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{ |
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"form": [ |
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{ |
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524, |
|
54, |
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176 |
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{ |
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524, |
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54, |
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697, |
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176 |
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], |
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} |
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], |
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"linking": [], |
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"id": 0 |
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}, |
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{ |
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680, |
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672, |
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700, |
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773 |
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{ |
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77, |
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{ |
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[ |
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{ |
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{ |
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} |
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[ |
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24 |
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], |
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[ |
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24 |
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], |
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}, |
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{ |
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|
821, |
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834 |
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], |
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"text": "DATE", |
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{ |
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81, |
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], |
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} |
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], |
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[ |
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4, |
|
25 |
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], |
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[ |
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|
25 |
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], |
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}, |
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{ |
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451, |
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725, |
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745 |
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{ |
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451, |
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725, |
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500, |
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745 |
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} |
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], |
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}, |
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{ |
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583, |
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743 |
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"text": "DIRECTOR", |
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{ |
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583, |
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"text": "DIRECTOR" |
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}, |
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{ |
|
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649, |
|
630, |
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{ |
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649, |
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630, |
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758 |
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], |
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} |
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], |
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}, |
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{ |
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"box": [ |
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|
770, |
|
708, |
|
826 |
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], |
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"text": "", |
|
"label": "answer", |
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{ |
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419, |
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770, |
|
708, |
|
826 |
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], |
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} |
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], |
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"linking": [ |
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[ |
|
26, |
|
8 |
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], |
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[ |
|
26, |
|
8 |
|
] |
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], |
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}, |
|
{ |
|
"text": "FINAL REPORT AMENDMENT", |
|
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|
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|
106, |
|
474, |
|
126 |
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], |
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{ |
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|
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|
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126 |
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}, |
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{ |
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"text": "REPORT", |
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|
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|
108, |
|
382, |
|
123 |
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] |
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}, |
|
{ |
|
"text": "AMENDMENT", |
|
"box": [ |
|
388, |
|
106, |
|
474, |
|
126 |
|
] |
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} |
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], |
|
"id": 9 |
|
}, |
|
{ |
|
"text": "STUDY NAME", |
|
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|
74, |
|
152, |
|
170, |
|
173 |
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], |
|
"linking": [ |
|
[ |
|
10, |
|
11 |
|
], |
|
[ |
|
10, |
|
11 |
|
] |
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], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "STUDY", |
|
"box": [ |
|
74, |
|
152, |
|
123, |
|
173 |
|
] |
|
}, |
|
{ |
|
"text": "NAME", |
|
"box": [ |
|
128, |
|
152, |
|
170, |
|
173 |
|
] |
|
} |
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], |
|
"id": 10 |
|
}, |
|
{ |
|
"text": "Induction of Hepatic Enzymes in rats (B202)", |
|
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|
177, |
|
152, |
|
492, |
|
175 |
|
], |
|
"linking": [ |
|
[ |
|
10, |
|
11 |
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], |
|
[ |
|
10, |
|
11 |
|
] |
|
], |
|
"label": "answer", |
|
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{ |
|
"text": "Induction", |
|
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|
177, |
|
158, |
|
244, |
|
175 |
|
] |
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}, |
|
{ |
|
"text": "of", |
|
"box": [ |
|
250, |
|
154, |
|
267, |
|
174 |
|
] |
|
}, |
|
{ |
|
"text": "Hepatic", |
|
"box": [ |
|
271, |
|
154, |
|
323, |
|
172 |
|
] |
|
}, |
|
{ |
|
"text": "Enzymes", |
|
"box": [ |
|
328, |
|
155, |
|
378, |
|
173 |
|
] |
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}, |
|
{ |
|
"text": "in", |
|
"box": [ |
|
384, |
|
154, |
|
399, |
|
169 |
|
] |
|
}, |
|
{ |
|
"text": "rats", |
|
"box": [ |
|
406, |
|
152, |
|
437, |
|
170 |
|
] |
|
}, |
|
{ |
|
"text": "(B202)", |
|
"box": [ |
|
446, |
|
154, |
|
492, |
|
169 |
|
] |
|
} |
|
], |
|
"id": 11 |
|
}, |
|
{ |
|
"text": "STUDY NUMBER", |
|
"box": [ |
|
77, |
|
182, |
|
187, |
|
204 |
|
], |
|
"linking": [ |
|
[ |
|
12, |
|
13 |
|
], |
|
[ |
|
12, |
|
