DOI,instance_id,News Finding,Paper Finding,News Context,Paper Context,scores,field,split,final_score,source,News URL
10.1016/j.robot.2015.01.003,Computer_Science_0,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.","We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment.","If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","One of the most fundamental perceptual notions, space, cannot be an exception to this requirement. We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment. The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs.","[4.0, 3.0, 3.0, 5.0]",Computer_Science,train,3.75,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.compag.2016.07.028,Computer_Science_100,"Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties.","Hyperspectral imaging can be a very powerful tool to phenotype biochemical traits of the whole maize plants, complementing RGB for plant morphological trait analysis.","In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward. Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties. ""How to capture all of these dynamic traits is really a challenging task without these high-throughput systems,"" Ge said.","LWC is successfully predicted with the hyperspectral images for both genotypes (R 2 = 0.81 and 0.92). Hyperspectral imaging can be a very powerful tool to phenotype biochemical traits of the whole maize plants, complementing RGB for plant morphological trait analysis. However, the current rate of increase in yield will not keep pace with this increased demand for food and fuel over the next 35 years .","[4.0, 3.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1177/1080569913501862,Computer_Science_102,"A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region.",One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions.,"But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity. A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","This seems to indicate major generational differences. One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions. As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors.","[4.0, 2.0, 4.0]",Computer_Science,train,3.333333333333333,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_103,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Strong majorities of younger employees (21 to 30 years old) considered checking text messages and emails, answering calls, and even writing text messages and emails as appropriate.","Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.","The divide is perhaps most dramatic in informal meetings (see Figure 2 ). Strong majorities of younger employees (21 to 30 years old) considered checking text messages and emails, answering calls, and even writing text messages and emails as appropriate. On the other hand, strong majorities of employees above 41 years of age consider these actions as inappropriate.","[5.0, 3.0, 5.0, 4.0, 5.0]",Computer_Science,train,4.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_104,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ).","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","In comparison with the posterior hippocampus that had greater grey matter volume compared with control participants, the anterior hippocampus had reduced grey matter volume in taxi drivers (Maguire et al. Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ). We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume.","[4.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.5,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1098/rstb.2008.0288,Computer_Science_105,"With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences.","These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.","This was true even when taxi drivers were compared with another group of navigators, London bus drivers press; see figure 3a,b). While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences. Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al.","[5.0, 4.0, 3.0, 4.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_107,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags. Increased boarding times as a result of baggage fees have financial implications as well.","[4.0, 1.0, 2.0, 2.0]",Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_108,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers.","[4.0, 3.0, 5.0, 4.0]",Computer_Science,train,4.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2552/aabc9b,Computer_Science_113,"Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers.","While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches.","Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects. Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.","We have demonstrated the feasibility of adaptive DBS in PD using a fully implantable device, with feedback control provided by a cortical gamma band oscillation related to the emergence of dyskinesia, a common adverse effect of levodopa therapy and of STN DBS. While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches. The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded.","[4.0, 3.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1287/mnsc.2016.2500,Computer_Science_114,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Ultimately, operations managers need to be involved in the discussions about marketing initiatives such as this one to evaluate the operational impact of marketing initiatives. We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","[3.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_116,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",The same policy may have determined a change in other passengers' behavior in the sense that fewer passengers may have checked a second bag while still flying their preferred airline.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.",We expect that the price-insensitive passengers or those passengers traveling with only one checked bag were indifferent to this policy change. The same policy may have determined a change in other passengers' behavior in the sense that fewer passengers may have checked a second bag while still flying their preferred airline. Another possible explanation is that price-sensitive customers of those airlines that charged for one checked bag started flying Southwest instead.,"[1.0, 2.0, 2.0, 2.0, 4.0]",Computer_Science,train,2.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_117,Higher-income professionals had less tolerance for smartphone use in business meetings.,"In formal meetings, professionals in the West were least accepting of mobile phone use during meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Prior to getting the results, we suspected there might be some variation by region. In formal meetings, professionals in the West were least accepting of mobile phone use during meetings. In informal meetings, professionals in the Southwest were least accepting of mobile phone use.","[4.0, 4.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.8,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_119,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.",This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[2.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1177/1080569913501862,Computer_Science_12,Higher-income professionals had less tolerance for smartphone use in business meetings.,"Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Also, higher-income professionals showed lower acceptance for mobile phone use during meetings. Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings. In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region.","[5.0, 5.0, 2.0, 5.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_120,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","Similar to the one checked bag fee policy, the theory does not offer a clear direction of the impact of the first two checked bags fees policy on departure delays, and hence we let the data dictate the correct hypothesis:","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","That is, we expect an incremental impact of implementing fees for the first two checked bags over implementing fees for only one checked bag. Similar to the one checked bag fee policy, the theory does not offer a clear direction of the impact of the first two checked bags fees policy on departure delays, and hence we let the data dictate the correct hypothesis: Better relative performance as measured by departure delays is achieved when charging for the first two checked bags versus charging only for one checked bag.","[3.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_121,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[4.0, 4.0, 5.0, 3.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_122,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.",We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces.,"This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.",We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition. We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"[2.0, 2.0, 4.0]",Computer_Science,train,2.6666666666666665,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1126/science.aaf2654,Computer_Science_123,"The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.","Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved. For instance, 76 percent of respondents believe it is more moral for an autonomous vehicle, should such a circumstance arise, to sacrifice one passenger rather than 10 pedestrians.","For example, our scenarios did not feature any uncertainty about decision outcomes, but a collective discussion about moral algorithms will have to tackle the concepts of expected risk, expected value, and blame assignment. Such liability considerations will need to accompany existing discussions of regulation [21] , and we hope that psychological studies inspired by our own will be able to inform this discussion. Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.","[4.0, 1.0, 3.0, 4.0]",Computer_Science,train,4.0,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1007/s10055-018-0346-3,Computer_Science_126,The researchers found that people remember information better if it is presented to them in a virtual environment.,"If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.","The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.","[3.0, 5.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.6,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_128,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[3.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/978-3-642-55220-5_1,Computer_Science_13,"Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips, etc.","Although we insist on the case of finite fields of small characteristic, where quasi-polynomial complexity is obtained, our new algorithm improves the complexity of discrete logarithm computations in a much larger range of finite fields.","It discredits several cryptographic systems that until now were assumed to provide sufficient security safeguards. Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips, etc. The algorithm they devised stands out from the best algorithms known to date for this problem.","-The complexity result relies on three key heuristics: the existence of a polynomial representation of the appropriate form; the fact that the smoothness probabilities of some non-uniformly distributed polynomials are similar to the probabilities for uniformly random polynomials of the same degree; and the linear independence of some finite field elements related to the action of PGL 2 (F q ). Although we insist on the case of finite fields of small characteristic, where quasi-polynomial complexity is obtained, our new algorithm improves the complexity of discrete logarithm computations in a much larger range of finite fields. More precisely, in finite fields of the form F q k , where q grows as L q k (α), the complexity becomes L q k (α + o(1)).","[1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.25,news,http://www.homelandsecuritynewswire.com/dr20140518-new-algorithm-revolutionizes-cryptography
10.1007/s10055-018-0346-3,Computer_Science_131,The researchers found that people remember information better if it is presented to them in a virtual environment.,We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces.,"Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.",We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition. We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"[5.0, 3.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1177/1080569913501862,Computer_Science_132,87 percent of people said answering a call was rarely or never acceptable in business meetings.,Roughly 71% of the professionals said they would not make a call or take a call during a meeting.,"Among their findings:

Three out of four people -- 76 percent -- said checking texts or emails was unacceptable behavior in business meetings. 87 percent of people said answering a call was rarely or never acceptable in business meetings. Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate.","Interestingly, just 24% thought using a laptop in a meeting was not appropriate. Roughly 71% of the professionals said they would not make a call or take a call during a meeting. Approximately 63% said that they would not text message during meetings.","[4.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.5,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_133,They found that people remember information better if it is presented to them in a virtual environment.,"If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[4.0, 4.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.4,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/s10055-018-0346-3,Computer_Science_134,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[4.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.5,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.robot.2015.01.003,Computer_Science_135,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent.,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands. Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent. Knowing the number of spatial dimensions is not, however, the same as having the notion of space.","[2.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1186/s12911-017-0526-1,Computer_Science_136,"Their approach can help incorporate other patient-specific factors, such as age and personal preferences for outcomes, into treatment decisions when cancer genomics information is also available to estimate individual risk of cancer recurrence.","Although many of the insights from stakeholders shown in Table 1 may be generalizable to other clinical situations where genomic test results provide personalized estimates of cancer recurrence, the relevance of some stakeholder comments may be limited to proposed decision aid programs that employ an analytic approach based upon decision analysis modeling like the one developed by our group.","""So if it's really important to a man to minimize his risk of urinary trouble, for example, he can weight that more heavily."" Their approach can help incorporate other patient-specific factors, such as age and personal preferences for outcomes, into treatment decisions when cancer genomics information is also available to estimate individual risk of cancer recurrence. Findings Published

While the researchers are developing the tool specifically for prostate cancer, they can imagine many other potential applications.","Our stakeholder engagement study provides valuable insights into how to effectively communicate GC results in a patient-centered approach . Although many of the insights from stakeholders shown in Table 1 may be generalizable to other clinical situations where genomic test results provide personalized estimates of cancer recurrence, the relevance of some stakeholder comments may be limited to proposed decision aid programs that employ an analytic approach based upon decision analysis modeling like the one developed by our group. It is important to note that all members of our patient stakeholder group reported at least a college degree, and most members had a graduate degree, so our study may fail to fully reflect the broader population.","[3.0, 2.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.2,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1287/mnsc.2016.2500,Computer_Science_137,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers.","[4.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.75,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_139,"Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings.","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

USC

There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region. Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings.","[5.0, 4.0, 4.0, 5.0, 3.0]",Computer_Science,train,4.2,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1007/s10055-018-0346-3,Computer_Science_14,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ).","The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","Lastly, place cells in the hippocampus activate in specific spatial locations, independent of orientation, providing an internal representation of the environment . This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ). This study found that the users who used a graphics desktop environment as the basis for their method of loci performed better than those using a mental scene of their choice, and those who were not instructed on a memory strategy did not perform as well as those who were instructed to use the memory strategy.","[3.0, 1.0, 4.0, 3.0]",Computer_Science,train,2.75,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1016/j.robot.2015.01.003,Computer_Science_140,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""","Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow.","These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","Having a robot explore its environment for an extended period of time may thus be an inevitable cost to be paid for the autonomous emergence of such perceptual notions. Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow. We thus believe that any perceptive knowledge should be discovered and grounded in sensorimotor experience.","[2.0, 1.0, 2.0]",Computer_Science,train,1.6666666666666667,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1177/1080569913501862,Computer_Science_141,Higher-income professionals had less tolerance for smartphone use in business meetings.,Women showed far less acceptance for the use of mobile phones during informal meetings.,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings. Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings.","[4.0, 1.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.robot.2015.01.003,Computer_Science_142,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.","Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow.","If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","Having a robot explore its environment for an extended period of time may thus be an inevitable cost to be paid for the autonomous emergence of such perceptual notions. Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow. We thus believe that any perceptive knowledge should be discovered and grounded in sensorimotor experience.","[1.0, 1.0, 2.0, 1.0, 3.0]",Computer_Science,train,1.6,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1186/s12911-017-0526-1,Computer_Science_143,"Their approach can help incorporate other patient-specific factors, such as age and personal preferences for outcomes, into treatment decisions when cancer genomics information is also available to estimate individual risk of cancer recurrence.","Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for cancer recurrence risk, as well as competing risks from age and comorbidities, to generate a patient-centered tool to assist decision-making.","""So if it's really important to a man to minimize his risk of urinary trouble, for example, he can weight that more heavily."" Their approach can help incorporate other patient-specific factors, such as age and personal preferences for outcomes, into treatment decisions when cancer genomics information is also available to estimate individual risk of cancer recurrence. Findings Published

While the researchers are developing the tool specifically for prostate cancer, they can imagine many other potential applications.","Results: The majority of stakeholder suggestions focused on aspects of decision aid design and formatting. Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for cancer recurrence risk, as well as competing risks from age and comorbidities, to generate a patient-centered tool to assist decision-making. Stakeholders did not view privacy considerations as a major barrier to the proposed decision aid program.","[3.0, 4.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.4,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1177/1080569913501862,Computer_Science_145,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.",We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings.,"Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West. We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings. We suspect that one explanation is that higher-income at UNIV TORONTO on May 10, 2016 bcq.sagepub.com Downloaded from professionals are often in higher-status positions.","[2.0, 2.0, 4.0]",Computer_Science,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_146,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags. Increased boarding times as a result of baggage fees have financial implications as well.","[2.0, 3.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.4,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_148,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","When the other airlines began charging for the first two checked bags, however, Southwest's decision appears to be in line with their strategy.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","When the other airlines started charging for one checked bag, Southwest Airlines' decision to not charge for bags went against their high operational service level strategy as their relative departure delay performance initially decreased. When the other airlines began charging for the first two checked bags, however, Southwest's decision appears to be in line with their strategy. While bags may not really ""fly free"" in an operational sense at Southwest, not charging passengers for checking bags does seem to help avoid the worst carry-on abuses seen at other airlines that have led to a degradation of on-time departure performance.","[2.0, 4.0, 2.0, 3.0]",Computer_Science,train,2.75,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1126/science.aaf2654,Computer_Science_15,"""This is a challenge that should be on the mind of carmakers and regulators alike,"" the scholars write.",This is a challenge that should be on the mind of carmakers and regulators alike.,"In the survey, respondents said they were only one-third as likely to purchase a vehicle regulated this way, as opposed to an unregulated vehicle, which could presumably be programmed in any fashion. ""This is a challenge that should be on the mind of carmakers and regulators alike,"" the scholars write. Moreover, if autonomous vehicles actually turned out to be safer than regular cars, unease over the dilemmas of regulation ""may paradoxically increase casualties by postponing the adoption of a safer technology.""","Second and worse, our results suggest that such a regulation could significantly delay the adoption of AVswhich means that the lives saved by making AVs utilitarian may be outnumbered by the deaths caused by delaying the adoption of the AVs altogether, with their other safety enhancing technologies. This is a challenge that should be on the mind of carmakers and regulators alike. Moral algorithms for AVs will need to tackle more intricate decisions than that we have considered in our surveys.","[5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1098/rstb.2008.0288,Computer_Science_150,"Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others.",This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se.,"The successful trainees did not perform better on all tests of memory, however. Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others. She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training.","Despite this group showing a wide range of navigational expertise, there was no association between expertise and posterior hippocampal grey matter volume (or, indeed, Review. This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se. Clearly, taxi drivers in London have to learn a vast amount of information.","[3.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,train,3.8,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_151,They found that people remember information better if it is presented to them in a virtual environment.,We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.",We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition. We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"[5.0, 5.0, 4.0, 3.0, 5.0]",Computer_Science,train,4.4,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/s10055-018-0346-3,Computer_Science_152,They found that people remember information better if it is presented to them in a virtual environment.,Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.",The technique of memory palaces provides a natural spatial mnemonic to assist in recall. Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored. Virtual environments that mirror the scene of the crime could provide superior assistance in recall by placing the victim back into such an environment.,"[3.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.25,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_153,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Thus, the implementation of checked bag fees (a marketing decision) provides an ideal setting to study how an industry changed, or coordinated, their operations to respond to this marketing strategy change. Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","[3.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_154,They found that people remember information better if it is presented to them in a virtual environment.,Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[3.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.5,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_155,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.",The same policy may have determined a change in other passengers' behavior in the sense that fewer passengers may have checked a second bag while still flying their preferred airline.,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.",We expect that the price-insensitive passengers or those passengers traveling with only one checked bag were indifferent to this policy change. The same policy may have determined a change in other passengers' behavior in the sense that fewer passengers may have checked a second bag while still flying their preferred airline. Another possible explanation is that price-sensitive customers of those airlines that charged for one checked bag started flying Southwest instead.,"[2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_156,The researchers found that people remember information better if it is presented to them in a virtual environment.,"If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[3.0, 5.0, 4.0, 5.0]",Computer_Science,train,4.25,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1177/1080569913501862,Computer_Science_158,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","Also, higher-income professionals showed lower acceptance for mobile phone use during meetings.","Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","Not surprisingly, younger professionals were more likely to consider various mobile phone behaviors as appropriate during meetings. Also, higher-income professionals showed lower acceptance for mobile phone use during meetings. Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings.","[2.0, 4.0, 2.0]",Computer_Science,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_16,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings.","Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","Women showed far less acceptance for the use of mobile phones during informal meetings. Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings. Based on the findings, we have made several basic conclusions.","[4.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.5,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_160,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Ultimately, operations managers need to be involved in the discussions about marketing initiatives such as this one to evaluate the operational impact of marketing initiatives. We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","[1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_161,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.","These findings indicate that the baggage fees did influence customer behavior, but in the case of charging for both checked bags, not in the direction the airlines had hoped for.","The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","When the airlines began charging for two checked bags, we find no significant change in departure performance of legacy carriers, but a degradation of departure performance of low-cost carriers. These findings indicate that the baggage fees did influence customer behavior, but in the case of charging for both checked bags, not in the direction the airlines had hoped for. The degradation of departure performance appears to be especially bad for the low-cost carriers, as it appears that their more price sensitive passengers may have begun carrying on more baggage to avoid the checked bag fees.","[4.0, 2.0, 1.0, 3.0, 4.0]",Computer_Science,train,2.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_162,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.",Tobit regression model is appropriate here.,"The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","Hence, a Tobit regression model is appropriate here. The estimation model of the impact of the checked bag fees on the spillover-adjusted departure delay is shown in (1).","[3.0, 1.0, 1.0]",Computer_Science,train,1.6666666666666667,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_163,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace. Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall. Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information.","[3.0, 2.0, 3.0, 5.0, 3.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_164,They found that people remember information better if it is presented to them in a virtual environment.,Approximately a third mentioned that they actively used the virtual memory palace setup by associating the information relative to their own body.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","In addition, a majority of the users (70%) reported that HMD afforded them a superior sense of the spatial awareness which they claimed was important to their success. Approximately a third mentioned that they actively used the virtual memory palace setup by associating the information relative to their own body. This ability to associate information with the spatial context around the body only adds to the benefit of increased immersion afforded by the HMD.","[2.0, 4.0, 3.0, 2.0, 5.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1177/1080569913501862,Computer_Science_166,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.",Women showed far less acceptance for the use of mobile phones during informal meetings.,"Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings. Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings.","[3.0, 4.0, 1.0, 1.0, 4.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_168,"With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ).","These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.","In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers. Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ). Clearly, increased numbers of participants are required to confirm these findings.","[2.0, 5.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.4,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_169,The researchers found that people remember information better if it is presented to them in a virtual environment.,"Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall.","Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace. Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall. Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information.","[2.0, 4.0, 2.0, 2.0, 1.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1177/1080569913501862,Computer_Science_17,Higher-income professionals had less tolerance for smartphone use in business meetings.,We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings.,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West. We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings. We suspect that one explanation is that higher-income at UNIV TORONTO on May 10, 2016 bcq.sagepub.com Downloaded from professionals are often in higher-status positions.","[5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_170,The researchers found that people remember information better if it is presented to them in a virtual environment.,"Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","[4.0, 2.0, 1.0, 3.0, 4.0]",Computer_Science,train,2.8,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1007/s10055-018-0346-3,Computer_Science_171,The researchers found that people remember information better if it is presented to them in a virtual environment.,It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace.,"The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall. It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace. Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall.","[4.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1186/s12911-017-0526-1,Computer_Science_172,"The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions.","Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for risk of cancer recurrence and other patient-specific factors such as age, other medical problems and lifestyle.","And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information. The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions. It would be for discussion with their doctor.","It was recommended that the decision aid format be interactive, with patients being able to iteratively adjust model inputs to see the impact on model outcomes. Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for risk of cancer recurrence and other patient-specific factors such as age, other medical problems and lifestyle. Table 2 displays key decision aid elements that were identified based on stakeholder engagement that will be used to design a more effective patient-centered tool.","[5.0, 2.0, 3.0]",Computer_Science,train,3.0,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1007/978-3-642-55220-5_1,Computer_Science_173,The algorithm they devised stands out from the best algorithms known to date for this problem.,The key features of our algorithm are the following.,"Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc. The algorithm they devised stands out from the best algorithms known to date for this problem. Not only is it significantly easier to explain, but its complexity is also considerably improved.","It remains super-polynomial in the size of the input, but offers a major asymptotic improvement compared to L(1/4 + o(1)). The key features of our algorithm are the following. -The algorithmic building blocks are elementary.","[1.0, 2.0, 4.0, 3.0]",Computer_Science,train,2.5,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Computer_Science_175,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","We have established that navigation expertise is associated with structural brain differences and behavioural consequences, both positive and negative. In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed. This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification.","[4.0, 4.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.4,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1098/rstb.2008.0288,Computer_Science_177,"The hippocampus's rear section seems to be important for spatial navigation specifically, but Maguire says the front end's role remains more mysterious.",The hippocampus in humans is therefore necessary for facilitating navigation even when the navigator is an expert of very longstanding.,"She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training. The hippocampus's rear section seems to be important for spatial navigation specifically, but Maguire says the front end's role remains more mysterious. Maguire says she was ""greatly relieved"" by the results of her study, which appears in the December issue of Current Biology.","However, in his navigation, TT was very reliant on main artery or 'A' roads, and became lost when navigation depended instead on non-A roads (figure 4). The hippocampus in humans is therefore necessary for facilitating navigation even when the navigator is an expert of very longstanding. Thus expertise, while taking many years to Review.","[2.0, 1.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1186/s12911-017-0526-1,Computer_Science_179,"The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions.","Conclusions: A range of stakeholders provided valuable insights regarding the design of a personalized decision aid program, based upon Markov modeling with individualized model inputs, to provide a patient-centered framework to support for genomic-based treatment decisions for cancer patients.","And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information. The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions. It would be for discussion with their doctor.","Emphasis was placed on the challenge of explaining the model's composite result of quality-adjusted life years. Conclusions: A range of stakeholders provided valuable insights regarding the design of a personalized decision aid program, based upon Markov modeling with individualized model inputs, to provide a patient-centered framework to support for genomic-based treatment decisions for cancer patients. The guidance provided by our stakeholders may be broadly applicable to the communication of genomic test results to patients in a patient-centered fashion that supports effective shared decision-making that represents a spectrum of personal factors such as age, medical comorbidities, and individual priorities and values.","[4.0, 2.0, 4.0]",Computer_Science,train,3.333333333333333,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1287/mnsc.2016.2500,Computer_Science_180,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers.","[4.0, 3.0, 4.0, 2.0, 2.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_181,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[1.0, 2.0, 4.0, 3.0, 3.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1098/rstb.2008.0288,Computer_Science_183,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","We have established that navigation expertise is associated with structural brain differences and behavioural consequences, both positive and negative. In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed. This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification.","[3.0, 5.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_184,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.",The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","However, participants were susceptible to disorientation if their starting-out views were different between their training and testing. The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms. They found that users in a HMD were better able to keep track of the objects by rotating their heads as compared to using a joystick.","[4.0, 2.0, 2.0, 4.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_185,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports.","Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.","Thus, the implementation of checked bag fees (a marketing decision) provides an ideal setting to study how an industry changed, or coordinated, their operations to respond to this marketing strategy change. Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","[2.0, 5.0, 4.0, 4.0]",Computer_Science,train,3.75,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_186,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed. This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification. This will provide vital information about brain plasticity and navigation expertise, and the factors that might affect or limit the ability to develop such expertise.","[2.0, 3.0, 4.0, 2.0]",Computer_Science,train,2.75,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_187,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.",***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1,"The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","The number of observations used is different from the first dataset sample size due to missing values of Aircraft-Age, Avg-Passengers, Origin-Prcp, Dest-Prcp, Origin-Awnd, and Dest-Awnd variables. ***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1 Our study suggests that in the 35-day period following the date of implementing fees for one checked bag, the airlines that did implement these fees experienced improved relative performance in terms of their departure delays.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_188,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","A notable exception to the charging for checked bags trend was Southwest Airlines, who turned their resistance to this practice into a ""Bags Fly Free"" marketing campaign. At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag.","[4.0, 4.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_189,"With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","Clearly, taxi drivers in London have to learn a vast amount of information.","These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.","This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se. Clearly, taxi drivers in London have to learn a vast amount of information. While our previous work has shown that taxi drivers and their control subjects generally have average IQs Woollett & Maguire in press) , the medical doctors had above-average IQs.","[4.0, 1.0, 5.0, 4.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_19,Higher-income professionals had less tolerance for smartphone use in business meetings.,"Also, higher-income professionals showed lower acceptance for mobile phone use during meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Not surprisingly, younger professionals were more likely to consider various mobile phone behaviors as appropriate during meetings. Also, higher-income professionals showed lower acceptance for mobile phone use during meetings. Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings.","[5.0, 5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_190,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","As seen in Table 7 , the other control variables are also statistically significant.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Similar to Table 6 , the coefficients for the categorical variables for Origin, Route, Carrier, Month, Day-of-Week, Dep-Time-Block, and Arr-Time-Block are not shown in the interest of space, although they are statistically significant. As seen in Table 7 , the other control variables are also statistically significant. Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described.","[1.0, 1.0, 3.0]",Computer_Science,train,1.6666666666666667,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_191,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences. Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al. 2000) .","[5.0, 4.0, 5.0, 4.0, 4.0]",Computer_Science,train,4.4,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_192,"""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.",We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West.,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages. ""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.",A possible explanation for more sensitivity to mobile phone use in the Southwest may be the emphasis on hospitality and manners. We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West. We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings.,"[1.0, 2.0, 2.0, 4.0, 2.0]",Computer_Science,train,2.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_195,The researchers found that people remember information better if it is presented to them in a virtual environment.,The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.,"The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall. It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace.,"[3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.75,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1098/rstb.2008.0288,Computer_Science_196,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.",This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se.,"He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","Despite this group showing a wide range of navigational expertise, there was no association between expertise and posterior hippocampal grey matter volume (or, indeed, Review. This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se. Clearly, taxi drivers in London have to learn a vast amount of information.","[4.0, 1.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.6,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_197,"More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors.","Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate. Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women.","One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions. As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors. These survey results seem to indicate that women professionals hold different norms of civility as far as mobile phone use during informal meetings.","[3.0, 2.0, 5.0, 3.0, 4.0]",Computer_Science,train,3.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_198,"Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others.","The improvement of performance on tests such as the Rey Figure by the retired taxi drivers is also interesting in that it may indicate that the 'elderly' hippocampus can support memory improvement, in contrast with the more traditional view of age-related memory decline.","The successful trainees did not perform better on all tests of memory, however. Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others. She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training.","during acquisition and use of expertise, and then again when use of the skill ceases, serves to highlight that expertise and its behavioural consequences may be plastic and, in the case of the hippocampus at least, so are the related structural brain changes. The improvement of performance on tests such as the Rey Figure by the retired taxi drivers is also interesting in that it may indicate that the 'elderly' hippocampus can support memory improvement, in contrast with the more traditional view of age-related memory decline. First, this issue has universal relevance by informing what each of us can hope to achieve, and providing much-needed insights into the basis of individual differences, as well as having relevance in the realm of education.","[2.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_200,"In a sense, the traditional second law only holds on average.","This paradigm is equivalent to ones in which we allow interaction Hamiltonians rather than unitaries, or where we allow for a Hamiltonian which changes with time, provided that all ancillas are carefully accounted for [ .","""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","Operations which pump energy into or from the system can be incorporated into the paradigm by including the source of energy as an ancillary system. This paradigm is equivalent to ones in which we allow interaction Hamiltonians rather than unitaries, or where we allow for a Hamiltonian which changes with time, provided that all ancillas are carefully accounted for [ . Considering such resources are crucial, since the experimenter who is trying to extract work or otherwise manipulate a system, should be allowed as much ingenuity as possible.","[1.0, 1.0, 3.0, 1.0, 3.0]",Computer_Science,train,1.8,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2552/aabc9b,Computer_Science_201,"""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr.",Another possibility is that bilateral adaptive stimulation may be necessary for clinical benefit and that this is why we did not see a clinical improvement (since we tested only unilateral adaptive DBS).,"An adaptive system like the one being tested here could offer an effective alternative and may also limit adverse effects of traditional deep brain stimulation, but considerable testing remains to be done. ""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr. ""We are now planning larger, longer-term trials to determine how effective this system is in managing the symptoms of patients with Parkinson's disease.""","Indeed, it is possible there could have been a floor effect for dyskinesia in this study since dyskinesia was mild for all conditions (see Table 3 ). Another possibility is that bilateral adaptive stimulation may be necessary for clinical benefit and that this is why we did not see a clinical improvement (since we tested only unilateral adaptive DBS). Another consideration is that our results apply specifically to STN DBS, which is currently the most commonly used target for DBS in PD.","[4.0, 4.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1126/science.aaf2654,Computer_Science_202,"Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest.""","Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.","""If everybody does that, then we would end up in a tragedy ... whereby the cars will not minimize casualties,"" Rahwan adds. Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","For example, our scenarios did not feature any uncertainty about decision outcomes, but a collective discussion about moral algorithms will have to tackle the concepts of expected risk, expected value, and blame assignment. Such liability considerations will need to accompany existing discussions of regulation [21] , and we hope that psychological studies inspired by our own will be able to inform this discussion. Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.","[3.0, 1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.6,news,http://www.science20.com/news_articles/driverless_cars_who_gets_protected-175287
10.1177/1080569913501862,Computer_Science_203,"Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings.","Overwhelmingly, taking or making calls during meetings were the most commonly cited examples, with more than one half of employees who commented about meetings stating they had recently observed this behavior and considered it disrespectful.","Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude. Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.","Altogether, 101 of the 204 employees (49.5%) commented on mobile phone behaviors in meetings. Overwhelmingly, taking or making calls during meetings were the most commonly cited examples, with more than one half of employees who commented about meetings stating they had recently observed this behavior and considered it disrespectful. Writing and reading text messages or emails followed, with roughly one third of the employees citing these actions as recent examples of disrespectful phone use.","[4.0, 2.0, 4.0, 4.0, 4.0]",Computer_Science,train,3.6,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_204,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",They serve to alter consumer behavior in a manner that is beneficial to both the firm and customers.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","While investigating whether the social planner would let bags fly free, argue that ""baggage fees are not just about revenue. They serve to alter consumer behavior in a manner that is beneficial to both the firm and customers. The firm enjoys lower costs and passes some of these savings on to customers"".","[1.0, 3.0, 1.0]",Computer_Science,train,1.6666666666666667,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_205,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ).","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","In comparison with the posterior hippocampus that had greater grey matter volume compared with control participants, the anterior hippocampus had reduced grey matter volume in taxi drivers (Maguire et al. Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ). We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume.","[2.0, 2.0, 3.0, 1.0, 3.0]",Computer_Science,train,2.2,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_206,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",Standard errors are shown in parantheses.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","average delay in the After period minus average delay in the Before period. Standard errors are shown in parantheses. The number of observations used is different from the second dataset sample size due to missing values of Actual-TurnAround-Time, Aircraft-Age and Avg-Passengers variables.","[1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.5,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_207,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.",The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms.,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.","However, participants were susceptible to disorientation if their starting-out views were different between their training and testing. The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms. They found that users in a HMD were better able to keep track of the objects by rotating their heads as compared to using a joystick.","[2.0, 2.0, 1.0, 3.0, 3.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1007/s10055-018-0346-3,Computer_Science_208,They found that people remember information better if it is presented to them in a virtual environment.,The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.",This makes it possible to compare recall for the same user across the two display modalities. The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop. They found that active participants had a superior environment layout recall compared to those who were passive.,"[4.0, 3.0, 5.0, 5.0, 3.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1177/1080569913501862,Computer_Science_209,"A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region.","Since mobile phone use for professional purposes is likely to increase, we think that examining the related social norms is a particularly useful line of inquiry for business communication.","But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity. A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","Second, we did not capture how the status of meeting participants affects norms of civility for mobile phone use. Since mobile phone use for professional purposes is likely to increase, we think that examining the related social norms is a particularly useful line of inquiry for business communication. We recommend additional research that addresses the following issues: (a) the impact of mobile phone preferences and attitudes on actual behavior, (b) the impact of status differentials on mobile phone norms and behaviors, (c) distinctions between social norms and behaviors for in-person and virtual meetings, and (d) social norms and behaviors for emerging forms of mobile devices such as tablets.","[3.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Computer_Science_21,"For instance, 76 percent of respondents believe it is more moral for an autonomous vehicle, should such a circumstance arise, to sacrifice one passenger rather than 10 pedestrians.","In Study 1 (n = 182), 76% of participants thought that it would be more moral for AVs to sacrifice one passenger, rather than kill ten pedestrians (with a 95% confidence interval of 69-82).","The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved. For instance, 76 percent of respondents believe it is more moral for an autonomous vehicle, should such a circumstance arise, to sacrifice one passenger rather than 10 pedestrians. But the surveys also revealed a lack of enthusiasm for buying or using a driverless car programmed to avoid pedestrians at the expense of its own passengers.","Overall, participants strongly agreed that it would be more moral for AVs to sacrifice their own passengers, when this sacrifice would save a greater number of lives overall. In Study 1 (n = 182), 76% of participants thought that it would be more moral for AVs to sacrifice one passenger, rather than kill ten pedestrians (with a 95% confidence interval of 69-82). They overwhelmingly expressed a moral preference for utilitarian AVs programmed to minimize the number of casualties (median = 85, Fig.","[5.0, 5.0, 5.0, 5.0, 4.0]",Computer_Science,train,4.8,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1007/s10055-018-0346-3,Computer_Science_212,"In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",The study found that immediately after the exposure the participants had the most accurate recall in the real-world scene and were slightly less accurate and confident in the HMD and least accurate and confident on the desktop.,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","They found that the users wearing the HMD had faster navigation times and less waste-full movement and were more accurately able to estimate distances, compared to those using a desktop. The study found that immediately after the exposure the participants had the most accurate recall in the real-world scene and were slightly less accurate and confident in the HMD and least accurate and confident on the desktop. After one week, the overall scores and confidence levels dropped consistently across the board, with the viewing condition having no effect on the relative reduction in performance.","[3.0, 2.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1126/science.aaf2654,Computer_Science_213,"Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest.""","To align moral algorithms with human values, we must start a collective discussion about the ethics of AVs, that is, the moral algorithms that we are willing to accept as citizens and to be subjected to as car owners.","""If everybody does that, then we would end up in a tragedy ... whereby the cars will not minimize casualties,"" Rahwan adds. Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","Even though such situations may be exceedingly rare, their emotional saliency is likely to give them broad public exposure and a disproportionate weight in individual and public decisions about AVs. To align moral algorithms with human values, we must start a collective discussion about the ethics of AVs, that is, the moral algorithms that we are willing to accept as citizens and to be subjected to as car owners. A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far.","[3.0, 3.0, 4.0, 1.0, 2.0]",Computer_Science,train,2.6,news,http://www.science20.com/news_articles/driverless_cars_who_gets_protected-175287
10.1186/s12911-017-0526-1,Computer_Science_215,And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information.,"Conclusions: A range of stakeholders provided valuable insights regarding the design of a personalized decision aid program, based upon Markov modeling with individualized model inputs, to provide a patient-centered framework to support for genomic-based treatment decisions for cancer patients.","/ no comments

Medicine, Health Care UVA Aims to Help Patients... And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information. The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions.","Emphasis was placed on the challenge of explaining the model's composite result of quality-adjusted life years. Conclusions: A range of stakeholders provided valuable insights regarding the design of a personalized decision aid program, based upon Markov modeling with individualized model inputs, to provide a patient-centered framework to support for genomic-based treatment decisions for cancer patients. The guidance provided by our stakeholders may be broadly applicable to the communication of genomic test results to patients in a patient-centered fashion that supports effective shared decision-making that represents a spectrum of personal factors such as age, medical comorbidities, and individual priorities and values.","[3.0, 5.0, 2.0, 3.0]",Computer_Science,train,3.25,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1287/mnsc.2016.2500,Computer_Science_217,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.",Worse relative performance as measured by departure delays is achieved when charging for one checked bag versus not charging for a checked bag.,"The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Better relative performance as measured by departure delays is achieved when charging for one checked bag versus not charging for a checked bag. Worse relative performance as measured by departure delays is achieved when charging for one checked bag versus not charging for a checked bag. Further, when the airlines which were charging their passengers for one checked bag instituted a policy change by charging the first two checked bags (see Table 2 for exact dates), both x 2 and x 1 passengers were affected, depending on their price sensitivity.","[3.0, 1.0, 4.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_22,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","The coefficient for the Bag-Fee indicator variable which indicates one checked bag fee as being implemented, is negative and statistically significant (-1.8701; p<0.0001). This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees. In other words, the airlines that implemented the fee for one checked bag saw their departure performance improve, whereas Southwest Airlines experienced a negative impact on its departure performance.","[3.0, 4.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.4,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_220,Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.,One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions.,"Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","This seems to indicate major generational differences. One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions. As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors.","[4.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.75,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_222,"These navigational demands stimulate brain development, concludes a study five years in the making.","However, fMRI scanning revealed that they activated brain areas associated with navigation, including the hippocampus, more than control participants.","A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","Exceptional memory in these individuals was not found to be associated with higher IQ or any structural brain differences relative to control participants . However, fMRI scanning revealed that they activated brain areas associated with navigation, including the hippocampus, more than control participants. With extensive practice, this method is effective at enabling one to remember the order of stimuli by imagining familiar routes and placing the to-be-remembered items along the routes thus promoting deeper encoding of the stimuli with rich associations.","[4.0, 4.0, 3.0, 1.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_224,Higher-income professionals had less tolerance for smartphone use in business meetings.,"Second, we did not capture how the status of meeting participants affects norms of civility for mobile phone use.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","We note several limitations. Second, we did not capture how the status of meeting participants affects norms of civility for mobile phone use. Since mobile phone use for professional purposes is likely to increase, we think that examining the related social norms is a particularly useful line of inquiry for business communication.","[2.0, 4.0, 1.0, 2.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Computer_Science_225,"Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest.""",Defining the algorithms that will help AVs make these moral decisions is a formidable challenge.,"""If everybody does that, then we would end up in a tragedy ... whereby the cars will not minimize casualties,"" Rahwan adds. Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","Defining the algorithms that will help AVs make these moral decisions is a formidable challenge. We found that participants to six MTurk studies approved of utilitarian AVs (that sacrifice their passengers for the greater good), and would like others to buy them; but they would themselves prefer to ride in AVs that protect their passengers at all costs. They would disapprove of enforcing utilitarian AVs, and would be less willing to buy such a regulated AV.","[5.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.5,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1287/mnsc.2016.2500,Computer_Science_227,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","Consequently, the implementation of checked baggage fees resulted in reduced likelihood of on-time departures as long as the carry-on baggage limits were loosely enforced.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Indeed, checked baggage fees led to more and heavier bags brought as carry-on into the cabin . Consequently, the implementation of checked baggage fees resulted in reduced likelihood of on-time departures as long as the carry-on baggage limits were loosely enforced. The passengers can also check more than two bags, however these extra-bags have always incurred additional fees, thus our discussion reduces to their behavior regarding the first two checked bags.","[5.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1411728112,Computer_Science_228,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.",This means that the following transition is possible,"It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","W can be either negative or positive, depending on whether work is used from or stored in the battery system. This means that the following transition is possible For this transformation to be possible, it is required in Theorem 17 that the following conditions hold for all α ≥ 0,","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.compag.2016.07.028,Computer_Science_229,"The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","Here we show that hyperspectral imaging can predict LWC accurately (in case of B73, a prediction accuracy of ±2.3% is achieved as indicated by RMSE CV ).","Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said. But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant.","Total NIR reflectance appears to be influenced by leaf thickness in addition to water content, introducing confound- ing variation ( . Here we show that hyperspectral imaging can predict LWC accurately (in case of B73, a prediction accuracy of ±2.3% is achieved as indicated by RMSE CV ). The advantages of hyperspectral imaging come from several aspects.","[1.0, 2.0, 1.0, 2.0, 3.0]",Computer_Science,train,1.8,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1287/mnsc.2016.2500,Computer_Science_23,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",Our research also sheds some light on the decisions made by a very operationally focused airline.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes. Our research also sheds some light on the decisions made by a very operationally focused airline. When the other airlines started charging for one checked bag, Southwest Airlines' decision to not charge for bags went against their high operational service level strategy as their relative departure delay performance initially decreased.","[4.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.5,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.robot.2015.01.003,Computer_Science_230,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""","Even if sensations s depend on the environment, the sets M s are thus environmentindependent.","These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","Those particular cases aside, every set M s corresponds to a certain input s but also to a certain position of the agent in space. Even if sensations s depend on the environment, the sets M s are thus environmentindependent. All the possible sets M i have a specific structure that can be captured to build an internal representation of the external agent's configuration.","[2.0, 3.0, 3.0, 1.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1098/rstb.2008.0288,Computer_Science_231,"In other words, taxi drivers had plumper memory centers than their peers.","Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ).","Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks. In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers. Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ). Clearly, increased numbers of participants are required to confirm these findings.","[5.0, 4.0, 3.0, 5.0, 4.0]",Computer_Science,train,4.2,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_232,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ).","The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","Lastly, place cells in the hippocampus activate in specific spatial locations, independent of orientation, providing an internal representation of the environment . This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ). This study found that the users who used a graphics desktop environment as the basis for their method of loci performed better than those using a mental scene of their choice, and those who were not instructed on a memory strategy did not perform as well as those who were instructed to use the memory strategy.","[1.0, 3.0, 4.0, 4.0, 4.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1287/mnsc.2016.2500,Computer_Science_233,"The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.",Another possible explanation is that price-sensitive customers of those airlines that charged for one checked bag started flying Southwest instead.,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","The same policy may have determined a change in other passengers' behavior in the sense that fewer passengers may have checked a second bag while still flying their preferred airline. Another possible explanation is that price-sensitive customers of those airlines that charged for one checked bag started flying Southwest instead. While it is obvious that additional passengers generate additional revenues for an airline, it is less obvious that more passengers represent an increased likelihood of departure delays.","[2.0, 2.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1411728112,Computer_Science_235,"In a sense, the traditional second law only holds on average.",This means that the following transition is possible,"""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","W can be either negative or positive, depending on whether work is used from or stored in the battery system. This means that the following transition is possible For this transformation to be possible, it is required in Theorem 17 that the following conditions hold for all α ≥ 0,","[4.0, 1.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.2,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1287/mnsc.2016.2500,Computer_Science_236,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",Better relative performance as measured by departure delays is achieved when charging for the first two checked bags versus charging only for one checked bag.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Similar to the one checked bag fee policy, the theory does not offer a clear direction of the impact of the first two checked bags fees policy on departure delays, and hence we let the data dictate the correct hypothesis: Better relative performance as measured by departure delays is achieved when charging for the first two checked bags versus charging only for one checked bag. Worse relative performance as measured by departure delays is achieved when charging for the first two checked bags versus charging only for one checked bag.","[3.0, 1.0, 3.0, 3.0, 3.0]",Computer_Science,train,2.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_238,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings.","Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.","In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region. Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings.","[4.0, 3.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_239,"Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","Showing these figures and tables can also foster productive conversations about how generation, gender, and status affect perceptions of appropriate mobile phone use in formal and informal settings.","A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use. Among their findings:

Three out of four people -- 76 percent -- said checking texts or emails was unacceptable behavior in business meetings.","It also equips instructors and trainers with a current set of statistics about norms of civility associated with various mobile phone behaviors in formal and informal meetings. Business communication instructors and trainers can use the tables and figures in this article to help business students and professionals gain awareness of some of the dramatic generational and gender differences. Showing these figures and tables can also foster productive conversations about how generation, gender, and status affect perceptions of appropriate mobile phone use in formal and informal settings.","[3.0, 4.0, 3.0, 2.0, 3.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_24,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.",This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[5.0, 2.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.4,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_241,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.","The coefficient for the Bag-Fee indicator variable which indicates one checked bag fee as being implemented, is negative and statistically significant (-1.8701; p<0.0001).","The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","The results of the estimation of our Tobit1 model are shown in Table 6 14 . The coefficient for the Bag-Fee indicator variable which indicates one checked bag fee as being implemented, is negative and statistically significant (-1.8701; p<0.0001). This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees.","[3.0, 4.0, 3.0]",Computer_Science,train,3.333333333333333,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_243,The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.,"Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports.","Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year. ""It's not free in an operational sense,"" Arikan says.","Thus, the implementation of checked bag fees (a marketing decision) provides an ideal setting to study how an industry changed, or coordinated, their operations to respond to this marketing strategy change. Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","[3.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_244,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.",The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms.,"The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","However, participants were susceptible to disorientation if their starting-out views were different between their training and testing. The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms. They found that users in a HMD were better able to keep track of the objects by rotating their heads as compared to using a joystick.","[3.0, 3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.8,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_245,"In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces.,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.",We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition. We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"[2.0, 4.0, 3.0, 4.0, 2.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.robot.2015.01.003,Computer_Science_246,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,"In some sense, the sensory manifold S describes the agent's internal experience of its translation in space, and is the only information it can gather about space.","Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","This result was expected, as the dimensionality of the manifold S is determined by the number of degrees of freedom during exploration . In some sense, the sensory manifold S describes the agent's internal experience of its translation in space, and is the only information it can gather about space. However, S depends dramatically on the environment: the same exploratory movements performed in a different environment E will yield another sensory manifold S , which is totally different from S (see Fig.","[2.0, 3.0, 2.0, 1.0, 3.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1411728112,Computer_Science_248,"""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state.","In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is. In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state. These second laws are not only relevant for small systems, but also apply to individual macroscopic systems interacting via long-range interactions, which only satisfy the ordinary second law on average.","[2.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.75,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1177/1080569913501862,Computer_Science_249,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.",One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions.,"Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.","This seems to indicate major generational differences. One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions. As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors.","[2.0, 1.0, 4.0, 2.0, 2.0]",Computer_Science,train,2.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_25,"With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus.","These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.","These effects can be positive and negative, with increased expertise and grey matter volume in some brain regions occurring in tandem with decreased performance on other tasks and decreased grey matter volume in neighbouring brain areas. Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition.","[2.0, 2.0, 4.0, 2.0]",Computer_Science,train,2.5,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1088/1741-2552/aabc9b,Computer_Science_250,Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects.,"Moreover, during DBS at typical frequencies (i.e.130-10 Hz), if dyskinesia is present, the narrowband gamma oscillation occurs reliably at half the stimulation frequency , possibly because of neuronal entrainment (Figure 1A and 1C) .","The device differs from traditional ones in that it can both monitor and modulate brain activity. Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects. Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers.","It is not strongly modulated by voluntary movement and is distinct from the canonical broadband gamma changes that occur in motor cortex during voluntary movement. Moreover, during DBS at typical frequencies (i.e.130-10 Hz), if dyskinesia is present, the narrowband gamma oscillation occurs reliably at half the stimulation frequency , possibly because of neuronal entrainment (Figure 1A and 1C) . Since this signature of dyskinesia is not disrupted by voluntary movement and occurs in a predictable frequency range, it is a promising control signal for adaptive DBS.","[3.0, 3.0, 4.0, 1.0, 4.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1073/pnas.1411728112,Computer_Science_252,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","Conversely, it is easy to see that the only process that conserves energy for an aribtrary state must commute with the Hamiltonian.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","What one means by close will determine which family of second laws apply, and in the subsequent statement we invoke the most stringent conditions, namely closeness in terms of work distance, Note that the demand that the unitary commutes with the total Hamiltonian implies that energy is conserved. Conversely, it is easy to see that the only process that conserves energy for an aribtrary state must commute with the Hamiltonian. We emphasize that the equivalence of this paradigm to others has already been addressed in .","[1.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.2,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1177/1080569913501862,Computer_Science_253,"Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.",Table 3 shows the perceived appropriateness of these various mobile phone behaviors during formal meetings at the workplace.,"A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use. Among their findings:

Three out of four people -- 76 percent -- said checking texts or emails was unacceptable behavior in business meetings.","The intensity of these comments was stronger when talking about what managers do. Table 3 shows the perceived appropriateness of these various mobile phone behaviors during formal meetings at the workplace. More than three quarters of respondents considered making or answering a call (87.1%), writing and sending texts or emails (84.0%), checking texts or emails (76.0%), and browsing the Internet (75.7%) as rarely or never acceptable in formal meetings.","[4.0, 3.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1088/1741-2552/aabc9b,Computer_Science_254,"""We found in this proof-of-principal demonstration that we could implement this adaptive stimulation using a brain signal to adjust therapeutic delivery,"" says Swann.",Significance-This is the first demonstration of adaptive DBS in Parkinson's disease using a fully implanted device and neural sensing.,"The approach also delivered energy savings for the battery-powered device. ""We found in this proof-of-principal demonstration that we could implement this adaptive stimulation using a brain signal to adjust therapeutic delivery,"" says Swann. ""We found we could do it without any negative effects in the patients.","In short term in-clinic testing, energy savings were substantial (38-45%), and therapeutic efficacy was maintained. Significance-This is the first demonstration of adaptive DBS in Parkinson's disease using a fully implanted device and neural sensing. Our approach is distinct from other strategies utilizing basal ganglia signals for feedback control.","[3.0, 3.0, 2.0, 3.0, 1.0]",Computer_Science,train,2.4,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1016/j.robot.2015.01.003,Computer_Science_255,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""","This approach, when applied to visual information, can lead to the discovery of stable features, such as edges, similar to those present in the human visual cortex .","These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","Perceptual structures can emerge as stable patterns in the agent's sensorimotor flow. This approach, when applied to visual information, can lead to the discovery of stable features, such as edges, similar to those present in the human visual cortex . A similar approach, formalized in the language of information theory , can make it possible to describe the topological structure of the agent's surface and certain properties of its interaction with the environment .","[2.0, 1.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1098/rstb.2008.0288,Computer_Science_256,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","The same is true of non-taxi drivers when they imagined navigating between the houses of friends in London , and when they navigated around various VR environments .","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","Conveniently, one can simply navigate freely (with the usual game scenarios suspended) around the city using the game console, with a normal ground-level first-person perspective, in a car of one's choice. The same is true of non-taxi drivers when they imagined navigating between the houses of friends in London , and when they navigated around various VR environments . 3.","[1.0, 3.0, 3.0, 3.0]",Computer_Science,train,2.5,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_257,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","The same holds true for other versions of the second law, such as the Kelvin-Planck statement, where one also talks about cyclic processes, in which all other objects beside the system of interest are returned back to their original state.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","Interpreted strictly, the Clausius statement of the second law, applies to situations which never occur in nature. The same holds true for other versions of the second law, such as the Kelvin-Planck statement, where one also talks about cyclic processes, in which all other objects beside the system of interest are returned back to their original state. While macroscopically, only a single second law restricts transitions, we find that there are an entire family of more fundamental restrictions at the quantum level.","[3.0, 2.0, 3.0]",Computer_Science,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1177/1080569913501862,Computer_Science_259,"""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings.","With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages. ""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region. Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings.","[1.0, 3.0, 4.0, 5.0, 2.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_260,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.",Tobit regression model is appropriate here.,"The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","Hence, a Tobit regression model is appropriate here. The estimation model of the impact of the checked bag fees on the spillover-adjusted departure delay is shown in (1).","[1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2552/aabc9b,Computer_Science_261,Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects.,We have demonstrated the feasibility of adaptive DBS using a cortical detector sensitive to dyskinesia in two patients.,"The device differs from traditional ones in that it can both monitor and modulate brain activity. Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects. Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers.","Adaptive control algorithms utilizing STN beta band oscillations also showed rapid transitions in the classifier with frequent fluctuations in DBS amplitude 1 , but these fluctuations nevertheless served to ""shape"" the neural signal in a therapeutically useful way, by shortening the duration of ""bursts"" of beta activity . We have demonstrated the feasibility of adaptive DBS using a cortical detector sensitive to dyskinesia in two patients. In both patients there were energy savings without worsening of clinical symptoms.","[1.0, 3.0, 4.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1098/rstb.2008.0288,Computer_Science_262,"These navigational demands stimulate brain development, concludes a study five years in the making.",This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se.,"A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","Despite this group showing a wide range of navigational expertise, there was no association between expertise and posterior hippocampal grey matter volume (or, indeed, Review. This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se. Clearly, taxi drivers in London have to learn a vast amount of information.","[2.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.25,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_264,"""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","The above criteria should not be applied to the system of interest alone, but the system plus any additional resources which are used to enable the transition.","In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","One can make a previously impossible transition possible by adding work in the form of the pure state ψW which will scale each point by an amount e −βW horizontally [5] . The above criteria should not be applied to the system of interest alone, but the system plus any additional resources which are used to enable the transition. In the example above, figure (a) we cannot transform ρ into ρ without performing work (or visa-versa).","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1177/1080569913501862,Computer_Science_265,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.",It also equips instructors and trainers with a current set of statistics about norms of civility associated with various mobile phone behaviors in formal and informal meetings.,"Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.",This study provides strong support for the need to use mobile phones civilly. It also equips instructors and trainers with a current set of statistics about norms of civility associated with various mobile phone behaviors in formal and informal meetings. Business communication instructors and trainers can use the tables and figures in this article to help business students and professionals gain awareness of some of the dramatic generational and gender differences.,"[5.0, 4.0, 3.0, 1.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1411728112,Computer_Science_266,"In a sense, the traditional second law only holds on average.","These second laws are not only relevant for small systems, but also apply to individual macroscopic systems interacting via long-range interactions, which only satisfy the ordinary second law on average.","""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state. These second laws are not only relevant for small systems, but also apply to individual macroscopic systems interacting via long-range interactions, which only satisfy the ordinary second law on average. By making precise the definition of thermal operations, the laws of thermodynamics take on a simple form with the first law defining the class of thermal operations, the zeroeth law, as derived here, emerging as a unique condition ensuring the theory is nontrivial, and the remaining laws being a monotonicity property of our generalised free energies.","[3.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.neuroimage.2014.02.004,Computer_Science_268,"These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions.","Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie .","""The analysis revealed important similarities between brain signals of different people during movie viewing. These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions. The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research.","These findings demonstrate the capability of the proposed methodology to uncover cortical MEG signatures from single-trial signals that are consistent across spectators of a movie. Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie . Emotional video clips, compared with non-emotional ones, increase intersubject synchronization of voxel-wise fMRI time courses in many brain areas, for example in the dorsal attention network .","[3.0, 3.0, 2.0]",Computer_Science,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1287/mnsc.2016.2500,Computer_Science_271,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","Thus, our findings also support the notion that Southwest's marketing strategy of being the only major U.S. airline not charging for the first two checked bags is in line with their historical operations oriented strategy. use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway. Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays.","[3.0, 1.0, 4.0, 1.0]",Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/978-3-642-55220-5_1,Computer_Science_272,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,"Assuming the same heuristics as in Proposition 2, any discrete logarithm in K can be computed in a time bounded by max(q, k) O(log k) .","Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","Since any polynomial in q and k is absorbed in the O() notation in the exponent, we obtain the following result. Assuming the same heuristics as in Proposition 2, any discrete logarithm in K can be computed in a time bounded by max(q, k) O(log k) . In the first one, the finite field admits a sparse medium subfield representation, where q and k are almost equal.","[1.0, 1.0, 2.0, 2.0, 2.0]",Computer_Science,train,1.6,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Computer_Science_274,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.",We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume.,"He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ). We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume. This accords with the findings across species that there may be functional differentiation along the anterior-posterior axis of the hippocampus (e.g.","[2.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.compag.2016.07.028,Computer_Science_275,"The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers.","Second, hyperspectral images are capably of capturing the full spectral signature of plants, allowing more advanced analytical tools such as PLSR for modeling of leaf biochemical properties.","The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers. The crop's unwieldy size and complex anatomy have left it mostly ignored by previous automated phenotyping work, the researchers said. We were fairly successful in doing that.""","First, using different image bands in the hyperspectral cube, plants can be more accurately segmented from the background and leaves can be accurately distinguished from stems (which is quite challenging with a RGB or NIR image). Second, hyperspectral images are capably of capturing the full spectral signature of plants, allowing more advanced analytical tools such as PLSR for modeling of leaf biochemical properties. Based on these previous knowledges, hyperspectral imaging is suggested as a powerful tool in plant phenotyping to complement RGB analysis (to obtain plant chemical traits in addition to morphological traits).","[5.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_276,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.",The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","However, participants were susceptible to disorientation if their starting-out views were different between their training and testing. The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms. They found that users in a HMD were better able to keep track of the objects by rotating their heads as compared to using a joystick.","[3.0, 3.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/s10055-018-0346-3,Computer_Science_278,"""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says.",Virtual environments that mirror the scene of the crime could provide superior assistance in recall by placing the victim back into such an environment.,"The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education. ""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says. ""We believe the future of education and innovation will benefit greatly from the use of these new visual technologies.""",Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored. Virtual environments that mirror the scene of the crime could provide superior assistance in recall by placing the victim back into such an environment. -Hypothesis 1: The participant memory recall accuracy will be higher in the HMD condition as compared to the desktop condition due to the increased immersion.,"[3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.75,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1287/mnsc.2016.2500,Computer_Science_279,The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.,"Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes.","Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year. ""It's not free in an operational sense,"" Arikan says.","While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance. Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes. Our research also sheds some light on the decisions made by a very operationally focused airline.","[3.0, 2.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_281,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","Beyond representational biases, successful qualification might also depend on genetic factors, with perhaps the propensity for hippocampal plasticity more likely in individuals with a certain genetic profile Hariri et al.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","It may be that some individuals have an innate bias for using one type of representation, with successful taxi drivers perhaps more likely to use map-like strategies. Beyond representational biases, successful qualification might also depend on genetic factors, with perhaps the propensity for hippocampal plasticity more likely in individuals with a certain genetic profile Hariri et al. Preliminary data show that the full-timers are indeed significantly better at navigation in London than the retired taxi drivers (figure 6a).","[4.0, 2.0, 5.0, 3.0, 3.0]",Computer_Science,train,3.4,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.robot.2015.01.003,Computer_Science_282,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.","However, S depends dramatically on the environment: the same exploratory movements performed in a different environment E will yield another sensory manifold S , which is totally different from S (see Fig.","If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","In some sense, the sensory manifold S describes the agent's internal experience of its translation in space, and is the only information it can gather about space. However, S depends dramatically on the environment: the same exploratory movements performed in a different environment E will yield another sensory manifold S , which is totally different from S (see Fig. Consequently, it is difficult for the agent to extract knowledge about space -which should be independent of the state of the environment -from exteroceptive experience.","[4.0, 2.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1177/1080569913501862,Computer_Science_283,"When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age.",Women showed far less acceptance for the use of mobile phones during informal meetings.,"Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



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Those differences are still there, if less pronounced, for more formal meetings:

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Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Just as with formal meetings, younger professionals were more likely to accept mobile phone use during informal meetings. Women showed far less acceptance for the use of mobile phones during informal meetings. Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings.","[4.0, 5.0, 5.0, 5.0, 4.0]",Computer_Science,train,4.6,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1177/1080569913501862,Computer_Science_285,"The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.",We found that the literature falls short in several ways in identifying how mobile phone behaviors at meetings are perceived as appropriate or not.,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages. ""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","The authors concluded that although mobile phone use in meetings is becoming more acceptable, it is still generally considered rude, inappropriate, or distracting during most meetings. We found that the literature falls short in several ways in identifying how mobile phone behaviors at meetings are perceived as appropriate or not. We think that additional mobile phone behaviors should be examined.","[2.0, 1.0, 1.0, 3.0, 3.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Computer_Science_286,"The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","When asked whether they would agree to see such moral sacrifices legally enforced, their agreement was higher for algorithms than for human drivers (p < 0.002), but the average agreement still remained below the midpoint of the 0-100 scale in each scenario.","Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved. For instance, 76 percent of respondents believe it is more moral for an autonomous vehicle, should such a circumstance arise, to sacrifice one passenger rather than 10 pedestrians.","As usual, the perceived morality of the sacrifice was high, and about the same whether the sacrifice was performed by a human or by an algorithm (median = 70). When asked whether they would agree to see such moral sacrifices legally enforced, their agreement was higher for algorithms than for human drivers (p < 0.002), but the average agreement still remained below the midpoint of the 0-100 scale in each scenario. Agreement was highest in the scenario where algorithms saved 10 lives, with a 95% confidence interval of 33-46.","[2.0, 1.0, 1.0, 2.0, 3.0]",Computer_Science,train,1.8,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1007/978-3-642-55220-5_1,Computer_Science_287,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,"As a consequence, our algorithm is asymptotically faster than the Function Field Sieve algorithm in almost all the range previously covered by this algorithm.","Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","More precisely, in finite fields of the form F q k , where q grows as L q k (α), the complexity becomes L q k (α + o(1)). As a consequence, our algorithm is asymptotically faster than the Function Field Sieve algorithm in almost all the range previously covered by this algorithm. Whenever α < 1/3, our new algorithm offers the smallest complexity.","[1.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10055-018-0346-3,Computer_Science_288,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.",Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups. Much as textbooks and videos are used today for knowledge dissemination, it could be possible for virtual memory palaces to be used one day for effective transfer of mnemonic devices among humans in virtual environments.","[2.0, 1.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1098/rstb.2008.0288,Computer_Science_289,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.",Negative effects of navigation expertise were not only found behaviourally but also structurally in the brain.,"In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","This pattern of anterograde memory performance was in the context of learning and recognition memory for single items being comparable with control participants, as were retrograde memory for autobiographical and semantic information, executive and perceptual functions, working memory and levels of stress and anxiety. Negative effects of navigation expertise were not only found behaviourally but also structurally in the brain. In comparison with the posterior hippocampus that had greater grey matter volume compared with control participants, the anterior hippocampus had reduced grey matter volume in taxi drivers (Maguire et al.","[4.0, 3.0, 4.0]",Computer_Science,train,3.6666666666666665,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1419704112,Computer_Science_290,"Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar.","Restricting our analysis to basic vocabulary items helped to limit the problem of semantic shift, where cognate terms take on new meanings in some descendant languages.","So it seems possible that with the globalisation made possible through the Internet, the English language should be changing at a faster rate than ever before. Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""","By using cognate terms for basic vocabulary items, we could compare terms that were homologous across languages and had retained a common meaning. Restricting our analysis to basic vocabulary items helped to limit the problem of semantic shift, where cognate terms take on new meanings in some descendant languages. It also helped ensure that we had comparable data for each of our language pairs: each of the languages had nearly all of the basic vocabulary items recorded but had varying amounts of general lexicon available in other databases (28).","[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1016/j.compag.2016.07.028,Computer_Science_292,"Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development.","Advancement in plant phenomics would enable more effective utilization of genetic data, and ultimately lead to novel gene discovery and improved crop yield and quality in the field.","It's a very good problem to have."" Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","It would fill the gap between the low cost of generating large scale datasets of plant genotypes and the time consuming and expensive process of collecting large scale plant phenotypic datasets. Advancement in plant phenomics would enable more effective utilization of genetic data, and ultimately lead to novel gene discovery and improved crop yield and quality in the field. Phenotypic data collected from plants grown in the field is arguably the most informative for guiding plant breeding efforts .","[2.0, 2.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.4,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1177/1080569913501862,Computer_Science_293,"A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region.","As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors.","But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity. A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","One of the more interesting findings was the major gender gap in perceived appropriateness of mobile phone actions. As far as checking text messages, sending text messages, and answering calls, men are nearly twice as accepting of these behaviors. These survey results seem to indicate that women professionals hold different norms of civility as far as mobile phone use during informal meetings.","[1.0, 3.0, 4.0, 2.0, 2.0]",Computer_Science,train,2.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_294,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.","Approximately 63% of the students considered accepting a call during a face-to-face meeting as ""rude.""","Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.","Most shocking to the researchers was the fact that 11% of the students had taken a call during a funeral. Approximately 63% of the students considered accepting a call during a face-to-face meeting as ""rude."" Approximately 62% of these professionals said that using a Blackberry was inappropriate during meetings, and roughly 68% said using an iPhone was inappropriate in meetings.","[4.0, 4.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.6,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Computer_Science_296,"The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved.","Once more, it appears that people praise utilitarian, self-sacrificing AVs, and welcome them on the road, without actually wanting to buy one for themselves.","Or, as the researchers write in the new paper, ""For the time being, there seems to be no easy way to design algorithms that would reconcile moral values and personal self-interest."" The results consistently showed that people will take a utilitarian approach to the ethics of autonomous vehicles, one emphasizing the sheer number of lives that could be saved. For instance, 76 percent of respondents believe it is more moral for an autonomous vehicle, should such a circumstance arise, to sacrifice one passenger rather than 10 pedestrians.","But in terms of purchase intention, it received significantly fewer points than the high-valued algorithm (p < 0.001), and was in fact closer to the low-valued algorithms (median budget share = 33). Once more, it appears that people praise utilitarian, self-sacrificing AVs, and welcome them on the road, without actually wanting to buy one for themselves. This is the classic signature of a social dilemma, in which everyone has a temptation to free-ride instead of adopting the behavior that would lead to the best global outcome.","[4.0, 3.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1287/mnsc.2016.2500,Computer_Science_297,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.",***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1 shares of airlines within each airport as calculated by the number of flights completed.,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","The number of observations used is different from the second dataset sample size due to missing values of Actual-TurnAround-Time, Aircraft-Age and Avg-Passengers variables. ***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1 shares of airlines within each airport as calculated by the number of flights completed. Thus, Southwest Airlines experienced a greater difference in departure delays between the After and Before periods than the other airlines, at the 57 airports.","[2.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.5,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_298,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.","More than three quarters of respondents considered making or answering a call (87.1%), writing and sending texts or emails (84.0%), checking texts or emails (76.0%), and browsing the Internet (75.7%) as rarely or never acceptable in formal meetings.","Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.","Table 3 shows the perceived appropriateness of these various mobile phone behaviors during formal meetings at the workplace. More than three quarters of respondents considered making or answering a call (87.1%), writing and sending texts or emails (84.0%), checking texts or emails (76.0%), and browsing the Internet (75.7%) as rarely or never acceptable in formal meetings. More than half of the respondents stated the remaining four actions were rarely or never acceptable.","[4.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_299,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","""For many travelers, the most odious aspect of the baggage fee is the anticipated battle for overhead-bin space.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","elite frequent flyers, business travelers, those who do not check in bags) are not affected by the fees instituted on one or two checked bags, and thus this customer segment is irrelevant for the purpose of our study. ""For many travelers, the most odious aspect of the baggage fee is the anticipated battle for overhead-bin space. All this will likely get worse, though the airlines say that the new fee won't be collected in airplane cabins from customers who Hypothesis 1a.","[3.0, 1.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_30,The researchers found that people remember information better if it is presented to them in a virtual environment.,This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[3.0, 4.0, 5.0, 5.0]",Computer_Science,train,4.25,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1016/j.neuroimage.2014.02.004,Computer_Science_301,"Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds.","This finding could reflect the involvement of the motor cortex in processing of seen actions ; for a review, see .","Viewing a movie creates multilevel changes in the brain function. Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds. ""The analysis revealed important similarities between brain signals of different people during movie viewing.","Interestingly, the first component in the 1-5 Hz band correlated with activity in the motor cortex in the precentral gyrus. This finding could reflect the involvement of the motor cortex in processing of seen actions ; for a review, see . The MEG signals also showed clear spectral peaks at 12 Hz, 24 Hz, and 36 Hz, i.e.","[2.0, 1.0, 3.0, 1.0, 4.0]",Computer_Science,train,2.2,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1080569913501862,Computer_Science_302,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","On the other hand, strong majorities of employees above 41 years of age consider these actions as inappropriate.","Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.","Strong majorities of younger employees (21 to 30 years old) considered checking text messages and emails, answering calls, and even writing text messages and emails as appropriate. On the other hand, strong majorities of employees above 41 years of age consider these actions as inappropriate. This seems to indicate major generational differences.","[1.0, 3.0, 3.0, 4.0, 4.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_303,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.",The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall. It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace.,"[1.0, 3.0, 2.0, 4.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.neuroimage.2014.02.004,Computer_Science_304,"The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research.","Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie .","These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions. The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research. With the help of MEG and new analysis methods, investigation of significantly faster brain processes is possible and it enables detection of brain activity in frequencies higher than before.","These findings demonstrate the capability of the proposed methodology to uncover cortical MEG signatures from single-trial signals that are consistent across spectators of a movie. Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie . Emotional video clips, compared with non-emotional ones, increase intersubject synchronization of voxel-wise fMRI time courses in many brain areas, for example in the dorsal attention network .","[4.0, 3.0, 1.0, 3.0, 4.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1287/mnsc.2016.2500,Computer_Science_305,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.","When the airlines began charging for two checked bags, we find no significant change in departure performance of legacy carriers, but a degradation of departure performance of low-cost carriers.","The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers. When the airlines began charging for two checked bags, we find no significant change in departure performance of legacy carriers, but a degradation of departure performance of low-cost carriers. These findings indicate that the baggage fees did influence customer behavior, but in the case of charging for both checked bags, not in the direction the airlines had hoped for.","[2.0, 3.0, 3.0, 4.0, 2.0]",Computer_Science,train,2.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1411728112,Computer_Science_306,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.","At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","While macroscopically, only a single second law restricts transitions, we find that there are an entire family of more fundamental restrictions at the quantum level. At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions. What's more, one needs to be more precise about what one means by a cyclic process.","[3.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.5,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1287/mnsc.2016.2500,Computer_Science_308,"The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers.","[2.0, 2.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_311,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","While investigating whether the social planner would let bags fly free, argue that ""baggage fees are not just about revenue.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","However, this test adds support to our Tobit1 regression results. While investigating whether the social planner would let bags fly free, argue that ""baggage fees are not just about revenue. They serve to alter consumer behavior in a manner that is beneficial to both the firm and customers.","[2.0, 2.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1126/science.aaf2654,Computer_Science_314,"Moreover, if autonomous vehicles actually turned out to be safer than regular cars, unease over the dilemmas of regulation ""may paradoxically increase casualties by postponing the adoption of a safer technology.""","Even though people seem to agree that everyone would be better off if AVs were utilitarian (in the sense of minimizing the number of casualties on the road), they all have a personal incentive to ride in AVs that will protect them at all costs.","""This is a challenge that should be on the mind of carmakers and regulators alike,"" the scholars write. Moreover, if autonomous vehicles actually turned out to be safer than regular cars, unease over the dilemmas of regulation ""may paradoxically increase casualties by postponing the adoption of a safer technology."" Empirically informed

The aggregate performance of autonomous vehicles on a mass scale is, of course, yet to be determined.","Our findings suggests that regulation may be necessary, but at the same time counterproductive. Even though people seem to agree that everyone would be better off if AVs were utilitarian (in the sense of minimizing the number of casualties on the road), they all have a personal incentive to ride in AVs that will protect them at all costs. Accordingly, if both selfprotective and utilitarian AVs were allowed on the market, few would be willing to ride in utilitarian AVs, even though they would prefer others to do so.","[3.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1088/1741-2552/aabc9b,Computer_Science_315,"""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr.","We have demonstrated the feasibility of adaptive DBS in PD using a fully implantable device, with feedback control provided by a cortical gamma band oscillation related to the emergence of dyskinesia, a common adverse effect of levodopa therapy and of STN DBS.","An adaptive system like the one being tested here could offer an effective alternative and may also limit adverse effects of traditional deep brain stimulation, but considerable testing remains to be done. ""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr. ""We are now planning larger, longer-term trials to determine how effective this system is in managing the symptoms of patients with Parkinson's disease.""","The zoomed in views of state changes in Figures 3c and 4b indicate that changes in classifier state were appropriately triggered by changes in gamma power. We have demonstrated the feasibility of adaptive DBS in PD using a fully implantable device, with feedback control provided by a cortical gamma band oscillation related to the emergence of dyskinesia, a common adverse effect of levodopa therapy and of STN DBS. While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches.","[5.0, 5.0, 2.0]",Computer_Science,train,5.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1016/j.compag.2016.07.028,Computer_Science_316,The researchers already knew that water-filled plant tissues absorb different wavelengths of light - and absorb the same wavelengths differently - than do their drier counterparts.,This made the thermal IR imaging and the steady state fluorescence imaging module less effective to distinguish maize plants between the two water treatments.,"We were fairly successful in doing that."" The researchers already knew that water-filled plant tissues absorb different wavelengths of light - and absorb the same wavelengths differently - than do their drier counterparts. This allowed them to build a mathematical model that hewed closely to measurements of actual water content, the study reported.",This forced plant leaf temperature and the photosynthetic processes quickly to be in equilibrium with the head house environment (which was significantly different from the greenhouse in terms of temperature and radiation intensity). This made the thermal IR imaging and the steady state fluorescence imaging module less effective to distinguish maize plants between the two water treatments. ET ¼ ½ðW ði;afterÞ À FW i Þ À ðW ðiþ1;beforeÞ À FW iþ1 Þ=T ð1Þ,"[3.0, 2.0, 2.0]",Computer_Science,train,2.333333333333333,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_317,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","The above studies show that compared to a purely mental mnemonic, a graphics desktop setup is better in assisting retention and recall.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","The study found that there was no significant difference between the users' ability to immediately recall the words after a 2-min break, but after one week there was a 25% difference in recall in favor of the 3D graphics desktop memory palace environment condition. The above studies show that compared to a purely mental mnemonic, a graphics desktop setup is better in assisting retention and recall. The study found that higher levels of immersion (in this case, field of view) were more effective in learning complex procedures that reference spatial locations.","[2.0, 2.0, 5.0, 1.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1177/1080569913501862,Computer_Science_318,"Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive.""","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

USC

There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","In an open-ended format, we got some sense of the intensity of some of these comments. Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive."" The intensity of these comments was stronger when talking about what managers do.","[2.0, 2.0, 1.0]",Computer_Science,train,1.6666666666666667,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1177/1080569913501862,Computer_Science_32,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","During formal meetings (see Figure 1) , a majority of younger professionals (21 to 30 years old) consider checking text messages and emails as appropriate.","Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.","Our survey does show the magnitude of this difference in concrete terms. During formal meetings (see Figure 1) , a majority of younger professionals (21 to 30 years old) consider checking text messages and emails as appropriate. In fact, they are more than three times as likely to consider this as appropriate than professionals above 40 years of age.","[5.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Computer_Science_321,"In what feels like a particularly dark period for democracy and during a time of increasingly out-of-control deployment of technology into society, I feel a lesson like this one has given me greater understanding of how we might more appropriately introduce algorithms into society.",Moral algorithms for AVs will need to tackle more intricate decisions than that we have considered in our surveys.,"A month later, a more nuanced picture emerged, one that I think offers insights into how technology can and should provide a platform for interacting with policy--and how policy can reflect a diverse set of inputs generated by the people it affects. In what feels like a particularly dark period for democracy and during a time of increasingly out-of-control deployment of technology into society, I feel a lesson like this one has given me greater understanding of how we might more appropriately introduce algorithms into society. Perhaps it even gives us a picture of what a Democracy 2.0 might look like.","This is a challenge that should be on the mind of carmakers and regulators alike. Moral algorithms for AVs will need to tackle more intricate decisions than that we have considered in our surveys. For example, our scenarios did not feature any uncertainty about decision outcomes, but a collective discussion about moral algorithms will have to tackle the concepts of expected risk, expected value, and blame assignment.","[2.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.5,news,http://ct.moreover.com/?a=37598037254&p=1pl&v=1&x=8McLEcTaeJE34juXGV2oZg
10.1287/mnsc.2016.2500,Computer_Science_322,The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.,"As seen in Table 7 , the other control variables are also statistically significant.","Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year. ""It's not free in an operational sense,"" Arikan says.","Similar to Table 6 , the coefficients for the categorical variables for Origin, Route, Carrier, Month, Day-of-Week, Dep-Time-Block, and Arr-Time-Block are not shown in the interest of space, although they are statistically significant. As seen in Table 7 , the other control variables are also statistically significant. Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_323,"""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says.","If the participants were in the same orientation that they had used during learning, they were able to navigate the environment just as well as those who were physically in the environment.","The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education. ""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says. ""We believe the future of education and innovation will benefit greatly from the use of these new visual technologies.""","However, when the building had two floors, relative view orientation during learning and testing mattered. If the participants were in the same orientation that they had used during learning, they were able to navigate the environment just as well as those who were physically in the environment. However, participants were susceptible to disorientation if their starting-out views were different between their training and testing.","[2.0, 1.0, 4.0, 3.0, 2.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1287/mnsc.2016.2500,Computer_Science_324,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","Our study is the first to show empirically that baggage fees do seem to have influenced customer behavior, and that the effect depends on the type of airline.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Their modeling approach indicates that the way in which airlines have been implementing baggage fees has more direct impact on controlling customer behavior than segmenting customers. Our study is the first to show empirically that baggage fees do seem to have influenced customer behavior, and that the effect depends on the type of airline. Unlike who posit that pricing the baggage separately induces customers to exert effort (i.e., to reduce the volume of checked baggage) and thus lowers the airline's costs, we find that this practice also induces customers to increase the volume of carry-on baggage, which does not lower the airline's costs.","[3.0, 2.0, 5.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2552/aabc9b,Computer_Science_325,"Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation.",Another possibility is that bilateral adaptive stimulation may be necessary for clinical benefit and that this is why we did not see a clinical improvement (since we tested only unilateral adaptive DBS).,"This adaptation of the stimulation is the advance we are trying to make with brain stimulation."" Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation. Researchers saw energy savings of 39 percent and 45 percent in the devices when using the adaptive algorithms.","Indeed, it is possible there could have been a floor effect for dyskinesia in this study since dyskinesia was mild for all conditions (see Table 3 ). Another possibility is that bilateral adaptive stimulation may be necessary for clinical benefit and that this is why we did not see a clinical improvement (since we tested only unilateral adaptive DBS). Another consideration is that our results apply specifically to STN DBS, which is currently the most commonly used target for DBS in PD.","[1.0, 1.0, 3.0, 2.0]",Computer_Science,train,1.75,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1016/j.robot.2015.01.003,Computer_Science_327,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,"A more realistic scenario, in which these manifolds are estimated purely on the basis of unlabelled sensorimotor data, is described in .","Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","Note that the naive agent does not know this Jacobian, and that it is introduced here only to accelerate the simulation. A more realistic scenario, in which these manifolds are estimated purely on the basis of unlabelled sensorimotor data, is described in . A sampling of the 2500 manifolds M i corresponding to the outputs m i is illustrated in Fig.","[3.0, 1.0, 1.0, 4.0, 2.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1287/mnsc.2016.2500,Computer_Science_33,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","A notable exception to the charging for checked bags trend was Southwest Airlines, who turned their resistance to this practice into a ""Bags Fly Free"" marketing campaign.","Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.","A notable exception to the charging for checked bags trend was Southwest Airlines, who turned their resistance to this practice into a ""Bags Fly Free"" marketing campaign. At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag.","[3.0, 5.0, 4.0, 2.0]",Computer_Science,train,2.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_330,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","Ultimately, operations managers need to be involved in the discussions about marketing initiatives such as this one to evaluate the operational impact of marketing initiatives.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","Thus, for a company like Southwest Airlines which has a long history of being one of the best in its industry for operational performance and customer satisfaction, the decision of not charging AirTran Airways' passengers for the first two checked bags appears to be in line with their operational strategy. Ultimately, operations managers need to be involved in the discussions about marketing initiatives such as this one to evaluate the operational impact of marketing initiatives. We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times.","[1.0, 1.0, 2.0, 3.0, 2.0]",Computer_Science,train,1.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/978-3-642-55220-5_1,Computer_Science_331,The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier.,"Until recently all the cases had a sub-exponential complexity of type L(1/3), similar to the factorization problem.","This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms. The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier. Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option.","Until recently all the cases had a sub-exponential complexity of type L(1/3), similar to the factorization problem. For larger values of q that stay below the limit L q k (1/3), our algorithm loses its quasi-polynomial nature, but still surpasses the Function Field Sieve. A first major progress was the realization that the DLP in finite fields can be solved in subexponential time, i.e.","[4.0, 1.0, 3.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1080569913501862,Computer_Science_332,Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.,"Writing and reading text messages or emails followed, with roughly one third of the employees citing these actions as recent examples of disrespectful phone use.","Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","Overwhelmingly, taking or making calls during meetings were the most commonly cited examples, with more than one half of employees who commented about meetings stating they had recently observed this behavior and considered it disrespectful. Writing and reading text messages or emails followed, with roughly one third of the employees citing these actions as recent examples of disrespectful phone use. Roughly one fourth of employees had observed recent examples of employees checking incoming calls or allowing their phones to ring that they thought were rude.","[1.0, 2.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.robot.2015.01.003,Computer_Science_334,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,"Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands.","Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","In particular, knowledge of a metric space enables odometry and SLAM . Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands. Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent.","[2.0, 4.0, 2.0]",Computer_Science,train,2.6666666666666665,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1419704112,Computer_Science_335,"So it seems possible that with the globalisation made possible through the Internet, the English language should be changing at a faster rate than ever before.","We have selected only pairs of languages where the relationships are well established and there is no evidence of replacement or blending of populations, avoiding populations with complicated settlement histories.","So it seems possible that with the globalisation made possible through the Internet, the English language should be changing at a faster rate than ever before. Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""","Similarly we have carefully selected sister pairs with known relationships, whereas a whole-tree approach would require us to make assumptions about the more distant relationships between the ancestral lineages that gave rise to these contemporary populations. We have selected only pairs of languages where the relationships are well established and there is no evidence of replacement or blending of populations, avoiding populations with complicated settlement histories. Thus, the sister-pairs approach represents a conservative approach to the data that minimizes the assumptions that we must make about the history of the languages and the mechanisms of population and language change.","[3.0, 1.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1016/j.robot.2015.01.003,Computer_Science_336,"As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans.",The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs.,"""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to. As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans. Probably none of these.","We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment. The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs. In a sufficiently rich environment, the kernels of these functions correspond uniquely to the spatial configuration of the agent's exteroceptors.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1177/1080569913501862,Computer_Science_337,"But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity.","The authors concluded that although mobile phone use in meetings is becoming more acceptable, it is still generally considered rude, inappropriate, or distracting during most meetings.","But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity. A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","Approximately 63% said that they would not text message during meetings. The authors concluded that although mobile phone use in meetings is becoming more acceptable, it is still generally considered rude, inappropriate, or distracting during most meetings. We found that the literature falls short in several ways in identifying how mobile phone behaviors at meetings are perceived as appropriate or not.","[1.0, 4.0, 2.0, 3.0]",Computer_Science,train,2.5,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_338,"In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.","This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ).","The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","Lastly, place cells in the hippocampus activate in specific spatial locations, independent of orientation, providing an internal representation of the environment . This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ). This study found that the users who used a graphics desktop environment as the basis for their method of loci performed better than those using a mental scene of their choice, and those who were not instructed on a memory strategy did not perform as well as those who were instructed to use the memory strategy.","[3.0, 1.0, 4.0, 2.0, 2.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1287/mnsc.2016.2500,Computer_Science_339,"""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance.","This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees.","""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance. The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","The coefficient for the Bag-Fee indicator variable which indicates one checked bag fee as being implemented, is negative and statistically significant (-1.8701; p<0.0001). This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees. In other words, the airlines that implemented the fee for one checked bag saw their departure performance improve, whereas Southwest Airlines experienced a negative impact on its departure performance.","[2.0, 3.0, 4.0, 3.0, 2.0]",Computer_Science,train,2.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_34,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags. Increased boarding times as a result of baggage fees have financial implications as well.","[3.0, 4.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1411728112,Computer_Science_340,"Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions.","In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered.","In particular, we find a family of free energies which generalise the traditional one, and show that they can never increase. The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions. We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is.","[5.0, 4.0, 3.0, 4.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rstb.2008.0288,Computer_Science_342,"These navigational demands stimulate brain development, concludes a study five years in the making.","In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers.","A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","It may be that with a longer period of retirement, performance on tests such as the Rey Figure would normalize entirely. In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers. Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ).","[3.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_344,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","What's more, one needs to be more precise about what one means by a cyclic process.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions. What's more, one needs to be more precise about what one means by a cyclic process. Here, we show that this is not the case in the microscopic regime, and we therefore needs to talk about ""how cyclic"" a process is when stating the second law.","[2.0, 2.0, 4.0]",Computer_Science,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.compag.2016.07.028,Computer_Science_345,"Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.",Phenotypic data collected from plants grown in the field is arguably the most informative for guiding plant breeding efforts .,"Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","Advancement in plant phenomics would enable more effective utilization of genetic data, and ultimately lead to novel gene discovery and improved crop yield and quality in the field. Phenotypic data collected from plants grown in the field is arguably the most informative for guiding plant breeding efforts . This increased variability renders the detection and quantification of genetic factors influencing phenotype more challenging.","[3.0, 1.0, 4.0, 3.0, 3.0]",Computer_Science,train,2.8,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1098/rstb.2008.0288,Computer_Science_346,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.",This finding was replicated when taxi drivers were compared with bus drivers (Maguire et al.,"In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.",2000) . This finding was replicated when taxi drivers were compared with bus drivers (Maguire et al. 2006a-see figure 3c ; see also Woollett & Maguire in press ).,"[4.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.25,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_347,"Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings.","Roughly two thirds of respondents thought the following actions were rarely or never appropriate: writing and sending text messages or emails (66.3%), answering a call (61.4%), and browsing the Internet (61.4%).","Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude. Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.","Table 4 shows the perceived appropriateness of these various mobile phone behaviors during informal, offsite lunch meetings. Roughly two thirds of respondents thought the following actions were rarely or never appropriate: writing and sending text messages or emails (66.3%), answering a call (61.4%), and browsing the Internet (61.4%). Approximately half of respondents thought checking text messages or emails (53.1%) is rarely or never appropriate.","[4.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.robot.2015.01.003,Computer_Science_348,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,This difference between the active and passive generation of the same sensory experience reflects the importance of the knowledge of motor commands during the acquisition of spatial knowledge.,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","A similar conclusion can be drawn from sensory substitution experiments . This difference between the active and passive generation of the same sensory experience reflects the importance of the knowledge of motor commands during the acquisition of spatial knowledge. From a more philosophical point of view, Poincaré [41] also suggested that the notion of space and displacements should necessarily be rooted in the agent's ability to move.","[2.0, 4.0, 2.0]",Computer_Science,train,2.6666666666666665,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1177/1080569913501862,Computer_Science_351,"""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","In formal meetings, professionals in the West were least accepting of mobile phone use during meetings.","With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages. ""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","Prior to getting the results, we suspected there might be some variation by region. In formal meetings, professionals in the West were least accepting of mobile phone use during meetings. In informal meetings, professionals in the Southwest were least accepting of mobile phone use.","[2.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.5,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_352,Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.,"On the basis of these results, we suggested that learning, representing and using a spatial representation of a highly complex and large-scale environment is a primary function of the posterior hippocampus in humans such that this brain region might adapt structurally to accommodate its elaboration.","With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks. In other words, taxi drivers had plumper memory centers than their peers.","2006a-see figure 3c ; see also Woollett & Maguire in press ). On the basis of these results, we suggested that learning, representing and using a spatial representation of a highly complex and large-scale environment is a primary function of the posterior hippocampus in humans such that this brain region might adapt structurally to accommodate its elaboration. Evidence that this pattern of grey matter volume was acquired from the experience of learning and using the highly complex mental map of London comes from an additional finding.","[3.0, 3.0, 2.0]",Computer_Science,train,2.6666666666666665,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_353,"The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","A notable exception to the charging for checked bags trend was Southwest Airlines, who turned their resistance to this practice into a ""Bags Fly Free"" marketing campaign. At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag.","[2.0, 2.0, 2.0, 4.0, 1.0]",Computer_Science,train,2.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_354,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.",These results indicate that any anticipated change in departure performance due to one checked bag fee policy was not originally captured in airlines' scheduled block times.,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","The coefficient of Bag-Fee corresponding to one checked bag fee is not significant, whereas the coefficient of Bag-Fee corresponding to the first two checked bags fees is negative and statistically significant (-0.3796; p<0.0001), providing partial support for Hypothesis H3b. These results indicate that any anticipated change in departure performance due to one checked bag fee policy was not originally captured in airlines' scheduled block times. The airlines were not able to capture it as they typically schedule the block times about six months in advance that airlines decreased the scheduled block times and, given the longer time span over which the first two checked bags fees policy was implemented, the effect is captured in our results.","[2.0, 3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.compag.2016.07.028,Computer_Science_355,"Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","This would allow the better investigation of genetic basis of WUE, which may be controlled by different genetic factors at different stages of plant development, and upscale WUE of individual plants in the greenhouse to plant communities in the field.","Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","By grouping daily WUE, it is also possible to estimate WUE at particular growth stages along plant's life cycle. This would allow the better investigation of genetic basis of WUE, which may be controlled by different genetic factors at different stages of plant development, and upscale WUE of individual plants in the greenhouse to plant communities in the field. The range of LWC for all 44 destructively sampled plants (combining Stage 1 and 2) is from 68.1 to 92.3%, with a mean of 80.1% and a standard deviation of 8.5%.","[2.0, 2.0, 3.0, 1.0]",Computer_Science,train,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_356,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","The study found that when the building was a single floor, the real-world and virtual-environmenttrained users had comparable results.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","This suggests that memory was only enhanced for those aspects of the environment that were interacted with directly-particularly the environment which was navigated. The study found that when the building was a single floor, the real-world and virtual-environmenttrained users had comparable results. However, when the building had two floors, relative view orientation during learning and testing mattered.","[3.0, 1.0, 1.0, 3.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_357,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.",-Hypothesis 1: The participant memory recall accuracy will be higher in the HMD condition as compared to the desktop condition due to the increased immersion.,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",Virtual environments that mirror the scene of the crime could provide superior assistance in recall by placing the victim back into such an environment. -Hypothesis 1: The participant memory recall accuracy will be higher in the HMD condition as compared to the desktop condition due to the increased immersion. -Hypothesis 2: Participants will have higher confidence in their answers in the HMD condition as compared to the desktop condition.,"[2.0, 4.0, 2.0, 1.0, 3.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1098/rstb.2008.0288,Computer_Science_358,And MRIs showed that the successful trainees' hippocampi had grown over time.,"On the basis of these results, we suggested that learning, representing and using a spatial representation of a highly complex and large-scale environment is a primary function of the posterior hippocampus in humans such that this brain region might adapt structurally to accommodate its elaboration.","When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier. And MRIs showed that the successful trainees' hippocampi had grown over time. The successful trainees did not perform better on all tests of memory, however.","2006a-see figure 3c ; see also Woollett & Maguire in press ). On the basis of these results, we suggested that learning, representing and using a spatial representation of a highly complex and large-scale environment is a primary function of the posterior hippocampus in humans such that this brain region might adapt structurally to accommodate its elaboration. Evidence that this pattern of grey matter volume was acquired from the experience of learning and using the highly complex mental map of London comes from an additional finding.","[2.0, 5.0, 5.0, 3.0, 2.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_360,"Most sous vide cooking temperatures are below 190 degrees F (87.8 degrees C), so you shouldn't need to worry about melting.","Because of limited space, only some of the biological hazards for sous vide cooking and their controls are discussed below:","High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures. Most sous vide cooking temperatures are below 190 degrees F (87.8 degrees C), so you shouldn't need to worry about melting.","gives a comprehensive and detailed application of the HACCP-system to refrigerated sous vide products. Because of limited space, only some of the biological hazards for sous vide cooking and their controls are discussed below: Vacuum packaging doesn't reduce the microorganisms, so you must either return it to the refrigerator or freezer or (in most cases) begin cooking immediately in a temperature controlled water bath.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1177/1080569913501862,Computer_Science_361,"Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.",We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West.,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude. Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings.",A possible explanation for more sensitivity to mobile phone use in the Southwest may be the emphasis on hospitality and manners. We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West. We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings.,"[3.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1088/1741-2552/aabc9b,Computer_Science_363,"""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr.","While this cortical detection strategy does require insertion of a subdural lead for motor cortex recording, insertion of this ""extra"" lead is technically simple and can be done at the same time as insertion of the DBS leads, using the same skull opening and surgical exposure as used for the DBS leads .","An adaptive system like the one being tested here could offer an effective alternative and may also limit adverse effects of traditional deep brain stimulation, but considerable testing remains to be done. ""Here we have demonstrated the feasibility of adaptive deep brain stimulation,"" said Dr. Starr. ""We are now planning larger, longer-term trials to determine how effective this system is in managing the symptoms of patients with Parkinson's disease.""","We have demonstrated the technical feasibility of this approach within a totally implanted device. While this cortical detection strategy does require insertion of a subdural lead for motor cortex recording, insertion of this ""extra"" lead is technically simple and can be done at the same time as insertion of the DBS leads, using the same skull opening and surgical exposure as used for the DBS leads . Additionally, the insertion of this lead has not been associated with negative outcomes when used acutely or chronically (in a small sample) .","[5.0, 1.0, 1.0, 2.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1073/pnas.1411728112,Computer_Science_364,"""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","What's more, one needs to be more precise about what one means by a cyclic process.","In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions. What's more, one needs to be more precise about what one means by a cyclic process. Here, we show that this is not the case in the microscopic regime, and we therefore needs to talk about ""how cyclic"" a process is when stating the second law.","[3.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/s10055-018-0346-3,Computer_Science_365,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.",We note that participants could have used personal mnemonics to help remember the locations and ordering of faces.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","According to , the information in the short-term memory decays and is lost within a period of 15-30 s. We feel confident that having participants recall 21 faces after a 2-min break will engage their longterm memory. We note that participants could have used personal mnemonics to help remember the locations and ordering of faces. However, since we evaluated recall for each participant over a desktop and a HMD, their performance should be counterbalanced between the two display conditions.","[3.0, 1.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1098/rstb.2008.0288,Computer_Science_366,"These navigational demands stimulate brain development, concludes a study five years in the making.","Moreover, the amount of medical experience, which ranged from 0.5 to 22.5 years, did not correlate with grey matter volume in the hippocampus or elsewhere in the brain.","A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","VBM analysis failed to identify any differences in grey matter volume between the groups, including in the hippocampus. Moreover, the amount of medical experience, which ranged from 0.5 to 22.5 years, did not correlate with grey matter volume in the hippocampus or elsewhere in the brain. From this, we conclude that intensively acquiring a large amount of knowledge over many years is not invariably associated with structural brain differences.","[1.0, 2.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_367,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is.","Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions. We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is. In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state.","[1.0, 2.0, 2.0, 2.0]",Computer_Science,train,1.75,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/s10055-018-0346-3,Computer_Science_368,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.","9 show that when the users were less error-prone in the HMD condition, their confidence was better-grounded in the recall accuracy than when in the desktop condition.","Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","The results in Fig. 9 show that when the users were less error-prone in the HMD condition, their confidence was better-grounded in the recall accuracy than when in the desktop condition. In general, participants were more often correct in the HMD condition than for the desktop condition for a given confidence level.","[2.0, 3.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.8,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_369,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","Thus, the implementation of checked bag fees (a marketing decision) provides an ideal setting to study how an industry changed, or coordinated, their operations to respond to this marketing strategy change. Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","[2.0, 3.0, 4.0, 1.0, 3.0]",Computer_Science,train,2.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_37,Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.,"The differences between women and men were quite striking, with men nearly twice as likely to consider various mobile phone behaviors as acceptable in informal meetings.","Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","There were significant differences by age, group, gender, region, and income level. The differences between women and men were quite striking, with men nearly twice as likely to consider various mobile phone behaviors as acceptable in informal meetings. Among Gen Y (18 to 29 years old) and Gen X (30 to 49 years old) adults, mobile phone ownership is 94% and 90%, respectively ).","[5.0, 5.0, 5.0, 4.0, 3.0]",Computer_Science,train,4.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_370,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","elite frequent flyers, business travelers, those who do not check in bags) are not affected by the fees instituted on one or two checked bags, and thus this customer segment is irrelevant for the purpose of our study.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","The passengers can also check more than two bags, however these extra-bags have always incurred additional fees, thus our discussion reduces to their behavior regarding the first two checked bags. elite frequent flyers, business travelers, those who do not check in bags) are not affected by the fees instituted on one or two checked bags, and thus this customer segment is irrelevant for the purpose of our study. ""For many travelers, the most odious aspect of the baggage fee is the anticipated battle for overhead-bin space.","[2.0, 3.0, 2.0]",Computer_Science,train,2.333333333333333,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_371,"These navigational demands stimulate brain development, concludes a study five years in the making.",This accords with the findings across species that there may be functional differentiation along the anterior-posterior axis of the hippocampus (e.g.,"A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.",We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume. This accords with the findings across species that there may be functional differentiation along the anterior-posterior axis of the hippocampus (e.g. 2000; .,"[2.0, 1.0, 2.0, 2.0]",Computer_Science,train,1.75,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_372,"Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","For the most part, this research indicates that using mobile devices leads to multitasking with minimal or negative impacts on individual and team productivity .","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

USC

There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Among Gen Y (18 to 29 years old) and Gen X (30 to 49 years old) adults, mobile phone ownership is 94% and 90%, respectively ). For the most part, this research indicates that using mobile devices leads to multitasking with minimal or negative impacts on individual and team productivity . As a result, they increase their levels of productivity, performance, and outreach by staying in touch with their clientele base, which in turn increases responsiveness and profit margins.","[4.0, 2.0, 2.0, 2.0, 1.0]",Computer_Science,train,2.2,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1016/j.neuroimage.2014.02.004,Computer_Science_373,"These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions.","Moreover, canonical variates were associated with source currents in the posterior parietal cortex (PPC), the superior temporal sulci (STS), and the prefrontal cortex (PFC).","""The analysis revealed important similarities between brain signals of different people during movie viewing. These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions. The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research.","Relatively high correlations in posterior brain regions agree with the conjecture that these areas belong to extrinsic brain networks that are most directly driven by visual stimuli. Moreover, canonical variates were associated with source currents in the posterior parietal cortex (PPC), the superior temporal sulci (STS), and the prefrontal cortex (PFC). PPC activity occurred in frequency bands of 0.03-1 and 1-5 Hz.","[2.0, 1.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.neuroimage.2014.02.004,Computer_Science_374,Viewing a movie creates multilevel changes in the brain function.,"Some canonical variates that did not survive our correlation threshold still pinpointed distinct brain areas, typically in the early visual cortices.","By employing movies it was possible to investigate the function of the human brain in experimental conditions that are close to natural. Viewing a movie creates multilevel changes in the brain function. Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds.","1 ), implying that they do not reflect just signal power. Some canonical variates that did not survive our correlation threshold still pinpointed distinct brain areas, typically in the early visual cortices. 5 shows a functionally feasible correlation map involving visual cortices for the first canonical variate in the 5-10 Hz band; the correlation values had not exceeded our significance level (see Fig.","[2.0, 1.0, 3.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_375,"Well, yeah, if you subject them to high temperatures.","The type of fat used to sear the meat in a pan has only minor effects on the formation of mutagens, but the pan residue using butter was significantly higher in mutagens than when using vegetable oil .","High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures. Most sous vide cooking temperatures are below 190 degrees F (87.8 degrees C), so you shouldn't need to worry about melting.","While adding glucose increases browning, it can decrease the production of mutagens . The type of fat used to sear the meat in a pan has only minor effects on the formation of mutagens, but the pan residue using butter was significantly higher in mutagens than when using vegetable oil . • C/3 500 • F in air, and produce a particularly nice crust on beef; Baldwin (2008) and recommend using a butane blowtorch since propane can leave an off-flavor.","[2.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.75,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1007/978-3-642-55220-5_1,Computer_Science_377,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,"However, in almost the whole range of applicability of the Function Field Sieve algorithm, our algorithm is asymptotically better than FFS.","Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","If the characteristic of the base field is not so small compared to the extension degree, the complexity of our algorithm does not keep its nice quasi-polynomial form. However, in almost the whole range of applicability of the Function Field Sieve algorithm, our algorithm is asymptotically better than FFS. The condition can then be rewritten as log q = O((log Q) α (log log Q) 1−α ) and therefore k = log Q/ log q = O((log Q/ log log Q) 1−α ).","[1.0, 3.0, 3.0, 1.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/978-3-642-55220-5_1,Computer_Science_379,"This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms.","It makes no sense, therefore, to use the descent procedure beyond this point, as the recovery of discrete logarithms of all these polynomials is better achieved as a pre-computation.","Not only is it significantly easier to explain, but its complexity is also considerably improved. This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms. The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier.","Because of the arity of the descent tree, the breadth eventually exceeds the number of polynomials below some degree bound. It makes no sense, therefore, to use the descent procedure beyond this point, as the recovery of discrete logarithms of all these polynomials is better achieved as a pre-computation. In our case, we could in principle go up to degree O(log q) without changing the complexity.","[2.0, 1.0, 4.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Computer_Science_38,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","These effects can be positive and negative, with increased expertise and grey matter volume in some brain regions occurring in tandem with decreased performance on other tasks and decreased grey matter volume in neighbouring brain areas. Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition.","[3.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.75,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_382,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.","***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1 the likelihood of lack of overhead space, which in turn leads to ""bags that need to be checked at the last minute -a common cause of delayed flights.""","The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","The number of observations used is different from the dataset sample size due to missing values of Aircraft-Age, Avg-Passengers, Origin-Prcp, Dest-Prcp, Origin-Awnd, and Dest-Awnd variables. ***p < 0.0001; **p < 0.01; *p < 0.05; + p < 0.1 the likelihood of lack of overhead space, which in turn leads to ""bags that need to be checked at the last minute -a common cause of delayed flights."" On the other hand, Table 9 shows negative coefficients of the same variable, and thus indicates that American Airlines, Continental Airlines, Delta Airlines, Northwest Airlines, United Airlines, and US Airways passengers were less price sensitive and did not change their behavior to carry on more bags as the low-cost carriers customers appear to have.","[1.0, 3.0, 2.0, 1.0]",Computer_Science,train,1.75,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.robot.2015.01.003,Computer_Science_383,"These low-probability events may be used by the brain to construct general perceptual notions.""",Note that to obtain this internal representation the agent does not have to assume the existence of space: it simply has to associate the motor commands resulting in the same sensory input with each other.,"""This property seems miraculous if you think about how many receptors the human body has,"" Terekhov said. These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""",It can therefore be used as an internal representation of the agent's external configuration. Note that to obtain this internal representation the agent does not have to assume the existence of space: it simply has to associate the motor commands resulting in the same sensory input with each other. The notion of space is thus a byproduct of the agent's drive to capture its sensorimotor experience in a compact way.,"[1.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1098/rspb.2019.0646,Computer_Science_384,"***EMBARGOED UNTIL 7:01 P.M. May 14 EDT ***

FOR IMMEDIATE RELEASE

CONTACT: Kathleen Haughney, University Communications

(850) 644-1489; khaughney@fsu.edu

@FSUResearch

May 2019

IN GUPPY COURTSHIP, THE UNUSUAL MALE WINS

New FSU Study Shows Psychological Concept Underpins Mating Choices

Newswise -- TALLAHASSEE, Fla. -- When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns.",B 286: 20190646 games is an important next step.,"***EMBARGOED UNTIL 7:01 P.M. May 14 EDT ***

FOR IMMEDIATE RELEASE

CONTACT: Kathleen Haughney, University Communications

(850) 644-1489; khaughney@fsu.edu

@FSUResearch

May 2019

IN GUPPY COURTSHIP, THE UNUSUAL MALE WINS

New FSU Study Shows Psychological Concept Underpins Mating Choices

Newswise -- TALLAHASSEE, Fla. -- When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns. Turns out, it's all about psychology. In other words, the female guppy is often immune to the charms of a male guppy that looks like all the other male guppies.","If travel time between patches is long, specialization should be favoured (top); if travel time between patches is short, a generalist strategy instead minimizes the intake rate of predators (bottom). B 286: 20190646 games is an important next step. For example, predators with inferior acuity may see two backgrounds as being more similar, making generalism a more effective strategy.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39225183970&p=1pl&v=1&x=kt9epreGa8FUuUQ7RXzVww
10.1007/s10055-018-0346-3,Computer_Science_385,Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training.,"The study found that higher levels of immersion (in this case, field of view) were more effective in learning complex procedures that reference spatial locations.","Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","The above studies show that compared to a purely mental mnemonic, a graphics desktop setup is better in assisting retention and recall. The study found that higher levels of immersion (in this case, field of view) were more effective in learning complex procedures that reference spatial locations. In addition, there was no statistical difference in performance for the simple task for the different levels of immersion.","[3.0, 4.0, 4.0, 4.0, 5.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1177/1080569913501862,Computer_Science_386,"Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate.","Table 4 shows the perceived appropriateness of these various mobile phone behaviors during informal, offsite lunch meetings.","87 percent of people said answering a call was rarely or never acceptable in business meetings. Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.","More than half of the respondents stated the remaining four actions were rarely or never acceptable. Table 4 shows the perceived appropriateness of these various mobile phone behaviors during informal, offsite lunch meetings. Roughly two thirds of respondents thought the following actions were rarely or never appropriate: writing and sending text messages or emails (66.3%), answering a call (61.4%), and browsing the Internet (61.4%).","[4.0, 5.0, 5.0, 3.0, 3.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1287/mnsc.2016.2500,Computer_Science_388,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","When the other airlines began charging for the first two checked bags, however, Southwest's decision appears to be in line with their strategy.","Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","When the other airlines started charging for one checked bag, Southwest Airlines' decision to not charge for bags went against their high operational service level strategy as their relative departure delay performance initially decreased. When the other airlines began charging for the first two checked bags, however, Southwest's decision appears to be in line with their strategy. While bags may not really ""fly free"" in an operational sense at Southwest, not charging passengers for checking bags does seem to help avoid the worst carry-on abuses seen at other airlines that have led to a degradation of on-time departure performance.","[2.0, 2.0, 2.0, 4.0]",Computer_Science,train,2.5,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_389,"In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",This makes it possible to compare recall for the same user across the two display modalities.,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable--and adept--in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","In this inspirational study, the participants only experienced one display. This makes it possible to compare recall for the same user across the two display modalities. The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1007/s10055-018-0346-3,Computer_Science_39,They found that people remember information better if it is presented to them in a virtual environment.,"If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.","Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.","[3.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.25,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_391,"""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance.",We also identify the differential impact of baggage fees on 'low-cost' versus 'legacy' carriers: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers when charging for one checked bag.,"""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance. The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag. We also identify the differential impact of baggage fees on 'low-cost' versus 'legacy' carriers: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers when charging for one checked bag. When the airlines began charging for two checked bags, we find no significant change in departure performance of legacy carriers, but a degradation of departure performance of low-cost carriers.","[4.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_392,"The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases.","The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag. The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers.","Hence, given the previously hypothesized departure performances (i.e. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time decreases.","[5.0, 3.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.neuroimage.2014.02.004,Computer_Science_393,Viewing a movie creates multilevel changes in the brain function.,"STS involvement was to be expected because of the multitude of social stimuli and biological motion in the movie (for a review, see .","By employing movies it was possible to investigate the function of the human brain in experimental conditions that are close to natural. Viewing a movie creates multilevel changes in the brain function. Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds.","Intersubject correlations occurred in the STS region bilaterally and they were most prominently related to the first three canonical variates in the lowest, 0.03-1-Hz band. STS involvement was to be expected because of the multitude of social stimuli and biological motion in the movie (for a review, see . The canonical variates in 0.03-1 Hz band included activity in PFC that could reflect emotional engagement to the movie .","[3.0, 3.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1088/1741-2552/aabc9b,Computer_Science_394,"Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers.","Although this approach has shown promise 1,2 , the STN LFP is a low amplitude signal that is strongly affected by stimulation artifact when stimulation is delivered on adjacent contacts.","Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects. Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.","The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded. Although this approach has shown promise 1,2 , the STN LFP is a low amplitude signal that is strongly affected by stimulation artifact when stimulation is delivered on adjacent contacts. Indeed, for our particular control strategy (using a narrowband gamma feedback signal), the signal was more reliably detected in cortex compared to STN both on and off DBS ( Figure 5 ).","[1.0, 1.0, 2.0, 2.0]",Computer_Science,train,1.5,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1287/mnsc.2016.2500,Computer_Science_395,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.",Their modeling approach indicates that the way in which airlines have been implementing baggage fees has more direct impact on controlling customer behavior than segmenting customers.,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.","Our study contributes to this research stream by including a new possible factor that influences departure delays, i.e. Their modeling approach indicates that the way in which airlines have been implementing baggage fees has more direct impact on controlling customer behavior than segmenting customers. Our study is the first to show empirically that baggage fees do seem to have influenced customer behavior, and that the effect depends on the type of airline.","[3.0, 2.0, 3.0]",Computer_Science,train,2.6666666666666665,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_396,They found that people remember information better if it is presented to them in a virtual environment.,This makes it possible to compare recall for the same user across the two display modalities.,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","In this inspirational study, the participants only experienced one display. This makes it possible to compare recall for the same user across the two display modalities. The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop.","[3.0, 1.0, 2.0, 1.0, 3.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1016/j.robot.2015.01.003,Computer_Science_397,"""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","However, our approach differs from a large part of this literature by not assuming the pre-coding of building blocks or any processing of the sensory flow.","""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said. ""We believe that the principles introduced by Poincare, which are the basis of our algorithms, could be more general and are utilized by the brain at multiple levels.","Indeed, the notion of space is intimately related to the agent's ability to move [41] . However, our approach differs from a large part of this literature by not assuming the pre-coding of building blocks or any processing of the sensory flow. Our work adds to existing research by making explicit what properties of the raw sensorimotor flow can lead an agent to perceive space.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1419704112,Computer_Science_398,"Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar.","Our analyses revealed two significant patterns in the data: languages that had larger speaker populations tended to have higher rates of gain of new words in basic vocabulary than their smaller sister languages, and smaller populations tended to have higher rates of word loss from basic vocabulary (Table 1 and Fig.","So it seems possible that with the globalisation made possible through the Internet, the English language should be changing at a faster rate than ever before. Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""","The models varied in (i) whether the data were phylogenetically structured or not, (ii) whether new populations rapidly achieved a stable population size upon colonizing a new area, or underwent a more protracted period of growth, (iii) whether new languages formed by an allopatric process, where a parent population underwent fission to produce two daughter populations, or by a peripatric process, where the parent population gave rise to a daughter population by a process of colonization, and (iv) whether or not new languages experienced a founder effect, losing a number of words when a new population became established (Methods). Our analyses revealed two significant patterns in the data: languages that had larger speaker populations tended to have higher rates of gain of new words in basic vocabulary than their smaller sister languages, and smaller populations tended to have higher rates of word loss from basic vocabulary (Table 1 and Fig. Variation in population size explained about 10-20% of the variation in word gains and losses (Table 1) .","[3.0, 3.0, 4.0, 4.0]",Computer_Science,train,3.5,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1287/mnsc.2016.2500,Computer_Science_399,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Using over 27,000 monthly route observations between 1997 to 2000, find that less competitive routes are characterized by lower service quality, in terms of both more frequent and longer flight delays.","Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays. Using over 27,000 monthly route observations between 1997 to 2000, find that less competitive routes are characterized by lower service quality, in terms of both more frequent and longer flight delays. Further, as hub origin, vertical integration with regional partners to operate flights, and Internet access on departure delays, but these factors are not relevant for our objective.","[1.0, 2.0, 1.0]",Computer_Science,train,1.3333333333333333,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_40,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","In informal meetings, professionals in the Southwest were least accepting of mobile phone use.","Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","In formal meetings, professionals in the West were least accepting of mobile phone use during meetings. In informal meetings, professionals in the Southwest were least accepting of mobile phone use. A possible explanation for more sensitivity to mobile phone use in the Southwest may be the emphasis on hospitality and manners.","[3.0, 4.0, 4.0, 5.0, 4.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1111/jcc4.12109,Computer_Science_400,"The team writes: ""The researchers found a significant increase in anxiety, heart rate and blood pressure levels, and a significant decrease in puzzle performance when the participants were separated from their iPhones as compared to when iPhone users completed similar word search puzzles while in possession of their iPhones.""","In contrast, when participants completed word-search puzzles with their iPhone in their possession, heart rate and blood pressure levels returned to baseline and cognitive performance increased.","Additionally, the results from our study suggest that iPhones are capable of becoming an extension of our selves such that when separated, we experience a lessening of 'self' and a negative physiological state."" The team writes: ""The researchers found a significant increase in anxiety, heart rate and blood pressure levels, and a significant decrease in puzzle performance when the participants were separated from their iPhones as compared to when iPhone users completed similar word search puzzles while in possession of their iPhones."" The findings underpin just how addicted we've become to technology.","It is interesting to note that self-reported feelings of unpleasantness and anxiety reflected participants' physiological responses such that perceived levels of unpleasantness and anxiety were greatest during iPhone separation. In contrast, when participants completed word-search puzzles with their iPhone in their possession, heart rate and blood pressure levels returned to baseline and cognitive performance increased. Again, self-reported feelings of unpleasantness and anxiety reflected participants' physiological responses such that perceived levels of unpleasantness and anxiety were lowest when participants were in possession of their iPhone.","[5.0, 4.0, 5.0, 4.0]",Computer_Science,train,4.5,news,http://www.businessinsider.com/being-away-from-your-iphone-causes-psychological-problems-2015-1
10.1073/pnas.1821667116,Computer_Science_401,"""One might expect the many factors absent from the taxi drive process - variations in street segment lengths and driving speeds, taxi-taxi interactions, human routing decisions, passenger pickup and drop-off times and locations - would play a role in the statistical properties of taxis,"" the authors wrote.","One might expect the many factors absent from the urban explorer process -variations in street segment lengths and driving speeds, taxi-taxi interactions, human routing decisions, heterogeneities in passenger pickup and dropoff times and locations -would play a role in the statistical properties of real taxis.","This likely contributes to the similar patterns researchers found when they applied their model to other cities, including San Francisco, Chicago, Vienna, Singapore and the Chinese cities Yangpu, Beijing, Changsha, Hangzhou and Shanghai. ""One might expect the many factors absent from the taxi drive process - variations in street segment lengths and driving speeds, taxi-taxi interactions, human routing decisions, passenger pickup and drop-off times and locations - would play a role in the statistical properties of taxis,"" the authors wrote. ""Yet our results show that, at the macroscopic level ... these complexities are unimportant.""","This good agreement is surprising. One might expect the many factors absent from the urban explorer process -variations in street segment lengths and driving speeds, taxi-taxi interactions, human routing decisions, heterogeneities in passenger pickup and dropoff times and locations -would play a role in the statistical properties of real taxis. Yet our results show that, at the macroscopic level of segment popularity distributions, these complexities are unimportant.","[5.0, 5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://ct.moreover.com/?a=39437526803&p=1pl&v=1&x=36u7Ed6XZixj9HLQ5eZ_Nw
10.1509/jppm.14.112,Computer_Science_403,The researchers compared the calorie content of the ordered lunches and found that each label reduced the calories ordered by 10 percent.,Each label type reduced lunch calories by approximately 10%.,"Published in the Journal of Public Policy Marketing, the results from the study -- the first online food ordering field experiment -- suggest that consumers benefit from easier to understand information about what is, and isn't, a healthy food choice. The researchers compared the calorie content of the ordered lunches and found that each label reduced the calories ordered by 10 percent. ""Calorie labeling appears to be effective in an online environment where consumers have fewer distractions, and the simpler traffic-light labeling seems as effective as standard calorie numbers,"" said Eric M. Van Epps, a 2015 CMU alumnus who is a postdoctoral researcher at the University of Pennsylvania's Perelman School of Medicine.","Each label type reduced lunch calories by approximately 10%. Nutrition knowledge was not improved by any menu format. Traffic light labels achieved meaningful reductions in calories ordered even in the absence of numeric information, and the authors found no apparent benefit or detriment of combining label types.","[5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://healthmedicinet.com/news/traffic-lights-calorie-counts-help-consumers-order-healthier-online/
10.1016/j.neuroimage.2013.06.064,Computer_Science_404,"Notable, areas in the medial orbitofrontal region and the anterior cingulate cortex, which are relevant for self-referential appraisal and aesthetic judgments, were found to be activated during the listening.","Notably, activations in the medial orbitofrontal region and the anterior cingulate cortex, relevant for self-referential appraisal and aesthetic judgments, could be predicted successfully.","The study revealed that activations in several areas in the brain belonging to the auditory, limbic, and motor regions were activated by all musical pieces. Notable, areas in the medial orbitofrontal region and the anterior cingulate cortex, which are relevant for self-referential appraisal and aesthetic judgments, were found to be activated during the listening. A further interesting finding was that vocal and instrumental music were processed differently.","Individual models for the two musical medleys revealed that activations in several areas in the brain belonging to the auditory, limbic, and motor regions could be predicted. Notably, activations in the medial orbitofrontal region and the anterior cingulate cortex, relevant for self-referential appraisal and aesthetic judgments, could be predicted successfully. Cross-validation across musical stimuli and participant pools helped identify a region of the right superior temporal gyrus, encompassing the planum polare and the Heschl's gyrus, as the core structure that processed complex acoustic features of musical pieces from various genres, with or without lyrics.","[3.0, 4.0, 4.0, 4.0]",Computer_Science,train,3.75,news,http://www.sciencedaily.com/releases/2013/08/130807094348.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1145/3171221.3171276,Computer_Science_405,"When the researchers evaluated different similarity measures, they found that one in particular generalized well to a broad range of tasks, producing expressive motions that are tailored to individual tasks.","We introduce and evaluate candidate similarity measures, and show that one in particular generalizes to a range of tasks, while producing expressive motions that are tailored to each task.","Their approach minimizes the similarity between the motion expressing incapability and what would allow the robot to successfully execute the task, while also considering the physical limitations of the robot. When the researchers evaluated different similarity measures, they found that one in particular generalized well to a broad range of tasks, producing expressive motions that are tailored to individual tasks. The method employed by the researchers automatically generates motions that express robot incapability, communicating both what it is trying to achieve and the reasons behind its failure.","We introduce and evaluate candidate similarity measures, and show that one in particular generalizes to a range of tasks, while producing expressive motions that are tailored to each task. Our user study supports that our approach automatically generates motions expressing incapability that communicate both what and why to end-users, and improve their overall perception of the robot and willingness to collaborate with it in the future. There are two relevant pieces of information when expressing incapability: what the task is, and why the robot is incapable of accomplishing it.","[5.0, 5.0, 5.0, 3.0, 5.0]",Computer_Science,train,4.6,news,http://ct.moreover.com/?a=37562557218&p=1pl&v=1&x=4ochmWTdyZuTipvHkRof4g
10.1089/cyber.2017.0466,Computer_Science_406,"Given these substantial costs and limitations, it is noteworthy that there is little consistent evidence that filtering is effective at shielding young people from online sexual material.",This delivered conclusive evidence that filters were not effective for protecting young people from online sexual material.,"The UK would join countries around the world who filter the public Internet for religious or political reasons. Given these substantial costs and limitations, it is noteworthy that there is little consistent evidence that filtering is effective at shielding young people from online sexual material. The researchers ""found that Internet filtering tools are ineffective and in most cases [and] were an insignificant factor in whether young people had seen explicit sexual content.""","Our confirmatory analyses, based on 2018 data from the United Kingdom, provided a more rigorous test of filtering effects. This delivered conclusive evidence that filters were not effective for protecting young people from online sexual material. The findings speak to the mixed results in the existing literature and suggest that both positive and null effects observed for filtering might be partially accurate.","[4.0, 4.0, 5.0, 3.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34536388508&p=1pl&v=1&x=g5czjrsEN6ThRIV5hnfNRA
10.1145/2998181.2998213,Computer_Science_407,"If we allow people to retract recently posted comments, then we may be able to minimize regret from posting in the heat of the moment.",Allowing users to retract recently posted comments may help minimize regret .,"Social interventions can also reduce trolling. If we allow people to retract recently posted comments, then we may be able to minimize regret from posting in the heat of the moment. Altering the context of a discussion, by prioritizing constructive comments, can increase the perception of civility.","However, not only are some banned users likely to be ordinary users just having a bad day, but such an approach also does little to curb such situational trolling, which many ordinary users may be susceptible to. Allowing users to retract recently posted comments may help minimize regret . Alternatively, reducing other sources of user frustration (e.g., poor interface design or slow loading times ) may further temper aggression.","[5.0, 5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://ct.moreover.com/?a=39159803736&p=1pl&v=1&x=CjCQObineQ6jrrt2HGSVLw
10.1177/2053951719842540,Computer_Science_408,"If the social network continues to grow at its current rate of 13% a year, the number of dead profiles on Facebook will reach 4.9 billion by the end of the century.","The results should be interpreted not as a prediction of the future, but as a commentary on the current development, and an opportunity to shape what future we are headed towards.","And that's just based on current Facebook membership numbers. If the social network continues to grow at its current rate of 13% a year, the number of dead profiles on Facebook will reach 4.9 billion by the end of the century. But the authors say that landmark isn't what's important.","Our projection of growth in dead Facebook users' accounts marks the first step toward empirically exploring the macroscopic and quantitative aspects of death on social media. The results should be interpreted not as a prediction of the future, but as a commentary on the current development, and an opportunity to shape what future we are headed towards. Beside the formalized uncertainty of the model discussed above, there is also a non-quantifiable uncertainty regarding the data underlying the model.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39105938267&p=1pl&v=1&x=PcPhCtJdwehlMzLbrDknAw
10.1016/j.neuroimage.2018.06.031,Computer_Science_409,Changes in communication between the brain's cortical areas could also be related to cognitive impairments correlated with cannabis use.,A decrease in posterior network degree and an increase in the clustering coefficient in frontal regions suggests changes in long-range communications that allow for corticocortical interactions between networks and may be related to cognitive impairments associated with cannabis use.,"Prashad said this could signify that participants had difficulty inhibiting neural activity that has been observed in Dr. Filbey's previous studies, which would cause them to exert more effort as they attempted to stop doing certain tasks. Changes in communication between the brain's cortical areas could also be related to cognitive impairments correlated with cannabis use. The findings of this research suggest that further studies are needed during task-related activity for comparison, Prashad said.","This loss of neural refinement indicates a noisy brain and an impairment in inhibiting ongoing neural activity that may interrupt cognitive processing. A decrease in posterior network degree and an increase in the clustering coefficient in frontal regions suggests changes in long-range communications that allow for corticocortical interactions between networks and may be related to cognitive impairments associated with cannabis use. Significant correlations were found between cannabis use measures and spectral power and functional connectivity, highlighting electrophysiological signals as relevant neural associations that may be essential in examining effects related to cannabis use.","[4.0, 4.0, 3.0, 5.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=37015437988&p=1pl&v=1&x=_bndVHW_sBM9fGcso8ytdA
10.1177/1080569913501862,Computer_Science_41,"""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","Not surprisingly, younger professionals are more accepting of mobile phone use.","With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages. ""Not surprisingly, millennials and younger professionals were more likely to be accepting of smartphone use, but they might be doing themselves a disservice,"" Cardon said.","Based on the findings, we have made several basic conclusions. Not surprisingly, younger professionals are more accepting of mobile phone use. Interestingly, women are far less accepting of mobile phone use during informal meetings.","[5.0, 5.0, 5.0, 5.0]",Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/srep07236,Computer_Science_410,The research demonstrated that NPP is able to significantly outperform the current state-of-the-art methods in predicting node degree centrality.,The empirical experiments reveal that NPP is able to provide more precise prediction of node's future degree centrality over baseline solutions.,"""Our method has wide range of applications in critical human systems, such as financial markets and military operations."" The research demonstrated that NPP is able to significantly outperform the current state-of-the-art methods in predicting node degree centrality. ""Our method, NPP, is helpful in the prediction of an individual's future importance because it reconciles the trade-offs between two important principles that drive the evolution of social networks -- preferential attachment and triadic closure,"" Chawla said.","Triad 3 is a stable sub-structure , as the propensity of attaching new links for the nodes having high occurrence frequencies in position 5 is relatively small. The empirical experiments reveal that NPP is able to provide more precise prediction of node's future degree centrality over baseline solutions. NPP is validated on four different social networks.","[5.0, 4.0, 5.0, 5.0]",Computer_Science,train,4.75,news,http://www.sciencedaily.com/releases/2015/02/150226122437.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.neuroimage.2015.10.039,Computer_Science_411,"""Seeing that individuals with more atypical neural responses also had more severe ASD symptoms suggests that these neural characteristics underlie or contribute to the core symptoms of ASD,"" Just said.","The NT group in the current study also showed activation decreases in the thalamus and hippocampus, areas associated with learning and memory.","The researchers also found that adaptation and synchronization were directly related to the severity of the participants' ASD symptoms. ""Seeing that individuals with more atypical neural responses also had more severe ASD symptoms suggests that these neural characteristics underlie or contribute to the core symptoms of ASD,"" Just said. ""It is possible that reduced neural adaptability during learning in ASD may lead to the behavioral symptoms of the disorder.","Nearby clusters showed a similar pattern in the ASD group, suggesting some overlap in the pattern of increasing activation over time between groups. The NT group in the current study also showed activation decreases in the thalamus and hippocampus, areas associated with learning and memory. Activation decreases in this network of areas in the NT participants suggest that their neural processes involved in task performance (encoding category members) became more efficient over time, achieving the same performance (with faster reaction times) using decreasing neural resources.","[4.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uiRDcWEPO6M/
10.1016/j.neuroimage.2015.05.038,Computer_Science_414,"The results ""provide validation for empathy being a multi-component construct, suggesting that affective and cognitive empathy are differentially represented in brain morphometry as well as providing convergent evidence for empathy being represented by different neural and structural correlates,"" the study states.",This highlights a consistent neural substrate for each component of empathy.,"People with higher levels of cognitive empathy, meanwhile, had more grey matter in the midcingulate cortex. The results ""provide validation for empathy being a multi-component construct, suggesting that affective and cognitive empathy are differentially represented in brain morphometry as well as providing convergent evidence for empathy being represented by different neural and structural correlates,"" the study states. This may provide some insight as to why rich people are historically averse to providing benefits to the poor.","showed that the affective component of empathy was more associated with insula activity, whereas the cognitive component of empathy was more associated with the midcingulate cortex and adjacent dorsomedial prefrontal cortex (MCC/dmPFC). This highlights a consistent neural substrate for each component of empathy. Considering our aims, peak MNI coordinates for affective (i.e., insula) and cognitive .","[5.0, 5.0, 2.0, 3.0, 5.0]",Computer_Science,train,5.0,news,http://www.medicaldaily.com/your-brain-structure-may-decide-how-you-empathize-emotional-brains-are-physically-339996
10.1038/s41586-019-1274-4,Computer_Science_415,"""In fact, through Foldit design, players have even discovered flaws in the Rosetta energy function -- our state-of-the-art method for protein design.""","First, a scientific model that holds within the domain space considered by practicing scientists may not hold outside of this domain.","""I never would have believed they would get that good, but Foldit players never cease to amaze us."" ""In fact, through Foldit design, players have even discovered flaws in the Rosetta energy function -- our state-of-the-art method for protein design."" ""Foldit players are a new addition to the research arsenal,"" said Khatib.","From these results, we can draw several general conclusions about scientific models, citizen science and the interplay between the two. First, a scientific model that holds within the domain space considered by practicing scientists may not hold outside of this domain. This is most vividly illustrated by the highly extended structures generated by Foldit players in their first de novo design efforts, and later by the structures with strained local geometry not previously sampled by Rosetta users.","[1.0, 4.0, 2.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39395949303&p=1pl&v=1&x=wRD0eV_wZnaQiNRsUMax8A
10.1098/rspb.2018.0727,Computer_Science_416,"The findings, which appear in Proceedings of the Royal Society B, could help paleontologists infer the range of motion of joints in a way that takes into account the soft tissues--particularly ligaments--that play key roles in how joints work.",(c) Implications of quail ROM mapping for reconstructing ornithodiran hip mobility Several extinct ornithodirans have been reconstructed with a 'batlike' hip pose in which the hip joints are severely abducted to include the hindlimbs in an aerofoil.,"""We think future studies should take into account that this pose was likely impossible, which might change our perspective when we consider the evolution of flight in pterosaurs and dinosaurs."" The findings, which appear in Proceedings of the Royal Society B, could help paleontologists infer the range of motion of joints in a way that takes into account the soft tissues--particularly ligaments--that play key roles in how joints work. But if I handed you a chicken skeleton without the ligaments, you might think that its joints could do all kinds of crazy things.","An application of this approach, using the data acquired in this study, follows below. (c) Implications of quail ROM mapping for reconstructing ornithodiran hip mobility Several extinct ornithodirans have been reconstructed with a 'batlike' hip pose in which the hip joints are severely abducted to include the hindlimbs in an aerofoil. In other words, although bony morphology alone permitted a batlike hip pose in the quail, the ligaments of the hip joint limited abduction enough to prevent it.","[3.0, 4.0, 3.0, 4.0, 1.0]",Computer_Science,train,3.0,news,https://www.futurity.org/pterodactyls-dinosaurs-flight-1766232-2/
10.1287/orsc.2013.0878,Computer_Science_417,"The study suggests that men benefit creatively from going head-to-head with other groups, while groups of women operate better in less competitive situations.","When groups are forced to go head-to-head with each other, we expect those composed of men to exhibit higher levels of creativity relative to groups composed of women.","Force teams to go head to head and the benefits of a female approach evaporate. The study suggests that men benefit creatively from going head-to-head with other groups, while groups of women operate better in less competitive situations. As intergroup competition heats up, men become more creative and women less so.","When operating in a competitive environment, however, this pattern is likely to change. When groups are forced to go head-to-head with each other, we expect those composed of men to exhibit higher levels of creativity relative to groups composed of women. Our explanation for this pattern again relies primarily on social role theory.","[5.0, 4.0, 5.0, 4.0]",Computer_Science,train,4.5,news,http://www.sciencedaily.com/releases/2014/08/140811165958.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1287/mnsc.2014.1985,Computer_Science_419,"The motivational impact of social incentives, coupled with sufficient tax breaks or additional advantages coming from customers, regulators, or investors, would make them as effective for employers as offering financial incentives.""","A sufficient degree of tax incentives, or sufficient additional advantages coming from customers, regulators, or investors, would make social incentives comparable to financial incentives.","""Our results indicate that social incentives may be slightly less effective than financial incentives in motivating workers, but the difference is not as large as one might have expected. The motivational impact of social incentives, coupled with sufficient tax breaks or additional advantages coming from customers, regulators, or investors, would make them as effective for employers as offering financial incentives."" When participants could choose how much of their performance related pay they would like to share with a charity, and how much they wanted to keep for themselves, performance increased considerably.","The first one is that several studies have documented how non-students are generally more prosocially inclined than students (see for instance Falk Our results indicate that social incentives may be less effective than financial incentives in motivating workers, but the difference is not as large as one might have expected. A sufficient degree of tax incentives, or sufficient additional advantages coming from customers, regulators, or investors, would make social incentives comparable to financial incentives. Also, one could expect social incentives to become increasingly more effective in motivating employees relative to financial incentives as earnings increase and the marginal utility of money decreases.","[4.0, 5.0, 5.0, 5.0]",Computer_Science,train,4.75,news,http://www.sciencedaily.com/releases/2015/01/150106203000.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1177/1080569913501862,Computer_Science_42,Higher-income professionals had less tolerance for smartphone use in business meetings.,"Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Women showed far less acceptance for the use of mobile phones during informal meetings. Also, professionals from the Southwest were less likely to be accepting of mobile phone use during informal meetings. Based on the findings, we have made several basic conclusions.","[2.0, 4.0, 1.0, 3.0, 3.0]",Computer_Science,train,2.6,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/2472555218773086,Computer_Science_420,"However, in the context of high-throughput screening, flow cytometry is slow, low-throughput, and is not amenable to automation.",Each of these examples demonstrates the power of flow cytometry when applied in an automated and high-throughput manner.,"However, in the context of high-throughput screening, flow cytometry is slow, low-throughput, and is not amenable to automation. The system can achieve a throughput of 50,000 wells per day, resulting in a fully automated platform that enables robust phenotypic drug discovery. This is dependent upon the ability to establish complex, biologically relevant screening assays and run high-throughput screening campaigns.","The ability to miniaturize the assay to 1536-well format, but still use flow cytometry as a readout, enabled us to screen more compounds while retaining a disease-relevant phenotypic screen. Each of these examples demonstrates the power of flow cytometry when applied in an automated and high-throughput manner. Phenotypic screening allows one to establish a screening assay without a full understanding of all possible molecular mechanisms of action that drive the disease pathology.","[3.0, 3.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=34178124819&p=1pl&v=1&x=TZzM9isXxcgRCwlbUw1Q1A
10.1016/j.neuroimage.2013.10.028,Computer_Science_422,"""These results showed that participants were successfully using neurofeedback to alter their pattern of brain activity according to a predefined objective in specific regions of their brain's motor cortex, without moving any body part.",We found that the modulation of these predefined components of brain dynamics was reinforced by real-time visual feedback to subjects and is specific of targeted brain regions.,"""The remarkable thing is that with each training session, the participants were able to reach the target aim faster, even though we were raising the bar for the target objective in each session, the way you raise the bar each time in a high jump competition,"" the researchers said. ""These results showed that participants were successfully using neurofeedback to alter their pattern of brain activity according to a predefined objective in specific regions of their brain's motor cortex, without moving any body part. This demonstrates that MEG source imaging can provide brain region-specific real time neurofeedback and that longitudinal neurofeedback training is possible with this technique.""","The targeting of pre-selected brain regions and the training of specific fast components of time-resolved brain activity within these regions is possible with real-time MEG-imaging neurofeedback. We found that the modulation of these predefined components of brain dynamics was reinforced by real-time visual feedback to subjects and is specific of targeted brain regions. Overall, this study opens new perspectives in the development of new therapeutic strategies based on real-time neurofeedback training, with direct access to the broadest range of neural dynamics, known to be affected by most neurological and neuropsychiatric conditions .","[4.0, 4.0, 4.0, 5.0]",Computer_Science,train,4.25,news,http://www.redorbit.com/news/health/1113051235/retraining-the-brain-with-neurofeedback-012114/
10.1038/s41598-017-17553-1,Computer_Science_424,"Despite this, bees can be tricked into taking tempting shortcuts between flowers even at the cost of increasing the overall distance they have to fly.","Crystallisation of early legs of the route and a preference for short between-feeder travel distances both have the effect of greatly reducing the vast number of potential route options available and may, under many circumstances, allow bees to alight on a close-to-optimal route in a short space of time.","Despite this, bees can be tricked into taking tempting shortcuts between flowers even at the cost of increasing the overall distance they have to fly. The result was one of the largest and most complete datasets on bee flight ever recorded and provided an in-depth look at route development for the first time ever. They found that focussing simply on sequences of visits to feeder stations, rather than the actual movements between stations or the way that routes develop, is insufficient to understand how animals solve route optimisation problems.","Our study supports the idea that there are some spatial arrangements of foraging resources for which bumblebee foragers are unable to develop a stable, efficient trapline route. Crystallisation of early legs of the route and a preference for short between-feeder travel distances both have the effect of greatly reducing the vast number of potential route options available and may, under many circumstances, allow bees to alight on a close-to-optimal route in a short space of time. These same heuristics can, however, lead to suboptimal routes under certain conditions such as the array we designed for this experiment.","[5.0, 2.0, 3.0, 3.0, 5.0]",Computer_Science,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/bz9ldxy9nno/
10.1287/mksc.2014.0864,Computer_Science_425,"The largest synergy between product placement and advertising occurs when the placement and ad feature the same brand but different categories, giving rise to a 10.8% reduction in audience loss.","Also, interestingly, in contrast to a negative impact of a brand's prior advertising on its audience size found in the literature , we find that a brand's placements can contribute to an increased commercial audience size.","In particular, when the same product is featured in the placement and the ad, the audience loss during the ad decreases by 5%. The largest synergy between product placement and advertising occurs when the placement and ad feature the same brand but different categories, giving rise to a 10.8% reduction in audience loss. According to author Tanner, ""the synergistic effects that we observe reveal that the strategic use of product placement can contribute to increased audience sizes during a brand's subsequent commercials.""","These findings are also highly relevant to research on ad avoidance, as they reveal a specific way in which the actual program (rather than advertising) content can materially influence the extent to which downstream advertisements are avoided. Also, interestingly, in contrast to a negative impact of a brand's prior advertising on its audience size found in the literature , we find that a brand's placements can contribute to an increased commercial audience size. Hence, our results suggest that there may be synergistic advantages in using the media budget to combine placements and advertising rather than relying on advertising alone.","[3.0, 2.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.6,news,http://www.sciencedaily.com/releases/2014/10/141015131920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/scirobotics.aat5999,Computer_Science_426,"I can also see the robot serve as the facilitator within a group of kids to help guide their conversation, and act as a peer resource for the group.a

But Mutlu cautioned that aWe have be careful in identifying and designing for these opportunities, as we do not want robots to replace natural ways of learning or available resources, such as interaction with a parent or an educator.a He also tells Inverse, ain principle, a robot like Minnie can be used by adult learners as well, although its behaviors and support for reading must be designed specifically for the target user group.a

It should be noted that athere was a measurable reduction in time spent reading over timea in the study, and the authors suggested that some technical aspects of the robot that the kids found afrustratinga may have kept the children from reading more often as time went on.","In summary, our social robot, Minnie, demonstrates the potential for transforming reading at home from an isolated activity into a social and collaborative experience that can promote comprehension and interest in reading.","Michaelis tells Inverse, aI can see our approach being applied in or out of a classroom whenever someone would benefit from learning with a social partner, but a human partner isnat available. I can also see the robot serve as the facilitator within a group of kids to help guide their conversation, and act as a peer resource for the group.a

But Mutlu cautioned that aWe have be careful in identifying and designing for these opportunities, as we do not want robots to replace natural ways of learning or available resources, such as interaction with a parent or an educator.a He also tells Inverse, ain principle, a robot like Minnie can be used by adult learners as well, although its behaviors and support for reading must be designed specifically for the target user group.a

It should be noted that athere was a measurable reduction in time spent reading over timea in the study, and the authors suggested that some technical aspects of the robot that the kids found afrustratinga may have kept the children from reading more often as time went on. The researchers observed in a paper last year that a wider breadth of study is needed on Minnie a longer amounts of time, different settings, different ages of children, and so ona but are encouraged by their work .","Although these deliberate technical simplifications produced a fairly robust system, enabling extended maintenance-free use in the field, improving the core technology and the interactivity of the social robot platform will offer a more seamless user experience. In summary, our social robot, Minnie, demonstrates the potential for transforming reading at home from an isolated activity into a social and collaborative experience that can promote comprehension and interest in reading. Our results illuminate how we might maximize the societal benefits of imminent robotic technology and demonstrate how the integration of social robots into an existing human activity can transform human experience toward this good.","[3.0, 5.0, 3.0, 5.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34885653902&p=1pl&v=1&x=5Wz_Ja9gwhTCgAoLd6rofw
10.1126/science.aar3106,Computer_Science_428,"In this paper, the researchers prove that a quantum computer with a fixed circuit depth is able to outperform a classical computer that's tackling the same problem because the classical computer will require the circuit depth to grow larger, while it can stay constant for the quantum computer.",We prove that constant-depth quantum circuits are more powerful than their classical counterparts.,"Because they have such short coherence time before the system becomes chaotic and useless for any computations, you can only perform a relatively small number of operations on them. In this paper, the researchers prove that a quantum computer with a fixed circuit depth is able to outperform a classical computer that's tackling the same problem because the classical computer will require the circuit depth to grow larger, while it can stay constant for the quantum computer. There is very little that's intuitive about quantum computing, of course, but it's worth remembering that quantum computers are very different from classical computers.","We prove that constant-depth quantum circuits are more powerful than their classical counterparts. We prove that any classical probabilistic circuit composed of bounded fan-in gates that solves the 2D Hidden Linear Function problem with high probability must have depth logarithmic in n. In contrast, we show that this problem can be solved with certainty by a constant-depth quantum circuit composed of one-and two-qubit gates acting locally on a two-dimensional grid. Many problems of practical importance such as Monte Carlo simulation, computing the rank, the determinant, and the inverse of a matrix lend themselves naturally to parallelization .","[5.0, 4.0, 5.0, 5.0]",Computer_Science,train,4.75,news,http://ct.moreover.com/?a=37430575051&p=1pl&v=1&x=T5Q42fQBOeGHhNHbJz5n6A
10.1126/scirobotics.aat7111,Computer_Science_429,"This can be especially helpful when robots step in caretaker-like roles, like when they act as museum tour guides, elderly care aids, or childhood education assistants.",projected the lines of length up to 110 cm onto a projection area and found that adult participants were influenced by their peers but not by the robots (with neither ambiguous nor unambiguous stimuli).,"According to the paper, this reinforces the idea of humans treating computers and robots as social beings, ""attributing human-like qualities to technology."" This can be especially helpful when robots step in caretaker-like roles, like when they act as museum tour guides, elderly care aids, or childhood education assistants. But as the researchers warn, ""although conforming can be beneficial, the potential for misuse and the potential impact of erroneous performance cannot be ignored.""","It appears that adults in our study did not conform to the group of robots, confirming recent studies . projected the lines of length up to 110 cm onto a projection area and found that adult participants were influenced by their peers but not by the robots (with neither ambiguous nor unambiguous stimuli). Children in our study, on the other hand, seemed to conform to the robots.","[2.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34850376759&p=1pl&v=1&x=B0aXIptuqedVgJ90L6an1g
10.1111/cogs.12138,Computer_Science_431,"After hearing these stories, the secular children were more likely to see the character as make-believe, while the religious children were more likely to see the character as real.",These results are consistent with the earlier findings of .,"Unexpectedly, though, a real difference appeared when the children were told fantasy stories, in which the lead character performed some supernatural or magical event. After hearing these stories, the secular children were more likely to see the character as make-believe, while the religious children were more likely to see the character as real. Considering the results of their experiments, the researchers theorize exposure to religion might encourage children to entertain ideas of special or superhuman power and thus ""even if children have no natural inclination to believe in divine or superhuman agency, religious instruction can readily lead them to do so.""","For example, children who claimed to have heard of George Washington and Snow White correctly categorized the former as a real person and the latter as a fictional character. These results are consistent with the earlier findings of . Children's systematic categorization of these familiar characters shows that they understood the instructions and the difference between the two categories.","[3.0, 4.0, 2.0, 1.0, 1.0]",Computer_Science,train,2.2,news,http://www.medicaldaily.com/fantasy-or-reality-children-religious-backgrounds-less-able-detect-fictional-characters-295684
10.1038/nn.4354,Computer_Science_432,"However, the region that would become the VWFA was already different from adjacent cortex in its connectivity patterns.","Furthermore, the ability to predict later brain function from an anatomical scan that can be performed even in a sleeping infant Figure 5 Left-lateralized regions that are preferentially connected with the VWFA versus lFFA or lPFS at age 5.","The researchers saw no indication from fMRI scans that the VWFA was responding to words at age 5. However, the region that would become the VWFA was already different from adjacent cortex in its connectivity patterns. These patterns were so distinctive that they could be used to accurately predict the precise location where each child's VWFA would later develop.","In sum, our longitudinal, cross-lagged study supports the hypothesis that early connectivity instructs the functional development of the VWFA, a cortical region that underlies the uniquely human ability to read. Furthermore, the ability to predict later brain function from an anatomical scan that can be performed even in a sleeping infant Figure 5 Left-lateralized regions that are preferentially connected with the VWFA versus lFFA or lPFS at age 5. Connectivity (of the region that will become the VWFA) to these regions was already elevated (compared to nearby cortex) at age 5, even when no evidence of functional differentiation existed in the VWFA at that age.","[4.0, 2.0, 2.0, 4.0, 2.0]",Computer_Science,train,2.8,news,http://news.mit.edu/2016/brain-connections-key-reading-0808
10.1038/s41598-019-40888-w,Computer_Science_433,These high-resolution 3D images provided detailed information about a tumor's volume and the structure of its blood vessel networks.,Figure 6b illustrates how one can visualize this heterogeneous hemodynamic landscape in Tumor 1 by www.nature.com/scientificreports www.nature.com/scientificreports/ mapping each vessel class onto the underlying microvascular network.,"""Poor representations of the tumor 'microenvironment' make models and the research based on them less accurate. These high-resolution 3D images provided detailed information about a tumor's volume and the structure of its blood vessel networks. ""It looked an awful lot like Google Maps,"" says Pathak, ""The blood vessel segments are the streets and the blood flow in each segment is analogous to the traffic along each street.""","Collectively, Class 3 vessels lack the full functionality of Class 2 vessels, yet are capable of maintaining transport better than Class 1 vessels. Figure 6b illustrates how one can visualize this heterogeneous hemodynamic landscape in Tumor 1 by www.nature.com/scientificreports www.nature.com/scientificreports/ mapping each vessel class onto the underlying microvascular network. Almost 90% of the vascular volume in this tumor was accounted for by Class 1 vessels that were poorly or minimally perfused, hypoxic and also exhibited the smallest median diameter among all vascular classes (Fig.","[4.0, 3.0, 4.0, 5.0, 1.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=39158381133&p=1pl&v=1&x=xsThtZOEgth7s-laeZWh9Q
10.1126/sciadv.aat7422,Computer_Science_434,"""The fact that stability of core language skill across so long a period began so early, was sustained so long, transcended several heterogeneous moderating factors, and was maintained over and above covariates points to a highly conserved and robust individual-differences characteristic in human beings,"" the authors write.","With respect to the four challenges posed at the outset, clear evidence emerged for individual variation in a core language skill at each of 11 ages, for convergence of multiple indices of language at each age on latent variables representing a core language skill, for the homotypic and heterotypic stability of core language skill over the long term, and for the robustness of long-term stability of core language skill in atypically developing children with several different types of health risk.","They noted these results indicate that addressing delayed language skills early in development is beneficial. ""The fact that stability of core language skill across so long a period began so early, was sustained so long, transcended several heterogeneous moderating factors, and was maintained over and above covariates points to a highly conserved and robust individual-differences characteristic in human beings,"" the authors write. ""It further suggests that the search for mechanism(s) underlying stability of core language skill in children is likely to reward basic science as well as applied clinical research.""","Individual differences tell us about the distribution of language skill, and their stability tells us about the nature and ontogeny of that language skill. With respect to the four challenges posed at the outset, clear evidence emerged for individual variation in a core language skill at each of 11 ages, for convergence of multiple indices of language at each age on latent variables representing a core language skill, for the homotypic and heterotypic stability of core language skill over the long term, and for the robustness of long-term stability of core language skill in atypically developing children with several different types of health risk. Thus, a consistent personological characteristic, experience, or environment can carry stability.","[4.0, 3.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.2,news,http://ct.moreover.com/?a=37874519433&p=1pl&v=1&x=lyvlZTgxXDm0B2racUnzkw
10.1287/mnsc.2014.2100,Computer_Science_435,"For instance, exposure to an entrepreneurial environment appears likely to increase an individual's willingness to work in a startup, but doesn't seem to boost their interest in being a founder.","Although we believe that individuals' perceptions of norms should be the most direct predictor of interests, a potential limitation is that individuals with a stronger pre-existing interest in entrepreneurship may perceive norms as being more entrepreneurial than they are.","[related]

The data may also help provide information on how context affects careers. For instance, exposure to an entrepreneurial environment appears likely to increase an individual's willingness to work in a startup, but doesn't seem to boost their interest in being a founder. ""An interest in being a founder is more closely associated with individual traits and preferences that predispose them to entrepreneurship,"" Roach says.","It should be noted that this measure reflects individuals' perceptions of norms rather than ""objective"" consensus-based norms. Although we believe that individuals' perceptions of norms should be the most direct predictor of interests, a potential limitation is that individuals with a stronger pre-existing interest in entrepreneurship may perceive norms as being more entrepreneurial than they are. The preference measures included in the regressions should account for some of this effect, and we further address this concern in the empirical analysis.","[3.0, 3.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.2,news,http://www.futurity.org/startups-joiners-founders-941672/
10.1038/s41586-018-0520-5,Computer_Science_436,"After training, the mice detected the non-associated tone better than the ""walking"" tone when they were actually walking, even though they detected both tones equally well when they were standing still.",The formation of this auditory cortical filter required a predictable and relatively prolonged association of movement with an ensuing sound.,"They were able to identify the inhibitory neurons that responded to the artificial tone to cancel out its signal, ""exactly like noise cancelling,"" Schneider says. After training, the mice detected the non-associated tone better than the ""walking"" tone when they were actually walking, even though they detected both tones equally well when they were standing still. For a mouse being stalked by a nearby cat, it would be a matter of survival.","3b-d ), indicating that circuits local to the auditory cortex are a likely source of the reafferent notch filter that arises following aVR experience. The formation of this auditory cortical filter required a predictable and relatively prolonged association of movement with an ensuing sound. Mice acclimated for about a week on a treadmill in which fixed-frequency tones were presented only at rest did not display enhanced cortical suppression at the training frequency during rest or running (Extended Data Fig.","[4.0, 2.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.8,news,https://www.futurity.org/hearing-footsteps-brains-1864632/
10.1145/3133956.3134002,Computer_Science_437,The space for combosquatting is almost infinite because attackers can register as many domains as they want with any variation that they want.,We see that the hosting infrastructure of malicious combosquatting domains is concentrated in certain autonomous systems and they are scattered across numerous different CIDRs-which is different from the behavior of combosquatting domains in general.,"""We found orders of magnitude more combosquatting domains than typosquatting domains, for instance. The space for combosquatting is almost infinite because attackers can register as many domains as they want with any variation that they want. In some cases, registering a domain can cost less than a dollar.""","We should note that Figure 6 shows aggregate statistics of 20,000 bins in the x-axis. We see that the hosting infrastructure of malicious combosquatting domains is concentrated in certain autonomous systems and they are scattered across numerous different CIDRs-which is different from the behavior of combosquatting domains in general. As expected, generic combosquatting activity is spread across the globe with no obvious concentrations.","[4.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/qLy8STSplI4/
10.1073/pnas.1606075113,Computer_Science_438,"""As turbulent levels rise, the glider can avoid losing height by adopting increasingly conservative, risk-averse flight strategies, such as continuing along the same path rather than turning.""","For the learned policies in the regimes of moderate and strong turbulence levels, the glider adopts an increasingly conservative policy as turbulence levels increase, quantifying the degree of risk affordable in turbulent environments.","""By sensing two environmental cues-vertical wind acceleration and torque-the glider is able to climb and stay within the thermal core, where the lift is typically the largest, resulting in improved soaring performance, even in the presence of strong turbulent fluctuations,"" said Vergassola. ""As turbulent levels rise, the glider can avoid losing height by adopting increasingly conservative, risk-averse flight strategies, such as continuing along the same path rather than turning."" The researchers write in their paper that, based on their study, ""torque and vertical accelerations"" appear to be the sensorimotor cues that most effectively guide the most efficient soaring path of birds through thermals, rather than differences in temperature.","Furthermore, the problem is technologically relevant to extend the flying range of autonomous gliders. For the learned policies in the regimes of moderate and strong turbulence levels, the glider adopts an increasingly conservative policy as turbulence levels increase, quantifying the degree of risk affordable in turbulent environments. Reinforcement learning uncovers those sensorimotor cues that permit effective control over soaring in turbulent environments.","[5.0, 3.0, 2.0, 5.0]",Computer_Science,train,5.0,news,http://healthmedicinet.com/news/scientists-determine-how-birds-soar-to-great-heights/
10.1098/rsos.150266,Computer_Science_439,And they found that papers with terser titles top the citation count.,Our analysis suggests that papers with shorter titles do receive greater numbers of citations.,"[Adrian Letchford, Helen Susannah Moat, Tobias Preis, The advantage of short paper titles]

Scientific careers can be made or waylaid on the basis of publications. And they found that papers with terser titles top the citation count. Even when the researchers took into account the journal in which the publication appeared--some have stricter restrictions on title length than do others--the findings held true.","length of a paper's title bears no relation to its scientific impact , or that longer titles can be linked to greater citation counts . Our analysis suggests that papers with shorter titles do receive greater numbers of citations. When citation counts are adjusted for the journal in which the paper is published, we find that the strength of the evidence for the relationship between title length and citations received is reduced.","[5.0, 4.0, 5.0, 5.0, 5.0]",Computer_Science,train,4.8,news,http://www.scientificamerican.com/podcast/episode/terse-titles-cited/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+basic-science+%28Topic%3A+More+Science%29
10.1098/rsif.2014.0826,Computer_Science_440,"Data smashing principles may open the door to understanding increasingly complex observations, especially when experts do not know what to look for, according to the researchers.","Our key observation, presented here, is that all quantitative data streams have corresponding anti-streams, which in spite of being non-unique, are tied to the stream's unique statistical structure.","The more information remained, the less likely the streams originated in the same source. Data smashing principles may open the door to understanding increasingly complex observations, especially when experts do not know what to look for, according to the researchers. The authors demonstrated the application of their principle to data from real-world problems, including the disambiguation of electroencephalograph patterns from epileptic seizure patients; detection of anomalous cardiac activity from heart recordings; and classification of astronomical objects from raw photometry.","We suggest that this process, which we call data smashing, may open the door to understanding increasingly complex data in the future, especially when experts cannot keep pace. Our key observation, presented here, is that all quantitative data streams have corresponding anti-streams, which in spite of being non-unique, are tied to the stream's unique statistical structure. The results show that without access to any domain knowledge, the unmodified data smashing process performs on a par with specialized algorithms devised by domain experts for each problem independently.","[3.0, 1.0, 5.0, 2.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141009125646.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/nature13404,Computer_Science_442,"The scientists added in their report, ""The precise control over interface geometry offered by our method enables the design of two-component protein nanomaterials with diverse nanoscale features, such as surfaces, pores, and internal volumes, with high accuracy.""","In the structures with resolutions that permit detailed analysis of side-chain configurations (T33-15 and two independent crystal forms of T33-21), 87 of 113 side chains at the designed interfaces adopt the predicted conformations (Supplementary Tables 5 and  6 ).","Further down the road, he and Bale anticipate that these design methods might also be useful for developing new clean energy technologies. The scientists added in their report, ""The precise control over interface geometry offered by our method enables the design of two-component protein nanomaterials with diverse nanoscale features, such as surfaces, pores, and internal volumes, with high accuracy."" They went on to say that the combinations possible with two-component materials greatly expand the number and variety of potential nanomaterials that could be designed.","In all cases, the structures reveal that the inter-building-block interfaces were designed with high accuracy: comparing a pair of chains from each structure to the computationally designed model yields backbone root mean square Table 1 ). In the structures with resolutions that permit detailed analysis of side-chain configurations (T33-15 and two independent crystal forms of T33-21), 87 of 113 side chains at the designed interfaces adopt the predicted conformations (Supplementary Tables 5 and  6 ). over all 24 subunits in each material range from 1.0 to 2.6 Å (Fig.","[2.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.5,news,http://www.sciencedaily.com/releases/2014/06/140605093315.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/nature12112,Computer_Science_443,The activity of the hippocampal place cells - specialized brain cells involved in navigation - suggested that during the rest the animals simulated walking to and from food that they had been unable to reach.,"Thus, animals were required to learn a new goal location, demanding a flexible behavioural response that was more likely to engage the hippocampus than a fixed reference-memory response 31 .","The activity of the hippocampal place cells - specialized brain cells involved in navigation - suggested that during the rest the animals simulated walking to and from food that they had been unable to reach. ""During sleep or rest, the hippocampus replays journeys through this map which may help strengthen the memory. Whether or not rats experience this brain activity as dreams is still unclear, as we would need to ask them to be sure.""","First, because the shortest routes in phase one and two were matched, it was determined that animals could remember Home, but could not detect Random locations, because latencies and path lengths were significantly shorter for Home-bound trajectories ( Fig. Thus, animals were required to learn a new goal location, demanding a flexible behavioural response that was more likely to engage the hippocampus than a fixed reference-memory response 31 . Hence during this period, every Home-bound trajectory was always a novel combination of current location and goal location.","[3.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.25,news,http://www.sci-news.com/othersciences/neuroscience/science-rats-dream-about-future-02961.html
10.1016/j.ijmedinf.2013.11.003,Computer_Science_444,"""By understanding the dynamic nature of eye-gaze patterns and how technology impacts these patterns, we can contribute to future EHR designs that foster more effective doctor-patient interaction.""","The study described in this paper focuses on gaze, but similar approaches can be used to understand the effects of other interactions that contribute to patient outcomes such as emotion.","Understanding physicians' eye-gaze patterns and their effects on patients can contribute to more effective training guidelines and better-designed technology. Future systems, for example, could include more interactive screen sharing between physicians and patients, Montague said. ""By understanding the dynamic nature of eye-gaze patterns and how technology impacts these patterns, we can contribute to future EHR designs that foster more effective doctor-patient interaction.""","In these cases, to understand emotion, you would want to understand when the emotional state changes and the events that trigger the change, the events that influence the emotion are also the points that can lead to redesign or training. The study described in this paper focuses on gaze, but similar approaches can be used to understand the effects of other interactions that contribute to patient outcomes such as emotion. The results showed that doctor's gaze patterns are followed significantly by patient gaze patterns, for instance if doctor gazed at the patient, the patient gazed back at the doctor.","[5.0, 3.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.6,news,http://www.sciencedaily.com/releases/2014/01/140124115750.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspa.2014.0182,Computer_Science_445,It is crucial to give an account as to how the abstract represents the physical.,"The two directions of the representation relation, modelling from physical to abstract, and instantiation from abstract to physical, lie at the heart of our questions around when a physical system computes.",For this reason it is not sufficient to say that a physical-abstract system pair is enough for computation. It is crucial to give an account as to how the abstract represents the physical. Models are not isolated: they emerge from within certain theories.,"While these two directions of representation are not absolutely disjoint, the exasperation sometimes expressed by experimentalists towards the unrealistic demands of theorists has its roots in the asymmetries of the representation relation between physical and abstract entities. The two directions of the representation relation, modelling from physical to abstract, and instantiation from abstract to physical, lie at the heart of our questions around when a physical system computes. This is an important point: the representation relation is theory-dependent.","[3.0, 4.0, 5.0, 3.0, 2.0]",Computer_Science,train,3.4,news,http://www.technology.org/2014/05/08/scientists-provide-new-universal-definition-computing/
10.1145/2493432.2493486,Computer_Science_446,"Once printed, the circuits can be attached to electronic components using conductive double-sided tape or silver epoxy adhesive, allowing full-scale prototyping in mere hours.","Using instant inkjet circuits in the classroom it would be possible to introduce students to basic electronics principles very cheaply, and coupled with the use of anisotropic self-adhesive tape a range of electronic components could be used to augment the experience.","""The method can be used to print circuit boards, sensors and antennas with little cost, and it opens up many new opportunities."" Once printed, the circuits can be attached to electronic components using conductive double-sided tape or silver epoxy adhesive, allowing full-scale prototyping in mere hours. The homemade circuits might allow tinkerers to quickly prototype crude calculators, thermostat controls, battery chargers or any number of electronic devices.","Not only could cheap sensors like this be useful in a UbiComp setting, but they could also be valuable for education. Using instant inkjet circuits in the classroom it would be possible to introduce students to basic electronics principles very cheaply, and coupled with the use of anisotropic self-adhesive tape a range of electronic components could be used to augment the experience. Ultimately it might be possible to adopt a solderless modular electronics platform like .NET Gadgeteer to use an inkjet printed substrate for interconnect instead of individual cables.","[4.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.25,news,http://www.sciencedaily.com/releases/2013/11/131106122031.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1529100615569721,Computer_Science_447,"The researchers point out that many apps feature content that seems educational, like letters or numbers, but this doesn't mean that they have true educational value.",We must find ways to help parents assess apps that exist in this first wave .,"While not all of these principles are necessary, the more an app promotes these types of learning experiences, the greater the educational value of the app will likely be. The researchers point out that many apps feature content that seems educational, like letters or numbers, but this doesn't mean that they have true educational value. These findings suggest that apps that feature attention-grabbing sound, movement, or other visual elements may be more distracting than they are engaging, and are unlikely to serve as effective educational tools.","While this may sound encouraging to app developers and users, little detail was offered about the study design, making it difficult to evaluate its scientific impact. We must find ways to help parents assess apps that exist in this first wave . While there is no way to scientifically study every app on the market, a set of principles based on science can be developed and used to evaluate the current crop of apps.","[4.0, 2.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.2,news,http://www.healthcanal.com/mental-health-behavior/62608-science-of-learning-can-help-parents-developers-grade-educational-apps.html
10.1509/jmr.14.0591,Computer_Science_448,"Further, both the anticipation of the leisure activity and enjoyment from it decreased once it was scheduled.",We suggest that both sources of utility can be diminished for scheduled leisure.,"Further, both the anticipation of the leisure activity and enjoyment from it decreased once it was scheduled. ""To my surprise, however, I soon started to feel reluctant and unenthusiastic at the prospect of the long-awaited reunions that I had scheduled. I began to think of each scheduled activity as more like an obligation, even a chore, rather than an enjoyable outing.","However, unlike the prior research demonstrating how work versus leisure goals alter the experience of an ambiguous activity, we argue that a subtle manipulation (i.e., scheduling) of an unambiguous leisure activity can make the activity feel more like work and decrease utility. We suggest that both sources of utility can be diminished for scheduled leisure. Together, our results provide support for the detrimental effect of scheduling on how leisure activities are anticipated and experienced.","[3.0, 2.0, 5.0, 4.0]",Computer_Science,train,3.5,news,http://www.futurity.org/free-time-schedules-1119662-2/
10.1002/admt.201700235,Computer_Science_450,"We hope this will save lives by reducing medical errors during surgery,"" McAlpine added.","The 3D printed prostate model demonstrated high fidelity with patient organ and tissue in ana tomical, static and dynamic mechanical, hardness, and optical properties.","""We think these organ models could be 'game-changers' for helping surgeons better plan and practice for surgery. We hope this will save lives by reducing medical errors during surgery,"" McAlpine added. This limits their application for accurate prediction and replication of the organ's physical behavior during surgery.","In summary, we have designed and developed a series of novel methodologies and customized inks for fabricating a 3D printed prostate model with physical properties of tissue and integrated sensing capabilities that can be used for quantitative, advanced surgical rehearsal. The 3D printed prostate model demonstrated high fidelity with patient organ and tissue in ana tomical, static and dynamic mechanical, hardness, and optical properties. Therefore, the prostate model can aid medical pro fessionals to perform more effective preoperative planning and rehearsal and predict organ physical behavior more accurately.","[3.0, 2.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.2,news,https://www.sciencedaily.com/releases/2017/12/171206122609.htm
10.1287/mksc.2013.0837,Computer_Science_451,Their results show that different faces affect ad effectiveness substantially and people show substantial differences in their facial preferences across product categories.,Ad agencies should also pay attention to possible heterogeneity in the preferences of the target audience and use different faces to target different customer segments.,"""This technique will revolutionize the field of ad design,"" predicts author Min Ding. Their results show that different faces affect ad effectiveness substantially and people show substantial differences in their facial preferences across product categories. ""An 8% increase in effectiveness could produce a substantial gain for the $600 billion ad industry,"" says author Li Xiao.","The substantial effect of different faces on advertising effectiveness indicates that ad agencies should be careful when selecting faces to appear in print advertisements. Ad agencies should also pay attention to possible heterogeneity in the preferences of the target audience and use different faces to target different customer segments. In addition, the methods used in the present study provide a new approach for professionals interested in conducting a quantitative study to assist in the screening and selection of print media spokespersons.","[3.0, 4.0, 5.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://www.sciencedaily.com/releases/2014/04/140411103140.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-019-08746-5,Computer_Science_452,"Most networks don't look scale-free at all.""","Hence social networks are at best only weakly scale free, with 70% and 55% exhibiting the weakest or weak direct evidence of scale-free structure, respectively.","What we've found now is that there is little evidence for classically scale-free networks except in a few specific places. Most networks don't look scale-free at all."" Many types of networks look similar from a distance.","And second, among the categories representing direct evidence of scale-free structure, not a single network data set falls into the Strong or Strongest categories. Hence social networks are at best only weakly scale free, with 70% and 55% exhibiting the weakest or weak direct evidence of scale-free structure, respectively. The social networks exhibiting weak evidence include about a third of the Facebook online social networks and half of the board of director networks.","[4.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=38690852896&p=1pl&v=1&x=By14RRHF__sXAOUUs0uMsQ
10.1126/sciadv.aap9815,Computer_Science_453,"""There are some people who have highly desirable traits and are going to be more in demand, so they're going to be able to be choosier about who they mate with.","The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones.","More importantly, though, once you exit the parameters of desirability set by a dating site, it becomes less clear whether you can say that any of us really has a so-called ""mate value."" ""There are some people who have highly desirable traits and are going to be more in demand, so they're going to be able to be choosier about who they mate with. And then there are people who are going to be lower in demand and generally higher in supply, and those people are going to be buyers in the market.""","The lower set of curves in the top panels shows the probability of receiving a reply to an initial message. The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones. The differences are stark: men are more than twice as likely to receive a reply from women less desirable than themselves than from more desirable ones, and for messages sent to more desirable women the reply rate never rises above 21%.","[1.0, 4.0, 3.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34956735733&p=1pl&v=1&x=Xyl0ZsFrf-4Ho4UgaTPtHQ
10.1073/pnas.1800708115,Computer_Science_455,"This slow-down effect before nouns may also help explain why complex forms, such as prefixes, are more common in verbs, the study suggested.",These conditions on noun use appear to outweigh potential advantages stemming from differences in internal complexity between nouns and verbs.,"On second reference, most speakers use pronouns instead. This slow-down effect before nouns may also help explain why complex forms, such as prefixes, are more common in verbs, the study suggested. The findings advance knowledge of how the human brain processes language, researchers said.","We attribute this slowdown effect to the increased amount of planning that nouns require compared with verbs. These conditions on noun use appear to outweigh potential advantages stemming from differences in internal complexity between nouns and verbs. Our findings suggest that, beneath the staggering diversity of grammatical structures and cultural settings, there are robust universals of language processing that are intimately tied to how speakers manage referential information when they communicate with one another.","[4.0, 2.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34163792137&p=1pl&v=1&x=y2uAVjWmZKYeZZApLsYm0A
10.1016/j.eswa.2014.03.024,Computer_Science_458,Criminal networks are just as social as friendship or business networks.,"Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well.","The study of social networks is providing dramatic insights into the nature of our society and how we are connected to one another. Criminal networks are just as social as friendship or business networks. So the same techniques that can tease apart the links between our friends and colleagues should also work for thieves, drug dealers, and organized crime in general.","It has to be repeated m times, so the worst computational cost is O(m 2 n), or O(n 3 ) for sparse graphs. Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well. The number of the edges to be deleted can be chosen interactively.","[2.0, 2.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.2,news,http://www.technologyreview.com/view/526471/how-to-detect-criminal-gangs-using-mobile-phone-data/
10.1038/s41562-018-0510-5,Computer_Science_459,"So predictable

But most users interact with a variety of people online, and it could be that some interactions are more relevant than others.",We found that the self-predictability of users was actually independent of activity frequency (SM) but there were strong associations between activity frequency and social information flow: egos who posted 8 times per day on average were ≈17% more predictable given their alters than egos who posted once per day on average (Fig.,"Put differently, a user's own history gave a predictability of 40-70 percent, while their friend's history provided a predictability of zero to 60 percent. So predictable

But most users interact with a variety of people online, and it could be that some interactions are more relevant than others. So, the authors continued to add interacting users and found that each improved the predictability (or, put differently, lowered the entropy).","Individuals who post frequently to social media, keeping up on current events, may provide more predictive information about either themselves or their social ties than other, infrequent posters. We found that the self-predictability of users was actually independent of activity frequency (SM) but there were strong associations between activity frequency and social information flow: egos who posted 8 times per day on average were ≈17% more predictable given their alters than egos who posted once per day on average (Fig. Interestingly, this trend reversed itself when considering the activity frequencies of the alters: alters who posted 8 times per day on average were ≈23% less predictive of their egos than alters who posted once per day on average.","[4.0, 4.0, 2.0, 2.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=38318877254&p=1pl&v=1&x=1vExZgUc137yeTF9t6DjiA
10.1016/j.neuroimage.2016.05.037,Computer_Science_460,"""We found that the quantitative reasoning component of intelligence correlated with brain volume, but not with the concentration of NAA in the brain,"" Paul said.","Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex).","""In our data, we observed two facets of fluid intelligence - one that involves quantitative or numeric reasoning, and another that involves verbal or spatial reasoning,"" Paul said. ""We found that the quantitative reasoning component of intelligence correlated with brain volume, but not with the concentration of NAA in the brain,"" Paul said. ""And the verbal and spatial components of intelligence correlated with NAA, but not with brain volume.""","The relationship of the PCC to regions involved in these final two stages, in concert with our results demonstrating PCC NAA to predict fluid reasoning ability, suggest that oxidative metabolism in the PCC may be reflective of high functioning in the frontal-parietal network responsible for hypothesis and response formation. Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex). The additional domains of cognition measured by our battery may provide clues about the relationship of NAA to Gf.","[4.0, 3.0, 2.0, 4.0, 2.0]",Computer_Science,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/nSCkr6Mh0aE/
10.1145/3290605.3300393,Computer_Science_461,"""Factors such as age should be considered when designing new smartphone authentication systems, and devices should allow users to pick the locking method that suits their needs and usage patterns,"" he said.","A consequence of this and the fact that people do regularly authenticate themselves while moving, means that newlydesigned unlocking mechanisms should be as robust in the presence of movement as existing mechanisms, in order to be acceptable for smartphone unlocking.","However, the balance shifts with age, with men in their 50s logging longer usage sessions than women of the same age. While the study didn't look at the reasons for these behaviours, Beznosov said the findings can help smartphone companies design better products. ""Factors such as age should be considered when designing new smartphone authentication systems, and devices should allow users to pick the locking method that suits their needs and usage patterns,"" he said.","This might indicate that current unlocking mechanisms are robust against errors on the move. A consequence of this and the fact that people do regularly authenticate themselves while moving, means that newlydesigned unlocking mechanisms should be as robust in the presence of movement as existing mechanisms, in order to be acceptable for smartphone unlocking. This requirement not only in uences how unlocking systems should be designed (e.g., constant eye contact might not be possible) but also how they are evaluated in studies (in-lab vs. in the wild).","[4.0, 3.0, 3.0, 2.0, 1.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=39504685122&p=1pl&v=1&x=FFEXDRIwbobH_WcqpXPkcQ
10.1073/pnas.1814646116,Computer_Science_462,"By the time they graduate with computer science degrees, however, the US students score significantly better, coming about 0.76 standard deviations ahead of their international peers.","The within-country gender gaps in CS skills, while significant, are generally smaller than the skill gaps between the United States and other countries as well as between elite and nonelite programs.","A comparison of undergraduate data indicates that US students enter college with lower math and physics scores as well as fewer physics classes than their counterparts overseas. By the time they graduate with computer science degrees, however, the US students score significantly better, coming about 0.76 standard deviations ahead of their international peers. There were no statistically significant difference among the students from other countries.","Males score 0.15 SDs higher than females in China (P = 0.093), 0.24 SDs higher in India (P = 0.077), 0.25 SDs higher in Russia (0.022), and 0.41 SDs higher in the United States (P = 0.000). The within-country gender gaps in CS skills, while significant, are generally smaller than the skill gaps between the United States and other countries as well as between elite and nonelite programs. Females in the United States score 0.35-0.42 SDs higher than males in China, India, or Russia (P = 0.000) and 0.52-0.67 SDs higher than females in China, India, or Russia (P = 0.000).","[4.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.25,news,http://ct.moreover.com/?a=38827204275&p=1pl&v=1&x=ELtmBzRLakPP5kgskUM19w
10.1073/pnas.1710231115,Computer_Science_463,"The benefits of forecasting

Beyond helping people plan their weekends, ecological forecasts will improve decision-making in agriculture, forestry, fisheries and other industries.","Ecological forecasting would benefit from cyberinfrastructure for the automation, public dissemination, and archiving of ecological forecasts, which will allow community advances in two important ways.","Developing this ability would be a win-win for both science and society. The benefits of forecasting

Beyond helping people plan their weekends, ecological forecasts will improve decision-making in agriculture, forestry, fisheries and other industries. They will help private landowners, local governments and state and federal agencies better manage and conserve our land, water and coastlines, for example by warning of events such as pest outbreaks and harmful algal blooms.","It can happen immediately using existing data, often with only modest reframing of the questions asked and the approaches taken. Ecological forecasting would benefit from cyberinfrastructure for the automation, public dissemination, and archiving of ecological forecasts, which will allow community advances in two important ways. First, by looking across different types of forecasts, we can take a comparative approach to understanding what affects predictability in ecology.","[4.0, 5.0, 3.0, 2.0]",Computer_Science,train,3.5,news,http://ct.moreover.com/?a=33155403240&p=1pl&v=1&x=1LQtI2Kyk1DqizQ_djubiQ
10.1098/rspb.2014.1195,Computer_Science_464,"Alistair Sutcliffe, expert in systems engineering at the University of Manchester said, ""The novelty in this study is the differentiation between social and antisocial lying.","The results of our study suggest that not all lies are bad or necessarily socially destructive; in fact, it seems that some lies may even enhance the cohesion of the society as a whole and help to create links with other people.","Barrio and his team observed that introducing more fibbing in the network reduced the number of undecided agents and concluded prosocial lying actually help people make up their mind. Alistair Sutcliffe, expert in systems engineering at the University of Manchester said, ""The novelty in this study is the differentiation between social and antisocial lying. In reality the tolerance to fibbing depends on the strength of the relationship.""","Although we are taught from an early age that lying is unacceptable, children nonetheless learn to lie wisely instead of eschewing it completely. The results of our study suggest that not all lies are bad or necessarily socially destructive; in fact, it seems that some lies may even enhance the cohesion of the society as a whole and help to create links with other people. In effect, some kinds of lies might actually be essential to the smooth running of society, and if so, the balance between pro-and antisocial lies may be crucial in shaping social structure.","[4.0, 4.0, 5.0, 2.0, 3.0]",Computer_Science,train,3.6,news,http://www.realclearscience.com/articles/2014/07/30/white_lies_make_social_networks_stronger_108769.html
10.1126/scirobotics.aar4423,Computer_Science_465,That makes the microswimmer ever more robust and flexible than others.,"Moreover, the RBC microswimmers preserved their integrity when deformed inside the microchannels and collected at the outlet (Fig.","Rather, it's more like a moveable snap hook system, which attaches the two parts  with Avidin in the middle. That makes the microswimmer ever more robust and flexible than others. (Image: Max Planck Institute for Intelligent Systems)

Thirdly, Yunus Alapan continues, we loaded the RBC with special molecules that can absorb infrared light.","RBC microswimmers were able to deform inside the microchannels and pass through with ease (Fig. Moreover, the RBC microswimmers preserved their integrity when deformed inside the microchannels and collected at the outlet (Fig. The percentage of RBC microswimmers before injection (fabrication yield, ~72% of the total RBC population) did not decrease significantly (twotailed t test, P > 0.05) after squeezing through the microchannels (~50%) (Fig.","[5.0, 4.0, 2.0, 3.0]",Computer_Science,train,3.5,news,http://ct.moreover.com/?a=33894382390&p=1pl&v=1&x=F2ZTnfhtJXFI9ZVTsX7MeA
10.1126/scirobotics.aag2048,Computer_Science_466,"Salto's robotic vertical jumping agility is 1.75 meters per second, which is higher than the vertical jumping agility of a bullfrog (1.71 meters per second) but short of the vertical jumping agility of the galago (2.24).","The vertical jumping agility for the 10-W/kg case does not increase substantially with this gain in jump height, which is fundamentally limited to a vertical jumping agility of 1.0 m/s {10 W/[(1 kg) 9.81 m s −2 ]}, the equivalent constant-speed elevator limit.","Salto's robotic vertical jumping agility is 1.75 meters per second, which is higher than the vertical jumping agility of a bullfrog (1.71 meters per second) but short of the vertical jumping agility of the galago (2.24). Adapting this process to Salto enabled its high vertical agility, including the wall jump. By using power modulation, Salto doesn't need to wind up before a jump; as soon as it jumps, Salto is ready to jump again.","Increasing the MA ratio increased the jump height for SE+MA systems. The vertical jumping agility for the 10-W/kg case does not increase substantially with this gain in jump height, which is fundamentally limited to a vertical jumping agility of 1.0 m/s {10 W/[(1 kg) 9.81 m s −2 ]}, the equivalent constant-speed elevator limit. The 100-W/kg system sees substantial gains in agility as the MA ratio is increased; the SE+MA actuator allows more energy to be delivered.","[2.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.futurity.org/salto-robot-vertically-agile-1315102-2/
10.1016/j.chb.2014.05.036,Computer_Science_467,"""Decreased sensitivity to emotional cues is one of the costs--understanding the emotions of other people.","Implications are that the short-term effects of increased opportunities for social interaction, combined with time away from screen-based media and digital communication tools, improves a preteen's understanding of nonverbal emotional cues.","With online training courses being used for almost everything now, this new study may give teachers, parents and administrators pause on such widespread use of digital media in education. ""Decreased sensitivity to emotional cues is one of the costs--understanding the emotions of other people. The displacement of in-person social interaction by screen interaction seems to be reducing social skills.""","After five days interacting face-to-face without the use of any screen-based media, preteens' recognition of nonverbal emotion cues improved significantly more than that of the control group for both facial expressions and videotaped scenes. Implications are that the short-term effects of increased opportunities for social interaction, combined with time away from screen-based media and digital communication tools, improves a preteen's understanding of nonverbal emotional cues. Indeed, one longitudinal study found that the amount of non-screen playtime decreased 20% from 1997 to 2003, while screen activities (i.e., watching television, playing videogames and using the computer) increased .","[4.0, 2.0, 4.0]",Computer_Science,train,3.333333333333333,news,http://time.com/3153910/why-access-to-screens-is-lowering-kids-social-skills/
10.1145/3025453.3025762,Computer_Science_468,The seemingly limitless imagination that can be applied to VR porn experiences could potentially open the door to a whole world of new sexual experiences.,"Through our analysis, we demonstrate a narrative of a 'perfect', idealised sexual experience, as well as one which emphasised the imagined 'precarious' and dangerous consequences around this technology use.","Shutterstock

Some stories illustrated a perfect scenario that completely immersed Jack in a euphoric sexual experience that was ""beyond his wildest dreams"". The seemingly limitless imagination that can be applied to VR porn experiences could potentially open the door to a whole world of new sexual experiences. But some of the stories also portrayed Jack's experience as precarious, something so good that it started to take over his life or replace his real relationships.","Through our analysis, we demonstrate a narrative of a 'perfect', idealised sexual experience, as well as one which emphasised the imagined 'precarious' and dangerous consequences around this technology use. We indicate how the stories reproduced ideals around heteronormativity and hegemonic masculinity, suggesting an agenda of 'Designing for Eroticism' as a tactic which could avoid such problematic discourses. We also suggest the opportunities and challenges presented through use of the 'Story Completion Method'.","[4.0, 2.0, 5.0, 2.0, 3.0]",Computer_Science,train,3.2,news,http://www.realclearscience.com/articles/2017/05/22/the_uncertain_future_of_virtual_reality_porn_110284.html
10.1140/epjb/e2018-90532-7,Computer_Science_469,The authors find an overlap of 60% for the top 100 universities.,"The largest number of top universities is in US but we see a significant numbers also for India, Japan, Germany and France for PageRank which characterizes the university influence.","Thus, they provide a more balanced view that reflects the standpoints of different cultures. The authors find an overlap of 60% for the top 100 universities. They believe, therefore, that the new ranking is a reliable alternative that attaches greater significance to universities' historical development.","In total for all 24 editions we find 1011 and 1464 different universities with PageRank and CheiRank algorithms respectively. The largest number of top universities is in US but we see a significant numbers also for India, Japan, Germany and France for PageRank which characterizes the university influence. The communicativity is highlighted by CheiRank with top countries being US, India, Japan, France and China.","[4.0, 2.0, 4.0, 1.0, 3.0]",Computer_Science,train,2.8,news,http://ct.moreover.com/?a=38376731042&p=1pl&v=1&x=Riw-7jplJPtlUuSehFfTQA
10.1098/rstb.2008.0288,Computer_Science_47,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","These effects can be positive and negative, with increased expertise and grey matter volume in some brain regions occurring in tandem with decreased performance on other tasks and decreased grey matter volume in neighbouring brain areas. Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition.","[3.0, 2.0, 5.0, 2.0, 3.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1111/j.1083-6101.2007.00367.x,Computer_Science_470,"On the other hand, if future power and influence rests with those wealthy teens, and they withdraw from Facebook, it may be one more way society is fragmenting, with the better-off seeking more exclusive ways to network.",H4b: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's satisfaction with life.,"As well-to-do teens leave Facebook, they will no longer benefit from those tools. On the other hand, if future power and influence rests with those wealthy teens, and they withdraw from Facebook, it may be one more way society is fragmenting, with the better-off seeking more exclusive ways to network. Facebook's algorithms do tend to expose users primarily to the lives and interests of those they are closest to, but nonetheless offers a window from time to time into the lives of other friends who are more distant.","H4a: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's self esteem. H4b: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's satisfaction with life. Particularly significant changes in social networks may affect one's social capital, as when a person moves from the geographic location in which their network was formed and thus loses access to those social resources.","[2.0, 2.0, 2.0, 4.0, 2.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=37403441412&p=1pl&v=1&x=G6PRN_vwrtG5wHSvwkuGIA
10.1016/j.jocs.2010.12.007,Computer_Science_472,"This research and Andy Haldane's comments suggest that both the music and lyrics of popular songs can indeed be used to predict economic sentiment, and even short-term stock market movements.","For example, shows how online chat activity predicts book sales.","This type of evidence strongly suggests that music consumers' states of mind do have a bearing on what music they choose to pay for and listen to. This research and Andy Haldane's comments suggest that both the music and lyrics of popular songs can indeed be used to predict economic sentiment, and even short-term stock market movements. Calling for economists to consult the musical mood of the nation may seem somewhat surprising, bizarre even.","This may conceivably also be the case for the stock market. For example, shows how online chat activity predicts book sales. Although news most certainly influences stock market prices, public mood states or sentiment may play an equally important role.","[3.0, 1.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.8,news,http://ct.moreover.com/?a=34016848568&p=1pl&v=1&x=Zi9zktZOUNhwpUT-PtNnqA
10.1073/pnas.1617258113,Computer_Science_473,That would put RDS on firm ground as one of the few methods to study vulnerable groups.,This process mimics that found in Goel and Salganik's assessment of RDS using the same Project 90 data (13).,"""That makes it very difficult to make inferences or draw conclusions about these 'hidden' groups."" That would put RDS on firm ground as one of the few methods to study vulnerable groups. But this is not possible when social or legal issues act as barriers between researchers and subjects.","Project 90. This process mimics that found in Goel and Salganik's assessment of RDS using the same Project 90 data (13). It should be noted that although these are simulation studies from a network, the network itself was not simulated.","[3.0, 2.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/zj7FqVF2ipE/
10.1073/pnas.1403657111,Computer_Science_474,"A taxi-share system would likely do the opposite, decreasing the amount of money New Yorkers spend on cabs.","For instance, an 80% rate of shared trips translates into a 40% reduction of the taxi fleet.","On the whole, they increase the size of the taxi industry. A taxi-share system would likely do the opposite, decreasing the amount of money New Yorkers spend on cabs. New York's taxi fleet is busy -- yellow cabs are vacant only 25 percent of the time -- but the projected 40 percent drop in cab mileage produced by a modest ride-share scheme could presumably render several thousand Manhattan cabs obsolete.","Since a shared trip can be served by a single taxi instead of two, the number of shared trips can be used as a proxy for the reduction in number of circulating taxis. For instance, an 80% rate of shared trips translates into a 40% reduction of the taxi fleet. Other important objectives such as total system cost and emissions are reasonably approximated by criterion b).","[5.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://www.salon.com/2014/09/07/how_to_save_america_from_cars_start_sharing_them/
10.1038/nature17941,Computer_Science_475,"The work of Kremkow and colleagues indicates that the organization of all maps originates from the same principle: an arrangement of thalamic afferents that minimizes differences in spatial position, eye input and light/dark polarity among neighboring cortical neurons.",This distinct arrangement of ON and OFF inputs enables continuity in the mapping of both orientation and visual space and the generation of a columnar map of absolute spatial phase.,"Neurons responding to similar stimulus orientations also clustered forming a map with a pinwheel pattern that was discovered later by other scientists. The work of Kremkow and colleagues indicates that the organization of all maps originates from the same principle: an arrangement of thalamic afferents that minimizes differences in spatial position, eye input and light/dark polarity among neighboring cortical neurons. Moreover, they show that the organization of visual space, for both monocular and binocular vision, is more precise for darks than lights.","As a result, cortical columns exhibit an invariant aggregate receptive field structure: an OFF-dominated central region flanked by ON-dominated subfields. This distinct arrangement of ON and OFF inputs enables continuity in the mapping of both orientation and visual space and the generation of a columnar map of absolute spatial phase. 1a, b ), A large fraction (42%) of the layer 2/3 neurons that showed statistically significant receptive fields in response to this stimulus (see Methods) had spatially offset ON and OFF subfields, consistent with the organization of simple cells that has been described in other species.","[2.0, 3.0, 1.0, 4.0, 1.0]",Computer_Science,train,2.2,news,http://www.science20.com/news_articles/scientists_discover_a_surprising_central_role_of_darks_in_brain_visual_maps-171473
10.3389/frobt.2016.00072,Computer_Science_476,The simple game demonstrates one way that novel information from artificial sensors or computer-generated virtual worlds can be successfully encoded and delivered noninvasively to the human brain to solve useful tasks.,"As seen in Figure 10 , no significant correlation exists between maze index and the probability that an error occurred on a turn [Pearson r = 0.04, t(12) = 0.15, p = 0.88].","The five test subjects made the right moves in the mazes 92 percent of the time when they received the input via direct brain stimulation, compared to 15 percent of the time when they lacked that guidance. The simple game demonstrates one way that novel information from artificial sensors or computer-generated virtual worlds can be successfully encoded and delivered noninvasively to the human brain to solve useful tasks. The test subjects also got better at the navigation task over time, suggesting that they were able to learn to better detect the artificial stimuli.","Specifically, the probability of an error occurring on a turn should be higher in the later mazes than in the earlier ones. As seen in Figure 10 , no significant correlation exists between maze index and the probability that an error occurred on a turn [Pearson r = 0.04, t(12) = 0.15, p = 0.88]. Our results suggest that human subjects can learn to interpret the information delivered via non-invasive brain stimulation to solve a task in a virtual world.","[1.0, 1.0, 2.0, 2.0]",Computer_Science,train,1.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/fXDiotkrTV8/
10.1016/j.neuroimage.2016.10.029,Computer_Science_477,"""This tells us that, for the most part, the language we happen to learn to speak does not change the organization of the brain,"" said Marcel Just, the D.O.","Furthermore, the activation patterns corresponding to some of these NPSFs are largely similar across speakers of different languages (e.g.","The findings can be used to improve machine translation, brain decoding across languages and, potentially, second language instruction. ""This tells us that, for the most part, the language we happen to learn to speak does not change the organization of the brain,"" said Marcel Just, the D.O. Knowing this means that brain to brain or brain to computer interfaces can probably be the same for speakers of all languages,"" Just said.","(See Table S .1. in the Supplemental materials for a complete list of the NPSFs and the coding of some sample concepts). Furthermore, the activation patterns corresponding to some of these NPSFs are largely similar across speakers of different languages (e.g. and among bilinguals and monolinguals (e.g.","[1.0, 4.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JuI8qnXRmq4/
10.1140/epjds/s13688-014-0031-z,Computer_Science_478,"The findings show the extent to which communities outside of Boston expressed their emotions by using hashtags such as #PrayForBoston and how those reactions correlated with geographic proximity, social-network connections, and direct ties to Boston.",The distinct nature of these hashtags makes it likely that there are geographic differences in their use.,"The study is the first large-scale analysis of fear and social-support reactions from geographically distant communities following a terrorist attack. The findings show the extent to which communities outside of Boston expressed their emotions by using hashtags such as #PrayForBoston and how those reactions correlated with geographic proximity, social-network connections, and direct ties to Boston. The full results of the study, which have been published online in the journal EPJ Data Science, may provide insight to governmental agencies exploring how to best handle public fear following a disruptive event.","This analysis thus confirms that the two hashtags, when used independently, were used to convey different meanings. The distinct nature of these hashtags makes it likely that there are geographic differences in their use. In particular, while the generic nature of sympathy (as expressed by #prayforboston) might not have any geographic specificity, expressions of solidarity (using #bostonstrong) would be expected from cities with deeper ties to Boston that include shared regional or cultural identities.","[4.0, 3.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.6,news,http://www.sciencedaily.com/releases/2014/12/141211142616.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1111/tops.12078,Computer_Science_479,"When the computer ""read"" only so much, its performance on cognitive tests resembled that of a young adult.","Once the cost of processing this extra information is controlled for in studies of human performance, findings that are usually taken to suggest declining cognitive capacities can be seen instead to support little more than the unsurprising idea that choosing between or recalling items becomes more difficult as their numbers increase.","In fact, basic principles suggest that older adults exhibit greater sensitivity to the nuances of test items than younger adults, and for this reason, their comparative performance on tests may shine a little less brightly. When the computer ""read"" only so much, its performance on cognitive tests resembled that of a young adult. But when the same computer read as much as a human might over a lifetime, its performance appeared more like that of an older adult.","Given that the models run (and can be rerun) on computers, the possibility that any differences in their performance are due to aging hardware can be eliminated; instead, their patterns of performance reflect the information-processing costs that must inevitably be incurred as knowledge is acquired. Once the cost of processing this extra information is controlled for in studies of human performance, findings that are usually taken to suggest declining cognitive capacities can be seen instead to support little more than the unsurprising idea that choosing between or recalling items becomes more difficult as their numbers increase. We suggest that the answer to this question lies in the way that psychometric tests neglect learning and its relationship to the statistical patterns that characterize human experience.","[1.0, 2.0, 3.0, 2.0, 1.0]",Computer_Science,train,1.8,news,http://www.medicaldaily.com/are-older-brains-wiser-aging-brains-slower-due-more-knowledge-and-experience-not-cognitive-decline
10.1098/rstb.2008.0288,Computer_Science_48,"Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others.","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus.","The successful trainees did not perform better on all tests of memory, however. Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others. She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training.","These effects can be positive and negative, with increased expertise and grey matter volume in some brain regions occurring in tandem with decreased performance on other tasks and decreased grey matter volume in neighbouring brain areas. Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition.","[4.0, 2.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1098/rsos.160007,Computer_Science_480,"""Focus both limits the cognitive costs of task switching, and lowers communication and coordination barriers, since so much work is being accomplished by one or only a few individuals,"" the scholars think.",1A) both display truncation and significant rollover.,"Groups, which members have one particular function, tend to achieve much better results. ""Focus both limits the cognitive costs of task switching, and lowers communication and coordination barriers, since so much work is being accomplished by one or only a few individuals,"" the scholars think. Nonetheless, the scientists admit that this success formula is not universal.","We present results that demonstrate (i) how teams distribute work activity across their members, (ii) the mixture of experiential diversity and collective leadership roles in teams, and (iii) how high-impact teams are different from other teams. 1A) both display truncation and significant rollover. Teams were relatively small, with only 0.46% of teams having M > 10 members.","[1.0, 1.0, 1.0, 2.0, 5.0]",Computer_Science,train,1.0,news,http://www.technology.org/2014/07/14/ensures-success-group-github-case/
10.1111/jcc4.12162,Computer_Science_481,"The important thing is that someone, such as a close friend, takes the time to personalize it.","Respondents noted the importance of seemingly trivial interactions, such as sharing jokes or videos: ""I post funny cat videos to her wall and she writes on my wall counting down the days until we're in the same town and get to see each other.""","""This can be a comment that's just a sentence or two. The important thing is that someone, such as a close friend, takes the time to personalize it. The content may be uplifting, and the mere act of communication reminds recipients of the meaningful relationships in their lives.""","Certainly much of the composed communication on Facebook may still be trivial but generate perceived support. Respondents noted the importance of seemingly trivial interactions, such as sharing jokes or videos: ""I post funny cat videos to her wall and she writes on my wall counting down the days until we're in the same town and get to see each other."" ""His comments are hilarious, we get to trade jabs online.""","[3.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/jjMQ9mmdbGA/
10.1038/srep45898,Computer_Science_482,Single neurons in the brain are able to convey much more information than was previously thought and can interact to generate potentially super rich representations of sensory stimuli.,"Such complementariness could allow for co-operative decoding within a small population of neurons, which together might provide a much higher capacity to segregate spatiotemporal patterns of tactile afferent input.","""We were able to measure the cooperation between neural networks in a very precise and detailed way. Single neurons in the brain are able to convey much more information than was previously thought and can interact to generate potentially super rich representations of sensory stimuli. ""This knowledge will be embodied into a novel generation of sensitive robotic hands able to convey fine tactile information to amputees, says lead bioroboticist Calogero Oddo.","2E) , this hinted at the possibility of complementary decoding between neurons. Such complementariness could allow for co-operative decoding within a small population of neurons, which together might provide a much higher capacity to segregate spatiotemporal patterns of tactile afferent input. The temporal spike response patterns could be widely different between two adjacent neurons ( Fig.","[2.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.25,news,http://healthmedicinet.com/news/finger-prosthesis-provides-clues-to-brain-health/
10.1016/j.softx.2018.07.004,Computer_Science_483,"""This feature allows system users to complete more complex tasks like looping and conditional branching.""","Finally, it allows developers implementing Items and Actions to specify, by contract, what is required before proceeding to the next task, processing the workflow, or declaring a successful execution.","""In ICE you can have humans in the loop, meaning the program can stop, ask questions and receive instructions before resuming activity,"" Billings said. ""This feature allows system users to complete more complex tasks like looping and conditional branching."" Combining the best features of grid workflows with modeling and simulation workflows would allow scientists to address even greater challenges and solve scientific mysteries more efficiently.","Second, by formalizing state and error checks, ICE explicitly delineates which workflows can be executed from those that must receive additional configuration. Finally, it allows developers implementing Items and Actions to specify, by contract, what is required before proceeding to the next task, processing the workflow, or declaring a successful execution. Most file I/O in ICE, with only a few exceptions, interacts with the RCP's resources plugin.","[5.0, 1.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=37123443168&p=1pl&v=1&x=xrMy8Ueh0AvFN8FFHuGkzQ
10.1177/1461444816660784,Computer_Science_484,"Facebook is not going to change what it does with the data gleaned from your posts in the ""privacy"" of its own servers--a capacity central to its ad-driven business model.","Zuckerberg suggests that Facebook helps put users in contact with the communities around them, both physical and online:","The thing we'd all just allowed into our lives started feeling menacing, and the companies that made it started damage control. Facebook is not going to change what it does with the data gleaned from your posts in the ""privacy"" of its own servers--a capacity central to its ad-driven business model. But even so, Zuck's new tagline offers a surprising insight by contrast: The future might or might not be private.","Despite attempts to move from a US-centric college-based user to a global conception of the user, then, Zuckerberg's descriptions of site profiles still reflect a normative idea typical of certain kinds of individuals in affluent liberal societies-an idea further reinforced by Zuckerberg's depiction of himself as the prototypical Facebook user (ZF2009g). Zuckerberg suggests that Facebook helps put users in contact with the communities around them, both physical and online: (ZF2009d) It's been amazing to see how all of you have used our tools to build a real community.","[3.0, 1.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=39166701042&p=1pl&v=1&x=DtZm_SIS3iPK8aLt3wmDOQ
10.1073/pnas.1322355111,Computer_Science_486,Recognising that human emotional life is far more complex than a small set of emotions is an important first step in improving technology at the human-machine interface.,"For when one suffers anything, one becomes as if one has the kind of expression: when one is angry, the sign of the same class is angry.","The algorithm was highly successful at identifying the basic emotion expressions (96.86% correct) and slightly less successful at identifying the compound emotion expressions (76.91% correct). Recognising that human emotional life is far more complex than a small set of emotions is an important first step in improving technology at the human-machine interface. Demonstrating that computers can be trained to identify more complex emotion expressions speaks to the potential ability of computers to, at some point in the future, recognise what we are communicating with our faces - but a number of critical questions remain.","We show that these differences are sufficient to distinguish between the 21 defined categories. For when one suffers anything, one becomes as if one has the kind of expression: when one is angry, the sign of the same class is angry. (1) A s nicely illustrated in the quote above, for centuries it has been known that many emotional states are broadcasted to the world through facial expressions of emotion.","[3.0, 2.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.0,news,http://www.technology.org/2014/04/03/happily-disgusted-show-face/
10.1126/science.aam6808,Computer_Science_487,"By the end of the same period, the hippocampal engram cells became silent and were no longer needed for natural recall.","S7 ), in line with previous findings of a positive correlation between the dendritic spine density of memory engram cells and memory expression triggered by natural recall cues (24) (25) (26) .","Over the next two weeks, the silent memory cells in the prefrontal cortex gradually matured, as reflected by changes in their anatomy and physiological activity, until the cells became necessary for the animals to naturally recall the event. By the end of the same period, the hippocampal engram cells became silent and were no longer needed for natural recall. However, traces of the memory remained: Reactivating those cells with light still prompted the animals to freeze.","We also found that the spine density of the PFC engram cells on day 12 was significantly higher than on day 2 (Fig. S7 ), in line with previous findings of a positive correlation between the dendritic spine density of memory engram cells and memory expression triggered by natural recall cues (24) (25) (26) . Cell body inhibition of the PFC engram cells by green light during retrieval did not affect recent memory (day 2); however, at the remote time point (day 12), memory retrieval was disrupted compared with the green light-off condition (Fig.","[4.0, 2.0, 2.0, 4.0, 1.0]",Computer_Science,train,2.0,news,http://news.mit.edu/2017/neuroscientists-identify-brain-circuit-necessary-memory-formation-0406
10.1038/s41598-018-25433-5,Computer_Science_488,"After being exposed to the same layouts and patterns, the time it took to find the letters became faster, even if the target was located behind the viewer's field of vision.","RT for the explicit layout was shorter than for novel ones, even at the first epoch (t(54) = 3.38, p < 0.001).","Your mom was right; she really could tell what was going on behind her back. After being exposed to the same layouts and patterns, the time it took to find the letters became faster, even if the target was located behind the viewer's field of vision. ""Which shows that visual processing is not limited to the visual field, but extends to a wider field around the viewer,"" the researchers said in a statement.","The learning effect of the explicit layout was found at earlier epochs. RT for the explicit layout was shorter than for novel ones, even at the first epoch (t(54) = 3.38, p < 0.001). The explicit layout was also tested in the recognition experiment, and the recognition rate was 74.5% (±5.93% SE), confirming explicit knowledge of the layout (the percentage was statistically larger than 50% (t(54) = 4.13, p < 0.001).","[3.0, 4.0, 1.0, 4.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34059180528&p=1pl&v=1&x=ODA1XqyfKXJ2JZpAGDDW0w
10.1007/s10055-018-0346-3,Computer_Science_49,"Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","Virtual Reality helped patients recall old memories by providing new stimuli difficult to achieve, due to ill health, or inaccessible within a secure environment. They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[4.0, 3.0, 5.0, 3.0, 3.0]",Computer_Science,train,3.6,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1038/s41928-018-0175-0,Computer_Science_490,"""We were able to implement digital control over intensity and frequency of the light being emitted, and the devices are very miniaturized, so they can be implanted under the scalp.",The program states can include all desired experimental protocols for the implant.,"advertisement

Taking More Control and Less Space

""With this research, we went two to three steps further,"" Gutruf said. ""We were able to implement digital control over intensity and frequency of the light being emitted, and the devices are very miniaturized, so they can be implanted under the scalp. We can also independently stimulate multiple places in the brain of the same subject, which also wasn't possible before.""","A method for one-way communication introduced here circumvents these problems. The program states can include all desired experimental protocols for the implant. The hardware requirement for this protocol is minimal, as the only facilities needed in the microcontroller are a non-volatile memory and a set of timers.","[4.0, 2.0, 4.0, 4.0, 4.0]",Computer_Science,train,3.6,news,http://ct.moreover.com/?a=38139242613&p=1pl&v=1&x=6BlLkWEv4-7ZMqXJARy33A
10.1038/s41560-018-0290-1,Computer_Science_491,"""This depends on hosts of factors, from the markets for energy and the characteristics of the batteries themselves.",The congestion-relief application is similar to that of the energy time shift.,"To make a real impact, you need think beyond the lab,"" said Meng. ""This depends on hosts of factors, from the markets for energy and the characteristics of the batteries themselves. Our work is a step in better understanding the link between these two aspects.""","The time-shift application in the DAM works by charging the ESS when the forecasted price of energy is low, and then discharging the ESS when the forecasted price of energy is high . The congestion-relief application is similar to that of the energy time shift. The flexible ramping application accounts for the power fluctuations required to adjust to energy delivery over periods of the order of five minutes .","[2.0, 1.0, 1.0, 3.0, 3.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=37880974785&p=1pl&v=1&x=NDhFST92X_0vwxxfOA1GWw
10.1126/science.aar6404,Computer_Science_492,"Instead, AlphaZero is willing to sacrifice material early in a game for gains that will only be recouped in the long-term.","In chess, AlphaZero defeated Stockfish, winning 155 games and losing 6 games out of 1000 (Fig.","Counterintuitively, AlphaZero also seems to place less value on ""material"", an idea that underpins the modern game where each piece has a value and if one player has a greater value of pieces on the board than the other, then they have a material advantage. Instead, AlphaZero is willing to sacrifice material early in a game for gains that will only be recouped in the long-term. ""Impressively, it manages to impose its style of play across a very wide range of positions and openings,"" says Matthew, who also observes that it plays in a very deliberate style from its first move with a ""very human sense of consistent purpose"".","This demonstrates that a general approach can recover the performance of an algorithm that exploited board symmetries to generate eight times as much data (see fig. In chess, AlphaZero defeated Stockfish, winning 155 games and losing 6 games out of 1000 (Fig. AlphaZero defeated Stockfish in each opening, suggesting that AlphaZero has mastered a wide spectrum of chess play.","[2.0, 5.0, 3.0, 3.0]",Computer_Science,train,3.25,news,http://ct.moreover.com/?a=37913164065&p=1pl&v=1&x=PhEp7KWgMtWvulPBR6JDXg
10.1098/rsos.171920,Computer_Science_493,"In addition to being a source of spiritual guidance for many people around the globe, the Dartmouth-led team saw in the Bible ""a large, previously untapped dataset of aligned parallel text.""",Sentence level alignment of parallel text is needed for many NLP tasks.,"In addition to being a source of spiritual guidance for many people around the globe, the Dartmouth-led team saw in the Bible ""a large, previously untapped dataset of aligned parallel text."" According to the research published in the journal Royal Society Open Science, this is not the first parallel dataset created for style translation. But it is the first that uses the Bible.","This data is highly parallel and high-quality, having been produced by human translators. Sentence level alignment of parallel text is needed for many NLP tasks. The Bible corpus is humanaligned by virtue of the consistent use of book, chapter, and verse number across translations.","[2.0, 2.0, 5.0, 3.0, 1.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=37484251020&p=1pl&v=1&x=8jqisaMCVgVOCZUIyLNGbw
10.1093/cybsec/tyy006,Computer_Science_494,They say these incidents underline why a taxonomy of impacts and harms is so important for businesses.,"To comment briefly on key findings in the 2017 report, the survey highlights that all UK businesses are potentially exposed to cyber-threats.","The full list of cyber harms can be viewed online. They say these incidents underline why a taxonomy of impacts and harms is so important for businesses. By providing a detailed breakdown of the many different ways a cyber-attack can impact a business and third-parties, it gives board members and other senior staff a better understanding of both direct and indirect harms from cyber-attacks when considering the threats their organisation faces.","The report presents statistics about how organizations operate in cyberspace and identifies common types of threat. To comment briefly on key findings in the 2017 report, the survey highlights that all UK businesses are potentially exposed to cyber-threats. They have identified that a sizeable proportion of businesses still lack security controls despite the fact that the vast majority of them have increased their cybersecurity budget.","[1.0, 3.0, 4.0, 1.0, 2.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=37497783613&p=1pl&v=1&x=PF_VSzzTysCHwROhxENy7A
10.1073/pnas.1806108116,Computer_Science_495,"""Compared to a state-of-the-art method, the costs of network fragmentation are 2.5 times lower in our approach, when dismantling a criminal network to 10 percent of its original size,"" says Xiao-Long Ren, doctoral student and first author of the study.","3 , we observe that for the partial dismantling to 50 % of the original GCC size the proposed methodology (NewCut) achieves the same fragmentation level with much smaller cost e.g.","If you remove the middle positions first, you can break up the network more effectively at considerably reduced costs, the researchers state. ""Compared to a state-of-the-art method, the costs of network fragmentation are 2.5 times lower in our approach, when dismantling a criminal network to 10 percent of its original size,"" says Xiao-Long Ren, doctoral student and first author of the study. The criminal network case illustrates another special feature of the ETH approach: unlike other methods, it does not treat all nodes equally.","In Fig. 3 , we observe that for the partial dismantling to 50 % of the original GCC size the proposed methodology (NewCut) achieves the same fragmentation level with much smaller cost e.g. 0.45 (NewCut) vs 0.7 (BPD) for Online Social Petster network, 0.55 (NewCut) vs 0.65 (EGP) for information network of Blogs and 0.61 (NewCut) vs 0.71 for Twitter network (BPD).","[2.0, 4.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=38916617089&p=1pl&v=1&x=QfM0OSghyqvpOzW54-zr_w
10.1016/j.neuroimage.2016.11.034,Computer_Science_496,"According to Jordi Garcia-Ojalvo, group leader of the Dynamical Systems Biology Lab at UPF and collaborator in the study, ""this work shows that the temporal characteristics of the random activity of the brain can have profound effects on its behaviour"".","As previously described , the model can display ""healthy"" or ""epileptiform"" rhythms depending upon its parametrisation and the nature of its input, I ex (see Eq.","""This research provides further insight into ways that communication within brain networks can possibly lead to the occurrence of seizures"" comments Marc Goodfellow, senior lecturer in Mathematics at the University of Exeter and leader of the study. According to Jordi Garcia-Ojalvo, group leader of the Dynamical Systems Biology Lab at UPF and collaborator in the study, ""this work shows that the temporal characteristics of the random activity of the brain can have profound effects on its behaviour"". ""Our findings help to elucidate mechanisms of the generation and spreading of epileptic seizures in the brain.","The factor 2 in front of the integral follows from taking into account power transmitted in both the positive and negative frequency bands. As previously described , the model can display ""healthy"" or ""epileptiform"" rhythms depending upon its parametrisation and the nature of its input, I ex (see Eq. (9)).","[3.0, 3.0, 1.0, 1.0]",Computer_Science,train,2.0,news,http://healthmedicinet.com/news/why-exposure-to-rhythmic-stimulation-at-certain-frequencies-facilitate-epileptic-seizures/
10.1038/s41598-019-41228-8,Computer_Science_497,"In this way, we have greatly simplified the synthesis cycle, enabling high-throughput hardware to achieve highly parallel and fast ""write"" speeds.",The complex combination of these errors -especially deletions and read truncations -causes many strands to be discarded before a decoding attempt is made.,"It's recommended that data on hard drives is fully replaced every decade, so if you have had a set of results sitting safely on a pen drive, it doesn't necessarily mean you will be able to take a look at them (if that's what you like to do) ten or fifteen years down the line. In this way, we have greatly simplified the synthesis cycle, enabling high-throughput hardware to achieve highly parallel and fast ""write"" speeds. BE: We believe that enzymatic DNA synthesis is the optimal way to create a cost-effective, sustainable and scalable integrated system that stores and reads information in DNA.","Figure 2b shows the read error when aligned to the extended adapter and payload sequence. The complex combination of these errors -especially deletions and read truncations -causes many strands to be discarded before a decoding attempt is made. Indeed, of 25,592 reads in this new dataset, 286 aligned well in the −100 to −1 region (score > 400) and contained enough bases to attempt decoding.","[1.0, 1.0, 3.0]",Computer_Science,train,1.6666666666666667,news,http://ct.moreover.com/?a=40364302341&p=1pl&v=1&x=YkjKMnoTZniytD6QvwCSFA
10.1098/rspb.2013.1428,Computer_Science_498,"A dormant skill

""After several weeks of training, the participants in the experiment were able to locate the sources of echoes pretty well.","In the Echolocation experiment, however, the presence of both the lead and the lag strongly affected discrimination.","So the subject can learn to associate the artificial ""echoes"" with the distribution of sound-reflecting surfaces in the simulated space. A dormant skill

""After several weeks of training, the participants in the experiment were able to locate the sources of echoes pretty well. This shows that anyone can learn to analyze the echoes of acoustic signals to obtain information about the space around him.","Second, in the Listening experiment, the presence of the leading source affected discrimination of lagging sources much more than vice versa. In the Echolocation experiment, however, the presence of both the lead and the lag strongly affected discrimination. These data show that the classically described asymmetry in the perception of leading and lagging sounds is strongly diminished in an echolocation task.","[3.0, 2.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2013/08/130829093039.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aab3050,Computer_Science_499,"The work, which appears in the journal Science, marks a significant advance in the field--one that dramatically shortens the time it takes computers to ""learn"" new concepts and broadens their application to more creative tasks.","First, for most interesting kinds of natural and manmade categories, people can learn a new concept from just one or a handful of examples, whereas standard algorithms in machine learning require tens or hundreds of examples to perform similarly.","The work, which appears in the journal Science, marks a significant advance in the field--one that dramatically shortens the time it takes computers to ""learn"" new concepts and broadens their application to more creative tasks. ""Our results show that by reverse engineering how people think about a problem, we can develop better algorithms,"" explains Brenden Lake, a Moore-Sloan Data Science Fellow at New York University and the paper's lead author. ""Moreover, this work points to promising methods to narrow the gap for other machine learning tasks.""","For any theory of First, for most interesting kinds of natural and manmade categories, people can learn a new concept from just one or a handful of examples, whereas standard algorithms in machine learning require tens or hundreds of examples to perform similarly. For instance, people may only need to see one example of a novel two-wheeled vehicle (Fig.","[3.0, 4.0, 2.0, 2.0, 1.0]",Computer_Science,train,2.4,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/bvHMgS1rFRY/
10.1287/mnsc.2016.2500,Computer_Science_5,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","The coefficient for the Bag-Fee indicator variable which indicates one checked bag fee as being implemented, is negative and statistically significant (-1.8701; p<0.0001). This indicates that when the flights encounter departure delays, the implementation of one checked bag fees reduces SpAdj-Departure-Delay by 1.8701 minutes (when a delay occurs) versus no implementation of these fees. In other words, the airlines that implemented the fee for one checked bag saw their departure performance improve, whereas Southwest Airlines experienced a negative impact on its departure performance.","[3.0, 3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.neuroimage.2014.12.086,Computer_Science_501,"""This provides evidence that appropriate instruction can bring out the fundamental understanding of how things work at a deep level,"" said Robert Mason, lead author of the study.","In the case of the instructional materials used here, the neural knowledge representations evolved through distinct states, including an initial state before instruction and three additional states following three types of instruction.","They found that learning how something works is a several-stage process that occurs in different parts of the brain. ""This provides evidence that appropriate instruction can bring out the fundamental understanding of how things work at a deep level,"" said Robert Mason, lead author of the study. ""In the future, teaching to this deep level as measured in terms of brain representations may be applicable to other disciplines and scientific concepts.""","Furthermore, the similarity relations among the neural representations of different systems are driven in part by the similarities among the system descriptions. In the case of the instructional materials used here, the neural knowledge representations evolved through distinct states, including an initial state before instruction and three additional states following three types of instruction. The brain locations that responded consistently to the items during test (thinking) trials (as well as the activation locations during explanation trials) provided evidence for the following states of the representation of knowledge: 0.","[2.0, 3.0, 1.0, 4.0, 1.0]",Computer_Science,train,2.2,news,http://www.techtimes.com/articles/40379/20150317/scientists-discover-how-the-brain-functions-when-learning-how-things-work.htm
10.1098/rsos.150223,Computer_Science_502,The research argues that the key factor is that these incentives are not necessarily applied to everyone who may seem to deserve them.,"However, defectors too could, in principle, punish other defectors, even if this may be regarded as somewhat unfair.","A U Warwick release notes that despite the name, the targeted punishment mechanism can apply to positive or negative incentives. The research argues that the key factor is that these incentives are not necessarily applied to everyone who may seem to deserve them. Rather, rules should be devised according to which only a small number of players are considered responsible at any one time.","In most of the parameter range, cooperation is achieved sooner with ν = 10 than with ν = 1. However, defectors too could, in principle, punish other defectors, even if this may be regarded as somewhat unfair. The dynamics is qualitatively similar to the situation in which only cooperators can punish, the main difference being that global cooperation can, unsurprisingly, ensue from lower levels of punishment per player.","[3.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.0,news,http://www.homelandsecuritynewswire.com/dr20150827-subjecting-countries-to-targeted-punishments-could-tackle-climate-change
10.1126/scirobotics.aat7544,Computer_Science_503,"However, they are not so social that the children feel nervous or anxious about interacting with them,"" he added.",These games provide opportunities for the child not only to understand that the caregiver or the robot has a different perspective but also to practice turn-taking and verbal communication.,"""The best hypothesis that we have is that the robots are social, but not too social,"" Scassellati said. However, they are not so social that the children feel nervous or anxious about interacting with them,"" he added. ""The authors are careful to note several of the current limitations, including the relatively restricted context in which the robot is being used.","To succeed in this game, the child needs to understand the social situations and emotional states of the characters. These games provide opportunities for the child not only to understand that the caregiver or the robot has a different perspective but also to practice turn-taking and verbal communication. Substantial effort was placed into making the system robust and easy to use.","[4.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.75,news,http://ct.moreover.com/?a=34885880400&p=1pl&v=1&x=ji4jPuyklgzRTeeOezfJuw
10.1140/epjds/s13688-017-0128-2,Computer_Science_504,"In Brisbane, the system was found to be 16% more accurate at predicting assaults than current models, 6% more accurate for predicting unlawful entry, 4% better for drug offences and theft and 2% better for fraud prediction.","• Age: while cyber features outperform physical and social features, the difference in predictive power based on accuracy is not large.","In tests on both cities, the system predicted specific types of crime in specific parts of the city better than existing crime prediction models based on crime trends. In Brisbane, the system was found to be 16% more accurate at predicting assaults than current models, 6% more accurate for predicting unlawful entry, 4% better for drug offences and theft and 2% better for fraud prediction. In New York City, it improved prediction accuracy by 4% for theft and drug offences, fraud and unlawful entry, while improving predictions of assault by 2%.","(6) the predictive capacity of individual CPS features differs by demographic group: • Age: while cyber features outperform physical and social features, the difference in predictive power based on accuracy is not large. Table 10 shows the top 5 best performing features.","[4.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37484744471&p=1pl&v=1&x=QzSjiCm9RgR4lLGhiGgFCA
10.1038/s41562-018-0364-x,Computer_Science_505,"Now we can put a figure on the number of places you're likely to go to, and it's way fewer than you'd think.","If this is true for the majority of individuals, the location capacity is conserved at the individual level and hypothesis (1)","Now we can put a figure on the number of places you're likely to go to, and it's way fewer than you'd think. It turns out the mathematics governing the number of places we visit on a frequent basis surprisingly doesn't change all that much - and you spend the majority of your life spread out around 25 places. The numbers showed that over a 24 month period, the students mostly kept to just a handful of locations, defined as an activity space.",", the net gain is consistent with G i = 0. If this is true for the majority of individuals, the location capacity is conserved at the individual level and hypothesis (1) Gi , ≥ 1, the individual capacity must either increase or decrease in time, supporting hypothesis (2).","[2.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=34421118868&p=1pl&v=1&x=MhKbyXOEEBXjWjeLocqonQ
10.1126/science.aam6383,Computer_Science_506,These new reports reinforce the evidence for a rudimentary theory of mind in monkeys.,When mapping the MNS in this way ( fig.,"If the new finding leads to the eventual pinpointing of similar neurocircuitry in humans, it may provide insight into so-called ""theory of mind."" These new reports reinforce the evidence for a rudimentary theory of mind in monkeys. ""By showing that areas of the social-interaction network are closely homologous to the theory of mind network in humans, we suggest that our human theory of mind skill might have evolved from the ability of our monkey kin to read social interactions.""","The classical MNS can be mapped in monkeys with fMRI by using videos of humans grasping objects (16) . When mapping the MNS in this way ( fig. S3B and movie S3) , it colocalized with pAIP and F5 interaction areas (Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,https://www.scientificamerican.com/article/monkeys-have-a-specialized-brain-network-for-sizing-up-others-rsquo-actions/
10.1098/rsos.150152,Computer_Science_507,"And during subsequent rounds of the game, students got faster and more accurate at guessing which word was being created.","The exception was that the distance between the intensity of the vocalization and the target word was a reliable predictor of accuracy, such that smaller distances lead to greater accuracy (z = −2.66, p < 0.","Surprisingly enough, the partners scored better than chance on the first round. And during subsequent rounds of the game, students got faster and more accurate at guessing which word was being created. For example, made-up words for ""up"" had a rising pitch, whereas made-up words for ""down"" had a falling pitch.","With one exception, the same pattern of results was also found for the absolute distance between vocalization and word with respect to each variable separately: iconic distance remained highly reliable (z's < −4.02, p's < 0.001), and shorter variable distances did not predict greater accuracy (z's > 0.59). The exception was that the distance between the intensity of the vocalization and the target word was a reliable predictor of accuracy, such that smaller distances lead to greater accuracy (z = −2.66, p < 0. Across all meanings, there was a moderate negative correlation between the iconic distance to that meaning and its probability of selection, regardless of its correctness (r = −0.30, p < 0.001), and a weaker negative correlation between selection probability and median distance (r = −0.18, p < 0.001).","[2.0, 1.0, 2.0, 5.0]",Computer_Science,train,2.0,news,http://news.sciencemag.org/brain-behavior/2015/08/spoken-language-could-tap-universal-code
10.1038/s41467-019-09542-x,Computer_Science_508,"In addition to discovering hidden states and time steps, the scientists also discovered a tradeoff between the two; the more hidden states there are, the smaller the minimal number of hidden timesteps that are required.","In this sense, our results give the minimal ""hidden computer"" of any physical system that implements a given ""visible computer"", for visible computers that range from a single gate all the way up to the partial function given by running an entire (finite) digital computer until it halts.","The scientists may not have been paying attention to those hidden variables and those hidden timesteps, but they are there, playing a key, behind-the-scenes role in many of the papers those scientists have read, and almost surely also in many of the papers those scientists have written."" In addition to discovering hidden states and time steps, the scientists also discovered a tradeoff between the two; the more hidden states there are, the smaller the minimal number of hidden timesteps that are required. According to co-author Artemy Kolchinsky (Santa Fe Institute), ""these results surprisingly demonstrate that Markov processes exhibit a kind of tradeoff between time versus memory, which is often encountered in the separate mathematical field of analyzing computer algorithms.","Our results even apply to the (partial) function that specifies transitions from a digital computer's initial state to its final state that is given by repeating such passes through the entire computer until it halts . In this sense, our results give the minimal ""hidden computer"" of any physical system that implements a given ""visible computer"", for visible computers that range from a single gate all the way up to the partial function given by running an entire (finite) digital computer until it halts. The results in this paper, as well as those in the companion manuscript , derive novel constraints on informationprocessing in terms of state space and and timestep resources, as well as novel tradeoffs between such resources.","[3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.5,news,http://ct.moreover.com/?a=38999628732&p=1pl&v=1&x=x0KyNxY4F1_GcfHipaKgzQ
10.1038/s41598-018-26200-2,Computer_Science_512,"Dr. Shoji's study has shown that CNN's can be trained to find useful, complex information about tiny particles with vast geological value.","Thus, the CNN might not recognize the small-scale structure of the particles.","This may allow for an additional layer of complexity to the data in the future, providing scientists better tools to determine eruption type such as whether an eruption was phreatomagmatic (like second phase of Eyjafjallajokull eruption in 2010) or magmatic (like flank eruptions of Mt. Dr. Shoji's study has shown that CNN's can be trained to find useful, complex information about tiny particles with vast geological value. To increase the range of the CNN, more advanced magnification techniques, such as an Electron Microscopy, can add color and texture to the results.","Another caveat is that we used relatively low-resolution (50×50 pixel) images to reduce the computational time. Thus, the CNN might not recognize the small-scale structure of the particles. If high-resolution images are used, although the computational time will increase, the effect of detailed morphology may be evaluated more accurately.","[2.0, 2.0, 5.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://ct.moreover.com/?a=34407864039&p=1pl&v=1&x=YGTy4wIRUslGblPsAMD3Dg
10.1002/asi.23200,Computer_Science_514,"They were curious rather than anxious, and that made a big difference.",The creatives described the importance of alertness and assiduity for making connections they might otherwise have missed.,"Increase Your Opportunities Giphy It's simple statistics: if you want to be luckier, you need to broaden your chances. They were curious rather than anxious, and that made a big difference. This shift in perspective matters, sociologist Christina Carter told Nautilus.","It is necessary to ""stop to look at the unusual car parked at the curb, taste the new item on the cafeteria menu, actually listen to your colleague at the office"" (p. 347). The creatives described the importance of alertness and assiduity for making connections they might otherwise have missed. Both of these personal qualities were found to be important for preparing the mind by .","[3.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.75,news,http://ct.moreover.com/?a=38145933080&p=1pl&v=1&x=mjMcx4f_pbJY13bb6cSH3A
10.1073/pnas.1813476116,Computer_Science_515,"These behaviors appear simple, but upon closer inspection, each movement contains its own variety and nuance.","We note that the success of the local linear basis in revealing interpretable worm behavior results in part from the ability to capture oscillations and the interactions between different posture modes, both common components of movement behavior.","Crawling - Not as Simple as it Looks

The model uncovered rich complexity underlying one of the simplest of movements: namely, crawling. These behaviors appear simple, but upon closer inspection, each movement contains its own variety and nuance. ""There are more subtle behavioral states you might not see by eye.""","This can be useful for developing a master repertoire of behaviors ( as well as looking for differences between nematode species or studying perturbations to behavior ( ( . We note that the success of the local linear basis in revealing interpretable worm behavior results in part from the ability to capture oscillations and the interactions between different posture modes, both common components of movement behavior. The eigenvalues of the posture dynamics reflect variability and hint at the presence of flexible control.","[3.0, 2.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=38438654480&p=1pl&v=1&x=ne350OgtscalNkgtqQUs8Q
10.1073/pnas.1308540110,Computer_Science_516,"Saramaki hopes in future research to study larger groups of people over longer periods of time, and to include other forms of communication such as social media.",This provides a unique setting for studying network-level structure and its response to major changes in social circumstances.,"After people leave college, for example, their networks might shrink or ""get more and more frozen"" as time goes on, he suggests. Saramaki hopes in future research to study larger groups of people over longer periods of time, and to include other forms of communication such as social media. The findings ""do suggest a certain 'budget constraint' in the number of ties one might maintain, which has been suggested by studies before, but is still not universally accepted,"" says David Lazer, a network scientist at Harvard University.","Irrespective of the specific mechanisms that act to constrain ego networks, it is reasonable to ask whether such mechanisms shape these networks in similar ways under different circumstances, giving rise to some characteristic features that persist over time despite network spondent burden from recording communication events with their entire ego network is very high and people's accuracy in recalling detailed communication events is known to be limited . This provides a unique setting for studying network-level structure and its response to major changes in social circumstances. More importantly, call record data contain complete timestamped records of all calls made by an ego to alters in their network, rather than just a subset of calls an ego makes to alters who happened to be on the same mobile network as them (as has usually been the case in previous work, e.g.","[3.0, 1.0, 3.0, 1.0]",Computer_Science,train,2.0,news,http://news.sciencemag.org/social-sciences/2014/01/only-thing-constant-about-friendship-may-be-number-your-friends
10.1145/3025453.3025635,Computer_Science_517,"Finally, developers should be cognizant of issues of intersectionality.","We adopt many aspects of Bardzell and Bardzell's Feminist HCI methodology , such as indicating our goals as technologists in our interactions with participants.","These associations, which have significant design implications, may be overlooked if developers do not expand their design process to include perspectives from a range of diverse stakeholders. Finally, developers should be cognizant of issues of intersectionality. Try to be mindful of the complex and diverse needs of your target group.","In our work, we highlight ways in which tracking apps fail to support the marginalized populations of gender and sexual minorities. We adopt many aspects of Bardzell and Bardzell's Feminist HCI methodology , such as indicating our goals as technologists in our interactions with participants. However, our research team's expertise is in personal informatics technology, rather than feminist theory.","[1.0, 3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://ct.moreover.com/?a=39599691811&p=1pl&v=1&x=Nu0XBWOkVPbdNJMgESTmvg
10.1287/mksc.2014.0868,Computer_Science_518,"""Two things about diapers make it a good category,"" Hauser says.",24 This result is consistent with our expectation that frequent buyers of branded diapers are forward looking.,"Thus the results of index strategies resemble those of complex models, but arrive there in a much more direct way. ""Two things about diapers make it a good category,"" Hauser says. ""One is that we can identify people who are new, or haven't been in the category for a while.","The likelihood is significantly better (Vuong test significance is p = 0 0002 in-sample and 0 0429 out-of-sample). 24 This result is consistent with our expectation that frequent buyers of branded diapers are forward looking. Third, the index strategy performs as well as the approximately optimal solution in terms of both in-sample fit and out-of-sample predictions.","[2.0, 4.0, 3.0, 1.0]",Computer_Science,train,2.5,news,http://www.sciencedaily.com/releases/2015/03/150326152323.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.compag.2016.07.028,Computer_Science_52,"Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties.","Second, hyperspectral images are capably of capturing the full spectral signature of plants, allowing more advanced analytical tools such as PLSR for modeling of leaf biochemical properties.","In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward. Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties. ""How to capture all of these dynamic traits is really a challenging task without these high-throughput systems,"" Ge said.","First, using different image bands in the hyperspectral cube, plants can be more accurately segmented from the background and leaves can be accurately distinguished from stems (which is quite challenging with a RGB or NIR image). Second, hyperspectral images are capably of capturing the full spectral signature of plants, allowing more advanced analytical tools such as PLSR for modeling of leaf biochemical properties. Based on these previous knowledges, hyperspectral imaging is suggested as a powerful tool in plant phenotyping to complement RGB analysis (to obtain plant chemical traits in addition to morphological traits).","[3.0, 1.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1089/cyber.2014.0129,Computer_Science_520,"Because women tend to use Facebook more than men, they may take interactions more seriously, explaining why women in the study reported higher Facebook jealousy.","In addition, women were reported to have stronger overall distress reactions.","Women report more Facebook jealousy in general, especially when surveyed, but men report equally or more jealousy when allowed to freely respond to a scenario in their own words. Because women tend to use Facebook more than men, they may take interactions more seriously, explaining why women in the study reported higher Facebook jealousy. The different reactions to emoticon usage, though, might be due to the difference between how men and women perceive infidelity.",", That is, men were far more jealous of cybersex than emotional cheating, whereas women displayed the opposite trend. In addition, women were reported to have stronger overall distress reactions. , This is perhaps due to the logistical nature of romantic communication that takes place over the Internet.","[5.0, 3.0, 4.0, 2.0]",Computer_Science,train,3.5,news,http://www.newswise.com/articles/study-emoticons-make-men-more-jealous-than-women
10.1073/pnas.1800683115,Computer_Science_522,The likelihood of a closed triangle rose as the number of collaborations between each of the pairs increased.,"Second, the projected graph edge weight between nodes u and can increase, which we interpret as an increase in tie strength.","""The application might be which new teams are going to form at a company, or which new groups of friends are going to form, or which new substances will go into combination to form a drug. The likelihood of a closed triangle rose as the number of collaborations between each of the pairs increased. They identified an open triangle between two types of gene inhibitors, and a breast cancer resistance protein inhibitor.","This corresponds to an increase in density in this induced subgraph, e.g., the introduction of the drug Promacta adds an edge in Figure 5B . Second, the projected graph edge weight between nodes u and can increase, which we interpret as an increase in tie strength. For instance, in Figure 5C , the tie strength between Gucci Mane and Young Thug increases after they collaborate on ""Fell. ""","[1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.25,news,http://ct.moreover.com/?a=38266125813&p=1pl&v=1&x=MtTJVObJ7-Hq_tHKmdEACg
10.1073/pnas.1510619112,Computer_Science_523,"Thus, the findings could ""help neuroscientists shed more light on the neural bases of disorders such as schizophrenia and Alzheimer's, "" which are marked by malfunctions in the brain's wiring, Bertolero said.","Moreover, there is a strong spatial correspondence between modules derived from spontaneous neural activity obtained with rs-fMRI and the task-evoked activity in the BrainMap database, and these modules can be linked to broad behavioral domains or to specific groups of related tasks , suggesting that these modules might be dedicated to discrete cognitive functions.","""Our findings show that connector hubs allow for distinct networks to each do their own thing, yet still interact with each other effectively,"" said study lead author Maxwell Bertolero, a Ph.D. student in neuroscience at UC Berkeley. Thus, the findings could ""help neuroscientists shed more light on the neural bases of disorders such as schizophrenia and Alzheimer's, "" which are marked by malfunctions in the brain's wiring, Bertolero said. The more complex the task, in that more networks are required for the job, the greater the activity in the connector hubs, keeping the burden off individual networks, the study found.","As mentioned in the Introduction, the genetic basis of each module is significantly specialized, a necessary condition for each module to have a discrete function that was shaped modularly by natural selection (3). Moreover, there is a strong spatial correspondence between modules derived from spontaneous neural activity obtained with rs-fMRI and the task-evoked activity in the BrainMap database, and these modules can be linked to broad behavioral domains or to specific groups of related tasks , suggesting that these modules might be dedicated to discrete cognitive functions. However, these analyses did not empirically derive discrete cognitive functions from the data in BrainMap that could be linked to specific regions in the brain.","[2.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/q0NgAnE_sns/
10.1007/s13735-018-0154-2,Computer_Science_524,"(Schafer et al, 2013)

One's taste in music has long been seen as a window into one's sense of self, and place in society--Robert Prey

Nostalgic by ARIZONA struck a chord with me for a number of reasons -- it triggered vivid memories of past relationships, imagery from my childhood and noticeably shifted my mood from sombre to grateful.","While novelty should be defined on an individual user level, considering the actual freshness of the recommended items, it is common to use the self-information of the recommended items relative to their global popularity:","Music has the ability to trigger emotional connections unlike anything else. (Schafer et al, 2013)

One's taste in music has long been seen as a window into one's sense of self, and place in society--Robert Prey

Nostalgic by ARIZONA struck a chord with me for a number of reasons -- it triggered vivid memories of past relationships, imagery from my childhood and noticeably shifted my mood from sombre to grateful. Your head is just going to get jammed -- it's all going to become a blur, I would think.","A recommendation list may be accurate, but if it contains a lot of items that are not novel to a user, it is not necessarily a useful list . While novelty should be defined on an individual user level, considering the actual freshness of the recommended items, it is common to use the self-information of the recommended items relative to their global popularity: In order to obtain more accurate information about novelty or freshness, explicit user feedback is needed, in particular since the user might have listened to an item through other channels before.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39868491634&p=1pl&v=1&x=-8XxepVU9EEHfPy0qsIGXg
10.1016/j.neuroimage.2018.09.009,Computer_Science_525,"""The same issues could also apply when we think about interactions between family, friends, colleagues or strangers on a one-to-one basis.","For altruistic giving compared to rest, AI and ACC activity could underlie empathy .","In doing so, charities might also inadvertently replace the warm glow feeling with a sense of having had a bad deal."" ""The same issues could also apply when we think about interactions between family, friends, colleagues or strangers on a one-to-one basis. A hug and kind words however might spark a warm glow and make you feel appreciated.","Finally, these activations could represent different processes in each context. For altruistic giving compared to rest, AI and ACC activity could underlie empathy . More relevant for risky strategic giving , ACC activation could reflect greater ambiguity or risk or an increase in effort and prediction .","[1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.25,news,http://ct.moreover.com/?a=37226454935&p=1pl&v=1&x=wyJxIIY6c0nJLyv8Wpj7SQ
10.1038/s41586-018-0470-y,Computer_Science_526,"Professor Myungshik Kim, Chair in Theoretical Quantum Information Sciences at the U.K.'s Imperial College London, described the study as a ""significant step forward"" in the development of quantum computers.","The Wigner function not only provides a strikingly visual representation of the logical qubit state, but also completely specifies the underlying cavity state, a capability analogous to full state tomography of the constituent physical qubits that compose a logical qubit.","Principal investigator Robert Schoelkopf said: ""It is a milestone toward quantum information processing using error-correctable qubits."" Professor Myungshik Kim, Chair in Theoretical Quantum Information Sciences at the U.K.'s Imperial College London, described the study as a ""significant step forward"" in the development of quantum computers. ""An important breakthrough is that they minimized the use of operations and resources so to reduce imperfections and operating times.","Demonstration of the teleported gate using such a logical encoding offers a practical route for incorporating quantum error-correction protocols in the future. The Wigner function not only provides a strikingly visual representation of the logical qubit state, but also completely specifies the underlying cavity state, a capability analogous to full state tomography of the constituent physical qubits that compose a logical qubit. Any maximally entangled state is acceptable, and the specific choice requires only small modifications to later steps of the teleported-gate protocol.","[4.0, 2.0, 2.0, 1.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=37022274827&p=1pl&v=1&x=CjMfcd26iukadij995nHPA
10.1038/s41551-018-0195-0,Computer_Science_527,"""We hope researchers in other places will take what we have and build on it.""",that the AUC of the model might change if there were different or finer groupings of patients on the basis of length of previous smoking history.,"""I am very excited about what this means for discovery,"" Peng said. ""We hope researchers in other places will take what we have and build on it."" ""Rather than replacing doctors, it's trying to extend what we can actually do.""","In particular, because former smokers were grouped with never-smokers, it is possible that the AUC of the model might change if there were different or finer groupings of patients on the basis of length of previous smoking history. Additional validation of our models on other datasets would be beneficial for all these predictions.","[2.0, 1.0, 4.0, 1.0, 1.0]",Computer_Science,train,1.8,news,http://healthmedicinet.com/news/look-at-this-google-ai-can-predict-heart-disease-by-checking-eyes/
10.1287/mnsc.2016.2500,Computer_Science_53,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance. Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes. Our research also sheds some light on the decisions made by a very operationally focused airline.","[3.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1407887111,Computer_Science_531,But an alliance does not necessarily have to commit itself to a social approach.,We call such ZD strategies fair.,"What is crucial to the shared objective is how many players join forces. But an alliance does not necessarily have to commit itself to a social approach. On the contrary, it can form an extortioner group.","5, such a player enforces the payoff relation π i = π −i , such that i's payoff matches the average payoff of the other group members. We call such ZD strategies fair. As shown in Fig.","[1.0, 2.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://www.sciencedaily.com/releases/2014/10/141030114959.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10994-006-6226-1,Computer_Science_532,"However, if we ask a random sample of 1,000 individuals their opinion on the same topic, we'll tend to have a much more stable final ""group opinion"".","The geometrical analysis has shown that Extra-Trees asymptotically produce continuous, piecewise multi-linear functions.","Conversely, highly complex models will tend to have low bias but higher variance -- they will be extremely sensitive to different noisy perturbations of the data, and adjust parameters to ""refit"" (ie. However, if we ask a random sample of 1,000 individuals their opinion on the same topic, we'll tend to have a much more stable final ""group opinion"". In our previous example, we had 1147 data points (n = 1147).","Furthermore, we have highlighted the different nature of the bias/variance tradeoff in classification and regression problems, explaining why classification problems can take advantage of stronger randomization. The geometrical analysis has shown that Extra-Trees asymptotically produce continuous, piecewise multi-linear functions. The resulting models are thus smoother than the piecewise constant ones obtained with other ensemble methods which optimize the cut-points.","[1.0, 3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://ct.moreover.com/?a=39860217841&p=1pl&v=1&x=H6uaka3HYAmreUgjHSwRuQ
10.1073/pnas.1802407115,Computer_Science_533,But you need to be open to solving tough problems no matter when they happen.,"For example, when looked at through the lens of interaction frequency, the pattern of interaction studied in ref.",Being curious at work shows that you are invested and that you are dedicated to solving every tough problem. But you need to be open to solving tough problems no matter when they happen. And expressing that gratitude makes more of a difference than you might realize.,"Importantly, although past laboratory * Beyond guiding future work, our finding may also permit a reinterpretation of some prior results. For example, when looked at through the lens of interaction frequency, the pattern of interaction studied in ref. may be closer to IT than CT, presenting a possible explanation for the benefits of interaction described in that paper.","[3.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.6,news,http://ct.moreover.com/?a=37757166179&p=1pl&v=1&x=wHSjdFNKmwb7Cyo5h16fWw
10.1073/pnas.1613982114,Computer_Science_534,"""Our results suggest, however, that adults with a fully operational cortex still have a subcortex with the ability to distinguish number, yet it operates on a similar level to what is found in babies, other primates, and lower level species who can make coarse computations of large ratios such as, for example, which shoal of fish is bigger and should be joined.","Mauchly's test indicated that sphericity was violated [X 2 (9) = 23.6; P < 0.01], and therefore, the degrees of freedom were corrected in the linear model using Huynh-Feldt correction (« = 0.80).","""The subcortex is not good at making fine grain number discriminations, and these findings support that,"" Collins says. ""Our results suggest, however, that adults with a fully operational cortex still have a subcortex with the ability to distinguish number, yet it operates on a similar level to what is found in babies, other primates, and lower level species who can make coarse computations of large ratios such as, for example, which shoal of fish is bigger and should be joined. ""This provides evidence of a potential evolutionary bridge between the human adult subcortex and the brain of lower order species.""","Regarding task difficulty, the overall median accuracy and RT were 96.7% and 543.9 ms. Mauchly's test indicated that sphericity was violated [X 2 (9) = 23.6; P < 0.01], and therefore, the degrees of freedom were corrected in the linear model using Huynh-Feldt correction (« = 0.80). A repeatedmeasures ANOVA with ratio and ocularity (monocular/dichoptic) as within-subjects factors and IE as the dependent measure revealed a significant two-way interaction [F (3.2,80) = 2.73; P = 0.04].","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.futurity.org/your-subcortex-might-gauge-numbers-like-a-guppys/
10.1038/s41598-019-40765-6,Computer_Science_536,"The qubits then work in the opposite way, from complex to simple, and therefore order was restored.",where the left hand side does not depend on x 1 and therefore one has to assume a 1 and a 2 to be constant.,"In the first experiment, the qubits became an increasingly complex changing pattern of zeros and ones, which created chaos. The qubits then work in the opposite way, from complex to simple, and therefore order was restored. Scientists were delighted to discover an initial success rate for ""time reversal"" of 85 per cent.","3 the following conditions should hold where the left hand side does not depend on x 1 and therefore one has to assume a 1 and a 2 to be constant. This, however, contradicts the non-separability assumption for ϕ x x ( , ) 1 2 .","[2.0, 4.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38753360902&p=1pl&v=1&x=PhuVglHiHGKXyuNNrsxUoA
10.1016/j.neunet.2019.01.006,Computer_Science_539,"In other words, while the ANN is 'awake', it's learning and storing patterns.","The replica symmetric assumption means that, in the thermodynamic limit N → ∞, the order parameters self-average over their averages (denoted hereafter by a bar), i.e.","And it works very similarly to how it is thought to occur in humans. In other words, while the ANN is 'awake', it's learning and storing patterns. So this is what the ANN's 'sleep' state does too, cycling through and unlearning unnecessary information, and then consolidating what's left, the important stuff.","10 The latter, at least within a biological context, is fixed around O(10 2 ) Hertz, namely the typical spiking time (considering also the absolute refractory period of a biological neuron). The replica symmetric assumption means that, in the thermodynamic limit N → ∞, the order parameters self-average over their averages (denoted hereafter by a bar), i.e. lim N →∞ P (q) = δ(q −q) and lim N →∞ P (m) = δ(m −m), in such a way that the related fluctuations can be discarded.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,news,http://ct.moreover.com/?a=38541296193&p=1pl&v=1&x=vNIr115SVoOIp8Uv_8tTzw
10.1126/scirobotics.aap9770,Computer_Science_540,"advertisement

""A steady, reliable sensory experience could significantly improve a prosthetic user's quality of life,"" Bretl said.","5, A and B) varied in response to the electrode being peeled back and reapplied.","For example, a light touch would generate a light sensation, but a hard push would have a stronger signal. advertisement

""A steady, reliable sensory experience could significantly improve a prosthetic user's quality of life,"" Bretl said. They performed a test where the electrodes were progressively peeled back and found that the control module reduced the electrical current so that the users reported steady feedback without shocks.","R p values (Fig. 5, A and B) varied in response to the electrode being peeled back and reapplied. 5 , C and D) and T (Fig.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33898522283&p=1pl&v=1&x=XJkBXXAiP8x4RG32DODCcA
10.1073/pnas.1719397115,Computer_Science_541,"The glass of water you left on the nightstand when preparing for bed is now partially blocked from your line of sight by your alarm clock, yet you know that it is a glass.","A two-way ANOVA on performance with SOA and masking as factors revealed a significant interaction (F(4) = 42.6, p<10 -8 ).","The glass of water you left on the nightstand when preparing for bed is now partially blocked from your line of sight by your alarm clock, yet you know that it is a glass. In the end, the model provided useful insights towards understanding how to make inferences from minimal information.","When partial objects were followed by a backward mask, performance was significantly impaired (compare Figure 1E versus 1F) . A two-way ANOVA on performance with SOA and masking as factors revealed a significant interaction (F(4) = 42.6, p<10 -8 ). The behavioral consequences of shortening SOA were significantly stronger in the presence of backward masking (compare solid versus dashed lines in Figure 1G after averaging across visibility levels).","[3.0, 1.0, 3.0, 1.0]",Computer_Science,train,2.0,news,http://news.mit.edu/2018/mit-martin-schrimpf-advancing-machine-ability-recognize-partially-seen-objects-0920
10.1038/s41562-019-0541-6,Computer_Science_543,And having different political perspectives ends up being associated with different assumptions about phenomena like climate change.,"Polarized teams may attempt to integrate more diverse information, requiring more talk, which yields greater article quality.","If it's an important page like climate change, then there's going to be an intensive back-end debate. And having different political perspectives ends up being associated with different assumptions about phenomena like climate change. And the fact that people are coming to these kinds of questions with different priors and different assumptions and typically having read different scientific literature ends up meaning that there's an intensive debate.","Diverse information should be more difficult to integrate, particularly if contested. Polarized teams may attempt to integrate more diverse information, requiring more talk, which yields greater article quality. We find that polarized teams generate a larger volume of debate and their balance of political perspectives reduces flare-ups in debate temperature.","[1.0, 1.0, 4.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38717091203&p=1pl&v=1&x=B9dJ2ngQGbOBx5x_KO4J3A
10.1126/scirobotics.aat1853,Computer_Science_544,A foam tube wrapped with a skin was able to inch forward like a worm.,"Further, we show that combining multiple robotic skins enables complex motions and functions.","A foam tube wrapped with a skin was able to inch forward like a worm. And a piece of skin connecting two pieces of cardboard could contract, turning the object into a rudimentary gripper. I'm Delighted I Can Do That, Dave

