c(-	4	COc1ccc(OCc2noc(N)c2C(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	c(OC
<\|startoftext\|><L>COc1ccc(-c2noc(N)c2C(N<mask_1:3>cc1<mask_1:3>	4	22	3	)=O)	3	COc1ccc(-c2noc(N)c2C(N)O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	)O)
<\|startoftext\|><L>COc1ccc(-c2noc(N)c2<mask_1:4>(N)=O)cc1<mask_1:4>	1	19	4	C	4	COc1ccc(-c2noc(N)c2SCCC(N)=O)cc1	COc1ccc(-c2noc(N)c2C(N)=O)cc1	SCCC

<|startoftext|><L>CC(C<mask_1:5>(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:5>

1

4

5

)

5

CC(C)(C)C(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

)(C)C

<|startoftext|><L>CC(C)(O)c1ccccc1[S@@](=O)c1ccc(<mask_1:1>)cc1<mask_1:1>

2

31

1

Cl

1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(F)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

F

<|startoftext|><L>CC(C)(O)c1ccccc1[S@@](=O<mask_1:4>ccc(Cl)cc1<mask_1:4>

3

24

4

)c1

4

CC(C)(O)c1ccccc1[S@@](=O)Cc1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

)Cc1

<|startoftext|><L>C<mask_1:4>(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:4>

1

4

C

4

C[C@](C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

[C@]

<|startoftext|><L><mask_1:4>C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:4>

3

0

4

CC(

4

COC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

COC(

<|startoftext|><L>CC(C)(O)c1ccccc1[<mask_1:4>=O)c1ccc(Cl)cc1<mask_1:4>

5

17

4

S@@](

4

CC(C)(O)c1ccccc1[S@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

S@](

<|startoftext|><L>C<mask_1:1>C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1<mask_1:1>

2

1

C(

1

C(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

(

<|startoftext|><L>CC(C)(O)c1ccccc1[S@@](=O)c1<mask_1:2>(Cl)cc1<mask_1:2>

3

27

2

ccc

2

CC(C)(O)c1ccccc1[S@@](=O)c1sc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

sc

<|startoftext|><L>CC(C)(O)c1cccc<mask_1:4>S@@](=O)c1ccc(Cl)cc1<mask_1:4>

3

14

4

c1[

4

CC(C)(O)c1ccccc1C[S@@](=O)c1ccc(Cl)cc1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

c1C[

<|startoftext|><L>CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)c<mask_1:4>c1<mask_1:4>

0

35

4

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)c(Cl)c1

CC(C)(O)c1ccccc1[S@@](=O)c1ccc(Cl)cc1

(Cl)

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C<mask_1:2>H](O)C2)nn1<mask_1:2>

1

40

2

@

2

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

@@

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc<mask_1:5>CC3)[C@H](O)C2)nn1<mask_1:5>

3

31

5

4F)

5

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4C#N)CC3)[C@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

4C#N)

<|startoftext|><L>Cc<mask_1:5>2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:5>

6

2

5

1ccc(N

5

Cc1cn(C2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

1cn(C

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[<mask_1:6>(O)C2)nn1<mask_1:6>

4

39

6

C@H]

6

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@](C)(O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

C@](C)

<|startoftext|><L>Cc1ccc(N2CC[<mask_1:1>H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:1>

3

12

1

C@@

1

Cc1ccc(N2CC[CH](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

C

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4<mask_1:4>C3)[C@H](O)C2)nn1<mask_1:4>

3

32

4

F)C

4

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4Cl)CC3)[C@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

Cl)C

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC<mask_1:7>H](O)C2)nn1<mask_1:7>

5

36

7

3)[C@

6

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

3)[C@@

<|startoftext|><L>Cc1ccc(N2CC[C@@H]<mask_1:4>N(c4ccccc4F)CC3)[C@H](O)C2)nn1<mask_1:4>

5

17

4

(N3CC

4

Cc1ccc(N2CC[C@@H](C3CN(c4ccccc4F)CC3)[C@H](O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

(C3C

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)<mask_1:5>1<mask_1:5>

2

49

5

nn

5

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)c(C)n1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

c(C)n

<|startoftext|><L>Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC<mask_1:3>(O)C2)nn1<mask_1:3>