13 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "STUDY", |
|
"box": [ |
|
77, |
|
186, |
|
126, |
|
204 |
|
] |
|
}, |
|
{ |
|
"text": "NUMBER", |
|
"box": [ |
|
130, |
|
182, |
|
187, |
|
203 |
|
] |
|
} |
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], |
|
"id": 12 |
|
}, |
|
{ |
|
"text": "I- 7016. 401", |
|
"box": [ |
|
191, |
|
183, |
|
264, |
|
203 |
|
], |
|
"linking": [ |
|
[ |
|
12, |
|
13 |
|
], |
|
[ |
|
12, |
|
13 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "I-", |
|
"box": [ |
|
191, |
|
183, |
|
209, |
|
203 |
|
] |
|
}, |
|
{ |
|
"text": "7016.", |
|
"box": [ |
|
209, |
|
184, |
|
243, |
|
202 |
|
] |
|
}, |
|
{ |
|
"text": "401", |
|
"box": [ |
|
243, |
|
186, |
|
264, |
|
200 |
|
] |
|
} |
|
], |
|
"id": 13 |
|
}, |
|
{ |
|
"text": "INITIATION DATE", |
|
"box": [ |
|
80, |
|
215, |
|
215, |
|
233 |
|
], |
|
"linking": [ |
|
[ |
|
14, |
|
15 |
|
], |
|
[ |
|
14, |
|
15 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "INITIATION", |
|
"box": [ |
|
80, |
|
216, |
|
172, |
|
233 |
|
] |
|
}, |
|
{ |
|
"text": "DATE", |
|
"box": [ |
|
177, |
|
215, |
|
215, |
|
230 |
|
] |
|
} |
|
], |
|
"id": 14 |
|
}, |
|
{ |
|
"text": "October 27, 1986", |
|
"box": [ |
|
215, |
|
212, |
|
334, |
|
228 |
|
], |
|
"linking": [ |
|
[ |
|
14, |
|
15 |
|
], |
|
[ |
|
14, |
|
15 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "October", |
|
"box": [ |
|
215, |
|
215, |
|
267, |
|
228 |
|
] |
|
}, |
|
{ |
|
"text": "27,", |
|
"box": [ |
|
271, |
|
212, |
|
295, |
|
227 |
|
] |
|
}, |
|
{ |
|
"text": "1986", |
|
"box": [ |
|
300, |
|
214, |
|
334, |
|
228 |
|
] |
|
} |
|
], |
|
"id": 15 |
|
}, |
|
{ |
|
"text": "DATE OF FINAL REPORT", |
|
"box": [ |
|
359, |
|
211, |
|
542, |
|
231 |
|
], |
|
"linking": [ |
|
[ |
|
16, |
|
17 |
|
], |
|
[ |
|
16, |
|
17 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "DATE", |
|
"box": [ |
|
359, |
|
214, |
|
400, |
|
229 |
|
] |
|
}, |
|
{ |
|
"text": "OF", |
|
"box": [ |
|
406, |
|
211, |
|
427, |
|
231 |
|
] |
|
}, |
|
{ |
|
"text": "FINAL", |
|
"box": [ |
|
434, |
|
214, |
|
483, |
|
229 |
|
] |
|
}, |
|
{ |
|
"text": "REPORT", |
|
"box": [ |
|
489, |
|
212, |
|
542, |
|
230 |
|
] |
|
} |
|
], |
|
"id": 16 |
|
}, |
|
{ |
|
"text": "February 26, 1987", |
|
"box": [ |
|
545, |
|
211, |
|
667, |
|
231 |
|
], |
|
"linking": [ |
|
[ |
|
16, |
|
17 |
|
], |
|
[ |
|
16, |
|
17 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "February", |
|
"box": [ |
|
545, |
|
211, |
|
602, |
|
231 |
|
] |
|
}, |
|
{ |
|
"text": "26,", |
|
"box": [ |
|
609, |
|
212, |
|
631, |
|
229 |
|
] |
|
}, |
|
{ |
|
"text": "1987", |
|
"box": [ |
|
638, |
|
211, |
|
667, |
|
228 |
|
] |
|
} |
|
], |
|
"id": 17 |
|
}, |
|
{ |
|
"text": "PART OF FINAL REPORT TO BE AMENDED (EXACT LOCATION)", |
|
"box": [ |
|
81, |
|
237, |
|
541, |
|
263 |
|
], |
|
"linking": [ |
|
[ |
|
18, |
|
19 |
|
], |
|
[ |
|
18, |
|
19 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "PART", |
|
"box": [ |
|
81, |
|
242, |
|
120, |
|
263 |
|
] |
|
}, |
|
{ |
|
"text": "OF", |
|
"box": [ |
|
126, |
|
244, |
|
146, |
|
262 |
|
] |
|
}, |
|
{ |
|
"text": "FINAL", |
|
"box": [ |
|
152, |
|
244, |
|
201, |
|
262 |
|
] |
|
}, |
|
{ |
|
"text": "REPORT", |
|
"box": [ |
|
205, |
|
246, |
|
262, |
|
260 |
|
] |
|
}, |
|
{ |
|
"text": "TO", |
|
"box": [ |
|
268, |
|
243, |
|
293, |
|
260 |
|
] |
|
}, |
|
{ |
|
"text": "BE", |
|
"box": [ |
|
297, |
|
246, |
|
319, |
|
259 |
|
] |
|
}, |
|
{ |
|
"text": "AMENDED", |
|
"box": [ |
|
321, |
|
242, |
|
389, |
|
259 |
|
] |
|
}, |
|
{ |
|
"text": "(EXACT", |
|
"box": [ |
|
398, |
|
240, |
|
454, |
|
260 |
|
] |
|
}, |
|
{ |
|
"text": "LOCATION)", |
|
"box": [ |
|
459, |
|
237, |
|
541, |
|
259 |
|
] |
|
} |
|
], |
|
"id": 18 |
|
}, |
|
{ |
|
"text": "Page 14 and Table 4", |
|
"box": [ |
|
110, |
|
270, |
|
250, |
|
292 |
|
], |
|
"linking": [ |
|
[ |
|
18, |
|
19 |
|
], |
|
[ |
|
18, |
|
19 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Page", |
|
"box": [ |
|
110, |
|
272, |
|
142, |
|
290 |
|
] |
|
}, |
|
{ |
|
"text": "14", |
|
"box": [ |
|
144, |
|
271, |
|
162, |
|
289 |
|
] |
|
}, |
|
{ |
|
"text": "and", |
|
"box": [ |
|
165, |
|
270, |
|
190, |
|
292 |
|
] |
|
}, |
|
{ |
|
"text": "Table", |
|
"box": [ |
|
193, |
|
271, |
|
232, |
|
289 |
|
] |
|
}, |
|
{ |
|
"text": "4", |
|
"box": [ |
|
233, |
|
272, |
|
250, |
|
287 |
|
] |
|
} |
|
], |
|
"id": 19 |
|
}, |
|
{ |
|
"text": "REASON FOR THE AMENDMENT", |
|
"box": [ |
|
77, |
|
306, |
|
298, |
|
324 |
|
], |
|
"linking": [ |
|
[ |
|