In unpredictable environments like outer space, where unforeseen problems can arise, this diversity gives the skins a creative advantage over traditional robots that are only designed for a limited amount of activities.","We show that attaching the same robotic skin to a soft body in different ways, or to different soft bodies, leads to distinct motions. Further, we show that combining multiple robotic skins enables complex motions and functions. We demonstrate the versatility of this soft robot design approach in a wide range of applications-including manipulation tasks, locomotion, and wearables-using the same two-dimensional (2D) robotic skins reconfigured on the surface of various 3D soft, inanimate objects.","[4.0, 4.0, 1.0, 4.0]",Computer_Science,train,4.0,news,https://www.nationalgeographic.com.au/science/electronic-skin-creates-robots-from-ordinary-objects.aspx
10.1145/2660267.2660348,Computer_Science_545,"The results of the approach, according to the paper, are ""strong privacy guarantees.""","It is likely that some attackers will aim to target specific users by isolating and analyzing reports from that user, or a small group of users that includes them.","That data can have use for prying governments, malicious hackers and Google itself, but Rappor obscures what's actually going on for a given individual before Google even receives the data. The results of the approach, according to the paper, are ""strong privacy guarantees."" That muddles the ""yes"" responses, and another flip can muddle the ""no"" responses.","This problem could be mitigated to some extent by running collections per account and sharing a common Permanent randomized response. It is likely that some attackers will aim to target specific users by isolating and analyzing reports from that user, or a small group of users that includes them. Since these clients are not contributing any useful information to the collection process, targeting them individually by an attacker is counter-productive.","[1.0, 4.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.6,news,http://www.cnet.com/news/how-google-tricks-itself-to-protect-chrome-user-privacy/
10.1038/srep03472,Computer_Science_546,"As he explains, trying to analyze a large amount of data to seek trends and patterns is similar to what physicists do when examining millions of particles of matter, and trying to understand the nature of all the interactions of the particles and the affects of those interactions.","In a given (large) time interval, an individual can focus on different interests, giving rise to a kind of ''transition'' among the interests.","Those data sets are big enough to eventually give researchers a credible indication of about how much of peoples' decision-making follows patterns, or if it's mostly random and chaotic, Lai says. As he explains, trying to analyze a large amount of data to seek trends and patterns is similar to what physicists do when examining millions of particles of matter, and trying to understand the nature of all the interactions of the particles and the affects of those interactions. Having information on the massive scale provided by big data can enable researchers to get a clearer picture despite the variables and randomness in peoples' decision-making.","An individual can possess a number of interests, which can be ranked in terms of the respective frequencies of visit. In a given (large) time interval, an individual can focus on different interests, giving rise to a kind of ''transition'' among the interests. The interest ranking and transition are important not only for the study of human dynamics 30 and decision-making 46 , but also for applications such as behavior prediction and search-algorithm design.","[1.0, 1.0, 2.0, 4.0, 1.0]",Computer_Science,train,1.8,news,http://www.technology.org/2014/03/13/big-data-reveals-human-interests-behavior/
10.1098/rsif.2009.0386,Computer_Science_547,"Over the next two years, almost 30,000 people in West Africa would be infected with the Ebola virus.","an epidemic), and the growth factor per generation indicates the potential for growth.","Over the next two years, almost 30,000 people in West Africa would be infected with the Ebola virus. And the stakes couldn't be higher. This is why, as with weather forecasting, gathering real-time data is likely essential for advancing the scientific community's ability to predict outbreaks.","In a natural way this leads to viewing the infection process in terms of consecutive 'generations of infected individuals', in complete analogy to demographic generations. an epidemic), and the growth factor per generation indicates the potential for growth. In a natural way this growth factor is then the mathematical characterization of R 0 .","[4.0, 3.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=38546393281&p=1pl&v=1&x=2PdNZGKeh8ajqKzk6KR3Ow
10.1038/s41598-018-27405-1,Computer_Science_548,"But the more we learn about the culture and intellectual capacity displayed by our super freaking intelligent animal relatives like chimps, dolphins, and birds, the less unique human intelligence starts to appear.","Prior to the emergence of stone tools, it is likely that hominin tool behaviour involved a greater proportion of cognitively transparent behaviours , and emulative processes may have played an important role in their transmission .","But the more we learn about the culture and intellectual capacity displayed by our super freaking intelligent animal relatives like chimps, dolphins, and birds, the less unique human intelligence starts to appear. This suggests that crows can form a amental templatea of tools based on other crowsa tools and their own past tools, which would explain why New Caledonian crowsa tools could have improved over time. But the catch was that only certain sized pieces of paper earned a reward.","Here, emulation could be sufficient to enable cultural transmission and evolution. Prior to the emergence of stone tools, it is likely that hominin tool behaviour involved a greater proportion of cognitively transparent behaviours , and emulative processes may have played an important role in their transmission . These findings also raise the possibility that other cases of transparent tool manufacture, such as the varied fishing probes manufactured by chimpanzees 50 , could potentially allow for cumulative cultural evolution.","[4.0, 3.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.6,news,http://ct.moreover.com/?a=34421538103&p=1pl&v=1&x=lR7ERrnWV0SUjXuogl2rsQ
10.1093/database/bat080,Computer_Science_549,Putting the data into the CTD framework helps investigators develop and test hypotheses about how drugs might cause adverse events.,"In total, 9 489 curated articles yielded 38 083 phenotype interactions, of which 31 903 (84%) were for chemical-phenotype, 6% were for gene-phenotype and 10% were for complex chemical-gene-phenotype interactions ( Figure 4B ).","""The project quickly added lots of new data that complements environmental toxicity,"" says Davis. Putting the data into the CTD framework helps investigators develop and test hypotheses about how drugs might cause adverse events. ""Coding the information in a structured format was key,"" insists Davis.","From the drug-phenotype corpus, 36 742 phenotype interactions were curated, and an additional 1 341 interactions came from 401 articles of the drug-disease corpus that were incidentally curated for phenotype information during the transition period between projects (Table 2 ). In total, 9 489 curated articles yielded 38 083 phenotype interactions, of which 31 903 (84%) were for chemical-phenotype, 6% were for gene-phenotype and 10% were for complex chemical-gene-phenotype interactions ( Figure 4B ). Apoptosis was the most frequently curated phenotype, followed by blood pressure, cell proliferation, oxidative stress and cell cycle ( Figure 2D ).","[1.0, 2.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.6,news,http://www.newswise.com/articles/database-tracks-toxic-side-effects-of-pharmaceuticals
10.1038/s41598-018-29429-z,Computer_Science_550,They can also add mass and simulate the effect of being pushed or pulled at different parts of the body.,"Our results suggest that the metabolic cost of walking can largely be explained by the linear combination of four costs-swing and torso dynamics, center of mass velocity redirection, ground clearance, and body weight support.","Humans instinctively adopt the gait that requires the least amount of energy given the walking conditions. They can also add mass and simulate the effect of being pushed or pulled at different parts of the body. Making custom exoskeletons

This pioneering software drew on a number of experiments appearing in recent literature, and it offers a huge number of potential applications -- especially in the medical realm.","added mass), and reduced gravity conditions, without the need for parameter tuning to design new gait trajectories. Our results suggest that the metabolic cost of walking can largely be explained by the linear combination of four costs-swing and torso dynamics, center of mass velocity redirection, ground clearance, and body weight support. The overall energetic cost is a tradeoff among these separable components, shaped by how they manifest under different walking conditions.","[3.0, 1.0, 2.0, 3.0]",Computer_Science,train,2.25,news,http://ct.moreover.com/?a=34904566901&p=1pl&v=1&x=kfCWxMSijOO4IbTt2RSdpw
10.1287/mnsc.2014.1966,Computer_Science_551,"""But losing by a point versus winning by a point, most of that is just noise.","In our model actors primarily follow standard Bayesian updating, but place inordinately more weight on success/failure than other available information about future success.","""A blowout win is informative about the team's future success, compared to a crushing defeat,"" said Brennan Platt, a professor of economics at BYU and co-author on the study. ""But losing by a point versus winning by a point, most of that is just noise. To say 'a win is a win' ignores important information in the intensity of the win, causing narrow losers to overreact and narrow winners to be complacent.""","We also provide a simple theoretical model of outcome bias, which produces behavior consistent with our empirical findings. In our model actors primarily follow standard Bayesian updating, but place inordinately more weight on success/failure than other available information about future success. Additionally, this requires panel data on the strategy and its consequences for multiple periods.","[2.0, 1.0, 5.0, 4.0, 3.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/07/140721182033.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ipm.2016.06.009,Computer_Science_552,City size and population do not appear to factor into how stressed the tweeters are.,This is a particular concern given that this type of tweet is a likely future application of the program.,"San Antonio comes in first on the list at 11.62 percent. City size and population do not appear to factor into how stressed the tweeters are. Corpus Christi, Lubbock, El Paso and Laredo are ranked third through sixth on the list, with similar percentages, circa 11.5 percent.",Its performance was weakest for all metrics on the set of tweets matching stress and relaxation terms. This is a particular concern given that this type of tweet is a likely future application of the program. The low performance on this sub-corpus reflects TensiStrength being likely to classify all tweets as having at least moderate levels of either stress or relaxation and so there would be relatively few easy classifications of texts with no matching terms.,"[2.0, 3.0, 2.0, 2.0, 1.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=39298051140&p=1pl&v=1&x=C8h4-vOrRm5pv6FlfQf6Wg
10.1126/scirobotics.aau3098,Computer_Science_553,This is the stuff of the future.,The role of the physical configuration should be more thoroughly investigated to analyze the limits of what passive mechanical systems can achieve.,"This robotic hand can play a surprisingly accurate rendition of 'Jingle Bells'

By Maddy Shaw Roberts

It can also play some staccato Scarlatti passages. This is the stuff of the future. We might not be seeing the hand mastering a Liszt etude anytime soon, but its rendition of 'Jingle Bells' is surprisingly dexterous.","The proposed architecture can be extended to other application and research directions. The role of the physical configuration should be more thoroughly investigated to analyze the limits of what passive mechanical systems can achieve. In particular, automation of the mechanical design process would enable a more scalable and consistent approach.","[1.0, 1.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.4,news,https://www.classicfm.com/discover-music/instruments/piano/robotic-hand-plays-jingle-bells-scarlatti-piano/
10.1111/j.1083-6101.2009.01474.x,Computer_Science_554,I also notice that many wear their Facebook-hate with pride.,"Using the same approach of entering multiplicative terms in the models for civic and political participation, only one interaction achieved statistical significance: The relationship between intensity of Facebook Groups use and political participation was weaker for white respondents than for minority respondents (β = −.23, p < .05).","They see its superficiality, they frown at the self-promotion, they would rather contact their friends in more meaningful ways, preferring real, close friends to large numbers of acquaintances. I also notice that many wear their Facebook-hate with pride. Or maybe it's more than that - maybe they are sensing something that us users are missing?","No other interactive term in the regression of political participation was statistically significant. Using the same approach of entering multiplicative terms in the models for civic and political participation, only one interaction achieved statistical significance: The relationship between intensity of Facebook Groups use and political participation was weaker for white respondents than for minority respondents (β = −.23, p < .05). Our results provide consistent evidence that these positive associations exist.","[3.0, 1.0, 2.0, 1.0, 2.0]",Computer_Science,train,1.8,news,http://www.theepochtimes.com/n3/1213575-facebook-friend-or-foe/
10.1186/s13040-014-0033-1,Computer_Science_556,"""Our GR can be used by researchers on a daily basis to investigate and characterize the dynamic complexity of living bodies.",Also we show the names of 10 positively and two the most negatively correlated genes.,"""The devised computer algorithm allows the computation of GR for 50 thousand genes and 500 samples within just a few minutes on a personal computer,"" said Demidenko. ""Our GR can be used by researchers on a daily basis to investigate and characterize the dynamic complexity of living bodies. In particular, this will be helpful to characterize malignant tumors.""","The width of the bar is proportional to the gene's correlation coefficient with remaining genes. Also we show the names of 10 positively and two the most negatively correlated genes. As follows from this plot, less correlated genes are at the BPESC1 GSTT1 NLRP2 TCHH PON3 TYRP1 CRYBB2 TP53 TECTA CDH19 PCDHGA9 KCNG2 TDRD1 DDX43 HTR1F RPH3AL NPR3 THSD7A CXORF1 KL DAZL HOXD9 GUCY1B2 LDHAL6B MIA 25 most connected genes HCN2 GRIN1 ELA2 POU3F1 RBMXL2 HNF4A APC2 UTF1 SCRT1 PRDM12 SOX10 CACNA1I PRTN3 CDK5R2 HRH3 SEMA6B SOX1 CSF3 CHAT WNT1 ALX4 OLIG2 ADRB1 ACCN4 bottom and more correlated genes are at the top (the yellow curve represents the density of the squared correlation distribution).","[2.0, 1.0, 3.0]",Computer_Science,train,2.0,news,http://www.sciencedaily.com/releases/2015/02/150213112114.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/science.aav8911,Computer_Science_557,"In other trials, the animals were less confident in their judgments because the interval was closer to the boundary and difficult to discriminate.","In particular, our results suggest that the long latency signals in ACC result from an integration of early error-related modulations in DMFC, much like what is seen in well-established first-order perceptual decision-making tasks between sensory and higher-order association and premotor areas ).","These trials were relatively easy and afforded a high degree of confidence. In other trials, the animals were less confident in their judgments because the interval was closer to the boundary and difficult to discriminate. advertisement

As they had hypothesized, the researchers found that the animals' behavior was influenced by their confidence in their performance.","This result, coupled with an experiment involving simultaneous DMFC perturbation and ACC recording, enabled us to reveal the sequential nature of computations in DMFC and ACC and provided a coherent explanation of their distinct functional link to behavior, their different activation latencies, and their circuit-level interactions. In particular, our results suggest that the long latency signals in ACC result from an integration of early error-related modulations in DMFC, much like what is seen in well-established first-order perceptual decision-making tasks between sensory and higher-order association and premotor areas ). An important outstanding question that our study motivates is the problem of maintaining a desired behavioral strategy between switches, which may involve other brain areas such as the dorsolateral prefrontal cortex .","[2.0, 2.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=39241727390&p=1pl&v=1&x=UDzthXxD76LXX1JfD73f6g
10.1126/scirobotics.aat4983,Computer_Science_558,Researchers found the hardware and low-level software were most prone to error.,"It is also responsible for characterizing the environment in terms of robot configurations abilities, allowing the high-level planner to make decisions regarding reconfiguration.","The team proved the effectiveness of its system with three experiments. Researchers found the hardware and low-level software were most prone to error. The second experiment, for instance, took 24 attempts before succeeding, with the stairs posing a particular challenge.","While our system implementation is built around the SMORES-EP robot, the system architecture could be used with any modular robot capable of self-reconfiguration. It is also responsible for characterizing the environment in terms of robot configurations abilities, allowing the high-level planner to make decisions regarding reconfiguration. Although we implement object recognition by color, more sophisticated methods could be included under the same system architecture.","[2.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.25,news,http://ct.moreover.com/?a=37555978419&p=1pl&v=1&x=aZ2DJc2waVue3i_kc0R0jQ
10.1016/j.csda.2018.06.014,Computer_Science_559,"""We would hope that our algorithms could be used in similar software.""",We showed that the results from these distinct data analysis methods happen to agree very well.,"By making recommendations about where to patrol, the algorithm led to a 7.4 percent reduction in crime. Early conclusions suggest that the upgraded predictive tool could prove superior for coping with the constantly fluctuating world of real-time crime prediction. ""We would hope that our algorithms could be used in similar software.""","For the real-world time-series of gang violence data, the validity of EnPGF is testified by comparing with PF and the ""likely"" parameter region identified by the Kolmogrov-Smirnov statistics. We showed that the results from these distinct data analysis methods happen to agree very well. Nevertheless, our experimental results suggest an issue where EnPGF tends to produce over/under-spreading ensembles for some parameter estimates; hence probabilistically over/under-confidence in the parameter estimates.","[2.0, 2.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=34647930543&p=1pl&v=1&x=LVltVtOm0VTRpZK6PTopiQ
10.1287/mnsc.2016.2500,Computer_Science_56,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Our study provides empirical evidence that the checked baggage fee policies did alter passengers' behavior, yet in a different way than previously postulated. While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance. Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes.","[3.0, 5.0, 2.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2560/11/3/035015,Computer_Science_560,"""There are several brain regions involved in vocalization, but we believe [this one] is important for the learned, voluntary control of speech,"" Chang says.",This result outperforms the joint probability of isolated phoneme prediction and indicates that classification across some words is better than others.,"Chang has taken advantage of the opportunity to study brain activity as these patients speak or listen to speech. ""There are several brain regions involved in vocalization, but we believe [this one] is important for the learned, voluntary control of speech,"" Chang says. By mathematically analyzing these patterns, Chang says, his team showed that ""many key phonetic features"" can be detected.","Although word identification was not sufficient for communication purposes at a mere 18.8%, it is notable that words can be identified from phonemic analysis alone. This result outperforms the joint probability of isolated phoneme prediction and indicates that classification across some words is better than others. It is important to note that we are not strictly decoding words, as we have prior information as to where phonemic onset occurs.","[2.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.0,news,http://www.technologyreview.com/news/528741/a-speech-synthesizer-direct-to-the-brain/
10.1534/genetics.118.301267,Computer_Science_562,"""While we have validated this tool for these three outcomes, we can now apply this method to predict other complex traits related to health risks such as heart disease, diabetes, and breast cancer,"" says Stephen Hsu, lead investigator of the study and vice president for research and graduate studies at Michigan State University.",The SNP heritability of the molecular markers used to build the predictor can be interpreted as an upper bound to the variance that could be captured by the predictor.,"But the applications may not stop there. ""While we have validated this tool for these three outcomes, we can now apply this method to predict other complex traits related to health risks such as heart disease, diabetes, and breast cancer,"" says Stephen Hsu, lead investigator of the study and vice president for research and graduate studies at Michigan State University. ""This is only the beginning.""","However, the total variance accounted for by these SNPs is still a small fraction of the trait heritability and of the proportion of variance that could be captured by regression on common SNPs as suggested by SNP heritability estimates . The SNP heritability of the molecular markers used to build the predictor can be interpreted as an upper bound to the variance that could be captured by the predictor. While identification of GWAS SNPs is accomplished by single SNP regression, construction of a best predictor is a global optimization problem in the high dimensional space of possible effect sizes of all SNPs.","[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,news,https://www.futurity.org/dna-tool-height-health-1881862/
10.1098/rsif.2014.1201,Computer_Science_565,"Ablation works well for simple rhythm disorders with a well-defined hotspot, but is far less effective for complex arrhythmias originating from multiple hotspots that cannot be precisely located with standard imaging techniques.","For example, Figure 4C3 (top row) shows that the high level of information sharing in the central region of the lattice quickly faded as distance between cells increased.","The different types of arrhythmias generated markedly distinct spatial profiles. By contrast, regular EKG tracings of the same rhythm disturbances looked similar with a lot of overlapping features, an observation suggesting that quantifying and digitizing information flow inside the heart would far more reliably distinguish one form of arrhythmia from another. Ablation works well for simple rhythm disorders with a well-defined hotspot, but is far less effective for complex arrhythmias originating from multiple hotspots that cannot be precisely located with standard imaging techniques.","Mutual information was far more spatially heterogeneous than anticipated from the electrical wave propagation. For example, Figure 4C3 (top row) shows that the high level of information sharing in the central region of the lattice quickly faded as distance between cells increased. This reflects the fact that the cells lying along the same electrical wavefront changed over time due to the drifting core.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150310123546.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1145/3128572.3140448,Computer_Science_566,"""We don't know the answers to the questions, and I would argue we don't even know the right questions.","To just obtain the estimated gradients of all pixels, 2p = 536, 406 evaluations are needed.","""This is a new field,"" he adds. ""We don't know the answers to the questions, and I would argue we don't even know the right questions. Andrew and Logan have the brilliance and drive to help lead the way.""","For example, the Inception-v3 network takes input images with a size of 299 × 299 × 3, and thus has p = 268, 203 variables (pixels) to optimize. To just obtain the estimated gradients of all pixels, 2p = 536, 406 evaluations are needed. For a model as large as Inception-v3, each evaluation can take tens of milliseconds on a single GPU, thus it is very expensive to even evaluate all gradients once.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://news.mit.edu/2019/why-did-my-classifier-mistake-turtle-for-rifle-computer-vision-0731
10.1038/s41586-018-0766-y,Computer_Science_567,"To make sense of these results, Bob and Alice share the orientation settings of their apparatus but keep everything else secret.","On the other hand, a TDM based scheme would need only 2N channels.","The rules of quantum mechanics are what allow Alice and Bob to securely generate a shared random number. To make sense of these results, Bob and Alice share the orientation settings of their apparatus but keep everything else secret. All the other results are thrown out.","Lastly, crosstalk between the channels is not harmful, since photons in the wrong channel would, due to the different delay introduced by the WDMs, only contribute to the accidental rate and not be seen as a separate coincidence peak. On the other hand, a TDM based scheme would need only 2N channels. Large scale networks could also combine the advantages of WDMs and TDMs by using both together.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38007597921&p=1pl&v=1&x=T26S97hYMkA6PhpxdHP7bA
10.1145/3152823,Computer_Science_568,"FontCode could be a game changer.""",",r n ).","""We are excited about the broad array of applications for FontCode,"" says Zheng, ""from document management software, to invisible QR codes, to protection of legal documents. FontCode could be a game changer."" PROJECT WEBSITE: http://www.cs.columbia.edu/cg/fontcode/

MORE INFO: http://www.cs.columbia.edu/2018/fontcode-hiding-information-in-plain-text-unobtrusively-and-across-file-types/",", r n ). ,r n ). As discussed above, this decoding function can correct up to n−k 2 incorrectly recognized glyphs in each block.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34019330630&p=1pl&v=1&x=7goUd9Ab35XLPuqTGWlAKQ
10.1073/pnas.1800314115,Computer_Science_569,"For example, employers could use it to design the best shift schedule for their workers by sorting out early birds and night owls, Feinsilver said.",TimeSignature is able to avoid the problems of cross-study renormalization by relying instead on within-subject renormalization.,"""We might be able to predict ahead of time who is at risk of getting sick before they develop symptoms,"" Braun said. This test also could have applications outside medicine. For example, employers could use it to design the best shift schedule for their workers by sorting out early birds and night owls, Feinsilver said.","The TimeSignature algorithm avoids both constraints, yielding a predictor that is more reliable, interpretable, and practical than competing methods. TimeSignature is able to avoid the problems of cross-study renormalization by relying instead on within-subject renormalization. By centering the data for each subject about the daily mean for that gene in that subject, we remove not only batch effects but individual differences in baseline gene expression as well; in effect, we are removing any constitutive differential expression such that our model considers only the time-varying part.","[3.0, 1.0, 1.0, 4.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37072872415&p=1pl&v=1&x=vSViu-CDdX5TOfslXMhpjg
10.1287/mnsc.2016.2500,Computer_Science_57,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Our study provides empirical evidence that the checked baggage fee policies did alter passengers' behavior, yet in a different way than previously postulated. While the reduction in the number of checked bags may indeed have resulted in savings due to lower labor costs for handling checked bags, our findings suggest that the resulting increase in the quantity of bags carried-on may have had a detrimental effect on the airline's costs through a decrease in their on-time departure performance. Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes.","[4.0, 3.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.8,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1038/s41562-019-0597-3,Computer_Science_571,That finding that surprised Nassar.,These data should help to clarify inconsistencies in the literature regarding the relationship between reward learning and memory.,"The researchers also found that participants were equally good at remembering specific images from high value rounds they won when they were tested 5 minutes after the learning task as when they were tested 24 hours later, after a period of memory consolidation. That finding that surprised Nassar. ""We spent quite a bit of time trying to rectify our results with that study because they don't line up.","We show that this role is temporally and computationally precise, independent of consolidation duration (at least in the current paradigm), and contingent on decisionmaking behaviour. These data should help to clarify inconsistencies in the literature regarding the relationship between reward learning and memory. The detailed predictions we have made using these data could be tested in future studies exploring the relationship between dopamine signalling and memory formation.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39175800251&p=1pl&v=1&x=naul6wwrwMo9XFBK7D3MQw
10.1287/msom.2016.0587,Computer_Science_572,Underestimating the value of time in the future could mean an entrepreneur will avoid decisions today that could free up more precious hours down the line.,Our work builds on several streams of literature.,"The authors believe many entrepreneurs undervalue future time. Underestimating the value of time in the future could mean an entrepreneur will avoid decisions today that could free up more precious hours down the line. Rather than muscle through a daily in-box of mostly low-value tasks, for example, an entrepreneur might be smarter to hire someone and delegate that work.","Although mistiming hiring is costly in both entrepreneurial and established firms, the effect may be more severe in entrepreneurial firms because it stunts growth in addition to deferring future profits. Our work builds on several streams of literature. Taking an operations management perspective we derive a simple guideline for how an employee should be valued based on the level of relief s/he provides to the entrepreneur's time constraint.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,news,http://ct.moreover.com/?a=33002496758&p=1pl&v=1&x=qxtPItG_RHRN7XCvN3Q63g
10.1162/jocn_a_00450,Computer_Science_574,"Those regions carry responsibility for alertness and the regulation of cognition required to perform the matching task, the researchers said, in addition to serving a function important to the ""default mode network"" -- a minimum reserve of brain power used to monitor the environment during times of inactivity, or slack.",No classical visual responses were detected in any tests.,"A subsequent functional magnetic resonance imaging scan, while study participants performed a simple sound-matching task while lights flashed in their eyes, showed activation in brain regions believed important that particular task. Those regions carry responsibility for alertness and the regulation of cognition required to perform the matching task, the researchers said, in addition to serving a function important to the ""default mode network"" -- a minimum reserve of brain power used to monitor the environment during times of inactivity, or slack. Under present knowledge of the default network, the theory might explain why the brain's performance improves as light hits those novel photoreceptors -- and might change perception of human ""vision.""","Visual acuity tests previously performed in Boston indicated no light perception in either eye of the three participants. No classical visual responses were detected in any tests. Finally, questionnaire scores indicated that Participants 2 and 3 reported, respectively, relatively poor sleep quality and high propensity to fall asleep during the day (Table 1 ).","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.medicaldaily.com/light-influences-brains-even-blind-improving-cognitive-performance-261155
10.1177/1461444818776611,Computer_Science_575,"You don't want to set it up as this is good and bad, demonizing the users who are posting this content.""",It sounds like you could use some kind words right about now.,"Companies need to weigh not just the content itself, but also the effect that removing it might have on the vulnerable people who share it. You don't want to set it up as this is good and bad, demonizing the users who are posting this content."" New Media & Society

It's an understandable strategy: hashtags, unlike images, can be easily categorized and flagged by automated detection systems and human moderators.","Tumblr's approach to content moderation is different. It sounds like you could use some kind words right about now. We suggest Koko, an anonymous support community made up of nice, caring people like you.""","[1.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34293125712&p=1pl&v=1&x=difd8d3ExzP1c39AL3VuHw
10.1186/s12911-017-0477-6,Computer_Science_576,"The top conditions in each category are stroke, sepsis (a blood infection) and lung cancer, respectively.",This could be a potential barrier to adoption.,"Diagnostic errors leading to death or serious, permanent disability were associated with misdiagnosed cancers (37.8%), vascular events (22.8%) and infections (13.5%) -- categories that the team led by David Newman-Toker, M.D., Ph.D., director of the Johns Hopkins Armstrong Institute Center for Diagnostic Excellence, calls the ""big three."" The top conditions in each category are stroke, sepsis (a blood infection) and lung cancer, respectively. There are over 10 thousand diseases, each of which can manifest with a variety of symptoms, so it can be daunting to think about how to even begin tackling diagnostic problems,"" says Newman-Toker, ""Our findings suggest that the most serious harms can be attributed to a surprisingly small number of conditions.","However, to use the DSS effectively, GPs would need to adapt their consultation style, so that they code more information during rather than at the end of the consultation. This could be a potential barrier to adoption. Training GPs to use the system in a patient-centred way, as well as improvement of the DSS interface itself, could facilitate coding.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39668473091&p=1pl&v=1&x=apDaz3co2stEleeikop6Qw
10.1073/pnas.1812296116,Computer_Science_577,"""It's a very encouraging result which suggests that our paper-based LAMP diagnostics could help deliver better, faster, more effective testing for malaria infections in areas which are currently underserved by available diagnostic techniques.""","Importantly, this sensitivity is above the minimal performance target set out by WHO and FIND .","""Our diagnostic approach correctly diagnosed malaria in 98 percent of the infected samples we tested, markedly more sensitive than both the microscopy and lateral flow tests, which delivered 86 percent and 83 percent respectively,"" Cooper continued. ""It's a very encouraging result which suggests that our paper-based LAMP diagnostics could help deliver better, faster, more effective testing for malaria infections in areas which are currently underserved by available diagnostic techniques."" ""These are challenging environments for any test of this type, with no access to the kinds of refrigeration, special equipment and training that more traditional diagnostic procedures require, so it's very encouraging that the diagnostic techniques we've developed have proven to be so sensitive and reliable,"" said Dr. Reboud.","Taking into account the tests for Plasmodium pan and P. falciparum, the paper-based microfluidic device had a sensitivity of >98% and a coincidence rate of 97% (95% CI, 91.99 to 100%), compared with the test results generated by real-time PCR (Table 1) . Importantly, this sensitivity is above the minimal performance target set out by WHO and FIND . Our method was also more sensitive than the microscopy detection method used (which detected infection in 86% of the tested cases).","[2.0, 2.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.6,news,http://ct.moreover.com/?a=38600474506&p=1pl&v=1&x=HWOsa4H_8JV7dl5rnBa92g
10.1073/pnas.1820672116,Computer_Science_578,"Depending on which material Preston selects, he could design a robot that is index-matched to a specific substance.","signal with a computer-controlled electronic pressure regulator, which proves useful because we demonstrate, through our experiments, that the soft shift register functions as a ""black box"" with interchangeable inputs and outputs; a soft, pneumatic oscillator (7), or a soft button (with a human user; see Fig.","Such energy conservation could be crucial in emergency or disaster situations where the robots travel far from a reliable energy source. Depending on which material Preston selects, he could design a robot that is index-matched to a specific substance. So, if he chooses a material that camouflages in water, the robot would appear transparent when submerged.","When the set input, S, is activated (S = 1), the output becomes 1, even after S returns to 0, exhibiting the ability for data storage within a completely soft device. signal with a computer-controlled electronic pressure regulator, which proves useful because we demonstrate, through our experiments, that the soft shift register functions as a ""black box"" with interchangeable inputs and outputs; a soft, pneumatic oscillator (7), or a soft button (with a human user; see Fig. 8 ) could be used in place of the electronic regulator to generate the clock signal.","[1.0, 3.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.6,news,http://ct.moreover.com/?a=38839930248&p=1pl&v=1&x=-5HwXZcoQq5jg5Exey9hXQ
10.1145/3287560.3287574,Computer_Science_579,These results show that neither part of the argument stacks up.,"Although well defined, this essentially means that the model is fitted to a domain of size 0 and may exhibit large amounts of instability while offering limited predictive power.",This is an important finding. These results show that neither part of the argument stacks up. Many Leavers do have strong preferences between different Leave outcomes.,"In this case, the sensitivity is equivalent to the gradient. Although well defined, this essentially means that the model is fitted to a domain of size 0 and may exhibit large amounts of instability while offering limited predictive power. For unstructured data, such as a count of how many times particular words occur in a document, it makes sense to compare against a baseline created by setting the count to 0.","[1.0, 5.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.0,news,https://www.newstatesman.com/politics/uk/2019/06/everything-you-think-you-know-about-leavers-and-remainers-wrong
10.1073/pnas.1304179110,Computer_Science_580,This means that you can directly study human behaviour in crowds on the web.,The prioritization of various tasks is suggested to lead to a bursty dynamics with power-law distributed waiting times.,This means that you can directly study human behaviour in crowds on the web. He could see that there were periods with relatively steady activity and then there would be a very abrupt and intense upswing in activity. Suddenly there was an event that everyone had to respond to and there was an explosion in the amount of online activity.,"There are information pathways that are not only related to the network topology, but, to a larger degree, correspond to many users tweeting at the same time about the same thing triggered by events outside the network. The prioritization of various tasks is suggested to lead to a bursty dynamics with power-law distributed waiting times. This is in contrast to a homogeneous Poisson process, where the waiting time between tasks that are being selected at random follows an exponential distribution.","[1.0, 1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.2,news,http://www.sciencedaily.com/releases/2013/10/131007151731.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.neuroimage.2018.03.045,Computer_Science_581,"""Our experimental results show that our proposed method outperforms the benchmark methods and achieves much better performance than the state-of-the-art methods in both qualitative and quantitative measures - our method improves the clinical usability, processing speed and encourages less blurring and overall better image quality,"" Dr Zhou said.",This order was necessarily fixed because we need to acquire clinical PET scans first and then the experimental scans.,"The major drawback of dose reduction is that more visual distortion may be involved in the reconstructed PET images, resulting in poor image quality. ""Our experimental results show that our proposed method outperforms the benchmark methods and achieves much better performance than the state-of-the-art methods in both qualitative and quantitative measures - our method improves the clinical usability, processing speed and encourages less blurring and overall better image quality,"" Dr Zhou said. 3D printing was a revelation.","The average time post-injection was 36 min (from 32 to 41 min). This order was necessarily fixed because we need to acquire clinical PET scans first and then the experimental scans. The order, however, creates some implications.","[3.0, 1.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.8,news,http://ct.moreover.com/?a=33755285918&p=1pl&v=1&x=9BBG_ZsWKsgwL4jsAi7jPQ
10.1038/s41562-017-0290-3,Computer_Science_582,An implication of these metrics is that connections are more or less important based on the centrality of the other nodes they connect to.,", (v † , S m )}, such that:","""This matters because, on the one hand, it assists the general public in protecting their privacy against intrusion from government and corporate interests, while on the other hand, it assists counter-terrorism units and law-enforcement agencies in understanding how criminals and terrorists could escape detection, especially given the increasing reliance of terrorists on social media survival strategies."" An implication of these metrics is that connections are more or less important based on the centrality of the other nodes they connect to. Like, if I have a billion Facebook friends but each one of those friends only has one or two friends, then I'm not actually very important in the network, despite the number of connections.","Consequently, our goal is achieved if and only if we add to G a set of edges, A ⊆ {(v † , S 1 ), . , (v † , S m )}, such that: Since we are interested in finding the smallest such subset, a solution to the above instance of the influence recovery problem gives us a solution to the Set Cover problem.","[1.0, 1.0, 4.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33146302013&p=1pl&v=1&x=K16VztVHCEQN3L5t429ZYA
10.1038/s41598-019-39384-y,Computer_Science_583,-- ended up giving KTLA reporter Eric Spillman in downtown Los Angeles a warning that a temblor had begun and shaking was on its way.,This result holds for each of our four cities and the generic uniform random catalog.,"Advertisement

The quake was scary enough that anchors Megan Henderson and Chris Schauble ducked under their desk. -- ended up giving KTLA reporter Eric Spillman in downtown Los Angeles a warning that a temblor had begun and shaking was on its way. Spillman said he felt the ground move seconds later; downtown is farther from Encino than Hollywood is.","The most common outcome the user experiences is the ""correct no alert"" case, reflecting myriad small or distant earthquakes that should not and do not produce significant ground motion at the user's location. This result holds for each of our four cities and the generic uniform random catalog. (Note that the deaggregated frequency of occurrence of this case is shown on log scale in Figs 4-6, S1-S2, because it is so plentiful.)","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,news,http://ct.moreover.com/?a=38611766509&p=1pl&v=1&x=Qld1-mNBIuFmWM61wP3Hmg
10.1145/2998181.2998219,Computer_Science_584,"#myfitnesspal

While the study of Twitter in isolation can reveal insights into users' health status, this research breaks new ground in that the study group consists of individuals who have connected their MyFitnessPal (MFP)--a calorie-counting app--and Twitter accounts.",Our ability to estimate risk of failure can enable timely and tailored deployment of gamification approaches.,"""These users tend to be more anxious seemingly because of a lack of emotional control, and because of certain activities and events of daily life,"" says De Choudhury. #myfitnesspal

While the study of Twitter in isolation can reveal insights into users' health status, this research breaks new ground in that the study group consists of individuals who have connected their MyFitnessPal (MFP)--a calorie-counting app--and Twitter accounts. ""However, considering these data sources together and applying an established causality testing methodology allows us to validate for the very first time the efficacy of social media and quantified self-sensing in revealing risk to diet compliance.""","Gamification is also possible wherein daily diet compliance success/failure can translate to confidence boosting concrete metrics like rewards, points or badges . Our ability to estimate risk of failure can enable timely and tailored deployment of gamification approaches. Additionally, mechanisms could be created on social media platforms to provide socially supportive interventions to individuals at risk of diet compliance failure (e.g., those expressing high NA or high cognitive impairment in their Twitter posts).","[1.0, 3.0, 1.0, 2.0]",Computer_Science,train,1.75,news,http://www.futurity.org/tweets-diet-prediction-1369052-2/
10.1186/1754-1611-3-11,Computer_Science_585,"While the exact source of this new outbreak will probably turn out to be different, the repeated culprit points to shared risks of contamination.","DNA edges flanked by hixC sites can be reshuffled by Hin recombinase, creating random orderings and orientations of edges of the graph.","But not all E. coli is dangerous. While the exact source of this new outbreak will probably turn out to be different, the repeated culprit points to shared risks of contamination. Contaminated salad leaves might seem like something that has only recently grown as an issue.","The design of our bacterial computer benefited from a series of abstractions of DNA sequence into the edges and nodes of a Hamiltonian path. DNA edges flanked by hixC sites can be reshuffled by Hin recombinase, creating random orderings and orientations of edges of the graph. Hin-mediated recombination of the 14 DNA edges could produce 1.42 × 10 15 possible configurations.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37775009283&p=1pl&v=1&x=ske9D8C8sVYfPmhna_iCOA
10.1162/jocn_a_00785,Computer_Science_586,There wasn't any activity in this brain region when the captions were about the person's actions or mathematical equations.,"Finally, individuals who showed stronger dorsomedial PFC activity at baseline in a separate task were generally more efficient when adopting the intentional stance and reported having greater social skills.","When this happened, the participants were able to judge the photos ""significantly faster,"" but only when the next photo contained a caption about the person's mental state. There wasn't any activity in this brain region when the captions were about the person's actions or mathematical equations. ""It is getting us ready to see the world socially in terms of other people's thoughts, feelings, and goals,"" Lieberman said.","Second, moment-to-moment variation in default activity during fixation in the dorsomedial PFC was related to the ease with which participants applied an intentionalbut not nonintentional-stance to a social stimulus presented moments later. Finally, individuals who showed stronger dorsomedial PFC activity at baseline in a separate task were generally more efficient when adopting the intentional stance and reported having greater social skills. These results identify a biological basis for the human tendency to adopt the intentional stance.","[2.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.75,news,http://www.medicaldaily.com/we-go-facebook-work-because-our-brains-are-predisposed-be-social-when-they-need-break-336002
10.1093/bioinformatics/bts686,Computer_Science_587,"In addition to the functionalities available through TCPL, GladiaTOX includes a webservice layer which allows for simple integration with external, third-party systems.","personalized exposure measurements), and results can be updated as more information becomes available or if the underlying assumptions on data integration strategies are modified.","In line with 21st Century Toxicology, GladiaTOX supports the internationally recognized ""3Rs"" of animal research - ""replacement, reduction, and refinement"" - by improving the reproducibility of in vitro HCS studies.5 In addition, since GladiaTOX is able to analyze disparate types of HCS data in an integrated fashion, it supports the ""3S"" approach to biological understanding - ""systematic, systemic, and systems"" - which has been proposed by a team of researchers from institutions including the US Food and Drug Administration, the Center for Alternatives to Animal Testing, and the European Commission Joint Research Centre.6 The 3S approach recommends looking at organisms in their entirety, rather than at specific organs in isolation, through the integration of experimental and computational in vitro systems. In addition to the functionalities available through TCPL, GladiaTOX includes a webservice layer which allows for simple integration with external, third-party systems. It implements a suite of advanced tools for quality control, processing, and reporting, including the exportation of results formatted for the widely used ToxPI graphical user interface.7



""GladiaTOX delivers unprecedented power, efficiency, and reliability in the analysis of in vitro generated HCS data,"" said Julia Hoeng, Ph.D., Director of Systems Toxicology, PMI.","The major advantage of the ToxPi framework stems from its flexibility as diverse types of data can be incorporated (e.g. personalized exposure measurements), and results can be updated as more information becomes available or if the underlying assumptions on data integration strategies are modified. This flexibility comes with the same caveats as with any generally useful analytical tool, whereby users must exercise sound judgment in the numerical representation and intended interpretation of input data.","[1.0, 1.0, 2.0, 3.0]",Computer_Science,train,1.75,news,http://ct.moreover.com/?a=39277494614&p=1pl&v=1&x=EaI2RjLRMD1y-D46nNKpHg
10.1098/rsif.2015.0185,Computer_Science_588,They also don't reveal geographical specificity at a level that statistics derived from cell-phone data would.,"Moreover, we see that laid-off individuals have an additional drop off for a two week period roughly 125 days prior the plant closure.","""I think there are three problems with current government statistics. They also don't reveal geographical specificity at a level that statistics derived from cell-phone data would. He believes that using cell-phone data has the potential to enable more precise and real-time picture of the economy, which would aid in projections and policy decisions.","(c) We see a sharp, sustained drop in the fraction of calls made near the plant by users assigned to the top decile in probability of being unemployed (red) while no affect is seen for the control group users believed to be unaffected (blue). Moreover, we see that laid-off individuals have an additional drop off for a two week period roughly 125 days prior the plant closure. This time period was confirmed to be a coordinated vacation for workers providing further evidence we are correctly identifying laid-off workers.","[1.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.2,news,http://www.theatlantic.com/business/archive/2015/06/what-could-economists-do-with-all-that-cell-phone-data/394442/
10.1145/2996183,Computer_Science_591,The researchers believe that their work could enable police officers to better manage and prepare for both large and small scale disruptive events.,The retweet ratio suggests that other users pick up on event commentaries and propagate them further through the network.,"The new research shows that, on average, the computer systems could pick up on disruptive events several minutes before officials and over an hour in some cases. The researchers believe that their work could enable police officers to better manage and prepare for both large and small scale disruptive events. ""In this research we show that online social media are becoming the go-to place to report observations of everyday occurrences--including social disorder and terrestrial criminal activity.",are good discriminators. The retweet ratio suggests that other users pick up on event commentaries and propagate them further through the network. Another important observation in Figure 5 is that the negative sentiment model outperforms the positive sentiment model in NDCG scores.,"[1.0, 3.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.6,news,http://www.futurity.org/social-media-detect-disruption-1471592/
10.1038/s41586-019-1157-8,Computer_Science_592,"""The approach could be used later in many different fields for evaluating patterns in large quantities of data, for example in medical diagnoses.""","The neurosynaptic system described so far provides the basic structure needed for supervised learning tasks, where the weights of the inputs are set by an external supervisor.","""This integrated photonic system is an experimental milestone,"" says Prof. Wolfram Pernice from Munster University and lead partner in the study. ""The approach could be used later in many different fields for evaluating patterns in large quantities of data, for example in medical diagnoses."" In their study, the scientists succeeded for the first time in merging many nanostructured phase-change materials into one neurosynaptic network.","1c , serves as a building block in layered photonic networks (described below) suited to the scalable implementation of neurosynaptic systems. The neurosynaptic system described so far provides the basic structure needed for supervised learning tasks, where the weights of the inputs are set by an external supervisor. Probe pulses sent to the waveguide lying below the neuronal ring resonator either couple to it or generate an output spike depending, as described previously, on whether the neuronal PCM cell is in the crystalline or amorphous state.","[3.0, 2.0, 4.0, 2.0, 1.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=39176729712&p=1pl&v=1&x=FXADOArIGcPu0W7GGWeMbA
10.1038/s41562-019-0567-9,Computer_Science_595,"Much like in the first portion of the experiment, each generation was able to increase the speed that the wheel traveled at a similar rate.","However, the effects of theory transmission depend on the probability that participants generate useful theories.","""In other words, there was no link between the wheel's performance and the participants' level of understanding,"" Derex said. Much like in the first portion of the experiment, each generation was able to increase the speed that the wheel traveled at a similar rate. But perhaps surprisingly, understanding of the physical system barely changed across the generations, according to the authors, despite the fact that the students could explain the theory to the next participant.","For example, participants who have a correct representation of the wheel dynamics might enhance others' performance by helping them notice the effects of varying specific parameters. However, the effects of theory transmission depend on the probability that participants generate useful theories. If participants produce incorrect theories, theory transmission would prevent individuals from noticing relevant parameters and detrimentally affect their performance.","[1.0, 3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://ct.moreover.com/?a=38893219742&p=1pl&v=1&x=C5qkeMcf4IE4rGSGpSumtQ
10.1016/j.neuroimage.2016.04.011,Computer_Science_596,"Siden omkring midten af 1990'erne har videnskabsfolk vidst, at skaerme far vores hjerner til at opfatte og behandle information anderledes.","It therefore seems likely that the higher the MMT score of a participant, the more effort or attentional top down control was needed when the participant needed to focus on a focal task in the presence of a distractor.","""Prov at sammenligne det med i dag, hvor det gennemsnitlige videoklip med en politiker varer syv eller otte sekunder - hvis vi er heldige - og sa burde forskellen vaere temmelig tydelig."" Siden omkring midten af 1990'erne har videnskabsfolk vidst, at skaerme far vores hjerner til at opfatte og behandle information anderledes. Kun 16 procent mente det modsatte.","Page 28 of 38 this region increased incrementally in response to task difficulty. It therefore seems likely that the higher the MMT score of a participant, the more effort or attentional top down control was needed when the participant needed to focus on a focal task in the presence of a distractor. The current study extends previous findings on media multitasking in three important ways.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34445119790&p=1pl&v=1&x=PNJ3Xli-cLkxpj0dqTis6w
10.1126/scirobotics.aat3818,Computer_Science_597,This could be useful in scenarios in which the prosthetic limb risks being damaged.,"As expected, the epidermal layer was the most activated taxel during loading and absorbed the largest pressure.","""After many years, I felt my hand, as if a hollow shell got filled with life again,"" said the unnamed amputee who tested the e-dermis tech for the team. This could be useful in scenarios in which the prosthetic limb risks being damaged. ""The next steps are a wider range of studies on more amputees and to bring this work to a practical availability to many more amputees.""","The response of the fingertip taxels during object loading captured differences in object curvature based on the relative activation of all sensing elements (Fig. As expected, the epidermal layer was the most activated taxel during loading and absorbed the largest pressure. The sharp edge of object 3 produced a highly localized pressure source on the epidermal layer of the e-dermis, which triggered the neuromorphic nociceptor model (see Materials and Methods) (Fig.","[3.0, 1.0, 4.0, 2.0, 1.0]",Computer_Science,train,2.2,news,http://ct.moreover.com/?a=34373386130&p=1pl&v=1&x=jWLcO9mxhz6A2KQD0nkT1g
10.1073/pnas.1721355115,Computer_Science_598,"The NIST study is the most comprehensive examination to date of face identification performance across a large, varied group of people.","At that time, algorithms performed well with high-quality frontal images of faces with minimal changes in illumination and expression.","""This is the first study to measure face identification accuracy for professional forensic facial examiners, working under circumstances that apply in real-world casework,"" said NIST electronic engineer P. Jonathon Phillips. The NIST study is the most comprehensive examination to date of face identification performance across a large, varied group of people. Neither gets the best results alone.","Combining human and machine face identification judgments also improves accuracy over either one operating alone . At that time, algorithms performed well with high-quality frontal images of faces with minimal changes in illumination and expression. DCNNs can recognize faces from highly variable, low-quality images.","[2.0, 2.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.4,news,http://ct.moreover.com/?a=34178086321&p=1pl&v=1&x=uxX8p0tCFPrpEKmMt4Bgow
10.1098/rsos.180410,Computer_Science_599,"Hence there is a very short window of opportunity for a quantum computer to calculate the private key from the public key and present an alternative signed transaction (for example, making Bob's money go to the thief instead of to Alice).","While the exact duration of t sec may be subject to future discussion, we propose to require hash commitments to be older than six months, i.e.","In fact, we believe that only quantum computers will ever be able to perform this computation. Hence there is a very short window of opportunity for a quantum computer to calculate the private key from the public key and present an alternative signed transaction (for example, making Bob's money go to the thief instead of to Alice). We can think of this attack as analogous to robbing a customer just before he enters a bank to deposit money.","In contrast to previous proposals and discussions [47] [48] [49] [50] , we emphasize the necessity of a sufficiently long delay phase, substantially longer than the standard confirmation period of approximately six blocks in Bitcoin. While the exact duration of t sec may be subject to future discussion, we propose to require hash commitments to be older than six months, i.e. the UTXOs used as input to T reveal must remain unspent during this period.","[4.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34559444245&p=1pl&v=1&x=C_KArHR9HX5gxiazaOfKaw
10.1177/1080569913501862,Computer_Science_6,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings.","Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","Also, higher-income professionals showed lower acceptance for mobile phone use during meetings. Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings. In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region.","[4.0, 4.0, 5.0, 4.0, 5.0]",Computer_Science,train,4.4,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_60,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.",We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West.,"Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.",A possible explanation for more sensitivity to mobile phone use in the Southwest may be the emphasis on hospitality and manners. We are less sure about a possible explanation for lower acceptance for mobile phone behaviors among professionals in the West. We are intrigued by the result that professionals with higher incomes are less accepting of mobile phone use in meetings.,"[5.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.neuroimage.2018.09.045,Computer_Science_600,"The effects were greatest in babies who were fed breast milk for a greater proportion of their time spent in intensive care, the researchers discovered.","Inter-hemispheric connections are shown in blue, and intra-hemispheric connections in magenta.","The study found that babies who exclusively received breast milk for at least three-quarters of the days they spent in hospital showed improved brain connectivity. The effects were greatest in babies who were fed breast milk for a greater proportion of their time spent in intensive care, the researchers discovered. ""Our findings suggest that brain development in the weeks after preterm birth is improved in babies who receive greater amounts of breast milk,"" said Professor James Boardman, director of the Jennifer Brown Research Laboratory at the University of Edinburgh.","75% (a) and !90% (b). Inter-hemispheric connections are shown in blue, and intra-hemispheric connections in magenta. had higher FA in the higher breast milk group.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37180443212&p=1pl&v=1&x=an_mxgHF8up9pfS7XFmr3Q
10.1073/pnas.1800485115,Computer_Science_601,"Women have entered biomedicine in equal numbers to men since the early 2000s, and now represent about 30% of authorship on all research papers (our calculation in forthcoming research), clear evidence of a narrowing gender gap.","The pie of prizes expanded, but a smaller group of scholars received bigger slices.","Interestingly, they also found that women are more likely to win prizes for service to biomedicine than awards for research--50% of these awards went to women from 2008 to 2017, suggesting overrepresentation. Women have entered biomedicine in equal numbers to men since the early 2000s, and now represent about 30% of authorship on all research papers (our calculation in forthcoming research), clear evidence of a narrowing gender gap. Our initial results highlighted overall good news: the proportion of biomedical prizes awarded to women has risen steadily.","1B) , we observe that prizewinning has also become more concentrated within a small set of prizewinners. The pie of prizes expanded, but a smaller group of scholars received bigger slices. This uneven distribution of prizes per scientist is evident along several measures shown in Fig.","[1.0, 1.0, 3.0, 2.0, 1.0]",Computer_Science,train,1.6,news,http://ct.moreover.com/?a=38534749131&p=1pl&v=1&x=FNfHJtZFbGibj4Z7sOFgEw
10.1126/scirobotics.aat5276,Computer_Science_602,"It's not exactly revolutionary, except in that it is extremely simple mechanically -- at depths of thousands of feet, the importance of this can't be overstated -- and non-destructive.",The RAD sampler can unfold to two and a half times its folded,"It's not exactly revolutionary, except in that it is extremely simple mechanically -- at depths of thousands of feet, the importance of this can't be overstated -- and non-destructive. The answer is yes, obviously, since he made it; the details are published in Science Robotics. In testing, the RAD successfully captured some moon jellies in a pool, then at around 2,000 feet below the ocean surface was able to snag squid, octopus and wild jellies and release them again with no harm done.","We anticipate a range of applications beyond interacting with pelagic biological organisms in the ocean. The RAD sampler can unfold to two and a half times its folded diameter, allowing a scaled-up design to use the internal volume of the rocket's payload to achieve a wider aperture.","[1.0, 2.0, 3.0, 1.0]",Computer_Science,train,1.75,news,http://ct.moreover.com/?a=34577083664&p=1pl&v=1&x=13GOG6020VtrxNNygPVN2A
10.1073/pnas.1409770111,Computer_Science_603,"In theory, the highest-modularity set reflects the network's true community structure.","However, in the sparse case we can simplify the effect of non-neighbors, by replacing them with an external field as in [4, 5] .","In theory, the highest-modularity set reflects the network's true community structure. The consensus of many good solutions is better than the 'best' single one."" In community detection, that translates into finding many structures with high modularity while at the same time ensuring that each individual structure is fairly similar to the next.","If ij ∈ E, the BP estimate of the probability that t i = t and t j = s is However, in the sparse case we can simplify the effect of non-neighbors, by replacing them with an external field as in [4, 5] . In that case, we can identify the messages ψ i→k t that i sends to its non-neighbors k with its marginal ψ i t .","[2.0, 2.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.6,news,http://www.technology.org/2014/12/10/better-way-find-communities-networks/
10.1016/j.acalib.2012.11.025,Computer_Science_604,"(Pictured above: Dawnn Karen; C/O: Dawnn Karen)

3.",3 presents the observed average values for each image demographic category.,"Doing so will only make you look misinformed and feel uncomfortable throughout the entire interview. (Pictured above: Dawnn Karen; C/O: Dawnn Karen)

3. Do choose a 'focal accessory'

Many people will advise you to keep it simple -- and there's some truth to that: Wearing something outrageous, even if it makes you feel ultra confident, can backfire by making the interviewer focus on your clothing, instead of your personality.","Bar graphs display the mean approachability rating versus the baseline, with positive values indicating a higher mean approachability rating for the treatment versus baseline, zeros indicating no change, and negative values indicating a lower mean approachability rating for the treatment versus baseline. 3 presents the observed average values for each image demographic category. A significant positive coefficient was observed when grouping all images, and all main effect coefficients were also significant and positive.","[1.0, 3.0, 1.0, 1.0]",Computer_Science,train,1.5,news,http://ct.moreover.com/?a=39984256387&p=1pl&v=1&x=88WbIzHCgOljRyQBW1HqoQ
10.1126/scirobotics.aat4051,Computer_Science_607,If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.,"In addition, through an independent mechanism of a volume-changing electrochemical redox reaction, the shape of the fabricated actuator can be varied, which is of great importance for outdoor applications in which thin-film actuators in general can be sensitive under the ambient conditions.","From a scientific point of view, this nickel hydroxide-oxyhydroxide actuating material is the world's first material system that can be actuated directly by Vis light and electricity without any additional fabrication procedures. This also opens up a new research field on light-induced actuating behaviour for this material type (hydroxide-oxyhydroxides) because it has never been reported before. If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.","The high intrinsic actuating stress and response rate of the material system are comparable to mammalian skeletal muscles. In addition, through an independent mechanism of a volume-changing electrochemical redox reaction, the shape of the fabricated actuator can be varied, which is of great importance for outdoor applications in which thin-film actuators in general can be sensitive under the ambient conditions. The Vis light-induced actuation property of Ni(OH) 2 -NiOOH makes it an important addition to the known group of light-induced artificial muscles that are mainly functional under UV and NIR light, which is more harmful than Vis light.","[1.0, 3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.4,news,http://ct.moreover.com/?a=34236799416&p=1pl&v=1&x=IdYL1zK8-bVE-HK033HtLg
10.1016/j.trc.2019.05.025,Computer_Science_609,"The study included 32 people, 11 of them women.",Preference for AV is another important outcome.,"That's surprising, Roberts says, since trust usually comes with a sense of calm that would suggest decreased anxiety. The study included 32 people, 11 of them women. The ability for automated vehicles to give trust-building advance explanations in the future will depend on better intelligence about road and traffic conditions, Roberts says.","Thus, anxiety should be an outcome used to assess the effectiveness of AV explanations. Preference for AV is another important outcome. If this were true, it would be important to capture preference along with the measures of trust and anxiety.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,https://www.futurity.org/trust-self-driving-car-timing-anxiety-2092272/
10.1098/rstb.2008.0288,Computer_Science_61,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences. Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al. 2000) .","[5.0, 3.0, 5.0, 2.0]",Computer_Science,train,5.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_62,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.",Our research also sheds some light on the decisions made by a very operationally focused airline.,"The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes. Our research also sheds some light on the decisions made by a very operationally focused airline. When the other airlines started charging for one checked bag, Southwest Airlines' decision to not charge for bags went against their high operational service level strategy as their relative departure delay performance initially decreased.","[1.0, 2.0, 2.0, 1.0, 2.0]",Computer_Science,train,1.6,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_63,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","While the correlation of time taxing driving and grey matter volume suggests that the brain changes are acquired and not innate, it could still be argued that the difference in hippocampal volume is instead associated with innate navigational expertise, leading to an increased likelihood of becoming a taxi driver.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","The number of years of navigation experience correlated with hippocampal grey matter volume only in taxi drivers (and not bus drivers who were matched for number of years navigating in London), with right posterior grey matter volume increasing with more navigation experience (figure 3d ). While the correlation of time taxing driving and grey matter volume suggests that the brain changes are acquired and not innate, it could still be argued that the difference in hippocampal volume is instead associated with innate navigational expertise, leading to an increased likelihood of becoming a taxi driver. Despite this group showing a wide range of navigational expertise, there was no association between expertise and posterior hippocampal grey matter volume (or, indeed, Review.","[4.0, 3.0, 3.0]",Computer_Science,train,3.333333333333333,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_64,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.",This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[4.0, 3.0, 4.0]",Computer_Science,train,3.6666666666666665,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1177/1080569913501862,Computer_Science_65,"Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Not surprisingly, younger professionals were more likely to consider various mobile phone behaviors as appropriate during meetings.","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

USC

There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","In the formal meeting setting (see Model 1 in Table 5 ), the following variables were significant predictors: age, income, and region. Not surprisingly, younger professionals were more likely to consider various mobile phone behaviors as appropriate during meetings. Also, higher-income professionals showed lower acceptance for mobile phone use during meetings.","[4.0, 4.0, 2.0]",Computer_Science,train,3.333333333333333,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1287/mnsc.2016.2500,Computer_Science_67,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","At the aggregate level we find that the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. However, charging a fee for both checked bags results in a worse on-time departure performance compared to charging for one checked bag. We also identify the differential impact of baggage fees on 'low-cost' versus 'legacy' carriers: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers when charging for one checked bag.","[4.0, 4.0, 4.0, 1.0, 3.0]",Computer_Science,train,3.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_68,"So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","Our study is the first to show empirically that baggage fees do seem to have influenced customer behavior, and that the effect depends on the type of airline.","This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","Their modeling approach indicates that the way in which airlines have been implementing baggage fees has more direct impact on controlling customer behavior than segmenting customers. Our study is the first to show empirically that baggage fees do seem to have influenced customer behavior, and that the effect depends on the type of airline. Unlike who posit that pricing the baggage separately induces customers to exert effort (i.e., to reduce the volume of checked baggage) and thus lowers the airline's costs, we find that this practice also induces customers to increase the volume of carry-on baggage, which does not lower the airline's costs.","[3.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.5,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_7,"Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.",Our research also sheds some light on the decisions made by a very operationally focused airline.,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.","Our findings highlight factors, such as the effect of carry-on bags, that need to be incorporated in designing incentive schemes. Our research also sheds some light on the decisions made by a very operationally focused airline. When the other airlines started charging for one checked bag, Southwest Airlines' decision to not charge for bags went against their high operational service level strategy as their relative departure delay performance initially decreased.","[3.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_70,"A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region.","Showing these figures and tables can also foster productive conversations about how generation, gender, and status affect perceptions of appropriate mobile phone use in formal and informal settings.","But unlike rudeness among friends, discourteous behavior in the workplace can have real implications for careers, hiring and even workplace efficiency, with tension among coworkers harming productivity. A timely new study co-authored by Peter W. Cardon of the USC Marshall School of Business and colleagues at Howard University is the first to provide an empirical baseline for how attitudes towards mobile phone use actually break down across gender, age and region. Published today in the journal Business Communication Quarterly, the research offers a critical baseline for how attitudes toward technology may change over time and serves as a guide to navigating social expectations around polite smartphone use.","It also equips instructors and trainers with a current set of statistics about norms of civility associated with various mobile phone behaviors in formal and informal meetings. Business communication instructors and trainers can use the tables and figures in this article to help business students and professionals gain awareness of some of the dramatic generational and gender differences. Showing these figures and tables can also foster productive conversations about how generation, gender, and status affect perceptions of appropriate mobile phone use in formal and informal settings.","[5.0, 4.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.8,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10055-018-0346-3,Computer_Science_72,The researchers found that people remember information better if it is presented to them in a virtual environment.,Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[2.0, 2.0, 2.0]",Computer_Science,train,2.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1098/rstb.2008.0288,Computer_Science_75,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.",This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se.,"In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","Despite this group showing a wide range of navigational expertise, there was no association between expertise and posterior hippocampal grey matter volume (or, indeed, Review. This failure to find an association between hippocampal volume and navigational expertise thus suggests that structural differences in the hippocampus of taxi drivers reflect the detail and/or duration of the use of the spatial representation acquired and not innate navigational expertise per se. Clearly, taxi drivers in London have to learn a vast amount of information.","[3.0, 4.0, 2.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_76,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","In the macroscopic case, the notion of how cyclic a process is, has not been deemed important -it was assumed that it was enough to take the initial and final state of the heat engine as being close to the same macroscopic state.","Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","In essence, how cyclic a process is can be understood in terms of how good an approximation ρ in C is to ρ out C . In the macroscopic case, the notion of how cyclic a process is, has not been deemed important -it was assumed that it was enough to take the initial and final state of the heat engine as being close to the same macroscopic state. We find that this is not the case, even if one demands that the initial and final states are arbitrarily close.","[4.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2552/aabc9b,Computer_Science_79,"They had the same clinical benefits with pretty significant energy savings.""",In both patients there were energy savings without worsening of clinical symptoms.,"""We found we could do it without any negative effects in the patients. They had the same clinical benefits with pretty significant energy savings."" It works well, but with limitations,"" Swann says.","We have demonstrated the feasibility of adaptive DBS using a cortical detector sensitive to dyskinesia in two patients. In both patients there were energy savings without worsening of clinical symptoms. This strategy requires further testing in a chronic ambulatory setting, and may be useful in PD patients who are motor fluctuators and experience severe dyskinesia alternating with marked bradykinesia .","[3.0, 3.0, 5.0, 5.0]",Computer_Science,train,4.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1177/1080569913501862,Computer_Science_8,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","In formal meetings, professionals in the West were least accepting of mobile phone use during meetings.","Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings.","Prior to getting the results, we suspected there might be some variation by region. In formal meetings, professionals in the West were least accepting of mobile phone use during meetings. In informal meetings, professionals in the Southwest were least accepting of mobile phone use.","[5.0, 4.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_81,Higher-income professionals had less tolerance for smartphone use in business meetings.,"Interestingly, women are far less accepting of mobile phone use during informal meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Not surprisingly, younger professionals are more accepting of mobile phone use. Interestingly, women are far less accepting of mobile phone use during informal meetings. We also believe region and status affect norms of civility for mobile phone use.","[3.0, 2.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.2,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/978-3-642-55220-5_1,Computer_Science_83,The algorithm they devised stands out from the best algorithms known to date for this problem.,"Compared to existing approaches, and in particular to the line of recent works , the practical relevance of our algorithm is not clear, and will be explored by further work.","Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc. The algorithm they devised stands out from the best algorithms known to date for this problem. Not only is it significantly easier to explain, but its complexity is also considerably improved.","The algorithm presented in this article achieves a significant improvement of the asymptotic complexity of discrete logarithm in finite fields, in almost the whole range of parameters where the Function Field Sieve was presently the most competitive algorithm. Compared to existing approaches, and in particular to the line of recent works , the practical relevance of our algorithm is not clear, and will be explored by further work. We note that the analysis of the algorithm presented here is heuristic, as discussed in Section 5.","[2.0, 4.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.4,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Computer_Science_84,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","This was true even when taxi drivers were compared with another group of navigators, London bus drivers press; see figure 3a,b). While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences. Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al.","[4.0, 5.0, 4.0, 1.0]",Computer_Science,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_85,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","[2.0, 3.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rstb.2008.0288,Computer_Science_87,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","Structural brain changes associated with learning over a time scale of years, however, seem to be restricted to taxi drivers and the acquisition of a large, integrated and complex spatial layout (see for effects relating to short time scales).","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","This suggests that becoming an expert in the domain of memory may be attainable by any of us, with a great deal of time and effort as in the case of taxi drivers, and the use of mnemonics as employed by the memory champions. Structural brain changes associated with learning over a time scale of years, however, seem to be restricted to taxi drivers and the acquisition of a large, integrated and complex spatial layout (see for effects relating to short time scales). Professional musicians were also found to show enhanced judgements of line orientation and three-dimensional mental rotation ability ( ( .","[2.0, 4.0, 4.0, 1.0]",Computer_Science,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/s10055-018-0346-3,Computer_Science_88,"""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says.",This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education. ""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says. ""We believe the future of education and innovation will benefit greatly from the use of these new visual technologies.""","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[3.0, 5.0, 4.0, 4.0]",Computer_Science,train,4.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_89,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.","The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[4.0, 4.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.8,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1287/mnsc.2016.2500,Computer_Science_9,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Thus, the implementation of checked bag fees (a marketing decision) provides an ideal setting to study how an industry changed, or coordinated, their operations to respond to this marketing strategy change. Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","[3.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_90,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","As seen in Table 7 , the other control variables are also statistically significant. Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described. Moreover, the implementation of two checked bags fees policy indicated worse departure performance relative to the implementation of only one checked bag fee, as well as relative to not charging for checked bags.","[3.0, 3.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.2,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_96,"With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace.","The authors concluded that although mobile phone use in meetings is becoming more acceptable, it is still generally considered rude, inappropriate, or distracting during most meetings.","Saying ""Excuse me"" to take a call didn't cut it: over 30 percent still found it to be rarely/never appropriate during informal/offsite lunch meetings. With a national sample of more than 550 full-time working professionals, the study reveals what business professionals perceive as acceptable, courteous or rude use of mobile phones in the workplace. The researchers first identified the most common grievances people had about smartphone use among their colleagues, including browsing the Internet and checking text messages.","Approximately 63% said that they would not text message during meetings. The authors concluded that although mobile phone use in meetings is becoming more acceptable, it is still generally considered rude, inappropriate, or distracting during most meetings. We found that the literature falls short in several ways in identifying how mobile phone behaviors at meetings are perceived as appropriate or not.","[3.0, 4.0, 3.0, 3.0, 2.0]",Computer_Science,train,3.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1080569913501862,Computer_Science_97,"Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Not surprisingly, younger professionals are more accepting of mobile phone use.","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

USC

There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



USC



Those differences are still there, if less pronounced, for more formal meetings:

USC



Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Based on the findings, we have made several basic conclusions. Not surprisingly, younger professionals are more accepting of mobile phone use. Interestingly, women are far less accepting of mobile phone use during informal meetings.","[3.0, 3.0, 5.0, 5.0]",Computer_Science,train,4.0,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1287/mnsc.2016.2500,Computer_Science_98,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","The reductions are significant because departure times and mitigating delays are crucial to so many other facets of the business, such as the number of flights airlines can offer and their image among potential customers. Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","[1.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.25,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1098/rsos.150266,Computer_Science_tweet_0,"Papers with shorter titles get more citations #science #metascience #sciencemetrics
 ",Our analysis suggests that papers with shorter titles do receive greater numbers of citations.,"Papers with shorter titles get more citations #science #metascience #sciencemetrics
 ","length of a paper's title bears no relation to its scientific impact , or that longer titles can be linked to greater citation counts . Our analysis suggests that papers with shorter titles do receive greater numbers of citations. When citation counts are adjusted for the journal in which the paper is published, we find that the strength of the evidence for the relationship between title length and citations received is reduced.","[5.0, 5.0, 2.0, 5.0, 5.0]",Computer_Science,train,5.0,tweets,636458757124440065
10.1002/admt.201700235,Computer_Science_tweet_1,3-D printing was successfully used to create a model of the prostate with the physical properties of prostate tissue. ,"The 3D printed prostate model demonstrated high fidelity with patient organ and tissue in ana tomical, static and dynamic mechanical, hardness, and optical properties.",3-D printing was successfully used to create a model of the prostate with the physical properties of prostate tissue. ,"In summary, we have designed and developed a series of novel methodologies and customized inks for fabricating a 3D printed prostate model with physical properties of tissue and integrated sensing capabilities that can be used for quantitative, advanced surgical rehearsal. The 3D printed prostate model demonstrated high fidelity with patient organ and tissue in ana tomical, static and dynamic mechanical, hardness, and optical properties. Therefore, the prostate model can aid medical pro fessionals to perform more effective preoperative planning and rehearsal and predict organ physical behavior more accurately.","[5.0, 4.0, 4.0, 4.0, 5.0]",Computer_Science,train,4.4,tweets,948962590243377152
10.1038/s41467-019-09542-x,Computer_Science_tweet_10,The minimal hidden computer needed to implement a visible computation. ,"In this sense, our results give the minimal ""hidden computer"" of any physical system that implements a given ""visible computer"", for visible computers that range from a single gate all the way up to the partial function given by running an entire (finite) digital computer until it halts.",The minimal hidden computer needed to implement a visible computation. ,"Our results even apply to the (partial) function that specifies transitions from a digital computer's initial state to its final state that is given by repeating such passes through the entire computer until it halts . In this sense, our results give the minimal ""hidden computer"" of any physical system that implements a given ""visible computer"", for visible computers that range from a single gate all the way up to the partial function given by running an entire (finite) digital computer until it halts. The results in this paper, as well as those in the companion manuscript , derive novel constraints on informationprocessing in terms of state space and and timestep resources, as well as novel tradeoffs between such resources.","[4.0, 3.0, 5.0, 5.0, 4.0]",Computer_Science,train,4.2,tweets,902695929278603264
10.1038/s41598-017-17553-1,Computer_Science_tweet_100,Continuous #radar #tracking illustrates the development of multi-destination routes of bumblebees! A new #nature work @username @username ,"Crystallisation of early legs of the route and a preference for short between-feeder travel distances both have the effect of greatly reducing the vast number of potential route options available and may, under many circumstances, allow bees to alight on a close-to-optimal route in a short space of time.",Continuous #radar #tracking illustrates the development of multi-destination routes of bumblebees! A new #nature work @username @username ,"Our study supports the idea that there are some spatial arrangements of foraging resources for which bumblebee foragers are unable to develop a stable, efficient trapline route. Crystallisation of early legs of the route and a preference for short between-feeder travel distances both have the effect of greatly reducing the vast number of potential route options available and may, under many circumstances, allow bees to alight on a close-to-optimal route in a short space of time. These same heuristics can, however, lead to suboptimal routes under certain conditions such as the array we designed for this experiment.","[4.0, 2.0, 3.0]",Computer_Science,train,3.0,tweets,986908892994179072
10.1098/rspb.2013.1428,Computer_Science_tweet_101,#Echolocation versus echo suppression in #humans.  #scicomm,"In the Echolocation experiment, however, the presence of both the lead and the lag strongly affected discrimination.",#Echolocation versus echo suppression in #humans.  #scicomm,"Second, in the Listening experiment, the presence of the leading source affected discrimination of lagging sources much more than vice versa. In the Echolocation experiment, however, the presence of both the lead and the lag strongly affected discrimination. These data show that the classically described asymmetry in the perception of leading and lagging sounds is strongly diminished in an echolocation task.","[5.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.75,tweets,372777788266524672
10.1509/jppm.14.112,Computer_Science_tweet_102,"Providing calorie information through numbers or icons such as traffic lights, encourages people  to take in fewer c…",Each label type reduced lunch calories by approximately 10%.,"Providing calorie information through numbers or icons such as traffic lights, encourages people  to take in fewer c…","Each label type reduced lunch calories by approximately 10%. Nutrition knowledge was not improved by any menu format. Traffic light labels achieved meaningful reductions in calories ordered even in the absence of numeric information, and the authors found no apparent benefit or detriment of combining label types.","[4.0, 5.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.8,tweets,648195587343560705
10.1016/j.chb.2014.05.036,Computer_Science_tweet_104,"Why You Should Take a Week-Long Break From All Screens 

Read the research:  (login required!)","Implications are that the short-term effects of increased opportunities for social interaction, combined with time away from screen-based media and digital communication tools, improves a preteen's understanding of nonverbal emotional cues.","Why You Should Take a Week-Long Break From All Screens 

Read the research:  (login required!)","After five days interacting face-to-face without the use of any screen-based media, preteens' recognition of nonverbal emotion cues improved significantly more than that of the control group for both facial expressions and videotaped scenes. Implications are that the short-term effects of increased opportunities for social interaction, combined with time away from screen-based media and digital communication tools, improves a preteen's understanding of nonverbal emotional cues. Indeed, one longitudinal study found that the amount of non-screen playtime decreased 20% from 1997 to 2003, while screen activities (i.e., watching television, playing videogames and using the computer) increased .","[4.0, 4.0, 5.0, 4.0, 4.0]",Computer_Science,train,4.2,tweets,504252477454422016
10.1016/j.jcp.2018.12.009,Computer_Science_tweet_105,"New research from @username used #Stampede2 to accurately simulate cell electropermeability, with applications in drug delivery and gene therapy.  ","Remarkably, this representation qualifies for a multi-scale characterization of electropermeabilization.","New research from @username used #Stampede2 to accurately simulate cell electropermeability, with applications in drug delivery and gene therapy.  ","Their description determines the local behavior of each cell membrane under the influence of its surrounding electric potential in a continuous manner. Remarkably, this representation qualifies for a multi-scale characterization of electropermeabilization. However, we note that in practice these models embody calibrations of free parameters that are tuned by experimenting on populations of cells and extending these measurements to single-cell scale, oversighting the multi-scale nature of electropermeabilization in the experiments.","[3.0, 4.0, 2.0, 1.0]",Computer_Science,train,2.5,tweets,1083022806156226561
10.1126/science.aar6404,Computer_Science_tweet_106,"A single #AI algorithm that learns from scratch  to play chess, shoji and Go at superhuman (beyond world champion)  levels
@username by @username David Silver @username and colleagues, editorial by @username @username 
 ","In chess, AlphaZero defeated Stockfish, winning 155 games and losing 6 games out of 1000 (Fig.","A single #AI algorithm that learns from scratch  to play chess, shoji and Go at superhuman (beyond world champion)  levels
@username by @username David Silver @username and colleagues, editorial by @username @username 
 ","This demonstrates that a general approach can recover the performance of an algorithm that exploited board symmetries to generate eight times as much data (see fig. In chess, AlphaZero defeated Stockfish, winning 155 games and losing 6 games out of 1000 (Fig. AlphaZero defeated Stockfish in each opening, suggesting that AlphaZero has mastered a wide spectrum of chess play.","[3.0, 2.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.2,tweets,1070755100568649729
10.1126/science.aam6808,Computer_Science_tweet_107,"My new (co-) 1st author study: ""Engrams &amp; circuits crucial for systems consolidation of a memory""  w/@username ","S7 ), in line with previous findings of a positive correlation between the dendritic spine density of memory engram cells and memory expression triggered by natural recall cues (24) (25) (26) .","My new (co-) 1st author study: ""Engrams &amp; circuits crucial for systems consolidation of a memory""  w/@username ","We also found that the spine density of the PFC engram cells on day 12 was significantly higher than on day 2 (Fig. S7 ), in line with previous findings of a positive correlation between the dendritic spine density of memory engram cells and memory expression triggered by natural recall cues (24) (25) (26) . Cell body inhibition of the PFC engram cells by green light during retrieval did not affect recent memory (day 2); however, at the remote time point (day 12), memory retrieval was disrupted compared with the green light-off condition (Fig.","[2.0, 5.0, 1.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,850043249280602112
10.1073/pnas.1308540110,Computer_Science_tweet_108,#socialbrain The social brain: networks and constraints: makes sense to me ,This provides a unique setting for studying network-level structure and its response to major changes in social circumstances.,#socialbrain The social brain: networks and constraints: makes sense to me ,"Irrespective of the specific mechanisms that act to constrain ego networks, it is reasonable to ask whether such mechanisms shape these networks in similar ways under different circumstances, giving rise to some characteristic features that persist over time despite network spondent burden from recording communication events with their entire ego network is very high and people's accuracy in recalling detailed communication events is known to be limited . This provides a unique setting for studying network-level structure and its response to major changes in social circumstances. More importantly, call record data contain complete timestamped records of all calls made by an ego to alters in their network, rather than just a subset of calls an ego makes to alters who happened to be on the same mobile network as them (as has usually been the case in previous work, e.g.","[1.0, 2.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.2,tweets,200970192208138240
10.1073/pnas.98.2.676,Computer_Science_tweet_110,"“Defining a baseline state in the human brain, arguably our most complex system, poses a particular challenge.” ",This observation is consistent with the hypothesis that the baseline state of these areas is more nearly approximated when subjects rest quietly with their eyes open.,"“Defining a baseline state in the human brain, arguably our most complex system, poses a particular challenge.” ",4) increase their BF when the eyes are opened (details to be published separately). This observation is consistent with the hypothesis that the baseline state of these areas is more nearly approximated when subjects rest quietly with their eyes open. Our study represents a comprehensive analysis of the uniformity of the OEF in the normal human brain while adult subjects are awake and resting quietly with their eyes closed.,"[3.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,849562470096261120
10.1088/1741-2552/aabc9b,Computer_Science_tweet_111,#Parkinsons People | J Neural Eng. 2018 May 9;15(4):046006. doi: 10.1088/1741-2552/aabc9b. [Epub ahead of print]  ,"This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device.",#Parkinsons People | J Neural Eng. 2018 May 9;15(4):046006. doi: 10.1088/1741-2552/aabc9b. [Epub ahead of print]  ,"This strategy requires further testing in a chronic ambulatory setting, and may be useful in PD patients who are motor fluctuators and experience severe dyskinesia alternating with marked bradykinesia . This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device. Lower panels show a zoomed in view to demonstrate that classifier state transitions correspond appropriately to fluctuations in gamma band power.","[1.0, 1.0, 2.0, 1.0, 4.0]",Computer_Science,train,1.8,tweets,1004449894550114305
10.1126/science.aaf2654,Computer_Science_tweet_113,"A study used the ""trolley problem"" with MTurk workers to explore the ideas around autonomous vehicles and ethics. ","Even though people seem to agree that everyone would be better off if AVs were utilitarian (in the sense of minimizing the number of casualties on the road), they all have a personal incentive to ride in AVs that will protect them at all costs.","A study used the ""trolley problem"" with MTurk workers to explore the ideas around autonomous vehicles and ethics. ","Our findings suggests that regulation may be necessary, but at the same time counterproductive. Even though people seem to agree that everyone would be better off if AVs were utilitarian (in the sense of minimizing the number of casualties on the road), they all have a personal incentive to ride in AVs that will protect them at all costs. Accordingly, if both selfprotective and utilitarian AVs were allowed on the market, few would be willing to ride in utilitarian AVs, even though they would prefer others to do so.","[3.0, 4.0, 4.0, 2.0, 2.0]",Computer_Science,train,3.0,tweets,657299151294631936
10.1126/science.aaf2654,Computer_Science_tweet_114,Autonomous vehicles confronted with moral dilemmas ,"When asked whether they would agree to see such moral sacrifices legally enforced, their agreement was higher for algorithms than for human drivers (p < 0.002), but the average agreement still remained below the midpoint of the 0-100 scale in each scenario.",Autonomous vehicles confronted with moral dilemmas ,"As usual, the perceived morality of the sacrifice was high, and about the same whether the sacrifice was performed by a human or by an algorithm (median = 70). When asked whether they would agree to see such moral sacrifices legally enforced, their agreement was higher for algorithms than for human drivers (p < 0.002), but the average agreement still remained below the midpoint of the 0-100 scale in each scenario. Agreement was highest in the scenario where algorithms saved 10 lives, with a 95% confidence interval of 33-46.","[3.0, 4.0, 1.0]",Computer_Science,train,3.0,tweets,655826652019204096
10.1007/s10055-018-0346-3,Computer_Science_tweet_115,"interesting...
#VR  #cognition #recall 

Here's link to research abstract (not an open journal, sadly)  ",This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall.,"interesting...
#VR  #cognition #recall 

Here's link to research abstract (not an open journal, sadly)  ","The HMD condition was found to have 8.8% improvement in recall accuracy compared to the desktop condition, and this was found to be statistically significant. This suggests an exciting opportunity for the role of immersive virtual environments in assisting in recall. Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall.","[2.0, 4.0, 4.0, 1.0, 2.0]",Computer_Science,train,1.0,tweets,1007421806720921600
10.1073/pnas.1322705111,Computer_Science_tweet_118,Higher pitched noises really do come from higher locations in the real world. It's not arbitrary after all! ,"This suggests that all such diverse phenomena, such as the convoluted shape of the outer ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation, ultimately reflect adaptation to the statistics of natural auditory scenes.",Higher pitched noises really do come from higher locations in the real world. It's not arbitrary after all! ,"In this paper we show that pitch borrows its spatial connotation from the statistics of natural auditory scenes. This suggests that all such diverse phenomena, such as the convoluted shape of the outer ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation, ultimately reflect adaptation to the statistics of natural auditory scenes. We find that auditory scene statistics reveals a clear mapping between frequency and elevation.","[4.0, 4.0, 3.0, 1.0, 3.0]",Computer_Science,train,3.0,tweets,454990732424908800
10.1038/s41558-018-0317-4,Computer_Science_tweet_119,The Scenario Database for the @username 1.5°C Report is now available. Go to @username to read all about it  … and then go here for the database  … @username #ipcc #SR15 ,"This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -instead, it shows that pathways with and without BECCS exist for implementing the goals of the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes.",The Scenario Database for the @username 1.5°C Report is now available. Go to @username to read all about it  … and then go here for the database  … @username #ipcc #SR15 ,"A number of scenarios show that limiting global warming to 1.5 °C can be achieved without the deployment of BECCS, while the majority of scenarios use it (Fig. This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -instead, it shows that pathways with and without BECCS exist for implementing the goals of the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes. Although it is often easier to communicate single numbers rather than ranges, the full breadth of indicators or trajectories within a scenario set carries important information about the available options (Fig.","[3.0, 1.0, 2.0]",Computer_Science,train,2.0,tweets,1051931174581485568
10.1021/acscentsci.9b00055,Computer_Science_tweet_120,"#JustAccepted Read research on how deep reinforcement learning optimizes a retrosynthetic strategy with user-defined pathway cost by John S. Schreck, @username &amp; @username from @username @username! 



#openscience ","Looking forward, we anticipate that the retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts.","#JustAccepted Read research on how deep reinforcement learning optimizes a retrosynthetic strategy with user-defined pathway cost by John S. Schreck, @username &amp; @username from @username @username! 



#openscience ","This approach is conceptually similar to the first iteration of AlphaGo introduced by DeepMind. Looking forward, we anticipate that the retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts. in the SMILES string).","[3.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,1134489913171144705
10.1073/pnas.1721355115,Computer_Science_tweet_121,"Interesting new study on face recognition accuracy: ""The best machine performed in the range of ... professional facial examiners. However, optimal face identification was achieved only when humans and machines worked in collaboration."" ","At that time, algorithms performed well with high-quality frontal images of faces with minimal changes in illumination and expression.","Interesting new study on face recognition accuracy: ""The best machine performed in the range of ... professional facial examiners. However, optimal face identification was achieved only when humans and machines worked in collaboration."" ","Combining human and machine face identification judgments also improves accuracy over either one operating alone . At that time, algorithms performed well with high-quality frontal images of faces with minimal changes in illumination and expression. DCNNs can recognize faces from highly variable, low-quality images.","[2.0, 3.0, 2.0, 4.0]",Computer_Science,train,2.75,tweets,1001494792025583616
10.1177/2472555218773086,Computer_Science_tweet_122,"In a new SLAS Discovery article available now for free ahead-of-print, researchers from the Genomics Institute of @username highlight approaches to high-throughput flow cytometry for phenotypic drug discovery.  @username and @username  ",Each of these examples demonstrates the power of flow cytometry when applied in an automated and high-throughput manner.,"In a new SLAS Discovery article available now for free ahead-of-print, researchers from the Genomics Institute of @username highlight approaches to high-throughput flow cytometry for phenotypic drug discovery.  @username and @username  ","The ability to miniaturize the assay to 1536-well format, but still use flow cytometry as a readout, enabled us to screen more compounds while retaining a disease-relevant phenotypic screen. Each of these examples demonstrates the power of flow cytometry when applied in an automated and high-throughput manner. Phenotypic screening allows one to establish a screening assay without a full understanding of all possible molecular mechanisms of action that drive the disease pathology.","[5.0, 2.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.2,tweets,1001901124494987265
10.1016/j.neuroimage.2016.11.034,Computer_Science_tweet_123,"Neuronal tissue displays epileptic-like activity when exposed to stimulation of specific frequencies, by @username  ","As previously described , the model can display ""healthy"" or ""epileptiform"" rhythms depending upon its parametrisation and the nature of its input, I ex (see Eq.","Neuronal tissue displays epileptic-like activity when exposed to stimulation of specific frequencies, by @username  ","The factor 2 in front of the integral follows from taking into account power transmitted in both the positive and negative frequency bands. As previously described , the model can display ""healthy"" or ""epileptiform"" rhythms depending upon its parametrisation and the nature of its input, I ex (see Eq. (9)).","[4.0, 2.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.2,tweets,812717105896427521
10.1002/adma.201706091,Computer_Science_tweet_124,A research team led by Mario Caironi propose tattoo-paper as a platform to integrate electronics onto food or pharmaceutical capsules @username  ,"Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large.",A research team led by Mario Caironi propose tattoo-paper as a platform to integrate electronics onto food or pharmaceutical capsules @username  ,"Inherent edibility may also enable the direct integration of electronic sensors into food in the form of embedded smart probes, following a perishable good along its entire lifespan and capable of alerting the consumer when alteration of the properties is taking place. Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large. Overall, with our work we take the first step along a promising path and demonstrate that printed polymer electronics is a potential enabler of such an appealing future technology.","[2.0, 1.0, 3.0, 1.0, 1.0]",Computer_Science,train,1.6,tweets,969617141002657793
10.1073/pnas.1810287115,Computer_Science_tweet_125,"This methodology creates more accurate estimators, alongside measured Health Information Systems (#HIS) errors, to improve tracking the public’s health. ⁦@username⁩  ","By combining the probability survey and HIS data, a hybrid prevalence estimate can be generated that can be used to validate and/or moderate HIS administrative estimates of coverage.","This methodology creates more accurate estimators, alongside measured Health Information Systems (#HIS) errors, to improve tracking the public’s health. ⁦@username⁩  ","Although these are a major advance, they are not well suited to drive operational policy decisions and detect gaps in service coverage. By combining the probability survey and HIS data, a hybrid prevalence estimate can be generated that can be used to validate and/or moderate HIS administrative estimates of coverage. The denominator of each targeted age group differs for the two campaigns; the VAS denominator is estimated from the 1993 census data and extrapolated with a population growth rate of 2.8% (13), whereas the polio campaign denominator uses the number of children reached during the previous polio campaign.","[4.0, 2.0, 4.0, 2.0]",Computer_Science,train,3.0,tweets,1070603695933534208
10.1126/science.aao3466,Computer_Science_tweet_126,"Our latest paper is just out in Science,  where we digitize a multistep organic synthesis of a pharmaceutical that can be done in 3D printed reactionware.","Here, any location with access to a sufficiently diverse market of chemical precursors and suitable cartridge fabrication facilities could be used to produce chemical products, which could previously be achieved only in a fully equipped synthesis laboratory with highly trained staff.","Our latest paper is just out in Science,  where we digitize a multistep organic synthesis of a pharmaceutical that can be done in 3D printed reactionware.","The distribution model for fine and specialty chemicals, such as the APIs implied by this approach, would lead to a decentralizing of logistical approaches to chemical manufacture. Here, any location with access to a sufficiently diverse market of chemical precursors and suitable cartridge fabrication facilities could be used to produce chemical products, which could previously be achieved only in a fully equipped synthesis laboratory with highly trained staff. This approach not only holds promise for eventually delivering on-demand personalized medicines manufactured at, or near, the point of use, but also has short-term potential applications in the synthesis of APIs that are currently out of production.","[4.0, 2.0, 4.0, 2.0]",Computer_Science,train,3.0,tweets,954069375581122560
10.1126/scirobotics.aat4051,Computer_Science_tweet_127,"Light-induced actuators that are self-contained and compact can be used as artificial muscles for microrobotics because their actuation can be induced wirelessly, which reduces the complexity of the device or system.... ","In addition, through an independent mechanism of a volume-changing electrochemical redox reaction, the shape of the fabricated actuator can be varied, which is of great importance for outdoor applications in which thin-film actuators in general can be sensitive under the ambient conditions.","Light-induced actuators that are self-contained and compact can be used as artificial muscles for microrobotics because their actuation can be induced wirelessly, which reduces the complexity of the device or system.... ","The high intrinsic actuating stress and response rate of the material system are comparable to mammalian skeletal muscles. In addition, through an independent mechanism of a volume-changing electrochemical redox reaction, the shape of the fabricated actuator can be varied, which is of great importance for outdoor applications in which thin-film actuators in general can be sensitive under the ambient conditions. The Vis light-induced actuation property of Ni(OH) 2 -NiOOH makes it an important addition to the known group of light-induced artificial muscles that are mainly functional under UV and NIR light, which is more harmful than Vis light.","[3.0, 2.0, 2.0, 2.0, 5.0]",Computer_Science,train,2.8,tweets,1001890723980029952
10.1098/rspa.2014.0182,Computer_Science_tweet_128,Extra-special trumpet time! When does a physical object compute ? Is the universe a (quantum) computer? Find out! ,"The two directions of the representation relation, modelling from physical to abstract, and instantiation from abstract to physical, lie at the heart of our questions around when a physical system computes.",Extra-special trumpet time! When does a physical object compute ? Is the universe a (quantum) computer? Find out! ,"While these two directions of representation are not absolutely disjoint, the exasperation sometimes expressed by experimentalists towards the unrealistic demands of theorists has its roots in the asymmetries of the representation relation between physical and abstract entities. The two directions of the representation relation, modelling from physical to abstract, and instantiation from abstract to physical, lie at the heart of our questions around when a physical system computes. This is an important point: the representation relation is theory-dependent.","[2.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.0,tweets,385025867455287297
10.1002/asi.23005,Computer_Science_tweet_129,Elite journals are publishing a decreasing proportion of top-cited papers. Via @username  (paywall),The quality of papers and competence of researchers should be evaluated independently of the journal in which the work appeared for two reasons.,Elite journals are publishing a decreasing proportion of top-cited papers. Via @username  (paywall),"Finally, advancement, recruitment and grant-evaluation committees, administrators and other evaluators should heed these results. The quality of papers and competence of researchers should be evaluated independently of the journal in which the work appeared for two reasons. Second, even if this journal hierarchy were valid, the hierarchy is not fixed.","[1.0, 1.0, 3.0, 3.0]",Computer_Science,train,2.0,tweets,404580851306201089
10.1007/s10055-018-0346-3,Computer_Science_tweet_13,"Research proves that Virtual Palaces in VR actually helps in remembering stuff better 

 via @username 

#VirtualReality #VR #education",The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.,"Research proves that Virtual Palaces in VR actually helps in remembering stuff better 

 via @username 

#VirtualReality #VR #education",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall. It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace.,"[3.0, 5.0, 5.0, 4.0]",Computer_Science,train,4.25,tweets,1156514842964107265
10.1038/s41598-018-31632-x,Computer_Science_tweet_130,"An iphoneX application to measure blood pressure using oscillometry
 ",Such ubiquitous BP monitoring may improve hypertension awareness and control rates and thereby help reduce the incidence of cardiovascular disease and mortality.,"An iphoneX application to measure blood pressure using oscillometry
 ","In summary, this proof-of-concept study surprisingly indicates that cuff-less and calibration-free BP monitoring may be feasible with many existing and forthcoming smartphones by leveraging sensors built-in for other purposes. Such ubiquitous BP monitoring may improve hypertension awareness and control rates and thereby help reduce the incidence of cardiovascular disease and mortality. After excluding two outlier data points, each set of 20 data points appeared to be well fit by a line.","[3.0, 5.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.4,tweets,1036618579691626497
10.1287/mnsc.2014.1966,Computer_Science_tweet_132,When is it more productive for success to be treated as a failure? @username  ,"In our model actors primarily follow standard Bayesian updating, but place inordinately more weight on success/failure than other available information about future success.",When is it more productive for success to be treated as a failure? @username  ,"We also provide a simple theoretical model of outcome bias, which produces behavior consistent with our empirical findings. In our model actors primarily follow standard Bayesian updating, but place inordinately more weight on success/failure than other available information about future success. Additionally, this requires panel data on the strategy and its consequences for multiple periods.","[2.0, 4.0, 4.0, 1.0]",Computer_Science,train,2.0,tweets,493811125352681472
10.1145/2661229.2661257,Computer_Science_tweet_133,"Invisible 3D haptic shapes in air. Naise!!
#artandscience ",This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices.,"Invisible 3D haptic shapes in air. Naise!!
#artandscience ","This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices. The user perceives a discernible haptic shape when the corresponding acoustic interference pattern is generated above a precisely controlled two-dimensional phased array of ultrasound transducers. This method is also possible with magnetic levitation, removing the need for the articulated arm .","[2.0, 3.0, 4.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,540296942623162368
10.1111/tops.12078,Computer_Science_tweet_134,The myth of cognitive decline. This has certainly received a lot of press in the last 24 hrs.  (free access for now),"Once the cost of processing this extra information is controlled for in studies of human performance, findings that are usually taken to suggest declining cognitive capacities can be seen instead to support little more than the unsurprising idea that choosing between or recalling items becomes more difficult as their numbers increase.",The myth of cognitive decline. This has certainly received a lot of press in the last 24 hrs.  (free access for now),"Given that the models run (and can be rerun) on computers, the possibility that any differences in their performance are due to aging hardware can be eliminated; instead, their patterns of performance reflect the information-processing costs that must inevitably be incurred as knowledge is acquired. Once the cost of processing this extra information is controlled for in studies of human performance, findings that are usually taken to suggest declining cognitive capacities can be seen instead to support little more than the unsurprising idea that choosing between or recalling items becomes more difficult as their numbers increase. We suggest that the answer to this question lies in the way that psychometric tests neglect learning and its relationship to the statistical patterns that characterize human experience.","[5.0, 4.0, 4.0, 2.0, 2.0]",Computer_Science,train,4.0,tweets,425539046585020417
10.1126/scirobotics.aat7544,Computer_Science_tweet_135,"""Our results also showed improvements of children’s joint attention in the absence of the robot""  Was I wrong?  Well, over the 1 month study period at least...",These games provide opportunities for the child not only to understand that the caregiver or the robot has a different perspective but also to practice turn-taking and verbal communication.,"""Our results also showed improvements of children’s joint attention in the absence of the robot""  Was I wrong?  Well, over the 1 month study period at least...","To succeed in this game, the child needs to understand the social situations and emotional states of the characters. These games provide opportunities for the child not only to understand that the caregiver or the robot has a different perspective but also to practice turn-taking and verbal communication. Substantial effort was placed into making the system robust and easy to use.","[3.0, 1.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.0,tweets,1032399748798377986
10.1145/2872427.2883081,Computer_Science_tweet_136,I like this: how to spot early on if an online argument is worth having  (could have been useful in the past...),"However, it is consistent that successful arguments are less similar to the original post in content words.",I like this: how to spot early on if an online argument is worth having  (could have been useful in the past...),"If we instead use truncation to (artificially) control for reply length, persuasive arguments present lower similarity in all metrics, suggesting that effects might differ over local parts of the texts. However, it is consistent that successful arguments are less similar to the original post in content words. These features attempt to capture linguistic style and its connections to persuasion success.","[4.0, 3.0, 3.0, 2.0]",Computer_Science,train,3.0,tweets,696730486270509056
10.1016/j.ijgfs.2011.11.002,Computer_Science_tweet_137,"@username @username Once you get into long cook times you are adding enzymatic breakdown and protein denaturization to the game.

Some say that greater than 4 hours and tender cuts (beef) turn mushy I disagree. Max time depends on what kind of protein. Do not 8hr chicken.

","When cooking tender meats, it's the fast changes that are the most important because the slow changes are mainly used to increase tenderness.","@username @username Once you get into long cook times you are adding enzymatic breakdown and protein denaturization to the game.

Some say that greater than 4 hours and tender cuts (beef) turn mushy I disagree. Max time depends on what kind of protein. Do not 8hr chicken.

","While cooking times are longer than traditional cooking methods, the meat comes up to temperature surprisingly quickly because the thermal conductivity of water is 23 times greater than that of air. When cooking tender meats, it's the fast changes that are the most important because the slow changes are mainly used to increase tenderness. Thus, for tender meat you just need to get the center up to temperature and, if pasteurizing, hold it there until any pathogens have been reduced to a safe level.","[4.0, 1.0, 4.0, 3.0]",Computer_Science,train,4.0,tweets,1088811514490949632
10.1016/j.robot.2015.01.003,Computer_Science_tweet_138,"A very interesting study appeared recently in Arxiv on spatial notions for robotic systems. According to the researchers, the robots should develop its own perceptual notions, analyzing its sensorimotor experiences and identifying meaningful patterns. #AI

","Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands.","A very interesting study appeared recently in Arxiv on spatial notions for robotic systems. According to the researchers, the robots should develop its own perceptual notions, analyzing its sensorimotor experiences and identifying meaningful patterns. #AI

","In particular, knowledge of a metric space enables odometry and SLAM . Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands. Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent.","[1.0, 4.0, 4.0, 4.0]",Computer_Science,train,4.0,tweets,1052746968915734529
10.1177/1080569913501862,Computer_Science_tweet_14,Should you use your mobile phone/smart phone during business meetings? ,"In formal meetings, professionals in the West were least accepting of mobile phone use during meetings.",Should you use your mobile phone/smart phone during business meetings? ,"Prior to getting the results, we suspected there might be some variation by region. In formal meetings, professionals in the West were least accepting of mobile phone use during meetings. In informal meetings, professionals in the Southwest were least accepting of mobile phone use.","[2.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.0,tweets,818216240338665472
10.1007/s10055-018-0346-3,Computer_Science_tweet_140,"Fascinating research shows how #VR ""memory palaces"" help with recall of info - would be interesting to conduct similar study for #MixedReality #embodied #SpatialAwareness ",The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms.,"Fascinating research shows how #VR ""memory palaces"" help with recall of info - would be interesting to conduct similar study for #MixedReality #embodied #SpatialAwareness ","However, participants were susceptible to disorientation if their starting-out views were different between their training and testing. The authors concluded that training in the virtual and real-world environments likely used similar cognitive mechanisms. They found that users in a HMD were better able to keep track of the objects by rotating their heads as compared to using a joystick.","[4.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.5,tweets,1155462875957399552
10.1126/science.aaf2654,Computer_Science_tweet_141,Autonomous Vehicles Need Experimental Ethics: Are We Ready for Utilitarian Cars? ,"If anything, they imagined future AVs as being less utilitarian than they should be.",Autonomous Vehicles Need Experimental Ethics: Are We Ready for Utilitarian Cars? ,"Thus, participants were not worried about AVs being too utilitarian, as often portrayed in science-fiction. If anything, they imagined future AVs as being less utilitarian than they should be. Participants did not think that AVs should sacrifice their passenger when only one pedestrian could be saved (with an average approval rate of 23%), but their moral approval increased with the number of lives that could be saved (p < 0.001) up to approval rates consistent with the 76% observed in Study 1 (Fig.","[3.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,657608912229695488
10.1007/s10055-018-0346-3,Computer_Science_tweet_143,Great reason why broader non-gaming VR use is inevitable once we have typing and reading comfortably in headsets solved. ,"If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall.",Great reason why broader non-gaming VR use is inevitable once we have typing and reading comfortably in headsets solved. ,"Given the results of our user study, we believe that virtual memory palaces offer us a fascinating insight into how we may be able to organize and structure large information spaces and navigate them in ways that assist in superior recall. If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.","[3.0, 2.0, 3.0, 2.0, 4.0]",Computer_Science,train,2.8,tweets,1155117835825426433
10.1007/s10055-018-0346-3,Computer_Science_tweet_144,"University of Maryland researchers conducted one of the first in-depth analyses on whether people recall information better through #VR, as opposed to desktop computers. ",Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory.,"University of Maryland researchers conducted one of the first in-depth analyses on whether people recall information better through #VR, as opposed to desktop computers. ","If memory recall could be enhanced through immersively experiencing the environment in which the information was learned, it would suggest that virtual environments could serve as a valuable tool for various facets of retrospective cognizance, including retention and recall. Our study provides a tantalizing glimpse into what may lie ahead in virtual-environment-based tools to enhance human memory. The next steps will be to identify and characterize what elements of virtual memory palaces are most effective in eliciting a superior information recall.","[4.0, 3.0, 4.0, 5.0, 2.0]",Computer_Science,train,3.6,tweets,1008772051677696000
10.1287/orsc.2014.0951,Computer_Science_tweet_145,Winning an Oscar increases divorce rate for men but not women  HT @username,"Second, rather than stratifying the data using marriage number, we also used a continuous variable to control for marriage number, which has the advantage of controlling for occurrence dependence (we could not control for both marriage and divorce number because divorce number equals marriage number minus one) .",Winning an Oscar increases divorce rate for men but not women  HT @username,"Using a depreciation constant of 0.25, for example, the Oscar effect in a two-year-old marriage would be depreciated with a factor of 0.61 (exp(-0.25 x 2)), whereas the effect would be depreciated with a factor of 0.37 (exp(-0.25 x 4) in a four-year-old marriage. Second, rather than stratifying the data using marriage number, we also used a continuous variable to control for marriage number, which has the advantage of controlling for occurrence dependence (we could not control for both marriage and divorce number because divorce number equals marriage number minus one) . The results are robust regardless of approach, thus suggesting that we report the results using the more informative second approach.","[2.0, 1.0, 4.0, 2.0]",Computer_Science,train,2.25,tweets,568548946332631040
10.1098/rspb.2019.0646,Computer_Science_tweet_146,"A review of camouflage by Hughes et al. in Proc B suggests a range of camouflage strategies, with many open questions on how they are optimised in the wild or how they interact with crypsis or defensive markings.  ","Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment.","A review of camouflage by Hughes et al. in Proc B suggests a range of camouflage strategies, with many open questions on how they are optimised in the wild or how they interact with crypsis or defensive markings.  ","Optimal countershading appears to be strongly illumination dependent [61] and having suboptimal countershading seems to be almost as bad as having no countershading at all, at least in a study with highly different illumination conditions . Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment. While the study of imperfect camouflage is valuable in its own right, it also has a number of important implications for other areas of biology.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1134339998973595649
10.1126/scirobotics.aan4582,Computer_Science_tweet_147,.@username @username software on Mars #CuriosityRover selects rock targets w/ 93% accuracy compared to 24% w/out  ,The system is capable of finding targets in images from either MSL's NavCams or the ChemCam RMI.,.@username @username software on Mars #CuriosityRover selects rock targets w/ 93% accuracy compared to 24% w/out  ,"AEGIS has been adapted for the MSL mission to allow autonomous target selection and data acquisition for ChemCam. The system is capable of finding targets in images from either MSL's NavCams or the ChemCam RMI. In the NavCam case, the operation is analogous to the use on the MER mission, for finding targets in unknown terrain after a drive into a new locale.","[3.0, 1.0, 3.0, 4.0]",Computer_Science,train,2.75,tweets,877587886350192640
10.1111/j.1083-6101.2009.01474.x,Computer_Science_tweet_148,Social media increasing feelings of connectedness? Interesting read on #sm &amp; college students' social capital ,"Using the same approach of entering multiplicative terms in the models for civic and political participation, only one interaction achieved statistical significance: The relationship between intensity of Facebook Groups use and political participation was weaker for white respondents than for minority respondents (β = −.23, p < .05).",Social media increasing feelings of connectedness? Interesting read on #sm &amp; college students' social capital ,"No other interactive term in the regression of political participation was statistically significant. Using the same approach of entering multiplicative terms in the models for civic and political participation, only one interaction achieved statistical significance: The relationship between intensity of Facebook Groups use and political participation was weaker for white respondents than for minority respondents (β = −.23, p < .05). Our results provide consistent evidence that these positive associations exist.","[3.0, 1.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.8,tweets,387666679175843841
10.1073/pnas.1812296116,Computer_Science_tweet_149,These origami-inspired field test devices detected malaria in 98% of infected participants in a case study in Uganda. Read more:  ,"Importantly, this sensitivity is above the minimal performance target set out by WHO and FIND .",These origami-inspired field test devices detected malaria in 98% of infected participants in a case study in Uganda. Read more:  ,"Taking into account the tests for Plasmodium pan and P. falciparum, the paper-based microfluidic device had a sensitivity of >98% and a coincidence rate of 97% (95% CI, 91.99 to 100%), compared with the test results generated by real-time PCR (Table 1) . Importantly, this sensitivity is above the minimal performance target set out by WHO and FIND . Our method was also more sensitive than the microscopy detection method used (which detected infection in 86% of the tested cases).","[1.0, 2.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.6,tweets,1097965339793678337
10.1287/mksc.2013.0837,Computer_Science_tweet_15,A study found that changing the faces presented in ads resulted in more effective persuasive ads.  ,Ad agencies should also pay attention to possible heterogeneity in the preferences of the target audience and use different faces to target different customer segments.,A study found that changing the faces presented in ads resulted in more effective persuasive ads.  ,"The substantial effect of different faces on advertising effectiveness indicates that ad agencies should be careful when selecting faces to appear in print advertisements. Ad agencies should also pay attention to possible heterogeneity in the preferences of the target audience and use different faces to target different customer segments. In addition, the methods used in the present study provide a new approach for professionals interested in conducting a quantitative study to assist in the screening and selection of print media spokespersons.","[5.0, 2.0, 4.0, 2.0, 2.0]",Computer_Science,train,3.0,tweets,505749602977316864
10.1038/nature18933,Computer_Science_tweet_151,Mapping the human brain - using ML to make an accurate parcellation of cortex  ,"The bilateral symmetry of functional organization is striking, in that nearly all areas have qualitatively very similar hues in the left and right hemispheres.",Mapping the human brain - using ML to make an accurate parcellation of cortex  ,"The remaining regions form a complex mosaic, with some intermixing of lighter (task-positive) and darker (task-negative) areas along with many lighter or darker pastel hues suggestive of 'cognitive' areas that may be preferentially associated with one or another sensory modality. The bilateral symmetry of functional organization is striking, in that nearly all areas have qualitatively very similar hues in the left and right hemispheres. However, interesting colour asymmetries occur in a few areas, especially language-related areas 55b, PSL, SFL, and 44 and their right hemisphere homologues, which also have asymmetric task-fMRI functional profiles (see Supplementary Neuroanatomical Results 8, 21 and 22) .","[1.0, 4.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.6,tweets,755812681521692672
10.1186/1754-1611-3-11,Computer_Science_tweet_152,"""A bacterial computer capable of finding a Hamiltonian path in a three node directed graph.""
","DNA edges flanked by hixC sites can be reshuffled by Hin recombinase, creating random orderings and orientations of edges of the graph.","""A bacterial computer capable of finding a Hamiltonian path in a three node directed graph.""
","The design of our bacterial computer benefited from a series of abstractions of DNA sequence into the edges and nodes of a Hamiltonian path. DNA edges flanked by hixC sites can be reshuffled by Hin recombinase, creating random orderings and orientations of edges of the graph. Hin-mediated recombination of the 14 DNA edges could produce 1.42 × 10 15 possible configurations.","[2.0, 3.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.8,tweets,599200235001286656
10.1038/s41598-018-30656-7,Computer_Science_tweet_153,"This study showed how individual ants and their colonies choose a nest using two models developed for information processing in vertebrates. Interestingly, (unlike humans) colonies make faster decisions when two options are available than only one. ",The fact that the less preferred option experiences more severe cross-censoring (only the extreme of its left tail sees action) leads to one additional prediction in the SCM: the predicted shortening of latency for binary respect to single-option choices is more pronounced for the worse (less preferred) option than for the better (preferred) option.,"This study showed how individual ants and their colonies choose a nest using two models developed for information processing in vertebrates. Interestingly, (unlike humans) colonies make faster decisions when two options are available than only one. ","This interaction cross-censors the right tails of both latency distributions, and thus when an option is encountered and chosen in the presence of an alternative, observed mean latencies are shorter than those for the option when presented alone 28 . The fact that the less preferred option experiences more severe cross-censoring (only the extreme of its left tail sees action) leads to one additional prediction in the SCM: the predicted shortening of latency for binary respect to single-option choices is more pronounced for the worse (less preferred) option than for the better (preferred) option. As noted above, the ToW model predicts a shift in the opposite direction (i.e.","[2.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.75,tweets,1034115759549685761
10.1111/jcc4.12162,Computer_Science_tweet_154,Research showing positive emotional well-being results of Facebook use.  ,"Respondents noted the importance of seemingly trivial interactions, such as sharing jokes or videos: ""I post funny cat videos to her wall and she writes on my wall counting down the days until we're in the same town and get to see each other.""",Research showing positive emotional well-being results of Facebook use.  ,"Certainly much of the composed communication on Facebook may still be trivial but generate perceived support. Respondents noted the importance of seemingly trivial interactions, such as sharing jokes or videos: ""I post funny cat videos to her wall and she writes on my wall counting down the days until we're in the same town and get to see each other."" ""His comments are hilarious, we get to trade jabs online.""","[4.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.75,tweets,783388621948588033
10.1145/3219819.3219896,Computer_Science_tweet_155,"DEADLY TOXIC LEAD PIPES in #Flint, Michigan

The Search for DEADLY TOXIC LEAD PIPES in #Flint, Michigan that have caused the PERMANENT BRAIN DAMAGE of HUNDREDS of THOUSANDS of American families.

✨

@username | #DataScience, #MachineLearning, #Healthcare ",IWAL more effectively optimizes HVI hit rate.,"DEADLY TOXIC LEAD PIPES in #Flint, Michigan

The Search for DEADLY TOXIC LEAD PIPES in #Flint, Michigan that have caused the PERMANENT BRAIN DAMAGE of HUNDREDS of THOUSANDS of American families.

✨

@username | #DataScience, #MachineLearning, #Healthcare ",egreedy(0) tends to over-inspect whereas egreedy (1) is too conservative. IWAL more effectively optimizes HVI hit rate. activities different than Flint FAST Start.,"[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1013025610132803586
10.1038/nn.4354,Computer_Science_tweet_156,"@username Yep, the connectivity of inferior parietal involved in phonology with the vOT involved in orthography is critical for the development of reading skill. Love this study too:  #dyslexia #orthography #phonology","Furthermore, the ability to predict later brain function from an anatomical scan that can be performed even in a sleeping infant Figure 5 Left-lateralized regions that are preferentially connected with the VWFA versus lFFA or lPFS at age 5.","@username Yep, the connectivity of inferior parietal involved in phonology with the vOT involved in orthography is critical for the development of reading skill. Love this study too:  #dyslexia #orthography #phonology","In sum, our longitudinal, cross-lagged study supports the hypothesis that early connectivity instructs the functional development of the VWFA, a cortical region that underlies the uniquely human ability to read. Furthermore, the ability to predict later brain function from an anatomical scan that can be performed even in a sleeping infant Figure 5 Left-lateralized regions that are preferentially connected with the VWFA versus lFFA or lPFS at age 5. Connectivity (of the region that will become the VWFA) to these regions was already elevated (compared to nearby cortex) at age 5, even when no evidence of functional differentiation existed in the VWFA at that age.","[1.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.0,tweets,988904717873971202
10.1073/pnas.1407887111,Computer_Science_tweet_157,"Players in multiplayer social dilemma
games can increase control &amp; strategic options by joining
forces with others. ",We call such ZD strategies fair.,"Players in multiplayer social dilemma
games can increase control &amp; strategic options by joining
forces with others. ","5, such a player enforces the payoff relation π i = π −i , such that i's payoff matches the average payoff of the other group members. We call such ZD strategies fair. As shown in Fig.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,534913174064361472
10.1515/popets-2015-0007,Computer_Science_tweet_158, experiments on gender #discrimination through automated #ads,The top two URL+title pairs for the female group was for a generic job posting service and for an auto dealer., experiments on gender #discrimination through automated #ads,Google showed the ads 1852 times to the male group but just 318 times to the female group. The top two URL+title pairs for the female group was for a generic job posting service and for an auto dealer. The found discrimination in this experiment was predominately from a pair of job-related ads for the same service making the finding highly sensitive to changes in the serving of these ads.,"[4.0, 2.0, 2.0, 2.0]",Computer_Science,train,2.5,tweets,620150224904941570
10.1126/sciadv.aat2731,Computer_Science_tweet_159," Sampling molecular conformations and dynamics in a multi-user virtual reality framework. (arXiv:1801.02884v1 [physics.ed-ph]), by Michael O Connor, Helen M. Deeks, Edward Dawn, Oussama Metatla, Anne Roudaut, Matthew Sutton, Becca Rose Glowacki, Rebecca S…","However, closer inspection of the helicene time distributions suggest that VR does afford some advantage: the median time required to change molecular screw-sense in VR is 30-40% less than the median time required on a touchscreen."," Sampling molecular conformations and dynamics in a multi-user virtual reality framework. (arXiv:1801.02884v1 [physics.ed-ph]), by Michael O Connor, Helen M. Deeks, Edward Dawn, Oussama Metatla, Anne Roudaut, Matthew Sutton, Becca Rose Glowacki, Rebecca S…","Essentially, the 2d limitations of the mouse and touchscreen constrain the user to carrying out a motion which is well suited to inducing changes in molecular screw-sense. However, closer inspection of the helicene time distributions suggest that VR does afford some advantage: the median time required to change molecular screw-sense in VR is 30-40% less than the median time required on a touchscreen. Significantly, every task considered in Figs 2 and 3 shows a median VR time which (i) is always faster than the mean, and (ii) lies outside the standard error limits.","[4.0, 3.0, 4.0, 1.0]",Computer_Science,train,2.0,tweets,950902908517801984
10.1098/rspb.2014.1195,Computer_Science_tweet_16,"Balance between ""white"" and ""black"" lies appears to determine fragmentation of social networks and thus society ","The results of our study suggest that not all lies are bad or necessarily socially destructive; in fact, it seems that some lies may even enhance the cohesion of the society as a whole and help to create links with other people.","Balance between ""white"" and ""black"" lies appears to determine fragmentation of social networks and thus society ","Although we are taught from an early age that lying is unacceptable, children nonetheless learn to lie wisely instead of eschewing it completely. The results of our study suggest that not all lies are bad or necessarily socially destructive; in fact, it seems that some lies may even enhance the cohesion of the society as a whole and help to create links with other people. In effect, some kinds of lies might actually be essential to the smooth running of society, and if so, the balance between pro-and antisocial lies may be crucial in shaping social structure.","[3.0, 5.0, 1.0, 1.0]",Computer_Science,train,3.0,tweets,475486137478172673
10.1073/pnas.1322355111,Computer_Science_tweet_160,Happily disgusted &amp; sadly angry: @username paper says there are 21 compound facial expressions cf 6 recognised before ,"For when one suffers anything, one becomes as if one has the kind of expression: when one is angry, the sign of the same class is angry.",Happily disgusted &amp; sadly angry: @username paper says there are 21 compound facial expressions cf 6 recognised before ,"We show that these differences are sufficient to distinguish between the 21 defined categories. For when one suffers anything, one becomes as if one has the kind of expression: when one is angry, the sign of the same class is angry. (1) A s nicely illustrated in the quote above, for centuries it has been known that many emotional states are broadcasted to the world through facial expressions of emotion.","[2.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.25,tweets,450834603276648448
10.1162/jocn_a_00450,Computer_Science_tweet_161,@username #Blind participants detected blue light and it influenced their #brain activity: #cognitivescience ,No classical visual responses were detected in any tests.,@username #Blind participants detected blue light and it influenced their #brain activity: #cognitivescience ,"Visual acuity tests previously performed in Boston indicated no light perception in either eye of the three participants. No classical visual responses were detected in any tests. Finally, questionnaire scores indicated that Participants 2 and 3 reported, respectively, relatively poor sleep quality and high propensity to fall asleep during the day (Table 1 ).","[3.0, 2.0, 1.0, 3.0]",Computer_Science,train,2.25,tweets,396206168193761281
10.1007/978-3-319-67256-4_3,Computer_Science_tweet_162,Digital Flynn Effect: The complexity of social media posts has been constantly increasing.  ,VKs support team confirmed to us that the data downloaded via their API may be used for research purposes.,Digital Flynn Effect: The complexity of social media posts has been constantly increasing.  ,"In particular, it is possible to download user profiles from certain educational institutions and within selected age ranges. VKs support team confirmed to us that the data downloaded via their API may be used for research purposes. The relationship between time of site adoption and complexity growth in Fig.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,888726643568758784
10.1287/msom.2016.0587,Computer_Science_tweet_163,Open Access UCL Research: The time-money trade-off for entrepreneurs: when to hire the first employee? ,Our work builds on several streams of literature.,Open Access UCL Research: The time-money trade-off for entrepreneurs: when to hire the first employee? ,"Although mistiming hiring is costly in both entrepreneurial and established firms, the effect may be more severe in entrepreneurial firms because it stunts growth in addition to deferring future profits. Our work builds on several streams of literature. Taking an operations management perspective we derive a simple guideline for how an employee should be valued based on the level of relief s/he provides to the entrepreneur's time constraint.","[1.0, 1.0, 2.0]",Computer_Science,train,1.3333333333333333,tweets,903606848506535936
10.1177/1461444814543163,Computer_Science_tweet_164,"What do online flags mean &amp; what are alternatives? @username &amp; @username ""unpack the working of the flag"": ","In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand.","What do online flags mean &amp; what are alternatives? @username &amp; @username ""unpack the working of the flag"": ","The flag is merely the first step in a process of content regulation, a process that most sites hope either disappears completely beneath the smooth operation of the site, or when it must appear, to present itself as a rational and fair policing mechanism. In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand. The opacity of the process means that the site is not obligated to honor the flags it does receive, and that any decision to remove content can be legitimized as being in response to complaints from the community.","[2.0, 3.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.6,tweets,489656584943828992
10.1136/amiajnl-2013-002033,Computer_Science_tweet_166,"Predicting changes in hypertension control using EHRs from a chronic disease mngmt program,Apr.15 #dataanalytics #iot
","BP varies throughout the course of a 24-h day (it is highest in the evening and lowest in the morning) with additional intrinsic, random variation of between 5 and 15 mm Hg depending on patient characteristics, acute illness, medications, and methods of measurement.","Predicting changes in hypertension control using EHRs from a chronic disease mngmt program,Apr.15 #dataanalytics #iot
","We show how both types of transition can be utilized as target labels to build predictive models. BP varies throughout the course of a 24-h day (it is highest in the evening and lowest in the morning) with additional intrinsic, random variation of between 5 and 15 mm Hg depending on patient characteristics, acute illness, medications, and methods of measurement. 3.","[2.0, 2.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.8,tweets,576037281506684928
10.1073/pnas.1411728112,Computer_Science_tweet_167,Morning! Today we have two interesting drafts in arXiv. 2nd law of thermodynamics in quantum systems. ,"This paradigm is equivalent to ones in which we allow interaction Hamiltonians rather than unitaries, or where we allow for a Hamiltonian which changes with time, provided that all ancillas are carefully accounted for [ .",Morning! Today we have two interesting drafts in arXiv. 2nd law of thermodynamics in quantum systems. ,"Operations which pump energy into or from the system can be incorporated into the paradigm by including the source of energy as an ancillary system. This paradigm is equivalent to ones in which we allow interaction Hamiltonians rather than unitaries, or where we allow for a Hamiltonian which changes with time, provided that all ancillas are carefully accounted for [ . Considering such resources are crucial, since the experimenter who is trying to extract work or otherwise manipulate a system, should be allowed as much ingenuity as possible.","[2.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.5,tweets,337852912447401984
10.1038/nature13404,Computer_Science_tweet_168,Algorithm allows accurate design of multi-component protein complexes for self-assembling nanomaterials @username ,"In the structures with resolutions that permit detailed analysis of side-chain configurations (T33-15 and two independent crystal forms of T33-21), 87 of 113 side chains at the designed interfaces adopt the predicted conformations (Supplementary Tables 5 and  6 ).",Algorithm allows accurate design of multi-component protein complexes for self-assembling nanomaterials @username ,"In all cases, the structures reveal that the inter-building-block interfaces were designed with high accuracy: comparing a pair of chains from each structure to the computationally designed model yields backbone root mean square Table 1 ). In the structures with resolutions that permit detailed analysis of side-chain configurations (T33-15 and two independent crystal forms of T33-21), 87 of 113 side chains at the designed interfaces adopt the predicted conformations (Supplementary Tables 5 and  6 ). over all 24 subunits in each material range from 1.0 to 2.6 Å (Fig.","[1.0, 2.0, 2.0, 1.0]",Computer_Science,train,1.5,tweets,471954600900440065
10.1093/database/bat080,Computer_Science_tweet_169,"#ISB2014 simultaneously @ AMIA @username values curators, e.g.""manual curation of lit is possible and useful"" ","In total, 9 489 curated articles yielded 38 083 phenotype interactions, of which 31 903 (84%) were for chemical-phenotype, 6% were for gene-phenotype and 10% were for complex chemical-gene-phenotype interactions ( Figure 4B ).","#ISB2014 simultaneously @ AMIA @username values curators, e.g.""manual curation of lit is possible and useful"" ","From the drug-phenotype corpus, 36 742 phenotype interactions were curated, and an additional 1 341 interactions came from 401 articles of the drug-disease corpus that were incidentally curated for phenotype information during the transition period between projects (Table 2 ). In total, 9 489 curated articles yielded 38 083 phenotype interactions, of which 31 903 (84%) were for chemical-phenotype, 6% were for gene-phenotype and 10% were for complex chemical-gene-phenotype interactions ( Figure 4B ). Apoptosis was the most frequently curated phenotype, followed by blood pressure, cell proliferation, oxidative stress and cell cycle ( Figure 2D ).","[1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.25,tweets,454272117396094976
10.1038/s41586-019-1157-8,Computer_Science_tweet_17,"An optical version of a brain-inspired neurosynaptic system, using wavelength division multiplexing techniques, is presented that is capable of supervised and unsupervised learning. #deeplearning  ","The neurosynaptic system described so far provides the basic structure needed for supervised learning tasks, where the weights of the inputs are set by an external supervisor.","An optical version of a brain-inspired neurosynaptic system, using wavelength division multiplexing techniques, is presented that is capable of supervised and unsupervised learning. #deeplearning  ","1c , serves as a building block in layered photonic networks (described below) suited to the scalable implementation of neurosynaptic systems. The neurosynaptic system described so far provides the basic structure needed for supervised learning tasks, where the weights of the inputs are set by an external supervisor. Probe pulses sent to the waveguide lying below the neuronal ring resonator either couple to it or generate an output spike depending, as described previously, on whether the neuronal PCM cell is in the crystalline or amorphous state.","[3.0, 4.0, 3.0, 3.0, 5.0]",Computer_Science,train,3.6,tweets,1126405796693196800
10.1073/pnas.1710231115,Computer_Science_tweet_170,"This, simply, is the future of ecology. So excited to see this come out in PNAS. Congratulations @username @username @username ","Ecological forecasting would benefit from cyberinfrastructure for the automation, public dissemination, and archiving of ecological forecasts, which will allow community advances in two important ways.","This, simply, is the future of ecology. So excited to see this come out in PNAS. Congratulations @username @username @username ","It can happen immediately using existing data, often with only modest reframing of the questions asked and the approaches taken. Ecological forecasting would benefit from cyberinfrastructure for the automation, public dissemination, and archiving of ecological forecasts, which will allow community advances in two important ways. First, by looking across different types of forecasts, we can take a comparative approach to understanding what affects predictability in ecology.","[1.0, 1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.2,tweets,958403974696235008
10.1038/s41598-017-03412-6,Computer_Science_tweet_171,"Time dimension: 3D printed thermally responsive shape memory polymers create actively deployable tensegrities. 
",Such a design leads to successful deployment (Movie S3).,"Time dimension: 3D printed thermally responsive shape memory polymers create actively deployable tensegrities. 
","In this way, the tensegrity deployment becomes more deterministic, while the structure can still be stored in a compact state that occupies much less space than its deployed configuration. Such a design leads to successful deployment (Movie S3). Our active tensegrity can be used to form 3D structures with surfaces that can serve as a platform to host functional devices.","[2.0, 4.0, 4.0, 2.0]",Computer_Science,train,3.0,tweets,877094026385793024
10.1186/s13040-014-0033-1,Computer_Science_tweet_172,"#Microarray enriched #gene #rank  #biodatamining (followed by #InTextoResearch, #Wallonia, #Belgium)",Also we show the names of 10 positively and two the most negatively correlated genes.,"#Microarray enriched #gene #rank  #biodatamining (followed by #InTextoResearch, #Wallonia, #Belgium)","The width of the bar is proportional to the gene's correlation coefficient with remaining genes. Also we show the names of 10 positively and two the most negatively correlated genes. As follows from this plot, less correlated genes are at the BPESC1 GSTT1 NLRP2 TCHH PON3 TYRP1 CRYBB2 TP53 TECTA CDH19 PCDHGA9 KCNG2 TDRD1 DDX43 HTR1F RPH3AL NPR3 THSD7A CXORF1 KL DAZL HOXD9 GUCY1B2 LDHAL6B MIA 25 most connected genes HCN2 GRIN1 ELA2 POU3F1 RBMXL2 HNF4A APC2 UTF1 SCRT1 PRDM12 SOX10 CACNA1I PRTN3 CDK5R2 HRH3 SEMA6B SOX1 CSF3 CHAT WNT1 ALX4 OLIG2 ADRB1 ACCN4 bottom and more correlated genes are at the top (the yellow curve represents the density of the squared correlation distribution).","[1.0, 1.0, 4.0, 2.0, 1.0]",Computer_Science,train,1.8,tweets,563595822269743104
10.1016/j.neuroimage.2018.03.045,Computer_Science_tweet_173,"@username @username Yes!! Also, know people working w/ GANs for high resolution PET images at low dose like this work ➡️ ",This order was necessarily fixed because we need to acquire clinical PET scans first and then the experimental scans.,"@username @username Yes!! Also, know people working w/ GANs for high resolution PET images at low dose like this work ➡️ ","The average time post-injection was 36 min (from 32 to 41 min). This order was necessarily fixed because we need to acquire clinical PET scans first and then the experimental scans. The order, however, creates some implications.","[2.0, 3.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.4,tweets,1150475983184642048
10.1126/sciadv.aap9815,Computer_Science_tweet_174,"Here is the online dating study being reported in several papers. Some interesting results
 ","The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones.","Here is the online dating study being reported in several papers. Some interesting results
 ","The lower set of curves in the top panels shows the probability of receiving a reply to an initial message. The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones. The differences are stark: men are more than twice as likely to receive a reply from women less desirable than themselves than from more desirable ones, and for messages sent to more desirable women the reply rate never rises above 21%.","[2.0, 3.0, 4.0, 2.0]",Computer_Science,train,2.75,tweets,1027459155437801472
10.1016/j.trc.2019.05.025,Computer_Science_tweet_175,Look who is talking now? The automated vehicles! Check our recent publication on building trust in AVs via explanations in Transportation Research Part C. @username @username @username   ,Preference for AV is another important outcome.,Look who is talking now? The automated vehicles! Check our recent publication on building trust in AVs via explanations in Transportation Research Part C. @username @username @username   ,"Thus, anxiety should be an outcome used to assess the effectiveness of AV explanations. Preference for AV is another important outcome. If this were true, it would be important to capture preference along with the measures of trust and anxiety.","[1.0, 3.0, 4.0, 1.0, 4.0]",Computer_Science,train,1.0,tweets,1133428279715610627
10.1038/nature13457,Computer_Science_tweet_176,A protocol to verify nuclear warheads without revealing sensitive information to the inspector @username ,They achieve the paradoxical goal of allowing one to prove that a statement is true without revealing why it is true.,A protocol to verify nuclear warheads without revealing sensitive information to the inspector @username ,"Such agreements would require new verification approaches, including inspections of individual nuclear warheads in storage and warheads entering the dismantlement queue. They achieve the paradoxical goal of allowing one to prove that a statement is true without revealing why it is true. Such proofs are extremely useful for many digital applications, including privacy-preserving data mining, electronic voting and online auctions .","[1.0, 2.0, 1.0, 2.0]",Computer_Science,train,1.5,tweets,482180268217098240
10.1038/nature20607,Computer_Science_tweet_177,"Engineered protein ""nanocages"" release vesicles! ","By contrast, cells that expressed the control I3-01-Myc construct released very little VSV-G and no BlaM-Vpr, indicating that these two proteins were probably released via EPN incorporation.","Engineered protein ""nanocages"" release vesicles! ","EPN-01*, BlaM-Vpr and VSV-G were efficiently released together from 293T producer cells as designed (Fig. By contrast, cells that expressed the control I3-01-Myc construct released very little VSV-G and no BlaM-Vpr, indicating that these two proteins were probably released via EPN incorporation. Consistent with this interpretation, the fraction of EPN-01* assemblies with visible surface spikes increased fourfold upon VSV-G pseudotyping (Fig.","[3.0, 1.0, 1.0]",Computer_Science,train,1.6666666666666667,tweets,804037672037711879
10.1098/rsos.150152,Computer_Science_tweet_179,"Playing iterated vocal charades leads to iconic vocal communication systems:
","The exception was that the distance between the intensity of the vocalization and the target word was a reliable predictor of accuracy, such that smaller distances lead to greater accuracy (z = −2.66, p < 0.","Playing iterated vocal charades leads to iconic vocal communication systems:
","With one exception, the same pattern of results was also found for the absolute distance between vocalization and word with respect to each variable separately: iconic distance remained highly reliable (z's < −4.02, p's < 0.001), and shorter variable distances did not predict greater accuracy (z's > 0.59). The exception was that the distance between the intensity of the vocalization and the target word was a reliable predictor of accuracy, such that smaller distances lead to greater accuracy (z = −2.66, p < 0. Across all meanings, there was a moderate negative correlation between the iconic distance to that meaning and its probability of selection, regardless of its correctness (r = −0.30, p < 0.001), and a weaker negative correlation between selection probability and median distance (r = −0.18, p < 0.001).","[2.0, 5.0, 3.0, 3.0, 3.0]",Computer_Science,train,3.2,tweets,629588998772654080
10.1136/jamia.2009.001750,Computer_Science_tweet_18,"Per a study on @username website, 20% of duplicate tests were not clinically indicated. ",Duplicate testing occurred in 27/85 (32%) patients and was categorized as 'not clinically indicated' in 17/ 85 (20%) patients (table 2).,"Per a study on @username website, 20% of duplicate tests were not clinically indicated. ",A total of 833 ACHD patients were hospitalized under the guidance of the BACH service during the 2-year study time period. Duplicate testing occurred in 27/85 (32%) patients and was categorized as 'not clinically indicated' in 17/ 85 (20%) patients (table 2). Fifty percent of the patients with duplicative testing had more than one test duplicated.,"[4.0, 5.0, 3.0, 4.0, 4.0]",Computer_Science,train,4.0,tweets,1054402772286746626
10.1016/j.ipm.2016.06.009,Computer_Science_tweet_180,A very interesting practical approach to social media analysis. @username @username @username ,This is a particular concern given that this type of tweet is a likely future application of the program.,A very interesting practical approach to social media analysis. @username @username @username ,Its performance was weakest for all metrics on the set of tweets matching stress and relaxation terms. This is a particular concern given that this type of tweet is a likely future application of the program. The low performance on this sub-corpus reflects TensiStrength being likely to classify all tweets as having at least moderate levels of either stress or relaxation and so there would be relatively few easy classifications of texts with no matching terms.,"[3.0, 1.0, 3.0, 2.0, 4.0]",Computer_Science,train,2.6,tweets,802090576430698496
10.1098/rsif.2013.1211,Computer_Science_tweet_182,"@username Is twitter making us stupid? Social networks and unreflective copying bias 
","What counts as evidence for process contagion is a significant interaction between question and topology, showing that the increase in performance in the network group is greater than the increase in performance in the Baseline group.","@username Is twitter making us stupid? Social networks and unreflective copying bias 
","Processing contagion should improve performance from one question to the next, in addition to improving performance from one trial to the next. What counts as evidence for process contagion is a significant interaction between question and topology, showing that the increase in performance in the network group is greater than the increase in performance in the Baseline group. We detected no such significant interaction for any topology, all z , 1.05, all p .","[2.0, 1.0, 2.0]",Computer_Science,train,1.6666666666666667,tweets,431448343370162176
10.1162/jocn_a_00785,Computer_Science_tweet_183,MIT Press Journals - Journal of Cognitive Neuroscience - Full Text ,"Finally, individuals who showed stronger dorsomedial PFC activity at baseline in a separate task were generally more efficient when adopting the intentional stance and reported having greater social skills.",MIT Press Journals - Journal of Cognitive Neuroscience - Full Text ,"Second, moment-to-moment variation in default activity during fixation in the dorsomedial PFC was related to the ease with which participants applied an intentionalbut not nonintentional-stance to a social stimulus presented moments later. Finally, individuals who showed stronger dorsomedial PFC activity at baseline in a separate task were generally more efficient when adopting the intentional stance and reported having greater social skills. These results identify a biological basis for the human tendency to adopt the intentional stance.","[1.0, 3.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.6,tweets,613200851725848576
10.1038/nature17941,Computer_Science_tweet_184,In @username V1 columns have OFF-dominated central region flanked by ON-subfields  ,This distinct arrangement of ON and OFF inputs enables continuity in the mapping of both orientation and visual space and the generation of a columnar map of absolute spatial phase.,In @username V1 columns have OFF-dominated central region flanked by ON-subfields  ,"As a result, cortical columns exhibit an invariant aggregate receptive field structure: an OFF-dominated central region flanked by ON-dominated subfields. This distinct arrangement of ON and OFF inputs enables continuity in the mapping of both orientation and visual space and the generation of a columnar map of absolute spatial phase. 1a, b ), A large fraction (42%) of the layer 2/3 neurons that showed statistically significant receptive fields in response to this stimulus (see Methods) had spatially offset ON and OFF subfields, consistent with the organization of simple cells that has been described in other species.","[2.0, 3.0, 3.0, 1.0, 3.0]",Computer_Science,train,2.4,tweets,725390614066520066
10.1016/j.neuron.2018.02.031,Computer_Science_tweet_185,"The Joglekar et al. model simulates the non-linear ignition of parietal and prefrontal areas (and relevant sensory areas) during the perception of weak stimuli of variable strength -- which we propose as a neural correlate of conscious perception.
 ","Improved propagation is accompanied by a small change in gamma power across areas ( Figure 4B ), stemming from the stronger lateral inhibition associated with improved GBA.","The Joglekar et al. model simulates the non-linear ignition of parietal and prefrontal areas (and relevant sensory areas) during the perception of weak stimuli of variable strength -- which we propose as a neural correlate of conscious perception.
 ","Increasing GBA improves signal transmission in this model as well ( Figure 4B ), suggesting that our mechanism is also valid for models equipped with more detailed laminar-specific projection patterns (Mejias et al., 2016) . Improved propagation is accompanied by a small change in gamma power across areas ( Figure 4B ), stemming from the stronger lateral inhibition associated with improved GBA. The moderate gamma power is in good agreement with experimental observations, which show the presence of a weakly coherent gamma rhythm during cortical interactions and its importance in local and long-distance interactions (Kopell et al., 2000; .","[3.0, 1.0, 1.0]",Computer_Science,train,1.6666666666666667,tweets,993432810676539392
10.1073/pnas.1800708115,Computer_Science_tweet_187,A new universal of language processing: nouns slow down speech! Read our new PNAS paper at ,These conditions on noun use appear to outweigh potential advantages stemming from differences in internal complexity between nouns and verbs.,A new universal of language processing: nouns slow down speech! Read our new PNAS paper at ,"We attribute this slowdown effect to the increased amount of planning that nouns require compared with verbs. These conditions on noun use appear to outweigh potential advantages stemming from differences in internal complexity between nouns and verbs. Our findings suggest that, beneath the staggering diversity of grammatical structures and cultural settings, there are robust universals of language processing that are intimately tied to how speakers manage referential information when they communicate with one another.","[4.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.75,tweets,996266522107629568
10.1073/pnas.1813476116,Computer_Science_tweet_189,"Congratulations to talented students @username @_mlechha and a hat tip to productive, proficient peer review.  Local, linear models; fine-grained clustered states and near-critical dynamics in brains and behavior. @username ","We note that the success of the local linear basis in revealing interpretable worm behavior results in part from the ability to capture oscillations and the interactions between different posture modes, both common components of movement behavior.","Congratulations to talented students @username @_mlechha and a hat tip to productive, proficient peer review.  Local, linear models; fine-grained clustered states and near-critical dynamics in brains and behavior. @username ","This can be useful for developing a master repertoire of behaviors ( as well as looking for differences between nematode species or studying perturbations to behavior ( ( . We note that the success of the local linear basis in revealing interpretable worm behavior results in part from the ability to capture oscillations and the interactions between different posture modes, both common components of movement behavior. The eigenvalues of the posture dynamics reflect variability and hint at the presence of flexible control.","[3.0, 3.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.6,tweets,1086318208490061824
10.1126/science.aar3106,Computer_Science_tweet_19,A deep result on shallow circuits: Bravyi-Gosset-König prove constant-depth q circuits outperform classical ones ,We prove that constant-depth quantum circuits are more powerful than their classical counterparts.,A deep result on shallow circuits: Bravyi-Gosset-König prove constant-depth q circuits outperform classical ones ,"We prove that constant-depth quantum circuits are more powerful than their classical counterparts. We prove that any classical probabilistic circuit composed of bounded fan-in gates that solves the 2D Hidden Linear Function problem with high probability must have depth logarithmic in n. In contrast, we show that this problem can be solved with certainty by a constant-depth quantum circuit composed of one-and two-qubit gates acting locally on a two-dimensional grid. Many problems of practical importance such as Monte Carlo simulation, computing the rank, the determinant, and the inverse of a matrix lend themselves naturally to parallelization .","[5.0, 5.0, 4.0, 4.0, 5.0]",Computer_Science,train,4.6,tweets,849250229060816897
10.1145/3205455.3205541,Computer_Science_tweet_190,"Researchers have used genetic algorithms to explore how evolutionary algorithms can design robot legs adapted to walk on specific surfaces. The results of this proof of concept may suggest a new way of designing control systems for walking robots.

","Despite this, mean times for a full experiment set (10 repeats in an environment) are 7 hours, 2.7 days, and 9.4 days respectively.","Researchers have used genetic algorithms to explore how evolutionary algorithms can design robot legs adapted to walk on specific surfaces. The results of this proof of concept may suggest a new way of designing control systems for walking robots.

","Importantly, native support is provided to distribute the simulation effort in parallel across high-performance computing nodes; (i) each experimental repeat is run in parallel (ii) all evaluations in a generation are conducted in parallel, and (iii) each individual particle-based evaluation distributes across a compute node. Despite this, mean times for a full experiment set (10 repeats in an environment) are 7 hours, 2.7 days, and 9.4 days respectively. Hexapod bodies do not directly interact with the environment, allowing us to optimise legs only.","[2.0, 1.0, 2.0]",Computer_Science,train,1.6666666666666667,tweets,1054568014966915072
10.1145/2998181.2998219,Computer_Science_tweet_191,"Integrating Quantified Self Sensing and Social Media

#HelterSkelterChallenge",Our ability to estimate risk of failure can enable timely and tailored deployment of gamification approaches.,"Integrating Quantified Self Sensing and Social Media

#HelterSkelterChallenge","Gamification is also possible wherein daily diet compliance success/failure can translate to confidence boosting concrete metrics like rewards, points or badges . Our ability to estimate risk of failure can enable timely and tailored deployment of gamification approaches. Additionally, mechanisms could be created on social media platforms to provide socially supportive interventions to individuals at risk of diet compliance failure (e.g., those expressing high NA or high cognitive impairment in their Twitter posts).","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,907949683661619201
10.1145/2872427.2883081,Computer_Science_tweet_192,Fact-checkers! Debunkers! Check out this Cornell study on changing people's minds on social media  h/t @username,"Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts.",Fact-checkers! Debunkers! Check out this Cornell study on changing people's minds on social media  h/t @username,"There are many possible extensions to our approach for representing arguments. Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts. Finally, beyond mechanisms behind persuasion, it is a vital research problem to understand how community norms encourage such a well-behaved platform so that useful rules, moderation practices, or even automated tools can be deployed in future community building.","[2.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.0,tweets,697800694162722816
10.1073/pnas.98.2.676,Computer_Science_tweet_194,study showing areas of brain that are activated while resting (precursor paper to concept of default mode network) ,"The primary issue this paper will address is whether these unexplained decreases merely arise from unrecognized increases (i.e., activation in the jargon of functional brain imaging) present only in the ''control state.''",study showing areas of brain that are activated while resting (precursor paper to concept of default mode network) ,"This consistency with which certain areas of the brain participate in these decreases made us wonder whether there might be an organized mode of brain function that is present as a baseline or default state and is suspended during specific goal-directed behaviors. The primary issue this paper will address is whether these unexplained decreases merely arise from unrecognized increases (i.e., activation in the jargon of functional brain imaging) present only in the ''control state.'' Thus, on this argument, any control state, no matter how carefully it is selected, is just another task state with its own unique areas of activation.","[1.0, 2.0, 2.0, 2.0]",Computer_Science,train,1.75,tweets,587492981130702848
10.1073/pnas.1411728112,Computer_Science_tweet_195,The second laws of #quantum thermodynamics  @username #physics,"In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state.",The second laws of #quantum thermodynamics  @username #physics,"We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is. In one regime one can cause an apparent violation of the usual second law, through a process of embezzling work from a large system which remains arbitrarily close to its original state. These second laws are not only relevant for small systems, but also apply to individual macroscopic systems interacting via long-range interactions, which only satisfy the ordinary second law on average.","[3.0, 4.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.6,tweets,861515836279934977
10.1145/2872427.2883081,Computer_Science_tweet_196,New paper on the dynamics of r/changemyview ,"In response to the same original post, there are many possible ways to change someone's view.",New paper on the dynamics of r/changemyview ,"So, while the challenger's opening argument should be important, statements made later in the rooted path-unit could be more important. In response to the same original post, there are many possible ways to change someone's view. Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic.","[4.0, 3.0, 1.0, 3.0]",Computer_Science,train,2.75,tweets,695321170875392000
10.1073/pnas.1419704112,Computer_Science_tweet_197,The truth about language change that was so SHOCKING it had to be suppressed! Released from embargo @username ,"Our analyses revealed two significant patterns in the data: languages that had larger speaker populations tended to have higher rates of gain of new words in basic vocabulary than their smaller sister languages, and smaller populations tended to have higher rates of word loss from basic vocabulary (Table 1 and Fig.",The truth about language change that was so SHOCKING it had to be suppressed! Released from embargo @username ,"The models varied in (i) whether the data were phylogenetically structured or not, (ii) whether new populations rapidly achieved a stable population size upon colonizing a new area, or underwent a more protracted period of growth, (iii) whether new languages formed by an allopatric process, where a parent population underwent fission to produce two daughter populations, or by a peripatric process, where the parent population gave rise to a daughter population by a process of colonization, and (iv) whether or not new languages experienced a founder effect, losing a number of words when a new population became established (Methods). Our analyses revealed two significant patterns in the data: languages that had larger speaker populations tended to have higher rates of gain of new words in basic vocabulary than their smaller sister languages, and smaller populations tended to have higher rates of word loss from basic vocabulary (Table 1 and Fig. Variation in population size explained about 10-20% of the variation in word gains and losses (Table 1) .","[3.0, 1.0, 4.0, 3.0, 3.0]",Computer_Science,train,2.8,tweets,562375053421989889
10.1073/pnas.98.2.676,Computer_Science_tweet_198,"Existence of organized, baseline default mode of brain function is suspended during specific goal-directed behaviors.
",Deviations from this equilibrium produced by transient changes in this modal level of neural activity manifest themselves as changes in the OEF and provide us with the signals underlying modern functional brain imaging with fMRI.,"Existence of organized, baseline default mode of brain function is suspended during specific goal-directed behaviors.
",The uniformity of the OEF in the absence of specific goal-directed activities supports our belief that an established equilibrium exists between the local metabolic requirements necessary to sustain a long-term modal level of neural activity and the level of blood flow in a particular region. Deviations from this equilibrium produced by transient changes in this modal level of neural activity manifest themselves as changes in the OEF and provide us with the signals underlying modern functional brain imaging with fMRI. Note that these are all increases in the OEF signifying areas of deactivation in the baseline state of resting but awake with eyes closed.,"[2.0, 3.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.2,tweets,399315446073393152
10.1038/s41598-018-29429-z,Computer_Science_tweet_2,"""Metabolic cost of walking explained by combination of 4 costs—swing &amp; torso dynamics, COM velocity redirection, ground clearance, and body weight support. Overall energetic cost depends on how these separable components tradeoff and manifest under different walking conditions."" ","Our results suggest that the metabolic cost of walking can largely be explained by the linear combination of four costs-swing and torso dynamics, center of mass velocity redirection, ground clearance, and body weight support.","""Metabolic cost of walking explained by combination of 4 costs—swing &amp; torso dynamics, COM velocity redirection, ground clearance, and body weight support. Overall energetic cost depends on how these separable components tradeoff and manifest under different walking conditions."" ","added mass), and reduced gravity conditions, without the need for parameter tuning to design new gait trajectories. Our results suggest that the metabolic cost of walking can largely be explained by the linear combination of four costs-swing and torso dynamics, center of mass velocity redirection, ground clearance, and body weight support. The overall energetic cost is a tradeoff among these separable components, shaped by how they manifest under different walking conditions.","[4.0, 5.0, 5.0, 5.0]",Computer_Science,train,4.75,tweets,1022846405168250880
10.1186/s12918-019-0687-x,Computer_Science_tweet_20,Effects of unpaired 1 gene overexpression on the lifespan of #Drosophila melanogaster. Open access in BMC Systems Biology: ,The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of the JAK/STAT target genes domeless and Socs36E.,Effects of unpaired 1 gene overexpression on the lifespan of #Drosophila melanogaster. Open access in BMC Systems Biology: ,"Thus, conditional overexpression of the upd1 gene encoding a JAK/STAT signaling ligand results in alteration of the Drosophila lifespan depending on the tissue specificity of overexpression. The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of the JAK/STAT target genes domeless and Socs36E. As the JAK/STAT pathway is evolutionarily conserved it may be possible to discover compounds that fit the criteria of geroprotector .","[2.0, 2.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.4,tweets,1115929975704698882
10.1016/j.ijgfs.2011.11.002,Computer_Science_tweet_201,Have a sous vide cooker? Here's a little weekend reading to understand the science behind the methods. Tons of info on food safety and the chemical processes initiated by the heat. ,At lower temperatures (50 found that tough cuts of beef (from animals 0-4 years old) were the most tender when cooked to between 55,Have a sous vide cooker? Here's a little weekend reading to understand the science behind the methods. Tons of info on food safety and the chemical processes initiated by the heat. ,At 80 found that these effects occur within about 12-24 hours with tenderness increasing only slightly when cooked for 50 to 100 hours. At lower temperatures (50 found that tough cuts of beef (from animals 0-4 years old) were the most tender when cooked to between 55 • C/131 • F and 60,"[4.0, 1.0, 1.0, 2.0, 2.0]",Computer_Science,train,2.0,tweets,1157470188310188032
10.1088/1741-2552/aabc9b,Computer_Science_tweet_202,This free article from the Journal of Neural Engineering describes the first demonstration of adaptive DBS (deep brain stimulation) in Parkinson's disease using a fully implanted device and neural sensing.  ,"The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded.",This free article from the Journal of Neural Engineering describes the first demonstration of adaptive DBS (deep brain stimulation) in Parkinson's disease using a fully implanted device and neural sensing.  ,"While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches. The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded. Although this approach has shown promise 1,2 , the STN LFP is a low amplitude signal that is strongly affected by stimulation artifact when stimulation is delivered on adjacent contacts.","[4.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.5,tweets,1022376201900490752
10.1145/2872427.2883081,Computer_Science_tweet_203,#NotesOnStrategy #Research | Persuasion Strategies in Good-faith Online Discussions |  HT @username #Startups,"Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic.",#NotesOnStrategy #Research | Persuasion Strategies in Good-faith Online Discussions |  HT @username #Startups,"In response to the same original post, there are many possible ways to change someone's view. Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic. This leads to a balanced binary prediction task: which of the two lexically similar rooted path-units is the successful one?","[3.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.5,tweets,714943001726992385
10.1016/j.robot.2015.01.003,Computer_Science_tweet_204,"Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) 

The design of robotic systems is largely dictated by our purely human intuition about how we perceive the world. This intuition has been proven incorrect w…","Even if sensations s depend on the environment, the sets M s are thus environmentindependent.","Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) 

The design of robotic systems is largely dictated by our purely human intuition about how we perceive the world. This intuition has been proven incorrect w…","Those particular cases aside, every set M s corresponds to a certain input s but also to a certain position of the agent in space. Even if sensations s depend on the environment, the sets M s are thus environmentindependent. All the possible sets M i have a specific structure that can be captured to build an internal representation of the external agent's configuration.","[2.0, 1.0, 2.0, 1.0, 3.0]",Computer_Science,train,1.8,tweets,1048019732329390080
10.1073/pnas.1419704112,Computer_Science_tweet_205,"Larger populations=higher rates of gain of new words | Smaller pops=higher rates of word loss  Kudos, @username","We have selected only pairs of languages where the relationships are well established and there is no evidence of replacement or blending of populations, avoiding populations with complicated settlement histories.","Larger populations=higher rates of gain of new words | Smaller pops=higher rates of word loss  Kudos, @username","Similarly we have carefully selected sister pairs with known relationships, whereas a whole-tree approach would require us to make assumptions about the more distant relationships between the ancestral lineages that gave rise to these contemporary populations. We have selected only pairs of languages where the relationships are well established and there is no evidence of replacement or blending of populations, avoiding populations with complicated settlement histories. Thus, the sister-pairs approach represents a conservative approach to the data that minimizes the assumptions that we must make about the history of the languages and the mechanisms of population and language change.","[1.0, 1.0, 4.0, 4.0, 2.0]",Computer_Science,train,1.0,tweets,562428968968527872
10.1073/pnas.98.2.676,Computer_Science_tweet_206,For a better understanding of the brain activity &gt; very interesting... ,"These decreases suggest the existence of an organized, baseline default mode of brain function that is suspended during specific goaldirected behaviors.",For a better understanding of the brain activity &gt; very interesting... ,"Defining the baseline state of an area in this manner attaches meaning to a group of areas that consistently exhibit decreases from this baseline, during a wide variety of goal-directed behaviors monitored with positron-emission tomography and functional MRI. These decreases suggest the existence of an organized, baseline default mode of brain function that is suspended during specific goaldirected behaviors. 1 and 2).","[3.0, 2.0, 2.0]",Computer_Science,train,2.333333333333333,tweets,417321377306513408
10.1016/j.ijgfs.2011.11.002,Computer_Science_tweet_207,Took awhile for me to undo all I knew re:cooking. @username Did it. ,"Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90",Took awhile for me to undo all I knew re:cooking. @username Did it. ,"). Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90 • C/195","[3.0, 1.0, 2.0, 4.0]",Computer_Science,train,2.5,tweets,814098629090770944
10.1145/2872427.2883081,Computer_Science_tweet_208,@username Might be interested in this study which used Reddit to find what made effective online arguments. ,"Similar patterns occur in root reply and full path: in number of common words and OP fraction, persuasive arguments have larger values because they tend to be longer, as will be shown in §4.2.2; in reply fraction and Jaccard, which are normalized by reply length, persuasive arguments are more dissimilar from the original post in content words but more similar in stopwords.",@username Might be interested in this study which used Reddit to find what made effective online arguments. ,"The features based on interplay are all significant to a certain degree. Similar patterns occur in root reply and full path: in number of common words and OP fraction, persuasive arguments have larger values because they tend to be longer, as will be shown in §4.2.2; in reply fraction and Jaccard, which are normalized by reply length, persuasive arguments are more dissimilar from the original post in content words but more similar in stopwords. Keeping in mind that the pairs we compare are chosen to be similar to each other, our analysis indicates that, under this constraint, persuasive arguments use a more different wording from the original post in content, while at the same time matching them more on stopwords.","[4.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.0,tweets,695445941784940544
10.1016/j.robot.2015.01.003,Computer_Science_tweet_210,"Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG])

The design of robo","Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow.","Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG])

The design of robo","Having a robot explore its environment for an extended period of time may thus be an inevitable cost to be paid for the autonomous emergence of such perceptual notions. Finally, the results highlight the fact that the proposed approach relies entirely on the properties of the raw sensorimotor flow. We thus believe that any perceptive knowledge should be discovered and grounded in sensorimotor experience.","[3.0, 2.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.6,tweets,1048015292427714562
10.1016/j.ijgfs.2011.11.002,Computer_Science_tweet_211,Everything You Wanted to Know About Sous Vide Cooking But Were Afraid to Ask ,Starchy vegetables can be cooked at the slightly lower temperature of 80,Everything You Wanted to Know About Sous Vide Cooking But Were Afraid to Ask ,• C/122 Starchy vegetables can be cooked at the slightly lower temperature of 80 • C/175,"[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,tweets,950020675481239552
10.1145/2872427.2883081,Computer_Science_tweet_212,A very interesting paper about how to change people's mind in online arguments:  ht @username,"The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle.",A very interesting paper about how to change people's mind in online arguments:  ht @username,"But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length. The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle. These differences are indicative of the functions that the two forms of utterances serve: a CMV rule is that original posts should not be ""like a persuasive essay"".","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,695817906395820032
10.1126/science.aaf2654,Computer_Science_tweet_214,[1510.03346] Autonomous Vehicles Need Experimental Ethics: Are We Ready for Utilitarian Cars? ,"Regression analyses (see Supplementary online materials) showed that enthusiasm for self-driving cars was consistently greater for younger, male participants.",[1510.03346] Autonomous Vehicles Need Experimental Ethics: Are We Ready for Utilitarian Cars? ,"A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far. Regression analyses (see Supplementary online materials) showed that enthusiasm for self-driving cars was consistently greater for younger, male participants. Accordingly, all subsequent analyses included age and sex as covariates.","[1.0, 1.0, 2.0, 3.0, 3.0]",Computer_Science,train,2.0,tweets,657395703598071808
10.1126/science.aaf2654,Computer_Science_tweet_215,Self-driving trolley problems! ,"Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.",Self-driving trolley problems! ,"For example, our scenarios did not feature any uncertainty about decision outcomes, but a collective discussion about moral algorithms will have to tackle the concepts of expected risk, expected value, and blame assignment. Such liability considerations will need to accompany existing discussions of regulation [21] , and we hope that psychological studies inspired by our own will be able to inform this discussion. Our datadriven approach highlights how the field of experimental ethics can give us key insights into the moral, cultural and legal standards that people expect from autonomous driving participants did not ex-press a comparable preference for buying utilitarian AVs, especially when they thought of family members riding in the car, and (c and d) they disapproved of regulations enforcing utilitarian algorithms for AVs, and indicated that they would be less likely to purchase an AV under such a regulation.","[1.0, 1.0, 2.0]",Computer_Science,train,1.3333333333333333,tweets,708492434355781632
10.1007/s10055-018-0346-3,Computer_Science_tweet_216,Been saying 👇for several years! With 4K screen now standard it is only going to get better 😊YES! @username @username @username @username @username @username @username @username @username @username @username  ,"Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall.",Been saying 👇for several years! With 4K screen now standard it is only going to get better 😊YES! @username @username @username @username @username @username @username @username @username @username @username  ,"It will be valuable to study how the addition of translation impacts information recall in a virtual memory palace. Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall. Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1155187314504716288
10.1007/s10055-018-0346-3,Computer_Science_tweet_217,"As exposed during my ""#VR &amp;philosophy, is VR a radically novel tool for thinking?"" evening lecture for @username 
  #WebVR also has a role to play for research. As the medium become popular large scale &amp; replication are easier. #MTurk studies can go deeper. ",Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored.,"As exposed during my ""#VR &amp;philosophy, is VR a radically novel tool for thinking?"" evening lecture for @username 
  #WebVR also has a role to play for research. As the medium become popular large scale &amp; replication are easier. #MTurk studies can go deeper. ",The technique of memory palaces provides a natural spatial mnemonic to assist in recall. Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored. Virtual environments that mirror the scene of the crime could provide superior assistance in recall by placing the victim back into such an environment.,"[3.0, 2.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.0,tweets,1155167046843453443
10.1007/s10055-018-0346-3,Computer_Science_tweet_218,Thinking spaces are going to be an important part of XR. I wrote about it here  ,"This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ).",Thinking spaces are going to be an important part of XR. I wrote about it here  ,"Lastly, place cells in the hippocampus activate in specific spatial locations, independent of orientation, providing an internal representation of the environment . This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ). This study found that the users who used a graphics desktop environment as the basis for their method of loci performed better than those using a mental scene of their choice, and those who were not instructed on a memory strategy did not perform as well as those who were instructed to use the memory strategy.","[1.0, 4.0, 1.0]",Computer_Science,train,1.0,tweets,1155162179508809729
10.1007/s10055-018-0346-3,Computer_Science_tweet_219,"Any cognition science research articles on what could be the process for encoding memories of navigating through space, thus relying on iterative feedback, so efficient?

Reading ""The Science of Managing Our Digital Stuff""  wondering why memory palaces work ","The above studies show that compared to a purely mental mnemonic, a graphics desktop setup is better in assisting retention and recall.","Any cognition science research articles on what could be the process for encoding memories of navigating through space, thus relying on iterative feedback, so efficient?

Reading ""The Science of Managing Our Digital Stuff""  wondering why memory palaces work ","The study found that there was no significant difference between the users' ability to immediately recall the words after a 2-min break, but after one week there was a 25% difference in recall in favor of the 3D graphics desktop memory palace environment condition. The above studies show that compared to a purely mental mnemonic, a graphics desktop setup is better in assisting retention and recall. The study found that higher levels of immersion (in this case, field of view) were more effective in learning complex procedures that reference spatial locations.","[1.0, 3.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.0,tweets,1162059473181126656
10.1093/cybsec/tyy006,Computer_Science_tweet_22,"Categorising the harm done by cyber attacks - interesting paper identifies at least 57 separate ways organisations can be harmed (including work from @username) 

This matters so we’re all talking about the same thing.","To comment briefly on key findings in the 2017 report, the survey highlights that all UK businesses are potentially exposed to cyber-threats.","Categorising the harm done by cyber attacks - interesting paper identifies at least 57 separate ways organisations can be harmed (including work from @username) 

This matters so we’re all talking about the same thing.","The report presents statistics about how organizations operate in cyberspace and identifies common types of threat. To comment briefly on key findings in the 2017 report, the survey highlights that all UK businesses are potentially exposed to cyber-threats. They have identified that a sizeable proportion of businesses still lack security controls despite the fact that the vast majority of them have increased their cybersecurity budget.","[1.0, 2.0, 4.0, 3.0, 3.0]",Computer_Science,train,2.6,tweets,1055406603216846848
10.1007/s10055-018-0346-3,Computer_Science_tweet_220,VR significantly aids recall vs screen-based training - another one to add to the evidence pile:  #MedEd #virtualreality #vr ,"If the participants were in the same orientation that they had used during learning, they were able to navigate the environment just as well as those who were physically in the environment.",VR significantly aids recall vs screen-based training - another one to add to the evidence pile:  #MedEd #virtualreality #vr ,"However, when the building had two floors, relative view orientation during learning and testing mattered. If the participants were in the same orientation that they had used during learning, they were able to navigate the environment just as well as those who were physically in the environment. However, participants were susceptible to disorientation if their starting-out views were different between their training and testing.","[1.0, 2.0, 4.0, 3.0, 3.0]",Computer_Science,train,2.6,tweets,1164209804992274433
10.1098/rspb.2014.1370,Computer_Science_tweet_221,Science report: Orcas and other animals may speak with complexity   #Biological,"We found that the letter order in the English language is best modelled by a ZOMP, whereas previous work has indicated that an SOMP is a more appropriate model .",Science report: Orcas and other animals may speak with complexity   #Biological,"The results of our test for robustness show that, with the exception of the pilot whale data, wherever a clear best-fit model is indicated, the chosen model is consistent between larger sub-sample sizes, and we believe that this is an indication of reliability of our conclusions. We found that the letter order in the English language is best modelled by a ZOMP, whereas previous work has indicated that an SOMP is a more appropriate model . However, English is clearly neither a ZOMP nor an FOMP, and so the resemblance of a corpus of English letters to one or the other may be more dependent on the metric used to assess similarity, rather than the underlying stochastic processes.","[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,tweets,502234205409931264
10.1007/978-3-642-55220-5_1,Computer_Science_tweet_222,Gesundheit! MT @username: for weekend reading: A Heuristic Quasi-Polynomial Algorithm for Discrete Logarithm ,"However, in almost the whole range of applicability of the Function Field Sieve algorithm, our algorithm is asymptotically better than FFS.",Gesundheit! MT @username: for weekend reading: A Heuristic Quasi-Polynomial Algorithm for Discrete Logarithm ,"If the characteristic of the base field is not so small compared to the extension degree, the complexity of our algorithm does not keep its nice quasi-polynomial form. However, in almost the whole range of applicability of the Function Field Sieve algorithm, our algorithm is asymptotically better than FFS. The condition can then be rewritten as log q = O((log Q) α (log log Q) 1−α ) and therefore k = log Q/ log q = O((log Q/ log log Q) 1−α ).","[2.0, 4.0, 2.0, 1.0, 1.0]",Computer_Science,train,2.0,tweets,469503028588863488
10.1145/3230833.3232807,Computer_Science_tweet_224,"The rise of connectivity, digitalisation, and robotics, combined with the race for bringing artificial intelligence into every aspect of our daily life, is rapidly changing our society and shaping its future development. During this technological and soc…  ","Pepper offers to users a nice web page where some administrative tasks, such as factory reset and password change, can be easily performed.","The rise of connectivity, digitalisation, and robotics, combined with the race for bringing artificial intelligence into every aspect of our daily life, is rapidly changing our society and shaping its future development. During this technological and soc…  ","After a quick verification of the CPU model, we report that Pepper is prone both to Meltdown and Spectre attacks . Pepper offers to users a nice web page where some administrative tasks, such as factory reset and password change, can be easily performed. As soon as we opened the web page, we noticed that the communication is established over HTTP, rather than HTTPS.","[2.0, 2.0, 1.0, 3.0]",Computer_Science,train,2.0,tweets,994737498055172096
10.1126/scirobotics.aaw1977,Computer_Science_tweet_225,#Robotics: scientists created an autonomous robotic #catheter that can navigate through the blood-filled heart using algorithms and haptic vision. The device provides important benefits to clinicians and can be used for many minimally invasive procedures  ,"The Pearson's coefficient was equal to 0.97, which indicates a strong linear relationship.",#Robotics: scientists created an autonomous robotic #catheter that can navigate through the blood-filled heart using algorithms and haptic vision. The device provides important benefits to clinicians and can be used for many minimally invasive procedures  ,"7C) . The Pearson's coefficient was equal to 0.97, which indicates a strong linear relationship. 7C indicates that the contact duty cycle range of 0.35 to 0.45 that we used in most of our experiments corresponded to a maximum force of 1.25 to 2.3 N.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1121169746563665921
10.1177/0018720815587803,Computer_Science_tweet_227,&amp; then there's the #trustinautomation angle for operators of multiple #UAVs:  ,"However, these differences in performance did not manifest in the nongaming population.",&amp; then there's the #trustinautomation angle for operators of multiple #UAVs:  ,"Gamers in the negative-priming group understood the imperfections in the automation, reporting lower trust in the AS. However, these differences in performance did not manifest in the nongaming population. One potential reason is that gamers may have a higher propensity to overtrust automation.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,758041647527501825
10.1073/pnas.1613982114,Computer_Science_tweet_228,"Cool use of monocular/dichoptic paradigm to test how subcortical structures are involved in numerosity encoding

","Mauchly's test indicated that sphericity was violated [X 2 (9) = 23.6; P < 0.01], and therefore, the degrees of freedom were corrected in the linear model using Huynh-Feldt correction (« = 0.80).","Cool use of monocular/dichoptic paradigm to test how subcortical structures are involved in numerosity encoding

","Regarding task difficulty, the overall median accuracy and RT were 96.7% and 543.9 ms. Mauchly's test indicated that sphericity was violated [X 2 (9) = 23.6; P < 0.01], and therefore, the degrees of freedom were corrected in the linear model using Huynh-Feldt correction (« = 0.80). A repeatedmeasures ANOVA with ratio and ocularity (monocular/dichoptic) as within-subjects factors and IE as the dependent measure revealed a significant two-way interaction [F (3.2,80) = 2.73; P = 0.04].","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,843947914644750337
10.1038/s41528-018-0040-2,Computer_Science_tweet_229,"Woven light emitting textiles and sensors are no longer science fiction as a work by Elias (@username and @username,  @username ) shows in Nature Flexible Electronics  #graphene #textiles",SLG and FLG with different ranges of conductivity and transparency) to LEG.,"Woven light emitting textiles and sensors are no longer science fiction as a work by Elias (@username and @username,  @username ) shows in Nature Flexible Electronics  #graphene #textiles","Furthermore, by using different types of graphene we demonstrate that our devices can be produced in a more industrial manufacturing compatible way. SLG and FLG with different ranges of conductivity and transparency) to LEG. S4a ), confirming the presence of the different types of graphene on the surface of the PP textile fibres.","[1.0, 1.0, 5.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1044527556177874944
10.1038/s41586-018-0361-2,Computer_Science_tweet_230,"Yeah, bravo! ","The Higgs-boson discovery analyses firmly established its interactions with the electroweak-force-carrying particles, namely the photon, W boson and Z boson.","Yeah, bravo! ","The increase in sensitivity due to the use of machine learning was equivalent to collecting 50% more data. The Higgs-boson discovery analyses firmly established its interactions with the electroweak-force-carrying particles, namely the photon, W boson and Z boson. This means that the Higgs boson is expected to decay into heavier quarks and leptons more often than into their lighter cousins.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,1025052269576953856
10.3389/frobt.2016.00072,Computer_Science_tweet_231,"@username   
Can the human brain learn to interpret a virtual world delivered through direct brain stimulation and no other sensory inputs? #robotics #braincomputerinteraction
 ","As seen in Figure 10 , no significant correlation exists between maze index and the probability that an error occurred on a turn [Pearson r = 0.04, t(12) = 0.15, p = 0.88].","@username   
Can the human brain learn to interpret a virtual world delivered through direct brain stimulation and no other sensory inputs? #robotics #braincomputerinteraction
 ","Specifically, the probability of an error occurring on a turn should be higher in the later mazes than in the earlier ones. As seen in Figure 10 , no significant correlation exists between maze index and the probability that an error occurred on a turn [Pearson r = 0.04, t(12) = 0.15, p = 0.88]. Our results suggest that human subjects can learn to interpret the information delivered via non-invasive brain stimulation to solve a task in a virtual world.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,986578590920617985
10.1016/j.ijmedinf.2013.11.003,Computer_Science_tweet_232,Doctors - look up from your computer screen! ,"The study described in this paper focuses on gaze, but similar approaches can be used to understand the effects of other interactions that contribute to patient outcomes such as emotion.",Doctors - look up from your computer screen! ,"In these cases, to understand emotion, you would want to understand when the emotional state changes and the events that trigger the change, the events that influence the emotion are also the points that can lead to redesign or training. The study described in this paper focuses on gaze, but similar approaches can be used to understand the effects of other interactions that contribute to patient outcomes such as emotion. The results showed that doctor's gaze patterns are followed significantly by patient gaze patterns, for instance if doctor gazed at the patient, the patient gazed back at the doctor.","[2.0, 2.0, 2.0]",Computer_Science,train,2.0,tweets,433582657013022720
10.1038/s41598-019-39384-y,Computer_Science_tweet_233,"Should you take a protective action such as Drop, Cover, and Hold On every time you receive a ShakeAlert? Latest study says: yes, every time. Learn more:  @username @username @username @username @username ",This result holds for each of our four cities and the generic uniform random catalog.,"Should you take a protective action such as Drop, Cover, and Hold On every time you receive a ShakeAlert? Latest study says: yes, every time. Learn more:  @username @username @username @username @username ","The most common outcome the user experiences is the ""correct no alert"" case, reflecting myriad small or distant earthquakes that should not and do not produce significant ground motion at the user's location. This result holds for each of our four cities and the generic uniform random catalog. (Note that the deaggregated frequency of occurrence of this case is shown on log scale in Figs 4-6, S1-S2, because it is so plentiful.)","[2.0, 1.0, 1.0]",Computer_Science,train,1.3333333333333333,tweets,1098530537356984320
10.1038/s41560-018-0290-1,Computer_Science_tweet_234,Integrating economic valuation of storage technologies with key battery chemistry parameters towards more accurate representation of viability of storage - now in @username ,The congestion-relief application is similar to that of the energy time shift.,Integrating economic valuation of storage technologies with key battery chemistry parameters towards more accurate representation of viability of storage - now in @username ,"The time-shift application in the DAM works by charging the ESS when the forecasted price of energy is low, and then discharging the ESS when the forecasted price of energy is high . The congestion-relief application is similar to that of the energy time shift. The flexible ramping application accounts for the power fluctuations required to adjust to energy delivery over periods of the order of five minutes .","[2.0, 1.0, 2.0, 1.0, 2.0]",Computer_Science,train,1.6,tweets,1070653833293033473
10.1126/scirobotics.aar7555,Computer_Science_tweet_235,Artificial #snake skins by @username @username help immobile #robots crawl away:   ,"In this case, x a /L approaches ±0.5, and anchoring occurs at the tail during inflation/elongation and at the head during deflation/shortening, completely preventing backward sliding.",Artificial #snake skins by @username @username help immobile #robots crawl away:   ,"By balancing the frictional forces exerted by the substrate on the skin (while neglecting inertial forces due to the slow nature of the crawling motion), we show that (see the Supplementary Materials for details) indicates that, to maximize the distance traveled by the crawlers, the ratio m b /m f should be as large as possible. In this case, x a /L approaches ±0.5, and anchoring occurs at the tail during inflation/elongation and at the head during deflation/shortening, completely preventing backward sliding. Moreover, Eq.","[1.0, 3.0, 3.0, 2.0]",Computer_Science,train,2.25,tweets,966391870162132992
10.1287/mnsc.2014.2030,Computer_Science_tweet_236,Too embarrassed to order dessert from a human?  -- @username et al. found a similar effect: ,The qualitative results do not change in any specification.,Too embarrassed to order dessert from a human?  -- @username et al. found a similar effect: ,"Second, it might be possible to exploit the matched pairs to increase power addresses these concerns by using flexible specifications for the functional form of the time series and by aggregating the fixed e↵ects to the pair level. The qualitative results do not change in any specification. Figure 4 repeats the analysis in Column (1) at a finer level of temporal detail.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,603258906555592706
10.1186/s12911-016-0327-y,Computer_Science_tweet_237,"“I think everyone should be using social media in their practices."" Social media use by physicians:  
",It's not a lot of time.,"“I think everyone should be using social media in their practices."" Social media use by physicians:  
","One participant described: ""I would say, the nice thing about social media is that you can do it in between things. It's not a lot of time. While some physicians postulated that their posts on social media may increase clinic efficiency by decreasing unnecessary patient calls and visits, others believed that it decreased efficiency by distracting providers from direct patient care.","[1.0, 1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.4,tweets,755406928830984192
10.1126/science.aat4807,Computer_Science_tweet_238,"Catalyzing discovery of drug interactions by ""secret sharing"" and neural networks, coalescing proprietary sources to rev up biomedical research
 by @username's Hie,  @username, Berger @username #AI @username #Crypto #openscience ","The top prediction from both methods was an interaction between the estrogen receptor (ER) and droloxifene, which had reached phase 3 clinical trials as an ER modulator for advanced breast cancer (25) .","Catalyzing discovery of drug interactions by ""secret sharing"" and neural networks, coalescing proprietary sources to rev up biomedical research
 by @username's Hie,  @username, Berger @username #AI @username #Crypto #openscience ","It will be interesting to find out whether this interaction is confirmed by other studies. The top prediction from both methods was an interaction between the estrogen receptor (ER) and droloxifene, which had reached phase 3 clinical trials as an ER modulator for advanced breast cancer (25) . All of our findings were obtained without revealing any information about the underlying drugs, targets, and interactions during the computation.","[3.0, 1.0, 2.0, 3.0, 1.0]",Computer_Science,train,2.0,tweets,1052984059075293185
10.1016/j.neuroimage.2016.04.011,Computer_Science_tweet_239,NI: Media multitasking is associated with distractibility and increased prefrontal activity…  ,"It therefore seems likely that the higher the MMT score of a participant, the more effort or attentional top down control was needed when the participant needed to focus on a focal task in the presence of a distractor.",NI: Media multitasking is associated with distractibility and increased prefrontal activity…  ,"Page 28 of 38 this region increased incrementally in response to task difficulty. It therefore seems likely that the higher the MMT score of a participant, the more effort or attentional top down control was needed when the participant needed to focus on a focal task in the presence of a distractor. The current study extends previous findings on media multitasking in three important ways.","[3.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.25,tweets,722908493523496961
10.1098/rstb.2008.0288,Computer_Science_tweet_24,"Taxi Drivers study is now part of majority of the textbooks. This new awesome study complements that. Great work by @username, Katherine Woollett and Eleanor Maguire. Basically, use it or lose it :-) brain plasticity in action over many years ","While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences.","Taxi Drivers study is now part of majority of the textbooks. This new awesome study complements that. Great work by @username, Katherine Woollett and Eleanor Maguire. Basically, use it or lose it :-) brain plasticity in action over many years ","This was true even when taxi drivers were compared with another group of navigators, London bus drivers press; see figure 3a,b). While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences. Compared with controls, taxi drivers had greater grey matter volume in the posterior hippocampi (Maguire et al.","[4.0, 4.0, 3.0, 4.0, 2.0]",Computer_Science,train,3.4,tweets,1037782277995024384
10.1016/j.ijmedinf.2014.06.005,Computer_Science_tweet_240,The elderly community is gradually accepting #technology to track their #health  via @username,We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.,The elderly community is gradually accepting #technology to track their #health  via @username,Tools that activate this social network around our frail elders will help independent living and hopefully decrease caregiver burden on their children. What this study added to our knowledge We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.,"[1.0, 1.0, 2.0]",Computer_Science,train,1.3333333333333333,tweets,489113728571674625
10.1098/rspb.2018.0594,Computer_Science_tweet_241,"You might have heard me talking on BBC R4 this morning about mantis shrimp, their eyes and their suitability as a light supper.... well here's some science to go along with that:  

#mantisshrimp @username #stomatopods","However, overall the median maximum cross-correlation coefficient was not significantly different from 0 for yaw and torsion rotation, yaw and pitch rotations or pitch and torsion rotation (Wilcoxon signed-rank test, n ¼ 17, V ¼ 117, p .","You might have heard me talking on BBC R4 this morning about mantis shrimp, their eyes and their suitability as a light supper.... well here's some science to go along with that:  

#mantisshrimp @username #stomatopods","The median torsional pose relative to the horizontal was 67.34 + 0.128 (median + 95% CI, n ¼ 17) and the median pitch pose relative to the horizontal was 16.64 + 0.088 (median + 95% CI, n ¼ 17). However, overall the median maximum cross-correlation coefficient was not significantly different from 0 for yaw and torsion rotation, yaw and pitch rotations or pitch and torsion rotation (Wilcoxon signed-rank test, n ¼ 17, V ¼ 117, p . These findings demonstrate that stomatopods are able to independently rotate their eyes in the three degrees of rotational freedom, but that these rotations can become coupled in some instances, such as the yaw and torsion rotation during optokinesis shown in figure 2a,b.","[1.0, 1.0, 4.0, 2.0]",Computer_Science,train,1.0,tweets,991623421686681600
10.1038/s41467-018-05378-z,Computer_Science_tweet_242,"AI to predict the designer of a DNA sequence
",The identity of the nt post-mutation was one of the three nts not present at that position pre-mutation.,"AI to predict the designer of a DNA sequence
","The alignment of the entire pCI-YFP plasmid to the Addgene training set returned >10 4 matches. We found the smallest non-zero E-value (4 × 10 −180 ) and then counted the number of alignments with an E-value of zero to conclude that 11,369 plasmid alignments have an E-value < 10 −180 . The identity of the nt post-mutation was one of the three nts not present at that position pre-mutation.","[1.0, 2.0, 2.0, 1.0, 4.0]",Computer_Science,train,2.0,tweets,1026820307070464000
10.1038/s41598-018-31697-8,Computer_Science_tweet_245,Extracting video from a single image. ,"Furthermore, the results are largely unaffected by the motion of the scatterer, as can be seen by comparing them against the ground truth object.",Extracting video from a single image. ,"The single-shot coded ME approach, however, enables a clear understanding of the evolution of the scene (see Fig. Furthermore, the results are largely unaffected by the motion of the scatterer, as can be seen by comparing them against the ground truth object. For the results shown above, we typically set the camera integration time to approximately 100 s in order to overcome the readout detector noise on the CCD camera and achieve an excellent signal to noise ratio (SNR, typically 100).","[1.0, 1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.4,tweets,1047529037822873607
10.1073/pnas.1802407115,Computer_Science_tweet_246,@username @username @username @username @username out today:    -- on constant v. intermittent v. absent network ties.,"For example, when looked at through the lens of interaction frequency, the pattern of interaction studied in ref.",@username @username @username @username @username out today:    -- on constant v. intermittent v. absent network ties.,"Importantly, although past laboratory * Beyond guiding future work, our finding may also permit a reinterpretation of some prior results. For example, when looked at through the lens of interaction frequency, the pattern of interaction studied in ref. may be closer to IT than CT, presenting a possible explanation for the benefits of interaction described in that paper.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1029104867174952960
10.1073/pnas.1804420115,Computer_Science_tweet_247,CT @username/bioscience [1704.03009] Deep neural networks automate detection for tracking of submicron scale… ,"That is, P n is a connected set and p ijk ≥ 0.5 for all p ijk ∈ P n .",CT @username/bioscience [1704.03009] Deep neural networks automate detection for tracking of submicron scale… ,"Tensorflow can be easily adapted to use multiple cores of a CPU or GPU, depending on available hardware. That is, P n is a connected set and p ijk ≥ 0.5 for all p ijk ∈ P n . Note that there are alternative particle localization methods that may increase accuracy.","[1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.5,tweets,852019233676328961
10.1016/j.jbi.2015.05.016,Computer_Science_tweet_248,"#MachineLearning models for predicting early hospital readmissions.#BigData #DataScience #AI
 ","In particular, in elastic net the coefficientsb are found by 235 solving: which would give slightly better performance.","#MachineLearning models for predicting early hospital readmissions.#BigData #DataScience #AI
 ","forces some coefficients to be exactly zero. In particular, in elastic net the coefficientsb are found by 235 solving: which would give slightly better performance. However, 263 suggests this value is relatively robust, and we decided not to 264 tune it to save on computation costs, since our results using this 265 value were quite good.","[1.0, 2.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.4,tweets,777287528843993088
10.1080/10586458.2016.1270858,Computer_Science_tweet_249,progress on the sofa problem ,Our calculation works directly in the continuum regime and does not require taking a limit from the discrete variant of the problem.,progress on the sofa problem ,"Moreover, in Case 1 we have additionally that A (t) = 0 (that is, the contact point A remains fixed during an interval when Case 1 is applicable), and similarly in Case 5 we have that C (t) = 0. Our calculation works directly in the continuum regime and does not require taking a limit from the discrete variant of the problem. 3.","[2.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,844565142142697473
10.1126/scirobotics.aat1853,Computer_Science_tweet_25,"Are you up on the latest fashion in electronic skin?
tactile sensors and robotic


@username #OA ","Further, we show that combining multiple robotic skins enables complex motions and functions.","Are you up on the latest fashion in electronic skin?
tactile sensors and robotic


@username #OA ","We show that attaching the same robotic skin to a soft body in different ways, or to different soft bodies, leads to distinct motions. Further, we show that combining multiple robotic skins enables complex motions and functions. We demonstrate the versatility of this soft robot design approach in a wide range of applications-including manipulation tasks, locomotion, and wearables-using the same two-dimensional (2D) robotic skins reconfigured on the surface of various 3D soft, inanimate objects.","[3.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.0,tweets,1042527399143829504
10.3389/frobt.2017.00074,Computer_Science_tweet_250,Simulation-Based #Internal #Models for #Safer #Robots ,"From the mismatch between the trajectories and the arena walls, it is obvious that the calibration of the motion capturing system placed its coordinate system rotated by about 3° and also slightly offset.",Simulation-Based #Internal #Models for #Safer #Robots ,"There is a reality gap between every simulator and the physical object it represents. From the mismatch between the trajectories and the arena walls, it is obvious that the calibration of the motion capturing system placed its coordinate system rotated by about 3° and also slightly offset. This is due to the calibration process of the motion capturing system using a manually placed ground plate with markers to establish the motion capturing coordinate system.","[1.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.25,tweets,951320841106657280
10.1016/j.neuroimage.2018.09.045,Computer_Science_tweet_251,"New @username paper: #breastmilk intake in the weeks after preterm birth improves measures of brain network connectivity

Open access - 

@username @username @username ","Inter-hemispheric connections are shown in blue, and intra-hemispheric connections in magenta.","New @username paper: #breastmilk intake in the weeks after preterm birth improves measures of brain network connectivity

Open access - 

@username @username @username ","75% (a) and !90% (b). Inter-hemispheric connections are shown in blue, and intra-hemispheric connections in magenta. had higher FA in the higher breast milk group.","[2.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,1043047144037539840
10.1177/0018720812450587,Computer_Science_tweet_252,@username @username @username not heard of Sp.EarCons before - fascinating how far hearing can go ,Spearcons averaged 0.28 s (range = 0.14-0.46 s).,@username @username @username not heard of Sp.EarCons before - fascinating how far hearing can go ,"Therefore, spearcons are not simply ""fast talking"" menu items; they are distinct and unique sounds, albeit acoustically related to the original speech item. Spearcons averaged 0.28 s (range = 0.14-0.46 s). This was similar to the approach by .","[3.0, 1.0, 3.0, 2.0]",Computer_Science,train,2.25,tweets,835793105517490176
10.1177/1461444818776611,Computer_Science_tweet_253,Great work we were thrilled to support! ,It sounds like you could use some kind words right about now.,Great work we were thrilled to support! ,"Tumblr's approach to content moderation is different. It sounds like you could use some kind words right about now. We suggest Koko, an anonymous support community made up of nice, caring people like you.""","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1001393357980164096
10.1145/2441776.2441938,Computer_Science_tweet_254,reading: The Rise of the Urban War Correspondent on Twitter via @username  ,"The biggest spike in Monterrey (7,027 tweets) occurred on August 25, 2011, the day of an attack at a casino where 53 people were killed .",reading: The Rise of the Urban War Correspondent on Twitter via @username  ,"Second, we found that the number of daily tweets goes up and down constantly, spiking when violence erupts and decreasing when the city is calm (see Figure 1 ). The biggest spike in Monterrey (7,027 tweets) occurred on August 25, 2011, the day of an attack at a casino where 53 people were killed . For Veracruz, the biggest spike (4,699 tweets) also happened on August 25, 2011, during a seemingly unrelated event, when rumors of school children being kidnapped spread on social media .","[1.0, 2.0, 1.0, 4.0, 3.0]",Computer_Science,train,2.2,tweets,623077445726400512
10.1016/j.neunet.2019.01.006,Computer_Science_tweet_255,"Dreaming Neural Networks. #BigData #Analytics #MachineLearning #DataScience #AI #IoT #IIoT #Python #RStats #Java #JavaScript #ReactJS #VueJS #GoLang #Serverless #DataScientist #Linux 
 ","The replica symmetric assumption means that, in the thermodynamic limit N → ∞, the order parameters self-average over their averages (denoted hereafter by a bar), i.e.","Dreaming Neural Networks. #BigData #Analytics #MachineLearning #DataScience #AI #IoT #IIoT #Python #RStats #Java #JavaScript #ReactJS #VueJS #GoLang #Serverless #DataScientist #Linux 
 ","10 The latter, at least within a biological context, is fixed around O(10 2 ) Hertz, namely the typical spiking time (considering also the absolute refractory period of a biological neuron). The replica symmetric assumption means that, in the thermodynamic limit N → ∞, the order parameters self-average over their averages (denoted hereafter by a bar), i.e. lim N →∞ P (q) = δ(q −q) and lim N →∞ P (m) = δ(m −m), in such a way that the related fluctuations can be discarded.","[1.0, 1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.4,tweets,1096312878200750081
10.1088/1741-2560/13/2/026017,Computer_Science_tweet_256,"Cool. I think a better Brain Machine Interface paradigm is to use brain plasticity, not mapping actions to neurons. ",The LM used in the NSR system provides estimates for the a priori probabilities of phonemic sequences.,"Cool. I think a better Brain Machine Interface paradigm is to use brain plasticity, not mapping actions to neurons. ","The r 2 values for each relevant electrode for each subject are depicted in figure 2. The LM used in the NSR system provides estimates for the a priori probabilities of phonemic sequences. Approximately 4.3 million sentences were included, resulting in a phoneme corpus with about 76.9 million non-silence phonemes (a total of about 81.2 million phoneme tokens when /sp/ is included).","[1.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.5,tweets,702461762109624321
10.1038/srep41870,Computer_Science_tweet_257,@username the key would be not to assess punistive behavior that is grounded in desire for good reputation. ref: ,This leads to the second term in the sum for g X .,@username the key would be not to assess punistive behavior that is grounded in desire for good reputation. ref: ,Stern-judging assigns a good image to those who refuse help for a bad recipient and a bad image to those who give help for a bad recipient. This leads to the second term in the sum for g X . This conditional probability is (1 -e 1 )e 2 + e 1 (1 -e 2 ) = 1 -ε.,"[3.0, 1.0, 1.0, 3.0, 1.0]",Computer_Science,train,1.8,tweets,813754987331387392
10.1038/s42256-019-0029-0,Computer_Science_tweet_258,"A robotic leg, born without prior knowledge, learns to walk - New AI algorithms could allow robots to learn to move by themselves, imitating animals. Nice work from @username #robotics #walking #AI ",We detect no right-to-left trend indicating that energy consumption was spontaneously reduced as performance improved.,"A robotic leg, born without prior knowledge, learns to walk - New AI algorithms could allow robots to learn to move by themselves, imitating animals. Nice work from @username #robotics #walking #AI ","These movements can, in principle, propel the treadmill. We detect no right-to-left trend indicating that energy consumption was spontaneously reduced as performance improved. Conversely, higher reward did not always require higher energy consumption even though more external work was being done to propel the treadmill the furthest.","[1.0, 2.0, 3.0]",Computer_Science,train,2.0,tweets,1105583214523965440
10.1126/sciadv.1602368,Computer_Science_tweet_259,"Memory Remains: Understanding Collective
Memory in the Digital Age, the Case of Air-crashes  ","Our analysis has also been applied to the complete set of sources, which yielded the following changes to the results: The average view flow is a full scale smaller, and the noise is a bit more dominant.","Memory Remains: Understanding Collective
Memory in the Digital Age, the Case of Air-crashes  ","We removed all sources below the 11th largest source because the natural noise of the target views dominates in this region, as illustrated in Fig. Our analysis has also been applied to the complete set of sources, which yielded the following changes to the results: The average view flow is a full scale smaller, and the noise is a bit more dominant. The effects of categories and geography are enhanced, whereas the superlinear effect of the previous views on the view flow almost disappears.","[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,tweets,775125077046222848
10.1038/s41562-017-0273-4,Computer_Science_tweet_26,From wisdom of crowds to the power of deliberation: Talking with each other seems to make us humans smarter? ,But the evidence is not exhaustive and does not necessarily imply positive evidence for the hypothesis that our crowd shared arguments during deliberation.,From wisdom of crowds to the power of deliberation: Talking with each other seems to make us humans smarter? ,"The above analysis definitively rejects the more simplified models of consensus. But the evidence is not exhaustive and does not necessarily imply positive evidence for the hypothesis that our crowd shared arguments during deliberation. The procedure with highest endorsement was ""We shared arguments and reasoned together"" (mean rating ± s.e.m across all questions: 7.7 ± 0.2, mode rating: 10; z > 7.05, P < 10 −12 for all comparisons, Table 1 ).","[5.0, 2.0, 3.0, 2.0, 3.0]",Computer_Science,train,3.0,tweets,952939095516426242
10.1186/s12911-017-0477-6,Computer_Science_tweet_260,"Impact of diagnostic decision support system on pt consultation

@username @username @username @username",This could be a potential barrier to adoption.,"Impact of diagnostic decision support system on pt consultation

@username @username @username @username","However, to use the DSS effectively, GPs would need to adapt their consultation style, so that they code more information during rather than at the end of the consultation. This could be a potential barrier to adoption. Training GPs to use the system in a patient-centred way, as well as improvement of the DSS interface itself, could facilitate coding.","[5.0, 1.0, 1.0, 2.0]",Computer_Science,train,1.0,tweets,883090072446349312
10.1016/j.joi.2015.07.006,Computer_Science_tweet_261,How quickly we forget. ,"Assuming that the rate of transition between states is X ti and X tj is exp −µd(Xt i ,Xt j ) , with µ being the scaling function, and, the probability of citing the paper is 1 when the peak in the number of citations is reached, the probability of citing the paper at time t is given by P Xt n−t0 (t).",How quickly we forget. ,"The autocorrelation function has an exact solution for an ultrametric space defined by a hierarchical tree. Assuming that the rate of transition between states is X ti and X tj is exp −µd(Xt i ,Xt j ) , with µ being the scaling function, and, the probability of citing the paper is 1 when the peak in the number of citations is reached, the probability of citing the paper at time t is given by P Xt n−t0 (t). When the number of states is finite, such an autocorrelation function is exponential in nature, otherwise it follows a power law behavior .","[2.0, 3.0, 1.0, 2.0]",Computer_Science,train,2.0,tweets,577208109799645184
10.1145/2996183,Computer_Science_tweet_262,Spark Streaming to do this in real-time? ,The retweet ratio suggests that other users pick up on event commentaries and propagate them further through the network.,Spark Streaming to do this in real-time? ,are good discriminators. The retweet ratio suggests that other users pick up on event commentaries and propagate them further through the network. Another important observation in Figure 5 is that the negative sentiment model outperforms the positive sentiment model in NDCG scores.,"[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,855302364391067648
10.1073/pnas.0403723101,Computer_Science_tweet_263,"@username Also, this: ","Our perspective-heuristic framework is not minimal, because we show in an earlier paper (8) that two problem solvers with distinct perspectives and heuristics can act identically in the space of solutions.","@username Also, this: ","A diverse group is one whose agents' mappings are diverse. Our perspective-heuristic framework is not minimal, because we show in an earlier paper (8) that two problem solvers with distinct perspectives and heuristics can act identically in the space of solutions. However, the advantage of the full framework is that it generalizes models in the computer science literature that focus on diverse heuristics (1, 2), and models in the organizational behavior and psychology literature, which often emphasize diverse perspectives (3, 4, 6).","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,95940464787734529
10.1093/bioinformatics/btu618,Computer_Science_tweet_264,@username Oh no! Thanks for letting us know. Here's the link to the abstract of the article that details the tool ,"The median estimate is close to the true value of 0.5, and the spread of the estimates is small.",@username Oh no! Thanks for letting us know. Here's the link to the abstract of the article that details the tool ,"The bottom panel of Figure 2 shows that GLAD is accurate across a wide range of sample sizes for mixed samples. The median estimate is close to the true value of 0.5, and the spread of the estimates is small. In contrast, LPD has a large variance across a range of sample sizes, and it appears to exhibit some bias, which does not disappear even at N = 6000.","[1.0, 1.0, 1.0, 2.0, 1.0]",Computer_Science,train,1.2,tweets,544572210481209345
10.1038/s41586-018-0520-5,Computer_Science_tweet_265,Looks like another sick pape from @username  ,The formation of this auditory cortical filter required a predictable and relatively prolonged association of movement with an ensuing sound.,Looks like another sick pape from @username  ,"3b-d ), indicating that circuits local to the auditory cortex are a likely source of the reafferent notch filter that arises following aVR experience. The formation of this auditory cortical filter required a predictable and relatively prolonged association of movement with an ensuing sound. Mice acclimated for about a week on a treadmill in which fixed-frequency tones were presented only at rest did not display enhanced cortical suppression at the training frequency during rest or running (Extended Data Fig.","[4.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.8,tweets,1039926090658197504
10.1016/j.neuroimage.2014.03.080,Computer_Science_tweet_267,Reduced self-referential neural response during i... [Neuroimage. 2014] - PubMed - NCBI ,"Typically, individuals show better subsequent memory for items encoded with regard to the self, compared to other encoding conditions; this memory advantage is associated with mPFC activation.",Reduced self-referential neural response during i... [Neuroimage. 2014] - PubMed - NCBI ,"These results are consistent with the complexity of intergroup behavior, demonstrating that for some but not all individuals, competing in a group is associated with reduced mPFC response to self-relevant moral stimuli, and this reduction is associated with a greater propensity to harm competitors. Typically, individuals show better subsequent memory for items encoded with regard to the self, compared to other encoding conditions; this memory advantage is associated with mPFC activation. Consistent with past research, we observed a positive correlation across individuals between the self-reference effect in memory and the self-reference effect in mPFC in the ""alone"" condition, r(19)=.47, p=.03.","[1.0, 1.0, 4.0, 1.0, 3.0]",Computer_Science,train,1.0,tweets,488931748521078784
10.1186/2051-3933-1-3,Computer_Science_tweet_268,#Zmove Env-DATA: linking animal tracks with environmental data - useful paper &amp; great tool added to MoveBank ,"For instance, for categorical data, such as land-use type, only the nearest neighbor interpolation can be applied, whereas for continuousnumeric data types either a nearest neighbor, bilinear (in regular grids), or inverse weighted distance interpolation can be selected based on the resolution of data .",#Zmove Env-DATA: linking animal tracks with environmental data - useful paper &amp; great tool added to MoveBank ,"The user can apply different methods of interpolation to space and to time. For instance, for categorical data, such as land-use type, only the nearest neighbor interpolation can be applied, whereas for continuousnumeric data types either a nearest neighbor, bilinear (in regular grids), or inverse weighted distance interpolation can be selected based on the resolution of data . Metadata for the output is uniform across different annotation requests and movement data types, which simplifies linking the output with further analysis tools.","[2.0, 1.0, 1.0, 3.0, 2.0]",Computer_Science,train,1.8,tweets,372011861572464640
10.1509/jmr.14.0591,Computer_Science_tweet_27,Calendar-Scheduling a leisure activity (vs. experiencing it impromptu) takes fun out of it.  ,We suggest that both sources of utility can be diminished for scheduled leisure.,Calendar-Scheduling a leisure activity (vs. experiencing it impromptu) takes fun out of it.  ,"However, unlike the prior research demonstrating how work versus leisure goals alter the experience of an ambiguous activity, we argue that a subtle manipulation (i.e., scheduling) of an unambiguous leisure activity can make the activity feel more like work and decrease utility. We suggest that both sources of utility can be diminished for scheduled leisure. Together, our results provide support for the detrimental effect of scheduling on how leisure activities are anticipated and experienced.","[3.0, 4.0, 2.0, 3.0, 3.0]",Computer_Science,train,3.0,tweets,714721618405228545
10.1145/2818048.2820065,Computer_Science_tweet_270,Our latest work accepted at #cscw2016! Style in the Age of Instagram: Predicting Success within the Fashion Industry ,"In particular, we find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry.",Our latest work accepted at #cscw2016! Style in the Age of Instagram: Predicting Success within the Fashion Industry ,"Our framework successfully predicts most of the new popular models who appeared in 2015. In particular, we find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry. Accepted for presentation at CSCW '16 Modeling has in fact a very special meaning in fashion, a multi-billion dollar industry with strong social and economical implications worldwide .","[3.0, 4.0, 1.0]",Computer_Science,train,2.0,tweets,633882448187772928
10.1038/s41528-018-0025-1,Computer_Science_tweet_271,Very intriguing... ,"The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision.",Very intriguing... ,"The geometrical ""net"" architecture along with the intrinsic stretchable properties of PDMS, allow the system to conform to the body of the animal and stretch/ contract with their movements, ensuring comfort and adhesion under any circumstance. The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision. 2 , showing compliant 3D integration of the SoC on top of the sensory array ( Fig.","[1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,993379374132056064
10.1038/s41586-018-0766-y,Computer_Science_tweet_272,"
S Wengerowsky et. al.
Entanglement-based wavelength multiplexed quantum communication network ","On the other hand, a TDM based scheme would need only 2N channels.","
S Wengerowsky et. al.
Entanglement-based wavelength multiplexed quantum communication network ","Lastly, crosstalk between the channels is not harmful, since photons in the wrong channel would, due to the different delay introduced by the WDMs, only contribute to the accidental rate and not be seen as a separate coincidence peak. On the other hand, a TDM based scheme would need only 2N channels. Large scale networks could also combine the advantages of WDMs and TDMs by using both together.","[1.0, 1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,955262550115053568
10.1038/s41598-018-30619-y,Computer_Science_tweet_273,"Oh, this @username research sounds promising: offloading computation to an optical computer inside a camera might help it  recognize objects using less power

 ","Since the actual phase mask had only 16 discrete heights instead of the continuous heights allowed in the phase mask optimization, the PSF produced by the physical phase mask, though very similar, did not exactly match the target PSF.","Oh, this @username research sounds promising: offloading computation to an optical computer inside a camera might help it  recognize objects using less power

 ","The prototype test accuracy falls slightly below the simulated opt-conv test accuracy of 51.0%, likely due to hardware imperfections unaccounted for in simulation. Since the actual phase mask had only 16 discrete heights instead of the continuous heights allowed in the phase mask optimization, the PSF produced by the physical phase mask, though very similar, did not exactly match the target PSF. In addition, the boundaries of the convolved sub-images may not have precisely aligned with the sensor pixels due to the different pixel sizes of the DMD and camera sensor, resulting in alignment imperfections when subtracting kernels to yield the pseudonegative sub-images.","[1.0, 1.0, 1.0, 2.0, 2.0]",Computer_Science,train,1.4,tweets,1030477945339490304
10.1073/pnas.1606075113,Computer_Science_tweet_274,"""[The algorithm] didn’t find some bizarre solution, it found the same one Nature uses.""  ","For the learned policies in the regimes of moderate and strong turbulence levels, the glider adopts an increasingly conservative policy as turbulence levels increase, quantifying the degree of risk affordable in turbulent environments.","""[The algorithm] didn’t find some bizarre solution, it found the same one Nature uses.""  ","Furthermore, the problem is technologically relevant to extend the flying range of autonomous gliders. For the learned policies in the regimes of moderate and strong turbulence levels, the glider adopts an increasingly conservative policy as turbulence levels increase, quantifying the degree of risk affordable in turbulent environments. Reinforcement learning uncovers those sensorimotor cues that permit effective control over soaring in turbulent environments.","[1.0, 1.0, 2.0, 4.0]",Computer_Science,train,1.0,tweets,760273885543534592
10.1016/j.neuroimage.2016.11.025,Computer_Science_tweet_275,"@username @username @username Looks great! here are some links to studies that are relevant. Work by the excellent @username, @username
 and others!







","In contrast, our results suggest that a different pattern of cortical organization may underlie reports of spontaneous mind-wandering: In particular, participants who reported higher rates of spontaneous mind-wandering tended to have cortical thinning in left angular gyrus within the DMN, extending to regions in the IPS implicated in executive control (Fig.","@username @username @username Looks great! here are some links to studies that are relevant. Work by the excellent @username, @username
 and others!







","The observation that higher deliberate mind-wandering was associated clusters in both the DMN and FPN suggests that the process of mind-wandering in a deliberate manner depends, in part, on the integration of the executive control and default mode networks as predicted by contemporary accounts of this experience (see . In contrast, our results suggest that a different pattern of cortical organization may underlie reports of spontaneous mind-wandering: In particular, participants who reported higher rates of spontaneous mind-wandering tended to have cortical thinning in left angular gyrus within the DMN, extending to regions in the IPS implicated in executive control (Fig. 4) .","[1.0, 1.0, 2.0]",Computer_Science,train,1.3333333333333333,tweets,988458763203104768
10.1016/j.neuroimage.2017.01.001,Computer_Science_tweet_278,New paper from Zaghoul lab showing both nested oscillation and sharp-wave PAC during memory encoding with ECoG: ,This amplitude should not be significantly impacted by the presence or absence of any high frequency oscillations.,New paper from Zaghoul lab showing both nested oscillation and sharp-wave PAC during memory encoding with ECoG: ,"The amplitude of the phase-triggered average waveform reflects a combination of both the consistency and the strength of the modulating low frequency signal. This amplitude should not be significantly impacted by the presence or absence of any high frequency oscillations. We found that, in an exemplar electrode, the amplitude of the average waveform is significantly correlated with the extent to which PAC was measured across all trials (r=0.663, p < .001; Fig.","[1.0, 3.0, 2.0, 4.0, 1.0]",Computer_Science,train,2.2,tweets,818878929931014144
10.1145/3128572.3140448,Computer_Science_tweet_279,@username @username @username @username Or you can directly use gradient-free optimization on the target model: ,"To just obtain the estimated gradients of all pixels, 2p = 536, 406 evaluations are needed.",@username @username @username @username Or you can directly use gradient-free optimization on the target model: ,"For example, the Inception-v3 network takes input images with a size of 299 × 299 × 3, and thus has p = 268, 203 variables (pixels) to optimize. To just obtain the estimated gradients of all pixels, 2p = 536, 406 evaluations are needed. For a model as large as Inception-v3, each evaluation can take tens of milliseconds on a single GPU, thus it is very expensive to even evaluate all gradients once.","[2.0, 3.0, 1.0]",Computer_Science,train,2.0,tweets,933738434996289536
10.1111/j.1083-6101.2012.01584.x,Computer_Science_tweet_280,People laugh more and are happier in face-to-face or video conferencing meetings - less so in teleconf  #eventprofs,"Whilst the duration of the interaction for FTF positively predicted happiness, there was no effect of duration on happiness for the other modes, including those CMC modes that included auditory cues (Skype and telephone).",People laugh more and are happier in face-to-face or video conferencing meetings - less so in teleconf  #eventprofs,"Hypothesis 1 was only partially supported. Whilst the duration of the interaction for FTF positively predicted happiness, there was no effect of duration on happiness for the other modes, including those CMC modes that included auditory cues (Skype and telephone). Results showed robust support for Hypothesis 2.","[4.0, 4.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.6,tweets,301623048967172096
10.1016/j.eswa.2014.03.024,Computer_Science_tweet_282,@username thanks a lot! There are 2 papers: the first:  and the second you might refer to: ,"Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well.",@username thanks a lot! There are 2 papers: the first:  and the second you might refer to: ,"It has to be repeated m times, so the worst computational cost is O(m 2 n), or O(n 3 ) for sparse graphs. Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well. The number of the edges to be deleted can be chosen interactively.","[1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,456474967740133378
10.1038/s41598-019-44221-3,Computer_Science_tweet_283,"Measuring mice calls can tell us how disease progresses, act as an index of social interest, motivation, emotional development or motor function. But how can we best describe these calls - our paper with @username @username shows one way  @username ",Element separation is required where components of the call have different amplitudes.,"Measuring mice calls can tell us how disease progresses, act as an index of social interest, motivation, emotional development or motor function. But how can we best describe these calls - our paper with @username @username shows one way  @username ","Specifically, we note the following characteristics for each call class: (1) Complex calls included one component containing two or more directional changes in frequency, each ≥6.25 kHz; (2) Two-component calls have two parts: a main call (flat or downward) with an additional shorter component at a different frequency towards the end; (3) Upward calls are a single harmonic that increases in frequency ≥12.5 kHz from beginning to end; (4) Downward calls follow the opposite trajectory to Upward calls, with a single harmonic that decreases in frequency ≥12.5 kHz from beginning to end; (5) Chevron calls resemble an 'inverted-U'; (6) Short calls are brief single harmonic calls ≤5 ms; Composite calls are formed by two harmonically independent components emitted simultaneously at different frequencies; (8) Frequency step calls include multiple instantaneous frequency harmonics appearing as a vertically discontinuous ""step"" on a spectrogram, but with no interruption in time; Flat calls are a single constant harmonic at a stable frequency (≤3 kHz change). Element separation is required where components of the call have different amplitudes. Adjustment of the hold threshold length is necessary where calls may have extended pauses between components (see Table 2 for settings for call types).","[2.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.25,tweets,1134092934540697600
10.1007/s10916-017-0778-4,Computer_Science_tweet_285,"Great read on security in EMR's. 

#OUInformaticsFall12019","This processed reduced the final group for analysis to 25 (7 from PubMed, 7 from CINAHL, 11 from ProQuest).","Great read on security in EMR's. 

#OUInformaticsFall12019","This reduced the number of articles to 133 (41 Pubmed, 34 CINAHL, 58 ProQuest). This processed reduced the final group for analysis to 25 (7 from PubMed, 7 from CINAHL, 11 from ProQuest). The final group for analysis was 25.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1176950706412150785
10.1145/2675133.2675290,Computer_Science_tweet_286,@username @username Facebook employees are actually writing research papers on this ,"Whereas .8% of individuals who did not Table 1 : Adoption Probability for Exposed Users, by Age and Gender list any education level adopted, 1.0% of high school graduates did so, the proportion increasing to 2.4% for users with college degrees and to 4.6% for users with graduate educations.",@username @username Facebook employees are actually writing research papers on this ,"Individuals who listed higher education were also more likely to display the equal sign picture than those individuals not listing education. Whereas .8% of individuals who did not Table 1 : Adoption Probability for Exposed Users, by Age and Gender list any education level adopted, 1.0% of high school graduates did so, the proportion increasing to 2.4% for users with college degrees and to 4.6% for users with graduate educations. Individuals listing themselves as ""Interested in"" persons of the same gender as themselves were 8 times more likely (11.0%) to adopt the equal sign than individuals whose ""Interested in"" field indicated persons of the opposite gender (1.4%).","[2.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.2,tweets,615703534600765440
10.1145/3025453.3025635,Computer_Science_tweet_287,Examining #Menstrual Tracking to Inform the Design of Personal Informatics Tools  HT @username ,"We adopt many aspects of Bardzell and Bardzell's Feminist HCI methodology , such as indicating our goals as technologists in our interactions with participants.",Examining #Menstrual Tracking to Inform the Design of Personal Informatics Tools  HT @username ,"In our work, we highlight ways in which tracking apps fail to support the marginalized populations of gender and sexual minorities. We adopt many aspects of Bardzell and Bardzell's Feminist HCI methodology , such as indicating our goals as technologists in our interactions with participants. However, our research team's expertise is in personal informatics technology, rather than feminist theory.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,865721263871971328
10.1126/sciadv.aap9815,Computer_Science_tweet_288,"Und deshalb bleiben so viele eurer Liebesbriefe unbeantwortet:
""We find that both men and women pursue partners who are on average about 25% more desirable than themselves"" 
","The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones.","Und deshalb bleiben so viele eurer Liebesbriefe unbeantwortet:
""We find that both men and women pursue partners who are on average about 25% more desirable than themselves"" 
","The lower set of curves in the top panels shows the probability of receiving a reply to an initial message. The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones. The differences are stark: men are more than twice as likely to receive a reply from women less desirable than themselves than from more desirable ones, and for messages sent to more desirable women the reply rate never rises above 21%.","[4.0, 2.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.2,tweets,1027461774055014401
10.1126/science.aaf2654,Computer_Science_tweet_29,"Autonomous Vehicles Need Experimental Ethics: 
Are We Ready for Utilitarian Cars?
 ","To align moral algorithms with human values, we must start a collective discussion about the ethics of AVs, that is, the moral algorithms that we are willing to accept as citizens and to be subjected to as car owners.","Autonomous Vehicles Need Experimental Ethics: 
Are We Ready for Utilitarian Cars?
 ","Even though such situations may be exceedingly rare, their emotional saliency is likely to give them broad public exposure and a disproportionate weight in individual and public decisions about AVs. To align moral algorithms with human values, we must start a collective discussion about the ethics of AVs, that is, the moral algorithms that we are willing to accept as citizens and to be subjected to as car owners. A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far.","[3.0, 3.0, 4.0, 2.0, 1.0]",Computer_Science,train,2.6,tweets,654196955149692928
10.1126/science.aam6383,Computer_Science_tweet_290,#fMRI reveals #social #interaction #network in #medial and #ventrolateral #prefrontal #cortex in #macaque #monkeys ,When mapping the MNS in this way ( fig.,#fMRI reveals #social #interaction #network in #medial and #ventrolateral #prefrontal #cortex in #macaque #monkeys ,"The classical MNS can be mapped in monkeys with fMRI by using videos of humans grasping objects (16) . When mapping the MNS in this way ( fig. S3B and movie S3) , it colocalized with pAIP and F5 interaction areas (Fig.","[1.0, 4.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,866647678133972997
10.1162/jocn_a_00450,Computer_Science_tweet_291,"Context is everything: ""LIGHT is an important regulator of wakefulness and cognition"" ",No classical visual responses were detected in any tests.,"Context is everything: ""LIGHT is an important regulator of wakefulness and cognition"" ","Visual acuity tests previously performed in Boston indicated no light perception in either eye of the three participants. No classical visual responses were detected in any tests. Finally, questionnaire scores indicated that Participants 2 and 3 reported, respectively, relatively poor sleep quality and high propensity to fall asleep during the day (Table 1 ).","[3.0, 1.0, 1.0]",Computer_Science,train,1.6666666666666667,tweets,579024119636701184
10.1016/j.neuroimage.2016.05.037,Computer_Science_tweet_292,"Lithium increases NAA 
Which is a biomarker of fluid intelligence 
So lithium increases IQ?","Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex).","Lithium increases NAA 
Which is a biomarker of fluid intelligence 
So lithium increases IQ?","The relationship of the PCC to regions involved in these final two stages, in concert with our results demonstrating PCC NAA to predict fluid reasoning ability, suggest that oxidative metabolism in the PCC may be reflective of high functioning in the frontal-parietal network responsible for hypothesis and response formation. Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex). The additional domains of cognition measured by our battery may provide clues about the relationship of NAA to Gf.","[4.0, 1.0, 1.0, 3.0]",Computer_Science,train,1.0,tweets,780225355932049408
10.1073/pnas.1821740116,Computer_Science_tweet_293,Welp indeed @username ,"For a single reporter gene controlled by a gRNA, we observed dosedependent repression (SI Appendix, Fig.",Welp indeed @username ,"1 observed correct circuit performance after 24 h, although the performance was improved after 48 h (SI Appendix, Fig. For a single reporter gene controlled by a gRNA, we observed dosedependent repression (SI Appendix, Fig. Addition of auxin shut off the circuit within 4 h, while removal of auxin from the medium restored the circuit function (SI Appendix, Fig.","[1.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.25,tweets,1123651539925708801
10.1016/j.cub.2013.11.014,Computer_Science_tweet_294,".@username: whatever the solution, data must be curated better. think of recent study by @username: ","Our proportions for 10-year-old e-mails are lower, with only 51% of e-mails from 2003 returning an error.",".@username: whatever the solution, data must be curated better. think of recent study by @username: ","reported a steep decline with age in the proportion of functioning e-mails from papers published between 1995 and 2004, such that 84% of their 10-year-old e-mails returned an error message. Our proportions for 10-year-old e-mails are lower, with only 51% of e-mails from 2003 returning an error. It may be that e-mail addresses are becoming more stable through time, although this clearly requires additional study.","[1.0, 4.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,472026832544735232
10.1016/j.jocs.2010.12.007,Computer_Science_tweet_295,RT @username: @username: Can Twitter trends help you beat the stock market?  Pdf ,"For example, shows how online chat activity predicts book sales.",RT @username: @username: Can Twitter trends help you beat the stock market?  Pdf ,"This may conceivably also be the case for the stock market. For example, shows how online chat activity predicts book sales. Although news most certainly influences stock market prices, public mood states or sentiment may play an equally important role.","[3.0, 3.0, 4.0, 3.0]",Computer_Science,train,3.25,tweets,112545364015448064
10.1126/sciadv.aap9815,Computer_Science_tweet_297,"i'M a SaPiOsExUaL 
 ","The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones.","i'M a SaPiOsExUaL 
 ","The lower set of curves in the top panels shows the probability of receiving a reply to an initial message. The curves are higher for messages sent by women than for those sent by men-women are more likely than men to receive replies-but among both women and men the probability of a reply is a decreasing function of desirability gap, more desirable partners replying at lower rates than less desirable ones. The differences are stark: men are more than twice as likely to receive a reply from women less desirable than themselves than from more desirable ones, and for messages sent to more desirable women the reply rate never rises above 21%.","[1.0, 1.0, 1.0, 1.0, 1.0]",Computer_Science,train,1.0,tweets,1098030869376163840
10.1016/j.eswa.2014.03.024,Computer_Science_tweet_299,#BigData and #networking to detect criminal organizations in mobile phone networks @username  #LogAnalysis ,"Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well.",#BigData and #networking to detect criminal organizations in mobile phone networks @username  #LogAnalysis ,"It has to be repeated m times, so the worst computational cost is O(m 2 n), or O(n 3 ) for sparse graphs. Note that, although for large networks such high computational cost makes this solution often unfeasible, for criminal networks constituted (most often) by hundreds or at most thousands of nodes, this algorithm works well. The number of the edges to be deleted can be chosen interactively.","[3.0, 3.0, 4.0, 5.0]",Computer_Science,train,3.75,tweets,456429141974581248
10.1007/s10055-018-0346-3,Computer_Science_tweet_3,"Personalized VR memory palaces are totally going to be a thing!
""We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition."" ","If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.","Personalized VR memory palaces are totally going to be a thing!
""We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition."" ","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.","[3.0, 4.0, 5.0]",Computer_Science,train,4.0,tweets,1155117313504374784
10.1007/s10055-018-0346-3,Computer_Science_tweet_30,"People recall information better through virtual reality, says new study at University of Maryland
 
",We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces.,"People recall information better through virtual reality, says new study at University of Maryland
 
",We found that virtual memory palaces in HMD condition provide a superior memory recall ability compared to the desktop condition. We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"[3.0, 3.0, 4.0, 3.0, 4.0]",Computer_Science,train,3.4,tweets,1008975215957856256
10.1126/science.aaj2038,Computer_Science_tweet_32,Read @username study in @username about big data stored in a drop of DNA: ,DNA is an attractive medium to store digital information.,Read @username study in @username about big data stored in a drop of DNA: ,"DNA is an attractive medium to store digital information. Finally, we explored the limit of our architecture in terms of bytes per molecule and obtained a perfect retrieval from a density of 215 petabytes per gram of DNA, orders of magnitude higher than previous reports. DNA is an excellent medium for data storage, owing to its demonstrated information density of petabytes of data per gram, high durability, and evolutionarily optimized machinery to faithfully replicate this information (1, 2).","[4.0, 5.0, 4.0, 1.0]",Computer_Science,train,4.0,tweets,837377636582232064
10.1016/j.neuroimage.2016.05.037,Computer_Science_tweet_33,"@username Brain 'markers' of numeric, verbal &amp; spatial reasoning abilities found!
","Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex).","@username Brain 'markers' of numeric, verbal &amp; spatial reasoning abilities found!
","The relationship of the PCC to regions involved in these final two stages, in concert with our results demonstrating PCC NAA to predict fluid reasoning ability, suggest that oxidative metabolism in the PCC may be reflective of high functioning in the frontal-parietal network responsible for hypothesis and response formation. Furthermore, our results provide preliminary evidence that this network of brain regions may be less related to quantitative reasoning and more exclusively related to verbal and/or spatial reasoning processes (perhaps depending on sex). The additional domains of cognition measured by our battery may provide clues about the relationship of NAA to Gf.","[4.0, 2.0, 4.0, 2.0]",Computer_Science,train,3.0,tweets,748692655127797764
10.1007/s10994-006-6226-1,Computer_Science_tweet_34,"Amazing. The Extra-Trees algorithm, see  ,  that I codesigned, is described in this new #machinelearning  book ","The geometrical analysis has shown that Extra-Trees asymptotically produce continuous, piecewise multi-linear functions.","Amazing. The Extra-Trees algorithm, see  ,  that I codesigned, is described in this new #machinelearning  book ","Furthermore, we have highlighted the different nature of the bias/variance tradeoff in classification and regression problems, explaining why classification problems can take advantage of stronger randomization. The geometrical analysis has shown that Extra-Trees asymptotically produce continuous, piecewise multi-linear functions. The resulting models are thus smoother than the piecewise constant ones obtained with other ensemble methods which optimize the cut-points.","[3.0, 2.0, 3.0, 4.0]",Computer_Science,train,3.0,tweets,865864073807888384
10.1016/j.neuroimage.2018.09.009,Computer_Science_tweet_37,"A really important meta-analysis (36 studies, 1150 participants) of altruistic and strategic decisions to give
ft. @username 

Conclusion:
Altruistic and strategic prosociality aren't interchangeable in brain (to wit, in reward and social cognition areas). ","For altruistic giving compared to rest, AI and ACC activity could underlie empathy .","A really important meta-analysis (36 studies, 1150 participants) of altruistic and strategic decisions to give
ft. @username 

Conclusion:
Altruistic and strategic prosociality aren't interchangeable in brain (to wit, in reward and social cognition areas). ","Finally, these activations could represent different processes in each context. For altruistic giving compared to rest, AI and ACC activity could underlie empathy . More relevant for risky strategic giving , ACC activation could reflect greater ambiguity or risk or an increase in effort and prediction .","[2.0, 3.0, 2.0, 2.0]",Computer_Science,train,2.25,tweets,1039141462015963137
10.1073/pnas.1800485115,Computer_Science_tweet_38,1) a relatively constrained number of ideas and scholars lead science 2) there are  key pathways by which knowledge systematically gains credit and spreads through the network 3) genealogical and co authorship networks strongly predict who wins one or more prizes ,"The pie of prizes expanded, but a smaller group of scholars received bigger slices.",1) a relatively constrained number of ideas and scholars lead science 2) there are  key pathways by which knowledge systematically gains credit and spreads through the network 3) genealogical and co authorship networks strongly predict who wins one or more prizes ,"1B) , we observe that prizewinning has also become more concentrated within a small set of prizewinners. The pie of prizes expanded, but a smaller group of scholars received bigger slices. This uneven distribution of prizes per scientist is evident along several measures shown in Fig.","[1.0, 3.0, 2.0]",Computer_Science,train,2.0,tweets,1034640325309018112
10.1038/s41598-018-38277-w,Computer_Science_tweet_39,Our latest paper with @username about multisensory grasping is now out in @username. The simultaneous availability of both visual and haptic (proprioceptive) information about the target object substantially improves reach-to-grasp actions.  ,"When movements were based on haptic information only, hand preshaping was initiated earlier, the digits closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information.",Our latest paper with @username about multisensory grasping is now out in @username. The simultaneous availability of both visual and haptic (proprioceptive) information about the target object substantially improves reach-to-grasp actions.  ,"However, planning and execution of grasping movements can be supported also by haptic information when we grasp objects held in the other hand. When movements were based on haptic information only, hand preshaping was initiated earlier, the digits closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information. Importantly, the simultaneous availability of vision and haptics led to faster movements and to an overall decrease of the grip aperture.","[5.0, 2.0, 3.0, 3.0]",Computer_Science,train,3.25,tweets,1103284172666429440
10.1287/orsc.2013.0878,Computer_Science_tweet_4,Competition between groups increases creativity in groups composed of men. Has opposite effect of female groups ,"When groups are forced to go head-to-head with each other, we expect those composed of men to exhibit higher levels of creativity relative to groups composed of women.",Competition between groups increases creativity in groups composed of men. Has opposite effect of female groups ,"When operating in a competitive environment, however, this pattern is likely to change. When groups are forced to go head-to-head with each other, we expect those composed of men to exhibit higher levels of creativity relative to groups composed of women. Our explanation for this pattern again relies primarily on social role theory.","[4.0, 4.0, 5.0]",Computer_Science,train,4.333333333333333,tweets,415064670656299008
10.1038/srep45898,Computer_Science_tweet_40,High-resolution decoding of bionic prosthesis stimulation in neocortical neurons.  #bionic #hplus #neuroscience,"Such complementariness could allow for co-operative decoding within a small population of neurons, which together might provide a much higher capacity to segregate spatiotemporal patterns of tactile afferent input.",High-resolution decoding of bionic prosthesis stimulation in neocortical neurons.  #bionic #hplus #neuroscience,"2E) , this hinted at the possibility of complementary decoding between neurons. Such complementariness could allow for co-operative decoding within a small population of neurons, which together might provide a much higher capacity to segregate spatiotemporal patterns of tactile afferent input. The temporal spike response patterns could be widely different between two adjacent neurons ( Fig.","[3.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.25,tweets,849233487790055424
10.1073/pnas.1419704112,Computer_Science_tweet_42,Smaller populations have higher rates of word loss. #language&amp;evolution ,"Despite the likely establishment of new Polynesian languages from relatively small colonizing populations, we do not find that a founder model describes our data better than one of gradual loss of words.",Smaller populations have higher rates of word loss. #language&amp;evolution ,"Although a small population of founders cannot carry all of the genetic alleles of a large parent population, it may be possible for a small number of speakers to use all of the basic vocabulary from the parent language (40). Despite the likely establishment of new Polynesian languages from relatively small colonizing populations, we do not find that a founder model describes our data better than one of gradual loss of words. If the finding that rates of word gain are greatest in large populations is a general feature of language change, then it has implications for understanding the connection between rate of language change and the diversification of language families.","[3.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.0,tweets,567158802978332673
10.1111/j.1083-6101.2007.00367.x,Computer_Science_tweet_43,"THE BENEFITS OF FACEBOOK “FRIENDS”

In a study by Lampe, Ellison and Steinfeld (2007) the relationship between... ",H4b: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's satisfaction with life.,"THE BENEFITS OF FACEBOOK “FRIENDS”

In a study by Lampe, Ellison and Steinfeld (2007) the relationship between... ","H4a: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's self esteem. H4b: The relationship between intensity of Facebook use and bonding social capital will vary depending on the degree of a person's satisfaction with life. Particularly significant changes in social networks may affect one's social capital, as when a person moves from the geographic location in which their network was formed and thus loses access to those social resources.","[3.0, 1.0, 4.0, 4.0, 3.0]",Computer_Science,train,3.0,tweets,217942795816681472
10.1038/s41598-019-40888-w,Computer_Science_tweet_45,"Visualizing heterogeneity in blood flow &amp; oxygen in capillaries throughout a tumor - work by Spyros Stamatelos, Akanksha Bhargava, Eugene Kim, Aleksander Popel &amp; Arvind Pathak #angiogenesis #imaging #modeling
 ",Figure 6b illustrates how one can visualize this heterogeneous hemodynamic landscape in Tumor 1 by www.nature.com/scientificreports www.nature.com/scientificreports/ mapping each vessel class onto the underlying microvascular network.,"Visualizing heterogeneity in blood flow &amp; oxygen in capillaries throughout a tumor - work by Spyros Stamatelos, Akanksha Bhargava, Eugene Kim, Aleksander Popel &amp; Arvind Pathak #angiogenesis #imaging #modeling
 ","Collectively, Class 3 vessels lack the full functionality of Class 2 vessels, yet are capable of maintaining transport better than Class 1 vessels. Figure 6b illustrates how one can visualize this heterogeneous hemodynamic landscape in Tumor 1 by www.nature.com/scientificreports www.nature.com/scientificreports/ mapping each vessel class onto the underlying microvascular network. Almost 90% of the vascular volume in this tumor was accounted for by Class 1 vessels that were poorly or minimally perfused, hypoxic and also exhibited the smallest median diameter among all vascular classes (Fig.","[3.0, 4.0, 2.0, 4.0]",Computer_Science,train,3.25,tweets,1111426856429862912
10.1016/j.neuroimage.2018.06.031,Computer_Science_tweet_46,EEG resting state study with cannabis users and non-users. Increased cortical activity and connectivity in users. ,A decrease in posterior network degree and an increase in the clustering coefficient in frontal regions suggests changes in long-range communications that allow for corticocortical interactions between networks and may be related to cognitive impairments associated with cannabis use.,EEG resting state study with cannabis users and non-users. Increased cortical activity and connectivity in users. ,"This loss of neural refinement indicates a noisy brain and an impairment in inhibiting ongoing neural activity that may interrupt cognitive processing. A decrease in posterior network degree and an increase in the clustering coefficient in frontal regions suggests changes in long-range communications that allow for corticocortical interactions between networks and may be related to cognitive impairments associated with cannabis use. Significant correlations were found between cannabis use measures and spectral power and functional connectivity, highlighting electrophysiological signals as relevant neural associations that may be essential in examining effects related to cannabis use.","[4.0, 4.0, 1.0, 4.0, 3.0]",Computer_Science,train,3.2,tweets,1007193937931579393
10.1126/science.aav8911,Computer_Science_tweet_47,"New dorsal/ventral distinction in macaque medial PFC - DMFC signals errors, and ACC integrates errors to drive task switches. Very nice work showing causal relationship, organizes a lot of literature  @username ","In particular, our results suggest that the long latency signals in ACC result from an integration of early error-related modulations in DMFC, much like what is seen in well-established first-order perceptual decision-making tasks between sensory and higher-order association and premotor areas ).","New dorsal/ventral distinction in macaque medial PFC - DMFC signals errors, and ACC integrates errors to drive task switches. Very nice work showing causal relationship, organizes a lot of literature  @username ","This result, coupled with an experiment involving simultaneous DMFC perturbation and ACC recording, enabled us to reveal the sequential nature of computations in DMFC and ACC and provided a coherent explanation of their distinct functional link to behavior, their different activation latencies, and their circuit-level interactions. In particular, our results suggest that the long latency signals in ACC result from an integration of early error-related modulations in DMFC, much like what is seen in well-established first-order perceptual decision-making tasks between sensory and higher-order association and premotor areas ). An important outstanding question that our study motivates is the problem of maintaining a desired behavioral strategy between switches, which may involve other brain areas such as the dorsolateral prefrontal cortex .","[5.0, 4.0, 4.0]",Computer_Science,train,4.333333333333333,tweets,1129135034412208130
10.1177/1461444816660784,Computer_Science_tweet_48,"New article on Zuckerberg's discursive construction of #Facebook &amp; users, by @username @username and myself ","Zuckerberg suggests that Facebook helps put users in contact with the communities around them, both physical and online:","New article on Zuckerberg's discursive construction of #Facebook &amp; users, by @username @username and myself ","Despite attempts to move from a US-centric college-based user to a global conception of the user, then, Zuckerberg's descriptions of site profiles still reflect a normative idea typical of certain kinds of individuals in affluent liberal societies-an idea further reinforced by Zuckerberg's depiction of himself as the prototypical Facebook user (ZF2009g). Zuckerberg suggests that Facebook helps put users in contact with the communities around them, both physical and online: (ZF2009d) It's been amazing to see how all of you have used our tools to build a real community.","[3.0, 5.0, 1.0]",Computer_Science,train,1.0,tweets,759011778944638976
10.1145/2493432.2493486,Computer_Science_tweet_49,printed circuits using a regular inkjet + silver ink: ,"Using instant inkjet circuits in the classroom it would be possible to introduce students to basic electronics principles very cheaply, and coupled with the use of anisotropic self-adhesive tape a range of electronic components could be used to augment the experience.",printed circuits using a regular inkjet + silver ink: ,"Not only could cheap sensors like this be useful in a UbiComp setting, but they could also be valuable for education. Using instant inkjet circuits in the classroom it would be possible to introduce students to basic electronics principles very cheaply, and coupled with the use of anisotropic self-adhesive tape a range of electronic components could be used to augment the experience. Ultimately it might be possible to adopt a solderless modular electronics platform like .NET Gadgeteer to use an inkjet printed substrate for interconnect instead of individual cables.","[2.0, 3.0, 5.0, 4.0, 2.0]",Computer_Science,train,3.2,tweets,400314644583047168
10.1126/scirobotics.aat4440,Computer_Science_tweet_51,Biohybrid robots are attracting attention as promising candidates to enhance robot applicability to studies on biological designs and in vitro construction of biological dynamic systems. Rapid progress in biohybrid... ,"Consequently, it is difficult to achieve compatibility between large actuation and a long lifetime in a biohybrid robot.",Biohybrid robots are attracting attention as promising candidates to enhance robot applicability to studies on biological designs and in vitro construction of biological dynamic systems. Rapid progress in biohybrid... ,"Thus, such a configuration is not suitable as a biohybrid actuator. Consequently, it is difficult to achieve compatibility between large actuation and a long lifetime in a biohybrid robot. The selective contractions of each skeletal muscle allow large actuation, and balancing the tension using antagonistic muscles prevents their spontaneous shrinkage over the long term.","[3.0, 4.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.4,tweets,1001890682846498821
10.1287/mnsc.2016.2500,Computer_Science_tweet_53,"Do checked bag charges cause delays b/o more carry-on luggage? No, airlines *improve* on-time departure performance! ","In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags.","Do checked bag charges cause delays b/o more carry-on luggage? No, airlines *improve* on-time departure performance! ","We have an indication that this occurred at some level as our results support the argument that after initially observing little performance decline, the airlines felt the need to shorten their scheduled block times. In hindsight, however, this may not have been the right decision given the performance deterioration observed after they began charging for the two checked bags. Increased boarding times as a result of baggage fees have financial implications as well.","[4.0, 2.0, 1.0, 1.0, 3.0]",Computer_Science,train,2.2,tweets,922351261906808833
10.1016/j.robot.2015.01.003,Computer_Science_tweet_57,Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) ,Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent.,Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) ,"Thus, Poincaré [41] suggested that spatial knowledge emerges from the agent's capacity to move, with spatial relations such as the distance to an object being internally encoded as potential motor commands. Philipona and co-authors showed in that under certain conditions the dimensionality of space can be estimated by analyzing only sensorimotor information that is available to the agent. Knowing the number of spatial dimensions is not, however, the same as having the notion of space.","[3.0, 2.0, 3.0, 4.0, 2.0]",Computer_Science,train,2.8,tweets,1048009477679718401
10.1088/1741-2552/aabc9b,Computer_Science_tweet_58,"""In short term in-clinic testing, energy savings were substantial (38%–45%), and therapeutic efficacy [of DBS] was maintained.""

This is a BIG DEAL. Battery drain is associated with worsening symptoms in DSB.

Longer battery life = better quality of life.

",Significance-This is the first demonstration of adaptive DBS in Parkinson's disease using a fully implanted device and neural sensing.,"""In short term in-clinic testing, energy savings were substantial (38%–45%), and therapeutic efficacy [of DBS] was maintained.""

This is a BIG DEAL. Battery drain is associated with worsening symptoms in DSB.

Longer battery life = better quality of life.

","In short term in-clinic testing, energy savings were substantial (38-45%), and therapeutic efficacy was maintained. Significance-This is the first demonstration of adaptive DBS in Parkinson's disease using a fully implanted device and neural sensing. Our approach is distinct from other strategies utilizing basal ganglia signals for feedback control.","[3.0, 3.0, 4.0, 4.0]",Computer_Science,train,3.5,tweets,994265184700059648
10.1111/jcc4.12109,Computer_Science_tweet_59,"only iPhone? or other smartphones too?

iPhone separation linked to physiological anxiety, poor cognitive performance
","In contrast, when participants completed word-search puzzles with their iPhone in their possession, heart rate and blood pressure levels returned to baseline and cognitive performance increased.","only iPhone? or other smartphones too?

iPhone separation linked to physiological anxiety, poor cognitive performance
","It is interesting to note that self-reported feelings of unpleasantness and anxiety reflected participants' physiological responses such that perceived levels of unpleasantness and anxiety were greatest during iPhone separation. In contrast, when participants completed word-search puzzles with their iPhone in their possession, heart rate and blood pressure levels returned to baseline and cognitive performance increased. Again, self-reported feelings of unpleasantness and anxiety reflected participants' physiological responses such that perceived levels of unpleasantness and anxiety were lowest when participants were in possession of their iPhone.","[4.0, 4.0, 3.0, 2.0]",Computer_Science,train,3.25,tweets,553365906819014656
10.1126/sciadv.aat7422,Computer_Science_tweet_6,"Core #language skill in typically and atypically developing #children, including those with #autism spectrum disorders, is stable from infancy to adolescence. This suggests that when a child’s language skills are lagging, early intervention is best @username  ","With respect to the four challenges posed at the outset, clear evidence emerged for individual variation in a core language skill at each of 11 ages, for convergence of multiple indices of language at each age on latent variables representing a core language skill, for the homotypic and heterotypic stability of core language skill over the long term, and for the robustness of long-term stability of core language skill in atypically developing children with several different types of health risk.","Core #language skill in typically and atypically developing #children, including those with #autism spectrum disorders, is stable from infancy to adolescence. This suggests that when a child’s language skills are lagging, early intervention is best @username  ","Individual differences tell us about the distribution of language skill, and their stability tells us about the nature and ontogeny of that language skill. With respect to the four challenges posed at the outset, clear evidence emerged for individual variation in a core language skill at each of 11 ages, for convergence of multiple indices of language at each age on latent variables representing a core language skill, for the homotypic and heterotypic stability of core language skill over the long term, and for the robustness of long-term stability of core language skill in atypically developing children with several different types of health risk. Thus, a consistent personological characteristic, experience, or environment can carry stability.","[4.0, 5.0, 2.0, 2.0, 4.0]",Computer_Science,train,4.0,tweets,1065651199884632064
10.1140/epjb/e2018-90532-7,Computer_Science_tweet_60,"The Wikipedia Ranking of World Universities (WRWU) “based on analysis of networks of 24 Wikipedia editions, [helps] determine interactions between leading universities on a scale of ten centuries” —Coquidé et al. (2018) 

 ","The largest number of top universities is in US but we see a significant numbers also for India, Japan, Germany and France for PageRank which characterizes the university influence.","The Wikipedia Ranking of World Universities (WRWU) “based on analysis of networks of 24 Wikipedia editions, [helps] determine interactions between leading universities on a scale of ten centuries” —Coquidé et al. (2018) 

 ","In total for all 24 editions we find 1011 and 1464 different universities with PageRank and CheiRank algorithms respectively. The largest number of top universities is in US but we see a significant numbers also for India, Japan, Germany and France for PageRank which characterizes the university influence. The communicativity is highlighted by CheiRank with top countries being US, India, Japan, France and China.","[1.0, 1.0, 2.0, 2.0, 3.0]",Computer_Science,train,1.8,tweets,1038453890256056321
10.1016/j.neuroimage.2013.10.028,Computer_Science_tweet_61,"""Subjects [can modulate their neural activity with practice]."" Florin et al (#neuroscience #philmind #cogsci) ",We found that the modulation of these predefined components of brain dynamics was reinforced by real-time visual feedback to subjects and is specific of targeted brain regions.,"""Subjects [can modulate their neural activity with practice]."" Florin et al (#neuroscience #philmind #cogsci) ","The targeting of pre-selected brain regions and the training of specific fast components of time-resolved brain activity within these regions is possible with real-time MEG-imaging neurofeedback. We found that the modulation of these predefined components of brain dynamics was reinforced by real-time visual feedback to subjects and is specific of targeted brain regions. Overall, this study opens new perspectives in the development of new therapeutic strategies based on real-time neurofeedback training, with direct access to the broadest range of neural dynamics, known to be affected by most neurological and neuropsychiatric conditions .","[1.0, 1.0, 2.0]",Computer_Science,train,1.3333333333333333,tweets,432897787592986625
10.1038/srep07236,Computer_Science_tweet_63,Nice! RT @username: our new paper: Predicting Node Degree Centrality w/ Node Prominence Profile  #networks #bigdata,The empirical experiments reveal that NPP is able to provide more precise prediction of node's future degree centrality over baseline solutions.,Nice! RT @username: our new paper: Predicting Node Degree Centrality w/ Node Prominence Profile  #networks #bigdata,"Triad 3 is a stable sub-structure , as the propensity of attaching new links for the nodes having high occurrence frequencies in position 5 is relatively small. The empirical experiments reveal that NPP is able to provide more precise prediction of node's future degree centrality over baseline solutions. NPP is validated on four different social networks.","[2.0, 3.0, 3.0, 3.0]",Computer_Science,train,2.75,tweets,539581438362783745
10.1038/nature12966,Computer_Science_tweet_65,Computational design of vaccine antigens based on epitope scaffolds with backbone flexibility.  #NBTHighlight,"Although 17-HD9 and mota bury a similar amount of area on the epitope (690 Å 2 versus 683 Å 2 ), 17-HD9 uses a different paratope to make more hydrogen bonds (15-18 versus 7) that plausibly contribute to its higher scaffold affinity and higher neutralization potency ( Fig.",Computational design of vaccine antigens based on epitope scaffolds with backbone flexibility.  #NBTHighlight,"The , and 85% of the epitope residues buried by either mota or 17-HD9 are also buried by the other ( Fig. Although 17-HD9 and mota bury a similar amount of area on the epitope (690 Å 2 versus 683 Å 2 ), 17-HD9 uses a different paratope to make more hydrogen bonds (15-18 versus 7) that plausibly contribute to its higher scaffold affinity and higher neutralization potency ( Fig. The 17-HD9 complexes are also consistent with the ability of 17-HD9 to bind to the K82E mota escape mutant: density for the K82 side chain is absent in two out of four 17-HD9 complexes, and K82 is only 37% buried by 17-HD9 in the other two complexes (Fig.","[1.0, 3.0, 2.0, 3.0, 2.0]",Computer_Science,train,2.2,tweets,431517912306704384
10.1177/1529100615569721,Computer_Science_tweet_67,"Putting ""Education"" in Educational Apps: Lessons from the Science of Learning  #edu #parenting #edtech #openaccess",We must find ways to help parents assess apps that exist in this first wave .,"Putting ""Education"" in Educational Apps: Lessons from the Science of Learning  #edu #parenting #edtech #openaccess","While this may sound encouraging to app developers and users, little detail was offered about the study design, making it difficult to evaluate its scientific impact. We must find ways to help parents assess apps that exist in this first wave . While there is no way to scientifically study every app on the market, a set of principles based on science can be developed and used to evaluate the current crop of apps.","[1.0, 2.0, 1.0, 3.0]",Computer_Science,train,1.75,tweets,590311604094312448
10.1177/1080569913501862,Computer_Science_tweet_68,"When you access your phone in a meeting it shows: Lack of attention, listening, power, respect, self-awareness and social awareness #research ","Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings.","When you access your phone in a meeting it shows: Lack of attention, listening, power, respect, self-awareness and social awareness #research ","Also, higher-income professionals showed lower acceptance for mobile phone use during meetings. Finally, professionals in the Western region of the United States were less accepting of mobile phone use during meetings. In the informal meeting setting (see Model 2 in Table 5 ), the following variables were significant predictors: age, gender, and region.","[1.0, 5.0, 2.0, 3.0]",Computer_Science,train,2.0,tweets,978552838803673089
10.1016/j.robot.2015.01.003,Computer_Science_tweet_69,Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) ,"In some sense, the sensory manifold S describes the agent's internal experience of its translation in space, and is the only information it can gather about space.",Learning agent's spatial configuration from sensorimotor invariants. (arXiv:1810.01872v1 [cs.LG]) ,"This result was expected, as the dimensionality of the manifold S is determined by the number of degrees of freedom during exploration . In some sense, the sensory manifold S describes the agent's internal experience of its translation in space, and is the only information it can gather about space. However, S depends dramatically on the environment: the same exploratory movements performed in a different environment E will yield another sensory manifold S , which is totally different from S (see Fig.","[4.0, 1.0, 2.0, 2.0]",Computer_Science,train,2.25,tweets,1048084628341325824
10.1126/scirobotics.aat5999,Computer_Science_tweet_7,"Guided by a #robot named Minnie, early adolescent children were more engaged in reading activities and motivated to #read during #summerbreak, found @username @username researchers:  ","In summary, our social robot, Minnie, demonstrates the potential for transforming reading at home from an isolated activity into a social and collaborative experience that can promote comprehension and interest in reading.","Guided by a #robot named Minnie, early adolescent children were more engaged in reading activities and motivated to #read during #summerbreak, found @username @username researchers:  ","Although these deliberate technical simplifications produced a fairly robust system, enabling extended maintenance-free use in the field, improving the core technology and the interactivity of the social robot platform will offer a more seamless user experience. In summary, our social robot, Minnie, demonstrates the potential for transforming reading at home from an isolated activity into a social and collaborative experience that can promote comprehension and interest in reading. Our results illuminate how we might maximize the societal benefits of imminent robotic technology and demonstrate how the integration of social robots into an existing human activity can transform human experience toward this good.","[4.0, 3.0, 4.0]",Computer_Science,train,3.6666666666666665,tweets,1032637080348880897
10.1098/rstb.2008.0288,Computer_Science_tweet_70,"@username It was a nightmare recruiting MRI-compatible retired London taxi drivers. 
Here's the article: ","Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ).","@username It was a nightmare recruiting MRI-compatible retired London taxi drivers. 
Here's the article: ","In comparison with the posterior hippocampus that had greater grey matter volume compared with control participants, the anterior hippocampus had reduced grey matter volume in taxi drivers (Maguire et al. Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ). We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume.","[1.0, 2.0, 3.0]",Computer_Science,train,2.0,tweets,1037726320409620481
10.1088/1741-2552/aabc9b,Computer_Science_tweet_71,"@username &amp; @username researchers propose an interesting adaptive approach to improving deep brain stimulation for #Parkinsons using motor cortex sensing
 ","We have demonstrated the feasibility of adaptive DBS in PD using a fully implantable device, with feedback control provided by a cortical gamma band oscillation related to the emergence of dyskinesia, a common adverse effect of levodopa therapy and of STN DBS.","@username &amp; @username researchers propose an interesting adaptive approach to improving deep brain stimulation for #Parkinsons using motor cortex sensing
 ","The zoomed in views of state changes in Figures 3c and 4b indicate that changes in classifier state were appropriately triggered by changes in gamma power. We have demonstrated the feasibility of adaptive DBS in PD using a fully implantable device, with feedback control provided by a cortical gamma band oscillation related to the emergence of dyskinesia, a common adverse effect of levodopa therapy and of STN DBS. While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches.","[4.0, 3.0, 5.0, 2.0]",Computer_Science,train,3.5,tweets,994524357727850496
10.1126/science.aaf2654,Computer_Science_tweet_72,Are we ready for utilitarian cars? Interesting paper on ethical dilemmas presented by autonomous cars: ,"Once more, it appears that people praise utilitarian, self-sacrificing AVs, and welcome them on the road, without actually wanting to buy one for themselves.",Are we ready for utilitarian cars? Interesting paper on ethical dilemmas presented by autonomous cars: ,"But in terms of purchase intention, it received significantly fewer points than the high-valued algorithm (p < 0.001), and was in fact closer to the low-valued algorithms (median budget share = 33). Once more, it appears that people praise utilitarian, self-sacrificing AVs, and welcome them on the road, without actually wanting to buy one for themselves. This is the classic signature of a social dilemma, in which everyone has a temptation to free-ride instead of adopting the behavior that would lead to the best global outcome.","[4.0, 3.0, 2.0, 4.0, 3.0]",Computer_Science,train,3.2,tweets,657254478911922176
10.1016/j.neuroimage.2014.12.086,Computer_Science_tweet_73,How neural representations change during physics instruction  &amp; correlate w/other concepts ,"In the case of the instructional materials used here, the neural knowledge representations evolved through distinct states, including an initial state before instruction and three additional states following three types of instruction.",How neural representations change during physics instruction  &amp; correlate w/other concepts ,"Furthermore, the similarity relations among the neural representations of different systems are driven in part by the similarities among the system descriptions. In the case of the instructional materials used here, the neural knowledge representations evolved through distinct states, including an initial state before instruction and three additional states following three types of instruction. The brain locations that responded consistently to the items during test (thinking) trials (as well as the activation locations during explanation trials) provided evidence for the following states of the representation of knowledge: 0.","[3.0, 4.0, 3.0]",Computer_Science,train,3.333333333333333,tweets,731930440550866944
10.1038/s41598-018-27405-1,Computer_Science_tweet_74,New paper out today - a potential mechanism for cultural transmission of tool designs by New  Caledonian crows ,"Prior to the emergence of stone tools, it is likely that hominin tool behaviour involved a greater proportion of cognitively transparent behaviours , and emulative processes may have played an important role in their transmission .",New paper out today - a potential mechanism for cultural transmission of tool designs by New  Caledonian crows ,"Here, emulation could be sufficient to enable cultural transmission and evolution. Prior to the emergence of stone tools, it is likely that hominin tool behaviour involved a greater proportion of cognitively transparent behaviours , and emulative processes may have played an important role in their transmission . These findings also raise the possibility that other cases of transparent tool manufacture, such as the varied fishing probes manufactured by chimpanzees 50 , could potentially allow for cumulative cultural evolution.","[1.0, 2.0, 2.0, 3.0]",Computer_Science,train,2.0,tweets,1012358399357521922
10.1038/nature12311,Computer_Science_tweet_75,A compendium of #RNA-binding motifs for decoding gene regulation: #RNA-binding proteins are key...  #nature #npg,"Moreover, we can associate them with distinct functional roles in diverse types of post-transcriptional regulation, enabling new insights into the functions of RNA-binding proteins both in normal physiology and in human disease.",A compendium of #RNA-binding motifs for decoding gene regulation: #RNA-binding proteins are key...  #nature #npg,"The motifs that we identify in vitro correlate well with in vivo RNA-binding data. Moreover, we can associate them with distinct functional roles in diverse types of post-transcriptional regulation, enabling new insights into the functions of RNA-binding proteins both in normal physiology and in human disease. These data provide an unprecedented overview of RNA-binding proteins and their targets, and constitute an invaluable resource for determining post-transcriptional regulatory mechanisms in eukaryotes.","[2.0, 3.0, 4.0]",Computer_Science,train,3.0,tweets,355023777781911552
10.1073/pnas.1510619112,Computer_Science_tweet_76,"Investigate the modular functional architecture of the human brain across 9,208 experiments and 77 cognitive tasks ","Moreover, there is a strong spatial correspondence between modules derived from spontaneous neural activity obtained with rs-fMRI and the task-evoked activity in the BrainMap database, and these modules can be linked to broad behavioral domains or to specific groups of related tasks , suggesting that these modules might be dedicated to discrete cognitive functions.","Investigate the modular functional architecture of the human brain across 9,208 experiments and 77 cognitive tasks ","As mentioned in the Introduction, the genetic basis of each module is significantly specialized, a necessary condition for each module to have a discrete function that was shaped modularly by natural selection (3). Moreover, there is a strong spatial correspondence between modules derived from spontaneous neural activity obtained with rs-fMRI and the task-evoked activity in the BrainMap database, and these modules can be linked to broad behavioral domains or to specific groups of related tasks , suggesting that these modules might be dedicated to discrete cognitive functions. However, these analyses did not empirically derive discrete cognitive functions from the data in BrainMap that could be linked to specific regions in the brain.","[1.0, 3.0, 2.0, 4.0]",Computer_Science,train,2.5,tweets,670197112882204672
10.1534/genetics.118.301267,Computer_Science_tweet_77,"New constructed genomic predictors explain, respectively, ∼40, 20, and 9 percent of total variance for height, heel bone density, and educational attainment ",The SNP heritability of the molecular markers used to build the predictor can be interpreted as an upper bound to the variance that could be captured by the predictor.,"New constructed genomic predictors explain, respectively, ∼40, 20, and 9 percent of total variance for height, heel bone density, and educational attainment ","However, the total variance accounted for by these SNPs is still a small fraction of the trait heritability and of the proportion of variance that could be captured by regression on common SNPs as suggested by SNP heritability estimates . The SNP heritability of the molecular markers used to build the predictor can be interpreted as an upper bound to the variance that could be captured by the predictor. While identification of GWAS SNPs is accomplished by single SNP regression, construction of a best predictor is a global optimization problem in the high dimensional space of possible effect sizes of all SNPs.","[2.0, 2.0, 1.0, 1.0]",Computer_Science,train,1.5,tweets,1035175920619929603
10.5772/58730,Computer_Science_tweet_78,"How many #swarm #robot platforms can you enumerate?
Kilobot, s-bot, Alice, Jasmine, ...