7

36

3

3)[C@H]

3

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)C(O)C2)nn1

Cc1ccc(N2CC[C@@H](N3CCN(c4ccccc4F)CC3)[C@H](O)C2)nn1

3)C

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1CO<mask_1:4>)c1cccc(-c2ccccc2)n1<mask_1:4>

3

22

4

CC2

4

O=C(N=c1[nH][nH]c2c1COCC2O)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

CC2O

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccc<mask_1:5>n1<mask_1:5>

4

39

5

cc2)

5

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cccnc2O)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

nc2O)

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cc<mask_1:4>c2)n1<mask_1:4>

2

38

4

cc

4

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccn(C)c2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

n(C)

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2c<mask_1:5>ccc2)n1<mask_1:5>

1

37

5

c

5

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cc(Cl)ccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

c(Cl)

<|startoftext|><L>O=C(<mask_1:6>N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:6>

0

4

6

O=C(NC(=O)N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

NC(=O)

<|startoftext|><L>O=C(N=c1[nH][nH<mask_1:3>]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:3>

0

15

3

4

O=C(N=c1[nH][nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

][nH

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccc<mask_1:1>2)n1<mask_1:1>

2

39

1

cc

1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2cccs2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

s

<|startoftext|><L>O=C(N=c1[nH][nH]c2<mask_1:3>C2)c1cccc(-c2ccccc2)n1<mask_1:3>

5

18

3

c1COC

3

O=C(N=c1[nH][nH]c2c1CC2)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

c1C

<|startoftext|><L>O=C(N=c1[nH][nH]c2c1COCC<mask_1:3>2)c1cccc(-c2ccccc2)n1<mask_1:3>

0

24

3

O=C(N=c1[nH][nH]c2c1COCCNCC2)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

NCC

<|startoftext|><L>O=C(N=c1[<mask_1:4>nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1<mask_1:4>

0

9

4

O=C(N=c1[nH][nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

O=C(N=c1[nH][nH]c2c1COCC2)c1cccc(-c2ccccc2)n1

nH][

<|startoftext|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C<mask_1:2>1<mask_1:2>

6

33

2

2=O)cc

2

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2)1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

2)

<|startoftext|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C<mask_1:2>)cc1<mask_1:2>

3

33

2

2=O

3

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

2=O

<|startoftext|><L>COc1ccc(/C=C2\Oc3cc(OC(C)<mask_1:1>c3C2=O)cc1<mask_1:1>

5

25

1

=O)cc

1

COc1ccc(/C=C2\Oc3cc(OC(C))c3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

)

<|startoftext|><L>CO<mask_1:5>1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:5>

1

2

5

c

5

COCCCOc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

CCCOc

<|startoftext|><L>COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3<mask_1:6>2=O)cc1<mask_1:6>

1

32

6

C

6

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C(=O)C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

C(=O)C

<|startoftext|><L>COc1ccc(/C=C<mask_1:4>2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:4>

0

12

4

COc1ccc(/C=C/[C]2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

/[C]

<|startoftext|><L>COc1ccc(/C=C2<mask_1:1>c3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:1>

2

13

1

\O

1

COc1ccc(/C=C2Cc3cc(OC(C)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

C

<|startoftext|><L>COc1ccc(/C=C2\Oc3cc(OC(C<mask_1:6>)=O)ccc3C2=O)cc1<mask_1:6>

0

24

6

COc1ccc(/C=C2\Oc3cc(OC(C)=CC(N)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

)=CC(N

<|startoftext|><L>COc1ccc(/C=C<mask_1:2>2\Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:2>

0

12

2

COc1ccc(/C=C/C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

/C

<|startoftext|><L>COc1ccc(<mask_1:3>Oc3cc(OC(C)=O)ccc3C2=O)cc1<mask_1:3>

6

8

3

/C=C2\

3

COc1ccc(N2COc3cc(OC(C)=O)ccc3C2=O)cc1

COc1ccc(/C=C2\Oc3cc(OC(C)=O)ccc3C2=O)cc1

N2C

<|startoftext|><L>CCn1nccc1C(=O<mask_1:4>H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:4>