20, |
|
21 |
|
], |
|
[ |
|
20, |
|
21 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "REASON", |
|
"box": [ |
|
77, |
|
306, |
|
137, |
|
323 |
|
] |
|
}, |
|
{ |
|
"text": "FOR", |
|
"box": [ |
|
142, |
|
307, |
|
173, |
|
324 |
|
] |
|
}, |
|
{ |
|
"text": "THE", |
|
"box": [ |
|
177, |
|
306, |
|
208, |
|
321 |
|
] |
|
}, |
|
{ |
|
"text": "AMENDMENT", |
|
"box": [ |
|
216, |
|
306, |
|
298, |
|
324 |
|
] |
|
} |
|
], |
|
"id": 20 |
|
}, |
|
{ |
|
"text": "Request from sponsor", |
|
"box": [ |
|
320, |
|
306, |
|
466, |
|
324 |
|
], |
|
"linking": [ |
|
[ |
|
20, |
|
21 |
|
], |
|
[ |
|
20, |
|
21 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Request", |
|
"box": [ |
|
320, |
|
306, |
|
372, |
|
323 |
|
] |
|
}, |
|
{ |
|
"text": "from", |
|
"box": [ |
|
377, |
|
306, |
|
408, |
|
321 |
|
] |
|
}, |
|
{ |
|
"text": "sponsor", |
|
"box": [ |
|
413, |
|
309, |
|
466, |
|
324 |
|
] |
|
} |
|
], |
|
"id": 21 |
|
}, |
|
{ |
|
"text": "AMENDMENT (Attach additional sheets as necessary)", |
|
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|
81, |
|
455, |
|
524, |
|
477 |
|
], |
|
"linking": [ |
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[ |
|
22, |
|
23 |
|
], |
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[ |
|
22, |
|
23 |
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] |
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], |
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"label": "question", |
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"words": [ |
|
{ |
|
"text": "AMENDMENT", |
|
"box": [ |
|
81, |
|
455, |
|
165, |
|
477 |
|
] |
|
}, |
|
{ |
|
"text": "(Attach", |
|
"box": [ |
|
173, |
|
457, |
|
237, |
|
472 |
|
] |
|
}, |
|
{ |
|
"text": "additional", |
|
"box": [ |
|
243, |
|
455, |
|
334, |
|
470 |
|
] |
|
}, |
|
{ |
|
"text": "sheets", |
|
"box": [ |
|
344, |
|
457, |
|
401, |
|
471 |
|
] |
|
}, |
|
{ |
|
"text": "as", |
|
"box": [ |
|
406, |
|
455, |
|
426, |
|
470 |
|
] |
|
}, |
|
{ |
|
"text": "necessary)", |
|
"box": [ |
|
436, |
|
455, |
|
524, |
|
472 |
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] |
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} |
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], |
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"id": 22 |
|
}, |
|
{ |
|
"text": "see attached", |
|
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|
184, |
|
489, |
|
275, |
|
503 |
|
], |
|
"linking": [ |
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[ |
|
22, |
|
23 |
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], |
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[ |
|
22, |
|
23 |
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] |
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], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "see", |
|
"box": [ |
|
184, |
|
489, |
|
212, |
|
503 |
|
] |
|
}, |
|
{ |
|
"text": "attached", |
|
"box": [ |
|
218, |
|
489, |
|
275, |
|
502 |
|
] |
|
} |
|
], |
|
"id": 23 |
|
}, |
|
{ |
|
"text": "8/ 7/ 87", |
|
"box": [ |
|
102, |
|
698, |
|
186, |
|
744 |
|
], |
|
"linking": [ |
|
[ |
|
2, |
|
24 |
|
], |
|
[ |
|
3, |
|
24 |
|
], |
|
[ |
|
2, |
|
24 |
|
], |
|
[ |
|
3, |
|
24 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "8/", |
|
"box": [ |
|
102, |
|
698, |
|
130, |
|
744 |
|
] |
|
}, |
|
{ |
|
"text": "7/", |
|
"box": [ |
|
128, |
|
698, |
|
156, |
|
744 |
|
] |
|
}, |
|
{ |
|
"text": "87", |
|
"box": [ |
|
161, |
|
705, |
|
186, |
|
736 |
|
] |
|
} |
|
], |
|
"id": 24 |
|
}, |
|
{ |
|
"text": "08/ 14/ 87", |
|
"box": [ |
|
92, |
|
788, |
|
188, |
|
830 |
|
], |
|
"linking": [ |
|
[ |
|
4, |
|
25 |
|
], |
|
[ |
|
4, |
|
25 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "08/", |
|
"box": [ |
|
92, |
|
791, |
|
130, |
|
830 |
|
] |
|
}, |
|
{ |
|
"text": "14/", |
|
"box": [ |
|
133, |
|
788, |
|
158, |
|
823 |
|
] |
|
}, |
|
{ |
|
"text": "87", |
|
"box": [ |
|
163, |
|
791, |
|
188, |
|
820 |
|
] |
|
} |
|
], |
|
"id": 25 |
|
}, |
|
{ |
|
"text": "QUALITY ASSURANCE", |
|
"box": [ |
|
451, |
|
814, |
|
608, |
|
835 |
|
], |
|
"linking": [ |
|
[ |
|
26, |
|
8 |
|
], |
|
[ |
|
26, |
|
8 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "QUALITY", |
|
"box": [ |
|
451, |
|
814, |
|
517, |
|
835 |
|
] |
|
}, |
|
{ |
|
"text": "ASSURANCE", |
|
"box": [ |
|
527, |
|
817, |
|
608, |
|
834 |
|
] |
|
} |
|
], |
|
"id": 26 |
|
} |
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] |
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} |