Do you know these?

Colias

a Hexbug Spider

or MONSUN II?


read about it here soon:
","In comparison to the other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform (about £25) and hence it is feasible for the easy and economic replication of large numbers of robots.","How many #swarm #robot platforms can you enumerate?
Kilobot, s-bot, Alice, Jasmine, ...

Do you know these?

Colias

a Hexbug Spider

or MONSUN II?


read about it here soon:
","The design of Colias was considered in terms of these requirements and, due to its small size and fast motion, experiments could be conducted both cost-and time-effectively in a small working area. In comparison to the other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform (about £25) and hence it is feasible for the easy and economic replication of large numbers of robots. The parallel processing provides for the fast and reliable control of different functions of the robot.","[3.0, 4.0, 2.0, 3.0]",Computer_Science,train,3.0,tweets,950744361159061509
10.1038/nature12112,Computer_Science_tweet_79,Here's the journal paper on location memories encoded in flexible #hippocampus cell configurations  #brain #memory,"Thus, animals were required to learn a new goal location, demanding a flexible behavioural response that was more likely to engage the hippocampus than a fixed reference-memory response 31 .",Here's the journal paper on location memories encoded in flexible #hippocampus cell configurations  #brain #memory,"First, because the shortest routes in phase one and two were matched, it was determined that animals could remember Home, but could not detect Random locations, because latencies and path lengths were significantly shorter for Home-bound trajectories ( Fig. Thus, animals were required to learn a new goal location, demanding a flexible behavioural response that was more likely to engage the hippocampus than a fixed reference-memory response 31 . Hence during this period, every Home-bound trajectory was always a novel combination of current location and goal location.","[4.0, 2.0, 1.0, 4.0, 2.0]",Computer_Science,train,2.0,tweets,324955045764399104
10.1287/mnsc.2016.2500,Computer_Science_tweet_8,"@username @username ignoring customer loyalty, this 2013 paper finds that charging a fee for one checked bag correlates with improved on-time departure performance

abstract 
pdf  ","We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.","@username @username ignoring customer loyalty, this 2013 paper finds that charging a fee for one checked bag correlates with improved on-time departure performance

abstract 
pdf  ","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period. When grouped into 'low-cost' versus 'legacy' carriers, however, we find opposite effects: the departure performance of the low-cost airlines became worse while it improved for the legacy carriers.","[5.0, 5.0, 5.0, 3.0]",Computer_Science,train,4.5,tweets,1098819528752914432
10.1126/scirobotics.aar4423,Computer_Science_tweet_81,"Bacteria-propelled biohybrid microswimmers have recently shown to be able to actively transport and deliver cargos encapsulated into their synthetic constructs to specific regions locally. However, usage of synthetic... ","Moreover, the RBC microswimmers preserved their integrity when deformed inside the microchannels and collected at the outlet (Fig.","Bacteria-propelled biohybrid microswimmers have recently shown to be able to actively transport and deliver cargos encapsulated into their synthetic constructs to specific regions locally. However, usage of synthetic... ","RBC microswimmers were able to deform inside the microchannels and pass through with ease (Fig. Moreover, the RBC microswimmers preserved their integrity when deformed inside the microchannels and collected at the outlet (Fig. The percentage of RBC microswimmers before injection (fabrication yield, ~72% of the total RBC population) did not decrease significantly (twotailed t test, P > 0.05) after squeezing through the microchannels (~50%) (Fig.","[5.0, 4.0, 1.0, 3.0, 4.0]",Computer_Science,train,3.0,tweets,989225423790784512
10.1016/j.neuroimage.2014.02.004,Computer_Science_tweet_82,Neurocinematics: Intersubject consistency of cortical MEG signals during movie watching ,"Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie .",Neurocinematics: Intersubject consistency of cortical MEG signals during movie watching ,"These findings demonstrate the capability of the proposed methodology to uncover cortical MEG signatures from single-trial signals that are consistent across spectators of a movie. Differences in synchronous activity likely reflect timelocking of the brain areas to stimulus features, as well as to actual content and events in the movie . Emotional video clips, compared with non-emotional ones, increase intersubject synchronization of voxel-wise fMRI time courses in many brain areas, for example in the dorsal attention network .","[1.0, 2.0, 2.0, 4.0]",Computer_Science,train,2.25,tweets,453074756259303424
10.1016/j.neuroimage.2015.05.038,Computer_Science_tweet_84,The understanding of empathy from a neuroscientific perspective: Emotions and Rationality in terms of gray matter ,This highlights a consistent neural substrate for each component of empathy.,The understanding of empathy from a neuroscientific perspective: Emotions and Rationality in terms of gray matter ,"showed that the affective component of empathy was more associated with insula activity, whereas the cognitive component of empathy was more associated with the midcingulate cortex and adjacent dorsomedial prefrontal cortex (MCC/dmPFC). This highlights a consistent neural substrate for each component of empathy. Considering our aims, peak MNI coordinates for affective (i.e., insula) and cognitive .","[3.0, 3.0, 4.0, 2.0]",Computer_Science,train,3.0,tweets,613604030904958976
10.1038/s42256-018-0015-y,Computer_Science_tweet_85,"Whetstone: A Method for Training Deep Artificial Neural Networks for Binary Communication. William Severa, Craig M. Vineyard, Ryan Dellana, Stephen J. Verzi, and James B. Aimone ","As GPUs and and other architectures increasingly pursue the ability to perform sparse computations efficiently, the resulting binary communication from the Whetstone method is well suited for such approaches.","Whetstone: A Method for Training Deep Artificial Neural Networks for Binary Communication. William Severa, Craig M. Vineyard, Ryan Dellana, Stephen J. Verzi, and James B. Aimone ","Not only does the Whetstone method offer a means to make use of emerging low power neuromorphic hardware, but it may be beneficial for other accelerators as well. As GPUs and and other architectures increasingly pursue the ability to perform sparse computations efficiently, the resulting binary communication from the Whetstone method is well suited for such approaches. For example, if an architecture can replace multiplications with signed addition the binarization of the communication by the Whestone method converts an ANN to a suitable representation.","[1.0, 3.0, 5.0]",Computer_Science,train,3.0,tweets,1057087347144212480
10.1073/pnas.1419704112,Computer_Science_tweet_86,"""Rate of language evolution and population size [Evolution]"" ","Our analysis provides, to our knowledge, the first statistically robust evidence of an influence of population size on rate of language change.","""Rate of language evolution and population size [Evolution]"" ","Here, we use data from closely related pairs of languages to show that a key prediction of evolutionary theory is met: rates of gain of new words are higher in larger populations whereas rates of word loss are greater in small populations. Our analysis provides, to our knowledge, the first statistically robust evidence of an influence of population size on rate of language change. These results demonstrate the potential for demographic factors to influence language evolution.","[3.0, 3.0, 3.0, 4.0]",Computer_Science,train,3.25,tweets,567827886549299200
10.1007/s10055-018-0346-3,Computer_Science_tweet_88,"@username @username @username Wondering if that could also help me with memory palaces  and  making them ""scalable"" 🤔",Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.,"@username @username @username Wondering if that could also help me with memory palaces  and  making them ""scalable"" 🤔","If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups. Much as textbooks and videos are used today for knowledge dissemination, it could be possible for virtual memory palaces to be used one day for effective transfer of mnemonic devices among humans in virtual environments.","[1.0, 1.0, 2.0, 4.0]",Computer_Science,train,1.0,tweets,1160123244801904640
10.1126/science.aaf2654,Computer_Science_tweet_9,"The Ethics of Autonomous Vehicles, ""whether an AV should save lives by sacrificing its owner"": ",Defining the algorithms that will help AVs make these moral decisions is a formidable challenge.,"The Ethics of Autonomous Vehicles, ""whether an AV should save lives by sacrificing its owner"": ","Defining the algorithms that will help AVs make these moral decisions is a formidable challenge. We found that participants to six MTurk studies approved of utilitarian AVs (that sacrifice their passengers for the greater good), and would like others to buy them; but they would themselves prefer to ride in AVs that protect their passengers at all costs. They would disapprove of enforcing utilitarian AVs, and would be less willing to buy such a regulated AV.","[3.0, 2.0, 4.0, 4.0]",Computer_Science,train,3.25,tweets,655827913154019330
10.1073/pnas.1814646116,Computer_Science_tweet_91,"Computer science skills across 4 countries

@username #openaccess 
The US leads China, India and Russia among graduating seniors (for now)
#AI ","The within-country gender gaps in CS skills, while significant, are generally smaller than the skill gaps between the United States and other countries as well as between elite and nonelite programs.","Computer science skills across 4 countries

@username #openaccess 
The US leads China, India and Russia among graduating seniors (for now)
#AI ","Males score 0.15 SDs higher than females in China (P = 0.093), 0.24 SDs higher in India (P = 0.077), 0.25 SDs higher in Russia (0.022), and 0.41 SDs higher in the United States (P = 0.000). The within-country gender gaps in CS skills, while significant, are generally smaller than the skill gaps between the United States and other countries as well as between elite and nonelite programs. Females in the United States score 0.35-0.42 SDs higher than males in China, India, or Russia (P = 0.000) and 0.52-0.67 SDs higher than females in China, India, or Russia (P = 0.000).","[2.0, 2.0, 3.0, 5.0]",Computer_Science,train,1.0,tweets,1107823697274888192
10.1126/scirobotics.aat3818,Computer_Science_tweet_92,Our paper on a multilayered e-dermis for detecting pain in a prosthesis is out now in @username.  ,"As expected, the epidermal layer was the most activated taxel during loading and absorbed the largest pressure.",Our paper on a multilayered e-dermis for detecting pain in a prosthesis is out now in @username.  ,"The response of the fingertip taxels during object loading captured differences in object curvature based on the relative activation of all sensing elements (Fig. As expected, the epidermal layer was the most activated taxel during loading and absorbed the largest pressure. The sharp edge of object 3 produced a highly localized pressure source on the epidermal layer of the e-dermis, which triggered the neuromorphic nociceptor model (see Materials and Methods) (Fig.","[1.0, 1.0, 4.0, 2.0, 5.0]",Computer_Science,train,1.0,tweets,1009503801672421379
10.1073/pnas.1800923115,Computer_Science_tweet_93,Zebrafish swimming in groups at high Reynolds number learn how to intercept the wakes produced by the others. Computer simulations combining hydrodynamics and neural networks ,"In the early stages of training (first 10000 transitions -green bars), the swimmer does not show a strong preference for maintaining any particular separation distance.",Zebrafish swimming in groups at high Reynolds number learn how to intercept the wakes produced by the others. Computer simulations combining hydrodynamics and neural networks ,"The smart-follower is capable of adapting to deviations in the leader's trajectory (Supplementary Movie S3), as these situations are encountered when performing random actions during training. In the early stages of training (first 10000 transitions -green bars), the swimmer does not show a strong preference for maintaining any particular separation distance. Towards the end of training (last 10000 transitions -lilac bars), the swimmer displays a strong preference for maintaining a separation-distance of either ∆x = 1.5L or 2.2L.","[1.0, 5.0, 1.0, 3.0]",Computer_Science,train,1.0,tweets,999154349707268096
10.1145/2733373.2809930,Computer_Science_tweet_94,Methods and implications of machine vision understanding fashion trends ,"For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, gray and black colors.",Methods and implications of machine vision understanding fashion trends ,"We observe that there are always some classic colors, patterns or styles that have a large amount of clothing images in the fashion shows of every year. For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, gray and black colors. These examples indicate that the results generated by attribute description methods are very reasonable and these results can be a very significant reflection for the fashion shows styles.","[2.0, 1.0, 5.0]",Computer_Science,train,1.0,tweets,640582184428945409
10.1016/j.ijgfs.2011.11.002,Computer_Science_tweet_95,A review of #souvide cooking from the International Journal of Gastronomy and Food Science: ,Note that found that fish cooked sous vide retains more healthful omega-3 fatty acids and nutrients than traditionally cooked fish.,A review of #souvide cooking from the International Journal of Gastronomy and Food Science: ,"• C/ 38 Note that found that fish cooked sous vide retains more healthful omega-3 fatty acids and nutrients than traditionally cooked fish. Sous vide cooked vegetables, in comparison, retain nearly all their nutritive value ).","[1.0, 3.0, 3.0]",Computer_Science,train,2.333333333333333,tweets,949763760784207872
10.1126/scirobotics.aaq0899,Computer_Science_tweet_97,To celebrate the last day of #NationalRoboticsWeek -- #humanoids from @username perform physical activity akin to a human #workout. Read all about their design principles here:  ,"If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers.",To celebrate the last day of #NationalRoboticsWeek -- #humanoids from @username perform physical activity akin to a human #workout. Read all about their design principles here:  ,"An interesting application is active crash test dummies used during car crash testing, because current dummies can only measure passive behavior. If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers. Similar link lengths and mass distributions (in other words, body proportions) to humans provide similar kinematics and dynamics.","[1.0, 3.0, 2.0, 3.0]",Computer_Science,train,2.25,tweets,985490575670628352
10.1007/s10055-018-0346-3,Computer_Science_easy_0,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ).","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","Lastly, place cells in the hippocampus activate in specific spatial locations, independent of orientation, providing an internal representation of the environment . This leads us to the possibility that a spatial virtual memory palace, experienced in an immersive virtual environment, could enhance learning and recall by leveraging the integration of vestibular and proprioceptive inputs (overall sense of body position, movement, and acceleration) ). This study found that the users who used a graphics desktop environment as the basis for their method of loci performed better than those using a mental scene of their choice, and those who were not instructed on a memory strategy did not perform as well as those who were instructed to use the memory strategy.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1186/s12911-017-0526-1,Computer_Science_easy_3,"""Most stakeholders felt very strongly that the information should be available wherever the patient wants it,"" Showalter said.","Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for risk of cancer recurrence and other patient-specific factors such as age, other medical problems and lifestyle.","One major theme was that the tool should be useful both in the doctor's office, so patients can discuss care options with their physicians, and at home, so that they can compare various scenarios with their loved ones. ""Most stakeholders felt very strongly that the information should be available wherever the patient wants it,"" Showalter said. ""There should be a private web portal, there should be the ability to print and it should be available both at home, before the physician appointment, and in the doctor's office as well.","It was recommended that the decision aid format be interactive, with patients being able to iteratively adjust model inputs to see the impact on model outcomes. Stakeholders were enthusiastic about the potential value of using decision analysis modeling with personalized model inputs for risk of cancer recurrence and other patient-specific factors such as age, other medical problems and lifestyle. Table 2 displays key decision aid elements that were identified based on stakeholder engagement that will be used to design a more effective patient-centered tool.",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1145/2872427.2883081,Computer_Science_easy_4,"Also, it is a good idea to cite reputable sources and provide links to external sites, so that information is recognized as objective, rather than a biased opinion.",The high quality of argumentation makes CMV a model site for seeing whether opinion shifts can at least occur under favorable conditions.,"ADVERTISEMENT

When you engage Trump loyalists in debate, try to respond with meaty content that has greater numbers of sentences and paragraphs, since research shows that one-liners and superficial statements do little to persuade people. Also, it is a good idea to cite reputable sources and provide links to external sites, so that information is recognized as objective, rather than a biased opinion. Avoid using emotionally-charged words and approach them in a way that does not feel threatening.","These advantages are not jointly exhibited by other debate sites, such as CreateDebate.com, ForandAgainst.com, or Debate.org. The high quality of argumentation makes CMV a model site for seeing whether opinion shifts can at least occur under favorable conditions. Adequate on-topic information is.""",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1016/j.compag.2016.07.028,Computer_Science_easy_5,"Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development.","This index emphasizes the green component in RGB pixels, and minimizes the effect of nonconsistent illumination among different images .","It's a very good problem to have."" Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","This significantly lowered LWC and created a large range in LWC. This index emphasizes the green component in RGB pixels, and minimizes the effect of nonconsistent illumination among different images . The top view image was excluded from calculations of plant PA. At later developmental stages, tall plants are much closer to the top view camera, making plants to appear larger, introducing significant bias in the calculation of plant PA.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_easy_6,"In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.","However, when the users went from a HMD to a desktop, their performance surprisingly decreased.","The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","When users went from a desktop to a HMD, their performance generally improved. However, when the users went from a HMD to a desktop, their performance surprisingly decreased. When comparing each participant's first trials, the desktop-1 and HMD-1, their distribution of recall scores was not significantly different with p = 0.62 > 0.05 , but they Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/978-3-642-55220-5_1,Computer_Science_easy_7,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,This complexity is smaller than L Q (α ) for any α > α.,"Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","This yields the following result. This complexity is smaller than L Q (α ) for any α > α. Hence, for any α < 1/3, our algorithm is faster than the best previously known algorithm, namely FFS and its variants.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1287/mnsc.2016.2500,Computer_Science_easy_8,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.",average delay in the After period minus average delay in the Before period.,"Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","Because our model includes a rich set of control variables, we are able to explain about 38% of the variation in Actual-TurnAroundTime variable. average delay in the After period minus average delay in the Before period. Standard errors are shown in parantheses.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2560/13/2/026017,Computer_Science_easy_9,"Once the researchers coupled the ring and pinkie fingers together, the accuracy increased to 88 percent.","For MFCC features, we did not find evidence that phoneme time position influenced classification accuracy (b = 0.051, p = 0.225).","Initially, the mind-controlled limb had an accuracy of 76 percent. Once the researchers coupled the ring and pinkie fingers together, the accuracy increased to 88 percent. ""It makes sense that coupling these two fingers improved the accuracy.""","Here, the time position of a phoneme is equal to the amount of elapsed time between the utterance onset and the phoneme time point. For MFCC features, we did not find evidence that phoneme time position influenced classification accuracy (b = 0.051, p = 0.225). However, for averaged HGWs from subject B, the analysis revealed a significant effect in which accuracy diminished as a function of phoneme time position (b = -0.792, < -p 10 10 ).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1016/j.robot.2015.01.003,Computer_Science_easy_11,The ideas introduced by Poincare can be better explained with a simple example.,"Even if sensations s depend on the environment, the sets M s are thus environmentindependent.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","Those particular cases aside, every set M s corresponds to a certain input s but also to a certain position of the agent in space. Even if sensations s depend on the environment, the sets M s are thus environmentindependent. All the possible sets M i have a specific structure that can be captured to build an internal representation of the external agent's configuration.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1098/rspb.2019.0646,Computer_Science_easy_13,"Through these experiments, researchers showed that this choice met four criteria that indicate habituation.","They found that specialist forms evolved on the disjunct and mottled backgrounds (which had relatively large patches), while the speckled backgrounds (with small patches) produced generalists.","But, they also found that male guppies with familiar patterns became interesting again to the guppies held in isolation. Through these experiments, researchers showed that this choice met four criteria that indicate habituation. First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure.","It is also possible to find cases where the specialist and generalist strategies have similar survival rates. They found that specialist forms evolved on the disjunct and mottled backgrounds (which had relatively large patches), while the speckled backgrounds (with small patches) produced generalists. This also supports the prediction that highly similar microhabitats should favour the evolution of compromise prey, while more highly different microhabitats created by discrete patches favour specialism.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1098/rspb.2019.0646,Computer_Science_easy_16,"We've shown that this attraction to the unusual happens because of habituation, which means that females tune out repetitive information, and pay more attention to things that look different.""","Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment.","Ones with unusual color patterns stand a better chance at successfully wooing a mate. We've shown that this attraction to the unusual happens because of habituation, which means that females tune out repetitive information, and pay more attention to things that look different."" Their study is published in the Proceedings of the Royal Society B.

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The team's research builds on a study Hughes conducted several years ago that found that guppies' color patterns did seem to influence mate choice.","Optimal countershading appears to be strongly illumination dependent [61] and having suboptimal countershading seems to be almost as bad as having no countershading at all, at least in a study with highly different illumination conditions . Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment. While the study of imperfect camouflage is valuable in its own right, it also has a number of important implications for other areas of biology.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_18,"Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.","This ""adaptive DBS"" approach is promising but may be challenging to implement in fully implantable systems due to the small amplitude of the STN LFP coupled with the large stimulation artifact generated when sensing a signal in close proximity to the stimulating contact.","Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","DBS could be improved by automated adjustment of stimulation in response to neural signatures of motor impairment or of stimulation-induced adverse effects. This ""adaptive DBS"" approach is promising but may be challenging to implement in fully implantable systems due to the small amplitude of the STN LFP coupled with the large stimulation artifact generated when sensing a signal in close proximity to the stimulating contact. Further, beta band phenomena are strongly affected by normal voluntary movement , which may complicate their use as signatures of motor impairment.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1287/mnsc.2016.2500,Computer_Science_easy_19,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays.","Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway. Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays. Using over 27,000 monthly route observations between 1997 to 2000, find that less competitive routes are characterized by lower service quality, in terms of both more frequent and longer flight delays.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_20,"McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor.",3.,"The chicken was still very tough; the residual taste in my mouth still very strong. McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor. McNuggets are preserved enough to sustain themselves through an apocalypse and still taste like theyare fresh out of the fryer.","Vacuum packaging doesn't reduce the microorganisms, so you must either return it to the refrigerator or freezer or (in most cases) begin cooking immediately in a temperature controlled water bath. 3. Recall that it's important that the pouches are completely submerged and not overlapping in order to heat evenly.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1177/1080569913501862,Computer_Science_easy_21,Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.,"Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive.""","Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","In an open-ended format, we got some sense of the intensity of some of these comments. Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive."" The intensity of these comments was stronger when talking about what managers do.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_22,"The hippocampus's rear section seems to be important for spatial navigation specifically, but Maguire says the front end's role remains more mysterious.","From this, we conclude that intensively acquiring a large amount of knowledge over many years is not invariably associated with structural brain differences.","She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training. The hippocampus's rear section seems to be important for spatial navigation specifically, but Maguire says the front end's role remains more mysterious. Maguire says she was ""greatly relieved"" by the results of her study, which appears in the December issue of Current Biology.","Moreover, the amount of medical experience, which ranged from 0.5 to 22.5 years, did not correlate with grey matter volume in the hippocampus or elsewhere in the brain. From this, we conclude that intensively acquiring a large amount of knowledge over many years is not invariably associated with structural brain differences. Instead, it would seem that hippocampal grey matter volume effects are more likely to be observed when the knowledge acquired concerns a complex and detailed large-scale spatial layout.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.robot.2015.01.003,Computer_Science_easy_23,The ideas introduced by Poincare can be better explained with a simple example.,"Evidently, so many years of sensorimotor experience provide an enormous amount of data to lift the curse of dimensionality.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","Spatial reasoning remains immature until the age of 6-10 years . Evidently, so many years of sensorimotor experience provide an enormous amount of data to lift the curse of dimensionality. Having a robot explore its environment for an extended period of time may thus be an inevitable cost to be paid for the autonomous emergence of such perceptual notions.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.compag.2016.07.028,Computer_Science_easy_25,The researchers already knew that water-filled plant tissues absorb different wavelengths of light - and absorb the same wavelengths differently - than do their drier counterparts.,"It should be noted that, genotype specific biases for the pixel count based method for biomass estimation, are also documented in other phenotyping studies .","We were fairly successful in doing that."" The researchers already knew that water-filled plant tissues absorb different wavelengths of light - and absorb the same wavelengths differently - than do their drier counterparts. This allowed them to build a mathematical model that hewed closely to measurements of actual water content, the study reported.","This would lead to an underestimate of shoot fresh and dry weight for FFMM-A. It should be noted that, genotype specific biases for the pixel count based method for biomass estimation, are also documented in other phenotyping studies . 4 shows the accumulation of shoot FW of 60 maize plants by genotype and water treatment at the first stage of the experiment (DAS 6 to 26).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_easy_26,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","When users went from a desktop to a HMD, their performance generally improved.","The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","10 ), but when going to the other display, the performance changed. When users went from a desktop to a HMD, their performance generally improved. However, when the users went from a HMD to a desktop, their performance surprisingly decreased.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_27,"Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results.","Cooking in heat-stable, vacuumized pouches improves shelf-life and can enhance taste and nutrition.","Still, though, I had some lingering questions about their safety. Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results. That may be so, but it isn't any more likely than with vacuum bags designed for sous vide cooking -- they are made out of the exact same kind of plastic.","Precise temperature control gives more choice over doneness and texture than traditional cooking methods. Cooking in heat-stable, vacuumized pouches improves shelf-life and can enhance taste and nutrition. Vacuum-sealing has several benefits: it allows heat to be efficiently transferred from the water (or steam) to the food; it increases the food's shelf-life by eliminating the risk of recontamination during storage; it inhibits off-flavors from oxidation and prevents evaporative losses of flavor volatiles and moisture during cooking ; and reduces aerobic bacterial growth -this results in especially flavorful and nutritious food .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.compag.2016.07.028,Computer_Science_easy_28,"In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward.","Second, new imaging protocols should be tested to minimize plants' waiting time in the head house before imaging.","But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant. In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward. Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties.","Successful testing on more maize genotypes would allow us to draw a more solid conclusion on the usefulness of hyperspectral imaging, and extend the applicability of the hyperspectral models for leaf water content prediction. Second, new imaging protocols should be tested to minimize plants' waiting time in the head house before imaging. This would make the thermal IR and steady state fluorescence imaging useful for water-stress related plant phenotyping experiments.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1177/1080569913501862,Computer_Science_easy_29,"When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age.","Several other actions were cited less frequently, including browsing the Internet, excusing oneself from a meeting to take a call, bringing a phone to a meeting, and checking the time with a phone.","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



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Those differences are still there, if less pronounced, for more formal meetings:

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Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","Roughly one fourth of employees had observed recent examples of employees checking incoming calls or allowing their phones to ring that they thought were rude. Several other actions were cited less frequently, including browsing the Internet, excusing oneself from a meeting to take a call, bringing a phone to a meeting, and checking the time with a phone. In an open-ended format, we got some sense of the intensity of some of these comments.",[1],Computer_Science,train,1.0,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1007/s10055-018-0346-3,Computer_Science_easy_30,"In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.",This suggests that memory was only enhanced for those aspects of the environment that were interacted with directly-particularly the environment which was navigated.,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","However, they also found that there was no statistically significant difference between the recall or recognition of objects (such as furniture or entrances and exits of a room) or their positions within the environment between the active and passive participants. This suggests that memory was only enhanced for those aspects of the environment that were interacted with directly-particularly the environment which was navigated. The study found that when the building was a single floor, the real-world and virtual-environmenttrained users had comparable results.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1287/mnsc.2016.2500,Computer_Science_easy_31,"The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","Moreover, the alignment between operations and marketing strategies should exist to benefit organizational performance Van Der Velde 1991, Rhee and .","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","Thus, our study provides empirical evidence on the influence of checked baggage fee policies on airlines' operational performance. Moreover, the alignment between operations and marketing strategies should exist to benefit organizational performance Van Der Velde 1991, Rhee and . Yet co-ordination between them is critical for firm success.""",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.robot.2015.01.003,Computer_Science_easy_32,The ideas introduced by Poincare can be better explained with a simple example.,"Interestingly, from an external point of view, this manifold corresponds to the manifold of external agent's configurations in space.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","This structure can be processed as a manifold by defining a metric on the motor sets. Interestingly, from an external point of view, this manifold corresponds to the manifold of external agent's configurations in space. It is important to note, though, that to perform such an analysis, the agent does not need to assume the existence of space.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1088/1741-2560/13/2/026017,Computer_Science_easy_33,"The researchers note there was no pre-training required for the subject to gain this level of control, and the entire experiment took less than two hours.","The combined length across all 382 samples was approximately 43 min, with a total of only about 24 min when ignoring silence sample points.","""It makes sense that coupling these two fingers improved the accuracy."" The researchers note there was no pre-training required for the subject to gain this level of control, and the entire experiment took less than two hours. Crone cautions that application of this technology to those actually missing limbs is still some years off and will be costly, requiring extensive mapping and computer programming.","Most stimuli were presented to each subject multiple times, although the number of presentations of each stimulus varied by subject due to these external constraints. The combined length across all 382 samples was approximately 43 min, with a total of only about 24 min when ignoring silence sample points. 2.1.3.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1073/pnas.1419704112,Computer_Science_easy_34,"This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""","Despite the likely establishment of new Polynesian languages from relatively small colonizing populations, we do not find that a founder model describes our data better than one of gradual loss of words.","Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language."" It should also be clarified that the only occasions on which a Redditor might rage quite a cat cafe are when no bacon is available; or if it's one of those Redditors who show up in the ""unpopular opinions"" AskReddit threads hating on cats.","Although a small population of founders cannot carry all of the genetic alleles of a large parent population, it may be possible for a small number of speakers to use all of the basic vocabulary from the parent language (40). Despite the likely establishment of new Polynesian languages from relatively small colonizing populations, we do not find that a founder model describes our data better than one of gradual loss of words. If the finding that rates of word gain are greatest in large populations is a general feature of language change, then it has implications for understanding the connection between rate of language change and the diversification of language families.",[1],Computer_Science,train,1.0,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1098/rspb.2019.0646,Computer_Science_easy_35,"When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns.","Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment.","When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns. Turns out, it's all about psychology. In other words, the female guppy is often immune to the charms of a male guppy that looks like all the other male guppies.","Optimal countershading appears to be strongly illumination dependent [61] and having suboptimal countershading seems to be almost as bad as having no countershading at all, at least in a study with highly different illumination conditions . Future studies with a more gradual range of illuminations may help to determine if countershading has more general benefits, or if it is truly a strategy that is only effective in a specific light environment. While the study of imperfect camouflage is valuable in its own right, it also has a number of important implications for other areas of biology.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1007/s10055-018-0346-3,Computer_Science_easy_37,The researchers found that people remember information better if it is presented to them in a virtual environment.,5 The overall average recall performance of participants in the HMD condition was 8.8% higher compared to the desktop condition.,"The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","In addition, the difference in the incorrect answers was statistically significant, shown using a paired t test with Bonferroni-Holm correction resulting in p = 0.0195 < 0.05. 5 The overall average recall performance of participants in the HMD condition was 8.8% higher compared to the desktop condition. The median recall accuracy percentage for HMD was 90.48% and for desktop display was 78.57%.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_38,"The meat is light, a little salty and, of course, very greasy.","The color of meat cooked to the same temperature depends on how quickly it reaches that temperature and on how long it's held at that temperature: the faster it comes up to temperature, the redder it is; the longer it's held at a particular temperature, the paler it becomes ; see Figure 3 for meat cooked at 55","The skin, which offers a slight crunch when prepared perfectly, is the best part. The meat is light, a little salty and, of course, very greasy. McDonaldas, because theyare more delicious.","Note that while two similar cuts cooked to the same internal temperature will have a similar plumpness and juiciness, their color may be different. The color of meat cooked to the same temperature depends on how quickly it reaches that temperature and on how long it's held at that temperature: the faster it comes up to temperature, the redder it is; the longer it's held at a particular temperature, the paler it becomes ; see Figure 3 for meat cooked at 55 • C/131",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_39,"In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings.""","This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device.","""We also imagine that, for some patients, having implanted electrodes may not be the best option. In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings."" Such a cap, she says, also might also allow wireless transmission of information from patients, especially those living in remote locations, to neurologists who could tweak medications also being used in treatments.","This strategy requires further testing in a chronic ambulatory setting, and may be useful in PD patients who are motor fluctuators and experience severe dyskinesia alternating with marked bradykinesia . This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device. Lower panels show a zoomed in view to demonstrate that classifier state transitions correspond appropriately to fluctuations in gamma band power.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1016/j.compag.2016.07.028,Computer_Science_easy_40,But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant.,The weight of a certain pot on DAS 17 was 5398 g after watering.,"The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said. But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant. In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward.","ET ¼ ½ðW ði;afterÞ À FW i Þ À ðW ðiþ1;beforeÞ À FW iþ1 Þ=T ð1Þ The weight of a certain pot on DAS 17 was 5398 g after watering. The estimated shoot FW and DW were 17.53 and 1.53 g, respectively.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1287/mnsc.2016.2500,Computer_Science_easy_41,"""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance.","As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases.","""This offset any changes in carry-on luggage, and it helped airlines improve their on-time departure performance. The below-the-cabin effect dominates the above-the-cabin effect."" The findings, published in the journal Management Science, shows airlines improved their median departure time between 3.3 to 4.2 minutes and reduced average departure delays between 1.3 to 2 minutes, depending on whether they charged for the first or second checked bag.","Hence, given the previously hypothesized departure performances (i.e. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time decreases.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1073/pnas.1411728112,Computer_Science_easy_42,"Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions.","""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","While macroscopically, only a single second law restricts transitions, we find that there are an entire family of more fundamental restrictions at the quantum level. At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions. What's more, one needs to be more precise about what one means by a cyclic process.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/978-3-642-55220-5_1,Computer_Science_easy_43,The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier.,(The authors of proposed another solution to keep the quasi-polynomial nature of algorithm.),"This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms. The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier. Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option.","Similarly, if P is linear, its presence will prevent the second part of Proposition 2 to hold since the logarithm of P can not be found with the strategy of Section 4. (The authors of proposed another solution to keep the quasi-polynomial nature of algorithm.) Proposition 10 For each problematic polynomial P of degree D, we can find a linear relation between log P , log h 1 and O(D) logarithms of polynomials of degree at most (δ − 1)D which are not problematic.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_45,could be instilled in biological or artificial systems.,The agent must somehow know that its sensor is at the same spatial position independently of what objects are around and what are the positions of the other sensors.,"a) 1% of the 2500 exploratory arm configurations mi . could be instilled in biological or artificial systems. ""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to.","The first and most basic property of those laws is an invariance: space does not depend on the particular environment, nor on the particular posture of the agent. The agent must somehow know that its sensor is at the same spatial position independently of what objects are around and what are the positions of the other sensors. These ""points of view"" are the precursors to the more convenient notion of ""point"", which is the basic element of what we call space, and which can be used to build more complex notions of space.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.robot.2015.01.003,Computer_Science_easy_47,The ideas introduced by Poincare can be better explained with a simple example.,"The robot should start from scratch and gradually develop perceptual notions, under no prior assumptions, exclusively by looking into its sensorimotor experience and identifying repetitive patterns and invariants.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","In a sufficiently rich environment, the kernels of these functions correspond uniquely to the spatial configuration of the agent's exteroceptors. The robot should start from scratch and gradually develop perceptual notions, under no prior assumptions, exclusively by looking into its sensorimotor experience and identifying repetitive patterns and invariants. One of the most fundamental perceptual notions, space, cannot be an exception to this requirement.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_50,Itas hard to eat more than a few at a time because of the overwhelming seasoning.,Precise temperature control gives more choice over doneness and texture than traditional cooking methods.,"Fresh, free of antibiotics and all the other buzzwords give it the advantage here. Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part.","Precise temperature control gives more choice over doneness and texture than traditional cooking methods. Cooking in heat-stable, vacuumized pouches improves shelf-life and can enhance taste and nutrition. Vacuum-sealing has several benefits: it allows heat to be efficiently transferred from the water (or steam) to the food; it increases the food's shelf-life by eliminating the risk of recontamination during storage; it inhibits off-flavors from oxidation and prevents evaporative losses of flavor volatiles and moisture during cooking ; and reduces aerobic bacterial growth -this results in especially flavorful and nutritious food .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_51,"However, if we move 10 cm left, the image we see will remain almost exactly the same.","The sets M s thus take the form of oblique lines, such that m 1 + m 2 = x (see Fig.","The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same. ""This property seems miraculous if you think about how many receptors the human body has,"" Terekhov said.","For the example under consideration, the two motor commands m 1 and m 2 are redundant in determining the agent's position x in space . The sets M s thus take the form of oblique lines, such that m 1 + m 2 = x (see Fig. In general and for any agent, if the environment E is rich enough, the sensory input s is different for different positions of the exteroceptors in Figure 2 : The agent can move its sensors using two redundant motors.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1145/2872427.2883081,Computer_Science_easy_52,"When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant.","In response to the same original post, there are many possible ways to change someone's view.","Emotions like anxiety, fear, and anger exacerbate political bias, so use soft wording and a calm tone, and try to make them feel at ease. When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant. This implies that the persuader is already open-minded and aware of their own biases, which is important.","So, while the challenger's opening argument should be important, statements made later in the rooted path-unit could be more important. In response to the same original post, there are many possible ways to change someone's view. Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1287/mnsc.2016.2500,Computer_Science_easy_53,"The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis.","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","Since Southwest Airlines is the only major U.S. airline that does not charge for two checked bags, it resembles a control variable of operational performance in a quasi-experiment 3 when compared against competing airlines (that did begin charging for checked bags) that operated in the same airports. As Southwest Airlines might have gotten new customers who used to fly the now-baggage fee charging airlines, we do not have a true experiment, and consequently we do not employ a traditional difference-in-difference approach in our analysis. We show that, at the aggregate level, the airlines that began charging for one checked bag saw a significant relative improvement in their on-time departure performance in the 35-day period afterwards, compared to the airlines that were not charging for a checked bag during the same time period.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1177/1080569913501862,Computer_Science_easy_54,"Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.",Roughly 71% of the professionals said they would not make a call or take a call during a meeting.,"Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65. Chances are, just having your phone out is offending somebody: A full 20 percent of professionals said simply having your phone out at a business lunch is rude.","Interestingly, just 24% thought using a laptop in a meeting was not appropriate. Roughly 71% of the professionals said they would not make a call or take a call during a meeting. Approximately 63% said that they would not text message during meetings.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rspb.2019.0646,Computer_Science_easy_55,"When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns.","This would also allow manipulation of each feature dimension independently, giving the ability to ask questions about which aspects of the target are most important for effective compromise camouflage.","When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns. Turns out, it's all about psychology. In other words, the female guppy is often immune to the charms of a male guppy that looks like all the other male guppies.","It remains possible that there are different optimal strategies depending on the type of compromise adopted, and therefore future work should test whether there are differences between putative compromise camouflage strategies. This would also allow manipulation of each feature dimension independently, giving the ability to ask questions about which aspects of the target are most important for effective compromise camouflage. We can also use image analysis techniques to identify which forms of compromise camouflage we actually see in real animals.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1287/mnsc.2016.2500,Computer_Science_easy_57,"The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags.","Because our model includes a rich set of control variables, we are able to explain about 38% of the variation in Actual-TurnAroundTime variable.","The most positive changes in on-time departures occurred at major hub airports because less checked bags had to be moved through massive systems once passengers change planes. The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","To rule out the possibility that our results are driven by other factors within the air- This incremental effect is also consistent with the incremental effect caused by the two checked bags fees policy on SpAdj-Departure-Delay. Because our model includes a rich set of control variables, we are able to explain about 38% of the variation in Actual-TurnAroundTime variable. average delay in the After period minus average delay in the Before period.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1287/mnsc.2016.2500,Computer_Science_easy_58,The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year.,"), and lastly, security delay.","Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags. The study estimates Southwest loses approximately $24 million for not charging for the first checked bag and $35 million for not charging for the second one per year. ""It's not free in an operational sense,"" Arikan says.","The weather shows up as the main source of delays, followed by air carrier delay (e.g. ), and lastly, security delay. Hence, our conclusions related to baggage fees and departure delays are robust,",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_easy_59,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","In general, participants were more often correct in the HMD condition than for the desktop condition for a given confidence level.","""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.","9 show that when the users were less error-prone in the HMD condition, their confidence was better-grounded in the recall accuracy than when in the desktop condition. In general, participants were more often correct in the HMD condition than for the desktop condition for a given confidence level. Figure 10 shows the accuracy when using the desktop first followed by the HMD versus using the HMD first and then the desktop.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1287/mnsc.2016.2500,Computer_Science_easy_60,Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.,"use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway.","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","Thus, our findings also support the notion that Southwest's marketing strategy of being the only major U.S. airline not charging for the first two checked bags is in line with their historical operations oriented strategy. use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway. Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1088/1741-2552/aabc9b,Computer_Science_easy_62,"""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal.""",Stimulation parameters used for adaptive DBS are shown in,"The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods. ""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal."" An adaptive system like the one being tested here could offer an effective alternative and may also limit adverse effects of traditional deep brain stimulation, but considerable testing remains to be done.","The narrowband gamma signal related to dyskinesia occurs at half the stimulation frequency, when dyskinesia is present ( Figure 1A and 1C) . Stimulation parameters used for adaptive DBS are shown in This match was closer for the Nexus E session than for Nexus D3.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1007/978-3-642-55220-5_1,Computer_Science_easy_63,The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier.,On the one hand one can obtain a better complexity if one proves a stronger result on the smoothness probability.,"This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms. The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier. Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option.","The algorithm can be modified in several ways. On the one hand one can obtain a better complexity if one proves a stronger result on the smoothness probability. On the other hand, without changing the complexity, one can obtain a version which should behave better in practice.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1088/1741-2552/aabc9b,Computer_Science_easy_68,"Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation.","He never had tremor, so these scores were not included in the analysis.","This adaptation of the stimulation is the advance we are trying to make with brain stimulation."" Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation. Researchers saw energy savings of 39 percent and 45 percent in the devices when using the adaptive algorithms.","This match was closer for the Nexus E session than for Nexus D3. He never had tremor, so these scores were not included in the analysis. The blinded neurologist reviewed video during both sessions and reported no overt clinical difference between adaptive DBS (Nexus E) and open-loop DBS.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1098/rstb.2008.0288,Computer_Science_easy_69,And MRIs showed that the successful trainees' hippocampi had grown over time.,Evidence that this pattern of grey matter volume was acquired from the experience of learning and using the highly complex mental map of London comes from an additional finding.,"When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier. And MRIs showed that the successful trainees' hippocampi had grown over time. The successful trainees did not perform better on all tests of memory, however.","On the basis of these results, we suggested that learning, representing and using a spatial representation of a highly complex and large-scale environment is a primary function of the posterior hippocampus in humans such that this brain region might adapt structurally to accommodate its elaboration. Evidence that this pattern of grey matter volume was acquired from the experience of learning and using the highly complex mental map of London comes from an additional finding. The number of years of navigation experience correlated with hippocampal grey matter volume only in taxi drivers (and not bus drivers who were matched for number of years navigating in London), with right posterior grey matter volume increasing with more navigation experience (figure 3d ).",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1007/978-3-642-55220-5_1,Computer_Science_easy_70,"For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","This can be used to solve certain discrete logarithms in, say, F 2 n for adequately chosen n (much similar to records tackled by ).","This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research. For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","Much the same can be said in the case where n is composite and factors nicely, so that F Q admits a large enough subfield F q with q = p m . This can be used to solve certain discrete logarithms in, say, F 2 n for adequately chosen n (much similar to records tackled by ). While we have seen that Corollary 4 can be used to treat some cases, its applicability might be hindered by the absence of an appropriately sized subfield: p might be as small as 2, and n might not factor adequately.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1145/2872427.2883081,Computer_Science_easy_71,"It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now.","Similar patterns occur in root reply and full path: in number of common words and OP fraction, persuasive arguments have larger values because they tend to be longer, as will be shown in §4.2.2; in reply fraction and Jaccard, which are normalized by reply length, persuasive arguments are more dissimilar from the original post in content words but more similar in stopwords.","It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now. From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation. But completely giving up on the task of converting fellow Americans--even staunch Trump supporters and outlandish conspiracy theorists--into crusaders for logic and reason should not be an option.","The features based on interplay are all significant to a certain degree. Similar patterns occur in root reply and full path: in number of common words and OP fraction, persuasive arguments have larger values because they tend to be longer, as will be shown in §4.2.2; in reply fraction and Jaccard, which are normalized by reply length, persuasive arguments are more dissimilar from the original post in content words but more similar in stopwords. Keeping in mind that the pairs we compare are chosen to be similar to each other, our analysis indicates that, under this constraint, persuasive arguments use a more different wording from the original post in content, while at the same time matching them more on stopwords.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34828472692&p=1pl&v=1&x=4ruYvZS5w6QcN2Gi21xOEg
10.1007/s10055-018-0346-3,Computer_Science_easy_72,"""We believe the future of education and innovation will benefit greatly from the use of these new visual technologies.""","If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.","The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education. ""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says. ""We believe the future of education and innovation will benefit greatly from the use of these new visual technologies.""","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.robot.2015.01.003,Computer_Science_easy_73,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""",The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs.,"These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment. The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs. In a sufficiently rich environment, the kernels of these functions correspond uniquely to the spatial configuration of the agent's exteroceptors.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1007/s10055-018-0346-3,Computer_Science_easy_74,"""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.","The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us. Yet another interesting future direction of research could be to compare elements of virtual memory palaces that are highly personal versus those that could be used by larger groups.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1098/rstb.2008.0288,Computer_Science_easy_75,"The successful trainees did not perform better on all tests of memory, however.","This pattern of anterograde memory performance was in the context of learning and recognition memory for single items being comparable with control participants, as were retrograde memory for autobiographical and semantic information, executive and perceptual functions, working memory and levels of stress and anxiety.","And MRIs showed that the successful trainees' hippocampi had grown over time. The successful trainees did not perform better on all tests of memory, however. Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others.","After a delay they also recalled less of this associative information. This pattern of anterograde memory performance was in the context of learning and recognition memory for single items being comparable with control participants, as were retrograde memory for autobiographical and semantic information, executive and perceptual functions, working memory and levels of stress and anxiety. Negative effects of navigation expertise were not only found behaviourally but also structurally in the brain.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.compag.2016.07.028,Computer_Science_easy_77,"Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","Compared to leaves, these organs have subtle differences in spectral signatures, which would lower the prediction accuracy.","Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","A larger fraction of the plant leaves are occluded from the hyperspectral camera and the pixels extracted from the images are therefore less representative of the entire plants. Compared to leaves, these organs have subtle differences in spectral signatures, which would lower the prediction accuracy. Total NIR reflectance appears to be influenced by leaf thickness in addition to water content, introducing confound- ing variation ( .",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1177/1080569913501862,Computer_Science_easy_79,Higher-income professionals had less tolerance for smartphone use in business meetings.,"As such, they may be more sensitive to subordinates who distract attention away from them during meetings.","Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","We suspect that one explanation is that higher-income at UNIV TORONTO on May 10, 2016 bcq.sagepub.com Downloaded from professionals are often in higher-status positions. As such, they may be more sensitive to subordinates who distract attention away from them during meetings. We think this research provides a baseline and foundation for future research.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_80,"When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier.","We suggest that exploring talent and expertise in this manner could have implications for education, rehabilitation of patients with cognitive impairments, understanding individual differences and possibly conditions such as autism where exceptional abilities can be a feature.","Four years later 39 of the 79 trainees had earned their licenses; 20 trainees who failed their exams agreed to continue participating in the study. When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier. And MRIs showed that the successful trainees' hippocampi had grown over time.","We suggest that exploring talent and expertise in this manner could have implications for education, rehabilitation of patients with cognitive impairments, understanding individual differences and possibly conditions such as autism where exceptional abilities can be a feature. Perhaps this is not surprising, given that even defining talent is not straightforward. In order to understand whether exceptional ability is innately determined or can be acquired, we suggest that in the first instance it is necessary to eschew development as an influencing factor and establish whether exceptional ability can develop in healthy adults.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1287/mnsc.2016.2500,Computer_Science_easy_81,"This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines.","As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases.","Other key findings from the study:

Charging for the first or second checked bag improved on-time departure performance for all major airlines--including Southwest Airlines, which does not charge for the first two bags--because it creates savings due to a cultural shift among US passengers to travel with less baggage. This shift resulted in a lower demand for airport labor-intensive, back-end operations such as baggage handling and security checks, which are shared resources across airlines. So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not.","Hence, given the previously hypothesized departure performances (i.e. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time increases. As the checked baggage fee policy gets implemented from zero to one to two bags, the scheduled block time decreases.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_easy_83,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","9 show that when the users were less error-prone in the HMD condition, their confidence was better-grounded in the recall accuracy than when in the desktop condition.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","The results in Fig. 9 show that when the users were less error-prone in the HMD condition, their confidence was better-grounded in the recall accuracy than when in the desktop condition. In general, participants were more often correct in the HMD condition than for the desktop condition for a given confidence level.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1098/rspb.2019.0646,Computer_Science_easy_86,"First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure.","In an evolutionary simulation model where the prey population could evolve distastefulness as well as its coloration, aposematic coloration evolved more often in a situation where the habitat was visually variable, consisting of two different microhabitats, than when the habitat always remained similar .","Through these experiments, researchers showed that this choice met four criteria that indicate habituation. First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure. Second, the females' interest in males with novel patterns was not affected by exposure to the familiar pattern, showing something called stimulus specificity.","First, there is evidence that imperfect camouflage may be an important driver for the evolution of aposematic coloration. In an evolutionary simulation model where the prey population could evolve distastefulness as well as its coloration, aposematic coloration evolved more often in a situation where the habitat was visually variable, consisting of two different microhabitats, than when the habitat always remained similar . Future work could investigate whether phylogenetic evidence supports this hypothesis and explore in real-world set-ups the extent to which imperfect camouflage can combine with aposematism and other signalling strategies (similarly to recent work on distance-dependent camouflage and aposematism ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1098/rstb.2008.0288,Computer_Science_easy_87,"In other words, taxi drivers had plumper memory centers than their peers.","This pattern of anterograde memory performance was in the context of learning and recognition memory for single items being comparable with control participants, as were retrograde memory for autobiographical and semantic information, executive and perceptual functions, working memory and levels of stress and anxiety.","Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks. In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","After a delay they also recalled less of this associative information. This pattern of anterograde memory performance was in the context of learning and recognition memory for single items being comparable with control participants, as were retrograde memory for autobiographical and semantic information, executive and perceptual functions, working memory and levels of stress and anxiety. Negative effects of navigation expertise were not only found behaviourally but also structurally in the brain.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1177/1080569913501862,Computer_Science_easy_88,"Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women.","Strong majorities of younger employees (21 to 30 years old) considered checking text messages and emails, answering calls, and even writing text messages and emails as appropriate.","More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate. Similarly, 50 percent of men said it was acceptable to answer a call at a power lunch, compared to 26 percent of women. Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast.","The divide is perhaps most dramatic in informal meetings (see Figure 2 ). Strong majorities of younger employees (21 to 30 years old) considered checking text messages and emails, answering calls, and even writing text messages and emails as appropriate. On the other hand, strong majorities of employees above 41 years of age consider these actions as inappropriate.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1411728112,Computer_Science_easy_89,"That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","The same holds true for other versions of the second law, such as the Kelvin-Planck statement, where one also talks about cyclic processes, in which all other objects beside the system of interest are returned back to their original state.","For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly."" The results of the study give an improved understanding of how heat and energy is transformed on very small scales.","Interpreted strictly, the Clausius statement of the second law, applies to situations which never occur in nature. The same holds true for other versions of the second law, such as the Kelvin-Planck statement, where one also talks about cyclic processes, in which all other objects beside the system of interest are returned back to their original state. While macroscopically, only a single second law restricts transitions, we find that there are an entire family of more fundamental restrictions at the quantum level.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_91,This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.,"A similar approach, formalized in the language of information theory , can make it possible to describe the topological structure of the agent's surface and certain properties of its interaction with the environment .","Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent. ""He suggested that the coincidence in the sensory input may play a crucial role.""","This approach, when applied to visual information, can lead to the discovery of stable features, such as edges, similar to those present in the human visual cortex . A similar approach, formalized in the language of information theory , can make it possible to describe the topological structure of the agent's surface and certain properties of its interaction with the environment . However, only the simplest perceptual notions are straightforwardly dictated by the sensory inputs themselves.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1088/1741-2552/aabc9b,Computer_Science_easy_92,"In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings.""","The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded.","""We also imagine that, for some patients, having implanted electrodes may not be the best option. In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings."" Such a cap, she says, also might also allow wireless transmission of information from patients, especially those living in remote locations, to neurologists who could tweak medications also being used in treatments.","While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches. The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded. Although this approach has shown promise 1,2 , the STN LFP is a low amplitude signal that is strongly affected by stimulation artifact when stimulation is delivered on adjacent contacts.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1007/s10055-018-0346-3,Computer_Science_easy_93,"""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.",The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.",This makes it possible to compare recall for the same user across the two display modalities. The participants who experienced the virtual airport in a HMD had more accurate recall than those who used the desktop. They found that active participants had a superior environment layout recall compared to those who were passive.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/s10055-018-0346-3,Computer_Science_easy_94,"""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.",This suggests that memory was only enhanced for those aspects of the environment that were interacted with directly-particularly the environment which was navigated.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","However, they also found that there was no statistically significant difference between the recall or recognition of objects (such as furniture or entrances and exits of a room) or their positions within the environment between the active and passive participants. This suggests that memory was only enhanced for those aspects of the environment that were interacted with directly-particularly the environment which was navigated. The study found that when the building was a single floor, the real-world and virtual-environmenttrained users had comparable results.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1145/2872427.2883081,Computer_Science_easy_95,"ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away.","The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle.","Support these facts with data from scientific or politically-neutral sources. ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason.","But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length. The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle. These differences are indicative of the functions that the two forms of utterances serve: a CMV rule is that original posts should not be ""like a persuasive essay"".",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1007/978-3-642-55220-5_1,Computer_Science_easy_96,"For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.",On the one hand one can obtain a better complexity if one proves a stronger result on the smoothness probability.,"This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research. For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","The algorithm can be modified in several ways. On the one hand one can obtain a better complexity if one proves a stronger result on the smoothness probability. On the other hand, without changing the complexity, one can obtain a version which should behave better in practice.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_97,Itas hard to eat more than a few at a time because of the overwhelming seasoning.,Some chefs prefer the lower temperature of a skillet with just smoking vegetable or nut oil (200,"Fresh, free of antibiotics and all the other buzzwords give it the advantage here. Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part.","• C/3 500 • F in air, and produce a particularly nice crust on beef; Baldwin (2008) and recommend using a butane blowtorch since propane can leave an off-flavor. Some chefs prefer the lower temperature of a skillet with just smoking vegetable or nut oil (200 Since the searing time at these high temperatures is very short (5-30 seconds), mutagens formation is unlikely to be significant (Skog, 2009 ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1126/science.aaf2654,Computer_Science_easy_98,"Instead, cognitive responses of overall-well being seem to be at play there, rather than a concrete focus on harm, the authors note in their paper.","Regression analyses (see Supplementary online materials) showed that enthusiasm for self-driving cars was consistently greater for younger, male participants.","Their hypothesis was accurate, but as they also predicted, they didn't find an association between brain activity and harming a person for the benefit of the public. Instead, cognitive responses of overall-well being seem to be at play there, rather than a concrete focus on harm, the authors note in their paper. Overall, the findings of the small study suggest some good news: people may actually be concerned about harming others during moral dilemmas, rather then just take into account their own discomfort.","A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far. Regression analyses (see Supplementary online materials) showed that enthusiasm for self-driving cars was consistently greater for younger, male participants. Accordingly, all subsequent analyses included age and sex as covariates.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32987984951&p=1pl&v=1&x=1g42vs7c-hPYDcKYkzy-jQ
10.1287/mnsc.2016.2500,Computer_Science_easy_100,"Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service.","Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays.","So, a drop in total baggage volume benefits not only the airlines that charge baggage fees but also those that do not. Southwest's improved departure time performance was not as significant as its rival airlines, which did charge for checked bags, and it appears to have hurt one of Southwest's historical competitive advantages in customer service. Southwest's ""bags fly free"" policy is likely not free based on lost opportunity cost, mostly because it could be offering more flights per day with increased boarding times due to charging for checked bags.","use BTS data on 10 major airlines in the 1995-2001 period on Fridays on the 1,000 busiest routes, and find that multimarket contact has a positive effect on arrival delays, causing delays on the ground, more in the form of gate departure delays rather than time spent on the runway. Using over 800,000 individual flights scheduled between 50 major U.S. airports in January, April, and July of 2000 finds that the prevalence and duration of arrival delays are significantly greater on routes where only one airline provides direct service, and that weather, congestion, and scheduling decisions have a significant contribution to arrival delays. Using over 27,000 monthly route observations between 1997 to 2000, find that less competitive routes are characterized by lower service quality, in terms of both more frequent and longer flight delays.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1126/science.aaf2654,Computer_Science_easy_101,Most people preferred to not use a self-driving car.,"Thus, participants were not worried about AVs being too utilitarian, as often portrayed in science-fiction.","Overall, the findings of the small study suggest some good news: people may actually be concerned about harming others during moral dilemmas, rather then just take into account their own discomfort. Many of us will never be in the situation of choosing to silence a crying baby during wartime. Most people preferred to not use a self-driving car.","Participants were not quite so sure that AVs would be programmed that way though (67% thought so, with a median rating of 70). Thus, participants were not worried about AVs being too utilitarian, as often portrayed in science-fiction. If anything, they imagined future AVs as being less utilitarian than they should be.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32987984951&p=1pl&v=1&x=1g42vs7c-hPYDcKYkzy-jQ
10.1098/rstb.2008.0288,Computer_Science_easy_102,"""But it turns out it really was the training process that caused the growth in the brain.","Clearly, increased numbers of participants are required to confirm these findings.","""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain. It shows you can produce profound changes in the brain with training.","Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ). Clearly, increased numbers of participants are required to confirm these findings. Nevertheless, the possibility of plasticity effects in both directions, i.e.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_103,"The meat is light, a little salty and, of course, very greasy.","• C/180-185 • F. This cementing material can be strengthened by pre-cooking, say at 50","The skin, which offers a slight crunch when prepared perfectly, is the best part. The meat is light, a little salty and, of course, very greasy. McDonaldas, because theyare more delicious.","). • C/180-185 • F. This cementing material can be strengthened by pre-cooking, say at 50 • C/122",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_104,"Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","Monotonicity of F α (ρ, ρ β ) thus provides a powerful tool to determine what sorts of thermodynamical transitions are possible on the quantum scale, or equally well, for systems which have long range interactions.","In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered.","This includes ergodicity, mixing, coarse-graining of degrees of freedom and lack of control over the system. Monotonicity of F α (ρ, ρ β ) thus provides a powerful tool to determine what sorts of thermodynamical transitions are possible on the quantum scale, or equally well, for systems which have long range interactions. From a foundational perspective, the laws of thermodynamics take on a very simple and elegant forma class of operations, and a set of statistical distances to the free state ρ β which can never decrease.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/978-3-642-55220-5_1,Computer_Science_easy_105,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,"All of them can be done in polynomial time in q and the degree of P (X) which is bounded by k. Finally, the linear algebra step can be done in O(q 2ω ) using asymptotically fast matrix multiplication algorithms, or alternatively O(q 5 ) operations using sparse matrix techniques.","Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","Since the order of PGL 2 (F q i ) is q 3i − q i , the set of cosets P q has q 3 + q elements. All of them can be done in polynomial time in q and the degree of P (X) which is bounded by k. Finally, the linear algebra step can be done in O(q 2ω ) using asymptotically fast matrix multiplication algorithms, or alternatively O(q 5 ) operations using sparse matrix techniques. Indeed, we have q + 1 non-zero entries per row and a size of q 2 + 1.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2019.0646,Computer_Science_easy_106,"First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure.",These findings suggest that improving our understanding of the situations in which imperfect camouflage can offer protection may help conservationists decide how best to protect threatened species.,"Through these experiments, researchers showed that this choice met four criteria that indicate habituation. First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure. Second, the females' interest in males with novel patterns was not affected by exposure to the familiar pattern, showing something called stimulus specificity.","This translocation therefore potentially reduced genetic diversity, which may have important consequences for conservation, particularly in cases where populations are already small. These findings suggest that improving our understanding of the situations in which imperfect camouflage can offer protection may help conservationists decide how best to protect threatened species. Similarly to camouflage, these conspicuous colour signals can also be considered within a generalist or specialist adaptation framework.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1145/2872427.2883081,Computer_Science_easy_107,"This implies that the persuader is already open-minded and aware of their own biases, which is important.","However, it is consistent that successful arguments are less similar to the original post in content words.","When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant. This implies that the persuader is already open-minded and aware of their own biases, which is important. I think it is safe to say that most Americans, regardless of political affilitation, want what is best for America.","If we instead use truncation to (artificially) control for reply length, persuasive arguments present lower similarity in all metrics, suggesting that effects might differ over local parts of the texts. However, it is consistent that successful arguments are less similar to the original post in content words. These features attempt to capture linguistic style and its connections to persuasion success.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1007/s10055-018-0346-3,Computer_Science_easy_108,Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training.,"In addition, there was no statistical difference in performance for the simple task for the different levels of immersion.","Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","The study found that higher levels of immersion (in this case, field of view) were more effective in learning complex procedures that reference spatial locations. In addition, there was no statistical difference in performance for the simple task for the different levels of immersion. found that higher field of view and field of regard produced a statistically significant performance improvement.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1145/2872427.2883081,Computer_Science_easy_109,"From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation.","But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length.","It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now. From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation. But completely giving up on the task of converting fellow Americans--even staunch Trump supporters and outlandish conspiracy theorists--into crusaders for logic and reason should not be an option.","This is not surprising: longer replies can be more explicit and convey more information. But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length. The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34828472692&p=1pl&v=1&x=4ruYvZS5w6QcN2Gi21xOEg
10.1073/pnas.1411728112,Computer_Science_easy_111,"They showed that not only does entropy increase, but other types of disorder also have to increase.","For some properties of Rényi divergence, the reader can refer to [36, 37] .","The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder. They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails.","Also, there exists a useful relation between two divergences for α ∈ {0, 1}: For some properties of Rényi divergence, the reader can refer to [36, 37] . Note that discussions in other literatures define Rényi divergence for only non-negative alphas.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_112,"This implies that the persuader is already open-minded and aware of their own biases, which is important.","Persuasive arguments use consistently more links, both in absolute and in per-word count.","When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant. This implies that the persuader is already open-minded and aware of their own biases, which is important. I think it is safe to say that most Americans, regardless of political affilitation, want what is best for America.","In both root reply and full path, persuasive arguments use a significantly larger absolute number of personal pronouns. Persuasive arguments use consistently more links, both in absolute and in per-word count. Maybe due to high recall, .com links seem to be most powerful.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_113,The ideas introduced by Poincare can be better explained with a simple example.,"The method we developed allows the agent, starting with minimal a priori knowledge, to capture those constraints and to build an internal representation of its external configuration in space.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","In particular, the structure of the external space as such manifests itself through the constraint that certain properties of these functions should not depend on the objects present in the environment. The method we developed allows the agent, starting with minimal a priori knowledge, to capture those constraints and to build an internal representation of its external configuration in space. It requires the agent to notice that different motor commands can result in identical sensory inputs.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1098/rspb.2019.0646,Computer_Science_easy_114,"Turns out, it's all about psychology.",We are also starting to be able to quantify complexity across the UV visible spectrum and therefore more accurately represent non-human visual systems .,"***EMBARGOED UNTIL 7:01 P.M. May 14 EDT ***

FOR IMMEDIATE RELEASE

CONTACT: Kathleen Haughney, University Communications

(850) 644-1489; khaughney@fsu.edu

@FSUResearch

May 2019

IN GUPPY COURTSHIP, THE UNUSUAL MALE WINS

New FSU Study Shows Psychological Concept Underpins Mating Choices

Newswise -- TALLAHASSEE, Fla. -- When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns. Turns out, it's all about psychology. In other words, the female guppy is often immune to the charms of a male guppy that looks like all the other male guppies.","The most appropriate forms of imperfect camouflage may vary in more realistic situations, such as when the complexity of the habitats varies. We are also starting to be able to quantify complexity across the UV visible spectrum and therefore more accurately represent non-human visual systems . These developments open up exciting new avenues for compromise camouflage research, which to date has only used similar backgrounds , therefore probably testing only one level of complexity.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39225183970&p=1pl&v=1&x=kt9epreGa8FUuUQ7RXzVww
10.1016/j.robot.2015.01.003,Computer_Science_easy_115,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.",Note that in very peculiar environments this statement can be false.,"If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","Any external configuration x of the sensors is thus internally related to a set of redundant motor configurations M i . Note that in very peculiar environments this statement can be false. Seen through the agent's sensors, some environments could for instance present symmetries such that multiple spatial configurations of the agent would generate the same sensory input.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.compag.2016.07.028,Computer_Science_easy_116,But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant.,The temporal dynamics of growth patterns can be clearly identified.,"The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said. But teasing apart a plant's water weight from its new biomass growth - and subsequently determining how efficiently each plant turned water into new tissue - required multiple steps that ultimately destroyed the plant. In killing the plant, these methods kept the researchers from observing how it would have grown and developed afterward.","4 shows the accumulation of shoot FW of 60 maize plants by genotype and water treatment at the first stage of the experiment (DAS 6 to 26). The temporal dynamics of growth patterns can be clearly identified. From DAS 6 to DAS 10 when the drought stress had not started, the difference was mainly between genotypes, with B73 showing greater shoot FW than FFMM-A.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1098/rstb.2008.0288,Computer_Science_easy_117,"When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier.","Knowing the answers to these questions could be beneficial to those of us wishing to become skilled, for educationalists too, and for those involved in rehabilitation of patients with cognitive impairments.","Four years later 39 of the 79 trainees had earned their licenses; 20 trainees who failed their exams agreed to continue participating in the study. When Maguire gave the successful and disappointed trainees the same battery of memory tests she had given them at the start of their training, she found that drivers who earned their licenses performed far better than those who failed--even though they had performed equally four years earlier. And MRIs showed that the successful trainees' hippocampi had grown over time.","The skill we selected for investigation is widely acknowledged to be impressive and, moreover, with each participant being tested in a similar fashion by an independent body, the acquisition of expertise was verifiable. Knowing the answers to these questions could be beneficial to those of us wishing to become skilled, for educationalists too, and for those involved in rehabilitation of patients with cognitive impairments. Furthermore, the data relating to expertise in average healthy individuals may aid in the interpretation of skills in clinical populations such as autism, where exceptional abilities are known to feature ).",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1088/1741-2552/aabc9b,Computer_Science_easy_119,"This adaptation of the stimulation is the advance we are trying to make with brain stimulation.""",Furthermore the lessons learned from this approach may have broader implications.,"""Today's devices are much like cardiac pacemakers were a long time ago. This adaptation of the stimulation is the advance we are trying to make with brain stimulation."" Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation.","Reduction in stimulation current without loss of therapeutic benefit has the potential to reduce stimulation-induced adverse effects , as well as prolong battery life or allow greater miniaturization of the relatively large pulse generators now in use . Furthermore the lessons learned from this approach may have broader implications. While for some patients simply manually adjusting their own DBS settings might be sufficient to avoid frequent dyskinesia, for others, especially patients with very frequent motor fluctuations, such an approach would be cumbersome and imprecise.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1007/s10055-018-0346-3,Computer_Science_easy_120,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number.",The modality of interactive exploration of the virtual environment in the two conditions was different (head tracking versus mouse tracking).,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality. The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","persuasively argues for designing virtual environment studies that strike a balance between naturalistic observation and the need for exacting control over variables. The modality of interactive exploration of the virtual environment in the two conditions was different (head tracking versus mouse tracking). Thus, differences in the recall performance may be explained by this diverse interaction modality.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1007/s10055-018-0346-3,Computer_Science_easy_121,The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.,"This means participants were able to recall better in the HMD condition as compared to the desktop condition, permitting us to reject the null hypothesis.","""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education. ""By showing that virtual reality can help improve recall, it opens the door to further studies that look at the impact of VR-based training modules at all levels -- from elementary school children learning astronomy to trauma residents acquiring the latest knowledge in lifesaving procedures,"" Varshney says.","We found that there was a statistically significant effect for the display condition (HMD vs desktop) with F(1, 79) = 4.6 and p < 0.05 . This means participants were able to recall better in the HMD condition as compared to the desktop condition, permitting us to reject the null hypothesis. The overall average recall performance of participants in the HMD condition was 8.8% higher compared to the desktop condition with the mean recall accuracy percentage for HMD condition at 84.05% and the desktop condition at 75.24%.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1088/1741-2552/aabc9b,Computer_Science_easy_122,"""Today's devices are much like cardiac pacemakers were a long time ago.",We have demonstrated the technical feasibility of this approach within a totally implanted device.,"It works well, but with limitations,"" Swann says. ""Today's devices are much like cardiac pacemakers were a long time ago. This adaptation of the stimulation is the advance we are trying to make with brain stimulation.""","This last point bears particular consideration since often the contacts in STN which best detect signatures related to symptoms are also the contacts which correspond to the regions of STN most likely to be targeted for clinical use 1 . We have demonstrated the technical feasibility of this approach within a totally implanted device. While this cortical detection strategy does require insertion of a subdural lead for motor cortex recording, insertion of this ""extra"" lead is technically simple and can be done at the same time as insertion of the DBS leads, using the same skull opening and surgical exposure as used for the DBS leads .",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1145/2872427.2883081,Computer_Science_easy_123,"ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away.","shows an example where indeed, the OP described their point in reasonable detail, and the responders raised sensible objections.","Support these facts with data from scientific or politically-neutral sources. ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason.","It is a separate and interesting research question to understand what effects these rules have and why they were put in place. shows an example where indeed, the OP described their point in reasonable detail, and the responders raised sensible objections. The high amount of activity on CMV means that we can extract a large amount of data.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_124,The ideas introduced by Poincare can be better explained with a simple example.,This will be the main focus of the present paper.,"Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","Although these studies are in line with our approach, they do not directly address the problem of space perception (or only implicitly through the robot's ability to move in its environment). This will be the main focus of the present paper. Perceptual structures can emerge as stable patterns in the agent's sensorimotor flow.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1007/s10055-018-0346-3,Computer_Science_easy_126,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","We believe that if there were to be any implicit advantage, it would lie with the desktop, given the overall familiarity with it.","The questionnaire also found that only two people said they felt ""uncomfortable"" using VR. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display.","9 The number of errors made for each display condition for various confidence levels were for the second trials, the HMD-2 and desktop-2, with p = 0.025 < 0.05. We believe that if there were to be any implicit advantage, it would lie with the desktop, given the overall familiarity with it. Although we gave the participants enough time to get comfortable in the HMD before we began the study, we observed that many were not fully accustomed to the HMD, even though they performed better in it.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1073/pnas.98.2.676,Computer_Science_easy_127,"As Nixon notes, there needs to be much more research into the links between attention and productivity.",Deviations from this equilibrium produced by transient changes in this modal level of neural activity manifest themselves as changes in the OEF and provide us with the signals underlying modern functional brain imaging with fMRI.,"Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work. As Nixon notes, there needs to be much more research into the links between attention and productivity. The sharp decline in productivity after the financial crisis is what makes Nixon's line of enquiry interesting.",The uniformity of the OEF in the absence of specific goal-directed activities supports our belief that an established equilibrium exists between the local metabolic requirements necessary to sustain a long-term modal level of neural activity and the level of blood flow in a particular region. Deviations from this equilibrium produced by transient changes in this modal level of neural activity manifest themselves as changes in the OEF and provide us with the signals underlying modern functional brain imaging with fMRI. Note that these are all increases in the OEF signifying areas of deactivation in the baseline state of resting but awake with eyes closed.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1073/pnas.1411728112,Computer_Science_easy_128,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.","The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","In particular, we find a family of free energies which generalise the traditional one, and show that they can never increase. The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions. We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is.",[1],Computer_Science,train,1.0,news,http://www.spacedaily.com/reports/On_quantum_scales_there_are_many_second_laws_of_thermodynamics_999.html
10.1186/s12911-017-0526-1,Computer_Science_easy_131,"""Most stakeholders felt very strongly that the information should be available wherever the patient wants it,"" Showalter said.",This suggests a need for decision aids to support communication of genomic expression profiling test results and informed decision-making.,"One major theme was that the tool should be useful both in the doctor's office, so patients can discuss care options with their physicians, and at home, so that they can compare various scenarios with their loved ones. ""Most stakeholders felt very strongly that the information should be available wherever the patient wants it,"" Showalter said. ""There should be a private web portal, there should be the ability to print and it should be available both at home, before the physician appointment, and in the doctor's office as well.","The guidance provided by our stakeholders may be broadly applicable to the communication of genomic test results to patients in a patient-centered fashion that supports effective shared decision-making that represents a spectrum of personal factors such as age, medical comorbidities, and individual priorities and values. This suggests a need for decision aids to support communication of genomic expression profiling test results and informed decision-making. Optimal implementation of genomic risk stratification tools, which have the potential to better match patients with the right treatments for them, should be performed within a patient-centered context that meets the National Academy of Medicine (formerly Institute of Medicine) goals for patient-centeredness by considering ""individual patient preferences, needs, and values, and ensuring that patient values guide all clinical decisions"" .",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1007/s10055-018-0346-3,Computer_Science_easy_132,"The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team.","Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information.","""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD. The results showed an 8.8 percent improvement overall in recall accuracy using the VR headsets, a statistically significant number according to the research team. In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform.","Other directions of future studies could include elements in the architecture of the virtual memory palaces such as their design, the visual saliency of the structure of model , their type, and various kinds of layouts and distribution of content that could help with recall. Another interesting future work would be to allow people to build their own virtual memory palaces, manipulate and organize the content on their own, and then ask them to recall that information. If their active participation in the organization of the data in virtual memory palaces makes a meaningful difference, then that could be further useful in designing interaction-based virtual environments that could one day assist in far superior information management and recall tools than those currently available to us.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1088/1741-2560/13/2/026017,Computer_Science_easy_133,"""It makes sense that coupling these two fingers improved the accuracy.""","Neural features performed better than chance in most situations (Wilcoxon for averaged results, Welch's for singletrial results, < p 0.01).","Once the researchers coupled the ring and pinkie fingers together, the accuracy increased to 88 percent. ""It makes sense that coupling these two fingers improved the accuracy."" The researchers note there was no pre-training required for the subject to gain this level of control, and the entire experiment took less than two hours.","The results for all of the subjects with standard deviations are given in table 5. Neural features performed better than chance in most situations (Wilcoxon for averaged results, Welch's for singletrial results, < p 0.01). The exceptions comprised of all estimation PER results, a subset of the single-trial confusion accuracy results, and the single-trial estimation posteriogram accuracy result with HGSs for subject B.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1088/1741-2552/aabc9b,Computer_Science_easy_135,"Such a cap, she says, also might also allow wireless transmission of information from patients, especially those living in remote locations, to neurologists who could tweak medications also being used in treatments.","Since this signature of dyskinesia is not disrupted by voluntary movement and occurs in a predictable frequency range, it is a promising control signal for adaptive DBS.","""We also imagine that, for some patients, having implanted electrodes may not be the best option. In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings."" Such a cap, she says, also might also allow wireless transmission of information from patients, especially those living in remote locations, to neurologists who could tweak medications also being used in treatments.","Moreover, during DBS at typical frequencies (i.e.130-10 Hz), if dyskinesia is present, the narrowband gamma oscillation occurs reliably at half the stimulation frequency , possibly because of neuronal entrainment (Figure 1A and 1C) . Since this signature of dyskinesia is not disrupted by voluntary movement and occurs in a predictable frequency range, it is a promising control signal for adaptive DBS. The study was registered at ClinicalTrials.gov (NCT0193296).",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1145/2872427.2883081,Computer_Science_easy_136,"It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now.","Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts.","It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now. From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation. But completely giving up on the task of converting fellow Americans--even staunch Trump supporters and outlandish conspiracy theorists--into crusaders for logic and reason should not be an option.","There are many possible extensions to our approach for representing arguments. Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts. Finally, beyond mechanisms behind persuasion, it is a vital research problem to understand how community norms encourage such a well-behaved platform so that useful rules, moderation practices, or even automated tools can be deployed in future community building.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34828472692&p=1pl&v=1&x=4ruYvZS5w6QcN2Gi21xOEg
10.1073/pnas.1411728112,Computer_Science_easy_137,"They showed that not only does entropy increase, but other types of disorder also have to increase.","However, the above ""change"" of Hamiltonian is not really a change: the Hamiltonian of the universe is fixed, and we simply have turned to another system with the required new Hamiltonian, and removed the system with the old Hamiltonian.","The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder. They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails.","In particular, in this way, one can go for free from the thermal state with one Hamiltonian to a thermal state with another Hamiltonian, which may seem to contradict a common thermodynamical paradigm, where changing the Hamiltonian is related to performing work. However, the above ""change"" of Hamiltonian is not really a change: the Hamiltonian of the universe is fixed, and we simply have turned to another system with the required new Hamiltonian, and removed the system with the old Hamiltonian. Thus in this case, while going from the thermal state (ρ β , H) to another thermal state (ρ β , H ) one does not gain any work, nor does one need any work while performing such an operation.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1126/science.aaf2654,Computer_Science_easy_138,"At the same time, the survey's respondents said, they would be much less likely to use a vehicle programmed that way.","The algorithm that swerved into one to save 10 always received many points, and the algorithm that swerved into one to save one always received few points.","At the same time, the survey's respondents said, they would be much less likely to use a vehicle programmed that way. ""But everybody want their own car to protect them at all costs."" ""If everybody does that, then we would end up in a tragedy ... whereby the cars will not minimize casualties,"" Rahwan adds.","Fig 3b shows the points allocated to the AV equipped with this algorithm, in three situations: when it swerved into a pedestrian to save 10 people, when it killed its own passenger to save 10 people, and when it swerved into a pedestrian to save just one other pedestrian. The algorithm that swerved into one to save 10 always received many points, and the algorithm that swerved into one to save one always received few points. Just as the high-valued algorithm, it received high marks for morality (median budget share = 50), and was considered a good algorithm for other people to have (median budget share = 50).",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/moral-dilemma-with-driverless-cars-who-gets-protected-the-driver-or-pedestrians/
10.1098/rstb.2008.0288,Computer_Science_easy_140,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition. Finally, it will also be vital to consider whether expertise and its related effects can be expected to develop in any individual or whether they are genetically determined.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_141,"Still, though, I had some lingering questions about their safety.",Food safety principles important for sous vide cooking are detailed in Section 4.,"They didn't melt, burn or make me sick. Still, though, I had some lingering questions about their safety. Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results.","Precise temperature control has more benefits for chefs than vacuumized packaging does: it allows almost-perfect reproducibility Achatz, 2008) ; it allows greater control over doneness than traditional cooking methods ; food can be pasteurized and made safe at lower temperatures, so that it doesn't have to be cooked well-done to be safe ; and tough cuts of meat (which were traditionally braised to make them tender) can be made tender and still be a medium or a medium-rare doneness ). Food safety principles important for sous vide cooking are detailed in Section 4. Some conclusions are drawn in Section 5.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1088/1741-2552/aabc9b,Computer_Science_easy_142,"The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","He never had tremor, so these scores were not included in the analysis.","Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods. ""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal.""","This match was closer for the Nexus E session than for Nexus D3. He never had tremor, so these scores were not included in the analysis. The blinded neurologist reviewed video during both sessions and reported no overt clinical difference between adaptive DBS (Nexus E) and open-loop DBS.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1016/j.robot.2015.01.003,Computer_Science_easy_143,The ideas introduced by Poincare can be better explained with a simple example.,"However, our approach differs from a large part of this literature by not assuming the pre-coding of building blocks or any processing of the sensory flow.","Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same.","Indeed, the notion of space is intimately related to the agent's ability to move [41] . However, our approach differs from a large part of this literature by not assuming the pre-coding of building blocks or any processing of the sensory flow. Our work adds to existing research by making explicit what properties of the raw sensorimotor flow can lead an agent to perceive space.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1007/978-3-642-55220-5_1,Computer_Science_easy_144,It discredits several cryptographic systems that until now were assumed to provide sufficient security safeguards.,We expect this event to be very unlikely.,"It discredits several cryptographic systems that until now were assumed to provide sufficient security safeguards. Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips, etc. The algorithm they devised stands out from the best algorithms known to date for this problem.","More generally, taking into account all the problematic polynomials, if when we apply Proposition 10 to them we get polynomials Q i of higher degrees, it could be that descending those we creates loops so that the logarithms of some of the problematic polynomials could not be computed. We expect this event to be very unlikely. Since in all our experiments it was always possible to obtain δ = 2, we did not investigate further.",[1],Computer_Science,train,1.0,news,http://www.homelandsecuritynewswire.com/dr20140518-new-algorithm-revolutionizes-cryptography
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_145,"But the seasoning kills any appeal, as does the lack of sauce options for those who need it.","The type of fat used to sear the meat in a pan has only minor effects on the formation of mutagens, but the pan residue using butter was significantly higher in mutagens than when using vegetable oil .","Fresh, antibiotic-free chicken breast you can order from an iPad a whatas not to love? But the seasoning kills any appeal, as does the lack of sauce options for those who need it. McNuggets, on the other hand, are perfect in both taste and consistency.","While adding glucose increases browning, it can decrease the production of mutagens . The type of fat used to sear the meat in a pan has only minor effects on the formation of mutagens, but the pan residue using butter was significantly higher in mutagens than when using vegetable oil . • C/3 500 • F in air, and produce a particularly nice crust on beef; Baldwin (2008) and recommend using a butane blowtorch since propane can leave an off-flavor.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1126/science.aaf2654,Computer_Science_easy_146,The MIT team was the first to figure out a way to balance all of these factors and produce a solution.,Study 4 (n = 267) offers another demonstration of this phenomenon.,Nearly all of them were white. Clearly something was off. The MIT team was the first to figure out a way to balance all of these factors and produce a solution.,"In other words, even though participants still agreed that utilitarian AVs were the most moral, they preferred the selfprotective model for themselves. Study 4 (n = 267) offers another demonstration of this phenomenon. For one of the algorithms, the AV would always swerve when it was about to run over people on the road.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37598037254&p=1pl&v=1&x=8McLEcTaeJE34juXGV2oZg
10.1145/2872427.2883081,Computer_Science_easy_147,"While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","Although it is a good-faith step for a person to post on CMV, some beliefs in the dataset are still ""resistant"" to changes, possibly depending on how strongly the OP holds them and how the OP acquired and maintained them .","While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them. ADVERTISEMENT

When you engage Trump loyalists in debate, try to respond with meaty content that has greater numbers of sentences and paragraphs, since research shows that one-liners and superficial statements do little to persuade people.","In root truncated, although the performance of style features drops significantly, interplay achieves very similar performance as in root reply, demonstrating the robustness of the interplay features. Although it is a good-faith step for a person to post on CMV, some beliefs in the dataset are still ""resistant"" to changes, possibly depending on how strongly the OP holds them and how the OP acquired and maintained them . Since CMV members must state their opinion and reasons for it in their own words, we can investigate differences between how resistant and malleable views are expressed.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1287/mnsc.2016.2500,Computer_Science_easy_148,Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.,"Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described.","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","As seen in Table 7 , the other control variables are also statistically significant. Thus, when examining departure delays over a longer period of time covering the time periods around the implementation dates of one checked bag and two checked bags fees policies, the fee for one checked bag showed the same impact as previously described. Moreover, the implementation of two checked bags fees policy indicated worse departure performance relative to the implementation of only one checked bag fee, as well as relative to not charging for checked bags.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1007/s10055-018-0346-3,Computer_Science_easy_149,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","Although we gave the participants enough time to get comfortable in the HMD before we began the study, we observed that many were not fully accustomed to the HMD, even though they performed better in it.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","We believe that if there were to be any implicit advantage, it would lie with the desktop, given the overall familiarity with it. Although we gave the participants enough time to get comfortable in the HMD before we began the study, we observed that many were not fully accustomed to the HMD, even though they performed better in it. All but two of the 40 participants stated they preferred the HMD for this task.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.neuroimage.2014.02.004,Computer_Science_easy_150,By employing movies it was possible to investigate the function of the human brain in experimental conditions that are close to natural.,"Most prominently, the time courses reflected activity in the early visual, posterior and inferior parietal, lateral temporo-occipital, and motor cortices, and in the STS region.","By employing movies it was possible to investigate the function of the human brain in experimental conditions that are close to natural. Viewing a movie creates multilevel changes in the brain function. Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds.","It is also useful to note that the same brain areas may contribute to several uncorrelated time-courses, likely reflecting the involvement of these regions in different functional processes. Most prominently, the time courses reflected activity in the early visual, posterior and inferior parietal, lateral temporo-occipital, and motor cortices, and in the STS region. The findings are concordant with previous fMRI studies but extend their findings by temporal information.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1145/2872427.2883081,Computer_Science_easy_153,"Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","But take heart, change does occur, as we shall show.","ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason. Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","One might think that the outcome is trivially ""no one ever changes their mind"", since people can be amazingly resistant to evidence contravening their beliefs 6] . But take heart, change does occur, as we shall show. Colors indicate distinct users.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_154,"In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings.""","Further, beta band phenomena are strongly affected by normal voluntary movement , which may complicate their use as signatures of motor impairment.","""We also imagine that, for some patients, having implanted electrodes may not be the best option. In the future, we might be able to use a EEG electrode placed in a fashionable cap to record data that could be used to inform changes in the settings."" Such a cap, she says, also might also allow wireless transmission of information from patients, especially those living in remote locations, to neurologists who could tweak medications also being used in treatments.","This ""adaptive DBS"" approach is promising but may be challenging to implement in fully implantable systems due to the small amplitude of the STN LFP coupled with the large stimulation artifact generated when sensing a signal in close proximity to the stimulating contact. Further, beta band phenomena are strongly affected by normal voluntary movement , which may complicate their use as signatures of motor impairment. Neural signatures may be detected in the motor cortex as well as the basal ganglia.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1145/2872427.2883081,Computer_Science_easy_155,"ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away.",Hedging is more common in persuasive arguments under root reply and full path.,"Support these facts with data from scientific or politically-neutral sources. ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason.","Their presence might signal a weaker argument , but alternately, they may make an argument easier to accept by softening its tone . Hedging is more common in persuasive arguments under root reply and full path. The absolute number of such example markers is significantly higher in persuasive arguments.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1007/s10055-018-0346-3,Computer_Science_easy_156,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.",Those in the HMD condition are slightly more confident about their answers than those in the desktop condition Fig.,"The questionnaire also found that only two people said they felt ""uncomfortable"" using VR. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display.","When comparing each participant's first trials, the desktop-1 and HMD-1, their distribution of recall scores was not significantly different with p = 0.62 > 0.05 , but they Fig. Those in the HMD condition are slightly more confident about their answers than those in the desktop condition Fig. 9 The number of errors made for each display condition for various confidence levels were for the second trials, the HMD-2 and desktop-2, with p = 0.025 < 0.05.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.neuroimage.2014.02.004,Computer_Science_easy_157,"Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds.","Intersubject correlations occurred in the STS region bilaterally and they were most prominently related to the first three canonical variates in the lowest, 0.03-1-Hz band.","Viewing a movie creates multilevel changes in the brain function. Despite the complexity of the stimulus, the elicited brain activity patterns show remarkable similarities across different people -- even at the time scale of fractions of seconds. ""The analysis revealed important similarities between brain signals of different people during movie viewing.",", likely related to activation of the dorsal attention network . Intersubject correlations occurred in the STS region bilaterally and they were most prominently related to the first three canonical variates in the lowest, 0.03-1-Hz band. STS involvement was to be expected because of the multitude of social stimuli and biological motion in the movie (for a review, see .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1080569913501862,Computer_Science_easy_158,"When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age.","There were significant differences by age, group, gender, region, and income level.","Which group you fall in is all about age and gender. When compared to women, men are almost twice as likely to find things like texting or answering calls appropriate in an informal meeting:

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There's also a massive difference based on age. Young people, 94% of whom own a mobile phone, find the whole spectrum of phone behavior more acceptable than older people, by a significant margin:



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Those differences are still there, if less pronounced, for more formal meetings:

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Certain parts of phone etiquette remain constant, but for younger people in particular, it's worth taking into account the people you're working with before making a grab for an iPhone.","There were significant differences by age, group, gender, region, and income level. The differences between women and men were quite striking, with men nearly twice as likely to consider various mobile phone behaviors as acceptable in informal meetings. Among Gen Y (18 to 29 years old) and Gen X (30 to 49 years old) adults, mobile phone ownership is 94% and 90%, respectively ).",[1],Computer_Science,train,1.0,news,http://www.businessinsider.com/gender-differences-in-phone-etiquette-2013-10
10.1098/rstb.2008.0288,Computer_Science_easy_159,"But we found them within the five years it took to do the study.""","From this, we conclude that the development of expertise is possible with extensive effort, and that this can be associated with neuropsychological and structural brain consequences.","""Maybe they only appeared quite some time after the trainees qualified. But we found them within the five years it took to do the study."" He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain.","Third, understanding exceptional abilities in the healthy brain may also offer benchmarks for interpreting talent and expertise in clinical populations, such as those with autism. From this, we conclude that the development of expertise is possible with extensive effort, and that this can be associated with neuropsychological and structural brain consequences. These effects can be positive and negative, with increased expertise and grey matter volume in some brain regions occurring in tandem with decreased performance on other tasks and decreased grey matter volume in neighbouring brain areas.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1088/1741-2552/aabc9b,Computer_Science_easy_160,"Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.","Use of Nexus D3 is associated with a more significant energy cost associated with streaming the data, which we did not consider for this study since the purpose of Nexus D3 was for prototyping our algorithms, not clinical application.","Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","Nevertheless, the energy saved surpassed the energy used. Use of Nexus D3 is associated with a more significant energy cost associated with streaming the data, which we did not consider for this study since the purpose of Nexus D3 was for prototyping our algorithms, not clinical application. During the adaptive DBS session using the external adaptive DBS system (Nexus D3), 72 transitions (instances where the threshold was crossed) were triggered (over 64 minutes) for Patient 1 (Figure 3 ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1126/science.aaf2654,Computer_Science_easy_161,"In what feels like a particularly dark period for democracy and during a time of increasingly out-of-control deployment of technology into society, I feel a lesson like this one has given me greater understanding of how we might more appropriately introduce algorithms into society.","If anything, they imagined future AVs as being less utilitarian than they should be.","A month later, a more nuanced picture emerged, one that I think offers insights into how technology can and should provide a platform for interacting with policy--and how policy can reflect a diverse set of inputs generated by the people it affects. In what feels like a particularly dark period for democracy and during a time of increasingly out-of-control deployment of technology into society, I feel a lesson like this one has given me greater understanding of how we might more appropriately introduce algorithms into society. Perhaps it even gives us a picture of what a Democracy 2.0 might look like.","Thus, participants were not worried about AVs being too utilitarian, as often portrayed in science-fiction. If anything, they imagined future AVs as being less utilitarian than they should be. Participants did not think that AVs should sacrifice their passenger when only one pedestrian could be saved (with an average approval rate of 23%), but their moral approval increased with the number of lives that could be saved (p < 0.001) up to approval rates consistent with the 76% observed in Study 1 (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37598037254&p=1pl&v=1&x=8McLEcTaeJE34juXGV2oZg
10.1007/s10055-018-0346-3,Computer_Science_easy_162,"""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.",The technique of memory palaces provides a natural spatial mnemonic to assist in recall.,"The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.",We believe this is a first step in using virtual environments for creating more memorable experiences that enhance productivity through better recall of large amounts of information organized using the idea of virtual memory palaces. The technique of memory palaces provides a natural spatial mnemonic to assist in recall. Such findings of contextdependent memory have interesting implications for virtual environments that have not yet been fully explored.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1098/rstb.2008.0288,Computer_Science_easy_163,But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.,"Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ).","It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place. Four years later 39 of the 79 trainees had earned their licenses; 20 trainees who failed their exams agreed to continue participating in the study.","In comparison with the posterior hippocampus that had greater grey matter volume compared with control participants, the anterior hippocampus had reduced grey matter volume in taxi drivers (Maguire et al. Moreover, anterior hippocampal grey matter volume decreased as navigation experience increased in taxi drivers (figure 5d ). We suggest that the belowaverage scores observed in taxi drivers on tests of anterograde associative memory could be related to their reduced right anterior hippocampal grey matter volume.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.compag.2016.07.028,Computer_Science_easy_164,"Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","It is quite likely that this technique can be extended to quantify plant chemical phenotypes including nitrogen content, photopigment concentration, and mineral content.","Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","Data points were missing on DAS 22 due to an unexpected disruption of the automated imaging routine on that day. It is quite likely that this technique can be extended to quantify plant chemical phenotypes including nitrogen content, photopigment concentration, and mineral content. The major conclusions drawn from this study are:",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/s10055-018-0346-3,Computer_Science_easy_165,Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training.,The reasons for these study design decisions are rooted in foundational research in psychology on memory.,"Photo by John T. C This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training. The researchers found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" says Amitabh Varshney, professor of computer science and dean of the College of Computer, Mathematical, and Natural Sciences at UMD.","In general, participants did not spend more than 5 min on this familiarization. The reasons for these study design decisions are rooted in foundational research in psychology on memory. From the seminal work by , we learn that the working memory can only retain 7 ± 2 items.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34297170515&p=1pl&v=1&x=aVyQCHIh9o0JvS5uzKIpiQ
10.1073/pnas.98.2.676,Computer_Science_easy_166,"Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work.","These decreases suggest the existence of an organized, baseline default mode of brain function that is suspended during specific goaldirected behaviors.","Therefore, Nixon doesn't try to offer a definitive answer to the question but rather a way to think about it. Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work. As Nixon notes, there needs to be much more research into the links between attention and productivity.","Defining the baseline state of an area in this manner attaches meaning to a group of areas that consistently exhibit decreases from this baseline, during a wide variety of goal-directed behaviors monitored with positron-emission tomography and functional MRI. These decreases suggest the existence of an organized, baseline default mode of brain function that is suspended during specific goaldirected behaviors. 1 and 2).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1088/1741-2552/aabc9b,Computer_Science_easy_168,"Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers.",Adaptive DBS resulted in less total energy use compared to open-loop DBS.,"Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects. Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.","Both subjects denied any awareness of changes in stimulation settings during testing sessions. Adaptive DBS resulted in less total energy use compared to open-loop DBS. For sessions using adaptive DBS during dyskinesia the total energy saved was 38% for Patient 1 using Nexus D3, and 45% and 39% for Patients 1 and 2 respectively using Nexus E. An important consideration is that there is an additional 10% battery cost associated with sensing the electrophysiology data and running the Nexus E algorithm.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1098/rstb.2008.0288,Computer_Science_easy_169,But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.,"This was true even when taxi drivers were compared with another group of navigators, London bus drivers press; see figure 3a,b).","It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place. Four years later 39 of the 79 trainees had earned their licenses; 20 trainees who failed their exams agreed to continue participating in the study.","3. This was true even when taxi drivers were compared with another group of navigators, London bus drivers press; see figure 3a,b). While their vastly superior London knowledge distinguished them, an examination of grey matter volume in the brains of taxi drivers revealed further differences.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_easy_170,"In other words, just like larger systems, small systems also tend to become more disordered.","As we will see these conditions can also be expressed in terms of smoothed entropies , however, we would like to emphasize that there are in fact only two smoothing strategies, one for α ≥ 1 and one for α < 1.","Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","More precisely, given probability distributions p and q and > 0 we can construct smoothed distributions p ∈ B (p) and q ∈ B (q) according to explicit smoothing strategies as in Lemma 25 . As we will see these conditions can also be expressed in terms of smoothed entropies , however, we would like to emphasize that there are in fact only two smoothing strategies, one for α ≥ 1 and one for α < 1. This means that one could apply these smoothing strategies, and only verify the two conditions stated above.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_171,"""We believe that the principles introduced by Poincare, which are the basis of our algorithms, could be more general and are utilized by the brain at multiple levels.","We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment.","""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said. ""We believe that the principles introduced by Poincare, which are the basis of our algorithms, could be more general and are utilized by the brain at multiple levels.","One of the most fundamental perceptual notions, space, cannot be an exception to this requirement. We show that the notion of space as environmentindependent cannot be deduced solely from exteroceptive information, which is highly variable and is mainly determined by the contents of the environment. The environment-independent definition of space can be approached by looking into the functions that link the motor commands to changes in exteroceptive inputs.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.robot.2015.01.003,Computer_Science_easy_172,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""",A first agent is introduced to show why considering only exteroception is problematic when attempting to produce a stable internal representation of spatial properties.,"These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","Next, it is shown in Section 3 how the manifold of points of view can be obtained in a more complicated case, and a discussion on the genericity of the results follows. A first agent is introduced to show why considering only exteroception is problematic when attempting to produce a stable internal representation of spatial properties. This relation specifies that, according to the physics of the world, any motor output m is associated with a sensory input s for a given environment E. Note that the sensorimotor law is of course unknown to the naive agent.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.neuroimage.2014.02.004,Computer_Science_easy_173,"The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research.","Both EOG channels were used in the regression, except for two subjects who had only one successfully functioning EOG channel.","These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions. The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research. With the help of MEG and new analysis methods, investigation of significantly faster brain processes is possible and it enables detection of brain activity in frequencies higher than before.","Eye movement and eye blink artifacts were suppressed by multiple linear regression applied to the raw MEG data after SSS procedure. Both EOG channels were used in the regression, except for two subjects who had only one successfully functioning EOG channel. M-CCA can be used to estimate matrices W m in the group so that the projections y m , i.e.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.98.2.676,Computer_Science_easy_174,"As Nixon notes, there needs to be much more research into the links between attention and productivity.",5 ).,"Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work. As Nixon notes, there needs to be much more research into the links between attention and productivity. The sharp decline in productivity after the financial crisis is what makes Nixon's line of enquiry interesting.","Understanding the exact functions served by such tonically active areas would require much additional work, yet some indication of the directions this research might profitably take is revealed by our current knowledge about two of them. 5 ). 28) .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1007/s10055-018-0346-3,Computer_Science_easy_175,"Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","In addition, the users that used the HMD first and then moved to a traditional desktop had better performance than those who used the desktop first and then the HMD.","The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better. ""This leads to the possibility that an immersive virtual environment could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" said Catherine Plaisant, Senior Research Scientist in University of Maryland Institute for Advanced Computer Studies.","However, when the target was absent, the users were able to confirm its absence faster in the HMD than on the traditional display. In addition, the users that used the HMD first and then moved to a traditional desktop had better performance than those who used the desktop first and then the HMD. This suggests a positive transfer effect from the HMD to a desktop.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1073/pnas.98.2.676,Computer_Science_easy_176,"To further develop it, he suggests empirical research on the drag to productivity from the distraction channels above, or analysis of existing data to measure the gains to productivity by firms that go to particular efforts to enhance their employees' attention, compared with similar firms that don't.","The primary issue this paper will address is whether these unexplained decreases merely arise from unrecognized increases (i.e., activation in the jargon of functional brain imaging) present only in the ''control state.''","The sharp decline in productivity after the financial crisis is what makes Nixon's line of enquiry interesting. To further develop it, he suggests empirical research on the drag to productivity from the distraction channels above, or analysis of existing data to measure the gains to productivity by firms that go to particular efforts to enhance their employees' attention, compared with similar firms that don't. This is just one way to think of the bigger issues about the relationship between new technologies and productivity.","This consistency with which certain areas of the brain participate in these decreases made us wonder whether there might be an organized mode of brain function that is present as a baseline or default state and is suspended during specific goal-directed behaviors. The primary issue this paper will address is whether these unexplained decreases merely arise from unrecognized increases (i.e., activation in the jargon of functional brain imaging) present only in the ''control state.'' Thus, on this argument, any control state, no matter how carefully it is selected, is just another task state with its own unique areas of activation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1016/j.robot.2015.01.003,Computer_Science_easy_177,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.",It can therefore be used as an internal representation of the agent's external configuration.,"If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","Thus, each set M i can be considered as a point on some new manifold. It can therefore be used as an internal representation of the agent's external configuration. Note that to obtain this internal representation the agent does not have to assume the existence of space: it simply has to associate the motor commands resulting in the same sensory input with each other.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1145/2872427.2883081,Computer_Science_easy_178,"This implies that the persuader is already open-minded and aware of their own biases, which is important.","The use of more paragraphs, bold formatting, and bulleted lists are all higher when a malleable view is expressed.","When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant. This implies that the persuader is already open-minded and aware of their own biases, which is important. I think it is safe to say that most Americans, regardless of political affilitation, want what is best for America.","Our result aligns with these findings: individualizing one's relationship with a belief using first person pronouns affirms the self, while first person plurals can indicate a diluted sense of group responsibility for the view. The use of more paragraphs, bold formatting, and bulleted lists are all higher when a malleable view is expressed. Taking more time and presenting the reasons behind an opinion in a more elaborated form can indicate more engagement.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1016/j.compag.2016.07.028,Computer_Science_easy_179,"I think that's the beauty of this phenotyping that wasn't really possible in the past.""",This can be attributed to two reasons.,"We can analyze the growth rate and look at the changes over time at different developmental stages. I think that's the beauty of this phenotyping that wasn't really possible in the past."" Achieving that level of specificity might allow it to recognize and track those same components across changes in appearance and location, an important consideration for a plant that develops as quickly and dynamically as corn.","It can be seen that, when modeled separately, B73 gives better prediction accuracy than FFMM-A. This can be attributed to two reasons. First, at late stage of the experiment, FFMM-A plants appear to be bushier than B73 (Supplemental Fig.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1007/978-3-642-55220-5_1,Computer_Science_easy_180,"Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc.","This can be used to solve certain discrete logarithms in, say, F 2 n for adequately chosen n (much similar to records tackled by ).","It discredits several cryptographic systems that until now were assumed to provide sufficient security safeguards. Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc. The algorithm they devised stands out from the best algorithms known to date for this problem.","Much the same can be said in the case where n is composite and factors nicely, so that F Q admits a large enough subfield F q with q = p m . This can be used to solve certain discrete logarithms in, say, F 2 n for adequately chosen n (much similar to records tackled by ). While we have seen that Corollary 4 can be used to treat some cases, its applicability might be hindered by the absence of an appropriately sized subfield: p might be as small as 2, and n might not factor adequately.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_181,"Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment.",It should not be possible to represent a manifold associated with an object configuration on the plane (two translational coordinates and orientation angle) in 3D because of the circularity involved in orientation.,"If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves."" Terekhov and his colleagues showed that the notion of space as environment-independent cannot be deduced only by exteroceptive information, as this information varies greatly depending on what is found in the environment. This notion could be better defined by looking into functions that link motor commands to changes in stimuli that are external to the agent.","Furthermore, it is important to remark that the internal manifold generated in the last experiment can only be visualized because the size of the agent's working space is limited. It should not be possible to represent a manifold associated with an object configuration on the plane (two translational coordinates and orientation angle) in 3D because of the circularity involved in orientation. The use of a limited working space allows the manifold to be strongly deformed during the projection in 3D to take the circular dimension into account while avoiding any self-collision.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_183,"Well, yeah, if you subject them to high temperatures.","While adding glucose increases browning, it can decrease the production of mutagens .","High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures. Most sous vide cooking temperatures are below 190 degrees F (87.8 degrees C), so you shouldn't need to worry about melting.","• F) roughly doubles the quantity of mutagens . While adding glucose increases browning, it can decrease the production of mutagens . The type of fat used to sear the meat in a pan has only minor effects on the formation of mutagens, but the pan residue using butter was significantly higher in mutagens than when using vegetable oil .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_184,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was.","Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90","aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.","). Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90 • C/195",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1177/1080569913501862,Computer_Science_easy_185,Higher-income professionals had less tolerance for smartphone use in business meetings.,The intensity of these comments was stronger when talking about what managers do.,"Despite the casual reputation, professionals from the West Coast were less accepting of mobile phone use in meetings than people from the East Coast. Higher-income professionals had less tolerance for smartphone use in business meetings. Dramatic age gap: Younger professionals were nearly three times as likely as older professionals to think tapping out a message over a business lunch is appropriate -- 66 percent of people under 30 said texting or emailing was okay, compared to just 20 percent of those aged 51-65.","Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive."" The intensity of these comments was stronger when talking about what managers do. Table 3 shows the perceived appropriateness of these various mobile phone behaviors during formal meetings at the workplace.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1411728112,Computer_Science_easy_188,The results of the study give an improved understanding of how heat and energy is transformed on very small scales.,"Finally, in case (iii), if we consider the transition p → q, with a small amount of work invested in addition:","For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly."" The results of the study give an improved understanding of how heat and energy is transformed on very small scales.","So again already the conditions with α > 0 report the impossibility of transition, and negative α's are not needed. Finally, in case (iii), if we consider the transition p → q, with a small amount of work invested in addition: , 0) k (equivalently, a pure state on C k ) and η k stands for the uniform distribution with k elements.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_189,"High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with.",• C/194,"A little research on the company's website should tell you what the bags are made of. High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures.",• F ; FDA (2011) gives a more conservative time of 10 minutes at 90 • C/194 • F with z = 7.0 • C/12.6,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1073/pnas.1411728112,Computer_Science_easy_191,"""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""",The statistical distance between p and p is,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average.","Now, let us consider the set Z δ = {i : pi qi ≥ δ}. The statistical distance between p and p is note that d can be made equal to , by tuning δ in a continuous manner.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_192,"Initially, the mind-controlled limb had an accuracy of 76 percent.","The decoding results were significantly better than the estimation results when evaluated with the PER metric for all subject sets (Wilcoxon, < -p 10 11 ).","""This precision is what allowed us to separate the control of individual fingers."" Initially, the mind-controlled limb had an accuracy of 76 percent. Once the researchers coupled the ring and pinkie fingers together, the accuracy increased to 88 percent.","All of the HGW results were significantly better than the HGS results for all subject sets and metrics (Wilcoxon, < p 0.005). The decoding results were significantly better than the estimation results when evaluated with the PER metric for all subject sets (Wilcoxon, < -p 10 11 ). Similarly, confusion accuracies were significantly better for decoding results than for estimation results (Wilcoxon, < p 0.01) for all evaluations except the ones using averaged HGWs from subject C and concatenated HGWs.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1016/j.neuroimage.2014.02.004,Computer_Science_easy_193,"These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions.","1 shows the results for 0.03-1 Hz, 1-5 Hz and 5-10 Hz frequency bands.","""The analysis revealed important similarities between brain signals of different people during movie viewing. These similar kinds or synchronized signals were found in brain areas that are connected with the early-stage processing of visual stimuli, detection of movement and persons, motor coordination and cognitive functions. The results imply that the contents of the movie affected certain brain functions of the subjects in a similar manner,"" explains Kaisu Lankinen the findings of her doctoral research.","However, the first canonical variate of 12 Hz survived the significance testing with intersubject correlation of 0.053 ± 0.055 (mean ± SD). 1 shows the results for 0.03-1 Hz, 1-5 Hz and 5-10 Hz frequency bands. The highest statistically significant inter-subject correlations (0.28 ± 0.075; p b 0.05, correlation N 0.053, Bonferroni corrected), were observed in the lowest 0.03-1 Hz band (with the first canonical variates) where correlations for 5 out of the 68 canonical variates exceeded the statistical threshold (dashed line).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140407090615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.98.2.676,Computer_Science_easy_194,"Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work.",This consistency with which certain areas of the brain participate in these decreases made us wonder whether there might be an organized mode of brain function that is present as a baseline or default state and is suspended during specific goal-directed behaviors.,"Therefore, Nixon doesn't try to offer a definitive answer to the question but rather a way to think about it. Meanwhile, the influx of emails, calls, and instant messages at work could be reducing our IQ and lowering the quality of our work. As Nixon notes, there needs to be much more research into the links between attention and productivity.","1 ) appear to be largely task independent, varying little in their location across a wide range of tasks (3). This consistency with which certain areas of the brain participate in these decreases made us wonder whether there might be an organized mode of brain function that is present as a baseline or default state and is suspended during specific goal-directed behaviors. The primary issue this paper will address is whether these unexplained decreases merely arise from unrecognized increases (i.e., activation in the jargon of functional brain imaging) present only in the ''control state.''",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1073/pnas.1411728112,Computer_Science_easy_195,"Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.",[36] ).,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.",for α ≤ γ (see Theorem 3 of Ref. [36] ). Explicitly we have,[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_197,"McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor.","• C as per ), but this isn't a critical control point: While C. perfringens does produce toxins, it only produces them while sporulating (and so isn't a concern when heating) and the toxin is easily destroyed by heating (since it's destroyed in only 10 minutes at 60","The chicken was still very tough; the residual taste in my mouth still very strong. McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor. McNuggets are preserved enough to sustain themselves through an apocalypse and still taste like theyare fresh out of the fryer.","Many recommend that the core of the food reach 54.4 • C as per ), but this isn't a critical control point: While C. perfringens does produce toxins, it only produces them while sporulating (and so isn't a concern when heating) and the toxin is easily destroyed by heating (since it's destroyed in only 10 minutes at 60 • C/ 140",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_198,"Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","W can be either negative or positive, depending on whether work is used from or stored in the battery system.","""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","This prompts our definition of the work distance below. W can be either negative or positive, depending on whether work is used from or stored in the battery system. This means that the following transition is possible",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_199,"""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","In fact, we will see that the second laws impose a constraint on how one defines work, if one demands reversibility of the work system.","The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average.","However, as the work system is an ancilla, one needs to check that this universality continues to hold in the context where catalysts are allowed. In fact, we will see that the second laws impose a constraint on how one defines work, if one demands reversibility of the work system. We see that this is satisfied when work is defined in terms of raising and lowering the energy of a pure state (or a system with highly peaked energy).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_200,"""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","Here, we show that this is not the case in the microscopic regime, and we therefore needs to talk about ""how cyclic"" a process is when stating the second law.","In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","What's more, one needs to be more precise about what one means by a cyclic process. Here, we show that this is not the case in the microscopic regime, and we therefore needs to talk about ""how cyclic"" a process is when stating the second law. We also derive in this work, a zeroeth law of thermodynamics, which is stronger than the ordinary zeroeth law.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_201,could be instilled in biological or artificial systems.,"The first and most basic property of those laws is an invariance: space does not depend on the particular environment, nor on the particular posture of the agent.","a) 1% of the 2500 exploratory arm configurations mi . could be instilled in biological or artificial systems. ""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to.","It can be identified in the laws that govern the way sensory inputs change as the agent moves around. The first and most basic property of those laws is an invariance: space does not depend on the particular environment, nor on the particular posture of the agent. The agent must somehow know that its sensor is at the same spatial position independently of what objects are around and what are the positions of the other sensors.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1411728112,Computer_Science_easy_202,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","Either from the very definition or from the above characterization one sees that given any non-passive state ρ np , one can extract on average a non-zero amount of work by performing a population inversion (a switch of energy levels).","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","They proved for general quantum systems described by a C * algebra that the only completely passive states are either so called KMS states or ground states. Either from the very definition or from the above characterization one sees that given any non-passive state ρ np , one can extract on average a non-zero amount of work by performing a population inversion (a switch of energy levels). By invoking typicality arguments, we show that by performing extraction over many identical copies of ρ np , an amount of work closely related to average work can always be extracted except with small probability.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_204,"But we found them within the five years it took to do the study.""","This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification.","""Maybe they only appeared quite some time after the trainees qualified. But we found them within the five years it took to do the study."" He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain.","In particular, the correlations between time taxi driving and hippocampal grey matter volume suggest that experience drives the patterns observed. This longitudinal approach will also permit the examination of the characteristics of those who succeed at taxi driver training, and whether innate pre-training cognitive factors and/or hippocampal volume are predictive of subsequent successful qualification. This will provide vital information about brain plasticity and navigation expertise, and the factors that might affect or limit the ability to develop such expertise.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_205,"Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results.",Note that found that fish cooked sous vide retains more healthful omega-3 fatty acids and nutrients than traditionally cooked fish.,"Still, though, I had some lingering questions about their safety. Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results. That may be so, but it isn't any more likely than with vacuum bags designed for sous vide cooking -- they are made out of the exact same kind of plastic.","• C/ 38 Note that found that fish cooked sous vide retains more healthful omega-3 fatty acids and nutrients than traditionally cooked fish. Sous vide cooked vegetables, in comparison, retain nearly all their nutritive value ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1073/pnas.1411728112,Computer_Science_easy_206,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.",We prove this in Sections F and E of the Supplementary Information.,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","Not only do these second laws provide limitations, but they are also sufficient -whenever the free energies of one state are all greater than for the other state, one can transform the one into the other one. We prove this in Sections F and E of the Supplementary Information. Note that the monotonicity of (2) establishes a continuous family of conditions, one for each value of α.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/s10055-018-0346-3,Computer_Science_easy_207,"The questionnaire also found that only two people said they felt ""uncomfortable"" using VR.","This was shown to be statistically significant using a paired t test with Bonferroni-Holm correction with p = 0.0062 < 0.05 , which reinforces that participants in the HMD had better recall than those on the desktop.","In post-study questionnaires, all 40 participants said that they were completely comfortable -- and adept -- in navigating a desktop computer to access information, yet all but two said they preferred the immersive VR environment as a potential learning platform. The questionnaire also found that only two people said they felt ""uncomfortable"" using VR. Many of the participants said the immersive ""presence"" while using VR allowed them to focus better.","7 , we showed that the number of faces for which participants skipped an answer in the desktop condition was significantly higher than in the HMD condition. This was shown to be statistically significant using a paired t test with Bonferroni-Holm correction with p = 0.0062 < 0.05 , which reinforces that participants in the HMD had better recall than those on the desktop. 8 , we can see that users were slightly more confident in the HMD condition than on the desktop condition.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1007/s10055-018-0346-3,Computer_Science_easy_208,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","Our user study is highly influenced by the study of , but in our study, users perform recall rather than search.","They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality. The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number.","This suggests a positive transfer effect from the HMD to a desktop. Our user study is highly influenced by the study of , but in our study, users perform recall rather than search. They found that the users wearing the HMD had faster navigation times and less waste-full movement and were more accurately able to estimate distances, compared to those using a desktop.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1073/pnas.1411728112,Computer_Science_easy_209,"They showed that not only does entropy increase, but other types of disorder also have to increase.",(ii) p has less zeros than q.,"The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder. They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails.","We have three cases (i) p has more zeros than q. (ii) p has less zeros than q. (iii) p and q have the same number of zeros (in particular, can both have no zeros).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.compag.2016.07.028,Computer_Science_easy_210,"The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers.","It is quite likely that this technique can be extended to quantify plant chemical phenotypes including nitrogen content, photopigment concentration, and mineral content.","The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers. The crop's unwieldy size and complex anatomy have left it mostly ignored by previous automated phenotyping work, the researchers said. We were fairly successful in doing that.""","Data points were missing on DAS 22 due to an unexpected disruption of the automated imaging routine on that day. It is quite likely that this technique can be extended to quantify plant chemical phenotypes including nitrogen content, photopigment concentration, and mineral content. The major conclusions drawn from this study are:",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1098/rspb.2019.0646,Computer_Science_easy_211,"Turns out, it's all about psychology.","These ideas may be of importance in further understanding the evolution of imperfect camouflage; for example, future research could consider whether there are differences in predator search image formation ability for generalist and specialist strategies .","When it comes to choosing a mate, female guppies often go for the mates with the flashiest, most interesting color patterns. Turns out, it's all about psychology. In other words, the female guppy is often immune to the charms of a male guppy that looks like all the other male guppies.","Studying how camouflage evolves in heterogeneous habitats also has important consequences for the understanding of the development and maintenance of polymorphism. These ideas may be of importance in further understanding the evolution of imperfect camouflage; for example, future research could consider whether there are differences in predator search image formation ability for generalist and specialist strategies . The study of imperfect camouflage also has parallels with imperfect mimicry.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1177/1080569913501862,Computer_Science_easy_212,Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable.,The intensity of these comments was stronger when talking about what managers do.,"Even at more informal business lunches, the majority of people thought writing a text message is rude -- 66 percent said writing or sending a text message is inappropriate. Men were nearly twice as likely as women to consider mobile phone use at a business lunch acceptable. More than 59 percent of men said it was okay to check text messages at a power lunch, compared to 34 percent of women who thought checking texts was appropriate.","Many professionals used phrases such as ""people are so inconsiderate,"" ""disrespectful mobile phone usage is everywhere,"" and ""it is very disruptive."" The intensity of these comments was stronger when talking about what managers do. Table 3 shows the perceived appropriateness of these various mobile phone behaviors during formal meetings at the workplace.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131024182551.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_213,"They didn't melt, burn or make me sick.",• C/150,"I have never had a problem with them. They didn't melt, burn or make me sick. Still, though, I had some lingering questions about their safety.","• C/120 • C/150 • F. While this increase in tenderness used to be attributed to a weakening of connective tissue, most now believe it's caused by the change from a viscoelastic to an elastic material: raw meat is tougher because of the viscous flow in the fluid-filled channels between the fibers and fiber bundles; heating up to 65",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_214,"McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions.","Cooking in heat-stable, vacuumized pouches improves shelf-life and can enhance taste and nutrition.","In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game. McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions. Fresh, free of antibiotics and all the other buzzwords give it the advantage here.","Precise temperature control gives more choice over doneness and texture than traditional cooking methods. Cooking in heat-stable, vacuumized pouches improves shelf-life and can enhance taste and nutrition. Vacuum-sealing has several benefits: it allows heat to be efficiently transferred from the water (or steam) to the food; it increases the food's shelf-life by eliminating the risk of recontamination during storage; it inhibits off-flavors from oxidation and prevents evaporative losses of flavor volatiles and moisture during cooking ; and reduces aerobic bacterial growth -this results in especially flavorful and nutritious food .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1145/2872427.2883081,Computer_Science_easy_216,"While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","Nevertheless, it yields an interesting insight: comparative adjectives and Figure 9 : Opinion malleability prediction performance: AUC on the heldout dataset.","While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them. ADVERTISEMENT

When you engage Trump loyalists in debate, try to respond with meaty content that has greater numbers of sentences and paragraphs, since research shows that one-liners and superficial statements do little to persuade people.","The POS classifier significantly outperforms random guessing, but not the baseline. Nevertheless, it yields an interesting insight: comparative adjectives and Figure 9 : Opinion malleability prediction performance: AUC on the heldout dataset. The BOW and all feature sets perform significantly better than the #words baseline, according to one-sided paired permutation tests.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1007/978-3-642-55220-5_1,Computer_Science_easy_217,"Not only is it significantly easier to explain, but its complexity is also considerably improved.","For the limiting case L(1/3, c), the Function Field Sieve remains more efficient for small values of c, and the Number Field Sieve is better for large values of c (see ).","The algorithm they devised stands out from the best algorithms known to date for this problem. Not only is it significantly easier to explain, but its complexity is also considerably improved. This means that it is able to solve increasingly large discrete logarithm problems, while its computing time increases at a far slower rate than with previous algorithms.","Whenever α < 1/3, our new algorithm offers the smallest complexity. For the limiting case L(1/3, c), the Function Field Sieve remains more efficient for small values of c, and the Number Field Sieve is better for large values of c (see ). K is isomorphic to F q 2k with k ≥ 1; -there exist two polynomials h 0 and h 1 over F q 2 of small degree, such that",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s12911-017-0526-1,Computer_Science_easy_218,"/ no comments

Medicine, Health Care UVA Aims to Help Patients...","In general, stakeholders indicated that privacy considerations did not present significant barriers to the proposed decision aid framework, partly due to an understood distinction between tumor genomics versus an individual patient's germline genetic information.","/ no comments

Medicine, Health Care UVA Aims to Help Patients... And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information. The stakeholders - 22 in all - concluded that patients need a way to compare the treatment options in a fashion personalized for them, incorporating factors such as age, personal priorities, genomics-defined risk of cancer recurrence and other health conditions.","The majority of suggestions from all stakeholder groups focused on aspects of decision aid design and formatting, as well as delivery location/context and access to the decision aid, with the least time in discussion focusing privacy concerns. In general, stakeholders indicated that privacy considerations did not present significant barriers to the proposed decision aid framework, partly due to an understood distinction between tumor genomics versus an individual patient's germline genetic information. Regarding location and context of decision aid delivery, a common theme was that stakeholders felt information should be disseminated across multiple platforms and should be available both before and during consult appointments.",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/uva-aims-to-help-patients-with-cancer-make-complex-care-decisions/
10.1098/rstb.2008.0288,Computer_Science_easy_220,"That's a big deal.""","However, we would argue that the potential costs of expertise also warrant consideration.","""But it turns out it really was the training process that caused the growth in the brain. It shows you can produce profound changes in the brain with training. That's a big deal.""","This was attributed to their musical sight-reading and motor sequencing expertise. However, we would argue that the potential costs of expertise also warrant consideration. We found that the hippocampus is not required for general orientation in the city, detailed topographical knowledge of landmarks and their spatial relationships, or even for the navigation along some routes, all of which abilities were preserved.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_221,I have never had a problem with them.,"• C/31.3 • F and 5 FDA, 2011; .","I have never had a problem with them. They didn't melt, burn or make me sick. Still, though, I had some lingering questions about their safety.","If the food was pasteurized for the Salmonella species instead of L. monocytogenes then the growth of Listeria limits shelf-life to less than 7 days between −0.4 • C/31.3 • F and 5 FDA, 2011; . (2006); ; ; .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1007/978-3-642-55220-5_1,Computer_Science_easy_222,This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.,"These results are summarized in table 1, where the last column omits small prime factors below q 2 .","Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","Again, the only prime factors appearing in the GCDs were either originating from the factorization of q 3 − q, or sporadically from the birthday paradox. These results are summarized in table 1, where the last column omits small prime factors below q 2 . Of course, we remark that considering square submatrices is a more demanding check than what Heuristic 7 suggests, since our algorithm only needs a slightly larger matrix of size Θ(q 3 ) × (q 2 + 1) to have full rank.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1088/1741-2552/aabc9b,Computer_Science_easy_223,The device differs from traditional ones in that it can both monitor and modulate brain activity.,"The narrowband gamma signal related to dyskinesia occurs at half the stimulation frequency, when dyskinesia is present ( Figure 1A and 1C) .","The new method described in this study is adaptive, so that the stimulation delivered is responsive in real time to signals received from the patient's brain. The device differs from traditional ones in that it can both monitor and modulate brain activity. Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects.","(For instance, constant current was not used for algorithm prototyping due to artifacts associated with this mode .) The narrowband gamma signal related to dyskinesia occurs at half the stimulation frequency, when dyskinesia is present ( Figure 1A and 1C) . Stimulation parameters used for adaptive DBS are shown in",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1073/pnas.1411728112,Computer_Science_easy_224,The results of the study give an improved understanding of how heat and energy is transformed on very small scales.,5).,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly."" The results of the study give an improved understanding of how heat and energy is transformed on very small scales.","Note however, that we can rule out negative α in a different way, if instead of insisting on preparing exact output state, we allow for preparing an ε-approximation, with arbitrary accuracy (as discussed in Prop. 5). Therefore, in case (iii) considered above we can add to both sides an ancilla in a pure state of the same dimension (which is actually needed only when p and q both have no zeros).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_225,"That's a big deal.""","2006a, Woollett & Maguire in press) , control non-taxi drivers were significantly better on the delayed recall of the Rey Figure than the fulltime taxi drivers.","""But it turns out it really was the training process that caused the growth in the brain. It shows you can produce profound changes in the brain with training. That's a big deal.""","Figure 6c shows that, as in our previous studies (Maguire et al. 2006a, Woollett & Maguire in press) , control non-taxi drivers were significantly better on the delayed recall of the Rey Figure than the fulltime taxi drivers. Interestingly, there was no significant difference between the controls and the retired taxi drivers.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_easy_226,"They showed that not only does entropy increase, but other types of disorder also have to increase.","Considering such resources are crucial, since the experimenter who is trying to extract work or otherwise manipulate a system, should be allowed as much ingenuity as possible.","The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder. They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails.","This paradigm is equivalent to ones in which we allow interaction Hamiltonians rather than unitaries, or where we allow for a Hamiltonian which changes with time, provided that all ancillas are carefully accounted for [ . Considering such resources are crucial, since the experimenter who is trying to extract work or otherwise manipulate a system, should be allowed as much ingenuity as possible. In essence, how cyclic a process is can be understood in terms of how good an approximation ρ in C is to ρ out C .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2552/aabc9b,Computer_Science_easy_227,The device differs from traditional ones in that it can both monitor and modulate brain activity.,Adaptive DBS resulted in less total energy use compared to open-loop DBS.,"The new method described in this study is adaptive, so that the stimulation delivered is responsive in real time to signals received from the patient's brain. The device differs from traditional ones in that it can both monitor and modulate brain activity. Stimulation was reduced when it identified dyskinesia-related brain activity and increased when brain sensing indicated no dyskinesia to minimize deep brain stimulation-related side effects.","Both subjects denied any awareness of changes in stimulation settings during testing sessions. Adaptive DBS resulted in less total energy use compared to open-loop DBS. For sessions using adaptive DBS during dyskinesia the total energy saved was 38% for Patient 1 using Nexus D3, and 45% and 39% for Patients 1 and 2 respectively using Nexus E. An important consideration is that there is an additional 10% battery cost associated with sensing the electrophysiology data and running the Nexus E algorithm.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1145/2872427.2883081,Computer_Science_easy_228,"It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now.","For posts where the OP gave at least one delta, the OP gave 1.5 deltas on average.","It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now. From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation. But completely giving up on the task of converting fellow Americans--even staunch Trump supporters and outlandish conspiracy theorists--into crusaders for logic and reason should not be an option.","Monthly trends are depicted in Figure 3: 7 after the initial startup, activity levels stabilize to a healthy, stable growth in average number of replies and challengers, as, gratifyingly, do OP conversion rates, computed as the fraction of discussion trees wherein the OP awarded a ∆ (Figure 3d ). For posts where the OP gave at least one delta, the OP gave 1.5 deltas on average. A late entry might give the challenger time to read attempts by other challengers and better formulate their arguments, while an early entry might give her the first-mover advantage.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34828472692&p=1pl&v=1&x=4ruYvZS5w6QcN2Gi21xOEg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_230,"Still, though, I had some lingering questions about their safety.",Starchy vegetables can be cooked at the slightly lower temperature of 80,"They didn't melt, burn or make me sick. Still, though, I had some lingering questions about their safety. Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results.",• C/122 Starchy vegetables can be cooked at the slightly lower temperature of 80 • C/175,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.robot.2015.01.003,Computer_Science_easy_231,"As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans.",We believe that what characterizes space is the particular structure that it imposes on possible sensorimotor experiences.,"""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to. As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans. Probably none of these.","However, these examples clearly do not correspond to what we usually mean by space. We believe that what characterizes space is the particular structure that it imposes on possible sensorimotor experiences. It can be identified in the laws that govern the way sensory inputs change as the agent moves around.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1088/1741-2552/aabc9b,Computer_Science_easy_232,"They had the same clinical benefits with pretty significant energy savings.""","In contrast, our approach utilizes an ECoG signal for feedback control, provides a higher amplitude signal that is much further from the source of stimulation artifact and does not limit the choice of DBS contacts available for stimulation (given the inability to record and stimulate from the same contact).","""We found we could do it without any negative effects in the patients. They had the same clinical benefits with pretty significant energy savings."" It works well, but with limitations,"" Swann says.","Furthermore, as we showed in our previous paper, the cortical signal was associated with an area under the curve value of 0.912 from a receiver operator curve analysis, compared to a value of 0.9 for STN . In contrast, our approach utilizes an ECoG signal for feedback control, provides a higher amplitude signal that is much further from the source of stimulation artifact and does not limit the choice of DBS contacts available for stimulation (given the inability to record and stimulate from the same contact). This last point bears particular consideration since often the contacts in STN which best detect signatures related to symptoms are also the contacts which correspond to the regions of STN most likely to be targeted for clinical use 1 .",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1287/mnsc.2016.2500,Computer_Science_easy_233,"The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says.","That is, when the flights encounter departure delays, the implementation of two checked bag fees has triggered an additional increase in SpAdj-Departure-Delay relative to the implementation of only one checked bag fees of 1.0672 minutes.","The number of baggage-related complaints per 1,000 passengers dropped as airlines' departure delay performance improved once most charged for checked bags. The findings likely open the door for future research on how the unbundling of airline services influences the performance of their operations, Arikan says. Southwest offers the most bundled services among major airlines as it offers the fewest instances of charging customers beyond their tickets.","The coefficient for the Bag-Fee variable which indicates the one checked bag fee as being implemented, is negative and marginally significant (-0.4443; p<0.1), whereas the coefficient for the Bag-Fee variable corresponding to implementing two checked bag fees, is positive and statistically significant (0.6229; p<0.05). That is, when the flights encounter departure delays, the implementation of two checked bag fees has triggered an additional increase in SpAdj-Departure-Delay relative to the implementation of only one checked bag fees of 1.0672 minutes. We reject Hypothesis 2A as we find support for Hypothesis 2B.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/airplanes-baggage-fees-1234212-2/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_236,"Well, yeah, if you subject them to high temperatures.",• C/175,"High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures. Most sous vide cooking temperatures are below 190 degrees F (87.8 degrees C), so you shouldn't need to worry about melting.",Starchy vegetables can be cooked at the slightly lower temperature of 80 • C/175 ).,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1073/pnas.1411728112,Computer_Science_easy_237,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions.","It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","In particular, we find a family of free energies which generalise the traditional one, and show that they can never increase. The ordinary second law just corresponds to the non-increasing of one of these free energies, with the remainder imposing additional constraints on thermodynamic transitions. We further find that there are three regimes which determine which family of second laws govern state transitions, depending on how cyclic the process is.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_238,He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain.,"Navigational accuracy can be supported by different types of representation, for example remembering individual routes versus a coherent map-like representation ).","But we found them within the five years it took to do the study."" He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","Even then, further questions will remain, which must be addressed in future studies. Navigational accuracy can be supported by different types of representation, for example remembering individual routes versus a coherent map-like representation ). It may be that some individuals have an innate bias for using one type of representation, with successful taxi drivers perhaps more likely to use map-like strategies.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_easy_239,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","So again already the conditions with α > 0 report the impossibility of transition, and negative α's are not needed.","Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","In case (ii) the transition cannot be realised, but this is reported by comparing ranks, which can be obtained using H 0 = lim α→0 + H α . So again already the conditions with α > 0 report the impossibility of transition, and negative α's are not needed. Finally, in case (iii), if we consider the transition p → q, with a small amount of work invested in addition:",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_240,"Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do.","• C/31.3 • F and 5 FDA, 2011; .","aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.","If the food was pasteurized for the Salmonella species instead of L. monocytogenes then the growth of Listeria limits shelf-life to less than 7 days between −0.4 • C/31.3 • F and 5 FDA, 2011; . (2006); ; ; .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_242,"High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with.",notes that at 49,"A little research on the company's website should tell you what the bags are made of. High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with. Well, yeah, if you subject them to high temperatures.",• F can significantly improve tenderness. notes that at 49 • C/120,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_243,"McNuggets, on the other hand, are perfect in both taste and consistency.","When cooking tender meats, it's the fast changes that are the most important because the slow changes are mainly used to increase tenderness.","But the seasoning kills any appeal, as does the lack of sauce options for those who need it. McNuggets, on the other hand, are perfect in both taste and consistency. And no matter how long they may or may not remain in a refrigerator before being reheated, they taste as if youave just ordered them.","While cooking times are longer than traditional cooking methods, the meat comes up to temperature surprisingly quickly because the thermal conductivity of water is 23 times greater than that of air. When cooking tender meats, it's the fast changes that are the most important because the slow changes are mainly used to increase tenderness. Thus, for tender meat you just need to get the center up to temperature and, if pasteurizing, hold it there until any pathogens have been reduced to a safe level.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_244,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was.",• C/185,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.",• C/167 • C/185 • F ; FDA (2011) gives a more conservative time of 10 minutes at 90,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_245,"The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","Motor fluctuations in patients in this pilot study were less extreme, which may explain why adaptive DBS in this short-term study did not show therapeutic superiority over open-loop continuous DBS.","Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods. ""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal.""","While for some patients simply manually adjusting their own DBS settings might be sufficient to avoid frequent dyskinesia, for others, especially patients with very frequent motor fluctuations, such an approach would be cumbersome and imprecise. Motor fluctuations in patients in this pilot study were less extreme, which may explain why adaptive DBS in this short-term study did not show therapeutic superiority over open-loop continuous DBS. Indeed, it is possible there could have been a floor effect for dyskinesia in this study since dyskinesia was mild for all conditions (see Table 3 ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1007/s10055-018-0346-3,Computer_Science_easy_246,"""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality.","The authors found that users, when using their physical loci technique, had superior command recall and were more robust compared to the more traditional mid-air swipe menu.","They found that people remember information better if it is presented to them in a virtual environment. ""This data is exciting in that it suggests that immersive environments could offer new pathways for improved outcomes in education and high-proficiency training,"" said Amitabh Varshney, Professor of Computer Science, in a survey published in the journal Virtual Reality. The results showed an 8.8 per cent improvement overall in recall accuracy using the VR headsets, a statistically significant number.","In our study, we expect vestibular and proprioceptive inputs to improve performance in the HMD. The authors found that users, when using their physical loci technique, had superior command recall and were more robust compared to the more traditional mid-air swipe menu. This study is different from the previous work in several ways.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34313063783&p=1pl&v=1&x=TCex6cBLjKUBpfnsnX7wYA
10.1016/j.robot.2015.01.003,Computer_Science_easy_248,"However, if we move 10 cm left, the image we see will remain almost exactly the same.",The authors would like to thank anonymous reviewers for their useful comments contributing towards better positioning and clarity of the manuscript.,"The ideas introduced by Poincare can be better explained with a simple example. However, if we move 10 cm left, the image we see will remain almost exactly the same. ""This property seems miraculous if you think about how many receptors the human body has,"" Terekhov said.",The final structure captured by the agent will thus be closer to what we intuitively expect from a notion of space. The authors would like to thank anonymous reviewers for their useful comments contributing towards better positioning and clarity of the manuscript. The rotary nature of the arm's actuators implies that the manifold M i is closed.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.98.2.676,Computer_Science_easy_249,"To further develop it, he suggests empirical research on the drag to productivity from the distraction channels above, or analysis of existing data to measure the gains to productivity by firms that go to particular efforts to enhance their employees' attention, compared with similar firms that don't.",This observation is consistent with the hypothesis that the baseline state of these areas is more nearly approximated when subjects rest quietly with their eyes open.,"The sharp decline in productivity after the financial crisis is what makes Nixon's line of enquiry interesting. To further develop it, he suggests empirical research on the drag to productivity from the distraction channels above, or analysis of existing data to measure the gains to productivity by firms that go to particular efforts to enhance their employees' attention, compared with similar firms that don't. This is just one way to think of the bigger issues about the relationship between new technologies and productivity.",4) increase their BF when the eyes are opened (details to be published separately). This observation is consistent with the hypothesis that the baseline state of these areas is more nearly approximated when subjects rest quietly with their eyes open. Our study represents a comprehensive analysis of the uniformity of the OEF in the normal human brain while adult subjects are awake and resting quietly with their eyes closed.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1073/pnas.1411728112,Computer_Science_easy_252,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.",", 1/N ) the uniform distribution.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","with η N = (1/N, . , 1/N ) the uniform distribution. By (E10), this means that equivalently",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_253,"As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans.","By searching only for displacements or, in sensorimotor terms, transformations that both the agent and objects in the environment can perform, it should be possible to avoid capturing such non-spatial degrees of freedom.","""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to. As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans. Probably none of these.","Such a non-spatial degree of freedom would be captured without distinction by our method, increasing the dimensionality of the internal manifold. By searching only for displacements or, in sensorimotor terms, transformations that both the agent and objects in the environment can perform, it should be possible to avoid capturing such non-spatial degrees of freedom. The final structure captured by the agent will thus be closer to what we intuitively expect from a notion of space.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1145/2872427.2883081,Computer_Science_easy_254,"While this task can certainly be difficult, the good news is that it is by no means impossible.","From the perspective of an original post, conversion can happen when any of the challengers participating in the discussion succeeds in changing the OP's view.","If you consider yourself a good Samaritan, such an effort should be considered a moral responsibility and an ethical imperative. While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","We observe a non-monotonic relation between back-and-forth engagement and likelihood of success: perhaps while some engagement signals the interest of the OP, too much engagement can indicate futile insistence; in fact, after 5 rounds of back-and-forth the challenger has virtually no chance of receiving a ∆. From the perspective of an original post, conversion can happen when any of the challengers participating in the discussion succeeds in changing the OP's view. It is reasonable to expect that an OP's conversion is tied to the number of challengers .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1098/rstb.2008.0288,Computer_Science_easy_255,"Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others.","It may be that with a longer period of retirement, performance on tests such as the Rey Figure would normalize entirely.","The successful trainees did not perform better on all tests of memory, however. Maguire thinks that The Knowledge may enlarge the hippocampus's posterior (rear) at the expense of its anterior (front), creating a trade-off of cognitive talents--that is, taxi drivers master some forms of memory but become worse at others. She didn't find this same difference in her new study because, she speculates, front-end shrinkage may happen after the four years of training.","The intermediate performance of the retired taxi drivers, not as poor as the full-timers, and not as good as controls, is in line with the view that ceasing to use a skill might result in the normalization of expertise-related negative outcomes. It may be that with a longer period of retirement, performance on tests such as the Rey Figure would normalize entirely. In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_257,"The skin, which offers a slight crunch when prepared perfectly, is the best part.",• C/131 • F and 60,"Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part. The meat is light, a little salty and, of course, very greasy.",At lower temperatures (50 found that tough cuts of beef (from animals 0-4 years old) were the most tender when cooked to between 55 • C/131 • F and 60 • C/140 • F. Cooking the beef for 24 hours at these temperatures significantly increased its tenderness (with shear forces decreasing 26%-72% compared to 1 hour of cooking).,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_258,"This adaptation of the stimulation is the advance we are trying to make with brain stimulation.""",This signature is associated with dyskinesia that occurs following medication alone and also dyskinesia which occur during DBS .,"""Today's devices are much like cardiac pacemakers were a long time ago. This adaptation of the stimulation is the advance we are trying to make with brain stimulation."" Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation.",Neural signatures may be detected in the motor cortex as well as the basal ganglia. This signature is associated with dyskinesia that occurs following medication alone and also dyskinesia which occur during DBS . It is not strongly modulated by voluntary movement and is distinct from the canonical broadband gamma changes that occur in motor cortex during voluntary movement.,[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_260,Chickan Bites from Shake Shack donat microwave well.,• C/150,"McDonaldas, because theyare more delicious. Chickan Bites from Shake Shack donat microwave well. The chicken was still very tough; the residual taste in my mouth still very strong.","• F. While this increase in tenderness used to be attributed to a weakening of connective tissue, most now believe it's caused by the change from a viscoelastic to an elastic material: raw meat is tougher because of the viscous flow in the fluid-filled channels between the fibers and fiber bundles; heating up to 65 • C/150 • F increases tenderness because the sarcoplasmic proteins aggregate and gel and makes it easier to fracture the meat with your teeth; over 65",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_261,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""",then for all N sufficiently large there exists a catalysts with spectrum r = r N of dimension N such that,"It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.",Below by p T O → q we mean that one can go from p to q by thermal operations. then for all N sufficiently large there exists a catalysts with spectrum r = r N of dimension N such that (G31) holds true.,[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rstb.2008.0288,Computer_Science_easy_262,A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight.,The hippocampus in humans is therefore necessary for facilitating navigation even when the navigator is an expert of very longstanding.,"A map of its streets looks more like a tangle of yarn that a preschooler glued to construction paper than a metropolis designed with architectural foresight. These navigational demands stimulate brain development, concludes a study five years in the making. With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth.","However, in his navigation, TT was very reliant on main artery or 'A' roads, and became lost when navigation depended instead on non-A roads (figure 4). The hippocampus in humans is therefore necessary for facilitating navigation even when the navigator is an expert of very longstanding. Thus expertise, while taking many years to Review.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1088/1741-2560/13/2/026017,Computer_Science_easy_263,"""This precision is what allowed us to separate the control of individual fingers.""","As expected, the MFCC features proved more effective than any of the neural features.","""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study. ""This precision is what allowed us to separate the control of individual fingers."" Initially, the mind-controlled limb had an accuracy of 76 percent.","Future research efforts could explore alternative modeling and preprocessing techniques to obtain more accurate and less variable results using single-trial data from a single subject. As expected, the MFCC features proved more effective than any of the neural features. However, we were able to observe similarities between the confusion matrices generated using neural and acoustic data (as shown in figures 7 and S1).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1007/978-3-642-55220-5_1,Computer_Science_easy_265,"Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc.","First, λ is the constant in F q 2 which makes the leading terms of the two sides match.","It discredits several cryptographic systems that until now were assumed to provide sufficient security safeguards. Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc. The algorithm they devised stands out from the best algorithms known to date for this problem.","This sequence of formulae calls for a short comment because of an abuse of notation in the last expression. First, λ is the constant in F q 2 which makes the leading terms of the two sides match. The latter may occur since when a/c is in F q , the expression −cα + aβ vanishes for a point (α : β) ∈ P 1 (F q ) so that one of the factors of the product contains no term in P (X).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1411728112,Computer_Science_easy_267,"In this case, we expect to see roughly equal numbers of heads as tails.","Conversely, let us assume that for given states ρ S and ρ S there exists a quantum channel Λ, and a system C with the hamiltonian H C , and state ρ C such that","They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times.","Thus the required transition can be made by catalytic thermal operations. Conversely, let us assume that for given states ρ S and ρ S there exists a quantum channel Λ, and a system C with the hamiltonian H C , and state ρ C such that where ||ρ out S − ρ S || ≤ .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2552/aabc9b,Computer_Science_easy_269,"Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation.","This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device.","This adaptation of the stimulation is the advance we are trying to make with brain stimulation."" Neither patient, males in their 60s diagnosed with Parkinson's seven and eight years earlier, reported feeling changes in stimulation. Researchers saw energy savings of 39 percent and 45 percent in the devices when using the adaptive algorithms.","This strategy requires further testing in a chronic ambulatory setting, and may be useful in PD patients who are motor fluctuators and experience severe dyskinesia alternating with marked bradykinesia . This work illustrates a systematic approach to algorithm development in a neural interface, beginning with the use of sensing for biomarker discovery, then in-clinic testing using an external computer for flexibility in algorithm development, and finally use of control algorithm that is totally embedded within the device. Lower panels show a zoomed in view to demonstrate that classifier state transitions correspond appropriately to fluctuations in gamma band power.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1073/pnas.1411728112,Computer_Science_easy_270,"It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself.","In [11] it was for the first time shown that using catalysis, one can perform transitions otherwise impossible.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","We say that x can be trumped into y if there exists some z such that In [11] it was for the first time shown that using catalysis, one can perform transitions otherwise impossible. Now, if one takes the catalyst r = ( ), then q ⊗ r p ⊗ r, so that q can be trumped into p.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_271,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","Since we have conditions for state transformations using ancillary systems, we are in a position to prove the optimality of the procedure used in [5] .","It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","In I, we discuss in more detail how our paradigm incorporates changing Hamiltonians. Since we have conditions for state transformations using ancillary systems, we are in a position to prove the optimality of the procedure used in [5] . Consider probability distributions p = {p 1 , p 2 , ..., p n } and q = {q 1 , q 2 , ..., q n }.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_272,"Emotions like anxiety, fear, and anger exacerbate political bias, so use soft wording and a calm tone, and try to make them feel at ease.",Drivers need to know the speed expectations so they can drive and react accordingly.,"Avoid using emotionally-charged words and approach them in a way that does not feel threatening. Emotions like anxiety, fear, and anger exacerbate political bias, so use soft wording and a calm tone, and try to make them feel at ease. When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant.",You aren't expecting this low speed when everyone is going at similar speeds to yours. Drivers need to know the speed expectations so they can drive and react accordingly. If everyone goes at whatever speed they want it will only cause many many accidents.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1007/978-3-642-55220-5_1,Computer_Science_easy_273,"Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option.","On the experimental side, it is reasonably easy to sample arbitrary subsets of the rows of H and check for their rank.","The computation of discrete logarithms associated with problems that are deliberately made difficult for cryptographic applications is thus made considerably easier. Since solving this variant of the discrete logarithm is now within the capacity of current computers, relying on its difficulty for cryptographic applications is therefore no longer an option. This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm.","We are, at the moment, unable to provide a proof of a more useful statement. On the experimental side, it is reasonably easy to sample arbitrary subsets of the rows of H and check for their rank. For all values of q considered, we have observed the following facts.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2019.0646,Computer_Science_easy_274,"First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure.","This suggests that disruptive coloration may have to work in tandem with at least some degree of background matching coloration, perhaps indicating it may not be a particularly effective imperfect strategy on its own.","Through these experiments, researchers showed that this choice met four criteria that indicate habituation. First, the female guppies' responsiveness to a stimulus -- male guppies with a familiar pattern -- decreased with added exposure. Second, the females' interest in males with novel patterns was not affected by exposure to the familiar pattern, showing something called stimulus specificity.","In support of this hypothesis, there is some evidence that disruptive markings may be effective even when targets do not match their background colour or luminance . This suggests that disruptive coloration may have to work in tandem with at least some degree of background matching coloration, perhaps indicating it may not be a particularly effective imperfect strategy on its own. To resolve this debate, it may be productive to approach the question differently by testing how adding different types of disruptive markings alters the performance of a target displaying an optimal compromise pattern.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1007/978-3-642-55220-5_1,Computer_Science_easy_276,"Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research.","Without loss of generality, we may assume Q = ∞ = (1 : 0).","This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research. For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","Q ∈ P 1 (F q 2 ) is the number of image sets m −1 · P 1 (F q ) which contain both (0 : 1) and Q, which we prove is equal to q + 1 as follows. Without loss of generality, we may assume Q = ∞ = (1 : 0). We need to count the relevant homographies m We may normalize to d = 1, and notice that multiplication of a by a scalar in F * q is absorbed in PGL 2 (F q )-equivalence.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_277,"If it ainat broke, donat fix it a and McDonaldas McNuggets are far from broken.","• C/126.1 • F, when the common food pathogen C. perfringens stops multiplying, it takes a very long time to reduce the food pathogens we're worried aboutnamely the Salmonella species, L. monocytogenes, and the pathogenic strains of Escherichia coli -to a safe level; in a 54.4","And no matter how long they may or may not remain in a refrigerator before being reheated, they taste as if youave just ordered them. McDonaldas remains the champion of the nugget world because itas managed to master the right amount of crunch and seasoning, both of which were absent from Shake Shackas iteration. If it ainat broke, donat fix it a and McDonaldas McNuggets are far from broken.","At 52.3 • C/126.1 • F, when the common food pathogen C. perfringens stops multiplying, it takes a very long time to reduce the food pathogens we're worried aboutnamely the Salmonella species, L. monocytogenes, and the pathogenic strains of Escherichia coli -to a safe level; in a 54.4 • C/130",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1007/s10055-018-0346-3,Computer_Science_easy_278,"""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says.","After one week, the overall scores and confidence levels dropped consistently across the board, with the viewing condition having no effect on the relative reduction in performance.","This was reflected in the research results: 40 percent of the participants scored at least 10 percent higher in recall ability using VR over the desktop display. ""This leads to the possibility that a spatial virtual memory palace -- experienced in an immersive virtual environment -- could enhance learning and recall by leveraging a person's overall sense of body position, movement and acceleration,"" Plaisant says. The UMD team believes this study will lay the groundwork for other scientific inquiry on the value of VR and AR for education.","The study found that immediately after the exposure the participants had the most accurate recall in the real-world scene and were slightly less accurate and confident in the HMD and least accurate and confident on the desktop. After one week, the overall scores and confidence levels dropped consistently across the board, with the viewing condition having no effect on the relative reduction in performance. In this inspirational study, the participants only experienced one display.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34299069033&p=1pl&v=1&x=XwPIOwPBqw9PE_RGIV509w
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_279,Itas hard to eat more than a few at a time because of the overwhelming seasoning.,"Even for healthy people, it's important that raw and unpasteurized foods are consumed before food pathogens have had time to multiply to dangerous levels; most foods shouldn't be above 21","Fresh, free of antibiotics and all the other buzzwords give it the advantage here. Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part.","This raw or undercooked food should only be served to informed healthy adults who understand and accept the risks and never to immuno-compromised people. Even for healthy people, it's important that raw and unpasteurized foods are consumed before food pathogens have had time to multiply to dangerous levels; most foods shouldn't be above 21 • C/70",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_280,"Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment.","ρ( , )","""He suggested that the coincidence in the sensory input may play a crucial role."" Although the external agent configuration x can be the same, its sensory experience varies greatly depending on the structure of the environment. The ideas introduced by Poincare can be better explained with a simple example.","For example, such a representation can be used to reduce the dimensionality when sampling a new visual environment: the agent with an explicit internal representation ""knows"" that it needs to sample the three-dimensional space of the internal representation and not the full fourdimensional space of motor commands. ρ( , ) i j Figure 4 : The Hausdorff distance between two sets M i and M j corresponds to the greatest of all the distances from a point in one set to the closest point in the other set.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1411728112,Computer_Science_easy_281,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""",5).,"It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","Note however, that we can rule out negative α in a different way, if instead of insisting on preparing exact output state, we allow for preparing an ε-approximation, with arbitrary accuracy (as discussed in Prop. 5). Therefore, in case (iii) considered above we can add to both sides an ancilla in a pure state of the same dimension (which is actually needed only when p and q both have no zeros).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_283,"The proof-of-concept feat, described online this week in the Journal of Neural Engineering, represents a potential advance in technologies to restore refined hand function to those who have lost arms to injury or disease, the researchers say.",2.1.4.,"The proof-of-concept feat, described online this week in the Journal of Neural Engineering, represents a potential advance in technologies to restore refined hand function to those who have lost arms to injury or disease, the researchers say. ""This technology goes beyond available prostheses, in which the artificial digits, or fingers, moved as a single unit to make a grabbing motion, like one used to grip a tennis ball. ""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study.","The TIMIT and Gump sets comprised of 499 and 382 unique stimuli, respectively. 2.1.4. These rejected channels contained time segments that differed greatly in magnitude from the channels that were deemed normal, which is often caused by non-physiological factors (poor electrode contact with the cortical surface, electromagnetic interference from hospital equipment, defective electrodes or wires, etc).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1073/pnas.1411728112,Computer_Science_easy_284,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","However, in models where the Hamiltonian is trivial, i.e.","Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","This is because transitions between pure states are not effected by catalysis. However, in models where the Hamiltonian is trivial, i.e. H = 0, one needs an alternative way to define work.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_286,"Initially, the mind-controlled limb had an accuracy of 76 percent.","Using relatively simple feature extraction techniques and model components, our NSR system was able to perform, to a limited extent, continuous speech decoding using neural signals.","""This precision is what allowed us to separate the control of individual fingers."" Initially, the mind-controlled limb had an accuracy of 76 percent. Once the researchers coupled the ring and pinkie fingers together, the accuracy increased to 88 percent.","Overall, the differences between evaluations for each neural feature were negligible compared to the differences observed for acoustic features. Using relatively simple feature extraction techniques and model components, our NSR system was able to perform, to a limited extent, continuous speech decoding using neural signals. The novel results presented in this work quantitatively indicate that spatiotemporal modeling and ASR techniques, specifically language modeling and Viterbi decoding, can be used to improve phoneme recognition when using neural response features and continuous speech stimuli.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1126/science.aaf2654,Computer_Science_easy_287,"That day, the Boston Public Schools decided not to implement the changes.","A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far.","In the op-ed, we piled on in criticizing the changes but argued that people shouldn't criticize the algorithm, but rather the city's political process that prescribed the way in which the various concerns and interests would be optimized. That day, the Boston Public Schools decided not to implement the changes. A month later, a more nuanced picture emerged, one that I think offers insights into how technology can and should provide a platform for interacting with policy--and how policy can reflect a diverse set of inputs generated by the people it affects.","To align moral algorithms with human values, we must start a collective discussion about the ethics of AVs, that is, the moral algorithms that we are willing to accept as citizens and to be subjected to as car owners. A possible concern with MTurk studies is that some participants may already be familiar with testing materials, when these materials are used by many research groups; but this concern does not apply to our testing materials, which have never been used in a published MTurk study so far. Regression analyses (see Supplementary online materials) showed that enthusiasm for self-driving cars was consistently greater for younger, male participants.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37598037254&p=1pl&v=1&x=8McLEcTaeJE34juXGV2oZg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_288,Chickan Bites from Shake Shack donat microwave well.,• C/95-105 • F and the shrinkage increases almost linearly up to 80,"McDonaldas, because theyare more delicious. Chickan Bites from Shake Shack donat microwave well. The chicken was still very tough; the residual taste in my mouth still very strong.",The muscle fibers start to shrink at 35-40 • C/95-105 • F and the shrinkage increases almost linearly up to 80 • C/175,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_289,Itas hard to eat more than a few at a time because of the overwhelming seasoning.,At lower temperatures (50 found that tough cuts of beef (from animals 0-4 years old) were the most tender when cooked to between 55,"Fresh, free of antibiotics and all the other buzzwords give it the advantage here. Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part.",At 80 found that these effects occur within about 12-24 hours with tenderness increasing only slightly when cooked for 50 to 100 hours. At lower temperatures (50 found that tough cuts of beef (from animals 0-4 years old) were the most tender when cooked to between 55 • C/131 • F and 60,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1088/1741-2560/13/2/026017,Computer_Science_easy_291,"""This precision is what allowed us to separate the control of individual fingers.""",The LM used in the NSR system provides estimates for the a priori probabilities of phonemic sequences.,"""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study. ""This precision is what allowed us to separate the control of individual fingers."" Initially, the mind-controlled limb had an accuracy of 76 percent.","The r 2 values for each relevant electrode for each subject are depicted in figure 2. The LM used in the NSR system provides estimates for the a priori probabilities of phonemic sequences. Approximately 4.3 million sentences were included, resulting in a phoneme corpus with about 76.9 million non-silence phonemes (a total of about 81.2 million phoneme tokens when /sp/ is included).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_292,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was.",• C/140,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.",For the fast changes: The muscle fibers begin to shrink at 35-40 • C/140 • C/160 • F and above is well done.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1007/978-3-642-55220-5_1,Computer_Science_easy_293,The algorithm they devised stands out from the best algorithms known to date for this problem.,By construction this field contains F Q (because p|q and n|2k) and it is in the range of applicability of Theorem 3.,"Although this work is still theoretical, it is likely to have repercussions especially on the cryptographic applications of smart cards, RFID chips (2), etc. The algorithm they devised stands out from the best algorithms known to date for this problem. Not only is it significantly easier to explain, but its complexity is also considerably improved.","While we have seen that Corollary 4 can be used to treat some cases, its applicability might be hindered by the absence of an appropriately sized subfield: p might be as small as 2, and n might not factor adequately. By construction this field contains F Q (because p|q and n|2k) and it is in the range of applicability of Theorem 3. Therefore, one can solve a discrete logarithm problem in F Q in time max(q, k) O(log k) .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_295,"In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.",• F?,"Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game. McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions.",• C/140 • F? Because it takes days for food pathogens to grow to a dangerous level at 4.4,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_296,"""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see.""",The final structure captured by the agent will thus be closer to what we intuitively expect from a notion of space.,"These low-probability events may be used by the brain to construct general perceptual notions."" ""The most important thing is that even though this abstract notion is learned based on the visual input, it ends up being independent from it, and thus works for all environments; the same way our notion of space does not depend on the particular scene we see."" ""The tricky part of our study was that the robot had to complete this task by looking into the distorted images only, just like humans learn to compensate for the distortion introduced by eye glasses,"" Terekhov said.","By searching only for displacements or, in sensorimotor terms, transformations that both the agent and objects in the environment can perform, it should be possible to avoid capturing such non-spatial degrees of freedom. The final structure captured by the agent will thus be closer to what we intuitively expect from a notion of space. The authors would like to thank anonymous reviewers for their useful comments contributing towards better positioning and clarity of the manuscript.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_297,But at least people think Shake Shack is cool and trendy.,• C/70,"Barack Obama and Joe Biden at Shake Shack Alex Wong/Getty Images

No, you canat bring Shake Shackas nuggets to an important meeting in a small room. But at least people think Shake Shack is cool and trendy. Bringing McNuggets to a work meeting isnat a great idea, either.","Even for healthy people, it's important that raw and unpasteurized foods are consumed before food pathogens have had time to multiply to dangerous levels; most foods shouldn't be above 21 • C/70 • C/80",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_299,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","Demanding that the catalyst be returned uncorrelated from the system is natural, since one is likely to want to re-use the catalyst over many cycles, and having correlations between the catalyst and the system could result in inefficiencies later on.","Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","In other words, (ρ, H) can be catalytically transformed into (ρ , H ) if there exists catalyst (ρ C , H C ) such that (ρ⊗ρ C , H +H C ) can be transformed into (ρ ⊗ ρ C , H + H C ). Demanding that the catalyst be returned uncorrelated from the system is natural, since one is likely to want to re-use the catalyst over many cycles, and having correlations between the catalyst and the system could result in inefficiencies later on. One could also imagine that the purification of the catalyst is held somewhere, and require that the catalyst and its purification remain close to its original state.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_300,"While this task can certainly be difficult, the good news is that it is by no means impossible.","Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts.","If you consider yourself a good Samaritan, such an effort should be considered a moral responsibility and an ethical imperative. While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","There are many possible extensions to our approach for representing arguments. Furthermore, although this novel dataset opens up potential opportunities for future work, other environments, where people are not as open-minded, can exhibit different kinds of persuasive interactions; it remains an interesting problem how our findings generalize to different contexts. Finally, beyond mechanisms behind persuasion, it is a vital research problem to understand how community norms encourage such a well-behaved platform so that useful rules, moderation practices, or even automated tools can be deployed in future community building.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_301,"However, this is not true when tossing the coin just a few times.","Denoting the inverse of E as E * , hence","In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails.","If q also contains irrational values, we can similarly define a second correction map that maps q intoq while not perturbing p too much. Denoting the inverse of E as E * , hence and",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1038/s41598-018-30656-7,Computer_Science_easy_302,This suggests that compound tool making is a cognitively difficult step a and makes it all the more impressive that Mango and his friends figured it out.,The fact that the less preferred option experiences more severe cross-censoring (only the extreme of its left tail sees action) leads to one additional prediction in the SCM: the predicted shortening of latency for binary respect to single-option choices is more pronounced for the worse (less preferred) option than for the better (preferred) option.,"(Mango was the only bird that made tools out of three or four parts.) This suggests that compound tool making is a cognitively difficult step a and makes it all the more impressive that Mango and his friends figured it out. aIt is possible that this can only be done by some form of mental simulation of the outcome.a

Experimental setup in the construction test.","This interaction cross-censors the right tails of both latency distributions, and thus when an option is encountered and chosen in the presence of an alternative, observed mean latencies are shorter than those for the option when presented alone 28 . The fact that the less preferred option experiences more severe cross-censoring (only the extreme of its left tail sees action) leads to one additional prediction in the SCM: the predicted shortening of latency for binary respect to single-option choices is more pronounced for the worse (less preferred) option than for the better (preferred) option. As noted above, the ToW model predicts a shift in the opposite direction (i.e.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1073/pnas.1411728112,Computer_Science_easy_305,"""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).",This is equivalent to requiring that,"In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","It is reasonable that for any definition of work system and work extraction, we require that one can reversibly go from state W i to W f and visa versa. This is equivalent to requiring that This is because if F α (W f ρ β W ) − F α (W i ρ β W ) were different for two values of α, then it would require a different amount of pure energy to go from the initial state to the final state, than from the final state to the initial.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_306,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","However, this is only so when we do not allow ancillary systems that are then returned in the same state.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","As we mentioned, in this toy thermodynamics, the law that governs state-to-state transitions is majorization. However, this is only so when we do not allow ancillary systems that are then returned in the same state. It is interesting to analyse how the laws change if we allow catalytic transitions between states.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_307,"Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","If we slightly perturb y so that we remove zeros, then we do not need to truncate anymore.","""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.","Second, the condition of having zeros in both vectors is very unstable. If we slightly perturb y so that we remove zeros, then we do not need to truncate anymore. Note that the problem here is only with negative α, as for positive α the functions D α (p||η) do not depend on additional zeros, while the functions with negative α are infinite, when at least one component vanishes.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_309,"In this case, we expect to see roughly equal numbers of heads as tails.","Next we show that it is sufficient to consider catalysts diagonal w.r.t its Hamiltonian, when the initial state is already block diagonal in the energy eigenbasis.","They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times.","In this case, the Hamiltonian of the system and reservoir are arbitrary. Next we show that it is sufficient to consider catalysts diagonal w.r.t its Hamiltonian, when the initial state is already block diagonal in the energy eigenbasis. Given probability distributions p, q, p , q , we say that (p, q) d-majorizes (p , q ) if and only if for any convex function g,",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.robot.2015.01.003,Computer_Science_easy_310,could be instilled in biological or artificial systems.,"They provide the tool required to work with such notion as the length of a path, and can underlie navigation abilities.","a) 1% of the 2500 exploratory arm configurations mi . could be instilled in biological or artificial systems. ""These concepts are instead developed over time, as useful tools that help them to make sense of the vast sensorimotor data they are constantly exposed to.","Although rather primitive, topological space nevertheless includes some fundamental aspects of space in general, such as dimensionality, and its notion can be useful in such tasks as the mapping of large spaces . They provide the tool required to work with such notion as the length of a path, and can underlie navigation abilities. In particular, knowledge of a metric space enables odometry and SLAM .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1419704112,Computer_Science_easy_311,"This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""",One possible explanation for this association is that change is highest when populations are divided.,"Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language."" It should also be clarified that the only occasions on which a Redditor might rage quite a cat cafe are when no bacon is available; or if it's one of those Redditors who show up in the ""unpopular opinions"" AskReddit threads hating on cats.","If the finding that rates of word gain are greatest in large populations is a general feature of language change, then it has implications for understanding the connection between rate of language change and the diversification of language families. One possible explanation for this association is that change is highest when populations are divided. However, our results suggest that small subdivided populations may be more likely to undergo word loss than accelerated gain of new words.",[1],Computer_Science,train,1.0,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1145/2872427.2883081,Computer_Science_easy_312,"While this task can certainly be difficult, the good news is that it is by no means impossible.","Disclaimer: Features that lose predictive power in the root truncated setting (or ""reverse direction"" 11 ) are not necessarily false positives (or non-significant), as truncation can remove significant fractions of the text and lead to different distributions in the resultant dataset.","If you consider yourself a good Samaritan, such an effort should be considered a moral responsibility and an ethical imperative. While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","This forcefully removes all length effects. Disclaimer: Features that lose predictive power in the root truncated setting (or ""reverse direction"" 11 ) are not necessarily false positives (or non-significant), as truncation can remove significant fractions of the text and lead to different distributions in the resultant dataset. Our point, though, is: if features retain predictive power even in the root truncated settings, they must be indicative beyond length.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_313,"""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","Clearly, this unitary acted upon the initial joint state ρ A k ⊗ |m m| B extracts ω ≥ 0 amount of work into the battery system with probability p i , and − ω with probability p j , while the expectation value of work extracted is given by the difference in expected energy in the battery system,","The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average.","Then by the definition of passivity, there exists some i, j where E i > E j , p i > p j holds. Clearly, this unitary acted upon the initial joint state ρ A k ⊗ |m m| B extracts ω ≥ 0 amount of work into the battery system with probability p i , and − ω with probability p j , while the expectation value of work extracted is given by the difference in expected energy in the battery system, Now, similarly, consider the initial state ρ A1 ⊗ · · · ⊗ ρ Am ⊗ |m m| B , and the unitary transformation U m · · · U 1 .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_314,The results of the study give an improved understanding of how heat and energy is transformed on very small scales.,We then show that this provides the basis of catalytic transformations in the simple setting where the Hamiltonian is trivial.,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly."" The results of the study give an improved understanding of how heat and energy is transformed on very small scales.","One hopes that such information theoretic laws can be used to discover a broad range of thermodynamical phenomena at the quantum level. We then show that this provides the basis of catalytic transformations in the simple setting where the Hamiltonian is trivial. Our main technical result is Theorem17, which generalises trumping relations from the bistocastic case, to the case of arbitrary channels which take a subset of states to some other subset of states.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1419704112,Computer_Science_easy_316,"Here's the full list of newly inducted words, which can now be found on OxfordDictionaries.com:","Our analysis provides, to our knowledge, the first statistically robust evidence of an influence of population size on rate of language change.","This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language."" It should also be clarified that the only occasions on which a Redditor might rage quite a cat cafe are when no bacon is available; or if it's one of those Redditors who show up in the ""unpopular opinions"" AskReddit threads hating on cats. Here's the full list of newly inducted words, which can now be found on OxfordDictionaries.com:","Here, we use data from closely related pairs of languages to show that a key prediction of evolutionary theory is met: rates of gain of new words are higher in larger populations whereas rates of word loss are greater in small populations. Our analysis provides, to our knowledge, the first statistically robust evidence of an influence of population size on rate of language change. These results demonstrate the potential for demographic factors to influence language evolution.",[1],Computer_Science,train,1.0,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1145/2872427.2883081,Computer_Science_easy_317,"While this task can certainly be difficult, the good news is that it is by no means impossible.","(*: p < 0.05, **: p < 0.01, ***:","If you consider yourself a good Samaritan, such an effort should be considered a moral responsibility and an ethical imperative. While this task can certainly be difficult, the good news is that it is by no means impossible. While it is true that some may have biases too deeply-engrained for them to change, that certainly isn't the case for all of them.","BOW, POS, style and all outperform random guessing using bootstrapped tests. (*: p < 0.05, **: p < 0.01, ***: The full feature set (all) also significantly outperform the #words baseline.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_319,"It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself.","In general, we find that more work can be extracted in a cyclic process, and in Section F 5 of the Supplementary Information, we derive the optimal amount of extractable work in such a case, providing an operational interpretation for the difference of Rényi entropies, and an interpretation for when this quantity is negative.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","Here, we find that even more work can be extracted during a memory reset. In general, we find that more work can be extracted in a cyclic process, and in Section F 5 of the Supplementary Information, we derive the optimal amount of extractable work in such a case, providing an operational interpretation for the difference of Rényi entropies, and an interpretation for when this quantity is negative. For states that are not diagonal in the energy basis, we provide generalization of the above limitations in terms of quantum alpha-free energies in Sec.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_320,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was.","Vacuum packaging doesn't reduce the microorganisms, so you must either return it to the refrigerator or freezer or (in most cases) begin cooking immediately in a temperature controlled water bath.","aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.","Because of limited space, only some of the biological hazards for sous vide cooking and their controls are discussed below: Vacuum packaging doesn't reduce the microorganisms, so you must either return it to the refrigerator or freezer or (in most cases) begin cooking immediately in a temperature controlled water bath. 3.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1088/1741-2552/aabc9b,Computer_Science_easy_321,"The findings, Swann says, lay the groundwork for more complex algorithms to achieve that balance in improved versions of the device.","Rather, multiple transitions were triggered by relatively small fluctuations in the neural signal, fluctuations which were likely too small to correlate with overt behavioral changes.","Researchers saw energy savings of 39 percent and 45 percent in the devices when using the adaptive algorithms. The findings, Swann says, lay the groundwork for more complex algorithms to achieve that balance in improved versions of the device. ""Ultimately, this could be customized for each person to keep them in their ideal brain state,"" Swann says.","Using this approach transitions in the classifier state occurred much more frequently than would be expected if transitions were only triggered by changes in the clinical state of the patient. Rather, multiple transitions were triggered by relatively small fluctuations in the neural signal, fluctuations which were likely too small to correlate with overt behavioral changes. Further, the amplitude of the neural signal used for control (gamma band power) also fluctuated rather than stabilized, possibly in part due to frequent voltage transitions.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1145/2872427.2883081,Computer_Science_easy_322,Support these facts with data from scientific or politically-neutral sources.,in all,"Once that common ground has been established, it becomes much easier to explain that these individuals exist as a very small minority, and that most immigrants come to this country for the same American dream of freedom and opportunity that they hold. Support these facts with data from scientific or politically-neutral sources. ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away.","T in the root reply column indicates that the feature is also significant in the root truncated condition, while T R means that it is significant in root truncated but the direction is reversed. in all The context established by the OP's statement of her view can provide valuable information in judging the relative quality of a challenger's arguments.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_323,"In this case, we expect to see roughly equal numbers of heads as tails.","We now make use of the fact that the function f (x) = x α is convex for α > 1, over all x > 0 (This be checked since the second derivative of f (x) is positive over the range of x > 0).","They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times.","For any two sets of distributions (A 1 , B 1 ) and (A 2 , B 2 ), and a parameter 0 < δ < 1, the Rényi divergence in this range of α satisfies We now make use of the fact that the function f (x) = x α is convex for α > 1, over all x > 0 (This be checked since the second derivative of f (x) is positive over the range of x > 0). and since each q 1−α i > 0, the linear combination",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_324,"Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason.","As shown in §4.2, the number of words is very predictive, providing a strong baseline to compare against.","ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason. Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","The results are, in fact, in line with what we describe in the training-data analysis here. As shown in §4.2, the number of words is very predictive, providing a strong baseline to compare against. Note that style and interplay are dense and very low-dimensional compared to BOW.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_325,"In a sense, the traditional second law only holds on average.",α−1 log F (p).,"""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","p. For any p = q, note that F (p) > 1 comes from the positivity of the Rényi divergences, since α−1 log F (p). Also, note that for a fixed q, F (q) = i q i = 1.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_326,"From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation.","A late entry might give the challenger time to read attempts by other challengers and better formulate their arguments, while an early entry might give her the first-mover advantage.","It doesn't matter whether you're a Republican, Democrat, Libertarian, or something else--if you are a reasonable person then you must be wondering what the hell hardcore Trump supporters are thinking right now. From wearing shirts that say, ""I'd rather be a Russian than Democrat,"" to conspiracy theories that Hillary Clinton was running a pedophilia ring out of a pizza joint, it is obvious that Donald Trump and abominable allies have perfected the skill of brain washing those vulnerable to such manipulation. But completely giving up on the task of converting fellow Americans--even staunch Trump supporters and outlandish conspiracy theorists--into crusaders for logic and reason should not be an option.","For posts where the OP gave at least one delta, the OP gave 1.5 deltas on average. A late entry might give the challenger time to read attempts by other challengers and better formulate their arguments, while an early entry might give her the first-mover advantage. Even for original posts that eventually Note that although reply display order is affected by upvotes, entry time is an important factor when the OP follows the post closely.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34828472692&p=1pl&v=1&x=4ruYvZS5w6QcN2Gi21xOEg
10.1126/science.aaf2654,Computer_Science_easy_327,One of the moral dilemmas they were faced with involved civilians who were hiding from soldiers who were out to kill.,"This is a huge gap from a statistical perspective, but it must be understood as reflecting the state of public sentiment at the very beginning of a new public issue, and thus not guaranteed to persist.","""The findings give us a glimpse into what is the nature of morality,"" study author Dr. Marco Iacoboni, a psychiatry professor at UCLA, said in a statement. One of the moral dilemmas they were faced with involved civilians who were hiding from soldiers who were out to kill. Their hypothesis was accurate, but as they also predicted, they didn't find an association between brain activity and harming a person for the benefit of the public.","The median expressed likelihood of purchasing an unregulated AV was 59, compared to 21 for purchasing a regulated AV. This is a huge gap from a statistical perspective, but it must be understood as reflecting the state of public sentiment at the very beginning of a new public issue, and thus not guaranteed to persist. Three groups may be able to decide how AVs handle ethical dilemmas: the consumers who buy the AVs; the manufacturers that must program the AVs in the first place; and the government which may regulate the kind of programming that manufacturers can offer and consumers can choose from.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32987984951&p=1pl&v=1&x=1g42vs7c-hPYDcKYkzy-jQ
10.1088/1741-2560/13/2/026017,Computer_Science_easy_328,"The researchers note there was no pre-training required for the subject to gain this level of control, and the entire experiment took less than two hours.","HGWs consistently provided improvements when compared to HGSs, but the use of a phonemic LM and Viterbi decoding typically provided improvements only for the PER and confusion accuracy metrics and not for the posteriogram accuracy metric.","""It makes sense that coupling these two fingers improved the accuracy."" The researchers note there was no pre-training required for the subject to gain this level of control, and the entire experiment took less than two hours. Crone cautions that application of this technology to those actually missing limbs is still some years off and will be costly, requiring extensive mapping and computer programming.","As described in section 3.2, the use of HGWs over HGSs and the use of language modeling and decoding tended to improve performance. HGWs consistently provided improvements when compared to HGSs, but the use of a phonemic LM and Viterbi decoding typically provided improvements only for the PER and confusion accuracy metrics and not for the posteriogram accuracy metric. The similarity in the posteriogram accuracy values for estimation and decoding results suggest that the basic phoneme priors used in the estimation results (as described in section 2.2.1) were as effective at frame-by-frame classification as the phonemic LM used in the decoding results.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1073/pnas.1411728112,Computer_Science_easy_330,"In other words, just like larger systems, small systems also tend to become more disordered.","The ordinary free energy continues to govern whether a thermodynamical transition is possible, while the Rényi-divergences do not.","Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered. ""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk).","In this case, we recover the second laws as stated above. The ordinary free energy continues to govern whether a thermodynamical transition is possible, while the Rényi-divergences do not. We thus see that the ordinary second law can arise in the macroscopic limit, or if we allow processes which deviate from being cyclic in a manner which is constant per number of particles in the working body.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_331,"The proof-of-concept feat, described online this week in the Journal of Neural Engineering, represents a potential advance in technologies to restore refined hand function to those who have lost arms to injury or disease, the researchers say.",Future research efforts could explore alternative modeling and preprocessing techniques to obtain more accurate and less variable results using single-trial data from a single subject.,"The proof-of-concept feat, described online this week in the Journal of Neural Engineering, represents a potential advance in technologies to restore refined hand function to those who have lost arms to injury or disease, the researchers say. ""This technology goes beyond available prostheses, in which the artificial digits, or fingers, moved as a single unit to make a grabbing motion, like one used to grip a tennis ball. ""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study.","The results using concatenated feature vectors illustrate the upper limits on system performance and the amount of information available in recorded neural signals given the current physical and methodological limitations of our system. Future research efforts could explore alternative modeling and preprocessing techniques to obtain more accurate and less variable results using single-trial data from a single subject. As expected, the MFCC features proved more effective than any of the neural features.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_332,"Still, though, I had some lingering questions about their safety.",Vacuum-sealing's main benefit is that it allows heat to be efficiently transferred from the water bath or steam oven to the meat.,"They didn't melt, burn or make me sick. Still, though, I had some lingering questions about their safety. Plus, if you want to get all of the air out of the bag without a vacuum sealer, you can use the water displacement method to get the best results.","This typically doesn't leave any obvious marks on the meat and reduce moisture lose by cutting internal fibers that would have contracted with heating. Vacuum-sealing's main benefit is that it allows heat to be efficiently transferred from the water bath or steam oven to the meat. For cook-chill or cook-freeze sous vide cooking, vacuum packaging eliminates the risk of recontamination during storage and inhibits off-flavors from oxidation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1145/2872427.2883081,Computer_Science_easy_334,"Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason.","Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic.","ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason. Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","In response to the same original post, there are many possible ways to change someone's view. Hence, for each rooted path-unit that wins a ∆, we find the rooted path-unit in the same discussion tree that did not win a ∆ but was the most ""similar"" in topic. This leads to a balanced binary prediction task: which of the two lexically similar rooted path-units is the successful one?",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_335,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.","Interpreted strictly, the Clausius statement of the second law, applies to situations which never occur in nature.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","In the case of microscopic, quantum or highly correlated systems, a criteria for state transitions of a total system was proven in [5] and named arXiv:1305.5278v4 [quant-ph] Interpreted strictly, the Clausius statement of the second law, applies to situations which never occur in nature. The same holds true for other versions of the second law, such as the Kelvin-Planck statement, where one also talks about cyclic processes, in which all other objects beside the system of interest are returned back to their original state.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/978-3-642-55220-5_1,Computer_Science_easy_336,"For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","Much the same can be said in the case where n is composite and factors nicely, so that F Q admits a large enough subfield F q with q = p m .","This work is still at a theoretical stage and the algorithm still needs to be refined before it is possible to provide a practical demonstration of the weakness of this variant of the discrete logarithm. Nonetheless, these results reveal a flaw in cryptographic security and open the way to additional research. For instance, the algorithm could be adapted in order to test the robustness of other cryptographic applications.","In this case F Q , or possibly F Q 2 if n is odd, can be represented in such a way that Corollary 4 applies. Much the same can be said in the case where n is composite and factors nicely, so that F Q admits a large enough subfield F q with q = p m . This can be used to solve certain discrete logarithms in, say, F 2 n for adequately chosen n (much similar to records tackled by ).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140515163739.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1411728112,Computer_Science_easy_337,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","This means that we do not simply compare two functions, but which function we will choose depends on some relation between the vectors.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","Namely, if there are zeros in both x and y we have to truncate the zeros and compute the conditions on smaller vectors. This means that we do not simply compare two functions, but which function we will choose depends on some relation between the vectors. Second, the condition of having zeros in both vectors is very unstable.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_339,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.",The trace norm distance between two states ρ and σ can be written as,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","At first glance, one might be tempted to demand that close should mean that ρ in C is close to ρ out C in terms of the fidelity, or essentially equivalently, the trace norm distance. The trace norm distance between two states ρ and σ can be written as It enjoys an appealing operational interpretation as being -close in trace norm distance means that if we were given states ρ and σ with probability 1/2 each, then our probability of correctly distinguishing them by any physically allowed measurement is bounded by 1/2 + /2.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_340,"The winner: McDonaldas Chicken McNuggets

Everything about Shack Shakeas chicken nuggets is great, in theory.",• C/185,"Theyare also a little juvenile in their small boxes, which means your co-workers wonat take you seriously when you have something to say. The winner: McDonaldas Chicken McNuggets

Everything about Shack Shakeas chicken nuggets is great, in theory. Fresh, antibiotic-free chicken breast you can order from an iPad a whatas not to love?",• C/167 • C/185 • F ; FDA (2011) gives a more conservative time of 10 minutes at 90,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.compag.2016.07.028,Computer_Science_easy_341,"The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers.","To the best of our knowledge, our study is the first to use a hyperspectral imaging system to measure leaf water content of whole living maize plants.","The system can rapidly measure and compare the physical traits, or phenotypes, of different crop varieties by transporting plants through several 360-degree imaging chambers. The crop's unwieldy size and complex anatomy have left it mostly ignored by previous automated phenotyping work, the researchers said. We were fairly successful in doing that.""","Based on these previous knowledges, hyperspectral imaging is suggested as a powerful tool in plant phenotyping to complement RGB analysis (to obtain plant chemical traits in addition to morphological traits). To the best of our knowledge, our study is the first to use a hyperspectral imaging system to measure leaf water content of whole living maize plants. Data points were missing on DAS 22 due to an unexpected disruption of the automated imaging routine on that day.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1073/pnas.1411728112,Computer_Science_easy_342,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","What's more, one needs to be more precise about what one means by a cyclic process.","It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","At the macroscopic scale, and for systems with short range correlations, this entire family of second laws become equal to the ordinary second law, but outside of this regime, these other second laws impose additional restrictions on thermodynamical transitions. What's more, one needs to be more precise about what one means by a cyclic process. Here, we show that this is not the case in the microscopic regime, and we therefore needs to talk about ""how cyclic"" a process is when stating the second law.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_343,"""This technology goes beyond available prostheses, in which the artificial digits, or fingers, moved as a single unit to make a grabbing motion, like one used to grip a tennis ball.",Over 50% of the relevant channels for each subject were located in the STG.,"The proof-of-concept feat, described online this week in the Journal of Neural Engineering, represents a potential advance in technologies to restore refined hand function to those who have lost arms to injury or disease, the researchers say. ""This technology goes beyond available prostheses, in which the artificial digits, or fingers, moved as a single unit to make a grabbing motion, like one used to grip a tennis ball. ""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study.","The fewer number of relevant channels for subject C could be a result of electrode coverage over the language non-dominant hemisphere, although existing literature indicates that phonetic processing occurs bilaterally . Over 50% of the relevant channels for each subject were located in the STG. 2.1.5.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1145/2872427.2883081,Computer_Science_easy_345,"Also, it is a good idea to cite reputable sources and provide links to external sites, so that information is recognized as objective, rather than a biased opinion.","In §6, we discuss other observations that may open up future directions, including attempts to capture higher-level linguistic properties (e.g., semantics and argument structure); §7 summarizes additional related work and §8 concludes.","ADVERTISEMENT

When you engage Trump loyalists in debate, try to respond with meaty content that has greater numbers of sentences and paragraphs, since research shows that one-liners and superficial statements do little to persuade people. Also, it is a good idea to cite reputable sources and provide links to external sites, so that information is recognized as objective, rather than a biased opinion. Avoid using emotionally-charged words and approach them in a way that does not feel threatening.","While we believe that the observations we make are useful for understanding persuasion, we do not claim that any of them have causal explanations. In §6, we discuss other observations that may open up future directions, including attempts to capture higher-level linguistic properties (e.g., semantics and argument structure); §7 summarizes additional related work and §8 concludes. CMV is wellsuited to our purposes because of its setup and mechanics, the high quality of its arguments, and the size and activity of its user base.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_346,"It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself.","Note that the problem here is only with negative α, as for positive α the functions D α (p||η) do not depend on additional zeros, while the functions with negative α are infinite, when at least one component vanishes.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","If we slightly perturb y so that we remove zeros, then we do not need to truncate anymore. Note that the problem here is only with negative α, as for positive α the functions D α (p||η) do not depend on additional zeros, while the functions with negative α are infinite, when at least one component vanishes. First let us note, that we can eliminate the first problem by requiring that the output is returned not exactly, but only with arbitrary high accuracy.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_347,"McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions.","Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90","In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game. McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions. Fresh, free of antibiotics and all the other buzzwords give it the advantage here.","). Legumes cooked sous vide don't need to be pre-soaked, because they can absorb the same amount of water in 50 minutes at 90 • C/195",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_348,"In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.",• C/175,"Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game. McNuggets were a beacon of hope and remain that way for me now, in spite of competitors offering new or healthier renditions.",• C/180-185 • C/175 • C/195,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1038/s41598-018-30656-7,Computer_Science_easy_350,"They probably include the speciesa typical propensity to use tools, their ability to judge affordances that make some objects usable as tools, and an ability to innovate perhaps through virtual, cognitive simulations.","In the SCM, in contrast, options 'compete' to be chosen by generating a candidate latency independently sampled from the distribution belonging to each option when alone.","While this latest study doesnat imply that the cognitive powers of a crow rival those of humans or apes, it hints that they too have evolved to perform complex tasks with coordination and ease. Our results are not accountable by direct reinforcement learning but corroborate that these crows possess highly flexible abilities that allow them to solve novel problems rapidly. They probably include the speciesa typical propensity to use tools, their ability to judge affordances that make some objects usable as tools, and an ability to innovate perhaps through virtual, cognitive simulations.","is consistent with the idea of ""choice overload"". In the SCM, in contrast, options 'compete' to be chosen by generating a candidate latency independently sampled from the distribution belonging to each option when alone. The option reaching the threshold first becomes the ""choice"" (see 32 for a discussion of calling the outcome of such process a choice), and the latency elicited by the not-chosen alternative is simply not expressed or observed.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_351,"McDonaldas remains the champion of the nugget world because itas managed to master the right amount of crunch and seasoning, both of which were absent from Shake Shackas iteration.","• F for raw eggs, fish, and meat raised for food while a 3-log 10 reduction in the Salmonella species takes 1.6 minutes using the D-and z-values in (FDA, 2009, 3-401.11 .B.2).","And no matter how long they may or may not remain in a refrigerator before being reheated, they taste as if youave just ordered them. McDonaldas remains the champion of the nugget world because itas managed to master the right amount of crunch and seasoning, both of which were absent from Shake Shackas iteration. If it ainat broke, donat fix it a and McDonaldas McNuggets are far from broken.","• C/145 • F for raw eggs, fish, and meat raised for food while a 3-log 10 reduction in the Salmonella species takes 1.6 minutes using the D-and z-values in (FDA, 2009, 3-401.11 .B.2). For immuno-compromised people, most experts recommend a 6.5-7-log 10 reduction of the Salmonella species and a 5-log 10 reduction of pathogenic strains of E. coli; Figure 5 shows a plot of experimentally determined times and temperatures for a 7-log 10 reduction in the Salmonella species, a 6-log 10 reduction in L. monocytogenes, and a 5-log 10 reduction in the pathogenic strains of E. coli.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_352,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.","The ordinary free energy continues to govern whether a thermodynamical transition is possible, while the Rényi-divergences do not.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","In this case, we recover the second laws as stated above. The ordinary free energy continues to govern whether a thermodynamical transition is possible, while the Rényi-divergences do not. We thus see that the ordinary second law can arise in the macroscopic limit, or if we allow processes which deviate from being cyclic in a manner which is constant per number of particles in the working body.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_353,"Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains.",• F: the protein ovomucoid denatures and causes the egg white to form a firm gel (the egg yolk also coagulates around this temperature) ; and • 84.5 • C/184,"Bringing McNuggets to a work meeting isnat a great idea, either. Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains. Theyare also a little juvenile in their small boxes, which means your co-workers wonat take you seriously when you have something to say.",• C/158 • F: the protein ovomucoid denatures and causes the egg white to form a firm gel (the egg yolk also coagulates around this temperature) ; and • 84.5 • C/184 Figure 1 shows how even small changes in temperature visibly change the texture of the yolk in eggs cooked for 1 hour.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_354,Chickan Bites from Shake Shack donat microwave well.,• C/158,"McDonaldas, because theyare more delicious. Chickan Bites from Shake Shack donat microwave well. The chicken was still very tough; the residual taste in my mouth still very strong.",• C/148 • C/158 • F: the protein ovomucoid denatures and causes the egg white to form a firm gel (the egg yolk also coagulates around this temperature) ; and • 84.5 • C/184,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1411728112,Computer_Science_easy_355,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","It was shown that in the case of systems of the same size, the class of noisy operations is equivalent to mixtures of unitaries.","Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","However, before we approach this problem, it is instructive to first consider the case where the Hamiltonian is trivial in the sense that H = 0, and thermodynamics is reduced to bare information theory. It was shown that in the case of systems of the same size, the class of noisy operations is equivalent to mixtures of unitaries. Therefore the condition that ρ can be transformed into ρ is equivalent to majorization: ρ can be transformed into ρ iff the spectrum of ρ majorizes the spectrum of ρ [43] .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.compag.2016.07.028,Computer_Science_easy_356,"Now there are thousands of measurements that are, in principle, equally easy to make.",The prediction is more accurate for B73 than FFMM-A.,"""The exciting thing here is that there are now so many things that we could potentially measure. Now there are thousands of measurements that are, in principle, equally easy to make. It's a very good problem to have.""","Plant water content can be satisfactorily predicted with the reflectance spectra extracted from plant hyperspectral images. The prediction is more accurate for B73 than FFMM-A. This is due to the fact that, at the late growth stage, FFMM-A plants exhibit more complex plant structure and develop reproductive organs with different spectral signatures from plant leaves.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1145/2872427.2883081,Computer_Science_easy_357,"Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","However, in terms of word ratios, definite articles (e.g., ""the"" instead of ""a"") are preferred, which suggests that specificity is important in persuasive arguments.","ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason. Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","These are highly correlated with length, so they are both highly significant in terms of absolute numbers. However, in terms of word ratios, definite articles (e.g., ""the"" instead of ""a"") are preferred, which suggests that specificity is important in persuasive arguments. In absolute numbers, successful arguments are more sentiment-laden in both root reply and full path.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_359,"Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.",The special case of α = 1 is also proven in .,"In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered.","In the range of α ∈ [0, 1], (E21) is obtained by the joint convexity of the Rényi divergence, as proven in Theorem 11 of [37] . The special case of α = 1 is also proven in . For any two sets of distributions (A 1 , B 1 ) and (A 2 , B 2 ), and a parameter 0 < δ < 1, the Rényi divergence in this range of α satisfies",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2560/13/2/026017,Computer_Science_easy_360,"""This precision is what allowed us to separate the control of individual fingers.""",Using HGWs as features contradicts a key conditional independence assumption of the HMM architecture utilized by the Viterbi decoder which states that,"""The electrodes used to measure brain activity in this study gave us better resolution of a large region of cortex than anything we've used before and allowed for more precise spatial mapping in the brain,"" says Guy Hotson, graduate student and lead author of the study. ""This precision is what allowed us to separate the control of individual fingers."" Initially, the mind-controlled limb had an accuracy of 76 percent.","Thus, HGWs represent the responses both spatially (by using multiple electrodes) and temporally (by including multiple points in time). Using HGWs as features contradicts a key conditional independence assumption of the HMM architecture utilized by the Viterbi decoder which states that For example, the grid search results for subject A indicate that the optimal HGW for a phoneme occurring at time t contains the high gamma activity values for each relevant electrode at the time points occurring 70, 130, 190, and 250 milliseconds after t. For later comparison against the system's performance when using the optimal HGW, we also determined the optimal HGS for each subject.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/mrDnGISKYr4/
10.1073/pnas.1411728112,Computer_Science_easy_362,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","However, in models where the Hamiltonian is trivial, i.e.","Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","This is because transitions between pure states are not effected by catalysis. However, in models where the Hamiltonian is trivial, i.e. H = 0, one needs an alternative way to define work.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_364,"The winner: McDonaldas Chicken McNuggets

Everything about Shack Shakeas chicken nuggets is great, in theory.",• 61.5,"Theyare also a little juvenile in their small boxes, which means your co-workers wonat take you seriously when you have something to say. The winner: McDonaldas Chicken McNuggets

Everything about Shack Shakeas chicken nuggets is great, in theory. Fresh, antibiotic-free chicken breast you can order from an iPad a whatas not to love?",The fast changes happen quickly when the temperature of the food exceeds a certain threshold. • 61.5 • C/143,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1098/rspb.2019.0646,Computer_Science_easy_365,"That's been a tough nut to crack.""",These findings suggest that improving our understanding of the situations in which imperfect camouflage can offer protection may help conservationists decide how best to protect threatened species.,"Their study is published in the Proceedings of the Royal Society B.

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The team's research builds on a study Hughes conducted several years ago that found that guppies' color patterns did seem to influence mate choice. That's been a tough nut to crack."" The researchers found that females typically preferred the novel male guppies.","This translocation therefore potentially reduced genetic diversity, which may have important consequences for conservation, particularly in cases where populations are already small. These findings suggest that improving our understanding of the situations in which imperfect camouflage can offer protection may help conservationists decide how best to protect threatened species. Similarly to camouflage, these conspicuous colour signals can also be considered within a generalist or specialist adaptation framework.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1073/pnas.1411728112,Computer_Science_easy_366,It's possible we will find all the coins landing tails.,"All the functions f α are strictly Schur convex, so we have f α (x) > f α (y ).","However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","We have that y ↓ = y ↓ , and y ↓ y ↓ . All the functions f α are strictly Schur convex, so we have f α (x) > f α (y ). Therefore, x can be trumped into y, i.e.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_367,"Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do.",• C/175,"aGiven the choice between reliving the warthog experience and eating a McNugget, Iam surely eating the McNugget,a Bourdain told AV Club in 2008. aBut at least I knew what the warthog was. Whereas with the McNugget, I think thatas still an open question.a

No one really knows where chicken nuggets come from, what theyare made of or why they look the way they do. In my eyes, no moment in adulthood comes close to a Saturday afternoon spent with my parents, buying several boxes of McNuggets in the hopes of finding a Boardwalk piece a the key to winning the $1 million prize in McDonaldas Monopoly game.","• F and can significantly tenderize the meat if held for more than 6 hours (Tornberg, FDA, 2011) . • C/175 • C/127-131",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1145/2872427.2883081,Computer_Science_easy_368,"Emotions like anxiety, fear, and anger exacerbate political bias, so use soft wording and a calm tone, and try to make them feel at ease.",Early entry is more likely to win a delta.,"Avoid using emotionally-charged words and approach them in a way that does not feel threatening. Emotions like anxiety, fear, and anger exacerbate political bias, so use soft wording and a calm tone, and try to make them feel at ease. When challenging their views, don't try to belittle or insult them by calling them dumb or ignorant.",Figure 4: Figure 4a shows the ratio of a person eventually winning a delta in a post with at least 10 challengers depending on the order of her/his entry. Early entry is more likely to win a delta. Figure 4b presents the probability of winning a delta given the number of comments by a challenger in a back-and-forth path with OP.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1073/pnas.1411728112,Computer_Science_easy_370,"For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.",This happens when the catalyst's dimension is free to be arbitrarily large.,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","for all real α which is equivalent to (F2). This happens when the catalyst's dimension is free to be arbitrarily large. In such cases, fidelity is not a good criterion for closeness any more (we discuss this in more detail in Section G of the Supplementary Information).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_371,"However, this is not true when tossing the coin just a few times.",One easily finds that indeed this is a valid conditional probability distribution.,"In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails.","This implies that E C = E C . One easily finds that indeed this is a valid conditional probability distribution. By continuity, the conditions can equivalently include α = ∞, −∞.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_372,"In this case, we expect to see roughly equal numbers of heads as tails.","If we take ≥ e −βE Z , we have ||ρ − ρ β || 1 ≤ .","They showed that not only does entropy increase, but other types of disorder also have to increase. In this case, we expect to see roughly equal numbers of heads as tails. However, this is not true when tossing the coin just a few times.","However as we will discuss in section G, if there are no further restrictions on the available catalyst, then closeness in trace distance is not a suitable demand on the returned catalyst in thermodynamic transformations. If we take ≥ e −βE Z , we have ||ρ − ρ β || 1 ≤ . On the other hand, for any α > 1, if we set e.g.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1145/2872427.2883081,Computer_Science_easy_373,"Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length.","ADVERTISEMENT

By carefully building these bridges, we can come closer to agreement rather than pushing one another further away. Of course, there are limits to how much time and energy one can spend on trying to convince someone who completely refuses to listen to reason. Move on to the next irrational American that needs saving, because the war against ignorance and intolerance is one we must face head on.","This is not surprising: longer replies can be more explicit and convey more information. But naïvely making a communication longer does not automatically make it more convincing (indeed, sometimes, more succinct phrasing carries more punch); our more advanced features attempt to capture the subtler aspects of length. The descending concreteness trend suggests that opinions tend to be expressed in a particular-to-general way; replies notably differ by having both the opening and the closing be abstract, with a concrete middle.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34825237314&p=1pl&v=1&x=Ek2kCrlRC5EYJ6uvaCrODQ
10.1098/rstb.2008.0288,Computer_Science_easy_374,"That's a big deal.""",Professional musicians were also found to show enhanced judgements of line orientation and three-dimensional mental rotation ability ( ( .,"""But it turns out it really was the training process that caused the growth in the brain. It shows you can produce profound changes in the brain with training. That's a big deal.""","Structural brain changes associated with learning over a time scale of years, however, seem to be restricted to taxi drivers and the acquisition of a large, integrated and complex spatial layout (see for effects relating to short time scales). Professional musicians were also found to show enhanced judgements of line orientation and three-dimensional mental rotation ability ( ( . This was attributed to their musical sight-reading and motor sequencing expertise.",[1],Computer_Science,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1073/pnas.1411728112,Computer_Science_easy_375,"It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself.","This shows that if we relax the conditions on how cyclic the process is, by allowing relatively large inaccuracies in the returned catalyst, then we recover the usual second law.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","In particular, we will see that in the extensive regime only the Shannon entropy matters, and the Rényi entropies are no longer relevant. This shows that if we relax the conditions on how cyclic the process is, by allowing relatively large inaccuracies in the returned catalyst, then we recover the usual second law. with h(x) := −x log(x) − (1 − x) log(1 − x) the binary entropy.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1098/rspb.2019.0646,Computer_Science_easy_376,"That's been a tough nut to crack.""","In a natural situation, this could suggest that generalist strategies will be more likely when predators repeatedly encounter the same prey types.","Their study is published in the Proceedings of the Royal Society B.

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The team's research builds on a study Hughes conducted several years ago that found that guppies' color patterns did seem to influence mate choice. That's been a tough nut to crack."" The researchers found that females typically preferred the novel male guppies.","However, for later presentations, the compromise and specialist prey were equally difficult. In a natural situation, this could suggest that generalist strategies will be more likely when predators repeatedly encounter the same prey types. Overall, it is plausible that both compromise and specialist camouflage strategies can be good solutions, depending upon background properties, as predicted by theoretical modelling.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39231165247&p=1pl&v=1&x=YiytxbCM3laBXxUWdpYKGQ
10.1073/pnas.1411728112,Computer_Science_easy_378,"The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","As before, by using a pure state which is returned arbitrarily close to pure, we will automatically satisfy Equation (F17) for α ≤ 0 and we may thus only consider 0 ≤ α ≤ 2.","It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena. ""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases.""","The reason for considering condition (F16) only for 1 2 ≤ α ≤ 1, is that for α ≥ 1, the entropies would diverge for non full rank catalyst, so may not be monotones if we use such catalysts. As before, by using a pure state which is returned arbitrarily close to pure, we will automatically satisfy Equation (F17) for α ≤ 0 and we may thus only consider 0 ≤ α ≤ 2. These conditions are like second laws, in that they are necessary conditions which must be respected during a thermodynamic transition, however, they are not sufficient.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_379,"Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated.",The result of [4] gave a thermodynamic interpretation to the notion of negative information [49] .,"Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws. Stranger still, the way these second laws interact with each other can even make it look like the traditional second law has been violated. For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change.","This can be seen as a fully quantum version of the standard Maxwell demon/Landauer erasure scenario, and has been considered in the case of a trivial Hamiltonian [4, 9] and when the Maxwell demon does not have access to ancilliary systems. The result of [4] gave a thermodynamic interpretation to the notion of negative information [49] . We will see here, that the amount of work which is required for such an operation, is quantitatively different when all thermodynamical operations are considered.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_380,"These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important.","Rather than a single free energy which determines which transitions are possible, we find necessary and sufficient conditions for thermodynamic transitions which form, not just one, but a family of second laws.","These new second laws are generally not noticeable except on very small scales, at which point, they become increasingly important. It tells us that a hot cup of tea in a cold room will cool down rather than heat up; that even the most efficient machines will lose some energy as heat; and more prosaically, that a house will gradually get messier over time rather than tidying itself. The research, published in the journal Proceedings of the National Academy of Sciences, reveals that on very small scales there is actually a whole family of 'second laws', which can lead to unexpected and counterintuitive phenomena.","Here we consider all possible cyclic thermodynamical processes, and show that transition laws are affected by using ancillary systems which are returned back to their initial state. Rather than a single free energy which determines which transitions are possible, we find necessary and sufficient conditions for thermodynamic transitions which form, not just one, but a family of second laws. We can then state quantum second laws, and ones that hold for states block diagonal in the energy basis.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1088/1741-2552/aabc9b,Computer_Science_easy_381,"The findings, Swann says, lay the groundwork for more complex algorithms to achieve that balance in improved versions of the device.","The narrowband gamma signal related to dyskinesia occurs at half the stimulation frequency, when dyskinesia is present ( Figure 1A and 1C) .","Researchers saw energy savings of 39 percent and 45 percent in the devices when using the adaptive algorithms. The findings, Swann says, lay the groundwork for more complex algorithms to achieve that balance in improved versions of the device. ""Ultimately, this could be customized for each person to keep them in their ideal brain state,"" Swann says.","(For instance, constant current was not used for algorithm prototyping due to artifacts associated with this mode .) The narrowband gamma signal related to dyskinesia occurs at half the stimulation frequency, when dyskinesia is present ( Figure 1A and 1C) . Stimulation parameters used for adaptive DBS are shown in",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-brain-stimulation-parkinsons-disease-1761562/
10.1073/pnas.1411728112,Computer_Science_easy_382,It's possible we will find all the coins landing tails.,where ||ρ out S − ρ S || ≤ .,"However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","Conversely, let us assume that for given states ρ S and ρ S there exists a quantum channel Λ, and a system C with the hamiltonian H C , and state ρ C such that where ||ρ out S − ρ S || ≤ . Now, let us note that by thermal operations, one can make any state diagonal in the energy basis, namely one can apply random phases (by using the Birkhoff primitive of which supplies random noise and unitaries that change phases).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1073/pnas.1411728112,Computer_Science_easy_383,It's possible we will find all the coins landing tails.,"However in other cases, we find that one can distill more work than would be obtainable without considering an ancillary system which is used as a catalyst.","However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","We thus see that the Helmholtz free energy and two free energies proposed in [5] are special cases of our family of conditions and they hold even in the presence of catalysts. However in other cases, we find that one can distill more work than would be obtainable without considering an ancillary system which is used as a catalyst. As a simple application of our results, we find that by using an ancillary system, one can erase or reset a memory register at a lower work cost than previously known.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_385,"McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor.",• C/131,"The chicken was still very tough; the residual taste in my mouth still very strong. McNuggets can be reheated and still taste very much the same, but are best prepared in the oven to maintain that necessary crunch-factor. McNuggets are preserved enough to sustain themselves through an apocalypse and still taste like theyare fresh out of the fryer.","The color of meat cooked to the same temperature depends on how quickly it reaches that temperature and on how long it's held at that temperature: the faster it comes up to temperature, the redder it is; the longer it's held at a particular temperature, the paler it becomes ; see Figure 3 for meat cooked at 55 • C/131 The muscle fibers start to shrink at 35-40",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1016/j.robot.2015.01.003,Computer_Science_easy_387,Probably none of these.,It thus does not fit our definition.,"As a consequence, a frog's notion of space will most likely differ from that of a bat, which will in turn differ from that of humans. Probably none of these. If we want robots to be truly intelligent, we should not build them using abstract notions, but instead, provide them with algorithms that will allow them to develop such notions themselves.""","But those constraints are so trivial that they do not stimulate the agent to capture any underlying structure in its experience. It thus does not fit our definition. For the example under consideration, the two motor commands m 1 and m 2 are redundant in determining the agent's position x in space .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37406801001&p=1pl&v=1&x=ssZ2MTLzJwq_5rjL57WYwg
10.1073/pnas.1411728112,Computer_Science_easy_388,"""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","Clearly, this unitary acted upon the initial joint state ρ A k ⊗ |m m| B extracts ω ≥ 0 amount of work into the battery system with probability p i , and − ω with probability p j , while the expectation value of work extracted is given by the difference in expected energy in the battery system,","It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles."" Professor Oppenheim added: ""While a quantum house will get messier rather than tidier, like a normal house, our research shows that the ways in which it can get messier are constrained by a range of extra laws.","Then by the definition of passivity, there exists some i, j where E i > E j , p i > p j holds. Clearly, this unitary acted upon the initial joint state ρ A k ⊗ |m m| B extracts ω ≥ 0 amount of work into the battery system with probability p i , and − ω with probability p j , while the expectation value of work extracted is given by the difference in expected energy in the battery system, Now, similarly, consider the initial state ρ A1 ⊗ · · · ⊗ ρ Am ⊗ |m m| B , and the unitary transformation U m · · · U 1 .",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_390,"The skin, which offers a slight crunch when prepared perfectly, is the best part.",These mutagens depend strongly on both temperature and time: they increase almost linearly in time before leveling off (after 5-10 minutes); an increase in temperature of 25,"Itas hard to eat more than a few at a time because of the overwhelming seasoning. The skin, which offers a slight crunch when prepared perfectly, is the best part. The meat is light, a little salty and, of course, very greasy.",• F can significantly increase the production of mutagens. These mutagens depend strongly on both temperature and time: they increase almost linearly in time before leveling off (after 5-10 minutes); an increase in temperature of 25 • F) roughly doubles the quantity of mutagens .,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1038/s41598-018-30656-7,Computer_Science_easy_391,"aIt is possible that this can only be done by some form of mental simulation of the outcome.a

Experimental setup in the construction test.","Colonies, in contrast, took a significantly shorter time for the binary choice than they did when given a single nest (p = 0.04), thus agreeing with the SCM (Fig.","This suggests that compound tool making is a cognitively difficult step a and makes it all the more impressive that Mango and his friends figured it out. aIt is possible that this can only be done by some form of mental simulation of the outcome.a

Experimental setup in the construction test. Neither of these items was long enough on its own, but combined, they could become a far-reaching tool.","When both nest types were present, individuals took significantly longer to make a choice than they did in the presence of a single option of either type (p = 0.04), consistent with the ToW model (Fig. Colonies, in contrast, took a significantly shorter time for the binary choice than they did when given a single nest (p = 0.04), thus agreeing with the SCM (Fig. The poor nest was chosen in about 16% and 18% of binary cases for individuals and colonies, respectively.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1073/pnas.1411728112,Computer_Science_easy_392,"The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder.","The maps Γ and Γ * are channels, and for all probability distributions p we have Γ * (Γ(p)) = p. Moreover, for the specific state γ = { d1 N , .","""These additional second laws, can be thought of as saying that there are many different kinds of disorder at small scales, and they all tend to increase as time goes on,"" said co-author Professor Michal Horodecki (Gdansk). The researchers found additional measures of disorder, all different to the standard entropy, which quantify different types of disorder. They showed that not only does entropy increase, but other types of disorder also have to increase.","with eachp The maps Γ and Γ * are channels, and for all probability distributions p we have Γ * (Γ(p)) = p. Moreover, for the specific state γ = { d1 N , . is the uniform N -dimensional distribution.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1038/s41598-018-30656-7,Computer_Science_easy_393,"When the scientists made the task more difficult by supplying three or four combinable parts, Mango was the only one that figured it out.","In any event, if such signals do play a role, their consequences are not sufficient to override the fast decisions that derive from processing multiple options in parallel.","Four of the crows figured out how to do it. When the scientists made the task more difficult by supplying three or four combinable parts, Mango was the only one that figured it out. But the team thinks that the crowsa natural propensity to use tools and their ability to determine which objects can be used as tools certainly help.","It may be that they are deployed only seasonally, as appears to be the case for T. albipennis 37 , or only for sites worse than those presented here. In any event, if such signals do play a role, their consequences are not sufficient to override the fast decisions that derive from processing multiple options in parallel. Similarly, it is not necessarily true that individual decisions must follow the ToW model, and could never fit the predictions of the SCM, because of being unable to make simultaneous comparisons.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_394,A little research on the company's website should tell you what the bags are made of.,• C/34-38,"That may be so, but it isn't any more likely than with vacuum bags designed for sous vide cooking -- they are made out of the exact same kind of plastic. A little research on the company's website should tell you what the bags are made of. High-density polyethylene, low-density polyethylene and polypropylene are the safest plastics to cook with.",Recall that enzymes make up a significant portion of the sarcoplasmic proteins. • C/34-38 • C/113,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33741545788&p=1pl&v=1&x=9uqc0T6o3042BlRx7tCbiA
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_395,"Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains.","• F, so the vapor pressure of water is below 12 mbar/0.2 psi, then recommends using a 90-95% vacuum when using a chamber vacuum sealer recommend vacuum-sealing at a pressure of 30-50 mbar/0.4-0.7 psi; these vacuum sealing pressure seem to keep the texture of the food from being damaged and usually prevent the vacuum-sealed pouches from floating during cooking.","Bringing McNuggets to a work meeting isnat a great idea, either. Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains. Theyare also a little juvenile in their small boxes, which means your co-workers wonat take you seriously when you have something to say.","• C/50 • F, so the vapor pressure of water is below 12 mbar/0.2 psi, then recommends using a 90-95% vacuum when using a chamber vacuum sealer recommend vacuum-sealing at a pressure of 30-50 mbar/0.4-0.7 psi; these vacuum sealing pressure seem to keep the texture of the food from being damaged and usually prevent the vacuum-sealed pouches from floating during cooking. Both also recommend using the water-displacement-method for sealing food in Ziploc R ⃝ (or similar quality re-sealable storage) bags; this has the advantages of not damaging the texture of food or requiring expensive equipment.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1073/pnas.1419704112,Computer_Science_easy_396,"Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar.","Polynesia was largely peopled through relatively small numbers of colonists making ocean voyages and establishing new settlements on uninhabited islands (37, 57).","So it seems possible that with the globalisation made possible through the Internet, the English language should be changing at a faster rate than ever before. Whether that's the case, we're certainly seeing a lot of new additions to dictionaries, and a lot of those new additions are slang terms with which your average Internet denizen will be pretty familiar. This quarter's update shows that contemporary culture continues to have an undeniable and fascinating impact on the language.""","In this case, we might consider each language group to be an independent experiment in language evolution, triggered by the establishment of a new population on an uninhabited island. Polynesia was largely peopled through relatively small numbers of colonists making ocean voyages and establishing new settlements on uninhabited islands (37, 57). Therefore, we expect that each language group was started by a relatively small founding population that then grew in size.",[1],Computer_Science,train,1.0,news,http://www.cnet.com/news/hangry-redditor-rage-quits-cat-cafe-all-enter-oxford-dictionary/
10.1016/j.ijgfs.2011.11.002,Computer_Science_easy_399,"Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains.","The color of meat cooked to the same temperature depends on how quickly it reaches that temperature and on how long it's held at that temperature: the faster it comes up to temperature, the redder it is; the longer it's held at a particular temperature, the paler it becomes ; see Figure 3 for meat cooked at 55","Bringing McNuggets to a work meeting isnat a great idea, either. Theyare a little greasy, so you wouldnat be able to write anything down or type on a laptop without leaving stains. Theyare also a little juvenile in their small boxes, which means your co-workers wonat take you seriously when you have something to say.","Note that while two similar cuts cooked to the same internal temperature will have a similar plumpness and juiciness, their color may be different. The color of meat cooked to the same temperature depends on how quickly it reaches that temperature and on how long it's held at that temperature: the faster it comes up to temperature, the redder it is; the longer it's held at a particular temperature, the paler it becomes ; see Figure 3 for meat cooked at 55 • C/131",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37177682260&p=1pl&v=1&x=xtiqWbx0klqzjo_iio1TzQ
10.1186/s12918-019-0687-x,Computer_Science_easy_400,The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of genes for the components of JAK/STAT pathway.,The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of the JAK/STAT target genes domeless and Socs36E.,Conditional overexpression of upd1 in different tissues of Drosophila induces pro-aging or pro-longevity effects in tissue-dependent manner. The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of genes for the components of JAK/STAT pathway. As the JAK/STAT pathway is evolutionarily conserved it may be possible to discover compounds that fit the criteria of geroprotector.,"Thus, conditional overexpression of the upd1 gene encoding a JAK/STAT signaling ligand results in alteration of the Drosophila lifespan depending on the tissue specificity of overexpression. The effects of upd1 overexpression on lifespan are accompanied by the transcription activation of the JAK/STAT target genes domeless and Socs36E. As the JAK/STAT pathway is evolutionarily conserved it may be possible to discover compounds that fit the criteria of geroprotector .",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=38925560223&p=1pl&v=1&x=DS4iY-yA6FXi5JkR1N2Hhg
10.1073/pnas.1810287115,Computer_Science_easy_401,"The hybrid prevalence estimate can be used to validate and then, if necessary, moderate HIS administrative estimates of coverage.","By combining the probability survey and HIS data, a hybrid prevalence estimate can be generated that can be used to validate and/or moderate HIS administrative estimates of coverage.","It is not representative of the population's health as it reports the health behaviour of people who attend the clinics. The hybrid prevalence estimate can be used to validate and then, if necessary, moderate HIS administrative estimates of coverage. This allowed for more accurate health information than utilising source data alone.","Although these are a major advance, they are not well suited to drive operational policy decisions and detect gaps in service coverage. By combining the probability survey and HIS data, a hybrid prevalence estimate can be generated that can be used to validate and/or moderate HIS administrative estimates of coverage. The denominator of each targeted age group differs for the two campaigns; the VAS denominator is estimated from the 1993 census data and extrapolated with a population growth rate of 2.8% (13), whereas the polio campaign denominator uses the number of children reached during the previous polio campaign.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=37918205357&p=1pl&v=1&x=Wykbcl8upHeIAtx6SQVHYQ
10.1038/s41598-018-31632-x,Computer_Science_easy_402,"""Such ubiquitous blood pressure monitoring may improve hypertension awareness and control rates, and thereby help reduce the incidence of cardiovascular disease and mortality.""",Such ubiquitous BP monitoring may improve hypertension awareness and control rates and thereby help reduce the incidence of cardiovascular disease and mortality.,"""Such ubiquitous blood pressure monitoring may improve hypertension awareness and control rates, and thereby help reduce the incidence of cardiovascular disease and mortality."" ""If things keep moving along at the current pace, an app could be available in late 2019,"" Professor Mukkamala said. ""Like our original device, the application still needs to be validated in a standard regulatory test.""","In summary, this proof-of-concept study surprisingly indicates that cuff-less and calibration-free BP monitoring may be feasible with many existing and forthcoming smartphones by leveraging sensors built-in for other purposes. Such ubiquitous BP monitoring may improve hypertension awareness and control rates and thereby help reduce the incidence of cardiovascular disease and mortality. After excluding two outlier data points, each set of 20 data points appeared to be well fit by a line.",[5],Computer_Science,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/iO6DRNBUAFg/blood-pressure-app-06394.html
10.1021/acscentsci.9b00055,Computer_Science_easy_404,"""We expect that our retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts,"" Bishop notes.","Looking forward, we anticipate that the retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts.","The researchers are also trying to reduce the number of simulations required for the model to learn its strategy, as the training process was quite computationally expensive. ""We expect that our retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts,"" Bishop notes. ""And we welcome competition.","This approach is conceptually similar to the first iteration of AlphaGo introduced by DeepMind. Looking forward, we anticipate that the retrosynthesis game will soon follow the way of chess and Go, in which self-taught algorithms consistently outperform human experts. in the SMILES string).",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=39395282428&p=1pl&v=1&x=CkWENAh0Nhy_OGKwvj59yQ
10.1038/s41598-018-38277-w,Computer_Science_easy_405,"When movements were based on haptic information only, hand pre-shaping was initiated earlier, fingers closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information.","When movements were based on haptic information only, hand preshaping was initiated earlier, the digits closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information.","When movements were based on haptic information only, hand pre-shaping was initiated earlier, fingers closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information. Instead, the simultaneous availability of vision and haptics led to faster movements and to an overall decrease of the grip aperture. ""Our findings also show that each modality contributes to a different extent in different phases of the movement, with haptics being more crucial in the initial phases and vision being more important for the final on-line control,"" said Volcic.","However, planning and execution of grasping movements can be supported also by haptic information when we grasp objects held in the other hand. When movements were based on haptic information only, hand preshaping was initiated earlier, the digits closed on the object more slowly, and the final phase was more cautious compared to movements based on only visual information. Importantly, the simultaneous availability of vision and haptics led to faster movements and to an overall decrease of the grip aperture.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=38714544745&p=1pl&v=1&x=J2fRXfohz--Y2qLyaVBfzQ
10.1140/epjds/s13688-019-0191-y,Computer_Science_easy_406,"""The residents of Hackney, which is a deprived yet highly-educated neighbourhood in East London, enjoy healthier eating habits and do not suffer from diabetes as much as Newham's residents,"" say Aiello and co.","deprived yet highly-educated neighborhood in East London, enjoy healthier eating habits (i.e., low consumption of carbohydrates and high nutrient diversity) and do not suffer from diabetes as much as Newham's residents do.","By contrast, residents of Newham, a relatively deprived neighborhood, consume more calories and less diverse nutrients, and they have higher levels of diabetes. ""The residents of Hackney, which is a deprived yet highly-educated neighbourhood in East London, enjoy healthier eating habits and do not suffer from diabetes as much as Newham's residents,"" say Aiello and co. Indeed, they say their classifier can identify unhealthy areas with an accuracy of 91%.","This is further confirmed by the quadrant in Figure 6 , which places areas according to the prevalence of pairs of nutrients (computed with Formulae (3), (4), and (5)), and colors them according to the prevalence of diabetes (computed with Formula (1)): residents of the City (central London) and Chelsea (West London), who tend to be highly educated and well-off, consume fibres and diversify nutrients; those of Newham, which is a deprived yet rapidly developing neighborhood in East London, consume considerable quantities of calories, do not diversify their nutrients, and end up with a high prevalence of diabetes; interestingly, the residents of Hackney, which is a Figure 4 The relationship between hypertension, cholesterol, and diabetes (columns) and food-related metrics (rows). deprived yet highly-educated neighborhood in East London, enjoy healthier eating habits (i.e., low consumption of carbohydrates and high nutrient diversity) and do not suffer from diabetes as much as Newham's residents do. However, these metrics are not orthogonal, and the presence of one is generally associated with the presence of another.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=39248237949&p=1pl&v=1&x=K8-9kAHl1jwYlx5yTlVwPg
10.5772/58730,Computer_Science_easy_407,"In comparison to other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform, costing around PS25, making the replication of swarm behaviour in large numbers of robots more feasible and economical for researchers.","In comparison to the other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform (about £25) and hence it is feasible for the easy and economic replication of large numbers of robots.","Its small size (4cm diameter) and fast motion (35cm/s) means it can be used in fast-paced swarm scenarios over large areas. In comparison to other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform, costing around PS25, making the replication of swarm behaviour in large numbers of robots more feasible and economical for researchers. This concept allows for the coordination of simple physical robots in order to cooperatively perform tasks.","The design of Colias was considered in terms of these requirements and, due to its small size and fast motion, experiments could be conducted both cost-and time-effectively in a small working area. In comparison to the other mobile robots which are utilized in swarm robotic research, Colias is a low-cost platform (about £25) and hence it is feasible for the easy and economic replication of large numbers of robots. The parallel processing provides for the fast and reliable control of different functions of the robot.",[5],Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2014/09/140918111152.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1145/2733373.2809930,Computer_Science_easy_408,"""For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, grey, and black colors,"" they say.","For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, gray and black colors.","The algorithm found that a small number of classic outfit styles are common every year. ""For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, grey, and black colors,"" they say. But a key point of interest is in how fashions change and the algorithm helps here too.","We observe that there are always some classic colors, patterns or styles that have a large amount of clothing images in the fashion shows of every year. For example, in upper body color, both 2014 and 2015 fashion images have a large amount of white, gray and black colors. These examples indicate that the results generated by attribute description methods are very reasonable and these results can be a very significant reflection for the fashion shows styles.",[5],Computer_Science,train,5.0,news,http://www.technologyreview.com/view/541091/how-machine-vision-is-about-to-change-the-fashion-world/
10.1145/2441776.2441938,Computer_Science_easy_409,"The biggest spike in Monterrey consisted of over 7,027 tweets on August 25, 2011, when an attack at a casino left 53 people dead.","The biggest spike in Monterrey (7,027 tweets) occurred on August 25, 2011, the day of an attack at a casino where 53 people were killed .","The team also found that the number of tweets spikes when violence strikes and drops when the cities are calm. The biggest spike in Monterrey consisted of over 7,027 tweets on August 25, 2011, when an attack at a casino left 53 people dead. However, a small fraction of these people tweeted more than 1,000 messages each.","Second, we found that the number of daily tweets goes up and down constantly, spiking when violence erupts and decreasing when the city is calm (see Figure 1 ). The biggest spike in Monterrey (7,027 tweets) occurred on August 25, 2011, the day of an attack at a casino where 53 people were killed . For Veracruz, the biggest spike (4,699 tweets) also happened on August 25, 2011, during a seemingly unrelated event, when rumors of school children being kidnapped spread on social media .",[5],Computer_Science,train,5.0,news,http://www.technologyreview.com/view/539406/the-rise-of-the-urban-war-correspondent-on-twitter/
10.1073/pnas.1322705111,Computer_Science_easy_410,"The results from these three lines of evidence were highly convergent, suggesting that all such diverse phenomena as the acoustics of the human ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation ultimately reflect the adaptation of human hearing to the statistics of natural auditory scenes.","This suggests that all such diverse phenomena, such as the convoluted shape of the outer ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation, ultimately reflect adaptation to the statistics of natural auditory scenes.","First of all, they recorded and analyzsed a large sample of sounds from the natural environment and found that high frequency sounds are more likely to originate from high positions in space. The results from these three lines of evidence were highly convergent, suggesting that all such diverse phenomena as the acoustics of the human ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation ultimately reflect the adaptation of human hearing to the statistics of natural auditory scenes. 'These results are especially fascinating, because they do not just explain the origin of the mapping between frequency and elevation,' says Parise, 'they also suggest that the very shape of the human ear might have evolved to mirror the acoustic properties of the natural environment.","In this paper we show that pitch borrows its spatial connotation from the statistics of natural auditory scenes. This suggests that all such diverse phenomena, such as the convoluted shape of the outer ear, the universal use of spatial terms for describing pitch, or the reason why high notes are represented higher in musical notation, ultimately reflect adaptation to the statistics of natural auditory scenes. We find that auditory scene statistics reveals a clear mapping between frequency and elevation.",[5],Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2014/04/140408111431.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1145/3184558.3191531,Computer_Science_easy_411,"That was 2.4 times higher than on Twitter, but 2.2 times lower than on 4chan's ""Politically Incorrect board.""","This is 2.4 times higher than on Twitter, but 2.2 times lower than on 4chan's Politically Incorrect board (/pol/) .","""Technology companies need to work harder and faster to curb the vicious violence-inducing harassment on their platforms."" About 5 percent of Gab's posts included hate words, according to the study. That was 2.4 times higher than on Twitter, but 2.2 times lower than on 4chan's ""Politically Incorrect board.""","Hate speech is extensively present on the platform, as we find that 5.4% of the posts include hate words. This is 2.4 times higher than on Twitter, but 2.2 times lower than on 4chan's Politically Incorrect board (/pol/) . In summary, our analysis highlights that Gab appears to be positioned at the border of mainstream social networks like Twitter and ""fringe"" Web communities like 4chan's /pol/.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=37536752662&p=1pl&v=1&x=duEiFGh3B8IyZZsh6hnLOA
10.1073/pnas.1501444112,Computer_Science_easy_412,"The prevalence of these formidable ties suggests they might arise from career strategies based upon cost, risk and reward sharing, as well as complementary skill matching.","The prevalence of super ties suggests that they arise from career strategies based upon cost, risk, and reward sharing and complementary skill matching.","""We find that super-ties contribute to above-average productivity and a 17 percent citation increase per publication, thus identifying these partnerships - the analog of life partners - as a major factor in science career development,"" wrote Petersen. The prevalence of these formidable ties suggests they might arise from career strategies based upon cost, risk and reward sharing, as well as complementary skill matching. The study also highlights a common problem in scientific publications, namely the tendency of some researchers to game the system by doing just enough work to get their names on as many papers as possible, thereby boosting their resumes and, subsequently, their careers in a particular field.","This process can be influenced by strategic motivations, as early career researchers are pursuers, whereas senior researchers are typically attractors, of new collaborative opportunities. The prevalence of super ties suggests that they arise from career strategies based upon cost, risk, and reward sharing and complementary skill matching. We find that super ties contribute to above-average productivity and a 17% citation increase per publication, thus identifying these partnerships -the analog of life partners -as a major factor in science career development.",[5],Computer_Science,train,5.0,news,http://www.technology.org/2015/08/12/collaboration-fosters-more-productive-scientific-careers-than-competition/
10.1038/s41558-018-0317-4,Computer_Science_easy_413,"""This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -- instead, it shows that pathways with and without BECCS exist for implementing the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes,"" they write.","This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -instead, it shows that pathways with and without BECCS exist for implementing the goals of the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes.","But the researchers caution that people using the resource should be aware of the limitations of such scenario ensembles, and they set these out explicitly in the Nature Climate Change article. ""This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -- instead, it shows that pathways with and without BECCS exist for implementing the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes,"" they write. The researchers also caution against focusing on the medians, but considering the whole range of possibilities, against cherry picking individual scenarios, and against overinterpreting scenarios that were developed with one specific research purpose.","A number of scenarios show that limiting global warming to 1.5 °C can be achieved without the deployment of BECCS, while the majority of scenarios use it (Fig. This information by itself does not imply that reaching ambitious climate goals is less likely without BECCS -instead, it shows that pathways with and without BECCS exist for implementing the goals of the Paris Agreement, highlighting that different societal preferences and strategies can result in vastly different outcomes. Although it is often easier to communicate single numbers rather than ranges, the full breadth of indicators or trajectories within a scenario set carries important information about the available options (Fig.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=37397753032&p=1pl&v=1&x=K-mv9bWyfvMvWimBmS33TA
10.1098/rsif.2017.0946,Computer_Science_easy_414,We demonstrate that large cities exhibit increased occupational and skill specialization due to increased abundance of managerial and technical professions.,We demonstrate that large cities exhibit increased occupational and skill specialization due to increased abundance of managerial and technical professions.,"Small cities will undertake greater adjustments, such as worker displacement and job content substitutions. We demonstrate that large cities exhibit increased occupational and skill specialization due to increased abundance of managerial and technical professions. Our results pass several robustness checks including potential errors in the estimation of occupational automation and subsampling of occupations.","Small cities will undertake greater adjustments, such as worker displacement and job content substitutions. We demonstrate that large cities exhibit increased occupational and skill specialization due to increased abundance of managerial and technical professions. Our results pass several robustness checks including potential errors in the estimation of occupational automation and subsampling of occupations.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=34275819830&p=1pl&v=1&x=UE_ofw8V_Z5fC_YVu6pQDA
10.1002/adma.201706091,Computer_Science_easy_415,"Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large.","Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large.","The realization of these stable, low-voltage, low-cost, easily transferrable, biocompatible organic electronic devices will pave the way for the development of a new set of point-of-care testing systems, constituted by edible sensors able to effectively operate from within the GI tract. Inherent edibility may also enable the direct integration of electronic sensors into food in the form of embedded smart probes, following a perishable good along its entire lifespan and capable of alerting the consumer when alteration of the properties is taking place. Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large.","Inherent edibility may also enable the direct integration of electronic sensors into food in the form of embedded smart probes, following a perishable good along its entire lifespan and capable of alerting the consumer when alteration of the properties is taking place. Furthermore, being edibility an extreme case of ecocompatibility, the future development of such technology platform will at the same time favor the reduction of the environmental impact of large area and flexible electronics technologies at large. Overall, with our work we take the first step along a promising path and demonstrate that printed polymer electronics is a potential enabler of such an appealing future technology.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=39066321229&p=1pl&v=1&x=AH9tGZ5rqa9mc2sV9F8dEQ
10.1177/1461444814543163,Computer_Science_easy_416,"In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand.","In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand.","Crawford and Gillespie write:

The flag is merely the first step in a process of content regulation, a process that most sites hope either disappears completely beneath the smooth operation of the site, or when it must appear, to present itself as a rational and fair policing mechanism. In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand. Rather than having conversations about flagged content behind closed doors, Crawford and Gillespie propose putting content decisions up for public debate.","The flag is merely the first step in a process of content regulation, a process that most sites hope either disappears completely beneath the smooth operation of the site, or when it must appear, to present itself as a rational and fair policing mechanism. In fact, it benefits social media platforms to retain the ability to make judgments on content removal, based on ad hoc and often self-interested assessments of the case at hand. The opacity of the process means that the site is not obligated to honor the flags it does receive, and that any decision to remove content can be legitimized as being in response to complaints from the community.",[5],Computer_Science,train,5.0,news,http://www.theatlantic.com/technology/archive/2014/08/the-way-we-report-harassment-on-the-social-web-is-broken/378730/
10.1073/pnas.1805122115,Computer_Science_easy_418,"Further, we show that mechanical coupling between connected origami units can be used to program the behavior of a mechanical bit, produce logic gates such as AND, OR, and three input majority gates, and transmit signals between mechanologic gates.","Further, we show that mechanical coupling between connected origami units can be used to program the behavior of a mechanical bit, produce logic gates such as AND, OR, and three input majority gates, and transmit signals between mechanologic gates.","DOI: 10.1073/pnas.1805122115

More information: Benjamin Treml et al. Further, we show that mechanical coupling between connected origami units can be used to program the behavior of a mechanical bit, produce logic gates such as AND, OR, and three input majority gates, and transmit signals between mechanologic gates. Embedded mechanologic provides a route to add autonomy and intelligence in soft robots and machines.","Further, we show that mechanical coupling between connected origami units can be used to program the behavior of a mechanical bit, produce logic gates such as AND, OR, and three input majority gates, and transmit signals between mechanologic gates. Embedded mechanologic provides a route to add autonomy and intelligence in soft robots and machines. We show that mechanical coupling between origami units transfers information and enables creation of mechanical logic gates that can be connected to form reprogrammable mechanologic circuits.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=34352088128&p=1pl&v=1&x=tMEQqJz4R4Q2kl5KfUwkBA
10.1145/2818048.2820065,Computer_Science_easy_419,"""We find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry,"" they say [pdf].","In particular, we find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry.","From a new batch of 15 models, the best algorithm selected six out of eight models that would shine on the runway. ""We find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry,"" they say [pdf]. A few shortcomings of the study exist, however.","Our framework successfully predicts most of the new popular models who appeared in 2015. In particular, we find that a strong social media presence may be more important than being under contract with a top agency, or than the aesthetic standards sought after by the industry. Accepted for presentation at CSCW '16 Modeling has in fact a very special meaning in fashion, a multi-billion dollar industry with strong social and economical implications worldwide .",[5],Computer_Science,train,5.0,news,http://www.techtimes.com/articles/81730/20150904/want-to-know-if-you-can-be-a-fashion-model-theres-a-machine-learning-algorithm-for-that.htm
10.1145/2661229.2661257,Computer_Science_easy_420,"This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices,"" the paper's abstract reads.",This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices.,"Moreover, those patterns can be formed into 3D shapes. This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices,"" the paper's abstract reads. This is what the team means when they say the haptics can be ""seen"".","This mid-air haptic feedback eliminates the need for any attachment of actuators or contact with physical devices. The user perceives a discernible haptic shape when the corresponding acoustic interference pattern is generated above a precisely controlled two-dimensional phased array of ultrasound transducers. This method is also possible with magnetic levitation, removing the need for the articulated arm .",[5],Computer_Science,train,5.0,news,http://www.cnet.com/news/ultrasound-creates-a-haptic-shape-that-can-be-seen-and-felt/
10.1038/srep16456,Computer_Science_easy_421,"When coupled with the fact that the underlying structure is unknown, unless dismantled atom-by-atom, this makes simulation extremely difficult.","When coupled with the fact that the underlying structure is unknown, unless dismantled atom-by-atom, this makes simulation extremely difficult.","Coupled with the fact that they can be incorporated into any material makes them an ideal candidate to replace existing authentication technologies. When coupled with the fact that the underlying structure is unknown, unless dismantled atom-by-atom, this makes simulation extremely difficult. ""While inhomogeneity in the fabrication of nanostructures often leads to unpredictable behaviour of the final device, which is normally undesirable, we have proposed and demonstrated a potential use for the quantum behaviour of atomically irreproducible systems.""","Simulating these structures requires vast computing power and is not achievable on a reasonable timescale, even with a modest quantum computer 18 . When coupled with the fact that the underlying structure is unknown, unless dismantled atom-by-atom, this makes simulation extremely difficult. Given the impracticality of copying the device at the atomic level, such technology would provide near guaranteed unclonability.",[5],Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2015/11/151113110108.htm
10.1038/s41528-018-0025-1,Computer_Science_easy_422,"The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision.","The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision.","""The appropriate packaging material also needs to comply with the soft elasticity of the hosting surface, minimizing any kind of discomfort caused when the tag is placed on the often soft asymmetric surface of marine animals, and supporting freedom of movement without any restrictions,"" she adds. The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision. ""We are working with the Red Sea Research Center at KAUST and external collaborators to further expand testing on a variety of animals such a dolphins and whale sharks,"" notes Hussain.","The geometrical ""net"" architecture along with the intrinsic stretchable properties of PDMS, allow the system to conform to the body of the animal and stretch/ contract with their movements, ensuring comfort and adhesion under any circumstance. The fabrication process is conducted using a low-cost CMOS compatible approach, allowing ease of scalability, batch fabrication, and precision. 2 , showing compliant 3D integration of the SoC on top of the sensory array ( Fig.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=33986546650&p=1pl&v=1&x=ofTcLrSSf2eizfly9znMUQ
10.1073/pnas.1322184111,Computer_Science_easy_423,Their findings suggest new therapeutic options for clinical populations that receive little benefit from conventional sensory rehabilitation strategies.,These findings suggest new therapeutic options for clinical populations that receive little benefit from conventional sensory rehabilitation strategies.,"Their findings will be published in PNAS Online Early Edition the week of June 9-13, 2014. Their findings suggest new therapeutic options for clinical populations that receive little benefit from conventional sensory rehabilitation strategies. ""Over the course of training, both species learned adaptive search strategies that allowed them to more efficiently convert noisy, dynamic audio cues into actionable information for finding the target.","By training humans and mice with an audio game inspired by sensory foraging behavior, we show that learning to discriminate simple, easily controlled sounds can generalize to improved neural and perceptual processing of ""real-world"" complex sounds, including speech in noise. These findings suggest new therapeutic options for clinical populations that receive little benefit from conventional sensory rehabilitation strategies. We found that, although both humans and mice learned to improve their foraging efficiency with practice, disparate behavioral strategies were used both within and across species.",[5],Computer_Science,train,5.0,news,http://www.sciencedaily.com/releases/2014/06/140609153427.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/scirobotics.aaq0899,Computer_Science_easy_424,"""If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers,"" the study authors write.","If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers.","The invention may allow scientists to grow tissue grafts used for transplantation, the study authors point out in their paper, referring to a separate study published in Science Robotics. Additionally, it may help with physical training. ""If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers,"" the study authors write.","An interesting application is active crash test dummies used during car crash testing, because current dummies can only measure passive behavior. If a humanoid can replicate human movements, then the resulting muscle contribution analysis or sensory data obtained during motion will benefit athletes or sports trainers. Similar link lengths and mass distributions (in other words, body proportions) to humans provide similar kinematics and dynamics.",[5],Computer_Science,train,5.0,news,http://ct.moreover.com/?a=32847326211&p=1pl&v=1&x=eAGjPeOZXzUdxGvzt4Ouqw
10.1186/s13174-018-0093-4,Computer_Science_easy_425,"The studied astrocytes, derived from Parkinson's disease patients with a genetic mutation that affects cell clean-up functions, caused more accumulation of the toxin, a -synuclein, than those derived from healthy individuals.",A little useful 23%,"The studied astrocytes, derived from Parkinson's disease patients with a genetic mutation that affects cell clean-up functions, caused more accumulation of the toxin, a -synuclein, than those derived from healthy individuals. The work, which appears January 10 in the journal Stem Cell Reports, suggests an important role for glial cells in Parkinson's disease and offers potential new targets for developing therapies. ""Our overall results completely turn our previous view of the participation of astrocytes in Parkinson's disease upside down.","When asked to what extent users feel freer in their ability to express themselves on Twitter and/or Facebook without concerns about surveillance or security of the messages sent when using SecurePost, most said they feel freer to some extent (73%). A little useful 23% Somewhat useful 41%",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38261605278&p=1pl&v=1&x=FA3eEIXpOyRcayGOMYfYPg
10.1126/scirobotics.aat0485,Computer_Science_easy_426,These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids.,"4, A and B, iii).","These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids. The gold body of the nanorobots responds to ultrasound, which gives them the ability to swim around rapidly without chemical fuel. This mobility helps the nanorobots efficiently mix with their targets (bacteria and toxins) in blood and speed up detoxification.","However, substantial lower hemolysis (5.5%) was observed when using US-propelled RBC-PL-robots in the toxin solution (Fig. 4, A and B, iii). These results confirmed the effective binding of the membranecoated robots to the toxin and indicated that the efficient US propulsion in the -toxin solution facilitated the number of robot-toxin contacts, improving the toxin absorption and its neutralization.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34185745506&p=1pl&v=1&x=sDZosR-98rK289RvFpVrSw
10.1016/j.neuroimage.2016.11.025,Computer_Science_easy_427,"Needless to say, I wasn't a big fan of Musk's quasi-lunch break.","In contrast, our results suggest that a different pattern of cortical organization may underlie reports of spontaneous mind-wandering: In particular, participants who reported higher rates of spontaneous mind-wandering tended to have cortical thinning in left angular gyrus within the DMN, extending to regions in the IPS implicated in executive control (Fig.","Loosely scheduling out my day and closing my inbox when it isn't time to check email are two things I'll take away from this experience. Because of the sheer amount of aforementioned pesto pasta I brought, it took me 10. Needless to say, I wasn't a big fan of Musk's quasi-lunch break.","The observation that higher deliberate mind-wandering was associated clusters in both the DMN and FPN suggests that the process of mind-wandering in a deliberate manner depends, in part, on the integration of the executive control and default mode networks as predicted by contemporary accounts of this experience (see . In contrast, our results suggest that a different pattern of cortical organization may underlie reports of spontaneous mind-wandering: In particular, participants who reported higher rates of spontaneous mind-wandering tended to have cortical thinning in left angular gyrus within the DMN, extending to regions in the IPS implicated in executive control (Fig. 4) .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33896004766&p=1pl&v=1&x=YNr544jvarWvao8REh4pcQ
10.1126/scirobotics.aar7555,Computer_Science_easy_428,"Practical Uses

Apart from being amusing to look at, the nature-inspired robots actually have practical implications in different fields such as in exploration and medicine.","In this case, x a /L approaches ±0.5, and anchoring occurs at the tail during inflation/elongation and at the head during deflation/shortening, completely preventing backward sliding.","Interestingly, the shape of the scales determined the speed of the robot wherein the trapezoidal pattern gave the robot a longer stride compared to the triangular, linear, and circular scales. This allowed the robots to expand and deflate and, with the help of its scales, move forward as long as it is attached to the air source. Practical Uses

Apart from being amusing to look at, the nature-inspired robots actually have practical implications in different fields such as in exploration and medicine.","By balancing the frictional forces exerted by the substrate on the skin (while neglecting inertial forces due to the slow nature of the crawling motion), we show that (see the Supplementary Materials for details) indicates that, to maximize the distance traveled by the crawlers, the ratio m b /m f should be as large as possible. In this case, x a /L approaches ±0.5, and anchoring occurs at the tail during inflation/elongation and at the head during deflation/shortening, completely preventing backward sliding. Moreover, Eq.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33380244548&p=1pl&v=1&x=WO8DjNm-VRsU2vah8HebhA
10.1038/nature13986,Computer_Science_easy_429,"""We noticed that, in the absence of the CTCF protein, the insulating boundaries of TAD domains had almost fully disappeared, so that genes and regulatory elements could now interact with those in adjacent TADs,"" Dr. Nora said.",Similar results were observed for additional examples (Extended Data Fig.,"The team demonstrated the importance of CTCF for the insulation of TADs. ""We noticed that, in the absence of the CTCF protein, the insulating boundaries of TAD domains had almost fully disappeared, so that genes and regulatory elements could now interact with those in adjacent TADs,"" Dr. Nora said. However, the absence of CTCF had little effect on how genes connect within a single TAD.","In this example, early replication appears to have spread into the late region up to a point that coincides with the nearest TAD boundary, where a new TTR was formed. Similar results were observed for additional examples (Extended Data Fig. Taken together, these results provide compelling evidence that TADs act as stable units of replication-timing regulation during development.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/u-SpIrhAW6Y/dna-human-cells-04879.html
10.1126/scirobotics.aat2516,Computer_Science_easy_430,"This new microphone-like system hears more like the way our own ears do, requiring little or no power, and could help fill the world with voice-responsive machines.",Further structure design can be applied to the inner film for frequency response modulation.,"This new microphone-like system hears more like the way our own ears do, requiring little or no power, and could help fill the world with voice-responsive machines. (If that's something we really want.) They're still trying to figure out why this happens, but what matters to engineers is that it happens reliably.","This work exhibits a prospective application of the TENG-based sensor for meeting the future challenges of robotics. Further structure design can be applied to the inner film for frequency response modulation. Because of the simple structure and the properties of selected materials in TENG technology, the device can be tiny, thin in size, and even transparent in appearance for wide applications (see photograph of the basic device in Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34636057541&p=1pl&v=1&x=WGgyRqxEwBjWORpgAKYA4Q
10.1038/nature18933,Computer_Science_easy_431,"He told the BBC the new map was ""a really big step forward"" and was built on an impressive variety of data.","The bilateral symmetry of functional organization is striking, in that nearly all areas have qualitatively very similar hues in the left and right hemispheres.","""It will now be the parcellation that is used by all of neuroscience, I would think."" He told the BBC the new map was ""a really big step forward"" and was built on an impressive variety of data. It betters the descriptions that have been available up till now,"" Prof Eickhoff said.","The remaining regions form a complex mosaic, with some intermixing of lighter (task-positive) and darker (task-negative) areas along with many lighter or darker pastel hues suggestive of 'cognitive' areas that may be preferentially associated with one or another sensory modality. The bilateral symmetry of functional organization is striking, in that nearly all areas have qualitatively very similar hues in the left and right hemispheres. However, interesting colour asymmetries occur in a few areas, especially language-related areas 55b, PSL, SFL, and 44 and their right hemisphere homologues, which also have asymmetric task-fMRI functional profiles (see Supplementary Neuroanatomical Results 8, 21 and 22) .",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/brain-map-carves-cortex-into-twice-as-many-areas/
10.1098/rspa.2012.0637,Computer_Science_easy_432,"However, it's not hard to imagine the Bristlebots demonstrating more intelligent-like behaviour by interacting together in more complex environments.","On the steepening gradient near the edge, the BBot typically slips backwards, as it rotates by about 30","At the moment, the BristleBot behaviour and the environment in which they are confined are both relatively simple. However, it's not hard to imagine the Bristlebots demonstrating more intelligent-like behaviour by interacting together in more complex environments. Termites do it so it's not beyond the realms of possibility that a swarm of Bristlebots in an appropriate environment could end up pushing sand or Lego bricks around ina way that forms a termite mound-like structure.","This pendulum-like effect follows from the fact that the walker's path is never perfectly radial, so that as a BBot climbs the edge it also turns sideways. On the steepening gradient near the edge, the BBot typically slips backwards, as it rotates by about 30 These oscillations may be repeated a few times for an individual Bbot before it eventually moves back into the center of the arena, and then onto another part of the edge where the same phenomena is repeated.",[1],Computer_Science,train,1.0,news,http://www.technologyreview.com/view/511881/toothbrushes-bristlebots-and-the-nature-of-intelligence?nopaging=1
10.1177/0018720813500305,Computer_Science_easy_433,Contestant Jason Zuffranieri Wins His 15th Game Jeopardy!,Performance improvement occurs in conditions of monotony as well as under conditions designed to cause fatigue.,"It ' s almost safer to some degree in those houses because they know what they're dealing with,"" she said , ""as opposed to other families who are still trying Some parents in Silicon Valley are embracing a more aggressive approach. Contestant Jason Zuffranieri Wins His 15th Game Jeopardy! 5 on the all-time highest regular season winnings list with the win.","Strategic secondary task performance has the effect of increasing alertness as measured by EEG, and improving driving performance, as measured by lane keeping. Performance improvement occurs in conditions of monotony as well as under conditions designed to cause fatigue. Sustained dual-tasking does not lead to the same improvement and also appears to incur costs.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=40228989984&p=1pl&v=1&x=TnkcB7nRmwX_rOjafPL9TQ
10.1111/j.1083-6101.2012.01584.x,Computer_Science_easy_434,"Segun los investigadores, cuando los roedores juegan entre ellas, algunas veces emiten un sonido distintivo que los cientificos relacionaron directamente con la risa.","Whilst the duration of the interaction for FTF positively predicted happiness, there was no effect of duration on happiness for the other modes, including those CMC modes that included auditory cues (Skype and telephone).","De hecho, se han documentado escenas de sonrisas en especies animales como los simios e incluso en ratas de laboratorio que mantuvieron esta interaccion en sus habitat. Segun los investigadores, cuando los roedores juegan entre ellas, algunas veces emiten un sonido distintivo que los cientificos relacionaron directamente con la risa. Es una senal, segun los investigadores, que emiten estos animales para indicar que estan jugando y no se estan peleando.","Hypothesis 1 was only partially supported. Whilst the duration of the interaction for FTF positively predicted happiness, there was no effect of duration on happiness for the other modes, including those CMC modes that included auditory cues (Skype and telephone). Results showed robust support for Hypothesis 2.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38502069878&p=1pl&v=1&x=wiU2fhsAX_no3fUpIz0CPw
10.1038/nature12311,Computer_Science_easy_435,"This will give them a better idea of what is being disrupted.""","Moreover, we can associate them with distinct functional roles in diverse types of post-transcriptional regulation, enabling new insights into the functions of RNA-binding proteins both in normal physiology and in human disease.","He anticipates that the team's compendium will be useful in human genetic analysis. This will give them a better idea of what is being disrupted."" ""We anticipate that this new knowledge will be valuable to other program members working on specific disorders.""","The motifs that we identify in vitro correlate well with in vivo RNA-binding data. Moreover, we can associate them with distinct functional roles in diverse types of post-transcriptional regulation, enabling new insights into the functions of RNA-binding proteins both in normal physiology and in human disease. These data provide an unprecedented overview of RNA-binding proteins and their targets, and constitute an invaluable resource for determining post-transcriptional regulatory mechanisms in eukaryotes.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130710141858.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41586-018-0361-2,Computer_Science_easy_436,"Even after reduction and compression, the data amassed in just one hour is similar to the data volume Facebook collects in an entire year - too much to store and analyze.","The Higgs-boson discovery analyses firmly established its interactions with the electroweak-force-carrying particles, namely the photon, W boson and Z boson.","Even after reduction and compression, the data amassed in just one hour is similar to the data volume Facebook collects in an entire year - too much to store and analyze. Luckily, particle physicists don't have to deal with all of that data all by themselves. ""Machine learning plays a role in almost all data aspects of the experiment, from triggers to the analysis of the remaining data,"" he says.","The increase in sensitivity due to the use of machine learning was equivalent to collecting 50% more data. The Higgs-boson discovery analyses firmly established its interactions with the electroweak-force-carrying particles, namely the photon, W boson and Z boson. This means that the Higgs boson is expected to decay into heavier quarks and leptons more often than into their lighter cousins.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34694267415&p=1pl&v=1&x=zuOQhiUaWUqOdn7M4JbnWg
10.1126/science.aao3466,Computer_Science_easy_437,"Why it matters: It's another sign, along with a commitment to build a ""more meaningful"" social network, that Facebook is responding to criticism about fake news, Russian meddling, and addictive content.","Here, any location with access to a sufficiently diverse market of chemical precursors and suitable cartridge fabrication facilities could be used to produce chemical products, which could previously be achieved only in a fully equipped synthesis laboratory with highly trained staff.","What it says: Of the thousands of words published in a pair of new essays on the topic, the choicest cut comes from Facebook's product manager for civic engagement, Samidh Chakrabarti:

If there's one fundamental truth about social media's impact on democracy it's that it amplifies human intent-- both good and bad.I wish I could guarantee that the positives are destined to outweigh the negatives, but I can't. Why it matters: It's another sign, along with a commitment to build a ""more meaningful"" social network, that Facebook is responding to criticism about fake news, Russian meddling, and addictive content.","The distribution model for fine and specialty chemicals, such as the APIs implied by this approach, would lead to a decentralizing of logistical approaches to chemical manufacture. Here, any location with access to a sufficiently diverse market of chemical precursors and suitable cartridge fabrication facilities could be used to produce chemical products, which could previously be achieved only in a fully equipped synthesis laboratory with highly trained staff. This approach not only holds promise for eventually delivering on-demand personalized medicines manufactured at, or near, the point of use, but also has short-term potential applications in the synthesis of APIs that are currently out of production.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33062363920&p=1pl&v=1&x=50fF7mZRqIZq3lCGiJHBBg
10.1016/j.jss.2015.04.065,Computer_Science_easy_438,They should also monitor any unusual network traffic that passes between the passenger cabin and the cockpit in order to watch out for any attempts at hacking.,"OpenRISA is integrated with the tool Decreasoner , and can check the correctness of the propositional formula such as this.","Monitoring the network

It is becoming imperative that airlines re-evaluate their internal aircraft security, particularly with the introduction of in-flight passenger Wi-Fi. They should also monitor any unusual network traffic that passes between the passenger cabin and the cockpit in order to watch out for any attempts at hacking. The same principles that enable the hacking could be used to watch out for them by allowing two independent monitors to observe the causes and effects of unfolding events on the network via satellite.","The three statements together therefore say that, S1, S2, S1 ∧ S2 → S3. OpenRISA is integrated with the tool Decreasoner , and can check the correctness of the propositional formula such as this. As shown in Fig.",[1],Computer_Science,train,1.0,news,http://www.homelandsecuritynewswire.com/dr20150521-how-a-hacker-could-hijack-a-plane-from-their-seat
10.1038/s42003-019-0305-x,Computer_Science_easy_439,"The researchers say without the test, they would have never known whether those drugs worked on that specific cancer.",Use of a robotic system or automated 96-well pipettor is theoretically feasible as long as temperature and plate positioning can be effectively controlled.,"The organoid grown from her cancer cell showed a positive response from a drug class known as cyclin-kinase inhibitors. The researchers say without the test, they would have never known whether those drugs worked on that specific cancer. ""This could become a powerful tool to help guide therapies for people who really have no known treatment options left,"" Soragni said.",Rings can be established using a single-well or multichannel pipette. Use of a robotic system or automated 96-well pipettor is theoretically feasible as long as temperature and plate positioning can be effectively controlled. The combination of small volume plated (10 µl) and surface tension holds the cells in place until the Matrigel solidifies upon incubation at 37°C and prevents two-dimensional (2D) growth at the center of the wells.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38645280193&p=1pl&v=1&x=NvwrTNIPdlqltjweHE53CA
10.1145/3205455.3205541,Computer_Science_easy_440,"""The legs are readily convertible into 3-D-printable files, so we can easily print the legs and clip them onto our hexapods for deployment,"" Howard said.","Despite this, mean times for a full experiment set (10 repeats in an environment) are 7 hours, 2.7 days, and 9.4 days respectively.","This research demonstrates a design algorithm that can automatically generate 3-D printable components so that our robots are better equipped to function in different environments."" ""The legs are readily convertible into 3-D-printable files, so we can easily print the legs and clip them onto our hexapods for deployment,"" Howard said. This approach allows the algorithm to search for good shapes to apply on the robot's legs, within a space of possible solutions.","Importantly, native support is provided to distribute the simulation effort in parallel across high-performance computing nodes; (i) each experimental repeat is run in parallel (ii) all evaluations in a generation are conducted in parallel, and (iii) each individual particle-based evaluation distributes across a compute node. Despite this, mean times for a full experiment set (10 repeats in an environment) are 7 hours, 2.7 days, and 9.4 days respectively. Hexapod bodies do not directly interact with the environment, allowing us to optimise legs only.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37505835776&p=1pl&v=1&x=ByicUH1dO77Je1pIjb2Upw
10.1016/j.gpb.2015.01.009,Computer_Science_easy_441,"At the end of the day, not everything that's done in the name of nano is special, unique, or interesting.","However, the error rates of these analyses were over 90% .","And because of this, it's not necessarily a bad thing that, once in a while, its underlying nano-assumptions are challenged. At the end of the day, not everything that's done in the name of nano is special, unique, or interesting. And scientifically, there's nothing particularly special about that bright line between the worlds below and above 100 nanometres.","This is much longer than the average read lengths of other DNA sequencing technologies, which are hundreds of base pairs. However, the error rates of these analyses were over 90% . Although the MinION is still a long way from use in a wide range of applications, these results are very encouraging for nanopore-based DNA sequencing technology.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34177756696&p=1pl&v=1&x=rGd00IhvP7YttqFDWWGEQQ
10.1038/s41598-018-38303-x,Computer_Science_easy_442,"""We show for the first time a physical understanding of the security properties of human body communication to enable a covert body area network, so that no one can snoop important information,"" Sen said.","For both capacitive as well as galvanic coupling, the potential difference created by the magnetic fields is ignored since no closed coupling loops exist at the transmitting or Oscilloscope with the transmitter wearable device on the device arm.","The technology would also help streamline the advent of closed-loop bioelectronic medicine - in which wearable or implantable medical devices function as drugs, but without the side effects - and high-speed brain imaging for neuroscience applications. ""We show for the first time a physical understanding of the security properties of human body communication to enable a covert body area network, so that no one can snoop important information,"" Sen said. Enabling Covert Body Area Network using Electro-Quasistatic Human Body Communication,(2019).","This work presents various experiments in both time and frequency domains using custom-designed EQS-HBC device, supported by theoretical leakage models to analyze this side-channel QS leakage, and demonstrates the privacy and security of human body data transmission using EQS-HBC. For both capacitive as well as galvanic coupling, the potential difference created by the magnetic fields is ignored since no closed coupling loops exist at the transmitting or Oscilloscope with the transmitter wearable device on the device arm. The measured QS leakage from the device hand is dominated by the leakage due to the EQS-HBC transmitter, while the free hand leakage corresponds to QS leakage due to the human body (HB) alone.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38746293538&p=1pl&v=1&x=KW3S_6SReyayoHHcnN7n6Q
10.1126/science.aaj2038,Computer_Science_easy_443,The process was successful with no errors occurring.,DNA is an attractive medium to store digital information.,The process was successful with no errors occurring. They also said that this technique can create unlimited copies by multiplying the DNA samples using the polymerase chain reaction. What's more amazing is that the copies are error-free as well.,"DNA is an attractive medium to store digital information. Finally, we explored the limit of our architecture in terms of bytes per molecule and obtained a perfect retrieval from a density of 215 petabytes per gram of DNA, orders of magnitude higher than previous reports. DNA is an excellent medium for data storage, owing to its demonstrated information density of petabytes of data per gram, high durability, and evolutionarily optimized machinery to faithfully replicate this information (1, 2).",[1],Computer_Science,train,1.0,news,http://www.universityherald.com/articles/68363/20170308/digital-files-in-your-dna.htm
10.1038/s41467-018-05378-z,Computer_Science_easy_444,"But taken together, I'm probably the only triple shot, iced vanilla latte-drinking, table-cleaning, glasses-tipping person in Seattle.",The identity of the nt post-mutation was one of the three nts not present at that position pre-mutation.,"None of these quirks is particularly unique. But taken together, I'm probably the only triple shot, iced vanilla latte-drinking, table-cleaning, glasses-tipping person in Seattle. If I ever committed a crime and the police were out to get me, this combination of quirks may be just enough to identify me.","The alignment of the entire pCI-YFP plasmid to the Addgene training set returned >10 4 matches. We found the smallest non-zero E-value (4 × 10 −180 ) and then counted the number of alignments with an E-value of zero to conclude that 11,369 plasmid alignments have an E-value < 10 −180 . The identity of the nt post-mutation was one of the three nts not present at that position pre-mutation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34762351148&p=1pl&v=1&x=Gd75QlQBxa5p4k1G77uc_Q
10.1038/nature20607,Computer_Science_easy_445,"As reported online in Nature on Nov. 30, the research is a step toward a nature-inspired means for delivering therapeutics directly to specific cell types within the body.","By contrast, cells that expressed the control I3-01-Myc construct released very little VSV-G and no BlaM-Vpr, indicating that these two proteins were probably released via EPN incorporation.","As reported online in Nature on Nov. 30, the research is a step toward a nature-inspired means for delivering therapeutics directly to specific cell types within the body. Adding on specific pieces of genetic code from viruses caused the nanocages to be packaged within cell membranes, and then exported from cells. ""We are now able to accurately and consistently design new proteins with tailor-made structures,"" says King.","EPN-01*, BlaM-Vpr and VSV-G were efficiently released together from 293T producer cells as designed (Fig. By contrast, cells that expressed the control I3-01-Myc construct released very little VSV-G and no BlaM-Vpr, indicating that these two proteins were probably released via EPN incorporation. Consistent with this interpretation, the fraction of EPN-01* assemblies with visible surface spikes increased fourfold upon VSV-G pseudotyping (Fig.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/GrPqFG55fAA/
10.1126/scirobotics.aal2505,Computer_Science_easy_447,"Along with using thin elastic wings, this allowed them to make a more lightweight and flexible Bat Bot, instead of other bat-inspired drones that tend to be too bulky to fly smoothly.",7.,"(Photo : Ian Waldie/Getty Images)

This seems like something out of Bruce Wayne's arsenal: a compact drone that looks, glides and flies like an actual bat. Along with using thin elastic wings, this allowed them to make a more lightweight and flexible Bat Bot, instead of other bat-inspired drones that tend to be too bulky to fly smoothly. That gives us extra flight time.""","The stability of the designed periodic solutions can be checked by inspecting the eigenvalues of the monodromy matrix [Eq. 7. As a result, classical feedback design tools can be applied to stabilize the system.",[1],Computer_Science,train,1.0,news,http://www.natureworldnews.com/articles/35382/20170202/new-bat-bot-mimics-bats-sophisticated-flight-mechanics.htm
10.1145/3230833.3232807,Computer_Science_easy_448,"""I guess you could say it was love at first sight,"" he says.","Pepper offers to users a nice web page where some administrative tasks, such as factory reset and password change, can be easily performed.","Pepper can answer simple questions that customers would have asked workers behind the counter. ""I guess you could say it was love at first sight,"" he says. The robot understood his Australian accent and he thought of other Americans who deal with language barriers while shopping and banking.","After a quick verification of the CPU model, we report that Pepper is prone both to Meltdown and Spectre attacks . Pepper offers to users a nice web page where some administrative tasks, such as factory reset and password change, can be easily performed. As soon as we opened the web page, we noticed that the communication is established over HTTP, rather than HTTPS.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39409174721&p=1pl&v=1&x=1r7w8GxSU80ErqLP7ereOw
10.1073/pnas.1801181115,Computer_Science_easy_449,But Zhang thinks the test is flawed because it is subjective.,and S.L.,"Zhang says the research, which will appear in the Proceedings of the National Academy of Sciences, is an important first step toward a more ambitious goal of his, which is designing a replacement to the Turing test--the current gold standard for gauging machine intelligence. But Zhang thinks the test is flawed because it is subjective. ""That's very difficult to do, and not a particularly good use of programmers' time.""",and S.-C.Z. and S.L. All authors commented on the manuscript.,[1],Computer_Science,train,1.0,news,https://www.futurity.org/artificial-intelligence-periodic-table-1795132/
10.1073/pnas.1522419113,Computer_Science_easy_450,"Scientists can study tracking behavior in the laboratory using specially designed, artificial flowers constructed with their own small nectar pods.",[2],"The findings, published in the Proceedings of the National Academy of Sciences, illustrate the computational basis of this integration, which may serve as a general model for insects and other animals, including humans. Scientists can study tracking behavior in the laboratory using specially designed, artificial flowers constructed with their own small nectar pods. Hawkmoths respond to these pre-packaged dinners similarly to real flowers, and--if researchers manipulate the artificial flower to move when a hawkmoth is feeding--the hawkmoth adjusts its position to keep up.","Also, for the sensory conflict paradigms, the transfer function for the M-and V-only responses is [2] Note that, in conflict conditions, both sensory transforms, S v and S m , appear in the denominator; the denominator reflects the reafferent pathway, the negative feedback that represents ego motion with respect to both the moving and stationary features.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/hawkmoths-vision-touch-senses-1294212-2/
10.1145/3290350,Computer_Science_easy_451,"First, the tool synthesizes probabilistic programs that represent Bayesian models for data, whereas traditional methods produce programs that do not model data at all.",while Lik E 0 (X ) = 0 5:,"The approach is different from ordinary program synthesis in two ways. First, the tool synthesizes probabilistic programs that represent Bayesian models for data, whereas traditional methods produce programs that do not model data at all. Users can pick and choose which models best fit their application.",Sections 5 and 6 show two concrete examples of how DSL programs can be translated into Venture programs and how to use inference programming in Venture to obtain predictions on new data. while Lik E 0 (X ) = 0 5: return E n Using MCMC for synthesis allows us to rigorously characterize soundness conditions.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38256121332&p=1pl&v=1&x=dhdbwfWKWkGwrSGRJIg7Kg
10.1007/s00181-014-0833-7,Computer_Science_easy_452,"""This should give decision-makers some important information as they allocate funding.""","For Physics, the p-value is 0.0463, and so convexity is just rejected at the 5-percent level, but not at the 1-percent level.","Eileen Kraemer, the C. Tycho Howle Director of the School of Computing, said that the research highlights Clemson's strengths in data-enabled science and high-performance computing. ""The research provides statistical evidence and some quantification,"" she said. ""This should give decision-makers some important information as they allocate funding.""","We clearly fail to reject the null hypothesis of convexity for Chemistry, Civil and Environmental Engineering, Computer Science, Ecology and Evolutionary Biology, and Economics, with p-values greater than 0.72 in each case. For Physics, the p-value is 0.0463, and so convexity is just rejected at the 5-percent level, but not at the 1-percent level. By contrast, for English and History, convexity is soundly and clearly rejected, with p-values well below 0.01.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150323182923.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41598-017-03412-6,Computer_Science_easy_453,",,Dreimal ist okay"", sagt Paulino, danach werden die Streben mude und vergessen ihre Erinnerung - auch hier braucht es noch Forschungsarbeit.",Such a design leads to successful deployment (Movie S3).,"Praktisch gehen sie zur Zeit nach mehrmaligem Benutzen kaputt. ,,Dreimal ist okay"", sagt Paulino, danach werden die Streben mude und vergessen ihre Erinnerung - auch hier braucht es noch Forschungsarbeit. Die grosste Herausforderung fur die Forscher besteht aber derzeit darin, die Massstabe der 4D-Strukturen zu verandern, sie kleiner und grosser zu machen.","In this way, the tensegrity deployment becomes more deterministic, while the structure can still be stored in a compact state that occupies much less space than its deployed configuration. Such a design leads to successful deployment (Movie S3). Our active tensegrity can be used to form 3D structures with surfaces that can serve as a platform to host functional devices.",[1],Computer_Science,train,1.0,news,https://www.wired.de/collection/science/4d-figuren-3d-drucker-weltraum-forschung
10.1287/mnsc.2013.1784,Computer_Science_easy_454,"Unless you did CrossFit all week and possess a super-jacked, revved up metabolism and high level of fitness, your couch-sitting marathons will slowly kill you--from heart disease .",This effect could also be driven by the fact that busier individuals are more in need of a reason to visit the gym.,"), binging on seasons three and four of Game of Thrones (plus bonus footage) and the season five leak, will probably result in weight gain. Unless you did CrossFit all week and possess a super-jacked, revved up metabolism and high level of fitness, your couch-sitting marathons will slowly kill you--from heart disease . So consider temptation bundling.","This finding is consistent with the prediction that temptation bundling may be most powerful when it both increases the attractiveness of exercise and reduces guilt that can be associated with engaging in indulgent behaviors, as busier individuals are most likely to regret spending time on wants. This effect could also be driven by the fact that busier individuals are more in need of a reason to visit the gym. Sixty-four percent of participants indicated that this program ""sound[ed] appealing"" to them when asked on a ""yes/no"" scale (t(211) = 19.43; p < 0.0001), demonstrating that temptation bundling devices are valued and adding to the mounting evidence of demand for commitment devices .",[1],Computer_Science,train,1.0,news,http://www.thedailybeast.com/articles/2015/04/19/how-would-tyrion-lannister-work-out.html
10.1016/j.jag.2015.03.017,Computer_Science_easy_455,"(U.S. Department of Agriculture, CC BY 2.0)

Compared to older, conventional furrow and flood application technologies, center pivot and other sprinkler methodologies and drip irrigation systems improve the uniformity of water application, reducing the amount of water lost to deeper percolation or runoff from the field.","(10) and (11), respectively:","It makes it easier to limit the amount of water that seeps beneath where the roots of the crop can reach. (U.S. Department of Agriculture, CC BY 2.0)

Compared to older, conventional furrow and flood application technologies, center pivot and other sprinkler methodologies and drip irrigation systems improve the uniformity of water application, reducing the amount of water lost to deeper percolation or runoff from the field. And they don't necessarily result in significant improvements in overall efficiency, since they don't address the losses that happen during storage, transmission, and distribution of irrigation water.","The larger the value of E and the smaller the value of RMSE, the greater the precision and accuracy of the model to predict chlorophyll. (10) and (11), respectively: After numerous computational runs, four options presented themselves as potential ""best model"" scenarios (Table 4 ).",[1],Computer_Science,train,1.0,news,http://www.theepochtimes.com/n3/1372733-technologies-will-tackle-irrigation-inefficiencies-in-agricultures-drier-future/
10.1073/pnas.1721286115,Computer_Science_easy_456,"Such prediction of this dynamic topology was not previously possible, the researchers said.","Such large nonisochronicity is an important oscillatory property, which was computationally predicted by a biomolecular model of the SCN and supported in Fig.","When they applied Li's algorithm to the network of interactions among the synthetic oscillators, the results matched what Kiss had determined through his experiments, finding the same connections in a network of 15 chemical oscillators. Such prediction of this dynamic topology was not previously possible, the researchers said. Li said this method has a variety of applications beyond cell networks.","We note that the averaged interaction functions often have large cosine harmonics, which results in nearly zero slope at zero phase difference. Such large nonisochronicity is an important oscillatory property, which was computationally predicted by a biomolecular model of the SCN and supported in Fig. The network estimations using ICON differed depending on the synchronization behavior of the seven recorded quintets of mice (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34930725154&p=1pl&v=1&x=jYr2S2cmS45dqhbHsu5FrQ
10.1126/scirobotics.aat8829,Computer_Science_easy_457,"Several recognized experts with proven track records will effectively present the theories behind our strategies in a compelling way, and translate our keen insights into actionable stock recommendations for any market environment.","After coating the glass surface with Ti, the cells exhibited good morphology and proliferated.","Best wishes,

Jon D. Markman

P.S. Several recognized experts with proven track records will effectively present the theories behind our strategies in a compelling way, and translate our keen insights into actionable stock recommendations for any market environment. DISCLOSURE: The views and opinions expressed in this article are those of the authors, and do not represent the views of equities.com.","The microrobot exhibited the best cellloading capability when l b = r c . After coating the glass surface with Ti, the cells exhibited good morphology and proliferated. The survival rates of two types of cells on days 1, 3, and 5 are illustrated in Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34529082841&p=1pl&v=1&x=Z2oXwqLNP2LXgUk7j0nGOg
10.1073/pnas.1821740116,Computer_Science_easy_459,"Applications in diagnostics and treatment



A cell computer could be used to detect biological signals in the body, such as certain metabolic products or chemical messengers, process them and respond to them accordingly.","For a single reporter gene controlled by a gRNA, we observed dosedependent repression (SI Appendix, Fig.","This biological computer is not only extremely small, but in theory can be scaled up to any conceivable size. Applications in diagnostics and treatment



A cell computer could be used to detect biological signals in the body, such as certain metabolic products or chemical messengers, process them and respond to them accordingly. With a properly programmed CPU, the cells could interpret two different biomarkers as input signals.","1 observed correct circuit performance after 24 h, although the performance was improved after 48 h (SI Appendix, Fig. For a single reporter gene controlled by a gRNA, we observed dosedependent repression (SI Appendix, Fig. Addition of auxin shut off the circuit within 4 h, while removal of auxin from the medium restored the circuit function (SI Appendix, Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39022709468&p=1pl&v=1&x=wApqEkWGW0BictyzY4Ib_w
10.1080/10586458.2016.1270858,Computer_Science_easy_460,"""Having something you can move around with your hands can really help your intuition.""",Our calculation works directly in the continuum regime and does not require taking a limit from the discrete variant of the problem.,"""I'm excited by how 3D technology can be used in math,"" says Romik, who has a 3D printer at home. ""Having something you can move around with your hands can really help your intuition."" As Romik tinkered with translating Gerver's equations into something a 3D printer can understand, he became engrossed in the mathematics underlying Gerver's solution.","Moreover, in Case 1 we have additionally that A (t) = 0 (that is, the contact point A remains fixed during an interval when Case 1 is applicable), and similarly in Case 5 we have that C (t) = 0. Our calculation works directly in the continuum regime and does not require taking a limit from the discrete variant of the problem. 3.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/moving-sofa-problem-1383142-2/
10.1073/pnas.1313895111,Computer_Science_easy_461,"The best-seller list did have a 'mild' effect on the behaviour of Facebook users, but an instinct to copy the behaviour of others was by far the more dominant instinct.","In the SI, we show that this situation is described by a near-critical branching process, for which the mean-field asymptotic popularity distribution is the power law P (n) ∼ n −α , where α ∈ [3/2, 2) .","The researchers found that, although users seem to be influenced by both, the stronger effect on popularity dynamics was caused by the recent behaviour of others. The best-seller list did have a 'mild' effect on the behaviour of Facebook users, but an instinct to copy the behaviour of others was by far the more dominant instinct. Here, we found that the ""copycat"" tendency plays a very important role in online behaviour.","Even if all apps initially have the same number of installations, random fluctuations lead to some apps becoming more popular than others, and the aggregate popularity distribution becomes heavy-tailed . In the SI, we show that this situation is described by a near-critical branching process, for which the mean-field asymptotic popularity distribution is the power law P (n) ∼ n −α , where α ∈ [3/2, 2) . Our model suggests that app adoption among Facebook users was guided more by recent popularity of apps (as reflected in installations by friends within 2 days) than by cumulative popularity.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/07/140707152416.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.neuron.2018.02.031,Computer_Science_easy_464,"For further information, please contact the cited source.","Improved propagation is accompanied by a small change in gamma power across areas ( Figure 4B ), stemming from the stronger lateral inhibition associated with improved GBA.","Notably, the global activation pattern resembles the ones previously found in the human brain while consciously perceiving sensory information--a parallel suggesting a potential connection between the proposed ""balanced"" large-scale neural circuit mechanism for signal transmission and understanding how conscious information processing is achieved. Note: material may have been edited for length and content. For further information, please contact the cited source.","Increasing GBA improves signal transmission in this model as well ( Figure 4B ), suggesting that our mechanism is also valid for models equipped with more detailed laminar-specific projection patterns (Mejias et al., 2016) . Improved propagation is accompanied by a small change in gamma power across areas ( Figure 4B ), stemming from the stronger lateral inhibition associated with improved GBA. The moderate gamma power is in good agreement with experimental observations, which show the presence of a weakly coherent gamma rhythm during cortical interactions and its importance in local and long-distance interactions (Kopell et al., 2000; .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33639897854&p=1pl&v=1&x=Mf1vNLgAICgkKnF5WWY3pQ
10.1038/s41528-018-0040-2,Computer_Science_easy_467,"The only limits from now are really within our own imagination.""",SLG and FLG with different ranges of conductivity and transparency) to LEG.,"Dr Elias Torres Alonso, Research Scientist at Graphenea and former PhD student in Professor Craciun's team at Exeter added ""This new research opens up the gateway for smart textiles to play a pivotal role in so many fields in the not-too-distant future. The only limits from now are really within our own imagination."" It is very flexible and is one of the strongest known materials.","Furthermore, by using different types of graphene we demonstrate that our devices can be produced in a more industrial manufacturing compatible way. SLG and FLG with different ranges of conductivity and transparency) to LEG. S4a ), confirming the presence of the different types of graphene on the surface of the PP textile fibres.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37872718721&p=1pl&v=1&x=0iq7KeXC3HlVmVtDpTfy_w
10.1016/j.jctb.2019.01.007,Computer_Science_easy_468,All three enjoy working together.,"It remains to show that the right-hand side of (14) is at most , which would follow if for every (u, v) ∈ E 2 ,","""Most graduate students don't have as many papers."" All three enjoy working together. ""This leads to always feeling as if there is something else to try on a problem we are working on.""","On the other hand, the left-hand side of (12) may be written as (recall that all edges in E 1 have w as an endpoint) It remains to show that the right-hand side of (14) is at most , which would follow if for every (u, v) ∈ E 2 , Suppose equality occurs in Theorem 1.6.",[1],Computer_Science,train,1.0,news,http://news.mit.edu/2019/mit-undergraduates-solve-combinatorics-problem-0225
10.1371/journal.pcbi.1005824,Computer_Science_easy_469,"""The next step in our study is to use this type of big data approach to understand the difference in behavior between urban and rural populations, as it pertains to the role of social and biological clocks in their daily routines,"" Monsivais said in a journal news release.","Thus, if we measure the amount of time one distribution should be shifted in order to minimize its divergence from the second distribution.","And sleep times were longest in adolescence, young adulthood and the senior years, while shortest in middle age. Reporting Nov. 21 in PLoS Computational Biology, the study authors believe their findings could be useful to how modern societies plan for the health, economic, and public transportation needs of people. ""The next step in our study is to use this type of big data approach to understand the difference in behavior between urban and rural populations, as it pertains to the role of social and biological clocks in their daily routines,"" Monsivais said in a journal news release.","Applying Kullback-Leibler divergence to a pair of these distributions, it would reach a minimum value when these distributions overlap most, falling on top of each other and collapse to one. Thus, if we measure the amount of time one distribution should be shifted in order to minimize its divergence from the second distribution. • 0 ′ N, respectively.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32586931835&p=1pl&v=1&x=Ws58rIofqMXNELKK1CPLNQ
10.1126/science.aao0098,Computer_Science_easy_471,"The work, reported May 31 in Science, is a step toward creating artificial skin for prosthetic limbs, to restore sensation to amputees and, perhaps, one day give robots some type of reflex capability.","3G) , the highest pressure will have a dominant effect on the output of the ring oscillator.","The work, reported May 31 in Science, is a step toward creating artificial skin for prosthetic limbs, to restore sensation to amputees and, perhaps, one day give robots some type of reflex capability. ""This artificial sensory nerve system is a step toward making skin-like sensory neural networks for all sorts of applications."" Building blocks

This milestone is part of Bao's quest to mimic how skin can stretch, repair itself and, most remarkably, act like a smart sensory network that knows not only how to transmit pleasant sensations to the brain, but also when to order the muscles to react reflexively to make prompt decisions.","In the Fourier transform of each case (Fig. 3G) , the highest pressure will have a dominant effect on the output of the ring oscillator. When the object moved in the directions of the red and blue arrows, the postsynaptic current outputs had one valley corresponding to the object position between the two pressure sensors (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34191593323&p=1pl&v=1&x=yJT1Q5VVIqV9X_u8UhglUA
10.1038/s42256-019-0029-0,Computer_Science_easy_475,"""However, if you let these [new] robots learn from relevant experience, then they will eventually find a solution that, once found, will be put to use and adapted as needed.",We detect no right-to-left trend indicating that energy consumption was spontaneously reduced as performance improved.,"Marjaninejad also added this is particularly important because programmers can predict and code for multiple scenarios, but not for every possible scenario--thus pre-programmed robots are inevitably prone to failure. ""However, if you let these [new] robots learn from relevant experience, then they will eventually find a solution that, once found, will be put to use and adapted as needed. The solution may not be perfect, but will be adopted if it is good enough for the situation.","These movements can, in principle, propel the treadmill. We detect no right-to-left trend indicating that energy consumption was spontaneously reduced as performance improved. Conversely, higher reward did not always require higher energy consumption even though more external work was being done to propel the treadmill the furthest.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38737508190&p=1pl&v=1&x=n3hZRcXgEEchkc5JLTS2iQ
10.1093/bioinformatics/btu618,Computer_Science_easy_476,Each subtype can be identified by the unique pattern of the products produced by their genes.,"The median estimate is close to the true value of 0.5, and the spread of the estimates is small.",A drug that can target one subtype of cancer cells may have no effect on another subtype. Each subtype can be identified by the unique pattern of the products produced by their genes. The model identified the correct fractions of the two subtypes.,"The bottom panel of Figure 2 shows that GLAD is accurate across a wide range of sample sizes for mixed samples. The median estimate is close to the true value of 0.5, and the spread of the estimates is small. In contrast, LPD has a large variance across a range of sample sizes, and it appears to exhibit some bias, which does not disappear even at N = 6000.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141211115656.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1287/mnsc.2014.2030,Computer_Science_easy_477,"""Going out to dinner, that's a special treat,"" Riggs said.",The qualitative results do not change in any specification.,"Not everyone will likely feel comfortable swapping chatter with a server for paying using a robot. ""Going out to dinner, that's a special treat,"" Riggs said. ""For some older people or single people, that may be their social interaction, even if it's just with a server or a bartender.""","Second, it might be possible to exploit the matched pairs to increase power addresses these concerns by using flexible specifications for the functional form of the time series and by aggregating the fixed e↵ects to the pair level. The qualitative results do not change in any specification. Figure 4 repeats the analysis in Column (1) at a finer level of temporal detail.",[1],Computer_Science,train,1.0,news,http://www.marketwatch.com/news/story.asp?guid=%7B0DDB56DE-22A0-11E6-A5CC-DEDBBDD44BF7%7D&siteid=rss&rss=1
10.1145/2832905,Computer_Science_easy_478,And the results look impressive.,"The outermost should be traversed last, which are next to V ∂ (s + 1).","Nevertheless, Brunto and co have made significant advances by bringing to bear the many decades of research that has been done on color management for 2-D printing and for color imaging in general. And the results look impressive. In the pictures above, three apples and the thumb are real.","If we consider two surface voxels within the same connected component in slice s, the innermost should be traversed first, since they are next to V ∂ (s − 1) and have already received error diffused from slice s − 1. The outermost should be traversed last, which are next to V ∂ (s + 1). The situation is reversed for upward facing surfaces.",[1],Computer_Science,train,1.0,news,http://www.technologyreview.com/view/538676/solving-the-last-great-3-d-printing-challenge-printing-in-color/
10.1073/pnas.1309300110,Computer_Science_easy_479,"""One exciting implication of this work is that we might be held back in making more agile machines by our assumption that it's wasteful or useless to have forces in directions other than the one we are trying to move in.","That is, the nodal point controller, compared with the unidirectional wave controller, renders the system increasingly more maneuverable as movement amplitude decreases, confirming our hypothesis (Fig.","""We are far from duplicating the agility of animals with our most advanced robots,"" MacIver said. ""One exciting implication of this work is that we might be held back in making more agile machines by our assumption that it's wasteful or useless to have forces in directions other than the one we are trying to move in. It turns out to be key to improved agility and stability.""","5 A-II and B-II and Movie S2), but the ratio of the rms of the control signals, f rms : ΔL rms , increased dramatically as the amplitude of movement decreased (Fig. That is, the nodal point controller, compared with the unidirectional wave controller, renders the system increasingly more maneuverable as movement amplitude decreases, confirming our hypothesis (Fig. 5C , reveal the same trend observed in biomimetic robot experiments.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/11/131104152556.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41551-017-0178-6,Computer_Science_easy_480,"It's a significant commitment -- in mid-2017, Microsoft cut thousands of jobs as part of its shift to cloud services.","To actually rank gRNAs, one may want to summarize the scores from all gRNA-target pairs for a given gRNA into a single number so that gRNAs can be ranked by this number for off-target activity.","It's a significant commitment -- in mid-2017, Microsoft cut thousands of jobs as part of its shift to cloud services. The report highlighted the implications of broadband access for a range of industries, including healthcare, and discussed the role internet-assisted telemedicine may play in addressing physician shortages in rural areas.","Elevation-score provides only the starting ingredients for choosing a gRNA with the least expected off-target activity. To actually rank gRNAs, one may want to summarize the scores from all gRNA-target pairs for a given gRNA into a single number so that gRNAs can be ranked by this number for off-target activity. For Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34460216352&p=1pl&v=1&x=HZj81NOIqulbpM5XvQESSw
10.1177/0018720812450587,Computer_Science_easy_481,"Though none of his bosses wanted to improve the offensive tone, Reekes was so obsessed that he snuck into the office in the middle of the night to change it.",Spearcons averaged 0.28 s (range = 0.14-0.46 s).,"The original Mac startup noise, he said, was ""literally the most dissonant sound you can make""--a tritone chord also known as ""the devil's interval."" Though none of his bosses wanted to improve the offensive tone, Reekes was so obsessed that he snuck into the office in the middle of the night to change it. I was so sensitive to microseconds at the end of this that it really broke a logjam in my own work.","Therefore, spearcons are not simply ""fast talking"" menu items; they are distinct and unique sounds, albeit acoustically related to the original speech item. Spearcons averaged 0.28 s (range = 0.14-0.46 s). This was similar to the approach by .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32918689985&p=1pl&v=1&x=9f0CZrwEdSGNIaOa2NkIWg
10.1038/nature13162,Computer_Science_easy_482,"So, there you have it -- the signals from your nose translate and connect to memories in an orchestrated symphony of signals in your head.","Some increase was observed at , [] [] Hz, but a 20-Hz cut-off was used to avoid confounds with theta harmonics (,14-18 Hz; Fig.","Together, the evidence is now piling up and pointing in the direction of cortical oscillations as a general mechanism for mediating interactions among functionally specialized neurons in distributed brain circuits."" So, there you have it -- the signals from your nose translate and connect to memories in an orchestrated symphony of signals in your head. So when you feel a wave of reminiscence triggered by a fragrance, think about how waves created this connection in the first place.","The activity change was strongest in the 20-40-Hz frequency range, below the gamma-band frequencies that dominate running behaviour and in agreement with previous observations in olfaction-based discrimination tasks . Some increase was observed at , [] [] Hz, but a 20-Hz cut-off was used to avoid confounds with theta harmonics (,14-18 Hz; Fig. The power of the 20-40-Hz oscillation increased gradually during the cue sampling interval, peaked during the second half, and dropped back as soon as the animal left the port (Fig.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140416133341.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1461444814554900,Computer_Science_easy_483,But Ello and Diaspora aren't the only ones.,"These lenses, I should stress, are not free-floating concepts that I will simply grab from a theoretician and then ""apply"" to the DWSN.","But Ello and Diaspora aren't the only ones. ""GNU social works quite a bit like Twitter, but anyone can install it on their own servers. You can inspect the code, modify it how you like - there are so many more possibilities than with Twitter,"" added Gehl.","More to the point, it would be impossible to observe or speak with thousands of people. These lenses, I should stress, are not free-floating concepts that I will simply grab from a theoretician and then ""apply"" to the DWSN. These lenses come from the context in which the DWSN emerges: the ""media ideology"" of the dark web, specifically as this ideology appears in journalistic coverage.",[1],Computer_Science,train,1.0,news,http://www.newswise.com/articles/beyond-facebook-the-social-media-alternatives-project
10.1007/s10916-017-0778-4,Computer_Science_easy_484,What actually happened was that competing companies deliberately created incompatible systems.,"This processed reduced the final group for analysis to 25 (7 from PubMed, 7 from CINAHL, 11 from ProQuest).","Crucially, rather than forcing competing systems to be compatible in order to receive federal support, the administration believed the market would decide on a standard to communicate. What actually happened was that competing companies deliberately created incompatible systems. For many medical professionals, particularly independent physicians, faxing is far easier than dealing with expensive, hard-to-use software that doesn't actually do what it was supposed to: securely share patient information.","This reduced the number of articles to 133 (41 Pubmed, 34 CINAHL, 58 ProQuest). This processed reduced the final group for analysis to 25 (7 from PubMed, 7 from CINAHL, 11 from ProQuest). The final group for analysis was 25.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38461420058&p=1pl&v=1&x=fduSJGHnYUMWhEvhC1z2fQ
10.1126/scirobotics.aar3018,Computer_Science_easy_485,The Millidelta isn't the first miniaturized form of the popular Delta design.,"Furthermore, an average RMS deviation from the desired trajectory (RMS accuracy) as low as 24.7 ± 0.2 mm (n = 5) was achieved.","But in some regard, the Millidelta's size is a big advantage and its ability to fold up in origami fashion make it ideal for conserving space. The Millidelta isn't the first miniaturized form of the popular Delta design. The Millidelta's speed advantage is the most tantalizing result from the recent study, according to the team which develop the robot.","At low frequencies, the milliDelta was able to repeat trajectories with an average RMS deviation from the mean trajectory (RMS precision) down to 1.9 ± 0.5 mm (n = 5). Furthermore, an average RMS deviation from the desired trajectory (RMS accuracy) as low as 24.7 ± 0.2 mm (n = 5) was achieved. These values demonstrates the milliDelta's ability to perform motions necessary for pick and place at a frequency higher than those of currently available Delta robots.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33051935778&p=1pl&v=1&x=OY80c78WXnFgvRG5B5QUhQ
10.1038/s41551-018-0258-2,Computer_Science_easy_486,"""You can administer a drug to turn off neural cells of interest, but, with time, those cells will turn back on.","These results demonstrate spatially selective, CNO-dependent, intersectional neuromodulation in a Cre mouse line.","""This method is reversible,"" says Szablowski. ""You can administer a drug to turn off neural cells of interest, but, with time, those cells will turn back on. You can also perform drug dosing to determine how completely you are shutting off that region of the brain.""","We found no activation after saline administration ( Supplementary Fig. These results demonstrate spatially selective, CNO-dependent, intersectional neuromodulation in a Cre mouse line. Consistent with previous findings 54 , the majority of these sites (71.4%) had normal histology ( Supplementary  Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34501523368&p=1pl&v=1&x=6E8TJ8Q4dZWsjsT4ygCpvQ
10.1126/scirobotics.aaw2388,Computer_Science_easy_488,"4, eaaw2388 (2019)

By plowing away the degraded remains of the biofilm, Koo says, the chance of it taking hold and re-growing decreases substantially.","4 , B and D).","Fluorescent microscopy confirms the complete removal of bacteria from the CAR-""raked"" surfaces. 4, eaaw2388 (2019)

By plowing away the degraded remains of the biofilm, Koo says, the chance of it taking hold and re-growing decreases substantially. They have really done a fantastic job on the project.""","By defining a trajectory that started at the center of the workspace and progressively swept outward in a concentric manner, the biohybrid CARs cleared the biofilm biomass away from the contaminated surface (Fig. 4 , B and D). The absence of bacteria over the surface after the biohybrid CAR's displacement was confirmed with lack of fluorescent signal from SYTO 9-labeled bacteria (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39073685616&p=1pl&v=1&x=QGiEkDB4E5vngDVtihUW7w
10.1038/s41598-017-01265-7,Computer_Science_easy_489,"Good for the heart: dog owners tend to exercise more Credit: Gary John Norman

Simply put, dogs that need a long walk every day tend to have more healthy owners.","After the perturbation on the compliant support body sway was affected by the interaction between light touch and vision ( for the SVE (11%), while its impact in DVE and NVE did not differ significantly from each other (Fig.","The researchers believe the improvement in cardiovascular health and the consequent life expectancy is driven by how demanding a given breed of dog is to exercise. Good for the heart: dog owners tend to exercise more Credit: Gary John Norman

Simply put, dogs that need a long walk every day tend to have more healthy owners. The research also showed a striking correlation between health and dog ownership among people living on their own, revealing a 33 per cent reduction in the risk of early death.","It reduced rapidly in the NVE trials to the same final level as for the SVE, but was significantly higher for the DVE immediately following the perturbation (15%) and in the 3 rd and 4 th time bins after it (26% and 45% respectively) (Fig. After the perturbation on the compliant support body sway was affected by the interaction between light touch and vision ( for the SVE (11%), while its impact in DVE and NVE did not differ significantly from each other (Fig. Light touch had no effect on the time it took the participants to stabilise ( Table 2) .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32556421336&p=1pl&v=1&x=6JcM27IPbzf3PFpyUmGqDw
10.1016/j.neuroimage.2015.10.090,Computer_Science_easy_490,It can increase your independence and knowledge of the local area and improve your access to the natural (or urban) environment.,"In T1-weighted MRI scan, myelin is most apparent in the white matter, however there are also a considerable number of myelinated fibers within hippocampal grey matter .","Electric Bikes Can Boost Older People's Well-Being

Getting out on the open bike path, with some batteries, can recharge the brain and body

Getting on your bicycle can give you an enormous sense of freedom and enjoyment. It can increase your independence and knowledge of the local area and improve your access to the natural (or urban) environment. It can also be highly nostalgic--reminding you of your childhood cycle rides and the joy of being young.","We cannot rule out the possibility that these or other micro-structural changes, that we have not tested here, could also contribute. In T1-weighted MRI scan, myelin is most apparent in the white matter, however there are also a considerable number of myelinated fibers within hippocampal grey matter . It is possible that such mechanisms explain the changes in myelin associated with experience that have been reported in several recent imaging studies .",[1],Computer_Science,train,1.0,news,https://www.theepochtimes.com/electric-bikes-can-boost-older-peoples-well-being_2875201.html
10.1126/scirobotics.aat3536,Computer_Science_easy_491,"For drones, mastering synchronized flight may be a crucial first step to mastering real-world delivery routes.",These tolerance,"Whether you find flocks of birds terrifying or mystifying, you can objectively say that theyare pretty skilled at not ramming into each other mid-flight. For drones, mastering synchronized flight may be a crucial first step to mastering real-world delivery routes. aWhen the first cars appeared on the streets people were walking in front of them and ringing a bell that cars were coming, but soon there we a diversity of cars moving in coordinated ways throughout cities, something similar is going on with drones,a VA!sA!rhelyi says.","With these transfer functions, we can construct a singleobjective fitness function that takes into account all necessary requirements of safe flocking behavior: These tolerance values can be chosen arbitrarily, depending on the absolute and relative importance of the partial fitness components in the optimization.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34574394997&p=1pl&v=1&x=5sfFUaHtnYLCAwdn6y78nQ
10.1287/orsc.2014.0951,Computer_Science_easy_492,"The 2019 Academy Awards will air on February 24, after a long and sometimes tedious awards season.","Second, rather than stratifying the data using marriage number, we also used a continuous variable to control for marriage number, which has the advantage of controlling for occurrence dependence (we could not control for both marriage and divorce number because divorce number equals marriage number minus one) .","Winner Marcia Gay Harden even called winning "" disastrous on a professional level."" The 2019 Academy Awards will air on February 24, after a long and sometimes tedious awards season. While there are some films and actors we at INSIDER believe were snubbed, perhaps they should be thanking their lucky stars.","Using a depreciation constant of 0.25, for example, the Oscar effect in a two-year-old marriage would be depreciated with a factor of 0.61 (exp(-0.25 x 2)), whereas the effect would be depreciated with a factor of 0.37 (exp(-0.25 x 4) in a four-year-old marriage. Second, rather than stratifying the data using marriage number, we also used a continuous variable to control for marriage number, which has the advantage of controlling for occurrence dependence (we could not control for both marriage and divorce number because divorce number equals marriage number minus one) . The results are robust regardless of approach, thus suggesting that we report the results using the more informative second approach.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38600946079&p=1pl&v=1&x=kVIvrdgQDU_Ycxyu8tvq4g
10.1136/amiajnl-2013-002033,Computer_Science_easy_494,The new findings could provide relief to millions of Americans each year by allowing doctors to offer patients early intervention.,"BP varies throughout the course of a 24-h day (it is highest in the evening and lowest in the morning) with additional intrinsic, random variation of between 5 and 15 mm Hg depending on patient characteristics, acute illness, medications, and methods of measurement.","By utilizing RNN, the algorithm can anticipate early stages of heart failure, which will ultimately lead to better preventative care for patients at risk of heart disease. The new findings could provide relief to millions of Americans each year by allowing doctors to offer patients early intervention. ""This is a preliminary work, it showed potential that it can do better than classical models--it makes a good promise for how deep learning can make a positive impact in the health care industry,"" says Choi.","We show how both types of transition can be utilized as target labels to build predictive models. BP varies throughout the course of a 24-h day (it is highest in the evening and lowest in the morning) with additional intrinsic, random variation of between 5 and 15 mm Hg depending on patient characteristics, acute illness, medications, and methods of measurement. 3.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/deep-learning-heart-failure-1707242/
10.1016/j.rse.2018.06.028,Computer_Science_easy_496,"No animal left uncounted

The drones make it possible to cover vast areas economically.","We found the random forest to provide a similar performance as reported in , which can also be seen in the precision-recall curves in Figure 12 .","""Automating part of the animal counting makes it easier to collect more accurate and up-to-date information."" No animal left uncounted

The drones make it possible to cover vast areas economically. In the other images, the algorithm highlights the patterns most likely to be animals.","We use the same object proposals and feature extraction methods proposed in the original work, but replace the original exemplar SVM with a random forest classifier, which is a solid baseline in remote sensing, providing nonlinear response at no extra computational expense . We found the random forest to provide a similar performance as reported in , which can also be seen in the precision-recall curves in Figure 12 . Figure 9 illustrates the results obtained by the CNNs described in Section 4.1.1 on the complete test set.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34515779371&p=1pl&v=1&x=6YmyGM97J5AdZjcXfWUvIg
10.1177/0018720815587803,Computer_Science_easy_497,"aWe are absolutely certain that the use of deep-learning machines is going to allow us to have a better understanding of ISIL as a network and better understanding about how to target it precisely and lead to its defeat,a said Secretary Work, according to DoDas website.","However, these differences in performance did not manifest in the nongaming population.","It is a at one time a leading the charge toward machine learning and also trying desperately to keep up. aWe are absolutely certain that the use of deep-learning machines is going to allow us to have a better understanding of ISIL as a network and better understanding about how to target it precisely and lead to its defeat,a said Secretary Work, according to DoDas website. But the military has an advantage: resource.","Gamers in the negative-priming group understood the imperfections in the automation, reporting lower trust in the AS. However, these differences in performance did not manifest in the nongaming population. One potential reason is that gamers may have a higher propensity to overtrust automation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34019770452&p=1pl&v=1&x=DoNAUygF_ZqBKtxb2dJb6w
10.1016/j.neuroimage.2014.03.080,Computer_Science_easy_498,"""I have never been called names like that in my entire life,"" says Cikara of her New York visit.","Typically, individuals show better subsequent memory for items encoded with regard to the self, compared to other encoding conditions; this memory advantage is associated with mPFC activation.","Cikara and her colleagues may have discovered a culprit we can't control: our brains. ""I have never been called names like that in my entire life,"" says Cikara of her New York visit. When people feel they will not be recognized or called to answer for their actions, they are more likely to behave wantonly.","These results are consistent with the complexity of intergroup behavior, demonstrating that for some but not all individuals, competing in a group is associated with reduced mPFC response to self-relevant moral stimuli, and this reduction is associated with a greater propensity to harm competitors. Typically, individuals show better subsequent memory for items encoded with regard to the self, compared to other encoding conditions; this memory advantage is associated with mPFC activation. Consistent with past research, we observed a positive correlation across individuals between the self-reference effect in memory and the self-reference effect in mPFC in the ""alone"" condition, r(19)=.47, p=.03.",[1],Computer_Science,train,1.0,news,http://www.medicaldaily.com/mob-mentality-brain-suppresses-personal-moral-code-when-groups-288342
10.1136/amiajnl-2012-001419,Computer_Science_easy_499,Battery power lasts about a day per charge.,New scenarios will be offered and evaluated.,"Battery power lasts about a day per charge. Of course, there have been parodies of the user experience but I believe that clinicians can successfully use Google Glass to improve quality, safety, and efficiency in a manner that is less bothersome to the patients than a clinician staring at a keyboard. Electronic Medication Admission Records must include the use of ""assistive technology"" to ensure the right dose of the right medication is given via the right route to the right patient at the right time.","In that this paper is a conceptual typology of problem scenarios, data source limitations are obvious but only temporarily problematic. New scenarios will be offered and evaluated. To our knowledge, this is a new typology, incorporating the commonalities of HIT functions and medical workflow.",[1],Computer_Science,train,1.0,news,http://health.usnews.com/health-news/hospital-of-tomorrow/articles/2013/07/29/the-healthcare-it-applications-of-google-glass
10.1073/pnas.1714958115,Computer_Science_easy_500,"While the authors do not identify the means of this communication, they suggest it may be a consequence of root grafting, where roots intertwine.","Because of the mutualistic interactions, both the pollinator and plant will survive, and the network system does not exhibit a tipping point.","The Ising model makes quantitative predictions of how neighbor-to-neighbor interactions can create alignments over large distances. While the authors do not identify the means of this communication, they suggest it may be a consequence of root grafting, where roots intertwine. Grafting may help one tree ""tell"" another that it's time to produce, which may help neighboring trees synchronize their production.","The reason is precisely mutualistic interactions: even if there is only one remaining pollinator, at least one plant will be connected with this pollinator. Because of the mutualistic interactions, both the pollinator and plant will survive, and the network system does not exhibit a tipping point. In this parameter regime, the small migration rate has no effect on system dynamical features, such as the absence of a tipping point.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/ising-model-trees-synchrony-1674302/
10.1089/soro.2017.0120,Computer_Science_easy_501,But birds illustrate another strategy that is just as effective for flying through bottlenecks.,4) .,"It paves the way for a new generation of large robots that can move through narrow passages, making them ideal for exploration as well as search and rescue missions. But birds illustrate another strategy that is just as effective for flying through bottlenecks. They can quickly fold their wings during high-speed flight, reducing their imposing span, to easily negotiate the challenging paths before them.","In our prototype, the fully folded structure (i.e., c ¼ 90 ) can adopt a wingspan l ws equal to 128 mm, which corresponds to a folding ratio of g ¼ 48%, whereas the wingspan of the unfolded structure (i.e., c ¼ 0 ) is equal to 268 mm (Fig. 4) . In other words, the folded robot is more than two times smaller than the unfolded robot, which means that the robot can theoretically pass through a gap two times smaller than its usual wingspan.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34200283269&p=1pl&v=1&x=VW4XyG2fRbfomTJtL7lGAA
10.1145/2976749.2978392,Computer_Science_easy_502,"Next year, it will make its Olympic debut in Tokyo.","Rather, our adversary can alter only the composition of inputs to be classified based on her knowledge of the classification model, potentially derived by examining the entire model or by observing its outputs for some inputs.","That sounds quite Big Brother. Next year, it will make its Olympic debut in Tokyo. But there is more to it than flashy new technology.","That is, the adversary cannot ""poison"" the FRS by altering training data, injecting mislabeled data, etc. Rather, our adversary can alter only the composition of inputs to be classified based on her knowledge of the classification model, potentially derived by examining the entire model or by observing its outputs for some inputs. On the other hand, different assumptions can plausibly be made about the adversary's knowledge of the feature space and the trained classification model.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39810627006&p=1pl&v=1&x=Oo7iJ5mIFAkqFFX1vQhPeg
10.1126/sciadv.1602368,Computer_Science_easy_503,What was particularly surprising as that the memory effect had a larger impact on the number of views than the main event.',"Our analysis has also been applied to the complete set of sources, which yielded the following changes to the results: The average view flow is a full scale smaller, and the noise is a bit more dominant.","Anders Mollgaard, a co-author from the Niels Bohr Institute in Denmark, said: 'Our work shows that different topics are connected to each other through memory and association, thereby forming an interconnected network of topics. What was particularly surprising as that the memory effect had a larger impact on the number of views than the main event.' ###

Notes to Editors:

The paper, 'The memory remains: Understanding collective memory in the digital age', is by Ruth Garcia-Gavilanes et al.","We removed all sources below the 11th largest source because the natural noise of the target views dominates in this region, as illustrated in Fig. Our analysis has also been applied to the complete set of sources, which yielded the following changes to the results: The average view flow is a full scale smaller, and the noise is a bit more dominant. The effects of categories and geography are enhanced, whereas the superlinear effect of the previous views on the view flow almost disappears.",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/research-into-why-we-remember-some-aviation-disasters-and-forget-others/
10.1126/scirobotics.aaw1977,Computer_Science_easy_505,"And while the new study focused on a potential heart use, Duvvuri said adding that sensing technology to catheters could have other uses, such as helping to diagnose risky growths in the colon.","The Pearson's coefficient was equal to 0.97, which indicates a strong linear relationship.","Still, true autonomy, ""in my humble opinion, it's still a hammer looking for a nail,"" said Duvvuri, who couldn't think of an area where it would improve a procedure. And while the new study focused on a potential heart use, Duvvuri said adding that sensing technology to catheters could have other uses, such as helping to diagnose risky growths in the colon. Added Hopkins' Taylor, ""I see things evolving where the machine keeps undertaking more and more discrete tasks while working in partnership with the humans.""","7C) . The Pearson's coefficient was equal to 0.97, which indicates a strong linear relationship. 7C indicates that the contact duty cycle range of 0.35 to 0.45 that we used in most of our experiments corresponded to a maximum force of 1.25 to 2.3 N.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39075418967&p=1pl&v=1&x=CM3WTAK3r3ljmG11PCsaUg
10.1126/scirobotics.aat4440,Computer_Science_easy_506,"The results showed that the robots could perform these tasks well, with activation of the muscles leading to flexing of a finger-like protuberance at the end of the robot by around 90deg.","Consequently, it is difficult to achieve compatibility between large actuation and a long lifetime in a biohybrid robot.","""The fact that they were exerting opposing forces on each other stopped them shrinking and deteriorating, like in previous studies."" The results showed that the robots could perform these tasks well, with activation of the muscles leading to flexing of a finger-like protuberance at the end of the robot by around 90deg. Credit: 2018 Shoji Takeuchi

""Our findings show that, using this antagonistic arrangement of muscles, these robots can mimic the actions of a human finger,"" lead author Yuya Morimoto says.","Thus, such a configuration is not suitable as a biohybrid actuator. Consequently, it is difficult to achieve compatibility between large actuation and a long lifetime in a biohybrid robot. The selective contractions of each skeletal muscle allow large actuation, and balancing the tension using antagonistic muscles prevents their spontaneous shrinkage over the long term.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34181638319&p=1pl&v=1&x=XmcYh8okiuswguHCGGOF7A
10.1038/nature07127,Computer_Science_easy_507,"And the way the document spells out the applications can also help researchers explain their proposals to potential investors, he says.",This course of action surely fails because of the exponential growth in ρ(t) with the size of the network.,"""It gives us a new vocabulary for understanding what we are developing."" And the way the document spells out the applications can also help researchers explain their proposals to potential investors, he says. ""With this roadmap, we can have this conversation.""","Perhaps surprisingly, a nontrivial task will be simply to answer the question ""Does it work?"" This course of action surely fails because of the exponential growth in ρ(t) with the size of the network. We might instead follow a strategy based upon more functional issues of algorithmic capability.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37514741529&p=1pl&v=1&x=2cXWkbJcWF9BgwLxLN53Yg
10.1126/sciadv.aar8260,Computer_Science_easy_508,"When tested on a wide range of synthetic and real-world datasets, ranging from teams in an NCAA college basketball tournament to the social behavior of animals, SpringRank outperformed other ranking algorithms in predicting outcomes and in efficiency.","In our case, f(s i − s j ) is a Gaussian centered at 1, and the posterior converges to the multivariate Gaussian Eq.","When tested on a wide range of synthetic and real-world datasets, ranging from teams in an NCAA college basketball tournament to the social behavior of animals, SpringRank outperformed other ranking algorithms in predicting outcomes and in efficiency. But it's more complicated than simply assigning the highest ranking to the team that won the most games; after all, a team that exclusively plays low-ranked teams may not deserve to be at the top. Because physicists have long known the equations that describe the motions of springs, says De Bacco, the algorithm is easy to implement.","5. In our case, f(s i − s j ) is a Gaussian centered at 1, and the posterior converges to the multivariate Gaussian Eq. If hierarchical structure plays an important role in a system, then it should allow us to predict the direction of previously unobserved interactions, such as the winner of an upcoming match or which direction social support will flow between two individuals.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34596881216&p=1pl&v=1&x=X4MmlvIjGnCBCCFgFJlksw
10.1016/j.neuroimage.2016.05.053,Computer_Science_easy_509,"Since the shape descriptors of BrainPrint are more sensitive to subtle changes within a structure than are standard volume-based measures, they are better suited to quantify early disease effects and predict future progression, which opens up new research directions into the mechanisms that cause these asymmetries.",", λ η ).","Increased asymmetry was also associated with poorer cognitive test scores and with increased cortical atrophy. Since the shape descriptors of BrainPrint are more sensitive to subtle changes within a structure than are standard volume-based measures, they are better suited to quantify early disease effects and predict future progression, which opens up new research directions into the mechanisms that cause these asymmetries. For example, in addition to asymmetric distribution of amyloid beta, which has been reported, the differences could reflect disease subtypes that affect hemispheres differently.""","These properties make the shapeDNA well suited for comparing shapes, as initial alignment of the shapes can be completely avoided. , λ η ). Depending on the number of eigenvalues l computed, we can easily end up with thousands of values in the BrainPrint, which may make the approach more susceptible to overfitting.",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/advanced-analysis-of-brain-structure-shape-may-track-progression-to-alzheimers-disease/
10.1038/s41593-018-0209-y,Computer_Science_easy_510,"For further information, please contact the cited source.",We found the average variability for all body parts to be very small 2.69 ± 0.1 pixels (mean ± s.e.m.,"The software toolbox can be used with minimal to no coding experience and is freely available at mousemotorlab.org/deeplabcut. Note: material may have been edited for length and content. For further information, please contact the cited source.","Yet, accurately tracking the snout as a mouse samples the ""odorscape"" is crucial for studying odor-guided navigation. We found the average variability for all body parts to be very small 2.69 ± 0.1 pixels (mean ± s.e.m. The RMSE across two trials of annotating the same images is referred to as 'human variability' (note that the variability differs slightly across body parts).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=35000299954&p=1pl&v=1&x=W84_JJVq9W_-K8zSWhAe6A
10.1126/scirobotics.aan4545,Computer_Science_easy_511,But geckos might be able to help.,"This design yields a nearly constant torque in both directions, a large hysteresis during loading and unloading cycles, and a nearly zero steady-state position error.","But geckos might be able to help. When tested in zero-gravity airplane flight, the device was able to grasp and release floating cubes, cylinders, and spheres without affecting their motion. On Earth, the gripper was able to attach to, push, and release 800-pound robots meant to simulate drifting space debris.","A simplified model of the loading and unloading curve of a pretensioned SMA wire is illustrated in the gray shaded region. This design yields a nearly constant torque in both directions, a large hysteresis during loading and unloading cycles, and a nearly zero steady-state position error. Although a wrist with viscous damping absorbs energy well, it is not capable of stiff manipulation during gentle motions because its compliance is linear.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38720485901&p=1pl&v=1&x=abfI1Td9gCRrj-pmNeUv1g
10.1007/978-3-319-65127-9_19,Computer_Science_easy_512,No programming skills are needed for this.,"The 4G/LTE is vulnerable to active privacy attacks by IMSI Catcher, and we found that these attacks can be done quite easily and therefore can impact the confidence and reliability of commercial mobile networks.",They can also be used to eavesdrop on conversations and intercept texts. No programming skills are needed for this. But researchers demonstrated that 4G is also vulnerable to cell site simulator attacks using the same techniques that made 3G devices vulnerable by jamming preferred frequencies to force the target cell phone to use a lower frequencies.,"In conclusion, our experiments have verified, independently of other works, that IMSI-catching indeed can be done for the 4G/LTE system too. The 4G/LTE is vulnerable to active privacy attacks by IMSI Catcher, and we found that these attacks can be done quite easily and therefore can impact the confidence and reliability of commercial mobile networks. We showed that these attacks are not limited to clever programmers with special hardware.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38070109527&p=1pl&v=1&x=y7bPE0Bq0R6Ascd6Ld-gew
10.1088/1741-2560/10/2/026011,Computer_Science_easy_513,"""Ready, set"" was unnecessary -- the neurons simply said, ""Go!""","In the path reversals panel, the extremities of the confidence interval overlap with the median because the median value comprises a large proportion of the total number of observations (observations are integer values).","When the monkeys did not know what to expect, their neurons behaved differently. ""Ready, set"" was unnecessary -- the neurons simply said, ""Go!"" ""This study changes our view of how movement is controlled,"" Ames stated in a press release.","For each level of delay (horizontal axis), median performance for τ = 0 (blue circle) and for τ = 100 or 200 (red diamond) are shown, with 95% confidence intervals for the median. In the path reversals panel, the extremities of the confidence interval overlap with the median because the median value comprises a large proportion of the total number of observations (observations are integer values). Columns of asterisks indicate the level of significance for a comparison between the present prediction and future prediction condition (p < 0.05, p < 0.01 and p < 0.001 for one, two and three asterisks, respectively).",[1],Computer_Science,train,1.0,news,http://www.medicaldaily.com/prosthetic-limbs-redesigned-engineers-research-possibility-brain-controlled-limbs-267671
10.1038/35019019,Computer_Science_easy_514,"Circulation, an obvious measure of success for an institution established to lend books to people, is down.","The fact that s ≃ 1 for most f indicates that the network is deflated by nodes breaking off one by one, the increasing error level leading to the isolation of single nodes only, not clusters of nodes.","If you looked at how many people check books out of libraries these days, you would see failure. Circulation, an obvious measure of success for an institution established to lend books to people, is down. But if you only looked at that figure, you'd miss the fascinating transformation public libraries have undergone in recent years.","For random failures no threshold for fragmentation is observed, rather the size of the largest cluster slowly decreases. The fact that s ≃ 1 for most f indicates that the network is deflated by nodes breaking off one by one, the increasing error level leading to the isolation of single nodes only, not clusters of nodes. Thus, in contrast with the catastrophic fragmentation of the exponential network at f c , the scale-free network stays together as a large cluster for very high values of f , providing additional evidence of the topological stability of these networks under random failures.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39827226044&p=1pl&v=1&x=huiJFLEFl1uI5cdWiappGg
10.1145/2517312.2517319,Computer_Science_easy_515,The human ability to recognize patterns far outstrips anything that computers can do and matching this with the user's interpretation of random patterns is clever.,"After the Inkblots ⟨I π(1) , .",That's an interesting idea. The human ability to recognize patterns far outstrips anything that computers can do and matching this with the user's interpretation of random patterns is clever. But it does raise the question of how well people will remember their original interpretation of an inkblot.,"However, in this case the adversary might fail to crack the password because the GOTCHA solver found the wrong solution to one of the challenges. After the Inkblots ⟨I π(1) , . , ℓ π(k) ⟩ = H ( ⟨I π(1) , .",[1],Computer_Science,train,1.0,news,http://www.salon.com/2013/10/14/dear_computer_hackers_gotcha_newscred/
10.1126/science.aau5347,Computer_Science_easy_516,"On other words, herbivores need to keep a close eye at each other in order to stay within their protective group.",is in good agreement with our simulations of point-like particles.,"The physicists thus created particles with the broad field of view of herbivores and found that they stay together only by lowering their threshold of reaction. On other words, herbivores need to keep a close eye at each other in order to stay within their protective group. With their simple model, it is also explained how the narrow vision of predators is an advantage to detect the presence of preys over long distances.","However, at high a, hsi/N sharply decreases, indicating the loss of the single group in favor of small aggregates. is in good agreement with our simulations of point-like particles. Group formation breaks down when the perception of particles being too far from the group center never exceeds the threshold, regardless of their orientation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38922197322&p=1pl&v=1&x=AJyBPKZ-51JpdR1fJZyScA
10.1016/j.jcp.2018.12.009,Computer_Science_easy_518,"""This new research will enable more accurate and capable virtual experiments of the evolution and treatment of cells--cancerous or healthy--in response to a variety of candidate drugs.","Remarkably, this representation qualifies for a multi-scale characterization of electropermeabilization.","The same kind of electrical pulses could offer more efficient and effective delivery of drugs to fight disease. ""This new research will enable more accurate and capable virtual experiments of the evolution and treatment of cells--cancerous or healthy--in response to a variety of candidate drugs. Eventually, electric pulsation might also be used to accelerate the healing of combat wounds.""","Their description determines the local behavior of each cell membrane under the influence of its surrounding electric potential in a continuous manner. Remarkably, this representation qualifies for a multi-scale characterization of electropermeabilization. However, we note that in practice these models embody calibrations of free parameters that are tuned by experimenting on populations of cells and extending these measurements to single-cell scale, oversighting the multi-scale nature of electropermeabilization in the experiments.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/electroporation-simulations-2108122/
10.1038/nature19791,Computer_Science_easy_519,"Executing so many calculations simultaneously would be virtually impossible without Mira's computing power, according to Mulligan.","In all three cases, the NMR spectra had well-dispersed, sharp Structures for gEHE_06, gEEH_04, gEEHE_02 and gHHH_06 were determined by NMR spectroscopy, and the structure of gEHEE_06 was determined by X-ray crystallography.","Though he was not a coauthor on the Nature paper, Alexeev helped Baker's team scale up previous programs it had used to design proteins for modeling peptides on Mira. Executing so many calculations simultaneously would be virtually impossible without Mira's computing power, according to Mulligan. Baker and his colleagues had tasked Mira with modeling millions of potential peptide conformations before, but this study stands out for two reasons.","4 ) and had a large energy gap in the structure prediction calculations. In all three cases, the NMR spectra had well-dispersed, sharp Structures for gEHE_06, gEEH_04, gEEHE_02 and gHHH_06 were determined by NMR spectroscopy, and the structure of gEHEE_06 was determined by X-ray crystallography. b, Cartoon representation of the lowest energy conformer of each NMR ensemble or crystallographic asymmetric unit (grey) is shown aligned to the design model (rainbow).",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/NEtMYOuW-yc/
10.1016/j.diin.2016.07.002,Computer_Science_easy_520,"This was reasonably funny as a story arc on Arrested Development, when photos purported to be of an Iraqi landscape turned out to show merely a pair of testicles.","However, similarity retrieval and hash-based approaches appear not directly suitable for detecting new or previously unknown media files, because both techniques require the availability of (similar) media files to be indexed or hashed.","This was reasonably funny as a story arc on Arrested Development, when photos purported to be of an Iraqi landscape turned out to show merely a pair of testicles. But the sooner that AI becomes sophisticated enough to separate images of sexual abuse from ones of the desert, the better. Human bodies are a good deal less uniform than more easily recognizable shapes like guns.","By applying a query-by-example technique, visually similar or identical images with respect to the given query can be retrieved. However, similarity retrieval and hash-based approaches appear not directly suitable for detecting new or previously unknown media files, because both techniques require the availability of (similar) media files to be indexed or hashed. This in turn renders these files as already known.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32820906645&p=1pl&v=1&x=f2pM_qTxuk8BvPsemIhuUw
10.1038/nature12966,Computer_Science_easy_521,"While some mice could produce antibodies against the virus, none of their antibodies could neutralize the virus.","Although 17-HD9 and mota bury a similar amount of area on the epitope (690 Å 2 versus 683 Å 2 ), 17-HD9 uses a different paratope to make more hydrogen bonds (15-18 versus 7) that plausibly contribute to its higher scaffold affinity and higher neutralization potency ( Fig.","Unless that it is, if they are against those epitopes (the parts of the pathogen targeted by the immune system) crucial for viral survival, what means that they cannot be changed. While some mice could produce antibodies against the virus, none of their antibodies could neutralize the virus. In contrast, after a few vaccination rounds with the new structures the majority of the macaques were producing neutralizing antibodies what was very promising considering the similarity between our immune systems

""Actually the macaques were producing antibodies more potent than the prophylactic antibody that is used to treat high risk patients, the one from where we started,"" says Correia, ""This when the natural infection exposes multiple viral epitopes, while our scaffolds only have a single epitope supposedly triggering a much more limited immune response.","The , and 85% of the epitope residues buried by either mota or 17-HD9 are also buried by the other ( Fig. Although 17-HD9 and mota bury a similar amount of area on the epitope (690 Å 2 versus 683 Å 2 ), 17-HD9 uses a different paratope to make more hydrogen bonds (15-18 versus 7) that plausibly contribute to its higher scaffold affinity and higher neutralization potency ( Fig. The 17-HD9 complexes are also consistent with the ability of 17-HD9 to bind to the K82E mota escape mutant: density for the K82 side chain is absent in two out of four 17-HD9 complexes, and K82 is only 37% buried by 17-HD9 in the other two complexes (Fig.",[1],Computer_Science,train,1.0,news,http://www.science20.com/catarina_amorim/personalized_vaccine_vaccine_design_gets_turned_its_head-129214
10.1016/j.jbi.2015.05.016,Computer_Science_easy_524,"The clinically validated attributes and risk score are available to all types of healthcare organizations - providers, payers, pharmacy and life sciences.","In particular, in elastic net the coefficientsb are found by 235 solving: which would give slightly better performance.","The clinically validated attributes and risk score are available to all types of healthcare organizations - providers, payers, pharmacy and life sciences. With real-time socioeconomic information, the cutting-edge data analytics model can help caregivers make immediate care decisions, including helping to assess the likelihood of a patient being readmitted to the hospital within 30 days. ""That could include someone doing discharge planning having access to the readmission risk score while the patient is still in the hospital or a pharmacist providing a consultation at the counter.""","forces some coefficients to be exactly zero. In particular, in elastic net the coefficientsb are found by 235 solving: which would give slightly better performance. However, 263 suggests this value is relatively robust, and we decided not to 264 tune it to save on computation costs, since our results using this 265 value were quite good.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37903313249&p=1pl&v=1&x=j33LdtuqNi1nN0JzwRLFZQ
10.1093/bioinformatics/btw399,Computer_Science_easy_525,"""It doesn't have to be this way,"" Dr. Gatherer said.",Shannon entropy values range from 4.3 (all amino acids equally represented at a site) to 0.0 (invariant site with only one allowed residue).,"We know this method is safe, and that it works reasonably well most of the time,"" Dr. Gatherer explained in a statement. ""It doesn't have to be this way,"" Dr. Gatherer said. Our collaboration has found a way to select epitopes reaching full population coverage.""","Sequences for each influenza A protein type were clustered with 96-99% sequence similarity. Shannon entropy values range from 4.3 (all amino acids equally represented at a site) to 0.0 (invariant site with only one allowed residue). As a result, we obtained consensus sequences with variable positions, H > 0, masked.",[1],Computer_Science,train,1.0,news,http://www.redorbit.com/news/health/1113416069/universal-flu-vaccine-100216/
10.1073/pnas.0403723101,Computer_Science_easy_527,"Change is long overdue.""","Our perspective-heuristic framework is not minimal, because we show in an earlier paper (8) that two problem solvers with distinct perspectives and heuristics can act identically in the space of solutions.","Diversifying science brings with it the possibility of changing science itself."" Change is long overdue."" Diversity enhances the capacity of science to better understand the processes of the world.","A diverse group is one whose agents' mappings are diverse. Our perspective-heuristic framework is not minimal, because we show in an earlier paper (8) that two problem solvers with distinct perspectives and heuristics can act identically in the space of solutions. However, the advantage of the full framework is that it generalizes models in the computer science literature that focus on diverse heuristics (1, 2), and models in the organizational behavior and psychology literature, which often emphasize diverse perspectives (3, 4, 6).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38744591049&p=1pl&v=1&x=3RrJlf6OjZCjICeVObxFCw
10.1371/journal.pcbi.1005823,Computer_Science_easy_529,And the algorithms were able to identify one species--called Risso's dolphin--by sound alone.,27].,"""Yeah, more than i would like to spend my time sifting through."" And the algorithms were able to identify one species--called Risso's dolphin--by sound alone. [Kaitlin E. Frasier et al., Automated classification of dolphin echolocation click types from the Gulf of Mexico]

Traditional marine mammal surveys scan surface waters from a boat, and extrapolate from there.","Third, site-specific conditions do not offer an explanation for the consistent relationships between click type spectral shape and ICI distributions across deployments spanning multiple years, or why ICI distributions have consistent modal values. 27]. Species differences may explain these observations.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32776613231&p=1pl&v=1&x=ZJ8HWWr9gTkhDlq0Z-Ob_Q
10.1038/srep34468,Computer_Science_easy_534,"""This approach uses something we do normally -- interacting with a digital device -- so it does not add any additional burden or take time away from daily activities,"" he says.","Choosing spouses allowed us to limit the effect of confounding variables, such as age, education and gender.","In this way the technique, which is based on technology originally developed to replace computer passwords, allows Parkinson's signs to be monitored as people perform ordinary tasks such as typing emails or updating their Facebook status, according to Luca Giancardo, a former Catalyst Fellow in the Madrid-MIT M+Vision Consortium in the Research Laboratory of Electronics at MIT, and one of the paper's lead authors. ""This approach uses something we do normally -- interacting with a digital device -- so it does not add any additional burden or take time away from daily activities,"" he says. Medication to replace dopamine levels or mimic dopamine's activity can help to lessen the severity of its signs.","Additionally, being able to measure PD symptoms privately, without having to use a dedicated tool visible to co-workers will reduce the stigma of the disease, especially at the early stages . Choosing spouses allowed us to limit the effect of confounding variables, such as age, education and gender. Table 1 shows a summary of these confounding variables for the PD and control groups.",[1],Computer_Science,train,1.0,news,http://news.mit.edu/2016/keyboard-monitoring-parkinsons-symptoms-1005
10.1073/pnas.1408071112,Computer_Science_easy_536,"""As we count proteins in groups and assess how they assemble, we will be moving toward ways of diagnosing group-size anomalies associated with disease.""","A short time later, the fluorophore irreversibly photobleaches.","""As we count proteins in groups and assess how they assemble, we will be moving toward ways of diagnosing group-size anomalies associated with disease."" ""Super-resolution imaging techniques are way ahead of analysis techniques,"" Presse said. Counting these proteins in a group should be as easy as counting light bulbs except that these light bulbs flicker.","The light stochastically triggers fluorophore activation. A short time later, the fluorophore irreversibly photobleaches. The low probability of photoactivation ensures that two fluorophores separated less than the diffraction limit will most probably not emit simultaneously.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141222165435.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_health+%28ScienceDaily%3A+Top+Health+News%29
10.1016/j.neuroimage.2017.01.001,Computer_Science_easy_537,"""We think this study, and others like it, provide a good starting point for understanding possible treatments for memory disorders,"" Vaz said.",This amplitude should not be significantly impacted by the presence or absence of any high frequency oscillations.,"This was particularly true in a brain region known as the medial temporal lobe, a structure thought to play a critical role in the formation of both short-term and long-term memories. They found that during memory formation, brain activity became more disorganized in the frontal lobe, an area involved in executive control and attention, and in the temporal lobe, an area more implicated in memory and language. ""We think this study, and others like it, provide a good starting point for understanding possible treatments for memory disorders,"" Vaz said.","The amplitude of the phase-triggered average waveform reflects a combination of both the consistency and the strength of the modulating low frequency signal. This amplitude should not be significantly impacted by the presence or absence of any high frequency oscillations. We found that, in an exemplar electrode, the amplitude of the average waveform is significantly correlated with the extent to which PAC was measured across all trials (r=0.663, p < .001; Fig.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/nnaQ4U2c1ws/
10.1073/pnas.1800923115,Computer_Science_easy_538,"The algorithms developed in our work could also be put to use here,"" says Novati.","In the early stages of training (first 10000 transitions -green bars), the swimmer does not show a strong preference for maintaining any particular separation distance.","Verma emphasizes that the simulations didn't examine every aspect involved in the efficient swimming behavior of fish, but the algorithms they developed and the physics they learned more about could be useful for autonomously swimming or flying robots. An autonomous robot swimmer or flyer could handle unexpected flow situations--for example, when flying between buildings in high winds to deliver goods, or during search and rescue operations in stormy conditions. The algorithms developed in our work could also be put to use here,"" says Novati.","The smart-follower is capable of adapting to deviations in the leader's trajectory (Supplementary Movie S3), as these situations are encountered when performing random actions during training. In the early stages of training (first 10000 transitions -green bars), the swimmer does not show a strong preference for maintaining any particular separation distance. Towards the end of training (last 10000 transitions -lilac bars), the swimmer displays a strong preference for maintaining a separation-distance of either ∆x = 1.5L or 2.2L.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/swimming-fish-energy-flow-dynamics-1777052/
10.1038/s41598-018-31697-8,Computer_Science_easy_539,"Not only does it work for light scattering through a material, it would also work for light scattering off of a surface -- say the paint on a wall.","Furthermore, the results are largely unaffected by the motion of the scatterer, as can be seen by comparing them against the ground truth object.","The technique has many potential applications. Not only does it work for light scattering through a material, it would also work for light scattering off of a surface -- say the paint on a wall. This could allow security cameras to work around corners or even through frosted glass.","The single-shot coded ME approach, however, enables a clear understanding of the evolution of the scene (see Fig. Furthermore, the results are largely unaffected by the motion of the scatterer, as can be seen by comparing them against the ground truth object. For the results shown above, we typically set the camera integration time to approximately 100 s in order to overcome the readout detector noise on the CCD camera and achieve an excellent signal to noise ratio (SNR, typically 100).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37227233631&p=1pl&v=1&x=CYOiwBrYwvS_zCvYfelF7w
10.1136/jamia.2009.001750,Computer_Science_easy_540,We needed desperately to know the name of the microbe that was trying to kill her.,Duplicate testing occurred in 27/85 (32%) patients and was categorized as 'not clinically indicated' in 17/ 85 (20%) patients (table 2).,We needed desperately to know the name of the microbe that was trying to kill her. Critical minutes ticked by but the medical records manager of the other hospital insisted I send a distorted message via 19th-century technology before she would release the information. [C]ountless patients suffer the steely stabs of our needles as we repeat tests that they received just hours ago in different facilities.,A total of 833 ACHD patients were hospitalized under the guidance of the BACH service during the 2-year study time period. Duplicate testing occurred in 27/85 (32%) patients and was categorized as 'not clinically indicated' in 17/ 85 (20%) patients (table 2). Fifty percent of the patients with duplicative testing had more than one test duplicated.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39014071705&p=1pl&v=1&x=4yJ6ylqW3TV6CWieTsZCAQ
10.1126/science.aat4807,Computer_Science_easy_541,Secure computation done at such a massive scale could enable broad pooling of sensitive pharmacological data for predictive drug discovery.,"The top prediction from both methods was an interaction between the estrogen receptor (ER) and droloxifene, which had reached phase 3 clinical trials as an ER modulator for advanced breast cancer (25) .","Secure computation done at such a massive scale could enable broad pooling of sensitive pharmacological data for predictive drug discovery. Models can be trained to crunch datasets of known DTIs and then, using that information, find novel drug candidates. Cryptography methods to secure the data are so computationally intensive they don't scale well to datasets beyond, say, tens of thousands of DTIs, which is relatively small.","It will be interesting to find out whether this interaction is confirmed by other studies. The top prediction from both methods was an interaction between the estrogen receptor (ER) and droloxifene, which had reached phase 3 clinical trials as an ER modulator for advanced breast cancer (25) . All of our findings were obtained without revealing any information about the underlying drugs, targets, and interactions during the computation.",[1],Computer_Science,train,1.0,news,http://news.mit.edu/2018/cryptographic-protocol-collaboration-drug-discovery-1018
10.1038/srep03812,Computer_Science_easy_542,"""This is a great example showing how curiosity leads to innovative work.""",Fully reversible responses were observed after tens of bending cycles.,"""Now our students showed that this can be done simply with a pencil and paper -- and it works,"" Huang said. ""This is a great example showing how curiosity leads to innovative work."" Other applications of the pencil-and-paper technology could be more unconventional.","Similarly, the device exhibited a sharp drop in resistance when a compressive strain was applied followed by a rapid return to the base resistance when the strain was removed. Fully reversible responses were observed after tens of bending cycles. Upon exposure to VOCs, the polymer matrix is swollen, resulting in more separated carbon particles in the percolating network and thus increased resistance (Figure 5e ).",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140122202308.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1515/popets-2015-0007,Computer_Science_easy_543,But he wasn't finding much.,The top two URL+title pairs for the female group was for a generic job posting service and for an auto dealer.,"""If you are open for business, you can't discriminate against certain protected classes,"" Selbst said. But the disparate-impact doctrine does not apply to the online world, where it's often difficult to determine how and why different prices are being offered. But he wasn't finding much.",Google showed the ads 1852 times to the male group but just 318 times to the female group. The top two URL+title pairs for the female group was for a generic job posting service and for an auto dealer. The found discrimination in this experiment was predominately from a pair of job-related ads for the same service making the finding highly sensitive to changes in the serving of these ads.,[1],Computer_Science,train,1.0,news,http://www.theatlantic.com/education/archive/2015/09/princeton-review-expensive-asian-students/403510/
10.1038/s41586-019-0939-3,Computer_Science_easy_545,Because spatial disorientation and loss of memory are one of the first symptoms of Alzheimer's disease -- which destroys hippocampal neurons in its earliest stages -- these findings can further research efforts to understand the causes and potential cures for Alzheimer's and other neurodegenerative diseases.,"Under gain-adjusted conditions, CA1 units (7.2 ± 5.8 (mean ± s.d.)","The study's findings add additional evidence toward how memories, inherently grounded in time and space, are formed. Because spatial disorientation and loss of memory are one of the first symptoms of Alzheimer's disease -- which destroys hippocampal neurons in its earliest stages -- these findings can further research efforts to understand the causes and potential cures for Alzheimer's and other neurodegenerative diseases. ""As an engineer, I find it particularly exciting that our interdisciplinary approach can be used to understand some of the most complex cognitive processing systems in the brain,"" adds Cowan.","For G > 1, the landmarks moved in the opposite direction, meaning that the rat ran a greater distance in the landmark frame than in the laboratory frame. Under gain-adjusted conditions, CA1 units (7.2 ± 5.8 (mean ± s.d.) units per session) tended to fire in normal, spatially specific place fields when the firing was plotted in the landmark frame, but not when plotted in the laboratory frame (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38508761472&p=1pl&v=1&x=rp-fvtU__EJpC0YUT2cLaw
10.1080/17543266.2014.923049,Computer_Science_easy_546,"Although the study is part of a project aimed at 'recording the motion of ballet dancers for both performance analysis and corrective coaching' explain the authors, the techniques used to produce the avatar could have applications within a range of disciplines, including performing arts, sports and fashion.","There are a number of tools within the software which can be used to attempt to 'clean up' the mesh such as: removing duplicate or null faces, merging close vertices, and flipping faces whose normals are opposite to all of its adjacent faces.","Led by two scientists at Manchester Metropolitan University, UK, the research illustrates the 'workflow for producing and animating a realistic virtual human ...using infrared depth sensing technology'. Although the study is part of a project aimed at 'recording the motion of ballet dancers for both performance analysis and corrective coaching' explain the authors, the techniques used to produce the avatar could have applications within a range of disciplines, including performing arts, sports and fashion. No doubt this exciting new study prepares the grounds for future investigations, and the Manchester team are already looking to take things further in the virtual environment and develop even more realistic and accurate avatars.","The scanner itself can be made mobile with a set-up and collapse time of only a few hours. There are a number of tools within the software which can be used to attempt to 'clean up' the mesh such as: removing duplicate or null faces, merging close vertices, and flipping faces whose normals are opposite to all of its adjacent faces. The software was found to be somewhat unreliable and had the tendency to crash when multiple operations were performed.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/07/140723110707.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.joi.2015.07.006,Computer_Science_easy_547,"Or perhaps the media is obsessed with driving us mad, curating each and every one--for our health, well-being, and financial worth.","Assuming that the rate of transition between states is X ti and X tj is exp −µd(Xt i ,Xt j ) , with µ being the scaling function, and, the probability of citing the paper is 1 when the peak in the number of citations is reached, the probability of citing the paper at time t is given by P Xt n−t0 (t).","They alter readers' lifestyle choices and drive consumer marketing trends. Or perhaps the media is obsessed with driving us mad, curating each and every one--for our health, well-being, and financial worth. It's no surprise then that researchers are also adjusting to today's volume of information, along with its short shelf-life.","The autocorrelation function has an exact solution for an ultrametric space defined by a hierarchical tree. Assuming that the rate of transition between states is X ti and X tj is exp −µd(Xt i ,Xt j ) , with µ being the scaling function, and, the probability of citing the paper is 1 when the peak in the number of citations is reached, the probability of citing the paper at time t is given by P Xt n−t0 (t). When the number of states is finite, such an autocorrelation function is exponential in nature, otherwise it follows a power law behavior .",[1],Computer_Science,train,1.0,news,http://www.thedailybeast.com/articles/2015/03/12/why-studies-have-driven-us-mad.html
10.1073/pnas.1718648115,Computer_Science_easy_550,"While the PNAS results provide a truly new and completely immersive piloting strategy with a focus on characterizing the relevant torso parameters, leaving the head, limbs, hands and feet free to perform other actions, their proof-of-concept system still requires body markers and external motion detectors in order to work.",1C ; see also SI Appendix).,"He adds, ""The approach significantly improves the teleoperation of robots with non-human mechanical attributes."" While the PNAS results provide a truly new and completely immersive piloting strategy with a focus on characterizing the relevant torso parameters, leaving the head, limbs, hands and feet free to perform other actions, their proof-of-concept system still requires body markers and external motion detectors in order to work. The next steps are to make the torso strategy completely wearable for piloting flying objects.","This was observed even if, with this reduced number of participants, there were no differences in terms of performances across the three strategies (P = 0.25). 1C ; see also SI Appendix). After completing the VR training and the free flight, the participants were able to steer the quadcopter along the defined path with an average percentage of validly crossed gates (PVC, 19) of 87.67 ± 9.88% (Movie S5).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34558158161&p=1pl&v=1&x=2k6qAj-rsU9AZsf1qXTJcg
10.1038/s41598-019-44221-3,Computer_Science_easy_551,"Researchers say it could support research involving mice, which play a crucial role in testing new therapies for human diseases.",Element separation is required where components of the call have different amplitudes.,"The computer tool can reveal valuable insights into rodents' communication patterns and is more reliable than existing methods, which rely on human interpretation. Researchers say it could support research involving mice, which play a crucial role in testing new therapies for human diseases. The new approach used machine learning techniques to make analysis faster, more reliable, and less subjective than human interpretation, the researchers say.","Specifically, we note the following characteristics for each call class: (1) Complex calls included one component containing two or more directional changes in frequency, each ≥6.25 kHz; (2) Two-component calls have two parts: a main call (flat or downward) with an additional shorter component at a different frequency towards the end; (3) Upward calls are a single harmonic that increases in frequency ≥12.5 kHz from beginning to end; (4) Downward calls follow the opposite trajectory to Upward calls, with a single harmonic that decreases in frequency ≥12.5 kHz from beginning to end; (5) Chevron calls resemble an 'inverted-U'; (6) Short calls are brief single harmonic calls ≤5 ms; Composite calls are formed by two harmonically independent components emitted simultaneously at different frequencies; (8) Frequency step calls include multiple instantaneous frequency harmonics appearing as a vertically discontinuous ""step"" on a spectrogram, but with no interruption in time; Flat calls are a single constant harmonic at a stable frequency (≤3 kHz change). Element separation is required where components of the call have different amplitudes. Adjustment of the hold threshold length is necessary where calls may have extended pauses between components (see Table 2 for settings for call types).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39980786851&p=1pl&v=1&x=Xhp9mNWsjiLGEVqmu08Yug
10.1038/s42256-018-0015-y,Computer_Science_easy_553,"The strict teacher

The Whetstone process, Aimone said, can be visualized as a class of talkative students, ruled by a newly strict teacher, who are tasked with identifying an object on the teacher's desk.","As GPUs and and other architectures increasingly pursue the ability to perform sparse computations efficiently, the resulting binary communication from the Whetstone method is well suited for such approaches.","It provides a standardized way to train traditional neural networks that are amenable for deployment on neuromorphic systems, which had previously been done in an ad hoc manner."" The strict teacher

The Whetstone process, Aimone said, can be visualized as a class of talkative students, ruled by a newly strict teacher, who are tasked with identifying an object on the teacher's desk. Both options increase the time and cost of commercial artificial intelligence products, lessen their security and privacy and make their acceptance less likely.","Not only does the Whetstone method offer a means to make use of emerging low power neuromorphic hardware, but it may be beneficial for other accelerators as well. As GPUs and and other architectures increasingly pursue the ability to perform sparse computations efficiently, the resulting binary communication from the Whetstone method is well suited for such approaches. For example, if an architecture can replace multiplications with signed addition the binarization of the communication by the Whestone method converts an ANN to a suitable representation.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38650188944&p=1pl&v=1&x=YFT-BMkwZFe4NLOD6XmlUQ
10.1145/3090090,Computer_Science_easy_554,"""The proof of concept we've developed is exciting today, and we think it could impact everyday devices in the future.""",11(a) shows that the signal strength of the received speech at the basestation decreases as the distance increases.,"Using off-the-shelf components on a printed circuit board, the team demonstrated that the prototype can perform basic phone functions -- transmitting speech and data and receiving user input via buttons. ""The proof of concept we've developed is exciting today, and we think it could impact everyday devices in the future."" ""And if every house has a Wi-Fi router in it, you could get battery-free cellphone coverage everywhere.""","For all practical purposes such as human hearing and interpretation, a PESQ ≥ 1 is considered to be sufficient . 11(a) shows that the signal strength of the received speech at the basestation decreases as the distance increases. At small distances, due to non-linearities in the JFET and the matching network, the received signal strength is slightly higher than the theory.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/EubzDUqdA0U/
10.1098/rspb.2014.1370,Computer_Science_easy_555,"Indeed, the study found no evidence for a Markovian process.","We found that the letter order in the English language is best modelled by a ZOMP, whereas previous work has indicated that an SOMP is a more appropriate model .","Using the Markov process to examine animal vocalization means that the sequence of variables -- in this case, the vocal elements -- is dependent only on a finite number of preceding vocal elements, making the process fairly random and far different from the complexity inherent in human language. Indeed, the study found no evidence for a Markovian process. The researchers used mathematical models to analyze the vocal sequences of chickadees, finches, bats, orangutans, killer whales, pilot whales and hyraxes, and found most of the vocal sequences were more consistent with statistical models that are more complex than Markov processes and more language-like.","The results of our test for robustness show that, with the exception of the pilot whale data, wherever a clear best-fit model is indicated, the chosen model is consistent between larger sub-sample sizes, and we believe that this is an indication of reliability of our conclusions. We found that the letter order in the English language is best modelled by a ZOMP, whereas previous work has indicated that an SOMP is a more appropriate model . However, English is clearly neither a ZOMP nor an FOMP, and so the resemblance of a corpus of English letters to one or the other may be more dependent on the metric used to assess similarity, rather than the underlying stochastic processes.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2014/08/140819200209.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1073/pnas.1701352114,Computer_Science_easy_557,"So, it's vital that we continue to further our understanding of this part of the brain,"" he says.",; Fig.,"So, it's vital that we continue to further our understanding of this part of the brain,"" he says. By measuring their brain activity, the researchers identified three previously unknown traits of the system:

Humans rescale their internal coordinate system according to the size of each new environment. This flexibility differs from rodents' rigid map that has a constant grid scale and empowers humans to navigate diverse places.","The average grid period of PGCs determined in the small environment showed a significant expansion when probed in the larger environments [Wilcoxon signed rank test, P (n = = 1.2937e −04 ; Fig. No significant difference in grid periods between the large environments (LV and LX) was found owing to the similarity of their dimensions [Wilcoxon signed rank test, P (n = 5) = 0.3125; Fig.",[1],Computer_Science,train,1.0,news,http://www.futurity.org/navigation-scaling-mechanism-1403342-2/
10.1098/rsif.2013.1211,Computer_Science_easy_558,But that will not tell you how to think through the problem so that you can generalize the solution to a related problem.,"What counts as evidence for process contagion is a significant interaction between question and topology, showing that the increase in performance in the network group is greater than the increase in performance in the Baseline group.","And that works short term. But that will not tell you how to think through the problem so that you can generalize the solution to a related problem. You become dependent to your social network.""","Processing contagion should improve performance from one question to the next, in addition to improving performance from one trial to the next. What counts as evidence for process contagion is a significant interaction between question and topology, showing that the increase in performance in the network group is greater than the increase in performance in the Baseline group. We detected no such significant interaction for any topology, all z , 1.05, all p .",[1],Computer_Science,train,1.0,news,http://www.technology.org/2014/02/24/oregon-study-imitation-flattery-limits-analytical-thinking/
10.1145/2675133.2675290,Computer_Science_easy_559,"Among other critiques, Morozov voiced two important questions in a larger debate over the value of collective action online.","Whereas .8% of individuals who did not Table 1 : Adoption Probability for Exposed Users, by Age and Gender list any education level adopted, 1.0% of high school graduates did so, the proportion increasing to 2.4% for users with college degrees and to 4.6% for users with graduate educations.","Experts downplayed the importance of such actions; Global Voices Iran editor Fred Petrossian argued that talk of a Twitter revolution ""reveals more about Western fantasies for new media than the reality in Iran."" Among other critiques, Morozov voiced two important questions in a larger debate over the value of collective action online. First, he argued that social-media solidarity has an unknown effect toward political change, perhaps even siphoning energy away from more effective action.","Individuals who listed higher education were also more likely to display the equal sign picture than those individuals not listing education. Whereas .8% of individuals who did not Table 1 : Adoption Probability for Exposed Users, by Age and Gender list any education level adopted, 1.0% of high school graduates did so, the proportion increasing to 2.4% for users with college degrees and to 4.6% for users with graduate educations. Individuals listing themselves as ""Interested in"" persons of the same gender as themselves were 8 times more likely (11.0%) to adopt the equal sign than individuals whose ""Interested in"" field indicated persons of the opposite gender (1.4%).",[1],Computer_Science,train,1.0,news,http://www.theatlantic.com/technology/archive/2015/06/were-all-those-rainbow-profile-photos-another-facebook-experiment/397088/
10.1145/2567948.2576948,Computer_Science_easy_561,"If you try to sneak one past the Group it will likely be caught by an ""anti-bot bot."")","Concluding, we have contributed a useful toolset and performed a preliminary global study with interesting insights that is the first in a series of future studies and applications by us and others.","(To run on Wikipedia, they must pass through a Bot Approval Group. If you try to sneak one past the Group it will likely be caught by an ""anti-bot bot."") When he had to move out of his apartment unexpectedly, he found himself without a place to connect the computer to the Internet.","At the end of the observation, from all 287 Wikipedias and Wikidata, exactly 260 (∼ 90.3%) were edited. Our toolset being publicly available, interested parties can run longer analyses at will. Concluding, we have contributed a useful toolset and performed a preliminary global study with interesting insights that is the first in a series of future studies and applications by us and others.",[1],Computer_Science,train,1.0,news,http://www.newsweek.com/wikipedia-edited-bots-thats-good-thing-230234
10.1038/s41928-018-0072-6,Computer_Science_easy_562,"This new telemetry approach will make possible the long-sought goal of successfully detecting tiny physical or chemical actuation from contactless microsensors.""","If the coupling strength exceeds a certain threshold, the system can reach equilibrium, since the energy in the active tank can flow fast enough into the passive one to compensate its power dissipation.","The researchers were able to show this phenomenon in a telemetric sensor system based on a radio-frequency electronic circuit, which exhibited drastically improved resolution and sensitivity compared to conventional sensors. This new approach may allow researchers to overcome the current challenges in deploying ubiquitous networks of long-lasting, unobtrusive microsensors to monitor large areas. This new telemetry approach will make possible the long-sought goal of successfully detecting tiny physical or chemical actuation from contactless microsensors.""","This can be explained by the fact that, if the coupling strength is weak, the energy in the active -RLC tank cannot flow fast enough into the passive RLC tank to compensate for the absorption, thereby resulting in a non-equilibrium system with complex eigenfrequencies. If the coupling strength exceeds a certain threshold, the system can reach equilibrium, since the energy in the active tank can flow fast enough into the passive one to compensate its power dissipation. 3a , we observe that at higher  , the threshold of  for the phase transition ( EP  ) can be reduced.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34048776858&p=1pl&v=1&x=KPOFS4udrKHxZ9cLHCtjtg
10.1038/srep01360,Computer_Science_easy_563,The answer gives pause for thought.,"Formally, the mutual information, I(X, Y), between variables X and Y, equals H(X) 1 H(Y) -H(X, Y), where H(X) is the information (entropy) in X, and H(X, Y) is the joint entropy of X and Y.","The answer gives pause for thought. It turns out that in these circumstances, the way people modify their answer follows a simple and linear mathematical rule. That's a surprise for two reasons.","how much knowing one of these variables reduces uncertainty about the other 21 . Formally, the mutual information, I(X, Y), between variables X and Y, equals H(X) 1 H(Y) -H(X, Y), where H(X) is the information (entropy) in X, and H(X, Y) is the joint entropy of X and Y. If X and Y are independent then H(X, Y) 5 H(X) 1 H(Y), and thus the mutual information, I(X, Y), equals 0.",[1],Computer_Science,train,1.0,news,http://www.technologyreview.com/view/511301/decisions-and-the-influence-of-others?nopaging=1
10.1016/j.neuroimage.2015.04.009,Computer_Science_easy_564,"""One in five people with mild cognitive impairment go on to develop Alzheimer's and this will identify the connections that break down at the early phase of the disease,"" he said.","The SMA and rolandic areas are activated during the movements essential for speech production , thereby suggesting this subnetwork is specialised for sensorimotor integration.","Mr Perry said the next step would be to use the same methods to map the connectome of those with mild cognitive impairment. ""One in five people with mild cognitive impairment go on to develop Alzheimer's and this will identify the connections that break down at the early phase of the disease,"" he said. ""We would then be able to predict with greater accuracy if someone is at increased risk of Alzheimer's, and could develop new approaches to treatments.""","The first bundle of the second left-lateralized subnetwork interconnects parietal (angular and Geschwind's area) regions with temporal (middle and superior) areas, and the second is consistent with arcuate fasciculus circuits connecting Wernicke's to Broca's area. The SMA and rolandic areas are activated during the movements essential for speech production , thereby suggesting this subnetwork is specialised for sensorimotor integration. Nevertheless, these strong leftward lateralizations are surprising given decreased functional specialisation of both prefrontal and language networks is typically reported with age Cabeza et al., 2002; Davis et al., 2012) .",[1],Computer_Science,train,1.0,news,http://www.healthcanal.com/brain-nerves/63595-scientists-map-healthy-elderly-brain.html
10.1098/rspb.2013.0077,Computer_Science_easy_566,The researchers are currently attempting to get regulatory approval to begin clinical trials in the United States and Europe as well.,"However, the remaining visual pathway, from the bipolar cells onwards, remains largely functional.","""The results published today show definite promise to one day restore functional vision to patients with advanced-stage retinitis pigmentosa."" Clinical studies of the implant are also taking place in England and Hong Kong. The researchers are currently attempting to get regulatory approval to begin clinical trials in the United States and Europe as well.","These data show that subretinal implants can restore visual functions that are useful for daily life. However, the remaining visual pathway, from the bipolar cells onwards, remains largely functional. However, complicated goggles with high-luminance laser stimulators are necessary for providing sufficiently bright images to drive such passive light sensors.",[1],Computer_Science,train,1.0,news,http://www.livescience.com/27252-eye-implant-restores-vision-blind.html
10.1038/s41562-017-0273-4,Computer_Science_easy_567,While most people's estimates were too high or too low -- falling an average of 37 lbs.,But the evidence is not exhaustive and does not necessarily imply positive evidence for the hypothesis that our crowd shared arguments during deliberation.,"While most people's estimates were too high or too low -- falling an average of 37 lbs. -- the median of everyone's guess was off by only 9 lbs., or less than 1 percent of the true weight of the ox. This example illustrates what has come to be known as the ""wisdom of crowds"" effect.","The above analysis definitively rejects the more simplified models of consensus. But the evidence is not exhaustive and does not necessarily imply positive evidence for the hypothesis that our crowd shared arguments during deliberation. The procedure with highest endorsement was ""We shared arguments and reasoned together"" (mean rating ± s.e.m across all questions: 7.7 ± 0.2, mode rating: 10; z > 7.05, P < 10 −12 for all comparisons, Table 1 ).",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33546472265&p=1pl&v=1&x=m0YzH3GvqBEVW56wBmptdA
10.1038/nature13457,Computer_Science_easy_569,"Indeed, ""For the zero-knowledge property to be conserved, neither the signal nor the noise may carry information,"" the authors write.",They achieve the paradoxical goal of allowing one to prove that a statement is true without revealing why it is true.,"Even statistical noise -- or random variation in neutron measurement -- would convey no data. Indeed, ""For the zero-knowledge property to be conserved, neither the signal nor the noise may carry information,"" the authors write. A necessary future step is to assess this proposition fully, and to develop and review a concept of operations in detail to determine actual viability and information sensitivity.","Such agreements would require new verification approaches, including inspections of individual nuclear warheads in storage and warheads entering the dismantlement queue. They achieve the paradoxical goal of allowing one to prove that a statement is true without revealing why it is true. Such proofs are extremely useful for many digital applications, including privacy-preserving data mining, electronic voting and online auctions .",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5HBLrnzMT4w/
10.1126/scirobotics.aaw6736,Computer_Science_easy_570,Applications of the Maryland research could extend far beyond robotics.,3) Sequences can be interpreted as a succession of ordered pairs.,"""Our hyperdimensional framework can address each of these goals."" Applications of the Maryland research could extend far beyond robotics. Hyperdimensional computing could provide a faster and more efficient alternative model to the iterative neural net and deep learning AI methods currently used in computing applications such as data mining, visual recognition and translating images to text.","Given c and knowing P and one of the pairs, the other can be found. 3) Sequences can be interpreted as a succession of ordered pairs. Thus, a sequence C 1 , C 2 ,…C n is equivalent to",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39233550184&p=1pl&v=1&x=fAcjMEn_4kCs-HjzhjlwVQ
10.1126/science.aaq1118,Computer_Science_easy_571,"""Take for example geology, where students have to learn to differentiate between rocks or geologic formations that may have a highly similar appearance,"" said Sims.","The assumed loss function, Lðx;xÞ, in this example is squared error.","The finding, which was published in the journal Science, is an outgrowth of National Science Foundation-supported research into improving pedagogy in STEM fields, which often rely heavily on perceptual abilities and perceptual expertise, said Chris Sims, a Rensselaer Polytechnic Institute assistant professor of cognitive science. ""Take for example geology, where students have to learn to differentiate between rocks or geologic formations that may have a highly similar appearance,"" said Sims. But understanding how the brain works can help us build better classroom training exercises that teach those abilities more efficiently.""","This exponential generalization pattern has indeed proved to be near-universal, and the success of the empirical law has been impressive, accounting for data spanning a wide range of domains, sensory modalities, and across multiple species (6-8). The assumed loss function, Lðx;xÞ, in this example is squared error. (B) The precision and bias of the perceptual channel depend on the available capacity; higher channel capacity enables lower perceptual error and hence lower expected cost.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=37159648169&p=1pl&v=1&x=A_GaRtVE14MsUmj_yYXrbg
10.1073/pnas.1221839110,Computer_Science_easy_572,The researchers analyzed a data collection of 3.7 million nodes and found that connections between Gore's 1976 filing and other patents formed 39 distinct communities in the database.,"These assumptions capture that the connections between nodes can be explained by their memberships in multiple communities, even if we do not know where those communities lie.","Blei likens it to finding your way from New York to Los Angeles by stopping random people and asking for directions -- if you ask enough people, you will eventually find your way. advertisement

""With noisy measurements, you can still make good progress by doing it many times as long as the average gives you the correct result,"" he said. The researchers analyzed a data collection of 3.7 million nodes and found that connections between Gore's 1976 filing and other patents formed 39 distinct communities in the database.","If these indicators point to the same community, then it connects nodes i and j with high probability; otherwise, they are likely to be unconnected. These assumptions capture that the connections between nodes can be explained by their memberships in multiple communities, even if we do not know where those communities lie. (In the full model, they will also have a small probability of being connected when the indicators are different, but this simplified version gives the intuition.)",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/12/131202121546.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1216338110,Computer_Science_easy_573,"In addition, passive participants, who don't recruit others but may help with the task if they were to come across a balloon, play an important role.","Mobilization requires highly connected, highly active individuals to be motivated to propagate the message to a large number of friends, and to mobilize people in distant locations, overcoming the local trapping of diffusion in highly dense areas.","Small world

Rallying thousands of people requires leaders who respond rapidly, have many connections and forward information much faster than the average person, the researchers found. In addition, passive participants, who don't recruit others but may help with the task if they were to come across a balloon, play an important role. Being successful also relied on the ""small world"" phenomenon.","Our results demonstrate, surprisingly, that the DARPA Network Challenge outcome is plausible, and thus it is not simply a fluke that can only be explained by the role of mass media. Mobilization requires highly connected, highly active individuals to be motivated to propagate the message to a large number of friends, and to mobilize people in distant locations, overcoming the local trapping of diffusion in highly dense areas. Moreover, even under highly favorable conditions, the risk of mobilization failure remains significant.",[1],Computer_Science,train,1.0,news,http://www.livescience.com/28341-social-media-helps-mobilize-society.html
10.1038/srep41870,Computer_Science_easy_574,"This study suggests that the practice of avoiding moral assessments can be the best policy when assessing those who refuse to help (""punish"") wrongdoers.",This leads to the second term in the sum for g X .,"Indeed, under the Staying rule, good cooperators can proliferate no matter how many freeloaders surround them, so long as the error rate is sufficiently small. This study suggests that the practice of avoiding moral assessments can be the best policy when assessing those who refuse to help (""punish"") wrongdoers. ""Reputation-seeking punishment, described as I'll punish your bad behavior to make me look good,' may not be the best way to subvert a population of freeloaders,"" says Sasaki.",Stern-judging assigns a good image to those who refuse help for a bad recipient and a bad image to those who give help for a bad recipient. This leads to the second term in the sum for g X . This conditional probability is (1 -e 1 )e 2 + e 1 (1 -e 2 ) = 1 -ε.,[1],Computer_Science,train,1.0,news,https://www.sciencedaily.com/releases/2017/02/170207105331.htm
10.1145/3219819.3219896,Computer_Science_easy_575,"Some basic things were known about the lead-pipe distribution: The pipes were most likely to be found in postwar homes, built when Flint experienced major expansions, and least likely to be found in newer homes.",IWAL more effectively optimizes HVI hit rate.,"That's what started the problem. The decay of infrastructure built decades ago is not only in the metal, but in the data cataloging that lets the city's government and residents understand the state of the water system. Some basic things were known about the lead-pipe distribution: The pipes were most likely to be found in postwar homes, built when Flint experienced major expansions, and least likely to be found in newer homes.",egreedy(0) tends to over-inspect whereas egreedy (1) is too conservative. IWAL more effectively optimizes HVI hit rate. activities different than Flint FAST Start.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=38146229343&p=1pl&v=1&x=7VTy1-8iHCQ3LCaXUuskcQ
10.1126/scirobotics.aat1893,Computer_Science_easy_576,The UC team says their eel is likely the softest underwater robot yet developed.,By inserting Eq.,Their eel-like creation could one day become a preferred way to study marine life since it's not as big and loud as the motor-driven remote-operated underwater vehicles used today. The UC team says their eel is likely the softest underwater robot yet developed. Softer robots are less likely to damage underwater structures like coral reefs or the animals themselves if they accidentally come into contact with them.,"1 to be the leadingorder expression for the longitudinal strain in the extreme tensile fiber of the beam, we find, after dropping a constant of 3/2, that By inserting Eq. 3 and rearranging, we find the leading-order functional dependence of the curvature to be This result suggests that the curvature is proportional to the square of the applied voltage and inversely proportional to the thickness of the actuator to the third power.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33888314821&p=1pl&v=1&x=BSLp9FW0F5eXwWccmy_cSA
10.1007/978-3-319-67256-4_3,Computer_Science_easy_578,"Depending on their syntacic complexity, two sentences of similar lengths will place widely variable demands on their readers and reflect far different commands of writerly sophistication.",VKs support team confirmed to us that the data downloaded via their API may be used for research purposes.,"Still more troubling, neither study takes into account the role played by the complexity of sentence structure, which place the most intense demands on readers and writers alike. Depending on their syntacic complexity, two sentences of similar lengths will place widely variable demands on their readers and reflect far different commands of writerly sophistication. With only 7% of its words unfamiliar to a typical fourth grader, the first example nets a Dale-Chall readability score that puts it within the grasp of fifth to sixth graders, or at about the level of most mass circulation US newspapers.","In particular, it is possible to download user profiles from certain educational institutions and within selected age ranges. VKs support team confirmed to us that the data downloaded via their API may be used for research purposes. The relationship between time of site adoption and complexity growth in Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34664685793&p=1pl&v=1&x=tPMecHWKMWfnf127u3sgDQ
10.1002/asi.23005,Computer_Science_easy_579,That portion grew to 47% by 2013.,The quality of papers and competence of researchers should be evaluated independently of the journal in which the work appeared for two reasons.,"In 1995, only 27% of citations pointed to articles published in nonelite journals. That portion grew to 47% by 2013. And the nonelite journals published an increasing share of the most highly cited papers within each field as well, growing from 14% to 24%.","Finally, advancement, recruitment and grant-evaluation committees, administrators and other evaluators should heed these results. The quality of papers and competence of researchers should be evaluated independently of the journal in which the work appeared for two reasons. Second, even if this journal hierarchy were valid, the hierarchy is not fixed.",[1],Computer_Science,train,1.0,news,http://news.sciencemag.org/scientific-community/2014/10/uprising-less-prestigious-journals-publishing-greater-share-high-impact
10.1145/3025453.3025909,Computer_Science_easy_580,De Choudhury also thinks that the wider variety of backgrounds at large public schools likely lends itself to a more robust sharing of stress and anxiety issues.,"In summary, we observe that our transfer learning based classifier is able to robustly detect and characterize MH expressions in Reddit posts with high accuracy.","Therefore, the stresses of paying for college or going into debt aren't as great. De Choudhury also thinks that the wider variety of backgrounds at large public schools likely lends itself to a more robust sharing of stress and anxiety issues. ""As for more posts about mental health at universities with more females, I don't think it's necessarily because women have more anxiety,"" De Choudhury said.","On the other hand, the predictor features with large negative coefficients span a diverse range of topics, ranging from events and experiences ('christmas"", 'pregnant""), lifestyle (""workout"", ""gym""), sports (""game""), community participation and usage practices (""lpt request"", ""want know"", ""curious""), to Reddit specific topics (""reddit"", redditors"", ""edit""). In summary, we observe that our transfer learning based classifier is able to robustly detect and characterize MH expressions in Reddit posts with high accuracy. The final agreement was found to be high (Cohen's  = .83).",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/who-has-better-mental-health-public-or-private-college-students/
10.1038/s41598-018-28527-2,Computer_Science_easy_581,"When neurons aren't signaling at this ratio, there is a breakdown in information flow efficiency between cells.",We observed similar single neuron reconstructions for all the cells in our data set.,"Long, short, straight and curvy axons all had a refraction ratio approaching one. When neurons aren't signaling at this ratio, there is a breakdown in information flow efficiency between cells. ""We think that may be the case for individual neurons, as well as networks of neurons.""","The figure highlights the difference between the geodesic (shortest) path distance in the minimized network, relative to the actual morphological paths of the axon arbor (Fig. We observed similar single neuron reconstructions for all the cells in our data set. We obtained an average conduction velocity of 0.39 ± 0.16 m/s (Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34527865337&p=1pl&v=1&x=cJYdHH3jeacVdPCuGGpQUg
10.1089/soro.2018.0115,Computer_Science_easy_582,The shower hose went wild as if it had a life when I inadvertently turned on the faucet at maximum.,The latter is relatively slow because the driving unit is caught on the corner when getting over the wall.,"This is the world's first achievement in developing soft and flexible robot that is capable of free movement on a wall. The shower hose went wild as if it had a life when I inadvertently turned on the faucet at maximum. Robot with flexible body structure is not only highly adaptable to environment, but also highly secure against collision.","The wallto-ground transition and the thin wall transition take *18 and 86 s, respectively. The latter is relatively slow because the driving unit is caught on the corner when getting over the wall. The shape parameter values are changed by changing only the element torsional stiffness k and element mass m as with Figure 10 .",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39212819301&p=1pl&v=1&x=ZS6g1vtdTdSU3RbPyZAPVA
10.1186/2051-3933-1-3,Computer_Science_easy_583,"Tasks that used to take graduate students countless hours now require only a click of the mouse, Kays said.","For instance, for categorical data, such as land-use type, only the nearest neighbor interpolation can be applied, whereas for continuousnumeric data types either a nearest neighbor, bilinear (in regular grids), or inverse weighted distance interpolation can be selected based on the resolution of data .","Scientists learned that the birds' chosen paths took them to preferred areas on the Peruvian coast where they could forage. In addition to allowing scientists to work with layers of information, Env-DATA simplifies the tedious work of data manipulation. Tasks that used to take graduate students countless hours now require only a click of the mouse, Kays said.","The user can apply different methods of interpolation to space and to time. For instance, for categorical data, such as land-use type, only the nearest neighbor interpolation can be applied, whereas for continuousnumeric data types either a nearest neighbor, bilinear (in regular grids), or inverse weighted distance interpolation can be selected based on the resolution of data . Metadata for the output is uniform across different annotation requests and movement data types, which simplifies linking the output with further analysis tools.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130703160615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41598-018-30619-y,Computer_Science_easy_584,"""Some future version of our system would be especially useful in rapid decision-making applications, like autonomous vehicles,"" Wetzstein says.","Since the actual phase mask had only 16 discrete heights instead of the continuous heights allowed in the phase mask optimization, the PSF produced by the physical phase mask, though very similar, did not exactly match the target PSF.","While their current prototype, arranged on a lab bench, isn't exactly small, the researchers say their system can one day shrink to fit in a handheld video camera or an aerial drone. In both simulations and real-world experiments, the team used the system to successfully identify airplanes, automobiles, cats, dogs, and more within natural image settings. ""Some future version of our system would be especially useful in rapid decision-making applications, like autonomous vehicles,"" Wetzstein says.","The prototype test accuracy falls slightly below the simulated opt-conv test accuracy of 51.0%, likely due to hardware imperfections unaccounted for in simulation. Since the actual phase mask had only 16 discrete heights instead of the continuous heights allowed in the phase mask optimization, the PSF produced by the physical phase mask, though very similar, did not exactly match the target PSF. In addition, the boundaries of the convolved sub-images may not have precisely aligned with the sensor pixels due to the different pixel sizes of the DMD and camera sensor, resulting in alignment imperfections when subtracting kernels to yield the pseudonegative sub-images.",[1],Computer_Science,train,1.0,news,https://www.futurity.org/artificial-intelligence-image-recognition-camera-1842282/
10.1186/s12911-016-0327-y,Computer_Science_easy_585,Participants tended to set their own standards and rules for social media health communications.,It's not a lot of time.,"The 17 physicians involved in the study were:

35 percent female

76 percent pediatricians

76 percent bloggers

3. Participants tended to set their own standards and rules for social media health communications. Physician-participants expressed uncertainty about social media boundaries or strategy.","One participant described: ""I would say, the nice thing about social media is that you can do it in between things. It's not a lot of time. While some physicians postulated that their posts on social media may increase clinic efficiency by decreasing unnecessary patient calls and visits, others believed that it decreased efficiency by distracting providers from direct patient care.",[1],Computer_Science,train,1.0,news,http://www.beckersspine.com/orthopedic-spine-practices-improving-profits/item/35544-should-physicians-use-social-media-to-distribute-health-information-7-things-to-know.html
10.1016/j.cub.2013.11.014,Computer_Science_easy_588,"Such routine publication of datasets might open the door to new kinds of research projects, with shared observations quickly stitched together into cohesive form by multiple groups, similar to how a computer program is written by collaborative teams using multiple open components today.","Our proportions for 10-year-old e-mails are lower, with only 51% of e-mails from 2003 returning an error.","One might be to turn data itself into a measurable product that can help advance scientists' careers, bringing the same rewards as publishing results in a journal. Such routine publication of datasets might open the door to new kinds of research projects, with shared observations quickly stitched together into cohesive form by multiple groups, similar to how a computer program is written by collaborative teams using multiple open components today. The more forks your software has, and thus the most uses, the better rewarded you are as a software developer in terms of career prospects and salary.","reported a steep decline with age in the proportion of functioning e-mails from papers published between 1995 and 2004, such that 84% of their 10-year-old e-mails returned an error message. Our proportions for 10-year-old e-mails are lower, with only 51% of e-mails from 2003 returning an error. It may be that e-mail addresses are becoming more stable through time, although this clearly requires additional study.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=32710794585&p=1pl&v=1&x=wpOmqL2FGXnFiRFWSPiBZw
10.3758/s13428-015-0567-2,Computer_Science_easy_589,"They can help distinguish between different theories of perception, memory, decision-making and social cognition.",The R values were less than 1.025 for all parameters.,"In psychology research, response times may be used to discover which mental operations are more difficult than others, or to measure how uncertain people are about a decision. They can help distinguish between different theories of perception, memory, decision-making and social cognition. Measuring response times is only one of many applications of jsPsych.","These describe the overall effects of the software environment across all subjects. The R values were less than 1.025 for all parameters. The full model specification, in JAGS format, and the complete MCMC sample, in .Rdata format, are available online at http://hdl.handle.net/2022/19253.",[1],Computer_Science,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150430155057.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.3389/frobt.2017.00074,Computer_Science_easy_590,"This differentiates Winfield's approach from machine learning, in which an AI system may use, for example, an artificial neural network that can train itself to carry out desired actions in a manner that satisfies the expectations of its users.","From the mismatch between the trajectories and the arena walls, it is obvious that the calibration of the motion capturing system placed its coordinate system rotated by about 3° and also slightly offset.","Winfield thinks enabling robots to do this will help them infer the goals and desires of agents around them--like realizing that the running couple really wanted to get that elevator. This differentiates Winfield's approach from machine learning, in which an AI system may use, for example, an artificial neural network that can train itself to carry out desired actions in a manner that satisfies the expectations of its users. In other words, a robot equipped with the system can answer simple ""what if"" questions about potential actions.","There is a reality gap between every simulator and the physical object it represents. From the mismatch between the trajectories and the arena walls, it is obvious that the calibration of the motion capturing system placed its coordinate system rotated by about 3° and also slightly offset. This is due to the calibration process of the motion capturing system using a manually placed ground plate with markers to establish the motion capturing coordinate system.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34838941313&p=1pl&v=1&x=oSwDUVnD7YX6fgJSx7-0Tw
10.1016/j.neuroimage.2013.01.071,Computer_Science_easy_591,"Once you have the foothold, you can keep pulling and pulling and the whole picture has unraveled and you can understand what's going on.""",Various searchlight radii were investigated and yielded qualitatively similar results for radii≥ 5 mm.,"It's like taking a thread from a tapestry that you can hold onto and pull. Once you have the foothold, you can keep pulling and pulling and the whole picture has unraveled and you can understand what's going on."" The research will clear the way for further study into the brain and genetics.","Only activations with at least 25% probability of being in gray matter were retained (based on the Talairach atlas provided in the AFNI package; specifically, the TT_caez_gw_18 mask). Various searchlight radii were investigated and yielded qualitatively similar results for radii≥ 5 mm. This correction is suggested if n > S; thus, voxels with fewer than 21 observations were excluded from further analysis.",[1],Computer_Science,train,1.0,news,http://www.healthcanal.com/genetics-birth-defects/39630-groundbreaking-brain-imaging-research-may-change-treatment-for-down-syndrome-other-genetic-disorders.html
10.1073/pnas.1701590114,Computer_Science_easy_593,And you no longer have to remember it.,1B) showed that drops like those following constituent unifying words in the sentence task did not occur.,"Once a complete phrase emerges, ""you can merge all of those memories together into one phrase. And you no longer have to remember it. So, the activity drops off.""","In the word-list task, with high working-memory demands but no possibility of constituent-structure building, trial-by-trial evoked responses in aSTS (Fig. 1B) showed that drops like those following constituent unifying words in the sentence task did not occur. Rather, there was sustained activity in the aSTS up to about the fifth word presentation during the word list task (SI Appendix, Fig.",[1],Computer_Science,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/S2UH5DG6jYo/
10.1063/1.5039641,Computer_Science_easy_594,"""We've really done two things here,"" Chiles said.",This routing manifold accomplishes the routing between two layers of a feed-forward neural network with 10 neurons per layer and all-to-all connectivity.,"The output was highly uniform, with low error rates, confirming precise power distribution. ""We've really done two things here,"" Chiles said. Both advances are crucial as we begin to scale up to massive optoelectronic neural systems.""",The stacking of waveguides allows for dense integration with lowloss and low-crosstalk waveguide crossings. This routing manifold accomplishes the routing between two layers of a feed-forward neural network with 10 neurons per layer and all-to-all connectivity. The routing network can be pruned to achieve any subset of connections.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34656803579&p=1pl&v=1&x=AvLls5JeV-dy_nudM1dptg
10.1126/sciadv.aat2731,Computer_Science_easy_596,"For something as complicated as this, it would be extremely difficult to write such a program.","However, closer inspection of the helicene time distributions suggest that VR does afford some advantage: the median time required to change molecular screw-sense in VR is 30-40% less than the median time required on a touchscreen.","A big reason I find this work so fascinating is because it requires unifying the state-of-the-art in technology with aesthetics, design and psychology."" For something as complicated as this, it would be extremely difficult to write such a program. Using VR, we can explore these knotted structures, tying and untying them easily!""","Essentially, the 2d limitations of the mouse and touchscreen constrain the user to carrying out a motion which is well suited to inducing changes in molecular screw-sense. However, closer inspection of the helicene time distributions suggest that VR does afford some advantage: the median time required to change molecular screw-sense in VR is 30-40% less than the median time required on a touchscreen. Significantly, every task considered in Figs 2 and 3 shows a median VR time which (i) is always faster than the mean, and (ii) lies outside the standard error limits.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34452341870&p=1pl&v=1&x=nkjGlXHfOJXPScyVT5YBVA
10.1111/jcc4.12054,Computer_Science_easy_597,"Whether those players are outliers or the norm, and what percentage of their gaming time is spent at social events versus in the privacy of their own homes, seem to be matters for future study.","While this would seem to make it easier to solicit their involvement, it often felt as if we were singling them out (of course we were), which seemed to elicit their discomfort on several occasions, regardless of whether they were approached by male or female researchers.","Of course, Dr. Taylor and his team were observing gamers in social settings, not in their basements, and they don't explain how they chose the gamers they surveyed more closely, but it's possible that -- intentionally or not -- they surveyed people who were simply more social and willing to be, you know, surveyed. Still, at the very least the researchers established that, at least in social gaming settings outside the confines of our dark basements, players are socially engaged, and on several levels. Whether those players are outliers or the norm, and what percentage of their gaming time is spent at social events versus in the privacy of their own homes, seem to be matters for future study.","Both in terms of their physical and virtual positioning, these women were marginal to their group's activities. While this would seem to make it easier to solicit their involvement, it often felt as if we were singling them out (of course we were), which seemed to elicit their discomfort on several occasions, regardless of whether they were approached by male or female researchers. These examples illustrate the interconnected assemblages of participants, researchers, games and gaming platforms, and the spatial arrangement of public gaming sites, through which we constructed a demographic look of online play in public sites.",[1],Computer_Science,train,1.0,news,http://www.cnet.com/news/study-finds-online-gamers-arent-anti-social-basement-dwellers/
10.1073/pnas.1804420115,Computer_Science_easy_599,"The root of the problem can be traced to the small number of parameters, such as particle size, brightness and shape, used by current software to identify the full range of particles present in any video.","That is, P n is a connected set and p ijk ≥ 0.5 for all p ijk ∈ P n .","""We got tired of the bottleneck."" The root of the problem can be traced to the small number of parameters, such as particle size, brightness and shape, used by current software to identify the full range of particles present in any video. As it turns out, they could and used their discovery to launch Chapel Hill-based AI Tracking Solutions, which is seeking to commercialize the new technology.","Tensorflow can be easily adapted to use multiple cores of a CPU or GPU, depending on available hardware. That is, P n is a connected set and p ijk ≥ 0.5 for all p ijk ∈ P n . Note that there are alternative particle localization methods that may increase accuracy.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34894829516&p=1pl&v=1&x=9aVV4K0njKiVwC37ZM5icA
10.1098/rspb.2018.0594,Computer_Science_easy_600,"""This is unprecedented in the animal kingdom,"" she points out.","However, overall the median maximum cross-correlation coefficient was not significantly different from 0 for yaw and torsion rotation, yaw and pitch rotations or pitch and torsion rotation (Wilcoxon signed-rank test, n ¼ 17, V ¼ 117, p .","But mantis shrimp are still able to ""reliably and accurately follow the motion of a pattern that is moving sideways"" no matter which position they roll their eyes or how fast they do it, explains the news release. The results revealed that ""rolling has absolutely no effect on their perception of space at all: up is still up, even when their eyes have rolled completely sideways,"" states Daly. ""This is unprecedented in the animal kingdom,"" she points out.","The median torsional pose relative to the horizontal was 67.34 + 0.128 (median + 95% CI, n ¼ 17) and the median pitch pose relative to the horizontal was 16.64 + 0.088 (median + 95% CI, n ¼ 17). However, overall the median maximum cross-correlation coefficient was not significantly different from 0 for yaw and torsion rotation, yaw and pitch rotations or pitch and torsion rotation (Wilcoxon signed-rank test, n ¼ 17, V ¼ 117, p . These findings demonstrate that stomatopods are able to independently rotate their eyes in the three degrees of rotational freedom, but that these rotations can become coupled in some instances, such as the yaw and torsion rotation during optokinesis shown in figure 2a,b.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33947918772&p=1pl&v=1&x=akKeJRPiyJA9kgKuJ2cSKg
10.7717/peerj.313,Computer_Science_easy_601,The site lasted just six months before Brookes was outed and the site was shut down under a bombardment of legal threats.,"Most cases involved data within a single paper, but in a small percentage of cases data appeared to be re-used between papers originating from the same laboratory group.","The site lasted just six months before Brookes was outed and the site was shut down under a bombardment of legal threats. Because of a high volume of submissions, Brookes still had 223 articles whose alleged problems he never had time to publish--not far from the 274 the site actually had managed to review. This gave him a unique opportunity, he realized.","The majority (∼75%) of problems encountered were apparent inconsistencies in western blotting data (undisclosed splicing, or apparent re-use of bands or blots to represent different experimental conditions), with the remainder relating to apparent re-use of light/fluorescent/electron microscopy images, apparent re-use of text, and apparent re-use of FACS histograms to represent different experimental conditions. Most cases involved data within a single paper, but in a small percentage of cases data appeared to be re-used between papers originating from the same laboratory group. Due to the sensitive nature of its content, the full data set for this study comprising the list of publications, including those for which no action was taken, cannot be provided.",[1],Computer_Science,train,1.0,news,http://www.psmag.com/navigation/nature-and-technology/fix-bad-science-78308/
10.1126/scirobotics.aas8713,Computer_Science_easy_602,"Contrary to expectations, they found that the thin spiral inspired by nature is not the optimal shape, but rather a thick arc with twisted ends.",This condition turns the second equation in Eq.,"As a result, they can now calculate the maximum possible speed of random clusters, and the optimal shape for these tiny swimmers. Contrary to expectations, they found that the thin spiral inspired by nature is not the optimal shape, but rather a thick arc with twisted ends. This optimal propeller was shown to move much faster than the previously developed random clusters.","We are interested in the regime, whereas the propeller turns in sync with the actuating field (provided w is not too high), rotating about the Z axis with angular velocity W = wẑ. This condition turns the second equation in Eq. Knowing the dynamic orientation of the object and thus the magnetic torque, L m , the translational velocity U can be readily found from the first equation in Eq.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=33937531914&p=1pl&v=1&x=Bje1-vLLATxlWcy3f0I9oA
10.1038/s41467-017-02597-8,Computer_Science_easy_603,"Regardless of the game or pairing, cheap talk doubled the amount of cooperation.",S# differs from S++ in two ways.,"""As it is, about half of the humans lied at some point. Regardless of the game or pairing, cheap talk doubled the amount of cooperation. And when machines used cheap talk, their human counterparts were often unable to tell whether they were playing a human or machine.","These results demonstrate the ability of S++ to effectively establish and maintain profitable long-term relationships with machines in arbitrary repeated games. S# differs from S++ in two ways. Second, S# also extends S++ by generating speech acts that convey the ""stream of consciousness"" of the algorithm (Figure 1d ).",[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/lets-make-a-deal-could-ai-compromise-better-than-humans/
10.1007/s10851-007-0055-0,Computer_Science_easy_605,He acknowledges that it's unlikely Van Gogh was making predictions about the turbulent eddies found in real stars when he painted The Starry Night.,It can be observed that in fact PDF curves depart from what is expected but we can not claim that this is the explanation (or the only one) but may give a clue to understand from where this turbulent effect comes from.,"If the turbulent swirls in The Starry Night didn't resemble the swirls in nature, then the viewer would likely notice something was off. He acknowledges that it's unlikely Van Gogh was making predictions about the turbulent eddies found in real stars when he painted The Starry Night. ""That has just been an amazing coincidence,"" he says.","If it is so, a blurring process on the digital image may lead to a gradual reduction of the turbulence. It can be observed that in fact PDF curves depart from what is expected but we can not claim that this is the explanation (or the only one) but may give a clue to understand from where this turbulent effect comes from. Further study of this topic is currently underway.",[1],Computer_Science,train,1.0,news,http://link.aps.org/doi/10.1103/Physics.12.45
10.1038/s41598-017-14834-7,Computer_Science_easy_606,"This is the next stage of work in our lab.""",Conditions without the same superscript letter (a-c) are significantly different at the 0.05 level with Tukey's multiple comparisons adjustment.,"""So we think load-adaptive devices could make an important difference for amputees. This is the next stage of work in our lab."" Brandt adds that the small study size may not reflect the entire amputee population, but instead highlights the need to consider more real-world tasks in prosthetics research.",Statistically significant changes are in bold font. Conditions without the same superscript letter (a-c) are significantly different at the 0.05 level with Tukey's multiple comparisons adjustment. p = 0.013).,[1],Computer_Science,train,1.0,news,http://healthmedicinet.com/news/study-shows-need-for-adaptive-powered-knee-prosthesis-to-assist-amputees/
10.1126/scirobotics.aan4582,Computer_Science_easy_607,"Not only does the program allow scientists to save time during the day, it allows Curiosity to continue working while they sleep.",The system is capable of finding targets in images from either MSL's NavCams or the ChemCam RMI.,"aAEGIS has increased the total data coming from ChemCam by operating during times when the rover would otherwise just be waiting for a command.a

Before the new software was deployed, it would take ground-based engineers up to 20 minutes to send or receive signals to or from Mars, and thatas assuming that the Earthas constant rotation did not prevent communication with the Red Planet at a given time. Not only does the program allow scientists to save time during the day, it allows Curiosity to continue working while they sleep. aAnd thereas no ability for people on the Earth to make decisions about what to target.","AEGIS has been adapted for the MSL mission to allow autonomous target selection and data acquisition for ChemCam. The system is capable of finding targets in images from either MSL's NavCams or the ChemCam RMI. In the NavCam case, the operation is analogous to the use on the MER mission, for finding targets in unknown terrain after a drive into a new locale.",[1],Computer_Science,train,1.0,news,http://www.redorbit.com/news/science/1113418326/curiosity-is-firing-lasers-on-mars-without-help-from-humans/
10.1016/j.ijmedinf.2014.06.005,Computer_Science_easy_608,"Young people may roll their eyes at older people who can't use technology as fast as they do, but it's wrong to say that older Americans can't use technology.",We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.,"Young people may roll their eyes at older people who can't use technology as fast as they do, but it's wrong to say that older Americans can't use technology. Our research posits that aging, technology and health issues will be inextricably linked in the future. Older adults more dependent upon technology

The march toward an ever-aging society underscores a major demographic and technological shift - the well-being of many of aging boomers will increasingly depend upon technology.",Tools that activate this social network around our frail elders will help independent living and hopefully decrease caregiver burden on their children. What this study added to our knowledge We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.,[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=39837460419&p=1pl&v=1&x=N9xQfcA5pXr9v0pk7vWoqA
10.1038/s41540-018-0054-3,Computer_Science_easy_609,"The new approach is much faster than the current way to predict the behavior of pathways, and promises to speed up the development of biomolecules for many applications in addition to commercially viable biofuels, such as drugs that fight antibiotic-resistant infections and crops that withstand drought.",5 and 6).,"The new approach is much faster than the current way to predict the behavior of pathways, and promises to speed up the development of biomolecules for many applications in addition to commercially viable biofuels, such as drugs that fight antibiotic-resistant infections and crops that withstand drought. Our approach could significantly shorten this step and become a new way to guide bioengineering efforts,"" Garcia Martin added. This allows scientists to quickly predict the function of a pathway even if its mechanisms are poorly understood -- as long as there are enough data to work with.","In spite of these hurdles, the method produced respectable qualitative and quantitative predictions of metabolite concentrations for a strain it has never seen before (Figs. 5 and 6). For some metabolites (33%), the predictions were quantitatively close to the measured profile: Acetyl-CoA (83.4 % error, Fig.",[1],Computer_Science,train,1.0,news,http://ct.moreover.com/?a=34174521596&p=1pl&v=1&x=JGvaSsaqLspDQuMsLwOEaA
10.3945/jn.113.188441,Medicine_0,"In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap.","Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men.","He said that can likely be attributed to biological differences (such as sex hormones and metabolism) between the sexes, as well as obesity and metabolic syndrome components. In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap. Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies.","The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ). Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men. Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women.","[3.0, 1.0, 1.0, 1.0]",Medicine,train,1.5,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1001/jamaneurol.2017.4618,Medicine_1,The researchers concluded that the presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae.,"Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001).","In addition, the positive and negative predictive values were 73.1 percent and 91.2 percent, respectively. The researchers concluded that the presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae. Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae.","Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001). The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2% (95% CI, 66.8%-83.7%) and 90.2% (95% CI, 86.8%-93.7%), respectively. In addition, the positive and negative predictive values were 73.1% (95% CI, 64.6%-81.6%) and 91.2% (95% CI, 87.9%-94.5%), respectively.","[4.0, 5.0, 4.0, 5.0, 5.0]",Medicine,train,4.6,news,http://www.diagnosticimaging.com/article/imaging-may-identify-potential-delayed-neurological-sequelae-after-carbon-monoxide-poisoning
10.1001/jama.2018.20578,Medicine_10,Now the picture is a little more clear.,"In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.","Even before this study arrived, the experts said people should only take regular low doses of aspirin on a doctor's advice - there are a lot of health factors to consider with the blood-thinning drug, even though we know it can be a very effective medicine. Now the picture is a little more clear. Over the thousands of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events.","19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=38333931091&p=1pl&v=1&x=RFNXfRDC7W6ykWiKhqzpYQ
10.1016/j.stemcr.2018.03.019,Medicine_102,X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.,The loss of one of the two X chromosomes in propagating female iPSCs is associated with genome-wide methylation gain.,"Note: material may have been edited for length and content. For further information, please contact the cited source. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.","Late in reprogramming, global hypomethylation is induced in a female-specific manner. The loss of one of the two X chromosomes in propagating female iPSCs is associated with genome-wide methylation gain. Collectively, our findings highlight the dynamic regulation of DNA methylation at enhancers during reprogramming and reveal that X chromosome dosage dictates global DNA methylation levels in iPSCs.","[2.0, 2.0, 2.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1016/j.cell.2018.04.034,Medicine_103,This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment.,"Like CDK12 mutant cases, SPOP-and MMRDdriven tumors were mostly diploid, while a large subset of ATM-and HRD-driven tumors showed large-scale aneuploidy ( Figure S3A ).","This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade. This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment. It could also explain why some prostate cancer patients have had exceptional responses to immunotherapy while the treatment has had lackluster results overall in prostate cancer.","None of the CDK12-mutated tumors exhibited a neuroendocrine phenotype. Like CDK12 mutant cases, SPOP-and MMRDdriven tumors were mostly diploid, while a large subset of ATM-and HRD-driven tumors showed large-scale aneuploidy ( Figure S3A ). The high number of focal gains was consistently observed in CDK12 mutant cases compared to those in the cohort with wild-type CDK12 ( Figure 1D ).","[3.0, 2.0, 2.0, 2.0]",Medicine,train,2.25,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.14814/phy2.13617,Medicine_104,"On evenings when using light-emitting tablets, participants' self-selected bedtimes were on average half an hour later, and they showed suppressed melatonin levels, delayed timing of melatonin secretion onset, and later sleep onset.","A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children.","On evenings when using light-emitting tablets, participants' self-selected bedtimes were on average half an hour later, and they showed suppressed melatonin levels, delayed timing of melatonin secretion onset, and later sleep onset. When using the tablets, participants rated themselves as less sleepy in the evenings and less alert in the first hour after awakening on the following mornings. ""These findings provide more evidence that light-emitting electronic devices have biological effects,"" said co-author Dr. Jeanne Duffy, of Brigham and Women's Hospital and Harvard Medical School.","To our knowledge, this study is the first to quantify the melatonin suppression response to evening light exposure in healthy 3-to 5-year-old children. A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children. Findings from this study mark an important step in addressing a gap in understanding the melatonin suppression response across the lifespan.","[4.0, 4.0, 3.0]",Medicine,train,3.6666666666666665,news,http://ct.moreover.com/?a=34124049276&p=1pl&v=1&x=KTWUvvClkwVOoq-BQDOMVw
10.1007/s00125-014-3400-z,Medicine_105,"Hazard ratios of type 1 diabetes increased with age at diagnosis of EV infection, with a more than doubling of the risk of type 1 diabetes (2.18 times increased risk) for children aged over 10 years at entry.",Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection.,"Overall incidence of type 1 diabetes was higher in the EV-infected children than in the non-EV infected group (5.73 vs. 3.89 per 100,000 people per year, showing a 48% increased incidence rate in EV-infected versus non-EV-infected children). Hazard ratios of type 1 diabetes increased with age at diagnosis of EV infection, with a more than doubling of the risk of type 1 diabetes (2.18 times increased risk) for children aged over 10 years at entry. No relationship of allergic rhinitis or bronchial asthma to type 1 diabetes was found.","The HRs of type 1 diabetes in children with allergic rhinitis, bronchial asthma or either one of these atopic diseases showed more variation than in those children without these diseases. Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection. The results suggest that a preventive strategy, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.","[3.0, 3.0, 4.0]",Medicine,train,3.333333333333333,news,http://www.sciencedaily.com/releases/2014/10/141017183715.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1186/1471-2431-13-162,Medicine_106,"Professor Exley said: ""Clearly the manufacturers of infant formulas are not concerned about reducing their content of aluminium and the extensive use of aluminium-based packaging for infant formulas seems to confirm this.",We consider that the aluminium content of all infant formulas investigated herein is too high and especially so considering that these products constitute either all or a substantial proportion of an infant's diet in the first months of their lives.,"The results show high levels of aluminium in each of the 30 infant formulas. Professor Exley said: ""Clearly the manufacturers of infant formulas are not concerned about reducing their content of aluminium and the extensive use of aluminium-based packaging for infant formulas seems to confirm this. ""There are no adequate criteria upon which to base a safety level for aluminium in infant formulas and for this reason it would be sensible to take action to reduce the level of aluminium to a lowest practicable level.",The concentration of aluminium in each of the 30 infant formulas is at least twice that which is recommended in the European Union for drinking water (50 μg/L) and in 14 of the milks it exceeds the maximum admissible level for drinking water of 200 μg/L . We consider that the aluminium content of all infant formulas investigated herein is too high and especially so considering that these products constitute either all or a substantial proportion of an infant's diet in the first months of their lives. Based upon the criteria for drinking water they are not fit for human consumption and they contravene article 5 of the Food Safety Act which states that 'infant formulas should not contain anything which might endanger the health of infants and young children' .,"[4.0, 2.0, 5.0, 5.0, 2.0]",Medicine,train,4.0,news,http://www.healthcanal.com/child-health/43790-action-needed-now-to-lower-the-content-of-aluminium-in-infant-formulas.html
10.1111/1365-2656.12871,Medicine_107,"Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","Crucially, we found relatively higher survival rates of individuals susceptible to both viruses compared to those susceptible to RHDV and immune to MYXV throughout the year (Figure 2 ), indicating that rabbits immune to MYXV have a lower survival rate than susceptible individuals.","""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute. ""The findings suggest a continuous benefit from both viruses and maximum impact on rabbit numbers if they act together.""","Individuals susceptible to both RHDV and MYXV had significantly higher survival rates than immune rabbits in all seasons (all odd ratio 1.13-1.67 with CIs between 1.02 and 1.99; Figure 2 and Supporting Information Figure   S3 ). Crucially, we found relatively higher survival rates of individuals susceptible to both viruses compared to those susceptible to RHDV and immune to MYXV throughout the year (Figure 2 ), indicating that rabbits immune to MYXV have a lower survival rate than susceptible individuals. Young rabbits, including those with maternal antibodies to either virus, had significantly lower survival rates than immune rabbits in spring (Figure 2 and Supporting Information Figure S4 ), indicating that waning protection by antibodies result in infection and potentially, mortality, later in the same year.","[4.0, 3.0, 3.0, 4.0, 5.0]",Medicine,train,3.8,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1001/jamapsychiatry.2018.1941,Medicine_109,"""This important cross-validation with participants from the USA provides support for the theory that the lateral orbitofrontal cortex is a key brain area that might be targeted in the search for treatments for depression.""","Interestingly, when the patients who had at some time been diagnosed with depression were removed, the links involving the lateral orbitofrontal cortex no longer exhibited the threshold level of significance.","""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls. ""This important cross-validation with participants from the USA provides support for the theory that the lateral orbitofrontal cortex is a key brain area that might be targeted in the search for treatments for depression."" Feng comments that these findings could have important public health implications, as both sleep problems and depression affect a large number of people.","The present findings were not on patients selected because of their existing depression but instead were on a general population in the United States in which a tendency to have depressive symptoms could be assessed. Interestingly, when the patients who had at some time been diagnosed with depression were removed, the links involving the lateral orbitofrontal cortex no longer exhibited the threshold level of significance. Moreover, if only the 92 participants who had had a diagnosis of depression were considered, then relatively high correlations with functional connectivities involving the lateral orbitofrontal cortex were found.","[3.0, 3.0, 4.0, 3.0, 4.0]",Medicine,train,3.4,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1001/jama.2014.15690,Medicine_11,"Researchers also wrote that other benefits of aspirin including prevention of cancer, should be considered.",We plan to conduct further analyses to establish whether aspirin had beneficial effects in particular subgroups of patients or if there were beneficial effects with respect to cancer prevention.,"""Japanese tend to have fewer heart attacks and more strokes, particularly more hemorrhagic strokes. In this study they had many more strokes than heart attacks, which is not something you'd see in a U.S. population,"" Gaziano said according to CBS News. Researchers also wrote that other benefits of aspirin including prevention of cancer, should be considered.","Therefore, it appears that aspirin is unlikely to show a clinically important benefit in the overall population included in this study. We plan to conduct further analyses to establish whether aspirin had beneficial effects in particular subgroups of patients or if there were beneficial effects with respect to cancer prevention. Study limitations need to be considered.","[4.0, 5.0, 4.0, 4.0, 2.0]",Medicine,train,3.8,news,http://www.counselheal.com/articles/13333/20141120/aspirin-cut-heart-problems-risk.htm
10.1126/sciadv.aat5107,Medicine_110,"The researchers tested their BioBits kits in the Chicago Public School system, and demonstrated that students and teachers were able to perform the experiments in the kits with the same success as trained synthetic biology researchers.",We anticipate that the availability of our BioBits™ kits and the data reported here will encourage teaching and broaden participation in the field of synthetic biology.,"When fruit DNA is added to the sensor-containing FD-CF pellets, only the sensors that are designed to open in the presence of each fruit's RNA will produce the fluorescent protein. The researchers tested their BioBits kits in the Chicago Public School system, and demonstrated that students and teachers were able to perform the experiments in the kits with the same success as trained synthetic biology researchers. ""We show that it is possible to use freeze-dried, cell-free extracts along with freeze-dried synthetic biology components to conduct innovative educational experiments in classrooms and other low-resource settings.","Titrating the amount of DNA template results in varying levels of fluorescent protein production, which are visible to the naked eye and under a blue or black light. We anticipate that the availability of our BioBits™ kits and the data reported here will encourage teaching and broaden participation in the field of synthetic biology. We observed that all proteins expressed with high soluble yields (between 160 and >1100 g ml −1 ) ( Fig.","[4.0, 5.0, 4.0]",Medicine,train,4.333333333333333,news,http://ct.moreover.com/?a=34696777548&p=1pl&v=1&x=pxhPjHWCPi8TfA-LxM_Vbw
10.1038/s41598-018-25573-8,Medicine_111,"""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor.","In addition, administration of 100 μg of doxorubicin caused significant damage to various organs in the embryo (Fig.","In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered,"" write the investigators. ""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles.","In the case of free doxorubicin, none of the eggs survived injection of 200 μg of doxorubicin. In addition, administration of 100 μg of doxorubicin caused significant damage to various organs in the embryo (Fig. 5 left picture) .","[1.0, 3.0, 4.0, 2.0, 2.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1038/s41467-018-07557-4,Medicine_112,"""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper.","Results show that by 2050 3.6 million people, which constitutes about three quarters of the current population in the Northern Hemisphere permafrost area, may be affected by damage to infrastructure associated with permafrost thaw (Fig.","The team found that 3.6 million people--three quarters of the current population in the Northern Hemisphere permafrost area--may be affected by infrastructure damage from permafrost thaw. ""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper. The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports.","The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved. Results show that by 2050 3.6 million people, which constitutes about three quarters of the current population in the Northern Hemisphere permafrost area, may be affected by damage to infrastructure associated with permafrost thaw (Fig. 2a , Supplementary  Tables 2 and 3 , Supplementary Data 1) (results for 2061-2080 are presented in Supplementary Fig.","[4.0, 5.0, 4.0]",Medicine,train,4.333333333333333,news,http://ct.moreover.com/?a=37952323296&p=1pl&v=1&x=YZkcSHKHdqhjfYYiUvZ_gw
10.1016/j.cell.2018.04.034,Medicine_114,"That jumped to 7 percent for metastatic cancer, which indicates a more-aggressive form of the disease.",The majority of CDK12 mutations (83%) were truncating and resulted in the loss of the kinase domain.,"Researchers found loss of CDK12 in only about 1 percent of early prostate cancer samples. That jumped to 7 percent for metastatic cancer, which indicates a more-aggressive form of the disease. ""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease.","CRPC genomes are more highly mutated than those of localized tumors; however, the magnitude of the increased mutation rate is not sufficient to explain the increased frequency of biallelic loss of CDK12. The majority of CDK12 mutations (83%) were truncating and resulted in the loss of the kinase domain. Missense mutations were clustered around conserved residues in the kinase domain ( Figure S1 ).","[1.0, 3.0, 2.0, 1.0, 2.0]",Medicine,train,1.8,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1001/jama.2018.7028,Medicine_115,"This might be a marker for the severity of the stress disorder, the researchers say, with the people who are worse affected more likely to be prescribed antidepressants.","Restricting to participants with more than 5 years of followup, patients with stress-related disorders had a higher cumulative incidence of autoimmune diseases compared with their matched unexposed individuals across the follow-up period (eFigure3intheSupplement).","Those with stress disorders were 30-40 percent more likely to go on to develop one of 41 autoimmune diseases as well, on average - 9.1 people per thousand for the stress disorder group, 6.5 people per thousand for their siblings, and 6 people per thousand for a matched group without PTSD or other stress disorders. This might be a marker for the severity of the stress disorder, the researchers say, with the people who are worse affected more likely to be prescribed antidepressants. It's also worth noting that the longer SSRI use continued for, the more the risk fell.","A score of zero shows no comorbidities; the higher the score, the more likely the predicted outcome will result in mortality or higher medical resource use. Restricting to participants with more than 5 years of followup, patients with stress-related disorders had a higher cumulative incidence of autoimmune diseases compared with their matched unexposed individuals across the follow-up period (eFigure3intheSupplement). Additional adjustment for medical surveillance level yielded somewhat lower point estimates (eTable 6 in the Supplement) while changing the definitions for history of other psychiatric disorders and autoimmune disease, and the extension of the lag-time period yielded similar results (eTables 7 and 8 in the Supplement).","[2.0, 3.0, 4.0, 2.0, 1.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=34364069500&p=1pl&v=1&x=8wgdAvdMNER9LVXLJEBn3Q
10.1007/s13524-014-0321-x,Medicine_116,"Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents.","Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility.","Those who have children at an older age or who are more educated have a particularly positive response to a first birth. Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.","Decreasing gains in subjective well-being at higher birth orders may inhibit people from moving to parity three. Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility. In addition to the type of social learning about the optimal timing and number of children to have , fertility decisions may be affected by observing the subjective experiences of others.","[3.0, 1.0, 1.0, 1.0, 2.0]",Medicine,train,1.6,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Medicine_117,"""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim.","We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has.","In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status. ""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased.","Importantly, we observe that happiness increases before birth, suggesting that the happiness gain around the time of birth may capture not only the effect of the birth but also the complex childbearing process that may involve partnership formation, partnership quality, and increased sexual activity. We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has. These results were similar in Britain and Germany.","[4.0, 3.0, 4.0]",Medicine,train,3.6666666666666665,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1001/jama.2018.20578,Medicine_118,That is not the case in the United States.,"19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice.","The results of that analysis turned out to be similar to those of the overall analysis, including the finding of an increased risk of major bleeding outcomes. That is not the case in the United States. No one should stop taking aspirin prescribed by their doctor on the basis of this one study.","Fourth, 8 trials began randomizing study participants over 20 years ago, with 3 trials initiating recruitment in the 1970s and 1980s. 19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=38341163535&p=1pl&v=1&x=jH6VKychTf5F9c4QLWbbDg
10.1073/pnas.1515528113,Medicine_12,"More bang for the buck

In addition, efforts to expand HPV vaccination, particularly in states with low coverage, could prevent even more cancers and deaths, researchers say, adding that due to interstate migration, all states would benefit if they aligned vaccination policy.","Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders.","""Adopting the new vaccine is always cost-effective relative to the old vaccines."" More bang for the buck

In addition, efforts to expand HPV vaccination, particularly in states with low coverage, could prevent even more cancers and deaths, researchers say, adding that due to interstate migration, all states would benefit if they aligned vaccination policy. ""The greatest benefits of HPV vaccination both in terms of cancer reduction and health care costs are realized when policy promoting vaccination is coordinated across states,"" says Alison Galvani, professor of epidemiology and director of CIDMA.","Because of the impact of herd immunity, any expansion in coverage will be much more effective in reducing cancer incidence and healthcare costs if targeted in those states with the lowest coverage. Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders. Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine.","[3.0, 5.0, 4.0, 4.0, 5.0]",Medicine,train,4.2,news,http://www.futurity.org/gardasil-9-hpv-vaccine-1142472/
10.1016/j.ejca.2017.11.022,Medicine_120,"Unfortunately, the study did not identify any women who avoided all meat, so it doesnat tell us if a vegetarian diet would have further reduced the risk of breast cancer.","Among participants who had the highest intake of processed meat, the incidence of breast cancer was 2.55 per 1,000 population per annum among those with low cooked vegetable intake and 2.35 per 1,000 per annum among those with high intake.","Since some cases of breast cancer have a genetic component, we should remember this group may have greater susceptibility to breast cancer than the general population. Unfortunately, the study did not identify any women who avoided all meat, so it doesnat tell us if a vegetarian diet would have further reduced the risk of breast cancer. Another major review confirmed the processed meat results and found only a very small increase in breast cancer related to fresh red meat.","This was due to the absolute risk already being higher in this sub-group; among participants who ate no processed meat, the incidence of breast cancer was 2.46 per 1,000 population per annum among those with low intake of cooked vegetables compared with only 2.01 per 1,000 per annum among those with high vegetable intake. Among participants who had the highest intake of processed meat, the incidence of breast cancer was 2.55 per 1,000 population per annum among those with low cooked vegetable intake and 2.35 per 1,000 per annum among those with high intake. There was no significant interaction with menopausal status.","[2.0, 2.0, 2.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=40018041593&p=1pl&v=1&x=0-S1_nh44txdcV7SbNzZRw
10.1073/pnas.1515528113,Medicine_123,"In terms of number of cancers averted per vaccine, there are decreasing marginal returns in states that already have high coverage.","Increases in coverage between 2013 and 2014 were observed in several jurisdictions that received resources from the CDC PPHF to provide educational outreach to physicians, parents, and adolescents and for other measures .","More resources ""do lead to improvements in coverage. In terms of number of cancers averted per vaccine, there are decreasing marginal returns in states that already have high coverage. You get more bang for your buck by focusing first on states with lower coverage.""","Strategies that did not include switching to 9vHPV would not be cost-effective at any WTP. Increases in coverage between 2013 and 2014 were observed in several jurisdictions that received resources from the CDC PPHF to provide educational outreach to physicians, parents, and adolescents and for other measures . This experience suggests that additional resources may be necessary to increase uptake further as coverage rises .","[2.0, 1.0, 1.0, 1.0]",Medicine,train,1.25,news,http://www.futurity.org/gardasil-9-hpv-vaccine-1142472/
10.1016/j.cell.2018.04.034,Medicine_124,The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant.,"These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results.","""Because prostate cancer is so common, 7 percent is a significant number. The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant. This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy,"" says senior study author Arul Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology.","In line with this possibility, high levels of CCL21 and CCL25 may mediate dendritic cell tumor trafficking and neoantigen-specific T cell clonal expansion (Chan et al., 1999; Gosling et al., 2000; . These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results. A plausible explanation is in the genetics of prostate cancer.","[2.0, 2.0, 1.0, 4.0]",Medicine,train,2.25,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1038/srep01456,Medicine_125,"The study also revealed that despite sometimes being separated by hundreds of miles, resistant bedbug colonies utilized many of the same genes to protect themselves against pyrethroid insecticides.",Our data showed that multiple mechanisms involved in pyrethroid resistance is not only a phenomenon occurring in laboratory bed bug strains but also is widespread in naturally occurring bed bug populations (Figs.,"Insecticide Armor

Further investigation revealed that all of these ""overexpressed"" genes were active in the tough outer shell of resistant bedbugs, and either helped neutralize pyrethroid insecticides before they could take effect or prevented them from entering the insects' bodies in the first place. The study also revealed that despite sometimes being separated by hundreds of miles, resistant bedbug colonies utilized many of the same genes to protect themselves against pyrethroid insecticides. Bedbugs by themselves aren't very mobile, but Haynes suspects the bugs are catching rides with humansaor rather, their furniture.","3D) is also interesting and further research is required to understand functional significance of this observation. Our data showed that multiple mechanisms involved in pyrethroid resistance is not only a phenomenon occurring in laboratory bed bug strains but also is widespread in naturally occurring bed bug populations (Figs. Inactivation of four P450 target genes significantly enhanced the susceptibility of resistant bed bugs to pyrethroid insecticide, which further confirmed the involvement of P450-mediated metabolic detoxification in pyrethroid resistance of bed bugs.","[4.0, 5.0, 3.0, 4.0, 5.0]",Medicine,train,4.2,news,http://news.nationalgeographic.com/news/2013/13/130314-bedbug-insecticide-resistance-pest-science/
10.1210/jc.2013-2350,Medicine_126,"""Our study indicates women who have PCOS have twice as many hospital admissions as women without the condition.","Some women with PCOS and a eumenorrheic menstrual history may still experience anovulation, and a midluteal serum progesterone may be helpful as an additional screening test.","""PCOS has profound implications for a women's reproductive health as well as her long-term risk of chronic illness,"" said one of the study's authors, Roger Hart, MD, MRCOG, FRANZCOG, CREI, of the University of Western Australia and Fertility Specialists of Western Australia, both in Perth, Australia. ""Our study indicates women who have PCOS have twice as many hospital admissions as women without the condition. Additional health care resources should be directed to address the risks facing this population.""","Nevertheless, lifetime fecundity in Swedish women with PCOS was similar to controls, and almost three-fourths of women with PCOS conceived spontaneously . Some women with PCOS and a eumenorrheic menstrual history may still experience anovulation, and a midluteal serum progesterone may be helpful as an additional screening test. Male factor infertility or tubal occlusion must also be considered (one study in PCOS found a nearly 10% rate of severe oligospermia and a 5% rate of bilateral tubal occlusion) (76).","[2.0, 1.0, 2.0]",Medicine,train,1.6666666666666667,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1007/s00127-012-0548-z,Medicine_127,"Unlike PMS, which most women of reproductive age will experience to a greater or lesser degree, the symptoms of PMDD are so intense they disrupt everything in the sufferer's life, from relationships to work.","These findings suggest that clinicians treating women with PMDD should assess and be vigilant for signs of suicidal behavior, and that clinicians might evaluate and treat the premenstrual symptoms of women who express suicidal ideation, plans, or attempts.","Until next month, when it all begins again. Unlike PMS, which most women of reproductive age will experience to a greater or lesser degree, the symptoms of PMDD are so intense they disrupt everything in the sufferer's life, from relationships to work. Of the 12 women with PMDD I spoke to, all had at some point adjusted their work life and dreams to suit the disorder.","In conclusion, this study is the first to demonstrate a strong, independent association between PMDD and suicidal ideation, plans, and attempts among a nationally representative sample of women. These findings suggest that clinicians treating women with PMDD should assess and be vigilant for signs of suicidal behavior, and that clinicians might evaluate and treat the premenstrual symptoms of women who express suicidal ideation, plans, or attempts. By targeting a gender-specific risk factor for non-fatal suicidal behavior, clinicians may be able to address a substantial public health problem among reproductive-aged women.","[2.0, 4.0, 4.0, 2.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=38040647815&p=1pl&v=1&x=vWjKUbywlMMZxsOdDZ84HQ
10.1080/08870446.2013.818674,Medicine_128,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.","Thus, self-regulation alone might not suffice but smokers might be in need of both high self-regulation skills and high levels of received social support from their spouses.","Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations. Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette).","Alternatively, the synergistic effects of social support and individual regulation variables as for example found by for the association of attitudes and intentions may also appear in the context of smoking cessation. Thus, self-regulation alone might not suffice but smokers might be in need of both high self-regulation skills and high levels of received social support from their spouses. Of these, 72.6% (n = 77) were men and the mean age was 40.67years (SD= 10.03, ranging from 19 to 72).","[4.0, 4.0, 5.0, 5.0, 4.0]",Medicine,train,4.4,news,http://www.healthcanal.com/substance-abuse/41119-rauchstopp-zu-zweit.html
10.1111/cdev.12250,Medicine_129,"The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote.","These analyses indicate numerous simple correlations between early adolescent pseudomature behaviors (i.e., minor deviance, selection of attractive peers, precocious romantic behavior), and initial (but not later) levels of popularity, and between these early pseudomature behaviors and later negative outcomes, all of which are explored further below.","In fact, just the opposite happened. The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","For descriptive purposes, Table 1 also presents simple correlations among all primary constructs examined in the study. These analyses indicate numerous simple correlations between early adolescent pseudomature behaviors (i.e., minor deviance, selection of attractive peers, precocious romantic behavior), and initial (but not later) levels of popularity, and between these early pseudomature behaviors and later negative outcomes, all of which are explored further below. Valuing of popularity was a significant predictor of each of these behaviors after accounting for gender and income (b = .15, p = .01; b = .20, p = .004; b = .16, p = .04, for minor delinquency, attractiveness of close peer, and precocious romantic activity, respectively).","[4.0, 2.0, 2.0, 4.0, 4.0]",Medicine,train,3.2,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1098/rsos.171474,Medicine_13,"The title lays it out plainly: ""Violent video game engagement is not associated with adolescents' aggressive behaviour.""","Despite the null findings identified in the present study, history gives us reason to suspect the idea that violent video games drives aggressive behaviour will remain an unsettled question for parents, pundits and policy-makers.","The title lays it out plainly: ""Violent video game engagement is not associated with adolescents' aggressive behaviour."" Their top-line finding is that their study ""did not support the position that violent gaming relates to aggressive behaviour."" This contradicts the consensus hammered out by an American Psychological Association task force on violent video games in 2017.","Until such findings are confirmed, however, we strongly would caution about drawing impulsive, thoughtless or potentially stigmatizing conclusions about members of such groups . Despite the null findings identified in the present study, history gives us reason to suspect the idea that violent video games drives aggressive behaviour will remain an unsettled question for parents, pundits and policy-makers. Although our results do have implications for these stakeholders, the present work holds special significance for those studying technology effects, in general, and video games, in particular.","[3.0, 1.0, 5.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1016/j.jpeds.2017.10.028,Medicine_130,"The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researchers said.","There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researchers said. ""While we can't say that spanking causes later violence, it follows that if a kid learns that physical punishment is a way to solve conflict, he/she may carry that over into conflicts with later intimate partners,"" said study senior author Jeff Temple. About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[1.0, 2.0, 2.0, 1.0, 2.0]",Medicine,train,1.6,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1001/jamapsychiatry.2015.0500,Medicine_131,"It's also not necessarily strange that these drugs were used in cases where the child had no mental health diagnosis, though it could suggest overuse.","However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010).","But because of the unknown risks that come with flooding a maturing brain with these drugs, they should be utilized only when it's absolutely necessary. It's also not necessarily strange that these drugs were used in cases where the child had no mental health diagnosis, though it could suggest overuse. The authors hope that their findings will prompt others to develop better, safer approaches to treating these serious but manageable conditions.","Most young people treated with antipsychotics in each age group filled 1 or more antipsychotic prescriptions that were written by a psychiatrist (57.9% of young children, 71.9% of older children, 77.9% of adolescents, and 70.4% of young adults in 2010) ( Table 2) . However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010). Younger children treated with antipsychotics were proportionately the least likely of the 4 age groups to have filled 1 or more antipsychotic prescriptions from a psychiatrist.","[2.0, 3.0, 5.0, 3.0]",Medicine,train,3.25,news,http://www.medicaldaily.com/antipsychotics-are-being-given-kids-temporary-behavioral-problems-adhd-341188
10.1177/0956797617692041,Medicine_132,But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves.,"Thus, the increased consumption observed in the refill condition was driven by consumption of large drinksthe only drink size that included free refills.","This may have happened, the researchers surmise, because consumers wanted to get their ""money's worth"" - that is, they consumed more of the refill since they had already paid for it. But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves. ""Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption,"" the researchers write.","For the large drink, however, the participants consumed 44.0% more calories in the refill condition than in the typical-portion condition (refill: M = 208.05 kcal, SD = 106.69; typical portion: M = 144.51 kcal, SD = 50.43), t(111) = 4.10, p < .001, d = 0.77. Thus, the increased consumption observed in the refill condition was driven by consumption of large drinksthe only drink size that included free refills. The consumption difference held: The participants in the refill condition consumed 26.1% more calories than those in the typicalportion condition (refill: M = 90.46 kcal, SD = 97.39; typical portion: M = 71.71 kcal, SD = 68.05), t(468) = 2.43, p = .016.","[5.0, 2.0, 4.0, 1.0, 2.0]",Medicine,train,2.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1016/j.socscimed.2018.10.008,Medicine_133,"Furthermore, women whose births had complications were 174 percent more likely to experience PND compared to those women who had no complications.",We found the odds of PND increased by 71-79% when male infants were born compared to female infants.,"Specifically, University of Kent investigators discovered that women who give birth to males are 71-79 percent more likely to develop PND. Furthermore, women whose births had complications were 174 percent more likely to experience PND compared to those women who had no complications. As a result of their findings, investigators Sarah Johns M.D., and Sarah Myers M.D., believe health care professionals may be able to provide better care for depression by understanding these new risk factors.","We found the odds of PND increased by 71-79% when male infants were born compared to female infants. The occurrence of birth complications increased the odds of PND by 174% compared to having no complications. Testing for interaction effects found that, while always at increased risk of PND, women with a tendency towards symptoms of depression, anxiety, and stress at other points in the life course had reduced odds of PND when experiencing birth complications, suggesting such women may elicit greater support.","[2.0, 2.0, 2.0, 3.0, 2.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=37619913738&p=1pl&v=1&x=c7HTLKfs7Zb4iDFM2zXdrQ
10.1016/j.socscimed.2018.10.008,Medicine_134,"Furthermore, women whose births had complications were 174 percent more likely to experience PND compared to those women who had no complications.","We did not find much evidence for the additive effects of birth complications with other PND risk factors in our sample (low SES, low social support, and a history of depression, anxiety, and stress) as anticipated.","Specifically, University of Kent investigators discovered that women who give birth to males are 71-79 percent more likely to develop PND. Furthermore, women whose births had complications were 174 percent more likely to experience PND compared to those women who had no complications. As a result of their findings, investigators Sarah Johns M.D., and Sarah Myers M.D., believe health care professionals may be able to provide better care for depression by understanding these new risk factors.","Irrespective of whether post-birth infections are experienced, birth complications are likely to be stressful for women, particularly if they resulted in emergency procedures being undertaken. We did not find much evidence for the additive effects of birth complications with other PND risk factors in our sample (low SES, low social support, and a history of depression, anxiety, and stress) as anticipated. Only one predicted interaction effect was found; male infants increased PND risk when associated with complicated births when PND was measured by clinical diagnosis, but not when PND was determined retrospectively, and inclusion of the interaction term only marginally improved the model performance.","[3.0, 2.0, 3.0, 3.0, 3.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=37619913738&p=1pl&v=1&x=c7HTLKfs7Zb4iDFM2zXdrQ
10.1186/s12916-017-0986-2,Medicine_135,"""This study highlights how common postoperative complications are among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults who may be at risk,"" she said.","One study found that, while frail patients with postoperative complications had prolonged hospitalizations (P < 0.001), those without postoperative complications did not (P = 0.19) .","""Older adults are a diverse group of patients whose risk of postoperative complications is not solely defined by their age, co-morbidities (multiple health problems) or the type of surgical procedure they receive,"" Watt said. ""This study highlights how common postoperative complications are among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults who may be at risk,"" she said. Identifying and addressing risk factors before surgery -- especially smoking and depressive symptoms, Watt said -- could be helpful.","Among six studies that investigated frailty as a prognostic factor for prolonged hospitalization, there was a significant association identified in four studies . One study found that, while frail patients with postoperative complications had prolonged hospitalizations (P < 0.001), those without postoperative complications did not (P = 0.19) . Age was identified as a significant prognostic factor for prolonged hospitalization in only two of six studies 2 .","[3.0, 3.0, 2.0, 2.0, 1.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=33000673455&p=1pl&v=1&x=ZUA80X35mG1U_VnPyqM0hw
10.1016/j.jalz.2018.06.2856,Medicine_136,"""This paper is pointing to a new area of opportunity,"" he said.","Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat.","The researchers said several factors suggest the effects they uncovered were specific to ophthalmic conditions and not merely age-related phenomenon. ""This paper is pointing to a new area of opportunity,"" he said. Note: material may have been edited for length and content.","In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not. Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat. Supplementary data related to this article can be found at https://doi.org/10.1016/j.jalz.2018.06.2856.","[3.0, 5.0, 1.0, 3.0, 3.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1038/nature13850,Medicine_137,"According to the study, ""the unexpected morphology suggests that the magnetic field's role during the accretion of a T Tauri star is more complex than the current theoretical understanding,"" and that magnetic fields are important in forming a planetary system like our own.",Misalignment of the field lines with the rotation axis can help overcome magnetic braking to create a centrifugally supported disk at the 0 AU scale .,"These CARMA observations found the first detection of the magnetic field morphology in a T Tauri star disk. According to the study, ""the unexpected morphology suggests that the magnetic field's role during the accretion of a T Tauri star is more complex than the current theoretical understanding,"" and that magnetic fields are important in forming a planetary system like our own. While the magnetic field morphology appears significantly more toroidal than poloidal, neither morphology is a good fit.","At the 1,000 AU scale, structured magnetic fields are observed around young, low-mass protostars , but the fields appear to be randomly aligned with respect to the inferred disk . Misalignment of the field lines with the rotation axis can help overcome magnetic braking to create a centrifugally supported disk at the 0 AU scale . Further disk evolution can be driven by magnetorotational instability 2 or a magnetocentrifugal wind 1,9 ; a toroidally dominant disk field is expected in the former scenario, and a significant poloidal field is required for the latter (at least near the wind launching surface).","[4.0, 1.0, 1.0, 3.0, 2.0]",Medicine,train,2.2,news,http://www.futurity.org/stars-magnetic-field-803342/
10.1001/jamapediatrics.2013.4951,Medicine_138,"A Genetic Risk for Big Appetites

The importance of catching these signs could become greater if the child is already genetically predisposed to a large appetite.","Similar patterns are to be expected in the wider population; therefore, this study corroborates the hypothesis that a hearty appetite in infancy is a risk factor for faster weight gain.","This behavior could put her at risk of gaining weight faster than is good for her."" A Genetic Risk for Big Appetites

The importance of catching these signs could become greater if the child is already genetically predisposed to a large appetite. ""As expected, we found that children with a higher PRS score were likely to have larger BMI and waist circumference,"" Dr. Clare Llewellyn, lead author of this study, said in the release.","25 Our findings indicate that within the same family the sibling with the higher appetite grows faster than the sibling with the lower appetite. Similar patterns are to be expected in the wider population; therefore, this study corroborates the hypothesis that a hearty appetite in infancy is a risk factor for faster weight gain. Our study has several strengths.","[4.0, 3.0, 4.0]",Medicine,train,3.6666666666666665,news,http://www.medicaldaily.com/controlling-appetite-may-be-best-bet-curbing-childhood-obesity-269480
10.1152/ajpregu.00204.2013,Medicine_139,"This study, the first to look at the effects of CO on the placenta in mice, found that exposing the animals to inhalable CO increased blood flow and vascular growth in the developing placenta, created more, bigger, and stronger connections to the mother's uterus, a process that provides more oxygen and nutrients to the fetus.","We demonstrated that the ratio of placental total VEGFR1 to VEGF was significantly reduced in both chronic and acutely exposed animals, indicating a possible mechanism for the placental vessel changes noted.","Although toxic at high levels, low levels of CO are produced naturally by the body and have positive effects. This study, the first to look at the effects of CO on the placenta in mice, found that exposing the animals to inhalable CO increased blood flow and vascular growth in the developing placenta, created more, bigger, and stronger connections to the mother's uterus, a process that provides more oxygen and nutrients to the fetus. And, since PE is a multifaceted disorder that begins with abnormal placental development before progressing to maternal disease, the results also suggest the possibility of preventing or treating early PE in humans with controlled CO dosages.","Perhaps the CO effect is more strongly related to a decreased sFLT1 release, thus increasing the VEGF bioavailability. We demonstrated that the ratio of placental total VEGFR1 to VEGF was significantly reduced in both chronic and acutely exposed animals, indicating a possible mechanism for the placental vessel changes noted. The placentas of women who smoke in pregnancy have been reported as larger in size, with an increase in branching of the vascular tree ; the authors suggest that this alteration is an adaptation response, increasing surface area for nutrient transfer.","[2.0, 2.0, 4.0, 2.0, 2.0]",Medicine,train,2.4,news,http://www.sciencedaily.com/releases/2013/09/130919154253.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jama.2013.285112,Medicine_14,"We have to attack the problem with renewed commitment, utilizing both the interventions documented to reduce smoking and perhaps new regulatory approaches.","In women, life expectancy at age 40 years increased 5.4 years (from 37.4 to 42.7 years), but without tobacco control, it would have been projected to increase by only 3.8 years (from 37.3 to 41.2 years).","It is seen by many as a pivotal moment in American public health and as the opening salvo in an ongoing effort to convince people to stop smoking. We have to attack the problem with renewed commitment, utilizing both the interventions documented to reduce smoking and perhaps new regulatory approaches. ""The job of tobacco control is far from done.""","Hence, 2.3 years (CR, 1.8-2.5) or 30% (CR, 23%-32%) of improved life expectancy for men is projected to be associated with tobacco control. In women, life expectancy at age 40 years increased 5.4 years (from 37.4 to 42.7 years), but without tobacco control, it would have been projected to increase by only 3.8 years (from 37.3 to 41.2 years). Tobacco control appears to be associated with 1.6 years (CR, 1.4-1.7) of the improvement in life expectancy for women or 29% (CR, 25%-32%) of the gain.","[1.0, 3.0, 2.0, 1.0]",Medicine,train,1.75,news,http://www.healthcanal.com/public-health-safety/46414-millions-of-lives-saved-since-surgeon-general-s-tobacco-warning-50-years-ago.html
10.1001/jamapsychiatry.2018.1941,Medicine_142,"In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).","In particular, in this subgroup of 92, correlations were found for the Depressive Problems score for 6 links involving the lateral orbitofrontal cortex (to the left middle frontal gyrus: r = 0.410; P < .001; left supramarginal gyrus: r =0 .","This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.","This was supported by the finding of correlations between the depressive score and many functional connectivities involving the lateral orbitofrontal cortex when only this subgroup of 92 were included. In particular, in this subgroup of 92, correlations were found for the Depressive Problems score for 6 links involving the lateral orbitofrontal cortex (to the left middle frontal gyrus: r = 0.410; P < .001; left supramarginal gyrus: r =0 . 3 77 ; P < .001; left middle cingulate and paracingulate gyri: r =0 .38 5;P < .001; left precuneus: r = 0.430; P < .001; left insula: r = 0.348; P < .001; and to 2 ROIs within the right middle cingulate and paracingulate gyri: r = 0.368 and r = 0.402; P < .001 for both), 7 links involving the anterior cingulate cortex (to the left supplementary motor area: r = 0.446; P < .001; right postcentral gyrus: r = 0.368; P < .001; temporal pole [middle temporal gyrus]: r = 0.338; Depression score","[2.0, 4.0, 3.0, 4.0, 3.0]",Medicine,train,3.2,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1038/s41598-018-30980-y,Medicine_143,"""This study demonstrates that napping is beneficial to memory processing,"" they point out.",This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children.,"As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","A significant benefit of napping was observed only when changes across the entire 24-hour period were considered. This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children. A day of continuous wake led to significant forgetting, particularly for the habitually napping children, which could not be reversed with overnight sleep.","[5.0, 5.0, 5.0, 2.0, 4.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1073/pnas.1504869112,Medicine_144,"The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests.","Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining. ""This is the first time the effect of lianas on carbon cycling has been shown in such detail and on a large scale,"" Powers says.","Longer-term data are needed to assess whether this initial difference in carbon sink potential persists over time. Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests. While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change.","[3.0, 2.0, 2.0]",Medicine,train,2.333333333333333,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1001/jamapsychiatry.2018.1941,Medicine_146,"An analysis of the records of 9,735 people living with depressive problems found that there was increased activity between these brain regions in people who also reported disrupted sleep patterns, and that's a crucial discovery in our understanding of these conditions.","Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig.","Researchers found a strong connection between the dorsolateral prefrontal cortex (responsible for short-term memory), the precuneus (linked with ideas of the self) and the lateral orbitofrontal cortex (associated with negative emotions). An analysis of the records of 9,735 people living with depressive problems found that there was increased activity between these brain regions in people who also reported disrupted sleep patterns, and that's a crucial discovery in our understanding of these conditions. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","In the reverse direction, only 2 links significantly mediated effects of sleep quality on depressive problems with FDR correction. Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig. S4 ) than for the effect in the opposite direction described above.","[3.0, 2.0, 1.0, 2.0, 3.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1038/s41467-018-05709-0,Medicine_147,"In their experiments, the pharmacologists were able to show that it not only suppresses acute itch, but is also effective against chronic itch.","Our results indicate that drugs targeting α2 and α3GABA A receptors are well-suited to alleviate itch, including nonhistaminergic chronic itch for which currently no approved treatment exists.","In their experiments, the pharmacologists were able to show that it not only suppresses acute itch, but is also effective against chronic itch. Mice that were administered with the drug scratched themselves less often, and their skin changes healed significantly quicker than in animals that were given a placebo. The same itch-suppressant effect was also observed in tests with dogs carried out by the researchers in cooperation with the University of Zurich's Veterinary Department.","Systemic treatment with an α2/α3GABA A receptor selective modulator alleviates also chronic itch in a mouse model of atopic dermatitis and in dogs sensitized to house dust mites, without inducing sedation, motor dysfunction, or loss of antipruritic activity after prolonged treatment. Our results indicate that drugs targeting α2 and α3GABA A receptors are well-suited to alleviate itch, including nonhistaminergic chronic itch for which currently no approved treatment exists. These itch-relay pathways appear to be under tight control by dorsal horn inhibitory neurons.","[3.0, 4.0, 5.0, 3.0, 5.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=34818663460&p=1pl&v=1&x=L-gib_N5MhiGEP62jfuz-g
10.1016/j.mayocp.2014.07.004,Medicine_148,The investigators found that smokers who used a combination of specialist behavioral support and medication in their quit attempts reported higher levels of urges to smoke than did smokers who tried to quit unaided.,"After adjusting for this confounder, we found that smokers who use a combination of specialist behavioral support and medication in their quit attempts had almost 3 times the odds of success than did those who used neither medication nor behavioral support.","A total of 23% reported not smoking at the end of the six-month period. The investigators found that smokers who used a combination of specialist behavioral support and medication in their quit attempts reported higher levels of urges to smoke than did smokers who tried to quit unaided. After adjusting for this, they found smokers using the combination approach had almost three times the odds of success than did those who used neither medication nor behavioral support.","8 Still, smokers who used medication and behavioral support reported higher levels of urges to smoke than did smokers who tried to quit unaided. After adjusting for this confounder, we found that smokers who use a combination of specialist behavioral support and medication in their quit attempts had almost 3 times the odds of success than did those who used neither medication nor behavioral support. We also found that smokers who bought nicotine replacement therapy (NRT) over the counter with no behavioral support had similar odds of success at stopping as did those who stop without any aid.","[1.0, 3.0, 3.0, 5.0]",Medicine,train,3.0,news,http://www.sciencedaily.com/releases/2014/10/141008083514.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamapsychiatry.2015.0500,Medicine_149,"This study, which may be the broadest look yet at use of antipsychotics in children, found that most children had not been diagnosed with a mental disorder before being given antipsychotics.","However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010).","Boys were more likely to be given the medications. This study, which may be the broadest look yet at use of antipsychotics in children, found that most children had not been diagnosed with a mental disorder before being given antipsychotics. ADHD was the most common diagnosis, applied to 52.5 percent of young children, 60 percent of older children, and 34.9 percent of teenagers diagnosed with ADHD.","Most young people treated with antipsychotics in each age group filled 1 or more antipsychotic prescriptions that were written by a psychiatrist (57.9% of young children, 71.9% of older children, 77.9% of adolescents, and 70.4% of young adults in 2010) ( Table 2) . However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010). Younger children treated with antipsychotics were proportionately the least likely of the 4 age groups to have filled 1 or more antipsychotic prescriptions from a psychiatrist.","[1.0, 5.0, 1.0, 3.0, 3.0]",Medicine,train,2.0,news,http://www.npr.org/sections/health-shots/2015/07/01/418935734/antipsychotics-too-often-prescribed-for-aggression-in-children
10.1038/s41598-018-20760-z,Medicine_15,"An AFM height image recorded 1 hour after SDS injection showed random unevenness on the surface, which indicates random adsorption of SDS molecules on the graphene surface.",This result indicates spontaneous random adsorption of the SDS molecules onto the graphene surface after the SDS solution injection.,"The development of a reliable method that enables the perfect alignment of molecules or molecular assemblies on a graphene surface may lead the way to tune the electric properties of graphene, and to improve the performance of graphene-based electronic devices. An AFM height image recorded 1 hour after SDS injection showed random unevenness on the surface, which indicates random adsorption of SDS molecules on the graphene surface. After 15 minutes of intense AFM scanning, the SDS adsorption morphology drastically changed and many ribbon-like molecules were observed.","The height of the graphene increased by ~2.5 nm overall, and aggregates of various size appeared (see Supplementary Fig. This result indicates spontaneous random adsorption of the SDS molecules onto the graphene surface after the SDS solution injection. The subsequent intense scanning with a large force between the tip and sample (see Methods) drastically modified the SDS adsorption morphology; the initially adsorbed SDS molecules were removed, and new patterned structures emerged on the surface (see Supplementary Movie S1, Supplementary Note 1, and Supplementary Fig.","[4.0, 5.0, 4.0, 5.0]",Medicine,train,4.5,news,http://ct.moreover.com/?a=33624582612&p=1pl&v=1&x=OROGVuUGDgkWIep8DYDL5w
10.1210/jc.2013-2350,Medicine_150,"Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants.","Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease.","Women who had PCOS also had a higher rate of endometrial cancer, or cancer of the lining of the uterus. Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants. A PCOS diagnosis also was associated with a higher risk of late onset diabetes, high blood pressure, heart disease, asthma and musculoskeletal disorders.","We suggest using the Rotterdam criteria for diagnosing PCOS (presence of two of the following criteria: androgen excess, ovulatory dysfunction, or polycystic ovaries). Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease. Thiazolidinediones have an unfavorable riskbenefit ratio overall, and statins require further study.","[2.0, 3.0, 2.0, 3.0, 2.0]",Medicine,train,2.4,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1111/cdep.12038,Medicine_151,"In fact, children who are spanked tend to become more aggressive over time, not less.",Spanking alone does not teach children why their behavior was wrong or what they should do instead .,"Overwhelming evidence

It's actually quite stunning that any parent today would use corporal punishment when the evidence overwhelmingly shows that this form of discipline is harmful, not helpful, to a child's development. In fact, children who are spanked tend to become more aggressive over time, not less. In addition, children who are spanked are at significantly greater risk of being physically abused.","It is difficult to imagine that a parent would be able to meet all these criteria when administering spanking; indeed, it would likely be both inadvisable and bordering on abusive if parents spanked children following every instance of a given misbehavior. Spanking alone does not teach children why their behavior was wrong or what they should do instead . Rather, it teaches them that they must behave when the threat of physical punishment exists, but once the threat is gone, they have no reason to behave appropriately .","[2.0, 3.0, 3.0, 3.0]",Medicine,train,2.75,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1038/s41467-018-05229-x,Medicine_152,"In a bulk solid, Wannier-Stark localization can only be maintained for an extremely short period of time, shorter than a single oscillation of infrared light.","Instead, they will be further excited to the energetically higher conduction and the lower valence bands, respectively, which will actually reduce their contribution to the bleaching of the optical absorption in the frequency range that is investigated here.","""This fundamental effect was predicted more than 80 years ago. In a bulk solid, Wannier-Stark localization can only be maintained for an extremely short period of time, shorter than a single oscillation of infrared light. Using the ultrafast laser systems at the University of Konstanz, Wannier-Stark localization has now been demonstrated for the first time.","In the experiment, the electron and hole occupations generated by an intense THz field will not stay in the lowest conduction and the highest valence bands. Instead, they will be further excited to the energetically higher conduction and the lower valence bands, respectively, which will actually reduce their contribution to the bleaching of the optical absorption in the frequency range that is investigated here. Thus the results obtained within the two-band model are expected to provide a lower estimate for the THz amplitude up to which Eq.","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1377/hlthaff.2012.1030,Medicine_154,"""The scale of this variation signals potential quality issues that should be quite alarming to women, clinicians, hospitals and policymakers,"" she added.Cesarean delivery is the most common surgery in the United States, performed on 1.67 million women each year.","43 State or federal public health agencies or licensing and accreditation boards can increase transparency and information availability through public reporting requirements for hospital cesarean delivery rates among lower-risk women, for example.","The variations we uncovered were striking in their magnitude, and were not explained by hospital size, geographic location, or teaching status,"" study lead author Katy Kozhimannil, an assistant professor at the university's School of Public Health, said in a school news release. ""The scale of this variation signals potential quality issues that should be quite alarming to women, clinicians, hospitals and policymakers,"" she added.Cesarean delivery is the most common surgery in the United States, performed on 1.67 million women each year. Cesarean rates increased from 20.7 percent in 1996 to 32.8 percent in 2011, according to the Minnesota researchers.","42 ▸ENHANCE PATIENT-CENTERED DECISION MAKING FOR MATERNITY CARE THROUGH PUBLIC REPORTING: Some pregnant women may face limited care options and lack full information on risks, benefits, and alternatives associated with medical care at the time of childbirth. 43 State or federal public health agencies or licensing and accreditation boards can increase transparency and information availability through public reporting requirements for hospital cesarean delivery rates among lower-risk women, for example. 45 In the case of obstetric care, such a strategy may be more promising as a result of rising public demand and the fact that pregnant women have many months to plan for and make decisions about childbirth care.","[2.0, 1.0, 1.0, 4.0, 1.0]",Medicine,train,1.8,news,http://www.webmd.com/baby/news/20130304/c-section-rates-vary-widely-at-us-hospitals
10.1038/s41598-018-30980-y,Medicine_155,"The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","predict ΔRecall 24-hr (B = −0.005, p = 0.983), nor was there a significant relationship between ΔRecall 24hr and the average SWA across both the nap and the overnight sleep bouts (B = −0.081, p = 0.936).","This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues. This delay may reflect ""short-term destabilization of an enriched memory,"" they add.","When children napped, it took them longer to Table 2 . predict ΔRecall 24-hr (B = −0.005, p = 0.983), nor was there a significant relationship between ΔRecall 24hr and the average SWA across both the nap and the overnight sleep bouts (B = −0.081, p = 0.936). In light of the reduced accuracy across the nap predicting improvements in accuracy overnight (Fig.","[1.0, 2.0, 2.0]",Medicine,train,1.6666666666666667,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1038/s41598-018-29793-w,Medicine_157,The discovery surprised even the longtime cold researchers who made it.,"Thus, microbiota at the time of infection may influence subsequent rhinovirus viral load.","The compositions also were found to correlate with viral load - the amount of cold virus inside the body. The discovery surprised even the longtime cold researchers who made it. ""The first surprise was that you can kind of identify these different buckets that people kind of fit into, and then the fact that the buckets seem to have some impact on how you respond to the virus and how sick you get was also interesting,"" said Ronald B. Turner, MD, of the University of Virginia School of Medicine.","Subjects with Ps/Mix cluster had significantly lower viral load than those subjects with Mor or Staph predominant microbiota types (Fig. Thus, microbiota at the time of infection may influence subsequent rhinovirus viral load. The results also suggest that high inflammatory response does not lead to low viral load as the subjects with Ps/Mix and Mor clusters had both relatively high inflammatory cytokine response and only Ps/Mix cluster had low viral load.","[1.0, 1.0, 3.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=37216978560&p=1pl&v=1&x=LVY7mDoQyN4rZ-ttzNExlg
10.1038/s41467-019-08382-z,Medicine_158,These interactions help Hel2 identify flaws in protein formation.,"This indicates reduced RNA-binding efficiency, particularly for Hel2 .","This clears the way for further proteins to be produced. These interactions help Hel2 identify flaws in protein formation. When researchers removed the parts of Hel2 in direct contact, this prevented the destruction of faulty proteins, showing that these contacts are important for the mechanism.","Despite this, total recovery of RNA in association with the mutant proteins was not increased in comparison to wild-type Hel2 ( Supplementary Tables 5-7) . This indicates reduced RNA-binding efficiency, particularly for Hel2 . In CRAC analyses, both truncation mutants showed substantially altered rRNA recovery, with reduced binding at the major site in 18S rRNA ( Fig.","[2.0, 4.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=38442592628&p=1pl&v=1&x=6qnjJlZN_F0RgmqDHnl0dA
10.1016/j.scitotenv.2019.04.266,Medicine_159,"""Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited un-intended consequences on more vulnerable communities,"" the authors write.","On a policy level, these aspects can appear as competing priorities between wildlife conservation, sustainable use, food safety, food security, and cultural aspects.","From questionnaires administered to both seller and buyers, the team found that most consumers bought bushmeat not because they needed the protein, but because they preferred the taste of it to livestock or they saw it as a healthier choice. ""Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited un-intended consequences on more vulnerable communities,"" the authors write. The study found that, in general, the threat of punishment for breaking Laos's laws controlling the trade in wild animals appeared to do little to dissuade vendors.","Therefore, it is clear that the hunting, trade, and consumption of wildlife are concurrently concerns for zoonotic disease transmission, significant sources of nutrients and/or livelihood for some communities, and major causes of biodiversity loss. On a policy level, these aspects can appear as competing priorities between wildlife conservation, sustainable use, food safety, food security, and cultural aspects. Given the flexibility of QRA methods such as Monte Carlo simulations, we further recommend their use as a tool for multi-disciplinary data integration for the evaluation of the multiple trade-offs of the bushmeat system.","[2.0, 1.0, 3.0, 1.0]",Medicine,train,1.75,news,http://ct.moreover.com/?a=39231575932&p=1pl&v=1&x=ugOkJg6MHSJ-5jXepqCzLA
10.1093/jee/tou026,Medicine_16,"After removing the bark from one of the trees, he found evidence that at least three generations of emerald ash borer larvae had used the tree, and he saw several live larvae that were actively feeding.","Removal of bark from one of these trees yielded evidence of three generations of usage by emerald ash borer, a dead adult, and live emerald ash borer larvae.","Fortunately, its damage has been limited to ash trees -- or so we thought. After removing the bark from one of the trees, he found evidence that at least three generations of emerald ash borer larvae had used the tree, and he saw several live larvae that were actively feeding. In addition, he found a dead adult that has been confirmed as emerald ash borer.","In total, 4 of the 20 mature white fringetrees I examined over this period showed symptoms of emerald ash borer attack. Removal of bark from one of these trees yielded evidence of three generations of usage by emerald ash borer, a dead adult, and live emerald ash borer larvae. Some of the other trees I examined may have contained feeding larvae for the first time in 2014 and whose damage was not yet apparent externally.","[3.0, 5.0, 5.0, 5.0]",Medicine,train,4.5,news,http://www.sciencedaily.com/releases/2015/01/150115102827.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1186/s40168-015-0071-z,Medicine_160,The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota.,"At first glance, it appeared as if there were no species-level differences in the bifidobacterial populations of secretorfed and non-secretor-fed infants ( Figure 11 ).","The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors. The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota. The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother.","In addition, of the two isolates obtained from non-secretor-fed infants that could grow on 2FL, one was a Bifidobacterium dentium strain, a species adapted to oral niches . At first glance, it appeared as if there were no species-level differences in the bifidobacterial populations of secretorfed and non-secretor-fed infants ( Figure 11 ). However, a difference was noted between secretor-fed infants and non-secretor-fed infants in which bifidobacterial species were present in high relative abundances when compared to the microbiota as a whole.","[2.0, 5.0, 2.0, 4.0, 4.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/science.1252496,Medicine_162,"""These particles are so precious.","The observed impact density of nonterrestrial materials on the foils is 0.8 cm −2 , and thus the fraction of impacts of interplanetary origin is estimated to be 0.17/0.8 = 0.2.","While the samples are suspected to be from beyond the solar system, he says, potential confirmation of their origin must come from subsequent tests that will ultimately destroy some of the particles. ""These particles are so precious. We have to think very carefully about what we do with each particle.""","Although the trajectories of the four foil interstellar candidates are unknown, statistical arguments based on trajectories still apply. The observed impact density of nonterrestrial materials on the foils is 0.8 cm −2 , and thus the fraction of impacts of interplanetary origin is estimated to be 0.17/0.8 = 0.2. This value is in good agreement with the preflight estimates of Landgraf et al.","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.nanowerk.com/news2/space/newsid=37140.php
10.1111/1365-2656.12871,Medicine_163,"""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus.","These suggestions are speculative, and not mutually exclusive, but could be a starting point for examining why rabbits challenged with MYXV have survival rates similar to susceptible animals.","It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked."" ""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","Another possible explanation is that exposure to MYXV compromises the health of rabbits in such a way that it reduces the survival of individuals subsequently infected by RHDV. These suggestions are speculative, and not mutually exclusive, but could be a starting point for examining why rabbits challenged with MYXV have survival rates similar to susceptible animals. When interpreting these results, it is important to consider that the odds ratios of the survival of susceptible and immune rabbits (i.e., those surviving infection) do not provide precise estimates of infection-induced mortality rates.","[2.0, 4.0, 3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1038/s41598-018-29793-w,Medicine_164,Each nasal microbiota type had a characteristic inflammatory response and viral load profile.,Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation.,"The study team found that the baseline nasal microbiota samples divided into six types named after predominant bacterial genera: (1) Staphylococcus, (2) Corynebacterium/Alloiococcus, (3) Moraxella, (4) Haemophilus, (5) Pseudomonadaceae/Mixed, and (6) Mixed. Each nasal microbiota type had a characteristic inflammatory response and viral load profile. In general, subjects having Staphyloccocus, and Corynebacterium/Alloiococcus types had lower inflammatory responses and Pseudomonadaceae/Mixed type had lower viral load than other types.","The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection. Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation. We further found that rhinovirus infection did not have a major impact on the nasal microbiota.","[3.0, 3.0, 3.0, 2.0]",Medicine,train,2.75,news,http://ct.moreover.com/?a=37212363335&p=1pl&v=1&x=sLcdfRtU-o1Jl6n2DiKDzQ
10.1001/jamapsychiatry.2015.0500,Medicine_165,"This study, which may be the broadest look yet at use of antipsychotics in children, found that most children had not been diagnosed with a mental disorder before being given antipsychotics.","After several years of increasing rates of antipsychotic treatment of children and adolescents in the United States, the rate of antipsychotic use among children decreased between 2008 and 2010.","Boys were more likely to be given the medications. This study, which may be the broadest look yet at use of antipsychotics in children, found that most children had not been diagnosed with a mental disorder before being given antipsychotics. ADHD was the most common diagnosis, applied to 52.5 percent of young children, 60 percent of older children, and 34.9 percent of teenagers diagnosed with ADHD.","Fourth, service claims data were available only for a subset of patients. After several years of increasing rates of antipsychotic treatment of children and adolescents in the United States, the rate of antipsychotic use among children decreased between 2008 and 2010. In view of evidence of widespread antipsychotic prescribing outside of US Food and Drug Administration-labeled indications and concerns regarding the adverse metabolic effects of second-generation antipsychotics, 49 this decline is a welcome development.","[3.0, 2.0, 2.0]",Medicine,train,2.333333333333333,news,http://www.npr.org/sections/health-shots/2015/07/01/418935734/antipsychotics-too-often-prescribed-for-aggression-in-children
10.1038/s41467-018-07557-4,Medicine_166,"There's No Silver Lining

To make matters worse, the study also notes that these drastic changes will still happen even if the world decreases its carbon emission significantly.","With respect to the decades following 2050, however, attainment of the goals of the Paris Agreement's climate warming target (i.e., holding global warming to well below 2°C above preindustrial levels and pursuing efforts to limit the temperature increase to 1.5°C) 29 would make a clear difference in terms of potential damage to infrastructure ( Fig.","There's No Silver Lining

To make matters worse, the study also notes that these drastic changes will still happen even if the world decreases its carbon emission significantly. The new findings revealed ""an unprecedentedly high spatial resolution"" perspective of how permafrost will jeopardize infrastructure. The findings also showed that one-third of all Arctic infrastructure rests on a piece of land that is highly likely to thaw by 2050.","This result is congruent with projected changes in the Arctic 1 , and emphasizes the need for adaptation-based policies at community and regional levels in the near future. With respect to the decades following 2050, however, attainment of the goals of the Paris Agreement's climate warming target (i.e., holding global warming to well below 2°C above preindustrial levels and pursuing efforts to limit the temperature increase to 1.5°C) 29 would make a clear difference in terms of potential damage to infrastructure ( Fig. Considering the uncertainty embedded in the projections of ground temperature and annual thaw depth, the quantity of infrastructure potentially under risk is probably not considerably smaller (lower limit), but could be substantially larger (upper limit) than estimated ( Fig.","[1.0, 1.0, 2.0]",Medicine,train,1.3333333333333333,news,http://ct.moreover.com/?a=37967333906&p=1pl&v=1&x=ltio0H7-Rr6r3LuvSX7DEA
10.1093/chemse/bjt066,Medicine_167,"In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label.","Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis.","""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","These findings further strengthen the concept that odor perception is influenced by cognitive interpretation. Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis. We found that participants rated geraniol as more intense when it was labeled positively (""fresh flowers"") than when labeled negatively (""cheap perfume"").","[2.0, 4.0, 1.0, 4.0]",Medicine,train,4.0,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1007/s13524-014-0321-x,Medicine_168,"Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents.","We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has.","Those who have children at an older age or who are more educated have a particularly positive response to a first birth. Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.","Importantly, we observe that happiness increases before birth, suggesting that the happiness gain around the time of birth may capture not only the effect of the birth but also the complex childbearing process that may involve partnership formation, partnership quality, and increased sexual activity. We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has. These results were similar in Britain and Germany.","[2.0, 5.0, 3.0, 3.0]",Medicine,train,3.25,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2013.3172,Medicine_169,"Bauch said that as this trend continues, people will come to find themselves in a situation where vaccination coverage has declined and populations are more susceptible to disease.","Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels.","Although pediatric vaccination is mandatory across most of North America's public school, the researchers report that the number of parents applying for their children to be exempt from vaccination requirements is on the rise. Bauch said that as this trend continues, people will come to find themselves in a situation where vaccination coverage has declined and populations are more susceptible to disease. ""Parents are not cold, clinical rationalists who base their decisions only on data.","The social learning rate k can also influence whether the population converges to no vaccine coverage or returns to full vaccine coverage, after a vaccine scare (figure 5). Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels. This is obvious in comparisons of the fitted model appearing in figure 1e,f to simulations of the same model, but where the pertussis vaccine scare never occurred (s ¼ 1, figure 6 ).","[3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://www.natureworldnews.com/articles/6038/20140214/vaccine-scares-perpetrate-below-optimal-coverage-spread-infectious-diseases.htm
10.1210/jc.2013-2350,Medicine_17,Researchers analyzing the data found women who were diagnosed with PCOS were more likely to be hospitalized for reasons unrelated to reproductive health or injury than their counterparts.,We suggest no specific interventions for prevention of PCOS in offspring of women with PCOS (2͉QEEE).,"Additional health care resources should be directed to address the risks facing this population."" Researchers analyzing the data found women who were diagnosed with PCOS were more likely to be hospitalized for reasons unrelated to reproductive health or injury than their counterparts. Women who had PCOS were more likely to have miscarriages, ectopic pregnancies or other gynecological conditions such as irregular menstrual periods and endometriosis.",Whether these increased risks are due to PCOS itself or the features associated with PCOS such as IR or obesity requires further study. We suggest no specific interventions for prevention of PCOS in offspring of women with PCOS (2͉QEEE). Androgen levels may be increased in pregnant women with PCOS .,"[2.0, 1.0, 1.0]",Medicine,train,1.3333333333333333,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1002/ijc.31746,Medicine_170,"""We found that small genetic changes to the ANO7 gene increase a patient's risk of aggressive prostate cancer.","In our study, higher ANO7 mRNA expression strongly correlated with poor overall survival in PrCa patients.","They were particularly interested in studying mutations to the ANO7 gene because their previous research suggested this could be a gene of interest for prostate cancer. ""We found that small genetic changes to the ANO7 gene increase a patient's risk of aggressive prostate cancer. Genetic testing for ANO7 could help identify these patients sooner and may bring new opportunities for precision oncology in prostate cancer,"" says the leading author of the study, Professor Johanna Schleutker from the Institute of Biomedicine of the University of Turku, Finland.","on the other hand, reported high individual variability of ANO expression between individual samples, both in terms of absolute expression levels and of expression level ratios between matched normal and tumorous prostate. In our study, higher ANO7 mRNA expression strongly correlated with poor overall survival in PrCa patients. Multivariate analysis compared high and low ANO7 expression and showed an even stronger negative survival effect than the model with the three selected SNPs, indicating that there might be additional variants that regulate expression.","[4.0, 5.0, 5.0, 4.0, 4.0]",Medicine,train,4.4,news,http://ct.moreover.com/?a=34961246227&p=1pl&v=1&x=fiF8OmDGvWhClXOSUOnd9w
10.1073/pnas.1515528113,Medicine_171,"""The greatest benefits of HPV vaccination both in terms of cancer reduction and health care costs are realized when policy promoting vaccination is coordinated across states,"" said Alison Galvani, the Burnett and Stender Families Professor of Epidemiology and director of CIDMA.","Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine.","In addition, efforts to expand HPV vaccination, particularly in states with low coverage, could prevent even more cancers and deaths, said the researchers, adding that due to interstate migration, all states would benefit if they aligned vaccination policy. ""The greatest benefits of HPV vaccination both in terms of cancer reduction and health care costs are realized when policy promoting vaccination is coordinated across states,"" said Alison Galvani, the Burnett and Stender Families Professor of Epidemiology and director of CIDMA. Furthermore, increased funding to states could improve vaccine coverage and public health, the researchers noted.","Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders. Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine. Both of these vaccines are highly efficacious against HPV-16 and HPV-18 and are partially efficacious against other non-vaccine-targeted oncogenic serotypes .","[4.0, 4.0, 3.0, 5.0]",Medicine,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/tL7ylLtvSRo/
10.1001/jamapsychiatry.2015.0500,Medicine_173,"Performing the most extensive analysis of antipsychotic use among children and adolescents of its kind, the study authors found that drugs normally recommended for the treatment of mental illnesses like schizophrenia and bipolar disorder are often being given to children and teens suffering from self-limiting behavioral dysfunctions or conditions like Attention-deficit/hyperactivity disorder.",This age profile refines earlier reports of steadily increasing rates of antipsychotic use across multiyear developmental categories of childhood to adolescence 28 to early adulthood.,"Performing the most extensive analysis of antipsychotic use among children and adolescents of its kind, the study authors found that drugs normally recommended for the treatment of mental illnesses like schizophrenia and bipolar disorder are often being given to children and teens suffering from self-limiting behavioral dysfunctions or conditions like Attention-deficit/hyperactivity disorder. ""What's especially important is the finding that around 1.5 percent of boys aged 10-18 are on antipsychotics, and then this rate abruptly falls by half, as adolescents become young adults."" Boys were more likely than girls to be prescribed these drugs, and the researchers were encouraged that, overall, antipsychotic use among children has slightly dropped from 2008 to 2010.","There was a rise in antipsychotic use during childhood that extended into adolescence for females, followed by a plateau and a decline during the transition to early adulthood. This age profile refines earlier reports of steadily increasing rates of antipsychotic use across multiyear developmental categories of childhood to adolescence 28 to early adulthood. 29 A peak in antipsychotic use among males aged 11 to 17 years fits with treatment of conduct problems that commonly occur during adolescence.","[3.0, 3.0, 3.0, 1.0, 2.0]",Medicine,train,2.4,news,http://www.medicaldaily.com/antipsychotics-are-being-given-kids-temporary-behavioral-problems-adhd-341188
10.1016/j.cell.2016.09.056,Medicine_174,The second surprise came with the unearthing of CD81's inner cavity and the discovery that it can hold a cholesterol molecule.,"The tetraspanin CD81 contains a large intramembrane cavity occupied by cholesterol, indicating the potential for functional modulation by small molecules.","""It's different from all prior predictions,"" said Blacklow. The second surprise came with the unearthing of CD81's inner cavity and the discovery that it can hold a cholesterol molecule. That got the team especially excited, because it revealed that researchers can now try to manipulate CD81 using cholesterol or other small molecules.","Cholesterol binding appears to modulate CD81 activity in cells, suggesting a potential mechanism for regulation of tetraspanin function. The tetraspanin CD81 contains a large intramembrane cavity occupied by cholesterol, indicating the potential for functional modulation by small molecules. The development of specialized cell-cell interactions and new cell types likely selected for the duplication and differentiation of tetraspanins that evolved to effect specific functions.","[4.0, 4.0, 4.0]",Medicine,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ay74vlkGcfw/
10.1038/s41467-018-07557-4,Medicine_175,"""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper.","Detrimental effects on engineered structures, socio-economic activities, and natural systems can, therefore, all be expected throughout the permafrost domain under climate warming 1 , particularly in high-risk areas with substantial urban and industrial centres such as Vorkuta and Novyi Urengoy in hot spots of infrastructure hazard in the Russian Arctic ( Fig.","The team found that 3.6 million people--three quarters of the current population in the Northern Hemisphere permafrost area--may be affected by infrastructure damage from permafrost thaw. ""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper. The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports.","The potential harm to industrial facilities could be larger than estimated (pipelines: estimate = 32%, range = 24-70%; industrial areas: estimate = 25%, range = 20-64%) ( Fig. Detrimental effects on engineered structures, socio-economic activities, and natural systems can, therefore, all be expected throughout the permafrost domain under climate warming 1 , particularly in high-risk areas with substantial urban and industrial centres such as Vorkuta and Novyi Urengoy in hot spots of infrastructure hazard in the Russian Arctic ( Fig. adaptation strategies and structures such as insulation and thermosyphons that were not considered in this pan-Arctic study) can to some extent address both human-induced and naturally caused problems, their economic cost may be prohibitive at regional scales 32 .","[3.0, 4.0, 2.0, 3.0, 2.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=37952323296&p=1pl&v=1&x=YZkcSHKHdqhjfYYiUvZ_gw
10.1016/j.ijnurstu.2014.02.007,Medicine_177,"Recent catastrophic failures such as events at Mid-Staffordshire have highlighted the importance of staffing levels to patient survival, and this study has reinforced that message.""",The estimated magnitude of these effects is similar to the corresponding estimates of their effects on the risk of mortality in the ICU.,"Professor Elizabeth West, pictured, who led the research, says: ""This is timely because the public are concerned about the ability of the NHS to provide safe and compassionate care. Recent catastrophic failures such as events at Mid-Staffordshire have highlighted the importance of staffing levels to patient survival, and this study has reinforced that message."" This is the first study of patient survival in ICUs to look at the numbers of doctors as well as nurses.","Again, the number of nurses and the number of consultants per bed have a negative association with the risk of mortality. The estimated magnitude of these effects is similar to the corresponding estimates of their effects on the risk of mortality in the ICU. However, although both main effects are statistically significant, this is not true of either of the two estimated interaction effects.","[2.0, 1.0, 2.0, 3.0, 5.0]",Medicine,train,2.0,news,http://www.healthcanal.com/public-health-safety/49249-low-icu-staffing-levels-affect-patient-survival.html
10.1001/jamaoncol.2018.0798,Medicine_18,"""Our findings underscore the importance of a thorough FDA review of new cancer therapies,"" said Cary Gross, M.D., senior author, YSM professor of medicine, and a member of Yale Cancer Center.","Overall, similar proportions of older and younger patients received anti-PD-1 treatment during the first 9 months after FDA approval.","The study results also concern the researchers because new therapies are being approved when questions remain about their risks and benefits. ""Our findings underscore the importance of a thorough FDA review of new cancer therapies,"" said Cary Gross, M.D., senior author, YSM professor of medicine, and a member of Yale Cancer Center. ""We found that the standard of care can change virtually overnight, when a new drug is brought to market.","Within 4 months after FDA approval, greater than 60% of eligible patients in each cohort had received anti-PD-1 treatment. Overall, similar proportions of older and younger patients received anti-PD-1 treatment during the first 9 months after FDA approval. However, there were significant differences in age between clinical trial participants and patients receiving anti-PD-1 treatment in clinical practice, with more patients being older than 65 years in clinical practice (range, 327 of 1365 [60.6%] CONCLUSIONS AND RELEVANCE Anti-PD-1 agents rapidly reached patients in clinical practice, and patients treated in clinical practice differed significantly from patients treated in pivotal clinical trials.","[1.0, 2.0, 1.0, 2.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=34024686802&p=1pl&v=1&x=V7M9zzFOhn6CjXB9WZIACw
10.3945/jn.113.188441,Medicine_181,"""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption.""","However, the stronger association between instant noodle consumption $2 times/wk and metabolic syndrome among women after excluding participants taking blood pressure-lowering and lipid-lowering medications or who had a history of diabetes mellitus might indicate the robustness of that association.","""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said. ""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption."" Dr. Shin added that the study's health implications could be substantial -- particularly if it leads to people choosing healthier foods.","First, we cannot infer a causal relation given our cross-sectional study design. However, the stronger association between instant noodle consumption $2 times/wk and metabolic syndrome among women after excluding participants taking blood pressure-lowering and lipid-lowering medications or who had a history of diabetes mellitus might indicate the robustness of that association. Second, dietary pattern construction by principal components analysis may be limited by subjectivity in the proper number of extracted factors and food-grouping methods .","[2.0, 2.0, 3.0, 2.0, 2.0]",Medicine,train,2.2,news,http://www.sciencedaily.com/releases/2014/08/140812121642.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1146/annurev-publhealth-031914-122421,Medicine_182,"""As the Latino population continues to grow, it should be a national health policy priority to improve their access to care and determine the best way to deliver high-quality care to this population at the local, state and national levels,"" Ortega said.",Focusing on efforts to improve delivery systems for Latinos will likely reduce disparities in patients' experiences and the quality of primary care received.,"The need to increase the number of Latino physicians and non-physician health care providers to address language and cultural barriers. ""As the Latino population continues to grow, it should be a national health policy priority to improve their access to care and determine the best way to deliver high-quality care to this population at the local, state and national levels,"" Ortega said. ""Resolving these four key issues would be an important first step.""","Differences in the quality of care appear to be largely attributable to the fact that Latinos are cared for in settings where communication and the quality of care are not especially patient-centered . Focusing on efforts to improve delivery systems for Latinos will likely reduce disparities in patients' experiences and the quality of primary care received. Importantly, Latinas, in general, tend to have worse diet-related behaviors when compared with non-Latinas, including consuming more fast food, sugar-sweetened beverages, and fried potatoes .","[3.0, 2.0, 2.0]",Medicine,train,2.333333333333333,news,http://www.sciencedaily.com/releases/2015/03/150319092222.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29
10.1038/s41598-018-30980-y,Medicine_183,"""This study demonstrates that napping is beneficial to memory processing,"" they point out.","Only of the 20 children with PSG reached REM in their nap (M% REM = 2.5%, SD = 4.51%).","As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","However, we were able to determine sleep latency on all 4, and REM latency on 2 of the unscorable wake night records, as the recording issues did not occur until later in the night. Only of the 20 children with PSG reached REM in their nap (M% REM = 2.5%, SD = 4.51%). For those children who reached REM sleep during their naps, REM comprised only 8.11% (SD = 4.38) of the nap.","[3.0, 3.0, 1.0, 3.0, 1.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1093/chemse/bjt066,Medicine_185,"""Moreover, this is the first time we have been able to influence the edibility perception of an odour, even though the positive and negative labels accompanying the odours showed non-food words,"" adds Frasnelli.","Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis.","""It shows that odour perception is not objective: it is affected by the cognitive interpretation that occurs when one looks at a label,"" says Manescu. ""Moreover, this is the first time we have been able to influence the edibility perception of an odour, even though the positive and negative labels accompanying the odours showed non-food words,"" adds Frasnelli. This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process.","These findings further strengthen the concept that odor perception is influenced by cognitive interpretation. Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis. We found that participants rated geraniol as more intense when it was labeled positively (""fresh flowers"") than when labeled negatively (""cheap perfume"").","[3.0, 1.0, 3.0]",Medicine,train,2.333333333333333,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1073/pnas.1414221111,Medicine_186,"In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours.",These morphological changes reach a maximum by 7-8 h after treatment.,"In this study, researchers determined that (+)-SJ733 uses a novel mechanism to kill the parasite by recruiting the immune system to eliminate malaria-infected red blood cells. In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours. After 48 hours the parasite was undetectable.","This immediate response triggers other cellular responses, probably including the arrest of protein synthesis , and these are integrated at the level of both the parasite (manifested as a swollen, development-arrested phenotype) and the host erythrocyte (manifested as induction of an eryptotic/senescent phenotype). These morphological changes reach a maximum by 7-8 h after treatment. In vivo, these effects trigger rapid clearance of the infected, treated erythrocytes through host-mediated mechanisms used to clear aging red cells.","[2.0, 1.0, 2.0]",Medicine,train,1.6666666666666667,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1038/s41551-018-0317-8,Medicine_188,AKI mice treated with rectangular DONs displayed improved kidney excretory function comparable to mice receiving treatment using the mainline drug NAC.,64 Cu-Rec-DON showed rapid accumulation in the kidneys as early as 5 min post-injection ( Fig.,"Examination of stained tissue samples further confirmed the beneficial effects of the DONs in the kidney. AKI mice treated with rectangular DONs displayed improved kidney excretory function comparable to mice receiving treatment using the mainline drug NAC. Results showed the DONs were non-immunogenetic and tissue staining of heart, liver, spleen lungs and kidney revealed their low toxicity in primary organs, making them attractive candidates for clinical use in humans.","37 ). 64 Cu-Rec-DON showed rapid accumulation in the kidneys as early as 5 min post-injection ( Fig. 3c ) in AKI mice suggested that the injured kidneys may still extract and excrete DONs from the blood pool into the bladder, although at a decreased rate.","[4.0, 2.0, 2.0, 1.0, 2.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=37636191811&p=1pl&v=1&x=qc3pI9OOn-ja-gCCneNC8w
10.1038/s41467-018-07557-4,Medicine_189,"Concluding, the researchers say a detailed infrastructure risk assessment is needed to understand how communities in permafrost areas will be affected as the planet warms.","Here, the ground temperature and thaw of near-surface permafrost was considered to be the most important factor affecting infrastructure hazard followed by GIC, relative increase of ALT, fine-grained sediment content and slope gradient.","[To prevent the permafrost thawing], we need to stop climate warming."" Concluding, the researchers say a detailed infrastructure risk assessment is needed to understand how communities in permafrost areas will be affected as the planet warms. He told Newsweek the part of the paper looking at Canada uses incorrect permafrost projections, while they use a statistical approach to predict ground temperature--which Burn says does not provide an accurate representation of risk.","The AHP developed is a multi-objective, multicriteria decision-making approach to analyse complicated problems such as the determination of relative roles of factors affecting geohazards 70 . Here, the ground temperature and thaw of near-surface permafrost was considered to be the most important factor affecting infrastructure hazard followed by GIC, relative increase of ALT, fine-grained sediment content and slope gradient. 2).","[3.0, 5.0, 1.0, 2.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=37952048427&p=1pl&v=1&x=WVBbJHZ_CDGkehwcKPFvdQ
10.1016/j.psyneuen.2016.08.027,Medicine_19,The research follows an earlier study which suggested that elevated long-term levels of cortisol may reduce the likelihood of a successful outcome for patients trying to conceive by IVF.,"Despite these potential limitations, the present study extends the available evidence for the role of cortisol on clinical pregnancy in IVF patients and provides the first evidence that elevated chronic cortisol levels are associated with a reduced likelihood of pregnancy.","The research follows an earlier study which suggested that elevated long-term levels of cortisol may reduce the likelihood of a successful outcome for patients trying to conceive by IVF. However, many factors influence cortisol (including physical activity, sleep and some aspects of our diet such as caffeine) and so it is possible that any or all of these factors may account for the effects of cortisol on pregnancy."" If this is proven with further solid research it may modify our approach to pre-IVF testing in all patients.","It is also not clear how generalizable our results are to women trying to conceive naturally; also our findings extend only to clinical pregnancy. Despite these potential limitations, the present study extends the available evidence for the role of cortisol on clinical pregnancy in IVF patients and provides the first evidence that elevated chronic cortisol levels are associated with a reduced likelihood of pregnancy. Thus, further research is needed to not only corroborate these findings but also identify the pathways.","[3.0, 5.0, 5.0, 5.0, 4.0]",Medicine,train,4.4,news,http://ct.moreover.com/?a=33739698938&p=1pl&v=1&x=AcVA0Y4hatHNh4-L_5fqfA
10.1016/j.jpain.2017.11.005,Medicine_191,"Acupuncture was similarly effective for each of these conditions, his study found.",Another novel finding is the higher than average effects of acupuncture on upper body musculoskeletal pain.,"""If our study had been on a drug, we'd say the drug works--there's a statistically significant effect there,"" says Andrew Vickers, first author of that study and a biostatistician at Memorial Sloan Kettering Cancer Center in New York City. Acupuncture was similarly effective for each of these conditions, his study found. Also, acupuncture's benefits were durable: After a year of treatment, the average patient reported only a minor drop it its efficacy.","In some cases, heterogeneity was also driven by a set of outlying trials with large effect sizes. Another novel finding is the higher than average effects of acupuncture on upper body musculoskeletal pain. We now have sufficient data to conduct a meta-analysis for neck pain and for shoulder pain, even after exclusion of outlying trials.","[2.0, 2.0, 3.0, 3.0, 4.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=38497695155&p=1pl&v=1&x=s_16A13LceP0QMt7V7o-QA
10.1016/j.cell.2018.04.034,Medicine_192,"This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy,"" says senior study author Arul Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology.",CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ).,"The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant. This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy,"" says senior study author Arul Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology. Researchers found loss of CDK12 in only about 1 percent of early prostate cancer samples.","However, our data, and the observations made previously in CDK12 mutant ovarian tumors , are inconsistent with that model. CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ). Overall, the genomic phenotypes of HR and CDK12 deficiency are clearly distinct.","[1.0, 2.0, 3.0, 2.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1152/ajpregu.00204.2013,Medicine_194,"A new study using an animal model to mimic key effects of PE in humans, and led by Graeme Smith of Queen's University, Canada, may help explain the lower incidence of PE in some smokers.",There are other potential beneficial effects of both HO-1 and CO in placental development and fetal survival.,"A new study using an animal model to mimic key effects of PE in humans, and led by Graeme Smith of Queen's University, Canada, may help explain the lower incidence of PE in some smokers. The study also suggests a therapy that could offer similar protection against PE with none of smoking's well-known risks. Although toxic at high levels, low levels of CO are produced naturally by the body and have positive effects.","Our study did not evaluate the effect of CO on placental oxidative stress, and future work should aim to report on these findings. There are other potential beneficial effects of both HO-1 and CO in placental development and fetal survival. It would make sense then, that increasing one's CO levels could rescue some of the deleterious effects associated with PE.","[1.0, 1.0, 3.0]",Medicine,train,1.6666666666666667,news,http://www.sciencedaily.com/releases/2013/09/130919154253.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1210/en.2015-2036,Medicine_195,"In particular, we show that vitamin D deficiency directly results in an increase in the expression of a gene (called ID1) that promotes breast cancer metastasis.",We found that vitamin D-deficient mice developed mammary tumors that were palpable an average of 7 days earlier than control mice.,"It is important to note that the research recommends avoiding deficiency which does not mean that taking more vitamin D than needed is beneficial. In particular, we show that vitamin D deficiency directly results in an increase in the expression of a gene (called ID1) that promotes breast cancer metastasis. Indeed, we found that this relationship between vitamin D levels in the whole body and ID1 levels in the tumor was present in human patients at the time of their diagnosis.","Ingestion of the LD25 diet caused a statistically significant decrease in serum 25(OH)D levels compared with control mice (Supplemental Figure 1) . We found that vitamin D-deficient mice developed mammary tumors that were palpable an average of 7 days earlier than control mice. Importantly, vitamin D deficiency also accelerated tumor growth, resulting in a significant increase in the mean tumor volume after 6 weeks compared with tumors grown in mice fed the control diet ( Figure 1A ).","[5.0, 4.0, 4.0, 4.0, 4.0]",Medicine,train,4.2,news,http://www.theepochtimes.com/n3/1987536-vitamin-d-deficiency-promotes-breast-cancer-growth-in-mice/
10.1001/jamapsychiatry.2015.0500,Medicine_196,"It's also not necessarily strange that these drugs were used in cases where the child had no mental health diagnosis, though it could suggest overuse.","There were approximately 270 000 antipsychotic prescriptions dispensed to younger children, 2.14 million to older children, 2.80 million to adolescents, and 1.83 million to young adults nationwide in 2010.","But because of the unknown risks that come with flooding a maturing brain with these drugs, they should be utilized only when it's absolutely necessary. It's also not necessarily strange that these drugs were used in cases where the child had no mental health diagnosis, though it could suggest overuse. The authors hope that their findings will prompt others to develop better, safer approaches to treating these serious but manageable conditions.","The age and sex composition of the IMS population that filled at least 1 prescription of any kind closely resembled the composition of the corresponding population from the nationally representative Medical Expenditure Panel Survey. There were approximately 270 000 antipsychotic prescriptions dispensed to younger children, 2.14 million to older children, 2.80 million to adolescents, and 1.83 million to young adults nationwide in 2010. Across the 4 age groups, almost all of the antipsychotic prescriptions (96.7%) were for secondgeneration medications.","[2.0, 2.0, 1.0, 2.0, 2.0]",Medicine,train,1.8,news,http://www.medicaldaily.com/antipsychotics-are-being-given-kids-temporary-behavioral-problems-adhd-341188
10.1073/pnas.1509654112,Medicine_197,"But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains.","Here we show that, although there are sex/gender differences in brain and behavior, humans and human brains are comprised of unique ""mosaics"" of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males.","They found 29 regions that seem to be different sizes in people who identified as male or female. But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains. While itaEUR(tm)s possible to have predominantly female components or predominantly male components to your brain, researchers found that most people are in the middle.","Such an alignment may be predicted by the classic view of sexual differentiation of the brain, according to which masculinization and defeminization of the brain are under the sole influence of testosterone (9). Here we show that, although there are sex/gender differences in brain and behavior, humans and human brains are comprised of unique ""mosaics"" of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males. Our results demonstrate that regardless of the cause of observed sex/gender differences in brain and behavior (nature or nurture), human brains cannot be categorized into two distinct classes: male brain/female brain.","[3.0, 4.0, 2.0, 4.0, 4.0]",Medicine,train,3.4,news,http://healthmedicinet.com/news/science-proves-men-and-women-are-actually-from-the-same-planet/
10.1001/jama.2018.20578,Medicine_198,"Compared with no aspirin, aspirin use correlated with significant reductions in the composite cardiovascular outcome (57.1 versus 61.4 per 10,000 participant-years; hazard ratio, 0.89; absolute risk reduction, 0.38 percent) and correlated with an increased risk for major bleeding events (23.1 versus 16.4 per 10,000 participant-years; hazard ratio, 1.43; absolute risk increase, 0.47 percent).","While the reduction in cancer mortality emerged after at least 5 years of follow-up, this result was not replicated in the ASCEND trial that followed up 480 participants with diabetes for a mean of 7.4 years.","The researchers found that the median baseline risk for the primary cardiovascular outcome (composite of cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke) was 9.2 percent. Compared with no aspirin, aspirin use correlated with significant reductions in the composite cardiovascular outcome (57.1 versus 61.4 per 10,000 participant-years; hazard ratio, 0.89; absolute risk reduction, 0.38 percent) and correlated with an increased risk for major bleeding events (23.1 versus 16.4 per 10,000 participant-years; hazard ratio, 1.43; absolute risk increase, 0.47 percent). The meta-analysis ""demonstrates a general consistency of the newer studies with the previous studies of aspirin for primary prevention of cardiovascular events,"" write the authors of an accompanying editorial.","This finding is in contrast to an individual patient data meta-analysis of primary and secondary prevention aspirin trials that demonstrated a % reduction in cancer mortality associated with aspirin use. While the reduction in cancer mortality emerged after at least 5 years of follow-up, this result was not replicated in the ASCEND trial that followed up 480 participants with diabetes for a mean of 7.4 years. The findings of this study suggest that the association of aspirin with cancer outcomes is neutral, with no suggestion of harm or benefit from the available current evidence.","[1.0, 2.0, 1.0, 1.0]",Medicine,train,1.25,news,http://ct.moreover.com/?a=38331905067&p=1pl&v=1&x=XtWX8D8AaSJygxxptr_VHw
10.1073/pnas.1403984111,Medicine_199,"""It is obvious that stemming the rate of illegal killing is paramount,"" the researchers conclude.",This threshold PIKE value can serve as a rule of thumb indicating excessive pressure that requires intervention if the corresponding population is to avoid extirpation.,"And as the map above shows, that varies from country to country. ""It is obvious that stemming the rate of illegal killing is paramount,"" the researchers conclude. ... [C]urbing demand -- particularly in the Far East -- appears necessary to reduce black market ivory prices and alleviate the unsustainable pressure from illegal killing on wild populations.""","Simulation results given our demographic parameterization indicated populations with PIKE of 0.54 were likely at equilibrium, with higher proportions associated with greater probabilities of decline ( Fig. This threshold PIKE value can serve as a rule of thumb indicating excessive pressure that requires intervention if the corresponding population is to avoid extirpation. The two approaches implemented in our broad-scale analysis provided similar results when contrasted at the regional or continental scales, but relied on starkly different data (a limited empirical sample from well-monitored populations versus a coarse-scale model that provides predictions on all elephant populations across Africa).","[1.0, 1.0, 1.0, 2.0]",Medicine,train,1.25,news,http://www.vox.com/2014/8/20/6045505/more-than-100000-african-elephants-have-been-killed-by-poachers-since
10.1038/s41598-018-30980-y,Medicine_2,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.",Yet nap slow wave activity also predicted greater overnight improvement in memory.,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.",Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory. These results suggest that sleep bouts can interact to benefit memory in early childhood.,"[4.0, 2.0, 1.0, 3.0, 3.0]",Medicine,train,2.6,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1038/s41598-018-25573-8,Medicine_20,"""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor.",Histological analysis revealed P53 complete loss in invasive carcinoma and intraepithelial carcinoma; and strongly (contiguous) positive in other areas.,"In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered,"" write the investigators. ""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles.","Moreover, malignant cells were present, consistent with adenocarcinoma (CK7+/CK20-/CDX-2-/CA-125+). Histological analysis revealed P53 complete loss in invasive carcinoma and intraepithelial carcinoma; and strongly (contiguous) positive in other areas. Ki67 was elevated in invasive carcinoma and intraepithelial carcinoma (10-20%); low in other areas.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1016/j.stemcr.2018.03.019,Medicine_200,X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.,This analysis further defined the dynamic regulation of DNA methylation with single-CpG resolution within enhancers during female reprogramming and revealed expected as well as unexpected single-CpG-level DNA methylation changes.,"Note: material may have been edited for length and content. For further information, please contact the cited source. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.","This analysis enabled us to assess changes in DNA methylation at single CpG resolution, which could be masked in averages. This analysis further defined the dynamic regulation of DNA methylation with single-CpG resolution within enhancers during female reprogramming and revealed expected as well as unexpected single-CpG-level DNA methylation changes. Considering MEF enhancers ( Figure 4A ), we found that single CpGs in several clusters gained methylation toward the pluripotent state, as expected from averages measurements.","[2.0, 1.0, 2.0]",Medicine,train,1.6666666666666667,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1038/s41598-018-30980-y,Medicine_202,"Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report.",Greater nap slow wave activity was associated with greater memory decay during the nap.,"To do this, they presented children ages approximately three to five years (34-64 months) with faces paired with mean or nice word descriptions, but they saw no significant main effects of emotional valence on recognition memory. Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1111/gcb.13526,Medicine_203,"Alternatively, plants with fewer leaves are more water efficient, and thereby may be potentially drought tolerant.""","The additional savings in roots could then be used to further increase seed yield, making our predicted yield increase estimates conservative.","Cutting down on roots could produce additional carbon savings that the plant can invest towards boosting yield. Alternatively, plants with fewer leaves are more water efficient, and thereby may be potentially drought tolerant."" Next, the researchers will bioengineer plants or search for varieties that naturally have fewer leaves to test these preliminary findings on a larger scale.","S7) , plants with lower LAI can potentially have fewer roots and save on root investment and maintenance costs. The additional savings in roots could then be used to further increase seed yield, making our predicted yield increase estimates conservative. Alternatively maintaining the same amount of root, yet decreasing transpiration demand, would make the crop more drought tolerant which will assume increasing importance across the Midwest as predicted climate change develops .","[1.0, 3.0, 2.0]",Medicine,train,2.0,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1534/genetics.116.197285,Medicine_205,"We argue resistance could be thought of as a good thing -- if we know it's going to evolve, we can plan around it, and understand a gene drive is a temporary solution.","We have shown that for values of μ in this range, resistance is already likely when N e = 6 , which is compatible with estimates from levels of neutral diversity in insect populations 22 .","""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said. We argue resistance could be thought of as a good thing -- if we know it's going to evolve, we can plan around it, and understand a gene drive is a temporary solution. ""Obviously that doesn't work most of the time.","In addition, indels should occur within the 20 bp-long target sequence at rates comparable to the single nucleotide mutation rate 21 . We have shown that for values of μ in this range, resistance is already likely when N e = 6 , which is compatible with estimates from levels of neutral diversity in insect populations 22 . In many systems, the short-term values of N e relevant for a process as rapid as CGD may even be much larger than these values obtained from neutral diversity 17, 23 , which will often be dominated by seasonal population crashes (e.g., caused by the winters in a temperate region) and historical bottlenecks 24, 25 .","[4.0, 1.0, 1.0]",Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1126/scitranslmed.aab1290,Medicine_206,"DHED could be particularly useful in treating women who prematurely enter menopause after surgery, because they have the most drastic changes in hormone levels and often deal with symptoms for the longest, he points out.",We reveal the therapeutic potential of DHED on estrogen deficiency-associated neurological disorders and psychiatric conditions without encountering adverse systemic actions that are typically seen with the direct use of estrogens.,"""Because this prodrug remains completely inactive everywhere else in the body, you can remedy the neurological and psychiatric symptoms associated with estrogen deficiency while avoiding side effects in the rest of the body,"" Prokai says. DHED could be particularly useful in treating women who prematurely enter menopause after surgery, because they have the most drastic changes in hormone levels and often deal with symptoms for the longest, he points out. But although the drug holds promise for helping some women, such as those who have specific risk factors for cancer, Brinton says, it may not be an ideal first-line treatment for estrogen-deficiency in many others.","Although this method provides increased selectivity in CNS delivery of the hormone, it still generates elevated levels of the hormone in the periphery with substantial uterotrophic side effects and sustained high circulating estrogen levels even after acute dosing . We reveal the therapeutic potential of DHED on estrogen deficiency-associated neurological disorders and psychiatric conditions without encountering adverse systemic actions that are typically seen with the direct use of estrogens. The reductive bioactivation of DHED to E 2 proceeds through hydride transfer from the coenzyme NADPH to the C1 position of the C1-C2 double bond of DHED's Aring that is conjugated to the 3-carbonyl group.","[2.0, 3.0, 4.0, 2.0, 4.0]",Medicine,train,3.0,news,http://news.sciencemag.org/biology/2015/07/safer-estrogen-therapy-women
10.1002/hec.3070,Medicine_207,"While still imposing a relatively low tax burden, it could lead to weight reductions of up to 3.64 kilograms in middle-income heavy consumers of sweetened beverages.","Thus the per capita, per year, weight loss as a result of the tax is almost six times greater for heavy drinkers relative to persons drinking at an average level.","The effect would be even more striking if a 20 cents per litre volumetric tax were applied. While still imposing a relatively low tax burden, it could lead to weight reductions of up to 3.64 kilograms in middle-income heavy consumers of sweetened beverages. This was chiefly because although a sales tax would have a bigger effect on the price of single bottles, a volumetric tax meant those buying large quantities or discounted multipacks would face much steeper price increases.","Using this conversion criteria a reduction of 16,087 kJ as a result of the SSB tax translates into a reduction in body weight of 0.44 Kg (16,087/36,500 Kj) per year at mean level of consumption. Thus the per capita, per year, weight loss as a result of the tax is almost six times greater for heavy drinkers relative to persons drinking at an average level. This is a significant positive effect, considering that heavy drinkers would be a major target group for any tax policy.","[2.0, 3.0, 2.0, 3.0]",Medicine,train,2.5,news,http://www.sciencedaily.com/releases/2014/06/140617094037.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1039/c3cs60122f,Medicine_209,"Second, you must support researchers in their journey from paper to digital, as there are a lot of ELN software providers and not enough concrete information.","Forcing users to abandon paper notebooks and instead use an ELN is unlikely to be successful, users are much more likely to adopt an ELN if they can see some proven value that is relevant to their own work.","We should recognize that every lab has its own unique needs, and that there is no one-size-fits-all available today. Second, you must support researchers in their journey from paper to digital, as there are a lot of ELN software providers and not enough concrete information. Finally but most importantly, any ELN provider needs to provide an outstanding onboarding experience and continued support for researchers.","The authors of the information often do not share these same goals to the same extent, and the recording of their activities and data, and standardization of data entry, 4 is second to other aims such as performing the research activities and the interpretation of the data. Forcing users to abandon paper notebooks and instead use an ELN is unlikely to be successful, users are much more likely to adopt an ELN if they can see some proven value that is relevant to their own work. A paper notebook is not an effective tool from the point of view of the data manager or project supervisor, because it does not enable the access and sharing of data and information, it can only be read by one person at a time, it cannot be accessed anywhere, and it is difficult to search.","[3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=37060720905&p=1pl&v=1&x=mJkzlHa3lmu5bv8uh9G1ig
10.1016/j.cell.2018.04.034,Medicine_210,It was found to be more common in metastatic prostate cancer compared to early stage tumors that had not spread.,"Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy.","It was found to be more common in metastatic prostate cancer compared to early stage tumors that had not spread. Tumors in which CDK12 was inactivated were responsive to immune checkpoint inhibitors, a type of immunotherapy treatment that has overall had limited success in prostate cancer. ""Because prostate cancer is so common, 7 percent is a significant number.","We show that CDK12 mutants are genetically, transcriptionally, and phenotypically distinct from HRD and MMRD tumors. Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy. We detected aberrations of CDK12 in 25/360 of mCRPC patients (6.9%), 95% confidence interval (CI) [4.6%, 10 .2%] ( Figure 1A ).","[1.0, 1.0, 1.0, 3.0, 1.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=34322199988&p=1pl&v=1&x=uADO-y4eWDsh9N-tizLZ7Q
10.1152/ajpregu.00204.2013,Medicine_211,"And, since PE is a multifaceted disorder that begins with abnormal placental development before progressing to maternal disease, the results also suggest the possibility of preventing or treating early PE in humans with controlled CO dosages.",One of the goals of using CO as a possible future therapeutic in patients with PE would be to lower plasma sFLT1 levels.,"This study, the first to look at the effects of CO on the placenta in mice, found that exposing the animals to inhalable CO increased blood flow and vascular growth in the developing placenta, created more, bigger, and stronger connections to the mother's uterus, a process that provides more oxygen and nutrients to the fetus. And, since PE is a multifaceted disorder that begins with abnormal placental development before progressing to maternal disease, the results also suggest the possibility of preventing or treating early PE in humans with controlled CO dosages. Results Exposure to CO either continuously or in specific doses did not affect maternal weight (used as a measure of health) or litter size.","Therefore, it is possible that in our study, exposure to CO would not affect maternal plasma sFLT1 or VEGF levels until alterations in normal levels were first induced. One of the goals of using CO as a possible future therapeutic in patients with PE would be to lower plasma sFLT1 levels. In this regard, future studies would be necessary to investigate the effect of repeated exposure to short-term CO levels on maternal plasma sFLT1.","[3.0, 4.0, 4.0, 2.0]",Medicine,train,3.25,news,http://www.sciencedaily.com/releases/2013/09/130919154253.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1210/jc.2013-2350,Medicine_214,"""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening.""",We do not endorse the need for universal screening with androgen assays or ultrasound if patients already meet two of the three criteria clinically.,"""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening."" In the CPG, The Endocrine Society recommends that a diagnosis be made if adult women have two of the three cardinal features of PCOS (diagnostic criteria supported by the NIH panel): * Excess production of male hormones called androgens. Other recommendations from the CPG include:

* Because women with PCOS face an increased risk of pregnancy complications such as gestational diabetes, preterm delivery and preeclampsia that can be exacerbated by obesity, women should have their body mass index, blood pressure and oral glucose tolerance assessed prior to conceiving;

* Following diagnosis, women with PCOS should be examined for skin and hair complications including excess hair growth and acne;

* Although women with PCOS have some of the same risk factors associated with the development of endometrial cancer, they should not routinely undergo ultrasound screening for endometrial thickness;

* To gauge metabolic risk, adolescents and adult women with PCOS should be screened for increased obesity using body mass index and waist circumference measurements;

* Clinicians should give adolescents and adult women with PCOS an oral glucose tolerance test to check for type 2 diabetes or impaired glucose tolerance because they are at increased risk of these conditions; and

* Initial treatment of type 2 diabetes or impaired glucose tolerance in women with PCOS should be diet and exercise, with metformin as a second-line therapy.",These criteria allow the diagnosis to be made clinically (based upon a history of hyperandrogenic chronic anovulation) as well as biochemically with androgen assays or with ultrasound examination of the ovaries. We do not endorse the need for universal screening with androgen assays or ultrasound if patients already meet two of the three criteria clinically. It is recommended that the features leading to the diagnosis are documented.,"[4.0, 4.0, 5.0, 5.0, 5.0]",Medicine,train,4.6,news,http://www.sciencedaily.com/releases/2013/10/131024121206.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1002/hec.3070,Medicine_215,"""In absolute terms, the difference in tax over a year can be considered negligible, but the weight change could be significant, making these changes very cost effective,"" Sharma says.","This means that despite the lower tax burden, the reduction in consumption and body weight is higher under a volumetric tax.","Those who had been heavier consumers would lose more--between 1 and 2 kilos, or about 2 to 4.5 pounds. ""In absolute terms, the difference in tax over a year can be considered negligible, but the weight change could be significant, making these changes very cost effective,"" Sharma says. The effect would be even more striking if a 20 cents per liter volumetric tax were applied.","The tax burden under a 20% valoric tax and a 20 cents/litre volumetric tax is around $17 and $11 per capita per year, respectively. This means that despite the lower tax burden, the reduction in consumption and body weight is higher under a volumetric tax. This is an interesting result, even more interesting for high level consumers who lose even more weight for small marginal absolute dollar outlays, meaning interventions are very costeffective as we discuss in more detail in due course.","[4.0, 3.0, 4.0]",Medicine,train,3.6666666666666665,news,http://www.theepochtimes.com/n3/778129-higher-soda-tax-may-help-consumers-tighten-their-belt/
10.1016/j.celrep.2016.08.013,Medicine_216,"By calculating the displacement of bacteria from the endothelial cells, the researchers also found that the microbes use bungee-cord-like tethers to stabilize and strengthen these bonds.",This finding suggested that motility is possibly strong enough to modulate the force imposed on load-bearing bonds and drive active bacterial migration over endothelia under PCV shear stress.,"""Our in vitro live-cell-imaging-based system will permit more efficient dissection of the underlying interaction mechanisms and more rapid screening for inhibitors of bacterial-endothelial interactions and dissemination."" By calculating the displacement of bacteria from the endothelial cells, the researchers also found that the microbes use bungee-cord-like tethers to stabilize and strengthen these bonds. Similar to children swinging on monkey bars, the bacteria transferred force from one bond to the next without fully detaching, slowing down every time they established a new bond and accelerating when they broke a bond and transitioned to the next one.","Thus, unexpectedly, B. burgdorferi experienced forces that were small enough to be overcome by bacterial motility. This finding suggested that motility is possibly strong enough to modulate the force imposed on load-bearing bonds and drive active bacterial migration over endothelia under PCV shear stress. We also found that average bond forces for BBK32-producing GCB966 were larger than for bbk32-deficient GCB971 ( Figure 4B ), that most GCB966 interactions occurred at higher bond forces than GCB971 ( Figure 4C ), and that GCB966 interactions occurred at a higher average shear stress and shear stress range than GCB971 interactions ( Figures 4D and 4E ).","[4.0, 4.0, 2.0, 4.0]",Medicine,train,3.5,news,https://www.sciencedaily.com/releases/2016/08/160825130027.htm
10.1007/s00125-014-3400-z,Medicine_217,"Our results suggest that preventive strategies, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.""","The incidence rate of type 1 diabetes was lower in the non-EV than the EV group (4 vs 6 per 100,000 person-years; incidence rate ratio 1.48 [95% CI 1.19, 1.83]) ( Table 2 ).","They add: ""Taiwan has relatively low type 1 diabetes incidence; we believe that the marked escalation of the said incidence in recent decades can be largely attributed to the highly endemic spread of enterovirus infection in Taiwanese children, given that there has been little gene flow and genetic drift in such a short period."" They conclude: ""This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection. Our results suggest that preventive strategies, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.""","Compared with the non-EV group, the EV group had a significantly higher prevalence of atopic dermatitis, allergic rhinitis and bronchial asthma ( Table 1) . The incidence rate of type 1 diabetes was lower in the non-EV than the EV group (4 vs 6 per 100,000 person-years; incidence rate ratio 1.48 [95% CI 1.19, 1.83]) ( Table 2 ). The incidence rate proved consistently lower for the non-EV than the EV group, except for children aged 10 years and over, as well as those with allergic rhinitis or bronchial asthma.","[4.0, 3.0, 5.0, 4.0]",Medicine,train,4.0,news,http://www.sciencedaily.com/releases/2014/10/141017183715.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1210/jc.2013-2350,Medicine_218,"Women who had PCOS were more likely to have miscarriages, ectopic pregnancies or other gynecological conditions such as irregular menstrual periods and endometriosis.",We recognize that the diagnosis of PCOS in postmenopausal women is problematic but feel that it is unlikely that a woman can develop PCOS in the perimenopause or menopause if she has not had symptoms earlier.,"Researchers analyzing the data found women who were diagnosed with PCOS were more likely to be hospitalized for reasons unrelated to reproductive health or injury than their counterparts. Women who had PCOS were more likely to have miscarriages, ectopic pregnancies or other gynecological conditions such as irregular menstrual periods and endometriosis. Women who had PCOS also had a higher rate of endometrial cancer, or cancer of the lining of the uterus.","Very high T levels and/or virilization may suggest an androgen-producing tumor in postmenopausal women. We recognize that the diagnosis of PCOS in postmenopausal women is problematic but feel that it is unlikely that a woman can develop PCOS in the perimenopause or menopause if she has not had symptoms earlier. 2.1 We recommend that a physical examination should document cutaneous manifestations of PCOS: terminal hair growth (see hirsutism guidelines, Ref.","[3.0, 2.0, 3.0]",Medicine,train,2.6666666666666665,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1038/s41598-018-25573-8,Medicine_219,The biodegradable PMO carrying doxorubicin quickly eliminated the human ovarian tumours without affecting other organs in the chicken embryo.,The above results show that the nanoparticle formulation enables a higher amount of doxorubicin to be administered safely.,"This is a major step toward individualized medicine for cancer patients. The biodegradable PMO carrying doxorubicin quickly eliminated the human ovarian tumours without affecting other organs in the chicken embryo. When a smaller amount of the drug, not enveloped in the nanoparticles, was injected in the egg, severe organ damage ensued.",Doxorubicin is specifically delivered to the tumor after intravenous administration of doxorubicin loaded MSNs. The above results show that the nanoparticle formulation enables a higher amount of doxorubicin to be administered safely. As can be seen in Fig.,"[2.0, 2.0, 2.0, 4.0, 3.0]",Medicine,train,2.6,news,http://ct.moreover.com/?a=34220579892&p=1pl&v=1&x=hyv7yBfI9spqaAdmPr3ViA
10.1001/jamapediatrics.2018.0302,Medicine_22,"""Moreover, we found that the lower dose of vitamin D supplementation (up to 2,000 IU a day) reduced risk of fetal or neonatal mortality and infants being small for gestational age, but higher doses (more than 2,000 IU a day) did not reduce the risk of perinatal mortality and infants being small for gestational age,"" Wei said by email.","Late vitamin D supplementation (initiation at ≥20 weeks' gestation) improved birth weight, but early supplementation (initiation at <20 weeks' gestation) did not.","And supplementation reduced infants' risk of being small for gestational age and improved their calcium levels and growth in the first 12 months of life. ""Moreover, we found that the lower dose of vitamin D supplementation (up to 2,000 IU a day) reduced risk of fetal or neonatal mortality and infants being small for gestational age, but higher doses (more than 2,000 IU a day) did not reduce the risk of perinatal mortality and infants being small for gestational age,"" Wei said by email. They didn't find a meaningful difference in birth defects based on whether mothers took vitamin D during pregnancy.","We found that maternal vitamin D supplementation timing, dose, and administration method did not affect cord blood vitamin D concentration. Late vitamin D supplementation (initiation at ≥20 weeks' gestation) improved birth weight, but early supplementation (initiation at <20 weeks' gestation) did not. Most importantly, we found that the lower dose of vitamin D supplementation (≤2000 IU/d) reduced the risk of fetal or neonatal mortality and SGA, but the higher dose (>2000 IU/d) did not.","[1.0, 1.0, 5.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=34180824606&p=1pl&v=1&x=LymT53igqmp5seujNS7GFA
10.1016/j.ijnurstu.2014.02.007,Medicine_220,"Recent catastrophic failures such as events at Mid-Staffordshire have highlighted the importance of staffing levels to patient survival, and this study has reinforced that message.""","In the third column, however, we can see that the equivalent interaction is not significant when it involves the number of consultants.","Professor Elizabeth West, pictured, who led the research, says: ""This is timely because the public are concerned about the ability of the NHS to provide safe and compassionate care. Recent catastrophic failures such as events at Mid-Staffordshire have highlighted the importance of staffing levels to patient survival, and this study has reinforced that message."" This is the first study of patient survival in ICUs to look at the numbers of doctors as well as nurses.","Column two shows that the interaction variable is negative and significant, implying that the reduction in mortality risk from having more nurses is larger for patients who are the most severely ill. In the third column, however, we can see that the equivalent interaction is not significant when it involves the number of consultants. By way of example, we can calculate that the effect of increasing the number of nurses per bed from four to six is to reduce the probability of mortality for patients with a predicted log odds of mortality of -3 from .017 to .016.","[1.0, 1.0, 2.0, 1.0]",Medicine,train,1.25,news,http://www.healthcanal.com/public-health-safety/49249-low-icu-staffing-levels-affect-patient-survival.html
10.1001/jamapediatrics.2018.0302,Medicine_221,This amount of vitamin D was tied to 55 percent lower odds of an underweight baby and 65 lower chance of a baby dying in the womb or during infancy.,"Vitamin D supplementation was associated with higher neonatal vitamin D status (bolus-or regular-dose supplement and early or late timing were equally effective in attaining improvement in vitamin D levels), higher calcium levels, higher Apgar scores, greater neonatal skinfold thickness, greater weight (at birth, 3 months, 6 months, 9 months, and 12 months), and greater height (at 3 months, 9 months, and 12 months) in the offspring.","But prenatal vitamin D supplements only appeared to have these benefits when women took 2,000 International Units (IU) or less each day. This amount of vitamin D was tied to 55 percent lower odds of an underweight baby and 65 lower chance of a baby dying in the womb or during infancy. At higher doses, any differences between women who took vitamin D and those who didn't were too small to rule out the possibility that they were due to chance.","Vitamin D supplementation during pregnancy with lower doses (≤2000 IU/d) was associated with a reduced risk of fetal and neonatal mortality. Vitamin D supplementation was associated with higher neonatal vitamin D status (bolus-or regular-dose supplement and early or late timing were equally effective in attaining improvement in vitamin D levels), higher calcium levels, higher Apgar scores, greater neonatal skinfold thickness, greater weight (at birth, 3 months, 6 months, 9 months, and 12 months), and greater height (at 3 months, 9 months, and 12 months) in the offspring. Timing of vitamin D supplementation affected birth weight.","[3.0, 3.0, 4.0]",Medicine,train,3.333333333333333,news,http://ct.moreover.com/?a=34180824606&p=1pl&v=1&x=LymT53igqmp5seujNS7GFA
10.1038/s41467-019-09863-x,Medicine_225,"Still, in the meantime, there are other kinds of ""tipping points"" that may be of much more immediate concern, according to climate scientist Robert Kopp of Rutgers University, who commented on the new study for E&E News.","Our results show that the PCF gets progressively stronger in warmer climates, while the SAF weakens.","On that kind of time scale, their impact could be formidable. Still, in the meantime, there are other kinds of ""tipping points"" that may be of much more immediate concern, according to climate scientist Robert Kopp of Rutgers University, who commented on the new study for E&E News. Kopp pointed to the risk of socio-economic tipping points--changes in a society's ability to respond to or recover from repeated exposure to increasingly extreme weather or other severe climate-related events, such as hurricanes, wildfires or floods.","While not modelled directly, many of these effects are included implicitly in the PAGE-ICE IAM through a number of uncertain climate system parameters constrained according to the latest literature (Methods, Supplementary Note 1). Our results show that the PCF gets progressively stronger in warmer climates, while the SAF weakens. The PCF also develops state-dependent lagged behaviour.","[1.0, 1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1098/rspb.2013.3172,Medicine_226,Our research suggests that health officials need to have a really good understanding of the social context to better understand vaccine scares and why people refuse vaccines.,"Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels.","""They are strongly influenced by other parents and what they read. Our research suggests that health officials need to have a really good understanding of the social context to better understand vaccine scares and why people refuse vaccines. Bauch believes this may steadily lead to less immunized children, where populations may become vulnerable to such diseases.","The social learning rate k can also influence whether the population converges to no vaccine coverage or returns to full vaccine coverage, after a vaccine scare (figure 5). Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels. This is obvious in comparisons of the fitted model appearing in figure 1e,f to simulations of the same model, but where the pertussis vaccine scare never occurred (s ¼ 1, figure 6 ).","[4.0, 3.0, 2.0, 3.0]",Medicine,train,3.0,news,http://www.medicaldaily.com/spread-infectious-diseases-influenced-vaccine-scares-and-public-paranoia-269370
10.1073/pnas.1318978111,Medicine_229,"Authors believe the study provides potential biological targets to enhance fertility in women with diminished ovarian reserve, who produce few or no follicles in response to IVF drugs designed to boost follicle development.","S2D ), suggesting that androgens promote FSHR protein expression independent of transcription.","Authors believe the study provides potential biological targets to enhance fertility in women with diminished ovarian reserve, who produce few or no follicles in response to IVF drugs designed to boost follicle development. ""Our study doesn't solve the controversy, but, along with some earlier seminal studies from other groups, it does tell us that we can't dismiss male hormones. They might actually be doing something useful.""","5A ) nor testosterone (Fig S2D) alters FSHR mRNA levels, but both significantly increase FSHR protein expression (Fig. S2D ), suggesting that androgens promote FSHR protein expression independent of transcription. S3A ), indicating that DHT promotes FSHR protein expression by enhancing translation through extranuclear AR signaling.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0324-7,Medicine_230,"These are some of the reasons to think this isn't random (and that this non-randomness is bad news for women):

""First, if men and women expect families to prioritize husbands' careers in relocation decisions, this may in turn compel women to sort into flexible occupations, thereby reproducing occupational segregation...""