5

13

4

)N[C@

4

CCn1nccc1C(=O)N[CH](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

)N[C

<|startoftext|><L>CCn1nc<mask_1:6>(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:6>

4

6

cc1C

6

CCn1nccc1CNC(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

cc1CNC

<|startoftext|><L>CCn1nccc1C(=O)N[C@H](C<mask_1:5>]1C[C@H]2CC[C@H]1C2<mask_1:5>

6

22

5

)[C@@H

5

CCn1nccc1C(=O)N[C@H](C)[C@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

)[C@H

<|startoftext|><L>CCn1nccc1C(=O)N<mask_1:5>)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:5>

7

15

5

[C@H](C

5

CCn1nccc1C(=O)NCCN(C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCN(C

<|startoftext|><L>CCn1nccc1C<mask_1:2>=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:2>

1

10

2

(

2

CCn1nccc1CC(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

C(

<|startoftext|><L>CCn1nccc1C(=O<mask_1:5>[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:5>

2

13

5

)N

5

CCn1nccc1C(=O)N(C)[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

)N(C)

<|startoftext|><L>CCn1nccc1C(=O)N[C@H](<mask_1:7>@@H]1C[C@H]2CC[C@H]1C2<mask_1:7>

4

21

7

C)[C

7

CCn1nccc1C(=O)N[C@H](COC)C[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

COC)C[C

<|startoftext|><L>CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2C<mask_1:7>@H]1C2<mask_1:7>

3

38

7

C[C

7

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC(=O)[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

C(=O)[C

<|startoftext|><L>CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2<mask_1:2>1C2<mask_1:2>

7

37

2

CC[C@H]

2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CC

<|startoftext|><L>CC<mask_1:3>1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2<mask_1:3>

1

2

3

n

3

CCCCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn1nccc1C(=O)N[C@H](C)[C@@H]1C[C@H]2CC[C@H]1C2

CCn

<|startoftext|><L>C[C@@H](C(=O)O)N1CCN(c2c<mask_1:1>Br)cn2)CC1<mask_1:1>

3

24

1

cc(

1

C[C@@H](C(=O)O)N1CCN(c2c(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

(

<|startoftext|><L>C[C@@H](C(=O)O)N1CCN(<mask_1:2>2ccc(Br)cn2)CC1<mask_1:2>

1

21

2

c

2

C[C@@H](C(=O)O)N1CCN(Cc2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

Cc

<|startoftext|><L>C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)C<mask_1:5>C1<mask_1:5>

0

35

5

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)C(=O)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

(=O)C

<|startoftext|><L>C[C@@H](C(=O)O)N1C<mask_1:3>(c2ccc(Br)cn2)CC1<mask_1:3>

2

18

3

CN

3

C[C@@H](C(=O)O)N1CCCN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

CCN

<|startoftext|><L>C[C@@H]<mask_1:5>O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:5>

4

7

5

(C(=

5

C[C@@H](CC(=O)O)N1CCN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

(CC(=

<|startoftext|><L>C[<mask_1:1>H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:1>

3

2

1

C@@

1

C[CH](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

C

<|startoftext|><L>C[C@@H]<mask_1:4>(C(=O)O)N1CCN(c2ccc(Br)cn2)CC1<mask_1:4>

0

7

4

C[C@@H](N)C(C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

(N)C

<|startoftext|><L>C[C@@H](C(=O)O)<mask_1:2>N1CCN(c2ccc(Br)cn2)CC1<mask_1:2>

0

15

2

C[C@@H](C(=O)O)CCN1CCN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

CC

<|startoftext|><L>C[C@@H](C(=O)O)<mask_1:2>CN(c2ccc(Br)cn2)CC1<mask_1:2>

3

15

2

N1C

2

C[C@@H](C(=O)O)N1CN(c2ccc(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

N1

<|startoftext|><L>C[C@@H](C(=O)O)N1CCN(c2c<mask_1:4>c(Br)cn2)CC1<mask_1:4>

1

24

4

c

4

C[C@@H](C(=O)O)N1CCN(c2cc(F)c(Br)cn2)CC1

C[C@@H](C(=O)O)N1CCN(c2ccc(Br)cn2)CC1

c(F)