""Second, the segregation of women into flexible occupations may be a byproduct of other occupational characteristics.","In other words, the tendency for families to relocate for men's careers may be a feature of men's and women's ex ante career choices rather than families' ex post prioritization of husband's careers, and therefore endogenous.","Note that the occupations on the left-hand side are, on the whole, much higher paid than the ones on the right. These are some of the reasons to think this isn't random (and that this non-randomness is bad news for women):

""First, if men and women expect families to prioritize husbands' careers in relocation decisions, this may in turn compel women to sort into flexible occupations, thereby reproducing occupational segregation...""

""Second, the segregation of women into flexible occupations may be a byproduct of other occupational characteristics. There are a lot of things this could mean.","However, occupations are not random by sex, and mobility is not random by occupation; this assumption is violated if men and women segregate into geographically constrained and flexible occupations, as would be the case if their career choices are made in anticipation of the two-body problem or if labor market processes otherwise channel women into jobs that can be performed anywhere. In other words, the tendency for families to relocate for men's careers may be a feature of men's and women's ex ante career choices rather than families' ex post prioritization of husband's careers, and therefore endogenous. Among never-married workers, I find that men are more likely than women to relocate for work.","[3.0, 4.0, 2.0, 2.0]",Medicine,train,2.75,news,http://www.businessinsider.com/why-women-choose-more-flexible-careers-2014-11
10.1146/annurev-publhealth-031914-122421,Medicine_231,"Their analysis, published in the March issue of the Annual Review of Public Health, identifies four problem areas related to health care delivery to Latinos under ACA:

The consequences of not covering undocumented residents.",Research into health care disparities affecting Latinos will likely change rapidly during the next two decades because of two important policy and sociodemographic changes.,"Latinos' low rates of insurance coverage and poor access to health care strongly suggest a need for better outreach by health care providers and an improvement in insurance coverage. Their analysis, published in the March issue of the Annual Review of Public Health, identifies four problem areas related to health care delivery to Latinos under ACA:

The consequences of not covering undocumented residents. The heavier demand on public and private health care systems serving newly insured Latinos.","Care 535 patient, provider, and system factors that explains such disparities . Research into health care disparities affecting Latinos will likely change rapidly during the next two decades because of two important policy and sociodemographic changes. First, the implementation of the ACA will provide new topics of inquiry, such as the identification of new areas of disparities in health care including those between eligible and ineligible Latino populations (e.g., documented versus undocumented immigrants) as well as those within eligible populations.","[4.0, 1.0, 2.0, 4.0, 2.0]",Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150319092222.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29
10.1038/s41598-018-29793-w,Medicine_232,"""It's not going to be so simple, I don't think, as saying, 'OK, what happens if you give a probiotic?'""","We demonstrated that the baseline nasal microbiota clusters were associated with subsequent nasal inflammatory response, viral titer, and symptom severity in rhinovirus infection.","So it's not like the probiotic alters the microbiome of the gut in any substantial way."" It's possible that administering a probiotic directly to the nose, such as through a spray, could have more effect. ""It's not going to be so simple, I don't think, as saying, 'OK, what happens if you give a probiotic?'""","Whether intranasal administration of probiotic to the human host would amplify the effects seen following oral administration remains to be determined. We demonstrated that the baseline nasal microbiota clusters were associated with subsequent nasal inflammatory response, viral titer, and symptom severity in rhinovirus infection. Given the exploratory nature of our study, further investigations are needed to confirm the relationship between the nasal microbiota, host response and","[3.0, 2.0, 2.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=37225510845&p=1pl&v=1&x=cC_QQTJtCDR1qED9-8SGHg
10.1038/s41589-018-0155-8,Medicine_234,"However, in further experiments conducted by the laboratory of study co-senior author John Teijaro, an assistant professor in the Department of Immunology and Microbiology at Scripps Research, it was clear that the reduction in ABHD12 activity had a big effect on the mouse immune system.","Taken together, these data indicate that the inactivation of ABHD12 promotes increased lung ) , regulated on activation, normal T cell expressed and secreted.","The rise wasn't as great as that seen in the ABHD12-knockout mice, and even four weeks of treatment with the inhibitor appeared to cause only slight hearing defects -- nothing like the profound defects experienced by PHARC patients. However, in further experiments conducted by the laboratory of study co-senior author John Teijaro, an assistant professor in the Department of Immunology and Microbiology at Scripps Research, it was clear that the reduction in ABHD12 activity had a big effect on the mouse immune system. Ordinary mice infected with LCMV clone 13 typically have minor symptoms but take a long time to clear the infection.","Finally, ABHD12 -/mice that survived the initial exaggerated immune response (~days 8-15) displayed a gradual reduction in viral titers in the serum and lung over the ensuing weeks (Fig. Taken together, these data indicate that the inactivation of ABHD12 promotes increased lung ) , regulated on activation, normal T cell expressed and secreted. e, ABHD12 -/mice kill adoptively transferred splenocytes displaying LCMV-specific antigen (GP33-41) more efficiently than ABHD12 +/+ mice.","[4.0, 2.0, 3.0, 4.0, 5.0]",Medicine,train,3.6,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/s41598-018-26198-7,Medicine_236,Their analyses further suggested that stretching may impact on two possibly related mechanisms that are relevant to cancer--immune cell exhaustion and inflammation resolution.,"We next examined tumor cytokine levels and found that, even though individual group differences were not statistically significant, overall levels of inflammatory mediators, including IL-2, IL-6, IL-10, TNF-α and INF-γ, were up-regulated in the stretch group (Table 1) .","Their analyses further suggested that stretching may impact on two possibly related mechanisms that are relevant to cancer--immune cell exhaustion and inflammation resolution. Writing in their published paper in Scientific Reports, the researchers conclude, ""The potential clinical significance of our results lies in the possibility of developing a method of gentle stretching that could be well tolerated and testable in humans for primary or secondary cancer prevention, or in conjunction with cancer treatment."" Mice can quickly become accustomed to holding this position for 10 minutes at a time, without evidence of discomfort.","We found no significant difference in the abundance of macrophages expressing CD64 (M1) and CD206/Arg (M2) between stretch and no-stretch groups ( Table 1 ). We next examined tumor cytokine levels and found that, even though individual group differences were not statistically significant, overall levels of inflammatory mediators, including IL-2, IL-6, IL-10, TNF-α and INF-γ, were up-regulated in the stretch group (Table 1) . Gene set enrichment analysis (GSEA) revealed multiple gene signatures related to the immune response, including IFN-α, INF-γ, inflammatory response and allograft rejection, as the top enriched gene sets in the stretch group ( Fig.","[4.0, 3.0, 3.0, 2.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=34125675804&p=1pl&v=1&x=EIuTbzUDbEKkr7kvXb-kdg
10.1001/jamapsychiatry.2015.0500,Medicine_238,"Psychotherapy has made progress but is still being utilized by only a small portion of young people being treated with antipsychotics, according to the study.","Less than one-fourth of the patients in each of the age groups had an outpatient claim for psychotherapy (younger children, 13.5%; older children, 20.4%; adolescents, 24.8%; young adults, 18.8%) ( Table 4) .","""We may need to put greater effort into increasing access to psychosocial interventions that can treat symptoms and behaviors that are currently being addressed with antipsychotic medications."" Psychotherapy has made progress but is still being utilized by only a small portion of young people being treated with antipsychotics, according to the study. Olfson pointed out that more research is needed to determine the factors that are currently impeding access to psychotherapy for children and teens in need of it.","Among antipsychotic-treated children and adolescents with mental disorder claims, the most common diagnosis was ADHD (younger children, 52.5%; older children, 60.1%; adolescents, 34.9%), while depression was the most common diagnosis among young adults (34.5%), followed by bipolar (26.6%) and anxiety disorders (22.9%). Less than one-fourth of the patients in each of the age groups had an outpatient claim for psychotherapy (younger children, 13.5%; older children, 20.4%; adolescents, 24.8%; young adults, 18.8%) ( Table 4) . In contrast with earlier reports 7-9 of increasing antipsychotic treatment of US children through the early 2000s, the percentage of children treated with antipsychotics was lower in 2010 than in 2006.","[5.0, 2.0, 3.0, 2.0]",Medicine,train,4.0,news,http://www.medicaldaily.com/prescription-drug-use-retrospective-study-shows-decreased-antipsychotic-drug-340770
10.1001/jamasurg.2018.0672,Medicine_24,"""Our results suggest that functional health literacy can now also be included as an influencing factor for the quality of postoperative recovery,"" wrote the authors, who added that FHL should be considered a relevant factor in considering how to best optimize recovery for patients undergoing day surgery.In a linked commentary Jesse P Wright, MD; Kelvin Moses, MD, PhD; and Kamran Idrees, MD, MSCI, MMHC, wrote that ""we question if patients are able to equally discern the difference in the questioning in the quality of recovery and [quality of life] questionnaires"" used in the study, but said that ""The findings in this ambulatory setting mirror findings by our group where we reported an association of low health literacy with various postoperative metrics, including increased hospital length of stay and use of discharge resources in patients undergoing surgical procedures.",Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery.,"Those with inadequate FHL had the following when compared with those with sufficient FHL:Health-related quality of life, as measured by the EuroQol-visual analog scale, also revealed poorer outcomes for those with inadequate FHL; this group had worse scores for physical function, vitality, social functioning, and mental health. ""Our results suggest that functional health literacy can now also be included as an influencing factor for the quality of postoperative recovery,"" wrote the authors, who added that FHL should be considered a relevant factor in considering how to best optimize recovery for patients undergoing day surgery.In a linked commentary Jesse P Wright, MD; Kelvin Moses, MD, PhD; and Kamran Idrees, MD, MSCI, MMHC, wrote that ""we question if patients are able to equally discern the difference in the questioning in the quality of recovery and [quality of life] questionnaires"" used in the study, but said that ""The findings in this ambulatory setting mirror findings by our group where we reported an association of low health literacy with various postoperative metrics, including increased hospital length of stay and use of discharge resources in patients undergoing surgical procedures. ""The commentary's authors say that investment in development of validated tools to measure FHL will generate the empirical data necessary to develop and use appropriate health literacy interventions.1.","CONCLUSIONS AND RELEVANCE Inadequate FHL in patients undergoing day surgery was associated with poorer postoperative recovery and a lower health-related quality of life. Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery. 6 Considering this, the association between FHL and postoperative recovery in patients undergoing day surgery needs to be assessed.","[5.0, 4.0, 5.0, 5.0]",Medicine,train,4.75,news,http://ct.moreover.com/?a=33887433087&p=1pl&v=1&x=9eFFYNmEjRb2HVG-5W6y0Q
10.1210/jc.2013-2350,Medicine_240,"Other recommendations from the CPG include:

* Because women with PCOS face an increased risk of pregnancy complications such as gestational diabetes, preterm delivery and preeclampsia that can be exacerbated by obesity, women should have their body mass index, blood pressure and oral glucose tolerance assessed prior to conceiving;

* Following diagnosis, women with PCOS should be examined for skin and hair complications including excess hair growth and acne;

* Although women with PCOS have some of the same risk factors associated with the development of endometrial cancer, they should not routinely undergo ultrasound screening for endometrial thickness;

* To gauge metabolic risk, adolescents and adult women with PCOS should be screened for increased obesity using body mass index and waist circumference measurements;

* Clinicians should give adolescents and adult women with PCOS an oral glucose tolerance test to check for type 2 diabetes or impaired glucose tolerance because they are at increased risk of these conditions; and

* Initial treatment of type 2 diabetes or impaired glucose tolerance in women with PCOS should be diet and exercise, with metformin as a second-line therapy.","In addition, the nocturnal drop in mean arterial blood pressure is lower, a finding that has also been demonstrated in obese adolescents with PCOS .","""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening."" In the CPG, The Endocrine Society recommends that a diagnosis be made if adult women have two of the three cardinal features of PCOS (diagnostic criteria supported by the NIH panel): * Excess production of male hormones called androgens. Other recommendations from the CPG include:

* Because women with PCOS face an increased risk of pregnancy complications such as gestational diabetes, preterm delivery and preeclampsia that can be exacerbated by obesity, women should have their body mass index, blood pressure and oral glucose tolerance assessed prior to conceiving;

* Following diagnosis, women with PCOS should be examined for skin and hair complications including excess hair growth and acne;

* Although women with PCOS have some of the same risk factors associated with the development of endometrial cancer, they should not routinely undergo ultrasound screening for endometrial thickness;

* To gauge metabolic risk, adolescents and adult women with PCOS should be screened for increased obesity using body mass index and waist circumference measurements;

* Clinicians should give adolescents and adult women with PCOS an oral glucose tolerance test to check for type 2 diabetes or impaired glucose tolerance because they are at increased risk of these conditions; and

* Initial treatment of type 2 diabetes or impaired glucose tolerance in women with PCOS should be diet and exercise, with metformin as a second-line therapy.","Women with PCOS should have BMI and blood pressure measured at each clinic visit (and consider waist circumference if nonobese; Ն 36 inches is abnormal), and upon diagnosis of PCOS, additional testing should include a complete fasting lipid profile (total cholesterol, LDL-cholesterol, non-HDL-cholesterol, HDL-cholesterol, and triglycerides). In addition, the nocturnal drop in mean arterial blood pressure is lower, a finding that has also been demonstrated in obese adolescents with PCOS . Another marker of atherosclerosis, coronary artery calcification, is more common in women with PCOS than in controls, even after adjusting for the effects of age and BMI .","[4.0, 4.0, 2.0, 5.0]",Medicine,train,3.75,news,http://www.sciencedaily.com/releases/2013/10/131024121206.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.molcel.2014.05.030,Medicine_241,D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study.,"In any case, our findings suggest that PKA-mediated phosphorylation of ATR at Ser435 is an important event that dynamically regulates early recruitment/assembly of XPA and possibly other DNA repair proteins to sites of UV damage to optimize NER.","""If you tend to burn, then you may have inherited a problem with your MC1R, and you probably should avoid purposeful UV exposure like tanning bed use or unprotected sun exposure."" D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study. The team hopes to use this information to develop new melanoma-preventive treatments, like additives that can be included in sunblocks to ramp up the skin's ability to deal with UV damage.","It is possible that the phospho-Ser435 ATR-XPA complex recognizes UV damaged sites through RPA binding (Zou and Elledge, 2003) or perhaps via the excision gap generated by NER . In any case, our findings suggest that PKA-mediated phosphorylation of ATR at Ser435 is an important event that dynamically regulates early recruitment/assembly of XPA and possibly other DNA repair proteins to sites of UV damage to optimize NER. Equal loading of PKA and substrate peptides was 17 confirmed by SYPRO Ruby staining (Invitrogen).","[3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2015.0500,Medicine_242,"""Antipsychotics should be prescribed with care,"" says Michael Schoenbaum, co-author of the study and senior adviser for mental health services, epidemiology and economics at the National Institute of Mental Health.","Young adults treated with antipsychotics were more frequently diagnosed as having depression, bipolar disorder, and anxiety disorder than ADHD.","""Antipsychotics should be prescribed with care,"" says Michael Schoenbaum, co-author of the study and senior adviser for mental health services, epidemiology and economics at the National Institute of Mental Health. Even after medication has stopped, these effects may still persist. The percentage dropped to about half a percent by the time they reach the age of 19.","Consistent with clinical diagnoses suggesting that antipsychotics are primarily used to manage impulsive or aggressive behaviors in children associated with ADHD, 27 the highest rate of antipsychotic treatment was in adolescent boys, approximately half of whom also filled prescriptions for stimulants. Young adults treated with antipsychotics were more frequently diagnosed as having depression, bipolar disorder, and anxiety disorder than ADHD. The single year of age and sex patterns of antipsychotic use offers clues to clinical and social determinants of community antipsychotic prescribing practices.","[2.0, 4.0, 4.0, 3.0]",Medicine,train,3.25,news,http://www.techtimes.com/articles/65576/20150702/boys-with-adhd-more-likely-to-be-given-antipsychotics-study.htm
10.1038/s41467-019-08382-z,Medicine_243,These interactions help Hel2 identify flaws in protein formation.,"The major Hel2 crosslink site (C1490-A1492 in yeast; C1554-A1556 in human) and the minor crosslink site of the 3' domain (U1362 in yeast; U1426 in human) both lie close to the 40S-40S interface, indicating that Hel2 and Asc1 may be even closer than judged from the monosome structure.","This clears the way for further proteins to be produced. These interactions help Hel2 identify flaws in protein formation. When researchers removed the parts of Hel2 in direct contact, this prevented the destruction of faulty proteins, showing that these contacts are important for the mechanism.","In collided diribosomes, the interface between both 40S subunits contains hRACK1 of the first (stalled) ribosome and hRPS10, hRPS20 and hRPS3 of the following (collided) ribosome 45 and hRPS10 ubiquitination by hZNF598 happens in the context of the collided ribosomes 45 . The major Hel2 crosslink site (C1490-A1492 in yeast; C1554-A1556 in human) and the minor crosslink site of the 3' domain (U1362 in yeast; U1426 in human) both lie close to the 40S-40S interface, indicating that Hel2 and Asc1 may be even closer than judged from the monosome structure. However, the second minor crosslink site (U494 in yeast; U542 in human) would be buried between the collided ribosomes.","[4.0, 2.0, 2.0, 3.0, 3.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=38442592628&p=1pl&v=1&x=6qnjJlZN_F0RgmqDHnl0dA
10.1007/s13524-014-0321-x,Medicine_245,"Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses.""","Older parents may be more ""ready"" for parenthood or may have been anticipating it more intently .","Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources. Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses."" Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child.","Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short-and long-term responses to a birth. Older parents may be more ""ready"" for parenthood or may have been anticipating it more intently . If people see young parents with few resources having a difficult time and others with many resources having an easier time, this may send a message to postpone childbearing.","[1.0, 1.0, 2.0, 3.0]",Medicine,train,1.75,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1702671114,Medicine_246,Scientists had believed the Lombard effect was much slower: about 150 milliseconds for birds and bats and approximately150 to 175 milliseconds for humans.,"Here, to the contrary, we show that the Lombard effect is a direct response to background noise and features an extremely short latency of about 30 ms.","When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization. Even in terms of near-instantaneous brain reactions, they call this reflex ""remarkably short."" Scientists had believed the Lombard effect was much slower: about 150 milliseconds for birds and bats and approximately150 to 175 milliseconds for humans.","Because background noise interferes with the feedback amplitude of an animal's vocalizations, the magnitude of the Lombard effect grows stronger with increasing background noise. Here, to the contrary, we show that the Lombard effect is a direct response to background noise and features an extremely short latency of about 30 ms. Thus, the Lombard effect can be better described as a reflex.","[2.0, 2.0, 5.0, 3.0, 4.0]",Medicine,train,3.2,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1038/s41586-018-0731-9,Medicine_247,"But they can analyze optical light from this region, and the details they've found have let them confirm the mass of the central black hole at about 300 million solar masses.","The angular size of each component scales with the observed optical flux 6 , making interferometry particularly well suited to exploring the physical origin of the broad-line region and to measuring black-hole masses in luminous quasars such as 3C 273, which are more representative of the supermassive black holes found in large samples out to high redshift.","Then, in the video, you see what's new here: a depiction of a spinning whirlpool, an artist's concept of the recent work completed by astronomers, who were able to get some details about the so-called broad line region, where gas clouds whirl around 3C 273's central black hole. But they can analyze optical light from this region, and the details they've found have let them confirm the mass of the central black hole at about 300 million solar masses. That's in contrast to the mass of the supermassive black hole at the center of our own Milky Way galaxy, which is only about 4 million solar masses.","Future observations could aim to measure a rotation curve and search for additional (for example, outflow) components and structural variability. The angular size of each component scales with the observed optical flux 6 , making interferometry particularly well suited to exploring the physical origin of the broad-line region and to measuring black-hole masses in luminous quasars such as 3C 273, which are more representative of the supermassive black holes found in large samples out to high redshift. These authors contributed equally: E. Sturm, J. Dexter.","[4.0, 1.0, 3.0, 1.0, 2.0]",Medicine,train,2.2,news,https://earthsky.org/space/1st-close-up-look-supermassive-black-hole-3c273
10.1038/s41598-017-03627-7,Medicine_248,"In the third condition, because of the partner's touch, the women experienced less pain.","In line with our hypotheses, the coupling during touch increased compared to during no touch in both the no pain (Δζ t/nt(np) = 0.010, p < 0.001, 95% CI [0.006, 0.014]) and the pain (Δζ t/nt(p) = 0.008, p < 0.001, 95% CI [0.003, 0.012]) conditions.","That's almost as many as the entire population of Texas. In the third condition, because of the partner's touch, the women experienced less pain. It seems that hyperscanning, or this brain-to-brain coupling by the act of hand-holding while in pain, may have a soothing, analgesic effect, like the skin-to-skin touch that is beneficial to premature babies.","No significant cross-partner effects were detected for the pain alone (ζ a(p) = −0.001, p = 0.64) or the no pain alone (ζ a(np) < 0.001, p = 0.92) conditions. In line with our hypotheses, the coupling during touch increased compared to during no touch in both the no pain (Δζ t/nt(np) = 0.010, p < 0.001, 95% CI [0.006, 0.014]) and the pain (Δζ t/nt(p) = 0.008, p < 0.001, 95% CI [0.003, 0.012]) conditions. However, there was no difference between pain and no pain during both touch (Δζ t(p/np) = 0.004, p = 0.115) and no touch (Δζ nt(p/np) = 0.002, p = 0.637) conditions.","[1.0, 3.0, 3.0, 2.0, 3.0]",Medicine,train,2.4,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1073/pnas.1706244114,Medicine_249,"""Our findings suggest that ammonia hemihydrate could be an important component of the mantle in ice giants, and will help improve our understanding of these frozen worlds.""",We suggest that ammonia-rich hydrates can precipitate out of any ammonia-water mixture at sufficient pressures and are an important component inside icy planets.,"The findings will influence how ice giants are studied in future and could help astronomers classify newly discovered exoplanets as they look deeper into space. ""This study helps us better predict what is inside icy planets like Neptune,"" Dr. Hermann said. ""Our findings suggest that ammonia hemihydrate could be an important component of the mantle in ice giants, and will help improve our understanding of these frozen worlds.""","The energetic cost of breaking the N-H bond is outweighed by ionic bonding NH + 4 · · · NH − 2 and more compact packing. We suggest that ammonia-rich hydrates can precipitate out of any ammonia-water mixture at sufficient pressures and are an important component inside icy planets. However, it is a crucial phase at high pressure and temperature, where both ADH and AMH decompose into AHH + ice-VII, around 3 GPa and at 280 K and 250 K, respectively .","[4.0, 3.0, 4.0, 2.0, 2.0]",Medicine,train,3.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/pxZKfMqr6dA/chemical-make-up-ice-giants-05122.html
10.1186/s13293-018-0204-8,Medicine_25,"The authors note that the review paper should serve as an overview of the current knowledge regarding sex differences in the lower urinary tract, as well as a catalyst for investigators seeking to contribute to the field.","This review serves to characterize the current understanding of biological sex differences between female and male lower urinary tracts, while identifying areas for future research.","""These differences need to be taken into account when treating urinary dysfunction in order to provide optimal treatment for both women and men."" The authors note that the review paper should serve as an overview of the current knowledge regarding sex differences in the lower urinary tract, as well as a catalyst for investigators seeking to contribute to the field. Further investigation of sex differences in lower urinary tract cell types is necessary to better develop our understanding of normal and abnormal function, and specifically, the paper states that more research is needed regarding:","Recognizing that cell biology is not uniform, especially in the lower urinary tract of females and males, is crucial for providing context and relevance for diverse fields of biomedical investigation. This review serves to characterize the current understanding of biological sex differences between female and male lower urinary tracts, while identifying areas for future research. First, the differences in overall cell populations are discussed in the detrusor smooth muscle, urothelium, and trigone.","[3.0, 3.0, 5.0, 5.0, 5.0]",Medicine,train,4.2,news,http://ct.moreover.com/?a=37467004525&p=1pl&v=1&x=98jwd8q8ykw-BTcH2Zm4Mg
10.1038/s41467-019-08382-z,Medicine_250,These interactions help Hel2 identify flaws in protein formation.,3 ) and associated mRNAs (Fig.,"This clears the way for further proteins to be produced. These interactions help Hel2 identify flaws in protein formation. When researchers removed the parts of Hel2 in direct contact, this prevented the destruction of faulty proteins, showing that these contacts are important for the mechanism.","2) , revealing that Hel2 binds both the small subunit of translating ribosomes ( Fig. 3 ) and associated mRNAs (Fig. 8) .","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=38442592628&p=1pl&v=1&x=6qnjJlZN_F0RgmqDHnl0dA
10.1039/c3cs60122f,Medicine_251,"First, labfolder and its peers should always promote the use of the electronic lab notebook as a principle, and not just their own specific solution.",They note that the knowledge that a laboratory notebook comprises can be critical for establishing evidence in support of intellectual property rights and for refuting claims of research misconduct.,"Besides simply creating an awesome product, I would highlight three things ELN companies can do to encourage uptake:





1. First, labfolder and its peers should always promote the use of the electronic lab notebook as a principle, and not just their own specific solution. I strongly believe that most electronic lab notebooks are superior to the paper version, and this is the message that we always transmit to the scientists that contact us.",119 He also presented a financial justification for electronic management of IP records. They note that the knowledge that a laboratory notebook comprises can be critical for establishing evidence in support of intellectual property rights and for refuting claims of research misconduct. 120 It is perhaps a sign of the times that this is one of only two publications in this survey to mention defence against claims of misconduct.,"[3.0, 3.0, 3.0, 2.0]",Medicine,train,2.75,news,http://ct.moreover.com/?a=37060720905&p=1pl&v=1&x=mJkzlHa3lmu5bv8uh9G1ig
10.1073/pnas.1704745114,Medicine_252,"This proved the scientists' theory that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, rather than constant environments and temperatures.","When cells communicated more readily (higher transport rates), continuous cold was incapable of flipping the switch (Fig.","The hormones that activate movement in the plant (in the case of germination) are similar to the decision-making center involved in movement in human brains. This proved the scientists' theory that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, rather than constant environments and temperatures. ""Our work has important implications for understanding how crops and weeds grow,"" said study author George Bassel of the University of Birmingham.","3F ) cold stimuli were capable of flipping the dormancy fate switch. When cells communicated more readily (higher transport rates), continuous cold was incapable of flipping the switch (Fig. 3G) , but, notably, a variable input did lead to the breaking of dormancy (Fig.","[3.0, 1.0, 3.0]",Medicine,train,2.333333333333333,news,http://www.natureworldnews.com/articles/38372/20170609/scientists-germinate-brain-plant-crops.htm
10.1016/j.nicl.2015.02.009,Medicine_253,Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task.,"Overall, however, these findings suggest that excess fMRI activation in the DG/CA3 is associated with a consistent profile of memory task impairment across all three aMCI cohorts.","""At the same time, it improves memory performance on a task that depends on the hippocampus."" Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task. The ideal dosing found in this clinical study matched earlier preclinical studies in animal models.","Overactivity in areas of activation localized anterior to posterior, as reported here and elsewhere in the context of the 3-judgment recognition task could reflect a relatively greater contribution of augmented pattern completion in anterior areas of activation with any excess activation reflecting a loss of pattern separation in DG contributing more in posterior areas of activation. Overall, however, these findings suggest that excess fMRI activation in the DG/CA3 is associated with a consistent profile of memory task impairment across all three aMCI cohorts. Importantly, no evidence was found in this study to support a beneficial compensatory role in cognition for excess hippocampal activation.","[1.0, 5.0, 2.0, 1.0, 3.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1073/pnas.1414221111,Medicine_254,"Researchers believe the unique mode of action of (+)-SJ733, combined the speed with which it kills the parasite, could hold hopes of widespread treatment.",(+)-SJ733 achieves this efficacy from exposure (AUC ED90 1.5 μM·h) similar to that of chloroquine (AUC ED90 3.1 μM·h) and superior to that of pyrimethamine (AUC ED90 5.2 μM·h) in the same model.,"Future research includes safety trials for the first human tests. Researchers believe the unique mode of action of (+)-SJ733, combined the speed with which it kills the parasite, could hold hopes of widespread treatment. Altering sodium levels in infected blood cells caused changes similar to those seen in aging cells.","The compound also had oral bioavailability of >65% in both rats (SI Appendix, SJ733 is an efficacious and safe orally active drug candidate. (+)-SJ733 achieves this efficacy from exposure (AUC ED90 1.5 μM·h) similar to that of chloroquine (AUC ED90 3.1 μM·h) and superior to that of pyrimethamine (AUC ED90 5.2 μM·h) in the same model. (B) (+)-SJ733 exhibits excellent exposure after oral administration in mouse, rat, and dog.","[5.0, 3.0, 3.0, 2.0]",Medicine,train,3.25,news,http://www.techtimes.com/articles/21756/20141208/new-compound-could-mean-the-end-for-malaria-parasite.htm
10.1377/hlthaff.2012.1030,Medicine_255,"""We were surprised to find greater variation in hospital cesarean rates among lower-risk women.","Cesarean delivery is much more costly than vaginal delivery ($12,739 versus $9,048 for private health insurers in 2010).","""We were surprised to find greater variation in hospital cesarean rates among lower-risk women. The variations we uncovered were striking in their magnitude, and were not explained by hospital size, geographic location, or teaching status,"" study lead author Katy Kozhimannil, an assistant professor at the university's School of Public Health, said in a school news release. ""The scale of this variation signals potential quality issues that should be quite alarming to women, clinicians, hospitals and policymakers,"" she added.Cesarean delivery is the most common surgery in the United States, performed on 1.67 million women each year.","19 The widespread use of cesarean delivery has important policy implications. Cesarean delivery is much more costly than vaginal delivery ($12,739 versus $9,048 for private health insurers in 2010). 20 Adverse outcomes and complications have substantial cost implications for delivery systems and health insurers, both public and private.","[2.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,news,http://www.webmd.com/baby/news/20130304/c-section-rates-vary-widely-at-us-hospitals
10.1016/j.ijnurstu.2014.02.007,Medicine_256,This is the first study of patient survival in ICUs to look at the numbers of doctors as well as nurses.,We found no evidence that the number of support staff working on the unit improves patients' survival chances even though their presence on the unit might have the effect of releasing clinical staff to care for patients.,"Recent catastrophic failures such as events at Mid-Staffordshire have highlighted the importance of staffing levels to patient survival, and this study has reinforced that message."" This is the first study of patient survival in ICUs to look at the numbers of doctors as well as nurses. Professor West says that doctors and nurses work closely together and function as a team on ICUs more than on other wards: ""Future studies need to see the whole picture and examine how the multi-disciplinary team works together.""","Nurses and doctors do seem to make a difference to patient outcomes in ICU. We found no evidence that the number of support staff working on the unit improves patients' survival chances even though their presence on the unit might have the effect of releasing clinical staff to care for patients. In this study, clear support emerged for the effect of workload.","[3.0, 2.0, 4.0, 2.0, 3.0]",Medicine,train,2.8,news,http://www.healthcanal.com/public-health-safety/49249-low-icu-staffing-levels-affect-patient-survival.html
10.1016/j.immuni.2019.05.007,Medicine_259,"""We've established an understanding of the virus and how it changes, how the body's immune response targets it and how we can use that information to make a better vaccine.""","This antibody was present in appreciable amounts in the serum prior to vaccination, suggesting that it must have been elicited by an earlier HuNoV infection.","The technology, developed by co-author George Georgiou, was used to discover the key antibody in the study and the approach is applicable to a variety of highly variable bacteria and viruses. ""This study addresses a fundamental problem in norovirus disease development that could have wide-ranging impact on global health,"" says Lindesmith. ""We've established an understanding of the virus and how it changes, how the body's immune response targets it and how we can use that information to make a better vaccine.""","In donor A, we showed that the most dramatically backboosted blockade antibody following vaccination is capable of blocking VLP-HBGA binding of all examined GII.4 strains circulating between 1987 and 2015 and is potently neutralizing in the human intestinal enteroid culture system. This antibody was present in appreciable amounts in the serum prior to vaccination, suggesting that it must have been elicited by an earlier HuNoV infection. These findings reveal that HuNoV infection can induce broad blockade and neutralizing antibodies and that these antibodies can be boosted by vaccination .","[3.0, 2.0, 3.0, 1.0]",Medicine,train,2.25,news,http://ct.moreover.com/?a=39492021503&p=1pl&v=1&x=pWvt65L5t0zbViDRQJNp1g
10.1001/jamainternmed.2016.0157,Medicine_26,"Systolic BP readings with the IBP app were within 5 mm Hg of the standard measurement 24% of the time, within 10 mm Hg 44% of the time, and within 15 mm Hg 59% of the time; diastolic BP readings were within 55 mm Hg of the standard measurement 26% of the time, within 10 mm Hg 48% of the time, and 15 mm Hg 70% of the time.","IBP systolic BP readings were within , 10, and 1 mm Hg of the standard BP measurement 24%, 44%, and 9% of the time, respectively, whereas respective proportions for diastolic BP were 26%, 48%, and 70%, correlating with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring.","The researchers found that higher BP measures were underestimated and lower BP measures were overestimated. Systolic BP readings with the IBP app were within 5 mm Hg of the standard measurement 24% of the time, within 10 mm Hg 44% of the time, and within 15 mm Hg 59% of the time; diastolic BP readings were within 55 mm Hg of the standard measurement 26% of the time, within 10 mm Hg 48% of the time, and 15 mm Hg 70% of the time. These measurements correlated with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring.","IBP underestimated higher BPs and overestimated lower BPs (Figure) . IBP systolic BP readings were within , 10, and 1 mm Hg of the standard BP measurement 24%, 44%, and 9% of the time, respectively, whereas respective proportions for diastolic BP were 26%, 48%, and 70%, correlating with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring. Spearman ρ was 0.44 (P < .001) for systolic BP and 0.41 (P < .001) for diastolic BP.","[4.0, 4.0, 4.0, 3.0, 4.0]",Medicine,train,3.8,news,http://www.oncologynurseadvisor.com/instant-blood-pressure-mobile-app-fails-validation-study/article/484459/
10.1016/j.jalz.2018.06.2856,Medicine_260,"""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye.""",Future directions: Caregivers and health-care workers should facilitate adequate ophthalmic care for older individuals at risk of dementia.,"""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" The possible connections need more study.",3. Future directions: Caregivers and health-care workers should facilitate adequate ophthalmic care for older individuals at risk of dementia. Eye care providers should be aware of increased AD risk in certain ophthalmic conditions.,"[3.0, 1.0, 2.0, 3.0]",Medicine,train,2.25,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1038/s41396-017-0042-4,Medicine_263,This could be the reason why genetically identical viruses can be found in very different environments in the planet.,"The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere.","Researchers also found that billions of viruses and tens of millions of bacteria are deposited per square meter each day. This could be the reason why genetically identical viruses can be found in very different environments in the planet. ""This preponderance of long-residence viruses traveling the atmosphere likely explains why -- it's quite conceivable to have a virus swept up into the atmosphere on one continent and deposited on another,"" says virologist Curtis Suttle of the University of British Columbia.","Therefore, these relationships between the size fractions of the organic aerosols and the virus and bacteria deposition rates could be also determined by the origin of air masses. The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere. This provides a mechanism for maintaining the very high diversity of viruses, as well as bacteria observed at a local level but constrained globally, consistent with a seedbank model.","[5.0, 5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,news,http://ct.moreover.com/?a=33241815989&p=1pl&v=1&x=QWG0hS8aFIKDkjtM81Puow
10.1098/rsif.2012.0838,Medicine_264,"""But usually frogs would avoid overhanging surfaces to avoid such difficult sprawling positions.""","After further rotation, the frogs changed their posture again, with limbs being splayed out much further, sometimes to their maximum extension.","The easiest way to peel tape away from a surface is by pulling one corner away at the largest possible angle from the sticking surface; pulling the tape at a shallow angle makes it virtually impossible to get unstuck. ""This experiment shows the maximum adhesive force a frog can take,"" says Thomas Endlein, a biologist at the University of Glasgow, UK, who led the study. ""But usually frogs would avoid overhanging surfaces to avoid such difficult sprawling positions.""","During this rotation, the frog tended to change its posture in a characteristic way (figure 2 and the electronic supplementary material, video S1). After further rotation, the frogs changed their posture again, with limbs being splayed out much further, sometimes to their maximum extension. We often found gradual changes between these two categories, where legs were extended one after the other.","[3.0, 4.0, 2.0, 2.0, 4.0]",Medicine,train,3.0,news,http://www.scientificamerican.com/article.cfm?id=frogs-cling-to-and-peel-from-surfaces-just-like-adhesive-tape
10.1377/hlthaff.2018.05101,Medicine_265,"But underserved populations -- such as low-income, rural and Medicaid populations -- did not use video-based telehealth as widely as other demographic groups.",The use of telehealth increased dramatically in the period 2013-16 across all population groups.,"The use of video consultations was most common among higher income respondents and those who had difficulty leaving their homes. But underserved populations -- such as low-income, rural and Medicaid populations -- did not use video-based telehealth as widely as other demographic groups. The researchers identified this trend across the U.S., even in states with less restrictive telehealth policies -- suggesting that providers and patients will need incentives to adopt the service that go beyond removing regulatory restrictions.","[31] Demonstrating the role that telehealth can play in achieving the Triple Aim of improving quality and health outcomes while lowering the cost of care could prove to be a powerful incentive for increased uptake. The use of telehealth increased dramatically in the period 2013-16 across all population groups. While we found evidence that populations with limited mobility (such as Medicare beneficiaries younger than age sixty-five and people with selfreported physical or mental health concerns that limit their activities) were among the highest users, key underserved populations (including Medicaid, low-income, and rural populations) had significantly lower use of telehealth.","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=37884913467&p=1pl&v=1&x=MrQLspWtUsUM_TYVPtFo1w
10.1126/sciadv.1700581,Medicine_267,"advertisement

Sobering findings

The team's results suggest that by the end of the century under a business-as-usual scenario, rainfall in Jordan will decrease by 30 percent, temperatures will increase by 6 degrees Celsius, and the number and duration of droughts will double.","The latter two drought types indicate the potential additional manifestations of precipitation deficit, rising temperature, and land-use change.","The authors said this approach could better inform drought management by considering all vulnerabilities for people, agriculture and the environment. advertisement

Sobering findings

The team's results suggest that by the end of the century under a business-as-usual scenario, rainfall in Jordan will decrease by 30 percent, temperatures will increase by 6 degrees Celsius, and the number and duration of droughts will double. Flow from the Yarmouk River, an important source of water that flows from Syria, would decline by up to 75 percent.","Jordan cannot afford to be overly sanguine about the devastating consequences of droughts given preexisting regional vulnerabilities due to conflicts, immigration, dependence on transboundary river flow, and limited mitigation options . The latter two drought types indicate the potential additional manifestations of precipitation deficit, rising temperature, and land-use change. In both cases, Jordan receives a small fraction (about one-third) of transboundary flow than it relied upon in the prewar period 1980-2010.","[4.0, 5.0, 2.0, 3.0]",Medicine,train,4.0,news,https://www.sciencedaily.com/releases/2017/08/170830202128.htm
10.1111/gcb.13276,Medicine_268,"""We want this index to be used to predict how corals might react to future bleaching events.","Because we cannot eliminate effects of intrinsic factors on taxon-sBRI j (e.g., a site may contain mostly bleaching-susceptible coral taxa), P ext is the upper bound of the true variance due to extrinsic factors, and it is expected to increase in accuracy for sites with diverse bleaching responses (i.e., in the limit of a high number of taxa per site n, Eqns 17-19).","""Using very large data sets, we have teased out valuable information that will help researchers identify global trends and learn about individual corals,"" says coauthor Vadim Backman, professor of biomedical engineering. ""We want this index to be used to predict how corals might react to future bleaching events. The index will be available online, so that data on corals can be added as they become available, making the tool even more robust.","The effect of extrinsic factors P ext was found by correlation between BRI j and taxon-sBRI j (Eqn 17). Because we cannot eliminate effects of intrinsic factors on taxon-sBRI j (e.g., a site may contain mostly bleaching-susceptible coral taxa), P ext is the upper bound of the true variance due to extrinsic factors, and it is expected to increase in accuracy for sites with diverse bleaching responses (i.e., in the limit of a high number of taxa per site n, Eqns 17-19). We estimated the effect of extrinsic factors P ext by correlation between BRI j and taxon-sBRI j (Eqn 17) for sites with two (most conservative estimate) and increasingly higher (n up to 44) numbers of taxa.","[1.0, 1.0, 4.0, 4.0]",Medicine,train,4.0,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1073/pnas.1620079114,Medicine_269,"""Taken together,"" she said, ""these data suggest that plasma erythritol may not simply reflect elevated blood glucose, but rather may signal or lead to metabolic changes that cause weight gain and/or diabetes.","5346; SI Appendix, Table S4 ).","Knowing how the body makes sugar alcohols, she said, opens an array of new possibilities for treatment and prevention of heart disease and Type 2 diabetes. Young adults who exhibited central adiposity gain over the course of 35 weeks had plasma erythritol levels 15-times higher at baseline than those with stable adiposity over the same period. ""Taken together,"" she said, ""these data suggest that plasma erythritol may not simply reflect elevated blood glucose, but rather may signal or lead to metabolic changes that cause weight gain and/or diabetes.","Valine and leucine concentration differences reached the nominal P value threshold, but not the FDR threshold, and isoleucine concentration differences were consistent in direction, although not statistically significant (P = 0.0620, FDR = 0. 5346; SI Appendix, Table S4 ). The meso-erythritol concentration was 20.6-fold greater (95% CI: 19.84, 21.41) in the higher glycemia group [105.6 (SE = 1.4) vs. 5.1 (SE = 0.1) μmol/L; P = 0.0024].","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=40332840581&p=1pl&v=1&x=pkcSn_o-Swy8HkWKnlFErg
10.1038/s41467-017-01957-8,Medicine_27,"Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off.","Interestingly, the predator diversity does not monotonically increase with prey diversity due to the dynamical trade-off.","In contrast, if the predator cannot adapt, the prey requires fewer resources for defence and can invest more in producing progeny"", explains Becks. Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off. The ciliates thus develop fewer different types in order to adapt to bacterial associations and biofilms.","This ultimately leads to a lower prey diversity compared to only prey evolution. Interestingly, the predator diversity does not monotonically increase with prey diversity due to the dynamical trade-off. Together, our experimental and theoretical results show that dynamical trade-offs arise and significantly affect the evolution and maintenance of intraspecific diversity.","[3.0, 4.0, 4.0, 3.0]",Medicine,train,3.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.1038/s41598-018-35253-2,Medicine_270,A hydrologically connected geothermal area means the methane can escape to the atmosphere rather than being trapped beneath the ice.,"This mass balance approach to calculating an evasive methane flux along the stream assumes minimal dilution, and no in-stream methanotrophy.","This may encourage greater connectivity with volcanic and geothermal areas buried beneath the ice. A hydrologically connected geothermal area means the methane can escape to the atmosphere rather than being trapped beneath the ice. ""[Another consequence could be that] as ice thins, this releases pressure on volcanic and geothermal systems beneath, and will likely drive an increase in eruptive activity and heat fluxes.","This equated to an evasive flux of 41 tonnes of methane to the atmosphere per day (32 M CH 4 m −2 day −1 as an area-weighted flux from stream to atmosphere). This mass balance approach to calculating an evasive methane flux along the stream assumes minimal dilution, and no in-stream methanotrophy. Both are valid assumptions given the minimal input of additional meltwater between upstream and downstream sampling points, the minimal production/consumption of methane in the proglacial sediments (Table S1) , and the limited change in isotopic composition of aqueous methane ( Table 1 ).","[3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=37747037897&p=1pl&v=1&x=25zujygYqDoju4-7l9c6zQ
10.1177/0141076814565942,Medicine_271,"""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world,"" Frisch concluded, ""our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""","Overall, the risk of hyperkinetic disorder was not elevated among ritually circumcised boys in the first 0-4 years of life (HR ¼ 0.99; 95% CI: 0.43-2.29) or in the 5-to 9-year age group (HR ¼ 1.27; 95% CI: 0.95-1.71) ( Table 2) .","The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency. At any rate, the findings may hold great promise for other countries to adopt formal anesthetic protocol to avoid, or at least minimize, the pain children experience. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world,"" Frisch concluded, ""our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""","Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys. Overall, the risk of hyperkinetic disorder was not elevated among ritually circumcised boys in the first 0-4 years of life (HR ¼ 0.99; 95% CI: 0.43-2.29) or in the 5-to 9-year age group (HR ¼ 1.27; 95% CI: 0.95-1.71) ( Table 2) . Among boys in Muslim families, risk of hyperkinetic disorder did not depend on the boys' foreskin status (HR ¼ 1.08; 95% CI: 0.77-1.52).","[3.0, 2.0, 2.0]",Medicine,train,2.333333333333333,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1001/jama.2015.1693,Medicine_273,A measure of disability worsened in more patients in the stent group than in the medical group.,"Moreover, the high stenting event rate may have been related to the current device's technical limitation, given the inherent first-generation device's design imperfections, which requires future iterations to enhance the safety and success of newer stent technology.","Thirty day all-cause death was 3 of 58 patients (5.2 percent) in the stent group and 0 in the medical group. A measure of disability worsened in more patients in the stent group than in the medical group. ""These findings do not support the use of a balloon-expandable stent for patients with intracranial arterial stenosis,"" the authors conclude.","26 Equating stenting for the purpose of cerebral aneurysm coiling to stenting for purpose of intracranial stenosis may have not been the best parameter to assure adequate operator experience, but we do not have enough sample size to ascertain its contribution to the worse outcome. Moreover, the high stenting event rate may have been related to the current device's technical limitation, given the inherent first-generation device's design imperfections, which requires future iterations to enhance the safety and success of newer stent technology. Furthermore, periprocedural factors should be evaluated such as timing of the stenting, best anesthesia choice, as well as best blood pressure management following luminal reconstitution.","[2.0, 2.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2015/03/150324120611.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamasurg.2014.2253,Medicine_274,"Regarding its limitations, Chang says the study doesn't directly compare survival among those who did and didn't get PTR, as the data available in SEER doesn't permit such evaluation without significant risk of bias.",Median relative survival rate improved from 8.6% in 1988 to 17.8% in 2009 (P < .001); the annual percentage change was 2.18% in 1988-2001 and 5.43% in 1996-2009 (P < .001).,"Independent of receiving PTR, the researchers also found that the median relative survival rate of metastatic colon cancer patients improved from 8.6 percent in 1988 to 17.8 percent in 2009. Regarding its limitations, Chang says the study doesn't directly compare survival among those who did and didn't get PTR, as the data available in SEER doesn't permit such evaluation without significant risk of bias. ""Our findings tell us that it is increasingly recognized that chemotherapy may be safely given to patients with tumors intact,"" he says.","Factors associated with primary tumor resection were age younger than 50 years, female sex, being married, higher tumor grade, and presence of colon tumors. Median relative survival rate improved from 8.6% in 1988 to 17.8% in 2009 (P < .001); the annual percentage change was 2.18% in 1988-2001 and 5.43% in 1996-2009 (P < .001). Despite the decreasing primary tumor resection rate, patient survival rates improved.","[2.0, 2.0, 3.0, 4.0, 2.0]",Medicine,train,2.6,news,http://www.healthcanal.com/cancers/59151-md-anderson-study-finds-patients-with-metastatic-colorectal-cancer-having-less-surgery-yet-survival-rates-improving.html
10.1073/pnas.1403984111,Medicine_275,CITES' data gave the study's authors a large-scale estimate of elephant populations across the African continent.,"Preliminary data from 2013 suggests regional and continental offtake levels were slightly lower to those reported for 2012, but still unsustainable.","A decade ago, that number was 25 percent, according to the AP. CITES' data gave the study's authors a large-scale estimate of elephant populations across the African continent. ""I think it's the only quantitatively-based estimate out there,"" said George Wittemyer, the lead author and a professor at Colorado State University, according to National Geographic.","3) , although site-specific results differed between the two methods. Preliminary data from 2013 suggests regional and continental offtake levels were slightly lower to those reported for 2012, but still unsustainable. Survey and PIKE-based modeling estimates of annual population trends were correlated (empirical results: Pearson's r = 0.675, P < 0.001; model results: Pearson's r = 0.372, P = 0.024), with the empirical-based result averaging 0.33% slower growth (SI Materials and Methods).","[1.0, 1.0, 1.0, 2.0, 1.0]",Medicine,train,1.2,news,http://www.usnews.com/news/newsgram/articles/2014/08/19/poachers-exhausting-elephant-population
10.1038/s41467-018-06108-1,Medicine_276,"With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex.",A similar level of difference in neutral mutations between the polyploid and diploids was found for highly expressed genes.,"With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex. Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions. ""With these results, we have demonstrated on a molecular-genetic level that genome duplications can positively affect the adaptability of organisms,"" says plant scientist Timothy Paape.","For genes with low expression, the polyploid subgenomes had about 10% more neutral mutations compared with the lowly expressed genes in the diploid species. A similar level of difference in neutral mutations between the polyploid and diploids was found for highly expressed genes. Overall, our results are consistent with expectations of relaxed constraint on genes with low expression and stronger purifying selection on highly expressed genes 46 in all three species.","[3.0, 1.0, 3.0]",Medicine,train,2.333333333333333,news,http://ct.moreover.com/?a=37204299584&p=1pl&v=1&x=jPnch-e_YD0TBwdpam4EyA
10.1001/jama.2018.20578,Medicine_277,"Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death.","27 However, the use of PPIs was inconsistently reported in the studies included in this analysis.","The results showed that:

Aspirin use was associated with an 11% lower risk of cardiovascular events. Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death. Aspirin use was associated with a 43% of major bleeding events, compared to those who did not take it.","34 The role of additional measures to reduce the potential harms of long-term aspirin use is not clear from the present study. 27 However, the use of PPIs was inconsistently reported in the studies included in this analysis. This finding is in contrast to an individual patient data meta-analysis of primary and secondary prevention aspirin trials that demonstrated a % reduction in cancer mortality associated with aspirin use.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,https://www.sciencedaily.com/releases/2019/01/190122114950.htm
10.1001/jamaoncol.2018.3701,Medicine_28,"Estimated Medicare Cost for Prostate Cancer Care in Older Men

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Key Points For men diagnosed in 2004, 2005, 2006, and 2007, the total 3-year cost for treating and screening each group was estimated to be $1.2 billion.","If we were to scale up our per-person cost to the national level using this more recent incidence data, the total 3-year costs to Medicare for diagnosing prostate cancer in men 70 years or older would be $1 billion, a decrease of approximately $200 million relative to the earlier incidence rates.","Estimated Medicare Cost for Prostate Cancer Care in Older Men

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Key Points For men diagnosed in 2004, 2005, 2006, and 2007, the total 3-year cost for treating and screening each group was estimated to be $1.2 billion. The median per-patient cost within 3 years after prostate cancer diagnosis was $14,453, with treatment costs accounting for 73% of that total. The researchers estimated a cost savings of $320 million per year for Medicare if patients who have a Gleason score of 6 choose active surveillance.","29, 30 The age groups with the largest declines were ages 70 to 74 years (a decrease of 112 men per 100 000) and 75 to 79 years (a decrease of 120 men per 100 000). If we were to scale up our per-person cost to the national level using this more recent incidence data, the total 3-year costs to Medicare for diagnosing prostate cancer in men 70 years or older would be $1 billion, a decrease of approximately $200 million relative to the earlier incidence rates. Third, active surveillance has become a standard option for men with Gleason scores of 6 or lower.","[3.0, 3.0, 4.0, 3.0]",Medicine,train,3.25,news,http://ct.moreover.com/?a=37161484598&p=1pl&v=1&x=LLy33mp4g8e_fImU9SDVlg
10.1016/j.bodyim.2016.09.005,Medicine_280,This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better.,"Rather, this explanation posits that Barbie's thin-ideal promoting messages are stronger when Barbie is depicted in a way that draws attention to her physical attributes, rather than the functionality of her body.",This was not the first time researchers claim Barbie dolls affect young girls' body image. This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better. The researchers suggested parents should emphasize and discuss what entails having a healthy body with their little girls so that they can develop good body image concepts.,"On the contrary, found that when referring to Barbies, girls still commented on appearance-related attributes other than body shape such as hair and facial features. Rather, this explanation posits that Barbie's thin-ideal promoting messages are stronger when Barbie is depicted in a way that draws attention to her physical attributes, rather than the functionality of her body. Given that a focus on physical functional ability over appearance is thought to contribute to lower body image concern , it may be that focusing on a Barbie's ability to move around and perform tasks could provide a protective effect against appearance-centric messages.","[3.0, 5.0, 2.0, 3.0, 3.0]",Medicine,train,3.2,news,http://www.parentherald.com/articles/97873/20170130/barbie-dolls-harm-little-girls-body-image-experts-advise-parents.htm
10.1186/s13059-018-1434-0,Medicine_281,"""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer.","Of these pathways, the 12 members that were under the strongest negative selection (d N /d S < 0.5) were specifically enriched in glucose transport and metabolism (""facilitative Na + -independent glucose transporters"" and ""glucose metabolism;"" both Q < 0.05).","Their results challenge the most extended paradigm of an exclusive role of positive selection in cancer evolution. ""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer. ""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes.","Three Reactome pathways related to molecular transport were enriched among the negatively selected genes ( Fig. Of these pathways, the 12 members that were under the strongest negative selection (d N /d S < 0.5) were specifically enriched in glucose transport and metabolism (""facilitative Na + -independent glucose transporters"" and ""glucose metabolism;"" both Q < 0.05). Specifically, five of the 12 genes, GCK, SLC2A1","[3.0, 2.0, 4.0, 2.0, 2.0]",Medicine,train,2.6,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1098/rsbl.2014.0993,Medicine_282,"Although the light of the half moon would likely be sufficient to illuminate the pollen, the full moon alone remains up throughout the entire night, so the researchers think that E. foeminiea maximizes the effect for efficiency.",The moon may further be crucial for pollinator attraction.,"That display likely acts as a homing beacon for insects, including the flies and moths that the researchers observed alighting on E. foeminiea that evening. Although the light of the half moon would likely be sufficient to illuminate the pollen, the full moon alone remains up throughout the entire night, so the researchers think that E. foeminiea maximizes the effect for efficiency. While some pollen drops did appear during the full moons of August and September, there were significantly fewer cones, suggesting that E. foeminiea, like its relatives, peaks in summer.","This fits well with our field sites in the Balkans, where a cloudy sky is rare in the summer and no high trees shade the environment. The moon may further be crucial for pollinator attraction. While investigated species of Gnetum emit easily detectable scent (C. Rydin 2014, personal observation and ), Ephedra does not.","[4.0, 4.0, 4.0, 4.0]",Medicine,train,4.0,news,http://www.smithsonianmag.com/science-nature/wereplant-releases-its-pollen-by-light-full-moon-180954827/
10.1186/s12944-018-0743-3,Medicine_283,Circuit training is also a great way to improve your muscular endurance and strength.,"In conclusion, I observed how circuit training at home can improve the calcaneus QUS status, such as QUS-SI, QUS-SOS, and QUS-BUA, as well as build muscle while losing fat mass through easy sports activities among young females.","The benefits of circuit training

When it comes down to it, the benefits of circuit training are to burn fat and build muscle, Ryan says. Circuit training is also a great way to improve your muscular endurance and strength. Circuit training helps with building muscular endurance because there aren't any rests between exercises; you go from one move to the next.","Third, studies involving both sexes may be needed to clarify the sex-based differences in the effect of such exercise on the calcaneus QUS status. In conclusion, I observed how circuit training at home can improve the calcaneus QUS status, such as QUS-SI, QUS-SOS, and QUS-BUA, as well as build muscle while losing fat mass through easy sports activities among young females. These findings suggest that circuit training can help females attain significantly greater bone mass and muscle mass and may reduce their risk of osteoporosis or cardiovascular disease in later life.","[4.0, 3.0, 4.0, 4.0, 4.0]",Medicine,train,3.8,news,http://ct.moreover.com/?a=39028000354&p=1pl&v=1&x=rNZIkXnItgXmLxg4R0B21g
10.1007/s10803-017-3154-9,Medicine_285,Children and teens living with married caregivers were slightly less likely to need hospital care than those living with only one adult caregiver.,"However, there were significant differences in caregiver marital status (χ 2 (2) = 15.8, p < 0.0001), with significantly more caregivers in the AIC sample being unmarried or without domestic partnerships (χ 2 (1) = 15.2, p < 0.0001).","And those with high scores on a scale of autism symptom severity had a slightly increased risk, the investigators found. Children and teens living with married caregivers were slightly less likely to need hospital care than those living with only one adult caregiver. The researchers said that's probably not about family structure or stability but more likely owes to the resources available to care for a very needy child.","Within both samples, the majority of participants resided in the family home (χ 2 (1) = 4.8, p = 0.05). However, there were significant differences in caregiver marital status (χ 2 (2) = 15.8, p < 0.0001), with significantly more caregivers in the AIC sample being unmarried or without domestic partnerships (χ 2 (1) = 15.2, p < 0.0001). No significant group differences were observed in household income (χ 2 (3) = 14.3, p = 0.003) after correcting for multiple comparisons.","[4.0, 2.0, 2.0, 2.0, 2.0]",Medicine,train,2.4,news,http://healthmedicinet.com/news/study-explains-hospitalization-odds-for-autistic-youth/
10.1093/gerona/glt162,Medicine_287,My suspicion is that many people who respond to surveys by saying they expect to work until age 70 or beyond haven't really thought through the implications of that decision.,"Taken together, these additional findings suggest that this potential bias did not yield a significant effect on combined work and housework limitation outcomes, although some possible underreporting of work limitations among the oldest age groups remains a limitation of the analysis.","So, the ""work longer"" strategy might be physically possible for large numbers of older people. My suspicion is that many people who respond to surveys by saying they expect to work until age 70 or beyond haven't really thought through the implications of that decision. With so many issues involved, that's a question for another day.","In two supplemental analyses, we found that the separate rates of housework limitations and work limitations by age group were fairly similar, and that the proportion of individuals with limitations in social, recreational, or family activities (another MEPS variable) rose even less steeply with increasing age than work or housework limitations. Taken together, these additional findings suggest that this potential bias did not yield a significant effect on combined work and housework limitation outcomes, although some possible underreporting of work limitations among the oldest age groups remains a limitation of the analysis. A substantial proportion of individuals in every age group report their health as ""excellent"" or ""very good"": 48% among those aged 51-54, falling gradually to 28% among those aged 85 and older ( Figure 2 ).","[2.0, 2.0, 1.0]",Medicine,train,1.6666666666666667,news,http://www.cbsnews.com/news/how-long-could-you-delay-retirement/
10.1073/pnas.1515528113,Medicine_288,"More resources ""do lead to improvements in coverage,"" he said.","Although these data are currently the most detailed estimates available, they are potentially biased by not representing a random sample of the US population and by having been collected from clinical observations at regular follow-up appointments.","Furthermore, increased funding to states could improve vaccine coverage and public health, the researchers noted. More resources ""do lead to improvements in coverage,"" he said. ""In terms of number of cancers averted per vaccine, there are decreasing marginal returns in states that already have high coverage.","In addition, our findings that a vaccine dose has the greatest impact in states with lower coverage and that every state benefits from cooperative vaccination policies are direct consequences of interstate migration and therefore are robust to assumptions of dose efficacy. Although these data are currently the most detailed estimates available, they are potentially biased by not representing a random sample of the US population and by having been collected from clinical observations at regular follow-up appointments. However, any such biases do not affect our projections significantly, as demonstrated by our model validation.","[1.0, 1.0, 3.0, 3.0, 3.0]",Medicine,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/tL7ylLtvSRo/
10.1016/j.cub.2014.01.013,Medicine_289,"The method allows the researchers to look not just at naturally occurring toxins from spider (especially tarantula) venom, but also at subtle molecular variants.","These studies establish screening of t-toxin libraries of native and mutated toxins, which we term ''toxineering,'' as a generally applicable method for isolation of novel ion channel modifiers and for design of ion channel modifiers with altered target selectivity.","The toxineering technique developed by these researchers is conducive to this. The method allows the researchers to look not just at naturally occurring toxins from spider (especially tarantula) venom, but also at subtle molecular variants. By means of further experimentation, the investigators were even able to identify the sub-domains of the TRPA1 ion channel that were bound by the modified ProTx-I.","We found that ProTx-I inhibits both Na V and TRPA1 by binding to the S1-S4 gating domains of these distantly related 6-TM channels. These studies establish screening of t-toxin libraries of native and mutated toxins, which we term ''toxineering,'' as a generally applicable method for isolation of novel ion channel modifiers and for design of ion channel modifiers with altered target selectivity. They also suggest that ProTx-I will be a valuable pharmacological reagent for addressing the biophysical mechanisms of TRPA1 gating and the physiology and pathophysiology of TRPA1 function in nociceptors, as well as for potential clinical application in the context of pain and inflammation.","[4.0, 1.0]",Medicine,train,2.0,news,http://guardianlv.com/2014/03/venom-of-tarantula-for-use-as-painkiller/
10.1007/s10803-017-3154-9,Medicine_29,"""Our results underscore the importance of a multidisciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological and psychiatric, adaptive, sleep and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services,"" Righi and co-authors wrote in the study published in Journal of Autism and Developmental Disorders.","Our results underscore the importance of a multi-disciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological/ psychiatric, adaptive, sleep, and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services.","The strongest risk factors--disrupted sleep, having a mood disorder and living in a home with a single caregiver--are not necessarily associated with ASD. ""Our results underscore the importance of a multidisciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological and psychiatric, adaptive, sleep and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services,"" Righi and co-authors wrote in the study published in Journal of Autism and Developmental Disorders. By employing statistical analysis techniques, the researchers were able to isolate risk factors that were independently and significantly associated with the risk of hospitalization.","In spite of its limitations, the present findings reveal indicators that may be useful for identifying children and adolescents at greater risk of psychiatric hospitalization as well as offer potential targets for individual and family intervention aimed at reducing the likelihood of requiring acute psychiatric services. Our results underscore the importance of a multi-disciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological/ psychiatric, adaptive, sleep, and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services. Furthermore, our findings highlight the need to consider the child's functioning in the context of family resources and needs during assessment and treatment, and to provide adequate supports for caregivers.","[5.0, 5.0, 4.0, 5.0]",Medicine,train,4.75,news,http://healthmedicinet.com/news/study-of-kids-with-autism-identifies-hospitalization-risk-factors/
10.1073/pnas.1714896114,Medicine_290,"Microdroplets solve the phosphorylation problem in a relatively elegant way, in large part because they have geometry on their side.","In the microdroplets containing only D-ribose and uracil without phosphoric acid, ribosylation reaction products were not observed.","Microdroplets solve the phosphorylation problem in a relatively elegant way, in large part because they have geometry on their side. It turns out that water is mostly a problem when the phosphate is floating around inside a pool of water or a primitive ocean, rather than on its surface. They perfectly optimize the need for life to form in and around water, but with enough surface area for phosphorylation and other reactions to occur.","Thus, uridine also forms spontaneously at room temperature and atmospheric pressure in aqueous microdroplets. In the microdroplets containing only D-ribose and uracil without phosphoric acid, ribosylation reaction products were not observed. These results indicate that this reaction may follow a similar route to a salvage pathway in cells .","[1.0, 2.0, 2.0]",Medicine,train,1.6666666666666667,news,http://www.futurity.org/microdroplets-origins-of-life-1583692/
10.1377/hlthaff.2012.1030,Medicine_291,C-sections also cost more than vaginal deliveries.,"Across all hospitals in our analysis, the mean number of deliveries in 2009 was 1,378 and ranged from 100 (the minimum for our analysis) to 11,971 (Exhibit 3).","The pivot in payments is being made as the quality of maternity care in the United States comes under renewed scrutiny. C-sections also cost more than vaginal deliveries. In the Denver area, for instance, the average vaginal delivery costs $7,716 while the average C-section costs $14,274, according to 2019 data from the Health Care Cost Institute.","The mean rate of cesarean delivery among women with term, singleton, vertex pregnancies and no prior cesarean delivery was 12.0 percent, with fifteenfold variation, from a low of 2.4 percent to a high of 36.4 percent. Across all hospitals in our analysis, the mean number of deliveries in 2009 was 1,378 and ranged from 100 (the minimum for our analysis) to 11,971 (Exhibit 3). Small, medium, and large hospitals represented 22 percent, 30 percent, and 48 percent of our sample, and averaged 581, 1,151, and 1,926 deliveries, respectively.","[2.0, 1.0, 2.0, 2.0, 2.0]",Medicine,train,1.8,news,http://ct.moreover.com/?a=40237818568&p=1pl&v=1&x=UbIfZ6fwxC-SSLoUKpAuow
10.1126/science.1252496,Medicine_293,Westphal said the suspected interstellar particles are surprisingly diverse.,Five of the features are associated with native defects in the foil and are not impact craters.,"If confirmed, this would be the world's first sampling of contemporary interstellar dust. Westphal said the suspected interstellar particles are surprisingly diverse. A few particles splatted a little when they hit the collection panels because of their speed and the fact that some ended up hitting the aluminum foils between the softer aerogel tiles meant to capture the grains.","The nondetection of iron implies that either the original projectile was relatively iron-poor compared to Orion and Hylabrook, or that relatively little of the original projectile was retained in the track. Five of the features are associated with native defects in the foil and are not impact craters. Four of the impact craters contain residues with compositions inconsistent with spacecraft origin or native foil defects.","[1.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.4,news,http://www.cbsnews.com/news/specks-returned-from-space-may-be-alien-visitors/
10.1001/jama.2013.277165,Medicine_294,"These findings do not support the use of otamixaban for patients with NSTE-ACS undergoing planned early percutaneous coronary intervention,"" the authors conclude.","At that time, the rates of the primary efficacy outcome in the higher-dose otamixaban group was 4.7% (the one selected to go forward) and was 5.6% in the UFH-pluseptifibatide group (adjusted RR, 0.848; 95% CI, 0.662-1.087) but the lower-dose group fulfilled the prespecified criteria for futility with a RR of more than 1 (primary efficacy outcome, 6.3%; RR, 1.130; 95% CI, 0.906-1.408) and was discontinued.","Study anticoagulant was discontinued because of bleeding in 242 patients (4.7 percent) in the otamixaban group and in 95 patients (1.7 percent) in the UFH-plus-eptifibatide group. ""Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy. These findings do not support the use of otamixaban for patients with NSTE-ACS undergoing planned early percutaneous coronary intervention,"" the authors conclude.","The design of the TAO trial has been published. At that time, the rates of the primary efficacy outcome in the higher-dose otamixaban group was 4.7% (the one selected to go forward) and was 5.6% in the UFH-pluseptifibatide group (adjusted RR, 0.848; 95% CI, 0.662-1.087) but the lower-dose group fulfilled the prespecified criteria for futility with a RR of more than 1 (primary efficacy outcome, 6.3%; RR, 1.130; 95% CI, 0.906-1.408) and was discontinued. Events occurring among patients who received the discontinued otamixaban dose were not considered in primary outcome analyses, which pertained only to participants randomized to the higher dose of otamixaban vs UFH plus eptifibatide, not to the low-dose otamixaban group.","[3.0, 4.0, 4.0, 2.0, 5.0]",Medicine,train,3.6,news,http://www.sciencedaily.com/releases/2013/09/130901153354.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1613193114,Medicine_295,"""This means that climate change adaptation is going to be more expensive than we thought.","However, because most of the high-peak days are generated by warmer temperatures, the upward shift of the temperature distribution has a corresponding effect on the distribution of peak load days, driving the second mode higher under RCP4.5 and higher still under RCP8.5.","They also have a message for policymakers. ""This means that climate change adaptation is going to be more expensive than we thought. And so mitigation efforts become more valuable-more worthwhile-because they can prevent these costs,"" said Hausman, who is co-author of the study that appears in the Proceedings of the National Academy of Sciences.","Note that the low-use mode does not shift substantially for either ERCOT or PJM; this is because the number of days with moderate heating needs decreases even as the number of days with moderate cooling needs increases. However, because most of the high-peak days are generated by warmer temperatures, the upward shift of the temperature distribution has a corresponding effect on the distribution of peak load days, driving the second mode higher under RCP4.5 and higher still under RCP8.5. PJM shows a similar but less pronounced effect, with a second mode beginning to emerge under the RCP8.5 scenario.","[2.0, 4.0, 3.0, 1.0]",Medicine,train,2.5,news,http://healthmedicinet.com/news/electricity-costs-a-new-way-theyll-surge-in-a-warming-world/
10.1177/0141076814565942,Medicine_297,"The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency.",This means that our study missed the few traditional Jewish circumcisions in Denmark.,"That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces. The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency. At any rate, the findings may hold great promise for other countries to adopt formal anesthetic protocol to avoid, or at least minimize, the pain children experience.","Specifically, using data from nine countries, Bauer and Kriebel 31 observed that with each 10% increase in a population's neonatal circumcision rate, the estimated prevalence of ASD increased significantly by 2.01 per 1000 boys. This means that our study missed the few traditional Jewish circumcisions in Denmark. If not properly addressed, any association between ritual circumcision and ASD risk could theoretically be due to other factors that might differ between boys in Muslim and non-Muslim families.","[1.0, 2.0, 1.0, 1.0, 2.0]",Medicine,train,1.4,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1002/ejhf.69,Medicine_298,"However, the trial found that empagliflozin conferred an overall cardiovascular death risk reduction of 38%, compared with placebo.",Mortality and hospitalization risk was higher among participants with reduced ejection fraction versus preserved ejection fraction for participants with preceding vascular disease (HR 1.,"""This was not a heart failure study, so we don't know what their New York Heart Association class was, or the details of their baseline HF treatment in the minority of patients who were enrolled who had a history of HF,"" Dr. Butler cautioned. However, the trial found that empagliflozin conferred an overall cardiovascular death risk reduction of 38%, compared with placebo. When the researchers assessed the impact of treatment on all modes of cardiovascular death, they found that death from heart failure benefited the most (hazard ratio, 0.32; P = .0008), while sudden death benefited as well.","Proportion of participants with reduced versus preserved left ventricular ejection fraction was 45.0% and 55.0% for those with preceding vascular disease and 33.0% vs. 67.0% for those without preceding vascular disease (P=0.040). Mortality and hospitalization risk was higher among participants with reduced ejection fraction versus preserved ejection fraction for participants with preceding vascular disease (HR 1. In this study, consistent with previous reports, we found that vascular disease was an independent predictor of HF in older adults and that the majority of incident cases occurred among individuals with some form of vascular disease 35 .","[1.0, 1.0, 2.0]",Medicine,train,1.3333333333333333,news,http://ct.moreover.com/?a=38228224591&p=1pl&v=1&x=VEvBLGqbB4NvvfbrYC9-sA
10.1001/jamasurg.2018.0672,Medicine_3,"Of the 704 patients, 60.7, 31.7, and 7.7 percent reported sufficient, problematic, and inadequate FHL, respectively.","Most (n = 427 [60.6%]) of the 704 patients undergoing day surgery reported sufficient FHL, 223 (31.7%) reported problematic FHL, and 54 (7.7%) reported inadequate FHL.","Of the 704 patients, 60.7, 31.7, and 7.7 percent reported sufficient, problematic, and inadequate FHL, respectively. The researchers found that the inadequate and problematic FHL groups had a global score of SwQoR that indicated poor recovery (37.4 and 22.9, respectively). The difference in the global score of SwQoR between inadequate and sufficient FHL (37.4 and 17.7) was statistically significant.","Of these patients, 418 (59.4%) were women and 286 (40.6%) were men. Most (n = 427 [60.6%]) of the 704 patients undergoing day surgery reported sufficient FHL, 223 (31.7%) reported problematic FHL, and 54 (7.7%) reported inadequate FHL. There were no statistical differences between the 3 groups in age, sex, type of anesthesia and surgery, or ASA classification ( Table 1) .","[5.0, 5.0, 3.0, 5.0, 4.0]",Medicine,train,4.4,news,http://ct.moreover.com/?a=33900191633&p=1pl&v=1&x=U2NKEgQRLXmLRbYHpHEUVQ
10.1001/jama.2018.20578,Medicine_30,"With a daily aspirin, 57 rather than 61 people per 10,000 would be expected to suffer a heart attack or stroke; at the same time, 23 rather than 16 people per 10,000 would experience severe bleeding, on average.","In this meta-analysis of 13 trials enrolling 164 225 participants without cardiovascular disease, aspirin use was associated with reductions in the composite cardiovascular outcome consisting of cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke.","That underlines how important it is not to start doing this until you've chatted to your doctor about it. With a daily aspirin, 57 rather than 61 people per 10,000 would be expected to suffer a heart attack or stroke; at the same time, 23 rather than 16 people per 10,000 would experience severe bleeding, on average. ""This seriously questions whether people who have not previously had heart attacks or strokes should be taking aspirin with the aim of reducing future cardiovascular events,"" Zheng told Lisa Rapaport at Reuters.","Aspirin use was associated with increased risk of major bleeding (HR, In this meta-analysis of 13 trials enrolling 164 225 participants without cardiovascular disease, aspirin use was associated with reductions in the composite cardiovascular outcome consisting of cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke. However, aspirin use was associated with an increased risk of major bleeding, intracranial bleeding, and major gastrointestinal bleeding with comparable absolute risk estimates.","[3.0, 2.0, 4.0, 5.0]",Medicine,train,3.5,news,http://ct.moreover.com/?a=38333931091&p=1pl&v=1&x=RFNXfRDC7W6ykWiKhqzpYQ
10.1146/annurev-publhealth-031914-122421,Medicine_300,The gap could make Latinos more vulnerable and potentially more expensive to treat than other racial and ethnic groups with better English language skills.,The findings are that Mexican-origin Latinos fare worse.,"""These services may become increasingly politically tenuous as undocumented populations account for higher proportions of clinic users over time,"" he said. The gap could make Latinos more vulnerable and potentially more expensive to treat than other racial and ethnic groups with better English language skills. The UCLA study also found recent analyses of states that were among the first to implement their own insurance marketplaces suggesting that reducing the number of people who were uninsured reduced mortality and improved health status among the previously uninsured.","These studies have highlighted the significant differences between Mexican-origin and non-Mexican-origin Latinos in terms of health care access and utilization, insurance coverage, health spending, and the utilization of preventive care, after adjusting for socioeconomic and demographic differences-such as age, income, health, insurance status, and region of residence, as well as other predisposing, enabling, and need factors . The findings are that Mexican-origin Latinos fare worse. These findings suggest that strengthening pathways to citizenship would substantially reduce the overall barriers to care experienced by undocumented Latinos.","[1.0, 3.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,news,http://www.sciencedaily.com/releases/2015/03/150319092222.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29
10.1016/j.stemcr.2018.03.019,Medicine_303,The researchers found that DNA methylations are erased in female iPS cells but not in male cells.,This highlights the importance of examining single-CpG-level DNA methylation during the reprogramming process.,"The differences between male and female iPS cells are most pronounced for one of the key processes in the field of epigenetics: DNA methylation, a modification that changes the activity of a DNA segment without changing its sequence. The researchers found that DNA methylations are erased in female iPS cells but not in male cells. ""Our study also indicates that the path towards iPS cells involves the use of specific control switches on DNA called enhancers,"" adds Dr Constantinos Chronis from UCLA.","We conclude that CpG-specific and reprogramming stage-specific changes in DNA methylation take place throughout female reprogramming. This highlights the importance of examining single-CpG-level DNA methylation during the reprogramming process. Within ESC super-enhancers during female cell reprogramming ( Figure 4B) , a large proportion of CpGs was constitutively hypomethylated (clusters 1 and 2).","[4.0, 4.0, 2.0, 1.0, 4.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1111/gcb.13526,Medicine_304,Cutting down on roots could produce additional carbon savings that the plant can invest towards boosting yield.,Significant increases in the magnitude predicted by the model were observed in the field both at current and elevated [CO 2 ] (Table 1 ; Fig.,"""The experiment indicates that that our model is conservative,"" Srinivasan said. Cutting down on roots could produce additional carbon savings that the plant can invest towards boosting yield. Alternatively, plants with fewer leaves are more water efficient, and thereby may be potentially drought tolerant.""","In practice, artificially decreasing investment in leaves by removing a proportion of the emerging leaves during seed fill in the field resulted in increased seed yield. Significant increases in the magnitude predicted by the model were observed in the field both at current and elevated [CO 2 ] (Table 1 ; Fig. An important benefit of having fewer canopy leaves is its associated lower crop water demand.","[1.0, 2.0, 1.0, 2.0, 3.0]",Medicine,train,1.8,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1038/nature12167,Medicine_305,SMO is important for proper growth in the early stages of mammalian development and animals with deficiencies in the activities of this protein develop severe deformities in the womb.,"In cilia, the activated SMO receptor induces the modification of GLI transcription factors into the active form, thereby inhibiting the processing of GLI transcription factors into a repressor form.","Potential Target for Drug Design

The work is also significant because the SMO protein itself is a potential target for drug design. SMO is important for proper growth in the early stages of mammalian development and animals with deficiencies in the activities of this protein develop severe deformities in the womb. The body reduces its need for SMO in adulthood, and its activity is usually curtailed.","Although the SMO receptor shares the seven-transmembrane helical fold, most of the conserved motifs for class A GPCRs are absent, and the structure reveals an unusually complex arrangement of long extracellular loops stabilized by four disulphide bonds. In cilia, the activated SMO receptor induces the modification of GLI transcription factors into the active form, thereby inhibiting the processing of GLI transcription factors into a repressor form. The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 1 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity.","[3.0, 4.0, 2.0, 2.0]",Medicine,train,2.75,news,http://www.healthcanal.com/medical-breakthroughs/38297-scripps-research-institute-scientists-find-dissimilar-proteins-evolved-similar-7-part-shape.html
10.1186/1742-2094-10-46,Medicine_306,The idea that treating inflammation will mitigate the symptoms of autism is in no way novel.,"We showed that mtDNA is significantly increased in the serum of young autistic children , who also had significantly increased serum level of NT ; this triggers mast cells to secrete mtDNA that acts as innate pathogen to stimulate mast cells and other immune cells, leading to auto-inflammation .","Finding the inflammation-response genes activated is a major piece of the autism puzzle the researchers feel. At that time, the incidence of autism was one in 166 children. The idea that treating inflammation will mitigate the symptoms of autism is in no way novel.","There is also support for increased oxidative stress and some mitochondrial (mt) defects at least in subgroups of patients with ASD . We showed that mtDNA is significantly increased in the serum of young autistic children , who also had significantly increased serum level of NT ; this triggers mast cells to secrete mtDNA that acts as innate pathogen to stimulate mast cells and other immune cells, leading to auto-inflammation . We believe that ASD originate from immune perinatal insults that activate ASD susceptibility genes leading to focal encephalitis ( Table 2) .","[2.0, 1.0, 2.0, 3.0, 4.0]",Medicine,train,2.4,news,http://www.inquisitr.com/1676403/researchers-inflammation-is-a-marker-for-autism-could-treating-inflammation-eliminate-symptoms/
10.1038/s41598-018-29793-w,Medicine_307,"As if that werenat weird enough, researchers further found that study participantsa noses fell into six different nasal microbiome subtypes.","The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection.","Well, as a turns out, your nose has a microbiome, too a and it might play a key role in how well you fight off colds. As if that werenat weird enough, researchers further found that study participantsa noses fell into six different nasal microbiome subtypes. These nasal microbiome types are linked to how bad your cold symptoms get, and how well you fight the virus off in the first place.","We found that nasal microbiotas of healthy adults in our study cohort grouped into six distinct clusters Staph, Cor/All, Mor, Hae, Ps/Mix, and Mixed, based on the predominant bacterial genera in the nasal microflora. The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection. Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation.","[3.0, 4.0, 3.0]",Medicine,train,3.333333333333333,news,http://ct.moreover.com/?a=37227743738&p=1pl&v=1&x=2zyW9bON3VHP6zbXr8qTXQ
10.1186/s40168-015-0071-z,Medicine_309,"""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said.","The aggregated secretor-fed infant samples were, on average, found to have significantly higher absolute levels of bifidobacteria (10 9 .0 /g feces versus 10","advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces. ""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said. Maternal secretor status is likely only one of the many factors that influence the infant gut microbiota, Lewis said.","Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05). The aggregated secretor-fed infant samples were, on average, found to have significantly higher absolute levels of bifidobacteria (10 9 .0 /g feces versus 10 7.7 /g feces, p < 0.001) ( Figure 3 ).","[2.0, 3.0, 1.0, 4.0]",Medicine,train,2.5,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s13229-018-0246-0,Medicine_31,"In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","In all three cities, new cases of autism were identified by the study in mainstream schools, reflecting current under-diagnosis.","In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","Results from Shenzhen and Jiamusi cities, where only mainstream data were available, prevalence is also in line with Western estimates. In all three cities, new cases of autism were identified by the study in mainstream schools, reflecting current under-diagnosis. Non-significant variation across different cities is seen indicating the need to explore potential variation of autism across diverse Chinese regions with large sample sizes to achieve a fully robust national picture.","[5.0, 5.0, 5.0, 2.0, 5.0]",Medicine,train,5.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1016/j.cell.2013.08.004,Medicine_310,"They show that if you block the activity of this gene in mice, they recover faster from disturbances in their daily light/dark cycle that were designed to simulate jet-lag.","Significantly, the clock genes Per1 and Per2 also contain conserved CREs, which mediate their light induction .","They show that if you block the activity of this gene in mice, they recover faster from disturbances in their daily light/dark cycle that were designed to simulate jet-lag. They identified around 100 genes that were switched on in response to light, revealing a sequence of events that retune the circadian clock. When they blocked the activity of SIK1, the mice adjusted faster to changes in light cycle.","The promoters of many previously identified light-responsive genes in the SCN including Fos, Nr4a1, Egr1, Egr3 , the MAP kinase phosphatase Dusp1 , and miRNAs miR-132 and miR-217 all contain a highly conserved CRE. Significantly, the clock genes Per1 and Per2 also contain conserved CREs, which mediate their light induction . Elevated PER1 and PER2 adjust the molecular-feedback loop of the circadian oscillator to the light/dark (LD) cycle.","[4.0, 1.0, 1.0, 4.0, 1.0]",Medicine,train,1.0,news,http://www.healthcanal.com/disorders-conditions/sleep/42414-jet-lag-study-reveals-why-time-changes-are-a-struggle.html
10.1016/j.cell.2015.07.058,Medicine_311,"""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea.",MR knockdown and Mirin have no effect on DDR phosphorylated substrates in uninfected and DE1-infected cells ( Figure 2C ).,"This means the virus is effectively ignored while the cell responds to the more massive alarm. ""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","Thus, the activation of global DDR signaling in WT-virus-infected cells is MRN independent and is not due to residual MRN expression or activity. MR knockdown and Mirin have no effect on DDR phosphorylated substrates in uninfected and DE1-infected cells ( Figure 2C ). Strikingly, in DE1B-55K/DE4-ORF3-infected cells MR knockdown, but not Mirin, induces the global phosphorylation of DDR substrates ( Figure 2C ).","[1.0, 2.0, 1.0]",Medicine,train,1.3333333333333333,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1002/oby.20610,Medicine_312,"The results show that home-schoolers were less likely to be obese than the traditionally-schooled kids, even though kids in both groups were getting the same amount of moderate to vigorous physical activity.","Traditional school status was associated with increased reported intake of trans fat (p=0.0136), total sugar (p=0.0342), added sugars (p=0.0164), calcium (p=0.0109), and decreased consumption of fiber (p=0.0408), and fruits and vegetables (p=0.0005).","""We found the opposite."" The results show that home-schoolers were less likely to be obese than the traditionally-schooled kids, even though kids in both groups were getting the same amount of moderate to vigorous physical activity. The calorie intakes were also similar, except at lunchtime.","No significant differences were detected between TSC and HSC with respect to the amount of time spent engaged in daily moderate to vigorous physical activity. Traditional school status was associated with increased reported intake of trans fat (p=0.0136), total sugar (p=0.0342), added sugars (p=0.0164), calcium (p=0.0109), and decreased consumption of fiber (p=0.0408), and fruits and vegetables (p=0.0005). Being traditionally schooled was also nearly significantly associated with increased energy intake (p=0.0584).","[3.0, 4.0, 2.0, 4.0, 4.0]",Medicine,train,3.4,news,http://www.sciencedaily.com/releases/2013/10/131017111406.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41590-018-0068-4,Medicine_313,These results suggest that TLR8 acts as a key switch for protective immune responses.,These results indicated that the recognition of bacterial viability was an essential driver of vaccine-induced T FH cell and antibody responses in vivo.,"Moreover, the scientists also found that patients carrying an activating TLR8 gene variant responded better to a live vaccine against tuberculosis, which resulted in improved protection against disease. These results suggest that TLR8 acts as a key switch for protective immune responses. ""These results may enable us to develop new vaccines that will combine the safety of modern subunit vaccines with the high efficacy of live vaccines.""","7g) , which demonstrated enhanced humoral immunity in response to the live vaccine. These results indicated that the recognition of bacterial viability was an essential driver of vaccine-induced T FH cell and antibody responses in vivo. A TLR8 polymorphism is associated with vaccine protection in humans.","[2.0, 4.0, 1.0, 3.0, 4.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=33723683656&p=1pl&v=1&x=R9OQAdHcxos4adubuX4cGg
10.1016/j.stemcr.2018.03.019,Medicine_314,Working with iPS cells has numerous advantages compared with other methods.,These observations might explain some of the changes described in a recent study of DNA methylation during reprogramming that did not examine the state of the X chromosome .,"Working with iPS cells has numerous advantages compared with other methods. For one thing, you use adult cells to make iPS cells, so you no longer need embryos. Furthermore, the reprogrammed cells have the patient's DNA, so the body will be less likely to reject them.","In summary, XCR followed by X chromosome loss in female iPSCs explains the sex-specific DNA methylation events seen in our study. These observations might explain some of the changes described in a recent study of DNA methylation during reprogramming that did not examine the state of the X chromosome . We have not excluded the possibility that X chromosome loss takes place as a result of global DNA hypomethylation.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=33840716996&p=1pl&v=1&x=Mnhm9vKpmXnXvffrOX7_og
10.1038/s41598-017-03627-7,Medicine_318,He hopes the research will help lend scientific credence to the notion that touch can ease pain.,These findings can be explained by the fact that female participants experienced the real pain and their male partners only guessed the females' pain level.,"Goldstein did measure brainwave activity and plans to present those results in a future study. He hopes the research will help lend scientific credence to the notion that touch can ease pain. For now, he has some advice for partners in the delivery room: Be ready and available to hold your partner's hand.","Interestingly, the difference in pain between the conditions with and without touch was higher in females than in males, who estimated their partners' pain. These findings can be explained by the fact that female participants experienced the real pain and their male partners only guessed the females' pain level. It is thus possible that males did not realize the magnitude of the effectiveness of their touch and therefore their pain ratings did not decrease in the touch condition.","[2.0, 1.0, 5.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.3945/jn.113.188441,Medicine_319,"These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs.","The highest quintile for the TP was associated with decreased prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06), but neither of the dietary patterns was associated with prevalence of metabolic syndrome.","This association was found to be particularly strong for women. These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs. Dr. Shin discovered that consuming instant noodles two or more times a week was associated with cardiometabolic syndrome.","The highest MP quintile was associated with increased prevalence of abdominal obesity (OR: 1.41; 95% CI: 1.05, 1.90), LDL cholesterol $130 mg/dL (1.3 g/L) (OR: 1.57, 95% CI 1.26, 1.95), decreased prevalence of low HDL cholesterol (OR: 0.65; 95% CI: 0.53, 0.80), and high triglycerides [$150 mg/dL (1.5 g/L); OR: 0.73; 95% CI: 0.57, 0.93]. The highest quintile for the TP was associated with decreased prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06), but neither of the dietary patterns was associated with prevalence of metabolic syndrome. The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome (OR: 1.68; 95% CI: 1.10, 2.55) in women but not in men (OR: 0.93; 95% CI: 0.58, 1.49; P-interaction = 0.04).","[3.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.8,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.3945/jn.113.188441,Medicine_32,Women who ate a cup of them more than twice a week saw a 68% jump in cardiometabolic syndrome.,"The highest quintile for the TP was associated with decreased prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06), but neither of the dietary patterns was associated with prevalence of metabolic syndrome.","When instant noodles were thrown in the mix, researchers saw trouble. Women who ate a cup of them more than twice a week saw a 68% jump in cardiometabolic syndrome. It didn't matter what else they ate.","The highest MP quintile was associated with increased prevalence of abdominal obesity (OR: 1.41; 95% CI: 1.05, 1.90), LDL cholesterol $130 mg/dL (1.3 g/L) (OR: 1.57, 95% CI 1.26, 1.95), decreased prevalence of low HDL cholesterol (OR: 0.65; 95% CI: 0.53, 0.80), and high triglycerides [$150 mg/dL (1.5 g/L); OR: 0.73; 95% CI: 0.57, 0.93]. The highest quintile for the TP was associated with decreased prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06), but neither of the dietary patterns was associated with prevalence of metabolic syndrome. The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome (OR: 1.68; 95% CI: 1.10, 2.55) in women but not in men (OR: 0.93; 95% CI: 0.58, 1.49; P-interaction = 0.04).","[2.0, 1.0, 2.0, 1.0, 2.0]",Medicine,train,1.6,news,http://www.newser.com/story/192784/new-heart-disease-culprit-ramen.html
10.1016/j.bodyim.2016.09.005,Medicine_320,The researchers suggested parents should emphasize and discuss what entails having a healthy body with their little girls so that they can develop good body image concepts.,"Continued exposure to Barbie in early childhood may lead girls to not only adopt a thin ideal but also, in combination with a variety of other thin-ideal transmitters, may prime them to more readily accept future thin-ideal promoting messages.",This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better. The researchers suggested parents should emphasize and discuss what entails having a healthy body with their little girls so that they can develop good body image concepts. Mattel isn't buying the study's claims though.,"However, it is still possible that different types of exposure could have differential cumulative impact over time, which would only become apparent in a longitudinal study. Continued exposure to Barbie in early childhood may lead girls to not only adopt a thin ideal but also, in combination with a variety of other thin-ideal transmitters, may prime them to more readily accept future thin-ideal promoting messages. Future research is necessary to establish this link.","[2.0, 4.0, 3.0, 4.0, 2.0]",Medicine,train,3.0,news,http://www.parentherald.com/articles/97873/20170130/barbie-dolls-harm-little-girls-body-image-experts-advise-parents.htm
10.1016/j.neuron.2017.06.028,Medicine_321,"We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","We found that Bcan knockdown mice displayed the same short-term memory deficit exhibited by Bcan mutant mice , demonstrating that normal levels of BCAN specifically in PV+ cells are required for short-term memory.","These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories. When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London. We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","Interestingly, the discrimination index was higher in Bcan À/À mice than in controls (Figure 8M) , suggesting potentially enhanced long-term memory in absence of BCAN. We found that Bcan knockdown mice displayed the same short-term memory deficit exhibited by Bcan mutant mice , demonstrating that normal levels of BCAN specifically in PV+ cells are required for short-term memory. Altogether, these results demonstrate that BCAN regulates plasticity-dependent events that are essential for learning and memory.","[2.0, 1.0, 1.0]",Medicine,train,1.3333333333333333,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1016/j.neuron.2014.05.028,Medicine_322,"""The Tac2 gene is robustly activated after fear learning and belongs to a pathway that can be specifically blocked with a drug,"" Ressler says.",More studies about this topic would be desirable to further understand the mechanisms of the Tac2/ NkB/Nk3R pathway.,"The Tac2 gene was turned on more strongly during fear learning in mice that were previously exposed to a model of traumatic stress. ""The Tac2 gene is robustly activated after fear learning and belongs to a pathway that can be specifically blocked with a drug,"" Ressler says. ""It was interesting that Tac2 is highly expressed in one particular part of the amygdala, but with low or no expression in other brain areas related to the formation of fear memories.","To the best of our knowledge, this is the first evidence that a neuronal population specifically highly expressed in the CeM, Tac2 and its product NkB peptide, are required for the modulation of fear memory consolidation affecting neither unconditioned fear nor anxiety-like behavior. More studies about this topic would be desirable to further understand the mechanisms of the Tac2/ NkB/Nk3R pathway. Our findings also suggest that CeA-Tac2 lentiviral overexpression enhances fear memory consolidation but Nk3R antagonism prevents it.","[2.0, 2.0, 2.0, 2.0, 5.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jpeds.2017.10.028,Medicine_323,Punishment like spanking doesn't improve a child's behavior over the long-term.,"Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence.",My preference is to encourage positive behavioral management and decrease the use of punishment. Punishment like spanking doesn't improve a child's behavior over the long-term. Keep in mind that these strategies are useful for some children.,"Notably, this latter finding refers only to acts of violence and not frequency or severity, which is important, given research showing that female subjects may suffer more long-term negative physical and psychosocial consequences of teen dating violence. Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence. Finally, corporal punishment was associated with future physical perpetration of dating violence, even after controlling for demographic variables (ie, sex, ethnicity, age, parental education), as well as a history of childhood physical abuse.","[1.0, 1.0, 1.0, 3.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=32818256385&p=1pl&v=1&x=0ZAEkx105k29I5f3n6_nlQ
10.1038/s41467-019-09863-x,Medicine_324,"""Positive tipping points could be you rebuild in the aftermath of these disasters in a way that's more sustainable and resilient,"" he noted.",The scenarios extend out to 2300 to capture the effects of multiple slow physical processes including the PCF and the loss of the winter sea ice under high emissions pathways.,"Kopp pointed to the risk of socio-economic tipping points--changes in a society's ability to respond to or recover from repeated exposure to increasingly extreme weather or other severe climate-related events, such as hurricanes, wildfires or floods. ""Positive tipping points could be you rebuild in the aftermath of these disasters in a way that's more sustainable and resilient,"" he noted. Jina added that not all socio-economic tipping points may necessarily be triggered by sudden events like extreme weather.","We also introduce an intermediate 2.5°C target, which requires more mitigation than is proposed by the NDCs, and an NDCs Partial scenario with a persistent under-delivery on pledges consistent with an estimated long-term effect of the US's withdrawal from the Paris Agreement. The scenarios extend out to 2300 to capture the effects of multiple slow physical processes including the PCF and the loss of the winter sea ice under high emissions pathways. While very long horizons like this may appear irrelevant from the point of view of the actual socio-economic processes, the well-established technological, demographic and resource constraints 23 imply that the range of scenarios is still plausible beyond the 21st century 24 .","[3.0, 3.0, 1.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1111/all.13333,Medicine_326,"In addition, the researchers also said that while they didn't find the vaccine useful for prevention of hospitalization due to influenza community-acquired pneumonia it may be good for other outcomes.","Asthma patients seemed to have a higher risk of being admitted to the intensive care unit (ICU) or to have a more severe disease course when hospitalized for influenza, Severe disease was especially common in those developing pneumonia, but did not seem to be related to the severity of underlying asthma.","The study data also showed that while some of their results were in contradiction of some CDC results that was felt to be because the study only looked at a specific group while CDC looks at data from all groups. In addition, the researchers also said that while they didn't find the vaccine useful for prevention of hospitalization due to influenza community-acquired pneumonia it may be good for other outcomes. The researchers also found it did have supporting evidence that vaccine effectiveness varies substantially from year to year and that results from studies may not estimate true effectiveness either.","Interestingly, influenza-related hospitalization costs in children with asthma may be lower than in children with other chronic conditions and were very close to costs in children without comorbidity. Asthma patients seemed to have a higher risk of being admitted to the intensive care unit (ICU) or to have a more severe disease course when hospitalized for influenza, Severe disease was especially common in those developing pneumonia, but did not seem to be related to the severity of underlying asthma. In a multivariate analysis of H1N1 pediatric patients, asthma was associated with increased mortality in ICU-admitted children and adolescents (OR 1.34, P = .05).","[3.0, 1.0, 3.0, 2.0, 2.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=37849057616&p=1pl&v=1&x=xt4Zpy97jdfgJxOWwQtwhA
10.14814/phy2.13617,Medicine_327,"""In this study we found that these kids were extremely sensitive to light.""",The magnitude of the circadian response to light may differ in young children and therefore understanding the phase shifting effects of light in this age group is necessary to support age-based recommendations for evening light exposure.,"The study comes at a time when use of electronics is rapidly expanding among this age group and adds to a growing body of evidence suggesting that-because of structural differences in their eyes-children may be more vulnerable to the impact light has on sleep and the body clock. ""In this study we found that these kids were extremely sensitive to light."" Melatonin levels were 88 percent lower after bright light exposure.","Although this study was not designed to assess changes in circadian timing (phase shifts) in response to an experimental light stimulus, this represents an area of rich investigation. The magnitude of the circadian response to light may differ in young children and therefore understanding the phase shifting effects of light in this age group is necessary to support age-based recommendations for evening light exposure. Because the early childhood years are a sensitive and vulnerable window in human development (Center on the Developing Child, 2010), future research should investigate the role of evening light exposure in health and disease in early life.","[2.0, 3.0, 3.0, 4.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=33480456707&p=1pl&v=1&x=hN9hUXXld--gBVhWbWCNfA
10.1001/jama.2014.15690,Medicine_328,"Researchers also wrote that other benefits of aspirin including prevention of cancer, should be considered.","In the no aspirin group, the proportion of patients who started to take daily low-dose aspirin increased each year from 1.5% in year 1 to 9.8% in year 5.","""Japanese tend to have fewer heart attacks and more strokes, particularly more hemorrhagic strokes. In this study they had many more strokes than heart attacks, which is not something you'd see in a U.S. population,"" Gaziano said according to CBS News. Researchers also wrote that other benefits of aspirin including prevention of cancer, should be considered.","A total of 88.9% of patients reported that they were adherent in year 1; this value decreased to 76.0% in year 5 (eTable 1 in the Supplement). In the no aspirin group, the proportion of patients who started to take daily low-dose aspirin increased each year from 1.5% in year 1 to 9.8% in year 5. Most patients did not receive medicines (antiplatelet or anticoagulant agents) that had been, in principle, prohibited after enrollment; however, the proportion of patients receiving these prohibited medications increased over time in both the aspirin group (1.3% in year 1, 10.5% in year 5) and the no aspirin group (1.4% in year 1, 10.4% in year 5) (eTable 1 in the Supplement).","[2.0, 1.0, 2.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.counselheal.com/articles/13333/20141120/aspirin-cut-heart-problems-risk.htm
10.1186/gb-2013-14-7-r73,Medicine_329,The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers.,"Unlike vlinc_500 which is supported by the EST evidence, Vlinc_21 (~121 kb; panels C & D) is located within a totally un-annotated region of chromosome 1 with no spliced EST,~1.4 Mb from the closest UCSC gene annotation.","""Future research into the role and function of vlincRNAs holds promise for both highly targeted diagnostic tests and more precise cancer treatments. The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers. ""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics.""","Most of the RNAseq signal was in the intronic regions of these ESTs, consistent with the overall observation that majority of the ""dark matter"" RNA signal is intronic . Unlike vlinc_500 which is supported by the EST evidence, Vlinc_21 (~121 kb; panels C & D) is located within a totally un-annotated region of chromosome 1 with no spliced EST,~1.4 Mb from the closest UCSC gene annotation. RNAseq data shows density of informative reads normalized by 10M informative reads.","[2.0, 1.0, 1.0, 1.0, 2.0]",Medicine,train,1.4,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13059-018-1434-0,Medicine_33,Their results challenge the most extended paradigm of an exclusive role of positive selection in cancer evolution.,"In summary, the presented evidence supports a major role of negative selection in cancer evolution, which has been neglected in most studies, and ultimately challenges the current paradigm of an exclusive role of positive selection in cancer.","Their results challenge the most extended paradigm of an exclusive role of positive selection in cancer evolution. ""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer. ""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes.","Interestingly, AP-1 is essential for MHC complex I downregulation and immune escape upon HIV infection . In summary, the presented evidence supports a major role of negative selection in cancer evolution, which has been neglected in most studies, and ultimately challenges the current paradigm of an exclusive role of positive selection in cancer. These studies help to shed light upon the mechanisms underlying immune evasion and provide insights for improving cancer immunotherapies in the future.","[5.0, 4.0, 4.0, 4.0, 5.0]",Medicine,train,4.4,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1038/ncomms14514,Medicine_331,"Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","For colloidal NCs, the degree of compressive strain is dictated not just by the size, but also by surface faceting and the nature of surface ligands, which influence g: strongly passivating ligands can reduce the surface tension g, thereby relieving some degree of strain caused by small size.","This crystal structure is a result of internal strain in the clusters. It turns out with these clusters, every single cluster is exactly the same structure. Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","in equation (1)) increases. For colloidal NCs, the degree of compressive strain is dictated not just by the size, but also by surface faceting and the nature of surface ligands, which influence g: strongly passivating ligands can reduce the surface tension g, thereby relieving some degree of strain caused by small size. The higher compressive strain measured in the 2 nm Cu 2 Se clusters relative to the larger NCs is a result of the smaller crystallite size of the former along with some contribution from differences in ligand passivation: the clusters are capped with trioctylphosphine (TOP), whereas the 4 and 6 nm NCs are capped with octylamine.","[1.0, 1.0, 1.0, 2.0, 1.0]",Medicine,train,1.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uNVFlIGRBVk/
10.1038/ncomms14514,Medicine_332,"Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","Thus, the increase in tetrahedral site occupation measured by PXRD goes hand-in-hand with the decrease in the propensity of tetrahedral vacancy ordering seen in HRTEM.","This crystal structure is a result of internal strain in the clusters. It turns out with these clusters, every single cluster is exactly the same structure. Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","In fact, the best match for the experimental PXRD pattern of the 4 nm NCs, which shows a distinct {200} peak, is the anti-fluorite structure, wherein all or most 8c tetrahedral sites are occupied and there is little to no occupancy in 32f trigonal sites. Thus, the increase in tetrahedral site occupation measured by PXRD goes hand-in-hand with the decrease in the propensity of tetrahedral vacancy ordering seen in HRTEM. The experimental PXRD pattern for 2 nm clusters could not be reproduced using only 8c tetrahedral and 32f trigonal site occupation.","[1.0, 1.0, 1.0, 2.0, 1.0]",Medicine,train,1.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uNVFlIGRBVk/
10.1111/gcb.13526,Medicine_333,"""This rate is insufficient to fulfill the needs for global food security, where we need to produce 70-100% more food by 2050 to feed an estimated 9.7 billion people,"" said project co-lead Steve Long, Gutgsell Endowed Professor of Plant Biology and Crop Sciences at the Carl R. Woese Institute for Genomic Biology at Illinois.","The model therefore predicts that the additional two units of LAI above the model predicted optimum would not significantly contribute to net carbon gain, as photosynthesis roughly compensated for respiratory costs (Fig.","They attribute this boost in yield to increased photosynthesis, decreased respiration, and diversion of resources that would have been invested in more leaves than seeds. ""This rate is insufficient to fulfill the needs for global food security, where we need to produce 70-100% more food by 2050 to feed an estimated 9.7 billion people,"" said project co-lead Steve Long, Gutgsell Endowed Professor of Plant Biology and Crop Sciences at the Carl R. Woese Institute for Genomic Biology at Illinois. If we can increase the yield of soybeans, we can solve the problems of protein demand and food production at the same time.""","The difference in model-simulated NPP between observed LAI and model predicted optimum LAI was very small (% 3%) under both [CO 2 ] treatments. The model therefore predicts that the additional two units of LAI above the model predicted optimum would not significantly contribute to net carbon gain, as photosynthesis roughly compensated for respiratory costs (Fig. The predicted gains in yield were primarily due to decreased investment in leaves allowing predicted increase in seed production.","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.seeddaily.com/reports/Soybean_plants_with_fewer_leaves_yield_more_999.html
10.1016/j.cell.2013.08.004,Medicine_335,"These rhythms even influence hormone production, hunger, cell regeneration, and body temperature.","Significantly, the clock genes Per1 and Per2 also contain conserved CREs, which mediate their light induction .","""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and working as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules,"" said Duffield. These rhythms even influence hormone production, hunger, cell regeneration, and body temperature. The disruption of your normal circadian rhythm could possibly leave you susceptible to developing health complications later in life.","The promoters of many previously identified light-responsive genes in the SCN including Fos, Nr4a1, Egr1, Egr3 , the MAP kinase phosphatase Dusp1 , and miRNAs miR-132 and miR-217 all contain a highly conserved CRE. Significantly, the clock genes Per1 and Per2 also contain conserved CREs, which mediate their light induction . Elevated PER1 and PER2 adjust the molecular-feedback loop of the circadian oscillator to the light/dark (LD) cycle.","[1.0, 2.0, 1.0, 2.0, 2.0]",Medicine,train,1.6,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1377/hlthaff.2012.1030,Medicine_336,"In that group -- women with normal, full-term pregnancies and no prior C-section -- the rates ranged from 2.4 percent of births to 36.6 percent.","13 We identified this subset by excluding pregnancies with any of the following characteristics: preterm delivery (prior to thirty-seven weeks gestation, ICD-9 644.2, 644.20, 644.21), multiple gestation (ICD-9 651, 651.0X, 651.1X, 651.2X, 651.3X, 651.4X, 651.5X, 651.6X, 651.8X, 651.9X), fetal malpresentation (ICD-9 652.X, 660.0X), and prior cesarean delivery (ICD-9 654.20, 654.21, 654.23).","Among low-risk women, researchers found a 15-fold variation in C-section rates, according to Kozhimannil. In that group -- women with normal, full-term pregnancies and no prior C-section -- the rates ranged from 2.4 percent of births to 36.6 percent. Kozhimannil said they couldn't tell from the data what reasons doctors gave for ordering the C-sections.","32 Our final data set included 817,318 deliveries that occurred in 2009 at 593 different hospitals. 13 We identified this subset by excluding pregnancies with any of the following characteristics: preterm delivery (prior to thirty-seven weeks gestation, ICD-9 644.2, 644.20, 644.21), multiple gestation (ICD-9 651, 651.0X, 651.1X, 651.2X, 651.3X, 651.4X, 651.5X, 651.6X, 651.8X, 651.9X), fetal malpresentation (ICD-9 652.X, 660.0X), and prior cesarean delivery (ICD-9 654.20, 654.21, 654.23). Thirteen hospitals (2 percent of our sample) were missing data on bed size and were included in overall totals and plots but not in stratified estimates.","[4.0, 2.0, 1.0]",Medicine,train,2.0,news,http://www.startribune.com/lifestyle/health/195072291.html
10.1073/pnas.1408439111,Medicine_337,"They found that the two methods are comparable in accuracy when checked against actual survey-based census data, but estimates from mobile phone data can provide more timely information, down to the hours.",This study demonstrates how data collected by mobile phone network operators can costeffectively provide accurate and detailed maps of population distribution over national scales and any time period while guaranteeing phone users' privacy.,"During the holiday season, populations in cities dropped sharply, while tourist sites such as coastlines and Disneyland Paris boomed. They found that the two methods are comparable in accuracy when checked against actual survey-based census data, but estimates from mobile phone data can provide more timely information, down to the hours. To apply it in other countries, the team would need to adjust the model to account for diverse mobile phone usage patterns.","The global MP penetration Significance Knowing where people are is critical for accurate impact assessments and intervention planning, particularly those focused on population health, food security, climate change, conflicts, and natural disasters. This study demonstrates how data collected by mobile phone network operators can costeffectively provide accurate and detailed maps of population distribution over national scales and any time period while guaranteeing phone users' privacy. The methods outlined may be applied to estimate human population densities in lowincome countries where data on population distributions may be scarce, outdated, and unreliable, or to estimate temporal variations in population density.","[4.0, 4.0, 4.0]",Medicine,train,4.0,news,http://news.sciencemag.org/math/2014/10/taking-census-cellphones
10.1001/jamasurg.2018.0672,Medicine_34,"The researchers found that the inadequate and problematic FHL groups had a global score of SwQoR that indicated poor recovery (37.4 and 22.9, respectively).",The global score of SwQoR indicated poor recovery in both inadequate (37.2) and problematic (22.,"Of the 704 patients, 60.7, 31.7, and 7.7 percent reported sufficient, problematic, and inadequate FHL, respectively. The researchers found that the inadequate and problematic FHL groups had a global score of SwQoR that indicated poor recovery (37.4 and 22.9, respectively). The difference in the global score of SwQoR between inadequate and sufficient FHL (37.4 and 17.7) was statistically significant.","There were no statistical differences between the 3 groups in age, sex, type of anesthesia and surgery, or ASA classification ( Table 1) . The global score of SwQoR indicated poor recovery in both inadequate (37.2) and problematic (22. There were no differences between the groups in health care contacts ( Table 4) .","[5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,news,http://ct.moreover.com/?a=33900191633&p=1pl&v=1&x=U2NKEgQRLXmLRbYHpHEUVQ
10.1038/s41598-018-35253-2,Medicine_340,Further analysis allowed them to find the exact sources of the methane--microbiological activity on the glacier bed.,"Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig.","The highest concentrations of methane were at the point where the river emerges from beneath the glacier. Further analysis allowed them to find the exact sources of the methane--microbiological activity on the glacier bed. Researchers say that while the study only focuses on Solheimajokull and Katla, there are many other ice-covered active volcanoes that could produce methane in a similar way.","As the most enriched values exceed the geogenic range, the observed isotopic signatures cannot be explained by a mixture of biogenic and geogenic methane (Fig. Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig. S2 ), likely explains the isotopic fractionation trajectory away from the microbial end member signature.","[2.0, 4.0, 5.0, 4.0]",Medicine,train,3.75,news,http://ct.moreover.com/?a=37747037897&p=1pl&v=1&x=25zujygYqDoju4-7l9c6zQ
10.1080/10635150701775111,Medicine_341,"In all three cases, the data was limited, especially in the case of the ecological niche modeling.",We find that ecological niche modeling has considerable utility in recognizing closely related species in Phelsuma.,"He admits three specimens was not a lot, but ""the whole genome data of one passenger pigeon carries the information of the whole species."" In all three cases, the data was limited, especially in the case of the ecological niche modeling. Yet, Chih-Ming is confident.","nov. were found inhabiting a single plant, however we never found this species associated together with other Phelsuma species at the type locality. We find that ecological niche modeling has considerable utility in recognizing closely related species in Phelsuma. In both our empirical studies, these species complexes were found to include taxa that occupied divergent niche space.","[4.0, 2.0, 2.0, 2.0, 3.0]",Medicine,train,2.6,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1016/j.cell.2015.07.058,Medicine_342,"In cancer cells, MRN is already so preoccupied with responding to DNA breaks in cancer cells that an engineered virus could sneak in undetected.",This raises the intriguing possibility that the assembly of virus genomes in nuclear domains is sensed through the disruption of surrounding cellular chromatin.,"O'Shea says this may explain why people with conditions resulting in high levels of cellular DNA damage (e.g., cancer, chemotherapy, inflammation and aging) are more susceptible to viral infections. ""Our work implies that we may be able to engineer viruses that selectively kill cancer cells."" In cancer cells, MRN is already so preoccupied with responding to DNA breaks in cancer cells that an engineered virus could sneak in undetected.","(legend on next page) S1). This raises the intriguing possibility that the assembly of virus genomes in nuclear domains is sensed through the disruption of surrounding cellular chromatin. In contrast to cellular DNA breaks ( Figure 3C ) , phospho-ATM is not retained at E2A domains ( Figure 3D ) and diffuses throughout the nucleus where it phosphorylates global cellular DDR substrates.","[2.0, 2.0, 2.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1007/s10803-017-3154-9,Medicine_346,"""Our results underscore the importance of a multidisciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological and psychiatric, adaptive, sleep, and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services,"" Righi and coauthors write in the study published in the Journal of Autism and Developmental Disorders.","Overall, our findings emphasize the utility of thorough assessment and treatment of mood and sleep conditions, to decrease the likelihood of requiring psychiatric hospitalization.","The strongest risk factors--disrupted sleep, having a mood disorder, and living in a home with a single caregiver--are not necessarily associated with ASD. ""Our results underscore the importance of a multidisciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological and psychiatric, adaptive, sleep, and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services,"" Righi and coauthors write in the study published in the Journal of Autism and Developmental Disorders. By employing statistical analysis techniques, the researchers were able to isolate risk factors that were independently and significantly associated with the risk of hospitalization.","The results of the present study are in agreement with the literature linking sleep problems with an overall more severe psychiatric presentation, but also suggest that active sleep problems can be an indicator of significant behavioral crisis. Overall, our findings emphasize the utility of thorough assessment and treatment of mood and sleep conditions, to decrease the likelihood of requiring psychiatric hospitalization. There are aspects of the study design that should be considered when interpreting the findings.","[5.0, 4.0, 5.0]",Medicine,train,4.666666666666667,news,http://www.futurity.org/autism-asd-hospital-1448782/
10.1073/pnas.1414221111,Medicine_347,"In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours.","In addition, (+)-SJ733 met all other criteria for a clinical candidate, including high oral bioavailability, a high safety margin, and transmission blocking activity.","In this study, researchers determined that (+)-SJ733 uses a novel mechanism to kill the parasite by recruiting the immune system to eliminate malaria-infected red blood cells. In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours. After 48 hours the parasite was undetectable.","Although in vitro selection of pfatp4 mutants with (+)-SJ733 proceeded with moderate frequency, during in vivo selection of pbatp4 mutants, resistance emerged slowly and produced marginally resistant mutants with poor fitness. In addition, (+)-SJ733 met all other criteria for a clinical candidate, including high oral bioavailability, a high safety margin, and transmission blocking activity. These results demonstrate that targeting ATP4 has great potential to deliver useful drugs for malaria eradication.","[3.0, 5.0, 1.0, 3.0]",Medicine,train,3.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1038/s41467-018-04906-1,Medicine_348,"According to the research paper, the sensor developed by the team ""can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display,"" and at a resolution that satisfies FBI security standards.","Furthermore, the low R s of the AgNF-AgNW hybrid electrodes can drive this sensor array at 1 MHz reliably to handle typical noise from mobile devices or displays.","Getty Images

Forget fingerprint scanners tucked away on the back of your phone or beneath a home button -- your next smartphone is probably going to have a fingerprint sensor under the screen that measures your temperature, just to make sure you're a real human. According to the research paper, the sensor developed by the team ""can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display,"" and at a resolution that satisfies FBI security standards. Don't expect the new sensor to detect a fever through your finger just yet -- the temperature sensor is designed to detect human skin temperature to make sure you're not using a fake hand or artificial fingerprint to spoof security.","The sensing capability, in terms of capacitance variation (between a ridge and a valley) is up to 17 times better than that of an identical sensor structure using conventional ITO electrodes. Furthermore, the low R s of the AgNF-AgNW hybrid electrodes can drive this sensor array at 1 MHz reliably to handle typical noise from mobile devices or displays. The demonstration of its integration with pressure and temperature sensors, all of which had transparent and flexible forms, indicates the potential for replacement of the activation button on smartphones.","[3.0, 2.0, 2.0]",Medicine,train,2.333333333333333,news,http://ct.moreover.com/?a=34461950539&p=1pl&v=1&x=XLGqlDf_Oo7GWj0vCJKGfw
10.1098/rspb.2018.0761,Medicine_349,"They showed bumblebee queens were far less active and six times more likely to die during sustained exposure (37 days) to the pesticide, which could be somewhat mitigated by a shorter exposure of 17 days.","We found that queens exhibited increased mortality and dramatically reduced activity levels when exposed to imidacloprid, as well as delayed nest initiation and lower brood numbers in the nest, but partially recovered from these effects when they only received early, temporary exposure.","Led by Hollis Woodard, an assistant professor of entomology, the team found that exposure to a widely used insecticide and a poor diet negatively impacted bumblebee queens' health and work, which could have dramatic consequences on an already dwindling pollinator group. They showed bumblebee queens were far less active and six times more likely to die during sustained exposure (37 days) to the pesticide, which could be somewhat mitigated by a shorter exposure of 17 days. The surviving exposed bees also produced only a third of the eggs and a fourth of the larvae of untreated queens.","Nest initiation and survival are thus key drivers of both bumblebee pollination services and population dynamics. We found that queens exhibited increased mortality and dramatically reduced activity levels when exposed to imidacloprid, as well as delayed nest initiation and lower brood numbers in the nest, but partially recovered from these effects when they only received early, temporary exposure. The effects of pollen diet on individual queen-and colony-level responses were overshadowed by effects of the insecticide, although a monofloral pollen diet alone was sufficient to negatively impact brood production.","[4.0, 5.0, 4.0, 3.0]",Medicine,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ea2TPwN3kfM/
10.1016/j.cell.2015.07.058,Medicine_35,This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability.,This provides an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability.,"MRN starts a domino effect, activating histones on surrounding chromosomes, which summons a cascade of additional proteins, resulting in a cell-wide, all-hands-on-deck alarm to help mend the DNA. This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability. Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea.","Thus, gH2AX foci discriminate ''self'' and ''non-self'' genomes and determine whether a localized anti-viral or global ATM response is appropriate. This provides an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability. In Brief gH2AX foci discriminate ''self'' and ''nonself'' genomes and determine whether a localized anti-viral or global ATM response is appropriate, providing an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability.","[5.0, 5.0, 4.0, 5.0]",Medicine,train,4.75,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1016/j.jalz.2018.06.2856,Medicine_350,They say their findings could lead to new ways to identify people at high risk for Alzheimer's.,"In contrast, a smaller population-based cohort of 812 in three French cities showed substantially increased dementia risk (odds ratio 3.9, [1.5, 10.4]) in participants with glaucoma during 3 years, but only analyzed 2436 person-years, roughly 1/6 of our follow-up .","They say their findings could lead to new ways to identify people at high risk for Alzheimer's. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss,"" Lee explained in a university news release. Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said.","Similarly, a retrospective study using 5% of Medicare claims data revealed no increased AD risk in people with glaucoma (n 5 63,235) compared with propensity score-matched people without glaucoma during 14 years of follow-up (HR 0.91, [0.88, 0.93]) . In contrast, a smaller population-based cohort of 812 in three French cities showed substantially increased dementia risk (odds ratio 3.9, [1.5, 10.4]) in participants with glaucoma during 3 years, but only analyzed 2436 person-years, roughly 1/6 of our follow-up . The Rotterdam Study followed 1438 dementia-free participants aged 75 years for an average of 25 months and found increased AD risk in those with advanced AMD (HR 2.1, [1.1, 4.3] ), but this became insignificant with smoking and atherosclerosis included in the model .","[4.0, 3.0, 4.0]",Medicine,train,3.6666666666666665,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1002/cncr.30428,Medicine_351,"Specifically, each unit increase in mastery was associated with a 16.1% reduction in the risk of patient death (95% CI, 0.771-0.913; P <.001).","When known covariates were used in multivariable models (adjusting for the patient's functional status [KPS], postsurgical treatment, type of surgery, and age), only the association between caregiver mastery and patient survival remained statistically significant.","After controlling for confounding factors, researchers found that caregiver mastery was independently associated with patient survival. Specifically, each unit increase in mastery was associated with a 16.1% reduction in the risk of patient death (95% CI, 0.771-0.913; P <.001). Further studies are needed to validate these findings.","Caregiver mastery also was found to be associated with patient survival, with a 14% reduction in the probability of dying sooner (hazard) with each unit increase in mastery (95% CI, 0.79-0.93, based on 88 cases). When known covariates were used in multivariable models (adjusting for the patient's functional status [KPS], postsurgical treatment, type of surgery, and age), only the association between caregiver mastery and patient survival remained statistically significant. Each unit increase in caregiver mastery was associated with a 16.1% decreased hazard of patient death (95% CI, 0.77-0.91, based on 88 cases).","[3.0, 2.0, 4.0, 3.0]",Medicine,train,3.0,news,http://www.oncologynurseadvisor.com/caregiver-characteristics-and-glioblastoma-multiforme-outcomes/article/569022/
10.1007/s13524-014-0324-7,Medicine_352,"If you're part of a heterosexual couple and you're relocating for work, odds are it's the man's career that's driving the move.","For example, using mobility rates, found that veterinarians, head cooks, and cashiers relocate often, but intuitively these jobs would be relatively robust to spousal relocations.","If you're part of a heterosexual couple and you're relocating for work, odds are it's the man's career that's driving the move. This disparity in the geographic requirements of male- and female-heavy industry, says Benson in his study, suggests that it might be the demands of the job, rather than an inherent male bias in married couples' power dynamics, that's behind the uneven treatment. ""The tendency for men to move more often than women is completely explained by the types of jobs they enter, not that they are men or women,"" said Benson to the Post's Dina ElBoghdady.","It is not clear from the incidence of work relocations alone whether the geography of the relocating worker was constrained. For example, using mobility rates, found that veterinarians, head cooks, and cashiers relocate often, but intuitively these jobs would be relatively robust to spousal relocations. Third, an advantage of using the clustering index is that the census does not report why individuals relocate for work.","[2.0, 2.0, 1.0, 2.0]",Medicine,train,1.75,news,http://www.smithsonianmag.com/smart-news/why-do-families-move-mens-not-womens-careers-180953490/
10.1210/jc.2013-2350,Medicine_355,"Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants.","Of note, the left ventricular mass index was linearly related to the degree of IR .","Women who had PCOS also had a higher rate of endometrial cancer, or cancer of the lining of the uterus. Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants. A PCOS diagnosis also was associated with a higher risk of late onset diabetes, high blood pressure, heart disease, asthma and musculoskeletal disorders.","Echocardiography revealed both anatomic and functional differences between women with PCOS and controls including an increased left atrial size, increased left ventricular mass index, lower left ventricular ejection fraction , and diastolic dysfunction . Of note, the left ventricular mass index was linearly related to the degree of IR . The Nurses' Health Study noted an adjusted RR of 1.53 (95% CI, 1.24 -1.90) for coronary heart disease in women with a history of irregular menstrual cycles .","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1210/jc.2013-2350,Medicine_356,"""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening.""",The relative success of two drugs that modulate estrogen action to achieve pregnancy further underscores this class of drugs as first-line treatment when compared with insulin sensitizers.,"""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening."" In the CPG, The Endocrine Society recommends that a diagnosis be made if adult women have two of the three cardinal features of PCOS (diagnostic criteria supported by the NIH panel):* Excess production of male hormones called androgens. Other recommendations from the CPG include:

* Because women with PCOS face an increased risk of pregnancy complications such as gestational diabetes, preterm delivery and preeclampsia that can be exacerbated by obesity, women should have their body mass index, blood pressure and oral glucose tolerance assessed prior to conceiving;

* Following diagnosis, women with PCOS should be examined for skin and hair complications including excess hair growth and acne;

* Although women with PCOS have some of the same risk factors associated with the development of endometrial cancer, they should not routinely undergo ultrasound screening for endometrial thickness;

* To gauge metabolic risk, adolescents and adult women with PCOS should be screened for increased obesity using body mass index and waist circumference measurements;

* Clinicians should give adolescents and adult women with PCOS an oral glucose tolerance test to check for type 2 diabetes or impaired glucose tolerance because they are at increased risk of these conditions; and

* Initial treatment of type 2 diabetes or impaired glucose tolerance in women with PCOS should be diet and exercise, with metformin as a second-line therapy.","Although concerns about the relative teratogenicity of letrozole compared to clomiphene remain, this trial and other publications are reassuring . The relative success of two drugs that modulate estrogen action to achieve pregnancy further underscores this class of drugs as first-line treatment when compared with insulin sensitizers. Metformin may have some use as an adjuvant agent for infertility in select women with PCOS, although it is likely to be more effective in obese women than nonobese women .","[1.0, 2.0, 1.0]",Medicine,train,1.3333333333333333,news,http://www.newswise.com/articles/experts-clarify-conflicting-criteria-for-diagnosing-polycystic-ovary-syndrome
10.1016/j.immuni.2019.05.007,Medicine_357,"We may be closer than ever to ending those miserable days of vomiting, diarrhea and harsh fever after eating contaminated food or shaking the wrong person's hand.",Increased understanding of which capsid epitopes should be targeted to protect against different genotypes and of the impact of pre-exposure history on the elicitation of protective immunity after vaccination are important considerations in vaccine design and efficacy .,"We may be closer than ever to ending those miserable days of vomiting, diarrhea and harsh fever after eating contaminated food or shaking the wrong person's hand. A research discovery at UNC-Chapel Hill could help tackle stomach flu. Local news has never been more important To support vital, local reporting like the coronavirus coverage, please sign up for a digital subscription to charlotteobserver.com #readlocal

Norovirus causes more than 200,000 deaths, mostly young children and elderly, around the world each year, according to the Centers for Disease Control and Prevention.","One antibody recognizes a neutralizing epitope conserved across three decades of pandemic strains and neutralizes virus in vitro, demonstrating that vaccination can elicit pandemicstrain neutralizing antibody responses in some individuals. Increased understanding of which capsid epitopes should be targeted to protect against different genotypes and of the impact of pre-exposure history on the elicitation of protective immunity after vaccination are important considerations in vaccine design and efficacy . Multivalent VLP immunization broadens the breadth of blockade antibodies produced after immunization of mice and humans .","[2.0, 4.0, 1.0, 2.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39573303215&p=1pl&v=1&x=LZ9cWPbe63hLu_eeKZOP_g
10.1126/science.1252496,Medicine_358,"""The fact that the two largest fluffy particles have crystalline material-a magnesium-iron-silicate mineral called olivine-may imply that these are particles that came from the disks around other stars and were modified in the interstellar medium,"" said Andrew Westphal, one of the researchers, in a news release.",This value is in good agreement with the preflight estimates of Landgraf et al.,"For example, the small ones are much more different than the larger ones, and may have had different histories. ""The fact that the two largest fluffy particles have crystalline material-a magnesium-iron-silicate mineral called olivine-may imply that these are particles that came from the disks around other stars and were modified in the interstellar medium,"" said Andrew Westphal, one of the researchers, in a news release. ""We seem to be getting our first glimpse of the surprising diversity of interstellar dust particles, which is impossible to explore through astronomical observations alone.""","The observed impact density of nonterrestrial materials on the foils is 0.8 cm −2 , and thus the fraction of impacts of interplanetary origin is estimated to be 0.17/0.8 = 0.2. This value is in good agreement with the preflight estimates of Landgraf et al. With the conservative assumption that all of the interplanetary dust is <2 mm, this equates to 100 small particles (80 interstellar and 20 interplanetary), of which 20% should be interplanetary.","[3.0, 3.0, 2.0, 1.0]",Medicine,train,2.25,news,http://www.scienceworldreport.com/articles/16631/20140815/stardust-spacecraft-captured-tiny-dust-grains-interstellar-space.htm
10.1186/s12916-017-0986-2,Medicine_36,"""This study highlights how common postoperative complications are among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults who may be at risk.""",Our study had a number of strengths.,"""Older adults are a diverse group of patients whose risk of postoperative complications is not solely defined by their age, comorbidities or the type of surgical procedure they receive,"" said Dr. Watt. ""This study highlights how common postoperative complications are among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults who may be at risk."" The review did not examine why frailty was associated with negative outcomes following surgery, but the authors hypothesize that frailty and not older age was associated with postoperative complications because frailty represents a patient's biological age as opposed to their chronological age.","This is a limitation that is inherent in the prognosis literature that we hope will be overcome in the future by improved quality of reporting. Our study had a number of strengths. The hypothesis-generating nature of this study allowed for the identification of prognostic factors that are potentially modifiable in the preoperative setting, which could lead to better surgical outcomes for older adults undergoing elective surgery.","[1.0, 1.0, 4.0, 1.0]",Medicine,train,4.0,news,http://healthmedicinet.com/news/age-is-not-a-risk-factor-for-complications-after-surgery-among-older-patients/
10.1073/pnas.1511220112,Medicine_360,"""The mix of ape and human features observed in A. afarensis' shoulder support the notion that, while bipedal, the species engaged in tree climbing and wielded stone tools.","Regardless, if the LCA was more Pan-like, then early hominins reevolved a Gorilla-like spine/glenoid angle, but if more Gorilla-like, then the more cranial angle in Pan is a later evolutionary event convergent on some hylobatids, perhaps due to increased arborealism relative to the ancestral African ape.","This positioning is consistent with evidence for increasingly sophisticated tool use in Australopithecus. ""The mix of ape and human features observed in A. afarensis' shoulder support the notion that, while bipedal, the species engaged in tree climbing and wielded stone tools. ""These changes in the shoulder, which were probably initially driven by the use of tools well back into human evolution, also made us great throwers,"" Roach said.","Body size is also strongly linked to social structure; thus, any reconstruction invoking a Gorilla-like body size would also have additional implications beyond the skeletal phenotype (e.g., multimale, multifemale in Pan troglodytes vs. a single male, multifemale group in Gorilla) . Regardless, if the LCA was more Pan-like, then early hominins reevolved a Gorilla-like spine/glenoid angle, but if more Gorilla-like, then the more cranial angle in Pan is a later evolutionary event convergent on some hylobatids, perhaps due to increased arborealism relative to the ancestral African ape. Absent fossil representatives of either Pan or Gorilla lineages, it is not possible to discriminate these alternatives.","[1.0, 4.0]",Medicine,train,3.0,news,http://www.technology.org/2015/09/09/shouldering-burden-evolution/
10.1016/j.ijnurstu.2014.02.007,Medicine_363,"That report showed wide variation in staffing levels across UK ICUs, and wide variation in patients' survival chances, but was unable to show a relationship between higher numbers of staff and better patient outcomes.","They found no association between medical staffing ratios and either ICU or hospital mortality but at the highest ratio (1:15), length of stay in the ICU was significantly higher.","New modelling techniques, and a different approach to the data, have enabled the researchers to reach different conclusions from those reported by the Audit Commission in their 1999 report, 'Critical to Success'. That report showed wide variation in staffing levels across UK ICUs, and wide variation in patients' survival chances, but was unable to show a relationship between higher numbers of staff and better patient outcomes. Although the dataset is now 'old', it is the best currently available on staffing and outcomes in ICU.","However, they did not control for the number of nurses or bed occupancy, both of which might mediate the relationship between medical staff and patient outcomes. They found no association between medical staffing ratios and either ICU or hospital mortality but at the highest ratio (1:15), length of stay in the ICU was significantly higher. Although failure to rescue has previously been associated with the number of nurses, this study shows that the number of medical staff is also important.","[4.0, 3.0, 4.0, 4.0, 2.0]",Medicine,train,3.4,news,http://www.healthcanal.com/public-health-safety/49249-low-icu-staffing-levels-affect-patient-survival.html
10.1016/j.jpeds.2009.01.015,Medicine_364,"In other words, among overweight and obese kids, a doubling of sodium intake was associated with a 3 percent increase in systolic blood pressure.","At the same time, the P value for trend in the sugar-sweetened beverages and systolic blood pressure association is very close to the conventional threshold for statistical significance so it is possible that this is a false positive association due to chance.","(The two groups' average diastolic pressures, the bottom number in the ratio, were the same.) In other words, among overweight and obese kids, a doubling of sodium intake was associated with a 3 percent increase in systolic blood pressure. An average systolic blood-pressure difference of 3 percent could, however, have consequences for overall public health.","This misclassification bias may also diminish the observed effect size of the sugar-sweetened beverage consumption and systolic blood pressure association. At the same time, the P value for trend in the sugar-sweetened beverages and systolic blood pressure association is very close to the conventional threshold for statistical significance so it is possible that this is a false positive association due to chance. The effect of family history of gout and hypertension could affect serum uric acid and systolic blood pressure through several potential pathways.","[1.0, 3.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.scientificamerican.com/article.cfm?id=what-science-on-hypertension-really-shows
10.1093/gerona/glt162,Medicine_365,"So, the ""work longer"" strategy might be physically possible for large numbers of older people.",Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in health trajectories across the life span.,"Based on this data, it's probably safe to say that roughly eight out of 10 people in their late 60s are healthy enough to work in some capacity, roughly three-fourths of people in their 70s could work and maybe half of those in their early 80s could work. So, the ""work longer"" strategy might be physically possible for large numbers of older people. My suspicion is that many people who respond to surveys by saying they expect to work until age 70 or beyond haven't really thought through the implications of that decision.","Instead, different people appear to be experiencing widely different health trajectories with widely different health outcomes at the same ages. Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in health trajectories across the life span. These findings have important implications for five policy issues surrounding aging.","[3.0, 1.0, 4.0, 1.0]",Medicine,train,1.0,news,http://www.cbsnews.com/news/how-long-could-you-delay-retirement/
10.1126/science.1252496,Medicine_366,"While the samples are suspected to be from beyond the solar system, he says, potential confirmation of their origin must come from subsequent tests that will ultimately destroy some of the particles.","The residues of the particles captured in the Al foil appear to be amorphous, but whether this is an original feature or an effect of hypervelocity capture alteration is unclear.","All analysis was non-destructive, meaning that it preserved the structural and chemical properties of the particles. While the samples are suspected to be from beyond the solar system, he says, potential confirmation of their origin must come from subsequent tests that will ultimately destroy some of the particles. ""These particles are so precious.","This hypothesis may be testable by a future measurement of the isotopic composition of oxygen. The residues of the particles captured in the Al foil appear to be amorphous, but whether this is an original feature or an effect of hypervelocity capture alteration is unclear. Three of the four craters contain sulfides, whereas Orion contains only minor amounts of sulfur and Hylabrook has no appreciable sulfur content.","[3.0, 2.0, 2.0, 1.0, 5.0]",Medicine,train,2.0,news,http://www.nanowerk.com/news2/space/newsid=37140.php
10.1016/j.neuron.2018.12.026,Medicine_367,Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.,"The results above suggest that despite substantial loss of inhibition, L2/3 spike rate may be relatively unchanged or even reduced in vivo.","Note: material may have been edited for length and content. For further information, please contact the cited source. Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.","The only exception was a non-significant trend toward reduced, not increased, PSP amplitude in Fmr1 À/y mice near spike threshold ( Figures 4E and 4F ). The results above suggest that despite substantial loss of inhibition, L2/3 spike rate may be relatively unchanged or even reduced in vivo. Spontaneous spiking of L2/3 FS units was significantly reduced in Fmr1 À/y mice and showed non-significant trends toward reduction in other ASD mutants ( Figure 5D ) (bootstrapped median firing rate [Hz]: Fmr1 +/y 0.76, Fmr1 À/y 0.40, p = 0.04; Cntnap2 +/+ 0.99, Cntnap2 À/À 0.77, p = 0.83; 16p11.2 +/+ 1.20, 16p11.2 del/+ 0.50, p = 0.08, permutation test).","[2.0, 2.0, 1.0]",Medicine,train,1.6666666666666667,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1038/s41591-018-0091-x,Medicine_368,"The results revealed that two particular enhancers, regulating SLC9A3R1 and Yin Yang 1 genes, are activated at specific stages when they might help cancer cells grow and evade treatment.","YY1positive cells appear to dominate both primary and metastatic lesions in luminal patients, suggesting that this might remain important even after ET ( Fig.","The cancer might have changed significantly in this time, and would respond to different treatments. The results revealed that two particular enhancers, regulating SLC9A3R1 and Yin Yang 1 genes, are activated at specific stages when they might help cancer cells grow and evade treatment. In particular Yin Yang1 was found to switch on SLC9A3R1, which helped tumours grow.","YY1 contributes to endocrine resistance in luminal BC. YY1positive cells appear to dominate both primary and metastatic lesions in luminal patients, suggesting that this might remain important even after ET ( Fig. Interestingly, LTED cells have an expanded repertoire of ERα binding compared to MCF7, fuelled by endogenous ligands 10 .","[2.0, 2.0, 3.0, 4.0]",Medicine,train,2.75,news,http://ct.moreover.com/?a=34627030168&p=1pl&v=1&x=hF9k2ZTU-XUiToM72b9JHA
10.1073/pnas.1408439111,Medicine_369,"When this information is repeated multiple times, over millions of users, we can extract a detailed picture of population density and how it changes over time in a given area.""","Applying the approach to countries such as the DRC, where reliable training data may not be available, requires some adjustments and assumptions, particularly regarding the relation between the MP user density and the population density, through estimates for the parameters α and β.","However, anonymous phone data can be examined regularly to map daily, weekly or monthly changes across an entire country, at less cost and with greater flexibility. When this information is repeated multiple times, over millions of users, we can extract a detailed picture of population density and how it changes over time in a given area."" These maps were found to be as accurate as traditional census-based maps, which the researchers generated from data from the National Institute of Statistics and Economic Studies of France and the National Institute of Statistics of Portugal.","Even if at present the most remote and isolated populations may not have reception in some low-income countries, possibly affecting the ability to produce a comprehensive countrywide map, network coverage continues to grow at a rapid rate everywhere. Applying the approach to countries such as the DRC, where reliable training data may not be available, requires some adjustments and assumptions, particularly regarding the relation between the MP user density and the population density, through estimates for the parameters α and β. This relation indeed may vary among and within countries according to the penetration rate of the network operator and phone use behaviors.","[2.0, 4.0, 1.0, 3.0]",Medicine,train,2.5,news,http://www.sciencedaily.com/releases/2014/10/141028082456.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jama.2018.20578,Medicine_37,The use of aspirin in patients without cardiovascular disease was associated with increased risk of major bleeding.,The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude.,"In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not associated with a reduction in all-cause mortality. The use of aspirin in patients without cardiovascular disease was associated with increased risk of major bleeding. In this systematic review and meta-analysis including more than 160,000 patients, aspirin was associated with a reduction in the likelihood of adverse cardiovascular outcomes, such as cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke, though there was no reduction in all-cause mortality.","6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64% (5% CI, 0.35%-0.7%) for major bleeding. The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude. Aspirin use was not associated with a reduction in cardiovascular mortality, and deaths due to bleeding were rare.","[2.0, 4.0, 3.0, 2.0, 3.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=38328030969&p=1pl&v=1&x=7e7iZH1GB8Gg-5kdEyEhYQ
10.3945/an.111.000513,Medicine_370,"Eating apples can increase the production of saliva in the mouth, eliminating bacteria and food particles.",AP might be protective because of their antioxidant potential and phytochemical content.,"Better oral health

Alkaline foods can help promote acidic balance, and apples just happen to be a great alkaline fruit. Eating apples can increase the production of saliva in the mouth, eliminating bacteria and food particles. This can help in reducing the risk of bad breath.","If these findings are applicable to the in vivo situation, altered intestinal lipid secretion might account for the lipid-lowering effect of AP observed in some studies and suggest one possible mechanism for reduced risk of cardiovascular disease. AP might be protective because of their antioxidant potential and phytochemical content. Diagnosed asthma, on the basis of self-reported data using validated questionnaires, was present in 3.1% of the cohort.","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=35001604984&p=1pl&v=1&x=gj9dPxhyqwLYLECDqTxsew
10.1038/s41598-018-35253-2,Medicine_371,"This demonstrates the methane must be sourced from beneath the glacier,"" Dr Wynn explains.","Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig.","""The highest concentrations were found at the point where the river emerges from underneath the glacier and enters the lake. This demonstrates the methane must be sourced from beneath the glacier,"" Dr Wynn explains. But there is still a connection with the volcano.","As the most enriched values exceed the geogenic range, the observed isotopic signatures cannot be explained by a mixture of biogenic and geogenic methane (Fig. Extensive potential for methanotrophic activity, as evidenced through the incubation of sediments under oxidizing conditions (see Supplementary Fig. S2 ), likely explains the isotopic fractionation trajectory away from the microbial end member signature.","[2.0, 1.0, 1.0, 2.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=37746306455&p=1pl&v=1&x=Jqs7WivP4DGVbjXdDvLl4g
10.1136/injuryprev-2013-040923,Medicine_372,"""While pedestrian deaths are more common in many parts of Africa, motorcycle and bicycle deaths occur more frequently in southeast Asia."," 4 Baker et al showed that infectious diseases made up only 1% of traveller deaths, despite being a prominent focus for travel clinics and government agencies working to reduce risk abroad.","""While pedestrian deaths are more common in many parts of Africa, motorcycle and bicycle deaths occur more frequently in southeast Asia. One limitation of the study, which the authors acknowledge, is that we still do not know the characteristics of people who travel to different countries."" Out of all the countries deemed unsafe for travel, Thailand ranked in first among the most traffic-related deaths with 16.5 deaths per one million visits, Reuters reported.","However, this information cannot be used to effectively communicate risk information because it does not account for the number of outbound trips to the countries of interest.  4 Baker et al showed that infectious diseases made up only 1% of traveller deaths, despite being a prominent focus for travel clinics and government agencies working to reduce risk abroad. For US citizens, injuries accounted for 1 deaths abroad from 004 to 00, and among these, road traffic fatalities were shown to account for nearly a third of all injury deaths.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.medicaldaily.com/road-crashes-1-killer-americans-abroad-more-us-citizens-died-car-or-motorcycle-accidents-terrorist
10.1016/j.cmet.2015.02.003,Medicine_373,"Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal molecules than those that grew in a culture medium without salt.",Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation.,"Titze and his colleagues realized that immune cells arriving in wounded skin to fight infections were entering a salty microenvironment. Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal molecules than those that grew in a culture medium without salt. After 24 hours, the E. coli load in macrophages exposed to high sodium chloride levels was less than half of that of macrophages cultured without salt, and L. major infections were down as well.",We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control.,"[4.0, 5.0, 4.0, 3.0, 3.0]",Medicine,train,3.8,news,http://news.sciencemag.org/biology/2015/03/does-high-salt-diet-combat-infections
10.1038/s41467-018-04355-w,Medicine_374,They saw a significant decrease in lung metastases.,"Specifically, y = 9 when this ratio is the highest and y = 1 when this ratio is the lowest.","The researchers were able to reduce metastases by using a compound that blocks CCR2, a receptor on the surface of the inflammatory monocytes. They saw a significant decrease in lung metastases. Pecot said they want to continue investigating this strategy, and potentially other ways of preventing clotting within tumors, to see if it prevents metastases from initiating and whether it can stall the process once it has begun.","Clearly, this heatmap/matrix a i,j is symmetrical with respect to its main diagonal (a i*,j* = a j*,i* ). Specifically, y = 9 when this ratio is the highest and y = 1 when this ratio is the lowest. Notably, HR > 1 for each of these nine cell types, since when their density is ""high"" the prognosis, collectively speaking, is always less favorable (even though sometimes in a minor or negligible way, like in particular it happens for the M1 macrophages) than for LUSC patients, who have a ""low"" density of these immune cell types.","[1.0, 1.0, 2.0, 1.0]",Medicine,train,1.25,news,http://healthmedicinet.com/news/by-forming-clots-in-tumors-immune-cell-aids-lung-cancers-spread/
10.1007/s00213-014-3810-0,Medicine_375,"/ no comments

These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues

Your gut feeling could be causing your anxiety.",There were no associations of cortisol with attentional performance (all p>0.1).,"/ no comments

These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues

Your gut feeling could be causing your anxiety. There is a connection between anxiety and an upset gut. In the study, when the bacteria's healthy functions were restored, mood and behavior leveled out, reducing or eliminating anxious feelings.","Furthermore, there were no group differences in the overall cognitive status as assessed by digit span on the day of psychological testing. There were no associations of cortisol with attentional performance (all p>0.1). Results revealed that B-GOS prebiotic intake was associated with decreased waking salivary cortisol reactivity and altered attentional bias compared to placebo.","[1.0, 3.0, 1.0]",Medicine,train,1.6666666666666667,news,http://healthmedicinet.com/news/can-bacteria-cause-anxiety/
10.1038/s41598-017-18618-x,Medicine_377,"This study administered 30 cc of ACV per day and found that it created significantly reduced body weight, BMI, hip-circumference, visceral adiposity index, and appetite score.","Figure 3 depicts the effects of a dose dependent reduction in TNFα and IL-6 release from monocytes which have been co-cultured with ACV, together with either C. albicans, E-coli or S. aureus for 24 h.","This study administered 30 cc of ACV per day and found that it created significantly reduced body weight, BMI, hip-circumference, visceral adiposity index, and appetite score. In addition, plasma triglycerides and total cholesterol levels were decreased and HDL (good lipids) was increased in the ACV group. Weight checks are done at six and twelve-week intervals showed a significant reduction in BMI and body fat in this ACV group (Khezri et al, 2018).","Both sets of results were also confirmed further by microdilution. Figure 3 depicts the effects of a dose dependent reduction in TNFα and IL-6 release from monocytes which have been co-cultured with ACV, together with either C. albicans, E-coli or S. aureus for 24 h. Consistent with the microbial growth inhibition data depicted in Fig.","[2.0, 1.0, 1.0, 2.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=39098464353&p=1pl&v=1&x=1oF0R8OHMp2RCFFanDJNtw
10.1016/j.mayocp.2014.07.004,Medicine_378,"""As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support.","The use of NRT bought over the counter was associated with a lower odds of abstinence (odds ratio, 0.68; 95% CI, 0.49-0.94).","A combination of prescription medication along with limited behavioral support was also more effective than unaided quitting. ""As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support. A major strength of our study is the use of a representative sample of the English population that was sufficiently large to detect an effect of specialist behavioral support despite its low prevalence,"" says Dr. Kotz.","Results: Compared with smokers using none of the cessation aids, the adjusted odds of remaining abstinent up to the time of the 6-month follow-up survey were 2.58 (95% CI, 1.48-4.52) times higher in users of prescription medication in combination with specialist behavioral support and 1.55 (95% CI, 1.11-2.16) times higher in users of prescription medication with brief advice. The use of NRT bought over the counter was associated with a lower odds of abstinence (odds ratio, 0.68; 95% CI, 0.49-0.94). Conclusion: Prescription medication offered with specialist behavioral support and that offered with minimal behavioral support are successful methods of stopping cigarette smoking in England.","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,news,http://www.sciencedaily.com/releases/2014/10/141008083514.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41467-019-09863-x,Medicine_379,"But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev.","For the PCF, the legacy value is zero emissions from permafrost since the PCF is not included in most climate projections using GCMs 18 .","""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost. But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev. ""The most important thing to remember about our study is the greater the warming, the stronger the feedbacks and the higher the costs to society.""","Figure 3 shows the medians and 25-75% ranges for the GMST projections relative to pre-industrial levels for the climate scenarios considered, obtained using PAGE-ICE with the legacy values of the PCF and SAF. For the PCF, the legacy value is zero emissions from permafrost since the PCF is not included in most climate projections using GCMs 18 . Further details appear in Methods.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1073/pnas.1504869112,Medicine_38,"Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more.","This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets.","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","By impacting on tree growth and survival, lianas impact the carbon balance of these forests. This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets. Lianas are increasing in biomass and productivity throughout the tropics, and thus our findings have even greater relevance in terms of the fate of the tropical carbon balance, as well as for global atmospheric CO 2 levels, in a changing climate.","[3.0, 5.0, 5.0, 4.0]",Medicine,train,4.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1186/gb-2013-14-7-r73,Medicine_380,"Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients.",It's tantalizing to speculate that these RNAs could participate in the complex machinery that supports the pluripotent-like properties of cancerous cells.,"Researchers found that some of these vlincRNAs are co-opted by cancer-associated transcriptional programs. Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients. VlincRNAs may contribute to the regulation of gene expression in the nucleus of the cell.","In this respect, it's reminiscent of very recent studies showing the prominent importance of cancer stem cells in disease . It's tantalizing to speculate that these RNAs could participate in the complex machinery that supports the pluripotent-like properties of cancerous cells. Here we provide evidence that these cellular transcripts, rather than the LTRs themselves, constitute another component mediating the function of ERVs in pluripotency and malignancy.","[3.0, 3.0, 1.0, 1.0, 2.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamaophthalmol.2017.4655,Medicine_381,"For each BCVA criterion, the total annual incidence was 12.4 percent of the total prevalence.","If the death rate has been underestimated for the LV population, then the annual LV incidence rate also has been underestimated.","The researchers found that among older adults (>=45 years) in 2017, the prevalence of low vision and blindness was estimated at 3,894,406 individuals with a best corrected visual acuity (BCVA) less than 20/40, 1,483,703 individuals with a BCVA less than 20/60, and 1,082,790 individuals with a BCVA of 20/200 or less. For each BCVA criterion, the total annual incidence was 12.4 percent of the total prevalence. ""Prevalence and incidence rates show a substantial increase in the need for low vision rehabilitation services with the aging of the US population,"" the authors write.","17 In addition, it is possible, if not probable, that LV increases death rates because LV increases the risk of falls, 18-22 medication mismanagement, 24 and reduced activity levels. If the death rate has been underestimated for the LV population, then the annual LV incidence rate also has been underestimated. The risk of age-related eye disease increases with increasing age, 29 which explains the acceleration of the LV prevalence rate with age ( Figure 3 ).","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.physiciansbriefing.com/Article.asp?AID=728151
10.1098/rsos.150710,Medicine_382,"""The findings suggest it's not so easy to increase good behaviour using online cues such as images, and that's an interesting finding given the level of interest in looking at how we behave online and what might influence online behaviour,"" he says.",This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online charity donation on MTurk.,"Study co-author Associate Professor Quentin Atkinson says none of the 'monitoring cues' such as human faces or simply a pair of watching eyes, worked to increase donations. ""The findings suggest it's not so easy to increase good behaviour using online cues such as images, and that's an interesting finding given the level of interest in looking at how we behave online and what might influence online behaviour,"" he says. ""This study suggests that traditional factors, such as age, culture or ethnicity, and in particular a past history of giving to charity, have a greater effect on how altruistic we choose to be.""","By contrast, the control variables of culture, age, sex and previous charity giving frequency did predict donations. This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online charity donation on MTurk. None of the monitoring primes we tested had a significant effect on charitable giving.","[3.0, 2.0, 4.0]",Medicine,train,3.0,news,http://healthmedicinet.com/news/do-online-tools-change-online-behaviour/
10.1098/rspb.2013.3172,Medicine_383,"According to Professor Bauch, as that trend continues Canadians will increasingly find themselves in a situation where vaccination coverage has declined and populations are once again susceptible to disease.","Viewed from this perspective, the whole-cell pertussis vaccine scare of the 1970s interrupted an otherwise steady climb in vaccine coverage that was converging towards the E 1 equilibrium.","Obviously, when enough parents are no longer vaccinating, the disease will come back."" According to Professor Bauch, as that trend continues Canadians will increasingly find themselves in a situation where vaccination coverage has declined and populations are once again susceptible to disease. ""Parents are not cold, clinical rationalists who base their decisions only on data.","The long-term effects of the scare are apparent in the continued discrepancy between vaccine coverage with and without the scare as late as 2010, which is 30 years after perceived vaccine risk was modelled to have returned to baseline levels. Viewed from this perspective, the whole-cell pertussis vaccine scare of the 1970s interrupted an otherwise steady climb in vaccine coverage that was converging towards the E 1 equilibrium. As a result, they predict that it should be difficult or impossible to eliminate a paediatric infectious disease through voluntary vaccination programmes.","[2.0, 4.0, 2.0, 4.0]",Medicine,train,3.0,news,http://www.sciencedaily.com/releases/2014/02/140214111211.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2015.0500,Medicine_387,"In 2010, it began at 0.11 percent among ages 1 to 6.","In the community, the prevalence of adolescents with severe impairment is 8.7% for depression, 4.3% for ADHD, and 2.6% for bipolar disorder.","The percentage dropped to about half a percent by the time they reach the age of 19. In 2010, it began at 0.11 percent among ages 1 to 6. Then it increased to 0.80 percent among ages 7 to 12.","41 In our study, among adolescents treated with antipsychotics who had diagnosed psychiatric disorders, the most common diagnoses were ADHD (34.9%), followed by depression (24.4%) and bipolar disorder (20.5%). In the community, the prevalence of adolescents with severe impairment is 8.7% for depression, 4.3% for ADHD, and 2.6% for bipolar disorder. These proportions suggest that adolescents with severely impairing ADHD or bipolar disorder may be more likely than those with severely impairing depression to receive antipsychotic treatment.","[1.0, 2.0, 2.0, 1.0, 2.0]",Medicine,train,1.6,news,http://www.techtimes.com/articles/65576/20150702/boys-with-adhd-more-likely-to-be-given-antipsychotics-study.htm
10.1126/science.aat9688,Medicine_388,"The team hopes that their new technique will open the door for lots of new experiments and discoveries at the nanoscale, thanks to the options that it provides for the first time.","The STM tunneling current, however, can generate excited states of a molecule and hence give enhanced specificity, and more varied outcomes, to the manipulation action [e.g., bond dissociation (4, 5) , isomerization (6), or tautomerization (7) ].","Essentially we have a new dial we can set when running our experiment. The extreme nature of working on these scales makes it hard to do, but we have extreme resolution and reproducibility with this technique."" The team hopes that their new technique will open the door for lots of new experiments and discoveries at the nanoscale, thanks to the options that it provides for the first time.","Through the mechanical interaction between tip and target molecule, or by the electric field in the gap, the STM can induce molecular change across a groundstate potential energy landscape (3) . The STM tunneling current, however, can generate excited states of a molecule and hence give enhanced specificity, and more varied outcomes, to the manipulation action [e.g., bond dissociation (4, 5) , isomerization (6), or tautomerization (7) ]. The specificity arises by controlling the energy (5) or position (7, 8) of the single electron (or hole) excitation within a single molecule.","[2.0, 3.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=37038008290&p=1pl&v=1&x=cdTv0tZ1tttrqFN7rPlSvA
10.1073/pnas.1318978111,Medicine_390,"""If these data are confirmed in clinical trials, we could propose that raising low levels of androgens in a woman with diminished ovarian reserve might increase her ability to produce more and better eggs for fertilization.""",involve paxillin-mediated synergistic action between nuclear and extranuclear signaling of ARs that induces expression of the antiapoptotic miR-125b and up-regulates expression of the proproliferative FSHR.,"""This information is important because it provides theoretical support for administering androgens to some women undergoing IVF, a practice that our fertility clinic and many others across the country have started in recent years,"" said Hoeger, who is also a professor of Obstetrics and Gynecology at the School of Medicine and Dentistry. ""If these data are confirmed in clinical trials, we could propose that raising low levels of androgens in a woman with diminished ovarian reserve might increase her ability to produce more and better eggs for fertilization."" Hammes says the study calls for further clinical trials to determine whether androgens can have a positive effect on fertility when given at the right doses.","In vivo knockdown of miR-125b-2 increases follicular atresia. involve paxillin-mediated synergistic action between nuclear and extranuclear signaling of ARs that induces expression of the antiapoptotic miR-125b and up-regulates expression of the proproliferative FSHR. Our study not only demonstrates miR125b as an important regulator of follicular atresia, but also provides detailed insight as to the hormonal regulation of miR125b by androgens in the ovary.","[1.0, 2.0, 1.0, 1.0]",Medicine,train,1.25,news,http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/chemse/bjt066,Medicine_391,"When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label.","Specifically, the effect was also seen for the 2 nonfood odorants suggesting an unbiased effect.","When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.","All odorants presented with positive labels were rated as being more edible than when they were presented with negative labels. Specifically, the effect was also seen for the 2 nonfood odorants suggesting an unbiased effect. All odorants presented with positive labels were rated as being more pleasant than when they were presented with negative labels.","[4.0, 1.0, 1.0, 2.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.180695,Medicine_392,"We could also be adapting to the cozy indoor climates where we spend most of our time, speculates Gilligan.","Moreover, predictions can be made about the communities of home associates through time and space, as climate, home technologies and fortunes change.","Gilligan said he would be interested to see how people keep their houses in other parts of the world, since there may be differences in preference based on culture and genetics. We could also be adapting to the cozy indoor climates where we spend most of our time, speculates Gilligan. And while the inside of a house may be similar to an African savannah, the house will probably stay more constant than any real outdoor climate.","Our results also offer a hypothesis about the likely origin of human home-associated species, as indoor climates probably favour certain lineages, those pre-adapted to indoor climates. Moreover, predictions can be made about the communities of home associates through time and space, as climate, home technologies and fortunes change. We know that climate preferences in homes differ among regions , and the USA is probably an extreme case, where indoor climates most reflect resource availability and culture, rather than economic and environmental costs.","[1.0, 3.0, 4.0, 4.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=38798635240&p=1pl&v=1&x=dKEYUvmyKXnUNRgeE2st1A
10.1534/genetics.116.197285,Medicine_394,"""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said.","Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow.","Yet, faced with the new and sophisticated CRISPR/Cas9 method of gene drive, nature is still likely to fight back to resist the mutation successfully, Unckless said. ""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said. They show nature still has the edge over scientists hoping to solve human problems with GM organisms.","We find that in most scenarios P SGV is higher than P μ . Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow. The key parameter determining the likelihood of resistance from NHEJ is the product N e δ, similar to the role played by θ = 4N e μ for de novo mutation.","[3.0, 2.0, 4.0, 3.0, 4.0]",Medicine,train,3.2,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1002/hec.3070,Medicine_395,A 20 per cent sales tax would raise annual costs per person by about $15 to $17.,"show that a 20% increase in price will lead to reductions in consumption of 17.67%, 46.5% and 20.03% of regular soft drinks, cordial and fruit juice respectively.","Although both taxes would be regressive, representing a greater proportion of lower incomes than higher ones, the proposed rates would keep this effect mild, Dr Sharma said. A 20 per cent sales tax would raise annual costs per person by about $15 to $17. But in weight-loss terms, average consumption would drop by more than 10,000 kilojoules a quarter, with about one third of a kilo coming off on the scales.","These effects are expressed in percentage changes in quantities of all ten non-alcoholic beverages once the 20% tax is applied on regular soft drinks, cordial and fruit drinks. show that a 20% increase in price will lead to reductions in consumption of 17.67%, 46.5% and 20.03% of regular soft drinks, cordial and fruit juice respectively. The consumption of the taxed SSBs is also affected indirectly through cross-price elasticities.","[3.0, 1.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2014/06/140617094037.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1403984111,Medicine_396,The data also show that the destination of the illegally trafficked ivory increasingly shifted to China.,"At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China.","This surge was directly correlated to a more than quadrupling of local black-market ivory prices paid to poachers and tripling in the volume and number of illegal ivory seizures through Kenyan ports of transit. The data also show that the destination of the illegally trafficked ivory increasingly shifted to China. Such figures cause conservationists alarm, as the study shows over 54 percent is a level of poaching that elephant birth rates are unable to overcome and will lead to population decline.","At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year. Preliminary data from 2013 indicate overharvesting continued.","[4.0, 4.0, 4.0, 3.0, 3.0]",Medicine,train,3.6,news,http://www.newswise.com/articles/colorado-state-university-study-verifies-more-than-100-000-african-elephants-killed-in-three-years
10.1073/pnas.1424293112,Medicine_397,"The discovery of their existence, outlined this week in a study in The Proceedings of the National Academy of Sciences, brings researchers one-step closer to fully understanding how the fungus attacks and kills trees.","Most of the M. populorum secondary metabolite cluster proteins were found nested within a group of Eurotiomycetes fungi, including P. oxalicum, as expected under the hypothesis that the cluster was transferred from a Eurotiomycetes ancestor through a horizontal transfer event ( Fig.","The discovery of their existence, outlined this week in a study in The Proceedings of the National Academy of Sciences, brings researchers one-step closer to fully understanding how the fungus attacks and kills trees. ""Our findings will help us develop better methods to detect the fungus and prevent its spread,"" says senior author Richard Hamelin, a UBC forestry professor and research scientist at Natural Resources Canada. ""It's probably rare, but it appears to be more common than we ever thought.""","The striking conservation in synteny and gene sequence as well as the sporadic distribution of the full cluster in only two groups of the fungal phylogeny (Dothideomycetes and Eurotiales) raises the possibility that this cluster was acquired through horizontal gene transfer (HGT) (Fig. Most of the M. populorum secondary metabolite cluster proteins were found nested within a group of Eurotiomycetes fungi, including P. oxalicum, as expected under the hypothesis that the cluster was transferred from a Eurotiomycetes ancestor through a horizontal transfer event ( Fig. 2B ; Dataset S2; SI Appendix, Origin and evolutionary history of the chaetoglobosin-like gene cluster in M. populorum).","[1.0, 3.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2015/03/150304104352.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1186/2045-5380-3-19,Medicine_398,"But, the stabilizing effects of CBD can help patients through withdrawal.","As hippocampal volume is known to be reduced in major depression , and reduced hippocampal volume is thought to be a risk factor in PTSD , these data would suggest that polymorphisms in the CNR1 gene that result in greater CB1 receptor activity may result in increased hippocampal volume and thus provide a neural substrate mediating a protective effect.","That said, due to the withdrawal symptoms of Adderall, those with ADHD should consult their doctor before changing their treatment. But, the stabilizing effects of CBD can help patients through withdrawal. And, CBD also offers continuing support as an effective alternative to Adderall in the long-term.","Taken together, these studies would suggest that the A allele in the rs1049353 polymorphism of the CNR1 gene results in some level of protection against the development of depression, particularly in response to stress exposure. As hippocampal volume is known to be reduced in major depression , and reduced hippocampal volume is thought to be a risk factor in PTSD , these data would suggest that polymorphisms in the CNR1 gene that result in greater CB1 receptor activity may result in increased hippocampal volume and thus provide a neural substrate mediating a protective effect. Future studies should thoroughly investigate the role of this polymorphism in psychiatric illness, and also determine if the rs1049353 polymorphism has a similar effect on CB1 receptor density in humans to understand how these gene variants could impact disease progression.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1007/s13524-014-0321-x,Medicine_399,The happiness level of parents varied among different ages.,We assume the cardinality of life satisfaction because treating life satisfaction as ordinal versus cardinal makes little difference .,"On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.","We experimented with both measures, and like , we found that our results were very similar independent of the measure, the key difference being the loss in statistical power for the sporadically measured life satisfaction. We assume the cardinality of life satisfaction because treating life satisfaction as ordinal versus cardinal makes little difference . Our modeling approach, which follows with some modifications, 5 allows observing anticipation, shortterm (1 to 4 years) changes, and long-term (5 to 18 years) changes in happiness over the transition to parenthood while controlling for time-invariant unobserved characteristics, such as personality or genetic endowments.","[1.0, 2.0, 1.0, 1.0]",Medicine,train,1.25,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1001/jama.2018.20578,Medicine_4,">>

Le Dr. Zheng a explique que l'usage de l'aspirine devrait donner lieu a une discussion entre les patients et les medecins, et leur preciser que toute amelioration de leur sante cardiovasculaire, meme minime, implique << un reel risque d'hemorragie grave >>.","In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.","Cette etude montre que, si les incidents cardiovasculaires peuvent etre reduits chez ces patients, les avantages sont confrontes a un plus grand risque d'incidents hemorragiques majeurs. >>

Le Dr. Zheng a explique que l'usage de l'aspirine devrait donner lieu a une discussion entre les patients et les medecins, et leur preciser que toute amelioration de leur sante cardiovasculaire, meme minime, implique << un reel risque d'hemorragie grave >>. Certains des participants prenaient de l'aspirine tandis que d'autres avaient un placebo ou rien du tout.","19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[1.0, 1.0, 4.0, 5.0, 3.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=38330869620&p=1pl&v=1&x=M8k770LVWvQytywr57cyKg
10.1016/j.childyouth.2014.05.001,Medicine_400,"Low levels of self-esteem and poor emotional processing skills were significantly correlated with gang involvement, as were low levels of parental monitoring, poor parental communication and housing instability.","Major findings also indicated that low levels of parental monitoring, poor parental communication and housing instability were significantly associated with gang involvement.","Among the 188 participants, 66 percent reported having received food stamps, 58 percent reported housing instability (either being thrown out of their house or running away from home), 52 percent reported living in neighborhoods with poor quality (living on a street with abandoned homes or apartments; buildings with broken windows; and/or homes with bars on the windows and doors) and 27 percent indicated gang involvement. Low levels of self-esteem and poor emotional processing skills were significantly correlated with gang involvement, as were low levels of parental monitoring, poor parental communication and housing instability. ""Adolescents who have strained relationships with positive family and community members and have displaced housing may find a sense of belonging with gangs,"" Voisin said.","Similarly, our findings support earlier studies documenting that emotional processing ability has been associated with the quality of social interactions with both friends and family , and antisocial behavior and delinquency over time ). Major findings also indicated that low levels of parental monitoring, poor parental communication and housing instability were significantly associated with gang involvement. Our findings support social control theory .","[2.0, 4.0, 5.0, 5.0]",Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/08/140827151656.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10484-015-9286-9,Medicine_402,"""Because evidence shows that low HRV is a potential risk factor for sexual dysfunction, physicians have a simple, low-cost and nonintrusive method to measure a woman's risk for sexual dysfunction,"" said Stanton.","In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction.","With recent support from the Food and Drug Administration on what could be the first-ever approved drug for the treatment of female sexual dysfunction, the researchers believe that HRV could be used as an index of drug-related changes in sexual function. ""Because evidence shows that low HRV is a potential risk factor for sexual dysfunction, physicians have a simple, low-cost and nonintrusive method to measure a woman's risk for sexual dysfunction,"" said Stanton. ""It makes it easier to talk about something a little bit more private and get women the help that they need.""","Women with below average HRV were significantly more likely to report sexual arousal dysfunction (p \ .001) and overall sexual dysfunction (p \ .001) than both women with average HRV and women with above average HRV. In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction. Given these findings, it is reasonable to expect ANS activity (indexed by HRV) may be related to women's self-reported, real-life sexual arousal function outside of the laboratory.","[4.0, 5.0, 4.0, 4.0, 4.0]",Medicine,train,4.2,news,http://www.newswise.com/articles/study-links-heartbeat-to-female-libido
10.1007/s10803-013-1920-x,Medicine_403,No child had both SCQ and ADOS scores in the relevant ranges that would lead to an ASD diagnosis.,"In this study, not one child met strict diagnostic criteria for ASD using results of both the ADOS and SCQ.","Only two -- 7 percent -- had SCQ scores above the cut off. No child had both SCQ and ADOS scores in the relevant ranges that would lead to an ASD diagnosis. It's quite clear that children with the disorder do have social impairments,"" Simon said.","While it is important to note that research evaluations are not substitutes for clinical evaluations, it is useful to examine the yield of ASD diagnoses based on criteria that more closely resemble what is used in clinical practice (both directly administered assessment and parental history). In this study, not one child met strict diagnostic criteria for ASD using results of both the ADOS and SCQ. Given the similar prevalence rates (44-68 %) we found based on BASC-PRS, it seems that the difference in diagnostic methodology is the primary reason for the discrepancy between the percentage of children meeting criteria for an ASD diagnosis in our study and the prevalence of ASD in the 22q11.2DS literature for children in this age range Niklasson et al.","[5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/09/130918090845.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13058-018-1049-0,Medicine_404,"Using this research, physicians could monitor their patients with bone marrow aspirates.","This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD .","The research is especially important in the United States because bone marrow tests, called aspirates, are not used to monitor patients there. Using this research, physicians could monitor their patients with bone marrow aspirates. Tests for the protein could also help clinicians identify patients who may benefit from recently identified drugs that were shown to target cancer cells and render or keep them dormant.","Improved techniques to assess the MRD population and their dormant or reactivating state will be key to identifying the risk of future metastasis despite undergoing standard treatment. This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD . These drugs will be tested in a clinical trial of prostate cancer patients at risk of developing metastasis (Mount Sinai IRB no.","[1.0, 2.0, 2.0, 4.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=37400845010&p=1pl&v=1&x=9kQQeeV3wfEGbY0w3Hhy5Q
10.1111/psyp.12228,Medicine_408,"By 35 weeks, the fetus responds to familiar music with a change in movement patterns.","Note, however, that this may not be a mechanism of prenatal cultural transfer specific to music, but that physiological responses in Enhanced response to music in pregnancypregnant women may be enhanced to acoustic stimulation in general, a question that is not addressed in the current study.","However, non-pregnant women were taking birth control contraceptives, which influences estrogen levels greatly and they did not register the same strong emotions that pregnant women had felt toward each type of music. By 35 weeks, the fetus responds to familiar music with a change in movement patterns. Enhanced Response To Music In Pregnancy.","Our finding suggests that the physiological response of the mother is enhanced with respect to a specific type of acoustical stimulus, namely, music, which may in turn partly underlie the strong physiological effects of music on the listener. Note, however, that this may not be a mechanism of prenatal cultural transfer specific to music, but that physiological responses in Enhanced response to music in pregnancypregnant women may be enhanced to acoustic stimulation in general, a question that is not addressed in the current study. Interestingly, the observed effects of music on the measured cardiac values (continuous blood pressure) are not directly related to valence, as has been previously speculated with respect to heart rate .","[3.0, 5.0, 2.0, 3.0, 2.0]",Medicine,train,3.0,news,http://www.medicaldaily.com/pregnant-women-have-stronger-response-music-enough-raise-their-blood-pressure-284496
10.1001/jama.2018.20578,Medicine_41,"They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding.",Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared with no aspirin (57.1 per 10 000 participant-years with aspirin and 61.4 per 10 000 participant-years with no aspirin) (hazard ratio CONCLUSIONS AND RELEVANCE The use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.,"They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding. The results showed that:

Aspirin use was associated with an 11% lower risk of cardiovascular events. Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death.","The median age of trial participants was 62 years (range, 53-74), 77 501 (47%) were men, 30 361 (19%) had diabetes, and the median baseline risk of the primary cardiovascular outcome was 9.2% (range, 2.6%-15.9%). Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared with no aspirin (57.1 per 10 000 participant-years with aspirin and 61.4 per 10 000 participant-years with no aspirin) (hazard ratio CONCLUSIONS AND RELEVANCE The use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[5.0, 5.0, 3.0]",Medicine,train,4.333333333333333,news,https://www.sciencedaily.com/releases/2019/01/190122114950.htm
10.1038/s41598-018-25671-7,Medicine_411,"The researchers acknowledge that YouTube videos of dog bites are likely subject to some bias, with, for example, bites by small dogs perhaps perceived as ""comical"" and therefore more likely to be uploaded online.",We also did not include a breed as a predictor variable due to documented problems in recognising a breed based on visual characteristics 30 and a small number of dogs in each breed category.,"For 56 of these videos they were also able to analyse the details of human and dog behaviour leading up to the bite. The researchers acknowledge that YouTube videos of dog bites are likely subject to some bias, with, for example, bites by small dogs perhaps perceived as ""comical"" and therefore more likely to be uploaded online. The findings reveal that despite this potential bias, the demographic characteristics of the victims and dogs seen in YouTube bite videos, such as breed type and victims' sex and age, are consistent with those found in previous studies.","Moreover, not all variables which are often cited in literature as risk factors for bites were used as predictor variables in our model as it was not always possible to discern them from the video. We also did not include a breed as a predictor variable due to documented problems in recognising a breed based on visual characteristics 30 and a small number of dogs in each breed category. One approach that could be utilised in the future on larger samples is systems-style modelling, such as using network analysis, that would identify interactive effects between variables that result in bites occurring and/or influence bite severity.","[3.0, 3.0, 2.0, 2.0]",Medicine,train,2.5,news,http://ct.moreover.com/?a=34019053777&p=1pl&v=1&x=5nYw5SbVJSqoLC3Qtatd9A
10.1001/jamaoncol.2018.2254,Medicine_413,"The researchers identified 1,063 deaths during a median follow-up of 9.6 years.",There was a significant inverse association across quartiles of exercise and all-cause mortality after adjusting for chronic health conditions and treatment exposures (P = .02 for trend).,"The researchers identified 1,063 deaths during a median follow-up of 9.6 years. At 15 years, the cumulative incidence of all-cause mortality was 11.7, 8.6, 7.4, and 8 percent for those who exercised zero, three to six, nine to 12, and 15 to 21 MET-hours/week, respectively. After adjustment for chronic health conditions and treatment exposures, a significant inverse association was seen across quartiles of exercise and all-cause mortality (P = 0.02 for trend).","At 15 years, the cumulative incidence of all-cause mortality was 11.7% (95% CI, 10.6%-12.8%) for those who exercised 0 MET-h/wk, 8.6% (95% CI, 7.4%-9.7%) for 3 to 6 MET-h/wk, 7.4% (95% CI, 6.2%-8.6%) for 9 to 12 MET-h/wk, and 8.0% (95% CI, 6.5%-9.5%) for 15 to 21 MET-h/wk (P < .001). There was a significant inverse association across quartiles of exercise and all-cause mortality after adjusting for chronic health conditions and treatment exposures (P = .02 for trend). Among a subset of 5689 survivors, increased exercise (mean [SD], 7.9 [4.4] MET-h/wk) over an 8-year period was associated with a 40% reduction in all-cause mortality rate compared with maintenance of low exercise (rate ratio, 0.60; 95% CI, 0.44-0.82; P = .001).","[3.0, 2.0, 2.0, 1.0, 1.0]",Medicine,train,1.8,news,http://ct.moreover.com/?a=34289670602&p=1pl&v=1&x=a-vHk9gR3QeZmhOGRMfTUQ
10.1080/08870446.2014.918267,Medicine_414,"Interestingly, in the second experiment, overweight viewers of food ads reported a stronger desire to eat than those in the control group.",The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products.,"Researchers found that in both experiments, those shown food ads produced more food related words, suggesting that the advertising does activate increased food-related cognitions. Interestingly, in the second experiment, overweight viewers of food ads reported a stronger desire to eat than those in the control group. Experiment 1 participants reported a lower desire to eat across the board.","In contrast to Experiment 1, exposure to television food advertising also affected ratings of desire to eat. The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products. This suggests that in overweight and obese individuals, exposure to food commercials not only activates food-related cognitions, but also triggers a motivation to eat.","[4.0, 2.0, 3.0, 4.0]",Medicine,train,3.25,news,http://www.hngn.com/articles/40594/20140828/food-advertisements-make-eat-more-study-confirms.htm
10.1073/pnas.1418572112,Medicine_415,Children who had acquired a hostile attributional bias were more likely than other children to grow in the rate and severity of their aggressive behavior across the four years of the study.,"As expected, motherrated and child-rated chronic aggressive behavior problem scores were significantly correlated with each other and with similar scores across years.","In fact, on average, they were five times more likely to do so than children who accepted the act as non-hostile. Children who had acquired a hostile attributional bias were more likely than other children to grow in the rate and severity of their aggressive behavior across the four years of the study. Expanded Golden Rule

Most importantly, the cultures that had the highest rates of hostile attributional bias, such as Zarqa, Jordan, and Naples, Italy, also had the highest rates of child aggressive behavior problems.","Likewise, internal consistency of individual differences in selfpredicted reactive aggression was high overall (ρ = 0.95; 95% CI: 0.94, 0.96) and in each group. As expected, motherrated and child-rated chronic aggressive behavior problem scores were significantly correlated with each other and with similar scores across years. Hostile attributional bias scores in year 3 were significantly correlated with both mother-rated and child-rated chronic aggressive behavior problem scores in each of years 2, 3, and 4.","[3.0, 3.0, 3.0, 4.0]",Medicine,train,3.25,news,http://www.futurity.org/children-hostility-violence-960852/
10.1073/pnas.1614389114,Medicine_417,"""Pride appears to be an elegantly engineered emotion: It makes you pursue socially valued courses of action, and it facilitates the gains in esteem that make those actions worth pursuing.""","This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation.","This may explain why pride is a target of righteous indignation around the world. ""A careful mapping of this emotion suggests a different view, however,"" he continues. ""Pride appears to be an elegantly engineered emotion: It makes you pursue socially valued courses of action, and it facilitates the gains in esteem that make those actions worth pursuing.""","Further, pride is specific to audience valuation: Emotions that co-activate with pride, such as happiness and excitement, do not track audience valuation uniquely and reliably. This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation. Further evidence to demonstrate domain-specificity is needed, however.","[4.0, 5.0, 4.0, 5.0, 5.0]",Medicine,train,4.6,news,http://www.futurity.org/pride-evolution-emotions-1357352-2/
10.1098/rsos.172398,Medicine_418,A new study on dog behavior may help us better understand how human personalities affect obesity.,"These results are very similar to those expected from the parallel models that exist between certain personality traits and being overweight in humans, suggesting that dogs are indeed a promising model for experimentally investigating obesity in humans.","A new study on dog behavior may help us better understand how human personalities affect obesity. The scientists thought that the obese dogs would be more likely to wait for the potential high-value meal, that they would do anything for something big and tasty. However, that was not the case.","Our results also confirm that overweight dogs, as opposed to normal weight dogs, tried to maximize food intake from the higher quality food and hesitated to do the task when the food reward was uncertain. These results are very similar to those expected from the parallel models that exist between certain personality traits and being overweight in humans, suggesting that dogs are indeed a promising model for experimentally investigating obesity in humans. Dogs, due to their shared living environment with humans, may provide a beneficial model to study the causes and consequences of obesity.","[3.0, 5.0, 4.0, 4.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=34325969822&p=1pl&v=1&x=salba5rYf-HICBtD5mnRpg
10.1016/j.biopsych.2013.07.024,Medicine_419,"Associations between prenatal exposure to both glucocorticoids -- particularly cortisol -- and tobacco smoke emerged only for daughters, which Stroud says it consistent with some recent research findings.","Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid exposure (60), we also hypothesized that links between prenatal glucocorticoids and offspring ND would be stronger for daughters.","Because mothers who smoke are often more stressed and living in adverse conditions -- these findings represent a public health concern and highlight the need to help smoking moms quit and reduce stress levels and improve social conditions for poor pregnant mothers,"" Stroud added. Associations between prenatal exposure to both glucocorticoids -- particularly cortisol -- and tobacco smoke emerged only for daughters, which Stroud says it consistent with some recent research findings. ""Our findings highlight the particular vulnerability of daughters to long-term adverse outcomes following maternal stress and smoking during pregnancy,"" she said.","Thus, we propose that maternal cortisol levels might mediate the relation between MSDP and offspring ND. Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid exposure (60), we also hypothesized that links between prenatal glucocorticoids and offspring ND would be stronger for daughters. showed associations between fetal testosterone exposure and alterations in responsiveness of neural reward regions and behavioral approach tendencies, both of which have been associated with ND .","[4.0, 3.0, 5.0, 4.0]",Medicine,train,4.0,news,http://psychcentral.com/news/2013/10/08/risk-for-nicotine-addiction-tied-to-mothers-childbirth-stress/60475.html
10.1038/s41593-018-0289-8,Medicine_421,"""Our current study reinforces growing evidence suggesting that A-beta and tau work together to impair brain function and that, for certain aspects of that impairment, tau predominates.","Again, ELISA analysis showed a substantial reduction in total human tau levels in all mice receiving DOX ( Supplementary Fig.","The findings suggest that strategies directed against both pathologic proteins, rather than one or the other, might be promising therapeutic options. ""Our current study reinforces growing evidence suggesting that A-beta and tau work together to impair brain function and that, for certain aspects of that impairment, tau predominates. Studies with two mouse models that overexpress different forms of tau found, for the first time, that elevated levels of the protein were associated with a significant reduction in neural activity whether or not tau had aggregated into tangles.","), demonstrating that the difference between the effects of DOX treatment in the young rTg4510 and APP/PS1-rTg4510 mice were highly significant. Again, ELISA analysis showed a substantial reduction in total human tau levels in all mice receiving DOX ( Supplementary Fig. As a control, we treated wild-type control mice with DOX and found no significant effects (Supplementary Fig.","[2.0, 2.0, 1.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=38148348820&p=1pl&v=1&x=3selMPRuYABgNhN6T6VMqw
10.1111/infa.12017,Medicine_422,"""This is the first study to show a matching ability with an infant this young.",The present findings are the first to show 5-month-olds match the faces and voices of other infants on the basis of global invariant properties common to facial and vocal emotional expressions.,"""We found that 5 month old infants can match their peer's positive and negative vocalizations with the appropriate facial expression,"" says Flom. ""This is the first study to show a matching ability with an infant this young. They are exposed to affect in a peer's voice and face which is likely more familiar to them because it's how they themselves convey or communicate positive and negative emotions.""","These temporal and intensity patterns are invariant across face and voice and may specify different emotional valences which can be detected only in dynamic, moving expressions ) where changes in intensity and temporal patterns are evident. The present findings are the first to show 5-month-olds match the faces and voices of other infants on the basis of global invariant properties common to facial and vocal emotional expressions. Infants' intermodal matching of facial and vocal affective information in unfamiliar peers appears to emerge somewhat earlier (by 5 months but not 3.5 months of age) than their matching of facial and vocal affective information in unfamiliar adults (by 7 months but not 5 months of age; ) .","[5.0, 5.0, 5.0, 3.0, 3.0]",Medicine,train,4.2,news,http://www.healthcanal.com/mental-health-behavior/40222-babies-can-read-each-other%E2%80%99s-moods%2C-study-finds.html
10.1126/sciadv.1400121,Medicine_423,"These immune signatures represent the first robust physical evidence that ME/CFS is a biological illness as opposed to a psychological disorder, and the first evidence that the disease has distinct stages.","Integration of these immune markers with clinical findings will provide clinicians with a stronger framework for establishing an ME/CFS diagnosis, and, possibly, make it easier to rule out other conditions at an earlier time point.","The findings could help improve diagnosis and identify treatment options for the disabling disorder, in which symptoms range from extreme fatigue and difficulty concentrating to headaches and muscle pain. These immune signatures represent the first robust physical evidence that ME/CFS is a biological illness as opposed to a psychological disorder, and the first evidence that the disease has distinct stages. They found specific patterns in patients who had the disease three years or less that were not present in controls or in patients who had the disease for more than three years.","First, we were able to define a distinctive immune signature that differed from that of healthy controls. Integration of these immune markers with clinical findings will provide clinicians with a stronger framework for establishing an ME/CFS diagnosis, and, possibly, make it easier to rule out other conditions at an earlier time point. It may also facilitate resolution of some of the clinical heterogeneity observed in this illness by enhancing the ability to distinguish cytokine-associated phenotypes from ME/CFS subsets wherein disease may be triggered by nonimmunologic factors.","[2.0, 3.0, 3.0, 4.0]",Medicine,train,3.0,news,http://www.sciencedaily.com/releases/2015/02/150227144903.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamainternmed.2013.6536,Medicine_425,"advertisement

The authors uncovered a striking benefit: Men who replaced 10 percent of their total daily calories from carbohydrates with healthy vegetable fats had a 29 percent lower risk of developing lethal prostate cancer and a 26 percent lower risk of dying from all causes.","In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality.","During the study timeframe, 1,064 men died, primarily from cardiovascular disease (31 percent), prostate cancer (21 percent) and other cancers (nearly 21 percent). advertisement

The authors uncovered a striking benefit: Men who replaced 10 percent of their total daily calories from carbohydrates with healthy vegetable fats had a 29 percent lower risk of developing lethal prostate cancer and a 26 percent lower risk of dying from all causes. More Study Needed on Potential Benefits of Healthy Fats

Adding a single serving of oil-based dressing a day (one tablespoon) was associated with a 29 percent lower risk of lethal prostate cancer and a 13 percent lower risk of death, the authors found.","Post-diagnostic intakes of mayonnaise and margarine were not associated with risk of lethal prostate cancer or all-cause mortality. In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality. Among 525 Swedish men, marine fatty acids were associated with lower risk of prostate cancer death (events: 222; HR Q4 v. Q1: 0.5; 5% CI: 0.40, 0.87) and, among the men diagnosed with localized disease (46 events), myristic acid and shortchain saturated fatty acids were associated with higher risk of prostate cancer death (HR Q4 v Q1: 2.3; 5% CI: 1.06, 5.38 and HR Q4 v. Q1: 2.88; 5% CI: 1.24, 6.67, respectively).","[4.0, 3.0, 4.0, 3.0]",Medicine,train,3.5,news,http://www.sciencedaily.com/releases/2013/06/130610192948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-019-10570-w,Medicine_427,It has to link to Ran first in order to reach the cell membrane.,"In fact, the Ran association with RhoA prevents its ubiquitin-mediated proteasomal degradation through promoting RhoA localization to the PM and then its activation.","""In normal cells, RhoA can make its way directly to the cell membrane but in ovarian cancer cells it cannot. It has to link to Ran first in order to reach the cell membrane. ""In our study, we showed that in cancer cells where we inhibit the action of Ran, RhoA gets broken down.","In summary, this study provides an undescribed link between Ran and RhoA signaling that collectively contributes to enhanced ovarian cancer cell growth and invasiveness. In fact, the Ran association with RhoA prevents its ubiquitin-mediated proteasomal degradation through promoting RhoA localization to the PM and then its activation. The fact that ovarian cancer cell proliferation and invasion can be affected by disrupting the interaction between Ran and RhoA provides a rationale to develop advanced pharmacological compounds to prevent ovarian cancer cell progression.","[2.0, 2.0, 4.0, 2.0, 1.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=39652157590&p=1pl&v=1&x=iLAV7nt5Bd4yspqFvXSuQg
10.1038/s41467-018-05870-6,Medicine_43,"""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases.""",The regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic activity in obesity-associated sequelae.,"""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology. ""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases."" Novel Science

The scientists caution the research is early stage.","Notably, hepatic Ago2-deficiency improves glucose metabolism in conditions of insulin receptor antagonist treatment, high-fat diet challenge, and hepatic AMPKα1-deletion. The regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic activity in obesity-associated sequelae. Upon loading of Ago proteins with mature miRNAs produced by the endoribonuclease Dicer 18 , RISC represses the expression of targeted mRNA through RNA silencing .","[4.0, 4.0, 3.0, 4.0]",Medicine,train,3.75,news,http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A
10.1542/peds.2014-2707,Medicine_430,"While the reasons for the difference in sleep times is unclear, it could be due to housing quality, obesity, and conditions that disrupt sleep, as well as worrying about money, of course.","Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts born in the early 1990s, were more likely to report regular $7 hours of sleep compared with all other adolescents.","Despite the fact that the recommended amount of sleep for adolescents is nine hours, students from lower-income families and ethnic minorities did not report having more than seven hours of sleep a night. While the reasons for the difference in sleep times is unclear, it could be due to housing quality, obesity, and conditions that disrupt sleep, as well as worrying about money, of course. Interestingly, the study also found that students from middle and higher-income families who had parents that received a high school education regularly had more than seven hours of sleep per night.","Thus, these data indicate that adolescent sleep is declining across all age groups and major sociodemographic subgroups. Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts born in the early 1990s, were more likely to report regular $7 hours of sleep compared with all other adolescents. Third, we documented that girls are less likely to regularly report $7 hours of sleep and to feel they get adequate sleep, as are black/Hispanic adolescents and those in lower SES strata.","[5.0, 3.0, 2.0, 4.0, 5.0]",Medicine,train,3.8,news,http://www.inquisitr.com/1865139/rich-americans-sleep-better-at-night-than-poor-ones-study-finds/
10.1001/jamaoto.2018.1446,Medicine_431,">> RELATED: Hi-tech nose helps sniff out cancer, 16 other diseases by analyzing breath

After analyzing the results, they discovered that the ability to identify odors decreases with age, while phantom odor perception seems to improve with age.","In this cross-sectional study of 7417 adults, the prevalence of phantom odor perception was 6.5% (n = 534) and was greater among women, younger age groups, and those of lower socioeconomic position.",">> RELATED: Hi-tech nose helps sniff out cancer, 16 other diseases by analyzing breath

After analyzing the results, they discovered that the ability to identify odors decreases with age, while phantom odor perception seems to improve with age. Furthermore, they said that one in 15 Americans experience phantom odors. It was most prevalent among adults aged 40-60, and twice as many women as men reported the condition, particularly women under age 60.","Overall response rates for the interviewed sample were 72.6% in the 2011-2012 period and 71.0% in the 2013-2014 period. In this cross-sectional study of 7417 adults, the prevalence of phantom odor perception was 6.5% (n = 534) and was greater among women, younger age groups, and those of lower socioeconomic position. Phantom odor perception was more common among those with poorer health, a history of head injury, or dry mouth symptoms.","[3.0, 4.0, 2.0, 4.0]",Medicine,train,3.25,news,http://ct.moreover.com/?a=34841635020&p=1pl&v=1&x=HkVZeOeHcFcX4nK0eYTeTw
10.1038/srep03141,Medicine_432,"""Increases in Flickr photo counts with particular labels may reveal notable increases in attention to a particular issue, which in some cases may merit further investigation for policymakers.""","We find a striking correlation between the moving average of the normalized number of Hurricane Sandy related Flickr photos taken and the atmospheric pressure in New Jersey for Dt 5 24 hours (Kendall's tau 5 20.37, z 5 215.14, p , 0.001).","This probably doesn't come as a surprise to anyone familiar with social media. ""Increases in Flickr photo counts with particular labels may reveal notable increases in attention to a particular issue, which in some cases may merit further investigation for policymakers."" Through their analysis, scientists from the Warwick Business School found that as atmospheric pressure in New Jersey decreased - something that happens as a hurricane intensifies - so did the number of Hurricane Sandy-related Flickr uploads, and vice versa.","Visualization of the data reveals that the normalized number of photos taken increased continuously while ''Sandy'' was moving toward the coast of the United States ( Figure 1A ). We find a striking correlation between the moving average of the normalized number of Hurricane Sandy related Flickr photos taken and the atmospheric pressure in New Jersey for Dt 5 24 hours (Kendall's tau 5 20.37, z 5 215.14, p , 0.001). Notably, the time of landfall of Hurricane Sandy not only marks the time of lowest air pressure, but also the time at which the largest number of Flickr photos labeled with terms related to Hurricane Sandy were taken.","[4.0, 2.0, 4.0, 4.0]",Medicine,train,3.5,news,http://www.ibtimes.com/can-flickr-predict-natural-disasters-hurricane-sandy-created-digital-trace-when-photo-uploads-peaked
10.1016/j.jpsychires.2013.06.014,Medicine_433,"Dr Bilderbeck added: 'This was only a preliminary study, but nothing has been done like this before.","Participation in the yoga course significantly influenced positive affect as measured by the PANAS, F(1,86) ¼ 5.26, p ¼ 0.024.","'The suggestion is that yoga is helpful for these prisoners.' Dr Bilderbeck added: 'This was only a preliminary study, but nothing has been done like this before. Offering yoga sessions in prisons is cheap - much cheaper than other mental health interventions.","The average time that participants in the yoga group spent practising yoga (outside of class) did not differ significantly when compared to the time spent by the control group doing other forms of exercise (167.1 AE 48.4 min vs. 241.76 AE 27.0 min, respectively), t(75) ¼ À1.46, p ¼ 0.15. Participation in the yoga course significantly influenced positive affect as measured by the PANAS, F(1,86) ¼ 5.26, p ¼ 0.024. Exploration of simple effects demonstrated that participants did not differ in positive affect at baseline, F(1,86) < 1, but at Time 2 the yoga group reported significantly higher positive affect than the control group, F(1,86) ¼ 6.33, p ¼ 0.014.","[1.0, 1.0, 1.0, 3.0, 1.0]",Medicine,train,1.4,news,http://www.healthcanal.com/alternative-therapies/40699-prisoners-doing-yoga-may-see-psychological-benefits.html
10.1111/acer.12656,Medicine_434,"""We found that lower results on IQ tests in Swedish adolescent men are associated with a higher consumption of alcohol, measured in both terms of total intake and binge drinking,"" said Sjolund.","They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ.","""It could be the other way around for a minority of individuals, that is, when exposure to alcohol has led to cognitive impairment, but this is less likely to be found among young persons of course."" ""We found that lower results on IQ tests in Swedish adolescent men are associated with a higher consumption of alcohol, measured in both terms of total intake and binge drinking,"" said Sjolund. ""It may be that a higher IQ results in healthier lifestyle choices.","It should be noted that the authors report a skewed study population with regard to low socioeconomic position . They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ. A higher IQ was associated with being a rare, an occasional, and a moderate drinker, whereas there was a lower IQ for being a former drinker compared with being a lifetime abstainer.","[4.0, 4.0, 4.0, 5.0]",Medicine,train,4.25,news,http://www.sciencedaily.com/releases/2015/02/150220190744.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.cels.2017.12.013,Medicine_435,"As people pack on pounds or shed excess weight, they exhibit notable changes in their microbiome, cardiovascular system, immune system and levels of gene expression, the study found.",Extensive multi-omic profiling of the blood and microbiomes of healthy and insulin-resistant humans as they gain and lose weight reveals insights into the systemic impacts of weight gain.,"/ no comments

Medicine, Health Care Weight Flux Alters Molecular Profile,... As people pack on pounds or shed excess weight, they exhibit notable changes in their microbiome, cardiovascular system, immune system and levels of gene expression, the study found. ""Omics"" is equivalent to tacking on ""the study of"" to the names of areas of biological inquiry.","Graphical Abstract Highlights d Analysis of insulin-sensitive and -resistant individuals across multiple omes d We reveal molecular changes in the human body after modest short-term weight gain d Reversal of short-term weight gain eliminates negative molecular alterations d Open-access multi-omic resource for further bioinformatics developments Extensive multi-omic profiling of the blood and microbiomes of healthy and insulin-resistant humans as they gain and lose weight reveals insights into the systemic impacts of weight gain. As such, a more comprehensive molecular profiling approach may offer novel insights into the diversity of systemic responses to the increase in body fat stores.","[2.0, 4.0, 5.0, 4.0, 4.0]",Medicine,train,3.8,news,http://healthmedicinet.com/news/weight-flux-alters-molecular-profile-stanford-led-study-finds/
10.1001/jamapsychiatry.2013.2163,Medicine_436,The risks associated with maternal depression during pregnancy and maternal depression after pregnancy are clearly different.,Analyses found that maternal education moderated the effects of postnatal but not antenatal depression.,"In particular, the findings suggest that treating depression in pregnancy, irrespective of background, may be most effective."" The risks associated with maternal depression during pregnancy and maternal depression after pregnancy are clearly different. While maternal education can decrease the risks from postpartum depression, depression during pregnancy negatively affects children during early adulthood.","However, for more educated mothers, there was little association (odds ratio, 1.09; 95% CI, 0.88-1.36; P = .42). Analyses found that maternal education moderated the effects of postnatal but not antenatal depression. Paternal depression antenatally was not associated with offspring depression, while postnatally, paternal depression showed a similar pattern to maternal depression.","[4.0, 2.0, 4.0, 2.0]",Medicine,train,3.0,news,http://www.inquisitr.com/987314/maternal-depression-during-pregnancy-linked-to-depression-in-young-adults/
10.1073/pnas.1605782113,Medicine_438,Sound-meaning association biases evidenced across thousands of languages.,"Hence, the explanation for the observed prevalence of sound-meaning associations across the world has to be found elsewhere (49).","""Likely it has something to do with the human mind or brain, our ways of interacting, or signals we use when we learn or process language. That's a key question for future research."" Sound-meaning association biases evidenced across thousands of languages.","These results suggest that, although it is possible that the presence of signals in some families are symptomatic of a particularly pervasive cognate set, this is not the usual case. Hence, the explanation for the observed prevalence of sound-meaning associations across the world has to be found elsewhere (49). We have demonstrated that a substantial proportion of words in the basic vocabulary are biased to carry or to avoid specific sound segments, both across continents and linguistic lineages.","[5.0, 4.0, 3.0, 4.0, 4.0]",Medicine,train,4.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/UITWK-W4wO8/languages-use-same-sounds-common-objects-ideas-04185.html
10.1002/ece3.3060,Medicine_44,Distance between ponds and various landscape features could not fully explain the observed genetic differences.,found that no landscape surface described genetic differentiation demonstrably better than distance alone and our work expanding the number of ponds landscape surface described genetic differentiation demonstrably better than distance alone.,"DNA analysis showed that salamanders that breed in the fall move to new ponds less often than salamanders that breed in the spring. Distance between ponds and various landscape features could not fully explain the observed genetic differences. ""Even though some habitat features seemed to affect dispersal, we found that, for all four species, breeding season was a better predictor than habitat of the observed genetic differences,"" Burkhart says.",The support for a composite surface of TPI and distance from ravines explaining the genetic differentiation for A. annulatum and eastness describing genetic differentiation for A. maculatum extends previous work with A. annulatum and A. maculatum on this landscape. found that no landscape surface described genetic differentiation demonstrably better than distance alone and our work expanding the number of ponds landscape surface described genetic differentiation demonstrably better than distance alone. Our study differed from Bolded values indicate models with ΔAIC C < 2.0 in either the single surface or multiple surface optimizations.,"[2.0, 3.0, 4.0, 5.0]",Medicine,train,3.5,news,http://www.futurity.org/salamanders-breeding-1515412-2/
10.1038/s41588-018-0175-z,Medicine_440,"The video demonstrates that physical contact between the enhancer and the gene is necessary to activate transcription, the first step in reading the genetic instructions.",We show that sustained proximity of the enhancer to its target is required for activation.,"The video demonstrates that physical contact between the enhancer and the gene is necessary to activate transcription, the first step in reading the genetic instructions. The researchers also found that during transcription, the structure formed by the enhancer and gene becomes more compact, suggesting a change in the DNA in that region. advertisement

Given that there can be numerous genes between the enhancer and its target, it is remarkable that enhancers can reach the exact target at the right time for that gene to become active, the researchers said.","Even for a compact genome such as Drosophila melanogaster, at least 30% of enhancer-promoter interactions occur over 20 kb, and in many cases over intervening genes . We show that sustained proximity of the enhancer to its target is required for activation. Transcription in turn affects the three-dimensional topology as it enhances the temporal stability of the proximal conformation and is associated with further spatial compaction.","[1.0, 5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,news,http://ct.moreover.com/?a=34614782738&p=1pl&v=1&x=jOJzAOciM3ZzT6ZVS5rOkg
10.1038/ncomms16015,Medicine_441,"Professor Nick Wareham, director of the MRC Epidemiology Unit and a senior author of the study, noted: ""This work highlights the importance of muscle strength in the prevention of fractures and the complications which can often follow a fall.""","We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk.","Using the sixteen genetic variants identified for strength, the researchers were able to investigate the hypothesised causal link between strength and these adverse health outcomes. Their study found no evidence that lower strength causally increases risk of death or cardiovascular disease, but they did find evidence that higher muscular strength reduces risk of fracture, supporting the use of strength training interventions as a strategy to reduce risk of fractures. Professor Nick Wareham, director of the MRC Epidemiology Unit and a senior author of the study, noted: ""This work highlights the importance of muscle strength in the prevention of fractures and the complications which can often follow a fall.""","Grip strength is highly heritable (h 2 ¼ 30-65%) [10] . We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk. Multiple novel loci are associated with grip strength.","[2.0, 2.0, 4.0, 5.0, 3.0]",Medicine,train,3.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/QIOvIvcpAuc/
10.1073/pnas.1812786116,Medicine_442,"""While we found moderate effects at the national level, these results reflect mean differences,"" Karbownik said.","We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot differentiate in utero testosterone exposure from the postbirth socialization effects of being raised with a male co-twin.","""But whether we view those effects as 'positive' or 'negative' may be culturally dependent."" ""While we found moderate effects at the national level, these results reflect mean differences,"" Karbownik said. ""Not everyone will be affected in the same way, and some female twins may not be affected at all.","Consistent with some past studies, there was minimal evidence of any long-term impacts on males of exposure to a female co-twin (SI Appendix, Table S2 ). We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot differentiate in utero testosterone exposure from the postbirth socialization effects of being raised with a male co-twin. The coefficients in this more stringent subsample (n = 583) are similar to those in the full sample (Figs.","[1.0, 1.0, 1.0, 2.0, 2.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=38791064033&p=1pl&v=1&x=s_hKDbNKNwMBE8lWCXruqQ
10.3945/ajcn.113.066688,Medicine_443,"Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by how much messenger RNA -- the gene's instruction guide that tells a taste cell to build a specific receptor - their cells make.",We provide the first experimental evidence that mRNA expression amounts of the PAV allele of the TAS2R38 taste receptor gene correlate with sensory perception of bitterness and with dietary habits in humans.,"However, some perplexing pieces of the puzzle remained, as two people with exactly the same genetic makeup can still differ markedly regarding how bitter certain foods and liquids taste to them. Now, findings from Monell reveal that a person's sensitivity to bitter taste is shaped not only by which taste genes that person has, but also by how much messenger RNA -- the gene's instruction guide that tells a taste cell to build a specific receptor - their cells make. The findings add a new level of complexity to the understanding of the cellular mechanisms of taste perception, which may ultimately lend insight into individual differences in food preferences and dietary choices.","intensity, it was not combined with gene expression in a final model. We provide the first experimental evidence that mRNA expression amounts of the PAV allele of the TAS2R38 taste receptor gene correlate with sensory perception of bitterness and with dietary habits in humans. PAV-TAS2R38 expression was detected in the majority of PAV/AVI heterozygotes (61%), with substantial variation in expression that related to variations in psychophysical perception of known TAS2R38 ligands PROP and broccoli juice: the greater the gene expression, the greater the ratings of bitterness.","[4.0, 5.0, 5.0, 4.0, 3.0]",Medicine,train,4.2,news,http://www.sciencedaily.com/releases/2013/09/130911184403.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rsif.2019.0183,Medicine_444,"Those with trichromatic (normal) vision, on the other hand, were very good at breaking camouflage.","The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid desert dichromat historical accounts of the military value of dichromatic observers and contemporary theories for the maintenance of visual pigment polymorphisms in many New World monkey species .","Also, during testing with humans, they found that observers with dichromatic vision (color blindness) took longer to spot strongly colored animals. Those with trichromatic (normal) vision, on the other hand, were very good at breaking camouflage. They suggest their network could be a useful tool for better understanding the role color plays with animals living in the natural world.","Consequently this does not account for the difference between simulated dichromat and trichromat reaction times. The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid desert dichromat historical accounts of the military value of dichromatic observers and contemporary theories for the maintenance of visual pigment polymorphisms in many New World monkey species . This view seems to be confirmed by a brief survey of the literature.","[2.0, 5.0, 3.0, 5.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=39338408762&p=1pl&v=1&x=pliWAwUPbz0xbXd7c5wOLg
10.1038/s41598-018-29405-7,Medicine_445,"The team found that the greatest perception biases emerged when majority and minority groups were disproportionate in size, and when nodes of the same group were highly connected to each other.","Overall, despite the fact that in highly segregated networks the degree exponent and ranks of groups show similar behaviour, the ability of minority nodes to receive information from majority and vice versa decreases dramatically due to the split of the network.","Based on the position of an individual node within the network, the researchers predicted different perception biases would arise depending on two network properties: the relative sizes of the majority and minority groups, and their level of homophily (the extent to which like nodes connected to like). The team found that the greatest perception biases emerged when majority and minority groups were disproportionate in size, and when nodes of the same group were highly connected to each other. In these situations, individuals in both groups tended to overestimate their own group and underestimate the other.","In addition, information is transmitted faster among minority nodes in high homophily due to a smaller number of nodes and thus shorter transmission paths, resembling rumor spreading in a small village. Overall, despite the fact that in highly segregated networks the degree exponent and ranks of groups show similar behaviour, the ability of minority nodes to receive information from majority and vice versa decreases dramatically due to the split of the network. Note that the SI process in this setting can be thought as a random walk process for undirected graphs.","[2.0, 3.0, 2.0, 3.0, 4.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=39932111786&p=1pl&v=1&x=PKCnqR6uJrrrbBZhiSe8GQ
10.1016/j.ajhg.2018.10.007,Medicine_446,"""Our findings uncover, for the first time, a mechanism for the genesis of this abnormality and link the causal factors involved in recurrent molar pregnancies, miscarriages, and male and female infertility to mutations in three genes.""","In TOP6BL/C11orf80, we found in one woman (ID 10), with one miscarriage and two HMs, a 1-bp insertion, c.783dup (p.Glu262*) in a homozygous state (Figure 2A , Table S4 ).","Long-standing mystery

""Our findings add three new genes to the list of mutations leading to fetal loss and will allow for more DNA testing for patients in order to prevent the recurrence of molar pregnancies and provide better genetic counseling and management for couples,"" says lead author Rima Slim, an associate professor of human genetics and obstetrics and gynecology at McGill University and a researcher in the Child Health and Human Development Program at the Research Institute of the McGill University Health Centre. ""Our findings uncover, for the first time, a mechanism for the genesis of this abnormality and link the causal factors involved in recurrent molar pregnancies, miscarriages, and male and female infertility to mutations in three genes."" As reported in the American Journal of Human Genetics, researchers identified mutations in MEI1, TOP6BL/C11orf80, and REC114 in patients who had molar pregnancies without maternal chromosomes and recurrent miscarriages.","Using RT-PCR on total RNA from a LCL from the proband 880, we found that the invariant splice site mutation, c.1196þ1G>A, leads to a smaller cDNA fragment that corresponds to the skipping of exon 11 ( Figure 1D ) located in one of the two predicted Armadillo-type fold domains ( Figure 1E ). In TOP6BL/C11orf80, we found in one woman (ID 10), with one miscarriage and two HMs, a 1-bp insertion, c.783dup (p.Glu262*) in a homozygous state (Figure 2A , Table S4 ). The mutation segregated from both parents who were found to be heterozygous carriers.","[4.0, 2.0, 3.0, 4.0, 2.0]",Medicine,train,3.0,news,https://www.futurity.org/molar-pregnancy-miscarriage-genes-1917792/
10.1136/esmoopen-2017-000250,Medicine_447,"Cancer survivors naturally age faster than others who haven't had cancer, and are more likely to develop long-term health problems related to aging while they're still relatively young, the study authors said.","We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects.","Cancer survivors naturally age faster than others who haven't had cancer, and are more likely to develop long-term health problems related to aging while they're still relatively young, the study authors said. Survivors also are more likely to become frail as the years pass. Childhood cancer survivors' estimated life expectancy is 30 percent lower than that of the general population, and they are three to six times more likely to develop a second cancer, the researchers noted.","We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects. The direct effects of various chemotherapies and radiation on telomere length, senescent cells, epigenetic modifications and microRNA were found. Long-term follow-up of cancer survivors and research on prevention strategies should be pursued to increase the length and quality of life among the growing population of cancer survivors.","[5.0, 2.0, 4.0, 2.0, 4.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=32822546106&p=1pl&v=1&x=tiTNu_73pWjRQlX-YijqIg
10.1126/science.1244797,Medicine_448,"""In comparison, RAD data show an average GCR dose equivalent rate of 1.8 millisieverts per day on the journey to Mars, when RAD measured the radiation inside the spaceship.""",The RAD surface measurements provide a baseline for inferring the flux in these more shielded environments (by validating and anchoring transport models) and thus the foundation for understanding the limits to preservation of organic matter in the soil and rocks of Gale crater.,"""The RAD surface radiation data show an average GCR dose equivalent rate of 0.67 millisieverts per day from August 2012 to June 2013 on the Martian surface,"" said Hassler. ""In comparison, RAD data show an average GCR dose equivalent rate of 1.8 millisieverts per day on the journey to Mars, when RAD measured the radiation inside the spaceship."" According to RAD data, most mission radiation exposure will be during outbound and return travel, when the astronauts will be exposed to the radiation environment in interplanetary space, shielded only by the spacecraft itself.","The radiation environment on Mars may also play a key role in the chemical alteration of the regolith and martian rocks over geologic time scales, affecting the preservation of organics, including potential organic biosignatures of the ancient martian environment . The RAD surface measurements provide a baseline for inferring the flux in these more shielded environments (by validating and anchoring transport models) and thus the foundation for understanding the limits to preservation of organic matter in the soil and rocks of Gale crater. The GCR dose rate can be seen to vary between 180 and 225 microgray (mGy)/ day, owing to the combined effects of diurnal variations from atmospheric pressure changes, Mars seasonal variations at Gale crater, and heliospheric structure variability due to solar activity and rotation.","[3.0, 2.0, 3.0, 2.0]",Medicine,train,2.5,news,http://www.sciencedaily.com/releases/2013/12/131209181133.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41598-018-25573-8,Medicine_45,"""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor.","The color of liver, intestine and kidney was quite different.","In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered,"" write the investigators. ""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles.","5 left picture) . The color of liver, intestine and kidney was quite different. Kidney shape is altered and spleen shrank and could not be detected.","[1.0, 1.0, 2.0]",Medicine,train,1.3333333333333333,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1177/0146167214565055,Medicine_450,"Superstitions, by and large, apply to performance goals.","We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (contingent on external forces such as luck) will facilitate the achievement of learning goals, and will not use superstitious behavior to facilitate their achievement.","How well you do is up for debate. Superstitions, by and large, apply to performance goals. When we're at home studying, and the light from our desk lamp is illuminating all our missed math problems, we don't run to the dresser to fish out a pair of smelly socks -- we'd have no reason to.","Intrinsic motivation leads to a perception of internal (rather than external) locus of control , which is consistent with the idea that learning goals are judged internally-by oneself. We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (contingent on external forces such as luck) will facilitate the achievement of learning goals, and will not use superstitious behavior to facilitate their achievement. In Study 5, conditioning trials established positive or negative associations with several items.","[3.0, 5.0, 3.0, 2.0, 4.0]",Medicine,train,3.4,news,http://www.medicaldaily.com/superstition-comes-lacking-sense-control-science-behind-good-luck-charms-319098
10.1186/1742-9994-10-39,Medicine_451,"Dingoes and red foxes are temporarily suppressed, while feral cats and goannas are not affected, which suggests that careful planning of culls, around calving time to save livestock from attacks, should not in the long-term harm of other animals in the ecosystem.",Rarely did any of these occur for any mesopredator at any site.,"The culling of dingoes in Australia to protect livestock does not open the way for other predators to take their place finds research in BioMed Central's open access journal Frontiers in Zoology by the Invasive Animals CRC in Australia. Dingoes and red foxes are temporarily suppressed, while feral cats and goannas are not affected, which suggests that careful planning of culls, around calving time to save livestock from attacks, should not in the long-term harm of other animals in the ecosystem. This might then lead to a decrease in the numbers of smaller native prey normally eaten by these mesopredators, and ultimately a destruction of indigenous ecosystems.","If either fox, cat or goanna populations gained an overall benefit from lethal dingo control, then (1) overall mean mesopredator PTI should have been higher in baited areas, and/ or (2) mesopredator PTI values should have increased in baited areas following baiting, and/or (3) mesopredator PTI trends should have diverged from dingo PTI trends over time. Rarely did any of these occur for any mesopredator at any site. ), it is possible that dingo populations subjected to lethal control may also undergo demographic and social changes that might benefit mesopredator populations, such as the loss of experienced adults and an associated reduction in dingoes' ability to Table 4 for mean PTI values and sample sizes used in these analyses.","[1.0, 1.0, 2.0, 2.0]",Medicine,train,1.5,news,http://www.sciencedaily.com/releases/2013/07/130710114324.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s10071-013-0672-5,Medicine_453,"Apparently, chimpanzee mothers endow their offspring with important social skills.","Weighing these alternative explanations, however, we would argue that the deprivation of maternal care would be a more likely explanation of the presented results than the early trauma suffered by the orphaned chimpanzees.","Apparently, chimpanzee mothers endow their offspring with important social skills. It may not come as a surprise, but mother chimpanzees seem to be important for the development of social skills in young chimpanzees. ""Orphaned chimpanzees had more difficulties to successfully coordinate their social play interactions,"" says Edwin van Leeuwen from the Comparative Cognitive Anthropology Research Group at the Max Planck Institute for Psycholinguistics.","Finally, it might have been the case that early separation trauma intrinsically caused the orphaned chimpanzees to become less socially attuned, irrespective of the subsequent absence of maternal care. Weighing these alternative explanations, however, we would argue that the deprivation of maternal care would be a more likely explanation of the presented results than the early trauma suffered by the orphaned chimpanzees. The findings of the present study show the opposite pattern: the orphaned chimpanzees were both socially engaged (as reflected by the high frequency by which they initiated social play) and rather externally than internally oriented (as reflected by the aggressive outcomes of their social play bouts).","[3.0, 1.0, 4.0, 2.0, 4.0]",Medicine,train,2.8,news,http://www.sciencedaily.com/releases/2013/09/130906114300.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1542/peds.2013-3406,Medicine_454,"""However, association does not mean causation, and this is very important for the woman to understand.""","Adjusting, rather than restricting, for maternal mental health yielded similar findings.","""This study shows an association between the use of SSRIs and autism spectrum disorders,"" says Dr. Ariela Frieder of Montefiore Medical Center in New York. ""However, association does not mean causation, and this is very important for the woman to understand."" It is also important to contextualize how many cases of autism could be accounted for if a causal link to SSRI proved true.","The pattern was similar among boys in the anxiety/mood disorder subset, but with low precision (102 ASD, 29 DD, 50 TD). Adjusting, rather than restricting, for maternal mental health yielded similar findings. Results were similar, although attenuated.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.thedailybeast.com/articles/2014/04/17/new-study-shows-link-between-ssris-and-autism.html
10.1073/pnas.1606526113,Medicine_458,"For instance, it can take into account a whole range of factors that are decisive for hydrology, such as rain and snow volume, evaporation, groundwater and also the ways in which glaciers expand and experience changes in volume.",Modeling studies at a high spatiotemporal resolution and degree of process complexity are crucial to assess the impact of climate change on the hydrological balance of high-altitude catchments and to refine the projections of the coarser-scale models .,"New model also enables regional predictions

""What's new and unique about our model is that it can realistically illustrate many different processes,"" says Ragettli. For instance, it can take into account a whole range of factors that are decisive for hydrology, such as rain and snow volume, evaporation, groundwater and also the ways in which glaciers expand and experience changes in volume. This enables them to make precise predictions for how the water balance is likely to shift.","Given the multitude of control factors, often acting at relatively small scales, current projections of global glacier change models do not constrain the mechanisms underlying the variations in river flow from high-altitude catchments well . Modeling studies at a high spatiotemporal resolution and degree of process complexity are crucial to assess the impact of climate change on the hydrological balance of high-altitude catchments and to refine the projections of the coarser-scale models . Model construction and calibration benefited from extensive shortterm field campaigns, which allowed overcoming the problem of data scarcity typical of poorly accessible high-altitude regions.","[4.0, 4.0, 4.0, 4.0, 3.0]",Medicine,train,3.8,news,http://healthmedicinet.com/news/opposing-mountain-ranges/
10.1073/pnas.1407535111,Medicine_459,We find that there is some truth to this: lower expectations make it more likely that an outcome will exceed those expectations and have a positive impact on happiness.,"However, self-reported overall happiness did not increase between the beginning and the end of the experiment [initial happiness: 60 ± 18, final happiness: 54 ± 20 (mean ± SD), t(25)= −1.0, P = 0.33; Fig.","In real-world situations, the rewards associated with life decisions such as starting a new job or getting married are often not realised for a long time, and our results suggest expectations related to these decisions, good and bad, have a big effect on happiness. We find that there is some truth to this: lower expectations make it more likely that an outcome will exceed those expectations and have a positive impact on happiness. However, expectations also affect happiness even before we learn the outcome of a decision.","Prizes up to £3 were sufficient to elicit changes in happiness with root-mean-square differences between successive ratings of 17 ± 8 (mean ± SD, range 6-43). However, self-reported overall happiness did not increase between the beginning and the end of the experiment [initial happiness: 60 ± 18, final happiness: 54 ± 20 (mean ± SD), t(25)= −1.0, P = 0.33; Fig. The relationship between task earnings and the difference between initial and final happiness was not significant (P = 0.16, r 2 = 0.079).","[2.0, 4.0, 2.0, 1.0, 1.0]",Medicine,train,2.0,news,http://www.healthcanal.com/mental-health-behavior/53795-equation-to-predict-happiness.html
10.1001/jama.2018.20578,Medicine_46,"In other words, researchers wrote, approximately one in 200 people treated with aspirin would experience significant bleeding.","6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64% (5% CI, 0.35%-0.7%) for major bleeding.","Compared to those who didn't take aspirin, aspirin use was associated with a 43 percent increase of major bleeding events. In other words, researchers wrote, approximately one in 200 people treated with aspirin would experience significant bleeding. To prevent a single heart attack, stroke or cardiovascular death, approximately 250 patients needed to be treated with the drug for five years.","However, the use of cardiovascular risk scores tends to overestimate an individual's true risk, 32 with poor agreement between different cardiovascular risk calculators. 6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64% (5% CI, 0.35%-0.7%) for major bleeding. The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude.","[3.0, 1.0, 4.0, 4.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=38330617260&p=1pl&v=1&x=SFs6QnNOIxtCukPluYBeGg
10.1111/cdev.12344,Medicine_460,"Our study reveals some of the negative implications of higher rates of teachers' symptoms of depression for students.""","Teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement.","Our study reveals some of the negative implications of higher rates of teachers' symptoms of depression for students."" The students most vulnerable to the negative effects of their teachers' depression were those who were already struggling in math, suggesting that the children who needed to improve the most were less likely to be able to do so when their teachers were depressed. Students with weaker math scores made greater gains when they were in higher-quality classrooms with less depressed teachers.","This depended on students' fall mathematics scores; students who began the year with weaker math skills and were in classrooms where teachers reported more depressive symptoms achieved smaller gains than did peers whose teachers reported fewer symptoms. Teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement. The findings point to the importance of teachers' mental health, with implications for policy and practice.","[3.0, 4.0, 1.0, 5.0]",Medicine,train,4.0,news,http://psychcentral.com/news/2015/02/12/teachers-depression-linked-to-poor-student-performance/81153.html
10.1177/0141076815593403,Medicine_461,"If the program is successful, these rates should fall over time, indicating that mammography screening is contributing effectively to reducing breast cancer mortality.","Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death also applied to cancer cases diagnosed when screening (or absence of screening) was the same in both screening and control groups.","Early detection reduces the risk of being diagnosed with an advanced cancer that is often deadly. If the program is successful, these rates should fall over time, indicating that mammography screening is contributing effectively to reducing breast cancer mortality. Moreover, with increased screening, more rapid and more pronounced falls in breast cancer mortality would be expected in countries that implemented mammography screening program at end of the 1980s than in countries that implemented programs 10 to 15 years later.","The compensation argument invoked by Swedish trial investigators 6, is thus not tenable. Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death also applied to cancer cases diagnosed when screening (or absence of screening) was the same in both screening and control groups. Such result is compatible with an effect of being allocated to the screening or to the control group on the risk of breast cancer death (allocation effect), but not with an effect of mammography screening (screening effect) on that risk.","[2.0, 4.0, 1.0, 3.0, 5.0]",Medicine,train,4.0,news,http://www.oncologynurseadvisor.com/benefits-of-mammography-may-be-statistically-overestimated/article/428234/
10.1002/pon.4156,Medicine_462,"In the study, more physical activity was associated with higher levels of self-confidence, lower distress and less fatigue, which in turn is associated with lower levels of perceived memory impairment.","Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI.","The study will be published July 8 in the journal Psycho-Oncology. In the study, more physical activity was associated with higher levels of self-confidence, lower distress and less fatigue, which in turn is associated with lower levels of perceived memory impairment. ""We found moderate to vigorous physical activity actually benefits women psychologically and that, in turn, helps their memory,"" Phillips said.","Survivors who reported higher levels of distress also reported higher levels of fatigue (β = 0.63). Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI. Additionally, the indirect paths from physical activity to SMI via exercise self-efficacy and distress, exercise self-efficacy and fatigue and exercise selfefficacy, distress and fatigue were all significant.","[3.0, 3.0, 5.0, 1.0, 1.0]",Medicine,train,3.0,news,http://healthmedicinet.com/news/moderate-to-vigorous-physical-activity-linked-to-improved-memory-in-breast-cancer-survivors/
10.1038/s41541-019-0118-4,Medicine_463,"""We're excited by these findings, because they seem to suggest that we can use the body's own immune system to make antibodies against these tangles, and that these antibodies actually bind and clear these tau tangles,"" said Ph.D. student Nicole Maphis at UNM's Biomedical Sciences department in a press release.","Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be beneficial in preventing tau pathology and could be applicable to diverse human tauopathies, such as Alzheimer's disease (AD), frontotemporal dementia (FTD), traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE).","When the mice fed the vaccine were put in maze like test scenarios, they fared better than mice who had not received treatment. ""We're excited by these findings, because they seem to suggest that we can use the body's own immune system to make antibodies against these tangles, and that these antibodies actually bind and clear these tau tangles,"" said Ph.D. student Nicole Maphis at UNM's Biomedical Sciences department in a press release. Maphis studied the MRI scans and noted that the brains of the vaccinated mice had not shrunk.","Reduction in pathological consequences following this immunotherapy translated into improved cognitive function using well-established measurements of delay-dependent and spatial learning and memory tests. Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be beneficial in preventing tau pathology and could be applicable to diverse human tauopathies, such as Alzheimer's disease (AD), frontotemporal dementia (FTD), traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE). In one example, pTau peptide (MAPT 9-8 , pS6/ 4) formulated with an adjuvant (Adju-Phos), induced taureactive antibodies, reduced MC1 and PHF1 positive neurons in the brains of TgP301L mice and rescued cognitive function.","[2.0, 2.0, 3.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39458834280&p=1pl&v=1&x=a6UcobFlOESXjLG2kIvzhA
10.1126/science.1261498,Medicine_464,"""If we can use computational tricks to predict the host, we can explore that viral-host linkage.","Beyond core and pan metagenomic analyses, PCs also provide a metric for viral community diversity comparisons (Fig.","""None of these genomic features is really a smoking gun per se, but combining them led to a robust detection of 'new' viruses - viruses we did not have in the database, but can identify because they have capsid genes and a viral organization,"" he said. ""If we can use computational tricks to predict the host, we can explore that viral-host linkage. That's a really important part of the equation.""","Indeed, nichedifferentiation has been observed in viromes sampled across these oceanic zones in the POV data set (28), and similar findings were observed in the microbial metagenomic counterparts from the Tara Oceans Expedition (25). Beyond core and pan metagenomic analyses, PCs also provide a metric for viral community diversity comparisons (Fig. 3A and file S1 ) from which three trends emerge in the TOV data set.","[4.0, 1.0, 3.0, 1.0, 3.0]",Medicine,train,2.0,news,http://www.technology.org/2015/08/17/%e2%80%8bfishing-expedition-nets-nearly-tenfold-increase-number-sequenced-virus-genomes/
10.1038/s41467-018-04133-8,Medicine_465,The results of this study provide new insight into the channel function.,"It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement.","In the context of drug delivery, this platform is considered 'drug-agnostic,' which simply means the same membrane technology can be used for a wide spectrum of drugs, and just the size of the channel is what needs to be customized. The results of this study provide new insight into the channel function. Upon putting them to the test, however, they discovered intriguing, unexpected molecular behavior in these channels.","3 and Supplementary Fig. It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement. Figure 2b exhibits release curves of anionic cefazolin, (3-aminosalicylic acid in Supplementary Fig.","[4.0, 3.0, 5.0, 1.0, 4.0]",Medicine,train,4.0,news,http://healthmedicinet.com/news/discovery-will-impact-design-of-drug-delivery-systems-at-the-molecular-level/
10.1038/s41588-018-0135-7,Medicine_466,The study has also generated the first comprehensive database of which microbes are associated with which chemical metabolites in the gut.,"2b ), and one metabolite, phytanate, was significantly different between the oldest and youngest deciles (P = 5.0 × −3 ; Fig.",On the back of the study researchers have built a gut metabolome bank that can help other scientists engineer bespoke and ideal gut environments that efficiently process and distribute fat. The study has also generated the first comprehensive database of which microbes are associated with which chemical metabolites in the gut. This can help other scientists to understand how bacteria in the gut affect human health.,"However, a multivariate partial-least-squares discriminant analysis incorporating all the common 570 metabolites was able to distinguish the oldest decile (> 75 years) from the youngest decile (< 56 years) of the study population (area under the curve = 0.71, P = 6.8 × −6 ; Fig. 2b ), and one metabolite, phytanate, was significantly different between the oldest and youngest deciles (P = 5.0 × −3 ; Fig. These results suggest nonlinear associations between the fecal metabolome and age, in line with previous reports on the effects of age on the gut microbiome .","[2.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=34164034859&p=1pl&v=1&x=zrs5-TWfNa6KsyzWLpB7FQ
10.1126/sciadv.1400155,Medicine_467,"However, the findings also revealed that the markings of male and female birds have become less different over time, as the animals attempt to blend in with their surroundings to hide themselves from predators.","Plumage with more UV/blue/green reflectance (higher PC2) in both sexes was associated with larger body mass, sedentary behavior, semiprecocial young (that is, gulls with white UV-reflecting plumage), male parental care, and nesting in trees (table S2) .","However, the findings of the research team are the opposite. However, the findings also revealed that the markings of male and female birds have become less different over time, as the animals attempt to blend in with their surroundings to hide themselves from predators. The research found that natural selection, which includes factors relating to migration, breeding in certain subtropical locations and taking care of their young, is as strong as sexual selection in the evolution of the color of a bird's plumage/

""Although most studies of bird plumage focus on dichromatism, evolutionary change has most often led to similar, rather than different, plumage in males and females,"" the researchers wrote in their study, adding that it is behavior and ecology that is the main driving force behind the plumage color of both male and female birds and not their sexes.","Note that these are general characteristics, because some of these variables rarely co-occur (for example, only 5% of species had both altricial young and no male care). Plumage with more UV/blue/green reflectance (higher PC2) in both sexes was associated with larger body mass, sedentary behavior, semiprecocial young (that is, gulls with white UV-reflecting plumage), male parental care, and nesting in trees (table S2) . More red/orange reflectance (lower PC2) in the plumage was associated with smaller body mass, migratory behavior, altricial young, lack of male parental care, and nesting on the ground.","[3.0, 4.0, 2.0, 1.0, 2.0]",Medicine,train,2.4,news,http://www.techtimes.com/articles/43011/20150330/evolution-of-bird-plumage-color-also-affected-by-predation.htm
10.1088/2057-1739/aa83bf,Medicine_468,"Dr Torga said: ""The system allows us to carry out continuous observation of the interactions of multiple cell types at cell-by-cell resolution, and observe the development of drug resistance in the cancer cells in real time.",The engineered microenviron ment device allows at the quantitative study at the singlecell level of signaling dynamics and gene expres sion by monitoring in realtime the interactions of multiple cell types in response to each other as well as varying environmental conditions over time.,"The team's system acts as an 'evolution accelerator', allowing the study of key interactions between host cells and cancer cells, and their response to the drug, to be carried out in a much shorter timeframe. Dr Torga said: ""The system allows us to carry out continuous observation of the interactions of multiple cell types at cell-by-cell resolution, and observe the development of drug resistance in the cancer cells in real time. ""Significantly, our results show that in response to chemotherapy, cancer cells can become drug resistant in just 10 days.""","Population dynamics is qualitatively different from singlecell behaviors. The engineered microenviron ment device allows at the quantitative study at the singlecell level of signaling dynamics and gene expres sion by monitoring in realtime the interactions of multiple cell types in response to each other as well as varying environmental conditions over time. This technology is expected to work as a powerful in vitro model for cancer tumors, and provide a tool for pre clinical drug development and screening.","[4.0, 3.0, 1.0, 4.0, 2.0]",Medicine,train,2.8,news,http://healthmedicinet.com/news/cell-culture-system-could-offer-cancer-breakthrough/
10.1126/science.1261713,Medicine_469,I'll try to update this piece with a link when it becomes available.),Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit.,"(Zahnle has critical commentary on the new Curiosity results as well, but as of the time I'm writing this article, it wasn't yet linked from the Science website. I'll try to update this piece with a link when it becomes available.) That reactivity paradoxically is what makes its sudden coming and going mysterious.",(13) . Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit. The plume results (13) were questioned (22) on the basis of a possible misinterpretation from methane lines whose positions coincided with those of terrestrial isotopic 13 CH 4 lines.,"[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.thedailybeast.com/articles/2014/12/16/methane-on-mars-life-or-just-gas.html
10.1001/jama.2018.20578,Medicine_47,"Over the thousands of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events.","25 However, the 10-year myocardial infarction event rate (19.2%) justified its inclusion in the high-risk subgroup.","Now the picture is a little more clear. Over the thousands of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events. At the same time, a daily aspirin habit was associated with a 0.47 percent higher absolute risk of severe internal bleeding.","The estimated population 10-year risk of the primary composite cardiovascular outcome was less than 10% in 6 studies enrolling 112 566 participants (median, 6.8%; range, 2.6%-8.1%) 6, 23, 24, 26 and was at least 10% in 7 studies enrolling 50 383 participants (median, 12.7%; range, 10.2%-15.9%). 25 However, the 10-year myocardial infarction event rate (19.2%) justified its inclusion in the high-risk subgroup. In studies in which the risk of the cardiovascular outcome was low, aspirin use was associated with reductions in the primary composite cardiovascular outcome (HR, 0.87 [95% CrI, 0.79-0.95]; ARR, 0.34% [95% CI, 0.14%-0.52%]; NNT, 297) compared with no aspirin (Figure 2 ;e T a b l e3i nSupplement 2).","[2.0, 2.0, 1.0]",Medicine,train,1.6666666666666667,news,http://ct.moreover.com/?a=38333931091&p=1pl&v=1&x=RFNXfRDC7W6ykWiKhqzpYQ
10.1073/pnas.1318801111,Medicine_470,"According to Bergouignan, who has tried the experiment many times, this creates a very strong effect.",The experiments revealed two important findings.,"The out-of-body experience was heightened by the illusion of stick touching the students as they watch a different stick point at the camera from a similar angle. According to Bergouignan, who has tried the experiment many times, this creates a very strong effect. Bergouignan explained that since the student's location was temporarily transported out of their bodies, they had trouble accessing their memories of the events that happened a week later.","Taken together, these imaging results associate out-of-body-induced episodic memory impairment with altered hippocampal recruitment. The experiments revealed two important findings. First, the behavioral results showed that episodic encoding of life events requires perceiving the world from the first-person perspective centered on one's real body, and violations of this basic condition produced impaired episodic recall, indicative of fragmented encoding.","[1.0, 3.0, 1.0, 1.0, 2.0]",Medicine,train,1.6,news,http://www.hngn.com/articles/26248/20140312/brain-struggles-recalling-out-of-body-memories-study-finds.htm
10.1016/j.cub.2014.12.023,Medicine_472,"Dr Webb added: ""When we concentrate on those groups of animals and plants which are best known, and where estimates of extinction risk are likely to be most reliable, the difference between marine and non-marine species disappears.","We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ).","This assessment means that species have been checked against a list of criteria published by the International Union for the Conservation of Nature, a time-consuming process that has been completed for only three per cent of marine species, with no assessments at all in three quarters of the major groups of marine animals and plants. Dr Webb added: ""When we concentrate on those groups of animals and plants which are best known, and where estimates of extinction risk are likely to be most reliable, the difference between marine and non-marine species disappears. ""We ought to be more concerned about marine species.""","16.8% marine), and proportions of predicted total species numbers (10.0% non-marine cf. We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ). These contain 42.7% of all described and 98.8% of all assessed marine species and 25.5% of described and 96.9% of assessed non-marine species.","[3.0, 3.0, 3.0, 5.0, 2.0]",Medicine,train,3.2,news,http://www.sciencedaily.com/releases/2015/01/150129125544.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1126/scitranslmed.3006055,Medicine_473,"They found that all of these drugs were safe after six hours of treatment, but longer-term treatment of about four days caused the mitochondria to malfunction.","These findings are analogous to our previous work in bacteria, in which we showed that clinically relevant doses of bactericidal antibiotics induce a common oxidative damage pathway (4).","They found that all of these drugs were safe after six hours of treatment, but longer-term treatment of about four days caused the mitochondria to malfunction. Kalghatgi and Spina then did a series of biochemical tests, which showed that the same three antibiotics damaged the DNA, proteins and lipids of cultured human cells -- exactly what one would expect from oxidative stress. The results mean that ""doctors should only prescribe antibiotics when they're called for, and patients should only ask for antibiotics when they have a serious bacterial infection,"" Collins said.","Second, we demonstrate that these deleterious effects are produced by clinically relevant doses of bactericidal antibiotics, both in cell culture and in mice. These findings are analogous to our previous work in bacteria, in which we showed that clinically relevant doses of bactericidal antibiotics induce a common oxidative damage pathway (4). Identifying bactericidal antibiotics as a cause of ROS overproduction and mitochondrial dysfunction in mammalian cells provides a basis for developing therapeutic strategies that could help alleviate adverse side effects associated with antibiotics.","[4.0, 1.0, 1.0, 4.0, 2.0]",Medicine,train,2.0,news,http://www.healthcanal.com/immune-system/40496-dodging-antibiotic-side-effects.html
10.1098/rsbl.2013.0974,Medicine_474,"Chimpanzees can and do use these same muscle movements when making an angry face, but their facial expressions were not linked to the time they spent trying to get into the box.","Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we might expect human facial expressivity to exhibit some important differences from other primates.","The results showed that the longer the children persisted at trying to open the box, the more they displayed a ""determination face"" -- essentially, pressed-together lips and a raised chin, the sort of muscle motion that happens if you stick out your lower lip. Chimpanzees can and do use these same muscle movements when making an angry face, but their facial expressions were not linked to the time they spent trying to get into the box. They did not show any facial expressions of determination, like pressed-together lips, a raised chin or otherwise.","Overall, physical similarity of the main facial expression configurations, however, may obscure important differences in how facial expression is actually used. Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we might expect human facial expressivity to exhibit some important differences from other primates. The link between expression and emotion is not absolute , but in order for some level of honest communicative meaning to evolve, there must be an advantage to both sender and receiver .","[2.0, 3.0, 4.0, 3.0, 4.0]",Medicine,train,3.2,news,http://www.scientificamerican.com/article/game-face-evolved-as-plea-for-help/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fevolution+%28Topic%3A+Evolution%29
10.1098/rspb.2014.2449,Medicine_475,The team claim that the massive increase in Holopedium will have a major impact on the ecosystem and the jelly could also block drinking water filtration systems.,"Many environmental changes other than Ca decline influence zooplankton, though they are unlikely to be the dominant factor explaining the rise of Holopedium.",Holopedium only require one tenth of the calcium of Daphnia and their jelly coating also protects them from predators. The upsurge in Holopedium has led to the water becoming increasingly gelatinous. The team claim that the massive increase in Holopedium will have a major impact on the ecosystem and the jelly could also block drinking water filtration systems.,"Additional data on nutritional thresholds and phytoplankton community composition would help to test these explanations. Many environmental changes other than Ca decline influence zooplankton, though they are unlikely to be the dominant factor explaining the rise of Holopedium. For example, the SEM suggests that recent declines in hypolimnetic oxygen levels due to climate warming can promote abundances of Chaoborus, which prey more heavily on daphniids than Holopedium ('increasing predation' mechanism).","[3.0, 2.0, 3.0, 2.0, 3.0]",Medicine,train,2.6,news,http://www.scientificamerican.com/article/plankton-culprit-turns-clear-lakes-to-jelly/
10.1016/j.biopsych.2013.11.018,Medicine_477,"Senior author Dr. Matcheri Keshavan, a Professor at Harvard Medical School, describes their results: ""The main finding was that psychotic disorders are characterized by reduced folding of the cortex in key brain regions such as the cingulate cortex (a brain region involved in thinking and emotions).","Although the direct BP-SZ comparison yielded no significant results, these findings of disparate gyrification profiles relative to controls may lend some support for the divides between psychotic diagnoses such as schizophrenia, schizoaffective disorder, and psychotic bipolar disorder.","""The cortical folding pattern itself may not be so important, but the disturbances in connections between brain regions implicated by the changes in cortical folding could provide critical clues to deficits in the integrity of brain circuits that contribute to symptoms and functional impairment in schizophrenia,"" commented Dr. John Krystal, Editor of Biological Psychiatry. Senior author Dr. Matcheri Keshavan, a Professor at Harvard Medical School, describes their results: ""The main finding was that psychotic disorders are characterized by reduced folding of the cortex in key brain regions such as the cingulate cortex (a brain region involved in thinking and emotions). Reductions in cortical folding may reflect alterations in brain development early in life in these disorders.","Psychotic bipolar disorder patients had only one region of significant difference compared to controls. Although the direct BP-SZ comparison yielded no significant results, these findings of disparate gyrification profiles relative to controls may lend some support for the divides between psychotic diagnoses such as schizophrenia, schizoaffective disorder, and psychotic bipolar disorder. Particularly, the more widespread hypogyria in schizoaffective disorder and schizophrenia than in bipolar disorder suggests that hypogyria may accompany nonaffective psychosis more than primary affective psychosis.","[4.0, 1.0, 2.0, 2.0, 4.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2014/09/140911092915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41467-017-00618-0,Medicine_478,"The paper, with first author Dr Mian Bi and co-senior author Dr Ke, is the first to show a direct role of tau in brain damage after stroke.","Accordingly, treatment of primary neurons with bicuculline or KCl to increase synaptic glutamate levels and induce excitotoxic signaling 38 resulted in ERK phosphorylation and IEGs induction in tau +/+ but not tau −/− cells ( Fig.","Drug development in this space should consider stroke as a disease that you can treat by targeting tau,"" Dr Ke added. The paper, with first author Dr Mian Bi and co-senior author Dr Ke, is the first to show a direct role of tau in brain damage after stroke. It demonstrates profound protection from brain damage, of more than 90 per cent, in the absence of tau.","This is in line with a failure to activate ERK downstream of synaptic NMDARs, while ERK inhibition mediated by extra-synaptic NMDARs 36 remained intact in tau −/− neurons. Accordingly, treatment of primary neurons with bicuculline or KCl to increase synaptic glutamate levels and induce excitotoxic signaling 38 resulted in ERK phosphorylation and IEGs induction in tau +/+ but not tau −/− cells ( Fig. Significant ERK phosphorylation upon receptor-independent activation with forskolin in tau +/+ and tau −/− neurons suggests that the ERK signaling cascade per se is functional, but at a reduced level in tau −/− mice (Fig.","[2.0, 4.0, 2.0, 2.0, 1.0]",Medicine,train,2.2,news,http://healthmedicinet.com/news/study-offers-a-new-mindset-in-the-search-for-stroke-therapies/
10.1007/s10935-017-0491-6,Medicine_479,"Encouraging even small amounts of exercise is important, Bellettiere added, because of its compounding effect in people's lives: If they take the stairs early in the day, they may make similar healthy choices later in the day.",Our results and these recommended modifications to the built environment are consistent with the principles of behavior in that both prompts for behavior and contingencies of reinforcement increase stair use .,"""It's the first time this kind of effect has been shown at an airport."" Encouraging even small amounts of exercise is important, Bellettiere added, because of its compounding effect in people's lives: If they take the stairs early in the day, they may make similar healthy choices later in the day. Also, when people see others taking the stairs, they are more likely to do so themselves, creating a ripple effect.","This result led the CDC to recommend improved and aesthetically pleasing stairwells for all their facilities worldwide . Our results and these recommended modifications to the built environment are consistent with the principles of behavior in that both prompts for behavior and contingencies of reinforcement increase stair use . At the San Diego airport, for example, making the stairs wider, more visible, and easier to access than escalators may serve as prompts to increase stair use.","[3.0, 2.0, 4.0, 3.0, 3.0]",Medicine,train,3.0,news,http://healthmedicinet.com/news/making-healthier-decisions-step-by-step/
10.1210/en.2015-2036,Medicine_48,"The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis.","We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression.","The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis. The finding builds upon several previous studies suggesting that low levels of vitamin D not only increase a person's risk of developing breast cancer, but are also correlated with more-aggressive tumors and worse prognoses. Although the research was conducted primarily in mice and on mouse cells, the researchers found in a study of 34 breast cancer patients that levels of circulating vitamin D were inversely correlated with the expression levels of ID1 protein in their tumors, and they confirmed that a vitamin D metabolite directly controls the expression of the ID1 gene in a human breast cancer cell line.","Further, we discovered that attenuated vitamin D signaling due to Vdr ablation enhances tumor progression and, importantly, is sufficient to enable metastases, which are the primary cause of treatment failure and death for patients with BCa. We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression. Interestingly, Sherman et al found a tumor cell nonautonomous mechanism for VDR signaling to inhibit pancreatic ductal adenocarcinoma progression and Fernandez-Garcia et al found that calcitriol induces, rather than inhibits, Id1 expression in a colon carcinoma cell line.","[5.0, 2.0, 3.0, 3.0, 3.0]",Medicine,train,3.2,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1186/s13027-016-0049-x,Medicine_480,"If the former is true, Wang says simple antibiotics may prove useful or researchers can develop other therapeutic approaches for esophageal cancer utilizing genetic technology to target the P. gingivalis and ultimately destroy the cancer cells.","While the presence of P. gingivalis was not significantly associated with age, gender, or smoking history of the patients, the presence of P. gingivalis was positively related to differentiation, lymph node metastasis and the TNM stage of ESCC (p < 0.05).","According to Wang, there are two likely explanations: either ESCC cells are a preferred niche for P. gingivalis to thrive or the infection of P. gingivalis facilitates the development of esophageal cancer. If the former is true, Wang says simple antibiotics may prove useful or researchers can develop other therapeutic approaches for esophageal cancer utilizing genetic technology to target the P. gingivalis and ultimately destroy the cancer cells. aEURoeShould P. gingivalis prove to cause ESCC, the implications are enormous,aEUR Wang said.","If we set the samples with IHC scores more than 1 as P. gingivalis positive, the sensitivity and specificity of IHC would be 94.3 and 96.6 %, respectively (Kappa = 0.882; p < 0.001, Additional file 2: Table S1), showing excellence concordance between IHC and qRT-PCR for the detection of P. gingivalis infection in the cancerous tissues of ESCC patients. While the presence of P. gingivalis was not significantly associated with age, gender, or smoking history of the patients, the presence of P. gingivalis was positively related to differentiation, lymph node metastasis and the TNM stage of ESCC (p < 0.05). A positive immunohistochemical signal for P. gingivalis was 90 % in the poorly differentiated tissues, which was significantly higher than that of well or moderately differentiated samples (p < 0.05) ( Table 5) .","[3.0, 4.0, 2.0, 2.0, 4.0]",Medicine,train,3.0,news,http://healthmedicinet.com/news/p-gingivalis-could-be-a-novel-risk-factor-for-esophageal-cancer/
10.1016/j.ijlp.2009.01.002,Medicine_481,"Sociopaths, he suggested, are capable of feeling remorse or guilt.","Moreover, our findings do not support the hypothesis of an association between the interpersonal domain of psychopathy and greater cognitive abilities.","So, about all we can say is that around 1% of the male population would receive a score of 30"" on the extended exam or a score of 18 on a shorter version. Sociopaths, he suggested, are capable of feeling remorse or guilt. Lilienfeld said by email that the oft-cited 1 percent figure, rooted in research employing Hare's checklist, ""may be defensible, although it is also oversimplified.""","However, the negative association with the Affective factor was not confirmed by our study. Moreover, our findings do not support the hypothesis of an association between the interpersonal domain of psychopathy and greater cognitive abilities. It has to be considered, however, that our measure of intelligence was more simplistic than in other studies and that the lack of association might reflect measurement error.","[2.0, 1.0, 3.0, 2.0, 2.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=33688948919&p=1pl&v=1&x=BleRJIQwQoEXWJSTnroQ8g
10.1073/pnas.1803839115,Medicine_482,"Modeling and testing strategies that enable learning, attention, sensory processing and other functions in a computer can motivate and suggest new biological experiments that probe the mechanisms of intelligence both natural and artificial, the researchers said.","Humans and other advanced animals can rapidly learn new rules or tasks, in contrast to the thousands of data points usually required for ANNs to accurately perform new tasks.","The computational research also benefits the laboratory's original focus on better understanding the primate brain by recording its activity as animals learn and behave. Modeling and testing strategies that enable learning, attention, sensory processing and other functions in a computer can motivate and suggest new biological experiments that probe the mechanisms of intelligence both natural and artificial, the researchers said. ""Adding in this component of research to the lab has really opened a lot of doors in terms of allowing us to think about new kinds of problems, new kinds of neuroscience topics and problems that we normally can't really address using the experimental techniques currently available to us in the lab,"" Freedman said.","To our knowledge, these numbers of tasks are an order of magnitude greater compared to previously published work Nguyen et al., 2017; . Humans and other advanced animals can rapidly learn new rules or tasks, in contrast to the thousands of data points usually required for ANNs to accurately perform new tasks. This is because most new tasks are at least partially similar to tasks or contexts that have been previously encountered, and one can use past knowledge learned from these similar tasks to help learn the rules and contingencies of the new task.","[1.0, 4.0, 2.0, 3.0, 2.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=37417668602&p=1pl&v=1&x=xwt2GQA4KNm3ZCC-rb8usg
10.1080/00224499.2013.843148,Medicine_485,Teens want to discuss more than sex.,"Among this sexually active sample, 20 adolescents (38%) reported they had not used condoms every time they had sex in the past year, and 9 youth (17%) reported they had not discussed any sexual health topics with their dating partners.","On a personal note, when I speak with my own kids about sex, I am upfront and honest. Teens want to discuss more than sex. More than a third reported they wanted more guidance on how to have a mature relationship, handle breakups and how to not get hurt in a relationship.","Of the 603 7th and 8th graders that we sampled, 53 (8.8%; 29 girls, 24 boys) had engaged in sexual intercourse in the past year and 23 (3.8%; 12 girls, 11 boys) had had sex with two or more partners. Among this sexually active sample, 20 adolescents (38%) reported they had not used condoms every time they had sex in the past year, and 9 youth (17%) reported they had not discussed any sexual health topics with their dating partners. In addition, when asked about use of protection at first intercourse, 29 youth (55%) reported they had used a condom, and 8 of these adolescents (15%) indicated they had used both condoms and birth control pills the first time they had sex.","[2.0, 1.0, 3.0, 2.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34612105223&p=1pl&v=1&x=ZML-98OfCDRtz_WfrGcLMw
10.1016/j.amjmed.2013.04.026,Medicine_486,The findings reveal the importance of keeping up a higher level of physical activity--especially as we age.,"Compared with women with waist circumference <71 cm, the multivariate-adjusted RR for waist circumference >88 cm was 1.27 (95% CI 1.17, 1.38).",It turns out that hearing loss may be associated with obesity in women. The findings reveal the importance of keeping up a higher level of physical activity--especially as we age. Yet it turns out that there may now be ways to offset this hearing loss.,"Compared with women with BMI <25 kg/m 2 , the multivariateadjusted relative risk (RR) for women with BMI ≥ 40 was 1.25 (95% CI 1.14,1.37). Compared with women with waist circumference <71 cm, the multivariate-adjusted RR for waist circumference >88 cm was 1.27 (95% CI 1.17, 1.38). Higher physical activity was inversely related to risk; compared with women in the lowest quintile of physical activity, the multivariateadjusted RR for women in the highest quintile was 0.83 (95% CI 0.78,0.88).","[4.0, 2.0, 1.0, 2.0]",Medicine,train,2.25,news,http://www.scienceworldreport.com/articles/11159/20131125/obesity-linked-higher-risk-hearing-loss-women.htm
10.1111/papt.12095,Medicine_487,Increasing positive emotion can have a range of benefits including reducing attention to and experiences of threat.,"It would also be useful to evaluate this technique within a clinical group, where problems around accessing positive social memories and emotions will be more pronounced.","Increasing positive emotion can have a range of benefits including reducing attention to and experiences of threat. It was expected that the results would help to indicate when the social BMAC may be used most effectively in clinical settings. Social safeness increased

The study found that that safe/warm positive affect, relaxed positive affect and feelings of social safeness increased following the social BMAC, whilst negative affect decreased.","In future research, it would be helpful to have a comparison group who complete a relaxation imagery exercise to allow for the exploration of change brought about by the social BMAC above that of relaxation alone. It would also be useful to evaluate this technique within a clinical group, where problems around accessing positive social memories and emotions will be more pronounced. Nonetheless, the current study helps us to establish a proof-of-concept regarding the social BMAC.","[4.0, 5.0, 4.0, 1.0, 2.0]",Medicine,train,1.0,news,http://www.science20.com/news_articles/can_positive_memories_help_treat_mental_health_problems-170898
10.1038/s41467-018-05321-2,Medicine_488,"This finding proved that blocking SUMO proteases with new drugs could reduce inflammation, and in the future could treat inflammatory diseases.",Signal II triggers loss of sumoylation of NLRP3.,"They also found that blocking a further set of proteins called SUMO proteases - which themselves deactivate SUMOs - raised the levels of SUMO proteins. This finding proved that blocking SUMO proteases with new drugs could reduce inflammation, and in the future could treat inflammatory diseases. ""New drugs that block activation of inflammasomes could, in the future, be used to treat inflammatory diseases that involve aberrant activation of the immune response, including cancer.""","Taken together, these results indicate that NLRP3 is sumoylated in murine macrophages and human cells. Signal II triggers loss of sumoylation of NLRP3. Accordingly, we found that treatment with the bacterial toxin nigericin induced notable reduction of sumoylated NLRP3 ( Fig.","[1.0, 1.0, 1.0, 2.0, 2.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=37233930820&p=1pl&v=1&x=Aa6nBM2K5KAVpqdJ0YaxGg
10.1016/j.bbr.2018.07.009,Medicine_489,"Using animal models, Thanos found that regular aerobic exercise (one hour on a treadmill, five times a week) decreased stress-induced cocaine-seeking behavior.",5) .,"Using animal models, Thanos found that regular aerobic exercise (one hour on a treadmill, five times a week) decreased stress-induced cocaine-seeking behavior. Exercise also altered behavioral and physiological responses to stress. ""Our results suggest that regular aerobic exercise could be a useful strategy for relapse prevention, as part of a comprehensive treatment program for recovering cocaine abusers,"" Thanos says.","4) . 5) . A two way repeated measures ANOVA (between-subjects factor: exercise, within-subjects factor: stress) found no significant main effect of exercise treatment on corticosterone levels [F (1,22) costerone levels between sedentary and exercise rats (p > 0.05).","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34769125656&p=1pl&v=1&x=Q5cXML0nZW69IoP-wAIe9A
10.1038/s41589-018-0155-8,Medicine_49,"The team found that in adult mice, reducing ABHD12 activity with the inhibitor led to a rise in lyso-PS in immune cells called macrophages, as well as in brain tissue.",We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig.,"""This is a good example of how the study of a rare genetic disease can reveal a pathway that plays a key role in human biology,"" says study co-senior author Benjamin Cravatt, professor and chair of the Department of Chemical Physiology at Scripps Research. The team found that in adult mice, reducing ABHD12 activity with the inhibitor led to a rise in lyso-PS in immune cells called macrophages, as well as in brain tissue. The rise wasn't as great as that seen in the ABHD12-knockout mice, and even four weeks of treatment with the inhibitor appeared to cause only slight hearing defects -- nothing like the profound defects experienced by PHARC patients.","), which adopt a more macrophage-like cell state compared to undifferentiated THP-1 cells. We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig. 16 ) and alters lyso-PS and PS content in primary human macrophages, which showed elevations in both lyso-PS and 20:4 PS following 4 or 24 h treatment with DO264 (1 µ M), but not (S)-DO271 (1 µ M) ( Fig.","[4.0, 5.0, 1.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/d41586-018-04813-x,Medicine_491,These studies raise ethical questions whether the subject is an animal or an AI.,"Is there a point at which we should be concerned about the welfare of brain surrogates or chimaeras, such that assigning someone loosely akin to a guardian or decision-maker for the brain surrogate might be warranted, beyond the researchers involved?","The premiere of the second season of Westworld is a perfect time to ponder what makes us human. These studies raise ethical questions whether the subject is an animal or an AI. Yet as our models become more and more like the real thing (and for now, they are still quite a long way off), the problems with using them become so pronounced as to negate their utility--like Borges' map.","When people undergoing in vitro fertilization procedures choose to donate excess embryos to research, for instance, they are assured that these will not be used to create a baby. Is there a point at which we should be concerned about the welfare of brain surrogates or chimaeras, such that assigning someone loosely akin to a guardian or decision-maker for the brain surrogate might be warranted, beyond the researchers involved? Such an arrangement would be similar to the appointment of a guardian ad litem in custody disputes involving children in the United States (someone besides the parents who can represent the child's interests).","[4.0, 3.0, 3.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=33910842388&p=1pl&v=1&x=rFhRGsT2IZi6idGW_Ok3MA
10.1016/j.cell.2013.12.044,Medicine_493,"By relying on several factors, the insect has a better chance of a really juicy bite when given a choice of targets.",The role of mosquito vision in host-seeking and its interactions with odors warrants further investigation.,"It makes no sense for an animal (even a mosquito) to go bite anything that's warm if the blood thus harvested is nutritionally inadequate. By relying on several factors, the insect has a better chance of a really juicy bite when given a choice of targets. This research translates into practical information when designing chemical repellents to block mosquitoes from spreading malaria.","In addition, it is possible that diurnal patterns of flight periodicity in Ae. The role of mosquito vision in host-seeking and its interactions with odors warrants further investigation. Neither chemosensory input in isolation fully encodes the experience of the food or beverage, which may explain why humans with olfactory dysfunction report difficulties with enjoyment of food and wine .","[4.0, 2.0, 1.0, 3.0]",Medicine,train,2.5,news,http://guardianlv.com/2014/03/mosquitoes-select-their-targets-using-a-combination-of-sensory-cues/
10.1126/scitranslmed.aah4066,Medicine_494,"In contrast, a-synuclein did not stimulate the release of IL-1b from microglia obtained from NLRP3-knockout mice.","Inflammasome components are up-regulated, and activation occurs via NLRP3 in the 6-OHDA mouse model of PD.","... fibrillar a-synuclein mediates a delayed but robust activation of the inflammasome pathway in microglia,"" the team writes. In contrast, a-synuclein did not stimulate the release of IL-1b from microglia obtained from NLRP3-knockout mice. Their in vitro tests confirmed that MCC950 blocked mediators of microglial inflammasome activation by a-synuclein aggregates.","Inflammasome components are up-regulated in patients with PD. Inflammasome components are up-regulated, and activation occurs via NLRP3 in the 6-OHDA mouse model of PD. NLRP3 and ASC are up-regulated in the MitoPark mouse model of PD.","[1.0, 4.0, 2.0, 2.0, 2.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=37562808671&p=1pl&v=1&x=dc1ZI8yMrgwAVLaLhUUa7Q
10.1186/s40479-014-0023-4,Medicine_495,"Since dreaming mostly occurs during REM sleep, a complete lack of dreams could indicate that you arenat dropping into REM at all a which means that your sleep cycle is way out of whack.",Future studies should concentrate on ambulatory polysomnographic recordings to investigate sleep in natural environments to detect sleep and dream complaints in people with nightmares.,"Most people dream, even if they canat remember their dreams; whatas more, whether or not you remember your dreams actually doesnat say anything at all about the quality of your sleep. Since dreaming mostly occurs during REM sleep, a complete lack of dreams could indicate that you arenat dropping into REM at all a which means that your sleep cycle is way out of whack. If you have sleep apnea, this might be something you experience regularly.","Therefore, nightmares should be seen as a distinct sleep disorder with specific symptoms that needs specific treatment. Future studies should concentrate on ambulatory polysomnographic recordings to investigate sleep in natural environments to detect sleep and dream complaints in people with nightmares. Furthermore, the difference between nightmare distress and nightmare frequency should be regarded which may lead to new insights concerning objective sleep measures.","[4.0, 2.0, 2.0, 2.0]",Medicine,train,2.5,news,http://ct.moreover.com/?a=38986009666&p=1pl&v=1&x=B3U6MA4BMyLJIproaHuz1Q
10.1007/s12110-018-9323-5,Medicine_496,Scientists found that this hormonal and psychological shift made men more inclined to approach new potential partners.,"Moreover, the contrasting changes in testosterone in winners and losers significantly predicted the changes in SPMV, Child Involvement, and M-P Trade-off in the groups following the manipulation.","Scientists found that this hormonal and psychological shift made men more inclined to approach new potential partners. The body attempts to take advantage of this apparent status improvement by inducing chemical and consequently behavioural changes that promote a ""short-term"" approach to reproductive success, say the researchers. ""We found that a perceived shift in social status can cause male physiology to adapt by preparing to shift mating strategies to optimise reproductive success.""","Furthermore, winners exhibited a tendency toward increased sociosexuality, a measure of engaging in casual, uncommitted sexual relationships. Moreover, the contrasting changes in testosterone in winners and losers significantly predicted the changes in SPMV, Child Involvement, and M-P Trade-off in the groups following the manipulation. Both post-race testosterone and SPMV levels were significant correlates of the post-race outcome measures, whereas self-esteem was only correlated with men's likelihood of becoming involved with children, and consequently with the M-P Trade-off.","[3.0, 2.0, 3.0, 3.0, 3.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=34770036725&p=1pl&v=1&x=maeovqxLeM8k2R-pmDJURA
10.1016/j.ccell.2014.10.003,Medicine_497,"""Our study confirmed that the fusion gene ASPSCR1-TFE3 causes ASPS; it's the driver.""","Despite the already reported high expression of Hif1a and proangiogenic genes in ASPS, we demonstrated that these tumors lack frank hypoxia.","""That would be the ideal route to new and effective treatments. ""Our study confirmed that the fusion gene ASPSCR1-TFE3 causes ASPS; it's the driver."" Only 50 to 100 cases of ASPS are diagnosed in the United States each year, but this research bears on a fundamental question of cancer research: ""How does a cancer start?""","This model revealed an unusual anatomic distribution, which has implications with regard to cell of origin and the metabolic microenvironment. Despite the already reported high expression of Hif1a and proangiogenic genes in ASPS, we demonstrated that these tumors lack frank hypoxia. When provided exogenous administration of lactate, the tumors responded with enhanced proliferation and angiogenesis, suggesting that lactate, not hypoxia, contributes to this unique form of sarcomagenesis.","[3.0, 2.0, 2.0, 2.0, 2.0]",Medicine,train,2.2,news,http://www.sciencedaily.com/releases/2014/11/141126123921.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1745691613518075,Medicine_498,"Benefits of meta-synthesis for big data

Aside from the study results, Krizan said other researchers can benefit from using the meta-synthesis method.","To our knowledge, we are among the first in psychological science to use metasynthesis, and the present article could serve as a template for later researchers using this analytic technique.","""If people are evaluating themselves in terms of very specific criteria, they're going to have better self-insight because they are constrained by how to interpret the ability."" Benefits of meta-synthesis for big data

Aside from the study results, Krizan said other researchers can benefit from using the meta-synthesis method. Krizan says this type of analysis is a way to use the volume of big data that already exists.","Researchers in these situations may consider adopting a metasynthetic approach to derive a robust estimate of population effects. To our knowledge, we are among the first in psychological science to use metasynthesis, and the present article could serve as a template for later researchers using this analytic technique. There were several limitations to the use of metasynthesis for evaluating self-insight of ability across domains.","[2.0, 4.0, 3.0, 3.0, 5.0]",Medicine,train,3.4,news,http://www.newswise.com/articles/why-we-think-we-re-good-at-something-when-we-re-not
10.1186/s40575-015-0014-9,Medicine_499,"When making breeding decisions, genetic testing needs to be considered alongside health screening and family history.","Comparing historic photos of breed champions to their modern day kin, it is readily apparent that there has been selection towards exaggerated phenotypes among some breeds.","This approach has been successful in generating Dalmatians lacking a genetic defect that causes kidney stones, which is common in the breed. When making breeding decisions, genetic testing needs to be considered alongside health screening and family history. That will help to keep as much genetic diversity as possible in our pedigree dogs and, at the same time, reduce the prevalence of inherited diseases.""","None are more dependent on human intervention than breeds of extreme skull shapes and size. Comparing historic photos of breed champions to their modern day kin, it is readily apparent that there has been selection towards exaggerated phenotypes among some breeds. The ""stop"" (the angle formed by the rostrum and forehead) is more acute in today's St. Bernard and the ""Roman nose"" of the Bull Terrier angulates more ventrally than it did decades ago .","[2.0, 2.0, 2.0, 3.0, 1.0]",Medicine,train,2.0,news,http://www.sciencedaily.com/releases/2015/03/150304124137.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.jpeds.2017.10.028,Medicine_50,The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.,One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence.,"About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","9 These factors cut across various domains including affective (eg, emotion dysregulation, psychiatric disorder), cognitive (eg, attitudes toward women, beliefs about violence), demographic (eg, age, race, sex, sexual orientation, socioeconomic status), interpersonal (eg, relationship satisfaction, problem solving skills), contextual (eg, availability of weapon, drug/alcohol use), as well as distal factors (eg, history of child abuse, exposure to family violence). One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence. Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth.","[4.0, 4.0, 4.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1038/s41467-018-05031-9,Medicine_500,"In her study, Jone Michelena has already identified such a combination, which inhibits cancer cell proliferation to a significantly higher extent than the combination's individual components by themselves.","However, compared to microscopy-based measurements the sensitivity of both western blot and flow cytometry was extenuated and the lack of high-resolution cell images represents an additional limitation that precludes analyses of PARPi-induced changes at the subcellular level (see below).","Doing so can reveal which cell functions are needed for a certain drug to take effect.In addition, mechanisms of drug combinations can be analyzed in great detail. In her study, Jone Michelena has already identified such a combination, which inhibits cancer cell proliferation to a significantly higher extent than the combination's individual components by themselves. ""We hope that our approach will make the search for strategies to combat cancer even more efficient,"" says Matthias Altmeyer, head of the research group at the Department of Molecular Mechanisms of Disease at UZH.Jone Michelena, Aleksandra Lezaja, Federico Teloni, Thomas Schmid, Ralph Imhof, Matthias Altmeyer.","Also flow cytometry revealed olaparib-induced γH2AX signaling in S-phase cells (Supplementary Figure 1g ). However, compared to microscopy-based measurements the sensitivity of both western blot and flow cytometry was extenuated and the lack of high-resolution cell images represents an additional limitation that precludes analyses of PARPi-induced changes at the subcellular level (see below). All compounds resulted in clearly detectable S-phase specific γH2AX signaling after just 4 h of exposure, with niraparib having the strongest and PJ-34 the weakest effect (Fig.","[2.0, 2.0, 3.0, 1.0, 1.0]",Medicine,train,1.8,news,http://ct.moreover.com/?a=34516153762&p=1pl&v=1&x=eQWXvJNP_ZAMG9EbtqgrOA
10.1167/iovs.07-0804,Medicine_501,"If you're reading this, there's a good chance you spend much of your working day and leisure time staring at a computer screen.","Of all near-work activities, only the time spent reading for pleasure was independently associated with SER after adjustment for age, sex, ethnicity, and school type (P trend ϭ 0.02, Table 2 ).","If you're reading this, there's a good chance you spend much of your working day and leisure time staring at a computer screen. You probably spend less time thinking about what it's doing to your eyes. Many people are vaguely aware, though, that all that staring isn't great -- reflected in the dry, fatigued eyes they experience after a long day of work.","Less total near work was reported by the children of European Caucasian ethnicity than by those of East Asian ethnicity and by those attending public comprehensive schools than by those attending other school types (Table 1) . Of all near-work activities, only the time spent reading for pleasure was independently associated with SER after adjustment for age, sex, ethnicity, and school type (P trend ϭ 0.02, Table 2 ). In general, there was only a very weak correlation between SER and hours spent in near-work activities (correlation coefficient for all, r Յ Ϫ0.2; Table 3 ).","[1.0, 1.0, 1.0, 2.0, 2.0]",Medicine,train,1.4,news,http://www.vox.com/2014/8/5/5967487/computer-screen-eyesight-vision
10.1038/nature12775,Medicine_503,"advertisement

The third site, with a lower binding affinity, allows the calcium ions to move into the cell.",This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca 21 ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwisebinding process.,"This role is supported by the second site inside the pore. advertisement

The third site, with a lower binding affinity, allows the calcium ions to move into the cell. The flow of ions is accelerated by having these three binding sites in sequence.",Our results reveal interactions of hydrated Ca 21 with two high-affinity Ca 21 -binding sites followed by a third lower-affinity site that would coordinate Ca 21 as it moves inward. This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca 21 ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwisebinding process. The multi-ion selectivity filter of our Ca V Ab model establishes a structural framework for understanding the mechanisms of ion selectivity and conductance by vertebrate Ca V channels.,"[3.0, 3.0, 4.0, 4.0]",Medicine,train,3.5,news,http://www.sciencedaily.com/releases/2013/11/131124200508.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41419-018-0765-9,Medicine_504,"Reversal of the mutation restored mitochondrial function, as well as the skin and hair pathology.","Instead, follicles contained predominantly keratinaceous debris with only a few developing hair shafts which were fragmented and malformed.","The mitochondria of induced-mutation mice had reduced mitochondrial DNA content, altered mitochondrial gene expression, and instability of the large complexes in mitochondria that are involved in oxidative phosphorylation. Reversal of the mutation restored mitochondrial function, as well as the skin and hair pathology. This showed that mitochondria are reversible regulators of skin aging and loss of hair, an observation that Singh calls ""surprising.""","6d ) in mtDNA-depleter compared with wild-type mice, these follicles were aberrant and did not produce normal hair shafts in mtDNA-depleter mice. Instead, follicles contained predominantly keratinaceous debris with only a few developing hair shafts which were fragmented and malformed. Thus, alopecia was not due to loss of hair follicles or cessation of cycling; rather, the follicles were dysfunctional and could not produce normal hair shaft or completely lost this capability.","[2.0, 3.0, 3.0, 2.0, 2.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=34590725905&p=1pl&v=1&x=7f-YQHjEdaZi0GdLFEWbxQ
10.1093/molbev/mst211,Medicine_506,Their work suggests that a genetic mutation that makes certain people sensitive to the taste of a bitter compound appears to have been advantageous for certain human populations in Africa.,"Individuals with the common derived G-allele at position 665 had a lower mean salicin score compared with individuals with two common haplotypes, but the difference in mean score was not statistically significant (P = 0.382 in Central Africa; P = 0.425 in East Africa) (supplementary table S8, Supplementary Material online).","For this reason, the ability to sense bitterness likely played an important role in human evolution. Their work suggests that a genetic mutation that makes certain people sensitive to the taste of a bitter compound appears to have been advantageous for certain human populations in Africa. Yet the reason why this trait was selected may not have to do with just taste.","This analysis showed a significant difference in mean salicin sensitivity between genotypic classes (P = 0.035 in Central Africa; P = 0.033 in East Africa) (supplementary table S7, Supplementary Material online), with individuals possessing at least one derived T-allele having a higher mean score than individuals homozygous for the ancestral G-allele, indicating a functional difference between these polymorphisms (supplementary table S7, Supplementary Material online) consistent with in vitro analyses by . Individuals with the common derived G-allele at position 665 had a lower mean salicin score compared with individuals with two common haplotypes, but the difference in mean score was not statistically significant (P = 0.382 in Central Africa; P = 0.425 in East Africa) (supplementary table S8, Supplementary Material online). This univariate analysis also showed no significant difference (P = 0.933 in Central Africa; P = 0.589 in East Africa) in mean salicin score between groups with and without additional nonsynonymous variants (supplementary table S9, Supplementary Material online).","[3.0, 2.0, 1.0, 4.0, 4.0]",Medicine,train,2.8,news,http://www.sciencedaily.com/releases/2013/11/131111185522.htm
10.1098/rspb.2014.2120,Medicine_507,"The researchers found that when the seals put on enough fat to achieve neutral buoyancy, the number of strokes needed to complete a round-trip from bottom to surface was at its lowest.",Seals gradually became more buoyant as they increased their fat stores while foraging over the course of the migration.,"This means that she's negatively buoyant when she heads back out to sea and can sink into the deep water without swimming very hard. The researchers found that when the seals put on enough fat to achieve neutral buoyancy, the number of strokes needed to complete a round-trip from bottom to surface was at its lowest. ""At neutral buoyancy, they're able to spend more time foraging at depth because they're spending less energy moving up and down,"" said Costa.","At the start of each migration, all 14 seals were negatively buoyant, as indicated by the negative drift rate values (figure 1; electronic supplementary material, figure S3 ). Seals gradually became more buoyant as they increased their fat stores while foraging over the course of the migration. All seals were still negatively buoyant at the end of the short foraging migration, but five of seven seals became neutrally buoyant by the end of the recording period during the long foraging migration, as indicated by the drift rates being zero (i.e.","[5.0, 4.0, 3.0, 5.0, 4.0]",Medicine,train,4.2,news,http://www.scienceworldreport.com/articles/18617/20141105/benefits-being-fat-obese-elephant-seals-dive-better.htm
10.1073/pnas.1323342111,Medicine_508,"""When a fear face was incorrectly judged as happy, the neurons responded as if a happy face was correctly judged as happy -- in a sense, ""correctly"" representing the patient's incorrect judgment.",This suggests that amygdala neurons encode whole-face information and emotion independently.,"The team observed this also occurred when the neurons made and incorrect judgment about the face in question. ""When a fear face was incorrectly judged as happy, the neurons responded as if a happy face was correctly judged as happy -- in a sense, ""correctly"" representing the patient's incorrect judgment. When a happy face was incorrectly judged as a fear face, the neurons responded as if a fear face had been correctly judged as fear -- again, reinforcing the 'correctness' of the incorrect decision.","We found 3 out of 24 (12.5%) fear-selective cells and 5 out of 17 (29.4%) happyselective cells are also whole-face-selective, a ratio of whole-face cells similar to that found in the entire population (36 out of 185, 19.5%). This suggests that amygdala neurons encode whole-face information and emotion independently. We found that face information conveyed by the eyes, but not the mouth region, modulated emotion-selective neuronal responses.","[3.0, 4.0, 3.0, 3.0, 4.0]",Medicine,train,3.4,news,http://www.hngn.com/articles/35346/20140704/brain-region-responds-to-subjective-perceptions.htm
10.1186/1472-6920-12-82,Medicine_510,Such pay gap is of more concern given that both genders go through the same training and take similar risks.,"However, the significance of gender influence, stating the higher aspirations of women for general practice is not very strong (see table 4, Model 1: p = 0.046).","In USA, male physicians earned about 25% more than their female counterparts, widening the gap from 16% in 2000. Such pay gap is of more concern given that both genders go through the same training and take similar risks. Gap in leadership positions- Gender gap is more prevalent in leadership roles.","The finding that men aspire more to surgery specialties and women prefer more often general practice and nonsurgery specialties is consistent with previous research . However, the significance of gender influence, stating the higher aspirations of women for general practice is not very strong (see table 4, Model 1: p = 0.046). In separate analyses of different stages of education this gender influence even disappeared.","[3.0, 2.0, 3.0, 2.0, 2.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=37759049921&p=1pl&v=1&x=RXeUx8pnfSV9zoQ5zjpYTQ
10.1111/add.14393,Medicine_511,"""We know these harm reduction strategies are effective in preventing hepatitis C. We must improve our efforts to enhance strategies to prevent hepatitis C infection and reduce the number of new infections.""","The HCV viraemic prevalence was 60-80% in 10 countries, 40-< 60% in 38 countries and < 40% in 50 countries.","While this only represents 8.5 percent of all infections, there is a considerable further burden among people with a history of injecting drug use. ""We know these harm reduction strategies are effective in preventing hepatitis C. We must improve our efforts to enhance strategies to prevent hepatitis C infection and reduce the number of new infections."" The new research reveals that the greatest numbers of people with hepatitis C who have recently injected drugs live in Eastern Europe, East and Southeast Asia, and North America.","At the country level, there was very marked variation in the estimates of HCV viraemic prevalence between countries, ranging from 0.5% (UI = 0.0-1.4; Maldives) to 72.8% (UI = 68.8-76.7; Mauritius) ( Fig. The HCV viraemic prevalence was 60-80% in 10 countries, 40-< 60% in 38 countries and < 40% in 50 countries. The largest populations of people with recent injecting drug use living with HCV infection were in Russia (969 500; UI = 463 000-1 570 500), the United States (895 000; UI = 353 500-1 601 500), China (828 000; UI = 493 000-1 228 500) and Brazil (461 000, UI = 336 500-596 500) ( Fig.","[3.0, 3.0, 1.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34614481283&p=1pl&v=1&x=l9r6ZsooGbwi-xiv6r37nA
10.1089/trgh.2018.0014,Medicine_512,"This process revealed that, in this study sample, more time passed after undergoing gender-affirming surgery was associated with a lower likelihood of seeking mental health treatment.","Moreover, the DSM-5 clearly points to the existence of gender diverse populations who do not experience distress or impairment, prevalence studies then do not contribute to the validity of any tools determining GD.","Less than one-third received neither treatment. This process revealed that, in this study sample, more time passed after undergoing gender-affirming surgery was associated with a lower likelihood of seeking mental health treatment. That suggests that gender-affirming surgery boosts mental health over time, more so than hormone treatment or no treatment at all.","Moreover, if the intention of research is to understand links between biology and gender identity, it is methodologically weak to attempt to do so by looking solely at clinically referred populations for whom gender diversity is causing distress or impairment. Moreover, the DSM-5 clearly points to the existence of gender diverse populations who do not experience distress or impairment, prevalence studies then do not contribute to the validity of any tools determining GD. A large majority of articles did not make it clear whether ''clinically significant distress'' or social impairment had been established, or even assessed by a clinician or the researcher.","[3.0, 1.0, 3.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=40344614896&p=1pl&v=1&x=KM56ohmnQ-bIRGluHw3gKQ
10.1073/pnas.1409860111,Medicine_513,"Accurate or not, first impressions appear to stem from how a person looks.",First (Fig.,"Accurate or not, first impressions appear to stem from how a person looks. Even though it is not clear how accurate they are, these first impressions can influence our subsequent behavior (for example, judgments of competence based on facial images can predict election results). By combining these measures the model could explain more than half of the variation in human raters' social judgments of the same faces.","Note that our analysis suggests that social trait judgments are determined by multiple small contributions from different physical attributes, which means that it is impossible to unambiguously determine the contribution of each attribute (multicollinearity), although the correlations may serve to indicate relationships worthy of further investigation. First (Fig. Then (Fig.","[1.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.4,news,http://psychcentral.com/news/2014/07/29/facial-features-provide-first-impression/73005.html
10.1038/s41562-018-0366-8,Medicine_514,"And by providing evidence of the role of memory destabilization and reconsolidation in visual perceptual learning, the researchers offer insights into how the brain learns and refines new skills, keeping humans able to adapt in a changing world.",The similarity in the time-course changes in the E/I ratio and behavioural performance between reconsolidation and consolidation is in accordance with the hypothesis that these two processes have similar or some common underlying mechanisms.,"""This may explain why practice makes your skill and memory better, if you consider practice as a series of reactivations, increasing the level of plasticity again and again,"" Sasaki said. By showing that visual brain areas are highly excitable following memory reactivation, Sasaki and her colleagues shed light on how new information is incorporated into the memory. And by providing evidence of the role of memory destabilization and reconsolidation in visual perceptual learning, the researchers offer insights into how the brain learns and refines new skills, keeping humans able to adapt in a changing world.","First, although it has been controversial whether reactivation and reconsolidation of skill learning occurs in humans, our results show that reactivation and reconsolidation indeed occur in humans with VPL, a type of procedural learning. The similarity in the time-course changes in the E/I ratio and behavioural performance between reconsolidation and consolidation is in accordance with the hypothesis that these two processes have similar or some common underlying mechanisms. Thus, the E/I ratio decreases from high after the end of training or reactivation to baseline levels 3.5 hour later, thereby reflecting that both consolidation and reconsolidation are associated with decreases in the degree of plasticity.","[3.0, 3.0, 1.0, 2.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34502600282&p=1pl&v=1&x=LB8CER237X2pdI0qQt-rJg
10.1093/aje/kwu128,Medicine_515,"The compound result of both effects is that total mortality rises in expansions and falls in recessions.""","An increased hazard of death for nonwhites (for instance, by 26%; hazard ratio = 1.26 in model M1, Table 1 ) is observed across models (Tables 2-4 ), but the increase in the hazard, though always significant, ranges widely from 25% (Table 1, model M3) to 72% (Table 3, model M1LE) .","Compared with the increase in the risk of death among the unemployed, the decrease of the mortality risk associated with a weakening economy is small, but the benefit spreads across the entire adult population. The compound result of both effects is that total mortality rises in expansions and falls in recessions."" While this investigation did not cover the potential causes for these phenomena, the authors suggest that the increase in the risk of death associated with individual joblessness may be related to stress and depression, which often lead to substance abuse and other harmful behaviors.","Females have a significantly lower hazard of death. An increased hazard of death for nonwhites (for instance, by 26%; hazard ratio = 1.26 in model M1, Table 1 ) is observed across models (Tables 2-4 ), but the increase in the hazard, though always significant, ranges widely from 25% (Table 1, model M3) to 72% (Table 3, model M1LE) . Compared with nonmarried persons, married persons have a significantly reduced hazard of death-for instance, by 36% (i.e., 1 − 0.64 = 0.36) in model M1 (Table 1) .","[5.0, 3.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.healthcanal.com/public-health-safety/53473-losing-your-job-could-kill-you-but-recessions-could-be-good-for-your-health.html
10.1177/0956797614534694,Medicine_516,But it turns out the impact of sleeplessness goes deeper than a double espresso or two can solve.,"Planned comparisons revealed that in the morning-encoding condition, the false memory rate was significantly higher in the sleep-deprived group than in the rested group, t(51) = 2.01, p = .04 (two-tailed), Cohen's d = 0.56.","Anyone who's succumbed to a late-night Netflix marathon, only to stumble into work at 8 a.m. the next day, will vouch for the effect a lack of sleep can have on your brain function. But it turns out the impact of sleeplessness goes deeper than a double espresso or two can solve. That might be problematic enough if you're working in an office, for example, and you lose your focus after the phone rings.","However, there was a significant interaction between the factors, F(1, 99) = 4.52, p = .04. Planned comparisons revealed that in the morning-encoding condition, the false memory rate was significantly higher in the sleep-deprived group than in the rested group, t(51) = 2.01, p = .04 (two-tailed), Cohen's d = 0.56. However, in the evening-encoding condition, there was no significant difference in the false memory rate between sleep-deprived and rested participants, t(52) = 0.98, p = .33 (Fig.","[3.0, 2.0, 2.0, 2.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=37283282830&p=1pl&v=1&x=IqAMjFQanJyiIcdckYqgcw
10.1017/ice.2014.2,Medicine_517,"Risk for person-to-person transmission in A H7N9 is lower compared to other viruses including certain influenza strains, but some cases were identified as being spread between relatives.",Hand hygiene compliance demonstrated an increase in all clinical departments from 23% (2007 baseline) to 66% (2010) and to 75% (2013).,"""Despite the delay in airborne precaution implementation, we suspect that high hand hygiene compliance, as a result of continuous implementation of proactive control measures against various viruses and multidrug-resistant organisms, protected frontline healthcare workers against many challenges of emerging infectious diseases."" Risk for person-to-person transmission in A H7N9 is lower compared to other viruses including certain influenza strains, but some cases were identified as being spread between relatives. During the study period, 126 of 163,456 admitted patients were tested for the strain and two cases tested positive for A H7N9 influenza.","The pathogenicity of influenza A H7N9 appeared to be lower than that of HN1, but the former was capable of replicating in the upper and lower respiratory tract. Hand hygiene compliance demonstrated an increase in all clinical departments from 23% (2007 baseline) to 66% (2010) and to 75% (2013). The first case of influenza A H7N9 was in a 36-year-old Indonesian woman.","[1.0, 1.0, 1.0, 1.0, 2.0]",Medicine,train,1.2,news,http://www.healthcanal.com/infections/58819-infection-control-preparedness-measures-control-avian-flu-in-hong-kong-hospital.html
10.1002/cbic.201300796,Medicine_518,"The new system, described in the March 21st issue of journal ChemBioChem, could have a major impact on peptide drug development, says Bradley Pentelute, an assistant professor of chemistry and leader of the research team.","During our studies with ACP(65-74), we observed no decrease in the Val deletion peptide after double coupling Val and double deprotecting the preceding Gln, and these results are consistent with our experience optimizing the fragments of B. a. RNAse and the DARPin.","The new system, described in the March 21st issue of journal ChemBioChem, could have a major impact on peptide drug development, says Bradley Pentelute, an assistant professor of chemistry and leader of the research team. ""Because you can get these really fast now, you can start to do things you couldn't do before."" Using this approach, each amino acid addition takes only a few minutes, and an entire peptide can be assembled in little more than an hour.","Fourth, high quality peptides can be obtained quickly without double coupling, double deprotection, or colorimetric tests of coupling efficiency. During our studies with ACP(65-74), we observed no decrease in the Val deletion peptide after double coupling Val and double deprotecting the preceding Gln, and these results are consistent with our experience optimizing the fragments of B. a. RNAse and the DARPin. Finally, automation of this system enables faster cycle times, in contrast to the often slow automation of batch synthesis.","[1.0, 1.0, 2.0, 2.0, 1.0]",Medicine,train,1.4,news,http://www.sciencedaily.com/releases/2014/03/140319085543.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1146/annurev.psych.60.110707.163514,Medicine_519,"Rosenbaum, who was not a part of this research, tells Inverse that this study adds to a growing realization that gorilla social structures are more complex than we previously realized.","It draws on many of the same brain structures involved in perception, cognition, and behavior more generally, but specialization may be evident at the level of neural processing as well (see sidebar Face Processing and Modularity).","From the lens of human experience, it would be easy (and likely accurate) to call the latter group friends. Rosenbaum, who was not a part of this research, tells Inverse that this study adds to a growing realization that gorilla social structures are more complex than we previously realized. ""It would almost be more surprising if these were simply random interactions.""","Although many open questions remain, several of them linked to technical issues in measurement and analysis (see sidebar Future Challenges), it seems clear that human social cognition is both special and ubiquitous. It draws on many of the same brain structures involved in perception, cognition, and behavior more generally, but specialization may be evident at the level of neural processing as well (see sidebar Face Processing and Modularity). Three prominent differences discussed above are: the ability to shift one's conscious experience to places and times outside the here-and-now, and into the viewpoint of another mind (Buckner & Carroll 2006 ; the association of our evaluation of others with strong moral emotions that motivate particular aspects of social behavior, such as altruistic punishment (Fehr & Gaechter 2002) ; and the ability to use these abilities flexibly as a function of context, across considerable time intervals, and with the","[2.0, 1.0, 1.0, 2.0, 4.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39734684164&p=1pl&v=1&x=0ozGmWfzlQQwnUcL442DSg
10.1038/s41598-018-29793-w,Medicine_52,Each nasal microbiota type had a characteristic inflammatory response and viral load profile.,The results indicate that nasal microbiota has a role in the presentation of viral upper respiratory illness symptoms.,"The study team found that the baseline nasal microbiota samples divided into six types named after predominant bacterial genera: (1) Staphylococcus, (2) Corynebacterium/Alloiococcus, (3) Moraxella, (4) Haemophilus, (5) Pseudomonadaceae/Mixed, and (6) Mixed. Each nasal microbiota type had a characteristic inflammatory response and viral load profile. In general, subjects having Staphyloccocus, and Corynebacterium/Alloiococcus types had lower inflammatory responses and Pseudomonadaceae/Mixed type had lower viral load than other types.","The individual symptoms sneezing, plugged nose, and cough followed a similar pattern. The results indicate that nasal microbiota has a role in the presentation of viral upper respiratory illness symptoms. It has been shown that the severity of illness is modestly correlated with the innate inflammatory CXCL8 and CXCL10 response to the virus 33 , however the nasal lavage concentrations of these cytokines were similar between the clusters.","[5.0, 4.0, 3.0, 2.0, 4.0]",Medicine,train,3.6,news,http://ct.moreover.com/?a=37212363335&p=1pl&v=1&x=sLcdfRtU-o1Jl6n2DiKDzQ
10.1073/pnas.1422096112,Medicine_520,"""Defining biomarkers like this epigenetic tag associated with the oxytocin receptor may help us to predict future social developmental problems and inform interventions for those with social deficits,"" said co-author Jessica J. Connelly, a U.Va.",Analyses using a left amygdala seed region revealed no significant voxels.,"assistant professor of psychology, individuals with lower DNA methylation show diminished brain response to angry and fearful faces and greater communication between brain regions important for regulating emotion. ""Defining biomarkers like this epigenetic tag associated with the oxytocin receptor may help us to predict future social developmental problems and inform interventions for those with social deficits,"" said co-author Jessica J. Connelly, a U.Va. ""While our findings certainly have clinical implications, we show that even in a healthy population these markers are variable and may partially explain what makes each of us unique in how we respond in social situations,"" said the study's lead author Meghan Puglia, a Ph.D. candidate in psychology at U.Va.","S6 and S7) identified similar regions with the same pattern of activation. Analyses using a left amygdala seed region revealed no significant voxels. Using an imaging epigenetic approach, we provide evidence that a functional epigenetic modification within OXTR predicts individual variability in neural response to negative social stimuli.","[1.0, 1.0, 2.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.newswise.com/articles/u-va-team-finds-molecular-tag-that-explains-differences-in-brain-s-response-to-anger-fear
10.1073/pnas.1410186112,Medicine_521,But McIntyre said some of the findings were not entirely expected.,"In the Sierra Nevada, increases of small trees of 63% and declines of large trees of 20% were found in resurveyed plots .","There is indeed a general pattern across the entire state: large trees are in decline, and even though they are known to suffer disproportionate mortality rates in times of drought, the report describes the decline as ""striking."" But McIntyre said some of the findings were not entirely expected. ""What was somewhat surprising is that we detected a signal that the steepest declines in large trees were in areas where our models suggest that water stress for plants has increased the most.","The differences in forest structure between the contemporary and historical datasets are also consistent with results of smaller studies that attempted to relocate and resurvey VTM plots. In the Sierra Nevada, increases of small trees of 63% and declines of large trees of 20% were found in resurveyed plots . Similarly, a 79% increase in tree density was found in the Transverse ranges of southern California, attributed to fire suppression .","[1.0, 2.0, 1.0, 1.0, 4.0]",Medicine,train,1.8,news,http://www.theepochtimes.com/n3/1211310-changing-california-forests-may-help-us-prepare-for-the-future/
10.1037/a0014755,Medicine_522,"If anything, I think this is advice for parents of boys, to make sure that their boys have female friends growing up.","An important topic for future studies will be to further examine factors that lead to changes in suppression, including both features of the environment that may affect all individuals similarly and construal processes that may vary from one individual to the next.","Be friends with women, and that should really start when you're kids. If anything, I think this is advice for parents of boys, to make sure that their boys have female friends growing up. And once you have the groundwork for thinking of girls as equals, you can't just shift that.""","Variance in the dynamic component of suppression may reflect differences in how the transition was construed-as a traumatic separation by some and as an exciting social opportunity by others. An important topic for future studies will be to further examine factors that lead to changes in suppression, including both features of the environment that may affect all individuals similarly and construal processes that may vary from one individual to the next. Although we did not reassess suppression at the end of the fall term, indirect evidence suggests that changes in suppression may have endured.","[2.0, 2.0, 2.0, 3.0, 3.0]",Medicine,train,2.4,news,http://ct.moreover.com/?a=37631861006&p=1pl&v=1&x=MfBpuiejaIC9ZaCTBUlhMg
10.1016/j.biopsych.2010.02.005,Medicine_523,That's a lot to choose from.,"Pearson correlations indicated that OT was unrelated to demographic variables, including parent age, height, weight, smoking, use of medications, and time of last meal.","That's a lot to choose from. After the vole study, interest in the nine-amino acid peptide started to rise. It is not all marketing and placebos, however.","Figure 1 illustrates frequency distributions of OT levels in mothers and fathers during the first and second visits. Pearson correlations indicated that OT was unrelated to demographic variables, including parent age, height, weight, smoking, use of medications, and time of last meal. In addition, maternal OT was not related to menstrual cycle phase, contra- ceptive intake, mode of delivery (vaginal vs. caesarean section), feeding style (breastfeeding vs. bottle feeding), postpartum interval (weeks from birth to date of blood draw), or the interval from prior breastfeeding.","[3.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.8,news,http://www.scientificamerican.com/article/fact-or-fiction-oxytocin-is-the-love-hormone/
10.1126/scitranslmed.aaw2064,Medicine_527,"Although the work is still at an early stage, the findings open a ""realistic path"" that tests the links between pre-existing active lifestyle and subsequent recovery from a spinal injury, and possibly paves the way for clinical trials in human patients, say researchers at Imperial College London, led by the Dr. Simone Di Giovanni.","Parameters that correlated with improved recovery included reduced paw dragging, increased step height, and more frequent plantar steps with weight bearing (Fig.","This finding explains why people who have led an ""active lifestyle"" recover more after spinal cord injury than those with ""less active"" lifestyles. Although the work is still at an early stage, the findings open a ""realistic path"" that tests the links between pre-existing active lifestyle and subsequent recovery from a spinal injury, and possibly paves the way for clinical trials in human patients, say researchers at Imperial College London, led by the Dr. Simone Di Giovanni. ""We have shown that environmental enrichment, how housing the mice in a larger cage than usual, with other mice, with more toys, tunnels, swings, wheels, etc., increases the activity of the neurons.","PC1 captured the extent of the recovery, showing that CSP-TTK21 significantly (P = 0.0002) improved locomotor performance compared to CSPtreated rats. Parameters that correlated with improved recovery included reduced paw dragging, increased step height, and more frequent plantar steps with weight bearing (Fig. The number of footfalls occurring during locomotion across a horizontal ladder also decreased ( fig.","[3.0, 1.0, 1.0, 2.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=38965485737&p=1pl&v=1&x=YmKptu5RU9Zpxjvh34QP3Q
10.1093/asj/sjw089,Medicine_528,"However, a bazooka is not self-navigating.",This 49-year-old man is a poor candidate for leg hair extraction because of complete hair loss in most areas.,"With the Dr.UGraft Revolution Console and Nurture handpiece, the wait is finally over. However, a bazooka is not self-navigating. I prefer the term Tomahawk which is a self-guiding missile.""","The author has observed that following scoring by the UPunch Rotor, a variable percentage of grafts is completely Figure 3 . This 49-year-old man is a poor candidate for leg hair extraction because of complete hair loss in most areas. In the areas with hair, the hair is also vellous-looking with densities below 8 per cm 2 .","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=37347525609&p=1pl&v=1&x=3KFR7iLlfn28dZzIHuWgYQ
10.1063/1.4913758,Medicine_529,"The team's research sets up a framework by which future hillslope-soil models can be analyzed to predict the worst possible rain pattern that could lead the hillslope to flood, Curtu noted.","In fact, during this day the percentage of users tweeting from Venezuela (≈ 20%) was very low in comparison to the rest of the days (average around > 80%).","""In this case, by using physical parameters to describe a realistic hillslope, we found a pattern of precipitation that yields the greatest -- most amplified -- runoff coefficient, which determines the manner and how fast water will reach the river link."" The team's research sets up a framework by which future hillslope-soil models can be analyzed to predict the worst possible rain pattern that could lead the hillslope to flood, Curtu noted. This can be used to predict the extent of flooding possibilities based on predicted rain patterns.","Besides a large amount of users from all around the globe joined to the conversation, making the topic international, rather than local from Venezuela. In fact, during this day the percentage of users tweeting from Venezuela (≈ 20%) was very low in comparison to the rest of the days (average around > 80%). Hence, our set of Venezuelan elite were not capable of polarizing this majority of worldwide users.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.sciencedaily.com/releases/2015/03/150310123111.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41598-018-25573-8,Medicine_53,"These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.""","Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor.","Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer."" ""We were surprised when the tumor was formed in three days,"" notes Dr. Tamanoi.","Furthermore, we observed excellent tumor accumulation of the nanoparticles. Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.","[4.0, 4.0, 2.0, 3.0, 5.0]",Medicine,train,3.6,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1038/s41598-017-08692-6,Medicine_530,"Younger children (between 3-5 years old) preferred a more equal distribution of money, and older players, i.e., adolescents and young adults, were more prone to consider the other participants' intentions.",Another important aspect of our approach is the use of meta-analytic decoding.,"Younger children usually prefer egalitarian outcomes, whereas older children and adolescents consider reciprocity and intention. Younger children (between 3-5 years old) preferred a more equal distribution of money, and older players, i.e., adolescents and young adults, were more prone to consider the other participants' intentions. The scientists found that this development of intention-based reciprocity was significantly correlated with the decrease in the cortical thickness of the social brain in late adolescence, specifically the MPFC.","The shift from egalitarianism to intention-based reciprocity was statistically mediated by cortical thinning in the DMPFC and posterior temporal lobe that are known to be involved in processing social information 4, 12, 28-30, 32, 37- 47, 52-56 . Another important aspect of our approach is the use of meta-analytic decoding. We found that the social inference topic was the most spatially consistent with our results among 41 topics that covered a broad range of cognitive processes.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=40322312938&p=1pl&v=1&x=8J0o0AiJ6oUGKUZ8i-_wpQ
10.1038/s41467-018-03725-8,Medicine_531,"With the help of oncology collaborators at the ONJCRI, the researchers demonstrated that the diagnostic approach could be easily translated to the clinic.",In Supplementary Fig.,"""These nanoparticles emit a unique barcoded signal when hit with laser light, and this signal changes ever so slightly if that nanoparticle encounters a CTC and sticks to it, making them easy to detect."" With the help of oncology collaborators at the ONJCRI, the researchers demonstrated that the diagnostic approach could be easily translated to the clinic. The technology successfully tracked in real-time how the diversity of tumour cell populations were changing in response to particular therapies for all of the patients studied, and was highly predictive of treatment effectiveness and patient outcomes.","7 , each antibody-SERS label alone and in combination enable the detection down to 10 cells, demonstrating that our technique is sensitive for cell characterisation. In Supplementary Fig. 8 , Raman intensities showed a positive correlation with increasing cell numbers, and a detection limit of 10 cells was distinguished from the blank PBS signal.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=33835182104&p=1pl&v=1&x=mvlcc2nMKjTf7fD7xDthOQ
10.1016/j.cell.2015.10.069,Medicine_532,"Dr Giulia Rancati, Principal Investigator at IMB and corresponding author of the paper, said, aEURoeWe are thrilled to challenge a longstanding paradigm in genetics, especially one with such clinical implications.","In particular, evolvable genes were enriched for components of subcellular compartments found only in eukaryotes (nucleus, endoplasmic reticulum, Golgi apparatus), but lacked core machineries common to all known cellular systems (mediators of DNA, mRNA and protein synthesis).","With this new paradigm, drug resistance can be predicted at the discovery stage and resources can be optimised to develop more effective drugs that can save lives. Dr Giulia Rancati, Principal Investigator at IMB and corresponding author of the paper, said, aEURoeWe are thrilled to challenge a longstanding paradigm in genetics, especially one with such clinical implications. The next step will be to translate these findings in pathogenic fungi and human cells, and to find non-evolvable essential genes as novel antifungal and chemotherapy targets, respectively.aEUR

Professor Rong Li, Bloomberg Distinguished Professor of Cell Biology and Chemical Biomolecular Engineering at Johns Hopkins University (JHU), and a world renowned expert in cellular asymmetry, division and evolution commented, aEURoeThis is a fantastic study that takes a systematic approach to re-define the essentiality of gene function, taking into account the cellaEUR(tm)s adaptive potential.","Our data also pointed toward specific cellular functions being more evolvable than others. In particular, evolvable genes were enriched for components of subcellular compartments found only in eukaryotes (nucleus, endoplasmic reticulum, Golgi apparatus), but lacked core machineries common to all known cellular systems (mediators of DNA, mRNA and protein synthesis). This finding might imply that while some core functions are so central to cell survival as to prevent major evolutionary changes, it is possible that evolutionarily ''younger'' essential genes might have retained a certain degree of evolvability.","[1.0, 2.0, 1.0, 2.0, 3.0]",Medicine,train,1.8,news,http://healthmedicinet.com/news/scientists-identify-new-paradigm-in-genetics-paving-way-for-development-of-better-drug-targets-to-save-lives/
10.1111/risa.12765,Medicine_533,"It's also relatively cheap compared to space missions, and can help scientists develop new tools for looking into space.",led to an estimated $70 bn cost from lost revenue and satellite replacement for a 1859-calibre superstorm.,"To observe the Sun safely and study the corona during an eclipse, you need the special filters in a spectrometer. Scientists could reconstruct the corona's magnetic field, plasma and other features to finally make sense of this extreme and mysterious environment--and help prepare Earth for its mood swings. It's also relatively cheap compared to space missions, and can help scientists develop new tools for looking into space.","It is likely that many encountered problems remain undisclosed due to commercial and security sensitivities. led to an estimated $70 bn cost from lost revenue and satellite replacement for a 1859-calibre superstorm. The failure of Intelsat's Galaxy-15 spacecraft in April 2010, probably due to space weather, provides a useful case study.","[5.0, 2.0, 1.0, 2.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39594914538&p=1pl&v=1&x=_k2NW0gkLrFN84At_6MBdw
10.1073/pnas.1204651110,Medicine_534,"""In effect, the same climate phenomenon that helped form hurricanes Katrina and Rita along U.S. southern coasts in 2005 also likely caused the severe drought in southwest Amazonia,"" Saatchi said in a statement.",We found no in situ observations over the region affected by the 2005 drought that could be used to directly verify our results.,"The implications of this assessment are important because large-scale droughts can lead to sustained releases of carbon dioxide from decaying wood. ""In effect, the same climate phenomenon that helped form hurricanes Katrina and Rita along U.S. southern coasts in 2005 also likely caused the severe drought in southwest Amazonia,"" Saatchi said in a statement. ""An extreme climate event caused the drought, which subsequently damaged the Amazonian trees.""","The delayed recovery of QSCAT in southwestern Amazonia suggests a decline in more long-lived aspects of canopy structure with recovery timescales greater than 3-4 y, such as loss of leaves or dieback of branches, or potential tree falls creating large gaps. We found no in situ observations over the region affected by the 2005 drought that could be used to directly verify our results. The effects of extreme droughts on the understory light environment of tropical forests may be compared with the effects of tree-fall gaps, although on much larger scales (27) .","[4.0, 4.0, 3.0, 2.0]",Medicine,train,3.25,news,http://www.redorbit.com/news/science/1112766449/climate-change-threat-amazon-rainforest-011813/
10.1016/j.stemcr.2019.01.012,Medicine_535,"This double fail-safe approach, published online ahead of the March 5 issue of Stem Cell Reports, addresses the limitations of PSC-derived beta cells and opens the door to creating safe cell-replacement therapies for people living with T1D.","In contrast, lH1 cells selected with GCV and CB1954 exhibit a stronger (normalized by DNA content) response than the parental line ( Figure 3B, right panel) , in all likelihood reflecting the corresponding enrichment in b cells.","This double fail-safe approach, published online ahead of the March 5 issue of Stem Cell Reports, addresses the limitations of PSC-derived beta cells and opens the door to creating safe cell-replacement therapies for people living with T1D. Looming Clinical Trials Warrant SafeguardsWith clinical trials already initiated using PSC-derived beta cell progenitors and newer approaches with functional beta-like cells on the horizon, the need to ensure patient safety is of paramount importance. Their results demonstrated the removal of all unwanted cells.","Perifused non-treated, differentiated lH1 cells exhibited a glucose-responsive insulin secretion pattern similar to that of differentiated H1 ( Figure 3B , left panel). In contrast, lH1 cells selected with GCV and CB1954 exhibit a stronger (normalized by DNA content) response than the parental line ( Figure 3B, right panel) , in all likelihood reflecting the corresponding enrichment in b cells. The perifusion response of four human islet preparations is shown for comparison in Figure S6 .","[2.0, 1.0, 3.0, 1.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=38582104092&p=1pl&v=1&x=6Ba0bRLrUqzjxGbKPej1Gg
10.1016/j.jrp.2009.03.004,Medicine_536,Employers should be teaching with their employees about the importance of likability and relationship building.,"Similarity of achievement potential (e.g., competitiveness) and intellectual and interest modes (e.g., flexibility and general interests) were less important.","The need to be liked is a fundamentally human one. Employers should be teaching with their employees about the importance of likability and relationship building. Employees should recognize the other person's experience, learn, listen, and validate it.","Similarity of two personality dimensions predicted relationship satisfaction and whether the pair would live together the following year: interpersonal adequacy (e.g., leadership, poise, and general social skills) and, to a lesser extent, character (e.g., maturity, responsibility, and general reliability). Similarity of achievement potential (e.g., competitiveness) and intellectual and interest modes (e.g., flexibility and general interests) were less important. Results suggested that similarity of conscientiousness, but no other big five personality trait, significantly predicted relationship quality after 15 weeks.","[1.0, 3.0, 4.0, 1.0, 3.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=40313783468&p=1pl&v=1&x=SKbYsxu6uxyzE7ymnmeu9Q
10.1016/j.cub.2014.03.011,Medicine_537,"""These species are irreplaceable.","However, with narrow-ranged species concentrating their ED over a small area, parts of the phylogeny are potentially, and precariously, represented only in restricted areas of the world.","By using this as a measure, conservationists can focus their attention on saving species whose loss would serve as the greatest blow to species diversity and the history of evolution. ""These species are irreplaceable. If they are driven to extinction, millions of years or evolutionary history goes with them.""","We noted above that in birds, high-ED species per se are not geographically more restricted than lower-ED species, which means that they are unlikely to be threatened by shrinking or shifting habitats alone. However, with narrow-ranged species concentrating their ED over a small area, parts of the phylogeny are potentially, and precariously, represented only in restricted areas of the world. Indeed, global change is expected to induce both rapid range extensions and range losses in species, often quite independent of current formal threat categorizations , with direct consequences for the spatial concentration and thus potential for global loss of evolutionary information.","[4.0, 3.0, 1.0, 4.0, 5.0]",Medicine,train,4.0,news,http://www.natureworldnews.com/articles/6595/20140411/words-top-100-most-unique-and-endangered-birds-defined-in-new-study.htm
10.1126/sciadv.aau2477,Medicine_538,"Almost 26 cubic kilometers of floodwater was temporarily stored on land, evaporating (or transpiring through plant leaves) much more slowly at about one cubic kilometer per day.","Inversion of these data shows that a third of Harvey's total stormwater was captured on land (25.7 ± .0 km ), indicating that the rest drained rapidly into the ocean at a rate of 8.2 km","That's far more water than was captured by stations measuring river flow, showing that much of the water either did not drain through major channels or entered those channels downstream of the last measuring station. Almost 26 cubic kilometers of floodwater was temporarily stored on land, evaporating (or transpiring through plant leaves) much more slowly at about one cubic kilometer per day. It took five weeks for the GPS measurements to return to their pre-Harvey state, bouncing back as the land was relieved of the excess water's weight.","Water left in Harvey's wake should cause elastic loading and subsidence of Earth's crust, and uplift as it drains into the ocean and evaporates. Inversion of these data shows that a third of Harvey's total stormwater was captured on land (25.7 ± .0 km ), indicating that the rest drained rapidly into the ocean at a rate of 8.2 km Over a period of 7 days, Harvey produced record-breaking rainfall, with 1.54 m of precipitation measured southeast of Houston, causing extensive flooding and $125 billion in damage, an amount second only to Hurricane Katrina .","[4.0, 4.0, 2.0, 4.0]",Medicine,train,3.5,news,http://ct.moreover.com/?a=37162222017&p=1pl&v=1&x=z5_0Kp-tV0-CvrEXDLiG_A
10.1093/geronb/gbv101,Medicine_539,All of the people in the study reported that they thought they looked around 10 years younger than they actually were.,"Taken together, we predict that when a significant relationship exists between daily stressors and subjective age, it will be mediated by positive affect, personal control, and negative affect.","""We found they seemed to be less perturbed by everyday stress,"" says Bellingtier. All of the people in the study reported that they thought they looked around 10 years younger than they actually were. But on stressful days, those who had undergone major stress in the past thought they looked 20 years younger while people who hadn't experienced a major change were more likely to say they looked their actual age.","We further suspect that on a daily level, individuals' subjective age may be influenced by negative affect. Taken together, we predict that when a significant relationship exists between daily stressors and subjective age, it will be mediated by positive affect, personal control, and negative affect. Nearly all participants reported their employment status as retired (n = 41).","[3.0, 3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://time.com/4117072/major-stress-helps-you-weather-smaller-stress/
10.1007/s00125-014-3400-z,Medicine_54,"They conclude: ""This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection.",The findings suggest that a vaccination strategy against EV infection might slow the rising incidence of type 1 diabetes.,"They add: ""Taiwan has relatively low type 1 diabetes incidence; we believe that the marked escalation of the said incidence in recent decades can be largely attributed to the highly endemic spread of enterovirus infection in Taiwanese children, given that there has been little gene flow and genetic drift in such a short period."" They conclude: ""This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection. Our results suggest that preventive strategies, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.""","Whilst the evidence of an association between EV infection and pathogenesis is observational, the conclusions are solid enough to guide further research on this association. The findings suggest that a vaccination strategy against EV infection might slow the rising incidence of type 1 diabetes. Duality of interest The authors declare that there is no duality of interest associated with this manuscript.","[2.0, 3.0, 3.0, 2.0]",Medicine,train,2.5,news,http://www.sciencedaily.com/releases/2014/10/141017183715.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1080/15560350802081314,Medicine_540,"Alyssa relapsed, and overdosed on pills.","While an outcome study is needed, it was determined that a rigorous experimental or quasi-experimental trial would be premature before (a) understanding the nature of programs in operation and (b) assessing the feasibility of an outcome study.","But when she came back to Ohio and started school, peer pressure made it hard to remember what she learned. Alyssa relapsed, and overdosed on pills. Alyssa's experience is a common one.","By providing a frame which was deliberatively conceived by professionals and recovering students, however, the ARS membership criteria did serve as a guide for defining schools which were invited to participate. While an outcome study is needed, it was determined that a rigorous experimental or quasi-experimental trial would be premature before (a) understanding the nature of programs in operation and (b) assessing the feasibility of an outcome study. The prior projects described above and the ARS guidelines for membership set the stage for the project.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39825977404&p=1pl&v=1&x=wzJX19N-iCvOfpLz256iDQ
10.1111/j.1360-0443.2010.02899.x,Medicine_541,"Logging only fat would yield 10.5gram; and a combo of each would yield 11.9gram of carbs and 5.25gram of fat.Sugar alcohols can raise an individual's blood sugar, albeit much lower than actual sugar, so they still need to be counted as carbs (~2kCal/gram), if tracking.",The variation in the effect of alcohol consumption on different types of stroke may be ascribed to the difference in the causes of haemorrhagic and ischaemic stroke.,"(Side note: there's a trace amount of protein to completely count everything. Logging only fat would yield 10.5gram; and a combo of each would yield 11.9gram of carbs and 5.25gram of fat.Sugar alcohols can raise an individual's blood sugar, albeit much lower than actual sugar, so they still need to be counted as carbs (~2kCal/gram), if tracking. Just because something doesn't exert an insulin response does not mean it is free of calories.","According to these meta-analyses, low to moderate alcohol consumption (one to two drinks per day) seemed to have a protective effect on ischaemic stroke, and then the risk curve turned upwards. The variation in the effect of alcohol consumption on different types of stroke may be ascribed to the difference in the causes of haemorrhagic and ischaemic stroke. Consequently, a pattern of irregular heavy drinking occasions should also have the same detrimental effects as for IHD.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://ct.moreover.com/?a=33869739377&p=1pl&v=1&x=2-Vfb5SGnEgGbA_1Dt6Pqw
10.1073/pnas.1403382111,Medicine_542,"It identifies an important component in regulation and this 'stop mechanism' may prevent complications from excessive water intake,"" he said.","Additionally, a distributed network of regions, including the insula, MCC, amygdala, midbrain, cerebellum, and PAG showed drinking-related activation related to the experience of unpleasantness that accompanies drinking water when already fully satiated.","""Different areas of the brain involved in emotional decision-making were activated when people drank water after becoming thirsty and when study participants followed instructions to keep drinking when no longer thirsty. It identifies an important component in regulation and this 'stop mechanism' may prevent complications from excessive water intake,"" he said. Denton believes the findings could be applied to other aspects of human gratification.","We propose that this cause is an inhibitory mechanism that prevents overdrinking from taking place postsatiation. Additionally, a distributed network of regions, including the insula, MCC, amygdala, midbrain, cerebellum, and PAG showed drinking-related activation related to the experience of unpleasantness that accompanies drinking water when already fully satiated. During the thirst condition, participants with the highest pleasantness ratings showed the greatest activation in the OFC and pACC.","[3.0, 2.0, 3.0, 4.0]",Medicine,train,3.0,news,http://www.theepochtimes.com/n3/593542-your-brain-knows-when-your-thirst-is-quenched/
10.2460/javma.242.11.1549,Medicine_543,"Ten were found more frequently among purebred dogs, and one such disorder was more common in mixed-breeds.","Additionally, clients are willing to pursue more extensive treatment at a referral hospital.","The researchers found that the prevalence of 13 of the 24 genetic disorders was approximately the same in purebred dogs as in their mixed-breed counterparts. Ten were found more frequently among purebred dogs, and one such disorder was more common in mixed-breeds. The data also indicated that the more recently derived breeds or those breeds that shared a similar lineage were more susceptible to certain inherited disorders.","This would cause an overrepresentation of some disorders in purebred dogs. Additionally, clients are willing to pursue more extensive treatment at a referral hospital. Owners of purebred dogs are more likely to spend more on their dogs than are owners of mixed-breed dogs, which would result in a greater proportion of purebred dogs, as seen in the present study.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.healthcanal.com/genetics-birth-defects/39146-purebred-dogs-not-always-at-higher-risk-for-genetic-disorders-study-finds.html
10.1093/aje/kwm375,Medicine_545,"(c) Aangeboden door Business Insider Inc Shutterstock

Als de griep neerdaalt in je huishouden, stellen we ons er al snel op in dat we zelf ook ziek zullen worden binnen niet al te lange tijd.",A total of 827 papers were selected (figure 1).,"(c) Aangeboden door Business Insider Inc Shutterstock

Als de griep neerdaalt in je huishouden, stellen we ons er al snel op in dat we zelf ook ziek zullen worden binnen niet al te lange tijd. Ook als je zorgt voor een zieke partner of een grieperig kind. (c) Aangeboden door Business Insider Inc

Foto: Shutterstock

De kans dat je griep oploopt via een andere persoon, is relatief groot.","However, these percentages come from pre-and postinfluenza-season serologic studies, and they may therefore be subject to recall bias when individuals were asked whether they had had influenza-like illness during winter or to classification bias due to lack of sensitivity of laboratory tests . A total of 827 papers were selected (figure 1). Differences were resolved by discussion and consensus.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=37360360866&p=1pl&v=1&x=ovfeGx1RmpUVOmDW-nAgvA
10.1098/rspb.2013.1698,Medicine_546,"After multiple exposures to a striking visual pattern, neurons in the retina and visual cortex of the brain fire less frequently the next time you see the pattern.","The average time spent in REM was negatively correlated with SWS duration, which, in turn, can explain the negative correlation that was found for SWS duration and adaptation and for low-frequency power in the delta and theta range and adaptation.","After multiple exposures to a striking visual pattern, neurons in the retina and visual cortex of the brain fire less frequently the next time you see the pattern. By devoting less energy to familiar sights, the brain is free to concentrate on the next new thing that comes along; the original image becomes a routine perception. These nappers perceived the original faces to be compressed, whereas a group who simply wore a blindfold for 90 minutes didn't show this adaptation.","Participants who exhibited high amounts of REM sleep also showed greater adaptation. The average time spent in REM was negatively correlated with SWS duration, which, in turn, can explain the negative correlation that was found for SWS duration and adaptation and for low-frequency power in the delta and theta range and adaptation. Adaptation was further predicted by spindle density of both slow and fast spindles, however in opposite ways.","[2.0, 1.0, 2.0, 1.0, 1.0]",Medicine,train,1.4,news,http://news.sciencemag.org/brain-behavior/2013/08/i%E2%80%99ve-grown-accustomed-face
10.1016/j.biopsych.2015.04.026,Medicine_547,"This may seem counterintuitive, but Moghaddam says it makes perfect sense.","Thus, during extinction, adolescent VTA neurons maintained a strong phasic response to a cue previously predictive of reward availability.","Anticipation isn't enough

The new findings, published in the journal Biological Psychiatry, show that when adolescents are faced with the prospect of a reward, their dopamine neurons are actually activated less than in adults. This may seem counterintuitive, but Moghaddam says it makes perfect sense. Adult rats get a small dopamine rush from simply anticipating a reward, while adolescent rats don't get the same level of dopamine-based satisfaction.","In session 8, which was an entirely extinction session, adolescent cue responses were significantly greater than adults (F 1,127 5 6.430, p 5 .012; Figure 2B ). Thus, during extinction, adolescent VTA neurons maintained a strong phasic response to a cue previously predictive of reward availability. There were no age-related differences in action-or reward-evoked activity during extinction (action: F 1,127 5 2.121, p 5 .121; reward: F 1,127 5 .317, p 5 .574), indicating that other task-related events are processed similarly by both age groups during extinction.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.futurity.org/teenagerss-risk-reward-dopamine-951052/
10.1038/s41467-018-05526-5,Medicine_548,"After a few weeks, roles had redistributed in both groups!","The incomer mouse #5 switched less, whereas the resident mouse #6 switched more in step 2 compared to step 1. d Switch variation between step 1 and 2 (ΔSW) for incomers and residents (two-sample t-test, t(27) = 2.9401).","Therefore, one can say that mice have biologically inscribed individuality. After a few weeks, roles had redistributed in both groups! Some mice who had rarely varied their choice had become the more adventurous ones in their new group, and vice versa.","b Cumulative distribution of SW for steps 1 (purple) and 2 (green) (D = 0.2069, p = 0.57). The incomer mouse #5 switched less, whereas the resident mouse #6 switched more in step 2 compared to step 1. d Switch variation between step 1 and 2 (ΔSW) for incomers and residents (two-sample t-test, t(27) = 2.9401). (Right) SW is different for the same two groups after step 2 (Two-sample t-test (t = 3.5914, **p < 0.01)).","[1.0, 1.0, 3.0, 1.0, 4.0]",Medicine,train,1.0,news,https://www.sciencedaily.com/releases/2018/08/180806073138.htm
10.1126/science.aao0432,Medicine_549,"So, it remains to be seen if, or how, the 34-page framework will translate into actual policy changes, like more humanitarian visas for those displaced by drought or rising seas.","We show a quadratic response function (dashed brown line), as well as flexible restricted cubic splines (solid brown line).","Several EU countries joined the US and Australia in opting not to adopt the document. So, it remains to be seen if, or how, the 34-page framework will translate into actual policy changes, like more humanitarian visas for those displaced by drought or rising seas. ""It is difficult to say,"" Gemenne said.","The coefficients on temperature are displayed in Fig. We show a quadratic response function (dashed brown line), as well as flexible restricted cubic splines (solid brown line). These models correspond to columns (1a) and (3a) of table S1, respectively.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://ct.moreover.com/?a=37956093465&p=1pl&v=1&x=jt9X3KNlGqIE0laIMZIedg
10.1007/s13524-014-0321-x,Medicine_55,"Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","The OLS specification suggests that happiness increases significantly one year before the birth, stays at an elevated level in the year of birth, and then quickly returns to pre-birth levels.","Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Modeling these as time-varying would not change the results. The OLS specification suggests that happiness increases significantly one year before the birth, stays at an elevated level in the year of birth, and then quickly returns to pre-birth levels. Happiness stays at this level from when the first child is young through when the child reaches adult ages.","[2.0, 5.0, 4.0, 3.0, 3.0]",Medicine,train,3.4,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1417259112,Medicine_551,"Picking a needle out of a haystack might seem like the stuff of fairytales, but our brains can be electrically ""tuned"" to enable us to do a much better job of finding what we're looking for, even in a crowded and distracting scene, new research indicates.","Additionally, by fitting these behavioral RT data with a logarithmic function to model the rate of improvement (9), we found that anodal tDCS significantly increased the rate parameters of RT speeding (F 1,17 = 5.097, P = 0.037).","Picking a needle out of a haystack might seem like the stuff of fairytales, but our brains can be electrically ""tuned"" to enable us to do a much better job of finding what we're looking for, even in a crowded and distracting scene, new research indicates. The new findings, published Dec. 1, 2014, in the Proceedings of the National Academy of Science, challenge our current understanding of how visual attention is focused and the roles of short and long-term memory. ""These new findings provide evidence that long-term memory representations can also underlie our ability to rapidly configure attention to focus on certain objects, and that long-term memory performance can be sharply accelerated using electrical stimulation.""","This striking causal aftereffect of anodal tDCS was evidenced by a stimulation condition × target repetition interaction on RTs (F 2,34 = 3.735, P = 0.042), with this RT effect being significant between the first two trials of search for a particular Landolt C (F 1,17 = 6.204, P = 0.023) but with no significant change thereafter (P > 0.310). Additionally, by fitting these behavioral RT data with a logarithmic function to model the rate of improvement (9), we found that anodal tDCS significantly increased the rate parameters of RT speeding (F 1,17 = 5.097, P = 0.037). Consistent with the interpretation that tDCS changed how attention selected the targets in the search arrays, we found that the N2-posterior-contralateral (N2pc) component, an index of the deployment of covert attention to the possible target in a search array (26), showed a pattern that mirrored the single-trial RT effects (F 1,17 = 4.792, P = 0.043) ( Fig.","[3.0, 3.0, 2.0, 1.0, 2.0]",Medicine,train,2.2,news,http://www.sciencedaily.com/releases/2015/01/150114090817.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1073/pnas.1306983110,Medicine_552,"The virtual effort is similar to performance capture filming of actors for later computer-animated visual effects for such films as ""The Lord of the Rings.""","We show that jellyfish exhibit a unique mechanism of passive energy recapture, which is exploited to allow them to travel 30% further each swimming cycle, thereby reducing metabolic energy demand by swimming muscles.","The computer modeled jellyfish - unlike the real gelatinous zooplankton filmed in lab settings -- allows researchers to control movements of the creature however fast they wish, and in any desired direction. The virtual effort is similar to performance capture filming of actors for later computer-animated visual effects for such films as ""The Lord of the Rings."" Stewart said it was ""remarkably difficult"" to capture the flexibility and soft edges of the jellyfish into a full, controllable computational framework versus a more rigid body such as a shark or a human swimmer whose movements can more easily be modeled because of their joints.","Results from this study also have implications for bioinspired design, where low-energy propulsion is required. We show that jellyfish exhibit a unique mechanism of passive energy recapture, which is exploited to allow them to travel 30% further each swimming cycle, thereby reducing metabolic energy demand by swimming muscles. By accounting for large interspecific differences in net metabolic rates, we demonstrate, contrary to prevailing views, that the jellyfish (Aurelia aurita) is one of the most energetically efficient propulsors on the planet, exhibiting a cost of transport (joules per kilogram per meter) lower than other metazoans.","[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.sciencedaily.com/releases/2013/10/131017173356.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1111/desc.12068,Medicine_553,"The Quest to Learn public school in New York City offers a glimpse of how gaming is already transforming not just how students learn, but also what they learn.","There were few significant differences between the two control groups, suggesting that the gains associated with adaptive training are unlikely to be due to expectancy effects.","Gamestars

Testing fatigue, combined with more pervasive computer use in and out of the classroom and continued experimentation with games as learning tools, suggests that such video games will play a significant role in the future of education. The Quest to Learn public school in New York City offers a glimpse of how gaming is already transforming not just how students learn, but also what they learn. ""Games are also uniquely suited to fostering the skills necessary for navigating a complex, interconnected, rapidly changing 21st century,"" he adds.","Children who completed adaptive training made significantly greater improvements in tests of visuo-spatial STM and verbal and visuo-spatial WM than either children who completed a non-adaptive version of training or those who received no intervention. There were few significant differences between the two control groups, suggesting that the gains associated with adaptive training are unlikely to be due to expectancy effects. This is the first double-blinded RCT study on this key group of poor learners that meets stringent criteria for intervention research (e.g.","[1.0, 1.0, 2.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.scientificamerican.com/article/fact-or-fiction-video-games-are-the-future-of-education/
10.1126/sciadv.1500045,Medicine_554,"""With X-ray crystallography, we were able to see very beautiful patterns, which was a very exciting discovery.","5B) , including a net bleach near 500 nm and two net positive features of excited-state absorption at~580 and 640 nm (Fig.","The crystal structure of the Au133 nanoparticle divulged many secrets. ""With X-ray crystallography, we were able to see very beautiful patterns, which was a very exciting discovery. These patterns only show up when the nanoparticle size becomes big enough,"" Jin said.","Upon photoexcitation above the optical gap, we observe three primary transient optical features (Fig. 5B) , including a net bleach near 500 nm and two net positive features of excited-state absorption at~580 and 640 nm (Fig. The bleach at 500 nm correlates to the ground-state transition at 503 nm observed in Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143139.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2010.0157,Medicine_555,Behavior can be classified as cooperative if it provides a benefit to another individual (recipient) or is beneficial to both the individual and the recipient.,"At the same time, these enforcement mechanisms are key in maintaining mutual cooperation in large groups and solving CAPs.","Behavior can be classified as cooperative if it provides a benefit to another individual (recipient) or is beneficial to both the individual and the recipient. The main message of their report is that in comparison with other animals have a larger toolbox of instruments used to sustain cooperation. Helping behavior builds up a reputation and individuals, who have a good name, have more chances to get support from the others in the future.","This allows humans to engage in direct and indirect reciprocity and maintain cooperative interactions at a dyadic level between unrelated individuals. At the same time, these enforcement mechanisms are key in maintaining mutual cooperation in large groups and solving CAPs. The possibility of using language to exchange social information is probably the most important difference.","[1.0, 2.0, 3.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.technology.org/2014/04/17/specific-human-cooperation/
10.1073/pnas.1703958114,Medicine_556,What they discovered clarifies animals' feeding behavior and the science of decision-making.,"It should be noted that in our model at any given time a worm may be sampling, committed to pumping, or pausing.","What they discovered clarifies animals' feeding behavior and the science of decision-making. ""It's an interesting model for understanding the processes that underlie how animals decide where and when to eat,"" says lead author Monika Scholz, an international student research fellow with the University of Chicago's biophysical sciences program who is now at Princeton University. ""For these worms, it's all about the balance between speed and accuracy.""","All information gathered from previous samples is thus erased and our model does not include long-term memory or learning (see Discussion). It should be noted that in our model at any given time a worm may be sampling, committed to pumping, or pausing. However, when observing the time trace of pumping one can only discern pumping from pausing.","[2.0, 1.0, 1.0, 2.0, 1.0]",Medicine,train,1.4,news,http://www.futurity.org/roundworms-c-elegans-decisions-food-1518062/
10.1016/j.celrep.2013.07.022,Medicine_558,The lab's results are described in the August 29 issue of Cell Reports.,"Almost all planarian muscle cells express PCGs, suggesting a dual function: contraction and control of patterning.","When part of a planarian was cut off, the muscle cells in the body wall altered which PCGs they expressed in response to the wounding. The lab's results are described in the August 29 issue of Cell Reports. Yet, these functions may also explain why muscle cells are so well suited to secrete the proteins coded for by the PCGs.","Almost all planarian muscle cells express PCGs, suggesting a dual function: contraction and control of patterning. PCG expression is dynamic in muscle cells after injury, even in the absence of neoblasts, suggesting that muscle is instructive for regeneration. We conclude that planarian regeneration involves two highly flexible systems: pluripotent neoblasts that can generate any new cell type and muscle cells that provide positional instructions for the regeneration of any body region.","[2.0, 1.0, 1.0, 2.0]",Medicine,train,1.5,news,http://www.sciencedaily.com/releases/2013/08/130815133105.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/nature24303,Medicine_559,The almost simultaneous detections of both gravitational waves and gamma rays from GW170817 raised hopes that this object was indeed a long-sought kilonova and observations with ESO facilities have revealed properties remarkably close to theoretical predictions.,In Fig.,"This makes the source both the closest gravitational wave event detected so far and also one of the closest gamma-ray burst sources ever seen. The almost simultaneous detections of both gravitational waves and gamma rays from GW170817 raised hopes that this object was indeed a long-sought kilonova and observations with ESO facilities have revealed properties remarkably close to theoretical predictions. Following the merger of the two neutron stars, a burst of rapidly expanding radioactive heavy chemical elements left the kilonova, moving as fast as one-fifth of the speed of light.",opacities of around κ = 10 cm 2 g −1 would be likely . In Fig. 3 we show the best fits forcing κ = 10 cm 2 g −1,"[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/DjjnRDYz368/
10.1001/jama.2014.15690,Medicine_56,"At 5 years after randomization, the cumulative primary event rate was similar in participants in the aspirin group (2.77 percent) and those in the no aspirin group (2.96 percent).","The 5-year cumulative primary outcome event rate was not significantly different between the groups (2.77% [95% CI, 2.40%-3.20%] for aspirin vs 2.96% [95% CI, 2.58%-3.40%] for no aspirin; hazard ratio [HR], 0.94 [95% CI, 0.77-1.15]; P = .54).","The researchers found that there was no statistically significant difference between the two groups in time to the primary end point (a composite of death from cardiovascular causes, nonfatal stroke, and nonfatal heart attack). At 5 years after randomization, the cumulative primary event rate was similar in participants in the aspirin group (2.77 percent) and those in the no aspirin group (2.96 percent). Aspirin significantly reduced incidence of nonfatal heart attack and transient ischemic attack, and significantly increased the risk of extracranial hemorrhage requiring transfusion or hospitalization.","Patients with an occurrence of nonfatal stroke totaled 114 in the aspirin group and 108 in the no aspirin group; of nonfatal myocardial infarction, 20 in the aspirin group and 38 in the no aspirin group; of undefined cerebrovascular events, 3 in the aspirin group and 5 in the no aspirin group. The 5-year cumulative primary outcome event rate was not significantly different between the groups (2.77% [95% CI, 2.40%-3.20%] for aspirin vs 2.96% [95% CI, 2.58%-3.40%] for no aspirin; hazard ratio [HR], 0.94 [95% CI, 0.77-1.15]; P = .54). Aspirin significantly reduced incidence of nonfatal myocardial infarction (0.30 [95% CI, 0.19-0.47] for aspirin vs 0.58 [95% CI, 0.42-0.81] for no aspirin; HR, 0.53 [95% CI, 0.31-0.91]; P = .02) and transient ischemic attack (0.26 [95% CI, 0.16-0.42] for aspirin vs 0.49 [95% CI, 0.35-0.69] for no aspirin; HR, 0.57 [95% CI, 0.32-0.99]; P = .04), and significantly increased the risk of extracranial hemorrhage requiring transfusion or hospitalization (0.86 [95% CI, 0.67-1.11] for aspirin vs 0.51 [95% CI, 0.37-0.72] for no aspirin; HR, 1.85 [95% CI, 1.22-2.81]; P = .004).","[5.0, 5.0, 4.0, 5.0]",Medicine,train,4.75,news,http://www.newswise.com/articles/effect-of-once-daily-low-dose-aspirin-on-cv-death-and-other-outcomes
10.1038/s41746-018-0033-5,Medicine_560,Schatz envisions everyone over 60 having a phone app that constantly records their motion.,This finding suggests use of accelerometer to assess characteristics of movement beyond only gait characteristics may improve predictive ability.,"Data extracted automatically from the devices predicted falls with an average of 73.7 percent accuracy and 81.1 percent for precision, the researchers report, noting that accelerometer-based measures of gait are potentially useful in screening older women for fall risk. Schatz envisions everyone over 60 having a phone app that constantly records their motion. ""I work a lot with primary care physicians, and they love this [idea], because they only see people after they start falling,"" Schatz said.","[] [] Greater accuracy, sensitivity, and specificity can be achieved with multiple sensors on body parts other than the waist. This finding suggests use of accelerometer to assess characteristics of movement beyond only gait characteristics may improve predictive ability. Of course, this pilot study has several limitations.","[1.0, 3.0, 5.0, 3.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34528601138&p=1pl&v=1&x=69-rKRDpo5a6UlO1u9oP6w
10.1098/rsbl.2014.0255,Medicine_561,"""So whatever is happening in terms of evolution of the bird population and the parasite population is most likely in the earliest stages of that process.""","Similarly, D. regalis showed an extraordinarily high degree of population genetic structure among geographical islands.","""Our study empirically demonstrates an important evolutionary process in which the hawks separate into different populations, and the lice living on them do the same."" ""So whatever is happening in terms of evolution of the bird population and the parasite population is most likely in the earliest stages of that process."" A better understanding of how parasites and their hosts coevolve has implications for biomedical sciences, according to Whiteman.","Further analysis of the genetic clusters revealed a clear correspondence with the geographical islands on which populations were sampled. Similarly, D. regalis showed an extraordinarily high degree of population genetic structure among geographical islands. AMOVA and pairwise permutation tests showed that populations of lice on each island were highly differentiated (overall F ST ¼ 0.429, p , 0.0001).","[3.0, 2.0, 1.0, 1.0]",Medicine,train,1.75,news,http://www.sciencedaily.com/releases/2014/08/140806173840.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1086/672271,Medicine_562,SHEA upholds the value and critical contributions of healthcare epidemiology to improving patient care and healthcare worker safety in all healthcare settings.,"58 To completely eliminate any risk of HIV transmission to her infant, the provider may want to consider stopping breast-feeding.","Many of the revised recommendations are intended to make the PEP regimen better tolerated, increasing the possibility that HCP complete the full regimen. As such, the updated guidelines should be distributed and made readily available to emergency physicians and other providers as needed. SHEA upholds the value and critical contributions of healthcare epidemiology to improving patient care and healthcare worker safety in all healthcare settings.","46 The lactating healthcare provider should be counseled regarding the high risk of HIV transmission through breast milk should acute HIV infection occur (in a study in Zimbabwe, the risk of breast milk HIV transmission during the 3 months after seroconversion was 77.6 infections per 100 child-years). 58 To completely eliminate any risk of HIV transmission to her infant, the provider may want to consider stopping breast-feeding. Ultimately, lactating women with occupational exposures to HIV who will take antiretroviral medications as PEP must be counseled to weigh the risks and benefits of continued breast-feeding both while taking PEP and while being monitored for HIV seroconversion.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.healthcanal.com/infections/hiv-and-aids/41583-new-federal-guidelines-for-managing-occupational-exposures-to-hiv.html
10.1126/science.1237973,Medicine_564,"""LncRNAs, unlike proteins, really can use their genomic information -- their context, their location -- to act, to bring together targets,"" he says.",We found that the localization of A Xist over the whole X-chromosome looked broadly comparable to that of wild-type Xist (Fig.,"He adds that the work provides one of the first direct pieces of evidence to explain what makes lncRNAs special. ""LncRNAs, unlike proteins, really can use their genomic information -- their context, their location -- to act, to bring together targets,"" he says. ""That makes them quite unique.""","Together, these results suggest that the initial localization of Xist is hindered by some feature of actively transcribed genes but that Xist can eventually overcome this barrier to spread across these regions. We found that the localization of A Xist over the whole X-chromosome looked broadly comparable to that of wild-type Xist (Fig. 5C, Fig.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.sciencedaily.com/releases/2013/07/130705212230.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.15252/embj.201488795,Medicine_566,"That, in turn, causes more of the Alzheimer's-related protein to be produced, Golde says.","Distribution of flotillin-1, a marker for lipid rafts, was not affected (Fig 3E) .","The experiments reveal more about the mechanics of a likely relationship between stress and Alzheimer's disease. That, in turn, causes more of the Alzheimer's-related protein to be produced, Golde says. One possible solution--blocking the CRF receptor that initiates the stress-induced process that generates Alzheimer's-related proteins--didn't work.","CRF treatment altered the distribution of PS1 in cells expressing wild-type CRFR1, but in cells expressing the CRFR1 D386/IC3 mutant, the distribution of PS1 was unchanged. Distribution of flotillin-1, a marker for lipid rafts, was not affected (Fig 3E) . In multiple clonal lines, stable overexpression of wild-type CRFR1 also resulted in an increase in the PS1 in the raft fractions ( Supplementary Fig S3C and D) .","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.futurity.org/stress-alzheimers-disease-1007782/
10.1016/j.jpeds.2016.10.002,Medicine_567,"A multidisciplinary approach, Sharp adds, also provides important safeguards when introducing food to children with little or no experience consuming food.","-, All 11 studies presented data reflecting changes in oral consumption.","This study is the first meta-analysis of all published, peer-reviewed research focusing on children receiving intensive multidisciplinary intervention at day hospital and inpatient treatment programs. A multidisciplinary approach, Sharp adds, also provides important safeguards when introducing food to children with little or no experience consuming food. In addition to providing support for multidisciplinary intervention, recommendations from the study include: 1) active participation of caregivers in the treatment process - ideally with structured training procedures to support generalization into the home; 2) a formal discharge plan that involves regular outpatient follow-up to support families in maintaining and expanding upon treatment gains; and 3) use of a behavioral approach to structure meals and address mealtime difficulties (e.g., tantrums; food refusal) that prohibit consumption.","Across studies, the number and definition of outcome measures varied (Table V; available at www.jpeds.com). -, All 11 studies presented data reflecting changes in oral consumption. Of these, 8 reported the percentage of patients weaned from enteral feeds, 6 reported the percentage of calories received by oral vs enteral feeds, and 4 reported on the volume of food consumed (eg, grams, kcal).","[1.0, 2.0, 2.0, 1.0, 2.0]",Medicine,train,1.6,news,http://healthmedicinet.com/news/intensive-multidisciplinary-intervention-holds-benefit-for-children-with-pediatric-feeding-disorders/
10.1038/nm.4296,Medicine_568,"""This discovery is the perfect example of how we take basic science discoveries and translate them to cure diseases at Northwestern Medicine.""",1d and Supplementary Fig.,"The collaborative environment at Northwestern made the discovery possible, Shilatifard said. ""This work could not have been done anywhere in the world except Northwestern Medicine, because of all the scientists and physicians who have been recruited here during the past five years and how they work together to link basic scientific research to the clinic,"" Shilatifard said. ""This discovery is the perfect example of how we take basic science discoveries and translate them to cure diseases at Northwestern Medicine.""","Interestingly, upon loss of H3K27me3, these nucleosomes acquire H3K27ac, which results in the formation of H3K27M-K27ac heterotypic nucleosomes 4 ( Fig. 1d and Supplementary Fig. These observations support the increased association of acetyl-binding bromodomain proteins to H3K27M-containing nucleosomes , and they prompted us to investigate the role of these proteins in DIPG cells.","[1.0, 3.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/nkWRzOXqal0/
10.1016/j.physbeh.2009.12.026,Medicine_569,"Hey, it beats giving into impulses every time they come up!",This agrees with work in both animal models and humans ] that show about 70-75% of drinking occurs peri-prandially.,"After all, you don't have to eat healthy 100 percent of the time. Hey, it beats giving into impulses every time they come up! It's as simple as that.","Otherwise, the peaks are highly synchronous. This agrees with work in both animal models and humans ] that show about 70-75% of drinking occurs peri-prandially. The weekday versus weekend differences in ingestive episodes highlight the importance of lifestyle and social custom on this activity .","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.theepochtimes.com/n3/1380572-8-ways-to-combat-food-cravings/
10.1007/s00213-019-05253-9,Medicine_570,They also found that when cells were pre-treated with the lipid they were more resistant to inflammation when stimulated.,The top 20 differentially expressed genes are reported in Fig.,"""This new paper helps clarify that."" They also found that when cells were pre-treated with the lipid they were more resistant to inflammation when stimulated. ""It seems that these bacteria we co-evolved with have a trick up their sleeve,"" said Lowry.","Of the 203 differentially expressed genes, 109 were downregulated in the 10(Z)-hexadecenoic acid condition, and 20% of those genes were associated with proinflammatory processes (Table S4 ). The top 20 differentially expressed genes are reported in Fig. Consistent with the ex vivo macrophage experiments measuring IL-6 protein with ELISA, the second most significantly differentially expressed transcript was IL-6 (Table S3) .","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39822828994&p=1pl&v=1&x=E6y_2l3_5RNxQtw1lkssQQ
10.1001/jamapsychiatry.2016.2600,Medicine_571,"The findings also could help scientists who study the genetics of autism understand how mutations in a single gene can contribute to symptoms of autism, such as problems with social and language skills and repetitive behaviors.","Of 207 patients with available ADHD data (eFigure 1 in the Supplement), 94 (45.4%; 95% CI, 38.8%-52.4%) exhibited abovethreshold ADHD scores, and, in categorical evaluation of severe ADHD symptoms (AI T score ≥65), the male to female ratio was 1:1.","""In the past, we didn't really understand the association between NF1 and autism, but now we have new insights into the problem, which will allow us to design better treatments for children with NF1 and autism."" The findings also could help scientists who study the genetics of autism understand how mutations in a single gene can contribute to symptoms of autism, such as problems with social and language skills and repetitive behaviors. It is equally common in both sexes and in all ethnic groups.","However, despite this correlation, quantitative ASD and ADHD trait scores generated highly contrasting distributions ( Figure 1C ). Of 207 patients with available ADHD data (eFigure 1 in the Supplement), 94 (45.4%; 95% CI, 38.8%-52.4%) exhibited abovethreshold ADHD scores, and, in categorical evaluation of severe ADHD symptoms (AI T score ≥65), the male to female ratio was 1:1. As expected, individuals with above-threshold ADHD scores demonstrated statistically significantly higher QAT scores (mean difference, 13.70; 95% CI, 10.34-17.06) compared with those with lower ADHD trait scores; however, more than half of the patients with available ADHD data (111 [53.6%]) exhibited a QAT burden in the normal range (T score <60).","[2.0, 1.0, 1.0, 1.0]",Medicine,train,1.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/SumzKyaN7os/
10.1001/jamapsychiatry.2017.4516,Medicine_573,"The researchers found that compared with converted adolescent females, those in the resilient group had greater connectivity between the amygdala and orbitofrontal cortex and between the dorsolateral prefrontal cortex and frontotemporal regions.",All of the participants were post-menarche at the time of scanning (age of menarche 12.331.32 years; 6.802.52 years before the MRI scan).,"Twenty were at high risk and did not develop depression (resilient), 20 were at high risk and did develop depression (converted), and 25 were at low risk with no history of psychopathology (control). The researchers found that compared with converted adolescent females, those in the resilient group had greater connectivity between the amygdala and orbitofrontal cortex and between the dorsolateral prefrontal cortex and frontotemporal regions. In the resilient group only, there was a correlation for strength of amygdala-orbitofrontal cortex connectivity with positive life events.","By shifting the focus of future research to a resiliencebased model of mental health, and by investigating characteristics of high-risk individuals who remain resilient, we may increase our understanding of how to optimize resilience to psychopathology. All of the participants were post-menarche at the time of scanning (age of menarche 12.331.32 years; 6.802.52 years before the MRI scan). Parenthetically, Tanner staging ranged from 1 to 4.5 (3.201.10; average of breast and hair rating) at study entry, an average of six years before the neuroimaging scans.","[2.0, 2.0, 2.0, 1.0, 1.0]",Medicine,train,1.6,news,http://ct.moreover.com/?a=33633515198&p=1pl&v=1&x=7XdGBehR5vM4s0x_RvXRiA
10.1038/s41467-018-07418-0,Medicine_574,"""This might initially sound easy, but really is not, since often more than half of the genes we find are so far uncharacterized and unknown.""","We found indications for such plasticity in several bacterial genomes, especially within the Delta-and Gammaproteobacteria that might couple the reduction of sulfur with the oxidation of carbon, lipids or hydrocarbons.","With DNA sequencing and the computer approaches that we use, we're getting closer, and things are expanding quickly."" ""This might initially sound easy, but really is not, since often more than half of the genes we find are so far uncharacterized and unknown."" This is not the end of the study, however, as Baker and the Alvin sampling team have joined to study areas of the basin which haven't been studied before.","Respiratory processes were often partitioned among the community and only few genomes were encoding for full pathways. We found indications for such plasticity in several bacterial genomes, especially within the Delta-and Gammaproteobacteria that might couple the reduction of sulfur with the oxidation of carbon, lipids or hydrocarbons. While we cannot determine which processes are active, enhanced genotypic diversity might provide an additional adaptation strategy to variable environmental conditions.","[1.0, 1.0, 2.0, 1.0, 2.0]",Medicine,train,1.4,news,http://ct.moreover.com/?a=37824353635&p=1pl&v=1&x=g1jsEMKAoFn00ytHkP11Yw
10.1073/pnas.1713880115,Medicine_575,These figures show that the dogs that existed during the Mayan civilization were domesticated and given corn as food.,12's unusual δ 13 C and δ 15 N values (Fig.,"These figures show that the dogs that existed during the Mayan civilization were domesticated and given corn as food. Meanwhile, deer bones exhibited butcher marks, suggesting that they may have been hunted in the wild and are likely not fed with local crops. The cats, including a large one resembling a jaguar, showed isotope characteristics of eating wild plants.","Of the other Preclassic period animals tested in this study, the remaining dogs show consistently elevated δ 13 C values. 12's unusual δ 13 C and δ 15 N values (Fig. 2) indicate it had a unique low-maize, high-protein diet and may have been a hunting dog.","[1.0, 1.0, 1.0, 1.0, 2.0]",Medicine,train,1.2,news,http://ct.moreover.com/?a=33645083227&p=1pl&v=1&x=1mbfWh0JQKhF4z7h-ocIbw
10.1073/pnas.0801268105,Medicine_578,"The key is creating a series of tests and guidelines that check capabilities, instead of using chronological age.",The constraints of our experiments do not permit us to know how much longer we could have continued training before failing to realize any further gains in Gf.,"Since people age differently, a mandatory retirement age for surgeons is unfair, Katlic and Perry say. The key is creating a series of tests and guidelines that check capabilities, instead of using chronological age. ""However, we've learned that a number of physicians have opted to retire when threatened to be put through our program,"" Katlic says.",The dose-responsive gain in Gf indicates that the training benefit is not a threshold phenomenon. The constraints of our experiments do not permit us to know how much longer we could have continued training before failing to realize any further gains in Gf. This dose responsiveness is an important issue for further study because the exact plot of gain with training could have important practical implications for those interested in training fluid intelligence.,"[1.0, 1.0, 3.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.npr.org/sections/health-shots/2015/06/18/414912417/when-should-surgeons-stop-operating
10.1186/s12904-016-0129-0,Medicine_579,"Cox diz que depois que implementou a maconha em seu ritual de luto, seu sono e humor melhoraram.","As this study compared 38 intervention persons with 86 controls, we regard the results as clinically interesting.","Se possivel, fale com um profissional de saude imparcial sobre todo o processo de luto. Cox diz que depois que implementou a maconha em seu ritual de luto, seu sono e humor melhoraram. Isso nao e surpresa, com estudos mostrando que apoio social pode melhorar os resultados do processo de luto.","Our clinical opinion is that if relevant differences in treatment effects are not detected in an intervention group of 10 to 15 persons, in spite of 10 hours counselling with three experienced facilitators, treatments are difficult to motivate as ""value for money"". As this study compared 38 intervention persons with 86 controls, we regard the results as clinically interesting. However, attendance rate was high at meetings so the results may give a reasonable picture.","[1.0, 1.0, 1.0, 2.0]",Medicine,train,1.25,news,http://ct.moreover.com/?a=39052842120&p=1pl&v=1&x=AEwoUDuaCvDghVWkGINUEA
10.1177/0956797617692041,Medicine_58,The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving.,"These concerns, combined with the extant research on the contextual, social, and convenience factors affecting choice, led us to predict that bundling would not backfire and could even reduce sugary-drink purchases.","The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means. The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving. However, it did not affect the further downstream behavior of consumption.","In addition, a strict (although unlikely) implementation limiting sugarydrink sizes to 16 oz decreased the number of hypothetical calories purchased. These concerns, combined with the extant research on the contextual, social, and convenience factors affecting choice, led us to predict that bundling would not backfire and could even reduce sugary-drink purchases. Indeed, that a single unit (i.e., a cup) is considered a more appropriate serving size than the same quantity divided into two serving containers suggests that bundling may decrease purchasing.","[3.0, 3.0, 5.0, 2.0]",Medicine,train,3.25,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1098/rspb.2009.1900,Medicine_580,"The ""watching eyes effect"" makes for fun and easy citizen science.","Therefore, relatively weak forces can affect behaviour in the dictator game.","But you can see for yourself. The ""watching eyes effect"" makes for fun and easy citizen science. The next time you want to induce some ""honest"" behavior, bring along an extra pair of eyes!","A possible reason for this may be that the dictator game constitutes a less robust situation. Therefore, relatively weak forces can affect behaviour in the dictator game. Perhaps the implicit reputation cue is one of these weak forces.","[1.0, 3.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,news,http://www.realclearscience.com/blog/2015/12/the_world_would_be_a_much_better_place_if_there_were_eyes_everywhere.html
10.1101/lm.037291.114,Medicine_581,"So, essentially, your age is actually a measure of chronology, physiology, sociology, and psychology, she says.",It should be mentioned that amygdalar lesions/inactivation blocked stress effects on hippocampal LTP and memory despite the increase in CORT levels (see also .,"Ignore this factor at all costs, she adds. So, essentially, your age is actually a measure of chronology, physiology, sociology, and psychology, she says. ""I would recommend a minimum of 12 to a maximum of 16-hour fasting period between dinner and breakfast,"" she says.","Since immediate, post-stress muscimol infusions into the amygdala failed to prevent stress effects on LTP and memory, it appears the critical time window of amygdalar activity is during, and not after, stress . It should be mentioned that amygdalar lesions/inactivation blocked stress effects on hippocampal LTP and memory despite the increase in CORT levels (see also . These findings suggest that the amygdala is a critical component of the central stress mechanism affecting hippocampal functioning.","[2.0, 1.0, 3.0, 1.0]",Medicine,train,1.75,news,http://ct.moreover.com/?a=38068224339&p=1pl&v=1&x=coI6m_VNBj546f2Li7tAQg
10.1186/s12906-017-2062-z,Medicine_582,Inflammation kan i sin tur visa sig nastan var som helst i kroppen.,"The ESs in the Curamin and CuraMed groups were 5.9-and 5.0-fold higher than in the placebo group, with an ESs of 0.38 (confidence interval, 0.022-0.733) and 0.32 (confidence interval, 0.042-0.679) vs 0.06 (confidence interval, −0.292 -0.419) ( Table 3) .","Halso-samma saker som traning, notter, starka kryddor eller sol i stora mangder kan ocksa bidra till pittaobalans och forsamrad matsmaltning. Inflammation kan i sin tur visa sig nastan var som helst i kroppen. Alla har nagon svaghet, det kan vara huden, musklerna eller lederna.","The walking speed of a 40-m distance significantly increased from week 4 to week 12 of treatment only in the Curamin and CuraMed groups ( Fig. The ESs in the Curamin and CuraMed groups were 5.9-and 5.0-fold higher than in the placebo group, with an ESs of 0.38 (confidence interval, 0.022-0.733) and 0.32 (confidence interval, 0.042-0.679) vs 0.06 (confidence interval, −0.292 -0.419) ( Table 3) . Between-group comparisons of the changes from baseline demonstrated differences in the effect of the intervention compared to placebo.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39102394392&p=1pl&v=1&x=ATQrz5KG2CwdjZHPtq9Mgw
10.1186/s12888-016-1111-3,Medicine_583,One study participant placed birds in his closest social circle.,This finding indicates a therapeutic role beyond that found previously for other long-term conditions.,"The animals also could distract them from their illness, even from severe psychosis. One study participant placed birds in his closest social circle. When he was hearing voices, he said that they ""help me in the sense, you know, I'm not thinking about the voices, I'm just thinking of when I hear the birds singing.""","One element of the intimate relationship with pets was their input as a source of practical illness work, notably in relation to distraction and disruption from negative feelings, emotions and untoward symptoms. This finding indicates a therapeutic role beyond that found previously for other long-term conditions. But if I'm here and I'm having…having problems with voices and that, erm, it does help me in the sense, you know, I'm not thinking about the voices, I'm just thinking of when I hear the birds singing (ID 2, 2 birds, first circle).","[1.0, 4.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://healthmedicinet.com/news/pets-help-people-manage-the-pain-of-serious-mental-illness/
10.1073/pnas.1817205116,Medicine_584,"Due to the accelerated melting of ice, the sea levels could rise faster too, considering that ice sheets on both Greenland and Antarctica are endangered.","The 95th percentile ice sheet contribution by 2200, for the +5°C scenario, is 7.5 m as a result of instabilities coming into play in both West and East Antarctica.","A new study adds to the plethora of evidence suggesting that we need to take action before global sea levels rise drastically, which could happen by the end of the century. Due to the accelerated melting of ice, the sea levels could rise faster too, considering that ice sheets on both Greenland and Antarctica are endangered. That's double the upper limit warned about by the UN climate science panel.","Beyond 2100, uncertainty and projected SLR increase rapidly. The 95th percentile ice sheet contribution by 2200, for the +5°C scenario, is 7.5 m as a result of instabilities coming into play in both West and East Antarctica. Introducing process correlations and tail dependences increases estimates by roughly 15%.","[4.0, 5.0, 2.0, 2.0, 3.0]",Medicine,train,3.2,news,http://ct.moreover.com/?a=39285629267&p=1pl&v=1&x=qjuEVjhrnSTn4j0Ie-u_kA
10.1016/j.cub.2014.11.033,Medicine_585,"However, as the spermathecal cells stretched upon entry of the egg, SPV-1 detached from the straightened membrane.","Taken together, our findings support a model in which SPV-1 regulates cyclical contraction of the spermatheca through transient localization to the apical membrane mediated by its F-BAR domain ( Figure 5C ).","In an empty spermatheca, SPV-1 attached to the folded, convoluted cell membranes where it acted as a protein roadblock preventing actomyosin contractility. However, as the spermathecal cells stretched upon entry of the egg, SPV-1 detached from the straightened membrane. With the roadblock removed, actomyosin contractility occured and a fertilised embryo was ejected into the uterus.","Thus, detachment of SPV-1 from the membrane, facilitated by the F-BAR domain, functions as a cue to initiate spermathecal contractility and embryo exit. Taken together, our findings support a model in which SPV-1 regulates cyclical contraction of the spermatheca through transient localization to the apical membrane mediated by its F-BAR domain ( Figure 5C ). We presume SPV-1 localization to be membrane curvature dependent.","[5.0, 3.0, 2.0, 3.0, 3.0]",Medicine,train,3.2,news,http://www.newswise.com/articles/epithelial-tube-contraction
10.1089/cyber.2014.0317,Medicine_586,It is also related to two socioeconomic factors: GDP per capita and the Internet penetration rate.,The results revealed six extreme outliers in the data set.,"Cheng and Li's work focuses on the prevalence issue, bringing together data for a more conclusive global estimate. It is also related to two socioeconomic factors: GDP per capita and the Internet penetration rate. The results of the study failed to support this hypothesis.","About half (49%) of the participants were men, and the average age was 18.42 years (SD = 5.02; range 12-41). The results revealed six extreme outliers in the data set. The prevalence rates were relatively low for the nations in Oceania and those in Northern and Western Europe, but relatively high for the nations in the Middle East.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.techtimes.com/articles/22541/20141219/internet-addiction-affects-6-percent-of-global-population-study.htm
10.1111/pbi.12661,Medicine_587,"""For cleaning up contaminated soils, grasses work best, but they're definitely not as easy to transform, especially since flexible systems to express multiple genes in grasses have not been used before,"" said first author and acting UW instructor Long Zhang.","After 9 days of culture, lines N5 and 18 also removed significantly more RDX from the media than wild type (P = 0.03 for N5 and 0.05 for N18).","In particular, the UW engineers had to build into their gene constructs robust monocot ""promoters"" -- or regions of DNA that cause a particular gene to be expressed -- for the process to work in grass species. ""For cleaning up contaminated soils, grasses work best, but they're definitely not as easy to transform, especially since flexible systems to express multiple genes in grasses have not been used before,"" said first author and acting UW instructor Long Zhang. The research team also found another unexpected side benefit: because the genetically modified grasses use RDX as a nitrogen source, they actually grow faster than wild grass species.","The RDX removal by line N19 was not only significantly greater than that of wild type, but also greater than lines N5 and N18 (P < 0.05). After 9 days of culture, lines N5 and 18 also removed significantly more RDX from the media than wild type (P = 0.03 for N5 and 0.05 for N18). RDX levels were highest in wild-type creeping bentgrass tissues (Figure 5b ), while lower levels of RDX were detected in plant lines N5 and N18; RDX was not detected in line N19.","[2.0, 4.0, 3.0, 1.0]",Medicine,train,2.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/DUrKXVO_Vac/
10.1038/s41564-019-0367-z,Medicine_588,Researchers can now explain how a cell that is being attacked by bacteria or viruses specifically manages to 'sound the alarm' among its neighboring cells so they can react with a quick response.,"The effect of GW4869 on Ifnb mRNA induction was not due to a general suppressive effect on Ifnb transcription, since Ifnb mRNA levels in the spleen after TLR9 agonist treatment were not affected ( Supplementary Fig.","Researchers can now explain how a cell that is being attacked by bacteria or viruses specifically manages to 'sound the alarm' among its neighboring cells so they can react with a quick response. ""We've succeeded in finding and describing a messenger which both quickly and effectively can inform the surrounding cells that something is very wrong and that the cells must therefore band together to fight the foreign micro-organisms"" says professor Soren Riis Paludan from the Department of Biomedicine at Aarhus University, Denmark. ""The study sheds new light on how the organism quickly and effectively alarms the neighborhood, and now that we know about the mechanism, it makes sense to continue working on when it might be advantageous to give it a boost to inhibit an infection, and vice versa, when it should be blocked in order to halt an autoimmune disease,"" says Nandakumar.","3g ), but not Tnfa mRNA (Fig. The effect of GW4869 on Ifnb mRNA induction was not due to a general suppressive effect on Ifnb transcription, since Ifnb mRNA levels in the spleen after TLR9 agonist treatment were not affected ( Supplementary Fig. Collectively, these results demonstrate that EV-mediated DNA transfer to bystander cells occurs during infection with intracellular bacteria.","[1.0, 3.0, 2.0, 3.0, 4.0]",Medicine,train,2.6,news,http://ct.moreover.com/?a=38639018346&p=1pl&v=1&x=nBHoU4YuRxGM-XtW7LCoJA
10.1038/s41467-019-09961-w,Medicine_589,"Using MRI data, the researchers were able to show how this mechanism works in the brain.","By this process, episodic simulations modify attitudes toward the very elements that the simulations had been based on, thus influencing how we evaluate our real-life environment.","And we don't even have to actually experience the episode in reality,"" is how co-author Daniel Schacter sums it up. Using MRI data, the researchers were able to show how this mechanism works in the brain. But this region also evaluates how important individual people and places are for us.","Such evaluative conditioning forms attitudes by changing the liking of the CS to align with the valence of the UCS . By this process, episodic simulations modify attitudes toward the very elements that the simulations had been based on, thus influencing how we evaluate our real-life environment. Our hypothesis assigns a key role to the vmPFC in mediating such presumed attitude change.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39250492451&p=1pl&v=1&x=6VwLkjOi_emjw_8akjADsA
10.1001/jama.2018.7028,Medicine_59,"When PTSD patients took SSRIs for 179 days or less, however, they had more than triple the risk of autoimmune disorders.","In addition, among patients with PTSD specifically, persistent use of SSRIs throughout the first year after diagnosis was associated with attenuated risk of autoimmune disease.","PTSD patients who took SSRIs for at least 320 days that first year after diagnosis were 82 percent more likely to develop autoimmune disorders than individuals without stress disorders, the study found. When PTSD patients took SSRIs for 179 days or less, however, they had more than triple the risk of autoimmune disorders. Roughly 9 in every 1,000 people diagnosed with stress disorders in the study developed autoimmune disorders each year, researchers calculated.","These associations were independent of history of other psychiatric disorders and became stronger with the presence of co-occurring psychiatric comorbidities. In addition, among patients with PTSD specifically, persistent use of SSRIs throughout the first year after diagnosis was associated with attenuated risk of autoimmune disease. To our knowledge, this is the first study to address all stressrelated disorders and their associations with 41 distinct autoimmune diseases in men and women using both populationand sibling-based comparisons.","[3.0, 5.0, 2.0, 3.0, 3.0]",Medicine,train,3.2,news,http://ct.moreover.com/?a=34345635410&p=1pl&v=1&x=x9tdQB0Ktba3xt_eBoS5xQ
10.1111/acer.13408,Medicine_590,"Before the intervention, says Petrenko, ""parents felt they were often just pulling at straws""--guessing at what might work best.",Adapting existing interventions improves study efficiency and increases the potential for future dissemination.,"""The intervention really helps parents understand their children's behavior and lets them understand why their kids are the way they are."" Before the intervention, says Petrenko, ""parents felt they were often just pulling at straws""--guessing at what might work best. ""After program completion, having been given these tools, they feel more confident in their parenting approach.""","Similar to several prior FASD interventions , results from this study document that existing interventions can be effective for children with FASD with appropriate adaptations. Adapting existing interventions improves study efficiency and increases the potential for future dissemination. Caregivers were also Bold data highlight statistically significant findings.","[1.0, 3.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,news,http://www.futurity.org/intervention-fetal-alcohol-spectrum-disorders-parents-1412692/
10.1126/scisignal.aac5472,Medicine_591,"We need more studies to make sure they were not losing bone or muscle mass.""","Trehalose stimulated an increase in AMPK (Thr 172 ) phosphorylation within 30 min, and this increase was sustained throughout the 4-hour time course (Fig.","""We know the mice that received drinking water with three percent trehalose lost weight, and we suspect that weight loss was due to loss of fat, but we can't be certain that's the only effect. We need more studies to make sure they were not losing bone or muscle mass."" In the meantime, DeBosch advises his patients to avoid foods with added fructose, especially sugar-sweetened beverages.","Reduced ATP concentration should increase the AMP/ATP ratio, leading to the phosphorylation at Thr 172 and activation of AMPK, an energy-sensing kinase that stimulates autophagy . Trehalose stimulated an increase in AMPK (Thr 172 ) phosphorylation within 30 min, and this increase was sustained throughout the 4-hour time course (Fig. In contrast, AMPK activation was at basal levels in cells that had not been exposed to trehalose (0 in Fig.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/8epGo0Xrlqg/
10.1186/s13054-014-0480-6,Medicine_592,"Instead of creating another EMR alert, data should be tethered to a decision support system so treatment is proactive and forecasted, rather than reactive.","This strategy requires that initial antibiotic choices be guided by local antibiotic resistance patterns and laboratory test results (including Gram staining), rapidly yielding identities of likely responsible pathogens.","I get 100 alerts a day,"" Dr. Siddiqui said, adding that the industry needs to do a better job of making EMR data actionable without contributing to clinician alert fatigue. Instead of creating another EMR alert, data should be tethered to a decision support system so treatment is proactive and forecasted, rather than reactive. The decision support solution can analyze EMR data to identify patients at-risk for developing complications down the road so that decisions can be made and communicated faster.","In general, the first goal can be accomplished by rapidly identifying patients with infection and starting empirical therapy likely to treat the institution's most common etiological agents. This strategy requires that initial antibiotic choices be guided by local antibiotic resistance patterns and laboratory test results (including Gram staining), rapidly yielding identities of likely responsible pathogens. Therefore, every effort","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34230514886&p=1pl&v=1&x=sTidMUp-CQ82HZ8HjR4Fgw
10.1093/cercor/bhp008,Medicine_593,"Das heisst nach einer eindringlichen ersten Testphase also konkret: Zum dudeligen Bass kommen nach und nach auch noch andere Bass-Gitarren, die den Sex-Soundtrack rhythmisch upgraden sollen.",An additional notable effect of valence was found in the substantia nigra.,"Die ernuchternde Antwort: Die App passt lediglich den Rhythmus dieses einen Songs an. Das heisst nach einer eindringlichen ersten Testphase also konkret: Zum dudeligen Bass kommen nach und nach auch noch andere Bass-Gitarren, die den Sex-Soundtrack rhythmisch upgraden sollen. Entsprechend steigert er die Geschwindigkeit.","An area of overlap between familiarity and valence responses was in the ventral lateral thalamic nucleus. An additional notable effect of valence was found in the substantia nigra. As noted above in the Materials and Methods, the familiarity, autobiographical salience, and valence regressors were correlated moderately prior to orthogonalization ( Supplementary  Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=33839584826&p=1pl&v=1&x=5ADwEoil4iW7ttlnMQrtQA
10.1016/j.annemergmed.2018.06.042,Medicine_594,"Making sure everyone can hear you, understand you, and is physically able to follow safety procedures will speed the decontamination process and limit toxic exposure, especially for children, the elderly and the most vulnerable victims,"" said Robert P. Chilcott, PhD, professor at the University of Hertfordshire (UK) and lead study author.","A ladder pipe operator stated that ""It was pretty tough keeping those people in really cold water, but usually we were able to communicate with the guys standing on the end of it demonstrating to make sure you catch as much of your body as you can.","""Should a large-scale chemical exposure occur, clear communication from first responders can save lives. Making sure everyone can hear you, understand you, and is physically able to follow safety procedures will speed the decontamination process and limit toxic exposure, especially for children, the elderly and the most vulnerable victims,"" said Robert P. Chilcott, PhD, professor at the University of Hertfordshire (UK) and lead study author. ""First responder staffing levels and resources may need to be re-evaluated in order to avoid casualties and ensure safe and effective rapid response.""","It was noted that the wound dressing packs had been difficult to distribute and that firefighters wearing full personal protective equipment had needed to intervene by picking up dressing packs from the floor to hand to the volunteers. A ladder pipe operator stated that ""It was pretty tough keeping those people in really cold water, but usually we were able to communicate with the guys standing on the end of it demonstrating to make sure you catch as much of your body as you can. Having a facecloth would have been really useful.""","[2.0, 2.0, 2.0, 1.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34969890416&p=1pl&v=1&x=uZ-qm2MubdaW8Fvq03jOmA
10.1016/j.stemcr.2014.02.010,Medicine_595,"As they suspected, when cells lacked GRP78 on their surfaces, they didn't respond to CRIPTO.","Significantly, the self-renewal potential of these cells is evident in their capacity to reconstitute fully arborized mammary epithelial outgrowths in tertiary transplants that respond normally to pregnancy ( Figure S4G ).","When they instead boosted levels of CRIPTO, the stem cell colony grew as new stem cells were produced more often than differentiated cells. As they suspected, when cells lacked GRP78 on their surfaces, they didn't respond to CRIPTO. With the new ability to isolate and sustain mammary stem cells, Spike and Gray hope they can uncover details on exactly what cellular programs CRIPTO and GRP78 activate.","Outgrowths from transplanted GRP78 high cells resemble endogenous mammary glands in FACS analyses including the presence of GRP78 high cells within the CD24 expressing mammary epithelium ( Figure S4F) . Significantly, the self-renewal potential of these cells is evident in their capacity to reconstitute fully arborized mammary epithelial outgrowths in tertiary transplants that respond normally to pregnancy ( Figure S4G ). We also identify a diffuse, small, and variable population of GRP78 ''superpositive'' (GRP78 high+ ) cells with intermediate performance in stem cell assays ( Figures  S4D and S4E) .","[1.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.4,news,http://www.sciencedaily.com/releases/2014/05/140507100434.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10533-018-0502-6,Medicine_597,"The downstream data showed an instant spike in copper released from the streambed, suggesting a direct connection between the stream's salt content and copper in the water.","For example, NO 3 -, DOC, and turbidity dynamics all b Fig.","In a similar set of observations in Washington, D.C.'s Rock Creek, the team observed notable spikes in cadmium, copper and zinc following other snowstorms. The downstream data showed an instant spike in copper released from the streambed, suggesting a direct connection between the stream's salt content and copper in the water. Salt ion concentrations can stay high for months following a storm, Kaushal added.","Developing a unified concept for chemical transport in catchments in response to hydrological events Analyzing how chemical cocktails respond similarly or differently over time can allow us to formulate a unified concept for catchment chemical transport in response to hydrologic events (e.g., based on common modes of transport, mobility, and reactivity for carbon, nutrients, redox sensitive metals, and ionic salts). For example, NO 3 -, DOC, and turbidity dynamics all b Fig. 9 There have been significant changes in sieved, EEA 2012; Jaworski, unpublished data; .","[1.0, 3.0, 1.0, 1.0]",Medicine,train,1.5,news,http://ct.moreover.com/?a=37871057373&p=1pl&v=1&x=AqaJhGfZgLtEdz5q-Bzr2Q
10.1073/pnas.1308285110,Medicine_598,"It's very hard to change people's minds, to convince people about life after death or not.","In contrast, the CAS3 period was distinguished by a clear increase in absolute power of low gamma ( Fig.","Will this study convince people, one way or the other, about the existence of life after death? It's very hard to change people's minds, to convince people about life after death or not. Are you planning further experiments to follow up?","A short burst of delta (0-5 Hz) waves separated the CAS2 and CAS3 periods and was associated with abruptly reduced beta and low-gamma (25-55 Hz) power. In contrast, the CAS3 period was distinguished by a clear increase in absolute power of low gamma ( Fig. During this period, all other bands showed further decline in power.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://news.nationalgeographic.com/news/2013/08/130814-near-death-brain-life-after-death-bright-light/
10.1001/jamasurg.2014.2253,Medicine_6,"Our findings indicate potential overuse of PTR among these patients and highlight a need to better understand the clinical decisions and outcomes associated with that treatment,"" the authors conclude.",The use of PTR varied significantly according to both the demographic characteristics of the patients and clinical factors.,"The authors acknowledge limitations of their study, including that the decreasing rate of PTR could have primarily been the result of more effective systemic therapy or of greater reluctance by surgeons to operate on patients with asymptomatic stage IV CRC. ""Despite the availability of more effective chemotherapeutic options, a considerable number of patients with stage IV CRC continue to undergo PTR. Our findings indicate potential overuse of PTR among these patients and highlight a need to better understand the clinical decisions and outcomes associated with that treatment,"" the authors conclude.","Our population-based study demonstrated that the use of PTR in patients presenting with stage IV CRC has been decreasing over time, and a notable reduction in the PTR rate was observed in 2001. The use of PTR varied significantly according to both the demographic characteristics of the patients and clinical factors. Younger age, female sex, white race/ ethnicity, married status, residence in the South, higher tumor grade, and tumors located in the colon were associated with an increased likelihood of having undergone PTR.","[2.0, 4.0, 2.0, 1.0, 2.0]",Medicine,train,2.2,news,http://www.sciencedaily.com/releases/2015/01/150114115508.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41467-018-04355-w,Medicine_60,"""These results shed new light on tumor microenvironment functioning and, potentially, may lead to new approaches for targeting the metastases of this extremely aggressive disease,"" said Alessandro Porrello, PhD, researcher at UNC Lineberger and the study's first author.","By integrating multi-step genomics analyses with novel mouse models, we found that IMs are critical drivers of LUSC metastasis.","""It's important to understand that while there is so much focus on activating parts of the immune system to attack cancer, there is also a 'Jekyll and Hyde' process going on in most tumors,"" Pecot said. ""These results shed new light on tumor microenvironment functioning and, potentially, may lead to new approaches for targeting the metastases of this extremely aggressive disease,"" said Alessandro Porrello, PhD, researcher at UNC Lineberger and the study's first author. By genetically modifying the expression of CCL2 in a metastasis model developed in their laboratory, they found low expression was linked to reduced metastases, while high expression was linked to enhanced metastatic features.","Discussion PD1/PD-L1 immune checkpoint inhibitors, while effective in several cancer types, provide only about 20% response rates in unselected LUSC patients 5 . By integrating multi-step genomics analyses with novel mouse models, we found that IMs are critical drivers of LUSC metastasis. This analysis clearly implicated CD14 and the IM-rich subset in the poor survival of LUSC patients.","[1.0, 3.0, 1.0, 1.0, 2.0]",Medicine,train,1.6,news,http://healthmedicinet.com/news/by-forming-clots-in-tumors-immune-cell-aids-lung-cancers-spread/
10.1177/1088868313497266,Medicine_600,"The 400% increase in atheism is a stunning number, especially from a country with such a long history of religiosity and problems stemming from the tension between Protestants and Catholics.","The omnibus F was significant, F(3, 54) = 7.06, p < .001.","Hegarty also points out that the Catholic Church influences basically ""everything"" in Ireland, including government and education. The 400% increase in atheism is a stunning number, especially from a country with such a long history of religiosity and problems stemming from the tension between Protestants and Catholics. Hegarty also points out a trend toward ""cultural Catholicism"" in which people participate in the celebrations and rituals of the Catholic Church without actually believing in a personal God, and he says this trend is also on the rise.","Any effects that distorted the ""true"" intelligence-religiosity relation should be removed. The omnibus F was significant, F(3, 54) = 7.06, p < .001. Surprisingly, studies with restriction of range yielded an effect size (M = −.31) that was more negative than that of the 46 studies with no evident source of bias (M = −.14).","[3.0, 4.0, 1.0, 2.0, 1.0]",Medicine,train,2.2,news,http://guardianlv.com/2014/01/ireland-turning-atheist/
10.1016/j.eplepsyres.2018.10.003,Medicine_601,"The study, led by Irazoqui's team at Purdue, found acid in the esophagus of animal models 100 percent of the time that they experienced sudden death during a seizure.",In one case the lag between electrodes was < 5 s.,"Sitting up pushes the acid back down to the stomach with the help of gravity. The study, led by Irazoqui's team at Purdue, found acid in the esophagus of animal models 100 percent of the time that they experienced sudden death during a seizure. These findings propose another potential cause of death to investigate, as well as ideas for more targeted treatment.","In two cases the pH change occurred in < 10 s. In six animals in which there was a pH change and two recording electrodes, the average delay between the pH change on the electrodes was 15.2  18 min. In one case the lag between electrodes was < 5 s. Three times after death we observed a pool of liquid at the animal's mouth, which was never present in control animals (Figure 6a ).","[1.0, 1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=38210522649&p=1pl&v=1&x=GtiFUzqWGcBfarbO3gmxSQ
10.1093/scan/nsu039,Medicine_602,"Once you immerse yourself in other details, your mind will wander to something else entirely, and you won't be focused on the negative emotions as much.""",This procedure allowed identification of the brain regions that showed increased activation in both conditions.,"""But we found that instead of thinking about your emotions during a negative memory, looking away from the worst emotions and thinking about the context, like a friend who was there, what the weather was like, or anything else non-emotional that was part of the memory, will rather effortlessly take your mind away from the unwanted emotions associated with that memory. Once you immerse yourself in other details, your mind will wander to something else entirely, and you won't be focused on the negative emotions as much."" This simple strategy, the study suggests, is a promising alternative to other emotion-regulation strategies, like suppression or reappraisal.","[Context vs SM] \ [Emotion vs SM]), in which the statistical activations maps of the two contributing contrasts (Context vs SM) and (Emotion vs SM) were inclusively masked with each other. This procedure allowed identification of the brain regions that showed increased activation in both conditions. Context vs SM and Emotion vs SM, respectively).","[1.0, 1.0, 1.0, 2.0]",Medicine,train,1.25,news,http://www.sciencedaily.com/releases/2014/04/140418141121.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.3758/s13420-015-0194-x,Medicine_603,"And now they completely ignore social information and they just use trial and error learning to open the door and extract the food,"" Logan explained.","Whilst the task did not involve tool making, we assume that any social learning mechanism found to play a role in the acquisition of novel foraging behavior is also likely to play a role in the acquisition of tool-making behavior.","But the researchers did strong evidence of social learning: if one crow sees a companion interacting with a particular area of the apparatus, reaching its bill through a door and pulling out a piece of boiled egg - the treat - the former is far more likely to try that particular door on either apparatus before choosing the other access options. And now they completely ignore social information and they just use trial and error learning to open the door and extract the food,"" Logan explained. Even if one crow is at an apparatus and tries unsuccessfully to open the door, if he or she sees another crow on the second apparatus actually solving the problem correctly, the first crow doesn't use that information.","We found no evidence that the choice of apparatus was influenced by the apparatus at which the interactions of others were observed suggesting the context specific effect generalized between apparatuses, as would be expected by stimulus enhancement, but not local Fig. Whilst the task did not involve tool making, we assume that any social learning mechanism found to play a role in the acquisition of novel foraging behavior is also likely to play a role in the acquisition of tool-making behavior. Since action-specific social learning mechanisms (e.g., imitation or emulation) would be required to account for the documented pattern of variation in New Caledonian crow tool types, that we found no action-specific effect in our diffusion experiment suggests that social learning resulting from observing another's tool-making activity is unlikely to explain tool type variation.","[1.0, 2.0, 2.0, 4.0, 1.0]",Medicine,train,2.0,news,http://www.sci-news.com/biology/science-new-caledonian-crows-corvus-moneduloides-social-learning-03219.html
10.1073/pnas.1308939110,Medicine_604,"He went on to say, ""Just because a plant or animal trait is common today doesn't mean that it was bred into them from the beginning.","While the expression of the dominant allele in skin tissue results in white skin color, the recessive allele possesses one or more cis-acting and tissue-specific regulatory mutations that inhibit expression of BCDO2 in skin tissue.","In fact, it probably only became prevalent in domesticated chickens as late as 500 years ago. He went on to say, ""Just because a plant or animal trait is common today doesn't mean that it was bred into them from the beginning. It demonstrates that the pets and livestock we know today-dogs, chickens, horses, cows-are probably radically different from the ones our great-great-grandparents knew.""","As a result, a re-evaluation of all the early finds is necessary to establish the chronology and geography of chicken domestication. While the expression of the dominant allele in skin tissue results in white skin color, the recessive allele possesses one or more cis-acting and tissue-specific regulatory mutations that inhibit expression of BCDO2 in skin tissue. Provided that sufficient carotenoids are available in the diet, the recessive allele reduces carotenoid cleavage and allows them to be deposited in skin tissue leading to yellow skin .","[2.0, 1.0, 2.0, 1.0, 2.0]",Medicine,train,1.6,news,http://www.scienceworldreport.com/articles/14144/20140422/evolution-barnyard-chicken-ancient-bone-dna-reveals-rapid-changes.htm
10.1111/ecoj.12256,Medicine_605,But it then reverses direction and keeps rising to the age of 70.,The average age in the MABEL sample is slightly higher at 45.4 years (11.7).,"But don't worry, it doesn't last. But it then reverses direction and keeps rising to the age of 70. The findings show there really is a kind of midlife ""crisis"" in people's feelings of satisfaction with their lives.","The average (standard deviation) age of subjects in these data sets is 40.9 years (15.0) for the BHPS, 39.4 years (14.8) for HILDA and 40.5 years (14.5) for SOEP. The average age in the MABEL sample is slightly higher at 45.4 years (11.7). In the eyes of some researchers, particularly those from a psychology background, the single-item nature of our analysis is not necessarily ideal.","[1.0, 1.0, 2.0, 2.0]",Medicine,train,1.5,news,http://www.futurity.org/midlife-happiness-aging-1055032/
10.1177/1742395311429393,Medicine_606,Hyland told SELF that the treatments required her to be hooked up to a machine through a port in her chest.,"[] Finally, anticipated stigma from healthcare providers may be associated with decreased patient satisfaction among people living with chronic illness.","Unfortunately, though, by October 2016, Hylandas body had started to reject the kidney, and, as per SELF, the then-25-year-oldas creatinine levels (aka waste that would normally be flushed out by your kidneys, the outlet explains) were considerably high. Hyland told SELF that the treatments required her to be hooked up to a machine through a port in her chest. As a result of the dialysis, Hyland said she lost a significant amount of weight, developed sciatica (severe lower back pain), experienced swelling in the face, and a spike in blood pressure that affected her vision.","Although not all chronic illnesses are concealable, people living with chronic illnesses who anticipate stigma may likewise be more likely to socially isolate themselves and therefore receive less social support. [] Finally, anticipated stigma from healthcare providers may be associated with decreased patient satisfaction among people living with chronic illness. People living with chronic illness who anticipate stigma from their healthcare providers may be less open about their symptoms and illness-related concerns with their healthcare providers.","[1.0, 3.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,news,http://ct.moreover.com/?a=37953358997&p=1pl&v=1&x=Nd2HoaAt80ZWni3RqJtbgg
10.1242/jeb.128165,Medicine_607,"With some forward planning, it's easy to swap red meat for other animal products and non-meat alternatives that are healthier and more environmentally sustainable.",4A-C) : the macropod measurements were higher than expected for nonruminants but lower than in ruminants.,"Alternatively, a handful of dried shiitake mushrooms in your salad or stir-fry would fulfil your requirements. By making some of the changes above and increasing your intake of meat alternatives such as legumes, you'll also be boosting your levels of dietary fibre. With some forward planning, it's easy to swap red meat for other animal products and non-meat alternatives that are healthier and more environmentally sustainable.","However, CH 4 yield of M. fuliginosus and M. rufus per unit of DMI, GEI and dNDFi as well as related to body mass shows a different picture (Fig. 4A-C) : the macropod measurements were higher than expected for nonruminants but lower than in ruminants. The results facilitate a comparison with other herbivores that suggests that CH 4 production in macropods is not fundamentally different from that in other mammals, but is similarly low to that in, for example, horses when compared with ruminants, and lead to a hypothetical explanation for why physiological characteristics of macropods could be responsible for these low values.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=39441990364&p=1pl&v=1&x=YxAD5qU8KM3Gmd7EgOopCA
10.1038/s41598-017-00981-4,Medicine_608,"Coated with platinum powder, each nanoelectrode has a rough surface texture, which improves its ability to pass signals.","6d for ±100 mV), whereas, if the shape of the postsynaptic signals presumably originated from multiple PSPs (as in Fig.","""Our combination of the sensitivity and parallelism can benefit fundamental and applied neurobiology alike, including functional connectome construction and high-throughput electrophysiological screening,"" said Hongkun Park, PhD, the Mark Hyman Jr. professor of chemistry and professor of physics, and co-senior author of the paper. ""The mapping of the biological synaptic network enabled by this long sought-after parallelization of intracellular recording also can provide a new strategy for machine intelligence to build next-generation artificial neural network and neuromorphic processors,"" added Donhee Ham, the Gordon McKay professor of applied physics and electrical engineering at the John A. Paulson School of Engineering and Applied Sciences (SEAS), and co-senior author of the paper. Coated with platinum powder, each nanoelectrode has a rough surface texture, which improves its ability to pass signals.","The number of synaptic connections mapped with this approach is summarized in Table 1 for eight patched cells. 6d for ±100 mV), whereas, if the shape of the postsynaptic signals presumably originated from multiple PSPs (as in Fig. The summary in Table 1 illustrates the variations in connectivity between the different cell cultures and patched neurons.","[1.0, 2.0, 2.0, 3.0, 1.0]",Medicine,train,1.8,news,http://ct.moreover.com/?a=40268623864&p=1pl&v=1&x=GnMfq6uP6rJXVXPwSsrPIg
10.1111/cdev.12250,Medicine_62,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","Alternatively, these teens may actually be later selecting partners as adults who are similar to themselves in terms of status-seeking behavior, and may thus find that their partners actually are ending relationships with them due to status concerns.","By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","These teens may then be likely to perceive social status as a primary reason for the formation or dissolution of important relationships (e.g., romantic relationships) going forward, whether or not this is actually the case. Alternatively, these teens may actually be later selecting partners as adults who are similar to themselves in terms of status-seeking behavior, and may thus find that their partners actually are ending relationships with them due to status concerns. In either case, these findings make clear that the status-seeking aspect of early adolescent pseudomature behavior displays long-term continuity that extends into a new and important relationship domain even across a span of nearly a decade.","[5.0, 4.0, 2.0, 2.0, 2.0]",Medicine,train,2.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1002/ijc.28956,Medicine_63,"""However the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas were already more than 1 mm thick when diagnosed,"" Professor Green said.",As seen across all ages those diagnosed with lesions >1 mm were at higher risk of death of those with thin melanoma.,"As expected in the state's sunny climate, young Queenslanders are still up to five times more likely to be diagnosed with melanoma than young people in the US or Europe. ""However the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas were already more than 1 mm thick when diagnosed,"" Professor Green said. ""This generally favourable outcome is likely due, in large part, to early detection, resulting from increased skin cancer awareness.""","With regard to survival, Queensland melanoma patients in this young age group had virtually the same survival rate at around 96% as all Australians aged 0-19, 20- and 0-9 years from 199 to 200 and young adults aged 20-2 years in the USA, and better survival at 5 years than seen in Australians aged 60-69 (91%). As seen across all ages those diagnosed with lesions >1 mm were at higher risk of death of those with thin melanoma. The generally favourable outcome in Queensland is likely due in part to early detection resulting from increased skin cancer awareness.","[4.0, 4.0, 4.0, 4.0]",Medicine,train,4.0,news,http://www.healthcanal.com/cancers/skin-cancer/51127-melanoma-rates-dropping-in-young-queenslanders.html
10.1111/1365-2656.12871,Medicine_64,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.",The transition probabilities between the different disease states can be,"""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","Specifically, the categories for η DZ were (i) all individuals <90 days old, including η RHD = ""maternal antibodies"" AND/OR η MYXV = ""antibodies against MYXV"", (ii) η RHD = ""susceptible"" AND η MYXV = ""susceptible"" (individuals ≥90 days old), (iii) η RHD = ""susceptible"" AND η MYXV = ""immune"" (individuals ≥90 days old), (iv) η RHD = ""immune"" AND η MYXV = ""susceptible"" (individuals ≥90 days old) and (v) η RHD = ""immune"" AND η MYXV = ""immune"" (individuals ≥90 days old). The transition probabilities between the different disease states can be In the case of RHD, the equation was as follows:","[1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1001/jamapsychiatry.2018.1941,Medicine_65,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,"D, The mediation implemented by functional connectivity from the depressive problems score on poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] score; β = 0.0139; P < .001).","In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","3 77 ; P < .001; left middle cingulate and paracingulate gyri: r =0 .38 5;P < .001; left precuneus: r = 0.430; P < .001; left insula: r = 0.348; P < .001; and to 2 ROIs within the right middle cingulate and paracingulate gyri: r = 0.368 and r = 0.402; P < .001 for both), 7 links involving the anterior cingulate cortex (to the left supplementary motor area: r = 0.446; P < .001; right postcentral gyrus: r = 0.368; P < .001; temporal pole [middle temporal gyrus]: r = 0.338; Depression score D, The mediation implemented by functional connectivity from the depressive problems score on poor sleep quality (Pittsburgh Sleep Quality Index [PSQI] score; β = 0.0139; P < .001). The total assocation of the Depressive Problems score with the outcome shows that the regression coefficient 32 (β) of the Depressive Problems score on the PSQI score was high when the functional connectivities were not taken into account.","[4.0, 3.0, 3.0]",Medicine,train,3.333333333333333,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1186/s13578-015-0003-4,Medicine_66,"We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts.","Taken together, our results indicated that aging rat hearts suffered from I/R injury and PC did not improve this injury.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3b in the aging rat hearts. We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","PC did not change the above mentioned indexes in comparison with the I/R (Figures 3, 4, 5 and 6 ). Taken together, our results indicated that aging rat hearts suffered from I/R injury and PC did not improve this injury. H 2 S produced by CSE in cardiovascular system acted as a physiological cardiac function regulator, which protected the cardiac function in ischemic reperfusion or hypoxia .","[3.0, 4.0, 3.0, 5.0]",Medicine,train,3.75,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.4049/jimmunol.1800107,Medicine_67,"Importantly, chemical inhibition and small interfering RNA (siRNA) knock-down of NLRP3 in primary human macrophages reduced IL-1B production in response to CLCs, suggesting that the inflammatory response occurs via the NLRP3 inflammasome pathway.",CLC-induced IL-1β in macrophages occurred through the activation of caspase-1 following the assembly of the NLRP3 inflammasome.,"Additionally, CLCs were shown to promote inflammation in vivo, as evidenced by an increased tissue presence of IL-1b. Importantly, chemical inhibition and small interfering RNA (siRNA) knock-down of NLRP3 in primary human macrophages reduced IL-1B production in response to CLCs, suggesting that the inflammatory response occurs via the NLRP3 inflammasome pathway. However, until recently, they were believed to be inert by-products of eosinophil activity with no immune activation,"" says Eicke Latz, M.D., Ph.D. ""This study suggests that degradation of eosinophils leaves behind remnants that sustain immune activity.","Here we show that CLCs are promptly phagocytosed in vitro by human macrophages, and this leads to the release of the pro-inflammatory cytokine IL-1β. CLC-induced IL-1β in macrophages occurred through the activation of caspase-1 following the assembly of the NLRP3 inflammasome. Furthermore, we show that CLCs promoted inflammation in vivo, characterized by neutrophil infiltration, phagocytosis of the crystals, and IL-1β release.","[3.0, 4.0, 3.0, 3.0, 5.0]",Medicine,train,3.6,news,http://ct.moreover.com/?a=38014682083&p=1pl&v=1&x=fA9J7idoQjbuZC8wnt8o2Q
10.1186/1471-2431-13-162,Medicine_68,The results show high levels of aluminium in each of the 30 infant formulas.,This issue can only be resolved through future research on infant exposure to aluminium through formula feeds and other routes.,"The results show high levels of aluminium in each of the 30 infant formulas. Professor Exley said: ""Clearly the manufacturers of infant formulas are not concerned about reducing their content of aluminium and the extensive use of aluminium-based packaging for infant formulas seems to confirm this. ""There are no adequate criteria upon which to base a safety level for aluminium in infant formulas and for this reason it would be sensible to take action to reduce the level of aluminium to a lowest practicable level.","However, these organisations, charged with the responsibility of protecting the public from additives in their food, need to recognise and emphasise that this value was determined for adults and, critically, it was not based upon any studies on humans, whether infants, adolescents or adults. This issue can only be resolved through future research on infant exposure to aluminium through formula feeds and other routes. However, precautionary practical solutions to this public health issue should now be sought.","[1.0, 4.0, 3.0, 2.0, 2.0]",Medicine,train,2.4,news,http://www.healthcanal.com/child-health/43790-action-needed-now-to-lower-the-content-of-aluminium-in-infant-formulas.html
10.3945/an.111.000513,Medicine_7,"However, the study found that you can significantly lower your risk for cardiovascular disease by eating fresh fruit, including apples.","In men, the risk reduction was 19% in the group consuming >54 g compared to no apple intake .","And a probiotic-rich diet supports diverse gut microbiome, which can potentially protect you from cardiac conditions and autoimmune diseases, among other benefits that scientists are still uncovering. However, the study found that you can significantly lower your risk for cardiovascular disease by eating fresh fruit, including apples. Apples Lower Cholesterol Shutterstock You probably don't spending much time thinking about cholesterol because it's something only older folks need to worry about, right?","A group of Finnish women consuming >71 g of apple/d experienced a 43% reduction in coronary mortality compared to women who did not eat apples. In men, the risk reduction was 19% in the group consuming >54 g compared to no apple intake . These findings were consistent with prior data showing reduced coronary mortality in elderly Dutch men (65-84 y) who consumed apples (average 69 g/d) compared to men who had little or no apple intake .","[3.0, 4.0, 4.0, 4.0, 5.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=40250485393&p=1pl&v=1&x=uqRXZJPaxyAilrC1dCICVA
10.1186/1471-2431-13-162,Medicine_70,"""Since manufacturers are not willing to address the aluminium content of infant formulas it must now be time for the government, through the Food Standards Agency, to provide guidance on this matter and to indicate a maximum allowable concentration, for example, 50 ppb (50 mg/L) aluminium in the product at point of use, as a precautionary step to protect infants against chronic aluminium intoxication during the earliest weeks, months and years of their lives.""",It is the opinion of the authors that regulatory and other nonvoluntary methods are now required to reduce the aluminium content of infant formulas and thereby protect infants from chronic exposure to dietary aluminium.,"Professor Exley said: ""Clearly the manufacturers of infant formulas are not concerned about reducing their content of aluminium and the extensive use of aluminium-based packaging for infant formulas seems to confirm this. ""There are no adequate criteria upon which to base a safety level for aluminium in infant formulas and for this reason it would be sensible to take action to reduce the level of aluminium to a lowest practicable level. ""Since manufacturers are not willing to address the aluminium content of infant formulas it must now be time for the government, through the Food Standards Agency, to provide guidance on this matter and to indicate a maximum allowable concentration, for example, 50 ppb (50 mg/L) aluminium in the product at point of use, as a precautionary step to protect infants against chronic aluminium intoxication during the earliest weeks, months and years of their lives.""","There was no clear evidence that subsequent to the problem of aluminium being highlighted in a previous publication in this journal that contamination had been addressed and reduced. It is the opinion of the authors that regulatory and other nonvoluntary methods are now required to reduce the aluminium content of infant formulas and thereby protect infants from chronic exposure to dietary aluminium. However, the range of values obtained was skewed towards high content and we were left to conclude that the aluminium content of infant formulas were too high, for example as compared to aluminium exposure through breast milk .","[4.0, 4.0, 4.0, 4.0, 3.0]",Medicine,train,3.8,news,http://www.healthcanal.com/child-health/43790-action-needed-now-to-lower-the-content-of-aluminium-in-infant-formulas.html
10.1111/jgs.15671,Medicine_72,The nurse practice environment was the best predictor of poor-quality end-of-life care.,The best predictor of poor quality was the nurse practice environment.,"The researchers found that 58 percent of nurses gave their hospitals an unfavorable evaluation of end-of-life care overall and 53 percent reported that patients often experience painful procedures that were unlikely to change their outcome. The nurse practice environment was the best predictor of poor-quality end-of-life care. Compared to nurses in poor-quality environments, nurses in the best environments were less likely to rate their hospital's overall end-of-life care quality unfavorably (odds ratio, 0.45).",The best predictor of poor quality was the nurse practice environment. Nurses in the best environments were 55% less likely than nurses in poor environments to rate their hospital's overall end-oflife care quality unfavorably (odds ratio = 0.45; 95% confidence interval = 0.39-0.52; P < .001). CONCLUSION: Quality of end-of-life care in US hospitals is imperfect and is significantly worse in hospitals with poor nurse practice environments than in hospitals with the best environments.,"[5.0, 4.0, 5.0]",Medicine,train,4.666666666666667,news,http://ct.moreover.com/?a=38083013721&p=1pl&v=1&x=ehR_OuxwwqRLFfruA-gOJQ
10.1001/jama.2018.20578,Medicine_73,No effect was seen with aspirin on new cancer diagnoses or deaths.,"In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.","Aspirin use was associated with a 43% of major bleeding events, compared to those who did not take it. No effect was seen with aspirin on new cancer diagnoses or deaths. Lead author, Dr Sean Zheng, Academic Clinical Fellow in Cardiology at King's College London said: ""This study demonstrates that there is insufficient evidence to recommend routine aspirin use in the prevention of heart attacks, strokes and cardiovascular deaths in people without cardiovascular disease.","19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[2.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,news,https://www.sciencedaily.com/releases/2019/01/190122114950.htm
10.1001/jamapsychiatry.2018.1941,Medicine_74,"From the other side, people with insomnia also have a higher risk of depression and anxiety.","Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig.","""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" From the other side, people with insomnia also have a higher risk of depression and anxiety. While this particular study found strong neural connections in the association of depressive problems with poor sleep quality, rather than the other way around, in general the effects can work both ways.","In the reverse direction, only 2 links significantly mediated effects of sleep quality on depressive problems with FDR correction. Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig. S4 ) than for the effect in the opposite direction described above.","[2.0, 3.0, 1.0, 1.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1177/0141076814565942,Medicine_75,The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases.","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","Among boys in Muslim families, risk of hyperkinetic disorder did not depend on the boys' foreskin status (HR ¼ 1.08; 95% CI: 0.77-1.52). However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases. Associations of ritual circumcision with risk of asthma were consistently negative, both in the 0-4 years (HR ¼ 0.91; 95% CI: 0.78-1.06) and the 5-9 years age interval (HR ¼ 1.16; 95% CI: 0.89-1.51), yielding an inconspicuous overall HR estimate (HR ¼ 0.96; 95% CI: 0.84-1.10) based on a total of 235 cases of asthma in circumcised boys versus 29,002 cases in intact boys.","[2.0, 4.0, 5.0]",Medicine,train,5.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1038/s41467-018-04408-0,Medicine_76,"If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent.","In the present study, we found that serum BAFF levels were higher in female compared to male mice, which is in accordance with a previous report of sex differences in BAFF levels among wild-type controls .","After numerous experiments on mice and studies of blood samples from 128 men, the researchers were able to conclude that the critical connection is the protein BAFF, which makes the B cells more viable. If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent. Recognition of the link between testosterone and BAFF is completely new.","Interestingly, both hormones suppress bone marrow B lymphopoiesis but differ in their effects on splenic B cell number and BAFF. In the present study, we found that serum BAFF levels were higher in female compared to male mice, which is in accordance with a previous report of sex differences in BAFF levels among wild-type controls . We further found that testosterone suppresses BAFF, and others have shown that estradiol increases Baff mRNA levels and the relative number of mature B cells in the spleen .","[2.0, 3.0, 3.0, 2.0, 1.0]",Medicine,train,2.2,news,http://ct.moreover.com/?a=34228585539&p=1pl&v=1&x=jeRWiJSUImhYEA135bTOfw
10.1152/ajpregu.00204.2013,Medicine_77,"Importance of the Findings The study, according to Dr. Smith, confirms for the first time in vivo that CO has a beneficial effect at the placental level.",This adaptive angiogenesis was similar to our findings.,"Compared to controls, CO exposure did lead to increased vessel diameter, a significant increase in the number of radial artery branches, and significantly higher maternal blood flow. Importance of the Findings The study, according to Dr. Smith, confirms for the first time in vivo that CO has a beneficial effect at the placental level. It also provides an explanation for the lower incidence of PE among smokers, whose CO levels are higher.","The placentas of women who smoke in pregnancy have been reported as larger in size, with an increase in branching of the vascular tree ; the authors suggest that this alteration is an adaptation response, increasing surface area for nutrient transfer. This adaptive angiogenesis was similar to our findings. It is clear that CO plays a role in angiogenesis, a process necessary for placentation and may account for the COinduced increases of placental vessel branching in the placentas of women who smoke in pregnancy.","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,news,http://www.sciencedaily.com/releases/2013/09/130919154253.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.ejca.2017.11.022,Medicine_78,The correlation between eating chicken and a lower risk of breast cancer may have more to do with consuming large quantities of red meat than it does with chicken having any protective qualities.,"Of the eleven cohort studies, ten reported the association between red meat consumption and overall risk of breast cancer; of these, six also reported results separately for pre-menopausal and post-menopausal breast cancer.","As with all observational studies, this research cannot show cause and effect. The correlation between eating chicken and a lower risk of breast cancer may have more to do with consuming large quantities of red meat than it does with chicken having any protective qualities. Some 1,536 cases of invasive breast cancer were diagnosed among the cohort over the eight-year period.","A further five studies were excluded due to repeat analyses conducted on the same cohort and two due to inadequate exposure information; resulting in ten eligible cohort studies in addition to UK Biobank ( Figure 1) . Of the eleven cohort studies, ten reported the association between red meat consumption and overall risk of breast cancer; of these, six also reported results separately for pre-menopausal and post-menopausal breast cancer. The ten studies produced a pooled relative risk for breast cancer, overall, of 1.03 (95% CI 0.99-1.08) (Figure 2 ).","[3.0, 4.0, 3.0, 2.0, 2.0]",Medicine,train,2.8,news,http://ct.moreover.com/?a=40018041593&p=1pl&v=1&x=0-S1_nh44txdcV7SbNzZRw
10.1001/jamapediatrics.2018.0302,Medicine_79,"Taking vitamin D during pregnancy was safe, with no extra fetal or neonatal mortality, congenital abnormality, or critical illness at birth, said senior author Dr. Shu Qin Wei of the University of Montreal, Canada.",Vitamin D supplementation with doses of 2000 IU/d or lower during pregnancy may reduce the risk of fetal or neonatal mortality.,"At higher doses, any differences between women who took vitamin D and those who didn't were too small to rule out the possibility that they were due to chance. Taking vitamin D during pregnancy was safe, with no extra fetal or neonatal mortality, congenital abnormality, or critical illness at birth, said senior author Dr. Shu Qin Wei of the University of Montreal, Canada. And supplementation reduced infants' risk of being small for gestational age and improved their calcium levels and growth in the first 12 months of life.",CONCLUSIONS AND RELEVANCE Vitamin D supplementation during pregnancy is associated with a reduced risk of SGA and improved infant growth without risk of fetal or neonatal mortality or congenital abnormality. Vitamin D supplementation with doses of 2000 IU/d or lower during pregnancy may reduce the risk of fetal or neonatal mortality. Low vitamin D level status during pregnancy may expose the offspring to a suboptimal nutritional environment during critical phases of fetal development and may have long-term effects on offspring health outcomes.,"[2.0, 2.0, 2.0, 5.0, 4.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=34180824606&p=1pl&v=1&x=LymT53igqmp5seujNS7GFA
10.1001/jama.2013.277165,Medicine_8,"Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used.","Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used (Table 2 ; and eTable 4 in the Supplement), and without interaction across patient subsets, including demographics, previous treatment, risk scores, biomarkers or management (eFigure 3B and eFigure 4 in the Supplement).","Patients in the otamixaban group had about double the rate of the primary safety outcome of Thrombosis in Myocardial Infarction major or minor bleeding at day 7 compared with patients in the combination of UFH-plus-eptifibatide group (3.1 percent vs. 1.5 percent). Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used. Study anticoagulant was discontinued because of bleeding in 242 patients (4.7 percent) in the otamixaban group and in 95 patients (1.7 percent) in the UFH-plus-eptifibatide group.","Patients in the otamixaban group had an increased rate of the primary safety outcome of TIMI major or minor bleeding at day 7 compared with patients in the combination of UFHplus-eptifibatide group (3.1% vs 1.5%; RR, 2.13 [95% CI, 1.63-2.78]; P < .001; Table 2 ). Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used (Table 2 ; and eTable 4 in the Supplement), and without interaction across patient subsets, including demographics, previous treatment, risk scores, biomarkers or management (eFigure 3B and eFigure 4 in the Supplement). Study anticoagulant was discontinued because of bleeding in 242 patients (4.7%) in the otamixaban group and in 95 patients (1.7%) in the UFH-pluseptifibatide group (P < .001).","[4.0, 4.0, 5.0, 5.0, 4.0]",Medicine,train,4.4,news,http://www.sciencedaily.com/releases/2013/09/130901153354.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1002/emmm.201302567,Medicine_80,"""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body.",SMN2 mis-splicing increased during late-stage disease.,"""Our efforts to model the adult form of SMA were successful,"" says Kentaro Sahashi, M.D., Ph.D., a postdoctoral researcher and neurologist who is first author of the team's new paper. ""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body. We noted, importantly, marked liver and heart pathologies that were related to SMA's progression in adults.""","Systemic ASO injection elicited marked liver and heart pathologies, and resulted in decreased levels of circulating IGF1. SMN2 mis-splicing increased during late-stage disease. Our study also suggests that high SMN levels are not as critical in adults, and there is a broad therapeutic time window for treatment of adult-onset SMA.","[5.0, 5.0, 2.0, 4.0]",Medicine,train,4.0,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41598-018-29793-w,Medicine_82,"Well, as a turns out, your nose has a microbiome, too a and it might play a key role in how well you fight off colds.",The nasal microbiota clusters of subjects before the infection associated with the severity of clinical cold symptoms during rhinovirus infection.,"Well, as a turns out, your nose has a microbiome, too a and it might play a key role in how well you fight off colds. As if that werenat weird enough, researchers further found that study participantsa noses fell into six different nasal microbiome subtypes. These nasal microbiome types are linked to how bad your cold symptoms get, and how well you fight the virus off in the first place.","The clusters predominant of Staphylococcus, Corynebacterium/Alloiococcus, Moraxella, and Pseudomonadaceae/Mixed had characteristic inflammatory marker and viral load profiles in nasal washes. The nasal microbiota clusters of subjects before the infection associated with the severity of clinical cold symptoms during rhinovirus infection. Rhinovirus infection and probiotic intervention did not significantly alter the composition of nasal or fecal microbiota.","[1.0, 4.0, 5.0, 3.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=37227743738&p=1pl&v=1&x=2zyW9bON3VHP6zbXr8qTXQ
10.1098/rsos.171474,Medicine_83,"""We found a whole lot of nothing,"" Przybylski said.","Despite the null findings identified in the present study, history gives us reason to suspect the idea that violent video games drives aggressive behaviour will remain an unsettled question for parents, pundits and policy-makers.","""We found a whole lot of nothing,"" Przybylski said. ""Basically, we found that having information about the kinds of video games people played, how violent they were, how much time they spent on them, there was no linear connection."" ""We found pretty conclusive evidence that, among at least British teens, there is no connection between violent video game play and violent aggression,"" he said.","Until such findings are confirmed, however, we strongly would caution about drawing impulsive, thoughtless or potentially stigmatizing conclusions about members of such groups . Despite the null findings identified in the present study, history gives us reason to suspect the idea that violent video games drives aggressive behaviour will remain an unsettled question for parents, pundits and policy-makers. Although our results do have implications for these stakeholders, the present work holds special significance for those studying technology effects, in general, and video games, in particular.","[2.0, 5.0, 1.0, 2.0, 4.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=39875701073&p=1pl&v=1&x=dQGeE7OWTZ_rTEJvCuEV5g
10.1016/j.stemcr.2018.03.019,Medicine_84,X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.,We conclude that global DNA hypomethylation correlates with the presence of two active X chromosomes during reprogramming to iPSCs.,"Note: material may have been edited for length and content. For further information, please contact the cited source. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.","Thus, iPSCs display the same strong relationship between the presence of two active X chromosomes and global hypomethylation as female mouse ESCs . We conclude that global DNA hypomethylation correlates with the presence of two active X chromosomes during reprogramming to iPSCs. In Addition to the Non-repetitive Genome, Hypomethylation in Female iPSCs Affects the Repetitive Genome as well as ICRs One characteristic of the female XaXa ESC genome is hypomethylation of repetitive elements .","[4.0, 3.0, 4.0, 2.0]",Medicine,train,3.25,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.14814/phy2.13617,Medicine_85,"The study, published today in the journal Physiological Reports, is the first to assess the hormonal impact nighttime light exposure can have on young children.","Specifically, electronic device use before bedtime suppressed melatonin, delayed the timing of melatonin onset, increased sleep onset latency by 10-min, and negatively affected next day alertness.","The study, published today in the journal Physiological Reports, is the first to assess the hormonal impact nighttime light exposure can have on young children. The study comes at a time when use of electronics is rapidly expanding among this age group and adds to a growing body of evidence suggesting that-because of structural differences in their eyes-children may be more vulnerable to the impact light has on sleep and the body clock. ""In this study we found that these kids were extremely sensitive to light.""","Thus, the 1-h before bedtime may represent a window during which the circadian system is sensitive to perturbations (i.e., suppression of melatonin and phase delays) . Specifically, electronic device use before bedtime suppressed melatonin, delayed the timing of melatonin onset, increased sleep onset latency by 10-min, and negatively affected next day alertness. Considering that the screens of most electronic devices peak in the short wavelengths and lens transparency differences across age are most prominent at shorter wavelengths , we expect that young children are more sensitive to the effects of light emitted from these sources.","[4.0, 3.0, 3.0, 1.0]",Medicine,train,2.75,news,http://healthmedicinet.com/news/preschoolers-exposed-to-nighttime-light-lack-melatonin/
10.1016/j.cell.2018.04.034,Medicine_86,The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant.,"Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy.","""Because prostate cancer is so common, 7 percent is a significant number. The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant. This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy,"" says senior study author Arul Chinnaiyan, M.D., Ph.D., director of the Michigan Center for Translational Pathology.","We show that CDK12 mutants are genetically, transcriptionally, and phenotypically distinct from HRD and MMRD tumors. Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy. We detected aberrations of CDK12 in 25/360 of mCRPC patients (6.9%), 95% confidence interval (CI) [4.6%, 10 .2%] ( Figure 1A ).","[4.0, 4.0, 2.0, 4.0, 1.0]",Medicine,train,4.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1177/0956797617692041,Medicine_87,But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves.,Experiment 3a suggests that requiring participants to get their own refills alleviates the perverse effect of the free-refill response to a portion cap.,"This may have happened, the researchers surmise, because consumers wanted to get their ""money's worth"" - that is, they consumed more of the refill since they had already paid for it. But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves. ""Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption,"" the researchers write.","However, at least in this instance, it did not achieve the intended purpose of reducing consumption. Experiment 3a suggests that requiring participants to get their own refills alleviates the perverse effect of the free-refill response to a portion cap. Of 285 participants, 48.4% were male and 50.5% were female; 1.1% did not report their gender.","[4.0, 2.0, 4.0, 4.0]",Medicine,train,3.5,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1210/jc.2013-2350,Medicine_88,"In the CPG, The Endocrine Society recommends that a diagnosis be made if adult women have two of the three cardinal features of PCOS (diagnostic criteria supported by the NIH panel):* Excess production of male hormones called androgens.","Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease.","""The Society's recommendations allow physicians to make the diagnosis if clear symptoms are present without resorting to universal hormone tests or ultrasound screening."" In the CPG, The Endocrine Society recommends that a diagnosis be made if adult women have two of the three cardinal features of PCOS (diagnostic criteria supported by the NIH panel):* Excess production of male hormones called androgens. Other recommendations from the CPG include:

* Because women with PCOS face an increased risk of pregnancy complications such as gestational diabetes, preterm delivery and preeclampsia that can be exacerbated by obesity, women should have their body mass index, blood pressure and oral glucose tolerance assessed prior to conceiving;

* Following diagnosis, women with PCOS should be examined for skin and hair complications including excess hair growth and acne;

* Although women with PCOS have some of the same risk factors associated with the development of endometrial cancer, they should not routinely undergo ultrasound screening for endometrial thickness;

* To gauge metabolic risk, adolescents and adult women with PCOS should be screened for increased obesity using body mass index and waist circumference measurements;

* Clinicians should give adolescents and adult women with PCOS an oral glucose tolerance test to check for type 2 diabetes or impaired glucose tolerance because they are at increased risk of these conditions; and

* Initial treatment of type 2 diabetes or impaired glucose tolerance in women with PCOS should be diet and exercise, with metformin as a second-line therapy.","We suggest using the Rotterdam criteria for diagnosing PCOS (presence of two of the following criteria: androgen excess, ovulatory dysfunction, or polycystic ovaries). Evaluation of women with PCOS should exclude alternate androgen-excess disorders and risk factors for endometrial cancer, mood disorders, obstructive sleep apnea, diabetes, and cardiovascular disease. Thiazolidinediones have an unfavorable riskbenefit ratio overall, and statins require further study.","[1.0, 2.0, 3.0, 2.0, 1.0]",Medicine,train,1.8,news,http://www.newswise.com/articles/experts-clarify-conflicting-criteria-for-diagnosing-polycystic-ovary-syndrome
10.1073/pnas.1504869112,Medicine_89,"Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more.","While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change.","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests. While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change. Aboveground tree carbon stocks in these 16 plots averaged 75.1 Mg C ha -1 , which was representative for other ∼60 year old forests in the neotropics .","[2.0, 3.0, 3.0, 2.0, 4.0]",Medicine,train,2.8,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1038/s41467-018-08278-4,Medicine_9,"The results of the study showed that the regeneration process was most advanced when BMP2 was applied first, with BMP9 added a week after - in this case it led to the growth of more complete joint structures, even with some connections to the bone.",Control studies in which BMP2 treatment was followed by a second treatment with another BMP2 bead stimulated excessive bone growth but not the regeneration of joint structures ( Fig.,"""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper. The results of the study showed that the regeneration process was most advanced when BMP2 was applied first, with BMP9 added a week after - in this case it led to the growth of more complete joint structures, even with some connections to the bone. Humans are similar to mice in terms of the way our skeletons fit together, so this is possibly something that could be transferred over.","In both series, histological analyses indicated the regeneration of a complete joint structure that included a layer of articular cartilage lining the stump (Fig. Control studies in which BMP2 treatment was followed by a second treatment with another BMP2 bead stimulated excessive bone growth but not the regeneration of joint structures ( Fig. d; 0/16 digits) .","[3.0, 3.0, 3.0, 3.0, 3.0]",Medicine,train,3.0,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1073/pnas.1719801115,Medicine_90,"The researchers suggest that the active form of MinE briefly remains in the open conformation and can therefore ""jump on"" the nearest membrane-bound MinD.","Upon detachment from the membrane, MinE quickly reassumes its latent conformation with its MinD-and membrane-interaction regions buried (Fig.","Once in this state, MinE activates MinD's ATPase function, and both MinE and MinD-ADP are released from the membrane. The researchers suggest that the active form of MinE briefly remains in the open conformation and can therefore ""jump on"" the nearest membrane-bound MinD. ""This ability to switch between the two conformations is essential for the robustness of pattern formation, and allows pattern formation even for strongly enhanced MinE concentrations, as our simulations have shown,"" says Frey.","In addition, after dissociation of the MinDE complex and the release of MinD-ADP into the cytosol, MinE's MTS enables it to remain bound to the membrane, and the protein may reassociate repeatedly with other membrane-bound MinD molecules or (eventually) return to the cytosol . Upon detachment from the membrane, MinE quickly reassumes its latent conformation with its MinD-and membrane-interaction regions buried (Fig. In contrast, in silico and in vitro approaches both allow highly comparable conditions and the precise variation of parameters.","[4.0, 3.0, 3.0, 4.0, 2.0]",Medicine,train,3.2,news,http://ct.moreover.com/?a=33823920795&p=1pl&v=1&x=YBjBpHcja7cILepug4S5RQ
10.1001/jama.2018.20578,Medicine_94,"They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding.",The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude.,"They found that while it was associated with a lower risk of heart attacks and other cardiovascular events, it did lead to an increased risk of major bleeding. The results showed that:

Aspirin use was associated with an 11% lower risk of cardiovascular events. Approximately 250 patients needed to be treated with aspirin for 5 years to prevent a single heart attack, stroke or cardiovascular death.","6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64% (5% CI, 0.35%-0.7%) for major bleeding. The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude. Aspirin use was not associated with a reduction in cardiovascular mortality, and deaths due to bleeding were rare.","[5.0, 4.0, 1.0, 5.0]",Medicine,train,4.0,news,https://www.sciencedaily.com/releases/2019/01/190122114950.htm
10.1186/s40168-015-0071-z,Medicine_95,The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy.,"In aggregate, the bifidobacterial species distribution did not differ greatly between secretor-fed infants and non-secretor-fed infants.","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","However, it may be that only some bifidobacterial species would possess this advantage, due to differences in abilities of various species to consume fucosylated substrates. In aggregate, the bifidobacterial species distribution did not differ greatly between secretor-fed infants and non-secretor-fed infants. As the species of bifidobacteria present within an infant are dependent on environmental exposure, we tentatively conclude that this subset of geographically co-located infants was exposed to similar sets of bifidobacterial species.","[5.0, 2.0, 3.0, 4.0]",Medicine,train,3.5,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1038/s41598-017-18618-x,Medicine_96,"In addition, plasma triglycerides and total cholesterol levels were decreased and HDL (good lipids) was increased in the ACV group.",ACV decreased the serum lipid profile in mice fed a high cholesterol diet over days.,"This study administered 30 cc of ACV per day and found that it created significantly reduced body weight, BMI, hip-circumference, visceral adiposity index, and appetite score. In addition, plasma triglycerides and total cholesterol levels were decreased and HDL (good lipids) was increased in the ACV group. Weight checks are done at six and twelve-week intervals showed a significant reduction in BMI and body fat in this ACV group (Khezri et al, 2018).","Another means of action could involve the acetic acid component of ACV which is able to reduce the cell hydrogen potential hence could potentially facilitate diffusion across the plasma membrane of microbes. ACV decreased the serum lipid profile in mice fed a high cholesterol diet over days. Intragastric ACV addition induced a protective effect against erythrocyte, kidney and liver oxidative injury as well as lowering cholesterol levels .","[4.0, 1.0, 3.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=39098464353&p=1pl&v=1&x=1oF0R8OHMp2RCFFanDJNtw
10.1016/j.cell.2018.04.034,Medicine_97,"""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease.",The majority of CDK12 mutations (83%) were truncating and resulted in the loss of the kinase domain.,"That jumped to 7 percent for metastatic cancer, which indicates a more-aggressive form of the disease. ""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease. This could be a harbinger in early cancer,"" Chinnaiyan says.","CRPC genomes are more highly mutated than those of localized tumors; however, the magnitude of the increased mutation rate is not sufficient to explain the increased frequency of biallelic loss of CDK12. The majority of CDK12 mutations (83%) were truncating and resulted in the loss of the kinase domain. Missense mutations were clustered around conserved residues in the kinase domain ( Figure S1 ).","[2.0, 3.0, 1.0]",Medicine,train,2.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1007/s13524-014-0321-x,Medicine_99,"""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim.",Our study has limitations.,"In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status. ""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased.","Future research could consider whether this has changed the well-being implications of having children. Our study has limitations. First, although our fixed-effects approach is robust to attrition that varies only across individuals but not within, time-varying attrition risk that is correlated with childbearing could influence our results.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1001/jama.2018.20578,Medicine_tweet_0,"This meta-analysis confirms that use of #aspirin for primary prevention of #cardiovasculardisease is associated with a lower risk of CV events including CV mortality and nonfatal AMI and #stroke, and an increased risk of major bleeding.  ",Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared with no aspirin (57.1 per 10 000 participant-years with aspirin and 61.4 per 10 000 participant-years with no aspirin) (hazard ratio CONCLUSIONS AND RELEVANCE The use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.,"This meta-analysis confirms that use of #aspirin for primary prevention of #cardiovasculardisease is associated with a lower risk of CV events including CV mortality and nonfatal AMI and #stroke, and an increased risk of major bleeding.  ","The median age of trial participants was 62 years (range, 53-74), 77 501 (47%) were men, 30 361 (19%) had diabetes, and the median baseline risk of the primary cardiovascular outcome was 9.2% (range, 2.6%-15.9%). Aspirin use was associated with significant reductions in the composite cardiovascular outcome compared with no aspirin (57.1 per 10 000 participant-years with aspirin and 61.4 per 10 000 participant-years with no aspirin) (hazard ratio CONCLUSIONS AND RELEVANCE The use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,tweets,1087877579288297472
10.1001/jamaophthalmol.2017.4816,Medicine_tweet_1,"Trainees in clinic associated w longer appointment times, even for patients not seen by a trainee. ","The presence of a trainee in a clinic session was associated with longer mean appointment times, even in appointments in which the trainee was not present.","Trainees in clinic associated w longer appointment times, even for patients not seen by a trainee. ","Findings In this single-center cohort study of 49 448 outpatient ophthalmology appointments by 33 attending physicians, appointments with residents and fellows were 32% and 30% longer, respectively, than appointments without trainees. The presence of a trainee in a clinic session was associated with longer mean appointment times, even in appointments in which the trainee was not present. Meaning Academic medical centers face potential challenges in maintaining clinical efficiency and medical education, particularly in emerging value-based reimbursement models.","[5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,tweets,928668516101902337
10.1001/jamaneurol.2017.4618,Medicine_tweet_10,Acute lesions on diffusion #MRI of the brain could predict delayed neurological sequelae following acute CO poisoning. ,"Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001).",Acute lesions on diffusion #MRI of the brain could predict delayed neurological sequelae following acute CO poisoning. ,"Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001). The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2% (95% CI, 66.8%-83.7%) and 90.2% (95% CI, 86.8%-93.7%), respectively. In addition, the positive and negative predictive values were 73.1% (95% CI, 64.6%-81.6%) and 91.2% (95% CI, 87.9%-94.5%), respectively.","[2.0, 4.0, 3.0, 5.0, 4.0]",Medicine,train,3.6,tweets,958021925342760960
10.1111/infa.12017,Medicine_tweet_100,Ha- I guess once we start talking we forget to consider how other people feel: Infants Match Emotional Expressions ,The present findings are the first to show 5-month-olds match the faces and voices of other infants on the basis of global invariant properties common to facial and vocal emotional expressions.,Ha- I guess once we start talking we forget to consider how other people feel: Infants Match Emotional Expressions ,"These temporal and intensity patterns are invariant across face and voice and may specify different emotional valences which can be detected only in dynamic, moving expressions ) where changes in intensity and temporal patterns are evident. The present findings are the first to show 5-month-olds match the faces and voices of other infants on the basis of global invariant properties common to facial and vocal emotional expressions. Infants' intermodal matching of facial and vocal affective information in unfamiliar peers appears to emerge somewhat earlier (by 5 months but not 3.5 months of age) than their matching of facial and vocal affective information in unfamiliar adults (by 7 months but not 5 months of age; ) .","[4.0, 3.0, 1.0, 2.0, 4.0]",Medicine,train,2.8,tweets,350351449005371392
10.1016/j.cub.2013.11.012,Medicine_tweet_101,We show that generalization is different in subjects who never used a computer:  science news: ,"Interestingly, non-computer users still have a broad generalization as their generalization is significantly larger than zero even at the largest angular separation of 180 (30.0% 6 6.9%; p < 0.001, one-sample t test).",We show that generalization is different in subjects who never used a computer:  science news: ,"However, the computer users, compared to the non-computer-user group, generalize much more into other directions [interaction effect F(8, 96) = 6.9, p < 0.0001; main effect on groups F(2, 24) = 12.5, p < 0.0001, two-way ANOVA; Figure 2B ]. Interestingly, non-computer users still have a broad generalization as their generalization is significantly larger than zero even at the largest angular separation of 180 (30.0% 6 6.9%; p < 0.001, one-sample t test). There is no difference between the computer group and the student group, suggesting that subjects of different ages behave similarly as long as they are computer users.","[4.0, 4.0, 5.0, 1.0, 5.0]",Medicine,train,4.0,tweets,414133139586707456
10.1007/s00198-014-2732-3,Medicine_tweet_102,Calcium supplement intake and risk of cardiov... [Osteoporos Int. 2014] - PubMed - NCBI ,"At baseline, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared with those who did not take calcium supplements.",Calcium supplement intake and risk of cardiov... [Osteoporos Int. 2014] - PubMed - NCBI ,"Results During 24 years of follow-up, 4,565 cardiovascular events occurred (2,709 CHD and 1,856 strokes). At baseline, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared with those who did not take calcium supplements. After multivariable adjustment for age, body mass index, dietary calcium, vitamin D intake, and other CVD risk factors, the relative risk of CVD for women taking >1,000 mg/day of calcium supplements compared with none was 0.82 (95 % confidence interval [CI] 0.74 to 0.92; p for trend <0.001).","[3.0, 2.0, 3.0, 1.0, 3.0]",Medicine,train,2.4,tweets,468539681773068288
10.1111/all.13333,Medicine_tweet_104,"New paper: Influenza burden, prevention and treatment in asthma   @username @username @username @username","Asthma patients seemed to have a higher risk of being admitted to the intensive care unit (ICU) or to have a more severe disease course when hospitalized for influenza, Severe disease was especially common in those developing pneumonia, but did not seem to be related to the severity of underlying asthma.","New paper: Influenza burden, prevention and treatment in asthma   @username @username @username @username","Interestingly, influenza-related hospitalization costs in children with asthma may be lower than in children with other chronic conditions and were very close to costs in children without comorbidity. Asthma patients seemed to have a higher risk of being admitted to the intensive care unit (ICU) or to have a more severe disease course when hospitalized for influenza, Severe disease was especially common in those developing pneumonia, but did not seem to be related to the severity of underlying asthma. In a multivariate analysis of H1N1 pediatric patients, asthma was associated with increased mortality in ICU-admitted children and adolescents (OR 1.34, P = .05).","[2.0, 2.0, 4.0, 4.0, 3.0]",Medicine,train,3.0,tweets,928044868596850689
10.1093/gerona/glt162,Medicine_tweet_105,RT @username New study: Chronological age is not a relevant marker for healthy #aging. ,Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in health trajectories across the life span.,RT @username New study: Chronological age is not a relevant marker for healthy #aging. ,"Instead, different people appear to be experiencing widely different health trajectories with widely different health outcomes at the same ages. Our findings suggest that the time has arrived to reconsider the importance of chronological age and to design better social policies to reflect the substantial variation in health trajectories across the life span. These findings have important implications for five policy issues surrounding aging.","[3.0, 5.0, 5.0, 4.0, 4.0]",Medicine,train,4.2,tweets,403280517866348544
10.1016/j.scitotenv.2019.04.266,Medicine_tweet_107,"Conservation, bushmeat markets and health risks:  Pruvot et al assessed health risks by conducting questionnaires with wildlife consumers in Laos and showed that consumption of bushmeat in urban areas was mostly driven by dietary preference and tradition
 ","Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited unintended consequences on more vulnerable communities.","Conservation, bushmeat markets and health risks:  Pruvot et al assessed health risks by conducting questionnaires with wildlife consumers in Laos and showed that consumption of bushmeat in urban areas was mostly driven by dietary preference and tradition
 ","This suggests that the cost of law enforcement can be internalized by wildlife vendors as part of their business operations, while this cost may not be tolerable at the individual level for a wildlife consumer. Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited unintended consequences on more vulnerable communities. Doing so, we demonstrated high rates of direct contact between bushmeat and people visiting the market, highlighting that this may be an under-estimated route of disease transmission in the bushmeat system.","[4.0, 5.0, 1.0, 3.0]",Medicine,train,3.0,tweets,1129283088607920129
10.1186/s10194-018-0916-5,Medicine_tweet_108,"""Insomnia and migraine as closely related"" as per researchers from South Korea representing various colleges – ",Migraineurs with insomnia experienced a higher headache intensity and impact of headache (HIT-6 score) compared to migraineurs without insomnia (Table 3) .,"""Insomnia and migraine as closely related"" as per researchers from South Korea representing various colleges – ","In contrast, insomnia has a significant impact on the clinical presentation of migraine. Migraineurs with insomnia experienced a higher headache intensity and impact of headache (HIT-6 score) compared to migraineurs without insomnia (Table 3) . It is possible that their distinct anatomy and pathophysiology contribute to the contrast findings.","[5.0, 3.0, 4.0, 4.0, 2.0]",Medicine,train,3.6,tweets,1062586173812396032
10.1186/s12916-017-0986-2,Medicine_tweet_109,Old Age Alone Not to Blame for Surgical Complications. Study @username  by @username Dr. Watt:  #geriatrics @username,"One study found that, while frail patients with postoperative complications had prolonged hospitalizations (P < 0.001), those without postoperative complications did not (P = 0.19) .",Old Age Alone Not to Blame for Surgical Complications. Study @username  by @username Dr. Watt:  #geriatrics @username,"Among six studies that investigated frailty as a prognostic factor for prolonged hospitalization, there was a significant association identified in four studies . One study found that, while frail patients with postoperative complications had prolonged hospitalizations (P < 0.001), those without postoperative complications did not (P = 0.19) . Age was identified as a significant prognostic factor for prolonged hospitalization in only two of six studies 2 .","[2.0, 2.0, 4.0, 3.0]",Medicine,train,2.75,tweets,951832472873967616
10.1073/pnas.1509654112,Medicine_tweet_11,Male and female brains are more similar than previously thought. Interesting paper in PNAS ,"Here we show that, although there are sex/gender differences in brain and behavior, humans and human brains are comprised of unique ""mosaics"" of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males.",Male and female brains are more similar than previously thought. Interesting paper in PNAS ,"Such an alignment may be predicted by the classic view of sexual differentiation of the brain, according to which masculinization and defeminization of the brain are under the sole influence of testosterone (9). Here we show that, although there are sex/gender differences in brain and behavior, humans and human brains are comprised of unique ""mosaics"" of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males. Our results demonstrate that regardless of the cause of observed sex/gender differences in brain and behavior (nature or nurture), human brains cannot be categorized into two distinct classes: male brain/female brain.","[5.0, 1.0, 4.0, 3.0]",Medicine,train,5.0,tweets,671443107045621761
10.1038/nature12775,Medicine_tweet_110,#sr Stepwise-binding process w/ decreasing affinity:Structural basis for Ca2+ selectivity of voltage-gated Ca channel ,This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca 21 ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwisebinding process.,#sr Stepwise-binding process w/ decreasing affinity:Structural basis for Ca2+ selectivity of voltage-gated Ca channel ,Our results reveal interactions of hydrated Ca 21 with two high-affinity Ca 21 -binding sites followed by a third lower-affinity site that would coordinate Ca 21 as it moves inward. This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca 21 ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwisebinding process. The multi-ion selectivity filter of our Ca V Ab model establishes a structural framework for understanding the mechanisms of ion selectivity and conductance by vertebrate Ca V channels.,"[4.0, 3.0, 3.0, 4.0]",Medicine,train,3.5,tweets,406122131508846592
10.1001/jamapediatrics.2013.4951,Medicine_tweet_111,"Feed &amp; satiety response in INFANTS linked to obesity in childhood, this is where prevention begins @username .","Similar patterns are to be expected in the wider population; therefore, this study corroborates the hypothesis that a hearty appetite in infancy is a risk factor for faster weight gain.","Feed &amp; satiety response in INFANTS linked to obesity in childhood, this is where prevention begins @username .","25 Our findings indicate that within the same family the sibling with the higher appetite grows faster than the sibling with the lower appetite. Similar patterns are to be expected in the wider population; therefore, this study corroborates the hypothesis that a hearty appetite in infancy is a risk factor for faster weight gain. Our study has several strengths.","[4.0, 4.0, 4.0, 3.0]",Medicine,train,3.75,tweets,435541800690794497
10.1001/jama.2013.277165,Medicine_tweet_113,The TAO RCT—#anticoagulation with #otamixaban in #ACS ,"At that time, the rates of the primary efficacy outcome in the higher-dose otamixaban group was 4.7% (the one selected to go forward) and was 5.6% in the UFH-pluseptifibatide group (adjusted RR, 0.848; 95% CI, 0.662-1.087) but the lower-dose group fulfilled the prespecified criteria for futility with a RR of more than 1 (primary efficacy outcome, 6.3%; RR, 1.130; 95% CI, 0.906-1.408) and was discontinued.",The TAO RCT—#anticoagulation with #otamixaban in #ACS ,"The design of the TAO trial has been published. At that time, the rates of the primary efficacy outcome in the higher-dose otamixaban group was 4.7% (the one selected to go forward) and was 5.6% in the UFH-pluseptifibatide group (adjusted RR, 0.848; 95% CI, 0.662-1.087) but the lower-dose group fulfilled the prespecified criteria for futility with a RR of more than 1 (primary efficacy outcome, 6.3%; RR, 1.130; 95% CI, 0.906-1.408) and was discontinued. Events occurring among patients who received the discontinued otamixaban dose were not considered in primary outcome analyses, which pertained only to participants randomized to the higher dose of otamixaban vs UFH plus eptifibatide, not to the low-dose otamixaban group.","[3.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.6,tweets,380062458775220225
10.1016/j.ejca.2017.11.022,Medicine_tweet_115,"Red meat is not associated with breast cancer in the UK - HR 0.99. Very small association for processed meat. 
Headlines witter on about bacon, but it's not mentioned in the paper.
","Of the eleven cohort studies, ten reported the association between red meat consumption and overall risk of breast cancer; of these, six also reported results separately for pre-menopausal and post-menopausal breast cancer.","Red meat is not associated with breast cancer in the UK - HR 0.99. Very small association for processed meat. 
Headlines witter on about bacon, but it's not mentioned in the paper.
","A further five studies were excluded due to repeat analyses conducted on the same cohort and two due to inadequate exposure information; resulting in ten eligible cohort studies in addition to UK Biobank ( Figure 1) . Of the eleven cohort studies, ten reported the association between red meat consumption and overall risk of breast cancer; of these, six also reported results separately for pre-menopausal and post-menopausal breast cancer. The ten studies produced a pooled relative risk for breast cancer, overall, of 1.03 (95% CI 0.99-1.08) (Figure 2 ).","[2.0, 3.0, 1.0, 1.0]",Medicine,train,1.75,tweets,948652066527825920
10.1098/rsbl.2014.0993,Medicine_tweet_116,"Ephedra foeminea production of drops on fullmoons to attract insects for pollination:

This raises possibility that",The moon may further be crucial for pollinator attraction.,"Ephedra foeminea production of drops on fullmoons to attract insects for pollination:

This raises possibility that","This fits well with our field sites in the Balkans, where a cloudy sky is rare in the summer and no high trees shade the environment. The moon may further be crucial for pollinator attraction. While investigated species of Gnetum emit easily detectable scent (C. Rydin 2014, personal observation and ), Ephedra does not.","[3.0, 2.0, 5.0, 1.0, 3.0]",Medicine,train,3.0,tweets,583797469449945088
10.1001/jama.2018.20578,Medicine_tweet_117,"Meta-analysis evaluating aspirin for primary prevention in cardiovascular disease – the double-edged sword: NNT 265  (to prevent CV mortality/nonfatal MI + stroke); NNH 210 (major bleeding). #JAMA #CVD
 ",The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude.,"Meta-analysis evaluating aspirin for primary prevention in cardiovascular disease – the double-edged sword: NNT 265  (to prevent CV mortality/nonfatal MI + stroke); NNH 210 (major bleeding). #JAMA #CVD
 ","6 This study showed that when analysis was restricted to populations with observation-derived 10-year cardiovascular event rate estimates of 10% or more, aspirin use was associated with an absolute risk decrease of 0.51% (5% CI, 0.06%-0.3%) for the cardiovascular composite outcome, but an absolute risk increase of 0.64% (5% CI, 0.35%-0.7%) for major bleeding. The current study demonstrates that the absolute risk reduction for cardiovascular events and absolute risk increase for major bleeding associated with aspirin use were of similar magnitude. Aspirin use was not associated with a reduction in cardiovascular mortality, and deaths due to bleeding were rare.","[3.0, 5.0, 2.0, 4.0]",Medicine,train,3.5,tweets,1087869932593926144
10.1001/jama.2013.277165,Medicine_tweet_118,#Anticoagulation With #Otamixaban and Ischemic Events in NSTE-ACS ,"Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used (Table 2 ; and eTable 4 in the Supplement), and without interaction across patient subsets, including demographics, previous treatment, risk scores, biomarkers or management (eFigure 3B and eFigure 4 in the Supplement).",#Anticoagulation With #Otamixaban and Ischemic Events in NSTE-ACS ,"Patients in the otamixaban group had an increased rate of the primary safety outcome of TIMI major or minor bleeding at day 7 compared with patients in the combination of UFHplus-eptifibatide group (3.1% vs 1.5%; RR, 2.13 [95% CI, 1.63-2.78]; P < .001; Table 2 ). Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used (Table 2 ; and eTable 4 in the Supplement), and without interaction across patient subsets, including demographics, previous treatment, risk scores, biomarkers or management (eFigure 3B and eFigure 4 in the Supplement). Study anticoagulant was discontinued because of bleeding in 242 patients (4.7%) in the otamixaban group and in 95 patients (1.7%) in the UFH-pluseptifibatide group (P < .001).","[4.0, 2.0, 2.0, 1.0, 2.0]",Medicine,train,2.2,tweets,374109851703869440
10.1038/s41467-018-07557-4,Medicine_tweet_12,"""We show that nearly four million people and 70% of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost."" .. ""where thaw-related ground instability can cause severe damage""

 ","Here, the ground temperature and thaw of near-surface permafrost was considered to be the most important factor affecting infrastructure hazard followed by GIC, relative increase of ALT, fine-grained sediment content and slope gradient.","""We show that nearly four million people and 70% of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost."" .. ""where thaw-related ground instability can cause severe damage""

 ","The AHP developed is a multi-objective, multicriteria decision-making approach to analyse complicated problems such as the determination of relative roles of factors affecting geohazards 70 . Here, the ground temperature and thaw of near-surface permafrost was considered to be the most important factor affecting infrastructure hazard followed by GIC, relative increase of ALT, fine-grained sediment content and slope gradient. 2).","[3.0, 4.0, 3.0, 2.0]",Medicine,train,3.0,tweets,1073349529884336133
10.1001/jama.2018.20578,Medicine_tweet_120,"In @username  

Bottom line of this latest analysis calculates out as follows: For every 265 folks taking #aspirin for median 5 years, 1 #heartattack, #stroke or death is likely prevented &amp; for every 210 folks on aspirin, 1 serious bleeding event occurs","In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding.","In @username  

Bottom line of this latest analysis calculates out as follows: For every 265 folks taking #aspirin for median 5 years, 1 #heartattack, #stroke or death is likely prevented &amp; for every 210 folks on aspirin, 1 serious bleeding event occurs","19, 22 Increasing adoption of additional primary prevention strategies, such as risk factor modification and development of public health initiatives, may limit the applicability of earlier studies to current practice. In this meta-analysis, the use of aspirin in individuals without cardiovascular disease was associated with a lower risk of cardiovascular events and an increased risk of major bleeding. This information may inform discussions with patients about aspirin for primary prevention of cardiovascular events and bleeding.","[4.0, 2.0, 4.0, 4.0, 4.0]",Medicine,train,3.6,tweets,1087751911909089280
10.1002/ijc.28956,Medicine_tweet_121,Positive effect of primary prevention measures for melanoma? ,As seen across all ages those diagnosed with lesions >1 mm were at higher risk of death of those with thin melanoma.,Positive effect of primary prevention measures for melanoma? ,"With regard to survival, Queensland melanoma patients in this young age group had virtually the same survival rate at around 96% as all Australians aged 0-19, 20- and 0-9 years from 199 to 200 and young adults aged 20-2 years in the USA, and better survival at 5 years than seen in Australians aged 60-69 (91%). As seen across all ages those diagnosed with lesions >1 mm were at higher risk of death of those with thin melanoma. The generally favourable outcome in Queensland is likely due in part to early detection resulting from increased skin cancer awareness.","[2.0, 2.0, 3.0, 4.0, 2.0]",Medicine,train,2.6,tweets,464970007298846720
10.1186/s10194-018-0955-y,Medicine_tweet_122,@username guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention just published on #TheJournalofHeadacheandPain and available at  ,"Results: We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine.",@username guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention just published on #TheJournalofHeadacheandPain and available at  ,"Results: We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine. For several clinical questions, there was not enough evidence to provide recommendations using the GRADE approach and recommendations relied on experts' opinion. Conclusion: Monoclonal antibodies acting on the calcitonin gene-related peptide are new drugs which can be recommended for migraine prevention.","[3.0, 2.0, 4.0, 1.0]",Medicine,train,2.5,tweets,1085833674418020352
10.1016/j.biopsych.2013.07.024,Medicine_tweet_123,New study ( prenatal exposure to glucucorticoids or smoking raise adult daughters' nicotine dependence but not sons',"Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid exposure (60), we also hypothesized that links between prenatal glucocorticoids and offspring ND would be stronger for daughters.",New study ( prenatal exposure to glucucorticoids or smoking raise adult daughters' nicotine dependence but not sons',"Thus, we propose that maternal cortisol levels might mediate the relation between MSDP and offspring ND. Given evidence for more pronounced MSDP-offspring smoking links in daughters (12-14, 16,17,19,24) and for sex differences in prenatal glucocorticoid levels (59) and offspring outcomes after prenatal glucocorticoid exposure (60), we also hypothesized that links between prenatal glucocorticoids and offspring ND would be stronger for daughters. showed associations between fetal testosterone exposure and alterations in responsiveness of neural reward regions and behavioral approach tendencies, both of which have been associated with ND .","[5.0, 4.0, 3.0, 3.0]",Medicine,train,3.75,tweets,423478257359392768
10.1073/pnas.1204651110,Medicine_tweet_124,Severe drought has lasting effects on Amazon -  Nature.comSevere drought has lasting effects... ,We found no in situ observations over the region affected by the 2005 drought that could be used to directly verify our results.,Severe drought has lasting effects on Amazon -  Nature.comSevere drought has lasting effects... ,"The delayed recovery of QSCAT in southwestern Amazonia suggests a decline in more long-lived aspects of canopy structure with recovery timescales greater than 3-4 y, such as loss of leaves or dieback of branches, or potential tree falls creating large gaps. We found no in situ observations over the region affected by the 2005 drought that could be used to directly verify our results. The effects of extreme droughts on the understory light environment of tropical forests may be compared with the effects of tree-fall gaps, although on much larger scales (27) .","[1.0, 2.0, 1.0]",Medicine,train,1.3333333333333333,tweets,283317092286083072
10.1098/rsbl.2014.0255,Medicine_tweet_125,"Galápagos hawk and feather lice showed patterns of co-divergence across temporal and spatial scales on the islands.
","Similarly, D. regalis showed an extraordinarily high degree of population genetic structure among geographical islands.","Galápagos hawk and feather lice showed patterns of co-divergence across temporal and spatial scales on the islands.
","Further analysis of the genetic clusters revealed a clear correspondence with the geographical islands on which populations were sampled. Similarly, D. regalis showed an extraordinarily high degree of population genetic structure among geographical islands. AMOVA and pairwise permutation tests showed that populations of lice on each island were highly differentiated (overall F ST ¼ 0.429, p , 0.0001).","[1.0, 3.0, 3.0]",Medicine,train,2.333333333333333,tweets,497496916322951168
10.1038/s41588-018-0175-z,Medicine_tweet_126,"Seeing an enhancer interact with a promoter to activate a gene in a living single cell, in real-time, for the 1st time (via  genome editing and color imaging)  @username by @username and colleagues @username ",We show that sustained proximity of the enhancer to its target is required for activation.,"Seeing an enhancer interact with a promoter to activate a gene in a living single cell, in real-time, for the 1st time (via  genome editing and color imaging)  @username by @username and colleagues @username ","Even for a compact genome such as Drosophila melanogaster, at least 30% of enhancer-promoter interactions occur over 20 kb, and in many cases over intervening genes . We show that sustained proximity of the enhancer to its target is required for activation. Transcription in turn affects the three-dimensional topology as it enhances the temporal stability of the proximal conformation and is associated with further spatial compaction.","[4.0, 1.0, 5.0, 3.0]",Medicine,train,3.0,tweets,1021412274429296640
10.1111/papt.12095,Medicine_tweet_127,"Broad minded affective coping (BMAC), a therapeutic technique, effective to elicit positive memories  ","It would also be useful to evaluate this technique within a clinical group, where problems around accessing positive social memories and emotions will be more pronounced.","Broad minded affective coping (BMAC), a therapeutic technique, effective to elicit positive memories  ","In future research, it would be helpful to have a comparison group who complete a relaxation imagery exercise to allow for the exploration of change brought about by the social BMAC above that of relaxation alone. It would also be useful to evaluate this technique within a clinical group, where problems around accessing positive social memories and emotions will be more pronounced. Nonetheless, the current study helps us to establish a proof-of-concept regarding the social BMAC.","[3.0, 4.0, 3.0, 2.0]",Medicine,train,3.0,tweets,723067166199713792
10.1016/j.jadohealth.2015.02.018,Medicine_tweet_128,RT @username: Academic study--Sexual assaults have reached epidemic levels among college women.  #fem2,"Before entering college, 28% of women had experienced attempted or completed rape.",RT @username: Academic study--Sexual assaults have reached epidemic levels among college women.  #fem2,"In addition, this study provides temporal resolution unavailable in most previous reports. Before entering college, 28% of women had experienced attempted or completed rape. During their first year, one of six female students had experienced A/C IR or A/C FR.","[1.0, 1.0, 3.0, 3.0, 4.0]",Medicine,train,3.0,tweets,600982012313370624
10.1063/1.4913758,Medicine_tweet_129,"@username @username If you want to argue that there is no social polarization in Venezuela, I don't know what to tell you. There are a whole lot of scholarly articles on this.

Even Venezuelan Twitter is polarized: ","In fact, during this day the percentage of users tweeting from Venezuela (≈ 20%) was very low in comparison to the rest of the days (average around > 80%).","@username @username If you want to argue that there is no social polarization in Venezuela, I don't know what to tell you. There are a whole lot of scholarly articles on this.

Even Venezuelan Twitter is polarized: ","Besides a large amount of users from all around the globe joined to the conversation, making the topic international, rather than local from Venezuela. In fact, during this day the percentage of users tweeting from Venezuela (≈ 20%) was very low in comparison to the rest of the days (average around > 80%). Hence, our set of Venezuelan elite were not capable of polarizing this majority of worldwide users.","[1.0, 3.0, 1.0, 2.0]",Medicine,train,1.75,tweets,1100622633580851200
10.1016/j.jpsychires.2013.06.014,Medicine_tweet_130,Prisoners in 10-week #yoga course experienced improved behavioural control &amp; decreased psychological distress: ,"Participation in the yoga course significantly influenced positive affect as measured by the PANAS, F(1,86) ¼ 5.26, p ¼ 0.024.",Prisoners in 10-week #yoga course experienced improved behavioural control &amp; decreased psychological distress: ,"The average time that participants in the yoga group spent practising yoga (outside of class) did not differ significantly when compared to the time spent by the control group doing other forms of exercise (167.1 AE 48.4 min vs. 241.76 AE 27.0 min, respectively), t(75) ¼ À1.46, p ¼ 0.15. Participation in the yoga course significantly influenced positive affect as measured by the PANAS, F(1,86) ¼ 5.26, p ¼ 0.024. Exploration of simple effects demonstrated that participants did not differ in positive affect at baseline, F(1,86) < 1, but at Time 2 the yoga group reported significantly higher positive affect than the control group, F(1,86) ¼ 6.33, p ¼ 0.014.","[4.0, 3.0, 4.0, 4.0]",Medicine,train,3.75,tweets,357523208028684288
10.1016/j.cell.2013.12.044,Medicine_tweet_131,Closer to bite free? RT @username: New Vosshall Lab CELL paper out today:  Mosquitoes that can't sense carbon dioxide,The role of mosquito vision in host-seeking and its interactions with odors warrants further investigation.,Closer to bite free? RT @username: New Vosshall Lab CELL paper out today:  Mosquitoes that can't sense carbon dioxide,"In addition, it is possible that diurnal patterns of flight periodicity in Ae. The role of mosquito vision in host-seeking and its interactions with odors warrants further investigation. Neither chemosensory input in isolation fully encodes the experience of the food or beverage, which may explain why humans with olfactory dysfunction report difficulties with enjoyment of food and wine .","[4.0, 2.0, 1.0, 2.0, 4.0]",Medicine,train,1.0,tweets,439155896846155777
10.1534/genetics.116.197285,Medicine_tweet_132,Paper on the Evolution of Resistance Against #CRISPR/Cas9 Gene Drive. ,"Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow.",Paper on the Evolution of Resistance Against #CRISPR/Cas9 Gene Drive. ,"We find that in most scenarios P SGV is higher than P μ . Thus, resistance is more likely to evolve from alleles in the SGV than from de novo mutation after introduction of the driver, unless the drive is very slow. The key parameter determining the likelihood of resistance from NHEJ is the product N e δ, similar to the role played by θ = 4N e μ for de novo mutation.","[3.0, 1.0, 1.0, 3.0]",Medicine,train,2.0,tweets,831607450742747137
10.1002/oby.20610,Medicine_tweet_133,"Home-school #kids thinner, leaner, and have better #diet than public school kids  #philosophy of #education #health","Traditional school status was associated with increased reported intake of trans fat (p=0.0136), total sugar (p=0.0342), added sugars (p=0.0164), calcium (p=0.0109), and decreased consumption of fiber (p=0.0408), and fruits and vegetables (p=0.0005).","Home-school #kids thinner, leaner, and have better #diet than public school kids  #philosophy of #education #health","No significant differences were detected between TSC and HSC with respect to the amount of time spent engaged in daily moderate to vigorous physical activity. Traditional school status was associated with increased reported intake of trans fat (p=0.0136), total sugar (p=0.0342), added sugars (p=0.0164), calcium (p=0.0109), and decreased consumption of fiber (p=0.0408), and fruits and vegetables (p=0.0005). Being traditionally schooled was also nearly significantly associated with increased energy intake (p=0.0584).","[3.0, 2.0, 4.0, 3.0, 4.0]",Medicine,train,3.2,tweets,391719121970544640
10.1016/j.amepre.2016.07.031,Medicine_tweet_134,Healthcare Provider Contact &amp; PrEP in Baltimore Men Who Have Sex w Men [a]  HT @username,"Results: There were 401 HIV-negative participants, of whom 168 (42%) were aware of PrEP.",Healthcare Provider Contact &amp; PrEP in Baltimore Men Who Have Sex w Men [a]  HT @username,"Results: There were 401 HIV-negative participants, of whom 168 (42%) were aware of PrEP. Visiting a healthcare provider in the past 12 months, receiving an HIV test from a provider, and having a sexually transmitted infection test in the past 12 months were not significantly associated with PrEP awareness. PrEP awareness was associated with being out to a healthcare provider (OR¼2.97, 95% CI¼1.78, 4.96, po0.001); being tested for HIV (OR¼1.50, 95% CI¼1.06, 2.13, p¼0.023); and receiving condoms from an HIV/AIDS CBO (OR¼2.59, 95% CI¼1.43, 4.64, p¼0.001).","[2.0, 2.0, 3.0, 4.0, 1.0]",Medicine,train,2.4,tweets,784184031676071936
10.1089/apc.2017.0171,Medicine_tweet_135,"Healthcare insurance barriers remain a major obstacle against proving #HIV prophylaxis to Black and Hispanic men who have sex with men.
","This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups.","Healthcare insurance barriers remain a major obstacle against proving #HIV prophylaxis to Black and Hispanic men who have sex with men.
","These regional disparities might reflect the more limited expansion of Medicaid in the south than in the rest of the country. This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups. Lower education frequently coincides with lower health literacy and reduced knowledge of preventive services such as PrEP.","[2.0, 2.0, 2.0, 3.0, 2.0]",Medicine,train,2.2,tweets,948737570141278208
10.1001/jamapediatrics.2018.3101,Medicine_tweet_136,Association of Prenatal Exposure to Air Pollution With Autism  and some media:  It's complicated: ,Meaning Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children.,Association of Prenatal Exposure to Air Pollution With Autism  and some media:  It's complicated: ,"Findings In this population-based cohort study of 132 256 births, maternal exposure to nitric oxide during pregnancy was associated with increased risk of autism spectrum disorder in offspring. Meaning Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children. The use of LUR models provides greater spatial resolution and the ability to capture small-scale, localized variation compared with reliance on air-quality monitoring data alone.","[4.0, 4.0, 4.0, 5.0, 4.0]",Medicine,train,4.2,tweets,1064597051869155328
10.1073/pnas.1613193114,Medicine_tweet_137,#climatechange expected to have negative impact on US electric grid  #climateandhealth #putkids1st #KidsEnvHealth,"As such, even absent population and income changes, climate change will demand significant changes to the electric grid.",#climatechange expected to have negative impact on US electric grid  #climateandhealth #putkids1st #KidsEnvHealth,"Overall, if the US had faced, over the past decade, the warmer climate that scientists predict for the future, our results show that much greater generation or storage capacity would have been needed. As such, even absent population and income changes, climate change will demand significant changes to the electric grid. ERCOT covers Texas only and can be thought of as more representative of warmer regions.","[2.0, 5.0, 2.0, 5.0]",Medicine,train,5.0,tweets,829353787303272448
10.1177/0956797614534694,Medicine_tweet_138,Fewer than 5 hrs of sleep had about 20% higher rate of reported a false memory &amp; other effects ,"Planned comparisons revealed that in the morning-encoding condition, the false memory rate was significantly higher in the sleep-deprived group than in the rested group, t(51) = 2.01, p = .04 (two-tailed), Cohen's d = 0.56.",Fewer than 5 hrs of sleep had about 20% higher rate of reported a false memory &amp; other effects ,"However, there was a significant interaction between the factors, F(1, 99) = 4.52, p = .04. Planned comparisons revealed that in the morning-encoding condition, the false memory rate was significantly higher in the sleep-deprived group than in the rested group, t(51) = 2.01, p = .04 (two-tailed), Cohen's d = 0.56. However, in the evening-encoding condition, there was no significant difference in the false memory rate between sleep-deprived and rested participants, t(52) = 0.98, p = .33 (Fig.","[4.0, 5.0, 4.0, 5.0, 3.0]",Medicine,train,4.2,tweets,489700861963427840
10.1038/s41598-018-26198-7,Medicine_tweet_139,"A new Harvard study found that when mice are randomized to either a stretching (10 minutes/day) vs. no stretching group, those in the stretching group had a 52% reduction in the growth of implanted breast cancer tumors growth... ","Both active and passive stretching had similar effects compared with anesthesia alone, and there was no significant difference between the effects of active and passive stretching 23 .","A new Harvard study found that when mice are randomized to either a stretching (10 minutes/day) vs. no stretching group, those in the stretching group had a 52% reduction in the growth of implanted breast cancer tumors growth... ","While our method of stretching does not fully suspend the animal, since its front feet are allowed to grip a bar of the cage, some stress inevitably results from being restrained by the tail, and muscle activity is required to maintain the stretched posture; in the no stretch group, we did not hold the mice by the tail, as they have a tendency to pull away which can cause inadvertent stretching of tissues. Both active and passive stretching had similar effects compared with anesthesia alone, and there was no significant difference between the effects of active and passive stretching 23 . This result demonstrated a mechanical effect of stretching that was not due to stress or muscle activity (since these were identical in the two anesthetized groups).","[4.0, 2.0, 1.0, 3.0]",Medicine,train,2.5,tweets,999281918742016000
10.1098/rsos.150710,Medicine_tweet_14,Our new paper using MTurk finds no evidence that artificial monitoring cues influence online donations to charity ,This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online charity donation on MTurk.,Our new paper using MTurk finds no evidence that artificial monitoring cues influence online donations to charity ,"By contrast, the control variables of culture, age, sex and previous charity giving frequency did predict donations. This work supports the importance of cultural differences and enduring individual differences in prosocial behaviour and shows that a range of artificial monitoring cues do not reliably boost online charity donation on MTurk. None of the monitoring primes we tested had a significant effect on charitable giving.","[3.0, 4.0, 5.0, 5.0, 5.0]",Medicine,train,4.4,tweets,788976892560805888
10.1126/scitranslmed.aah4066,Medicine_tweet_140,[Research Articles] Inflammasome inhibition prevents {alpha}-synuclein pathology and dopaminergic neurodegeneration in mice  ,"Inflammasome components are up-regulated, and activation occurs via NLRP3 in the 6-OHDA mouse model of PD.",[Research Articles] Inflammasome inhibition prevents {alpha}-synuclein pathology and dopaminergic neurodegeneration in mice  ,"Inflammasome components are up-regulated in patients with PD. Inflammasome components are up-regulated, and activation occurs via NLRP3 in the 6-OHDA mouse model of PD. NLRP3 and ASC are up-regulated in the MitoPark mouse model of PD.","[5.0, 1.0, 3.0, 3.0]",Medicine,train,3.0,tweets,1057698005728485376
10.1016/j.socscimed.2018.10.008,Medicine_tweet_141,Research by Dr Sarah Johns identifies that male infants and birth complications increase chances of postnatal depression   @username@username #BiologicalAnthropology #HealthMatters #depression #postnatal ,"We did not find much evidence for the additive effects of birth complications with other PND risk factors in our sample (low SES, low social support, and a history of depression, anxiety, and stress) as anticipated.",Research by Dr Sarah Johns identifies that male infants and birth complications increase chances of postnatal depression   @username@username #BiologicalAnthropology #HealthMatters #depression #postnatal ,"Irrespective of whether post-birth infections are experienced, birth complications are likely to be stressful for women, particularly if they resulted in emergency procedures being undertaken. We did not find much evidence for the additive effects of birth complications with other PND risk factors in our sample (low SES, low social support, and a history of depression, anxiety, and stress) as anticipated. Only one predicted interaction effect was found; male infants increased PND risk when associated with complicated births when PND was measured by clinical diagnosis, but not when PND was determined retrospectively, and inclusion of the interaction term only marginally improved the model performance.","[1.0, 1.0, 3.0, 1.0]",Medicine,train,1.5,tweets,1058329179685568513
10.1073/pnas.1515528113,Medicine_tweet_142,Cost-effectiveness of #hpv #vaccines: ,"Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine.",Cost-effectiveness of #hpv #vaccines: ,"Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders. Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine. Both of these vaccines are highly efficacious against HPV-16 and HPV-18 and are partially efficacious against other non-vaccine-targeted oncogenic serotypes .","[1.0, 4.0, 5.0, 4.0, 4.0]",Medicine,train,4.0,tweets,722389929796304896
10.1186/s13059-018-1434-0,Medicine_tweet_143,Pretty convincing evidence of negative selection detectable in cancer exomes in contrast to Martincorena et al Cell 2017. Nice eg in TERT w +ve selection in promoter but -ve selection in exons. Makes good sense! ,"In summary, the presented evidence supports a major role of negative selection in cancer evolution, which has been neglected in most studies, and ultimately challenges the current paradigm of an exclusive role of positive selection in cancer.",Pretty convincing evidence of negative selection detectable in cancer exomes in contrast to Martincorena et al Cell 2017. Nice eg in TERT w +ve selection in promoter but -ve selection in exons. Makes good sense! ,"Interestingly, AP-1 is essential for MHC complex I downregulation and immune escape upon HIV infection . In summary, the presented evidence supports a major role of negative selection in cancer evolution, which has been neglected in most studies, and ultimately challenges the current paradigm of an exclusive role of positive selection in cancer. These studies help to shed light upon the mechanisms underlying immune evasion and provide insights for improving cancer immunotherapies in the future.","[4.0, 5.0, 3.0, 3.0]",Medicine,train,3.75,tweets,1003045321730076673
10.1001/jama.2015.1693,Medicine_tweet_144,Study in @username on #stents vs meds for intracranial stenosis  in @username ,"The 1-year primary outcome of stroke or hard TIA occurred in more patients in the stent group (21/58; 36.2% [95% CI, 24.0-49.9]) vs the medical group (8/53; 15.1% [95% CI, 6.7-27.6]) (P = .02).",Study in @username on #stents vs meds for intracranial stenosis  in @username ,"Intracranial hemorrhage within 30 days occurred in more patients in the stent group (5/58; 8.6% [95% CI, 2.9%-19.0%]) vs none in the medical group (95% CI, 0%-5.5%) (P = .06). The 1-year primary outcome of stroke or hard TIA occurred in more patients in the stent group (21/58; 36.2% [95% CI, 24.0-49.9]) vs the medical group (8/53; 15.1% [95% CI, 6.7-27.6]) (P = .02). Worsening of baseline disability score (modified Rankin Scale) occurred in more patients in the stent group (14/58; 24.1% [95% CI, 13.9%-37.2%]) vs the medical group (6/53; 11.3% [95% CI,.0%]) (P = .09).The EuroQol-5D showed no difference in any of the 5 dimensions between groups at 12-month follow-up.","[3.0, 1.0, 1.0, 3.0, 5.0]",Medicine,train,1.0,tweets,580482974388482048
10.1001/jama.2014.15690,Medicine_tweet_145,Aspirin - another drug that doesn't seem to make much difference in heart disease prevention in persons at risk ,"The 5-year cumulative primary outcome event rate was not significantly different between the groups (2.77% [95% CI, 2.40%-3.20%] for aspirin vs 2.96% [95% CI, 2.58%-3.40%] for no aspirin; hazard ratio [HR], 0.94 [95% CI, 0.77-1.15]; P = .54).",Aspirin - another drug that doesn't seem to make much difference in heart disease prevention in persons at risk ,"Patients with an occurrence of nonfatal stroke totaled 114 in the aspirin group and 108 in the no aspirin group; of nonfatal myocardial infarction, 20 in the aspirin group and 38 in the no aspirin group; of undefined cerebrovascular events, 3 in the aspirin group and 5 in the no aspirin group. The 5-year cumulative primary outcome event rate was not significantly different between the groups (2.77% [95% CI, 2.40%-3.20%] for aspirin vs 2.96% [95% CI, 2.58%-3.40%] for no aspirin; hazard ratio [HR], 0.94 [95% CI, 0.77-1.15]; P = .54). Aspirin significantly reduced incidence of nonfatal myocardial infarction (0.30 [95% CI, 0.19-0.47] for aspirin vs 0.58 [95% CI, 0.42-0.81] for no aspirin; HR, 0.53 [95% CI, 0.31-0.91]; P = .02) and transient ischemic attack (0.26 [95% CI, 0.16-0.42] for aspirin vs 0.49 [95% CI, 0.35-0.69] for no aspirin; HR, 0.57 [95% CI, 0.32-0.99]; P = .04), and significantly increased the risk of extracranial hemorrhage requiring transfusion or hospitalization (0.86 [95% CI, 0.67-1.11] for aspirin vs 0.51 [95% CI, 0.37-0.72] for no aspirin; HR, 1.85 [95% CI, 1.22-2.81]; P = .004).","[4.0, 5.0, 5.0, 1.0, 4.0]",Medicine,train,5.0,tweets,548775937345859586
10.1016/j.mito.2018.08.001,Medicine_tweet_146,"Dense article about the connection between disruption of cell function &amp; chronic illness. I never thought of the role that mitochondria play in disease prevention.  

",This switch in bioenergetics is protective to cells when capillaries have been disrupted and the availability of oxygen for aerobic metabolism is compromised.,"Dense article about the connection between disruption of cell function &amp; chronic illness. I never thought of the role that mitochondria play in disease prevention.  

","With M1 polarization, energy-coupled mitochondrial oxygen consumption drops, and cellular energy production switches to glycolysis and lactate production. This switch in bioenergetics is protective to cells when capillaries have been disrupted and the availability of oxygen for aerobic metabolism is compromised. This treatment causes cells to enter CDR1, decreasing mitochondrial oxidative phosphorylation and increasing glycolysis.","[3.0, 2.0, 2.0, 2.0, 1.0]",Medicine,train,2.0,tweets,1038881989355433984
10.1038/s41467-018-08278-4,Medicine_tweet_147,Science is pretty awesome. Some VERY interesting work regenerating limbs in mice. Still a LONG way to go for this to be used in humans though. ,These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound.,Science is pretty awesome. Some VERY interesting work regenerating limbs in mice. Still a LONG way to go for this to be used in humans though. ,Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint. These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound. Transient treatment of the amputation wound with BMP induces formation of an endochondral ossification center that organizes the regeneration response of the amputated stump bone .,"[3.0, 4.0, 3.0, 3.0]",Medicine,train,3.25,tweets,1094360043821154305
10.1001/jamapsychiatry.2015.0500,Medicine_tweet_148,"Treatment of Young People With Antipsychotic Medications  Il faudra changer,pas antipsy mais anti-badboys!!!","Young adults treated with antipsychotics were more frequently diagnosed as having depression, bipolar disorder, and anxiety disorder than ADHD.","Treatment of Young People With Antipsychotic Medications  Il faudra changer,pas antipsy mais anti-badboys!!!","Consistent with clinical diagnoses suggesting that antipsychotics are primarily used to manage impulsive or aggressive behaviors in children associated with ADHD, 27 the highest rate of antipsychotic treatment was in adolescent boys, approximately half of whom also filled prescriptions for stimulants. Young adults treated with antipsychotics were more frequently diagnosed as having depression, bipolar disorder, and anxiety disorder than ADHD. The single year of age and sex patterns of antipsychotic use offers clues to clinical and social determinants of community antipsychotic prescribing practices.","[2.0, 1.0, 4.0, 3.0]",Medicine,train,2.5,tweets,616299951719620608
10.1038/s41467-018-08278-4,Medicine_tweet_149,Bone and joint regeneration at amputation wounds shown in a study on mice treated with growth factor bone morphogenetic proteins BMP2 and BMP9:   #mice #amputee #regenerate #digit #bone #joint,"In cavity-forming digits, the nodule is not next to the BMP9 bead and BrdU-labeled chondrocytes are not present, indicating that BMP9 does not stimulate chondrocyte proliferation (Supplementary Fig.",Bone and joint regeneration at amputation wounds shown in a study on mice treated with growth factor bone morphogenetic proteins BMP2 and BMP9:   #mice #amputee #regenerate #digit #bone #joint,"These data indicate that BMP9 stimulates the aggregation and differentiation of chondrocytes but their progression to hypertrophic chondrocytes is delayed compared to BMP2-treated digits . In cavity-forming digits, the nodule is not next to the BMP9 bead and BrdU-labeled chondrocytes are not present, indicating that BMP9 does not stimulate chondrocyte proliferation (Supplementary Fig. The absence of proliferating chondrocytes and delayed hypertrophic differentiation distinguishes the BMP9 response from BMP2 stimulation of endochondral ossification .","[1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,tweets,1094455041887531010
10.1001/jamainternmed.2017.7978,Medicine_tweet_15,#PreventingType2 #breastfeeding  @username  breastfeeding  duration is independently associated with lower incidence of diabetes. ,This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes.,#PreventingType2 #breastfeeding  @username  breastfeeding  duration is independently associated with lower incidence of diabetes. ,"There was no evidence of effect modification by race, GD, or parity. This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes. Further investigation is required to elucidate mechanisms that may explain this relationship.","[2.0, 5.0, 4.0, 4.0]",Medicine,train,3.75,tweets,985972143929380865
10.2337/dc12-2084,Medicine_tweet_150,Diet rich in omega 3 (best source = oily fish) could help preserve pancreatic function for kids with T1 #diabetes ,Our study suggests that long-chain omega-3 fatty acids may provide protection to the b-cell after clinical diagnosis of type 1 diabetes.,Diet rich in omega 3 (best source = oily fish) could help preserve pancreatic function for kids with T1 #diabetes ,"However, significantly reduced risk of development of islet autoimmunity was associated with increased intake of omega-3 fatty acids among youth genetically susceptible to development of type 1 diabetes (36), although continued follow-up did not reveal subsequent protection against incident type 1 diabetes (37). Our study suggests that long-chain omega-3 fatty acids may provide protection to the b-cell after clinical diagnosis of type 1 diabetes. Our results support further study of the potential role of branched-chain amino acids to enhance sustained insulin production in type 1 diabetes.","[4.0, 4.0, 5.0, 5.0, 4.0]",Medicine,train,4.4,tweets,370255745251815424
10.1016/j.drugalcdep.2013.12.012,Medicine_tweet_151,New DSM-V categories for alcohol use disorders could allow for better targeting of treatment ,"DSM-5-AUD has the advantage of shedding light on risky drinkers included in the ""use in larger amounts class"", allowing for preventive interventions, which will reach a large number of individuals.",New DSM-V categories for alcohol use disorders could allow for better targeting of treatment ,"The two symptomatic classes clearly represented the dimensionality of the new proposed AUD criteria, and could be more specifically targeted by different prevention or treatment strategies. DSM-5-AUD has the advantage of shedding light on risky drinkers included in the ""use in larger amounts class"", allowing for preventive interventions, which will reach a large number of individuals. As reported by nearly a quarter of all current alcohol users , this totals 11 criteria .","[5.0, 2.0, 3.0, 5.0]",Medicine,train,4.0,tweets,428611208711655424
10.4049/jimmunol.1502483,Medicine_tweet_152,"Interesting paper @username showing transfer of activated maternal Tcells from milk to spleen, thymus, sm intestine ","This mechanism is consistent with the observation that a significant proportion of transferred maternal cells: 1) had a memory phenotype; 2) were Ag-specific by tetramer staining; or 3) when in the spleen, responded to Ag by the production of appropriate cytokines.","Interesting paper @username showing transfer of activated maternal Tcells from milk to spleen, thymus, sm intestine ","The mechanisms by which CD4 + T cells can acquire MHCII seem to be fewer in mice than humans . This mechanism is consistent with the observation that a significant proportion of transferred maternal cells: 1) had a memory phenotype; 2) were Ag-specific by tetramer staining; or 3) when in the spleen, responded to Ag by the production of appropriate cytokines. Importantly, Umeshappa et al.","[2.0, 3.0, 3.0, 3.0, 4.0]",Medicine,train,3.0,tweets,763037797372555264
10.1016/j.jsams.2019.05.003,Medicine_tweet_154,"New @username position statement on #exercise #medicine in #cancer management: ""Appropriate exercise prescription for cancer patients needs to be targeted and individualised according to patient- and cancer-specific considerations"" @username @username  ","While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.","New @username position statement on #exercise #medicine in #cancer management: ""Appropriate exercise prescription for cancer patients needs to be targeted and individualised according to patient- and cancer-specific considerations"" @username @username  ","Overall, evidence supports that the implementation of exercise prescription brings with it reduced morbidity, improved function and quality of life, and potential for improved survival, with very low risk of harm. While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients. Appropriate exercise prescription for cancer patients needs to be targeted and individualised according to patient-and cancer-specific considerations.","[3.0, 2.0, 5.0, 2.0, 4.0]",Medicine,train,3.2,tweets,1128109518339002368
10.1001/jama.2018.7028,Medicine_tweet_155,"""Are psychiatric reactions induced by trauma or other life stressors associated with subsequent risk of autoimmune disease?""
The answer is yes.
Stress&gt;chronic overstimulation sympathetic nervous system&gt;inflammation. 
That's exactly… ","In addition, among patients with PTSD specifically, persistent use of SSRIs throughout the first year after diagnosis was associated with attenuated risk of autoimmune disease.","""Are psychiatric reactions induced by trauma or other life stressors associated with subsequent risk of autoimmune disease?""
The answer is yes.
Stress&gt;chronic overstimulation sympathetic nervous system&gt;inflammation. 
That's exactly… ","These associations were independent of history of other psychiatric disorders and became stronger with the presence of co-occurring psychiatric comorbidities. In addition, among patients with PTSD specifically, persistent use of SSRIs throughout the first year after diagnosis was associated with attenuated risk of autoimmune disease. To our knowledge, this is the first study to address all stressrelated disorders and their associations with 41 distinct autoimmune diseases in men and women using both populationand sibling-based comparisons.","[3.0, 4.0, 2.0, 3.0]",Medicine,train,3.0,tweets,1009109630793015299
10.1073/pnas.1614389114,Medicine_tweet_156,"""Pride appears to be an elegantly engineered emotion""  via @username ","This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation.","""Pride appears to be an elegantly engineered emotion""  via @username ","Further, pride is specific to audience valuation: Emotions that co-activate with pride, such as happiness and excitement, do not track audience valuation uniquely and reliably. This suggests that pride, rather than other positive emotions, is distinctively involved in social valuation. Further evidence to demonstrate domain-specificity is needed, however.","[2.0, 2.0, 4.0, 4.0, 3.0]",Medicine,train,3.0,tweets,828855190463844352
10.1038/s41541-019-0118-4,Medicine_tweet_157,So excited about my recent publication in @username on a #VLP vaccine targeting #Alzheimers #publishorperish Check it out here: ,"Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be beneficial in preventing tau pathology and could be applicable to diverse human tauopathies, such as Alzheimer's disease (AD), frontotemporal dementia (FTD), traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE).",So excited about my recent publication in @username on a #VLP vaccine targeting #Alzheimers #publishorperish Check it out here: ,"Reduction in pathological consequences following this immunotherapy translated into improved cognitive function using well-established measurements of delay-dependent and spatial learning and memory tests. Therefore, we believe that this report provides compelling evidence that a VLP-based immunotherapy approach can be beneficial in preventing tau pathology and could be applicable to diverse human tauopathies, such as Alzheimer's disease (AD), frontotemporal dementia (FTD), traumatic brain injury (TBI), and chronic traumatic encephalopathy (CTE). In one example, pTau peptide (MAPT 9-8 , pS6/ 4) formulated with an adjuvant (Adju-Phos), induced taureactive antibodies, reduced MC1 and PHF1 positive neurons in the brains of TgP301L mice and rescued cognitive function.","[3.0, 4.0, 5.0, 5.0, 4.0]",Medicine,train,4.2,tweets,1135613881550745600
10.1038/s41467-018-05321-2,Medicine_tweet_158,"The inflammation homecoming queen, the NLRP3 inflammasome, is suppressed by sumoylation ",Signal II triggers loss of sumoylation of NLRP3.,"The inflammation homecoming queen, the NLRP3 inflammasome, is suppressed by sumoylation ","Taken together, these results indicate that NLRP3 is sumoylated in murine macrophages and human cells. Signal II triggers loss of sumoylation of NLRP3. Accordingly, we found that treatment with the bacterial toxin nigericin induced notable reduction of sumoylated NLRP3 ( Fig.","[1.0, 1.0, 1.0, 2.0]",Medicine,train,1.25,tweets,1024592685901000705
10.1186/s13027-016-0049-x,Medicine_tweet_159,P. gingivalis linked to esophageal cancer. ,"While the presence of P. gingivalis was not significantly associated with age, gender, or smoking history of the patients, the presence of P. gingivalis was positively related to differentiation, lymph node metastasis and the TNM stage of ESCC (p < 0.05).",P. gingivalis linked to esophageal cancer. ,"If we set the samples with IHC scores more than 1 as P. gingivalis positive, the sensitivity and specificity of IHC would be 94.3 and 96.6 %, respectively (Kappa = 0.882; p < 0.001, Additional file 2: Table S1), showing excellence concordance between IHC and qRT-PCR for the detection of P. gingivalis infection in the cancerous tissues of ESCC patients. While the presence of P. gingivalis was not significantly associated with age, gender, or smoking history of the patients, the presence of P. gingivalis was positively related to differentiation, lymph node metastasis and the TNM stage of ESCC (p < 0.05). A positive immunohistochemical signal for P. gingivalis was 90 % in the poorly differentiated tissues, which was significantly higher than that of well or moderately differentiated samples (p < 0.05) ( Table 5) .","[2.0, 5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,tweets,692034744603824128
10.1093/jnci/dju237,Medicine_tweet_16,Breastfeeding reduces risk of breast cancer in African Americans.  ,Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality.,Breastfeeding reduces risk of breast cancer in African Americans.  ,"The findings suggest that parous women who have not breastfed are at increased risk of ER-and triple-negative breast cancer. Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality. If so, the higher parity and lower prevalence of lactation in AA women relative to white women could be a contributor to the racial disparity in ER-cancer.","[2.0, 3.0, 3.0, 3.0, 4.0]",Medicine,train,3.0,tweets,515581109099565056
10.1542/peds.2013-2795,Medicine_tweet_160,"""@username:
Study finds that the incidence of diabetic ketoacidosis is high in youth with T1DM ","Among youth with type 2 diabetes, DKA was less common and decreased by ∼10% per year, suggesting improved detection or earlier diagnosis.","""@username:
Study finds that the incidence of diabetic ketoacidosis is high in youth with T1DM ","WHAT THIS STUDY ADDS: DKA in youth with type 1 diabetes remains a problem, with almost one-third presenting with DKA. Among youth with type 2 diabetes, DKA was less common and decreased by ∼10% per year, suggesting improved detection or earlier diagnosis. In youth with type 1 diabetes (n = 5615), the prevalence of DKA was high and stable over time (30.2% in 2002-2003, 29.1% in 2004-2005, and 31.1% in 2008-2010; P for trend = .42).","[2.0, 1.0, 1.0, 1.0, 3.0]",Medicine,train,1.6,tweets,451008669308579841
10.1016/j.jneb.2017.10.010,Medicine_tweet_161,"How mothers of kids w #obesity limit their intake of junk food.
Proud of this work with @username @username . @username ",The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research.,"How mothers of kids w #obesity limit their intake of junk food.
Proud of this work with @username @username . @username ","In addition, mothers' behavior may have been influenced by knowledge that they were participating in a study about feeding behaviors. The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research. Direct imperatives may have a healthy, adaptive role in approaches to feeding to prevent childhood obesity; they deserve careful consideration in future work.","[3.0, 5.0, 3.0, 4.0]",Medicine,train,3.75,tweets,942565180965359616
10.1007/s10484-015-9286-9,Medicine_tweet_163,Do women with sexual arousal disorders just need a little more giddyap in their heartbeat? ,"In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction.",Do women with sexual arousal disorders just need a little more giddyap in their heartbeat? ,"Women with below average HRV were significantly more likely to report sexual arousal dysfunction (p \ .001) and overall sexual dysfunction (p \ .001) than both women with average HRV and women with above average HRV. In conclusion, low HRV may be a risk factor for female sexual arousal dysfunction and overall sexual dysfunction. Given these findings, it is reasonable to expect ANS activity (indexed by HRV) may be related to women's self-reported, real-life sexual arousal function outside of the laboratory.","[4.0, 4.0, 4.0, 3.0]",Medicine,train,3.75,tweets,611926486220541952
10.1073/pnas.1306983110,Medicine_tweet_164,really neat! efficiency of jellyfish locomotion ,"We show that jellyfish exhibit a unique mechanism of passive energy recapture, which is exploited to allow them to travel 30% further each swimming cycle, thereby reducing metabolic energy demand by swimming muscles.",really neat! efficiency of jellyfish locomotion ,"Results from this study also have implications for bioinspired design, where low-energy propulsion is required. We show that jellyfish exhibit a unique mechanism of passive energy recapture, which is exploited to allow them to travel 30% further each swimming cycle, thereby reducing metabolic energy demand by swimming muscles. By accounting for large interspecific differences in net metabolic rates, we demonstrate, contrary to prevailing views, that the jellyfish (Aurelia aurita) is one of the most energetically efficient propulsors on the planet, exhibiting a cost of transport (joules per kilogram per meter) lower than other metazoans.","[3.0, 5.0, 4.0, 4.0, 3.0]",Medicine,train,3.8,tweets,387564723526713344
10.1007/s12110-018-9323-5,Medicine_tweet_165,A manipulated “win” at an athletic event raised men's testosterone level and self perceived mate value - and the willingness to engage in casual sex.  ,"Moreover, the contrasting changes in testosterone in winners and losers significantly predicted the changes in SPMV, Child Involvement, and M-P Trade-off in the groups following the manipulation.",A manipulated “win” at an athletic event raised men's testosterone level and self perceived mate value - and the willingness to engage in casual sex.  ,"Furthermore, winners exhibited a tendency toward increased sociosexuality, a measure of engaging in casual, uncommitted sexual relationships. Moreover, the contrasting changes in testosterone in winners and losers significantly predicted the changes in SPMV, Child Involvement, and M-P Trade-off in the groups following the manipulation. Both post-race testosterone and SPMV levels were significant correlates of the post-race outcome measures, whereas self-esteem was only correlated with men's likelihood of becoming involved with children, and consequently with the M-P Trade-off.","[2.0, 2.0, 2.0, 2.0]",Medicine,train,2.0,tweets,1027436143686688768
10.1073/pnas.1812786116,Medicine_tweet_166,Check ot my latest @username paper with @username and @username collaborators on the economic and demographic consequences of prenatal exposure to male co-twin. We hypothesize that testosterone is a major player in generating these altered trajectories ,"We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot differentiate in utero testosterone exposure from the postbirth socialization effects of being raised with a male co-twin.",Check ot my latest @username paper with @username and @username collaborators on the economic and demographic consequences of prenatal exposure to male co-twin. We hypothesize that testosterone is a major player in generating these altered trajectories ,"Consistent with some past studies, there was minimal evidence of any long-term impacts on males of exposure to a female co-twin (SI Appendix, Table S2 ). We do not have direct measures of prenatal testosterone exposure in our administrative data (e.g., from amniotic fluid), and models using all twin births cannot differentiate in utero testosterone exposure from the postbirth socialization effects of being raised with a male co-twin. The coefficients in this more stringent subsample (n = 583) are similar to those in the full sample (Figs.","[3.0, 2.0, 2.0, 2.0, 1.0]",Medicine,train,2.0,tweets,1107729116915224578
10.1136/esmoopen-2017-000250,Medicine_tweet_167,Evidence of accelerated #aging In #cancer survivors ,"We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects.",Evidence of accelerated #aging In #cancer survivors ,"We found multiple biological process of ageing at the cellular level and their association with cancer therapies, as well as with clinical effects. The direct effects of various chemotherapies and radiation on telomere length, senescent cells, epigenetic modifications and microRNA were found. Long-term follow-up of cancer survivors and research on prevention strategies should be pursued to increase the length and quality of life among the growing population of cancer survivors.","[3.0, 3.0, 1.0, 2.0, 4.0]",Medicine,train,2.6,tweets,943685169009086464
10.1038/s41598-017-08106-7,Medicine_tweet_168,Great paper on #neandertal adhesive technology:  #pyrotechnology #archaeology #experimentalarchaeology,Chemical and microscopic analysis of experimental material alongside archaeological remains may help illuminate which methods were likely used in the past by understanding the formation and thermal degradation of biomarkers (cf.,Great paper on #neandertal adhesive technology:  #pyrotechnology #archaeology #experimentalarchaeology,"However, the tar lumps themselves may be able to give further insights into the evolution of the technique used. Chemical and microscopic analysis of experimental material alongside archaeological remains may help illuminate which methods were likely used in the past by understanding the formation and thermal degradation of biomarkers (cf. While there are many potential methods of producing tar 26 , we have demonstrated that there are at least three successful aceramic solutions, ranging from low to high-tech.","[2.0, 3.0, 3.0, 1.0, 1.0]",Medicine,train,2.0,tweets,903342460331544576
10.1016/j.jcmg.2015.08.018,Medicine_tweet_169,"Adenosine and Non-Contrast #CMR T1 Mapping Differentiate Between Ischemic, Infarcted, Remote, and Normal Myocardium ","At rest, the remote myocardial T1 (955 AE 17 ms) was comparable to normal controls at 1.","Adenosine and Non-Contrast #CMR T1 Mapping Differentiate Between Ischemic, Infarcted, Remote, and Normal Myocardium ","10 patients showed evidence of previous myocardial infarction on LGE remote from the ischemic territories ( Table 2) . At rest, the remote myocardial T1 (955 AE 17 ms) was comparable to normal controls at 1. There was no significant stress dT1 reactivity in ischemic (0.2 AE 0.8%) or infarcted (0.2 AE 1.5%) myocardium compared to controls at 1.5-T (all p < 0.001).","[2.0, 2.0, 3.0]",Medicine,train,2.333333333333333,tweets,674992828527824896
10.1111/cdev.12344,Medicine_tweet_17,Elementary teachers' depression symptoms related to students' learning... ,"Teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement.",Elementary teachers' depression symptoms related to students' learning... ,"This depended on students' fall mathematics scores; students who began the year with weaker math skills and were in classrooms where teachers reported more depressive symptoms achieved smaller gains than did peers whose teachers reported fewer symptoms. Teachers' depressive symptoms were negatively associated with quality of CLE, and quality of CLE mediated the association between depressive symptoms and student achievement. The findings point to the importance of teachers' mental health, with implications for policy and practice.","[2.0, 4.0, 4.0, 4.0]",Medicine,train,3.5,tweets,566213087720914944
10.1542/peds.2017-1330,Medicine_tweet_170,Abstract: Teens who regularly use synthetic cannabinoids more likely 2 report polydrug use than marijuana-only users ,"Marijuana users who use other drugs in particular are at highest risk for currently using SCs, so particular focus needs to be paid to these individuals at high risk.",Abstract: Teens who regularly use synthetic cannabinoids more likely 2 report polydrug use than marijuana-only users ,"Although previous studies have revealed that marijuana users are at high risk for use, this study revealed risk factors among current marijuana users that increase risk of current use and higher-frequency use of SCs. Prevention needs to be focused primarily on marijuana users, especially marijuana users with risk factors discovered in this analysis. Marijuana users who use other drugs in particular are at highest risk for currently using SCs, so particular focus needs to be paid to these individuals at high risk.","[4.0, 4.0, 4.0]",Medicine,train,4.0,tweets,907598453706035201
10.1111/psyp.12228,Medicine_tweet_171,Pregnancy enhances the blood pressure response to music  #psychophysiology ,"Note, however, that this may not be a mechanism of prenatal cultural transfer specific to music, but that physiological responses in Enhanced response to music in pregnancypregnant women may be enhanced to acoustic stimulation in general, a question that is not addressed in the current study.",Pregnancy enhances the blood pressure response to music  #psychophysiology ,"Our finding suggests that the physiological response of the mother is enhanced with respect to a specific type of acoustical stimulus, namely, music, which may in turn partly underlie the strong physiological effects of music on the listener. Note, however, that this may not be a mechanism of prenatal cultural transfer specific to music, but that physiological responses in Enhanced response to music in pregnancypregnant women may be enhanced to acoustic stimulation in general, a question that is not addressed in the current study. Interestingly, the observed effects of music on the measured cardiac values (continuous blood pressure) are not directly related to valence, as has been previously speculated with respect to heart rate .","[4.0, 3.0, 4.0, 3.0, 3.0]",Medicine,train,3.4,tweets,506405445742112769
10.1377/hlthaff.2012.1030,Medicine_tweet_172,RT @username _Cesarean Delivery Rates Vary Widely Among US Hospitals.  … #ptsafety #healthcare #HIMSS13,"Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals.",RT @username _Cesarean Delivery Rates Vary Widely Among US Hospitals.  … #ptsafety #healthcare #HIMSS13,"Even for women with lower-risk pregnancies, in which more limited variation might be expected, cesarean rates varied fifteenfold, from 2.4 percent to 36.5 percent. Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals. Because Medicaid pays for nearly half of US births, government efforts to decrease variation are warranted.","[2.0, 3.0, 4.0, 4.0, 2.0]",Medicine,train,3.0,tweets,309002342546673664
10.1038/s41598-018-30933-5,Medicine_tweet_174,"Decisions, decisions. Our parrots made optimal choices when faced with an immediate food reward or a token that later on could be traded for a different value food. Find the paper here:  #Parrots ","In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food.","Decisions, decisions. Our parrots made optimal choices when faced with an immediate food reward or a token that later on could be traded for a different value food. Find the paper here:  #Parrots ","With this in mind, it is possible to hypothesise that the feeding specialists (the great green and the blue-throated macaws) might encounter a greater need for optimal decision-making as to where and when to go more often than feeding generalists (the African grey parrots and the blue-headed macaws), who may opportunistically take any food they encounter. In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food. Finally, two conditions presented a situation where there was no difference between the immediate and the future gain, so that the most economic decision was to consume the food immediately.","[4.0, 3.0, 3.0]",Medicine,train,3.333333333333333,tweets,1032214111097155584
10.1001/jamaoncol.2018.3701,Medicine_tweet_175,"If you find Gleason 6 #prostatecancer in men &gt;70 years of age, please ONLY offer active surveillance:
1) It's the right thing for the patient
2) It'll save Medicare ~$320 million
@username @username
","If we were to scale up our per-person cost to the national level using this more recent incidence data, the total 3-year costs to Medicare for diagnosing prostate cancer in men 70 years or older would be $1 billion, a decrease of approximately $200 million relative to the earlier incidence rates.","If you find Gleason 6 #prostatecancer in men &gt;70 years of age, please ONLY offer active surveillance:
1) It's the right thing for the patient
2) It'll save Medicare ~$320 million
@username @username
","29, 30 The age groups with the largest declines were ages 70 to 74 years (a decrease of 112 men per 100 000) and 75 to 79 years (a decrease of 120 men per 100 000). If we were to scale up our per-person cost to the national level using this more recent incidence data, the total 3-year costs to Medicare for diagnosing prostate cancer in men 70 years or older would be $1 billion, a decrease of approximately $200 million relative to the earlier incidence rates. Third, active surveillance has become a standard option for men with Gleason scores of 6 or lower.","[3.0, 3.0, 4.0, 3.0]",Medicine,train,3.25,tweets,1040337197596127233
10.1016/j.cell.2018.04.034,Medicine_tweet_176,"Can #CDK12 loss identify a subset (~7%) of mCRPC pts with #immunotherapy responsive tumors?  Provocative study from  #PCF #SU2C  International #ProstateCancer Dream Team 

article via:  
@username ","Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy.","Can #CDK12 loss identify a subset (~7%) of mCRPC pts with #immunotherapy responsive tumors?  Provocative study from  #PCF #SU2C  International #ProstateCancer Dream Team 

article via:  
@username ","We show that CDK12 mutants are genetically, transcriptionally, and phenotypically distinct from HRD and MMRD tumors. Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy. We detected aberrations of CDK12 in 25/360 of mCRPC patients (6.9%), 95% confidence interval (CI) [4.6%, 10 .2%] ( Figure 1A ).","[4.0, 2.0, 5.0, 4.0, 4.0]",Medicine,train,3.8,tweets,1016931473574768640
10.1038/s41598-018-26198-7,Medicine_tweet_177,RCT: 10 mins of stretching every day for 4 weeks reduced tumor volume by 52%  in mouse model of breast cancer. ,"Another important consideration is that, in this study, stretching was performed for 10 minutes once a day at ~25% strain, and we do not know whether a lower ""dose"" of stretching could be equally effective.",RCT: 10 mins of stretching every day for 4 weeks reduced tumor volume by 52%  in mouse model of breast cancer. ,"Because stretching tissues in one dimension likely results in some amount of perpendicular compression, this question is relevant to our model and will need to be examined. Another important consideration is that, in this study, stretching was performed for 10 minutes once a day at ~25% strain, and we do not know whether a lower ""dose"" of stretching could be equally effective. Determining the minimum effective amplitude, duration and frequency of stretching in animals will be important before translational studies in humans can be undertaken.","[3.0, 3.0, 4.0, 2.0]",Medicine,train,3.0,tweets,999306867720339460
10.1038/s41598-018-25573-8,Medicine_tweet_178,A customised #cancertreatment replicating ovarian #tumours inside chicken eggs ,"Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor.",A customised #cancertreatment replicating ovarian #tumours inside chicken eggs ,"Furthermore, we observed excellent tumor accumulation of the nanoparticles. Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.","[4.0, 2.0, 3.0, 4.0, 4.0]",Medicine,train,3.4,tweets,1005253169226682368
10.1001/jama.2018.7028,Medicine_tweet_179,"The association of stress disorders with increased risk of autoimmune diseases across 41 conditions @username 
 ","Restricting to participants with more than 5 years of followup, patients with stress-related disorders had a higher cumulative incidence of autoimmune diseases compared with their matched unexposed individuals across the follow-up period (eFigure3intheSupplement).","The association of stress disorders with increased risk of autoimmune diseases across 41 conditions @username 
 ","A score of zero shows no comorbidities; the higher the score, the more likely the predicted outcome will result in mortality or higher medical resource use. Restricting to participants with more than 5 years of followup, patients with stress-related disorders had a higher cumulative incidence of autoimmune diseases compared with their matched unexposed individuals across the follow-up period (eFigure3intheSupplement). Additional adjustment for medical surveillance level yielded somewhat lower point estimates (eTable 6 in the Supplement) while changing the definitions for history of other psychiatric disorders and autoimmune disease, and the extension of the lag-time period yielded similar results (eTables 7 and 8 in the Supplement).","[4.0, 4.0, 3.0, 5.0]",Medicine,train,4.0,tweets,1009096906830594048
10.1016/j.juro.2016.08.007,Medicine_tweet_18, | Jurology | Emotional distress increases the likelihood of receiving surgery among men with localized prostate ca…,The level of emotional distress in men shortly after diagnosis predicted a greater likelihood of choosing surgery over active surveillance., | Jurology | Emotional distress increases the likelihood of receiving surgery among men with localized prostate ca…,"Being older was associated with a lower likelihood of choosing surgery over active surveillance or radiation. The level of emotional distress in men shortly after diagnosis predicted a greater likelihood of choosing surgery over active surveillance. Importantly, this was true for men with low risk disease, for whom active surveillance may be a clinically viable option and the side effects of surgery or radiation might be unnecessary.","[4.0, 3.0, 5.0, 5.0, 5.0]",Medicine,train,4.4,tweets,762042945172279296
10.1098/rsbl.2014.0993,Medicine_tweet_180,It seems there is a plant that flowers only during a full moon in July. They're calling it the werewolf plant. ,"In the sympatric but wind-pollinated Ephedra distachya, pollination is not correlated to the full moon but occurs at approximately the same dates every year.",It seems there is a plant that flowers only during a full moon in July. They're calling it the werewolf plant. ,"Further, the spectacular reflection of the full-moonlight in the pollination drops is the only apparent means of nocturnal attraction of insects in these plants. In the sympatric but wind-pollinated Ephedra distachya, pollination is not correlated to the full moon but occurs at approximately the same dates every year. The lunar correlation has probably been lost in most species of Ephedra subsequent an evolutionary shift to wind pollination in the clade.","[2.0, 2.0, 4.0, 1.0, 1.0]",Medicine,train,2.0,tweets,584099194736115713
10.1001/jamapediatrics.2018.0302,Medicine_tweet_181,"""Question  Is vitamin D supplementation during pregnancy beneficial and safe for offspring?""  Answer: pretty much, yes. And some editorial comments:  and some other 'possible' links... ","Vitamin D supplementation was associated with higher neonatal vitamin D status (bolus-or regular-dose supplement and early or late timing were equally effective in attaining improvement in vitamin D levels), higher calcium levels, higher Apgar scores, greater neonatal skinfold thickness, greater weight (at birth, 3 months, 6 months, 9 months, and 12 months), and greater height (at 3 months, 9 months, and 12 months) in the offspring.","""Question  Is vitamin D supplementation during pregnancy beneficial and safe for offspring?""  Answer: pretty much, yes. And some editorial comments:  and some other 'possible' links... ","Vitamin D supplementation during pregnancy with lower doses (≤2000 IU/d) was associated with a reduced risk of fetal and neonatal mortality. Vitamin D supplementation was associated with higher neonatal vitamin D status (bolus-or regular-dose supplement and early or late timing were equally effective in attaining improvement in vitamin D levels), higher calcium levels, higher Apgar scores, greater neonatal skinfold thickness, greater weight (at birth, 3 months, 6 months, 9 months, and 12 months), and greater height (at 3 months, 9 months, and 12 months) in the offspring. Timing of vitamin D supplementation affected birth weight.","[3.0, 4.0, 5.0, 4.0, 5.0]",Medicine,train,4.2,tweets,1001561613021990914
10.1038/s41598-018-29793-w,Medicine_tweet_182,"The mix of bacteria that live inside your nos correlates with the type and severity of cold symptoms you develop❗  Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity  staph in your nose❗",Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation.,"The mix of bacteria that live inside your nos correlates with the type and severity of cold symptoms you develop❗  Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity  staph in your nose❗","The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection. Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation. We further found that rhinovirus infection did not have a major impact on the nasal microbiota.","[1.0, 1.0, 1.0, 2.0, 4.0]",Medicine,train,1.8,tweets,1045079620020838401
10.1001/jamapsychiatry.2015.0500,Medicine_tweet_183,Use of #antipsychotic meds increased among teens &amp; young adults from 2006-2010 but not among kids 12 or younger. ,This age profile refines earlier reports of steadily increasing rates of antipsychotic use across multiyear developmental categories of childhood to adolescence 28 to early adulthood.,Use of #antipsychotic meds increased among teens &amp; young adults from 2006-2010 but not among kids 12 or younger. ,"There was a rise in antipsychotic use during childhood that extended into adolescence for females, followed by a plateau and a decline during the transition to early adulthood. This age profile refines earlier reports of steadily increasing rates of antipsychotic use across multiyear developmental categories of childhood to adolescence 28 to early adulthood. 29 A peak in antipsychotic use among males aged 11 to 17 years fits with treatment of conduct problems that commonly occur during adolescence.","[4.0, 3.0, 4.0]",Medicine,train,3.6666666666666665,tweets,616285498454183936
10.1073/pnas.1504869112,Medicine_tweet_184,"Lianas increase tropical tree mortality, alter C allocation in leaves and stems. ","While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change.","Lianas increase tropical tree mortality, alter C allocation in leaves and stems. ","Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests. While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change. Aboveground tree carbon stocks in these 16 plots averaged 75.1 Mg C ha -1 , which was representative for other ∼60 year old forests in the neotropics .","[4.0, 3.0, 3.0, 3.0]",Medicine,train,3.25,tweets,659090123171213313
10.1016/j.jpeds.2017.10.028,Medicine_tweet_185,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence.",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Notably, this latter finding refers only to acts of violence and not frequency or severity, which is important, given research showing that female subjects may suffer more long-term negative physical and psychosocial consequences of teen dating violence. Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence. Finally, corporal punishment was associated with future physical perpetration of dating violence, even after controlling for demographic variables (ie, sex, ethnicity, age, parental education), as well as a history of childhood physical abuse.","[3.0, 4.0, 3.0, 1.0, 2.0]",Medicine,train,2.6,tweets,955029736874565632
10.1186/s13756-019-0493-7,Medicine_tweet_186,Implementation of antibiotic stewardship #AMS in different settings - results of an international survey  #aricjournal @username @username @username,"The impact of specialty level culture, and peer influence appears to be significant factors of antibiotic decision-making.",Implementation of antibiotic stewardship #AMS in different settings - results of an international survey  #aricjournal @username @username @username,"This study with participants representing 53 countries provides insights into the main components of antibiotic stewardship programmes in different countries and the key factors which influence the antibiotic decision-making of key healthcare professionals. The impact of specialty level culture, and peer influence appears to be significant factors of antibiotic decision-making. These data identify existing gaps in adequate training and education for staff involved in stewardship, and the need for greater participation of nurses and pharmacists to ensure effective and sustainable stewardship programmes.","[4.0, 3.0, 3.0, 3.0, 1.0]",Medicine,train,2.8,tweets,1095616726023192579
10.1038/s41467-018-05031-9,Medicine_tweet_187,"Prof Altmeyer and colleagues present an automated image-based cytometry method to quantify multiple cytotoxicity parameters in single cells and use it to study PARP inhibitors effect on cancer cells.