<|startoftext|><L>O=C(COCc1cccc(Cl<mask_1:5>N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:5>

4

16

5

)c1)

5

O=C(COCc1cccc(Cl)c1F)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

)c1F)

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)<mask_1:6>@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:6>

3

20

6

N[C

6

O=C(COCc1cccc(Cl)c1)N(C)[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

N(C)[C

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1<mask_1:6>[C@@H](O)C1<mask_1:6>

4

38

6

N1CC

6

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CCOC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

N1CCOC

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@<mask_1:4>C[C@@H]1N1CC[C@@H](O)C1<mask_1:4>

5

25

4

H]1CC

4

O=C(COCc1cccc(Cl)c1)N[C@@H]1CC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

H]1C

<|startoftext|><L>O=C(<mask_1:4>cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1<mask_1:4>

5

4

COCc1

4

O=C(COc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

COc1

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1<mask_1:3>1CC[C@@H](O)C1<mask_1:3>

1

38

3

N

3

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1NCC1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

NCC

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N<mask_1:7>[C@@H](O)C1<mask_1:7>

3

39

7

1CC

7

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CCC(O)[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

1CCC(O)

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[<mask_1:6>CC[C@@H]1N1CC[C@@H](O)C1<mask_1:6>

7

22

6

C@@H]1C

6

O=C(COCc1cccc(Cl)c1)N[C@H]1CCC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

C@H]1C

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1<mask_1:7>CC[C@@H]1N1CC[C@@H](O)C1<mask_1:7>

1

28

7

C

8

O=C(COCc1cccc(Cl)c1)N[C@@H]1c2ccccc2CC[C@@H]1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

c2ccccc2

<|startoftext|><L>O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H<mask_1:6>1N1CC[C@@H](O)C1<mask_1:6>

1

36

6

]

6

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H](CO)C1N1CC[C@@H](O)C1

O=C(COCc1cccc(Cl)c1)N[C@@H]1CCC[C@@H]1N1CC[C@@H](O)C1

](CO)C

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(S<mask_1:4>)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>

5

24

4

CC(=O

4

CCCn1c(=O)n(C)c(=O)c2c(SC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

C(=O

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C<mask_1:2>C)C)nc21<mask_1:2>

4

46

2

(C)(

2

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(CC(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

C(

<|startoftext|><L>CCCn1c(=O)n<mask_1:3>c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:3>

8

11

3

(C)c(=O)

3

CCCn1c(=O)n(C)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

(C)

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(<mask_1:2>C)C)nc21<mask_1:2>

5

45

2

C(C)(

2

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

C(

<|startoftext|><L>CCCn1c(=O)n<mask_1:4>=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>

5

11

4

(C)c(

4

CCCn1c(=O)n(CCC=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

(CCC

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)N<mask_1:4>3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>

1

31

4

c

4

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)N(C)c3cc(C)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

(C)c

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c<mask_1:4>SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21<mask_1:4>

3

20

4

2c(

4

CCCn1c(=O)n(C)c(=O)c2c(CSCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

2c(C

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc<mask_1:5>n3)nc(C(C)(C)C)nc21<mask_1:5>

4

35

5

(C)o

5

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cccc(C)n3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

cc(C)

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc<mask_1:3>(C)C)nc21<mask_1:3>

5

44

3

(C(C)

3

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(CC(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

(CC

<|startoftext|><L>CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc<mask_1:7>on3)nc(C(C)(C)C)nc21<mask_1:7>

6

32

7

3cc(C)

7

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(CC)on3)nc(C(C)(C)C)nc21

CCCn1c(=O)n(C)c(=O)c2c(SCC(=O)Nc3cc(C)on3)nc(C(C)(C)C)nc21

3cc(CC)

<|startoftext|><L>Cc1cc(CN[C@@H](C)Cn2ccc<mask_1:3>n2)on1<mask_1:3>

0

23

3

Cc1cc(CN[C@@H](C)Cn2ccc(C)n2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

(C)