","However, compared to microscopy-based measurements the sensitivity of both western blot and flow cytometry was extenuated and the lack of high-resolution cell images represents an additional limitation that precludes analyses of PARPi-induced changes at the subcellular level (see below).","Prof Altmeyer and colleagues present an automated image-based cytometry method to quantify multiple cytotoxicity parameters in single cells and use it to study PARP inhibitors effect on cancer cells.

","Also flow cytometry revealed olaparib-induced γH2AX signaling in S-phase cells (Supplementary Figure 1g ). However, compared to microscopy-based measurements the sensitivity of both western blot and flow cytometry was extenuated and the lack of high-resolution cell images represents an additional limitation that precludes analyses of PARPi-induced changes at the subcellular level (see below). All compounds resulted in clearly detectable S-phase specific γH2AX signaling after just 4 h of exposure, with niraparib having the strongest and PJ-34 the weakest effect (Fig.","[4.0, 3.0, 1.0, 2.0, 3.0]",Medicine,train,2.6,tweets,1017623653981224961
10.1126/science.1244797,Medicine_tweet_189,[Science] [Research Article] Mars’ Surface Radiation Environment Measured with the Mars Science Laboratory’s C... ,The RAD surface measurements provide a baseline for inferring the flux in these more shielded environments (by validating and anchoring transport models) and thus the foundation for understanding the limits to preservation of organic matter in the soil and rocks of Gale crater.,[Science] [Research Article] Mars’ Surface Radiation Environment Measured with the Mars Science Laboratory’s C... ,"The radiation environment on Mars may also play a key role in the chemical alteration of the regolith and martian rocks over geologic time scales, affecting the preservation of organics, including potential organic biosignatures of the ancient martian environment . The RAD surface measurements provide a baseline for inferring the flux in these more shielded environments (by validating and anchoring transport models) and thus the foundation for understanding the limits to preservation of organic matter in the soil and rocks of Gale crater. The GCR dose rate can be seen to vary between 180 and 225 microgray (mGy)/ day, owing to the combined effects of diurnal variations from atmospheric pressure changes, Mars seasonal variations at Gale crater, and heliospheric structure variability due to solar activity and rotation.","[3.0, 1.0, 2.0]",Medicine,train,2.0,tweets,426450798227111937
10.1001/jamapediatrics.2018.0302,Medicine_tweet_19,"Study: ""Vitamin D supplementation during pregnancy is associated with a reduced risk of SGA and improved infant growth without risk of fetal or neonatal mortality or congenital abnormality."" ",Vitamin D supplementation with doses of 2000 IU/d or lower during pregnancy may reduce the risk of fetal or neonatal mortality.,"Study: ""Vitamin D supplementation during pregnancy is associated with a reduced risk of SGA and improved infant growth without risk of fetal or neonatal mortality or congenital abnormality."" ",CONCLUSIONS AND RELEVANCE Vitamin D supplementation during pregnancy is associated with a reduced risk of SGA and improved infant growth without risk of fetal or neonatal mortality or congenital abnormality. Vitamin D supplementation with doses of 2000 IU/d or lower during pregnancy may reduce the risk of fetal or neonatal mortality. Low vitamin D level status during pregnancy may expose the offspring to a suboptimal nutritional environment during critical phases of fetal development and may have long-term effects on offspring health outcomes.,"[5.0, 5.0, 4.0, 4.0, 4.0]",Medicine,train,4.4,tweets,1001608339808108544
10.1001/jamainternmed.2017.7720,Medicine_tweet_190,Cardiovascular Risk and Inhaled Long-Acting Bronchodilators ,"Individual LABA agents, LAMA dosage forms, and concomitant COPD regimens did not differ in the CVD risks.",Cardiovascular Risk and Inhaled Long-Acting Bronchodilators ,"New LABA and LAMA use in COPD was associated with a 1.50-fold (95% CI, 1.35-1.67; P < .001) and a 1.52-fold (95% CI, 1.28-1.80; P < .001) increased cardiovascular risk within 30 days of initiation, respectively, whereas the risk was absent, or even reduced with prevalent use. Individual LABA agents, LAMA dosage forms, and concomitant COPD regimens did not differ in the CVD risks. The risk persisted in an alternative case-crossover study and remained across subgroups without CVD history or prior exacerbations.","[2.0, 2.0, 3.0, 3.0, 2.0]",Medicine,train,2.4,tweets,985109449538002944
10.1037/a0014755,Medicine_tweet_192,The social costs of emotional suppression ,"An important topic for future studies will be to further examine factors that lead to changes in suppression, including both features of the environment that may affect all individuals similarly and construal processes that may vary from one individual to the next.",The social costs of emotional suppression ,"Variance in the dynamic component of suppression may reflect differences in how the transition was construed-as a traumatic separation by some and as an exciting social opportunity by others. An important topic for future studies will be to further examine factors that lead to changes in suppression, including both features of the environment that may affect all individuals similarly and construal processes that may vary from one individual to the next. Although we did not reassess suppression at the end of the fall term, indirect evidence suggests that changes in suppression may have endured.","[2.0, 1.0, 1.0, 4.0]",Medicine,train,1.0,tweets,440321643551129600
10.1098/rspb.2014.2120,Medicine_tweet_193,"""Foraging benefits of being fat"" // today in great research paper titles  ",Seals gradually became more buoyant as they increased their fat stores while foraging over the course of the migration.,"""Foraging benefits of being fat"" // today in great research paper titles  ","At the start of each migration, all 14 seals were negatively buoyant, as indicated by the negative drift rate values (figure 1; electronic supplementary material, figure S3 ). Seals gradually became more buoyant as they increased their fat stores while foraging over the course of the migration. All seals were still negatively buoyant at the end of the short foraging migration, but five of seven seals became neutrally buoyant by the end of the recording period during the long foraging migration, as indicated by the drift rates being zero (i.e.","[3.0, 1.0, 4.0, 3.0]",Medicine,train,2.75,tweets,530340253198848001
10.1038/s41746-018-0032-6,Medicine_tweet_194,Wearable tech: Activity monitor tracks wellbeing of advanced cancer patients ,"Furthermore, continuous activity monitoring during treatment could help predict and monitor treatment complications and allow for timely and appropriate intervention.",Wearable tech: Activity monitor tracks wellbeing of advanced cancer patients ,"Of additional importance is the possibility of combining objective activity monitoring data with electronically recorded PROs for the purpose of monitoring treatment tolerability and response in future clinical trials. Furthermore, continuous activity monitoring during treatment could help predict and monitor treatment complications and allow for timely and appropriate intervention. Although limited by its small size and short duration, our trial included participants of varying ECOG-PS and KPS ratings allowing for activity estimates in each of the performance status categories.","[4.0, 4.0, 4.0, 1.0, 5.0]",Medicine,train,2.0,tweets,1014848896416272390
10.1101/gad.263707.115,Medicine_tweet_195,"""longevity and epigenetics"" discovery science ","S4 ), extends life span, suggesting that trimethylated H3K36 specifically may regulate longevity.","""longevity and epigenetics"" discovery science ","Rph1 removes methyl groups from dimethylated and trimethylated H3K36, whereas Jhd1 does so from dimethyl and monomethyl states. S4 ), extends life span, suggesting that trimethylated H3K36 specifically may regulate longevity. Supporting the high-throughput histone mutant screen data, all of the H3K36 substitution mutants showed significantly shorter life spans (Fig.","[3.0, 3.0, 3.0]",Medicine,train,3.0,tweets,628643536741597184
10.1186/s40168-016-0167-0,Medicine_tweet_198,Microbial succession in an inflated lunar/Mars analog habitat during a 30-day…  #microbiome ,We conclude that it is critical to compare the microbiome of habitat without human occupation to habitat with human occupation since humans appeared to be the primary source of contamination in such habitats.,Microbial succession in an inflated lunar/Mars analog habitat during a 30-day…  #microbiome ,"Furthermore, the MARS 500 microbial analysis did not contain control, i.e., preoccupation bacterial diversity measurements, to compare the microbial accumulation as measured in this study. We conclude that it is critical to compare the microbiome of habitat without human occupation to habitat with human occupation since humans appeared to be the primary source of contamination in such habitats. Such a comparison may enable development of cleaning and maintenance protocols.","[2.0, 4.0, 2.0, 1.0, 4.0]",Medicine,train,1.0,tweets,738674927402811392
10.1001/jama.2019.1432,Medicine_tweet_2,"Is Diet Quality Associated With Later Risk for Dementia?
@username 

While usual limitations of observational studies like this apply, this analysis suggests eating a healthier diet assessed at midlife was not associated w/subsequent risk for #dementia.","In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia.","Is Diet Quality Associated With Later Risk for Dementia?
@username 

While usual limitations of observational studies like this apply, this analysis suggests eating a healthier diet assessed at midlife was not associated w/subsequent risk for #dementia.","Fourth, as with all observational studies, it was not possible to rule out residual confounding. In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia. The validity and reliability of this version of the FFQ in terms of nutrient and food consumption has been documented in detail both in this cohort and in another independent study in the United Kingdom.","[5.0, 4.0, 5.0, 4.0, 5.0]",Medicine,train,4.6,tweets,1105490748324102144
10.1007/s00127-012-0548-z,Medicine_tweet_20,"PMDD (síndrome pre-menstrual) was strongly and independently associated with non-fatal suicidal behaviors 
","These findings suggest that clinicians treating women with PMDD should assess and be vigilant for signs of suicidal behavior, and that clinicians might evaluate and treat the premenstrual symptoms of women who express suicidal ideation, plans, or attempts.","PMDD (síndrome pre-menstrual) was strongly and independently associated with non-fatal suicidal behaviors 
","In conclusion, this study is the first to demonstrate a strong, independent association between PMDD and suicidal ideation, plans, and attempts among a nationally representative sample of women. These findings suggest that clinicians treating women with PMDD should assess and be vigilant for signs of suicidal behavior, and that clinicians might evaluate and treat the premenstrual symptoms of women who express suicidal ideation, plans, or attempts. By targeting a gender-specific risk factor for non-fatal suicidal behavior, clinicians may be able to address a substantial public health problem among reproductive-aged women.","[4.0, 4.0, 4.0, 3.0]",Medicine,train,3.75,tweets,464347933207691264
10.1073/pnas.1403984111,Medicine_tweet_201,"#elephants dying from poaching for #ivory to east Asia reaches a tipping point: more killed than born (35,000 a yr)  ","At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China.","#elephants dying from poaching for #ivory to east Asia reaches a tipping point: more killed than born (35,000 a yr)  ","At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year. Preliminary data from 2013 indicate overharvesting continued.","[2.0, 3.0, 4.0, 3.0, 4.0]",Medicine,train,3.2,tweets,501656809741242368
10.1111/jth.13814,Medicine_tweet_202,Interesting how oncologic liver patients may be safely anti-coagulated s/p hepatectomy. &lt;6% complication rate with no fatalities reported in 124 patients @ MD Anderson. (Tag: @username) ,Conclusions: These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective.,Interesting how oncologic liver patients may be safely anti-coagulated s/p hepatectomy. &lt;6% complication rate with no fatalities reported in 124 patients @ MD Anderson. (Tag: @username) ,"The severe complication rate was 5.6%, with no 90-day mortalities. Conclusions: These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective. The intraoperative, postoperative and overall transfusion rates were 5.6%, 8.1%, and 10.5%, respectively.","[2.0, 3.0, 2.0, 4.0]",Medicine,train,2.75,tweets,936692744524910592
10.3945/ajcn.2010.29269,Medicine_tweet_205,@username FSA papers here  and  Same conclusions: no differences btwn organic and conventional,"This review does not address potential health effects of differences in contaminant content (such as herbicide, pesticide, and fungicide residues) of organically and conventionally produced foodstuffs or of potential wider environmental or occupational health effects of different agricultural practices.",@username FSA papers here  and  Same conclusions: no differences btwn organic and conventional,"Conclusion: From a systematic review of the currently available published literature, evidence is lacking for nutrition-related health effects that result from the consumption of organically produced foodstuffs. This review does not address potential health effects of differences in contaminant content (such as herbicide, pesticide, and fungicide residues) of organically and conventionally produced foodstuffs or of potential wider environmental or occupational health effects of different agricultural practices. Establishing the strength of the existing evidence base that relates to nutrition-related health benefits of organic food consumption will assist policymakers in the development of evidence-based statements on potential public-health gains or risks that result from organic food consumption and support consumers to make informed choices.","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,tweets,253490115580678144
10.1007/s00125-014-3400-z,Medicine_tweet_206,Increased risk for type 1 #diabetes following common entero-#virus infection in #children. #autoimmunity... ,Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection.,Increased risk for type 1 #diabetes following common entero-#virus infection in #children. #autoimmunity... ,"The HRs of type 1 diabetes in children with allergic rhinitis, bronchial asthma or either one of these atopic diseases showed more variation than in those children without these diseases. Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection. The results suggest that a preventive strategy, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.","[5.0, 4.0, 5.0, 5.0, 5.0]",Medicine,train,4.8,tweets,532442901603577856
10.1186/1742-2094-10-46,Medicine_tweet_208,"#journalofneuroinflammation
Focal brain inflammation and #autism ","We showed that mtDNA is significantly increased in the serum of young autistic children , who also had significantly increased serum level of NT ; this triggers mast cells to secrete mtDNA that acts as innate pathogen to stimulate mast cells and other immune cells, leading to auto-inflammation .","#journalofneuroinflammation
Focal brain inflammation and #autism ","There is also support for increased oxidative stress and some mitochondrial (mt) defects at least in subgroups of patients with ASD . We showed that mtDNA is significantly increased in the serum of young autistic children , who also had significantly increased serum level of NT ; this triggers mast cells to secrete mtDNA that acts as innate pathogen to stimulate mast cells and other immune cells, leading to auto-inflammation . We believe that ASD originate from immune perinatal insults that activate ASD susceptibility genes leading to focal encephalitis ( Table 2) .","[1.0, 5.0, 4.0, 3.0]",Medicine,train,3.0,tweets,322275784821702657
10.1038/d41586-018-04813-x,Medicine_tweet_209,"Editorial on ethical issues raised by models of human brain tissue - organoids, slices, chimeras 

""We do not think these difficult questions should halt research…. But to ensure success and social acceptance…. an ethical framework must be forged now""

","Is there a point at which we should be concerned about the welfare of brain surrogates or chimaeras, such that assigning someone loosely akin to a guardian or decision-maker for the brain surrogate might be warranted, beyond the researchers involved?","Editorial on ethical issues raised by models of human brain tissue - organoids, slices, chimeras 

""We do not think these difficult questions should halt research…. But to ensure success and social acceptance…. an ethical framework must be forged now""

","When people undergoing in vitro fertilization procedures choose to donate excess embryos to research, for instance, they are assured that these will not be used to create a baby. Is there a point at which we should be concerned about the welfare of brain surrogates or chimaeras, such that assigning someone loosely akin to a guardian or decision-maker for the brain surrogate might be warranted, beyond the researchers involved? Such an arrangement would be similar to the appointment of a guardian ad litem in custody disputes involving children in the United States (someone besides the parents who can represent the child's interests).","[4.0, 4.0, 1.0, 3.0]",Medicine,train,3.0,tweets,989210648969203713
10.1001/jamaoncol.2018.3701,Medicine_tweet_21,"""The estimated total 3-year cost to Medicare associated with the annual detection of prostate cancer in men 70 years or older is $1.2 billion.""  via @username And costs are only 1 harm domain of #overdiagnosis","CONCLUSIONS AND RELEVANCE There is substantial cost to the Medicare program associated with the diagnosis and treatment of localized prostate cancer among elderly men in the United States, despite the fact that these men are unlikely to die of prostate cancer.","""The estimated total 3-year cost to Medicare associated with the annual detection of prostate cancer in men 70 years or older is $1.2 billion.""  via @username And costs are only 1 harm domain of #overdiagnosis","IMPORTANCE Localized prostate cancer diagnosis and treatment among elderly men who are not likely to benefit represents a potential source of low-value health care services. CONCLUSIONS AND RELEVANCE There is substantial cost to the Medicare program associated with the diagnosis and treatment of localized prostate cancer among elderly men in the United States, despite the fact that these men are unlikely to die of prostate cancer. The majority of costs are related to treatment.","[4.0, 3.0, 3.0]",Medicine,train,3.333333333333333,tweets,1040337876423241728
10.1146/annurev-publhealth-031914-122421,Medicine_tweet_210,"RT @username: ""Policy Dilemmas in #Latino Health Care and Implementation of the #ACA"" ",Research into health care disparities affecting Latinos will likely change rapidly during the next two decades because of two important policy and sociodemographic changes.,"RT @username: ""Policy Dilemmas in #Latino Health Care and Implementation of the #ACA"" ","Care 535 patient, provider, and system factors that explains such disparities . Research into health care disparities affecting Latinos will likely change rapidly during the next two decades because of two important policy and sociodemographic changes. First, the implementation of the ACA will provide new topics of inquiry, such as the identification of new areas of disparities in health care including those between eligible and ineligible Latino populations (e.g., documented versus undocumented immigrants) as well as those within eligible populations.","[4.0, 2.0, 4.0, 4.0, 4.0]",Medicine,train,3.6,tweets,566612924777893889
10.1001/jamaneurol.2015.0475,Medicine_tweet_212,#CeliacDisease associated with increased risk of #neuropathy in a study of patients in #Sweden. ,"Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset.",#CeliacDisease associated with increased risk of #neuropathy in a study of patients in #Sweden. ,"We found an increased risk of neuropathy in patients with CD that persists after CD diagnosis. Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset. Our findings suggest that screening could be beneficial in patients with neuropathy.","[4.0, 2.0, 3.0, 3.0, 4.0]",Medicine,train,3.2,tweets,597844956791857153
10.1080/08870446.2014.918267,Medicine_tweet_213,Yes. Food ads do make you fatter.  #diet #nutrition #food,The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products.,Yes. Food ads do make you fatter.  #diet #nutrition #food,"In contrast to Experiment 1, exposure to television food advertising also affected ratings of desire to eat. The overweight and obese sample here reported a stronger desire to eat following priming with a series of television advertisements for food products than when primed with advertisements for non-food products. This suggests that in overweight and obese individuals, exposure to food commercials not only activates food-related cognitions, but also triggers a motivation to eat.","[5.0, 4.0, 5.0]",Medicine,train,4.666666666666667,tweets,505151800035389440
10.1186/s13054-014-0480-6,Medicine_tweet_214,Jean Chastre &amp; co review antibiotic stewardship as part of our #antibioticresistance series  #AntibioticDay #EAAD2014,"This strategy requires that initial antibiotic choices be guided by local antibiotic resistance patterns and laboratory test results (including Gram staining), rapidly yielding identities of likely responsible pathogens.",Jean Chastre &amp; co review antibiotic stewardship as part of our #antibioticresistance series  #AntibioticDay #EAAD2014,"In general, the first goal can be accomplished by rapidly identifying patients with infection and starting empirical therapy likely to treat the institution's most common etiological agents. This strategy requires that initial antibiotic choices be guided by local antibiotic resistance patterns and laboratory test results (including Gram staining), rapidly yielding identities of likely responsible pathogens. Therefore, every effort","[2.0, 4.0, 1.0, 4.0]",Medicine,train,2.0,tweets,534677591936884737
10.1126/science.1252496,Medicine_tweet_216,Examining the contents of an interstellar dust buster ,The remaining 25 so-called midnight tracks have trajectories that are consistent with an origin either in the interstellar dust stream or as ejecta from impacts on the lid of the sample return capsule (20) .,Examining the contents of an interstellar dust buster ,"Forty-six of the tracks are consistent in their trajectories with an origin as secondary ejecta from impacts on the aft solar panels, and this origin was confirmed for four tracks (12) (13) (14) (15) by the presence of cerium, a cosmically rare element present in the glass covering the spacecraft solar panels. The remaining 25 so-called midnight tracks have trajectories that are consistent with an origin either in the interstellar dust stream or as ejecta from impacts on the lid of the sample return capsule (20) . The ambiguity in origin of these 25 tracks is due to the articulation of the collector on its arm during the exposure (27) .","[4.0, 1.0, 2.0, 2.0]",Medicine,train,2.25,tweets,500005242964942848
10.1016/j.jsams.2019.05.003,Medicine_tweet_218,Hot off the press! How to do exercise prescription for cancer patients by the @username team  Well done! @username @username,"Conclusions: While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.",Hot off the press! How to do exercise prescription for cancer patients by the @username team  Well done! @username @username,"Additional specific exercise prescription considerations are provided for the presence of haematological, musculoskeletal, systemic, cardiovascular, lymphatic, gastrointestinal, genitourinary and neurological disease-and treatment-related concerns, as well as presence of co-morbid chronic disease. Conclusions: While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients. Targeted exercise prescription, which includes the provision of behaviour change advice and support, is needed to ensure greatest benefit (as defined by the patient) in the short and longer term, with low risk of harm.","[4.0, 1.0, 1.0, 3.0, 1.0]",Medicine,train,2.0,tweets,1128094890762498049
10.1016/j.neuron.2017.06.028,Medicine_tweet_219,Free featured- A perineuronal net protein dynamically gates PV+ interneuron function with effects on memory ,"Specifically, these properties seem to depend on BCAN expression in PV+ interneurons, as the PV+ cell-specific knockdown revealed a particularly strong and broad phenotype when compared to the full Bcan knockout that might be explained by the different timing of the experimental manipulations.",Free featured- A perineuronal net protein dynamically gates PV+ interneuron function with effects on memory ,"Indeed, the changes in spike shape and Kv3.1b clustering appear more directly related with the absence of BCAN. Specifically, these properties seem to depend on BCAN expression in PV+ interneurons, as the PV+ cell-specific knockdown revealed a particularly strong and broad phenotype when compared to the full Bcan knockout that might be explained by the different timing of the experimental manipulations. Likewise, the first PNNs are observed around P7 and their maturation continues until P28 .","[2.0, 4.0, 2.0]",Medicine,train,2.6666666666666665,tweets,893473876885327872
10.1016/j.cell.2016.09.056,Medicine_tweet_220,"The first ever #crystalstructure of a complete tetraspanin has just been published @username 
","The tetraspanin CD81 contains a large intramembrane cavity occupied by cholesterol, indicating the potential for functional modulation by small molecules.","The first ever #crystalstructure of a complete tetraspanin has just been published @username 
","Cholesterol binding appears to modulate CD81 activity in cells, suggesting a potential mechanism for regulation of tetraspanin function. The tetraspanin CD81 contains a large intramembrane cavity occupied by cholesterol, indicating the potential for functional modulation by small molecules. The development of specialized cell-cell interactions and new cell types likely selected for the duplication and differentiation of tetraspanins that evolved to effect specific functions.","[3.0, 4.0, 3.0, 3.0, 1.0]",Medicine,train,2.8,tweets,792005750843375617
10.1146/annurev-publhealth-031914-122421,Medicine_tweet_221,Study from @username Policy Dilemmas in #Latino Health Care and Implementation of the #ACA - PubMed - NCBI ,Focusing on efforts to improve delivery systems for Latinos will likely reduce disparities in patients' experiences and the quality of primary care received.,Study from @username Policy Dilemmas in #Latino Health Care and Implementation of the #ACA - PubMed - NCBI ,"Differences in the quality of care appear to be largely attributable to the fact that Latinos are cared for in settings where communication and the quality of care are not especially patient-centered . Focusing on efforts to improve delivery systems for Latinos will likely reduce disparities in patients' experiences and the quality of primary care received. Importantly, Latinas, in general, tend to have worse diet-related behaviors when compared with non-Latinas, including consuming more fast food, sugar-sweetened beverages, and fried potatoes .","[2.0, 3.0, 3.0, 2.0, 3.0]",Medicine,train,2.6,tweets,555820120975876096
10.1016/j.immuni.2019.05.007,Medicine_tweet_223,#ICYMI from the @username... Sera antibody repertoire analyses reveal mechanisms of broad and pandemic strain neutralizing responses after human #norovirus vaccination. @username  #organoids #enteroids ,Increased understanding of which capsid epitopes should be targeted to protect against different genotypes and of the impact of pre-exposure history on the elicitation of protective immunity after vaccination are important considerations in vaccine design and efficacy .,#ICYMI from the @username... Sera antibody repertoire analyses reveal mechanisms of broad and pandemic strain neutralizing responses after human #norovirus vaccination. @username  #organoids #enteroids ,"One antibody recognizes a neutralizing epitope conserved across three decades of pandemic strains and neutralizes virus in vitro, demonstrating that vaccination can elicit pandemicstrain neutralizing antibody responses in some individuals. Increased understanding of which capsid epitopes should be targeted to protect against different genotypes and of the impact of pre-exposure history on the elicitation of protective immunity after vaccination are important considerations in vaccine design and efficacy . Multivalent VLP immunization broadens the breadth of blockade antibodies produced after immunization of mice and humans .","[2.0, 1.0, 1.0, 3.0, 2.0]",Medicine,train,1.8,tweets,1142202817500856322
10.1126/science.1261713,Medicine_tweet_224,"huge amounts of methane producing in Mars atmosphere.  A hint to existence of life on a Mars?  answer in 3 hours
 ",Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit.,"huge amounts of methane producing in Mars atmosphere.  A hint to existence of life on a Mars?  answer in 3 hours
 ",(13) . Contradictions were noted between the locations of maxima reported from ground-based observations and maps inferred by PFS and TES from Mars orbit. The plume results (13) were questioned (22) on the basis of a possible misinterpretation from methane lines whose positions coincided with those of terrestrial isotopic 13 CH 4 lines.,"[2.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,tweets,545519854342901760
10.1111/acer.13408,Medicine_tweet_225,New Research: Findings from the Families on Track intervention pilot trial for children with fetal alcohol... ,Adapting existing interventions improves study efficiency and increases the potential for future dissemination.,New Research: Findings from the Families on Track intervention pilot trial for children with fetal alcohol... ,"Similar to several prior FASD interventions , results from this study document that existing interventions can be effective for children with FASD with appropriate adaptations. Adapting existing interventions improves study efficiency and increases the potential for future dissemination. Caregivers were also Bold data highlight statistically significant findings.","[1.0, 1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,tweets,857405378899828736
10.1016/j.neuropharm.2018.11.016,Medicine_tweet_226,"This study pairs #THC consumption &amp; stressful events - finds that this combination ""impairs fear extinction in adulthood."" This highlights a known connection between the endocannabinoid, memory, &amp; stress response systems, toward long-term exploration.  ","S7A ) and the IL (interaction THC x stress: F 1,22 = 5.66, p < 0.05) (Fig.","This study pairs #THC consumption &amp; stressful events - finds that this combination ""impairs fear extinction in adulthood."" This highlights a known connection between the endocannabinoid, memory, &amp; stress response systems, toward long-term exploration.  ","Simultaneous THC and stress adolescent exposure reduced the activity of the BLA (interaction THC x stress: F 1,23 = 9.52, p < 0.05) (Fig. S7A ) and the IL (interaction THC x stress: F 1,22 = 5.66, p < 0.05) (Fig. Interestingly, cFos expression was higher in adult animals exposed to THC and stress during the adolescence that did not undergo fear conditioning/extinction in both the BLA (p < 0.05) (Fig.","[3.0, 2.0, 1.0, 5.0, 1.0]",Medicine,train,1.0,tweets,1066394504939401217
10.1002/hec.3070,Medicine_tweet_228,Effects of taxing sugar sweetened beverages across different income groups ,"Thus the per capita, per year, weight loss as a result of the tax is almost six times greater for heavy drinkers relative to persons drinking at an average level.",Effects of taxing sugar sweetened beverages across different income groups ,"Using this conversion criteria a reduction of 16,087 kJ as a result of the SSB tax translates into a reduction in body weight of 0.44 Kg (16,087/36,500 Kj) per year at mean level of consumption. Thus the per capita, per year, weight loss as a result of the tax is almost six times greater for heavy drinkers relative to persons drinking at an average level. This is a significant positive effect, considering that heavy drinkers would be a major target group for any tax policy.","[3.0, 3.0, 2.0, 4.0]",Medicine,train,3.0,tweets,478921982768324608
10.1073/pnas.1716802115,Medicine_tweet_229,"How #obesity is limiting US life expectancy improvement, w/ ~200,000 excess deaths/year 
@username @username @username @username @username ",The effect of rising Max BMI is large relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration.,"How #obesity is limiting US life expectancy improvement, w/ ~200,000 excess deaths/year 
@username @username @username @username @username ","Results were robust to the inclusion of other variables in the model, to differences in how Max BMI was measured, and to how trends were evaluated. The effect of rising Max BMI is large relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration. The increase in Max BMI over the period 1988-2011 is estimated to have reduced life expectancy at age 40 by 0.9 years in 2011 (95% confidence interval 0.7-1.1 years) and accounted for 186,000 excess deaths that year.","[3.0, 1.0, 4.0, 3.0, 3.0]",Medicine,train,2.8,tweets,953305816630571008
10.1016/j.mayocp.2014.07.004,Medicine_tweet_23,Counseling and medication greatly increases smokers' chances of quitting ,"After adjusting for this confounder, we found that smokers who use a combination of specialist behavioral support and medication in their quit attempts had almost 3 times the odds of success than did those who used neither medication nor behavioral support.",Counseling and medication greatly increases smokers' chances of quitting ,"8 Still, smokers who used medication and behavioral support reported higher levels of urges to smoke than did smokers who tried to quit unaided. After adjusting for this confounder, we found that smokers who use a combination of specialist behavioral support and medication in their quit attempts had almost 3 times the odds of success than did those who used neither medication nor behavioral support. We also found that smokers who bought nicotine replacement therapy (NRT) over the counter with no behavioral support had similar odds of success at stopping as did those who stop without any aid.","[2.0, 5.0, 4.0, 4.0, 5.0]",Medicine,train,4.0,tweets,524192812556763136
10.1038/s41419-018-0765-9,Medicine_tweet_230,"RESEARCH: Scientists reverse aging-associated skin wrinkles and hair loss in a mouse model 

-","Instead, follicles contained predominantly keratinaceous debris with only a few developing hair shafts which were fragmented and malformed.","RESEARCH: Scientists reverse aging-associated skin wrinkles and hair loss in a mouse model 

-","6d ) in mtDNA-depleter compared with wild-type mice, these follicles were aberrant and did not produce normal hair shafts in mtDNA-depleter mice. Instead, follicles contained predominantly keratinaceous debris with only a few developing hair shafts which were fragmented and malformed. Thus, alopecia was not due to loss of hair follicles or cessation of cycling; rather, the follicles were dysfunctional and could not produce normal hair shaft or completely lost this capability.","[1.0, 2.0, 2.0, 2.0]",Medicine,train,1.75,tweets,1020479441678553088
10.1167/iovs.07-0804,Medicine_tweet_231,TIL There is a correlation between the intensity of reading and the likelihood of myopia. #science  ,"Of all near-work activities, only the time spent reading for pleasure was independently associated with SER after adjustment for age, sex, ethnicity, and school type (P trend ϭ 0.02, Table 2 ).",TIL There is a correlation between the intensity of reading and the likelihood of myopia. #science  ,"Less total near work was reported by the children of European Caucasian ethnicity than by those of East Asian ethnicity and by those attending public comprehensive schools than by those attending other school types (Table 1) . Of all near-work activities, only the time spent reading for pleasure was independently associated with SER after adjustment for age, sex, ethnicity, and school type (P trend ϭ 0.02, Table 2 ). In general, there was only a very weak correlation between SER and hours spent in near-work activities (correlation coefficient for all, r Յ Ϫ0.2; Table 3 ).","[2.0, 4.0, 2.0, 3.0, 5.0]",Medicine,train,3.2,tweets,185123055738159104
10.1080/02770903.2017.1299757,Medicine_tweet_232,Gr8 read in latest issue👌🏿Our work on asthma prevalence in London secondarySchools Interesting stats #datasaveslives  ,"Over a third (42.4%) of students prescribed a short-acting β2-agonist inhaler felt uncomfortable using it at school, and 29.2% (n = 173) reported not using this inhaler when wheezy.",Gr8 read in latest issue👌🏿Our work on asthma prevalence in London secondarySchools Interesting stats #datasaveslives  ,"Suboptimal asthma control was reported by 49.6% of students. Over a third (42.4%) of students prescribed a short-acting β2-agonist inhaler felt uncomfortable using it at school, and 29.2% (n = 173) reported not using this inhaler when wheezy. 56.4% (n = 220) of those with regular inhaled corticosteroids did not take them as prescribed, and 41.7% did not know what this inhaler was for.","[2.0, 2.0, 3.0, 2.0, 1.0]",Medicine,train,2.0,tweets,847165541085315072
10.1001/jamasurg.2014.2253,Medicine_tweet_233,.@username in @username: Less #surgery for pts w advanced #coloncancer. Study:  Article: ,"First, the decreasing rate of PTR could have been primarily the result of more effective systemic therapy or of greater reluctance among surgeons to operate on patients with asymptomatic stage IV CRC.",.@username in @username: Less #surgery for pts w advanced #coloncancer. Study:  Article: ,"Our study has several limitations. First, the decreasing rate of PTR could have been primarily the result of more effective systemic therapy or of greater reluctance among surgeons to operate on patients with asymptomatic stage IV CRC. The extent to which these factors contributed to the observed decreasing PTR rate is unknown.","[1.0, 4.0, 4.0, 3.0, 2.0]",Medicine,train,2.8,tweets,555860229293092865
10.1038/s41467-018-07418-0,Medicine_tweet_235,Interested in deep-sea microbes? Then check out our newest work on microbes living in hydrothermal sediments in Guaymas Basin.  ,"We found indications for such plasticity in several bacterial genomes, especially within the Delta-and Gammaproteobacteria that might couple the reduction of sulfur with the oxidation of carbon, lipids or hydrocarbons.",Interested in deep-sea microbes? Then check out our newest work on microbes living in hydrothermal sediments in Guaymas Basin.  ,"Respiratory processes were often partitioned among the community and only few genomes were encoding for full pathways. We found indications for such plasticity in several bacterial genomes, especially within the Delta-and Gammaproteobacteria that might couple the reduction of sulfur with the oxidation of carbon, lipids or hydrocarbons. While we cannot determine which processes are active, enhanced genotypic diversity might provide an additional adaptation strategy to variable environmental conditions.","[1.0, 1.0, 3.0, 3.0, 1.0]",Medicine,train,1.8,tweets,1067362653604069377
10.1016/j.childyouth.2014.05.001,Medicine_tweet_238,"Study done by #CHeSS affiliate D. Voisin of @username, which looks at risks for African American females in gangs. ","Major findings also indicated that low levels of parental monitoring, poor parental communication and housing instability were significantly associated with gang involvement.","Study done by #CHeSS affiliate D. Voisin of @username, which looks at risks for African American females in gangs. ","Similarly, our findings support earlier studies documenting that emotional processing ability has been associated with the quality of social interactions with both friends and family , and antisocial behavior and delinquency over time ). Major findings also indicated that low levels of parental monitoring, poor parental communication and housing instability were significantly associated with gang involvement. Our findings support social control theory .","[3.0, 4.0, 1.0, 3.0, 3.0]",Medicine,train,2.8,tweets,520657816575803392
10.1098/rsif.2019.0183,Medicine_tweet_239,"Our paper by @username, @username, Baddeley, @username &amp; @username on how to optimise camouflage and visibility using deep learning is now out in Royal Society Interface! 
We even got some pictures of tigers in it! #visualecology #colsci","The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid desert dichromat historical accounts of the military value of dichromatic observers and contemporary theories for the maintenance of visual pigment polymorphisms in many New World monkey species .","Our paper by @username, @username, Baddeley, @username &amp; @username on how to optimise camouflage and visibility using deep learning is now out in Royal Society Interface! 
We even got some pictures of tigers in it! #visualecology #colsci","Consequently this does not account for the difference between simulated dichromat and trichromat reaction times. The result, that trichromatic vision is more effective at breaking camouflage, seems to run counter to oft-quoted temperate forest trichromat temperate forest dichromat semi-arid desert trichromat semi-arid desert dichromat historical accounts of the military value of dichromatic observers and contemporary theories for the maintenance of visual pigment polymorphisms in many New World monkey species . This view seems to be confirmed by a brief survey of the literature.","[2.0, 3.0, 3.0, 2.0]",Medicine,train,2.5,tweets,1133664464132288512
10.1001/jamainternmed.2018.2259,Medicine_tweet_24,Tamulosin is often used in patients with kidney stones in the hope it will speed stone passage.  This RCT shows it is ineffective.  ,"Meaning For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage.",Tamulosin is often used in patients with kidney stones in the hope it will speed stone passage.  This RCT shows it is ineffective.  ,"Findings In this randomized clinical trial of 512 adults, the proportion achieving ureteral stone expulsion by 28 days was 50% with tamsulosin vs 47% with placebo, a nonsignificant difference. Meaning For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage. In the 11 cases for which this algorithm did not yield a clear result, the CT scans were individually reviewed and a consensus was reached.","[5.0, 4.0, 5.0]",Medicine,train,4.666666666666667,tweets,1008762116805808134
10.1016/j.cub.2014.12.023,Medicine_tweet_240,Nice one! MT @username: Our new marine extinctions paper  entirely dependent on @username &amp; @username,"We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ).",Nice one! MT @username: Our new marine extinctions paper  entirely dependent on @username &amp; @username,"16.8% marine), and proportions of predicted total species numbers (10.0% non-marine cf. We define 11 marine and eight non-marine groups as well assessed by the IUCN (of which six and seven, respectively, are also well described; Table 1 ). These contain 42.7% of all described and 98.8% of all assessed marine species and 25.5% of described and 96.9% of assessed non-marine species.","[1.0, 1.0, 5.0, 2.0, 3.0]",Medicine,train,1.0,tweets,561109259568820224
10.1073/pnas.1410186112,Medicine_tweet_243,"Study: Half of California's big trees have gone since 1930s, and oaks are muscling out evergreens .@username ","In the Sierra Nevada, increases of small trees of 63% and declines of large trees of 20% were found in resurveyed plots .","Study: Half of California's big trees have gone since 1930s, and oaks are muscling out evergreens .@username ","The differences in forest structure between the contemporary and historical datasets are also consistent with results of smaller studies that attempted to relocate and resurvey VTM plots. In the Sierra Nevada, increases of small trees of 63% and declines of large trees of 20% were found in resurveyed plots . Similarly, a 79% increase in tree density was found in the Transverse ranges of southern California, attributed to fire suppression .","[1.0, 2.0, 1.0, 3.0]",Medicine,train,1.75,tweets,557907665310212096
10.1093/eurpub/cky178,Medicine_tweet_244,"Our new paper shows link between cuts to public health budgets and falling vaccination rates in Italy 
 ",We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.,"Our new paper shows link between cuts to public health budgets and falling vaccination rates in Italy 
 ","Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles. We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage. In the worst affected regions, which faced up to 5% cuts, this would equate to a 2.5 percentage point fall in coverage.","[3.0, 5.0, 4.0, 4.0, 5.0]",Medicine,train,4.2,tweets,1039786038393270272
10.1098/rsbl.2013.0974,Medicine_tweet_245,Another universal human facial expression? The determination face  Original article: ,"Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we might expect human facial expressivity to exhibit some important differences from other primates.",Another universal human facial expression? The determination face  Original article: ,"Overall, physical similarity of the main facial expression configurations, however, may obscure important differences in how facial expression is actually used. Humans exhibit a motivation for, and level of, cooperation in their social interactions that is unique among primate species , and so, in this context, we might expect human facial expressivity to exhibit some important differences from other primates. The link between expression and emotion is not absolute , but in order for some level of honest communicative meaning to evolve, there must be an advantage to both sender and receiver .","[3.0, 2.0, 2.0, 2.0, 3.0]",Medicine,train,2.4,tweets,441471311387561984
10.1038/s41586-018-0731-9,Medicine_tweet_246,This seems like a rather important result in the structure of the quasar engine! ,"The angular size of each component scales with the observed optical flux 6 , making interferometry particularly well suited to exploring the physical origin of the broad-line region and to measuring black-hole masses in luminous quasars such as 3C 273, which are more representative of the supermassive black holes found in large samples out to high redshift.",This seems like a rather important result in the structure of the quasar engine! ,"Future observations could aim to measure a rotation curve and search for additional (for example, outflow) components and structural variability. The angular size of each component scales with the observed optical flux 6 , making interferometry particularly well suited to exploring the physical origin of the broad-line region and to measuring black-hole masses in luminous quasars such as 3C 273, which are more representative of the supermassive black holes found in large samples out to high redshift. These authors contributed equally: E. Sturm, J. Dexter.","[1.0, 1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,tweets,1067975907955171330
10.1038/ncomms16015,Medicine_tweet_247,First genetic variants identified for grip strength -  - nice work Cambridge team @username,"We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk.",First genetic variants identified for grip strength -  - nice work Cambridge team @username,"Grip strength is highly heritable (h 2 ¼ 30-65%) [10] . We also performed Mendelian randomization (MR) analyses, which showed no evidence for causality in the associations of grip strength with CVD or all-cause mortality, but were suggestive of a causal effect of muscular strength on fracture risk. Multiple novel loci are associated with grip strength.","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,tweets,885093865497264133
10.1001/jama.2015.7515,Medicine_tweet_248,"#Statin guidelines and #CV events, cost-effectiveness:  and  in @username ","Although our analyses suggest that adherence to new ACC/AHA statin eligibility guidelines may prove beneficial for the reduction of future cardiovascular events compared with using the ATP III guidelines, the absolute event risk of statinnoneligible adults is not much lower with the ACC/AHA guidelines (1.0%) compared with the ATP III guidelines (2.4%), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3% vs 6.9%).","#Statin guidelines and #CV events, cost-effectiveness:  and  in @username ","21 Analogous to their finding that participants with 50% or greater coronary stenosis were more frequently assigned statin therapy with the ACC/AHA guidelines than the ATP III guidelines (90% vs 60%, respectively), we show that those with high-risk CAC scores (>300) are more frequently allocated statin therapy with the ACC/AHA guidelines compared with the ATP III guidelines (5% vs 34%, respectively), and the HR among those with CAC scores greater than 300 for being statin eligible vs noneligible with the ACC/AHA guidelines is considerably higher than with the ATP III guidelines (HRs, 11 vs 3.6, respectively). Although our analyses suggest that adherence to new ACC/AHA statin eligibility guidelines may prove beneficial for the reduction of future cardiovascular events compared with using the ATP III guidelines, the absolute event risk of statinnoneligible adults is not much lower with the ACC/AHA guidelines (1.0%) compared with the ATP III guidelines (2.4%), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3% vs 6.9%). In addition, a risk-benefit analysis considering costs and potential adverse effects of statins, especially in patients with prediabetes and in lower-risk patients, is needed to provide a complete assessment of the effects of the change in statin eligibility guidelines on the health care system.","[2.0, 2.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,tweets,621069629876776964
10.3758/s13420-015-0194-x,Medicine_tweet_249,"#Learning&amp;Behavior: NC crows pay attention to where others forage, but do not copy their actions @username ","Whilst the task did not involve tool making, we assume that any social learning mechanism found to play a role in the acquisition of novel foraging behavior is also likely to play a role in the acquisition of tool-making behavior.","#Learning&amp;Behavior: NC crows pay attention to where others forage, but do not copy their actions @username ","We found no evidence that the choice of apparatus was influenced by the apparatus at which the interactions of others were observed suggesting the context specific effect generalized between apparatuses, as would be expected by stimulus enhancement, but not local Fig. Whilst the task did not involve tool making, we assume that any social learning mechanism found to play a role in the acquisition of novel foraging behavior is also likely to play a role in the acquisition of tool-making behavior. Since action-specific social learning mechanisms (e.g., imitation or emulation) would be required to account for the documented pattern of variation in New Caledonian crow tool types, that we found no action-specific effect in our diffusion experiment suggests that social learning resulting from observing another's tool-making activity is unlikely to explain tool type variation.","[2.0, 2.0, 2.0, 2.0, 3.0]",Medicine,train,2.2,tweets,633707789760753664
10.1001/jamapsychiatry.2015.0500,Medicine_tweet_25,Increased use of antipsychotic medication from 2006 to 2010 in adolescents and young adults  #Pharmacoepidemiology,"However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010).",Increased use of antipsychotic medication from 2006 to 2010 in adolescents and young adults  #Pharmacoepidemiology,"Most young people treated with antipsychotics in each age group filled 1 or more antipsychotic prescriptions that were written by a psychiatrist (57.9% of young children, 71.9% of older children, 77.9% of adolescents, and 70.4% of young adults in 2010) ( Table 2) . However, only a minority filled 1 or more antipsychotic prescriptions from a child and adolescent psychiatrist (29.3% of young children, 39.2% of older children, 39.2% of adolescents, and 14.2% of young adults in 2010). Younger children treated with antipsychotics were proportionately the least likely of the 4 age groups to have filled 1 or more antipsychotic prescriptions from a psychiatrist.","[3.0, 3.0, 2.0, 2.0, 3.0]",Medicine,train,2.6,tweets,620136776456384512
10.1098/rspb.2013.3172,Medicine_tweet_250,[2/2] Vaccination drivers (just two of many). Social norms:   health provider communication: ,"Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels.",[2/2] Vaccination drivers (just two of many). Social norms:   health provider communication: ,"The social learning rate k can also influence whether the population converges to no vaccine coverage or returns to full vaccine coverage, after a vaccine scare (figure 5). Vaccine scares can have long-term impacts on vaccine coverage, causing depressed coverage even after the perceived vaccine risk has returned to baseline levels. This is obvious in comparisons of the fitted model appearing in figure 1e,f to simulations of the same model, but where the pertussis vaccine scare never occurred (s ¼ 1, figure 6 ).","[2.0, 2.0, 2.0]",Medicine,train,2.0,tweets,435432048627810305
10.1001/jamadermatol.2018.0233,Medicine_tweet_252,This is an additional  pro that pushes the pro/con balance in favor of being married. #dermatology #aadmember #dermah12o ,Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care.,This is an additional  pro that pushes the pro/con balance in favor of being married. #dermatology #aadmember #dermah12o ,"Moreover, never married, divorced, and widowed patients are less likely to undergo SLNB for appropriate lesions. Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care. [8] Among patients with clinically localized melanoma, a wide range in melanoma-specific survival is characterized by T stage and ulceration status.","[1.0, 1.0, 3.0]",Medicine,train,1.6666666666666667,tweets,988383303920181248
10.1038/s41590-018-0068-4,Medicine_tweet_253,"New paper from our lab out today in @username showing how #vitaPAMP recognition via TLR8 promotes #TFHcell differentiation &amp; #vaccine responses. 
Free full text  
",These results indicated that the recognition of bacterial viability was an essential driver of vaccine-induced T FH cell and antibody responses in vivo.,"New paper from our lab out today in @username showing how #vitaPAMP recognition via TLR8 promotes #TFHcell differentiation &amp; #vaccine responses. 
Free full text  
","7g) , which demonstrated enhanced humoral immunity in response to the live vaccine. These results indicated that the recognition of bacterial viability was an essential driver of vaccine-induced T FH cell and antibody responses in vivo. A TLR8 polymorphism is associated with vaccine protection in humans.","[2.0, 1.0, 3.0, 3.0, 2.0]",Medicine,train,2.2,tweets,975784883288203264
10.1073/pnas.1606526113,Medicine_tweet_254,Climate change impacts in the Andes and the Himalayas: declining flows versus increasing extremes  l,Modeling studies at a high spatiotemporal resolution and degree of process complexity are crucial to assess the impact of climate change on the hydrological balance of high-altitude catchments and to refine the projections of the coarser-scale models .,Climate change impacts in the Andes and the Himalayas: declining flows versus increasing extremes  l,"Given the multitude of control factors, often acting at relatively small scales, current projections of global glacier change models do not constrain the mechanisms underlying the variations in river flow from high-altitude catchments well . Modeling studies at a high spatiotemporal resolution and degree of process complexity are crucial to assess the impact of climate change on the hydrological balance of high-altitude catchments and to refine the projections of the coarser-scale models . Model construction and calibration benefited from extensive shortterm field campaigns, which allowed overcoming the problem of data scarcity typical of poorly accessible high-altitude regions.","[1.0, 2.0, 3.0, 2.0]",Medicine,train,2.0,tweets,760208393365778432
10.1016/j.celrep.2013.07.022,Medicine_tweet_255,A positioning system that lets #regenerating cells know where they are in planarians  -- BLog: ,"Almost all planarian muscle cells express PCGs, suggesting a dual function: contraction and control of patterning.",A positioning system that lets #regenerating cells know where they are in planarians  -- BLog: ,"Almost all planarian muscle cells express PCGs, suggesting a dual function: contraction and control of patterning. PCG expression is dynamic in muscle cells after injury, even in the absence of neoblasts, suggesting that muscle is instructive for regeneration. We conclude that planarian regeneration involves two highly flexible systems: pluripotent neoblasts that can generate any new cell type and muscle cells that provide positional instructions for the regeneration of any body region.","[2.0, 1.0, 4.0, 4.0, 3.0]",Medicine,train,2.8,tweets,370226566527475712
10.1136/bmjopen-2013-002893,Medicine_tweet_256,Scots children most likely in UK to achieve PA recommendations but still only 53% do ,Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long-term health of our children.,Scots children most likely in UK to achieve PA recommendations but still only 53% do ,There are many opportunities to increase PA through sport but also in other areas. The full potential to boost PA will only be realised with a comprehensive policy response that increases time spent in more intense PA and decreases the time spent being sedentary. Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long-term health of our children.,"[3.0, 4.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,tweets,373048787780263936
10.1038/s41598-018-20760-z,Medicine_tweet_259,"Really interesting article about the precise fabrication of unidirectional molecular assemblies on a #graphene surface through the perturbation from fast #AFM tip scanning!
 ",This result indicates spontaneous random adsorption of the SDS molecules onto the graphene surface after the SDS solution injection.,"Really interesting article about the precise fabrication of unidirectional molecular assemblies on a #graphene surface through the perturbation from fast #AFM tip scanning!
 ","The height of the graphene increased by ~2.5 nm overall, and aggregates of various size appeared (see Supplementary Fig. This result indicates spontaneous random adsorption of the SDS molecules onto the graphene surface after the SDS solution injection. The subsequent intense scanning with a large force between the tip and sample (see Methods) drastically modified the SDS adsorption morphology; the initially adsorbed SDS molecules were removed, and new patterned structures emerged on the surface (see Supplementary Movie S1, Supplementary Note 1, and Supplementary Fig.","[4.0, 3.0, 2.0, 1.0, 1.0]",Medicine,train,2.2,tweets,1011610029991120896
10.1542/peds.2007-1894,Medicine_tweet_260,Vitamin D supplementation for babies: ,"However, a high melanin concentration can cause decreased vitamin D synthesis by preventing UV-B from reaching the stratum basale and spinosum of the epidermis, and this risk becomes manifest in situations of inadequate sun exposure.",Vitamin D supplementation for babies: ,"Therefore, it imparts an evolutionary advantage to dark-skinned people who live in areas of excessive sun exposure. However, a high melanin concentration can cause decreased vitamin D synthesis by preventing UV-B from reaching the stratum basale and spinosum of the epidermis, and this risk becomes manifest in situations of inadequate sun exposure. It is important to note that women of all populations have lighter skin than men, presumably because of increased vitamin D and calcium needs during pregnancy and lactation.","[1.0, 1.0, 1.0, 4.0, 3.0]",Medicine,train,2.0,tweets,343479748510490624
10.1111/j.1360-0443.2010.02899.x,Medicine_tweet_261,RT @username: Relation between Different Dimensions of #Alcohol Consumption & Burden of Disease - An Overview ,The variation in the effect of alcohol consumption on different types of stroke may be ascribed to the difference in the causes of haemorrhagic and ischaemic stroke.,RT @username: Relation between Different Dimensions of #Alcohol Consumption & Burden of Disease - An Overview ,"According to these meta-analyses, low to moderate alcohol consumption (one to two drinks per day) seemed to have a protective effect on ischaemic stroke, and then the risk curve turned upwards. The variation in the effect of alcohol consumption on different types of stroke may be ascribed to the difference in the causes of haemorrhagic and ischaemic stroke. Consequently, a pattern of irregular heavy drinking occasions should also have the same detrimental effects as for IHD.","[3.0, 2.0, 3.0, 3.0]",Medicine,train,2.75,tweets,193584254939176960
10.1001/jama.2013.276302,Medicine_tweet_262,Controversies about Accountable Care Organizations ACO  lower spending ..but not with consistently improved quality,"Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, 15,32,33 may be important.",Controversies about Accountable Care Organizations ACO  lower spending ..but not with consistently improved quality,"Conversely, cost-reducing spillovers present a free-riding problem to commercial insurers engaged in ACO contracts, since competing insurers with similar provider networks could offer lower premiums without incurring the costs of managing an ACO. Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, 15,32,33 may be important. Our study had several limitations.","[3.0, 1.0, 4.0, 1.0, 1.0]",Medicine,train,1.0,tweets,372694073179529216
10.1186/s13601-015-0055-x,Medicine_tweet_263,@username @username Latest Canadian study of where accidental exposures occur says this too. ,"Consequently, more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis.",@username @username Latest Canadian study of where accidental exposures occur says this too. ,"Conclusion: Despite increased awareness, accidental exposures continue to occur, mainly at home, and most are managed inappropriately by both health care professionals and caregivers. Consequently, more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis. Potential predictors for the Cox regression included sex, ethnicity, age at study entry, disease duration, source of recruitment (i.e., food allergy advocacy associations versus allergy clinics), other atopic conditions, severity of initial reaction to peanut, whether the child attended a school prohibiting peanut, and parental factors (i.e., living arrangement, age, level of education and employment).","[1.0, 1.0, 2.0, 1.0]",Medicine,train,1.25,tweets,586156349496684544
10.1038/s41467-018-04133-8,Medicine_tweet_264,"Congratulations Giancarlo for this really interesting paper! Unexpected behaviors in molecular transport through size-controlled #nanochannels down to the ultra-#nanoscale

@username @username @username @username #researchimpactEU","It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement.","Congratulations Giancarlo for this really interesting paper! Unexpected behaviors in molecular transport through size-controlled #nanochannels down to the ultra-#nanoscale

@username @username @username @username #researchimpactEU","3 and Supplementary Fig. It is important to note that obtaining a linear release profile for a molecule carrying a charge of sign opposite to that of the channel surfaces is trivial: as a matter of fact, it is a previously unreported achievement. Figure 2b exhibits release curves of anionic cefazolin, (3-aminosalicylic acid in Supplementary Fig.","[1.0, 2.0, 1.0, 1.0, 3.0]",Medicine,train,1.6,tweets,996674391961415680
10.1016/j.cell.2015.10.069,Medicine_tweet_265,Yeast can adapt to deletion of many essential genes; 'essentiality' may need to be redefined as a spectrum: ,"In particular, evolvable genes were enriched for components of subcellular compartments found only in eukaryotes (nucleus, endoplasmic reticulum, Golgi apparatus), but lacked core machineries common to all known cellular systems (mediators of DNA, mRNA and protein synthesis).",Yeast can adapt to deletion of many essential genes; 'essentiality' may need to be redefined as a spectrum: ,"Our data also pointed toward specific cellular functions being more evolvable than others. In particular, evolvable genes were enriched for components of subcellular compartments found only in eukaryotes (nucleus, endoplasmic reticulum, Golgi apparatus), but lacked core machineries common to all known cellular systems (mediators of DNA, mRNA and protein synthesis). This finding might imply that while some core functions are so central to cell survival as to prevent major evolutionary changes, it is possible that evolutionarily ''younger'' essential genes might have retained a certain degree of evolvability.","[2.0, 1.0, 2.0, 1.0, 4.0]",Medicine,train,2.0,tweets,671449802937380868
10.1073/pnas.1424293112,Medicine_tweet_266,.@username on pathogenic fungus on BC poplars.  ,"Most of the M. populorum secondary metabolite cluster proteins were found nested within a group of Eurotiomycetes fungi, including P. oxalicum, as expected under the hypothesis that the cluster was transferred from a Eurotiomycetes ancestor through a horizontal transfer event ( Fig.",.@username on pathogenic fungus on BC poplars.  ,"The striking conservation in synteny and gene sequence as well as the sporadic distribution of the full cluster in only two groups of the fungal phylogeny (Dothideomycetes and Eurotiales) raises the possibility that this cluster was acquired through horizontal gene transfer (HGT) (Fig. Most of the M. populorum secondary metabolite cluster proteins were found nested within a group of Eurotiomycetes fungi, including P. oxalicum, as expected under the hypothesis that the cluster was transferred from a Eurotiomycetes ancestor through a horizontal transfer event ( Fig. 2B ; Dataset S2; SI Appendix, Origin and evolutionary history of the chaetoglobosin-like gene cluster in M. populorum).","[1.0, 2.0, 1.0, 1.0, 1.0]",Medicine,train,1.2,tweets,573359896764145664
10.1186/s40479-014-0023-4,Medicine_tweet_267,"Sleep and BPD








",Future studies should concentrate on ambulatory polysomnographic recordings to investigate sleep in natural environments to detect sleep and dream complaints in people with nightmares.,"Sleep and BPD








","Therefore, nightmares should be seen as a distinct sleep disorder with specific symptoms that needs specific treatment. Future studies should concentrate on ambulatory polysomnographic recordings to investigate sleep in natural environments to detect sleep and dream complaints in people with nightmares. Furthermore, the difference between nightmare distress and nightmare frequency should be regarded which may lead to new insights concerning objective sleep measures.","[1.0, 3.0, 1.0, 1.0, 1.0]",Medicine,train,1.4,tweets,833963484970901504
10.1038/s41591-018-0013-y,Medicine_tweet_268,"Supporting brilliant Jose Vicente Sanchez-Mut @username to describe a new quantitative trait locus associated with Alzheimer’s disease. #meQTL #Alzheimer #GWAS. NOW OUT @username. 

","These findings suggest that in a particular genetic background, PM20D1 contributes to neuroprotection against AD.","Supporting brilliant Jose Vicente Sanchez-Mut @username to describe a new quantitative trait locus associated with Alzheimer’s disease. #meQTL #Alzheimer #GWAS. NOW OUT @username. 

","In line, genetically increasing or decreasing the expression of PM20D1 reduces and aggravates AD-related pathologies, respectively. These findings suggest that in a particular genetic background, PM20D1 contributes to neuroprotection against AD. When we re-analyzed these biologically and technically independent datasets by focusing exclusively on the comparison between samples from healthy controls and patients with advanced-stage AD, we noted that only one gene, PM20D1, which was previously described as a mQTL , consistently displayed promoter hypermethylation in patients with AD (hereafter referred to as AD samples) than in healthy controls in both studies (Fig.","[2.0, 3.0, 4.0]",Medicine,train,3.0,tweets,993748033690046464
10.1001/jamaophthalmol.2017.5470,Medicine_tweet_269,Study suggests #opticneuritis overdiagnosed in &gt;50% of cases and evaluates where diagnostic process might go wrong. ,"The most common diagnostic error was eliciting or interpreting critical elements of history, which occurred in 24 of 73 patients (33%) with alternative diagnoses.",Study suggests #opticneuritis overdiagnosed in &gt;50% of cases and evaluates where diagnostic process might go wrong. ,"The most common alternative diagnoses were headache and eye pain, functional visual loss, and other optic neuropathies, particularly nonarteritic anterior ischemic optic neuropathy. The most common diagnostic error was eliciting or interpreting critical elements of history, which occurred in 24 of 73 patients (33%) with alternative diagnoses. Other common errors included errors weighing or considering alternative diagnoses (23 patients [32%]), errors weighing or interpreting physical examination findings (15 patients [21%]), and misinterpreting diagnostic test results (11 patients [15%]).","[2.0, 3.0, 2.0, 3.0, 4.0]",Medicine,train,2.8,tweets,939540144989851649
10.1073/pnas.1323342111,Medicine_tweet_27,"Amygdala encodes subjective judgment of emotions shown in face stimuli, rather than simply their stimulus features: ",This suggests that amygdala neurons encode whole-face information and emotion independently.,"Amygdala encodes subjective judgment of emotions shown in face stimuli, rather than simply their stimulus features: ","We found 3 out of 24 (12.5%) fear-selective cells and 5 out of 17 (29.4%) happyselective cells are also whole-face-selective, a ratio of whole-face cells similar to that found in the entire population (36 out of 185, 19.5%). This suggests that amygdala neurons encode whole-face information and emotion independently. We found that face information conveyed by the eyes, but not the mouth region, modulated emotion-selective neuronal responses.","[4.0, 5.0, 5.0, 4.0, 4.0]",Medicine,train,4.4,tweets,535386739956006912
10.1016/j.ijnurstu.2014.02.007,Medicine_tweet_272,@username The only research I know in this area is on critical care &amp; level 1 trauma centres but not much. ,We found no evidence that the number of support staff working on the unit improves patients' survival chances even though their presence on the unit might have the effect of releasing clinical staff to care for patients.,@username The only research I know in this area is on critical care &amp; level 1 trauma centres but not much. ,"Nurses and doctors do seem to make a difference to patient outcomes in ICU. We found no evidence that the number of support staff working on the unit improves patients' survival chances even though their presence on the unit might have the effect of releasing clinical staff to care for patients. In this study, clear support emerged for the effect of workload.","[2.0, 1.0, 2.0, 3.0, 1.0]",Medicine,train,1.8,tweets,620479212097548288
10.1126/science.aap7778,Medicine_tweet_273,"WHY these behavioral progressions of H. sapiens emerged in the Glacial Maximum?
1) Oldest known evidence for BOW-ARROW dated to ~62,000 years in S. Africa

2) Oldest known CAVE PAINTINGS dated to ~65,000 years in W. Europe
 ","The implication is, therefore, that the artists were Neandertals.","WHY these behavioral progressions of H. sapiens emerged in the Glacial Maximum?
1) Oldest known evidence for BOW-ARROW dated to ~62,000 years in S. Africa

2) Oldest known CAVE PAINTINGS dated to ~65,000 years in W. Europe
 ","In this age range, Iberia was exclusively populated by Neandertals, as indicated by numerous diagnostic osteological remains, including articulated skeletons (28, 29) . The implication is, therefore, that the artists were Neandertals. This is a 1 cm 5 cm restricted and nonfigurative set of subjects and could represent the extension of Neandertal body art to the external world.","[1.0, 2.0, 3.0]",Medicine,train,2.0,tweets,989516975188664321
10.1001/jama.2009.1943,Medicine_tweet_274,@username Here is a link to one of the studies we cite: ,The present findings indicate that the efficacy of ADM treatment for depression varies considerably as a function of symptom severity.,@username Here is a link to one of the studies we cite: ,"Specific contrasts revealed that the regression coefficient (i.e., the slope representing the relationship between initial severity and change in symptoms) was more positive for each medication class relative to placebo: imipramine, F(1,707)=5.60, p=0.02; and paroxetine, F(1,707)=5.91, p=0.02. The present findings indicate that the efficacy of ADM treatment for depression varies considerably as a function of symptom severity. ""True"" drug effects (an advantage of ADM over placebo) were nonexistent-to-negligible among depressed patients with mild, moderate, and severe baseline symptoms, whereas they were large for patients with very-severe symptoms.","[1.0, 1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,tweets,94488214106144769
10.1038/s41598-017-18618-x,Medicine_tweet_275,"Apple cider vinegar has multiple antimicrobial properties on different microbial species, affecting microbe growth, suppressing mononuclear cytokine and phagocytic responses  ",The minimum dilution of ACV required for growth inhibition varied for each microbial species.,"Apple cider vinegar has multiple antimicrobial properties on different microbial species, affecting microbe growth, suppressing mononuclear cytokine and phagocytic responses  ","The minimum dilution of ACV required for growth inhibition varied for each microbial species. For C. albicans, a 1/2 ACV had the strongest effect, S. aureus, a 1/25 dilution ACV was required, whereas for E-coli cultures, a 1/50 ACV dilution was required (p < 0.05). Monocyte co-culture with microbes alongside ACV resulted in dose dependent downregulation of inflammatory cytokines (TNFα, IL-6).","[2.0, 3.0, 2.0, 2.0, 1.0]",Medicine,train,2.0,tweets,1022411479558094848
10.1377/hlthaff.2014.1428,Medicine_tweet_276,Some state vaccination laws contribute to greater exemption rates and disease outbreaks in the US -- @username ,"Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles.",Some state vaccination laws contribute to greater exemption rates and disease outbreaks in the US -- @username ,"Another component associated with lower exemption rates was the ability to be exempt from text) . Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles. This reduced exemption rates by 0.7 percent (Exhibit 3).","[2.0, 2.0, 1.0, 1.0]",Medicine,train,1.5,tweets,628571140647219201
10.1038/s41379-019-0249-1,Medicine_tweet_279,"@username @username @username It's an area of active research, but the numbers are small.
See e.g.


Note they used both an L1 test (SPF) *and* a p16 test to protect against false negatives caused by viral genome integration that drops the L1 gene.  (An e6/e7 test would be good too.)","HPV-negative tumors were more frequently of the non-squamous type (9/21, 43% vs. 37/193, 19%; p < 0.01) and showed negative p16 staining (9/21; 43% vs. 7/193; 4%; p < 0.01).","@username @username @username It's an area of active research, but the numbers are small.
See e.g.


Note they used both an L1 test (SPF) *and* a p16 test to protect against false negatives caused by viral genome integration that drops the L1 gene.  (An e6/e7 test would be good too.)","Twenty-one out of 214 tumors (10%) were negative for HPV DNA. HPV-negative tumors were more frequently of the non-squamous type (9/21, 43% vs. 37/193, 19%; p < 0.01) and showed negative p16 staining (9/21; 43% vs. 7/193; 4%; p < 0.01). HPV-negative tumors were more frequently diagnosed at advanced FIGO stage (19/21, 91% vs. 110/193, 57%; p < 0.01) and more frequently had lymph node metastases (14/21, 67% vs. 69/193, 36%; p < 0.01).","[2.0, 3.0, 2.0, 1.0, 1.0]",Medicine,train,1.8,tweets,1112854810674384896
10.1111/acer.12656,Medicine_tweet_28,Lower results on IQ tests are associated with higher consumption of alcohol.  ,"They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ.",Lower results on IQ tests are associated with higher consumption of alcohol.  ,"It should be noted that the authors report a skewed study population with regard to low socioeconomic position . They found a J-shaped association between frequency of drinking and IQ test results, where the daily drinkers had the lowest IQ. A higher IQ was associated with being a rare, an occasional, and a moderate drinker, whereas there was a lower IQ for being a former drinker compared with being a lifetime abstainer.","[5.0, 5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,tweets,569886674550964225
10.1007/s00401-017-1680-3,Medicine_tweet_280,Open Access UCL Research: Mixed pathologies including chronic traumatic encephalopathy account for dementia in ...  ,The findings of multiple foci of tau-positive ATs and NFTs with more intense in the sulcal depths of the frontal and temporal cortices with a perivascular distribution were diagnostic of CTE .,Open Access UCL Research: Mixed pathologies including chronic traumatic encephalopathy account for dementia in ...  ,"Examination of the brain showed moderate atrophy of the temporal lobes and hippocampi and fenestration of the septum pellucidum, with no evidence of metastatic tumour. The findings of multiple foci of tau-positive ATs and NFTs with more intense in the sulcal depths of the frontal and temporal cortices with a perivascular distribution were diagnostic of CTE . In addition, there was widespread tau pathology supportive of CTE with neuronal and glial inclusions in the superficial cortical layers.","[2.0, 4.0, 2.0, 1.0]",Medicine,train,2.25,tweets,851466787560542208
10.1542/peds.2014-2707,Medicine_tweet_281,The Great Sleep Recession  Maybe some quantitative easing required?,"Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts born in the early 1990s, were more likely to report regular $7 hours of sleep compared with all other adolescents.",The Great Sleep Recession  Maybe some quantitative easing required?,"Thus, these data indicate that adolescent sleep is declining across all age groups and major sociodemographic subgroups. Cohort effects were also observed for some subgroups, particularly in $7 hours of sleep for male subjects, white subjects, and those in urban areas; those in the earliest cohorts, as well as cohorts born in the early 1990s, were more likely to report regular $7 hours of sleep compared with all other adolescents. Third, we documented that girls are less likely to regularly report $7 hours of sleep and to feel they get adequate sleep, as are black/Hispanic adolescents and those in lower SES strata.","[1.0, 2.0, 2.0, 3.0]",Medicine,train,2.0,tweets,567235990394523648
10.1073/pnas.1313039111,Medicine_tweet_282,"The power of crowd-sourcing:  My favorite hobby, folding RNA,...done by 37,000 people.  ","These results show that an online community can carry out large-scale experiments, hypothesis generation, and algorithm design to create practical advances in empirical science.","The power of crowd-sourcing:  My favorite hobby, folding RNA,...done by 37,000 people.  ","These rules, distilled by machine learning into a new automated algorithm EteRNABot, also significantly outperform prior algorithms in a gauntlet of independent tests. These results show that an online community can carry out large-scale experiments, hypothesis generation, and algorithm design to create practical advances in empirical science. The initial 6-mo training period, called phase I, saw the EteRNA community engaging in six RNA design problems containing increasing numbers of nonhelical elements (bulges and multihelix junctions) and more complex topologies ( Fig.","[2.0, 1.0, 2.0, 3.0]",Medicine,train,2.0,tweets,428926849721184256
10.1073/pnas.1408439111,Medicine_tweet_285,New research on @username dynamic population mapping:  and video:  by @username et al.,This study demonstrates how data collected by mobile phone network operators can costeffectively provide accurate and detailed maps of population distribution over national scales and any time period while guaranteeing phone users' privacy.,New research on @username dynamic population mapping:  and video:  by @username et al.,"The global MP penetration Significance Knowing where people are is critical for accurate impact assessments and intervention planning, particularly those focused on population health, food security, climate change, conflicts, and natural disasters. This study demonstrates how data collected by mobile phone network operators can costeffectively provide accurate and detailed maps of population distribution over national scales and any time period while guaranteeing phone users' privacy. The methods outlined may be applied to estimate human population densities in lowincome countries where data on population distributions may be scarce, outdated, and unreliable, or to estimate temporal variations in population density.","[1.0, 3.0, 1.0, 1.0]",Medicine,train,1.5,tweets,527035715730046976
10.1002/pon.4156,Medicine_tweet_286,"Exercise improves memory in breast cancer survivors

New study:  ","Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI.","Exercise improves memory in breast cancer survivors

New study:  ","Survivors who reported higher levels of distress also reported higher levels of fatigue (β = 0.63). Finally, higher levels of distress (β = À0.31) and fatigue (β = À0.18) were associated with lower Frequency of Forgetting scores which is indicative of greater SMI. Additionally, the indirect paths from physical activity to SMI via exercise self-efficacy and distress, exercise self-efficacy and fatigue and exercise selfefficacy, distress and fatigue were all significant.","[4.0, 1.0, 2.0]",Medicine,train,2.0,tweets,751688955070976000
10.1542/peds.2013-3406,Medicine_tweet_287,"Prenatal SSRIs might increase susceptibility to #autism or developmental delays, but findings are inconsistent.  (£)","Adjusting, rather than restricting, for maternal mental health yielded similar findings.","Prenatal SSRIs might increase susceptibility to #autism or developmental delays, but findings are inconsistent.  (£)","The pattern was similar among boys in the anxiety/mood disorder subset, but with low precision (102 ASD, 29 DD, 50 TD). Adjusting, rather than restricting, for maternal mental health yielded similar findings. Results were similar, although attenuated.","[1.0, 3.0, 1.0, 2.0, 1.0]",Medicine,train,1.6,tweets,455744735857352704
10.1098/rspb.2013.1698,Medicine_tweet_288,Lab is starting to do sleep work: here we link perceptual consolidation with processes usually associated with memory ,"The average time spent in REM was negatively correlated with SWS duration, which, in turn, can explain the negative correlation that was found for SWS duration and adaptation and for low-frequency power in the delta and theta range and adaptation.",Lab is starting to do sleep work: here we link perceptual consolidation with processes usually associated with memory ,"Participants who exhibited high amounts of REM sleep also showed greater adaptation. The average time spent in REM was negatively correlated with SWS duration, which, in turn, can explain the negative correlation that was found for SWS duration and adaptation and for low-frequency power in the delta and theta range and adaptation. Adaptation was further predicted by spindle density of both slow and fast spindles, however in opposite ways.","[3.0, 3.0, 2.0, 2.0, 1.0]",Medicine,train,2.2,tweets,376419863214182400
10.1038/s41586-018-0347-0,Medicine_tweet_289,Quite excited to share our article on high-rate energy storage in niobium tungsten oxides in @username!! This has been a work in progress for roughly four years and involved seven different beamtimes @username and @username and PFG NMR! ,"Any Methods, including any statements of data availability and Nature Research reporting summaries, along with any additional references and Source Data files, are available in the online version of the paper at https://doi.org/10.1038/s416-018-0347-0.",Quite excited to share our article on high-rate energy storage in niobium tungsten oxides in @username!! This has been a work in progress for roughly four years and involved seven different beamtimes @username and @username and PFG NMR! ,"These criteria, which lead to extremely high power and energy densities (Fig. Any Methods, including any statements of data availability and Nature Research reporting summaries, along with any additional references and Source Data files, are available in the online version of the paper at https://doi.org/10.1038/s416-018-0347-0. 1, Supplementary Fig.","[1.0, 2.0, 1.0, 3.0, 2.0]",Medicine,train,1.8,tweets,1022171486340239360
10.1016/j.jtho.2016.01.011,Medicine_tweet_29,Metabolic phenotyping of plasma could be used to detect lung cancer in Belgian cohort. ,"In conclusion, this paper validates 1 H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between patients with lung cancer and controls.",Metabolic phenotyping of plasma could be used to detect lung cancer in Belgian cohort. ,"These findings indicate that lung cancer cells utilize at least some steps of the gluconeogenic pathway to adapt to low-glucose conditions as a result of insufficient blood flow. In conclusion, this paper validates 1 H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between patients with lung cancer and controls. Our findings indicate that metabolic alterations can already be detected in an early stage.","[5.0, 3.0, 3.0, 4.0, 5.0]",Medicine,train,4.0,tweets,704624845577969664
10.1186/s13058-018-1049-0,Medicine_tweet_290,Congratulations to @username  on latest #BreastCancer research publication. @username @username ,"This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD .",Congratulations to @username  on latest #BreastCancer research publication. @username @username ,"Improved techniques to assess the MRD population and their dormant or reactivating state will be key to identifying the risk of future metastasis despite undergoing standard treatment. This opens the way for testing new treatments that prevent metastasis by inducing/enforcing dormancy, and/or to eradicate MRD . These drugs will be tested in a clinical trial of prostate cancer patients at risk of developing metastasis (Mount Sinai IRB no.","[1.0, 1.0, 1.0, 1.0]",Medicine,train,1.0,tweets,1052288596449914885
10.1038/s41467-018-06824-8,Medicine_tweet_291,"NEW PAPER from fantastic postdoc Sarah Kocher (@username) now PI at @username on the genetic basis of social behavior in halictid bees (w great collabs: @username, Pierce, Yu, Rubin):   ","We estimated the nucleotide diversity per site (π) to be 0.002, and we did not find differences in genetic diversity among social forms (Supplementary Table 1 ; two-sample t-test; t 4 = −0.961, p = 0.391).","NEW PAPER from fantastic postdoc Sarah Kocher (@username) now PI at @username on the genetic basis of social behavior in halictid bees (w great collabs: @username, Pierce, Yu, Rubin):   ","Whole-genome resequencing data identified a total of 2,6,960 genetic variants among 143 individuals of L. albipes that passed our quality filters (see Methods; Supplementary Data 1). We estimated the nucleotide diversity per site (π) to be 0.002, and we did not find differences in genetic diversity among social forms (Supplementary Table 1 ; two-sample t-test; t 4 = −0.961, p = 0.391). As in honey bees , LD decays rapidly with physical distance:","[1.0, 1.0, 3.0, 1.0, 3.0]",Medicine,train,1.8,tweets,1052896612274589696
10.1001/jamainternmed.2016.0157,Medicine_tweet_292,Great talk on validation of a blood pressure app for your smartphone:  Conclusion: Recall the App. #epilifestyle16,"IBP systolic BP readings were within , 10, and 1 mm Hg of the standard BP measurement 24%, 44%, and 9% of the time, respectively, whereas respective proportions for diastolic BP were 26%, 48%, and 70%, correlating with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring.",Great talk on validation of a blood pressure app for your smartphone:  Conclusion: Recall the App. #epilifestyle16,"IBP underestimated higher BPs and overestimated lower BPs (Figure) . IBP systolic BP readings were within , 10, and 1 mm Hg of the standard BP measurement 24%, 44%, and 9% of the time, respectively, whereas respective proportions for diastolic BP were 26%, 48%, and 70%, correlating with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring. Spearman ρ was 0.44 (P < .001) for systolic BP and 0.41 (P < .001) for diastolic BP.","[3.0, 1.0, 2.0, 5.0]",Medicine,train,3.0,tweets,705098247971303424
10.1038/nature22346,Medicine_tweet_294,A Challenge to Lepton Universality in B Meson Decays. ,"A confirmation of these results would point to new particles or interactions, and could have profound implications for our understanding of particle physics.",A Challenge to Lepton Universality in B Meson Decays. ,"For purely leptonic B − decays, the standard model prediction of the total decay rate Γ, which depends critically on the lepton mass squared m ℓ 2 , is: One of the key assumptions of the standard model of particle physics is that the interactions of the charged leptons, namely electrons, muons and taus, differ only because of their different masses. A confirmation of these results would point to new particles or interactions, and could have profound implications for our understanding of particle physics. SM 0 05 0 10 4 Decays to the lower-mass charged leptons, e − and μ − , are strongly suppressed by spin effects and have not yet been observed.","[1.0, 1.0, 1.0, 1.0, 3.0]",Medicine,train,1.4,tweets,838940737831985154
10.1093/asj/sjw089,Medicine_tweet_295,"New in @username by @username, a free read:  #hairloss #hairtransplant #hair #oa ",This 49-year-old man is a poor candidate for leg hair extraction because of complete hair loss in most areas.,"New in @username by @username, a free read:  #hairloss #hairtransplant #hair #oa ","The author has observed that following scoring by the UPunch Rotor, a variable percentage of grafts is completely Figure 3 . This 49-year-old man is a poor candidate for leg hair extraction because of complete hair loss in most areas. In the areas with hair, the hair is also vellous-looking with densities below 8 per cm 2 .","[3.0, 2.0, 2.0, 2.0]",Medicine,train,2.25,tweets,737437256739377152
10.1016/j.physbeh.2009.12.026,Medicine_tweet_296,Hunger & Thirst: Issues in Measurement & #Prediction of Eating & Drinking ,This agrees with work in both animal models and humans ] that show about 70-75% of drinking occurs peri-prandially.,Hunger & Thirst: Issues in Measurement & #Prediction of Eating & Drinking ,"Otherwise, the peaks are highly synchronous. This agrees with work in both animal models and humans ] that show about 70-75% of drinking occurs peri-prandially. The weekday versus weekend differences in ingestive episodes highlight the importance of lifestyle and social custom on this activity .","[2.0, 3.0, 1.0, 2.0]",Medicine,train,2.0,tweets,170241073459892224
10.1001/jamacardio.2018.1511,Medicine_tweet_297,"17 years after publishing NRMI data on race based differences in statin use, not much has changed. Yet, this study provides new insights into why. Perceptions of CV Risk and Statin Drugs and Racial Differences in Statin Use  @username @username","Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention.","17 years after publishing NRMI data on race based differences in statin use, not much has changed. Yet, this study provides new insights into why. Perceptions of CV Risk and Statin Drugs and Racial Differences in Statin Use  @username @username","CONCLUSIONS AND RELEVANCE African American individuals were less likely to receive guideline-recommended statin therapy. Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention. Part of the explanation for this increased risk may be undertreatment of African American peoples for primary prevention.","[1.0, 4.0, 1.0, 3.0, 4.0]",Medicine,train,2.0,tweets,1006928867200663555
10.1186/1472-6920-12-82,Medicine_tweet_298,Gender Differences in Medical Students' Motives &amp; Career Choice ,"However, the significance of gender influence, stating the higher aspirations of women for general practice is not very strong (see table 4, Model 1: p = 0.046).",Gender Differences in Medical Students' Motives &amp; Career Choice ,"The finding that men aspire more to surgery specialties and women prefer more often general practice and nonsurgery specialties is consistent with previous research . However, the significance of gender influence, stating the higher aspirations of women for general practice is not very strong (see table 4, Model 1: p = 0.046). In separate analyses of different stages of education this gender influence even disappeared.","[4.0, 3.0, 3.0, 4.0, 4.0]",Medicine,train,3.6,tweets,241974413065584640
10.1016/j.neuron.2017.09.032,Medicine_tweet_299,"Brain synchrony in implicit vs explicit learning #neuroscience 
 ","In Figure 7A , we found that theta synchrony dropped both early (LM1, b = À0.28891, p = 0.027735, two-sided t test) and late (LM1, b = À0.27005, p = 0.015615).","Brain synchrony in implicit vs explicit learning #neuroscience 
 ","This was the case. In Figure 7A , we found that theta synchrony dropped both early (LM1, b = À0.28891, p = 0.027735, two-sided t test) and late (LM1, b = À0.27005, p = 0.015615). In other words, we did not see any difference in the change in theta synchrony before and after learning, like we did for alpha-2/beta-1.","[3.0, 1.0, 2.0, 4.0]",Medicine,train,2.5,tweets,918367395265351680
10.1377/hlthaff.2018.05101,Medicine_tweet_32,"New @username study suggests that state efforts to remove barriers to using #telehealth might not be sufficient for increasing use, and new incentives for providers and consumers to adopt and use telehealth may be needed.  @username",Policies that incentivize providers and health systems to use telehealth could be an important way to increase access to care for underserved populations.,"New @username study suggests that state efforts to remove barriers to using #telehealth might not be sufficient for increasing use, and new incentives for providers and consumers to adopt and use telehealth may be needed.  @username","Making telehealth easy to use is important but might not be enough to make providers or health systems invest the time, energy, and money needed to begin offering the service or expand its use. Policies that incentivize providers and health systems to use telehealth could be an important way to increase access to care for underserved populations. For example, offering financial incentives for providers to adopt telehealth may lead to increased usage, as payment incentives led to the increased adoption and use of electronic health records and patient-centered medical home status in safety-net clinics.","[1.0, 3.0, 5.0]",Medicine,train,5.0,tweets,1069710580695609344
10.1001/jamapsychiatry.2015.0500,Medicine_tweet_33,Antipsychotic use increased from 2006 to 2010 for adolescents and young adults in the US  #percentagesthough...,"There were approximately 270 000 antipsychotic prescriptions dispensed to younger children, 2.14 million to older children, 2.80 million to adolescents, and 1.83 million to young adults nationwide in 2010.",Antipsychotic use increased from 2006 to 2010 for adolescents and young adults in the US  #percentagesthough...,"The age and sex composition of the IMS population that filled at least 1 prescription of any kind closely resembled the composition of the corresponding population from the nationally representative Medical Expenditure Panel Survey. There were approximately 270 000 antipsychotic prescriptions dispensed to younger children, 2.14 million to older children, 2.80 million to adolescents, and 1.83 million to young adults nationwide in 2010. Across the 4 age groups, almost all of the antipsychotic prescriptions (96.7%) were for secondgeneration medications.","[3.0, 4.0, 2.0, 4.0]",Medicine,train,3.25,tweets,616296471634255872
10.1186/s12887-019-1528-1,Medicine_tweet_35,"Academic performance, executive function scores are positively correlated w/ age, Vitamin E levels, total antioxidant capacity, physical activity, negatively correlated w/ BMI (open access)



#nutrition #cardio #hiit #exercise #fitness #fit #muscle #lift","The academic performance and executive function scores were found to be positively correlated with age, gender, α-and γ-tocopherol, TAC activity, and PA score; and negatively correlated with BMI.","Academic performance, executive function scores are positively correlated w/ age, Vitamin E levels, total antioxidant capacity, physical activity, negatively correlated w/ BMI (open access)



#nutrition #cardio #hiit #exercise #fitness #fit #muscle #lift","Groups of adolescents who were moderately of highly active were found to have significantly higher levels of vitamin E, TAC activity, LTPA, and academic performance compared with mildly active participants. The academic performance and executive function scores were found to be positively correlated with age, gender, α-and γ-tocopherol, TAC activity, and PA score; and negatively correlated with BMI. Vitamin E levels and TAC activity could be used as indicators for improving executive function, PA and academic performance among students.","[5.0, 5.0, 3.0, 4.0]",Medicine,train,4.25,tweets,1130400928534806528
10.1001/jama.2014.15690,Medicine_tweet_36,Low-dose #aspirin and #CV events in #Japanese pts 60 yrs or older w atherosclerotic risk factors  #AHA14,"Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors.",Low-dose #aspirin and #CV events in #Japanese pts 60 yrs or older w atherosclerotic risk factors  #AHA14,"Reduction in the incidence of colorectal cancer may influence the overall benefit-risk profile of aspirin. Further analyses of the JPPP study data are planned, including analysis of deaths associated with cancers, to allow more precise identification of the patients for whom aspirin treatment may be most beneficial. Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors.","[2.0, 4.0, 4.0, 3.0, 4.0]",Medicine,train,3.4,tweets,534390530533515264
10.1136/bmj.j5644,Medicine_tweet_37,"A healthy diet seems to most benefit people with a genetic predisposition to #obesity
 @username #OA ","Moreover, the beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity.","A healthy diet seems to most benefit people with a genetic predisposition to #obesity
 @username #OA ","These data indicate that improving adherence to healthy dietary patterns could attenuate the genetic association with weight gain. Moreover, the beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity. Weights reported in questionnaires and measured by technicians were highly correlated (r=0.97 in both studies) in a validation subsample.","[4.0, 4.0, 5.0, 5.0, 5.0]",Medicine,train,4.6,tweets,951260235104047104
10.1098/rsos.172398,Medicine_tweet_38,The #behaviour of overweight #dogs shows similarity with #personality traits of overweight humans [BIOLOGY (WHOLE ORGANISM)]  BLet @username,"These results are very similar to those expected from the parallel models that exist between certain personality traits and being overweight in humans, suggesting that dogs are indeed a promising model for experimentally investigating obesity in humans.",The #behaviour of overweight #dogs shows similarity with #personality traits of overweight humans [BIOLOGY (WHOLE ORGANISM)]  BLet @username,"Our results also confirm that overweight dogs, as opposed to normal weight dogs, tried to maximize food intake from the higher quality food and hesitated to do the task when the food reward was uncertain. These results are very similar to those expected from the parallel models that exist between certain personality traits and being overweight in humans, suggesting that dogs are indeed a promising model for experimentally investigating obesity in humans. Dogs, due to their shared living environment with humans, may provide a beneficial model to study the causes and consequences of obesity.","[5.0, 4.0, 5.0, 5.0, 5.0]",Medicine,train,4.8,tweets,1004296558983036928
10.1001/jama.2015.1693,Medicine_tweet_39,Balloon-Expandable Stent vs Medical Therapy for Intracranial Stenosis ,These findings do not support the use of a balloon-expandable stent for patients with symptomatic intracranial arterial stenosis.,Balloon-Expandable Stent vs Medical Therapy for Intracranial Stenosis ,"Worsening of baseline disability score (modified Rankin Scale) occurred in more patients in the stent group (14/58; 24.1% [95% CI, 13.9%-37.2%]) vs the medical group (6/53; 11.3% [95% CI,.0%]) (P = .09).The EuroQol-5D showed no difference in any of the 5 dimensions between groups at 12-month follow-up. These findings do not support the use of a balloon-expandable stent for patients with symptomatic intracranial arterial stenosis. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00816166.","[3.0, 3.0, 1.0, 2.0, 2.0]",Medicine,train,2.2,tweets,580401347905871872
10.1007/s40264-014-0155-x,Medicine_tweet_4,Patients reporting AEs on TW showed sophistication - role in pharmacovigilance not established:  #hcsm #pharmacy,Conclusion Patients reporting AEs on Twitter showed a range of sophistication when describing their experience.,Patients reporting AEs on TW showed sophistication - role in pharmacovigilance not established:  #hcsm #pharmacy,"Similar overall distribution profiles were observed, with Spearman rank correlation rho of 0.75 (p \ 0.0001) between Proto-AEs reported in Twitter and FAERS by SOC. Conclusion Patients reporting AEs on Twitter showed a range of sophistication when describing their experience. Additional work is needed to improve data acquisition and automation.","[5.0, 3.0, 2.0, 3.0]",Medicine,train,3.25,tweets,461596772389756929
10.1001/jamasurg.2018.0672,Medicine_tweet_40,Poorer postoperative recovery in patients with lower functional health literacy! ,Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery.,Poorer postoperative recovery in patients with lower functional health literacy! ,"CONCLUSIONS AND RELEVANCE Inadequate FHL in patients undergoing day surgery was associated with poorer postoperative recovery and a lower health-related quality of life. Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery. 6 Considering this, the association between FHL and postoperative recovery in patients undergoing day surgery needs to be assessed.","[4.0, 3.0, 4.0, 4.0, 4.0]",Medicine,train,3.8,tweets,989287935248912384
10.1016/j.jpain.2017.11.005,Medicine_tweet_41,"#acupuncture has a clinically relevant effect on #chronicpain that persists over time.

The effect of acupuncture cannot be explained only by placebo effects. ",Another novel finding is the higher than average effects of acupuncture on upper body musculoskeletal pain.,"#acupuncture has a clinically relevant effect on #chronicpain that persists over time.

The effect of acupuncture cannot be explained only by placebo effects. ","In some cases, heterogeneity was also driven by a set of outlying trials with large effect sizes. Another novel finding is the higher than average effects of acupuncture on upper body musculoskeletal pain. We now have sufficient data to conduct a meta-analysis for neck pain and for shoulder pain, even after exclusion of outlying trials.","[4.0, 2.0, 3.0, 4.0]",Medicine,train,3.25,tweets,990283938320076801
10.1016/j.psyneuen.2016.08.027,Medicine_tweet_42,Can women's cortisol levels predict their likelihood of getting #pregnant when having #IVF?  ,"Despite these potential limitations, the present study extends the available evidence for the role of cortisol on clinical pregnancy in IVF patients and provides the first evidence that elevated chronic cortisol levels are associated with a reduced likelihood of pregnancy.",Can women's cortisol levels predict their likelihood of getting #pregnant when having #IVF?  ,"It is also not clear how generalizable our results are to women trying to conceive naturally; also our findings extend only to clinical pregnancy. Despite these potential limitations, the present study extends the available evidence for the role of cortisol on clinical pregnancy in IVF patients and provides the first evidence that elevated chronic cortisol levels are associated with a reduced likelihood of pregnancy. Thus, further research is needed to not only corroborate these findings but also identify the pathways.","[4.0, 5.0, 3.0, 4.0]",Medicine,train,4.0,tweets,803233989997699072
10.1038/s41467-019-09961-w,Medicine_tweet_43,"Thrilled that our new paper is out @username:  In this work with Dan Schacter and @username, we show that episodic simulations can form real-life attitudes and how this is supported by affective representations in the vmPFC. 1/5 ","By this process, episodic simulations modify attitudes toward the very elements that the simulations had been based on, thus influencing how we evaluate our real-life environment.","Thrilled that our new paper is out @username:  In this work with Dan Schacter and @username, we show that episodic simulations can form real-life attitudes and how this is supported by affective representations in the vmPFC. 1/5 ","Such evaluative conditioning forms attitudes by changing the liking of the CS to align with the valence of the UCS . By this process, episodic simulations modify attitudes toward the very elements that the simulations had been based on, thus influencing how we evaluate our real-life environment. Our hypothesis assigns a key role to the vmPFC in mediating such presumed attitude change.","[4.0, 5.0, 4.0, 5.0, 5.0]",Medicine,train,4.6,tweets,1129381200391540737
10.1186/s12940-019-0488-0,Medicine_tweet_44,"There are 72, 17, and 11 pesticides approved for outdoor agricultural applications in the USA that are banned or in the process of complete phase out in the EU, Brazil, and China, respectively.  ","More than 10% of total pesticide use in the USA in 2016 was from pesticide ingredients either banned, not approved or of unknown status in all three agricultural nations (Table 1 and Additional file 5:  Table S137 ).","There are 72, 17, and 11 pesticides approved for outdoor agricultural applications in the USA that are banned or in the process of complete phase out in the EU, Brazil, and China, respectively.  ","Of the 1.2 billion pounds of pesticides used in USA agriculture in 2016, roughly 322 million pounds were of pesticides banned in the EU, 40 million were of pesticides banned in China and nearly 26 million were of pesticides banned in Brazil (Table 1 and Additional file  5: Tables S131-S133 ). More than 10% of total pesticide use in the USA in 2016 was from pesticide ingredients either banned, not approved or of unknown status in all three agricultural nations (Table 1 and Additional file 5:  Table S137 ). From 1992 to 2016, the trends in use of the 13 pesticides that are banned in at least two other places and used in the USA varied by pesticide (Fig.","[3.0, 3.0, 4.0, 3.0, 4.0]",Medicine,train,3.4,tweets,1136804388507463680
10.1038/s41598-018-29793-w,Medicine_tweet_45,"Nasal microbiota clusters associate with inflammatory response, viral load... - Lehtinen MJ et al. -  #microbiome","Thus, microbiota at the time of infection may influence subsequent rhinovirus viral load.","Nasal microbiota clusters associate with inflammatory response, viral load... - Lehtinen MJ et al. -  #microbiome","Subjects with Ps/Mix cluster had significantly lower viral load than those subjects with Mor or Staph predominant microbiota types (Fig. Thus, microbiota at the time of infection may influence subsequent rhinovirus viral load. The results also suggest that high inflammatory response does not lead to low viral load as the subjects with Ps/Mix and Mor clusters had both relatively high inflammatory cytokine response and only Ps/Mix cluster had low viral load.","[2.0, 3.0, 4.0, 4.0]",Medicine,train,3.25,tweets,1024582940532133889
10.1038/srep01456,Medicine_tweet_47,Bed bugs evolved unique adaptive strategy to resist pyrethroid ...: Recent advances in genomic and post-genomi... ,Our data showed that multiple mechanisms involved in pyrethroid resistance is not only a phenomenon occurring in laboratory bed bug strains but also is widespread in naturally occurring bed bug populations (Figs.,Bed bugs evolved unique adaptive strategy to resist pyrethroid ...: Recent advances in genomic and post-genomi... ,"3D) is also interesting and further research is required to understand functional significance of this observation. Our data showed that multiple mechanisms involved in pyrethroid resistance is not only a phenomenon occurring in laboratory bed bug strains but also is widespread in naturally occurring bed bug populations (Figs. Inactivation of four P450 target genes significantly enhanced the susceptibility of resistant bed bugs to pyrethroid insecticide, which further confirmed the involvement of P450-mediated metabolic detoxification in pyrethroid resistance of bed bugs.","[3.0, 5.0, 3.0, 5.0]",Medicine,train,4.0,tweets,312697337266991106
10.1001/jama.2018.20578,Medicine_tweet_48,"In this case, I'm not really sure that pooling 164 225 heterogenous patients really does help... I'm not convinced. #aspirin for primary prevention is still dead to me. @username @username ","In this meta-analysis of 13 trials enrolling 164 225 participants without cardiovascular disease, aspirin use was associated with reductions in the composite cardiovascular outcome consisting of cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke.","In this case, I'm not really sure that pooling 164 225 heterogenous patients really does help... I'm not convinced. #aspirin for primary prevention is still dead to me. @username @username ","Aspirin use was associated with increased risk of major bleeding (HR, In this meta-analysis of 13 trials enrolling 164 225 participants without cardiovascular disease, aspirin use was associated with reductions in the composite cardiovascular outcome consisting of cardiovascular mortality, nonfatal myocardial infarction, and nonfatal stroke. However, aspirin use was associated with an increased risk of major bleeding, intracranial bleeding, and major gastrointestinal bleeding with comparable absolute risk estimates.","[3.0, 2.0, 3.0, 1.0, 3.0]",Medicine,train,2.4,tweets,1087857553655005185
10.1073/pnas.1504869112,Medicine_tweet_49,Lianas reduce tropical forests' #carbon accumulation and storage   #TheTarzanEffect,"This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets.",Lianas reduce tropical forests' #carbon accumulation and storage   #TheTarzanEffect,"By impacting on tree growth and survival, lianas impact the carbon balance of these forests. This study is the first direct demonstration of liana effects at the ecosystem scale and illustrates the important role of lianas in tropical forests, particularly with respect to carbon budgets. Lianas are increasing in biomass and productivity throughout the tropics, and thus our findings have even greater relevance in terms of the fate of the tropical carbon balance, as well as for global atmospheric CO 2 levels, in a changing climate.","[4.0, 5.0, 2.0, 4.0, 4.0]",Medicine,train,3.8,tweets,658602471737069568
10.1038/s41598-018-29793-w,Medicine_tweet_5,"Characterizing the healthy nasal #microbiome discovers groups of microbes that differently modulate the inflammatory response and relate differently to symptom severity in rhinoviral colds. #commoncold #immuneresponse
","The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection.","Characterizing the healthy nasal #microbiome discovers groups of microbes that differently modulate the inflammatory response and relate differently to symptom severity in rhinoviral colds. #commoncold #immuneresponse
","We found that nasal microbiotas of healthy adults in our study cohort grouped into six distinct clusters Staph, Cor/All, Mor, Hae, Ps/Mix, and Mixed, based on the predominant bacterial genera in the nasal microflora. The microbiota clusters appear to associate with different inflammatory response, viral titer, and symptom severity profiles in rhinovirus infection. Our study is aligned with the previous findings suggesting that the microbiota in the nose has seasonal variation.","[5.0, 5.0, 3.0, 3.0]",Medicine,train,4.0,tweets,1093938835413553152
10.1073/pnas.1504869112,Medicine_tweet_50,"Lianas reduce net carbon storage in #tropicalforests by 75%!  Lianas on the rise, implications for the land C sink ","Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests.","Lianas reduce net carbon storage in #tropicalforests by 75%!  Lianas on the rise, implications for the land C sink ","Longer-term data are needed to assess whether this initial difference in carbon sink potential persists over time. Notwithstanding, our results indicate that, due to their unique attributes, lianas have the potential to severely reduce both the carbon sink potential and long-term carbon storage capacity of tropical forests. While the strength of the liana effect will vary with the density and biomass of lianas, the increase in liana density, biomass, and productivity reported in many neotropical forests (9, 10, 23) may be partially responsible for the longterm decline in the Amazonian carbon sink , which in turn contributes to increasing atmospheric carbon dioxide levels and accelerated climate change.","[4.0, 4.0, 4.0, 4.0]",Medicine,train,4.0,tweets,657953352681172996
10.1126/sciadv.aau2477,Medicine_tweet_51,"Our new JPL-NASA study out in Science Adv., uses GPS to track the weight of #HurricaneHarvey's stormwater. We found Houston was not only pushed down 2 cm by Harvey's stormwater, but then sprung back up over ~5 weeks, giving clues to water loss over time.  ","Inversion of these data shows that a third of Harvey's total stormwater was captured on land (25.7 ± .0 km ), indicating that the rest drained rapidly into the ocean at a rate of 8.2 km","Our new JPL-NASA study out in Science Adv., uses GPS to track the weight of #HurricaneHarvey's stormwater. We found Houston was not only pushed down 2 cm by Harvey's stormwater, but then sprung back up over ~5 weeks, giving clues to water loss over time.  ","Water left in Harvey's wake should cause elastic loading and subsidence of Earth's crust, and uplift as it drains into the ocean and evaporates. Inversion of these data shows that a third of Harvey's total stormwater was captured on land (25.7 ± .0 km ), indicating that the rest drained rapidly into the ocean at a rate of 8.2 km Over a period of 7 days, Harvey produced record-breaking rainfall, with 1.54 m of precipitation measured southeast of Houston, causing extensive flooding and $125 billion in damage, an amount second only to Hurricane Katrina .","[3.0, 3.0, 3.0, 2.0, 3.0]",Medicine,train,2.8,tweets,1042474835681533952
10.1038/s41390-018-0199-1,Medicine_tweet_52,"Neonatal regulatory behavior problems are predicted by maternal early pregnancy overweight &amp; obesity

A number of 3117 women of the PREDO Study filled in a questionnaire on regulatory behavior problems at the child’s mean age of 16.9 days 

",Our findings suggest that prevention of overweight/obesity in women of childbearing age will benefit the offspring by reducing the burden of regulatory problems in infancy and preventing their long-term neurodevelopmental consequences.,"Neonatal regulatory behavior problems are predicted by maternal early pregnancy overweight &amp; obesity

A number of 3117 women of the PREDO Study filled in a questionnaire on regulatory behavior problems at the child’s mean age of 16.9 days 

","In sum, our study showed that infants of overweight/obese mothers displayed higher levels of regulatory behavior problems and were more likely to display problems on multiple areas of behavioral self-regulation. Regulatory behavior problems partially mediated the effects of maternal overweight/obesity on childhood developmental milestones. Our findings suggest that prevention of overweight/obesity in women of childbearing age will benefit the offspring by reducing the burden of regulatory problems in infancy and preventing their long-term neurodevelopmental consequences.","[4.0, 5.0, 4.0, 4.0, 4.0]",Medicine,train,4.2,tweets,1053292082104881152
10.1177/0141076815593403,Medicine_tweet_53,stat. meth in Swedish trials has led to overestimat of risk reduction in breast cancer death due to mammo screening. ,"Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death also applied to cancer cases diagnosed when screening (or absence of screening) was the same in both screening and control groups.",stat. meth in Swedish trials has led to overestimat of risk reduction in breast cancer death due to mammo screening. ,"The compensation argument invoked by Swedish trial investigators 6, is thus not tenable. Our re-calculations of Swedish trial revealed that risks of breast cancer death were similar for cancers found during the intervention and the post-intervention periods, indicating that reductions in the risk of breast cancer death also applied to cancer cases diagnosed when screening (or absence of screening) was the same in both screening and control groups. Such result is compatible with an effect of being allocated to the screening or to the control group on the risk of breast cancer death (allocation effect), but not with an effect of mammography screening (screening effect) on that risk.","[3.0, 3.0, 3.0, 5.0]",Medicine,train,3.5,tweets,618657906418950144
10.1093/geronb/gbv101,Medicine_tweet_54,"The secret of staying young

I personally thrive on stress. And if necessary will create situations that encourage it.

 The Combined Effects of Daily Stressors and Major Life Events on Daily Subjective... ","Taken together, we predict that when a significant relationship exists between daily stressors and subjective age, it will be mediated by positive affect, personal control, and negative affect.","The secret of staying young

I personally thrive on stress. And if necessary will create situations that encourage it.

 The Combined Effects of Daily Stressors and Major Life Events on Daily Subjective... ","We further suspect that on a daily level, individuals' subjective age may be influenced by negative affect. Taken together, we predict that when a significant relationship exists between daily stressors and subjective age, it will be mediated by positive affect, personal control, and negative affect. Nearly all participants reported their employment status as retired (n = 41).","[3.0, 3.0, 1.0]",Medicine,train,2.333333333333333,tweets,1014776707755270144
10.1001/jama.2013.277165,Medicine_tweet_56,#Anticoagulation With #Otamixaban and Ischemic Events in NSTE-ACS #esc2013 ,Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy.,#Anticoagulation With #Otamixaban and Ischemic Events in NSTE-ACS #esc2013 ,"Other regimens might have offered a different benefit-risk profile, 19, 26, 27 but because otamixaban did not display superior efficacy and did show worse safety, this point is moot. Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy. These findings do not support the use of otamixaban for patients with NSTE-ACS undergoing planned early percutaneous coronary intervention.","[2.0, 3.0, 4.0, 3.0, 3.0]",Medicine,train,3.0,tweets,374147717842206721
10.1038/s41598-018-25573-8,Medicine_tweet_57,A customised #cancertreatment replicating ovarian #tumours inside chicken eggs ,These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.,A customised #cancertreatment replicating ovarian #tumours inside chicken eggs ,"Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer. Tumor recurrence and metastasis are primarily responsible for the 70% five-year mortality of advanced EOC.","[1.0, 3.0, 3.0, 3.0]",Medicine,train,2.5,tweets,1006702719170744321
10.1001/jama.2018.14619,Medicine_tweet_59,"In our latest @username funded study in @username, people with severe obesity &amp; diabetes who had bariatric surgery were associated with 40% lower 5-year risk of heart attack and stroke than matched people who got usual medical care  ",Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events.,"In our latest @username funded study in @username, people with severe obesity &amp; diabetes who had bariatric surgery were associated with 40% lower 5-year risk of heart attack and stroke than matched people who got usual medical care  ","The findings require confirmation in randomized clinical trials. Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events. [5] [6] [7] [8] [9] In comparison, patients who have bariatric surgery have better glycemic control and greater macrovascular risk factor reduction than those who get both intensive lifestyle and medical treatment combined.","[4.0, 5.0, 4.0, 3.0, 2.0]",Medicine,train,3.6,tweets,1052217491076931584
10.1038/s41467-018-08278-4,Medicine_tweet_6,"Ken Muneoka and colleagues @username find that BMP9 treatment promotes joint regeneration from digit amputation wounds.

",We show here that Bmp9 is transiently expressed during digit joint cavitation and that BMP9 treatment stimulates joint regeneration.,"Ken Muneoka and colleagues @username find that BMP9 treatment promotes joint regeneration from digit amputation wounds.

","Unlike other BMP family members, BMP9 is not effected by BMP antagonists such as Noggin 12 which suppresses BMP signaling and is necessary for joint morphogenesis . We show here that Bmp9 is transiently expressed during digit joint cavitation and that BMP9 treatment stimulates joint regeneration. During angiogenesis, BMP9 acts in a contextdependent manner, inhibiting neovascularization in a model of age-related macular degeneration , while stimulating angiogenesis associated with induced osteogenesis .","[4.0, 5.0, 1.0, 4.0, 5.0]",Medicine,train,5.0,tweets,1095638718826926080
10.1111/jgs.15671,Medicine_tweet_60,"Quality of end of life care in U.S. hospitals is poor. Improving nurse work environments may be a key intervention to improve EOL care quality. 
@username @username   ",The best predictor of poor quality was the nurse practice environment.,"Quality of end of life care in U.S. hospitals is poor. Improving nurse work environments may be a key intervention to improve EOL care quality. 
@username @username   ",The best predictor of poor quality was the nurse practice environment. Nurses in the best environments were 55% less likely than nurses in poor environments to rate their hospital's overall end-oflife care quality unfavorably (odds ratio = 0.45; 95% confidence interval = 0.39-0.52; P < .001). CONCLUSION: Quality of end-of-life care in US hospitals is imperfect and is significantly worse in hospitals with poor nurse practice environments than in hospitals with the best environments.,"[5.0, 4.0, 4.0, 4.0, 1.0]",Medicine,train,5.0,tweets,1069599220720697349
10.1016/j.ejca.2017.11.022,Medicine_tweet_61,Consumption of #processed #meat may increase risk of #breast #cancer ,"Among participants who had the highest intake of processed meat, the incidence of breast cancer was 2.55 per 1,000 population per annum among those with low cooked vegetable intake and 2.35 per 1,000 per annum among those with high intake.",Consumption of #processed #meat may increase risk of #breast #cancer ,"This was due to the absolute risk already being higher in this sub-group; among participants who ate no processed meat, the incidence of breast cancer was 2.46 per 1,000 population per annum among those with low intake of cooked vegetables compared with only 2.01 per 1,000 per annum among those with high vegetable intake. Among participants who had the highest intake of processed meat, the incidence of breast cancer was 2.55 per 1,000 population per annum among those with low cooked vegetable intake and 2.35 per 1,000 per annum among those with high intake. There was no significant interaction with menopausal status.","[4.0, 4.0, 3.0, 4.0]",Medicine,train,3.75,tweets,945569755339124737
10.1080/00224499.2013.843148,Medicine_tweet_62,"Of 600 12-15yo, 54% hadn't discussed any sexual health issues w/ dating partners, 29% w/ parents, 25% w/ best friends ","Among this sexually active sample, 20 adolescents (38%) reported they had not used condoms every time they had sex in the past year, and 9 youth (17%) reported they had not discussed any sexual health topics with their dating partners.","Of 600 12-15yo, 54% hadn't discussed any sexual health issues w/ dating partners, 29% w/ parents, 25% w/ best friends ","Of the 603 7th and 8th graders that we sampled, 53 (8.8%; 29 girls, 24 boys) had engaged in sexual intercourse in the past year and 23 (3.8%; 12 girls, 11 boys) had had sex with two or more partners. Among this sexually active sample, 20 adolescents (38%) reported they had not used condoms every time they had sex in the past year, and 9 youth (17%) reported they had not discussed any sexual health topics with their dating partners. In addition, when asked about use of protection at first intercourse, 29 youth (55%) reported they had used a condom, and 8 of these adolescents (15%) indicated they had used both condoms and birth control pills the first time they had sex.","[3.0, 4.0, 3.0, 3.0, 4.0]",Medicine,train,3.4,tweets,487250531019423744
10.1186/s12889-017-4672-2,Medicine_tweet_63,Using your mobile phone during #pregnancy is unlikely to cause adverse neurodevelopmental effects  #bmcpublichealth,"Our unique findings do not support the hypothesis of adverse effects on children's language, communication and motor skills due to maternal cell phone use during gestation.",Using your mobile phone during #pregnancy is unlikely to cause adverse neurodevelopmental effects  #bmcpublichealth,"These associations were confirmed by dose-response trends, even after excluding non-users. Our unique findings do not support the hypothesis of adverse effects on children's language, communication and motor skills due to maternal cell phone use during gestation. Nevertheless, in the Spanish study cell phone users had children who scored higher in the Bayley mental scale and in the Danish study there was a trend for lower risk for cognitive/language delay at 6 months [ .","[5.0, 5.0, 5.0, 5.0, 5.0]",Medicine,train,5.0,tweets,904972366790479876
10.1001/jamainternmed.2013.6536,Medicine_tweet_64,MT @username: Replacing carbs  &amp; animal fat with veg fat linked to lower risk of lethal prostate cancer. JAMA ,"In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality.",MT @username: Replacing carbs  &amp; animal fat with veg fat linked to lower risk of lethal prostate cancer. JAMA ,"Post-diagnostic intakes of mayonnaise and margarine were not associated with risk of lethal prostate cancer or all-cause mortality. In this prospective analysis, vegetable fat intake after diagnosis was associated with a lower risk of lethal prostate cancer and all-cause mortality. Among 525 Swedish men, marine fatty acids were associated with lower risk of prostate cancer death (events: 222; HR Q4 v. Q1: 0.5; 5% CI: 0.40, 0.87) and, among the men diagnosed with localized disease (46 events), myristic acid and shortchain saturated fatty acids were associated with higher risk of prostate cancer death (HR Q4 v Q1: 2.3; 5% CI: 1.06, 5.38 and HR Q4 v. Q1: 2.88; 5% CI: 1.24, 6.67, respectively).","[5.0, 3.0, 5.0, 5.0]",Medicine,train,4.5,tweets,344467954030739456
10.1016/j.bodyim.2016.09.005,Medicine_tweet_65,"Do you think Barbie has an effect on our body image?
  
In this recent study, the impact of different types of... ","Continued exposure to Barbie in early childhood may lead girls to not only adopt a thin ideal but also, in combination with a variety of other thin-ideal transmitters, may prime them to more readily accept future thin-ideal promoting messages.","Do you think Barbie has an effect on our body image?
  
In this recent study, the impact of different types of... ","However, it is still possible that different types of exposure could have differential cumulative impact over time, which would only become apparent in a longitudinal study. Continued exposure to Barbie in early childhood may lead girls to not only adopt a thin ideal but also, in combination with a variety of other thin-ideal transmitters, may prime them to more readily accept future thin-ideal promoting messages. Future research is necessary to establish this link.","[3.0, 3.0, 4.0, 4.0]",Medicine,train,3.5,tweets,788087593191677952
10.1377/hlthaff.2018.05101,Medicine_tweet_66,"Excited to have our new @username study out in @username showing use of video visits for #telehealth has increased dramatically in the U.S. (from 6.6% in 2013 to 21.6% in 2016); however, use lowest for Medicaid, low income and rural populations. ",The use of telehealth increased dramatically in the period 2013-16 across all population groups.,"Excited to have our new @username study out in @username showing use of video visits for #telehealth has increased dramatically in the U.S. (from 6.6% in 2013 to 21.6% in 2016); however, use lowest for Medicaid, low income and rural populations. ","[31] Demonstrating the role that telehealth can play in achieving the Triple Aim of improving quality and health outcomes while lowering the cost of care could prove to be a powerful incentive for increased uptake. The use of telehealth increased dramatically in the period 2013-16 across all population groups. While we found evidence that populations with limited mobility (such as Medicare beneficiaries younger than age sixty-five and people with selfreported physical or mental health concerns that limit their activities) were among the highest users, key underserved populations (including Medicaid, low-income, and rural populations) had significantly lower use of telehealth.","[4.0, 5.0, 1.0, 4.0, 5.0]",Medicine,train,5.0,tweets,1069708111756193792
10.1001/jamaneurol.2017.4618,Medicine_tweet_67,Acute Brain Lesions Associated With DNS in Carbon Monoxide Poisoning ,Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae.,Acute Brain Lesions Associated With DNS in Carbon Monoxide Poisoning ,The presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae. Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae. Documenting acute lesions that can potentially indicate the subsequent development of DNS could give clinicians and researchers useful information for understanding the pathophysiology of DNS and targeting prevention.,"[4.0, 2.0, 3.0, 4.0, 4.0]",Medicine,train,3.4,tweets,958173693795971073
10.1001/jamapediatrics.2018.0302,Medicine_tweet_68,#Vitamin D supplementation during #pregnancy may reduce the risk for underweight babies and fetal or infant mortality. ,"Late vitamin D supplementation (initiation at ≥20 weeks' gestation) improved birth weight, but early supplementation (initiation at <20 weeks' gestation) did not.",#Vitamin D supplementation during #pregnancy may reduce the risk for underweight babies and fetal or infant mortality. ,"We found that maternal vitamin D supplementation timing, dose, and administration method did not affect cord blood vitamin D concentration. Late vitamin D supplementation (initiation at ≥20 weeks' gestation) improved birth weight, but early supplementation (initiation at <20 weeks' gestation) did not. Most importantly, we found that the lower dose of vitamin D supplementation (≤2000 IU/d) reduced the risk of fetal or neonatal mortality and SGA, but the higher dose (>2000 IU/d) did not.","[4.0, 2.0, 5.0, 2.0]",Medicine,train,4.0,tweets,1001559206733012993
10.1186/gb-2013-14-7-r73,Medicine_tweet_70,vlincRNA (50kb - 700kb long) in pluripotency and cancer - Genome Biol  h/t @username,Our results suggest that gene regulation via vlincRNAs and macroRNAs could be a general theme in human cells.,vlincRNA (50kb - 700kb long) in pluripotency and cancer - Genome Biol  h/t @username,"These properties make vlincRNA regions similar to macroRNAs which were previously associated only with the regulation of imprinting . Our results suggest that gene regulation via vlincRNAs and macroRNAs could be a general theme in human cells. In this respect, the abundance of these transcripts relative to annotated coding mRNAs is noteworthy.","[2.0, 4.0, 1.0, 3.0, 3.0]",Medicine,train,2.6,tweets,365501527806316546
10.1007/s00125-015-3781-7,Medicine_tweet_71,Major fall in diabetes-related amputations since the 1990s  #Diabetologia @username @username,"The total number of amputations amounted to 2,832, of which 1,285 were among individuals with diabetes and 1,547 among individuals without diabetes.",Major fall in diabetes-related amputations since the 1990s  #Diabetologia @username @username,"The different curves thus start at age of diagnosis and duration of diabetes equal to 0, so it can be seen that the initial high rates decrease in about 1 year and the major effect is then age related. The total number of amputations amounted to 2,832, of which 1,285 were among individuals with diabetes and 1,547 among individuals without diabetes. We found a substantial reduction by calendar time in BAA rates among patients with diabetes of almost 10% per year.","[3.0, 2.0, 3.0, 3.0]",Medicine,train,2.75,tweets,668700522493313024
10.1002/ijc.31746,Medicine_tweet_73,"Today's #MastermindFind: Sequencing and analysis of ANO7 reveals Caucasian SNPs associated with increased risk of prostate cancer, or decreased patient survival. #ProstateCancer #genetics


 ","In our study, higher ANO7 mRNA expression strongly correlated with poor overall survival in PrCa patients.","Today's #MastermindFind: Sequencing and analysis of ANO7 reveals Caucasian SNPs associated with increased risk of prostate cancer, or decreased patient survival. #ProstateCancer #genetics


 ","on the other hand, reported high individual variability of ANO expression between individual samples, both in terms of absolute expression levels and of expression level ratios between matched normal and tumorous prostate. In our study, higher ANO7 mRNA expression strongly correlated with poor overall survival in PrCa patients. Multivariate analysis compared high and low ANO7 expression and showed an even stronger negative survival effect than the model with the three selected SNPs, indicating that there might be additional variants that regulate expression.","[4.0, 4.0, 5.0, 5.0, 4.0]",Medicine,train,4.4,tweets,1044200031992139776
10.1001/jamapediatrics.2013.78,Medicine_tweet_74,Parent conversations with children about their weight associated with disordered eating behaviours ,"This study builds on recent research focusing on fathers and their role in adolescent eating disorders treatment 32, [41] [42] [43] and finds that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not.",Parent conversations with children about their weight associated with disordered eating behaviours ,"This approach may be particularly important for parents of overweight or obese adolescents. This study builds on recent research focusing on fathers and their role in adolescent eating disorders treatment 32, [41] [42] [43] and finds that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not. Thus, it may be important to educate fathers to avoid any form of weight-related conversations with their adolescents.","[3.0, 4.0, 4.0, 4.0, 4.0]",Medicine,train,3.8,tweets,349679298631835648
10.1186/1471-2431-13-162,Medicine_tweet_75,What are the FSA @username doing about the high levels of aluminium found in UK baby milk? ,We consider that the aluminium content of all infant formulas investigated herein is too high and especially so considering that these products constitute either all or a substantial proportion of an infant's diet in the first months of their lives.,What are the FSA @username doing about the high levels of aluminium found in UK baby milk? ,The concentration of aluminium in each of the 30 infant formulas is at least twice that which is recommended in the European Union for drinking water (50 μg/L) and in 14 of the milks it exceeds the maximum admissible level for drinking water of 200 μg/L . We consider that the aluminium content of all infant formulas investigated herein is too high and especially so considering that these products constitute either all or a substantial proportion of an infant's diet in the first months of their lives. Based upon the criteria for drinking water they are not fit for human consumption and they contravene article 5 of the Food Safety Act which states that 'infant formulas should not contain anything which might endanger the health of infants and young children' .,"[4.0, 2.0, 2.0, 5.0, 4.0]",Medicine,train,5.0,tweets,388456794898829313
10.1126/scitranslmed.aab1290,Medicine_tweet_76,Drug Delivers Estrogen Selectively to the Brain to Treat Neurological Disorders #SciTM  via @username @username,We reveal the therapeutic potential of DHED on estrogen deficiency-associated neurological disorders and psychiatric conditions without encountering adverse systemic actions that are typically seen with the direct use of estrogens.,Drug Delivers Estrogen Selectively to the Brain to Treat Neurological Disorders #SciTM  via @username @username,"Although this method provides increased selectivity in CNS delivery of the hormone, it still generates elevated levels of the hormone in the periphery with substantial uterotrophic side effects and sustained high circulating estrogen levels even after acute dosing . We reveal the therapeutic potential of DHED on estrogen deficiency-associated neurological disorders and psychiatric conditions without encountering adverse systemic actions that are typically seen with the direct use of estrogens. The reductive bioactivation of DHED to E 2 proceeds through hydride transfer from the coenzyme NADPH to the C1 position of the C1-C2 double bond of DHED's Aring that is conjugated to the 3-carbonyl group.","[4.0, 4.0, 4.0, 4.0, 4.0]",Medicine,train,4.0,tweets,623932971901435906
10.1001/jama.2013.285112,Medicine_tweet_79,Tobacco control responsible for 30% of the increase in life expectancy in US in past 50 years. ,"In women, life expectancy at age 40 years increased 5.4 years (from 37.4 to 42.7 years), but without tobacco control, it would have been projected to increase by only 3.8 years (from 37.3 to 41.2 years).",Tobacco control responsible for 30% of the increase in life expectancy in US in past 50 years. ,"Hence, 2.3 years (CR, 1.8-2.5) or 30% (CR, 23%-32%) of improved life expectancy for men is projected to be associated with tobacco control. In women, life expectancy at age 40 years increased 5.4 years (from 37.4 to 42.7 years), but without tobacco control, it would have been projected to increase by only 3.8 years (from 37.3 to 41.2 years). Tobacco control appears to be associated with 1.6 years (CR, 1.4-1.7) of the improvement in life expectancy for women or 29% (CR, 25%-32%) of the gain.","[3.0, 4.0, 4.0, 4.0, 4.0]",Medicine,train,3.8,tweets,421008651134844928
10.1186/s13293-018-0204-8,Medicine_tweet_8,"More attention needs to be dedicated to investigating the varied development, function, and biology in lower urinary tract between females and males on a cellular level, a new review paper explains. #sexdifferences ","This review serves to characterize the current understanding of biological sex differences between female and male lower urinary tracts, while identifying areas for future research.","More attention needs to be dedicated to investigating the varied development, function, and biology in lower urinary tract between females and males on a cellular level, a new review paper explains. #sexdifferences ","Recognizing that cell biology is not uniform, especially in the lower urinary tract of females and males, is crucial for providing context and relevance for diverse fields of biomedical investigation. This review serves to characterize the current understanding of biological sex differences between female and male lower urinary tracts, while identifying areas for future research. First, the differences in overall cell populations are discussed in the detrusor smooth muscle, urothelium, and trigone.","[4.0, 5.0, 4.0, 5.0, 3.0]",Medicine,train,4.2,tweets,1057993659721883648
10.1192/bjp.bp.111.101196,Medicine_tweet_80,Fascinating piece on ADHD in elderly people Discusses prevalence rates of #ADHD in older adults. ,Given the chronicity and impact of the ADHD one might have expected that older adults with ADHD experience impairments in these three areas.,Fascinating piece on ADHD in elderly people Discusses prevalence rates of #ADHD in older adults. ,"Another striking finding is that older adults with ADHD did not differ in living situation, level of education and income compared to older adults without ADHD. Given the chronicity and impact of the ADHD one might have expected that older adults with ADHD experience impairments in these three areas. There are several explanations for this finding.","[2.0, 2.0, 2.0, 2.0, 3.0]",Medicine,train,2.2,tweets,654074801280167936
10.1038/s41562-018-0366-8,Medicine_tweet_81,NEW RESEARCH finds that memory consolidation and reconsolidation share common behavioural and neurochemical mechanisms  From researchers at @username &amp; #UniversityofRegensburg ,The similarity in the time-course changes in the E/I ratio and behavioural performance between reconsolidation and consolidation is in accordance with the hypothesis that these two processes have similar or some common underlying mechanisms.,NEW RESEARCH finds that memory consolidation and reconsolidation share common behavioural and neurochemical mechanisms  From researchers at @username &amp; #UniversityofRegensburg ,"First, although it has been controversial whether reactivation and reconsolidation of skill learning occurs in humans, our results show that reactivation and reconsolidation indeed occur in humans with VPL, a type of procedural learning. The similarity in the time-course changes in the E/I ratio and behavioural performance between reconsolidation and consolidation is in accordance with the hypothesis that these two processes have similar or some common underlying mechanisms. Thus, the E/I ratio decreases from high after the end of training or reactivation to baseline levels 3.5 hour later, thereby reflecting that both consolidation and reconsolidation are associated with decreases in the degree of plasticity.","[5.0, 4.0, 5.0, 4.0]",Medicine,train,4.5,tweets,1016660830346244096
10.1073/pnas.1515528113,Medicine_tweet_83,On missing the opportunity to nearly eradicate cervical and #HPV-induced #cancer  @username ,"Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders.",On missing the opportunity to nearly eradicate cervical and #HPV-induced #cancer  @username ,"Because of the impact of herd immunity, any expansion in coverage will be much more effective in reducing cancer incidence and healthcare costs if targeted in those states with the lowest coverage. Because of interstate migration and the long duration between HPV infection and resultant cervical cancer, much of the benefit of vaccination will be realized beyond a state's borders. Therefore, both cervical cancer incidence and expenditure can be substantially reduced if the states coordinate policies to promote expansion of coverage, particularly for the new nonavalent vaccine.","[3.0, 3.0, 2.0, 1.0]",Medicine,train,2.25,tweets,722161035726049280
10.3945/an.111.000513,Medicine_tweet_85,Apples and their relationship to human health-#fructose from fruit different from added fructose-,"In men, the risk reduction was 19% in the group consuming >54 g compared to no apple intake .",Apples and their relationship to human health-#fructose from fruit different from added fructose-,"A group of Finnish women consuming >71 g of apple/d experienced a 43% reduction in coronary mortality compared to women who did not eat apples. In men, the risk reduction was 19% in the group consuming >54 g compared to no apple intake . These findings were consistent with prior data showing reduced coronary mortality in elderly Dutch men (65-84 y) who consumed apples (average 69 g/d) compared to men who had little or no apple intake .","[1.0, 2.0, 2.0, 4.0, 4.0]",Medicine,train,4.0,tweets,199840951517196289
10.1007/s10803-016-2729-1,Medicine_tweet_86,We need more police training about autism  Remember hearing Dennis Debbaudt talk about this ,"Further, 47% of police reported that they were 'fairly knowledgeable' about ASD.",We need more police training about autism  Remember hearing Dennis Debbaudt talk about this ,"More specifically, police respondents were largely satisfied (42%) with their dealings with the ASD community; with only 21% reporting dissatisfaction (37% gave a neutral response). Further, 47% of police reported that they were 'fairly knowledgeable' about ASD. However, the possibility of a discrepancy between police self-reported competence and professional conduct in practice cannot be discounted.","[2.0, 2.0, 3.0, 4.0, 3.0]",Medicine,train,2.8,tweets,697728625634897920
10.1016/j.cels.2017.12.013,Medicine_tweet_88,Multi #omics analysis of individuals during periods of weight loss &amp; gain  #systemsbiology,Extensive multi-omic profiling of the blood and microbiomes of healthy and insulin-resistant humans as they gain and lose weight reveals insights into the systemic impacts of weight gain.,Multi #omics analysis of individuals during periods of weight loss &amp; gain  #systemsbiology,"Graphical Abstract Highlights d Analysis of insulin-sensitive and -resistant individuals across multiple omes d We reveal molecular changes in the human body after modest short-term weight gain d Reversal of short-term weight gain eliminates negative molecular alterations d Open-access multi-omic resource for further bioinformatics developments Extensive multi-omic profiling of the blood and microbiomes of healthy and insulin-resistant humans as they gain and lose weight reveals insights into the systemic impacts of weight gain. As such, a more comprehensive molecular profiling approach may offer novel insights into the diversity of systemic responses to the increase in body fat stores.","[3.0, 5.0, 4.0, 5.0, 4.0]",Medicine,train,4.2,tweets,954036430682165248
10.1001/jamaophthalmol.2017.4512,Medicine_tweet_89,"In Women's Health Initiative participants with #cataract, those with #cataractsurgery may have longer survival.  ","Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care.","In Women's Health Initiative participants with #cataract, those with #cataractsurgery may have longer survival.  ","Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care. 6 Furthermore, the WHI database contains information on total and cause-specific mortality, which is not available in other large databases of patients with cataract surgery in the United States. 7 These factors make the WHI an ideal cohort in which to examine the interplay between eye disease and a wide variety of systemic and lifestyle factors in US women.","[3.0, 3.0, 3.0, 2.0]",Medicine,train,2.75,tweets,923579988414226432
10.1001/jamapediatrics.2013.455,Medicine_tweet_9,"Longer breastfeeding is associated with improved cognition at age 3 and 7.  Again, data are observational. #needrcts ","RESULTS Adjusting for sociodemographics, maternal intelligence, and home environment in linear regression, longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed).","Longer breastfeeding is associated with improved cognition at age 3 and 7.  Again, data are observational. #needrcts ","MAIN EXPOSURE Duration of any breastfeeding to age 12 months. RESULTS Adjusting for sociodemographics, maternal intelligence, and home environment in linear regression, longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed). Breastfeeding duration was not associated with Wide Range Assessment of Memory and Learning scores.","[5.0, 4.0, 5.0, 4.0, 4.0]",Medicine,train,4.4,tweets,370897635525136387
10.14814/phy2.13617,Medicine_tweet_90,Exposing preschoolers to an hour of bright light before bedtime almost completely shuts down their production of the sleep-promoting hormone melatonin. ,The magnitude of the circadian response to light may differ in young children and therefore understanding the phase shifting effects of light in this age group is necessary to support age-based recommendations for evening light exposure.,Exposing preschoolers to an hour of bright light before bedtime almost completely shuts down their production of the sleep-promoting hormone melatonin. ,"Although this study was not designed to assess changes in circadian timing (phase shifts) in response to an experimental light stimulus, this represents an area of rich investigation. The magnitude of the circadian response to light may differ in young children and therefore understanding the phase shifting effects of light in this age group is necessary to support age-based recommendations for evening light exposure. Because the early childhood years are a sensitive and vulnerable window in human development (Center on the Developing Child, 2010), future research should investigate the role of evening light exposure in health and disease in early life.","[5.0, 2.0, 2.0, 2.0, 3.0]",Medicine,train,2.8,tweets,971015501236375552
10.1098/rsos.171474,Medicine_tweet_91,"More evidence that playing violent video games is not associated with violent or aggressive behaviour in real life – this time from a registered report with a large sample of UK teens (N = 1,004).  ",Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours.,"More evidence that playing violent video games is not associated with violent or aggressive behaviour in real life – this time from a registered report with a large sample of UK teens (N = 1,004).  ","Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers. Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours. In other words, we found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games.","[2.0, 2.0, 4.0, 4.0]",Medicine,train,3.0,tweets,1095826758455066624
10.1038/s41467-018-07557-4,Medicine_tweet_92,"Latest from @username, up to 70% of our #arctic infrastructure is at risk of #climatechange induced permafrost degradation, affecting over 4 million people.

I'm getting a sinking feeling about all of this!

  ","Detrimental effects on engineered structures, socio-economic activities, and natural systems can, therefore, all be expected throughout the permafrost domain under climate warming 1 , particularly in high-risk areas with substantial urban and industrial centres such as Vorkuta and Novyi Urengoy in hot spots of infrastructure hazard in the Russian Arctic ( Fig.","Latest from @username, up to 70% of our #arctic infrastructure is at risk of #climatechange induced permafrost degradation, affecting over 4 million people.

I'm getting a sinking feeling about all of this!

  ","The potential harm to industrial facilities could be larger than estimated (pipelines: estimate = 32%, range = 24-70%; industrial areas: estimate = 25%, range = 20-64%) ( Fig. Detrimental effects on engineered structures, socio-economic activities, and natural systems can, therefore, all be expected throughout the permafrost domain under climate warming 1 , particularly in high-risk areas with substantial urban and industrial centres such as Vorkuta and Novyi Urengoy in hot spots of infrastructure hazard in the Russian Arctic ( Fig. adaptation strategies and structures such as insulation and thermosyphons that were not considered in this pan-Arctic study) can to some extent address both human-induced and naturally caused problems, their economic cost may be prohibitive at regional scales 32 .","[3.0, 4.0, 4.0, 3.0]",Medicine,train,3.5,tweets,1073308524707381248
10.3945/jn.113.188441,Medicine_tweet_93,What to eat when working those long hours at the office? Study shows instant noodles increase risk of heart disease - ,"However, the stronger association between instant noodle consumption $2 times/wk and metabolic syndrome among women after excluding participants taking blood pressure-lowering and lipid-lowering medications or who had a history of diabetes mellitus might indicate the robustness of that association.",What to eat when working those long hours at the office? Study shows instant noodles increase risk of heart disease - ,"First, we cannot infer a causal relation given our cross-sectional study design. However, the stronger association between instant noodle consumption $2 times/wk and metabolic syndrome among women after excluding participants taking blood pressure-lowering and lipid-lowering medications or who had a history of diabetes mellitus might indicate the robustness of that association. Second, dietary pattern construction by principal components analysis may be limited by subjectivity in the proper number of extracted factors and food-grouping methods .","[3.0, 4.0, 1.0, 2.0, 1.0]",Medicine,train,2.2,tweets,502708776219459586
10.1039/c3cs60122f,Medicine_tweet_94,"Lab notebooks in the digital era: ELNs in record keeping for chemistry &amp; other sciences: Bird, Willoughby, @username ",They note that the knowledge that a laboratory notebook comprises can be critical for establishing evidence in support of intellectual property rights and for refuting claims of research misconduct.,"Lab notebooks in the digital era: ELNs in record keeping for chemistry &amp; other sciences: Bird, Willoughby, @username ",119 He also presented a financial justification for electronic management of IP records. They note that the knowledge that a laboratory notebook comprises can be critical for establishing evidence in support of intellectual property rights and for refuting claims of research misconduct. 120 It is perhaps a sign of the times that this is one of only two publications in this survey to mention defence against claims of misconduct.,"[2.0, 3.0, 1.0, 3.0, 5.0]",Medicine,train,3.0,tweets,366952261068406785
10.1111/dom.13336,Medicine_tweet_95,Girls with menarche at age 10 years or younger are 18% more likely to develop T2D compared with girls with it at age 13 years or older. Nulliparous women are at greater risk T2D vs. women who have had at least 2.  @username @username,"Non-linear associations with diabetes were observed for age at menarche, parity and age at first birth.",Girls with menarche at age 10 years or younger are 18% more likely to develop T2D compared with girls with it at age 13 years or older. Nulliparous women are at greater risk T2D vs. women who have had at least 2.  @username @username,"Results: Over a median follow-up of 9 years, 4073 cases of diabetes were reported. Non-linear associations with diabetes were observed for age at menarche, parity and age at first birth. Notable trends in the prevalence of female-specific risk factors such as an increase in the rate of gestational diabetes (itself, a major risk factor for diabetes) observed in populations, 11 and a decline in the mean age of menarche 12 (in part attributable to the increase in childhood obesity) have added to the speculation that they may play a role in the diabetes pandemic.","[4.0, 2.0, 1.0, 3.0]",Medicine,train,2.5,tweets,992436255689408512
10.1177/0146167214565055,Medicine_tweet_96,Does having particular types of goals provoke superstitious behavior more so than others? ,"We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (contingent on external forces such as luck) will facilitate the achievement of learning goals, and will not use superstitious behavior to facilitate their achievement.",Does having particular types of goals provoke superstitious behavior more so than others? ,"Intrinsic motivation leads to a perception of internal (rather than external) locus of control , which is consistent with the idea that learning goals are judged internally-by oneself. We suggest that this internal sense of judgment and control for learning goals means that people do not believe that superstition (contingent on external forces such as luck) will facilitate the achievement of learning goals, and will not use superstitious behavior to facilitate their achievement. In Study 5, conditioning trials established positive or negative associations with several items.","[2.0, 5.0, 4.0]",Medicine,train,2.0,tweets,560262826816983041
10.1016/j.socscimed.2018.10.008,Medicine_tweet_97,Important paper out today with @username. Male infants and birth complications increase incidence of PND.  #pnd #ppd #babyboy #obgyn #episiotomy #csection #difficultbirth #inflammation #evolutionarymedicine,We found the odds of PND increased by 71-79% when male infants were born compared to female infants.,Important paper out today with @username. Male infants and birth complications increase incidence of PND.  #pnd #ppd #babyboy #obgyn #episiotomy #csection #difficultbirth #inflammation #evolutionarymedicine,"We found the odds of PND increased by 71-79% when male infants were born compared to female infants. The occurrence of birth complications increased the odds of PND by 174% compared to having no complications. Testing for interaction effects found that, while always at increased risk of PND, women with a tendency towards symptoms of depression, anxiety, and stress at other points in the life course had reduced odds of PND when experiencing birth complications, suggesting such women may elicit greater support.","[4.0, 5.0, 3.0, 5.0, 5.0]",Medicine,train,4.4,tweets,1058267550939668481
10.1093/eurpub/cky178,Medicine_easy_0,"""We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.""",We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.,"""Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles,"" the authors wrote. ""We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage."" ""Many people were not hired anymore as staff.""","Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles. We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage. In the worst affected regions, which faced up to 5% cuts, this would equate to a 2.5 percentage point fall in coverage.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37159214862&p=1pl&v=1&x=CcPjjUifeL13VJ3H086Sjg
10.1001/jamasurg.2014.2253,Medicine_easy_2,"The authors acknowledge limitations of their study, including that the decreasing rate of PTR could have primarily been the result of more effective systemic therapy or of greater reluctance by surgeons to operate on patients with asymptomatic stage IV CRC.","First, the decreasing rate of PTR could have been primarily the result of more effective systemic therapy or of greater reluctance among surgeons to operate on patients with asymptomatic stage IV CRC.","Results also show the median survival rate for stage IV CRC improved from 8.6 percent in 1988 to 17.8 percent in 2009. The authors acknowledge limitations of their study, including that the decreasing rate of PTR could have primarily been the result of more effective systemic therapy or of greater reluctance by surgeons to operate on patients with asymptomatic stage IV CRC. ""Despite the availability of more effective chemotherapeutic options, a considerable number of patients with stage IV CRC continue to undergo PTR.","Our study has several limitations. First, the decreasing rate of PTR could have been primarily the result of more effective systemic therapy or of greater reluctance among surgeons to operate on patients with asymptomatic stage IV CRC. The extent to which these factors contributed to the observed decreasing PTR rate is unknown.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2015/01/150114115508.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1080/02770903.2017.1299757,Medicine_easy_3,"Over a third (42.4 per cent) of students prescribed a short-acting '?2-agonist' inhaler felt uncomfortable using it at school, and 29.2 per cent reported not using this inhaler when wheezy.","Over a third (42.4%) of students prescribed a short-acting β2-agonist inhaler felt uncomfortable using it at school, and 29.2% (n = 173) reported not using this inhaler when wheezy.","The study, published in the Journal of Asthma, found that suboptimal asthma control was reported by 49.6 per cent of the students. Over a third (42.4 per cent) of students prescribed a short-acting '?2-agonist' inhaler felt uncomfortable using it at school, and 29.2 per cent reported not using this inhaler when wheezy. 56.4 per cent of those with regular inhaled corticosteroids did not take them as prescribed, and 41.7 per cent did not know what this inhaler was for.","Suboptimal asthma control was reported by 49.6% of students. Over a third (42.4%) of students prescribed a short-acting β2-agonist inhaler felt uncomfortable using it at school, and 29.2% (n = 173) reported not using this inhaler when wheezy. 56.4% (n = 220) of those with regular inhaled corticosteroids did not take them as prescribed, and 41.7% did not know what this inhaler was for.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/asthmatic-schoolchildren-are-uncomfortable-using-their-inhalers/
10.1001/jamaneurol.2017.4618,Medicine_easy_4,Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae.,"Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001).","A total of 101 patients (26.1 percent) had delayed neurological sequelae. Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae. The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2 percent and 90.2 percent, respectively.","Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001). The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2% (95% CI, 66.8%-83.7%) and 90.2% (95% CI, 86.8%-93.7%), respectively. In addition, the positive and negative predictive values were 73.1% (95% CI, 64.6%-81.6%) and 91.2% (95% CI, 87.9%-94.5%), respectively.",[5],Medicine,train,5.0,news,http://www.diagnosticimaging.com/article/imaging-may-identify-potential-delayed-neurological-sequelae-after-carbon-monoxide-poisoning
10.1377/hlthaff.2012.1030,Medicine_easy_5,"Even among lower-risk pregnancies, ""in which more limited variation might be expected,"" hospital cesarean rates varied 15-fold, from 2 percent to 37 percent.","Even for women with lower-risk pregnancies, in which more limited variation might be expected, cesarean rates varied fifteenfold, from 2.4 percent to 36.5 percent.","C-Section Rates Vary Widely Between Hospitals, Study Finds Rates ranged from 7 percent to 70 percent depending on the hospital. Even among lower-risk pregnancies, ""in which more limited variation might be expected,"" hospital cesarean rates varied 15-fold, from 2 percent to 37 percent. ""Because Medicaid pays for nearly half of U.S. births, government efforts to decrease variation are warranted.""","Working with 2009 data from 593 US hospitals nationwide, we found that cesarean rates varied tenfold across hospitals, from 7.1 percent to 69.9 percent. Even for women with lower-risk pregnancies, in which more limited variation might be expected, cesarean rates varied fifteenfold, from 2.4 percent to 36.5 percent. Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals.",[5],Medicine,train,5.0,news,http://abcnews.go.com/Health/section-rates-vary-widely-hospitals-study-finds/story?id=18656847
10.1016/j.jsams.2019.05.003,Medicine_easy_6,"""While for the majority of cancer patients, moderate to high intensity exercise will likely be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.""","Conclusions: While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.","""Research in this space has exponentially grown and consequently, the updated position stand now provides the foundation for Accredited Exercise Physiologists to ensure their exercise prescription is targeted towards improving cancer outcomes,"" Professor Hayes said. ""While for the majority of cancer patients, moderate to high intensity exercise will likely be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients."" This position statement allows for precision medicine through exercise.""","Additional specific exercise prescription considerations are provided for the presence of haematological, musculoskeletal, systemic, cardiovascular, lymphatic, gastrointestinal, genitourinary and neurological disease-and treatment-related concerns, as well as presence of co-morbid chronic disease. Conclusions: While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients. Targeted exercise prescription, which includes the provision of behaviour change advice and support, is needed to ensure greatest benefit (as defined by the patient) in the short and longer term, with low risk of harm.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39294284554&p=1pl&v=1&x=LXJKTkEMj4CRRK0Y-kPbZw
10.1377/hlthaff.2012.1030,Medicine_easy_7,"""Because Medicaid pays for nearly half of U.S. births, government efforts to decrease variation are warranted.""","Because Medicaid pays for nearly half of US births, government efforts to decrease variation are warranted.","Even among lower-risk pregnancies, ""in which more limited variation might be expected,"" hospital cesarean rates varied 15-fold, from 2 percent to 37 percent. ""Because Medicaid pays for nearly half of U.S. births, government efforts to decrease variation are warranted."" Read this story on www.medpagetoday.com.","Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals. Because Medicaid pays for nearly half of US births, government efforts to decrease variation are warranted. We focus on four promising directions for reducing these variations, including better coordinating maternity care, collecting and measuring more data, tying Medicaid payment to quality improvement, and enhancing patient-centered decision making through public reporting.",[5],Medicine,train,5.0,news,http://abcnews.go.com/Health/section-rates-vary-widely-hospitals-study-finds/story?id=18656847
10.1111/cdev.12250,Medicine_easy_8,"The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote.","The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers.","In fact, just the opposite happened. The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","Early reliance upon minor acts of delinquency to impress peers may thus lead to a greater likelihood of associating with deviance-prone peers, who in turn would only be impressed by more and more serious acts of deviance over time. The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers. Similarly, whereas minor levels of alcohol or substance use may impress a subgroup of peers in early adolescence, by early adulthood, such behavior would gain little notice, and it may take heavy drinking and more serious substance use to try to impress adult peers.",[5],Medicine,train,5.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1542/peds.2017-1330,Medicine_easy_9,"""Marijuana users who use other drugs are at highest risk for currently using SCs, so particular focus must be paid to these individuals to prevent increasingly dangerous and severe health outcomes among young users.""","Marijuana users who use other drugs in particular are at highest risk for currently using SCs, so particular focus needs to be paid to these individuals at high risk.","Although previous studies have revealed that marijuana users are at high risk for SC use, this study further revealed risk factors among current marijuana users that increase risk of current use and higher-frequency use of SCs. ""Our research calls for future prevention focused primarily on marijuana users, especially male and/or African-American marijuana users who appear to be at greatest risk for frequent use,"" says Palamar. ""Marijuana users who use other drugs are at highest risk for currently using SCs, so particular focus must be paid to these individuals to prevent increasingly dangerous and severe health outcomes among young users.""","Although previous studies have revealed that marijuana users are at high risk for use, this study revealed risk factors among current marijuana users that increase risk of current use and higher-frequency use of SCs. Prevention needs to be focused primarily on marijuana users, especially marijuana users with risk factors discovered in this analysis. Marijuana users who use other drugs in particular are at highest risk for currently using SCs, so particular focus needs to be paid to these individuals at high risk.",[5],Medicine,train,5.0,news,http://www.futurity.org/synthetic-cannabinoids-spice-1549022-2/
10.1001/jama.2014.15690,Medicine_easy_10,Reduction in the incidence of colorectal cancer may influence the overall benefitrisk profile of aspirin.,Reduction in the incidence of colorectal cancer may influence the overall benefit-risk profile of aspirin.,"The authors write that despite inconsistent evidence for the benefit of aspirin in primary prevention of cardiovascular events, the benefits in secondary prevention are well documented, including in Japanese patients. Reduction in the incidence of colorectal cancer may influence the overall benefitrisk profile of aspirin. Further analyses of [this] study data are planned, including analysis of deaths associated with cancers, to allow more precise identification of the patients for whom aspirin treatment may be most beneficial.","No effect on fatal myocardial infarction was observed, but a modest nonsignificant reduction was apparent for all-cause mortality. Reduction in the incidence of colorectal cancer may influence the overall benefit-risk profile of aspirin. Further analyses of the JPPP study data are planned, including analysis of deaths associated with cancers, to allow more precise identification of the patients for whom aspirin treatment may be most beneficial.",[5],Medicine,train,5.0,news,http://www.newswise.com/articles/effect-of-once-daily-low-dose-aspirin-on-cv-death-and-other-outcomes
10.1377/hlthaff.2012.1030,Medicine_easy_11,"Cesarean rates increased from 20.7 percent in 1996 to 32.8 percent in 2011, according to the Minnesota researchers.",Cesarean rates increased from 20.7 percent of all deliveries in 1996 to 32.8 percent in 2011.,"""The scale of this variation signals potential quality issues that should be quite alarming to women, clinicians, hospitals and policymakers,"" she added.Cesarean delivery is the most common surgery in the United States, performed on 1.67 million women each year. Cesarean rates increased from 20.7 percent in 1996 to 32.8 percent in 2011, according to the Minnesota researchers. ""Cesarean deliveries save lives, and every woman who needs one should have one,"" Kozhimannil said.","We focus on four promising directions for reducing these variations, including better coordinating maternity care, collecting and measuring more data, tying Medicaid payment to quality improvement, and enhancing patient-centered decision making through public reporting. Cesarean rates increased from 20.7 percent of all deliveries in 1996 to 32.8 percent in 2011. 3 In international comparisons, US cesarean rates exceed those for similar countries, without measurable clinical benefit.",[5],Medicine,train,5.0,news,http://www.webmd.com/baby/news/20130304/c-section-rates-vary-widely-at-us-hospitals
10.1001/jamasurg.2018.0672,Medicine_easy_12,The difference in the global score of SwQoR between inadequate and sufficient FHL (37.4 and 17.7) was statistically significant.,There was a statistically significant difference in the global score of SwQoR (SD) between inadequate (37.4 [34.7]) and sufficient FHL (17.7 [21.0]) (P < .001).,"The researchers found that the inadequate and problematic FHL groups had a global score of SwQoR that indicated poor recovery (37.4 and 22.9, respectively). The difference in the global score of SwQoR between inadequate and sufficient FHL (37.4 and 17.7) was statistically significant. Compared to patients with sufficient FHL, patients with inadequate or problematic FHL had a lower health-related quality of life in terms of EuroQoL-visual analog scale scores, physical function, bodily pain, vitality, social functioning, mental health, and physical component summary.","The global score of SwQoR indicated poor recovery in both inadequate (37.4) and problematic (22.9) FHL. There was a statistically significant difference in the global score of SwQoR (SD) between inadequate (37.4 [34.7]) and sufficient FHL (17.7 [21.0]) (P < .001). The patients with inadequate or problematic FHL had a lower health-related quality of life than the patients with sufficient FHL in terms of EuroQol-visual [11.3], and 45 [10.1], respectively; P = .004).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33900191633&p=1pl&v=1&x=U2NKEgQRLXmLRbYHpHEUVQ
10.1377/hlthaff.2018.05101,Medicine_easy_13,"""Policies that incentivize providers to adopt telehealth could be an important way to increase access for underserved populations.""",Policies that incentivize providers and health systems to use telehealth could be an important way to increase access to care for underserved populations.,"But underserved populations -- such as low-income, rural and Medicaid populations -- did not use video-based telehealth as widely as other demographic groups. The researchers identified this trend across the U.S., even in states with less restrictive telehealth policies -- suggesting that providers and patients will need incentives to adopt the service that go beyond removing regulatory restrictions. ""Policies that incentivize providers to adopt telehealth could be an important way to increase access for underserved populations.""","Making telehealth easy to use is important but might not be enough to make providers or health systems invest the time, energy, and money needed to begin offering the service or expand its use. Policies that incentivize providers and health systems to use telehealth could be an important way to increase access to care for underserved populations. For example, offering financial incentives for providers to adopt telehealth may lead to increased usage, as payment incentives led to the increased adoption and use of electronic health records and patient-centered medical home status in safety-net clinics.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37884913467&p=1pl&v=1&x=MrQLspWtUsUM_TYVPtFo1w
10.1016/j.jsams.2019.05.003,Medicine_easy_14,"""While for the majority of cancer patients, moderate to high intensity exercise will likely be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.""","While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients.","""Research in this space has exponentially grown and consequently, the updated position stand now provides the foundation for Accredited Exercise Physiologists to ensure their exercise prescription is targeted towards improving cancer outcomes,"" Professor Hayes said. ""While for the majority of cancer patients, moderate to high intensity exercise will likely be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients."" This position statement allows for precision medicine through exercise.""","Overall, evidence supports that the implementation of exercise prescription brings with it reduced morbidity, improved function and quality of life, and potential for improved survival, with very low risk of harm. While for the majority, multimodal, moderate to high intensity exercise will be appropriate, there is no set prescription and total weekly dosage that would be considered evidence-based for all cancer patients. Appropriate exercise prescription for cancer patients needs to be targeted and individualised according to patient-and cancer-specific considerations.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39294284554&p=1pl&v=1&x=LXJKTkEMj4CRRK0Y-kPbZw
10.1038/nature13850,Medicine_easy_15,"According to the study, ""the unexpected morphology suggests that the magnetic field's role during the accretion of a T Tauri star is more complex than the current theoretical understanding,"" and that magnetic fields are important in forming a planetary system like our own.",The unexpected morphology suggests that the role of the magnetic field in the accretion of a T Tauri star is more complex than our current theoretical understanding.,"These CARMA observations found the first detection of the magnetic field morphology in a T Tauri star disk. According to the study, ""the unexpected morphology suggests that the magnetic field's role during the accretion of a T Tauri star is more complex than the current theoretical understanding,"" and that magnetic fields are important in forming a planetary system like our own. While the magnetic field morphology appears significantly more toroidal than poloidal, neither morphology is a good fit.","From this we conclude that the magnetic field inside the disk at this scale cannot be dominated by a vertical component, though a purely toroidal field also does not fit the data well. The unexpected morphology suggests that the role of the magnetic field in the accretion of a T Tauri star is more complex than our current theoretical understanding. Although HL Tau is a T Tauri star, it is considered to be in an early stage of development owing to its bipolar outflow 14 and possible residual envelope 15 .",[5],Medicine,train,5.0,news,http://www.futurity.org/stars-magnetic-field-803342/
10.1080/02770903.2017.1299757,Medicine_easy_16,A total of 799 children in 24 schools completed the questionnaire and 689 were included for analysis.,Results: A total of 799 children completed the questionnaire; 689 (86.2%) were included for analysis.,"The researchers say the results should prompt more intense clinical monitoring, and suggest a need for interventions aimed at addressing poor asthma control in UK schoolchildren. A total of 799 children in 24 schools completed the questionnaire and 689 were included for analysis. The study, published in the Journal of Asthma, found that suboptimal asthma control was reported by 49.6 per cent of the students.","Results: A total of 799 children completed the questionnaire; 689 (86.2%) were included for analysis. Suboptimal asthma control was reported by 49.6% of students. Over a third (42.4%) of students prescribed a short-acting β2-agonist inhaler felt uncomfortable using it at school, and 29.2% (n = 173) reported not using this inhaler when wheezy.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/asthmatic-schoolchildren-are-uncomfortable-using-their-inhalers/
10.1007/s10803-017-3154-9,Medicine_easy_17,"""In spite of its limitations,"" the study authors concluded, ""the present findings reveal indicators that may be useful for identifying children and adolescents at greater risk of psychiatric hospitalization as well as other potential targets for individual and family intervention.""","In spite of its limitations, the present findings reveal indicators that may be useful for identifying children and adolescents at greater risk of psychiatric hospitalization as well as offer potential targets for individual and family intervention aimed at reducing the likelihood of requiring acute psychiatric services.","Also, the study measured associations of risk factors with hospitalization but doesn't prove they were the cause of hospital visits. But the study authors wrote that the risk factors they identified may be worth addressing before young autism patients reach the point where hospitalization becomes necessary. ""In spite of its limitations,"" the study authors concluded, ""the present findings reveal indicators that may be useful for identifying children and adolescents at greater risk of psychiatric hospitalization as well as other potential targets for individual and family intervention.""","Lastly, there may be a variety of factors not measured in the present study that contribute to greater risk for hospitalization including outpatient psychiatric care, home-based behavioral services, school setting or day programming, and the availability of other individual and family services. In spite of its limitations, the present findings reveal indicators that may be useful for identifying children and adolescents at greater risk of psychiatric hospitalization as well as offer potential targets for individual and family intervention aimed at reducing the likelihood of requiring acute psychiatric services. Our results underscore the importance of a multi-disciplinary approach to the assessment and treatment of children and adolescents with ASD that addresses behavioral, psychological/ psychiatric, adaptive, sleep, and medical functioning in order to decrease behavioral crises and the utilization of inpatient psychiatric services.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/study-of-kids-with-autism-identifies-hospitalization-risk-factors/
10.1016/j.jsams.2019.05.003,Medicine_easy_19,"""As exercise capacity improves, progression towards longer sessions of at least 20 minutes duration on most days of the week is recommended.""","As exercise capacity improves, progression towards longer sessions of at least 20 min duration on most days of the week is recommended.","""The type, duration, frequency, intensity and total volume of exercise prescription needs to be tailored to the patient's needs and priorities,"" Professor Galvao said. ""For example, for patients with a low level of fitness, or those with advanced stage disease, a starting exercise prescription may need to involve multiple short bouts of five to ten minutes, to accumulate at least 20 minutes on any given day. ""As exercise capacity improves, progression towards longer sessions of at least 20 minutes duration on most days of the week is recommended.""","For deconditioned patients, immediately post-surgery and/or for those with advanced stage disease, a starting exercise prescription may need to involve multiple short bouts (5-10 min duration) daily, to accumulate at least 20 min on any given day. As exercise capacity improves, progression towards longer sessions of at least 20 min duration on most days of the week is recommended. The 20 min cut-point being proposed (which has also been suggested by others previously ) is not distinct and less duration per day may be more optimal for some patients (e.g., palliative patients with lung cancer).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39294284554&p=1pl&v=1&x=LXJKTkEMj4CRRK0Y-kPbZw
10.1038/s41598-018-30980-y,Medicine_easy_21,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day.","Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.","Change in memory accuracy also did not differ when probed after a nap compared to the change in memory accuracy after an interval awake. However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1038/s41467-018-07557-4,Medicine_easy_22,"""Our results demonstrate that one-third of pan-Arctic infrastructure and 45 percent of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment.",Our results demonstrate that one-third of pan-Arctic infrastructure and 45% of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment.,"""We show that nearly four million people and 70 percent of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost,"" the team wrote. ""Our results demonstrate that one-third of pan-Arctic infrastructure and 45 percent of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment. Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached.""","We show that nearly four million people and 70% of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost. Our results demonstrate that one-third of pan-Arctic infrastructure and 45% of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment. Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37952048427&p=1pl&v=1&x=WVBbJHZ_CDGkehwcKPFvdQ
10.1016/j.jadohealth.2015.02.018,Medicine_easy_23,"Before college, 28 percent of the women said they had experienced attempted or completed rape.","Before entering college, 28% of women had experienced attempted or completed rape.","By the time they started their sophomore year, 11 percent of the women said they had been raped by force, and nearly 16 percent said they had been raped while incapacitated, either as a teen or in college. Before college, 28 percent of the women said they had experienced attempted or completed rape. The study highlights the need for a ""trauma-informed approach"" in college messaging that is sensitive to rape survivors, notes an editorial in the Journal of Adolescent Health.","In addition, this study provides temporal resolution unavailable in most previous reports. Before entering college, 28% of women had experienced attempted or completed rape. During their first year, one of six female students had experienced A/C IR or A/C FR.",[5],Medicine,train,5.0,news,http://www.csmonitor.com/USA/Education/2015/0520/Preventing-college-rape-why-freshman-year-is-key-especially-for-past-victims
10.1001/jama.2013.277165,Medicine_easy_25,"""Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy.",Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy.,"Study anticoagulant was discontinued because of bleeding in 242 patients (4.7 percent) in the otamixaban group and in 95 patients (1.7 percent) in the UFH-plus-eptifibatide group. ""Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy. These findings do not support the use of otamixaban for patients with NSTE-ACS undergoing planned early percutaneous coronary intervention,"" the authors conclude.","Other regimens might have offered a different benefit-risk profile, 19, 26, 27 but because otamixaban did not display superior efficacy and did show worse safety, this point is moot. Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy. These findings do not support the use of otamixaban for patients with NSTE-ACS undergoing planned early percutaneous coronary intervention.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/09/130901153354.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1093/eurpub/cky178,Medicine_easy_26,"""Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles,"" the authors wrote.",Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles.,"That simple narrative isn't quite accurate anymore. ""Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles,"" the authors wrote. ""We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.""","Second, we added the German-speaking province of Bolzano However, none of the main results was qualitatively changed, although the coefficient estimates were slightly attenuated. Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles. We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37159214862&p=1pl&v=1&x=CcPjjUifeL13VJ3H086Sjg
10.1093/eurpub/cky178,Medicine_easy_27,"""Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles,"" the authors write.",Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles.,"On average, a 0.5 percentage point decline in MMR coverage corresponds to a 1% cut in spending. ""Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles,"" the authors write. It will be important to monitor these developments, not only to inform policy in Italy but across Europe where many countries now face similar problems.""","Second, we added the German-speaking province of Bolzano However, none of the main results was qualitatively changed, although the coefficient estimates were slightly attenuated. Our analysis suggests that austerity measures adopted in Italy contributed significantly to the resurgence of measles. We estimated that each 1% reduction in real public health expenditure per-capita corresponded to a 0.5 percentage points reduction in MMR coverage.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37085206177&p=1pl&v=1&x=Z0WLlSNB6z5fzDN5rayk1A
10.1016/j.mayocp.2014.07.004,Medicine_easy_28,"""As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support.","As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support.","A combination of prescription medication along with limited behavioral support was also more effective than unaided quitting. ""As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support. A major strength of our study is the use of a representative sample of the English population that was sufficiently large to detect an effect of specialist behavioral support despite its low prevalence,"" says Dr. Kotz.","Finally, our sample size was too small for comparing the differential effectiveness of different prescription medications. As far as we are aware, our study is the first prospective cohort study comparing prescription medication when offered with specialist behavioral support with prescription medication offered without such support. A major strength of our study is the use of a representative sample of the English population that was sufficiently large to detect an effect of specialist behavioral support despite its low prevalence.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141008083514.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41598-018-30980-y,Medicine_easy_29,Yet nap slow wave activity also predicted greater overnight improvement in memory.,Yet nap slow wave activity also predicted greater overnight improvement in memory.,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory. Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude.",Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory. These results suggest that sleep bouts can interact to benefit memory in early childhood.,[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jamasurg.2018.0672,Medicine_easy_30,Researchers believe this is the first study that has examined whether there is an association between postoperative recovery and functional health literacy in patients undergoing day surgery.,"To our knowledge, this is the first study that has examined whether there is any association between postoperative recovery and functional health literacy in patients undergoing day surgery.","""Patients are spending less time in the hospital, and this places greater demands on the patients and their relatives. Researchers believe this is the first study that has examined whether there is an association between postoperative recovery and functional health literacy in patients undergoing day surgery. In the study, 60.6 percent of patients reported sufficient functional health literacy, 31.7 patients had problematic functional health literacy and 7.7 percent had inadequate functional health literacy.","There were no differences between the groups in health care contacts ( Table 4) . To our knowledge, this is the first study that has examined whether there is any association between postoperative recovery and functional health literacy in patients undergoing day surgery. We found that patients with inadequate FHL experienced a poor recovery; that is, they reported higher scores in SwQoR on postoperative day 14 compared with patients with sufficient FHL.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33897057585&p=1pl&v=1&x=gsIoyrhoCs5f3L7Wv3ex4w
10.1073/pnas.1505114112,Medicine_easy_31,"""Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during the teenage years,"" the authors write.","Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years.","They also demonstrated prolonged heightened brain sensitivity to sound details. [related]

All participants improved in language skills important for language and reading, but the improvement was greater for those in music classes, compared with the ROTC group. ""Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during the teenage years,"" the authors write.","These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls. Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years. Here, we show that inschool music training begun in high school prolongs the stability of subcortical sound processing and accelerates maturation of cortical auditory responses.",[5],Medicine,train,5.0,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1038/s41467-018-07557-4,Medicine_easy_32,"""The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved,"" the authors write.","The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved.","The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change. ""The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved,"" the authors write. However, after 2050, attaining the Paris Agreement goals would make a clear difference in potential damage to infrastructure.","Our results demonstrate that ca. The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved. Results show that by 2050 3.6 million people, which constitutes about three quarters of the current population in the Northern Hemisphere permafrost area, may be affected by damage to infrastructure associated with permafrost thaw (Fig.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37952353365&p=1pl&v=1&x=z8k6aIsKNtvV0TWFOzO7Gg
10.1001/jama.2015.1693,Medicine_easy_34,"""These findings do not support the use of a balloon-expandable stent for patients with intracranial arterial stenosis,"" the authors conclude.",These findings do not support the use of a balloon-expandable stent for patients with symptomatic intracranial arterial stenosis.,"A measure of disability worsened in more patients in the stent group than in the medical group. ""These findings do not support the use of a balloon-expandable stent for patients with intracranial arterial stenosis,"" the authors conclude. ""For endovascular therapy (e.g., angioplasty alone or new stents) to have any role, multicenter pilot studies will be required to establish the safety and potential efficacy of these devices in carefully defined patient populations.","Worsening of baseline disability score (modified Rankin Scale) occurred in more patients in the stent group (14/58; 24.1% [95% CI, 13.9%-37.2%]) vs the medical group (6/53; 11.3% [95% CI,.0%]) (P = .09).The EuroQol-5D showed no difference in any of the 5 dimensions between groups at 12-month follow-up. These findings do not support the use of a balloon-expandable stent for patients with symptomatic intracranial arterial stenosis. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00816166.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2015/03/150324120611.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jama.2015.1693,Medicine_easy_35,The 1-year outcome of stroke or hard TIA occurred in more patients in the stent group (36.2 percent) vs the medical group (15.1 percent).,"The 1-year primary outcome of stroke or hard TIA occurred in more patients in the stent group (21/58; 36.2% [95% CI, 24.0-49.9]) vs the medical group (8/53; 15.1% [95% CI, 6.7-27.6]) (P = .02).",Intracranial hemorrhage occurred in 5 patients (8.6 percent) in the stent group and in 0 in the medical group. The 1-year outcome of stroke or hard TIA occurred in more patients in the stent group (36.2 percent) vs the medical group (15.1 percent). Thirty day all-cause death was 3 of 58 patients (5.2 percent) in the stent group and 0 in the medical group.,"Intracranial hemorrhage within 30 days occurred in more patients in the stent group (5/58; 8.6% [95% CI, 2.9%-19.0%]) vs none in the medical group (95% CI, 0%-5.5%) (P = .06). The 1-year primary outcome of stroke or hard TIA occurred in more patients in the stent group (21/58; 36.2% [95% CI, 24.0-49.9]) vs the medical group (8/53; 15.1% [95% CI, 6.7-27.6]) (P = .02). Worsening of baseline disability score (modified Rankin Scale) occurred in more patients in the stent group (14/58; 24.1% [95% CI, 13.9%-37.2%]) vs the medical group (6/53; 11.3% [95% CI,.0%]) (P = .09).The EuroQol-5D showed no difference in any of the 5 dimensions between groups at 12-month follow-up.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2015/03/150324120611.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1002/cncr.29575,Medicine_easy_36,"""Our nomograms make it easier to derive individualized predictions of patient outcome; they allow physicians to recognize the risk of distant metastasis or tumor-related death after treatment and provide a more informative explanation for their patients.""",Our nomograms make it easier to derive individualized predictions of patient outcome; they allow physicians to recognize the risk of distant metastasis or tumor-related death after treatment and provide a more informative explanation for their patients.,"""It is not unusual for musculoskeletal oncologists to encounter patients who develop distant metastasis or suffer tumor-related death even though they receive identical definitive treatment, and the ability to identify such higher risk patients would undoubtedly be valuable,"" study authors concluded. ""Our nomograms make it easier to derive individualized predictions of patient outcome; they allow physicians to recognize the risk of distant metastasis or tumor-related death after treatment and provide a more informative explanation for their patients."" They added that the study is limited by its retrospective nature, but that this tool can be used for patient counseling and establishing post-surgical surveillance strategies.","However, it cannot be denied that the appropriate timing of follow-up and the planning of imaging tests should be stratified according to the degree of risk in individual patients. Our nomograms make it easier to derive individualized predictions of patient outcome; they allow physicians to recognize the risk of distant metastasis or tumor-related death after treatment and provide a more informative explanation for their patients. Although they are brief instruments and easy to use, a nomogram that has the potential Figure 2 .",[5],Medicine,train,5.0,news,http://www.cancernetwork.com/sarcoma/nomograms-help-predict-survival-outcomes-osteosarcoma-patients
10.1038/s41598-018-30980-y,Medicine_easy_39,"Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude.",These results suggest that sleep bouts can interact to benefit memory in early childhood.,"Yet nap slow wave activity also predicted greater overnight improvement in memory. Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude. Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children.""","Yet nap slow wave activity also predicted greater overnight improvement in memory. These results suggest that sleep bouts can interact to benefit memory in early childhood. Thus, enhancing emotional learning at this young age has wide-reaching and long-lasting impact.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jama.2014.15690,Medicine_easy_40,"""Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors,"" researchers wrote.","Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors.","The study showed no difference in risks of fatal or non-fatal heart event deaths between the two groups. ""Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors,"" researchers wrote. Researchers however said aspirin users should not immediately get off medication before consulting their doctors about risks and benefits.","Reduction in the incidence of colorectal cancer may influence the overall benefit-risk profile of aspirin. Further analyses of the JPPP study data are planned, including analysis of deaths associated with cancers, to allow more precise identification of the patients for whom aspirin treatment may be most beneficial. Once-daily, low-dose aspirin did not significantly reduce the risk of the composite outcome of cardiovascular death, nonfatal stroke, and nonfatal myocardial infarction among Japanese patients 60 years or older with atherosclerotic risk factors.",[5],Medicine,train,5.0,news,http://www.counselheal.com/articles/13333/20141120/aspirin-cut-heart-problems-risk.htm
10.1007/s13524-014-0321-x,Medicine_easy_41,Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.,Young parents have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.,"Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","In the long-run, there are no differences between men and women. Young parents have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s13578-015-0003-4,Medicine_easy_44,"I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3b in the aging rat hearts.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3β in the aging rat hearts.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3b in the aging rat hearts. We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3β in the aging rat hearts. We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.",[5],Medicine,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1001/jamaneurol.2017.4618,Medicine_easy_45,Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae.,Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae.,"In addition, the positive and negative predictive values were 73.1 percent and 91.2 percent, respectively. The researchers concluded that the presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae. Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae.",The presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae. Diffusion-weighted imaging during the acute phase of carbon monoxide poisoning may therefore help identify patients at risk of developing these debilitating sequelae. Documenting acute lesions that can potentially indicate the subsequent development of DNS could give clinicians and researchers useful information for understanding the pathophysiology of DNS and targeting prevention.,[5],Medicine,train,5.0,news,http://www.diagnosticimaging.com/article/imaging-may-identify-potential-delayed-neurological-sequelae-after-carbon-monoxide-poisoning
10.1186/s13578-015-0003-4,Medicine_easy_47,"In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts.","In conclusion, these results demonstrate that exogenous H 2 S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3β pathway in the aging rat hearts.","LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts. These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.","LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H 2 S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H 2 S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3β pathway in the aging rat hearts. These findings suggested that H 2 S might be a novel target for the treatment of aging cardiovascular diseases.",[5],Medicine,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1038/s41467-018-08278-4,Medicine_easy_48,"""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper.",These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound.,"That cartilage is a key part of joints, and shows definite progress in limb regeneration. ""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper. The results of the study showed that the regeneration process was most advanced when BMP2 was applied first, with BMP9 added a week after - in this case it led to the growth of more complete joint structures, even with some connections to the bone.",Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint. These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound. Transient treatment of the amputation wound with BMP induces formation of an endochondral ossification center that organizes the regeneration response of the amputated stump bone .,[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1038/s41598-018-30933-5,Medicine_easy_49,"In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food.","In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food.","What makes the study of Dr. Krasheninnikova's study so important and novel is that no previous studies of birds have tested decision-making using token exchange methodology. In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food. Finally, two conditions presented a situation where there was no difference between the immediate and the future gain, so that the most economic decision was to consume the food immediately.""","With this in mind, it is possible to hypothesise that the feeding specialists (the great green and the blue-throated macaws) might encounter a greater need for optimal decision-making as to where and when to go more often than feeding generalists (the African grey parrots and the blue-headed macaws), who may opportunistically take any food they encounter. In three conditions the subject could increase its payoff by choosing the token over the immediately available food, whereas in one condition, choosing the token led to a lower payoff than choosing the food. Finally, two conditions presented a situation where there was no difference between the immediate and the future gain, so that the most economic decision was to consume the food immediately.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37046481434&p=1pl&v=1&x=hbAvZo2c40WZuNN_G5gurQ
10.1016/j.scitotenv.2019.04.266,Medicine_easy_50,"""Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited un-intended consequences on more vulnerable communities,"" the authors write.","Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited unintended consequences on more vulnerable communities.","From questionnaires administered to both seller and buyers, the team found that most consumers bought bushmeat not because they needed the protein, but because they preferred the taste of it to livestock or they saw it as a healthier choice. ""Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited un-intended consequences on more vulnerable communities,"" the authors write. The study found that, in general, the threat of punishment for breaking Laos's laws controlling the trade in wild animals appeared to do little to dissuade vendors.","This suggests that the cost of law enforcement can be internalized by wildlife vendors as part of their business operations, while this cost may not be tolerable at the individual level for a wildlife consumer. Here again, a good understanding of wildlife consumer demography, economic status, and motivations is essential to the design of effective policy with limited unintended consequences on more vulnerable communities. Doing so, we demonstrated high rates of direct contact between bushmeat and people visiting the market, highlighting that this may be an under-estimated route of disease transmission in the bushmeat system.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39231575932&p=1pl&v=1&x=ugOkJg6MHSJ-5jXepqCzLA
10.1186/s13578-015-0003-4,Medicine_easy_51,"We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts.","We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3b in the aging rat hearts. We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3β in the aging rat hearts. We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.",[5],Medicine,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1038/s41598-018-25573-8,Medicine_easy_53,The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature.,The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature.,"The scientists had similar results when they used ovarian tumor samples taken directly from patients, showing that their chicken egg model provides a system for replicating human cancer. The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature. No significant damage to various organs in the chicken embryo occurred.","The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature. No significant damage to various organs in the chicken embryo occurred. In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1007/s00125-014-3400-z,Medicine_easy_54,"They conclude: ""This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection.",Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection.,"They add: ""Taiwan has relatively low type 1 diabetes incidence; we believe that the marked escalation of the said incidence in recent decades can be largely attributed to the highly endemic spread of enterovirus infection in Taiwanese children, given that there has been little gene flow and genetic drift in such a short period."" They conclude: ""This nationwide retrospective cohort study found a positive correlation of type 1 diabetes with EV infection. Our results suggest that preventive strategies, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.""","The HRs of type 1 diabetes in children with allergic rhinitis, bronchial asthma or either one of these atopic diseases showed more variation than in those children without these diseases. Conclusions/interpretation This nationwide retrospective cohort study found a positive correlation between type 1 diabetes and EV infection. The results suggest that a preventive strategy, such as an effective vaccine against EV infection, may lessen the incidence of type 1 diabetes in Taiwan.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141017183715.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamasurg.2018.0672,Medicine_easy_55,"""Health literacy is a relevant factor to consider for optimizing postoperative recovery in patients undergoing day surgery,"" the researchers conclude.",Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery.,"Also, patients with inadequate functional health literacy had a lower health-related quality of life in terms of physical function, bodily pain, vitality, social functioning, mental health and physical aspects. The researchers note that they did not have data on education or socioeconomic status, nor were they aware of how many can speak and read Swedish, which would also pose a challenge to understanding healthcare information, and will require further research. ""Health literacy is a relevant factor to consider for optimizing postoperative recovery in patients undergoing day surgery,"" the researchers conclude.","CONCLUSIONS AND RELEVANCE Inadequate FHL in patients undergoing day surgery was associated with poorer postoperative recovery and a lower health-related quality of life. Health literacy is a relevant factor to consider for optimizing the postoperative recovery in patients undergoing day surgery. 6 Considering this, the association between FHL and postoperative recovery in patients undergoing day surgery needs to be assessed.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33897057585&p=1pl&v=1&x=gsIoyrhoCs5f3L7Wv3ex4w
10.1038/s41467-018-04906-1,Medicine_easy_56,"""Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display.""","Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display.","This fingerprint sensor array has a high resolution with good transparency,"" the researchers said. ""Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display."" Not only that, the technology could also potentially allow smartphone manufacturers to extend the fingerprint sensor's coverage on a larger portion of a smartphone display.","This sensor with the hybrid electrode also operates at high frequencies with negligible degradation in its performance against various noise signals from mobile devices. Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display. Therefore, biometrics is a promising approach for ensuring user privacy.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1038/s41598-018-26198-7,Medicine_easy_57,"""Together, our results suggest that pro-resolution mechanisms may act in concert with increased cytotoxic immunity to reduce the growth of tumors in response to stretching,"" the team concludes.","Together, our results suggest that pro-resolution mechanisms may act in concert with increased cytotoxic immunity to reduce the growth of tumors in response to stretching.","Their measurements showed that levels of RvD1 and RvD2 were significantly higher in the stretch group. ""Together, our results suggest that pro-resolution mechanisms may act in concert with increased cytotoxic immunity to reduce the growth of tumors in response to stretching,"" the team concludes. They highlight the ""interesting possibility"" that stretching could effectively keep inflammation under control, without suppressing the natural cytotoxic immune response against the cancer cells, and then rescuing the cytotoxic function of exhausted T cells.","We therefore measured levels of SPMs within tumors and found that levels of RvD1 and RvD2 were both significantly greater in stretch vs. no-stretch mice (p = 0.04, Fig. Together, our results suggest that pro-resolution mechanisms may act in concert with increased cytotoxic immunity to reduce the growth of tumors in response to stretching. To our knowledge, this is the first report of reduced cancer growth in response to stretching.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34125675804&p=1pl&v=1&x=EIuTbzUDbEKkr7kvXb-kdg
10.1038/s41598-018-30933-5,Medicine_easy_58,"Furthermore, ""When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff.","When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff.","And, parrots of the larger macaw species actually did as well or better than primates who have been studied in similar experiments. Furthermore, ""When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff. They did so regardless of the value of the immediate gain.""","These findings parallel earlier findings in primates and suggest that the parrots indeed attributed value to the tokens. When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff. They did so regardless of the value of the immediate gain, i.e., low (condition 1) or medium (condition 2).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37046481434&p=1pl&v=1&x=hbAvZo2c40WZuNN_G5gurQ
10.1038/s41598-018-25573-8,Medicine_easy_60,No significant damage to various organs in the chicken embryo occurred.,No significant damage to various organs in the chicken embryo occurred.,"The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature. No significant damage to various organs in the chicken embryo occurred. In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered,"" write the investigators.","The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature. No significant damage to various organs in the chicken embryo occurred. In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1001/jamainternmed.2016.0157,Medicine_easy_62,"""From a public health perspective, our study supports partnership of app developers, distributors, and regulatory bodies to set and follow standards for safe, validated mHealth technologies,"" the researchers conclude.","From a public health perspective, our study supports partnership of app developers, distributors, and regulatory bodies to set and follow standards for safe, validated mHealth technologies.","These measurements correlated with the lowest possible accuracy grade in all categories by British Hypertensive Society scoring. These study findings demonstrate that the mHealth app produced highly inaccurate readings, which could give more than three-fourths (77.5%) of persons with hypertensive BP levels false reassurance that their BP is in the nonhypertensive range. ""From a public health perspective, our study supports partnership of app developers, distributors, and regulatory bodies to set and follow standards for safe, validated mHealth technologies,"" the researchers conclude.","Hence, we remain concerned that individuals may use these apps to assess their BP and titrate therapy. From a public health perspective, our study supports partnership of app developers, distributors, and regulatory bodies to set and follow standards for safe, validated mHealth technologies. Between its release on June 5, 04, and removal on July 0, 05 (4 days), the IBP app spent 56 days as one of the top 50 best-selling iPhone apps; at least 950 copies of this $4.99 app were sold on each of those days.",[5],Medicine,train,5.0,news,http://www.oncologynurseadvisor.com/instant-blood-pressure-mobile-app-fails-validation-study/article/484459/
10.1038/s41598-018-25573-8,Medicine_easy_63,"These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.""",These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer.,"Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer."" ""We were surprised when the tumor was formed in three days,"" notes Dr. Tamanoi.","Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor. These results point to the remarkable efficacy of our nanoparticle based drug delivery system and suggests the value of the chicken egg tumor model for testing novel therapies for ovarian cancer. Tumor recurrence and metastasis are primarily responsible for the 70% five-year mortality of advanced EOC.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1038/s41598-018-25573-8,Medicine_easy_64,"Furthermore, we observed excellent tumor accumulation of the nanoparticles.","Furthermore, we observed excellent tumor accumulation of the nanoparticles.","""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles. Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor.","The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles. Lastly, a tumor could be established in the egg using tumor samples from ovarian cancer patients and that our nanoparticles were effective in eliminating the tumor.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1038/s41598-018-25573-8,Medicine_easy_65,"""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor.",The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor.,"In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered,"" write the investigators. ""The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles.","In contrast, injection of free doxorubicin caused widespread organ damage, even when less amount was administered. The lack of toxic effect of nanoparticle loaded doxorubicin was associated with specific delivery of doxorubicin to the tumor. Furthermore, we observed excellent tumor accumulation of the nanoparticles.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1001/jama.2013.277165,Medicine_easy_66,Study anticoagulant was discontinued because of bleeding in 242 patients (4.7 percent) in the otamixaban group and in 95 patients (1.7 percent) in the UFH-plus-eptifibatide group.,Study anticoagulant was discontinued because of bleeding in 242 patients (4.7%) in the otamixaban group and in 95 patients (1.7%) in the UFH-pluseptifibatide group (P < .001).,"Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used. Study anticoagulant was discontinued because of bleeding in 242 patients (4.7 percent) in the otamixaban group and in 95 patients (1.7 percent) in the UFH-plus-eptifibatide group. ""Otamixaban did not reduce ischemic events compared with UFH plus eptifibatide but increased bleeding among patients with NSTE-ACS and a planned invasive strategy.","Otamixaban consistently increased all types of bleeding events, regardless of the severity or bleeding classification scheme used (Table 2 ; and eTable 4 in the Supplement), and without interaction across patient subsets, including demographics, previous treatment, risk scores, biomarkers or management (eFigure 3B and eFigure 4 in the Supplement). Study anticoagulant was discontinued because of bleeding in 242 patients (4.7%) in the otamixaban group and in 95 patients (1.7%) in the UFH-pluseptifibatide group (P < .001). Except for bleeding, there were no differences in the rate of adverse events or serious adverse events or liver-function abnormalities (eTable 5 in the Supplement).",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/09/130901153354.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13578-015-0003-4,Medicine_easy_69,"Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","We further found that PC increased H2S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts. LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts.","We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts. LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H 2 S against I/R induced myocardial damage in the aging hearts.",[5],Medicine,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1038/s41598-018-30933-5,Medicine_easy_73,"Individuals representing great green macaws did the best of all of the species studied in that all of them ""performed significantly above chance throughout all six test conditions, suggesting that they successfully weighed up between the two options to make the most advantageous choice.""","In summary, on a group level, the great green macaws were the only species in which most of the individuals performed significantly above chance throughout all six test conditions, suggesting that they successfully weighed up between the two options to make the most advantageous choice.","They did so regardless of the value of the immediate gain."" Individuals representing great green macaws did the best of all of the species studied in that all of them ""performed significantly above chance throughout all six test conditions, suggesting that they successfully weighed up between the two options to make the most advantageous choice."" It's interesting to ask about the ecological relevance of this study and how the results reflect what parrots have to do in the wild.","Five of 13 Goffin cockatoos selected their most preferred food over a tool that could be used to obtain the same food (an analogue to condition 6 in the present study). In summary, on a group level, the great green macaws were the only species in which most of the individuals performed significantly above chance throughout all six test conditions, suggesting that they successfully weighed up between the two options to make the most advantageous choice. These findings are in line with previous studies showing that cockatoos, a distantly related psittaciforme, also decide economically.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37046481434&p=1pl&v=1&x=hbAvZo2c40WZuNN_G5gurQ
10.1001/jamaneurol.2015.0475,Medicine_easy_74,"Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset.","Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset.","""We found an increased risk of neuropathy in patients with CD [celiac disease] that persists after CD diagnosis. Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset. Our findings suggest that screening could be beneficial in patients with neuropathy,"" researchers wrote in an article detailing their study.","We found an increased risk of neuropathy in patients with CD that persists after CD diagnosis. Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset. Our findings suggest that screening could be beneficial in patients with neuropathy.",[5],Medicine,train,5.0,news,http://www.techtimes.com/articles/52228/20150512/celiac-disease-linked-to-nerve-disease-in-neuropathy-patients-is-gluten-to-blame.htm
10.1001/jamaneurol.2017.4618,Medicine_easy_75,"The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2 percent and 90.2 percent, respectively.","The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2% (95% CI, 66.8%-83.7%) and 90.2% (95% CI, 86.8%-93.7%), respectively.","Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae. The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2 percent and 90.2 percent, respectively. In addition, the positive and negative predictive values were 73.1 percent and 91.2 percent, respectively.","Multivariable logistic regression analysis indicated that the presence of acute brain lesions was independently associated with development of delayed neurological sequelae (adjusted odds ratio, 13.93; 95% CI, 7.16-27.11; P < .001). The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2% (95% CI, 66.8%-83.7%) and 90.2% (95% CI, 86.8%-93.7%), respectively. In addition, the positive and negative predictive values were 73.1% (95% CI, 64.6%-81.6%) and 91.2% (95% CI, 87.9%-94.5%), respectively.",[5],Medicine,train,5.0,news,http://www.diagnosticimaging.com/article/imaging-may-identify-potential-delayed-neurological-sequelae-after-carbon-monoxide-poisoning
10.1002/ijc.28956,Medicine_easy_76,"""However the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas were already more than 1 mm thick when diagnosed,"" Professor Green said.","However, the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas are already >1 mm thick when diagnosed.","As expected in the state's sunny climate, young Queenslanders are still up to five times more likely to be diagnosed with melanoma than young people in the US or Europe. ""However the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas were already more than 1 mm thick when diagnosed,"" Professor Green said. ""This generally favourable outcome is likely due, in large part, to early detection, resulting from increased skin cancer awareness.""","In conclusion, our study shows that the incidence rates of invasive melanoma are relatively high in adolescents and young adults in Queensland compared with other white populations as expected due to the state's sunny climate. However, the risk of death due to melanoma in this age group is generally low except among a small proportion of cases whose melanomas are already >1 mm thick when diagnosed. We have also shown that the incidence of thin invasive melanoma has declined since the mid-to late 1990s among young people who have been exposed to Queensland's primary prevention and early detection programs since birth.",[5],Medicine,train,5.0,news,http://www.healthcanal.com/cancers/skin-cancer/51127-melanoma-rates-dropping-in-young-queenslanders.html
10.1186/s13578-015-0003-4,Medicine_easy_77,These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.,These findings suggested that H 2 S might be a novel target for the treatment of aging cardiovascular diseases.,"LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts. These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.","In conclusion, these results demonstrate that exogenous H 2 S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3β pathway in the aging rat hearts. These findings suggested that H 2 S might be a novel target for the treatment of aging cardiovascular diseases. PC can be evoked by applying cycles of brief intermittent interruption of blood flow to the myocardium at the immediate onset of reperfusion after a prolonged period of ischemia.",[5],Medicine,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1001/jama.2018.14619,Medicine_easy_78,"""Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events,"" the authors write.",Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events.,"At five years, bariatric surgery correlated with a lower composite incidence of macrovascular events (2.1 versus 4.3 percent; hazard ratio, 0.60; 95 percent confidence interval, 0.42 to 0.86) and lower incidence of coronary artery disease (1.6 versus 2.8 percent; hazard ratio, 0.64; 95 percent confidence interval, 0.42 to 0.99). At five years, the incidence of cerebrovascular disease did not differ significantly between the groups (0.7 versus 1.7 percent; hazard ratio, 0.69; 95 percent confidence interval, 0.38 to 1.25). ""Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events,"" the authors write.","The findings require confirmation in randomized clinical trials. Health care professionals should engage patients with severe obesity and type 2 diabetes in a shared decision making conversation about the potential role of bariatric surgery in the prevention of macrovascular events. [5] [6] [7] [8] [9] In comparison, patients who have bariatric surgery have better glycemic control and greater macrovascular risk factor reduction than those who get both intensive lifestyle and medical treatment combined.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37411788291&p=1pl&v=1&x=z91QmlOw-rhPBgdbiO_iaQ
10.1001/jamaneurol.2015.0475,Medicine_easy_79,"Our findings suggest that screening could be beneficial in patients with neuropathy,"" researchers wrote in an article detailing their study.",Our findings suggest that screening could be beneficial in patients with neuropathy.,"""We found an increased risk of neuropathy in patients with CD [celiac disease] that persists after CD diagnosis. Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset. Our findings suggest that screening could be beneficial in patients with neuropathy,"" researchers wrote in an article detailing their study.","We found an increased risk of neuropathy in patients with CD that persists after CD diagnosis. Although absolute risks for neuropathy are low, CD is a potentially treatable condition with a young age of onset. Our findings suggest that screening could be beneficial in patients with neuropathy.",[5],Medicine,train,5.0,news,http://www.techtimes.com/articles/52228/20150512/celiac-disease-linked-to-nerve-disease-in-neuropathy-patients-is-gluten-to-blame.htm
10.1111/cdev.12370,Medicine_easy_80,"In turn, these new insights were associated with less emotional distress.","This process could be especially useful in regulating emotions during adolescence, a period characterized by more powerful and frequent negative emotional experiences than any other ).","They were also less likely to continue to blame the other person involved in the event (though not less likely to forgive him or her). In turn, these new insights were associated with less emotional distress. ""In fact, they were dealing with them in a more adaptive way.""","These findings highlight the role that self-distancing plays in fostering adaptive self-reflection in adolescence, and begin to elucidate the role that development plays in enhancing the benefits of engaging in this process. This process could be especially useful in regulating emotions during adolescence, a period characterized by more powerful and frequent negative emotional experiences than any other ). Analyzing negative experiences from a self-distanced perspective led participants to focus less on recounting the emotional details of the event and more on reconstruing it in ways that promoted insight and closure.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150415092801.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1534/genetics.116.197285,Medicine_easy_81,"In only a handful of generations you go from having almost no copies of the mutation in the population to it being 'fixed' so every individual in the population has it -- at least that was the simple theory.""","For example, when the driver has a dominant fitness cost of s dd = 0.1, resistance alleles would have to be present at .","""That might include the CRISPR/Cas9 machinery but also a new gene that provides resistance to dengue fever in the mosquito, for example, so the two spread together. In only a handful of generations you go from having almost no copies of the mutation in the population to it being 'fixed' so every individual in the population has it -- at least that was the simple theory."" Yet, faced with the new and sophisticated CRISPR/Cas9 method of gene drive, nature is still likely to fight back to resist the mutation successfully, Unckless said.","2). For example, when the driver has a dominant fitness cost of s dd = 0.1, resistance alleles would have to be present at . Note that we would expect this to be the case in scenarios with δ > 10 -3 (SI section 3.1).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1001/jama.2018.7028,Medicine_easy_82,It goes without saying humans do not face the same stressors as those who called earth home millions of years ago.,"Findings from the present study demonstrated that not only patients with PTSD, but also individuals with other and more common stress-related disorders, experienced considerably increased relative risk of autoimmune disease.",The chemicals released by your brain that make you nervous around your crush are the same ones that alarmed your archaic ancestors of possible predators. It goes without saying humans do not face the same stressors as those who called earth home millions of years ago. The findings were alarming.,"22 These findings gain support from previous studies of male Vietnam War veterans 10,11 linking self-reported symptoms of PTSD to higher prevalence of a few selected autoimmune diseases. Findings from the present study demonstrated that not only patients with PTSD, but also individuals with other and more common stress-related disorders, experienced considerably increased relative risk of autoimmune disease. Although the present findings are of etiologic importance, the relatively modest differences in incidence rates of autoimmune disease between the exposed and unexposed individuals (9.1 and 6.0 per 1000 person-years, respectively) do not provide direct evidence for altered clinical management or monitoring of persons with stress-related disorders.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34371117916&p=1pl&v=1&x=bgKj_4ZxA1hgbO_2itXByg
10.1016/j.cell.2018.04.038,Medicine_easy_85,TRAP plays a crucial role in adding on small pieces of DNA to the ends of chromosomes to keep them from shortening every time cells divide.,Direct telomerase activity assays with dGTP on the purified telomerase confirmed that the DNA binds and a single dG is added in the expected register (Figure S1) .,"When telomerase is not active, each time the cells divide, the telomeres get shorter. TRAP plays a crucial role in adding on small pieces of DNA to the ends of chromosomes to keep them from shortening every time cells divide. The researchers report for the first time the structure, shape and significance of TRAP, and the region with which it interacts.","The structure reveals how the sstDNA and TERT-specific domains, including a previously uncharacterized domain, interact with TER and each other to regulate the catalytic cycle and how telomere-interacting proteins bind to TERT, and it explains decades of biochemical and mutagenesis data on ciliate and human telomerase. Direct telomerase activity assays with dGTP on the purified telomerase confirmed that the DNA binds and a single dG is added in the expected register (Figure S1) . As observed for DNA-free telomerase, sstDNA-bound telomerase is conformationally heterogeneous (see Method Details).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1016/j.cell.2015.07.058,Medicine_easy_86,"When it comes to defending against DNA viruses, however, the Salk team found something interesting: the cell's response system begins the same way (with MRN detecting either DNA or viral breaks) but never progresses to the global alarm signal in the case of the virus.","However, similar to SAECs, the levels of virus genomes are 10 4 times higher in WT versus DE1B-55K/DE4-ORF3-infected A549 cells ( Figure 2B ).","""This response prevents replication so the cell doesn't pass on a break."" When it comes to defending against DNA viruses, however, the Salk team found something interesting: the cell's response system begins the same way (with MRN detecting either DNA or viral breaks) but never progresses to the global alarm signal in the case of the virus. The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell.","Adenovirus replication is accelerated by about 12 hr in A549 cells. However, similar to SAECs, the levels of virus genomes are 10 4 times higher in WT versus DE1B-55K/DE4-ORF3-infected A549 cells ( Figure 2B ). In WT-virus-infected cells, neither MR knockdown nor Mirin prevents the global phosphorylation of DDR substrates ( Figure 2C ).",[1],Medicine,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1016/j.bodyim.2016.09.005,Medicine_easy_87,This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better.,This condition provided no feedback about the movement of Barbie's body.,This was not the first time researchers claim Barbie dolls affect young girls' body image. This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better. The researchers suggested parents should emphasize and discuss what entails having a healthy body with their little girls so that they can develop good body image concepts.,"This condition also enabled a comparison to the findings of . This condition provided no feedback about the movement of Barbie's body. "", similar to the measure used by with early school-aged children.",[1],Medicine,train,1.0,news,http://www.parentherald.com/articles/97873/20170130/barbie-dolls-harm-little-girls-body-image-experts-advise-parents.htm
10.1186/2045-5380-3-19,Medicine_easy_88,It works by heightening CNS connections to control hyperactivity and impulses.,"Taken together, this review of the preclinical research regarding the role of the eCB system in the regulation of stress and emotional behavior creates a compelling argument that eCB signaling acts to constrain activation of the stress response, and the ensuing neuroendocrine and behavioral responses to stress.","As such, the potential CBD shows as the most effective natural alternative to Adderall is very significant. It works by heightening CNS connections to control hyperactivity and impulses. This, in turn, helps improve focus and attention in those with ADHD.","Possible mechanisms of action of eCB augmentation in the mitigation of stress-induced behavioral dysregulation include modulation of hippocampal neurogenesis and amygdala dendritic hypertrophy . Taken together, this review of the preclinical research regarding the role of the eCB system in the regulation of stress and emotional behavior creates a compelling argument that eCB signaling acts to constrain activation of the stress response, and the ensuing neuroendocrine and behavioral responses to stress. In response to stress, particularly stress of high emotional load or repeated exposure to a common stressor, there is a mobilization of 2-AG, which seems to be important for restricting the magnitude of the stress response and aiding in normative recovery to pre-stress levels of functioning.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1111/all.13333,Medicine_easy_89,The study suggested that the seasonal flu vaccine may not be effective in preventing hospitalization due to influenza community-acquired pneumonia.,"The success of vaccination programs was affected by complex factors such as the nature of healthcare provision (eg, free care or insurance-based), education levels, and cultural acceptance of the vaccine.","Advertisement

Follow eMaxHealth on YouTube, Twitter and Facebook Please, click to subscribe to our Youtube Channel to be notified about upcoming health and food tips. The study suggested that the seasonal flu vaccine may not be effective in preventing hospitalization due to influenza community-acquired pneumonia. Important implication also says that while vaccines may be a primary prevention strategy they are not 100% effective.","Pediatricians were more likely than family physicians to routinely recommend influenza vaccination to children with asthma (adjusted OR 3.49, 95% CI 1.68-7.22), with decisions also being made depending on asthma phenotype (ie, intermittent vs. persistent). The success of vaccination programs was affected by complex factors such as the nature of healthcare provision (eg, free care or insurance-based), education levels, and cultural acceptance of the vaccine. Therefore, national health surveys with information on vaccination status linked with medical and socio-demographic details (such as that of Spain with data spanning more than 2 decades ) can aid in assessing the impact of influenza vaccination, at population level.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37849057616&p=1pl&v=1&x=xt4Zpy97jdfgJxOWwQtwhA
10.1186/s12916-017-0986-2,Medicine_easy_90,"""Older adults are a diverse group of patients whose risk of postoperative complications is not solely defined by their age, co-morbidities (multiple health problems) or the type of surgical procedure they receive,"" Watt said.","Among patients undergoing cardiac surgery, the pooled incidence of mortality was 5.21% (4.00-6.75%, 6 studies, I 2 = 60.8%, NNF = 20).","""The fact that age and ASA status were not risk factors for postoperative complications is somewhat surprising because these are the factors a clinician would typically look at when assessing a patient's risk of developing complications after surgery,"" study author Dr. Jennifer Watt said in a hospital news release. ""Older adults are a diverse group of patients whose risk of postoperative complications is not solely defined by their age, co-morbidities (multiple health problems) or the type of surgical procedure they receive,"" Watt said. ""This study highlights how common postoperative complications are among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults who may be at risk,"" she said.","The pooled incidence of mortality was 4.58% (95% CI 3.67-5.71%, 11 studies, I 2 = 46.30%, NNF = 21) [1-3, 25, 30, 32, 51, 53, 55-57] . Among patients undergoing cardiac surgery, the pooled incidence of mortality was 5.21% (4.00-6.75%, 6 studies, I 2 = 60.8%, NNF = 20). Only the effects of publication year could be explored in a meta-regression because there were not enough studies to explore the effects of type of surgery or mean age of patients on the pooled incidence of mortality.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33000673455&p=1pl&v=1&x=ZUA80X35mG1U_VnPyqM0hw
10.1001/jamapsychiatry.2018.1941,Medicine_easy_91,"Getting to the bottom of exactly what's going on will require more research, but one of the more promising avenues to explore is the role of the lateral orbitofrontal cortex.","Key areas shown include the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the anterior and posterior cingulate cortices, and the insula.","While this particular study found strong neural connections in the association of depressive problems with poor sleep quality, rather than the other way around, in general the effects can work both ways. Getting to the bottom of exactly what's going on will require more research, but one of the more promising avenues to explore is the role of the lateral orbitofrontal cortex. Specifically targeting this part of the brain with treatments, the study authors say, could lead to some major progress being made.","With the Depressive Problems Score eFigure 4 and eTable 2 in the Supplement show correlations between the functional connectivities across the whole brain and the Depressive Problems score. Key areas shown include the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the anterior and posterior cingulate cortices, and the insula. If the 92 participants who had ever been diagnosed with depression were removed from this analysis, the correlations of some of these areas with the Depressive Problems score were still significant, including the anterior cingulate gyrus and middle frontal gyrus (middle frontal gyrus with right anterior cingulate cortex: r = 0.115; P = .001; left cuneus with left superior frontal gyrus, dorsolateral: r = −0.109; P = .002; right inferior parietal gyrus, excluding supramarginal and angular gyri with left middle cingulate and paracingulate gyri: r = 0.059; P = .01; right middle frontal gyrus with left anterior cingulate cortex: r = 0.059; P = .01; left postcentral gyrus with left inferior temporal lobe: r = 0.059; P = .01; eTable 2 in the Supplement).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1038/s41467-018-08278-4,Medicine_easy_92,Die Wissenschaftler konnten das Wachstum in geschadigten oder amputierten Gliedmassen von Mausen mit nur zwei Proteinen kunstlich stimulieren: BMP2 und BMP9.,"In cavity-forming digits, the nodule is not next to the BMP9 bead and BrdU-labeled chondrocytes are not present, indicating that BMP9 does not stimulate chondrocyte proliferation (Supplementary Fig.","Die Wissenschaftler konnten das Wachstum in geschadigten oder amputierten Gliedmassen von Mausen mit nur zwei Proteinen kunstlich stimulieren: BMP2 und BMP9. Das konnte Sie auch interessieren

Trotz Regeln floss bei den brutalen Ritterspielen viel Blut

Die Nasa hat auf dem Neptun einen ,,dunklen Wirbelsturm"" entdeckt, der 20 Prozent der Erdoberflache schlucken wurde

Die Regeneration von Knochen wurde auch fruher erreicht, aber ohne das zusatzliche Protein wurden die Knochen zum Beispiel nach einer Fraktur zusammenwachsen, anstatt Gelenk- und Knorpelgewebe zu vergrossern. Zwar ist die Studie nur ein kleiner Schritt, sie konnte aber zu einem grossem Fortschritt bei der Behandlung von Erkrankungen wie Arthrose fuhren.","These data indicate that BMP9 stimulates the aggregation and differentiation of chondrocytes but their progression to hypertrophic chondrocytes is delayed compared to BMP2-treated digits . In cavity-forming digits, the nodule is not next to the BMP9 bead and BrdU-labeled chondrocytes are not present, indicating that BMP9 does not stimulate chondrocyte proliferation (Supplementary Fig. The absence of proliferating chondrocytes and delayed hypertrophic differentiation distinguishes the BMP9 response from BMP2 stimulation of endochondral ossification .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38488446029&p=1pl&v=1&x=pEPzQn-OGtRw5F4FBoLIWA
10.1016/j.neuron.2017.06.028,Medicine_easy_93,The findings are published in the journal Neuron and have the potential to reveal new therapeutic strategies for neurological and psychiatric disorders.,"In absence of BCAN, GluA1 fails to cluster in postsynaptic densities and this seems to cause a loss of excitatory synaptic contacts onto PV+ interneurons.","The findings are published in the journal Neuron and have the potential to reveal new therapeutic strategies for neurological and psychiatric disorders. As such, unravelling key molecular players in this form of plasticity may pave the way for new treatments. The researchers also found that this protein shapes the intrinsic properties of PV+ interneurons and sculpts their connections to other neurons.","BCAN affects excitatory synaptic differentiation, at least in part by modulating the levels of GluA1 receptor at the synapse. In absence of BCAN, GluA1 fails to cluster in postsynaptic densities and this seems to cause a loss of excitatory synaptic contacts onto PV+ interneurons. Since the specific depletion of GluA1 from PV+ cells causes a similar phenotype, it is unlikely that the reduction in GluA1 observed in Bcan mutants is due to the loss of synapses by a GluA1-independent mechanism.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1016/j.cell.2016.09.056,Medicine_easy_94,"For example, the work could assist researchers who are taking aim at the tetraspanin CD37 in clinical trials to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma.","However, it now seems at least equally likely that other factors are more responsible for the creation of tetraspanin-enriched microdomains than direct interactions between tetraspanins themselves.","Illuminating dark matter

In addition to helping researchers understand and potentially target CD81, the discovery may illuminate other tetraspanins and their disease connections because they likely share CD81's structure, the researchers say. For example, the work could assist researchers who are taking aim at the tetraspanin CD37 in clinical trials to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma. Even if clinical applications don't pan out, though, the work excites Blacklow because it represents one of the last remaining opportunities to illuminate ""dark matter"" in transmembrane protein biology, he said.","An important caveat from our structure is the fact that four intracellular cysteine residues were mutated to prevent disulfide crosslinking during purification. However, it now seems at least equally likely that other factors are more responsible for the creation of tetraspanin-enriched microdomains than direct interactions between tetraspanins themselves. Our results reveal that CD81 binds cholesterol and that E219 is an important residue in the binding pocket, offering a potential mechanism for how tetraspanins might detect cholesterol or other membrane lipids (whereas CD81 and tspan10 both possess a polar residue in this position, most other tetraspanins have a polar residue one helical turn earlier, with other cholesterol-interacting residues highly conserved throughout evolution).",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ay74vlkGcfw/
10.1111/cdev.12250,Medicine_easy_95,"Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse.","Although no measures of pubertal status were available in this study, by the ages of 13-15, the period during which pseudomature behavior was observed, the vast majority of teens are well into puberty.","In fact, researchers discovered that by around 22, most school celebrities had been denoted to just your average Joe. Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse. ""The student who was popular and was running with the fast crowd isn't doing as great later on.""","Second, one question that might be asked regarding these findings is how they relate to the pubertal status of early adolescents, which has been inconsistently linked to delinquent and romantic behavior . Although no measures of pubertal status were available in this study, by the ages of 13-15, the period during which pseudomature behavior was observed, the vast majority of teens are well into puberty. This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed.",[1],Medicine,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1186/gb-2013-14-7-r73,Medicine_easy_97,"Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients.",All this begs the question of what such huge transcripts could be doing.,"Researchers found that some of these vlincRNAs are co-opted by cancer-associated transcriptional programs. Importantly, removal of these RNAs causes the death of cancer cells providing a clear direction for the development of therapeutics and better diagnostics for cancer patients. VlincRNAs may contribute to the regulation of gene expression in the nucleus of the cell.","These findings should signal re-evaluation of the results of GWAS studies where disease-associated variants are often found outside of known genes. All this begs the question of what such huge transcripts could be doing. While some of these vlincRNA regions could possibly produce spliced protein-coding transcripts, the long un-spliced versions of these RNAs would very unlikely code for proteins, especially considering that, for the most part, they localize to the nucleus (data not shown).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1534/genetics.116.197285,Medicine_easy_98,"""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said.","In heterozygotes, the driver can cleave the sister chromosome at the target site and insert itself via homology-directed repair, converting heterozygotes for the driver construct into homozygotes (Fig.","They show nature still has the edge over scientists hoping to solve human problems with GM organisms. ""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said. We argue resistance could be thought of as a good thing -- if we know it's going to evolve, we can plan around it, and understand a gene drive is a temporary solution.","This study highlights the need for careful modeling of CGD prior to the actual release of a driver construct into the wild. In heterozygotes, the driver can cleave the sister chromosome at the target site and insert itself via homology-directed repair, converting heterozygotes for the driver construct into homozygotes (Fig. In addition, arbitrary genetic segments can be included in the construct that will be transmitted alongside the driver.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1098/rsos.171474,Medicine_easy_99,Halo didn't cause Sandy Hook.,"This flexibility, described as part of the 'garden of forking paths problem' increases the chance of false-positive results and serves to reduce our confidence in the inferences linking gaming to aggression .",Call of Duty didn't cause Parkland. Halo didn't cause Sandy Hook. Doom didn't cause Columbine.,"First, there is a noticeable degree of flexibility in how violent game play is operationalized in survey studies. This flexibility, described as part of the 'garden of forking paths problem' increases the chance of false-positive results and serves to reduce our confidence in the inferences linking gaming to aggression . Said differently, this work depends on children and young people accurately reporting on their video game play, the level of violent content present in this play and their own trait-or state-level aggression (for an exception, see ).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39876854667&p=1pl&v=1&x=20068Ts8P0DG-mROX7fxQA
10.1098/rsos.171474,Medicine_easy_100,"excessive bullying, workplace intimidation); 16% had engaged in intimate partner violence, and 11% had engaged in stalking-related conduct.",We argue that this study speaks to the key question of whether adolescents' violent video game play has a measurable effect on real-world aggressive behaviour.,"For example the FBI report referenced above finds that while the 63 active shooters examined in the study couldn't be linked based on demographics alone:

62% of the shooters had a history of acting in an abusive, harassing, or oppressive way (e.g. excessive bullying, workplace intimidation); 16% had engaged in intimate partner violence, and 11% had engaged in stalking-related conduct. According to the FBI report, only 25% of active shooters between 2000 and 2013 had ever been diagnosed with mental illness.","This pattern of findings further suggests that links reported in the literature might be influenced by publication bias, selective reporting, or an artefact of unobserved or hidden moderators, as has been previously suspected . We argue that this study speaks to the key question of whether adolescents' violent video game play has a measurable effect on real-world aggressive behaviour. On the basis of our evidence, the answer is no.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882736616&p=1pl&v=1&x=QLA1HMQhScCizGL1drmq5A
10.1038/s41467-018-06824-8,Medicine_easy_101,"The social bees' gene was about 15 times as active as that of the solitary bees, her team reports today in Nature Communications , making it a strong candidate for the switch to sociality.","We estimated the nucleotide diversity per site (π) to be 0.002, and we did not find differences in genetic diversity among social forms (Supplementary Table 1 ; two-sample t-test; t 4 = −0.961, p = 0.391).","""It seemed a good place to start."" The social bees' gene was about 15 times as active as that of the solitary bees, her team reports today in Nature Communications , making it a strong candidate for the switch to sociality. These findings are in line with syntaxin function in other animals, Kocher says.","Whole-genome resequencing data identified a total of 2,6,960 genetic variants among 143 individuals of L. albipes that passed our quality filters (see Methods; Supplementary Data 1). We estimated the nucleotide diversity per site (π) to be 0.002, and we did not find differences in genetic diversity among social forms (Supplementary Table 1 ; two-sample t-test; t 4 = −0.961, p = 0.391). As in honey bees , LD decays rapidly with physical distance:",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37425745606&p=1pl&v=1&x=BF9poLDtNwHfjOufQy7mMA
10.1001/jamapsychiatry.2013.4081,Medicine_easy_102,The study adds to a growing body of research focused on the specific effects of parental age.,"Considering the broadest category of any psychiatric diagnosis (ICD-10-DCR codes F00-F99) as the outcome of interest, the offspring of the youngest mothers were at the highest risk for any mental disorders.","While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29. The study adds to a growing body of research focused on the specific effects of parental age. But it's not the first to find that an older father might make you more prone to psychiatric illness.","Overall, the cohort was followed up for 42.7 million person-years, during which 218 441 members of the cohort had their first psychiatric contact for any psychiatric disorder. Considering the broadest category of any psychiatric diagnosis (ICD-10-DCR codes F00-F99) as the outcome of interest, the offspring of the youngest mothers were at the highest risk for any mental disorders. Compared with the offspring of mothers aged 25 to 29 years, the offspring of mothers aged 12 to 19 years had a 51% increased risk of having a mental disorder (IRR, 1.51 [95% CI, 1.48-1.54]).",[1],Medicine,train,1.0,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1001/jamaoncol.2018.3701,Medicine_easy_103,"""This is a scenario where care is probably not beneficial and also costly--and we are putting a dollar figure on just how costly this is.""","CONCLUSIONS AND RELEVANCE There is substantial cost to the Medicare program associated with the diagnosis and treatment of localized prostate cancer among elderly men in the United States, despite the fact that these men are unlikely to die of prostate cancer.","The study also showed that of the total, $451 million was spent on men who were diagnosed with prostate cancer that is graded with a Gleason score of 6, which is considered to be low-grade disease and is best managed using active surveillance rather than aggressive treatment. ""This is a scenario where care is probably not beneficial and also costly--and we are putting a dollar figure on just how costly this is."" Recommended Screening

The researchers said there is a wide recognition that screening for prostate cancer should stop in men at age 70.","IMPORTANCE Localized prostate cancer diagnosis and treatment among elderly men who are not likely to benefit represents a potential source of low-value health care services. CONCLUSIONS AND RELEVANCE There is substantial cost to the Medicare program associated with the diagnosis and treatment of localized prostate cancer among elderly men in the United States, despite the fact that these men are unlikely to die of prostate cancer. The majority of costs are related to treatment.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37161484598&p=1pl&v=1&x=LLy33mp4g8e_fImU9SDVlg
10.1155/2013/783698,Medicine_easy_104,"The study's findings, published online in the open-access journal BioMed Research International, raise important questions about the direction of current research efforts, health resource allocation and the diagnosis and treatment of infected children in India and around the world, the researchers say.",Four of 7 (57%) children with culture-confirmed TB harbored drug-resistant (DR) strains of whom 2 (50%) were multi-DR (MDR).,"The study's findings, published online in the open-access journal BioMed Research International, raise important questions about the direction of current research efforts, health resource allocation and the diagnosis and treatment of infected children in India and around the world, the researchers say. ""Pediatric TB is a decidedly different disease from adult TB, and our findings support the notion that childhood infections may require different prevention, diagnostic, containment and treatment tools,"" says lead investigator Sanjay Jain, M.D., an infectious disease specialist at the Johns Hopkins Children's Center. In nearly half of those (12) the disease had spread beyond the lungs.","Extrapulmonary disease was noted in 46%, which was predominantly meningeal. Four of 7 (57%) children with culture-confirmed TB harbored drug-resistant (DR) strains of whom 2 (50%) were multi-DR (MDR). In adjusted analyses, HIV infection, positive TST, and exposure to household smoke were found to be significantly associated with children with TB ( ≤ 0.04).",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/johns-hopkins-study-highlights-challenges-of-tuberculosis-in-children
10.1126/scitranslmed.aan2415,Medicine_easy_105,They found none of the cancer-derived mutations among blood samples of 44 healthy individuals.,"In principle, analysis of ctDNA has the advantage of identifying alterations that are specific to the tumor.","Among 45 breast cancer patients, the test spotted cancer-derived mutations in two of three (67 percent) patients with stage I disease, 17 of 29 (59 percent) with stage II disease and six of 13 (46 percent) with stage III cancers. They found none of the cancer-derived mutations among blood samples of 44 healthy individuals. Despite these initial promising results for early detection, the blood test needs to be validated in studies of much larger numbers of people, say the scientists.","These analyses provide a broadly applicable approach for noninvasive detection of early-stage tumors that may be useful for screening and management of patients with cancer. In principle, analysis of ctDNA has the advantage of identifying alterations that are specific to the tumor. Overall, these analyses provide information on the potential use and limitations of large-scale mutation-based measurements of ctDNA for early diagnosis in common cancers.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/scientists-develop-blood-test-that-spots-tumor-derived-dna-in-people-with-early-stage-cancers/
10.1186/s40168-015-0071-z,Medicine_easy_106,"""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said.",The ecological phenomena of alternative stable community states may help explain this bimodal distribution in the infant gut.,"advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces. ""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said. Maternal secretor status is likely only one of the many factors that influence the infant gut microbiota, Lewis said.","Using this cutoff, our data also agree with the growing consensus that the establishment of bifidobacteria can happen in many infants in the first week of life . The ecological phenomena of alternative stable community states may help explain this bimodal distribution in the infant gut. Perhaps once a certain threshold of bifidobacteria/gram feces is reached the amount of SCFA and lactate produced alters the pH of the gut lumen, overcoming the buffering capacity of the luminal contents.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41598-019-40955-2,Medicine_easy_107,"""So far, we plan to continue our 'seaweed project' in Okinawa,"" said Nishitsuji.","Although taxonomic classification of these brown algae should include morphological and life cycle data, the results appear to support the order Chordariales, including N. decipiens and C. okamuranus.","The Unit plans to continue sequencing samples from the Cooperative, but someday, they hope to extend their research even further. ""So far, we plan to continue our 'seaweed project' in Okinawa,"" said Nishitsuji. ""If possible, we would like to expand it to cover all of Japan.""","First, molecular phylogeny using 32 mitochondrial genes showed that N. decipiens and C. okamuranus share a more recent common ancestor. Although taxonomic classification of these brown algae should include morphological and life cycle data, the results appear to support the order Chordariales, including N. decipiens and C. okamuranus. An intimate relationship between N. decipiens and C. okamuranus can also be deduced from their morphology.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38763824360&p=1pl&v=1&x=EwLVh9xrW10mzhFmqvXNkA
10.1016/j.jpeds.2017.10.028,Medicine_easy_108,Temple hopes his research in identifying possible risk factors for domestic abuse may be applied to develop better intervention for children subjected to corporal punishment as they age.,"Third, consistent with extant literature, female subjects were more likely to perpetrate teen dating violence than their male counterparts.","Werner-Wilson emphasized that research shows not all corporal punishment is negative, and if it is done under certain parameters, such as being conducted soon after the punishable act and being done without a strong emotional reaction from the parent, the results can be positive. Temple hopes his research in identifying possible risk factors for domestic abuse may be applied to develop better intervention for children subjected to corporal punishment as they age. ""It's difficult to change our structure, our culture, and parents' behavior, but even with all that if we can affect kids through prevention programs than that would certainly be a step in the right direction,"" added Temple.","Second, in contrast to past research, no differences in corporal punishment were found when stratified by demographic characteristics. Third, consistent with extant literature, female subjects were more likely to perpetrate teen dating violence than their male counterparts. Notably, this latter finding refers only to acts of violence and not frequency or severity, which is important, given research showing that female subjects may suffer more long-term negative physical and psychosocial consequences of teen dating violence.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1073/pnas.1408439111,Medicine_easy_110,"Accounting for variables, the team managed to create an accurate model of population density, essentially replacing the census.","Although these previously published estimates were obtained based on the number of calls or users per MP tower, rather than on the density of calls or users in a tower's covering area, similar values were expected in our analysis.","Scientists can utilize this widespread cell phone use to pinpoint cell phone tower activity, calculating the cell phone use to estimate local population density -- even in nations where a census is not taken or strongly regulated. ""This is the first time people have provided statistical evidence that population data produced from cellphone records are of really good quality,"" said Renaud Lambiotte, an applied mathematician at the University of Namur in Belgium. Accounting for variables, the team managed to create an accurate model of population density, essentially replacing the census.","As shown in SI Appendix, section A.3, a combination of both methods further improved the accuracy of the population mapping, highlighting the complementarity of the two approaches. Although these previously published estimates were obtained based on the number of calls or users per MP tower, rather than on the density of calls or users in a tower's covering area, similar values were expected in our analysis. By using a standard cross-validation procedure in Portugal, best-fit estimates of 62.95 ± 2.48 for α and 0.803 ± 0.015 for β were found, whereas these estimations became 69.11 ± 10.49 for α and 0.767 ± 0.055 for β when using a spatially stratified crossvalidation procedure (SI Appendix, section B.2).",[1],Medicine,train,1.0,news,http://www.inquisitr.com/1569497/scientists-have-discovered-a-way-to-take-a-census-with-cell-phones/
10.1038/ncomms4632,Medicine_easy_111,"They found that the faster the nanomotor rotated, the faster it released the drugs.",No clear wear was found on the nanowire rotor (Fig.,"In the near future, the Cockrell School researchers believe their nanomotors could provide a new approach to controlled biochemical drug delivery to live cells. They found that the faster the nanomotor rotated, the faster it released the drugs. ""We were able to establish and control the molecule release rate by mechanical rotation, which means our nanomotor is the first of its kind for controlling the release of drugs from the surface of nanoparticles,"" Fan said.","7c reveals the final Au thickness of B15 nm, reduced from its original thickness of 40 nm (Fig. No clear wear was found on the nanowire rotor (Fig. 7c) , which can be attributed to the fact that Au (Vickers hardness: 216 MPa) is much softer than Ni (Vickers hardness: 638 MPa).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.2337/dc13-1904,Medicine_easy_112,Cameron and his team found that 20 to 30 percent of children newly diagnosed with type 1 diabetes had DKA.,"2E) and trended lower at 6 months compared with the non-DKA group (F = 5.80, P = 0.02).","Symptoms tended to develop over time, raising a big concern for parents who might not notice any differences in their child right away. Cameron and his team found that 20 to 30 percent of children newly diagnosed with type 1 diabetes had DKA. ""DKA still kills people, so we need to do better.","Gray matter MD in the frontal lobes decreased over 6 months with DKA (F = 50.23, P , 0.001) (Fig. 2E) and trended lower at 6 months compared with the non-DKA group (F = 5.80, P = 0.02). For spectroscopy, frontal gray matter NAA levels were lower at baseline in the DKA group (F = 8.73, P = 0.005) (Fig.",[1],Medicine,train,1.0,news,http://www.medicaldaily.com/type-1-diabetes-diagnosis-may-come-brain-changes-kids-including-memory-loss-284362
10.1088/1741-2552/aabc9b,Medicine_easy_113,"Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation.",In both patients there were energy savings without worsening of clinical symptoms.,"Doctors saw and patients noticed no differences in the improvement in movement under adaptive stimulation versus constant, open loop stimulation set manually by the researchers. Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","We have demonstrated the feasibility of adaptive DBS using a cortical detector sensitive to dyskinesia in two patients. In both patients there were energy savings without worsening of clinical symptoms. This strategy requires further testing in a chronic ambulatory setting, and may be useful in PD patients who are motor fluctuators and experience severe dyskinesia alternating with marked bradykinesia .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1088/1741-2552/aabc9b,Medicine_easy_114,"The new method described in this study is adaptive, so that the stimulation delivered is responsive in real time to signals received from the patient's brain.",The study was registered at ClinicalTrials.gov (NCT0193296).,"""The novel approach taken in this small-scale feasibility study may be an important first step in developing a more refined or personalized way for doctors to reduce the problems patients with Parkinson's disease face every day,"" said Nick B. Langhals, Ph.D., program director at NINDS and team lead for the BRAIN Initiative. The new method described in this study is adaptive, so that the stimulation delivered is responsive in real time to signals received from the patient's brain. The device differs from traditional ones in that it can both monitor and modulate brain activity.","Since this signature of dyskinesia is not disrupted by voluntary movement and occurs in a predictable frequency range, it is a promising control signal for adaptive DBS. The study was registered at ClinicalTrials.gov (NCT0193296). Because Activa PC+S was only implanted unilaterally, adaptive DBS was delivered only on one side.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1098/rsos.171474,Medicine_easy_115,"The registered study approach is a safe-guard against this,"" says Przybylski.","In fact, we observed at least three such correlations ranging in size from when considering uncorrected models using variables we did not hypothesize would be correlated with aggressive behaviour.","A cherry-picked result can add undue weight to the moral panic surrounding video games. The registered study approach is a safe-guard against this,"" says Przybylski. While no correlation was found between playing video games and aggressive behavior in teenagers, the researchers emphasize that this does not mean that some mechanics and situations in gaming do not provoke angry feelings or reactions in players.","Further, this is not to say that we could rule out a correlation between every operationalization of gaming and every measure of adolescents' violent behaviour. In fact, we observed at least three such correlations ranging in size from when considering uncorrected models using variables we did not hypothesize would be correlated with aggressive behaviour. For example, our positive control check question, a simple 5-point Likert scale that asked participants to rate their own intensity of engagement with games happened to be positively correlated (r ¼ 0.25) to aggressive behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38630667262&p=1pl&v=1&x=eg7bkQTzSVqLm5ru549FjQ
10.1111/cdev.12250,Medicine_easy_118,"""We suspect they may have then engaged in more and more extreme behaviors trying to gain peer approval,"" Allen said.","This constellation will be linked to greater peer popularity in the short term, but this link will fade as adolescence progresses and peers mature.","And as the cohort got older, these mature behaviors got a forceful shove into full-blown recklessness. ""We suspect they may have then engaged in more and more extreme behaviors trying to gain peer approval,"" Allen said. In other words, ""those who got approval for drinking at 13 had to get wasted multiple times and engage in more extreme acts to try, unsuccessfully, to gain approval in later years.""","A constellation of behaviors-minor delinquent activity, precocious romantic involvement, and a focus on physical appearance in friendships -will each be linked to early adolescents' strong desire for status among peers. This constellation will be linked to greater peer popularity in the short term, but this link will fade as adolescence progresses and peers mature. 3.",[1],Medicine,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1093/molbev/msu227,Medicine_easy_119,"They also identified genomic hotspots that seem to play a key role in adaptation and survival, with many having an unknown function.","As we do not observe a dominance of intraspecies clustering in the phylogenetic analysis, these gene families are not evolving in a fashion as would be predicted via concerted evolution.","They found an extensive and robust shuffling of the genomic deck between chlamydia families has played a major role in the evolution of the pathogen, often serving to outwit and exploit its hosts. They also identified genomic hotspots that seem to play a key role in adaptation and survival, with many having an unknown function. Of note, these gene families were most commonly found to have specific protein features gained from their eukaryotic hosts.","S2-S6, Supplementary Material online). As we do not observe a dominance of intraspecies clustering in the phylogenetic analysis, these gene families are not evolving in a fashion as would be predicted via concerted evolution. We provide clear evidence supporting birth-and-death evolution of the PEX and NEX gene families, which is marked by independent gains and losses of members .",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141014085130.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.2337/db13-1600,Medicine_easy_120,"The researchers also confirmed that the spinal cord is the actual physical route by which information from the portal vein travels to the hindbrain, overturning the previous belief that it was transmitted via the vagus nerve.",This would further explain why clamping either portal-mesenteric or brain glycemia during general systemic hypoglycemia is equally effective in blunting the CRR .,"""But neurons in the hindbrain continue to respond to fast onset hypoglycemia even in the absence of peripheral sensors."" The researchers also confirmed that the spinal cord is the actual physical route by which information from the portal vein travels to the hindbrain, overturning the previous belief that it was transmitted via the vagus nerve. ""But it's absolutely essential in slow onset hypoglycemia.""","In this capacity, central glucose sensors might also act primarily to suppress CRRs once euglycemia is reestablished following a hypoglycemic event. This would further explain why clamping either portal-mesenteric or brain glycemia during general systemic hypoglycemia is equally effective in blunting the CRR . What is clear from experiment 3 is that the brain can defend itself against large, rapid declines in blood glucose without portal-mesenteric glucose sensory input.",[1],Medicine,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1210/en.2015-2036,Medicine_easy_121,"Vitamin D and ID1 expression

The researchers found that the 4T1 cell line expresses significantly lower levels of the vitamin D receptor protein.",These results confirmed the in vivo BLI signal data that the VDR KD tumors were substantially larger than control and VDR Rescue tumors.,"Mice fed a diet deficient in vitamin D developed palpable tumors an average of seven days sooner than their peers, and after six weeks of growth those tumors were significantly larger in size than those in animals with adequate vitamin D levels. Vitamin D and ID1 expression

The researchers found that the 4T1 cell line expresses significantly lower levels of the vitamin D receptor protein. When they genetically engineered 168FARN cells to also have lower-than-normal levels of the VDR protein, the cells began to behave much more like the 4T1 cells.","This striking pattern remained consistent until the endpoint of the study when the mice with VDR KD tumors needed to be euthanized for morbidity ( Figure 2B ). These results confirmed the in vivo BLI signal data that the VDR KD tumors were substantially larger than control and VDR Rescue tumors. Remarkably, ex vivo BLI imaging ( Figure 2E ) and direct histology (Supplemental Figure 3) revealed that 60% of the mice with VDR KD tumors had metastatic spread to the liver.",[1],Medicine,train,1.0,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1001/jamainternmed.2016.0157,Medicine_easy_122,"Forty-five (53%) participants reported having hypertension, 41 (91%) of whom reported taking antihypertensive medications.","Results | Of 85 participants, 44 (52%) were women.","Of the remaining 85 participants, 44 (52%) were women, mean age (SD) was 56.6 (16.3) years, body mass index was 27.8 (5.8). Forty-five (53%) participants reported having hypertension, 41 (91%) of whom reported taking antihypertensive medications. The difference between IBP and standard measurements were 12.4 (SD 10.5) mm Hg for systolic BP and 10.1 (SD 8.1) mm Hg for diastolic BP.","Per prespecified dropping rules, data from 16 individuals were discarded because of unavailable cuff sizes (n = 1), standard device errors (n = 2), and excessive variation in sequential standard BP measurements, greater than 12 mm Hg for systolic BP or greater than 8 mm Hg for diastolic BP (n = 1). Results | Of 85 participants, 44 (52%) were women. Their mean (SD) age was 56.6 (16.3) years, and their body mass index, calculated as weight in kilograms divided by height in meters squared, was 27.8 (5.8); 45 (53%) self-reported hypertension, and 91% of these (41) reported taking antihypertensive medications.",[1],Medicine,train,1.0,news,http://www.oncologynurseadvisor.com/instant-blood-pressure-mobile-app-fails-validation-study/article/484459/
10.1001/jamaoncol.2018.3701,Medicine_easy_123,"""The SelectMDx biomarker offers physicians and patients an easily obtained urine-based test, which combines cost effectiveness with clinical utility, improving urologists' ability to diagnose and treat prostate cancer.""","Comparing SEER agespecific rates between the 2007-2011 and 2009-2013 periods, all age groups experienced a decline in incidence of prostate cancer.","""These data further demonstrate the importance of adjunctive biomarkers regarding PSA assessment, especially regarding the decision to either avoid or to proceed to prostate biopsy,"" said principal investigator Neal Shore , M.D., Medical Director at the Carolina Urologic Research Center , Atlantic Urology Clinics in Myrtle Beach, South Carolina. ""The SelectMDx biomarker offers physicians and patients an easily obtained urine-based test, which combines cost effectiveness with clinical utility, improving urologists' ability to diagnose and treat prostate cancer."" SelectMDx was shown to have a significant impact on initial prostate biopsy decision-making.","These men have less than a 10-year life expectancy and are the least likely to benefit from prostate cancer screening; they are more likely to die from a comorbid illness than from prostate cancer. Comparing SEER agespecific rates between the 2007-2011 and 2009-2013 periods, all age groups experienced a decline in incidence of prostate cancer. 29, 30 The age groups with the largest declines were ages 70 to 74 years (a decrease of 112 men per 100 000) and 75 to 79 years (a decrease of 120 men per 100 000).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37616037423&p=1pl&v=1&x=gXp7O7pmGkPY1w04wbVK7A
10.1038/s41467-019-09863-x,Medicine_easy_124,"But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev.","The dynamic model formulation employed here contains the following layers of nonlinearity: nonlinear response of the equilibrium cumulative carbon to GMST changes, represented by the ωφ ω (T)·T term; evolution of the characteristic time lag for cumulative permafrost emissions with the difference between the equilibrium and realised cumulative carbon, represented by p (in the corresponding linear model p = 0 and the lag is simply equal to τ); temperature-dependence in the lag and power parameters, represented by φ τ , φ p ; and, saturation of the cumulative carbon emissions due to the permafrost carbon stock exhaustion, represented by C max .","""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost. But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev. ""The most important thing to remember about our study is the greater the warming, the stronger the feedbacks and the higher the costs to society.""","The pursuit curve model ensures that there is an equilibrium level of cumulative carbon emissions from permafrost for any given level of warming globally (providing p > −1). The dynamic model formulation employed here contains the following layers of nonlinearity: nonlinear response of the equilibrium cumulative carbon to GMST changes, represented by the ωφ ω (T)·T term; evolution of the characteristic time lag for cumulative permafrost emissions with the difference between the equilibrium and realised cumulative carbon, represented by p (in the corresponding linear model p = 0 and the lag is simply equal to τ); temperature-dependence in the lag and power parameters, represented by φ τ , φ p ; and, saturation of the cumulative carbon emissions due to the permafrost carbon stock exhaustion, represented by C max . 7 under the range of scenarios considered.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1001/jamapsychiatry.2018.1941,Medicine_easy_125,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","Many significantly correlated links involved the precuneus, the anterior cingulate cortex, the lateral orbitofrontal cortex, the hippocampus and parahippocampal cortex, and some motor areas ( Figure 2 ; eFigure 2 in the Supplement).","Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","All links that are correlated with the PSQI score are shown in Figure 2 . Many significantly correlated links involved the precuneus, the anterior cingulate cortex, the lateral orbitofrontal cortex, the hippocampus and parahippocampal cortex, and some motor areas ( Figure 2 ; eFigure 2 in the Supplement). The correlation between the sleep quality and the mean strength of these significant functional connectivities is shown in Figure 1A (r = 0.181; P =6.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1111/1365-2656.12871,Medicine_easy_126,"It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked.""","Where, in this instance, we were able to model directly the effect of disease status of individual rabbits on survival, using a larger number of individuals, without assuming discrete periods for RHD epizootics.","Our study shows the first evidence that both viruses work in tandem to control rabbit population numbers. It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked."" ""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus.","This is likely to reflect differences in the two approaches used to analyse the data. Where, in this instance, we were able to model directly the effect of disease status of individual rabbits on survival, using a larger number of individuals, without assuming discrete periods for RHD epizootics. Our finding that RHDV can persist at low levels across the year is independently supported by relatively short-lived immunoglobulin M (IgM), being detected (at titres ≥40) in low numbers of rabbits throughout the year (Supporting Information Figure S10 ).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1073/pnas.1505114112,Medicine_easy_128,"But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life.","Response consistency peaks in childhood (∼8-11 y of age), declining steadily until young adulthood ; we show that this adolescent decline is mitigated by in-school music lessons.","The findings have important implications for teens in low-income neighborhoods, as their language development is often below that of their wealthier counterparts. But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life. Source: Tierney A, Krizman J, Kraus N. Music training alters the course of adolescent auditory development.","The consistency of neural responses to sound tracks with language skills, suggesting that stable perceptual encoding is vital for the acquisition and maintenance of phonological categories . Response consistency peaks in childhood (∼8-11 y of age), declining steadily until young adulthood ; we show that this adolescent decline is mitigated by in-school music lessons. Synaptic density follows a similar developmental trajectory, increasing in early childhood and subsequently declining during adolescence (2-5).",[1],Medicine,train,1.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1002/ejhf.69,Medicine_easy_129,"Heart failure hospitalizations are associated with a poor prognosis irrespective of whether the hospitalization occurred in patients without heart failure or in a patient with previously diagnosed heart failure, or whether the patient has reduced or preserved ejection fraction.","HF with preserved ejection fraction was more common in participants without vascular disease (67.0% vs. 55.0%, P=0.040).","""I say it really does not matter. Heart failure hospitalizations are associated with a poor prognosis irrespective of whether the hospitalization occurred in patients without heart failure or in a patient with previously diagnosed heart failure, or whether the patient has reduced or preserved ejection fraction. The data include new-onset HF in both inpatient and outpatient settings.","There was no significant difference in hospitalizations between those with and without vascular disease (RR 1.04 95%CI: 0.86-1.24 for all-cause, and RR 0.84 95%CI 0.69-1.02 for HF hospitalization). HF with preserved ejection fraction was more common in participants without vascular disease (67.0% vs. 55.0%, P=0.040). Conclusion-A significant proportion of HF in older adults develops without prior vascular disease.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38228224591&p=1pl&v=1&x=VEvBLGqbB4NvvfbrYC9-sA
10.1002/cncr.30428,Medicine_easy_131,"The study showed that median overall survival among patients was 14.5 months, with survival ranging from 0 to 88 months.","Each unit increase in caregiver mastery was associated with a 16.1% decreased hazard of patient death (95% CI, 0.77-0.91, based on 88 cases).","The study showed that median overall survival among patients was 14.5 months, with survival ranging from 0 to 88 months. After controlling for confounding factors, researchers found that caregiver mastery was independently associated with patient survival. Specifically, each unit increase in mastery was associated with a 16.1% reduction in the risk of patient death (95% CI, 0.771-0.913; P <.001).","When known covariates were used in multivariable models (adjusting for the patient's functional status [KPS], postsurgical treatment, type of surgery, and age), only the association between caregiver mastery and patient survival remained statistically significant. Each unit increase in caregiver mastery was associated with a 16.1% decreased hazard of patient death (95% CI, 0.77-0.91, based on 88 cases). Moderate to high versus lower levels of caregiver mastery both appeared to be significantly associated with an extended patient survival time (moderate vs low: hazard ratio, 0.523; 95% CI, 0.30-0.90 [P 5 .020]; and high vs low: hazard ratio, 0.359; 95% CI, 0.20-0.65 [P 5 .001], based on 88 cases).",[1],Medicine,train,1.0,news,http://www.oncologynurseadvisor.com/caregiver-characteristics-and-glioblastoma-multiforme-outcomes/article/569022/
10.1073/pnas.1214971109,Medicine_easy_132,"Applied to gels, this method can predict how the two materials will aggregate to form a new one.","A difference in the local peak between the gels and bigels emerges at ϕ = 0.25, which corresponds to the critical density of the 1CM case .","In the case of the eye, this SNSF Professor highlighted how the mixture of two proteins with very specific characteristics rendered the organ transparent. Applied to gels, this method can predict how the two materials will aggregate to form a new one. The researchers managed to create it so quickly by combining DNA fragments with nanoparticles, a technique in which they are specialized.","In all cases, the structure factor of the gels agrees in a semiquantitative fashion with the structure factor of the bigels. A difference in the local peak between the gels and bigels emerges at ϕ = 0.25, which corresponds to the critical density of the 1CM case . At small interparticle distances (large q), the differences are minimal, whereas at large length scales (small q) the differences are more significant.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2012/11/121105161212.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/gb-2013-14-7-r73,Medicine_easy_133,"""Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,"" said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute.",Our results suggest that gene regulation via vlincRNAs and macroRNAs could be a general theme in human cells.,"Importantly, the group of researchers from U.S., Europe and Russia found that the elimination of these vlincRNAs caused the death of cancer cells. ""Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,"" said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute. ""Future research into the role and function of vlincRNAs holds promise for both highly targeted diagnostic tests and more precise cancer treatments.","These properties make vlincRNA regions similar to macroRNAs which were previously associated only with the regulation of imprinting . Our results suggest that gene regulation via vlincRNAs and macroRNAs could be a general theme in human cells. In this respect, the abundance of these transcripts relative to annotated coding mRNAs is noteworthy.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jama.2009.1943,Medicine_easy_134,"If they were actually correcting chemical imbalances, it would mean that the exact same number of people who are depressed have each kind of chemical imbalance: The proportion of people who have too much serotonin is exactly the same as the fraction who don't have enough norepinephrine.",The present findings indicate that the efficacy of ADM treatment for depression varies considerably as a function of symptom severity.,"In a population of depressed people, they all work equally well. If they were actually correcting chemical imbalances, it would mean that the exact same number of people who are depressed have each kind of chemical imbalance: The proportion of people who have too much serotonin is exactly the same as the fraction who don't have enough norepinephrine. The odds against that are astronomical.","Specific contrasts revealed that the regression coefficient (i.e., the slope representing the relationship between initial severity and change in symptoms) was more positive for each medication class relative to placebo: imipramine, F(1,707)=5.60, p=0.02; and paroxetine, F(1,707)=5.91, p=0.02. The present findings indicate that the efficacy of ADM treatment for depression varies considerably as a function of symptom severity. ""True"" drug effects (an advantage of ADM over placebo) were nonexistent-to-negligible among depressed patients with mild, moderate, and severe baseline symptoms, whereas they were large for patients with very-severe symptoms.",[1],Medicine,train,1.0,news,http://discovermagazine.com/2010/the-brain/09-psychologist-says-antidepressants-are-just-fancy-placebos?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+DiscoverMindBrain+%28Discover+Mind+%26+Brain%29
10.1001/jamaoncol.2018.0798,Medicine_easy_135,"However, patients receiving the therapies are older than those in the clinical trials used to evaluate them, pointing to a disconnect between research and practice that should be addressed, they noted.","36 Although these practices were self-selected, their use of a cloud-based EHR platform allowed for the integration of real-world evidence from a large, geographically diverse cohort of patients with melanoma, NSCLC, or RCC.","The finding suggests that cancer immunotherapies are adopted at a much quicker pace than is typical for newly approved medical treatments, the researchers said. However, patients receiving the therapies are older than those in the clinical trials used to evaluate them, pointing to a disconnect between research and practice that should be addressed, they noted. The researchers found that it took less than four months after approval for the majority of eligible patients to receive treatment with at least one of the drugs.","[25] [26] [27] [28] [29] This issue is particularly relevant to checkpoint inhibitors because of age-related changes in immunity that might alter risks and benefits. 36 Although these practices were self-selected, their use of a cloud-based EHR platform allowed for the integration of real-world evidence from a large, geographically diverse cohort of patients with melanoma, NSCLC, or RCC. Furthermore, these patients were similar in age, sex, and race/ethnicity to the US population of patients with melanoma, NSCLC, and RCC according to estimates of disease prevalence in Surveillance, Epidemiology, and End Results data from 2014.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34024686802&p=1pl&v=1&x=V7M9zzFOhn6CjXB9WZIACw
10.1186/gb-2013-14-7-r73,Medicine_easy_136,"""Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,"" said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute.",Vlinc_185 (C & D) represents an interesting example of a very long antisense transcript.,"Importantly, the group of researchers from U.S., Europe and Russia found that the elimination of these vlincRNAs caused the death of cancer cells. ""Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,"" said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute. ""Future research into the role and function of vlincRNAs holds promise for both highly targeted diagnostic tests and more precise cancer treatments.","Consistent with this, a K562-specific promoter element could be identified at the boundary of vlincRNA_377, upstream of the constitutive promoter controlling the ARL15 expression. Vlinc_185 (C & D) represents an interesting example of a very long antisense transcript. Due to the original constraint of annotating vlincRNAs as intergenic regions, the vlincRNA bounds did not extend over the KCNJ16 gene even though the RNAseq signal clearly extends into that gene (C).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.cmet.2015.02.003,Medicine_easy_137,"After patients were treated with antibiotics, the salt levels in their legs fell, the study reported.",This hypertonic microenvironment was accompanied by a significant reduction of L. major burden at the end of the experiment (2 nd time point; Figure 4B ).,"""(I)nfected legs showed massive salt accumulation, while the uninfected legs were totally normal,"" Titze said. After patients were treated with antibiotics, the salt levels in their legs fell, the study reported. [STORY: Challenging convention: Visual cortex not solely responsible for processing images]