<|startoftext|><L>Cc1cc(CN[C@@H]<mask_1:1>n2cccn2)on1<mask_1:1>

4

14

1

(C)C

1

Cc1cc(CN[C@@H]Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

C

<|startoftext|><L>Cc1cc<mask_1:4>[C@@H](C)Cn2cccn2)on1<mask_1:4>

3

5

4

(CN

4

Cc1cc(CNC[C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

(CNC

<|startoftext|><L>Cc1c<mask_1:4>CN[C@@H](C)Cn2cccn2)on1<mask_1:4>

2

4

c(

4

Cc1cc(CCCN[C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

c(CC

<|startoftext|><L>Cc1<mask_1:4>CN[C@@H](C)Cn2cccn2)on1<mask_1:4>

3

4

cc(

4

Cc1cc(CCN[C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

cc(C

<|startoftext|><L>Cc1cc(C<mask_1:3>C@@H](C)Cn2cccn2)on1<mask_1:3>

2

7

3

N[

3

Cc1cc(CNC[C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

NC[

<|startoftext|><L>Cc1cc(<mask_1:1>C@@H](C)Cn2cccn2)on1<mask_1:1>

3

6

1

CN[

1

Cc1cc([C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

[

<|startoftext|><L>Cc1cc(CN<mask_1:2>H](C)Cn2cccn2)on1<mask_1:2>

4

8

2

[C@@

2

Cc1cc(CN[CH](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

[C

<|startoftext|><L>Cc1cc(CN<mask_1:2>C@@H](C)Cn2cccn2)on1<mask_1:2>

1

8

2

[

2

Cc1cc(CNC[C@@H](C)Cn2cccn2)on1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

C[

<|startoftext|><L>Cc1cc(CN[C@@H](C)Cn2cccn2)<mask_1:3>1<mask_1:3>

2

26

3

on

3

Cc1cc(CN[C@@H](C)Cn2cccn2)ccn1

Cc1cc(CN[C@@H](C)Cn2cccn2)on1

ccn

<|startoftext|><L>COc1ccc(-c2no<mask_1:4>N)c2C(N)=O)cc1<mask_1:4>

2

13

4

c(

4

COc1ccc(-c2noc(CCN)c2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

c(CC

<|startoftext|><L>COc1ccc(-c2noc(N<mask_1:1>2C(N)=O)cc1<mask_1:1>

2

16

1

)c

1

COc1ccc(-c2noc(N)2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

)

<|startoftext|><L>COc1ccc(-c2no<mask_1:3>N)c2C(N)=O)cc1<mask_1:3>

2

13

3

c(

3

COc1ccc(-c2noc(CN)c2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

c(C

<|startoftext|><L>COc1ccc(-c2noc(N)c2C(N)=<mask_1:3>1<mask_1:3>

4

24

3

O)cc

3

COc1ccc(-c2noc(N)c2C(N)=O)s1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

O)s

<|startoftext|><L><mask_1:3>ccc(-c2noc(N)c2C(N)=O)cc1<mask_1:3>

4

0

3

COc1

3

Cc1ccc(-c2noc(N)c2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

Cc1

<|startoftext|><L>COc1ccc(-c<mask_1:4>c(N)c2C(N)=O)cc1<mask_1:4>

3

10

4

2no

4

COc1ccc(-c2cccc(N)c2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

2ccc

<|startoftext|><L>COc1ccc(-c2noc(N)c2C<mask_1:1>O)cc1<mask_1:1>

4

20

1

(N)=

1

COc1ccc(-c2noc(N)c2CCO)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

C

<|startoftext|><L>COc1cc<mask_1:4>c2noc(N)c2C(N)=O)cc1<mask_1:4>

3

6

4

c(-

4

COc1ccc(OCc2noc(N)c2C(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

c(OC

<|startoftext|><L>COc1ccc(-c2noc(N)c2C(N<mask_1:3>cc1<mask_1:3>

4

22

3

)=O)

3

COc1ccc(-c2noc(N)c2C(N)O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

)O)

<|startoftext|><L>COc1ccc(-c2noc(N)c2<mask_1:4>(N)=O)cc1<mask_1:4>

1

19

4

C

4

COc1ccc(-c2noc(N)c2SCCC(N)=O)cc1

COc1ccc(-c2noc(N)c2C(N)=O)cc1

SCCC