Despite the positive results, researchers warned that a high-salt diet should not be seen as a healthy regular routine.","Improved healing was paralleled by increased (Na + + K + )/H 2 O ratio in HSD mice ( Figure 4B ). This hypertonic microenvironment was accompanied by a significant reduction of L. major burden at the end of the experiment (2 nd time point; Figure 4B ). We found a tendency toward increased IFN-g production in HSD mice, suggesting that Leishmania-specific T cell responses may be involved in improved host defense with HSD ( Figure 4B ).",[1],Medicine,train,1.0,news,http://www.redorbit.com/news/health/1113346345/salty-skin-may-ward-off-infection-030415/
10.1136/bmjsem-2017-000261,Medicine_easy_138,"It might have done so by triggering an anticipatory feeling of stress, brought on by the memory of games past.",This finding is further supported by Kivlighan et al 19 who identified that the anticipatory cortisol response in a created rowing competition was significantly lower in more experienced athletes compared with novices.,"While we donat know exactly how the alerts matched up with the spikes in heart rate, itas fair to assume that the stress of the game generally stimulated the sympathetic nervous systems of the fans. It might have done so by triggering an anticipatory feeling of stress, brought on by the memory of games past. This is not, after all, the first time people have reported that watching the English national team play was enough to precipitate a full-fledged biological stress response.","that the emotional response (eg, cognitive anxiety) before sport competition was significantly lower in more experienced athletes compared with less experience players. This finding is further supported by Kivlighan et al 19 who identified that the anticipatory cortisol response in a created rowing competition was significantly lower in more experienced athletes compared with novices. The results of our analysis on the level of competition might be influenced by the level of experience of the athletes within the studies.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34474732617&p=1pl&v=1&x=pcdQFFmMveKF7UrJyJtzvg
10.1001/jamaneurol.2017.4618,Medicine_easy_139,"In addition, the positive and negative predictive values were 73.1 percent and 91.2 percent, respectively.","The sensitivity and positive predictive value of ABLDs to assess the probability of DNS was approximately 75%, and the specificity and negative predictive value were approximately 90%.","The sensitivity and specificity of acute brain lesions to assess the probability of delayed neurological sequelae were 75.2 percent and 90.2 percent, respectively. In addition, the positive and negative predictive values were 73.1 percent and 91.2 percent, respectively. The researchers concluded that the presence of acute brain lesions was significantly associated with the development of delayed neurological sequelae.","14,17 Importantly, we showed that the presence of ABLDs during the acute phase of CO poisoning was significantly associated with a 14-fold higher risk of developing DNS in the future compared with those who did not have ABLDs. The sensitivity and positive predictive value of ABLDs to assess the probability of DNS was approximately 75%, and the specificity and negative predictive value were approximately 90%. Therefore, we concluded that DWI is a useful modality for detecting ABLs and assessing the probability of DNS in patients with CO poisoning.",[1],Medicine,train,1.0,news,http://www.diagnosticimaging.com/article/imaging-may-identify-potential-delayed-neurological-sequelae-after-carbon-monoxide-poisoning
10.1073/pnas.1408439111,Medicine_easy_140,"However, anonymous phone data can be examined regularly to map daily, weekly or monthly changes across an entire country, at less cost and with greater flexibility.","rate (i.e., the percentage of active MP subscriptions within the population) reached 96% in 2014 .","Their findings show maps made using mobile records are detailed, reliable and flexible enough to help inform infrastructure and emergency planners; particularly in low income countries, where recent population density information is often scarce. However, anonymous phone data can be examined regularly to map daily, weekly or monthly changes across an entire country, at less cost and with greater flexibility. When this information is repeated multiple times, over millions of users, we can extract a detailed picture of population density and how it changes over time in a given area.""","The work highlights how facilitating access to anonymized mobile phone data might enable fast and cheap production of population maps in emergency and data-scarce situations. rate (i.e., the percentage of active MP subscriptions within the population) reached 96% in 2014 . Each MP communication can be located by identifying the geographic coordinates of its transmitting tower and the associated cell.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082456.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1210/jc.2013-2350,Medicine_easy_141,"Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants.","When estrogenic activity prevails, there is an increase in HDL-cholesterol and a decrease in LDL-cholesterol levels, whereas the opposite occurs when androgenic activity is higher .","Women who had PCOS also had a higher rate of endometrial cancer, or cancer of the lining of the uterus. Women diagnosed with PCOS were hospitalized more often for mental health disorders such as depression, stress and anxiety than other study participants. A PCOS diagnosis also was associated with a higher risk of late onset diabetes, high blood pressure, heart disease, asthma and musculoskeletal disorders.","As with glucose metabolism, the effect of HCs on lipid balance appears to be related to the formulation used. When estrogenic activity prevails, there is an increase in HDL-cholesterol and a decrease in LDL-cholesterol levels, whereas the opposite occurs when androgenic activity is higher . However, lipids seem to be less sensitive to the residual androgenic properties of the progestins 213, 216 -218) .",[1],Medicine,train,1.0,news,http://www.healthcanal.com/female-reproductive/59582-women-diagnosed-with-pcos-twice-as-likely-to-be-hospitalized.html
10.1377/hlthaff.2012.1030,Medicine_easy_142,"However, she says, the new bundled payment models are different because insurers are adding quality measures that increase accountability to the bundle, as well as additional services such as labor and delivery.","Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals.","And they are more expensive than a vaginal delivery. However, she says, the new bundled payment models are different because insurers are adding quality measures that increase accountability to the bundle, as well as additional services such as labor and delivery. Expanding the rarely used model to include maternity care could represent a major shift in health care finance.","Even for women with lower-risk pregnancies, in which more limited variation might be expected, cesarean rates varied fifteenfold, from 2.4 percent to 36.5 percent. Thus, vast differences in practice patterns are likely to be driving the costly overuse of cesarean delivery in many US hospitals. Because Medicaid pays for nearly half of US births, government efforts to decrease variation are warranted.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=40237818568&p=1pl&v=1&x=UbIfZ6fwxC-SSLoUKpAuow
10.1126/science.1222939,Medicine_easy_143,"The deal sheds light on Allergan's renewed strategic focus on new neuroscience drugs, Nicholson said.",These findings are consistent with cell culture studies demonstrating that glutamate receptor stimulation of synaptogenesis requires the release of BDNF to stimulate TrkB-mTOR signaling and synaptic protein synthesis (50) .,"If successful in clinical trials, the pill could also be used ""more widely"" than Rapastinel, Nicholson said. The deal sheds light on Allergan's renewed strategic focus on new neuroscience drugs, Nicholson said. Nicholson also believes that the interest he's seeing in ketamine-inspired drugs could be the breakthrough needed to stir-up renewed interest among drugmakers in the neuroscience field, which declined somewhat after several promising Alzheimer's drug candidates failed to turn into treatments.","In addition, the synaptogenic actions of ketamine are blocked in mice with a knock-in of the BDNF Met allele that impairs BDNF mRNA transport to dendrites, as well as in conditional BDNF mutant mice (32, 49) . These findings are consistent with cell culture studies demonstrating that glutamate receptor stimulation of synaptogenesis requires the release of BDNF to stimulate TrkB-mTOR signaling and synaptic protein synthesis (50) . Activity-dependent release of BDNF could also explain why ketamine is more rapid and efficacious than conventional antidepressants, which increase the expression but not the release of BDNF.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34189390342&p=1pl&v=1&x=etXjO4wOmixSyFpWlcC00g
10.1016/j.cub.2013.09.038,Medicine_easy_144,"Pond scum's algae make good lab models for analyzing this because they reproduce quickly, and they have cellular structure and cilia that closely parallel ours.","The abnormal flagellar lengths of cnk2-1, lf4-7, and lf4-7 cnk2-1 can be explained by perturbations in the rates of flagellar assembly or disassembly.","When growing and shrinking happen simultaneously cilia length remains constant. Pond scum's algae make good lab models for analyzing this because they reproduce quickly, and they have cellular structure and cilia that closely parallel ours. ""We were able to deduce how the mutations affected the cilia's assembly and disassembly by measuring how much and how quickly green fluorescence appeared at the tip of the untagged cilia,"" explains Quarmby.","Furthermore, we observed that lf4-7 cnk2-1 double-mutant flagella were resistant to the effects of IBMX and NaPPi on flagellar resorption, whereas lf4-7 single mutants resorbed faster than wild-type in response to either chemical ( Figures 3F and 3G) . The abnormal flagellar lengths of cnk2-1, lf4-7, and lf4-7 cnk2-1 can be explained by perturbations in the rates of flagellar assembly or disassembly. In cnk2-1 mutants, flagella that grow too long are unable to activate disassembly but compensate by decreasing the assembly rate.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131031124920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1377/hlthaff.2012.1030,Medicine_easy_145,"Dr. Stan Davis, an obstetrician and consultant to the Minnesota Hospital Association, said he, too, was alarmed by the findings.",25 A targeted approach to achieving such reductions might focus on hospitals with exceptionally high cesarean rates.,"""It should be concerning to all women to see this kind of variability,"" she said. Dr. Stan Davis, an obstetrician and consultant to the Minnesota Hospital Association, said he, too, was alarmed by the findings. ""What it tells me is that people really aren't following evidence-based guidelines for when they should be doing Caesareans,"" he said.","20 Adverse outcomes and complications have substantial cost implications for delivery systems and health insurers, both public and private. 25 A targeted approach to achieving such reductions might focus on hospitals with exceptionally high cesarean rates. 26 Understanding the extent of variation and its causes may provide opportunities for identifying policy options to improve care.",[1],Medicine,train,1.0,news,http://www.startribune.com/lifestyle/health/195072291.html
10.1038/s41590-018-0068-4,Medicine_easy_146,These new findings will enable researchers to use targeted vaccine adjuvants to activate follicular helper cells and thus antibody responses.,"Conversely, supplementing supernatants of unstimulated (control) APCs with recombinant IL-12 restored T FH cell differentiation (Fig.",TLR8 induced signals call into action a specialized type of immune cell known as follicular helper cells. These new findings will enable researchers to use targeted vaccine adjuvants to activate follicular helper cells and thus antibody responses. The researchers found that live bacteria elicited slightly altered immune responses within the innate immune system.,"Neutralization of IL-6 or IL-27 had no significant effect, whereas blockade of TNF partially inhibited T FH cell differentiation, relative to such differentiation after the addition of isotype-matched control antibodies (Fig. Conversely, supplementing supernatants of unstimulated (control) APCs with recombinant IL-12 restored T FH cell differentiation (Fig. Supplementation with recombinant TNF alone did not promote T FH cell differentiation (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33723683656&p=1pl&v=1&x=R9OQAdHcxos4adubuX4cGg
10.1016/j.jcmg.2015.08.018,Medicine_easy_147,"Dr Vanessa Ferreira, Deputy Clinical Director of the OCMR, said: 'The potential of this research is huge - not only for heart scans.","At rest, the remote myocardial T1 (955 AE 17 ms) was comparable to normal controls at 1.","Dr Liu added: 'Further studies will concentrate on how we can use T1 mapping not only to improve our research but eventually develop this into a tested, clinically proven technique for use with patients worldwide.' Dr Vanessa Ferreira, Deputy Clinical Director of the OCMR, said: 'The potential of this research is huge - not only for heart scans. Each type of tissue across the body has a range of normal T1 values, so any values outside that range may signify disease.","10 patients showed evidence of previous myocardial infarction on LGE remote from the ischemic territories ( Table 2) . At rest, the remote myocardial T1 (955 AE 17 ms) was comparable to normal controls at 1. There was no significant stress dT1 reactivity in ischemic (0.2 AE 0.8%) or infarcted (0.2 AE 1.5%) myocardium compared to controls at 1.5-T (all p < 0.001).",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/yOFStVEGom0/
10.1073/pnas.1318978111,Medicine_easy_148,Hammes says the study calls for further clinical trials to determine whether androgens can have a positive effect on fertility when given at the right doses.,Androgen Treatment Enhances Follicular Sensitivity Toward FSH Actions.,"""If these data are confirmed in clinical trials, we could propose that raising low levels of androgens in a woman with diminished ovarian reserve might increase her ability to produce more and better eggs for fertilization."" Hammes says the study calls for further clinical trials to determine whether androgens can have a positive effect on fertility when given at the right doses. And, by better understanding the biological pathways that are important for follicle development, scientists may be able to target these pathways with drugs or other interventions to improve IVF success rates.","Accordingly, inhibition of the nongenomic AR-induced signaling by using flutamide, the MEK inhibitor U0126, or siRNA-mediated paxillin knockdown abrogates DHT-induced FSHR expression, whereas reexpression of paxillin in paxillin-knockdown GCs partially rescues DHT-induced FSHR expression ( Fig. Androgen Treatment Enhances Follicular Sensitivity Toward FSH Actions. Although FSH alone promotes follicular growth, addition of DHT in a dose-dependent manner significantly increases follicular growth (Fig.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2018.04.034,Medicine_easy_149,More study is needed to understand this.,"Interestingly, certain direct pro-tumor chemokines, including CCL18 and CXCL8 (Nagarsheth et al., 2017), were enriched in patients with CDK12 mutations.","It could also explain why some prostate cancer patients have had exceptional responses to immunotherapy while the treatment has had lackluster results overall in prostate cancer. More study is needed to understand this. ""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation.","Overall, we observed reduced or low expression of chemokines that can recruit regulatory T cells (CCL17, CCL20, CCL22) (Curiel et al., 2004; and an increase in chemokines that support dendritic cell migration into the tumor microenvironment (CCL21, CCL25). Interestingly, certain direct pro-tumor chemokines, including CCL18 and CXCL8 (Nagarsheth et al., 2017), were enriched in patients with CDK12 mutations. Strikingly, only MMRD and CDK12 mutant tumors showed robust activation of chemokine signaling/inflammatory response and high immune infiltration as estimated by the cohort MImmScore (Figures 6B and S7B) .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1098/rsbl.2014.0993,Medicine_easy_150,"If changing weather patterns begin to clog the normally clear summer sky with layers of clouds, Rydin says, that turn of events ""would probably be disastrous for E.","In the sympatric but wind-pollinated Ephedra distachya, pollination is not correlated to the full moon but occurs at approximately the same dates every year.","The researchers are also curious--and concerned--about another observation. With its dependence on getting nocturnal lighting just right, Rydin and Bolinder wonder if E. foeminiea might be suffering ill effects due to light pollution. If changing weather patterns begin to clog the normally clear summer sky with layers of clouds, Rydin says, that turn of events ""would probably be disastrous for E.","Further, the spectacular reflection of the full-moonlight in the pollination drops is the only apparent means of nocturnal attraction of insects in these plants. In the sympatric but wind-pollinated Ephedra distachya, pollination is not correlated to the full moon but occurs at approximately the same dates every year. The lunar correlation has probably been lost in most species of Ephedra subsequent an evolutionary shift to wind pollination in the clade.",[1],Medicine,train,1.0,news,http://www.smithsonianmag.com/science-nature/wereplant-releases-its-pollen-by-light-full-moon-180954827/
10.1038/nature24621,Medicine_easy_152,"Overall, the microbiomes of a host, such as a human or animal, were quite distinct from free-living microbiomes, such as those found in water and soil.",Figure 4 | Specificity of sequences and higher taxonomic groups for environment.,"The diversity of environments sampled by the Earth Microbiome Project helps demonstrate just how much local environment shapes the microbiome. Overall, the microbiomes of a host, such as a human or animal, were quite distinct from free-living microbiomes, such as those found in water and soil. ""These global ecological patterns offer just a glimpse of what is possible with coordinated and cumulative sampling,"" Jansson says.","Given current global sequencing efforts, the use of coordinated protocols and submission to this and other public databases should allow rapid accumulation of new data, providing an ever more diverse reference catalogue of microbes and microbiomes on Earth. Figure 4 | Specificity of sequences and higher taxonomic groups for environment. Each bar depicts the distribution of environments for a taxon (not relative abundance of taxa): bars composed mostly of one colour (environment) are specific for that environment, as seen with tag sequences; bars composed of many colours are more cosmopolitan, as seen with genera.",[1],Medicine,train,1.0,news,http://www.futurity.org/earth-microbiome-project-1595972/
10.1098/rspb.2013.3172,Medicine_easy_153,Predictive modelling can help public health officials plan for responses to vaccine programs.,"Future research should refine the inclusion of social norms in such models and explore how social norms interact with interventions, namely public health messaging strategies.","""Our research suggests that health officials needs to have a really good understanding of the social context to better understand vaccine scares and why people refuse vaccines. Predictive modelling can help public health officials plan for responses to vaccine programs. The models that Professor Bauch and his colleagues use can determine what may happen in a population where a vaccine scare has taken hold.","Incorporating social norms into behaviour-incidence models enables them to capture a wider range of vaccinating behaviour, including patterns of high, stable vaccine coverage observed in many populations under a non-mandatory policy. However, from a public health perspective, social norms can act to either decrease or increase vaccine coverage, depending on the baseline perception of vaccine risk. Future research should refine the inclusion of social norms in such models and explore how social norms interact with interventions, namely public health messaging strategies.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140214111211.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/eurheartj/ehq155,Medicine_easy_154,"Even though the genetic component can control for confounding factors like smoking and poor diet, it can't control for lifestyle factors that are a direct consequence of being shorter.",Height cut-offs were available for 21 articles.,"The study comes with some limits, the authors concede. Even though the genetic component can control for confounding factors like smoking and poor diet, it can't control for lifestyle factors that are a direct consequence of being shorter. It may be the case, for instance, that genetically determined shortness, for whatever reasons, influences people to take up behaviors that increase their heart disease risk.","When men and women were considered independently on average, short men were below 165.4 cm and short women below 153.0 cm, tall men over 177.5 cm and tall women over 166.4 cm. Height cut-offs were available for 21 articles. Only one article failed to report height cut-offs and was not taken into the calculations.",[1],Medicine,train,1.0,news,http://www.medicaldaily.com/heart-disease-more-common-shorter-people-due-partly-cholesterol-and-fat-levels-328630
10.1016/j.ebiom.2014.09.001,Medicine_easy_155,They researchers have now reached the point that they can avoid taking painful blood marrow samples and complete the entire process in the matter of a week.,S3A -C. Cells positive for the leukocyte common antigen CD45 were found mainly in the adventitia and not the lumen of the veins (Fig.,"In the third case the child is under medical surveillance and the outcome is more uncertain. They researchers have now reached the point that they can avoid taking painful blood marrow samples and complete the entire process in the matter of a week. ""We believe that this technological progress can lead to dissemination of the method for the benefit of additional groups of patients, such as those with varicose veins or myocardial infarction, who need new blood vessels,"" Professor Holgersson says.","Negative controls are shown in Supplement Fig. S3A -C. Cells positive for the leukocyte common antigen CD45 were found mainly in the adventitia and not the lumen of the veins (Fig. 3C ), indicating that these cells mainly differentiated to smooth muscle cells as evidenced by positive staining for alpha smooth muscle cell actin.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141024101256.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04355-w,Medicine_easy_156,"Also, when looking at tumor samples from patients, they found that tumors with high amounts of the fibrin cross-linking was associated with an increased risk of the tumor spreading.",These results strongly suggest that the therapeutic effects arose from blocking IM recruitment into the TME.,"They also demonstrated that the presence of a clot made it easier for cancer cells to move and migrate. Also, when looking at tumor samples from patients, they found that tumors with high amounts of the fibrin cross-linking was associated with an increased risk of the tumor spreading. The researchers were able to reduce metastases by using a compound that blocks CCR2, a receptor on the surface of the inflammatory monocytes.","Additionally, we found no significant effects on recruitment of gamma-delta T-cells ( Supplementary Fig. These results strongly suggest that the therapeutic effects arose from blocking IM recruitment into the TME. Additionally, CCR2 blockade with PF-04136309 significantly inhibited metastasis development when treatment was initiated on the day of cancer cell injection (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34143256224&p=1pl&v=1&x=_B116Taw-aRVfBzYTF8X0Q
10.1101/gad.263707.115,Medicine_easy_158,"They showed that when fewer chemical groups of a certain type attach to yeast histones, the abnormal transcription greatly increases in old cells.","S4 ), extends life span, suggesting that trimethylated H3K36 specifically may regulate longevity.","This number - a mean of 25 divisions -- is under tight control and can be either reduced or increased by altering histone modifications, as the researchers found. They showed that when fewer chemical groups of a certain type attach to yeast histones, the abnormal transcription greatly increases in old cells. In contrast, the team found that in yeast strains with a certain enzyme deletion, this abnormal transcription is reduced and lifespan is extended by about 30 percent.","Rph1 removes methyl groups from dimethylated and trimethylated H3K36, whereas Jhd1 does so from dimethyl and monomethyl states. S4 ), extends life span, suggesting that trimethylated H3K36 specifically may regulate longevity. Supporting the high-throughput histone mutant screen data, all of the H3K36 substitution mutants showed significantly shorter life spans (Fig.",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/cell-aging-slowed-by-putting-brakes-on-noisy-transcription
10.1007/s13524-014-0324-7,Medicine_easy_159,But it probably does affect earning potential.,There are several reasons to expect that occupational segregation would be nonrandom with respect to mobility.,"Men are much more likely to choose jobs that are concentrated in certain geographical areas, while women choose jobs that are needed everywhere. But it probably does affect earning potential. This table shows which professions are most geographically concentrated, and which are the most dispersed.","As such, occupational segregation is a potential source of omitted variable bias. There are several reasons to expect that occupational segregation would be nonrandom with respect to mobility. First, if men and women expect families to prioritize husbands' careers in relocation decisions, this may in turn compel women to sort into flexible occupations, thereby reproducing occupational segregation.",[1],Medicine,train,1.0,news,http://www.businessinsider.com/why-women-choose-more-flexible-careers-2014-11
10.1126/science.1252496,Medicine_easy_161,"Analysis revealed that it had caught about a million particles, and since then astronomers have been working through the data to understand what story these particles tell us about our solar system, its origin and the universe beyond.",The remaining 25 so-called midnight tracks have trajectories that are consistent with an origin either in the interstellar dust stream or as ejecta from impacts on the lid of the sample return capsule (20) .,"Analysis revealed that it had caught about a million particles, and since then astronomers have been working through the data to understand what story these particles tell us about our solar system, its origin and the universe beyond. The list of particles has now been finally whittled down to seven particles that scientists are sure originated outside the solar system. ""We think that we have just taken the first baby step in understanding the complexity and diversity of interstellar dust,"" he said.","Forty-six of the tracks are consistent in their trajectories with an origin as secondary ejecta from impacts on the aft solar panels, and this origin was confirmed for four tracks (12) (13) (14) (15) by the presence of cerium, a cosmically rare element present in the glass covering the spacecraft solar panels. The remaining 25 so-called midnight tracks have trajectories that are consistent with an origin either in the interstellar dust stream or as ejecta from impacts on the lid of the sample return capsule (20) . The ambiguity in origin of these 25 tracks is due to the articulation of the collector on its arm during the exposure (27) .",[1],Medicine,train,1.0,news,http://www.theepochtimes.com/n3/883210-spacecraft-captured-dust-from-beyond-our-solar-system/
10.1038/ncomms4632,Medicine_easy_162,"But first they plan to test their nanomotors near a live cell, which will allow Fan to measure how they deliver molecules in a controlled fashion.",These two effects can be known from the slopes of o-V 2 plots in Fig.,"The researchers address two major issues for nanomotors so far: assembly and controls. The researchers found that they could position the nanomotors in a pattern and move them in a synchronized fashion, which makes them more powerful and gives them more flexibility. But first they plan to test their nanomotors near a live cell, which will allow Fan to measure how they deliver molecules in a controlled fashion.","This induced torque has two roles on the rotation of nanomotors, both of which are proportional to E 2 and thus V 2 : first, it directly hinders the rotation of nanorotors; second, it results in an additional frictional torque between the rotor and bearing because of the electrostatic attraction, besides that arisen from the magnetic attraction. These two effects can be known from the slopes of o-V 2 plots in Fig. 3a , where the rotation slopes of a nanowire motor (blue, black and magenta) are consistently lower than that of the same nanowires when freely rotating (orange).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1811993115,Medicine_easy_163,"The findings could drive the development of new, more effective antibiotics.","The weak-coupling region of the spectra reveals at least one more 1 H coupling from the aromatic side chain; however, we could not confidently determine its hyperfine constant, owing to interference from weakly coupled, nonexchangeable 1 H atoms of the protein matrix.","This process may allow infectious bacteria to replicate even when the host's immune system sequesters iron and manganese ions in an attempt to slow pathogen replication. The findings could drive the development of new, more effective antibiotics. If you have a way to make DNA that doesn't rely as much on a metal cofactor, that's a novel tactic for evading the immune response,"" he says.","4 B  and C) . The weak-coupling region of the spectra reveals at least one more 1 H coupling from the aromatic side chain; however, we could not confidently determine its hyperfine constant, owing to interference from weakly coupled, nonexchangeable 1 H atoms of the protein matrix. A pair of ENDOR signals identified in all studied samples was unaffected by the isotopolog of Tyr or solvent and accounted for in simulations (see below) by a dipolar coupling of approximately 1.0-1.5 MHz.",[1],Medicine,train,1.0,news,https://www.futurity.org/enzymes-bacteria-immune-systems-1898942/
10.1002/emmm.201302567,Medicine_easy_164,"Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views).",These findings suggested the importance of liver pathogenesis in SMA.,"Using TSUNAMI, Dr. Krainer's team induced various pathologies characteristic of Type IV (adult) SMA. Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views). (click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults.","However, the H&E-stained heart sections did not show cellular abnormalities. These findings suggested the importance of liver pathogenesis in SMA. Consistent with this notion, IP injection of 200 mg/kg/day ASO-20-37 markedly inhibited SMN2 splicing in the liver and decreased lifespan (Figs 2C and 3E) .",[1],Medicine,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1098/rsos.171474,Medicine_easy_165,"""In one voice, our nation must condemn racism, bigotry and white supremacy.","Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function.","""Words do matter"": Trump acknowledged ""white supremacy,"" but ignored his own rhetoric

In his remarks at the White House, Trump denounced racism, calling out an anti-Hispanic screed apparently written by the suspect in the El Paso, Texas, shooting. ""In one voice, our nation must condemn racism, bigotry and white supremacy. These sinister ideologies must be defeated.","The discussion presents an interpretation of this pattern of effects in terms of both the ongoing scientific and policy debates around violent video games, and emerging standards for robust evidence-based policy concerning young people's technology use. Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function. There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39881272230&p=1pl&v=1&x=agjUuQHKttCmyqc0lNUvPA
10.1093/schbul/sbv109,Medicine_easy_166,"Media queries and interview requests should be directed to:

Department of Psychosis Studies, Institute of Psychiatry, Psychology Neuroscience, KingaEUR(tm)s College London, London SE5 8AF, UK; tel: +44 (0)20 7848 0289, e-mail: a.mechelli@kcl.ac.uk","The details of the image acquisition sequence varied between scanners, as reported in supplementary table S1.","Their work provides additional evidence that this region may provide valuable information that could be used to inform diagnostic evaluations in not only schizophrenia but other Axis I disorders such as bipolar disorder, depression, addiction, obsessive-compulsive disorder and anxiety regardless of ethnicity. ###

The paper aEURoeA Neuroanatomical Signature for Schizophrenia Across Different Ethnic GroupsaEUR can be accessed here: http://schizophreniabulletin.oxfordjournals.org/content/early/2015/08/10/schbul.sbv109.full?sid=a9367e61-bbdf-4a49-9772-cd42ee6cb619

Note to Reporters:

Any mention or reporting of data from this article should be attributed to: Schizophrenia Bulletin, published by Oxford University Press, seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. Media queries and interview requests should be directed to:

Department of Psychosis Studies, Institute of Psychiatry, Psychology Neuroscience, KingaEUR(tm)s College London, London SE5 8AF, UK; tel: +44 (0)20 7848 0289, e-mail: a.mechelli@kcl.ac.uk","All patients in the Chinese sample were medication naïve at the time of scanning; in contrast, patients in the White Caucasian, African-Caribbean and Japanese samples were taking first-or second-generation antipsychotic medication, or a combination of the two (see table 1 for chlorpromazineequivalent dose). The details of the image acquisition sequence varied between scanners, as reported in supplementary table S1. With respect to sociodemographic parameters, within each group patients and controls were individually matched for ethnicity, gender and age (±1 year); hence these variables did not differ between patients and controls in any of the 4 groups (P > .05).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/researchers-find-neuroanatomical-signature-for-schizophrenia/
10.1038/s41598-017-03627-7,Medicine_easy_167,"I want it in the same way that I want to be a person who likes watching sports, or finds George Clooney attractive, because both seem to be experiences that have brought a lot of joy to a lot of people.",(Fig.,"But arriving here made me oddly sad, the kind of sadness that comes with realizing that something you like about yourself isn't really true. I want it in the same way that I want to be a person who likes watching sports, or finds George Clooney attractive, because both seem to be experiences that have brought a lot of joy to a lot of people. And it's lonely being on the outside, especially when the experience in question is such a quietly lovely one.","The CLO analysis indicated that touch and pain moderated the partners' velocity effect both in men and in women (F (4,55000) = 14.44, p < 0.0001, ΔBIC = −47.8, ΔR 2 = 0.18), indicating that the partner's velocity effect differed across experimental conditions. (Fig. This pattern of effects describes a consistent pattern of inhalation among women while men shift from inhalation to exhalation.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1111/gcb.13876,Medicine_easy_168,"For example, we need to end policies that perversely encourage the use of forest land and products under a false banner of renewable energy.",They are not meant to represent future projections of land management.,"Of course, there remains much work yet to come. For example, we need to end policies that perversely encourage the use of forest land and products under a false banner of renewable energy. While it is true that trees burned to generate electricity may eventually grow back and recapture the carbon emitted, we need to keep carbon out of the atmosphere now, not in 50 years.","These simulations set bounds on the biophysical potential for negative emissions. They are not meant to represent future projections of land management. Gross emissions did not fall to zero in 2016 when land use stopped but did decline exponentially, as expected from rates of decay, and were about 0.1 PgC/year by 2100.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34958843662&p=1pl&v=1&x=ADGn1_xewWPJ_1OZt5xdOA
10.3402/ejpt.v5.22250,Medicine_easy_170,"If a therapist makes you uncomfortable or raises red flags for you, you don't have to see them.","However, a sample size of 11 does limit the number of inferential statistical tests that can meaningfully be performed.","Also, you can always decide they aren't a good match for you. If a therapist makes you uncomfortable or raises red flags for you, you don't have to see them. People seem to forget this sometimes.a

Despite the profound challenges that both trauma and DID have given Joubert, she also says that her systemas adaptation to trauma has been nothing short of lifesaving.","However, interpretations such as these will have to wait for more data and replication before being supported. However, a sample size of 11 does limit the number of inferential statistical tests that can meaningfully be performed. The small number of participants meant that observed power was very low in many of the analyses.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1038/s41467-018-07557-4,Medicine_easy_172,"""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality.""",Our results demonstrate that ca.,"""These observations have led me to believe that the global warming is not a 'fake' but the reality,"" Romanovsky said. ""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The Paper May Be Misleading

Even though the researchers of this study insist that global warming threat is real, Christopher Burn, a professor of geography and environmental studies at Carleton University, Canada, explains that the paper does not reveal anything that they don't already know.","Our study reveals the magnitude of the threat to engineering structures from climate change at the pan-Arctic scale, and shows where detailed infrastructure risk assessment should be conducted in the near future. Our results demonstrate that ca. The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37967333906&p=1pl&v=1&x=ltio0H7-Rr6r3LuvSX7DEA
10.1038/s41467-018-05229-x,Medicine_easy_174,"""If the electric field inside the crystal is strong enough, the electronic states can be localized to a few atoms.","5 ), a slight resonant background is indeed building up gradually, but it is of negative sign in ΔT/T.","""In perfect insulators and semiconductors, electronic states expand throughout the entire crystal. ""If the electric field inside the crystal is strong enough, the electronic states can be localized to a few atoms. The short-lived Wannier-Stark localization correlates with drastic changes to the electronic structure of the crystal and results, for example, in extremely high optical nonlinearity.","Instead, a gradual buildup of a positive background would indicate a significant influence of bleaching due to real carriers induced by the high bias. 5 ), a slight resonant background is indeed building up gradually, but it is of negative sign in ΔT/T. We attribute this signature to the transient broadening of the E 1 and E 1 + Δ 1 gaps around 3 eV (see Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1098/rsos.171474,Medicine_easy_176,"""We must stop the glorification of violence in our society,"" he said.",A total of 48.8% of female participants and 68.0% of males played at least one violent game in the past month.,"""The idea of these video games, they dehumanize individuals to have a game out of shooting individuals and others,"" McCarthy said. ""We must stop the glorification of violence in our society,"" he said. ""This includes the gruesome and grisly video games that are now commonplace.""","Most games could be easily categorized by the coder, and this approach contrasts with research practices that either: (i) assign participants to play 'off the shelf' games that broadly represent the categories of violent and non-violent play, leaving open the possibility of other game characteristics such as difficulty having a confounding role or (ii) depend on the accuracy of participants providing subjective ratings of the violence present in their own gaming [ . A total of 48.8% of female participants and 68.0% of males played at least one violent game in the past month. To examine this issue, we tested relations with gender, and observed higher levels of overall gaming, t 764 ¼ 3.71, p , 0.001, violent gaming, t 764 ¼ 4.09, p , 0.001 and aggressive behaviour, t 999 ¼ 2.98, p , 0.001, in adolescent boys as compared to adolescent girls.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882021759&p=1pl&v=1&x=WDSVA9_GGY2tcF2kX9kO8w
10.1073/pnas.98.2.676,Medicine_easy_178,"Nixon notices a correlation: In the past decade, productivity growth has slowed while global shipments of smartphones have risen.",Note the large variation in blood flow and oxygen consumption across regions of the brain.,"This is not an idle thought, but a serious question recently posed by the Bank of England. Nixon notices a correlation: In the past decade, productivity growth has slowed while global shipments of smartphones have risen. Therefore, Nixon doesn't try to offer a definitive answer to the question but rather a way to think about it.",These decreases appear to be largely task independent. Note the large variation in blood flow and oxygen consumption across regions of the brain. These vary most widely between gray and white matter.,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=32673885352&p=1pl&v=1&x=z9sHRU5NAQouqrkI5zIhAw
10.1073/pnas.1505114112,Medicine_easy_179,These findings suggest that musical training could keep that window open longer.,"Perhaps rapid automatized naming, which is dissociable from phonological awareness and makes an independent contribution to reading skill , relies on precise perception of auditory timing to a lesser extent than does phonological awareness.","At the end of 3 years, those students who had played instruments were better at detecting speech sounds, like syllables and words that rhyme, than their JROTC peers, the team reports online today in the Proceedings of the National Academy of Sciences. These findings suggest that musical training could keep that window open longer. But the benefits of music aren't just for musicians; taking up piano could be the difference between an A and a B in Spanish class.","On the other hand, we found no gains in rapid naming or phonological memory, despite the fact that both reading and verbal memory have been associated with music training in other studies, suggesting either that the training studied here was not optimally designed to enhance these skills or that enhancing these skills requires a greater amount of training or training begun earlier in life. Perhaps rapid automatized naming, which is dissociable from phonological awareness and makes an independent contribution to reading skill , relies on precise perception of auditory timing to a lesser extent than does phonological awareness. An unavoidable limitation of this study was that, due to working with in-school programs, we were not able to randomly assign participants to one or the other training group.",[1],Medicine,train,1.0,news,http://news.sciencemag.org/brain-behavior/2015/07/benefits-band-class
10.1038/s41598-018-30980-y,Medicine_easy_180,"""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.",Greater nap slow wave activity was associated with greater memory decay during the nap.,"As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.3945/jn.110.130609,Medicine_easy_182,The position change recommended through the study is for the baby to be held at the level of the mother's placenta before the umbilical cord is clamped.,All of the indicators available at the present time are affected by factors other than ID that may remain undetected in random samples ( Table 1) .,"It demonstrates that newborns who are held immediately after birth, for as little as two minutes before clamping the umbilical cord, have increased blood flow from the mother's placenta to the baby. The position change recommended through the study is for the baby to be held at the level of the mother's placenta before the umbilical cord is clamped. While this position is uncomfortable and awkward for the person holding the newborn, the research says it can make a significant difference in the health outcome for the infant.","However, specificity and sensitivity are considerably diminished when they are applied to population surveys. All of the indicators available at the present time are affected by factors other than ID that may remain undetected in random samples ( Table 1) . Levels may not accurately reflect iron status in the presence of infection, inflammation, and liver disease.",[1],Medicine,train,1.0,news,http://guardianlv.com/2014/04/newborn-iron-deficiency-unlocked/
10.1073/pnas.1214971109,Medicine_easy_183,"He also wants to explore ""trigels"" and other ""polygels.""","Instead, we note that the behavior of the SW + HS system is very similar to that of 1CM gels.","""We could apply these methods to a wealth of materials other than gels, foams or inks,"" says Giuseppe Foffi. To explore this new area, the researcher must expand from the micro- to the nanometric level. He also wants to explore ""trigels"" and other ""polygels.""","We can conclude that such differences are due to general steric effects and not to the interpenetrating nature of the two subgels. Instead, we note that the behavior of the SW + HS system is very similar to that of 1CM gels. In our case, it is directly related to the porosity of the gel, as already pointed out for dipolar colloidal gels .",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2012/11/121105161212.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aaf2654,Medicine_easy_184,"Because they are not calculating the trajectory for the stationary fire truck, only for objects in motion (like pedestrians or bicyclists), they can't react quickly to register a previously stationary object as an object in motion.",Moral algorithms for AVs will need to tackle more intricate decisions than that we have considered in our surveys.,"GPS is vulnerable

GPS hacking is a very real danger for autonomous vehicles. An autonomous car can't see the fire truck if the fire truck suddenly pulls out into traffic. Because they are not calculating the trajectory for the stationary fire truck, only for objects in motion (like pedestrians or bicyclists), they can't react quickly to register a previously stationary object as an object in motion.","This is a challenge that should be on the mind of carmakers and regulators alike. Moral algorithms for AVs will need to tackle more intricate decisions than that we have considered in our surveys. For example, our scenarios did not feature any uncertainty about decision outcomes, but a collective discussion about moral algorithms will have to tackle the concepts of expected risk, expected value, and blame assignment.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33605351341&p=1pl&v=1&x=N74a4B-zhUSTmdqZK1LTkg
10.1038/nrg2703,Medicine_easy_186,"It just takes one grain to fertilize the female part of a plant, so casting fate to the wind isn't a bad strategy.","In sharks, a 'switch' at the biochemical level from multimeric to monomeric IgM provides at least some of the functions of an IgG -for example, the capacity to enter extravascular sites -and an increase in affinity, but the memory response is clearly inferior to that of the higher vertebrates.","MacGregor Campbell/OPB

It helps to know a little bit about why pollen exists in the first place. It just takes one grain to fertilize the female part of a plant, so casting fate to the wind isn't a bad strategy. ""It's remarkable that something so random actually ends up working,"" Jones said.","There is no switching apparent between clusters in cartilaginous fish, neither within the IgM class nor between the IgM and cartilaginous fish-specific IgnAR/IgW classes. In sharks, a 'switch' at the biochemical level from multimeric to monomeric IgM provides at least some of the functions of an IgG -for example, the capacity to enter extravascular sites -and an increase in affinity, but the memory response is clearly inferior to that of the higher vertebrates. T cells develop in the thymus, and the basic evolution of the thymus and T cell development is conserved for all gnathostomes, except in some species in which the system seems to have degenerated (FIG.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34307692391&p=1pl&v=1&x=mm-osFSBw9YRNm7JQuxdew
10.1377/hlthaff.2012.1030,Medicine_easy_187,"The variation among small and rural hospitals ""may be driven in part by the overall volume of deliveries,"" but none of the factors appeared to explain much of the overall variation, Kozhimannil's group pointed out.","Such triage could take the form of high-risk hospitals with the capacity to manage extremely complex patients alongside obstetric care settings, such as licensed birth centers, which focus on physiologic childbirth for lower-risk women.","Again, ranges were somewhat greater at small and rural hospitals but less among teaching hospitals. The variation among small and rural hospitals ""may be driven in part by the overall volume of deliveries,"" but none of the factors appeared to explain much of the overall variation, Kozhimannil's group pointed out. Women asking for C-sections accounts for too small a percentage of these deliveries to drive the variations either, they argued.","In the context of childbirth, better care coordination could include more effective riskbased triage for maternity care. Such triage could take the form of high-risk hospitals with the capacity to manage extremely complex patients alongside obstetric care settings, such as licensed birth centers, which focus on physiologic childbirth for lower-risk women. 36 Better triage may reduce overall cesarean rates, but some rate variation across facilities would remain, although this would be by design rather than happenstance.",[1],Medicine,train,1.0,news,http://abcnews.go.com/Health/section-rates-vary-widely-hospitals-study-finds/story?id=18656847
10.1016/j.jamcollsurg.2014.12.012,Medicine_easy_188,This new study validates the accuracy of their predictive model.,"16 Once complications occur and urgent hospitalization and/or cholecystectomy is necessary, the morbidity and mortality are significantly increased.","Dr. Taylor Riall, professor of surgery at UTMB and lead author of the study, said that even though gallbladder removal is recommended for patients with gallstone problems, ""Less than a quarter of patients in this study had their gallbladders removed. This new study validates the accuracy of their predictive model. Among those who did not have their gallbladder removed, less than 20 percent in the low-risk group ended up being hospitalized for gallbladder-related issues -- for the high-risk group, 65 percent were hospitalized within two years of first symptoms.","14 This might be due to the increased morbidity and mortality of elective cholecystectomy in older patients. 16 Once complications occur and urgent hospitalization and/or cholecystectomy is necessary, the morbidity and mortality are significantly increased. 14 Although the data demonstrate that fewer than one quarter of older patients with symptomatic gallstones undergo elective cholecysetctomy, 14 it is not known if current decisions about elective cholecystectomy in this population are based on risk.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141223191727.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1186/1472-6785-14-4,Medicine_easy_189,The study discovered 79 slugs were exposed to over a million fluorescently tagged worms.,"Our sampling scheme did not allow us to evaluate these alternatives, because sampling depth was kept constant at up to 15 cm over the 18 month-period to ensure comparability of sampling results across time.","The study discovered 79 slugs were exposed to over a million fluorescently tagged worms. ""Our study reveals a previously unknown nematode lifestyle within the guts of slugs,"" said lead researcher Dr. Hinrich Schulenburg. According to Schulenburg, the worms seem to have evolved, persisting in the harsh environment inside the intestines of slugs.","It is possible that during winter the nematodes move to deeper compost layers with more favourable temperatures or die out in these substrates, followed by recolonization in spring or summer. Our sampling scheme did not allow us to evaluate these alternatives, because sampling depth was kept constant at up to 15 cm over the 18 month-period to ensure comparability of sampling results across time. Humidity and rain were additionally expected to affect Caenorhabditis distributions.",[1],Medicine,train,1.0,news,http://www.techtimes.com/articles/68382/20150714/worms-hitchhike-with-slugs-to-reach-far-places.htm
10.1016/j.cmet.2015.02.003,Medicine_easy_190,"MORE Older Adults May Be OK to Eat More Salt Than Previously Thought

The discovery came about by accident, after Jens Titze, the study's senior author, noticed that mice who had been bitten by their cage mates showed higher levels of sodium in their skin than those who were wound-free.","Similarly, HS augmented NO release in peritoneal MF ( Figure S1A ).","Salt, it seems, may be an ancient way for the body to protect itself against bacteria. MORE Older Adults May Be OK to Eat More Salt Than Previously Thought

The discovery came about by accident, after Jens Titze, the study's senior author, noticed that mice who had been bitten by their cage mates showed higher levels of sodium in their skin than those who were wound-free. The mice fed the higher amounts of sodium showed stronger immune responses to the wounds, and cleared their infections faster than the mice eating less salt.","Parallel experiments with increased concentrations of the tonicity control, urea, (Table S1 ) neither increased Nos2 expression nor NO release ( Figure 2A ). Similarly, HS augmented NO release in peritoneal MF ( Figure S1A ). In line with earlier data , HS boosted LPS-induced TNF secretion in MF (Figures S1B and S1C).",[1],Medicine,train,1.0,news,http://time.com/3730061/the-weird-benefit-of-eating-salty-food/
10.1177/0956797617692041,Medicine_easy_192,The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving.,"Their mean age was 30.05 years (SD = 12.30), and the sample was 38.9% White, 23.5% Black, 23.2% Asian, 5.6% Hispanic, 4.9% Pacific Islander, 2.5% mixed race, and 0.3% American Indian; 1.1% did not report their race.","The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means. The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving. However, it did not affect the further downstream behavior of consumption.","Of 285 participants, 48.4% were male and 50.5% were female; 1.1% did not report their gender. Their mean age was 30.05 years (SD = 12.30), and the sample was 38.9% White, 23.5% Black, 23.2% Asian, 5.6% Hispanic, 4.9% Pacific Islander, 2.5% mixed race, and 0.3% American Indian; 1.1% did not report their race. This was done because we were primarily interested in refill behavior as a function of service style, and allowing the participants to buy drinks substantially increases the required sample size (because only 60% of participants typically buy drinks).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1038/s41467-019-09863-x,Medicine_easy_193,"The research team say they hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios, and help guide policy-makers towards prudent decisions on emissions reduction targets.","First, the PAGE-ICE model, in common with other aggregate IAMs, does not explicitly model other known climatic tipping elements such as Amazon rainforest, boreal forest, coral reefs and El Niño-Southern Oscillation (ENSO), as well as ocean acidification and climate-induced large-scale migration and conflict 62 (we cannot reject the null hypothesis that the total economic effects of climate change are the same for these scenarios either at the 5% or at the 10% significance level).","The increases, according to the study, occur primarily through temperature-driven impacts on the economy, ecosystem, human health and additional impacts from seal level rise. The research team say they hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios, and help guide policy-makers towards prudent decisions on emissions reduction targets. ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C,"" Yumashev said.","6) , we have several reasons to believe it would be prudent to aim for emissions towards the bottom end of the range covered by these scenarios. First, the PAGE-ICE model, in common with other aggregate IAMs, does not explicitly model other known climatic tipping elements such as Amazon rainforest, boreal forest, coral reefs and El Niño-Southern Oscillation (ENSO), as well as ocean acidification and climate-induced large-scale migration and conflict 62 (we cannot reject the null hypothesis that the total economic effects of climate change are the same for these scenarios either at the 5% or at the 10% significance level). Some of these effects are already included implicitly in the highly uncertain non-economic and discontinuity impact sectors in PAGE-ICE, contributing to the long upper tails in the distributions of the total economic effect of climate change in Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39075144927&p=1pl&v=1&x=7hu8D2B6RjJADdTPIfJdLQ
10.1038/s41467-018-08278-4,Medicine_easy_194,"Zwar ist die Studie nur ein kleiner Schritt, sie konnte aber zu einem grossem Fortschritt bei der Behandlung von Erkrankungen wie Arthrose fuhren.",We show here that Bmp9 is transiently expressed during digit joint cavitation and that BMP9 treatment stimulates joint regeneration.,"Das konnte Sie auch interessieren

Trotz Regeln floss bei den brutalen Ritterspielen viel Blut

Die Nasa hat auf dem Neptun einen ,,dunklen Wirbelsturm"" entdeckt, der 20 Prozent der Erdoberflache schlucken wurde

Die Regeneration von Knochen wurde auch fruher erreicht, aber ohne das zusatzliche Protein wurden die Knochen zum Beispiel nach einer Fraktur zusammenwachsen, anstatt Gelenk- und Knorpelgewebe zu vergrossern. Zwar ist die Studie nur ein kleiner Schritt, sie konnte aber zu einem grossem Fortschritt bei der Behandlung von Erkrankungen wie Arthrose fuhren. Denn sie konnte den Ersatz von Knorpel durch die korpereigenen Zellen eines Menschen ermoglichen, anstatt sich auf Transplantate verlassen zu mussen.","Unlike other BMP family members, BMP9 is not effected by BMP antagonists such as Noggin 12 which suppresses BMP signaling and is necessary for joint morphogenesis . We show here that Bmp9 is transiently expressed during digit joint cavitation and that BMP9 treatment stimulates joint regeneration. During angiogenesis, BMP9 acts in a contextdependent manner, inhibiting neovascularization in a model of age-related macular degeneration , while stimulating angiogenesis associated with induced osteogenesis .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38488446029&p=1pl&v=1&x=pEPzQn-OGtRw5F4FBoLIWA
10.1073/pnas.1403984111,Medicine_easy_195,"In this way, he showed that almost all the ivory that's been seized in the last decade has come from just two poaching hotspots--one that includes Gabon and the Congo, and another centered in Tanzania.","The repercussions of this harvest when driven by illegal commercial trade are not only ecological in nature, but raise human health (6) and socioeconomic concerns (2, 7) with broad implications for national and international policy and security .","In this way, he showed that almost all the ivory that's been seized in the last decade has come from just two poaching hotspots--one that includes Gabon and the Congo, and another centered in Tanzania. So, rather than targeting poachers, he says, it's far more efficient to go after their customers. It's likely that these same cartels are funding poachers in the first place.","Further, our approach provides a powerful basis to determine cryptic mortality and gain understanding of the demography of at-risk species. The repercussions of this harvest when driven by illegal commercial trade are not only ecological in nature, but raise human health (6) and socioeconomic concerns (2, 7) with broad implications for national and international policy and security . This monitoring system provides powerful data regarding the site-specific relative causes of mortality [i.e., the proportion of illegally killed elephants (PIKE)] that has served to indicate regional levels of illegal harvest .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37151262070&p=1pl&v=1&x=2kcAbHXpIqOOjL4ptCVntA
10.1073/pnas.1403984111,Medicine_easy_196,The numbers are also quite similar to other estimates from wildlife conservation groups.,"The three regions of Africa (Central, East, and Southern) demonstrated different trends that were captured by both approaches.","The scrutiny we did internally was at a much greater level than the questions we got in the peer review process."" The numbers are also quite similar to other estimates from wildlife conservation groups. Others put the number significantly lower, i.e.","Illegal killing rates were estimated to average ∼6.8% between 2010 and 2012, equating to an average of ∼33,630 elephants killed per y based on current estimates of the species total (24) ( Table 1 ). The three regions of Africa (Central, East, and Southern) demonstrated different trends that were captured by both approaches. Illegal killing was most pervasive in the populations of Central Africa (Figs.",[1],Medicine,train,1.0,news,http://www.theepochtimes.com/n3/898205-20-of-all-african-elephants-killed-in-3-years/
10.1038/s41467-018-04906-1,Medicine_easy_197,"If the user's temperature isn't within the required limits, the fingerprint authentication might not push through.","However, these large open areas can significantly increase the resistance of AgNF networks when they are patterned as fine electrodes with narrow widths because locally disconnected areas are produced by etching AgNFs.","Although this sounds like a neat feature that can thwart spoofing, the downside here is if users are colder than usual due to environmental reasons. If the user's temperature isn't within the required limits, the fingerprint authentication might not push through. ""These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending.","This thermal annealing step did not break the AgNFs, and the single fibers were long enough to minimize the number of junctions between onedimensional metallic geometries, which leads to a significant reduction of R s while maintaining large open spaces in the networks for high transmittance. However, these large open areas can significantly increase the resistance of AgNF networks when they are patterned as fine electrodes with narrow widths because locally disconnected areas are produced by etching AgNFs. For these narrow patterns such as the bottom electrodes (width: 65 μm, space: 15 μm) of the fingerprint sensors and the source (S)/drain (D) (width: 15 μm) of pressure-sensitive FETs, random networks of AgNWs (average length of AgNWs: 30 ± 7 μm, diameter: 20 ± 5 nm) were successively electrosprayed on top of the electrospun AgNF networks using a suspension of AgNWs (B 424-1, Nanopyxis) and a nozzle (nozzle inner diameter: 0.64 mm).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1073/pnas.1214971109,Medicine_easy_200,"He also wants to explore ""trigels"" and other ""polygels.""","Clearly, the interplay between the fluctuations in composition and in density gives rise to the different percolation regimes.","""We could apply these methods to a wealth of materials other than gels, foams or inks,"" says Giuseppe Foffi. To explore this new area, the researcher must expand from the micro- to the nanometric level. He also wants to explore ""trigels"" and other ""polygels.""","The nature of the percolation at the simulated state points closely reflects the TPT calculations. Clearly, the interplay between the fluctuations in composition and in density gives rise to the different percolation regimes. When the c fluctuations prevail, both the components tend to percolate, whereas only one component percolates when density fluctuations dominate.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2012/11/121105161212.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamapsychiatry.2015.0500,Medicine_easy_201,"Boys were more likely than girls to be prescribed these drugs, and the researchers were encouraged that, overall, antipsychotic use among children has slightly dropped from 2008 to 2010.",35 This normal maturation of neurobiological systems may underlie the decrease in antipsychotic treatment prevalence during late adolescence among youth who do not have enduring cognitive impairments and long-term severe behavioral disorders.,"""What's especially important is the finding that around 1.5 percent of boys aged 10-18 are on antipsychotics, and then this rate abruptly falls by half, as adolescents become young adults."" Boys were more likely than girls to be prescribed these drugs, and the researchers were encouraged that, overall, antipsychotic use among children has slightly dropped from 2008 to 2010. (The average rates of use hover around 1 percent of the population)

Regardless, they were concerned about the fact that these drugs were usually given by medical professionals without efforts to seek safer, more appropriate, treatments or for conditions that are known to improve over age.",Much also remains to be learned about the community and clinical prevalence of explosive aggression in children and adolescents. 35 This normal maturation of neurobiological systems may underlie the decrease in antipsychotic treatment prevalence during late adolescence among youth who do not have enduring cognitive impairments and long-term severe behavioral disorders. Social factors may also play a role in the age-related decrease in antipsychotic treatment in late adolescence.,[1],Medicine,train,1.0,news,http://www.medicaldaily.com/antipsychotics-are-being-given-kids-temporary-behavioral-problems-adhd-341188
10.1016/j.cell.2015.07.058,Medicine_easy_203,"""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea.",Etoposide induces cellular DNA breaks and the phosphorylation of ATM at discrete DDR foci ( Figure 3C ).,"This means the virus is effectively ignored while the cell responds to the more massive alarm. ""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","ATM activation triggers ATM autophosphorylation at Ser1981 . Etoposide induces cellular DNA breaks and the phosphorylation of ATM at discrete DDR foci ( Figure 3C ). Strikingly, ATM phosphorylation is also induced at nascent E2A viral genome replication domains ( Figure 3D ).",[1],Medicine,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/s41598-018-26198-7,Medicine_easy_204,"""Because INF-g is one of the key effector cytokines in cytotoxic immune responses, these results support a role for stretching in promoting TH-1 cytotoxic immunity,"" they note.","Both active and passive stretching had similar effects compared with anesthesia alone, and there was no significant difference between the effects of active and passive stretching 23 .","The authors point out that diminished cytotoxic immunity is a mechanism that underpins the state of T-cell exhaustion in cancer, and is linked with lower levels of effector cytokines and the presence of inhibitor receptors on T cells, which permits tolerance to the cancer cells. ""Because INF-g is one of the key effector cytokines in cytotoxic immune responses, these results support a role for stretching in promoting TH-1 cytotoxic immunity,"" they note. When they next looked at T-lymphocyte populations, they found that mice in the stretch group exhibited lower levels of programmed death receptor-1 (PD-1) checkpoint-bearing CD8+ T cells, one of the major markers of T-cell exhaustion, suggesting that stretching may in addition counteract CD8+ T-cell impairment and ""allow adaptive cytotoxic immune responses against the tumor to take place.""","While our method of stretching does not fully suspend the animal, since its front feet are allowed to grip a bar of the cage, some stress inevitably results from being restrained by the tail, and muscle activity is required to maintain the stretched posture; in the no stretch group, we did not hold the mice by the tail, as they have a tendency to pull away which can cause inadvertent stretching of tissues. Both active and passive stretching had similar effects compared with anesthesia alone, and there was no significant difference between the effects of active and passive stretching 23 . This result demonstrated a mechanical effect of stretching that was not due to stress or muscle activity (since these were identical in the two anesthetized groups).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34125675804&p=1pl&v=1&x=EIuTbzUDbEKkr7kvXb-kdg
10.1002/ece3.3060,Medicine_easy_206,"""Even though some habitat features seemed to affect dispersal, we found that, for all four species, breeding season was a better predictor than habitat of the observed genetic differences,"" Burkhart says.","Although metamorphosis is often prolonged, under stressful environmental conditions, such as pond drying, amphibian larvae are able to initiate metamorphosis more quickly if individuals are larger than the threshold size for metamorphosis .","Distance between ponds and various landscape features could not fully explain the observed genetic differences. ""Even though some habitat features seemed to affect dispersal, we found that, for all four species, breeding season was a better predictor than habitat of the observed genetic differences,"" Burkhart says. ""Practically, what this says is that landscape variables are not quite as important as the timing of the breeding season.""","We observed higher degrees of genetic differentiation and the presence of genetic clusters for the fall breeding species, A. annulatum and A. opacum, and a lower degree of genetic differentiation and a lack of genetic clustering in the spring breeding species, A. maculatum and N. v. louisianensis. Although metamorphosis is often prolonged, under stressful environmental conditions, such as pond drying, amphibian larvae are able to initiate metamorphosis more quickly if individuals are larger than the threshold size for metamorphosis . Our observation of differential patterns of genetic structure between spring and fall breeding salamander species concurs with previous genetic studies of ambystomatid species that investigated patterns of genetic differentiations in species with different life histories.",[1],Medicine,train,1.0,news,http://www.futurity.org/salamanders-breeding-1515412-2/
10.1038/s41598-018-35253-2,Medicine_easy_207,"If this volcano and glacier is representative of other similar systems, it could mean masses of previously unaccounted methane are being released into the atmosphere.",Signatures of mixed geogenic/microbial origin should therefore lie on an end member mixing trajectory as depicted in Fig.,"The study, published in Scientific Reports, is the first to show methane is released from glaciers on such a large scale. If this volcano and glacier is representative of other similar systems, it could mean masses of previously unaccounted methane are being released into the atmosphere. They found that compared to other nearby rivers and sediments, the levels were far higher.","Isotopic fractionation during biogenic methanogenesis typically leads to δ 13 C values between −50 to −110‰, and δD values between −170 to −531‰ 23 . Signatures of mixed geogenic/microbial origin should therefore lie on an end member mixing trajectory as depicted in Fig. As the most enriched values exceed the geogenic range, the observed isotopic signatures cannot be explained by a mixture of biogenic and geogenic methane (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37747037897&p=1pl&v=1&x=25zujygYqDoju4-7l9c6zQ
10.1016/j.cub.2018.06.016,Medicine_easy_208,"Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting.","There were no sex differences in the percentage of time spent in motion ( Figure S1D ; p = 0.630), suggesting that sex differences are specific to social engagement.","As the project progressed, fish were exposed to non-fish objects, which failed to initiate social orienting. Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting. The presence of another fish that is not socially engaged is insufficient to trigger interaction regardless of their proximity, a finding that mirrors reciprocal social interaction in humans.","These findings replicate previous descriptions of sex differences in zebrafish social behavior . There were no sex differences in the percentage of time spent in motion ( Figure S1D ; p = 0.630), suggesting that sex differences are specific to social engagement. Consistent with mammalian studies, apo-treated fish had impaired social interactions and showed no significant increase in time spent at 45 -90 when exposed to control fish ( Figure 1F ; p = 0.260, 2446 Current Biology 28, 2445-2451, August 6, 2018 n = 23).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34657319504&p=1pl&v=1&x=IZljwk13voqosD3secxjLg
10.1176/appi.ajp.2018.17111282,Medicine_easy_209,"Ultimately, we're all interested in making medication more efficient.","A pilot study in 58 inpatients participating in the MARS project found that subjects whose ABCB1 genotyping information was used in clinical decision making had greater HAM-D response rates (t=2.091, df=111, p=0.020, one-sided) and greater remission rates (x 2 =6.596, df=1, p=0.005, one sided) .","It's simply too early. Ultimately, we're all interested in making medication more efficient. But even though products promising a future filled with personalized medicine are starting to hit drugstore shelves, the research still suggests we're not at a point where our genes can help determine our dosages -- yet.","Further obscuring the evaluation of this approach is the finding that some antidepressants modulate the activity of ABCB1 itself . A pilot study in 58 inpatients participating in the MARS project found that subjects whose ABCB1 genotyping information was used in clinical decision making had greater HAM-D response rates (t=2.091, df=111, p=0.020, one-sided) and greater remission rates (x 2 =6.596, df=1, p=0.005, one sided) . Inclusion of ABCB1 here is not based on the level of evidence supporting its association with the treatment of major depression but rather because the study described above that investigated the clinical utility of ABCB1-guided treatment falls within the purview of this review.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1073/pnas.1414221111,Medicine_easy_211,Planning has begun to move (+)-SJ733 from the laboratory into the clinic beginning with a safety study of the drug in healthy adults.,"Therefore, (+)-SJ733 is expected to have a safety margin of at least 43-fold [comparing AUC max in the rat safety studies to AUC from the dose giving maximal parasitological response in mice (Fig.","""The data suggest that compounds targeting ATP4 induce physical changes in the infected red blood cells that allow the immune system or erythrocyte quality control mechanisms to recognize and rapidly eliminate infected cells,"" DeRisi said. ""This rapid clearance response depends on the presence of both the parasite and the investigational drug. Planning has begun to move (+)-SJ733 from the laboratory into the clinic beginning with a safety study of the drug in healthy adults.","(+)-SJ733 has not exhibited either significant safety liabilities at any dose in extensive profiling in vitro (see summary in SI Appendix) or significant safety or tolerability liabilities in either single-or repeat-dose studies at any dose tested in any preclinical species (no observed adverse effect level and maximum tolerated dose >240 mg/kg from 7-d repeat dosing study in rat; see summary in SI Appendix). Therefore, (+)-SJ733 is expected to have a safety margin of at least 43-fold [comparing AUC max in the rat safety studies to AUC from the dose giving maximal parasitological response in mice (Fig. 1C) ].",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1038/s41598-017-03627-7,Medicine_easy_212,"There's more research to be done, for instance, focusing on clinical implications of these findings and even implications of empathy training.",It is thus possible that males did not realize the magnitude of the effectiveness of their touch and therefore their pain ratings did not decrease in the touch condition.,"However, this current study acknowledges that mechanisms identified as social touch analgesia (pain-relief without loss of consciousness), remains widely unknown. There's more research to be done, for instance, focusing on clinical implications of these findings and even implications of empathy training. According to Goldstein, ""it's unlikely that this research will solve the problem of painkillers.""","These findings can be explained by the fact that female participants experienced the real pain and their male partners only guessed the females' pain level. It is thus possible that males did not realize the magnitude of the effectiveness of their touch and therefore their pain ratings did not decrease in the touch condition. Although the current study used a controlled design with several balanced conditions, it has several limitations that need to be acknowledged.",[1],Medicine,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1126/science.aan2802,Medicine_easy_213,"""When you can split a true surface Dirac cone while keeping time-reversal symmetry, something truly special happens,"" said Bernevig.","12(d,f) , pristine Au 2 Y 3 and Hg 2 Sr 3 are gapless, with C 4z -protected Dirac points near the Fermi energy.","""This allows an elegant and immediately useful means of designing desirable surface and interface states."" ""When you can split a true surface Dirac cone while keeping time-reversal symmetry, something truly special happens,"" said Bernevig. ""If we could paint these materials with the right wallpaper, we'd see more Dirac insulators,"" said Wieder, ""but sometimes, the wrong wallpaper is interesting too.""","We find that Sr 2 Pb 3 posses an indirect gap but that, as shown in Fig. 12(d,f) , pristine Au 2 Y 3 and Hg 2 Sr 3 are gapless, with C 4z -protected Dirac points near the Fermi energy. Applying strain in the (100)-direction (x) breaks C 4z while still preserving the two glides that project to form wallpaper group pgg on the (001)-surface.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34589828281&p=1pl&v=1&x=ORfbQynOxQU3ku30qRz59A
10.1016/j.celrep.2016.08.013,Medicine_easy_214,"""Our in vitro live-cell-imaging-based system will permit more efficient dissection of the underlying interaction mechanisms and more rapid screening for inhibitors of bacterial-endothelial interactions and dissemination.""",Tethers and catch bonds can independently stabilize leukocyte rolling under lower shear stress conditions but act together to strengthen interactions at higher shear stresses.,"The study appears August 25 in Cell Reports. ""Our in vitro live-cell-imaging-based system will permit more efficient dissection of the underlying interaction mechanisms and more rapid screening for inhibitors of bacterial-endothelial interactions and dissemination."" By calculating the displacement of bacteria from the endothelial cells, the researchers also found that the microbes use bungee-cord-like tethers to stabilize and strengthen these bonds.","Interaction of circulating cells with endothelia is not stabilized by catch bonds alone, but also by tension-responsive, stretch-able cellular and extracellular structures physically associated with adhesion complexes. Tethers and catch bonds can independently stabilize leukocyte rolling under lower shear stress conditions but act together to strengthen interactions at higher shear stresses. B. burgdorferi extravasate extremely rapidly from PCVs (<150 ms to penetrate endothelial lining) in a process that does not require bacterial stationary adhesion and is initiated by two mechanistically distinct interaction types, tethering and dragging, which move faster and slower than 100 μm/s, respectively, along PCV surfaces .",[1],Medicine,train,1.0,news,https://www.sciencedaily.com/releases/2016/08/160825130027.htm
10.1001/jama.2009.1943,Medicine_easy_215,You destroy the placebo effect if you destroy people's faith and trust in their doctors.,This important feature of the evidence base is not reflected in the implicit messages present in the marketing of these medications to practitioners and the public.,"No, because you'd have to lie to people, and I don't think patients should be lied to. You destroy the placebo effect if you destroy people's faith and trust in their doctors. It's unethical and ultimately self-defeating.","What makes our findings both surprising and compelling is the high level of depression symptom severity that appears to be required for clinically meaningful drug/placebo differences to emerge, particularly given the evidence that the majority of patients receiving antidepressant medication in clinical practice present with scores below these levels. This important feature of the evidence base is not reflected in the implicit messages present in the marketing of these medications to practitioners and the public. , efforts should be made to clarify to providers and prospective patients that whereas ADMs can be quite potent with more severe depressions, there is little evidence to suggest that they produce specific pharmacological benefit for the majority of patients with less severe depressions.",[1],Medicine,train,1.0,news,http://discovermagazine.com/2010/the-brain/09-psychologist-says-antidepressants-are-just-fancy-placebos?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+DiscoverMindBrain+%28Discover+Mind+%26+Brain%29
10.1002/emmm.201302567,Medicine_easy_216,"(click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults.",D. Western analysis shows reduction in SMN expression at PS7 and especially at PS30.,"Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views). (click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults. Hence the importance of the team's success, reported online today in EMBO Molecular Medicine.","RT-PCR shows inhibition of exon 7 inclusion in PS7 spinal cord (B) and other tissues (C). D. Western analysis shows reduction in SMN expression at PS7 and especially at PS30. www.embomolmed.org Post-developmental pathology in SMA displayed facial and paw oedema, culminating in death.",[1],Medicine,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1373/clinchem.2012.187617,Medicine_easy_217,Conducting a fecal study in space is harder than you think.,The advantages of using urinary samples include relatively large sample volumes and the convenience of noninvasive collection.,"Yes, that's poop, and in Scott Kelly's case, his space poop had a lot to say about life 240 miles above the planet's surface. Conducting a fecal study in space is harder than you think. While Scott Kelly was in orbit, the microbes found in his gut shifted significantly from the kinds that the researchers found on the ground.","The data set will enable future investigations into the epidemiology and ecology of the human microbiome in various disease states, and treatment strategies will evolve from these studies. The advantages of using urinary samples include relatively large sample volumes and the convenience of noninvasive collection. In addition, urine samples can be used for the investigation of the chronology of metabolic changes and thus are a valuable tool for investigations related to the pathogenesis or progression of disease and for screening and diagnosis as well as prognostic evaluation.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1038/s41598-018-30933-5,Medicine_easy_218,Krasheninnikova said the answer might lie in the way that African greys enjoy manipulating objects.,"When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff.","But the African greys, one in particular, often took the token. Krasheninnikova said the answer might lie in the way that African greys enjoy manipulating objects. ""We know they're very playful,"" she said.","These findings parallel earlier findings in primates and suggest that the parrots indeed attributed value to the tokens. When provided with a choice between a food or a token that could be exchanged for more preferred food, all four species inhibited their impulsive reactions and selected the token significantly more often than chance, thus maximising their payoff. They did so regardless of the value of the immediate gain, i.e., low (condition 1) or medium (condition 2).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37173365584&p=1pl&v=1&x=NJ_GBBnbEaGhqvCYXwBU-Q
10.1038/s41598-018-25573-8,Medicine_easy_219,The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature.,A surface charge property can be altered to prevent the aggregation of particles in biological media and to achieve prolonged circulation.,"The scientists had similar results when they used ovarian tumor samples taken directly from patients, showing that their chicken egg model provides a system for replicating human cancer. The tumor closely resembles cancer patient tumor and contains extracellular matrix as well as stromal cells and extensive vasculature. No significant damage to various organs in the chicken embryo occurred.","These characteristics point to attractive features of this animal model system. A surface charge property can be altered to prevent the aggregation of particles in biological media and to achieve prolonged circulation. These nanoparticles retain the advantageous features of MSNs described above and, in addition, they possess enhanced degradability.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34218407527&p=1pl&v=1&x=TZ9cA3HHZNB3jHckRRSErA
10.1038/s41551-018-0317-8,Medicine_easy_221,(DONs alleviated oxidative stress within 2 hours of incubation with affected kidney cells.),"M13 and partially folded DONs expose virus DNA in the blood, which can trigger immune surveillance or enzyme/protein interaction and subsequent liver sequestration 25 .",The accumulation of the nanostructures in both healthy and diseased kidneys provided an increased therapeutic effect compared with traditional AKI therapy. (DONs alleviated oxidative stress within 2 hours of incubation with affected kidney cells.) Improvement in AKI kidney function -- comparable with high-dose administration of the drug NAC -- was observed following the introduction of nanostructures.,"First, compared with M13 ssDNA and partially folded DONs, intact DONs are more compact structures without significant regions of DNA exposed to enzymes/proteins in the blood pool 42 . M13 and partially folded DONs expose virus DNA in the blood, which can trigger immune surveillance or enzyme/protein interaction and subsequent liver sequestration 25 . In contrast, fully folded DONs may elude unnecessary enzyme digestion due to their compact structures 22 .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37636191811&p=1pl&v=1&x=qc3pI9OOn-ja-gCCneNC8w
10.1111/cdev.12250,Medicine_easy_222,"Unlike their less popular peers, these kids were actively seeking high school fame.","This study found that a constellation of pseudomature behaviors in early adolescence predicted significant difficulties in social functioning up to 10 years later, in early adulthood.","The kids who ran their high schools at 13 tended to drink more, get into trouble more, have more sex, and importantly, sought out popularity. Unlike their less popular peers, these kids were actively seeking high school fame. And as the cohort got older, these mature behaviors got a forceful shove into full-blown recklessness.","***p < .001. close friendship competence in early adolescence, higher levels of pseudomature behavior at ages 13-15 predicted lower peer ratings of participants' close friendship competence in early adulthood. This study found that a constellation of pseudomature behaviors in early adolescence predicted significant difficulties in social functioning up to 10 years later, in early adulthood. The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.",[1],Medicine,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1002/emmm.201302567,Medicine_easy_223,Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood.,"However, this systemic treatment had no therapeutic benefit in adult mice that were first administered ASO-20-37 by ICV injection (Fig 6) .","People who have 2-3 copies (Type II SMA) make more protein and survive longer, but can never walk. Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood. The flaw in the protein's production is understood.","Its ability to correct splicing in the CNS or peripheral tissues correlated with phenotypic and histological amelioration in ASO-20-37-treated mice (Fig 6; Supporting Information Fig S5) . However, this systemic treatment had no therapeutic benefit in adult mice that were first administered ASO-20-37 by ICV injection (Fig 6) . This is similar to what we observed with neonatal mice sequentially treated with these ASOs ).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1086/649555,Medicine_easy_224,This lesson is instructive in thinking about why some pockets of America are overreacting to the threat of Ebola.,"Using the attack rate of ILI (students, 10%; faculty/ staff, 5%) along with the size of the community (students, 18,872; faculty/staff, 5871), we estimated that 1887 students and 300 faculty/staff may have had ILI during the outbreak.","This lesson is instructive in thinking about why some pockets of America are overreacting to the threat of Ebola. The chances that Ebola will infect any given American is incredibly, incredibly small. There have been four infections in the United States since the first case was diagnosed here last month.","No hospitalizations were reported among faculty/staff. Using the attack rate of ILI (students, 10%; faculty/ staff, 5%) along with the size of the community (students, 18,872; faculty/staff, 5871), we estimated that 1887 students and 300 faculty/staff may have had ILI during the outbreak. No deaths were reported among the University community.",[1],Medicine,train,1.0,news,http://www.theatlantic.com/health/archive/2014/10/why-outbreaks-breed-hysteria/381898/
10.1038/s41467-019-09863-x,Medicine_easy_225,"According to the study, this affects their impact on both the global climate and economy.",All this warrants their rigorous quantitative assessment.,"The paper says nearly all climate policy studies to date implied a constant SAF and zero PCF. According to the study, this affects their impact on both the global climate and economy. ""These two components are set to peak for global temperatures within the range covered by the Paris Agreement, but if the climate warms further, the summer and spring sea ice and land snow covers will retreat further north and the albedo feedback will actually weaken.""","PCF is caused by additional CO 2 and methane emissions from thawing permafrost, and SAF is mostly driven by increased solar absorption due to the decline of Arctic sea ice and land snow covers. All this warrants their rigorous quantitative assessment. The emulators allow one to study the entire parameter space, which is not possible with complex physical models, and also help establish dynamic links between highly specialized climate and economic models.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39075144927&p=1pl&v=1&x=7hu8D2B6RjJADdTPIfJdLQ
10.1073/pnas.1322295111,Medicine_easy_227,"In particular, the scientists think that the insula may become hyperactive in chronic gamblers, heightening their sense of confidence and motivation.","Comparing the target group against the lesion comparison group and healthy participants, subjective confidence did not vary significantly as a function of either winning streak length (F(4,184) = 0.25, p = .833) or losing streak length (F(4,184) = 1.61, p = .192).","The scientists believe that these results suggest where we might find some of the neural circuits that play a critical role in risky decision making. In particular, the scientists think that the insula may become hyperactive in chronic gamblers, heightening their sense of confidence and motivation. These findings may be useful for the development of future treatments for gambling addictions, provided we can specifically target insula activity through prescription drugs or psychological techniques such as meditation.","This gambler's fallacy effect did not vary across groups (main effect of Group: F(2,50) = 1.14, p = .327; Group x Run Length interaction F(8,200) = 0.56, p = .728) (see Fig. Comparing the target group against the lesion comparison group and healthy participants, subjective confidence did not vary significantly as a function of either winning streak length (F(4,184) = 0.25, p = .833) or losing streak length (F(4,184) = 1.61, p = .192). As such, there was no discernible 'hot hand' effect in our data (although see also Table S3 ).",[1],Medicine,train,1.0,news,http://arstechnica.com/science/2014/04/brain-damage-can-make-people-immune-to-the-gamblers-fallacy/
10.1098/rsos.171474,Medicine_easy_229,"""We must stop the glorification of violence in our society,"" he said.",This is among the first studies to test the effects of violent gaming on human aggression using a preregistered hypothesis-testing framework and the first to do so following the registered reports protocol.,"""The idea of these video games, they dehumanize individuals to have a game out of shooting individuals and others,"" McCarthy said. ""We must stop the glorification of violence in our society,"" he said. ""This includes the gruesome and grisly video games that are now commonplace.""","It is crucial that scientists conduct work with openness and rigour if we are to build a real understanding of the positive and negative dynamics and impacts of technology in people's lives . This is among the first studies to test the effects of violent gaming on human aggression using a preregistered hypothesis-testing framework and the first to do so following the registered reports protocol. The results provide confirmatory evidence that violent video game engagement, on balance, is not associated with observable variability in adolescents' aggressive behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882021759&p=1pl&v=1&x=WDSVA9_GGY2tcF2kX9kO8w
10.1186/s12916-017-0986-2,Medicine_easy_230,"Overall, 25 percent of the patients in the reviewed studies had some type of complication after surgery.",Conflicts regarding the abstracted data were resolved through discussion.,"""These factors could be targeted in the preoperative clinic, potentially leading to better outcomes for older adults undergoing elective surgery,"" she said. Overall, 25 percent of the patients in the reviewed studies had some type of complication after surgery. More information

More on surgery risks for older people is available at SeniorLiving.Org.","April 21, 2016) for potentially relevant studies. Conflicts regarding the abstracted data were resolved through discussion. Similar to the concept of the number needed to treat or number needed to harm, the NNF represents the number of patients who need to be followed in a prognostic study in order to see one outcome .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33000673455&p=1pl&v=1&x=ZUA80X35mG1U_VnPyqM0hw
10.1073/pnas.1403984111,Medicine_easy_231,"Elephant numbers in Tanzania's Selous Game Reserve dropped from 40,000 to 13,000 in the last three years alone.",Preliminary data from 2013 indicate overharvesting continued.,"""There are still healthy growing populations in parts of Africa - Botswana, for example. Elephant numbers in Tanzania's Selous Game Reserve dropped from 40,000 to 13,000 in the last three years alone. Remy de la Mauviniere/AP

The study found that Botswana and South Africa's elephant populations remained relatively stable during the three year period.","More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year. Preliminary data from 2013 indicate overharvesting continued. In contrast to the rest of Africa, our analysis corroborates that Central African forest elephants experienced decline throughout the last decade.",[1],Medicine,train,1.0,news,http://www.usnews.com/news/newsgram/articles/2014/08/19/poachers-exhausting-elephant-population
10.1186/2045-5380-3-19,Medicine_easy_232,It works by heightening CNS connections to control hyperactivity and impulses.,"FAAH inhibition also decreases anxiety in the rat pup ultrasonic vocalization test , light-dark exploration assay and marble-burying assay .","As such, the potential CBD shows as the most effective natural alternative to Adderall is very significant. It works by heightening CNS connections to control hyperactivity and impulses. This, in turn, helps improve focus and attention in those with ADHD.","For example, a CB1 receptor antagonist reduced anxiety in the elevated plus-maze in maze-experienced mice , reduced some signs of anxiety in the defensive probe burying assay and reduced anxiety associated with alcohol withdrawal . FAAH inhibition also decreases anxiety in the rat pup ultrasonic vocalization test , light-dark exploration assay and marble-burying assay . Similarly, FAAH−/− mice exhibit reduced anxiety in the light-dark box assay and elevated plus-maze during conditions of high aversiveness, but not low stress conditions .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1016/j.socscimed.2018.10.008,Medicine_easy_233,"Furthermore, women whose births had complications were 174% more likely to experience PND compared to those women who had no complications.","Newly adopting mothers also show similar levels of depression to postnatal women, indicating the importance of psychosocial stressors, in addition to biological factors, relating to early maternal experience .","Overall the researchers identified that women who give birth to males are 71-79% more likely to develop PND. Furthermore, women whose births had complications were 174% more likely to experience PND compared to those women who had no complications. As a result of their findings, Dr Sarah Johns and Dr Sarah Myers in the University's School of Anthropology and Conservation (SAC), conclude that recognising that both male infants and birth complications are PND risk factors should help health professionals in identifying and supporting women who may by more likely to develop this condition.","For instance, a broad-spectrum approach employing 74 inflammatory markers found inflammation to be the second best predictor of PND after prior depressive history . Newly adopting mothers also show similar levels of depression to postnatal women, indicating the importance of psychosocial stressors, in addition to biological factors, relating to early maternal experience . Significant ethical justification is rightly required before conducting biomedical tests on perinatal women, and while understanding causal pathways in depression aetiology is important, they are not necessarily needed to identify new risk factors.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37610791342&p=1pl&v=1&x=1tnqqzlDqElQHdC1h3TnYA
10.1038/s41598-018-29793-w,Medicine_easy_234,"As if that werenat weird enough, researchers further found that study participantsa noses fell into six different nasal microbiome subtypes.","Causality was not established in this study, but it seems possible that the increase in alpha-diversity was a result of the increased rhinorrhea rather than vice versa 36 .","Well, as a turns out, your nose has a microbiome, too a and it might play a key role in how well you fight off colds. As if that werenat weird enough, researchers further found that study participantsa noses fell into six different nasal microbiome subtypes. These nasal microbiome types are linked to how bad your cold symptoms get, and how well you fight the virus off in the first place.","The results of our study suggest that rhinovirus infection did not have a major impact on the microbiota, although we found an association between rhinorrhea severity and increased alpha-diversity after the virus challenge. Causality was not established in this study, but it seems possible that the increase in alpha-diversity was a result of the increased rhinorrhea rather than vice versa 36 . A convenience sample of patients with H1N1 type influenza found that during infection the microbial profile was similar to that described in healthy individuals and the profile had no correlation with the demographic characteristics of the patients 37 .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37227743738&p=1pl&v=1&x=2zyW9bON3VHP6zbXr8qTXQ
10.1038/s41467-018-08278-4,Medicine_easy_235,"Not only did the bones regrew, they also formed more complete joint structures with part of the new bones attached to them.",Prg4 expression is associated with synovial cavity formation during development.,"After three days, over 60 per cent of the stump bones formed a layer of cartilage, as seen in joints, at the end of the bones.The result was more effective when the team treated the wounds first with BMP2 and then BMP9 a week later. Not only did the bones regrew, they also formed more complete joint structures with part of the new bones attached to them. Although the method does not yet produce a full toe.","This suggests that the cavitation response plays a key role in the joint regeneration response. Prg4 expression is associated with synovial cavity formation during development. Thus, the cavitation requirement in joint regeneration may be linked to progenitor cells associated with Prg4-expressing superficial cells.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38471832747&p=1pl&v=1&x=OkXzmFMojF7uETOGt2qtkg
10.1007/s13524-014-0321-x,Medicine_easy_237,This fact can also in part explain why mean age of parents has increased.,These differences may be moderated by the welfare state.,"""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased. People see that parenthood is easier for older people and choose to have children later.","However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births. These differences may be moderated by the welfare state. The differences in outof-wedlock childbearing and public support to parents may result in greater differences in parental well-being by marital status in Britain than in Germany.",[1],Medicine,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1016/j.cub.2013.11.012,Medicine_easy_239,"Individuals without computer experience found it far more difficult to make finely controlled adjustments of the hand, especially when the hand was hidden.","Interestingly, non-computer users still have a broad generalization as their generalization is significantly larger than zero even at the largest angular separation of 180 (30.0% 6 6.9%; p < 0.001, one-sample t test).","Before the training period, migrant works who already had computer experience performed better than their computer-naive peers on all the tests. Individuals without computer experience found it far more difficult to make finely controlled adjustments of the hand, especially when the hand was hidden. But after just 2 weeks of training, migrant workers with no previous computer experience performed just as well as college students at using a computer mouse and applying that skill to other fine-motor hand skills, the team reports today in Current Biology.","However, the computer users, compared to the non-computer-user group, generalize much more into other directions [interaction effect F(8, 96) = 6.9, p < 0.0001; main effect on groups F(2, 24) = 12.5, p < 0.0001, two-way ANOVA; Figure 2B ]. Interestingly, non-computer users still have a broad generalization as their generalization is significantly larger than zero even at the largest angular separation of 180 (30.0% 6 6.9%; p < 0.001, one-sample t test). There is no difference between the computer group and the student group, suggesting that subjects of different ages behave similarly as long as they are computer users.",[1],Medicine,train,1.0,news,http://news.sciencemag.org/brain-behavior/2013/12/click-here-improve-your-motor-skills
10.1073/pnas.1720880115,Medicine_easy_240,"""Our evidence, which squares with emerging evidence including rocks in western Australia, suggests that the early Earth was capable of forming continental crust within 350 million years of the formation of the solar system,"" said Patrick Boehnke, the T.C.","This is in contrast to the Lu/Hf system, where precise knowledge of concordance is vital for an accurate ingrowth correction; we do not perform an ingrowth correction because of the low Rb/Sr ratios in apatites.","Continental crust is richer in essential minerals than younger volcanic rock, which would have made it significantly friendlier to supporting life. ""Our evidence, which squares with emerging evidence including rocks in western Australia, suggests that the early Earth was capable of forming continental crust within 350 million years of the formation of the solar system,"" said Patrick Boehnke, the T.C. ""This alters the classic view, that the crust was hot, dry and hellish for more than half a billion years after it formed.""","Because a Pb-Pb age of a discordant zircon is a lower limit on the crystallization age, our inferred Rb/Sr ratios are biased to be too low rather than too high. This is in contrast to the Lu/Hf system, where precise knowledge of concordance is vital for an accurate ingrowth correction; we do not perform an ingrowth correction because of the low Rb/Sr ratios in apatites. The advantages to this technique are that it is element specific and has very high sensitivity.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34221550085&p=1pl&v=1&x=yntfsQfpUvQ2r4IWPN7HkA
10.1038/s41598-018-25573-8,Medicine_easy_241,"The team had similar results when they used ovarian tumour samples taken directly from patients, showing that their chicken egg model provides a convenient system for replicating human cancer.",Kidney shape is altered and spleen shrank and could not be detected.,"The team had similar results when they used ovarian tumour samples taken directly from patients, showing that their chicken egg model provides a convenient system for replicating human cancer. This conclusion is supported by their detailed characterization of the tumour, demonstrating that it possesses all major cancer features. ""We were surprised when the tumour was formed in three days,"" says Tamanoi. ""","The color of liver, intestine and kidney was quite different. Kidney shape is altered and spleen shrank and could not be detected. These results suggest that free doxorubicin causes various adverse effect but that these side effect can be overcome by loading onto the nanoparticles.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34220579892&p=1pl&v=1&x=hyv7yBfI9spqaAdmPr3ViA
10.1038/nn.3635,Medicine_easy_242,"Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say.","Importantly, comparing the V1 and IT time course directly (Fig.","The approach will be useful for future studies elucidating other perceptual and cognitive processes,"" says Kriegeskorte, who was not part of the research team. Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say. It could also shed light on processes that underlie conditions such as memory disorders or dyslexia, and could benefit patients suffering from paralysis or neurodegenerative diseases.","The difference in peak-to-peak latency was significant (n = 16, signpermutation test, P = 0.016). Importantly, comparing the V1 and IT time course directly (Fig. 4d) , we found that MEG signals correlated more with V1 than with IT early (peak at 93 ms (79-102 ms)) and more with IT than with V1 later (peak at 284 ms (152-303 ms)).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jpain.2017.11.005,Medicine_easy_243,But needle insertions in specific points are a universal trait of the therapy.,The results are shown in Table 6 .,"If nothing else, acupuncture qualifies as a ""time-tested"" form of therapy. But needle insertions in specific points are a universal trait of the therapy. More from Tonic:

From the perspective of conventional medicine, a therapy doesn't ""work"" unless it both outperforms a placebo and does so via an identifiable ""mechanism of action.""","Trial-level and patient-level characteristics are found in Tables 4 and 5 , respectively. The results are shown in Table 6 . We did not find any obvious association between trial outcome and characteristics such as the style of acupuncture (Traditional or Western), use of fixed versus individualized point selection or the use of electrical stimulation.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38497695155&p=1pl&v=1&x=s_16A13LceP0QMt7V7o-QA
10.1038/srep01456,Medicine_easy_245,"It is a return to normal.""","Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection.","The return of bed bugs, Borel notes, ""isn't a fluke. It is a return to normal."" Not surprisingly, the bugs with traits that made them better able to survive in their new digs outlived their friends and family members who weren't as well suited for the urban lifestyle.","Moreover, among 21 field bed bug populations tested, 100% of populations were associated with at least two molecular mechanisms (not including LA-1 the reference population), implying the prevalent involvement of multiple mechanisms of pyrethroid resistance in the field bed bug populations. Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection. The target genes tested were successfully suppressed by RNAi (Fig.",[1],Medicine,train,1.0,news,http://www.businessinsider.com/bedbugs-are-evolving-into-nightmare-insects-2015-4
10.1038/s41586-018-0731-9,Medicine_easy_247,"He said:

GRAVITY allowed us to resolve the so-called 'broad line region' for the first time ever, and to observe the motion of gas clouds around the central black hole.",We clearly detect a velocity gradient (Fig.,"So with these optical telescopes and the GRAVITY instrument, the astronomers can now see into distant space more clearly. He said:

GRAVITY allowed us to resolve the so-called 'broad line region' for the first time ever, and to observe the motion of gas clouds around the central black hole. Our observations reveal that the gas clouds do whirl around the central black hole.","We reject the null hypothesis of zero differential phase at a significance of more than 5σ (Methods). We clearly detect a velocity gradient (Fig. By fitting a model with symmetric photo-centres on the red and blue sides of the line to all data, we determine a measured offset of Δx = ±(−9.5, 6.8) ± (1.6, 1.1) μas in right ascension and declination to the blue and red sides, which corresponds to a radial shift of about 0.03 pc (6,000 au).",[1],Medicine,train,1.0,news,https://earthsky.org/space/1st-close-up-look-supermassive-black-hole-3c273
10.1534/genetics.116.197285,Medicine_easy_249,"Suddenly, dreams of creating super mosquitoes to eradicate disease were alive again.","11, 2016; frequency, whereas for low c and high fitness costs the driver may not be able to invade at all.","Unckless said despite its promise, the approach ""more or less stalled out"" until two years ago when researchers in California incorporated CRISPR/Cas9 into their gene drive constructs. Suddenly, dreams of creating super mosquitoes to eradicate disease were alive again. ""That might include the CRISPR/Cas9 machinery but also a new gene that provides resistance to dengue fever in the mosquito, for example, so the two spread together.","Briefly, in scenarios with high cleavage rate and small fitness costs, the driver will usually fix even when introduced at low 2 . 11, 2016; frequency, whereas for low c and high fitness costs the driver may not be able to invade at all. Intermediate scenarios can give rise to equilibria that are usually unstable, but can be stable if c is small and fitness costs are low and recessive.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1038/s41598-018-29793-w,Medicine_easy_250,"Overall the results of the study suggest a role for the nasal microbiota in the modulation of immune response, viral load and symptoms of the common cold in otherwise healthy adults.","Anyhow, few differences between the clusters were detected.","Importantly, changes in the response were reflected in cold symptoms and showed that subjects with Corynebacterium/Alloiococcus nasal microbiota type had lower symptom scores than Staphylococcus or Pseudomonadaceae/Mixed types. Overall the results of the study suggest a role for the nasal microbiota in the modulation of immune response, viral load and symptoms of the common cold in otherwise healthy adults. Further research studies are required to fully elucidate the possibilities that changes in nasal microbiota could bring to the treatment of the common cold.","Overall the D0 cluster effect on total symptom scores did not reach statistical significance (P = 0.06). Anyhow, few differences between the clusters were detected. WURSS-21 score, including functional and symptom scores, was lower in Cor/All cluster compared to Staph (P = 0.031) and Ps/Mix clusters (P = 0.026) (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37212337515&p=1pl&v=1&x=vY8mG30zrZfedaap_KKw6g
10.1038/ncomms4999,Medicine_easy_251,The picosecond ringing time is just perfect for the most efficient reaction.,This is not observed.,"Any longer and the enzyme would simple oscillate forever: react, unreact, react, unreact, etc. The picosecond ringing time is just perfect for the most efficient reaction. Klaas Wynne, Chair in Chemical Physics at the University of Glasgow said: ""This research shows us that proteins have mechanical properties that are highly unexpected and geared towards maximising efficiency.","If the solvated-protein spectrum in the terahertz range were due to multiple localized modes, one would expect an inhomogeneous gaussian distribution of local-mode frequencies-reflecting different local masses and forces-giving rise to a broad overdamped spectrum. This is not observed. An alternative explanation for the observed signal is librations of individual amino acids.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140603092424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1002/hec.3070,Medicine_easy_252,A 20 per cent sales tax would raise annual costs per person by about $15 to $17.,"The overall corresponding reductions in body weight (presented in Table 8 ) are similar at sample means for low (around 0.43kg) and middle income households (around 0.5kg), but almost half (around 0.23 Kgs) for high income households.","Although both taxes would be regressive, representing a greater proportion of lower incomes than higher ones, the proposed rates would keep this effect mild, Dr Sharma said. A 20 per cent sales tax would raise annual costs per person by about $15 to $17. But in weight-loss terms, average consumption would drop by more than 10,000 kilojoules a quarter, with about one third of a kilo coming off on the scales.","Middle-income households have the strongest response (56.02%). The overall corresponding reductions in body weight (presented in Table 8 ) are similar at sample means for low (around 0.43kg) and middle income households (around 0.5kg), but almost half (around 0.23 Kgs) for high income households. This can mainly be attributed to differences in quantities consumed by income groups: for example, while high-income households respond more to the tax in percentage points for cordial and fruit drinks, they consume less of those beverages overall (see Table 1 ).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140617094037.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.171474,Medicine_easy_253,"Mass shooters killed 31 people last weekend in El Paso and Dayton, Ohio, and three people in Gilroy, California, last month, including two children.","smaller), equivalent (i.e.","Mass shooters killed 31 people last weekend in El Paso and Dayton, Ohio, and three people in Gilroy, California, last month, including two children. The week was the deadliest for mass shootings and fatalities this year, whichever way one chooses to count them. Based on what their analyses revealed, here are five common misconceptions about the perpetrators of mass shootings:

Myth: Mass shooters have a specific profile that can be easily spotted ahead of time.","These results did not support the idea that there is a critical amount of violent video game play which serves as a tipping point for aggressive behaviour. smaller), equivalent (i.e. larger) to findings present in the existing literature , and in line with proposed minimum practical media effect sizes [72] .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882736616&p=1pl&v=1&x=QLA1HMQhScCizGL1drmq5A
10.1038/s41467-018-07459-5,Medicine_easy_254,"In other words, the authors think that there may be some follicle shapes out there that trap bacteria and oils more easily, causing breakouts to occur more often and with greater severity.",The binding site harbours a conserved sequence motif that is disrupted by rs34560261 (Fig.,"""It may be that the genetic variation influences the shape of these hair follicles and makes them more prone to bacteria and inflammation, which are a characteristic of acne."" In other words, the authors think that there may be some follicle shapes out there that trap bacteria and oils more easily, causing breakouts to occur more often and with greater severity. The authors note in the study that there appear to be plenty of gene regions yet to be identified by future research, but this is a terrific step forward.","The second putative causal variant identified by the finemapping approach is rs34560261, located in intron 1 of SEMA4B at 15q26.1. The binding site harbours a conserved sequence motif that is disrupted by rs34560261 (Fig. The protective minor allele introduces a thymine nucleotide at the position of an invariant cytosine (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37979673685&p=1pl&v=1&x=PH6n9y5vtIx8fZldCwwgSw
10.1126/science.1222939,Medicine_easy_255,"Still, the experts said esketamine has some important negative side effects and limitations.",3) (39) .,"They also said they believed esketamine's benefits outweighed its risks. Still, the experts said esketamine has some important negative side effects and limitations. And upon careful review, they felt Johnson & Johnson's new drug met the criteria to become one of those treatments, Farchione added.","An excess of GSK3-deconsolidation could contribute to the reduction in spine synapses in response to stress and depression (Fig. 3) (39) . Levels of GSK3 activity in the nucleus accumbens are also associated with social defeat stress, and blockade of GSK3 in this brain region or in response to systemic administration of a GSK3 inhibitor produces antidepressant effects in behavioral models of depression (39, 40) .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38698437603&p=1pl&v=1&x=wF8FpTPjqDBWQD9Nqv4Ddg
10.1038/s41598-018-29793-w,Medicine_easy_256,The discovery surprised even the longtime cold researchers who made it.,"Furthermore, oral probiotic consumption did not have an effect on nasal or fecal microbiota composition.","The compositions also were found to correlate with viral load -- the amount of cold virus inside the body. The discovery surprised even the longtime cold researchers who made it. ""The first surprise was that you can kind of identify these different buckets that people kind of fit into, and then the fact that the buckets seem to have some impact on how you respond to the virus and how sick you get was also interesting,"" said Ronald B. Turner, MD, of the University of Virginia School of Medicine.","We further found that rhinovirus infection did not have a major impact on the nasal microbiota. Furthermore, oral probiotic consumption did not have an effect on nasal or fecal microbiota composition. The results of this study raise the possibility that the modulation of the nasal microbiota, perhaps by intranasal administration of probiotics, might provide an approach to intervention in rhinovirus-associated illness or other viral infections.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37225510845&p=1pl&v=1&x=cC_QQTJtCDR1qED9-8SGHg
10.3402/ejpt.v5.22250,Medicine_easy_257,"In addition, alters who hold anger or pain are much more likely to hurt themselves than anyone else.a

Joubert encourages newly diagnosed people to seek support from trauma- and DID-informed helpers.",The small number of participants meant that observed power was very low in many of the analyses.,"For some people, especially people who have not yet been diagnosed or started therapy, this is true,a Joubert says. In addition, alters who hold anger or pain are much more likely to hurt themselves than anyone else.a

Joubert encourages newly diagnosed people to seek support from trauma- and DID-informed helpers. ""We are inspired to do the work we do by the people in the DID community and our own experiences.","However, a sample size of 11 does limit the number of inferential statistical tests that can meaningfully be performed. The small number of participants meant that observed power was very low in many of the analyses. In the future, dividing the concepts of interest into several smaller, more focused studies should alleviate some of these problems.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1038/s41467-018-05229-x,Medicine_easy_259,"The short-lived Wannier-Stark localization correlates with drastic changes to the electronic structure of the crystal and results, for example, in extremely high optical nonlinearity.","Under our biasing conditions, we can clearly see this effect also for the bulk semiconductor GaAs under study (see Supplementary Fig.","""If the electric field inside the crystal is strong enough, the electronic states can be localized to a few atoms. The short-lived Wannier-Stark localization correlates with drastic changes to the electronic structure of the crystal and results, for example, in extremely high optical nonlinearity. The first-ever experimental realization of Wannier-Stark localization in a gallium arsenide crystal was made possible through highly intense Terahertz radiation with field intensities of more than ten million volts per centimetre.","We also want to address the negligible role of high-harmonics generation for the interpretation of our data. Under our biasing conditions, we can clearly see this effect also for the bulk semiconductor GaAs under study (see Supplementary Fig. Nevertheless, we want to underline that this emission originates from the mid-infrared bias alone and it does not necessitate the presence of even a weak interband probe pulse.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1073/pnas.1411728112,Medicine_easy_260,"In a sense, the traditional second law only holds on average.","Since our second laws concern general state transformations, they can be applied to the case of deterministic work extraction or to the case of extracting a fluctuating amount of work, but here we apply our second laws to the former case.","""Even while individual parts of a system may become more ordered, the overall entropy of the total system (a measure of disorder) increases."" In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","Given the monotonicity of F α (ρ, ρ β ) we may easily compute the maximum amount of deterministic work which can be extracted when going from a system in state ρ to one in state ρ . Since our second laws concern general state transformations, they can be applied to the case of deterministic work extraction or to the case of extracting a fluctuating amount of work, but here we apply our second laws to the former case. From them, we know that a transition is possible if and only if",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1038/s41591-018-0091-x,Medicine_easy_261,"Therefore if a tumour becomes more aggressive, and spreads around the body, we would advise always taking a second biopsy.",Our analyses support the hypothesis that genes associated with clonal enhancers have higher bulk RNA levels ( Supplementary Fig.,"He continued: ""However our results suggest tumours switch different genes on and off as they progress, and can fundamentally change their 'appearance'. Therefore if a tumour becomes more aggressive, and spreads around the body, we would advise always taking a second biopsy. The cancer might have changed significantly in this time, and would respond to different treatments.","As the average expression is a function of the number of cells engaged in active transcription and the number of RNA molecule within each cell 33 , assuming a stochastic single-cell contribution, bulk mRNA levels should positively correlate with the number of transcribing cells. Our analyses support the hypothesis that genes associated with clonal enhancers have higher bulk RNA levels ( Supplementary Fig. 7a ).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34627030168&p=1pl&v=1&x=hF9k2ZTU-XUiToM72b9JHA
10.1073/pnas.1411728112,Medicine_easy_262,"That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly.""","However, this is only so when we do not allow ancillary systems that are then returned in the same state.","For instance, a small system can spontaneously become more ordered when it interacts with another system which barely seems to change. That means some rooms in the quantum house may spontaneously become much tidier, while others only become messier but only imperceptibly."" The results of the study give an improved understanding of how heat and energy is transformed on very small scales.","As we mentioned, in this toy thermodynamics, the law that governs state-to-state transitions is majorization. However, this is only so when we do not allow ancillary systems that are then returned in the same state. It is interesting to analyse how the laws change if we allow catalytic transitions between states.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.neuron.2014.04.039,Medicine_easy_264,Pinning down those details could pave the path to new drugs to stave off the defects in learning ability and memory that characterize Alzheimer's.,"(C) LTP of the fEPSP resulting from a strong inducing stimulus (Y, tetanus; three 1 s duration 100 Hz trains of stimuli delivered 15 s apart) is not significantly reduced by Ab1-42 (B, n = 7; 129% ± 6%) compared to vehicle (C; n = 7; 146% ± 13%; p = 0.375, n.s.","Pinning down those details could pave the path to new drugs to stave off the defects in learning ability and memory that characterize Alzheimer's. advertisement

A surprise finding by Madison's group suggests that in small, physiologically normal concentrations, A-beta tamps down a signal-boosting process that under certain conditions increases the odds that pyramidal nerve cells will transmit information they've received to other nerve cells down the line. When incoming signals to the pyramidal tract build to high intensity, pyramidal cells adapt by becoming more inclined to fire than they normally are.","(B) LTP of the fEPSP, following a weak inducing stimulus ([, five bursts of four stimuli at 100 Hz, 400 ms interburst interval) is reduced by Ab1-42 (B, n = 7; 105% ± 5%) compared to vehicle (C; n = 7; 115% ± 4%) (p < 0.01 at 35-40 min posttetanus). (C) LTP of the fEPSP resulting from a strong inducing stimulus (Y, tetanus; three 1 s duration 100 Hz trains of stimuli delivered 15 s apart) is not significantly reduced by Ab1-42 (B, n = 7; 129% ± 6%) compared to vehicle (C; n = 7; 146% ± 13%; p = 0.375, n.s. not significant).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140618131955.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.immuni.2019.05.007,Medicine_easy_266,Note: material may have been edited for length and content.,The VP1 protein among these strains shows only $50% amino acid identity .,"Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Note: material may have been edited for length and content. For further information, please contact the cited source.","The 10 serum antibodies could be categorized into three classes. The VP1 protein among these strains shows only $50% amino acid identity . The second class consisted of antibodies B403, C601, and C602, which had strong blockade activity towards the vaccine strain and the earlier pandemic GII.4 1997 strain but not to GII.4 strains that emerged post vaccination.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39496179252&p=1pl&v=1&x=1Ybn3Q7h2gozRyncgH43aA
10.1016/j.cell.2015.07.058,Medicine_easy_269,"""Our work implies that we may be able to engineer viruses that selectively kill cancer cells.""","The MDC1 scaffolding protein binds gH2AX and recruits additional MRN, ATM, DDR kinases, and effectors into nuclear foci readily visualized by light microscopy .","O'Shea says this may explain why people with conditions resulting in high levels of cellular DNA damage (e.g., cancer, chemotherapy, inflammation and aging) are more susceptible to viral infections. ""Our work implies that we may be able to engineer viruses that selectively kill cancer cells."" In cancer cells, MRN is already so preoccupied with responding to DNA breaks in cancer cells that an engineered virus could sneak in undetected.","In Brief gH2AX foci discriminate ''self'' and ''nonself'' genomes and determine whether a localized anti-viral or global ATM response is appropriate, providing an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability. The MDC1 scaffolding protein binds gH2AX and recruits additional MRN, ATM, DDR kinases, and effectors into nuclear foci readily visualized by light microscopy . gH2AX DDR foci play an important role in nucleating ATM and effector kinases to induce the global phosphorylation of DDR substrates, including KAP1, RPA32, 53BP1, and p53, that elicit cell-cycle arrest, repair, senescence, or apoptosis .",[1],Medicine,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.2337/db11-1488,Medicine_easy_270,"Sure enough, having higher levels of IGFBP-2 was associated with a variety of factors, such as a lower BMI, smaller waist circumference, smaller fatty liver index, and a lower risk of type 2 diabetes.","First, unlike both Sandhu et al.","Their findings suggested that the gene for IGFBP-2 in the liver was edited early in life, setting the mice up for type 2 diabetes later. Sure enough, having higher levels of IGFBP-2 was associated with a variety of factors, such as a lower BMI, smaller waist circumference, smaller fatty liver index, and a lower risk of type 2 diabetes. But for the subjects with type 2 diabetes the same chemical padlock found in the diabetic mice was also more likely to appear, again suggesting that for many people, diabetes could be influenced, if not caused, by epigenetic changes early in life.","Despite several areas of concordance between our study and prior epidemiologic and laboratory data, there are limitations to the current investigation that must be considered in its interpretation. First, unlike both Sandhu et al. (15, , we did not observe a relation of diabetes with total IGF-I, only a relation of diabetes with free IGF-I.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37654789048&p=1pl&v=1&x=Fe02NGVhEEhdNaHtErvtQg
10.1001/jamasurg.2018.0672,Medicine_easy_273,"Also, patients with inadequate functional health literacy had a lower health-related quality of life in terms of physical function, bodily pain, vitality, social functioning, mental health and physical aspects.","There were no statistical differences between the 3 groups in age, sex, type of anesthesia and surgery, or ASA classification ( Table 1) .","The poor recovery score among participants with inadequate literacy was 37.2 and 22.9 for problematic.The group with sufficient literacy had a score of 17.7. Also, patients with inadequate functional health literacy had a lower health-related quality of life in terms of physical function, bodily pain, vitality, social functioning, mental health and physical aspects. The researchers note that they did not have data on education or socioeconomic status, nor were they aware of how many can speak and read Swedish, which would also pose a challenge to understanding healthcare information, and will require further research.","Most (n = 427 [60.6%]) of the 704 patients undergoing day surgery reported sufficient FHL, 223 (31.7%) reported problematic FHL, and 54 (7.7%) reported inadequate FHL. There were no statistical differences between the 3 groups in age, sex, type of anesthesia and surgery, or ASA classification ( Table 1) . The global score of SwQoR indicated poor recovery in both inadequate (37.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33897057585&p=1pl&v=1&x=gsIoyrhoCs5f3L7Wv3ex4w
10.1038/s41598-018-29793-w,Medicine_easy_274,"Researchers found that the bacteria found inside study participantsa nasal microbiome types were linked to how much cold virus was found inside the body, and how cold symptoms manifested person to person.",The scores were lower in Cor/All cluster compared to Staph (P = 0.007) and Ps/Mix clusters (P = 0.013) (Fig.,"These nasal microbiome types are linked to how bad your cold symptoms get, and how well you fight the virus off in the first place. Researchers found that the bacteria found inside study participantsa nasal microbiome types were linked to how much cold virus was found inside the body, and how cold symptoms manifested person to person. Itas further noted in the press release that genes might play a role in both the composition of your nasal microbiome, and how bad your cold symptoms get.","With total Cold Symptom scores (runny nose, plugged nose, sneezing, sore throat, scratchy throat, cough, hoarseness, head congestion, and feeling tired) a significant D0 cluster effect was found (P = 0.011). The scores were lower in Cor/All cluster compared to Staph (P = 0.007) and Ps/Mix clusters (P = 0.013) (Fig. When individual symptoms were analyzed, the D0 cluster effect was found not significant (P > 0.1) in all analysis models.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37227743738&p=1pl&v=1&x=2zyW9bON3VHP6zbXr8qTXQ
10.1001/jamaoncol.2018.3701,Medicine_easy_275,"""These data further demonstrate the importance of adjunctive biomarkers regarding PSA assessment, especially regarding the decision to either avoid or to proceed to prostate biopsy,"" said principal investigator Neal Shore , M.D., Medical Director at the Carolina Urologic Research Center , Atlantic Urology Clinics in Myrtle Beach, South Carolina.","Furthermore, our study and the microcosting methodology revealed additional insights that warrant further discussion.","NEWS RELEASE REGULATED INFORMATION

Real-world study shows that SelectMDx helps urologists more confidently determine

the need for an initial prostate biopsy

IRVINE, CA, and HERSTAL, BELGIUM - 07.00 CEST, 7 November 2018 - MDxHealth SA (Euronext: MDXH.BR) or the ""Company"" today announces that the journal Urology Practice has published a study demonstrating the clinical utility of SelectMDx, the Company's non-invasive 'liquid biopsy' test to identify patients at increased risk of aggressive prostate cancer, in guiding initial prostate biopsy decision-making. ""These data further demonstrate the importance of adjunctive biomarkers regarding PSA assessment, especially regarding the decision to either avoid or to proceed to prostate biopsy,"" said principal investigator Neal Shore , M.D., Medical Director at the Carolina Urologic Research Center , Atlantic Urology Clinics in Myrtle Beach, South Carolina. ""The SelectMDx biomarker offers physicians and patients an easily obtained urine-based test, which combines cost effectiveness with clinical utility, improving urologists' ability to diagnose and treat prostate cancer.""","Overall, our findings were consistent with this prior study. Furthermore, our study and the microcosting methodology revealed additional insights that warrant further discussion. First, with the continued controversy regarding prostate cancer screening, the present study provides insight on an important but understudied piece of this debate-cost.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37616037423&p=1pl&v=1&x=gXp7O7pmGkPY1w04wbVK7A
10.1088/1741-2552/aabc9b,Medicine_easy_276,"""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal.""","The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded.","The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods. ""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal."" An adaptive system like the one being tested here could offer an effective alternative and may also limit adverse effects of traditional deep brain stimulation, but considerable testing remains to be done.","While the total energy delivered by adaptive stimulation was substantially less than that of open-loop stimulation, blinded clinical ratings confirmed similar efficacy for both approaches. The classifier algorithm performed as expected, appropriately detecting changes in gamma band power and triggering reduction in DBS amplitude when the gamma threshold was exceeded. Although this approach has shown promise 1,2 , the STN LFP is a low amplitude signal that is strongly affected by stimulation artifact when stimulation is delivered on adjacent contacts.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34178086266&p=1pl&v=1&x=nNMoIIdQdsrnpbYA5pi8RQ
10.1093/eurpub/cky178,Medicine_easy_277,"spoke mainly of an increasingly strapped and fragmented National Health Service, the country's public health system.","After controlling for regional fixed effects, to address time-consistent variations in surveillance and health infrastructure, the corresponding figure increased to 0.53 percentage points (95% CI: 0.37-0.69 percentage points).","They also mentioned the fact that there is no system in place to remind people to get their shots, among other barriers to access. spoke mainly of an increasingly strapped and fragmented National Health Service, the country's public health system. They also mentioned the fact that there is no system in place to remind people to get their shots, among other barriers to access.","Our unadjusted model estimates that each 1% increase in real public health expenditure was associated with a significant increase in MMR coverage of 0.29 percentage points (95% CI: 0.19-0.40 percentage points). After controlling for regional fixed effects, to address time-consistent variations in surveillance and health infrastructure, the corresponding figure increased to 0.53 percentage points (95% CI: 0.37-0.69 percentage points). Similarly, when correcting for regional time trends, every 1% increase in real public health expenditure per-capita (corresponding to an average of E17 percapita) was associated with an increase of 0.50 percentage points in MMR coverage (95% CI: 0.36-0.65 percentage points).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37159214862&p=1pl&v=1&x=CcPjjUifeL13VJ3H086Sjg
10.1073/pnas.1411728112,Medicine_easy_278,"Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work.","Now, let us note that","In a sense, the traditional second law only holds on average. Surprisingly, the researchers found that not only does the second law hold at such small scales, but there are actually many other second laws at work. In other words, just like larger systems, small systems also tend to become more disordered.","we know that for n sufficiently large Now, let us note that (G38), and the fact that the dimension of the catalyst is N = n2 n−1 .",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1016/j.jpain.2017.11.005,Medicine_easy_279,How (in the hell) could it do that?,was determined to have a sham acupuncture arm with a high likelihood of bias from unblinding.,"Long story short, the jury's still out. How (in the hell) could it do that? It found no significant uptick in successful births among those who underwent acupuncture versus those who didn't.","13, 26, 41, 49, 59, 103 In one trial, two types of sham acupuncture were used, although only one type (non-needle sham acupuncture) was found to have an intermediate likelihood of bias from unblinding. was determined to have a sham acupuncture arm with a high likelihood of bias from unblinding. None of the 10 new trials included in this analysis had dropout rates of higher than 25%.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38497695155&p=1pl&v=1&x=s_16A13LceP0QMt7V7o-QA
10.1111/gcb.13276,Medicine_easy_280,"""We want this index to be used to predict how corals might react to future bleaching events.",The effect of extrinsic factors P ext was found by correlation between BRI j and taxon-sBRI j (Eqn 17).,"""Using very large data sets, we have teased out valuable information that will help researchers identify global trends and learn about individual corals,"" says coauthor Vadim Backman, professor of biomedical engineering. ""We want this index to be used to predict how corals might react to future bleaching events. The index will be available online, so that data on corals can be added as they become available, making the tool even more robust.","The threshold at which uncertainty of a report increases total uncertainty can be determined; reports with average-dB jk more than twice the average of all reports for a taxon increase total uncertainty and are candidates for exclusion (if minimizing the uncertainty is the goal, Eqns 30-33, Text S1.6). The effect of extrinsic factors P ext was found by correlation between BRI j and taxon-sBRI j (Eqn 17). Because we cannot eliminate effects of intrinsic factors on taxon-sBRI j (e.g., a site may contain mostly bleaching-susceptible coral taxa), P ext is the upper bound of the true variance due to extrinsic factors, and it is expected to increase in accuracy for sites with diverse bleaching responses (i.e., in the limit of a high number of taxa per site n, Eqns 17-19).",[1],Medicine,train,1.0,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1073/pnas.1613193114,Medicine_easy_281,"Under the stabilization scenario, demand on an average day would climb 3 percent, and on a peak day, 7 percent.","As such, even absent population and income changes, climate change will demand significant changes to the electric grid.","Under both scenarios, if the nation were to experience temperatures like the ones predicted 100 years from now with today's infrastructure, the grid would be overtaxed. Under the stabilization scenario, demand on an average day would climb 3 percent, and on a peak day, 7 percent. Absorbing this would require an investment of $70 billion.","Overall, if the US had faced, over the past decade, the warmer climate that scientists predict for the future, our results show that much greater generation or storage capacity would have been needed. As such, even absent population and income changes, climate change will demand significant changes to the electric grid. ERCOT covers Texas only and can be thought of as more representative of warmer regions.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/electricity-costs-a-new-way-theyll-surge-in-a-warming-world/
10.1126/sciadv.aau1291,Medicine_easy_283,"This way of delivering drugs also has the advantage of not increasing the local pressure where the drug exits the device because the drug molecules are not in a solvent - they exit the device ""dry"".","Figure 3 overviews the frequency of pathological events for the control experiments with 4AP injection but no GABA delivery (n = 8), the case of GABA delivery after 4AP injection (n = 3), and the case of GABA delivery before 4AP injection (n = 4) (see table S1 for the complete data set).","We show that the implant can treat problems in the brain, such as epileptic seizures, by delivering brain chemicals - known as neurotransmitters - directly to the cells in the brain that cause the problem. This way of delivering drugs also has the advantage of not increasing the local pressure where the drug exits the device because the drug molecules are not in a solvent - they exit the device ""dry"". This stopped the seizures.","Neither interictal spikes nor seizures were observed when the GABA delivery was initiated before the 4AP injection. Figure 3 overviews the frequency of pathological events for the control experiments with 4AP injection but no GABA delivery (n = 8), the case of GABA delivery after 4AP injection (n = 3), and the case of GABA delivery before 4AP injection (n = 4) (see table S1 for the complete data set). The decrease in pathological activity was found to be significant (P < 0.05) in the case of delivering GABA before 4AP relative to the control experiments.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34961518391&p=1pl&v=1&x=gYock5HcirAl4GI18svsfA
10.1038/s41467-018-04627-5,Medicine_easy_285,Subjects in the control group showed no changes in diffusion rates or structure between MRI measurements.,"Similarly, in the ILF, we saw a significant main effect of Table 3 , the group-by-time interaction approached significance for the quadratic term for FA in the left AF and ILF, but not for MD in the AF or ILF, or for either parameter in the CC.","That plasticity points to changes brought about by the environment, indicating that these regions are not inherently inflexible structures. Subjects in the control group showed no changes in diffusion rates or structure between MRI measurements. But for subjects who took part in the tutoring program, reading skills improved by an average of one full grade level.","In the left AF, we found a significant main effect of group (F(1,125) = 7.047, p = 0.009) but not of time (F(1,125) = 1.033, p = 0.31) and a significant groupby-time interaction (F(1,125) = 4.97, p = 0.028), consistent with a decrease in MD over time that was specific to the intervention subjects. Similarly, in the ILF, we saw a significant main effect of Table 3 , the group-by-time interaction approached significance for the quadratic term for FA in the left AF and ILF, but not for MD in the AF or ILF, or for either parameter in the CC. Sessions were systematically spaced over time, and this timing was consistent across subjects; hence ""session"" was highly correlated with ""days"" (r(127) = 0.97, p < 0.001).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1126/science.1256773,Medicine_easy_286,"""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane.",Microtubules grew outward radially within each aster.,"""We believe our work is a step forward, not only for understanding the assembly of the cleavage furrow but also, more generally, for understanding the biophysics of cytokinesis signaling."" ""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane. The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract.","The morphology of the midplane in zygotes, as defined by microtubule morphology and CPC/centralspindlin localization, was strikingly similar to that of the AAIZ in extracts (Fig. Microtubules grew outward radially within each aster. At the AAIZ, EB1 comets from both directions entered antiparallel bundles, where they usually disappeared (Fig.",[1],Medicine,train,1.0,news,http://www.science20.com/news_articles/cytokinesis_lite_cellular_division_now_with_no_cells-148202
10.1001/jama.2013.277165,Medicine_easy_287,"The study is being released early online to coincide with its presentation at the European Society of Cardiology Congress 2013

""Major progress has been made in the management of non-ST-segment elevation [a certain pattern on an electrocardiogram] acute coronary syndromes (NSTE-ACS) because of the availability of potent combinations of oral antiplatelet agents, injectable anticoagulants, and increasing use of an invasive strategy.",A lower dose of otamixaban did not achieve better results.,"The study is being released early online to coincide with its presentation at the European Society of Cardiology Congress 2013

""Major progress has been made in the management of non-ST-segment elevation [a certain pattern on an electrocardiogram] acute coronary syndromes (NSTE-ACS) because of the availability of potent combinations of oral antiplatelet agents, injectable anticoagulants, and increasing use of an invasive strategy. The primary outcome of death or new myocardial infarction through day 7 occurred in 5.5 percent of the patients treated with otamixaban vs. 5.7 percent of the patients treated with UFH plus eptifibatide. Otamixaban did not significantly reduce the risk of any of the components of the primary outcomes, either death or heart attack, or of any of the secondary efficacy outcomes, including procedural thrombotic complications.","These results were consistent across patient subgroups. A lower dose of otamixaban did not achieve better results. 12 In a post hoc analysis, a 44% to 48% RR reduction in death or myocardial infarction was seen in the midrange doses compared with UFH plus eptifibatide, similar to those tested in the TAO trial.",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/anticoagulant-does-not-reduce-rate-of-ischemic-events-among-certain-patients-undergoing-pci
10.1111/cdev.12250,Medicine_easy_288,"Of course, the vanity of focusing on social hierarchies never fares too well in the end.","This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed.","Allen says he believes that part of the problem may be that as popular youth grow older, they have to do increasingly extreme things in order to grab the attention of their peers and keep it. Of course, the vanity of focusing on social hierarchies never fares too well in the end. ""The quiet, not-so-cool kids do well in the long term,"" Allen says.","Although no measures of pubertal status were available in this study, by the ages of 13-15, the period during which pseudomature behavior was observed, the vast majority of teens are well into puberty. This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed. Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular"").",[1],Medicine,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1210/en.2015-2036,Medicine_easy_289,The use of sunscreen can also affect vitamin D synthesis.,"Interestingly, basal levels of ID1 protein expression were significantly increased in the VDR KD cell line relative to control cells ( Figure 3D ) and the VDR Rescue cell line had lower levels of ID1 ( Figure 3E ; reprobed Western blot from Figure 1D ).","Those who don't get enough sun exposure, or people with darker skin, are more likely than fair-skinned individuals who spend time outdoors each day to be deficient. The use of sunscreen can also affect vitamin D synthesis. Mice fed a diet deficient in vitamin D developed palpable tumors an average of seven days sooner than their peers, and after six weeks of growth those tumors were significantly larger in size than those in animals with adequate vitamin D levels.","This suppression of Id1 by calcitriol treatment was substantially abrogated in the VDR KD cells ( Figure 3D ). Interestingly, basal levels of ID1 protein expression were significantly increased in the VDR KD cell line relative to control cells ( Figure 3D ) and the VDR Rescue cell line had lower levels of ID1 ( Figure 3E ; reprobed Western blot from Figure 1D ). These results suggest that VDR might directly regulate Id1 in BCa cells and that basal endogenous levels of VDR suppress Id1 expression.",[1],Medicine,train,1.0,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1016/j.jpeds.2017.10.028,Medicine_easy_291,"But if you can connect with a kid when they're doing something right, they're more likely to do that again in the future.""","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498).","It's not just a Texas thing; it's proven not to work. But if you can connect with a kid when they're doing something right, they're more likely to do that again in the future."" As a father himself, he knows this is difficult to adhere to, but he believes this can happen even in the most difficult situation.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1007/s00213-014-3810-0,Medicine_easy_292,"/ no comments

These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues

Your gut feeling could be causing your anxiety.",a Attentional vigilance did not differ between groups during masked trials of the attentional dot-probe task.,"/ no comments

These Bacteria Could Be The Leading Cause Of Your Anxiety -- And Other Issues

Your gut feeling could be causing your anxiety. There is a connection between anxiety and an upset gut. In the study, when the bacteria's healthy functions were restored, mood and behavior leveled out, reducing or eliminating anxious feelings.","*p<0.05 Fig. a Attentional vigilance did not differ between groups during masked trials of the attentional dot-probe task. b Participants showed decreased attentional vigilance to negative versus positive words in the unmasked condition of the dot-probe task after B-GOS but not FOS intake compared to placebo involuntary deployment of attention ), whereas at longer stimulus durations, it may further involve a difficulty to disengage from salient emotional stimuli .",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/can-bacteria-cause-anxiety/
10.1038/ncomms14514,Medicine_easy_293,"It turns out with these clusters, every single cluster is exactly the same structure.","The LSPR peak energy of the clusters saturates to a value of 1.06 eV on prolonged oxidation, only marginally higher than the saturation peak energy of 0.99 eV for the 6 nm Cu 2 Se NCs and the value of 1 eV from Manna and coworkers .","This crystal structure is a result of internal strain in the clusters. It turns out with these clusters, every single cluster is exactly the same structure. Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","In this regard the clusters show behaviour similar to that of the larger 6 nm NCs, even though the oxidation kinetics appear to be slower for the 2 nm clusters (Fig. The LSPR peak energy of the clusters saturates to a value of 1.06 eV on prolonged oxidation, only marginally higher than the saturation peak energy of 0.99 eV for the 6 nm Cu 2 Se NCs and the value of 1 eV from Manna and coworkers . The difference is only 7% and could be due to increased carrier confinement in the clusters, known to cause a blue-shift or due to differences in the local medium refractive index presented by the ligand shell.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uNVFlIGRBVk/
10.1038/s41467-018-04408-0,Medicine_easy_294,Recognition of the link between testosterone and BAFF is completely new.,"Since BAFF production in secondary lymphoid organs relies heavily on the FRC stromal compartment 47 , these events provide a mechanism for the increased splenic production of BAFF in testosterone/AR deficiency.","If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent. Recognition of the link between testosterone and BAFF is completely new. Ultimately, the researchers hope that their findings lead to more effective medications for lupus and other autoimmune diseases that impact so many women.","Thus, the decreased splenic noradrenaline levels in testosterone/AR deficiency increases the number of FRCs. Since BAFF production in secondary lymphoid organs relies heavily on the FRC stromal compartment 47 , these events provide a mechanism for the increased splenic production of BAFF in testosterone/AR deficiency. The increase in B cell number in the lymph nodes was less pronounced than in the spleen, and not associated with increased FRC number, suggesting that this is a systemic effect of BAFF.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34230456675&p=1pl&v=1&x=lt6z2jq1xfFKoXvXclXMKg
10.1038/s41467-018-05229-x,Medicine_easy_295,The system remains stable as long as the rubber band is as strong as the repulsion is.,"When an electric field of the order of E WSL is applied, localization of wave functions occurs only in one lattice direction, while the electronic bonding structure perpendicular to the field remains intact.","Using the ultrafast laser systems at the University of Konstanz, Wannier-Stark localization has now been demonstrated for the first time. The system remains stable as long as the rubber band is as strong as the repulsion is. If this is the case, the beads neither move closer to each other, nor do they move away from each other -- the distance between them remains about the same.","2b , c. The step-like character and field-independent position of the central feature in Wannier-Stark electro-absorption is explained microscopically in Fig. When an electric field of the order of E WSL is applied, localization of wave functions occurs only in one lattice direction, while the electronic bonding structure perpendicular to the field remains intact. A step-function-like absorption spectrum characteristic for twodimensional electron systems arises with an onset of absorption at a higher energy E gap 2D , which may be related to the atomic transition energies in the compound (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1002/cncr.30912,Medicine_easy_296,"Next Steps

The researchers have found that early consideration of palliative care in a treatment plan for patients with solid tumors improves patients' understanding of the prognosis.","First, we performed the study at a single, tertiary care site in a patient sample with limited socioeconomic diversity, which may limit the generalizability of findings to other, more diverse populations or to patients in other geographic areas.","The researchers attribute this to higher levels of distress seen in people with AML due to the urgency of their treatment decisions. Next Steps

The researchers have found that early consideration of palliative care in a treatment plan for patients with solid tumors improves patients' understanding of the prognosis. They hope to implement a similar study in patients with leukemia.","Several limitations of this study warrant discussion. First, we performed the study at a single, tertiary care site in a patient sample with limited socioeconomic diversity, which may limit the generalizability of findings to other, more diverse populations or to patients in other geographic areas. Second, it is possible that differences in illness severity and other factors could confound the relation between symptom burden and health care utilization.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/people-with-leukemia-and-their-oncologists-have-vastly-different-perceptions-of-prognosis/
10.1016/j.cell.2013.08.004,Medicine_easy_297,"If you think about, it makes sense to have a buffering mechanism in place to provide some stability to the clock.",Of particular interest were two kinases that caused period lengthening.,"When they blocked the activity of SIK1, the mice adjusted faster to changes in light cycle. If you think about, it makes sense to have a buffering mechanism in place to provide some stability to the clock. The clock needs to be sure that it is getting a reliable signal, and if the signal occurs at the same time over several days it probably has biological relevance.","Silencing of several of the genes caused significant changes in period length, which would indicate a role in regulating phase delays of the clock . Of particular interest were two kinases that caused period lengthening. It is closely related to CsnkE, which is mutated in the Tau mutant hamster, which also shows period lengthening .",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/08/130829124013.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.jpain.2017.11.005,Medicine_easy_298,"""I think its mechanisms depend on the disease it's trying to treat,"" he says.","An additional 13 trials were identified, with data received for a total of 20,827 patients from 39 trials.","Napadow's take: It's not a panacea that will cure all ills, but there are some areas where acupuncture is promising and, given its safety profile, should be recommended. ""I think its mechanisms depend on the disease it's trying to treat,"" he says. ""This is the area where we have the most data,"" Napadow says.","-Acupuncture has a clinically relevant effect on chronic pain that persists over time -The effect of acupuncture cannot be explained only by placebo effects -Factors in addition to the specific effects of needling are important contributors -Referral for acupuncture treatment is a reasonable option for chronic pain patients An additional 13 trials were identified, with data received for a total of 20,827 patients from 39 trials. Acupuncture was superior to both sham and no acupuncture control for each pain condition (all p<0.001) with differences between groups close to 0.5 standard deviations (SD) for comparison with no acupuncture control and close to 0.2 SDs in comparison with sham.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38497695155&p=1pl&v=1&x=s_16A13LceP0QMt7V7o-QA
10.1016/j.cell.2015.07.058,Medicine_easy_299,This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability.,ATM activation triggers ATM autophosphorylation at Ser1981 .,"MRN starts a domino effect, activating histones on surrounding chromosomes, which summons a cascade of additional proteins, resulting in a cell-wide, all-hands-on-deck alarm to help mend the DNA. This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability. Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea.","HU and KU-55933 also prevent the phosphorylation of DNA-PKcs ( Figure 3B ), indicating that DNA-PK is activated downstream of ATM in response to virus DNA replication. ATM activation triggers ATM autophosphorylation at Ser1981 . Etoposide induces cellular DNA breaks and the phosphorylation of ATM at discrete DDR foci ( Figure 3C ).",[1],Medicine,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1534/genetics.116.197285,Medicine_easy_300,They show nature still has the edge over scientists hoping to solve human problems with GM organisms.,"Driver alleles, by contrast, carry a substantial cost that is codominant, s d0 = 0.1 = s dd /2.","""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said. They show nature still has the edge over scientists hoping to solve human problems with GM organisms. ""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said.","This will allow us to dissect the particular role each individual parameter plays in the general behavior of the model, and the evolution of resistance specifically. Driver alleles, by contrast, carry a substantial cost that is codominant, s d0 = 0.1 = s dd /2. In those analyses where both the driver and the resistance allele carry a cost, we assume that these costs are codominant to each other,",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1073/pnas.1403984111,Medicine_easy_301,"The sheer number of animals being killed shows us that, up until the UAVs take to the air, most poachers have been able to operate with impunity.",Illegal killing was most pervasive in the populations of Central Africa (Figs.,"This is critical since poachers will try to change their behavior once they learn that they are at an extremely high risk of apprehension. The sheer number of animals being killed shows us that, up until the UAVs take to the air, most poachers have been able to operate with impunity. The most important finding is that in every area where we have put our solutions package to work and the UAVs are flying, poaching stops with 5 to 7 days.","The three regions of Africa (Central, East, and Southern) demonstrated different trends that were captured by both approaches. Illegal killing was most pervasive in the populations of Central Africa (Figs. 2 and 3) , where results supported probable annual declines each year since at least 2007 ( Fig.",[1],Medicine,train,1.0,news,http://www.theecologist.org/News/news_analysis/2731159/satellites_mathematics_and_drones_take_down_africas_poachers.html
10.1016/j.neuron.2018.12.026,Medicine_easy_304,"""But actually, our results suggest that loss of inhibition might represent a useful compensation that the brain is doing, or might be unrelated to disease symptoms.",Mutant and WT PYR cells did not differ in baseline recording or stimulation parameters or in EPSC or IPSC kinetics including latency and EPSC-IPSC delay (Table S2 ; Figure S1 ).,"Instead, this altered balance seems to be a compensatory mechanism that stabilizes brain activity in response to the disorder. ""But actually, our results suggest that loss of inhibition might represent a useful compensation that the brain is doing, or might be unrelated to disease symptoms. And if you go in there and increase inhibition, you might make things worse or you might not affect things at all.""","Overall, in Fmr1 À/y , Cntnap2 À/À , 16p11.2 del/+ and Tsc2 +/À mice, the area under the mean inputoutput curve for EPSCs was 0.57, 0.36, 0.86, and 0.92 of WT, respectively; for IPSCs it was 0.55, 0.18, 0.63, and 0.74 of WT; and for E-I ratio was 2.24, 1.79, 1.29, and 1.37 of WT. Mutant and WT PYR cells did not differ in baseline recording or stimulation parameters or in EPSC or IPSC kinetics including latency and EPSC-IPSC delay (Table S2 ; Figure S1 ). Thus, these 4 genetically distinct ASD mutants exhibited a common impairment in feedforward IPSCs, variably coupled to a loss of feedforward EPSCs, yielding a common increase in E-I conductance ratio.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1373/clinchem.2012.187617,Medicine_easy_305,"While a flight to Mars will expose astronauts to more radiation and longer durations of space flight, the researchers said this study is one indication that the flight itself isn't likely to permanently harm human bodies.","contribute to increased gut permeability, this change in the gut microbiome may result in a leaky gut and yield increased concentrations of endotoxins such as LPS in the circulation.","Overall, NASA views this study as good news so far for their plans of crewed missions to Mars. While a flight to Mars will expose astronauts to more radiation and longer durations of space flight, the researchers said this study is one indication that the flight itself isn't likely to permanently harm human bodies. What the researchers did

Conducting a fecal study in space is harder than you think.","In addition to improved insulin activity and glucose tolerance, because lower levels of Bifidobacterium spp. contribute to increased gut permeability, this change in the gut microbiome may result in a leaky gut and yield increased concentrations of endotoxins such as LPS in the circulation. The immune system recognizes LPS as a microbial pattern triggering TLR signaling and causing inflammation.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1038/s41598-018-25573-8,Medicine_easy_306,"The team had similar results when they used ovarian tumour samples taken directly from patients, showing that their chicken egg model provides a convenient system for replicating human cancer.","We further demonstrated that doxorubicin is preferentially delivered to the tumor when the nanoparticle formulation was used, as shown by the preferential appearance of red fluorescence of doxorubicin in the tumor.","The team had similar results when they used ovarian tumour samples taken directly from patients, showing that their chicken egg model provides a convenient system for replicating human cancer. This conclusion is supported by their detailed characterization of the tumour, demonstrating that it possesses all major cancer features. ""We were surprised when the tumour was formed in three days,"" says Tamanoi. ""","Nanoparticle formulation enables higher amount of doxorubicin to be used. We further demonstrated that doxorubicin is preferentially delivered to the tumor when the nanoparticle formulation was used, as shown by the preferential appearance of red fluorescence of doxorubicin in the tumor. This is in contrast with the distribution of red fluorescence when free doxorubicin was injected.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34220579892&p=1pl&v=1&x=hyv7yBfI9spqaAdmPr3ViA
10.3402/ejpt.v5.22250,Medicine_easy_308,"People seem to forget this sometimes.a

Despite the profound challenges that both trauma and DID have given Joubert, she also says that her systemas adaptation to trauma has been nothing short of lifesaving.",The IM may be useful in treatment settings to assess progress or change over time.,"If a therapist makes you uncomfortable or raises red flags for you, you don't have to see them. People seem to forget this sometimes.a

Despite the profound challenges that both trauma and DID have given Joubert, she also says that her systemas adaptation to trauma has been nothing short of lifesaving. aDID saved our life.","Directions for future research are also discussed, including expanding the IM from this pilot. The IM may be useful in treatment settings to assess progress or change over time. They also propose that fragmentation of information storage may occur only when that information is personally relevant, or when attempting to transfer information between different types of identities that serve different roles.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1038/s41598-018-30656-7,Medicine_easy_309,"Thatas because this skill likely co-evolved with planning abilities, complex cognition, and the ability to use language.","These differences suggest that sharing the burden of information gathering and decision-making across multiple individuals has benefits that are not always immediately obvious: colonies rely on adaptive satisficing without suffering major increases in the probability of errors, while individuals face the full conflict between accuracy of choice and time to decision.","In other words, they may play out the potential steps in their brain before settling on a viable solution they can perform. Thatas because this skill likely co-evolved with planning abilities, complex cognition, and the ability to use language. While this latest study doesnat imply that the cognitive powers of a crow rival those of humans or apes, it hints that they too have evolved to perform complex tasks with coordination and ease.","Individuals are also vulnerable to decoy effects in choices among options that vary in multiple attributes 33 , while whole colonies are more resilient towards decoys, consistently adhering to economic principles of rational choice 40 . These differences suggest that sharing the burden of information gathering and decision-making across multiple individuals has benefits that are not always immediately obvious: colonies rely on adaptive satisficing without suffering major increases in the probability of errors, while individuals face the full conflict between accuracy of choice and time to decision. Given the obligatory eusocial condition of our subject species, the functional significance of decisions by isolated workers deserves some caveats.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1073/pnas.1414221111,Medicine_easy_310,"Whole genome sequencing of the Plasmodium falciparum, the deadliest of the malaria parasites, revealed that (+)-SJ733 disrupted activity of the ATP4 protein in the parasites.","The three rodent malaria species (P. berghei, Plasmodium vinckei, and Plasmodium chabaudi) were all significantly less sensitive to (+)-SJ733 than was P. falciparum both ex vivo (SI Appendix, Fig.","""These results indicate that SJ733 and other compounds that act in a similar fashion are highly attractive additions to the global malaria eradication campaign, which would mean so much for the world's children, who are central to the mission of St. Whole genome sequencing of the Plasmodium falciparum, the deadliest of the malaria parasites, revealed that (+)-SJ733 disrupted activity of the ATP4 protein in the parasites. Researchers showed that inhibiting ATP4 triggered a series of changes in malaria-infected red blood cells that marked them for destruction by the immune system.","Unconstrained docking of the structure of (+)-SJ733 to this homology model revealed one predicted binding site, which is enveloped by the cluster of residues bearing resistance-conferring mutations (Fig. The three rodent malaria species (P. berghei, Plasmodium vinckei, and Plasmodium chabaudi) were all significantly less sensitive to (+)-SJ733 than was P. falciparum both ex vivo (SI Appendix, Fig. S2E ), which is predicted to encode a loop within the (+)-SJ733 binding site (purple ribbon, Fig.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1002/ejhf.69,Medicine_easy_311,"""People seem to mix the concepts of prevention and treatment together,"" he said.",Integrating incident HF into cardiovascular disease risk prediction and prevention strategies should be considered.,"But don't think you are treating heart failure per se until the results of the dedicated heart failure trials come out."" ""People seem to mix the concepts of prevention and treatment together,"" he said. ""We have now very good evidence across all trials with SGLT-2 inhibitors for prevention of heart failure.","48 In conclusion, the present study underscores the importance of vascular disease in relation to risk of HF but also reaffirms the existence of an important yet largely ignored clinical entity of HF without preceding vascular disease. Integrating incident HF into cardiovascular disease risk prediction and prevention strategies should be considered. Targeted HF prevention strategies may be beneficial at the population level and need further study.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38228224591&p=1pl&v=1&x=VEvBLGqbB4NvvfbrYC9-sA
10.1126/science.aap7778,Medicine_easy_312,"In a fourth cave, the scientists also found another pile of evidence pointing to Neanderthals: painted shells, some with a single hole drilled through them, perhaps to accommodate a string.","The implication is, therefore, that the artists were Neandertals.","And clearly, some of the paintings required hearty determination. In a fourth cave, the scientists also found another pile of evidence pointing to Neanderthals: painted shells, some with a single hole drilled through them, perhaps to accommodate a string. ""I think we should accept them as part of us.","In this age range, Iberia was exclusively populated by Neandertals, as indicated by numerous diagnostic osteological remains, including articulated skeletons (28, 29) . The implication is, therefore, that the artists were Neandertals. This is a 1 cm 5 cm restricted and nonfigurative set of subjects and could represent the extension of Neandertal body art to the external world.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/GPBNewsFeed/~3/RRsCDiK7bt8/cave-art-may-have-been-handiwork-neanderthals
10.1080/10635150701775111,Medicine_easy_314,"""Perhaps such fluctuations are not given the attention this paper suggests they ought to give.""",They argue that two populations separated by a region outside the climatic niche envelope of the two populations makes current gene flow unlikely and thus supports both populations being considered separate species.,"Ilya Maclean, lecturer in natural environment at the University of Exeter, thinks this study can help people understand which species are most at risk. ""Perhaps such fluctuations are not given the attention this paper suggests they ought to give."" ""The passenger pigeon's tale is an interesting one as it points to the catastrophic things that happen when multiple stressors combine.""","Beyond the obvious merits of species discovery (especially for conservation management), this ultimately will also result in phylogenetic and biogeographic analyses that benefit from greater taxonomic sampling, and that are spatially more informative. They argue that two populations separated by a region outside the climatic niche envelope of the two populations makes current gene flow unlikely and thus supports both populations being considered separate species. In cases of divergent ecological niches and a pair of valid 910 SYSTEMATIC BIOLOGY VOL.",[1],Medicine,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1038/s41591-018-0091-x,Medicine_easy_315,"advertisement

The results, published in the journal Nature Medicine, revealed cancer cells are much more reliant on Yin Yang1 than normal cells, and that it may drive breast cancer growth.","Interestingly, LTED cells have an expanded repertoire of ERα binding compared to MCF7, fuelled by endogenous ligands 10 .","Crucially, the findings also reveal how tumours can change their 'appearance' to evade cancer treatments, using a system called epigenetics. advertisement

The results, published in the journal Nature Medicine, revealed cancer cells are much more reliant on Yin Yang1 than normal cells, and that it may drive breast cancer growth. The findings also revealed tumours change which genes they switch on as they become aggressive -- which may affect how they respond to treatment.","YY1positive cells appear to dominate both primary and metastatic lesions in luminal patients, suggesting that this might remain important even after ET ( Fig. Interestingly, LTED cells have an expanded repertoire of ERα binding compared to MCF7, fuelled by endogenous ligands 10 . Nonetheless, YY1 and ERα overlap remains restricted to a minority of sites ( Supplementary Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34627030168&p=1pl&v=1&x=hF9k2ZTU-XUiToM72b9JHA
10.1073/pnas.1403984111,Medicine_easy_316,"John Calvelli, also with the group, said that such occasions help spur legislation to cut down on trade in the material.","Intriguingly, our analysis suggests the rate of killing slowed after the peak in 2011 both locally in Samburu and globally, although it still remained unsustainable.","But various experts at the event said that wasn't the case. John Calvelli, also with the group, said that such occasions help spur legislation to cut down on trade in the material. The event helps show that these dead animal parts have no value, he added.","Although the reliability of any single site estimate by the modeling approach is uncertain, efforts to refine the model to improve accuracy will undoubtedly enhance its utility. Intriguingly, our analysis suggests the rate of killing slowed after the peak in 2011 both locally in Samburu and globally, although it still remained unsustainable. It is critical to identify the drivers of this change in the rate of illegal killing.",[1],Medicine,train,1.0,news,http://www.newsweek.com/us-government-crushed-1-ton-ivory-times-square-345137
10.1016/j.cmet.2015.02.003,Medicine_easy_317,"The natural infection-fighting function of salt accumulation may be largely unnecessary, given the widespread use of antibiotics.",We found that Na + accumulated at the site of bacterial skin infections in humans and in mice.,"""This mostly happens totally independent of the diet."" The natural infection-fighting function of salt accumulation may be largely unnecessary, given the widespread use of antibiotics. The results may also help explain why elderly patients show high concentrations of salt, as salt stores may grow as the aging body deals with more and more instances of inflammation, in response to the maladies of old age like heart disease and cancer.","High-salt diet promotes skin Na + accumulation, which boosts macrophage activation and helps resolve bacterial infection. We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation.",[1],Medicine,train,1.0,news,http://www.upi.com/Science_News/2015/03/03/Scientists-say-salt-may-guard-against-infection/4511425414509/
10.1073/pnas.1214971109,Medicine_easy_318,"To explore this new area, the researcher must expand from the micro- to the nanometric level.","At intermediate densities more compact porous structures are observed, whereas a homogeneous glass emerges when the solute occupies more than 50% of the volume .","""We could apply these methods to a wealth of materials other than gels, foams or inks,"" says Giuseppe Foffi. To explore this new area, the researcher must expand from the micro- to the nanometric level. He also wants to explore ""trigels"" and other ""polygels.""","At low densities, irreversible aggregation leads to fractal gels. At intermediate densities more compact porous structures are observed, whereas a homogeneous glass emerges when the solute occupies more than 50% of the volume . After the quench, the system is thermodynamically unstable and strong density fluctuations set in, favoring the separation of the fluid into two coexisting phases.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2012/11/121105161212.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/srep01456,Medicine_easy_319,"Figuring out the resistance time line, Adelman added, could provide insights about how fast evolution is working in bedbugs and could have implications for the future of bedbug control.",One or both kdr mutations are present in 18 populations tested (Fig.,"An intriguing question raised by the new findings, researchers say, is just when did bedbugs evolve their resistance? Figuring out the resistance time line, Adelman added, could provide insights about how fast evolution is working in bedbugs and could have implications for the future of bedbug control. A New Prescription

Changlu Wang, an entomologist at Rutgers University in New Jersey, said the new findings are already providing valuable clues about how to better handle bedbugs.","An Abc transporter associated mechanism was also detected in all the populations except LEX-5. One or both kdr mutations are present in 18 populations tested (Fig. Out of the marker genes studied, ClCE21331 showed the maximum increase (.50 fold) of gene expression in most field populations (76.2%).",[1],Medicine,train,1.0,news,http://news.nationalgeographic.com/news/2013/13/130314-bedbug-insecticide-resistance-pest-science/
10.1038/nn.3635,Medicine_easy_320,"""This method gives you a visualization of 'when' and 'where' at the same time.","At the subordinate level, we found that visual representations distinguished bodies by species with an onset at 75 ms (64-113 ms) and a peak at 170 ms (104-252 ms), and the MDS showed a clear species-specific clustering of bodies ( Fig.","""This method gives you a visualization of 'when' and 'where' at the same time. However, it works too slowly to keep up with the brain's millisecond-by-millisecond dynamics. It's just pure automatic machinery that starts every time you open your eyes, and it's incredibly fast,"" Cichy says.","2c ) showed a division between faces and bodies, dominated by nonhuman bodies versus the other conditions. At the subordinate level, we found that visual representations distinguished bodies by species with an onset at 75 ms (64-113 ms) and a peak at 170 ms (104-252 ms), and the MDS showed a clear species-specific clustering of bodies ( Fig. We also observed a significant difference in decoding accuracy for human versus nonhuman faces starting at 70 ms (54-74 ms), followed by two prominent peaks at 127 ms (122-133 ms) and 190 ms (175-207 ms, calculated on the time window starting at the trough between the two peaks at 156 ms and 1,200 ms) ( Fig.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04627-5,Medicine_easy_321,"For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said.","In other words, skilled readers benefited slightly from repeated practice with the timed reading tests, while poor readers did not show any improvements with practice and only showed an improvement in performance as a result of the intervention program.","Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said. For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said. But the structure of this experiment underscores the importance of the findings, he added: Children participated in a tightly controlled, short-term educational intervention, with measurable, identifiable growth in brain tissue from start to finish.","Indeed, in a reading-skill-matched subset of the control subjects (n = 9), we detected no change in reading scores over time and significant group-by-time interactions for all of the reading-related measures. In other words, skilled readers benefited slightly from repeated practice with the timed reading tests, while poor readers did not show any improvements with practice and only showed an improvement in performance as a result of the intervention program. In the left AF, we found a significant main effect of group (F(1,125) = 7.047, p = 0.009) but not of time (F(1,125) = 1.033, p = 0.31) and a significant groupby-time interaction (F(1,125) = 4.97, p = 0.028), consistent with a decrease in MD over time that was specific to the intervention subjects.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1016/j.mito.2018.08.001,Medicine_easy_323,"""New treatments might only be given for a short period of time to promote healing, not unlike applying a cast to promote the healing of a broken leg.",This initiates the oxidative shielding response needed for damage control and containment .,"Naviaux suggests science may be on the cusp of writing a second book of medicine, one that focuses on the prevention of chronic illness and new treatments for chronic disease that can help some people recover completely, where old approaches produced only small improvements with symptoms that persisted for life. ""New treatments might only be given for a short period of time to promote healing, not unlike applying a cast to promote the healing of a broken leg. When the cast is removed, the limb is weak, but over time, muscles recover and bone that was once broken may actually be stronger.""","Within minutes, the normal anti-inflammatory M2 form of mitochondria that is specialized to meet the metabolic needs of the differentiated cell, is polarized toward pro-inflammatory, M1 mitochondria (Fig. This initiates the oxidative shielding response needed for damage control and containment . With M1 polarization, energy-coupled mitochondrial oxygen consumption drops, and cellular energy production switches to glycolysis and lactate production.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37052707703&p=1pl&v=1&x=sh4bblHfq4G8CThdM37YaA
10.1111/j.1471-0528.2008.01772.x,Medicine_easy_324,"[18]

How to prevent ovarian cancer

""The most important thing to prevent ovarian cancer is an awareness of your body and family history,"" Dr. Wethington says.","Examination of the variable of abdominal distension and bloating revealed that 38 of the women diagnosed with cancer experienced distension (sensitivity of 86.4%, 95% CI 72.6-94.8%) compared with 38 (47.5%) of those without cancer (specificity of 52.5%, 95% CI 41.0-63.8%).","And if a woman has both ovaries removed and has not undergone menopause, the surgery will cause her to experience premature menopause. [18]

How to prevent ovarian cancer

""The most important thing to prevent ovarian cancer is an awareness of your body and family history,"" Dr. Wethington says. Even if you stop taking them, you still have some benefit from the years you did take them, Dr. Wethington adds.","Intramenstrual bleeding was more prevalent among the noncancer group. Examination of the variable of abdominal distension and bloating revealed that 38 of the women diagnosed with cancer experienced distension (sensitivity of 86.4%, 95% CI 72.6-94.8%) compared with 38 (47.5%) of those without cancer (specificity of 52.5%, 95% CI 41.0-63.8%). In contrast, only two women with cancer experienced abdominal bloating (without distension) (sensitivity of 4.5%, 95% CI 0.6-15.5%) compared with 22 (27.5%) women without cancer (specificity of 72.5%, 95% CI 61.4-81.9%).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39307773432&p=1pl&v=1&x=bXk43UkJ_BFT3HKaYb2PQA
10.1038/s41598-017-18618-x,Medicine_easy_325,Acetic acid influences BRL-3A cell lipid metabolism via AMPK signaling pathway.,The minimum dilution of ACV required for growth inhibition varied for each microbial species.,This study gives good advice about how to stay vigilant over false claims. And that is how I was exposed to the potential of false claims. Acetic acid influences BRL-3A cell lipid metabolism via AMPK signaling pathway.,"The minimum dilution of ACV required for growth inhibition varied for each microbial species. For C. albicans, a 1/2 ACV had the strongest effect, S. aureus, a 1/25 dilution ACV was required, whereas for E-coli cultures, a 1/50 ACV dilution was required (p < 0.05). Monocyte co-culture with microbes alongside ACV resulted in dose dependent downregulation of inflammatory cytokines (TNFα, IL-6).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39098464353&p=1pl&v=1&x=1oF0R8OHMp2RCFFanDJNtw
10.1016/j.mito.2018.08.001,Medicine_easy_326,"When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors.",This switch in bioenergetics is protective to cells when capillaries have been disrupted and the availability of oxygen for aerobic metabolism is compromised.,"A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first. When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors. But the benefits were transient, fading and disappearing as the drug exited their systems.","With M1 polarization, energy-coupled mitochondrial oxygen consumption drops, and cellular energy production switches to glycolysis and lactate production. This switch in bioenergetics is protective to cells when capillaries have been disrupted and the availability of oxygen for aerobic metabolism is compromised. This treatment causes cells to enter CDR1, decreasing mitochondrial oxidative phosphorylation and increasing glycolysis.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ypj94azpXWE/
10.14814/phy2.13617,Medicine_easy_327,"""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said.","For one child, we replaced actigraphic measures with sleep diary data due to noncompliance with wearing the actigraph.","For preschoolers, this may not only lead to trouble falling asleep one night, but to chronic problems feeling sleepy at bedtime. ""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said. The study sample size was small and it used only one intensity of light, 1,000 lux, which is far greater than the intensity of a typical handheld electronic device, she notes.","Of these, 11 children were enrolled and 10 completed the study. For one child, we replaced actigraphic measures with sleep diary data due to noncompliance with wearing the actigraph. The intra and interassay coefficients of variation were 4.1% and 6.6%, respectively.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/preschoolers-exposed-to-nighttime-light-lack-melatonin/
10.1038/ncomms5060,Medicine_easy_328,"(Image: Forschungszentrum Julich) (click on image to enlarge)

In our cells, which contain biopolymer filaments, active flow due to molecular motor proteins can be observed.",The other protein bands between 50-150 kDa were degradation products of TbIAD5-1.,"This finding may explain how other biological as well as man-made filaments flow, which could aid, among other things, the search for renewable alternatives to replace oil-based polymers. (Image: Forschungszentrum Julich) (click on image to enlarge)

In our cells, which contain biopolymer filaments, active flow due to molecular motor proteins can be observed. The viscosity of solutions of semiflexible polymers decreases dramatically at high shear rates a measure of the velocity gradient or the speed differences within a fluid.","3B) , and LC-MS/MS showed that this band represented Tb927.7.920, which encodes a putative inner-arm dynein with a predicted molecular mass of 465 kDa and is one of the two IAD5-family dyneins that share an overall sequence identify of 33.2% . The other protein bands between 50-150 kDa were degradation products of TbIAD5-1. Immunoprecipitation of TbCentrin3::PTP was capable of pulling down TbIAD5-1::3HA from the cell lysate prepared by sonication (Fig.",[1],Medicine,train,1.0,news,http://www.nanowerk.com/nanotechnology-news/newsid=37681.php
10.1073/pnas.1511220112,Medicine_easy_329,They found that modern human shoulders most similarly resemble the orangutans' lateral orientation and the African apes' blade shape.,Later postnatal growth has a relatively limited and similar effect on blade shape across lineages whereas spine angle does not change with age .,"Primitive in some ways, derived in other ways, and different from all of them,"" Young explained in the release. They found that modern human shoulders most similarly resemble the orangutans' lateral orientation and the African apes' blade shape. While the A. afarensis shoulder was most similar to the African ape and the A. sediba shoulder was closer to humans', this positioning confirms that Australopithecus species were able to use sophisticated tools.","Both models posit a series of changes to both the position of the spine and the shape of the blade in multiple lineages. Later postnatal growth has a relatively limited and similar effect on blade shape across lineages whereas spine angle does not change with age . These facts suggest that genetic regulation of the early positioning of muscles, spine, and acromion are critical to establishing species differences rather than later growth or functional remodeling.",[1],Medicine,train,1.0,news,http://www.natureworldnews.com/articles/16572/20150909/ape-human-evolution-more-clues-revealed-shoulders.htm
10.1080/10635150701775111,Medicine_easy_330,"It is nature's fault, too

Zink and his colleagues thought natural fluctuation may have played a role in the bird's extinction.","However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself.","Their excrement was toxic to plants, and when a flock roosted on trees, they could break all the branches through the sheer numbers perching."" It is nature's fault, too

Zink and his colleagues thought natural fluctuation may have played a role in the bird's extinction. They knew that such fluctuations could dramatically reduce population size, and perhaps human exploitation through hunting and trade may have tipped the balance at the wrong time for this species, which could never recover.","Our preliminary analysis based on 12S mtDNA (not shown) finds the Zanzibar specimen falling in a clade with P. ravenala and the other Comoros specimens forming a polytomy with P. dubia from Northwest Madagascar. However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself. Nevertheless, based on the findings of this study, we anticipate that this new application of ecological niche modeling will greatly facilitate species delimitation, and thus also aid the recognition of both additional species diversity and more recent speciation events.",[1],Medicine,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1534/genetics.116.197285,Medicine_easy_331,But organisms use both NHEJ and homology-directed repair.,"2 ), consistent with general results for the probability of adaptation from SGV after an environmental shift [17] .","It's like the perfect template for repairing your 2007 Honda Civic. But organisms use both NHEJ and homology-directed repair. For a CRISPR/Cas9 gene drive to be most effective, it must be ""tuned"" toward homology-directed repair.","Generally, as long as resistance alleles do not carry large costs themselves and provide any fitness advantage over the driver, evolution of resistance from the SGV is practically assured whenever θ > 0.1, whereas it remains unlikely for θ << 0.1 (Fig. 2 ), consistent with general results for the probability of adaptation from SGV after an environmental shift [17] . The likelihood that resistance evolves from de novo mutation also depends strongly on θ, with resistance becoming likely once θ > 1.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1073/pnas.1403984111,Medicine_easy_332,"In this way, he showed that almost all the ivory that's been seized in the last decade has come from just two poaching hotspots--one that includes Gabon and the Congo, and another centered in Tanzania.","More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year.","In this way, he showed that almost all the ivory that's been seized in the last decade has come from just two poaching hotspots--one that includes Gabon and the Congo, and another centered in Tanzania. So, rather than targeting poachers, he says, it's far more efficient to go after their customers. It's likely that these same cartels are funding poachers in the first place.","At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year. Preliminary data from 2013 indicate overharvesting continued.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37151262070&p=1pl&v=1&x=2kcAbHXpIqOOjL4ptCVntA
10.1001/jamaoncol.2018.3701,Medicine_easy_333,"SelectMDx-positive men, who are more likely to benefit from treatment, were five times more likely to receive a biopsy than SelectMDx-negative men.","24 That study found annual expenditures for patients aged 66 to 99 years related to screening to be $447 million in 2009 US dollars, but this did not include costs of treatment and subsequent follow-up, which we found to represent the majority of spending related to prostate cancer detection.","SelectMDx was shown to have a significant impact on initial prostate biopsy decision-making. SelectMDx-positive men, who are more likely to benefit from treatment, were five times more likely to receive a biopsy than SelectMDx-negative men. In the subset of patients biopsied within three months of receiving test results, high-grade cancers were discovered only in the SelectMDx-positive men, with none of the SelectMDx-negative patients biopsied within three months of testing being diagnosed with a clinically-significant disease.","In contrast, the microcosting approach of the present study did not require a comparison sample of noncancer patients and additionally enabled detailed calculations of costs attributable to different categories of care. 24 That study found annual expenditures for patients aged 66 to 99 years related to screening to be $447 million in 2009 US dollars, but this did not include costs of treatment and subsequent follow-up, which we found to represent the majority of spending related to prostate cancer detection. Overall, our findings were consistent with this prior study.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37616037423&p=1pl&v=1&x=gXp7O7pmGkPY1w04wbVK7A
10.1038/s41467-018-07557-4,Medicine_easy_334,The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change.,"1 ), the regional differences appear less pronounced ( Fig.","""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change. ""The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved,"" the authors write.","However, acknowledging a broader spectrum of factors known to contribute to the hazard level ( Supplementary Fig. 1 ), the regional differences appear less pronounced ( Fig. For example, our results highlight critical areas such as the Pechora region, the northwestern parts of the Ural Mountains, northwest and central Siberia, the Yakutsk basin (except for the city of Yakutsk in low to moderate hazard area), as well as the central and western parts of Alaska to which high priority for local scale infrastructure hazard assessments should be performed in future decades 1 .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37952353365&p=1pl&v=1&x=z8k6aIsKNtvV0TWFOzO7Gg
10.1016/j.cub.2013.09.038,Medicine_easy_335,It gave us unique insights into the potentially key role disassembling cilia have in deciding the tails' length.,"Similar to previous results with wild-type cells , we consistently observed that in adf1-6 cells, the remaining flagellum resorbed during the initial phase of regrowth of the shed flagellum ( Figure 2E ).","They were unlike anything anyone had ever seen before. It gave us unique insights into the potentially key role disassembling cilia have in deciding the tails' length. Further investigation will help us understand how ciliary malfunction causes a progression of diseases.""","This phenomenon is most apparent in a ''long-zero'' experiment: when one flagellum is amputated and the other is full length, the long flagellum resorbs as the zero-length flagellum regenerates, and once they are equal in length, they continue to regenerate together until both flagella are full length again . Similar to previous results with wild-type cells , we consistently observed that in adf1-6 cells, the remaining flagellum resorbed during the initial phase of regrowth of the shed flagellum ( Figure 2E ). We did not observe any abnormal behavior such as overshoot (data not shown).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131031124920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aap7778,Medicine_easy_337,"This analyses the natural decay of uranium in minerals that build up over cave paintings, providing surprisingly specific results.","For subsamples in all locations, the expected depth-age consistency was confirmed.","The issue was technology. This analyses the natural decay of uranium in minerals that build up over cave paintings, providing surprisingly specific results. Rather than providing answers within a millenium-sized ballpark, for example, uranium-thorium dating can pin materials to specific centuries.","In Maltravieso ( fig. For subsamples in all locations, the expected depth-age consistency was confirmed. The oldest date provides a minimum age of 66.7 ka (MAL 13) (Table 1 ) for the hand stencil.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33376300846&p=1pl&v=1&x=Ak0UjVbeV1ss5tQU-rQsig
10.1016/j.neuron.2017.06.028,Medicine_easy_338,These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories.,"Specifically, these properties seem to depend on BCAN expression in PV+ interneurons, as the PV+ cell-specific knockdown revealed a particularly strong and broad phenotype when compared to the full Bcan knockout that might be explained by the different timing of the experimental manipulations.","The researchers also found that this protein shapes the intrinsic properties of PV+ interneurons and sculpts their connections to other neurons. These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories. When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London.","Indeed, the changes in spike shape and Kv3.1b clustering appear more directly related with the absence of BCAN. Specifically, these properties seem to depend on BCAN expression in PV+ interneurons, as the PV+ cell-specific knockdown revealed a particularly strong and broad phenotype when compared to the full Bcan knockout that might be explained by the different timing of the experimental manipulations. Likewise, the first PNNs are observed around P7 and their maturation continues until P28 .",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1016/j.neuron.2017.06.028,Medicine_easy_339,"As such, unravelling key molecular players in this form of plasticity may pave the way for new treatments.",GluA1 mutants also exhibit impaired short-term spatial memory .,"The findings are published in the journal Neuron and have the potential to reveal new therapeutic strategies for neurological and psychiatric disorders. As such, unravelling key molecular players in this form of plasticity may pave the way for new treatments. The researchers also found that this protein shapes the intrinsic properties of PV+ interneurons and sculpts their connections to other neurons.","We assessed spatial working memory on the T-maze and found a moderate impairment in Bcan mutant mice ( Figures 8A and 8B ) that resembles the phenotype of mice lacking GluA1 in PV+ cells . GluA1 mutants also exhibit impaired short-term spatial memory . As expected, control mice showed a strong preference for the novel arm ( Figures 8E-8H ).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1016/j.cell.2018.04.038,Medicine_easy_340,"Knowing that may lead to the development of new drugs that target specific parts of the enzyme.""","In total, 20,400 movies of the DNA-bound telomerase sample and 12,344 movies of the DNA-free telomerase sample were acquired for the structures presented in this paper.","""At each step, we zoom in closer and see more and more details, and can now begin to deduce not just what the enzyme looks like, but also how it functions. Knowing that may lead to the development of new drugs that target specific parts of the enzyme."" In addition to reporting the highest level of detail ever seen of the structure of telomerase's catalytic core, shown in the animation below, the researchers report for the first time they have captured telomerase in the process of making DNA.","Because the human TERT-TER catalytic core and IFD-TRAP-TEN-TPP1-POT1 interactions are expected to be similar to corresponding interactions in Tetrahymena , this first complete model of a telomerase with bound DNA and sstDNA-handling proteins also provides unprecedented insight into human telomerase mechanism, mutations that affect function, and recruitment to telomeres and a framework for design of telomerase targeting therapeutics. In total, 20,400 movies of the DNA-bound telomerase sample and 12,344 movies of the DNA-free telomerase sample were acquired for the structures presented in this paper. Notably, as discussed below, most of the particles were considered as ''bad'' particles during 2D and 3D classifications and therefore discarded.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1016/j.ijheh.2018.01.004,Medicine_easy_341,"O Actively engage with local communities, healthcare users, frontline health workers and vulnerable groups to ensure that progress towards better health systems is socially inclusive and responsive to the needs of everyone, leaving no one behind.",authority operating the facility) differed by country.,"Drawing on examples of WaterAid's work in healthcare facilities from Cambodia to Nicaragua, Myanmar to Malawi Transforming Health Systems makes a series of recommendations to health ministries in order to address the crisis faced by healthcare facilities globally, including:

O Embed the need for water, sanitation and hygiene in healthcare facilities as a core priority for investment across all relevant health efforts, including maternal and newborn health, tackling antimicrobial resistance, health emergency preparedness, infection prevention and control, sexual and reproductive health and rights, quality of care and plans for achieving Universal Health Coverage. O Actively engage with local communities, healthcare users, frontline health workers and vulnerable groups to ensure that progress towards better health systems is socially inclusive and responsive to the needs of everyone, leaving no one behind. O Put in place national minimum standards for water, sanitation and hygiene in all government and private healthcare settings, and ensure these are adhered to, with improvement plans and the necessary investment put in place where needed.","The relationship was significant in the multivariable models of Haiti, Malawi, Senegal, and Tanzania. authority operating the facility) differed by country. In univariable regression in Bangladesh, Haiti, Malawi, and Nepal, NGO-managed HCFs had significantly higher odds of having a basic water service as compared to governmentmanaged facilities (no NGO facility categorization was used in the Senegal and Tanzania datasets).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34104392589&p=1pl&v=1&x=fUbOLvAgGSdkdG9TgkDIzg
10.1098/rsos.171474,Medicine_easy_342,"Mass shooters killed 31 people last weekend in El Paso and Dayton, Ohio, and three people in Gilroy, California, last month, including two children.","Instead, we argue that mere exposure to, and enactment of, putatively violent virtual acts in gaming contexts in aggregate is unlikely, on its own, to bear positively on perceivable differences in adolescents' aggression in real-world settings.","Mass shooters killed 31 people last weekend in El Paso and Dayton, Ohio, and three people in Gilroy, California, last month, including two children. The week was the deadliest for mass shootings and fatalities this year, whichever way one chooses to count them. Based on what their analyses revealed, here are five common misconceptions about the perpetrators of mass shootings:

Myth: Mass shooters have a specific profile that can be easily spotted ahead of time.","These topics provide promising avenues for inquiry and have direct implications for literature focused on antisocial behaviours such as bullying, trolling and griefing . Instead, we argue that mere exposure to, and enactment of, putatively violent virtual acts in gaming contexts in aggregate is unlikely, on its own, to bear positively on perceivable differences in adolescents' aggression in real-world settings. Further, this is not to say that we could rule out a correlation between every operationalization of gaming and every measure of adolescents' violent behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882736616&p=1pl&v=1&x=QLA1HMQhScCizGL1drmq5A
10.1001/jamapsychiatry.2015.0500,Medicine_easy_343,"""Guidelines and clinical wisdom suggest that you really should be using a high degree of caution and only using them when other treatments have failed, as a last resort.""","41 In our study, among adolescents treated with antipsychotics who had diagnosed psychiatric disorders, the most common diagnoses were ADHD (34.9%), followed by depression (24.4%) and bipolar disorder (20.5%).","""Guidelines and clinical wisdom suggest that you really should be using a high degree of caution and only using them when other treatments have failed, as a last resort."" Teens were most likely to be prescribed antipsychotics, with 1.19 percent getting the drugs in 2010, compared to 0.11 percent in younger children. Boys were more likely to be given the medications.","Stimulant prescriptions and ADHD diagnoses peaked among older children, while antidepressant prescriptions and depression diagnoses increased during adolescence. 41 In our study, among adolescents treated with antipsychotics who had diagnosed psychiatric disorders, the most common diagnoses were ADHD (34.9%), followed by depression (24.4%) and bipolar disorder (20.5%). In the community, the prevalence of adolescents with severe impairment is 8.7% for depression, 4.3% for ADHD, and 2.6% for bipolar disorder.",[1],Medicine,train,1.0,news,http://www.npr.org/sections/health-shots/2015/07/01/418935734/antipsychotics-too-often-prescribed-for-aggression-in-children
10.1136/bmjopen-2014-006648,Medicine_easy_344,But the social care costs of dementia outweighed the social care costs of the other three conditions combined.,A total of 15 773 charities were identified through the Charity Commission as potentially funding medical research.,"The costs of healthcare were highest for cancer (PS4.4 billion) and lowest for dementia at PS1.4 billion and for stroke at PS1.8 billion. But the social care costs of dementia outweighed the social care costs of the other three conditions combined. And the combined costs of health and social care for dementia came to PS11.6 billion in 2012, the researchers calculated.","Of these charities, 51 (42%) were included in the analysis. A total of 15 773 charities were identified through the Charity Commission as potentially funding medical research. Owing to the very high number of charities identified, we only included the first 214 representing 75% of the total combined income.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150413213252.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.neuron.2018.12.026,Medicine_easy_347,"""Changes in the excitation-inhibition ratio might be successfully compensating to maintain a relatively normal firing rate, but a side effect of that compensation may be that they degrade the precision of the coding information,"" he suggests.",There were no significant differences between any ASD mutant and its WT.,"But decreased inhibition may have unwanted secondary effects that impair other aspects of neural information processing, such as the tuning each neuron has to specific stimuli. ""Changes in the excitation-inhibition ratio might be successfully compensating to maintain a relatively normal firing rate, but a side effect of that compensation may be that they degrade the precision of the coding information,"" he suggests. ""So even though there are not more spikes, the spiking could encode information less precisely.""","In all mutants, this lies within 0.5 mV of the PSP stability contour. There were no significant differences between any ASD mutant and its WT. This common reduction in whisker-evoked spiking of L2/3 FS neurons suggests that feedforward inhibition is reduced in vivo.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1186/s13059-018-1434-0,Medicine_easy_348,"Interdisciplinarity and collaboration are the key success factors

This work, which has been published in Genome Biology, shows how interdisciplinary research pushes the boundaries of knowledge and contributes to finding new insights for improving health.","Interestingly, AP-1 is essential for MHC complex I downregulation and immune escape upon HIV infection .","""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities."" Interdisciplinarity and collaboration are the key success factors

This work, which has been published in Genome Biology, shows how interdisciplinary research pushes the boundaries of knowledge and contributes to finding new insights for improving health. This is a new example on how interdisciplinarity may lead to new insights in cancer genomics and provides new tools for cancer research.","AP1B1 (d N / d S = 0.41, Q = 0.039) and AP2S1 (d N /d S = 0.04, Q = 0.01) are members of the clathrin-associated adaptor protein complex 1 (AP-1) and 2 (AP-2), respectively, which are involved in antigen loading onto the MHC class II complex . Interestingly, AP-1 is essential for MHC complex I downregulation and immune escape upon HIV infection . In summary, the presented evidence supports a major role of negative selection in cancer evolution, which has been neglected in most studies, and ultimately challenges the current paradigm of an exclusive role of positive selection in cancer.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1186/s13229-018-0246-0,Medicine_easy_349,"In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","It is important for national policy to report data from these first three cities, and our on-going data collection in the seven other cities will serve to further inform national policy and future research directions.","In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","First, according to the recruitment criteria, the sample for the cities was representative for the local region but is not yet nationally representative of China; hence, the hope for the China SCORE project is to map autism prevalence in 10 cities in total. It is important for national policy to report data from these first three cities, and our on-going data collection in the seven other cities will serve to further inform national policy and future research directions. The participation rate of the communities in this study is much higher than most of the prevalence studies of autism internationally.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1038/s41467-018-04906-1,Medicine_easy_350,"According to the research paper, the sensor developed by the team ""can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display,"" and at a resolution that satisfies FBI security standards.",These invisible percolative networks exhibit excellent optoelectronic properties (R s of~1.03 Ω/sq T of 91.04% in the visible light region) and outstanding reliability against mechanical bending.,"Getty Images

Forget fingerprint scanners tucked away on the back of your phone or beneath a home button -- your next smartphone is probably going to have a fingerprint sensor under the screen that measures your temperature, just to make sure you're a real human. According to the research paper, the sensor developed by the team ""can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display,"" and at a resolution that satisfies FBI security standards. Don't expect the new sensor to detect a fever through your finger just yet -- the temperature sensor is designed to detect human skin temperature to make sure you're not using a fake hand or artificial fingerprint to spoof security.","As a result, the capacitance change between fingerprint ridges and valleys is very low. These invisible percolative networks exhibit excellent optoelectronic properties (R s of~1.03 Ω/sq T of 91.04% in the visible light region) and outstanding reliability against mechanical bending. In addition, the fingerprint sensor using the AgNF-AgNW hybrid electrode has high resolution (318 capacitors per inch (CPI)) with good transparency (89.05%).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34461950539&p=1pl&v=1&x=XLGqlDf_Oo7GWj0vCJKGfw
10.1038/s41467-018-05229-x,Medicine_easy_351,"The short-lived Wannier-Stark localization correlates with drastic changes to the electronic structure of the crystal and results, for example, in extremely high optical nonlinearity.","The situation changes drastically when considering bulk solids, where D is in the order of the lattice constant a ≈5 Å and Δ ≈1 eV, resulting in E WSL ≈20 MV/ cm, which is far above the typical breakdown field of dielectrics under stationary bias.","""If the electric field inside the crystal is strong enough, the electronic states can be localized to a few atoms. The short-lived Wannier-Stark localization correlates with drastic changes to the electronic structure of the crystal and results, for example, in extremely high optical nonlinearity. The first-ever experimental realization of Wannier-Stark localization in a gallium arsenide crystal was made possible through highly intense Terahertz radiation with field intensities of more than ten million volts per centimetre.","Such an electric field is easily sustained by typical semiconductor devices. The situation changes drastically when considering bulk solids, where D is in the order of the lattice constant a ≈5 Å and Δ ≈1 eV, resulting in E WSL ≈20 MV/ cm, which is far above the typical breakdown field of dielectrics under stationary bias. In contrast to superlattices where localization concerns only the envelope wave functions of electrons in the modulated compound structure, such Wannier-Stark quantization in a bulk material would result in strong distortions of the electronic system on the level of a single unit cell, equivalent e.g., to a significant change of interatomic chemical bonds.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1038/s41598-018-30656-7,Medicine_easy_352,But the team thinks that the crowsa natural propensity to use tools and their ability to determine which objects can be used as tools certainly help.,"In theory, the presence of multiple nest sites could enhance competition between scouts and lead to longer decision times, but this does not occur in our data.","When the scientists made the task more difficult by supplying three or four combinable parts, Mango was the only one that figured it out. But the team thinks that the crowsa natural propensity to use tools and their ability to determine which objects can be used as tools certainly help. In other words, they may play out the potential steps in their brain before settling on a viable solution they can perform.","For example, inhibitory interactions, in which a scout committed to one site diminishes the effectiveness of recruiters to competing sites, could produce the time cost at the heart of choice overload and predicted by the ToW model. In theory, the presence of multiple nest sites could enhance competition between scouts and lead to longer decision times, but this does not occur in our data. The decision latency evidence presented here does not support a role for such inhibitory interactions, but it would be premature to conclude that these ants do not use these pheromones or some other inhibitory signal.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37498408749&p=1pl&v=1&x=JzrzVk7uH3JlDWFg7C-bNg
10.1016/j.immuni.2019.05.007,Medicine_easy_353,A research discovery at UNC-Chapel Hill could help tackle stomach flu.,Pre-existing and emergent antibodies displayed similar somatic hypermutation profiles ( Figure 1E ).,"We may be closer than ever to ending those miserable days of vomiting, diarrhea and harsh fever after eating contaminated food or shaking the wrong person's hand. A research discovery at UNC-Chapel Hill could help tackle stomach flu. Local news has never been more important To support vital, local reporting like the coronavirus coverage, please sign up for a digital subscription to charlotteobserver.com #readlocal

Norovirus causes more than 200,000 deaths, mostly young children and elderly, around the world each year, according to the Centers for Disease Control and Prevention.","The low level of emergent antibodies in donor C, who had the highest pre-vaccination titer, is consistent with the strong inverse correlation between day 0 serum titer and the number of emergent antibody clonotypes in the serological memory after immunization with the seasonal influenza vaccine (Lee et al., 2016) . Pre-existing and emergent antibodies displayed similar somatic hypermutation profiles ( Figure 1E ). Although emergent Table S1 .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39573303215&p=1pl&v=1&x=LZ9cWPbe63hLu_eeKZOP_g
10.1098/rsos.171474,Medicine_easy_355,"In its study, the FBI found that most shooters didn't research target locations.","Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function.","The FBI researched 34 active shootings between 2000 and 2013 and found that in 77% of the cases, the subject spent a week or longer planning the attack. In its study, the FBI found that most shooters didn't research target locations. Often, the shooters were already familiar with their intended target, such as their school or office.","The discussion presents an interpretation of this pattern of effects in terms of both the ongoing scientific and policy debates around violent video games, and emerging standards for robust evidence-based policy concerning young people's technology use. Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function. There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39882736616&p=1pl&v=1&x=QLA1HMQhScCizGL1drmq5A
10.1038/s41598-018-20760-z,Medicine_easy_356,"""The most difficult part of this research was how to control the growth and direction of SDS ribbons with precision,"" says Hong.",S5 for details) .,"Therefore, the molecules adsorbed with small angles to the AFM tip scan direction act as the nuclei and grow to become the SDS ribbon. ""The most difficult part of this research was how to control the growth and direction of SDS ribbons with precision,"" says Hong. ""Once the SDS ribbons were grown, their orientations did not change under the AFM scanning conditions.","In general, the AFM tip scanning induces a finite frictional dragging force between the tip and the surface molecules because of microscopic shear flow or because of direct contact between the tip and the molecules . S5 for details) . The destabilization energy shows a quadratic dependence on both of the translational shifts, which means that the SDS molecules are stable against a small translational shift both along and perpendicular to the zigzag direction.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33624582612&p=1pl&v=1&x=OROGVuUGDgkWIep8DYDL5w
10.1073/pnas.1601081113,Medicine_easy_357,"""Perhaps these giant animals were already teetering on the edge of extinction, and humans were just the straw that broke the camel's back,"" Yoder said.","These fragments thus might be described as ""museums"" of genetic diversity within an otherwise desolated grassland savanna.","This intermittent forest corridor made it possible for tree-dwelling mouse lemurs and other forest animals to intermingle and move from one side of the island to the other until about 55,000 years ago, when a hot dry period caused their forest habitat to retreat once again. The research could help shed light on why extinct animals like the 350-pound giant lemurs and the 10-foot-tall elephant birds all died out within a thousand years of human arrival. ""Perhaps these giant animals were already teetering on the edge of extinction, and humans were just the straw that broke the camel's back,"" Yoder said.","Taking this hypothesis to its logical extreme, patterns of genetic diversity within and among these relictual habitats thus might share a signature of genetic diversification driven by long-term isolation but punctuated by periods of gene flow. These fragments thus might be described as ""museums"" of genetic diversity within an otherwise desolated grassland savanna. There were 1,583 SNPs without any missing data across the four taxa (M. lehilahytsara, M. rufus, M. myoxinus, and M. mittermeieri).",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/41GB1vb0sOU/
10.1098/rsos.171474,Medicine_easy_360,"In one incident in November, a youngster reportedly killed his friend with a shotgun in Erbil province while recreating a PUBG scene.",Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours.,"The draft is currently awaiting revision by parliament's speaker. In one incident in November, a youngster reportedly killed his friend with a shotgun in Erbil province while recreating a PUBG scene. However, youths see it as a way to stay safe from the violence outside.","Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers. Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours. In other words, we found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39008420426&p=1pl&v=1&x=Y9M61MqnjfzY0SC9noiwvw
10.1016/j.cub.2013.09.038,Medicine_easy_361,They were unlike anything anyone had ever seen before.,"Using this antibody in western blots, CNK2 protein was not detectable in whole-cell extracts of wild-type cells (data not shown), but a band of 72 kDa, the predicted size of CNK2, was detectable in flagellar extracts.","""We knew that we had something important when we saw that cells bearing mutations in both CNK2 and LF4 had the most extraordinarily long cilia. They were unlike anything anyone had ever seen before. It gave us unique insights into the potentially key role disassembling cilia have in deciding the tails' length.","Sequencing of this PCR product revealed that the 5 0 end of the insertion also lies within the first CNK2 intron in the 5 0 UTR ( Figure 1A ). Using this antibody in western blots, CNK2 protein was not detectable in whole-cell extracts of wild-type cells (data not shown), but a band of 72 kDa, the predicted size of CNK2, was detectable in flagellar extracts. This band was not present in cnk2-1 flagellar extracts, and we concluded that the antibody is specifically recognizing CNK2 and that cnk2-1 is null for protein expression ( Figure 1B ).",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131031124920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1411728112,Medicine_easy_362,It's possible we will find all the coins landing tails.,"However, let us note, that we might borrow a noisy version of |0 0| namely (1 − )|0 0| + |1 1|.","However, this is not true when tossing the coin just a few times. It's possible we will find all the coins landing tails. ""We can use tools from quantum information theory to understand the case when we don't have a large number of particles.""","and by Theorem 18 we can transform the state ρ S ⊗ |0 0| into arbitrary good version of ρ S ⊗ |0 0|. However, let us note, that we might borrow a noisy version of |0 0| namely (1 − )|0 0| + |1 1|. It costs a finite amount of work to create it from the thermal state.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150209161417.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1038/s41598-018-29793-w,Medicine_easy_363,These results suggest that nasal microbiota influences the host response to rhinovirus infection.,"Anyhow, few differences between the clusters were detected.","In general, subjects having Staphyloccocus, and Corynebacterium/Alloiococcus types had lower inflammatory responses and Pseudomonadaceae/Mixed type had lower viral load than other types. These results suggest that nasal microbiota influences the host response to rhinovirus infection. Importantly, changes in the response were reflected in cold symptoms and showed that subjects with Corynebacterium/Alloiococcus nasal microbiota type had lower symptom scores than Staphylococcus or Pseudomonadaceae/Mixed types.","Overall the D0 cluster effect on total symptom scores did not reach statistical significance (P = 0.06). Anyhow, few differences between the clusters were detected. WURSS-21 score, including functional and symptom scores, was lower in Cor/All cluster compared to Staph (P = 0.031) and Ps/Mix clusters (P = 0.026) (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37212363335&p=1pl&v=1&x=sLcdfRtU-o1Jl6n2DiKDzQ
10.1038/ncomms5060,Medicine_easy_364,"They found that filaments have an irregular configuration and are intricately entwined with each other while at rest, but that they form hairpin-like structures and detach themselves completely from one another when in flow.","However, these RNAi-induced cells appeared to lose motility in the culture medium as observed under a light microscope.","The viscosity of solutions of semiflexible polymers decreases dramatically at high shear rates a measure of the velocity gradient or the speed differences within a fluid. They found that filaments have an irregular configuration and are intricately entwined with each other while at rest, but that they form hairpin-like structures and detach themselves completely from one another when in flow. The filaments can then freely slide over each other, which causes the dramatic shear-thinning of semiflexible polymer solutions.","Depletion of TbCentrin3 only slightly slowed down cell growth (Fig. However, these RNAi-induced cells appeared to lose motility in the culture medium as observed under a light microscope. Loss of cell motility occurred at as early as day 1 of RNAi induction, and at day 3 of RNAi all cells lost motility.",[1],Medicine,train,1.0,news,http://www.bio-medicine.org/biology-news-1/Of-bio-hairpins-and-polymer-spaghetti-38373-1/
10.1152/ajpregu.00204.2013,Medicine_easy_365,"Although toxic at high levels, low levels of CO are produced naturally by the body and have positive effects.","Further, exposure to 250 ppm CO led to maternal mouse CO levels of 12.65% COHb, similar to maternal %COHb levels in women who smoke roughly a pack of cigarettes per day during pregnancy; measured in our laboratory as high as 9.85% COHb (unpublished data) and by others as 14% COHb .","The study also suggests a therapy that could offer similar protection against PE with none of smoking's well-known risks. Although toxic at high levels, low levels of CO are produced naturally by the body and have positive effects. This study, the first to look at the effects of CO on the placenta in mice, found that exposing the animals to inhalable CO increased blood flow and vascular growth in the developing placenta, created more, bigger, and stronger connections to the mother's uterus, a process that provides more oxygen and nutrients to the fetus.","Therefore, it is possible that elevated CO levels in women who smoke during pregnancy may contribute to the reduced risk of developing PE. Further, exposure to 250 ppm CO led to maternal mouse CO levels of 12.65% COHb, similar to maternal %COHb levels in women who smoke roughly a pack of cigarettes per day during pregnancy; measured in our laboratory as high as 9.85% COHb (unpublished data) and by others as 14% COHb . We demonstrated that maternal chronic exposure to 250 ppm CO throughout pregnancy increases placental Fig.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/09/130919154253.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-018-04355-w,Medicine_easy_367,"In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes.","Intense membranous CD14 staining was predominately found on tumor-infiltrating leukocytes, and rarely on cancer cells ( Supplementary Fig.","""The way that these immune cells promote lung cancer metastases was very unexpected. In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes. ""It's important to understand that while there is so much focus on activating parts of the immune system to attack cancer, there is also a 'Jekyll and Hyde' process going on in most tumors,"" Pecot said.","We found an impressive dynamic range of expression for CD14 and these chemokines by subtype, with the Basal and Secretory subtypes consistently having the highest levels (Fig. Intense membranous CD14 staining was predominately found on tumor-infiltrating leukocytes, and rarely on cancer cells ( Supplementary Fig. Consistent with RNA-seq data, CD14 protein expression correlated with subtype, and the Secretory subtype displayed the highest levels, followed by Basal ( Supplementary Fig.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/by-forming-clots-in-tumors-immune-cell-aids-lung-cancers-spread/
10.1016/j.neuron.2017.06.028,Medicine_easy_368,The researchers also found that this protein shapes the intrinsic properties of PV+ interneurons and sculpts their connections to other neurons.,"The two-color radial distribution analysis of Brevican with respect to Bassoon ( Figure S1R ) or Homer1 ( Figure S1S ) was done correspondingly, except that in the latter case the mean x,y position of Homer1 localizations was used to establish x,y = 0,0.","As such, unravelling key molecular players in this form of plasticity may pave the way for new treatments. The researchers also found that this protein shapes the intrinsic properties of PV+ interneurons and sculpts their connections to other neurons. These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories.","The z stability was better than ± 10 nm over several hours. The two-color radial distribution analysis of Brevican with respect to Bassoon ( Figure S1R ) or Homer1 ( Figure S1S ) was done correspondingly, except that in the latter case the mean x,y position of Homer1 localizations was used to establish x,y = 0,0. The ssDNA primers to generate the shBCAN (5 0 -CTAGGCAAG CAGAACCGCTTCAATGCCTGACCCACATTGAAGCGGTTCTGTTGCTTTTTG-3 0 and 3 0 -AATTCAAAAAGCAAGCAGAACCGCTTCA ATGTGGGTC AGGCATTGAAGCGGTTCTGCTTGC-5 0 ) were obtained using the Block-it RNAi web tool (Thermo Scientific).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1038/s41598-018-26198-7,Medicine_easy_369,"The authors point out that diminished cytotoxic immunity is a mechanism that underpins the state of T-cell exhaustion in cancer, and is linked with lower levels of effector cytokines and the presence of inhibitor receptors on T cells, which permits tolerance to the cancer cells.","Another important consideration is that, in this study, stretching was performed for 10 minutes once a day at ~25% strain, and we do not know whether a lower ""dose"" of stretching could be equally effective.","Stretching was in addition more specifically found to increase the number of INF-g+ CD4+ T cells within the inflammatory lesion, within just days. The authors point out that diminished cytotoxic immunity is a mechanism that underpins the state of T-cell exhaustion in cancer, and is linked with lower levels of effector cytokines and the presence of inhibitor receptors on T cells, which permits tolerance to the cancer cells. ""Because INF-g is one of the key effector cytokines in cytotoxic immune responses, these results support a role for stretching in promoting TH-1 cytotoxic immunity,"" they note.","Because stretching tissues in one dimension likely results in some amount of perpendicular compression, this question is relevant to our model and will need to be examined. Another important consideration is that, in this study, stretching was performed for 10 minutes once a day at ~25% strain, and we do not know whether a lower ""dose"" of stretching could be equally effective. Determining the minimum effective amplitude, duration and frequency of stretching in animals will be important before translational studies in humans can be undertaken.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34125675804&p=1pl&v=1&x=EIuTbzUDbEKkr7kvXb-kdg
10.1038/s41589-018-0155-8,Medicine_easy_372,"The rise wasn't as great as that seen in the ABHD12-knockout mice, and even four weeks of treatment with the inhibitor appeared to cause only slight hearing defects -- nothing like the profound defects experienced by PHARC patients.",5 ).,"The team found that in adult mice, reducing ABHD12 activity with the inhibitor led to a rise in lyso-PS in immune cells called macrophages, as well as in brain tissue. The rise wasn't as great as that seen in the ABHD12-knockout mice, and even four weeks of treatment with the inhibitor appeared to cause only slight hearing defects -- nothing like the profound defects experienced by PHARC patients. However, in further experiments conducted by the laboratory of study co-senior author John Teijaro, an assistant professor in the Department of Immunology and Microbiology at Scripps Research, it was clear that the reduction in ABHD12 activity had a big effect on the mouse immune system.","1e and Supplementary Fig. 5 ). In contrast, we prepared an authentic sample of the semithiocarbazide (termed DO127 ) and found that it showed no activity against ABHD12 ( Supplementary Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/s41467-019-09863-x,Medicine_easy_374,"In both cases, the primary driver behind the additional costs is the emitted permafrost carbon.",They fall outside the range covered by the SSPW and RCPW pairs described above.,"In both cases, the primary driver behind the additional costs is the emitted permafrost carbon. The interdisciplinary research team hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios and help guide policy-makers towards prudent decisions on emissions reduction targets. ""These two components are set to peak for global temperatures within the range covered by the Paris Agreement, but if the climate warms further, the summer and spring sea ice and land snow covers will retreat further north and the albedo feedback will actually weaken.","The 1.5°C and 2°C scenarios, defined as having a 50% chance of keeping the GMST rise in 2100 below the 1.5°C and 2°C targets based on PAGE-ICE simulations, require extra abatement relative to RCP2.6. They fall outside the range covered by the SSPW and RCPW pairs described above. We, therefore, introduced an additional abatement rate relative to RCP2.6, the same for all the major GHGs represented in PAGE-ICE, and employed Risk Optimiser to find that it is equal to 0.24% per year for the 2°C target and 4.05% per year for the 2°C target scenario.",[1],Medicine,train,1.0,news,https://www.sciencedaily.com/releases/2019/04/190423114027.htm
10.1038/s41467-019-09863-x,Medicine_easy_375,"Even with supercomputers, the number crunching took weeks because the vast geography and complex climate interactions of the Arctic throw up multiple variables.","Nevertheless, under all scenarios, the predominantly warmer future climate associated with the nonlinear PCF and SAF relative to their legacy values translates into marginal increases in the total discounted economic effect of climate change.","It shows how destabilised natural systems will worsen the problem caused by man-made emissions, making it more difficult and expensive to solve. Even with supercomputers, the number crunching took weeks because the vast geography and complex climate interactions of the Arctic throw up multiple variables. So far the impact is small.","For high emissions scenarios, the strength of the PCF saturates, and the weakening SAF gradually cancels the warming effect of the PCF; for BaU, this takes place from the second half of the 22nd century onwards. Nevertheless, under all scenarios, the predominantly warmer future climate associated with the nonlinear PCF and SAF relative to their legacy values translates into marginal increases in the total discounted economic effect of climate change. These increases, which are significant for all scenarios except for BaU, occur through additional temperaturedriven impacts on economy, ecosystems and human health, additional impacts from sea level rise, as well as highly uncertain extra impacts from social discontinuities and climate tipping elements other than the PCF and SAF.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39105856338&p=1pl&v=1&x=Ev5nvBW8jFG5yhRKbQsfjQ
10.1098/rsos.171474,Medicine_easy_376,"It will still be available this weekend on ESPN's digital channels, including its app.",It is possible that the retrospective month-long 'snap shot' this study uses missed a critical dynamic which develops over repeated engagement with video games.,"The decision comes in the wake of the two shootings that prompted politicians, including President Donald Trump, to say video games that glorify violence could be contributing to the country's shooting epidemic. It will still be available this weekend on ESPN's digital channels, including its app. ""Blaming video games is a 'look over there' move instead of a 'look at ourselves' reflection.","This could provide a context to understand gaming effects set against a rich data milieu, including information on objective gaming behaviours, social, familial, school, individual and genetic level factors. It is possible that the retrospective month-long 'snap shot' this study uses missed a critical dynamic which develops over repeated engagement with video games. To this end, field or natural experiments using multi-wave random-intercepts cross-lagged panel modelling should follow the present work to provide an expanded test of the effects of violent gaming on human behaviour.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39907846044&p=1pl&v=1&x=qR_l8J7Kj5CPAEm_xm1uww
10.1111/cdev.12370,Medicine_easy_378,"Regulating emotions

Young people who reflected on their experiences from a self-distanced perspective became less upset than those who reflected from a self-immersed perspective, according to the study in Child Development.","(1 = right now, 7 = a long time ago).","Regulating emotions

Young people who reflected on their experiences from a self-distanced perspective became less upset than those who reflected from a self-immersed perspective, according to the study in Child Development. In part, this was because adolescents who saw their experience from a distance thought about it differently. These teens were more likely to reconsider the events in meaningful and insightful ways and less likely to simply replay the upsetting events in their minds.","(1 = very real, 7 = very imagined). (1 = right now, 7 = a long time ago). We averaged ratings on these four questions to compute a spontaneous distancing composite score (a = .60, M = 3.58, SD = 1.24.",[1],Medicine,train,1.0,news,http://www.futurity.org/teens-emotions-distance-903192/
10.1038/s41467-018-05242-0,Medicine_easy_379,"The study is published in Nature Communications and the researchers believe their discovery could lead to new drugs against infection and inflammation, for example in wound healing.",This LPS concentration corresponds to saturation in the LPS adsorption isotherm under these conditions.,"The study is published in Nature Communications and the researchers believe their discovery could lead to new drugs against infection and inflammation, for example in wound healing. This will become a new way of preventing both infection and inflammation without using antibiotics.""","In brief, by monitoring the change in the state of polarisation of light reflected at a surface in the absence and presence of an adsorbed layer, the mean refractive index (n) and layer thickness (d) of the adsorbed layer can be obtained. This LPS concentration corresponds to saturation in the LPS adsorption isotherm under these conditions. ARTICLE of data collection and generated a large number of tr-NOE cross-peaks.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34802890066&p=1pl&v=1&x=3d-jvbsKa-ZTabLWHurVnw
10.1016/j.mito.2018.08.001,Medicine_easy_380,"Naviaux's team is preparing for a larger, longer trial in 2019.",Exercise increases physiologic reserve capacity and resilience to periodic exposure to stress or acute illness.,"But the benefits were transient, fading and disappearing as the drug exited their systems. Naviaux's team is preparing for a larger, longer trial in 2019. ""It's abnormalities in metabokine signaling that cause the normal stages of the cell danger response to persist abnormally, creating blocks in the healing cycle,"" said Navaiux, who noted CDR theory also explains why some people heal more quickly than others and why a chronic disease seemingly treated successfully can relapse.","In many important metabolic ways, exercise ""reminds"" the body how to heal and promotes disease-free health throughout life. Exercise increases physiologic reserve capacity and resilience to periodic exposure to stress or acute illness. Exercise combats this loss.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37052707703&p=1pl&v=1&x=sh4bblHfq4G8CThdM37YaA
10.1073/pnas.1704745114,Medicine_easy_382,"""Our work has important implications for understanding how crops and weeds grow,"" said study author George Bassel of the University of Birmingham.",These features are present in the less dormant model (Fig.,"This proved the scientists' theory that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, rather than constant environments and temperatures. ""Our work has important implications for understanding how crops and weeds grow,"" said study author George Bassel of the University of Birmingham. The knowledge gained in the study can be applied to commercial plants and crops to control germination, which may increase crop yields and potentially eliminate the need for herbicides.","3 ), and these effects increase with the progressive loss of the depth of dormancy . These features are present in the less dormant model (Fig. 1C) and not the highly dormant model (Fig.",[1],Medicine,train,1.0,news,http://www.natureworldnews.com/articles/38372/20170609/scientists-germinate-brain-plant-crops.htm
10.1073/pnas.1403984111,Medicine_easy_383,"""It also highlights the importance of the accurate collection of data as part of their day-to-day patrol work, which is essential to understand and communicate the true proportions of the threat that elephants face.""",Annual illegal killing of elephants in the Samburu population during 2009 to 2012 exceeded those of all previous years of monitoring (1998) (1999) (2000) (2001) (2002) (2003) (2004) (2005) (2006) (2007) (2008) with an estimated aggregate of 20.8% of the known elephants illegally killed during that 4-y period.,"Such figures cause conservationists alarm, as the study shows over 54 percent is a level of poaching that elephant birth rates are unable to overcome and will lead to population decline. ""It also highlights the importance of the accurate collection of data as part of their day-to-day patrol work, which is essential to understand and communicate the true proportions of the threat that elephants face."" Both came to similar conclusions.","The population was subjected to unsustainable rates of illegal killing between 2009 and 2012, escalating from a mean of 0.6% (SD = 0.4%) between 1998 and 2008 to a high of 8% in 2011 ( Fig. Annual illegal killing of elephants in the Samburu population during 2009 to 2012 exceeded those of all previous years of monitoring (1998) (1999) (2000) (2001) (2002) (2003) (2004) (2005) (2006) (2007) (2008) with an estimated aggregate of 20.8% of the known elephants illegally killed during that 4-y period. Preliminary numbers from 2013 indicated the annual rate of illegal offtake remained concerning at around 3.7%, although below the peak levels experienced in 2011.",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/colorado-state-university-study-verifies-more-than-100-000-african-elephants-killed-in-three-years
10.1073/pnas.1408439111,Medicine_easy_384,"During the holiday season, populations in cities dropped sharply, while tourist sites such as coastlines and Disneyland Paris boomed.","This ability allows us to follow how population distribution changes through time in relation to the week, the season, or any particular event affecting populations over large spatial extents.","The results showed clear trends in population dynamics across weeks and seasons that traditional survey-based censuses can't reflect, the team reports online today in Proceedings of the National Academy of Sciences. During the holiday season, populations in cities dropped sharply, while tourist sites such as coastlines and Disneyland Paris boomed. They found that the two methods are comparable in accuracy when checked against actual survey-based census data, but estimates from mobile phone data can provide more timely information, down to the hours.","In countries where detailed human population census data are available at high resolution, the main value added is not so much in the gain in spatial resolution, but more in the ability to estimate population numbers and densities at high spatial resolution for any time period. This ability allows us to follow how population distribution changes through time in relation to the week, the season, or any particular event affecting populations over large spatial extents. The relevance of the MP approach is even greater in low-income countries where population distribution data may be scarce, outdated, and unreliable.",[1],Medicine,train,1.0,news,http://news.sciencemag.org/math/2014/10/taking-census-cellphones
10.1534/genetics.116.197285,Medicine_easy_385,"/ no comments





LAWRENCE -- Rest easy, folks.",It is clear that there is a need for more detailed modeling of CGD on several fronts.,"/ no comments





LAWRENCE -- Rest easy, folks. So natural selection favors individuals lacking modified genes and purges a given genetic alteration within a population within a few generations. ""By doing that they spread through a population much more quickly.""","Note that our theory also allows the assessment of strategies involving the purposeful release of resistance alleles for controlling a drive. It is clear that there is a need for more detailed modeling of CGD on several fronts. Furthermore, resistance alleles may be created if homology-directed repair inserts the driver construct, but introduces errors that prevent it from driving.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1186/s40168-015-0071-z,Medicine_easy_386,So those women make much less of the special sugar.,Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).,"""Bifidobacteria sort of push other bacteria out. So those women make much less of the special sugar. And they were right.","Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ). Of 35 milks from non-secretors, 20 of the matched infant stool samples were Low-Bif qPCR (57.1%).",[1],Medicine,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1073/pnas.1403984111,Medicine_easy_387,He credits investments in fighting poachers and hopes that efforts to reduce demand in China for ivory are starting to help.,"More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year.","The rate of poaching across Africa seems to have declined to about 5% last year, which is still unsustainable for the population, Wittemyer says. He credits investments in fighting poachers and hopes that efforts to reduce demand in China for ivory are starting to help. ""It's not even close to being over.""","At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼8% in 2011 which extrapolates to ∼40,000 elephants illegally killed and a probable species reduction of ∼3% that year. Preliminary data from 2013 indicate overharvesting continued.",[1],Medicine,train,1.0,news,http://news.sciencemag.org/africa/2014/08/poaching-drives-overall-elephant-decline-africa
10.1007/s40279-014-0157-y,Medicine_easy_388,"Pull a 2-in-1

If your week is packed, you can run on a strength-training day, but it should be low in mileage, duration, and/or effort.",Future researchers should take this into consideration when assigning velocities for economy assessment.,"""Every good program should always have at least one complete day of rest, which will help you to avoid overdoing it,"" says Velasquez. Pull a 2-in-1

If your week is packed, you can run on a strength-training day, but it should be low in mileage, duration, and/or effort. And make sure to hit the weights before the road--doing so ensures you get the most out of your weight training and can maintain form.","Consequently, the most valid measurement of economy may be at specific race velocities and power outputs, rather than an arbitrary submaximal intensity which is commonly used. Future researchers should take this into consideration when assigning velocities for economy assessment. This combined neuromuscular and anaerobic ability may be the differentiating factor for elite endurance performance as successful athletes at world-level can produce high velocities and power outputs to win a race following a sustained period of highintensity exercise (i.e.",[1],Medicine,train,1.0,news,http://www.womenshealthmag.com/fitness/cardio-and-strength-training
10.1088/1741-2552/aabc9b,Medicine_easy_389,"The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods.","This approach is helpful for rapid algorithm prototyping and visualization of signals in realtime before implementing fully embedded adaptive DBS, for which algorithm troubleshooting is more challenging.","Because adaptive deep brain stimulation did not continuously stimulate the brain, the system saved about 40 percent of the device's battery energy used during traditional stimulation. The short time periods over which movement was assessed did not permit comparison of the two deep brain stimulation paradigms relative to incidence of dyskinesia, but it is hoped that the variable stimulation will also translate into a reduction in adverse effects when tested over longer time periods. ""Instead, our device receives feedback from the motor cortex, far from the stimulation source, providing a more reliable signal.""","The stimulation delivered by the Activa SC was not altered during adaptive DBS. This approach is helpful for rapid algorithm prototyping and visualization of signals in realtime before implementing fully embedded adaptive DBS, for which algorithm troubleshooting is more challenging. The ""Nexus E"" interface allows for simple control algorithms, based on spectral power in pre-specified frequency bands, to be implemented within Activa PC+S .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34175486612&p=1pl&v=1&x=_1eTrGJQyGkkr4UeWUolqA
10.1080/10635150701775111,Medicine_easy_390,"Yet, Chih-Ming is confident.",Dorsal scales of foreand hind limbs weakly keeled.,"In all three cases, the data was limited, especially in the case of the ecological niche modeling. Yet, Chih-Ming is confident. All results were consistent.",Dorsolateral body scales much larger than dorsal scales. Dorsal scales of foreand hind limbs weakly keeled. Scales of lateral portion of body weakly keeled.,[1],Medicine,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1534/genetics.116.197285,Medicine_easy_391,It's like the perfect template for repairing your 2007 Honda Civic.,"(N e /N )⇡, and N thus simply cancels out in the products u µ (i)⇡(i).","""Obviously that doesn't work most of the time. It's like the perfect template for repairing your 2007 Honda Civic. But organisms use both NHEJ and homology-directed repair.","If the effective population size differs from the census size, this will not affect Equation (17), but will change the establishment probability of a new allele specified by Equation (8). (N e /N )⇡, and N thus simply cancels out in the products u µ (i)⇡(i). Resistance alleles from de novo mutations can only arise as long as the driver has not yet fixed in the population.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1038/s41467-018-06824-8,Medicine_easy_392,"""It seemed a good place to start.""",Analyses of syx1a expression levels relative to the second housekeeping gene GAPDH generated the same statistical outcomes.,"The gene, linked to social behavior in a number of animals, was the one that best differentiated social from solitary sweat bees, Kocher says. ""It seemed a good place to start."" The social bees' gene was about 15 times as active as that of the solitary bees, her team reports today in Nature Communications , making it a strong candidate for the switch to sociality.","4) . We elected to focus our functional analyses on two of these SNPs because: (1) they showed the highest estimates of divergence (of the seven SNPs in syx1a) between all social and all solitary populations, and (2) these two SNPs were in strong LD with each other (Supplementary Fig. Analyses of syx1a expression levels relative to the second housekeeping gene GAPDH generated the same statistical outcomes.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37425745606&p=1pl&v=1&x=BF9poLDtNwHfjOufQy7mMA
10.1534/genetics.116.197285,Medicine_easy_393,"""Obviously that doesn't work most of the time.","Generally, as long as resistance alleles do not carry large costs themselves and provide any fitness advantage over the driver, evolution of resistance from the SGV is practically assured whenever θ > 0.1, whereas it remains unlikely for θ << 0.1 (Fig.","We argue resistance could be thought of as a good thing -- if we know it's going to evolve, we can plan around it, and understand a gene drive is a temporary solution. ""Obviously that doesn't work most of the time. It's like the perfect template for repairing your 2007 Honda Civic.","Similarly, lower driver costs decrease π(t) and thus P SGV , as resistance alleles will have a smaller fitness advantage (SI Fig. Generally, as long as resistance alleles do not carry large costs themselves and provide any fitness advantage over the driver, evolution of resistance from the SGV is practically assured whenever θ > 0.1, whereas it remains unlikely for θ << 0.1 (Fig. 2 ), consistent with general results for the probability of adaptation from SGV after an environmental shift [17] .",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1098/rsos.171474,Medicine_easy_394,"It will still be available this weekend on ESPN's digital channels, including its app.",One noteworthy attempt to bring a measure of harmony to the existing literature is that by Hilgard et al.,"The decision comes in the wake of the two shootings that prompted politicians, including President Donald Trump, to say video games that glorify violence could be contributing to the country's shooting epidemic. It will still be available this weekend on ESPN's digital channels, including its app. ""Blaming video games is a 'look over there' move instead of a 'look at ourselves' reflection.","This interpretation is not uniform; other analyses of the literature conducted by Sherry and Ferguson provide evidence the GAM framing, and the idea that games cause aggression more broadly, is incomplete, not evidenced or flawed. One noteworthy attempt to bring a measure of harmony to the existing literature is that by Hilgard et al. Their analysis detected the presence of publication bias not uncovered in the original reporting of the data.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39907846044&p=1pl&v=1&x=qR_l8J7Kj5CPAEm_xm1uww
10.1007/s40279-014-0157-y,Medicine_easy_395,"Pencil it in

Trying to pack all of this into one week may feel overwhelming--it definitely did to me at first, too!",found no difference in w _ VO 2max during a cycling protocol.,"In fact, running can actually decrease mobility in certain joints, since the repetitive motion doesn't allow hips and ankles to go through their full ranges of motion. Pencil it in

Trying to pack all of this into one week may feel overwhelming--it definitely did to me at first, too! It's a bit neurotic, but it helps... and now I'm never double-booking during my workout time.","established a significant increase in peak treadmill velocity at _ VO 2max (p \ 0.01; ES = 0.55), whereas Hausswirth et al. found no difference in w _ VO 2max during a cycling protocol. argue that the aerobic system is still strongly involved during a _ VO 2max test, and v _ VO 2max = w _ VO 2max should not be used as a pure measure of endurance-specific muscle power performance.",[1],Medicine,train,1.0,news,http://www.womenshealthmag.com/fitness/cardio-and-strength-training
10.1038/s41598-018-26198-7,Medicine_easy_396,"""Finding changes in both markers of the immune system ramping up its attack on cancer cells as well as markers of inflammation resolution suggests a potentially important link between these two areas of inquiry,"" Dr. Langevin adds.","While our method of stretching does not fully suspend the animal, since its front feet are allowed to grip a bar of the cage, some stress inevitably results from being restrained by the tail, and muscle activity is required to maintain the stretched posture; in the no stretch group, we did not hold the mice by the tail, as they have a tendency to pull away which can cause inadvertent stretching of tissues.","They highlight the ""interesting possibility"" that stretching could effectively keep inflammation under control, without suppressing the natural cytotoxic immune response against the cancer cells, and then rescuing the cytotoxic function of exhausted T cells. ""Finding changes in both markers of the immune system ramping up its attack on cancer cells as well as markers of inflammation resolution suggests a potentially important link between these two areas of inquiry,"" Dr. Langevin adds. The authors do acknowledge that the active stretching model in mice is complex, and factors such as mild stress may also be relevant.","One key consideration is that, like exercise, our active stretching model is a complex intervention. While our method of stretching does not fully suspend the animal, since its front feet are allowed to grip a bar of the cage, some stress inevitably results from being restrained by the tail, and muscle activity is required to maintain the stretched posture; in the no stretch group, we did not hold the mice by the tail, as they have a tendency to pull away which can cause inadvertent stretching of tissues. Both active and passive stretching had similar effects compared with anesthesia alone, and there was no significant difference between the effects of active and passive stretching 23 .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34125675804&p=1pl&v=1&x=EIuTbzUDbEKkr7kvXb-kdg
10.1007/s13187-013-0592-8,Medicine_easy_397,"Black survivors also are more likely to receive ""inadequate post-treatment surveillance"" for cancer recurrence, the report says.","Then, I just started to cry because I just knew.""","For most cancers, the five-year relative survival rate is lower for black patients than white patients - even after controlling for the stage of a patient's cancer at diagnosis - and much of that disparity appears tied to differences in health insurance coverage, the report notes. Black survivors also are more likely to receive ""inadequate post-treatment surveillance"" for cancer recurrence, the report says. Racial and ethnic minorities also tend to be underrepresented in large clinical trials - ""a major barrier to health equity in cancer treatment,"" according to the study.","Most survivors did not identify their cancer through conscious preventive measures, but through randomly identifying ""a lump"" and then conducting a self-breast exam and going to their doctor for diagnostic screening. Then, I just started to cry because I just knew."" In retrospect, many women offered advice to encourage African-American women to get screening.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39437519490&p=1pl&v=1&x=hIawzcsvTMkDXewMLvf5FQ
10.2337/dc12-2084,Medicine_easy_399,"""This also opens the door for a new approach that could really benefit the lives of these children.""",Our study suggests that long-chain omega-3 fatty acids may provide protection to the b-cell after clinical diagnosis of type 1 diabetes.,"Diet additions may help youth with Type 1 diabetes keep producing own insulin

Adding foods rich in specific amino and fatty acids to the diets of youth with Type 1 diabetes kept them producing some of their own insulin for up to two years after diagnosis, said researchers at the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill."" ""This also opens the door for a new approach that could really benefit the lives of these children."" Mayer-Davis noted the study reflects subjects eating actual foods rich in these nutrients, not taking supplements.","However, significantly reduced risk of development of islet autoimmunity was associated with increased intake of omega-3 fatty acids among youth genetically susceptible to development of type 1 diabetes (36), although continued follow-up did not reveal subsequent protection against incident type 1 diabetes (37). Our study suggests that long-chain omega-3 fatty acids may provide protection to the b-cell after clinical diagnosis of type 1 diabetes. Our results support further study of the potential role of branched-chain amino acids to enhance sustained insulin production in type 1 diabetes.",[1],Medicine,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/40953-diet-additions-may-help-youth-with-type-1-diabetes-keep-producing-own-insulin.html
10.1001/jamaophthalmol.2017.4816,Medicine_easy_402,"Even in appointments for which the trainee was not present, the presence of a trainee in a clinic session was correlated with longer mean appointment time (mean, 87.2 versus 80.3 minutes).","The presence of a trainee in a clinic session was associated with longer mean appointment times, even in appointments in which the trainee was not present.","The researchers found that appointments with trainees were significantly longer than appointments in clinic sessions without trainees (mean, 105 versus 80.3 minutes). Even in appointments for which the trainee was not present, the presence of a trainee in a clinic session was correlated with longer mean appointment time (mean, 87.2 versus 80.3 minutes). Among the 33 study physicians, three, one, and 29 had shorter, no change in, and longer mean appointment times when a trainee was present.","Findings In this single-center cohort study of 49 448 outpatient ophthalmology appointments by 33 attending physicians, appointments with residents and fellows were 32% and 30% longer, respectively, than appointments without trainees. The presence of a trainee in a clinic session was associated with longer mean appointment times, even in appointments in which the trainee was not present. Meaning Academic medical centers face potential challenges in maintaining clinical efficiency and medical education, particularly in emerging value-based reimbursement models.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=32519400937&p=1pl&v=1&x=h8CIkB_TZAebA9x0rdJEgQ
10.1001/jamaoncol.2017.5667,Medicine_easy_404,"With the MRI model, 18 of 100 fewer biopsies could have been performed, with no increase in missed clinically significant prostate cancers.","Eighteen of 100 fewer biopsies could have been performed, with no increase in the number of patients with missed clinically significant prostate cancers.","The MRI model had a lower false-positive rate than the baseline model at a risk threshold of 20 percent (46 [95 percent confidence interval, 32 to 66 percent] versus 92 percent [95 percent confidence interval, 70 to 100 percent]), with a small reduction in the true-positive rate (89 [95 percent confidence interval, 85 to 96 percent] versus 99 percent [95 percent confidence interval, 89 to 100 percent]). With the MRI model, 18 of 100 fewer biopsies could have been performed, with no increase in missed clinically significant prostate cancers. ""The inclusion of MRI-derived parameters in a risk model could reduce the number of unnecessary biopsies while maintaining a high rate of diagnosis of clinically significant prostate cancers,"" the authors write.","At a risk threshold of 20%, the MRI model had a lower false-positive rate than the baseline model (46% [95% CI, 32%-66%] vs 92% [95% CI, 70%-100%]), with only a small reduction in the true-positive rate (89% [95% CI, 85%-96%] vs 99% [95% CI, 89%-100%]). Eighteen of 100 fewer biopsies could have been performed, with no increase in the number of patients with missed clinically significant prostate cancers. Data acquisition and reporting were consistent with the Standards of Reporting for MRI-targeted Biopsy Studies (START) of the recommendations for the prostate.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33409750483&p=1pl&v=1&x=Eq3brMqNx1jvME6Zq_cliw
10.1007/s00125-015-3781-7,Medicine_easy_405,"During the period 1996-2011, a total of 2,832 amputations were performed of which 1,285 were among patients with diabetes and 1,547 among individuals without diabetes.","The total number of amputations amounted to 2,832, of which 1,285 were among individuals with diabetes and 1,547 among individuals without diabetes.","Despite the reductions in amputation rates for people with diabetes, they remained far more likely to have an amputation than those without diabetes. During the period 1996-2011, a total of 2,832 amputations were performed of which 1,285 were among patients with diabetes and 1,547 among individuals without diabetes. Diabetes patients had an 11-times increased rate of BAA relative to persons without diabetes.","The different curves thus start at age of diagnosis and duration of diabetes equal to 0, so it can be seen that the initial high rates decrease in about 1 year and the major effect is then age related. The total number of amputations amounted to 2,832, of which 1,285 were among individuals with diabetes and 1,547 among individuals without diabetes. We found a substantial reduction by calendar time in BAA rates among patients with diabetes of almost 10% per year.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/major-fall-in-diabetes-related-amputations-since-the-1990s/
10.1186/s12940-018-0421-y,Medicine_easy_406,"Dow Chemical study produced 'misleading' results

We further found issues which inappropriately decrease the ability of the studies to reveal true effects, including a dosage regimen that resulted in too low exposure of the nursing pups for chlorpyrifos and possibly for chlorpyrifos-methyl, and a failure to detect any neurobehavioral effects of lead nitrate used as positive control in the chlorpyrifos study.","We further found issues which inappropriately decrease the ability of the studies to reveal true effects, including a dosage regimen that resulted in too low exposure of the nursing pups for chlorpyrifos and possibly for chlorpyrifos-methyl, and a failure to detect any neurobehavioral effects of lead nitrate used as positive control in the chlorpyrifos study.","Dow Chemical study produced 'misleading' results

We further found issues which inappropriately decrease the ability of the studies to reveal true effects, including a dosage regimen that resulted in too low exposure of the nursing pups for chlorpyrifos and possibly for chlorpyrifos-methyl, and a failure to detect any neurobehavioral effects of lead nitrate used as positive control in the chlorpyrifos study. Our observations thus suggest that conclusions in test reports submitted by the producer may be misleading. This discrepancy affects the ability of regulatory authorities to perform a valid and safe evaluation of these pesticides.","We noted treatment-related changes in a brain dimension measure for chlorpyrifos at all dose levels tested, although not been reported in the original test summary. We further found issues which inappropriately decrease the ability of the studies to reveal true effects, including a dosage regimen that resulted in too low exposure of the nursing pups for chlorpyrifos and possibly for chlorpyrifos-methyl, and a failure to detect any neurobehavioral effects of lead nitrate used as positive control in the chlorpyrifos study. Our observations thus suggest that conclusions in test reports submitted by the producer may be misleading.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37923386732&p=1pl&v=1&x=tmRJDzIyel0iLSnuaiuv0A
10.1186/s10194-018-0916-5,Medicine_easy_407,"""Migraineurs with insomnia experienced a higher headache intensity and impact of headache ... compared to migraineurs without insomnia.",Migraineurs with insomnia experienced a higher headache intensity and impact of headache (HIT-6 score) compared to migraineurs without insomnia (Table 3) .,"""These findings suggest that the headache status does not influence the overall severity of insomnia among affected individuals. In contrast, insomnia has a significant impact on the clinical presentation of migraine,"" the authors stated. ""Migraineurs with insomnia experienced a higher headache intensity and impact of headache ... compared to migraineurs without insomnia.","In contrast, insomnia has a significant impact on the clinical presentation of migraine. Migraineurs with insomnia experienced a higher headache intensity and impact of headache (HIT-6 score) compared to migraineurs without insomnia (Table 3) . It is possible that their distinct anatomy and pathophysiology contribute to the contrast findings.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37508029023&p=1pl&v=1&x=NpyIs2Y_TfCnoQt5fi_dUg
10.1038/s41591-018-0013-y,Medicine_easy_408,The collaborating teams in Switzerland and Spain claim their findings suggest that in a particular genetic background PM20D1 contributes to neuroprotection against AD.,"These findings suggest that in a particular genetic background, PM20D1 contributes to neuroprotection against AD.","Genetically boosting PM20D1 expression in AD mice reduced AD-related pathologies, whereas genetically depleting PM20D1 promoted disease progression. The collaborating teams in Switzerland and Spain claim their findings suggest that in a particular genetic background PM20D1 contributes to neuroprotection against AD. ""This variation is associated with the loss of activity of a neuroprotective gene called PM20D1; whoever possesses the variation has a greater probability of suffering from AD, so people carrying these variants could be excellent candidates for clinical prevention trials of the disease in the future,"" comments co-researcher Manel Esteller, M.D., Ph.D., director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher, and professor of genetics of the University of Barcelona.","In line, genetically increasing or decreasing the expression of PM20D1 reduces and aggravates AD-related pathologies, respectively. These findings suggest that in a particular genetic background, PM20D1 contributes to neuroprotection against AD. When we re-analyzed these biologically and technically independent datasets by focusing exclusively on the comparison between samples from healthy controls and patients with advanced-stage AD, we noted that only one gene, PM20D1, which was previously described as a mQTL , consistently displayed promoter hypermethylation in patients with AD (hereafter referred to as AD samples) than in healthy controls in both studies (Fig.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34070583365&p=1pl&v=1&x=qsJQCFeEwdzOAnJYU5yj9g
10.1038/s41598-019-41135-y,Medicine_easy_409,"""We have looked at 14 species and among eight open-water and shoreline foraging species that have undergone significant population declines, five were negatively associated with temperature increases,"" Safeeq said in an email interview.","Finally, among eight open-water and shoreline foraging species that have undergone significant populations declines, five were negatively associated with temperature increases ( Fig.","If they don't find water at their breeding sites, specifically fresh water, they won't be able to survive. ""We have looked at 14 species and among eight open-water and shoreline foraging species that have undergone significant population declines, five were negatively associated with temperature increases,"" Safeeq said in an email interview. The report also found that drier summers lead to saltier wetlands, and that's a major problem for birds that are unaccustomed to a saline environment.","In addition, associations between long-term and large-scale trends in climate and hydrology for waterbird assemblages were evident from a non-metric multidimensional scaling analysis (nMDS; see methods section; Fig. Finally, among eight open-water and shoreline foraging species that have undergone significant populations declines, five were negatively associated with temperature increases ( Fig. Here, we provide evidence that recent climate change is affecting an entire landscape of terrestrial and wetland ecosystems in a complex manner: climate-induced shifts in water volume drive changes in wetland salinity, which determines wetland community composition, which in turn determines waterbird use of the region.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38788883587&p=1pl&v=1&x=cTbex_LwQXrrjx9pS0d6RQ
10.1192/bjp.bp.111.101196,Medicine_easy_410,"Given the and impact of the ADHD, one might have expected that older adults with ADHD would experience impairments in these three areas.""",Given the chronicity and impact of the ADHD one might have expected that older adults with ADHD experience impairments in these three areas.,"But they add, ""Another striking finding is that older adults with ADHD did not differ in living situation, level of education, and income compared with older adults without ADHD. Given the and impact of the ADHD, one might have expected that older adults with ADHD would experience impairments in these three areas."" However, the respondents themselves did report that their ADHD had a negative impact on many areas of functioning, currently and in childhood.","Another striking finding is that older adults with ADHD did not differ in living situation, level of education and income compared to older adults without ADHD. Given the chronicity and impact of the ADHD one might have expected that older adults with ADHD experience impairments in these three areas. There are several explanations for this finding.",[5],Medicine,train,5.0,news,http://psychcentral.com/news/2014/04/15/attention-deficit-symptoms-in-older-people/68528.html
10.1001/jama.2013.276302,Medicine_easy_411,"""Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, may be important,"" the study states.","Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, 15,32,33 may be important.","Though these results are encouraging, showing ACOs can have a major effect on healthcare costs and further systemic change, they also present a ""free-riding"" problem. Since insurers can reap the benefits of an ACO without having value-based contracts themselves, they may be less likely to pursue the model on their own. ""Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, may be important,"" the study states.","Conversely, cost-reducing spillovers present a free-riding problem to commercial insurers engaged in ACO contracts, since competing insurers with similar provider networks could offer lower premiums without incurring the costs of managing an ACO. Additional efforts to foster multipayer participation in global payment systems, such as recent state initiatives and provisions in Pioneer Medicare ACO contracts, 15,32,33 may be important. Our study had several limitations.",[5],Medicine,train,5.0,news,http://www.beckershospitalreview.com/accountable-care-organizations/commercial-acos-produce-medicare-savings-study-finds.html
10.1038/s41390-018-0199-1,Medicine_easy_412,"""We suggest that the prevention of weight problems in women of childbearing age may benefit their later offspring and could reduce the burden of regulatory problems in infancy and prevent their long-term neurodevelopmental consequences,"" Girchenko said.",Our findings suggest that prevention of overweight/obesity in women of childbearing age will benefit the offspring by reducing the burden of regulatory problems in infancy and preventing their long-term neurodevelopmental consequences.,"The research team confirmed that weight was the primary factor, and not whether the mom had high blood pressure or gestational diabetes. In conclusion, the findings reveal that regulatory problems in infancy may have prenatal origins that can be attributed at least partially to mothers being overweight or obese, said lead author Polina Girchenko, a doctoral student of the University of Helsinki. ""We suggest that the prevention of weight problems in women of childbearing age may benefit their later offspring and could reduce the burden of regulatory problems in infancy and prevent their long-term neurodevelopmental consequences,"" Girchenko said.","In sum, our study showed that infants of overweight/obese mothers displayed higher levels of regulatory behavior problems and were more likely to display problems on multiple areas of behavioral self-regulation. Regulatory behavior problems partially mediated the effects of maternal overweight/obesity on childhood developmental milestones. Our findings suggest that prevention of overweight/obesity in women of childbearing age will benefit the offspring by reducing the burden of regulatory problems in infancy and preventing their long-term neurodevelopmental consequences.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37410791006&p=1pl&v=1&x=kBMJpUsrpIL-rs9R4JEiCg
10.1001/jamapediatrics.2013.78,Medicine_easy_414,The study also found that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not.,"This study builds on recent research focusing on fathers and their role in adolescent eating disorders treatment 32, [41] [42] [43] and finds that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not.","The results also indicate that weight conversations from one parent or from both parents were associated with a significantly higher prevalence of dieting relative to parents who engaged in only healthful eating conversations (35.2 percent and 37.1 percent vs. 21.2 percent, respectively). The study also found that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not. ""Finally, for parents who may wonder whether talking with their adolescent child about eating habits and weight is useful or detrimental, results from this study indicate that they may want to focus on discussing and promoting healthful eating behaviors rather than discussing weight and size, regardless of whether their child is nonoverweight or overweight,"" the authors conclude.","This approach may be particularly important for parents of overweight or obese adolescents. This study builds on recent research focusing on fathers and their role in adolescent eating disorders treatment 32, [41] [42] [43] and finds that adolescents whose fathers engaged in weight conversations were significantly more likely to engage in dieting and UWCBs than adolescents whose fathers did not. Thus, it may be important to educate fathers to avoid any form of weight-related conversations with their adolescents.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/06/130624172806.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jama.2014.15704,Medicine_easy_415,"The date of last patient follow-up was May 25, 2013.","The date of last patient follow-up was May 25, 20.","This HBV reactivation risk exists for patients with lymphoma treated with chemotherapies containing the drug rituximab. The date of last patient follow-up was May 25, 2013. The researchers found that the rates were significantly lower for the entecavir group vs the lamivudine group for hepatitis (8.2 percent vs 23.3 percent), HBV-related hepatitis (0 percent vs 13.3 percent), HBV reactivation (6.6 percent vs 30 percent), delayed hepatitis B (0 percent vs 8.3 percent), and chemotherapy disruption (1.6 percent vs 18.3 percent).","The date of last patient follow-up was May 25, 20. Incidence of HBV-related hepatitis was significantly lower for the entecavir group vs the lamivudine group. Due to the increasing incidence of diffuse large B-cell lymphoma and extensive use of the R-CHOP regimen, the risk for HBV reactivation has greatly increased.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/12/141216161445.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jama.2014.2850,Medicine_easy_416,The authors note that the effects found in this study have to be weighed against costs of the STEMO concept.,These effects have to be weighed against costs of the STEMO concept.,"STEMO deployment was not associated with increased risk for intracerebral hemorrhage or 7-day mortality. The authors note that the effects found in this study have to be weighed against costs of the STEMO concept. Depending on the configuration of the vehicle, a single STEMO ambulance costs about $1.4 million.","Nevertheless, even the 15-minute time reduction detected in the catchment area has been associated with better outcomes in larger cohorts. These effects have to be weighed against costs of the STEMO concept. Depending on the configuration of the vehicle, a single STEMO ambulance costs about €1 million (US$1.4 million).",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/04/140422162305.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1317920111,Medicine_easy_417,Javey notes that the use of elastic fibers with a small spring constant as the structural component of the whiskers provides large deflection and therefore high strain in response to the smallest applied pressures.,"Notably, the use of high-aspect-ratio elastic fibers with small spring constant (see Supporting Information for details) as the structural component of the whiskers provides large deflection and therefore high strain for smallest applied pressures.","""The composite can then be painted or printed onto high-aspect-ratio elastic fibers to form e-whiskers that can be integrated with different user-interactive systems."" Javey notes that the use of elastic fibers with a small spring constant as the structural component of the whiskers provides large deflection and therefore high strain in response to the smallest applied pressures. As proof-of-concept, he and his research group successfully used their e-whiskers to demonstrate highly accurate 2D and 3D mapping of wind flow.","The composite can be readily painted or printed on high-aspectratio elastic fibers to form e-whiskers, and eventually be integrated with different user-interactive systems. Notably, the use of high-aspect-ratio elastic fibers with small spring constant (see Supporting Information for details) as the structural component of the whiskers provides large deflection and therefore high strain for smallest applied pressures. The resistivity of the composite films is highly sensitive to mechanical strain and can be readily tuned by changing the composition ratio of the components.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/01/140121191452.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1136/bmjopen-2013-002893,Medicine_easy_418,"""Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long term health of our children,"" they conclude.",Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long-term health of our children.,"""The results of our study provide a useful baseline and strongly suggest that contemporary UK children are insufficiently active, implying that effort is needed to boost [physical activity] among young people to the level appropriate for good health,"" they write. This is likely to require population wide interventions, they say, including policies to make it easier for kids to walk to school, in a bid to increase physical activity and curb the amount of time they are sedentary. ""Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long term health of our children,"" they conclude.",There are many opportunities to increase PA through sport but also in other areas. The full potential to boost PA will only be realised with a comprehensive policy response that increases time spent in more intense PA and decreases the time spent being sedentary. Investing in this area is a vital component to deliver the Olympic legacy and improve the short and long-term health of our children.,[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/08/130822090511.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13756-019-0493-7,Medicine_easy_419,"The impact of specialty level culture, and peer influence appears to be important factors of antibiotic prescribing.","The impact of specialty level culture, and peer influence appears to be significant factors of antibiotic decision-making.","Hospitals were significantly (83% in teaching hospitals, 79% in regional hospitals, p = < 0.01) more likely to have antibiotic policies, when compared to primary care. A surveillance mechanism for antibiotic consumption was reported in 58% (104/178) of teaching hospitals and 62% (98/159) of regional hospitals. The impact of specialty level culture, and peer influence appears to be important factors of antibiotic prescribing.","This study with participants representing 53 countries provides insights into the main components of antibiotic stewardship programmes in different countries and the key factors which influence the antibiotic decision-making of key healthcare professionals. The impact of specialty level culture, and peer influence appears to be significant factors of antibiotic decision-making. These data identify existing gaps in adequate training and education for staff involved in stewardship, and the need for greater participation of nurses and pharmacists to ensure effective and sustainable stewardship programmes.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38590609963&p=1pl&v=1&x=WFWbZ39ALBU43TNOXZBu6g
10.1136/injuryprev-2014-041483,Medicine_easy_421,"""Future efforts should examine whether this association pertains at lower doses.""",Future efforts should examine whether this association pertains at lower doses.,"""SSRIs appear to increase fracture risk among middle-aged women without psychiatric disorders, an effect sustained over time, suggesting that shorter duration of treatment may decrease this,"" says Professor Matthew Miller, study lead author and part of the British Medical Journal group. ""Future efforts should examine whether this association pertains at lower doses."" The researchers emphasized that their research was conducted using only statistical data as a research tool therefore, other factors such as cause and effect links cannot be determined in this study.","Conclusions SSRIs appear to increase fracture risk among middle-aged women without psychiatric disorders, an effect sustained over time, suggesting that shorter duration of treatment may decrease fracture risk. Future efforts should examine whether this association pertains at lower doses. For example, escitalopram improves VMS as well as sleep disturbance related to the perimenopausal condition and improves quality of life.",[5],Medicine,train,5.0,news,http://www.techtimes.com/articles/64466/20150629/antidepressants-for-menopausal-women-ups-risk-of-bone-fractures-what-to-know.htm
10.1001/jamapediatrics.2013.455,Medicine_easy_422,"""Longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed),"" according to the study results.","RESULTS Adjusting for sociodemographics, maternal intelligence, and home environment in linear regression, longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed).","""Longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed),"" according to the study results. However, the study also noted that breastfeeding duration was not associated with Wide Range Assessment of Memory and Learning scores. As for fish intake (less than 2 servings per week vs. greater than or equal to 2 servings), the relationship between breastfeeding duration and the Wide Range Assessment of Visual Motor Abilities at 3 years of age appeared to be stronger in children of women with higher vs. lower fish intake, although this finding was not statistically significant, the results also indicate.","MAIN EXPOSURE Duration of any breastfeeding to age 12 months. RESULTS Adjusting for sociodemographics, maternal intelligence, and home environment in linear regression, longer breastfeeding duration was associated with higher Peabody Picture Vocabulary Test score at age 3 years (0.21; 95% CI, 0.03-0.38 points per month breastfed) and with higher intelligence on the Kaufman Brief Intelligence Test at age 7 years (0.35; 0.16-0.53 verbal points per month breastfed; and 0.29; 0.05-0.54 nonverbal points per month breastfed). Breastfeeding duration was not associated with Wide Range Assessment of Memory and Learning scores.",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2013/07/130729231601.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.drugalcdep.2013.12.012,Medicine_easy_423,"""The new DSM-5-AUD criteria has the advantage of shedding light on risky drinkers allowing for preventive and brief interventions, which could reach a large number of individuals.","DSM-5-AUD has the advantage of shedding light on risky drinkers included in the ""use in larger amounts class"", allowing for preventive interventions, which will reach a large number of individuals.","No link was found between gender and the two problematic alcohol classes, and Dr. Martins suggests this may be a result of the recent trend of increased alcohol use among females in Brazil and worldwide. ""The new DSM-5-AUD criteria has the advantage of shedding light on risky drinkers allowing for preventive and brief interventions, which could reach a large number of individuals. Future studies may distinguish additional patterns among users as well,"" said Dr. Martins.","The two symptomatic classes clearly represented the dimensionality of the new proposed AUD criteria, and could be more specifically targeted by different prevention or treatment strategies. DSM-5-AUD has the advantage of shedding light on risky drinkers included in the ""use in larger amounts class"", allowing for preventive interventions, which will reach a large number of individuals. As reported by nearly a quarter of all current alcohol users , this totals 11 criteria .",[5],Medicine,train,5.0,news,http://www.healthcanal.com/mental-health-behavior/47145-study-shows-how-the-new-diagnostic-and-statistical-manual-of-mental-disorders-can-help-at-risk-drinkers.html
10.1089/trgh.2017.0044,Medicine_easy_424,"According to the report, ""[t]his case illustrates that, in some circumstances, modest but functional lactation can be induced in transgender women.""","This case illustrates that, in some circumstances, modest but functional lactation can be induced in transgender women.","The report documents the successful treatment that allowed a 30-year-old trans woman to breastfeed her child, the first ever documented instance of this being possible. According to the report, ""[t]his case illustrates that, in some circumstances, modest but functional lactation can be induced in transgender women."" After one month of being on the prescribed regimen, which had been used to increase lactation in cisgender women, the woman was able to ""express droplets of milk,"" according to the report.","After implementing a regimen of domperidone, estradiol, progesterone, and breast pumping, she was able to achieve sufficient breast milk volume to be the sole source of nourishment for her child for 6 weeks. This case illustrates that, in some circumstances, modest but functional lactation can be induced in transgender women. The patient's medical history was significant for gender incongruence for which she initiated a feminizing hormone regimen in 2011.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33307118545&p=1pl&v=1&x=CviXLVqLYDLnzmegYXw7BA
10.1001/archophthalmol.2009.303,Medicine_easy_425,"""As racial inequities in educational opportunities decreased, near-work exposure may have increased relatively more in black participants than in white participants.""","As racial inequities in educational opportunities decreased, near-work exposure may have increased relatively more in black participants than in white participants.","""Black participants surveyed in 1971 to 1972 may have had less access to educational opportunities than white participants and consequently experienced less exposure to near work (a risk factor for myopia),"" the authors wrote. ""As racial inequities in educational opportunities decreased, near-work exposure may have increased relatively more in black participants than in white participants."" The 2009 study is hardly the first to suggest that an increase in years of formal education and access to technology across society may account for higher myopia rates in recent years.","Black participants surveyed in 1971-1972 may have had less access to educational opportunities than white participants and consequently experienced less exposure to near work (a risk factor for myopia ). As racial inequities in educational opportunities decreased, near-work exposure may have increased relatively more in black participants than in white participants. [24] The higher 1999-2004 prevalence rates might be explained by an increased proportion of persons with 12 or more years of formal education.",[5],Medicine,train,5.0,news,http://www.theatlantic.com/health/archive/2014/05/nearsightedness-and-the-indoor-life/361169/
10.1186/s12940-019-0488-0,Medicine_easy_426,"More than ten percent of total pesticide use in the USA was from pesticide ingredients either banned, not approved or of unknown status in all three of the other nations.","More than 10% of total pesticide use in the USA in 2016 was from pesticide ingredients either banned, not approved or of unknown status in all three agricultural nations (Table 1 and Additional file 5:  Table S137 ).","Of the 1.2 billion pounds of pesticides used in US agriculture in 2016, approximately 322 million pounds were pesticides banned in the EU, 40 million pounds were pesticides banned in China and nearly 26 million pounds were pesticides banned in Brazil. More than ten percent of total pesticide use in the USA was from pesticide ingredients either banned, not approved or of unknown status in all three of the other nations. Donley found that of 508 pesticide active ingredients that have been used in agriculture in the USA since 1970, 134 have been cancelled.","Of the 1.2 billion pounds of pesticides used in USA agriculture in 2016, roughly 322 million pounds were of pesticides banned in the EU, 40 million were of pesticides banned in China and nearly 26 million were of pesticides banned in Brazil (Table 1 and Additional file  5: Tables S131-S133 ). More than 10% of total pesticide use in the USA in 2016 was from pesticide ingredients either banned, not approved or of unknown status in all three agricultural nations (Table 1 and Additional file 5:  Table S137 ). From 1992 to 2016, the trends in use of the 13 pesticides that are banned in at least two other places and used in the USA varied by pesticide (Fig.",[5],Medicine,train,5.0,news,https://www.sciencedaily.com/releases/2019/06/190606223504.htm
10.1186/s12889-017-4672-2,Medicine_easy_428,"Even though this is an observational study, our findings do not support the hypothesis of adverse effects on child's language, communication and motor skills due to the use of mobile phone during pregnancy.""","Our unique findings do not support the hypothesis of adverse effects on children's language, communication and motor skills due to maternal cell phone use during gestation.","These findings provide further evidence that exposure to radio frequency electromagnetic fields associated with maternal use of mobile phones during pregnancy is not linked to neurodevelopment in children. Even though this is an observational study, our findings do not support the hypothesis of adverse effects on child's language, communication and motor skills due to the use of mobile phone during pregnancy."" Professor Jan Alexander, senior author from the Norwegian Institute of Public Health, said: ""Our investigation revealed for the first time that maternal mobile phone use may actually have a positive impact.","These associations were confirmed by dose-response trends, even after excluding non-users. Our unique findings do not support the hypothesis of adverse effects on children's language, communication and motor skills due to maternal cell phone use during gestation. Nevertheless, in the Spanish study cell phone users had children who scored higher in the Bayley mental scale and in the Danish study there was a trend for lower risk for cognitive/language delay at 6 months [ .",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/mobile-phone-use-while-pregnant-not-linked-to-child-neurodevelopment-problems/
10.1001/jama.2015.7515,Medicine_easy_429,"They note that the absolute cardiovascular event risk of statin-noneligible adults is not much lower with the ACC/AHA guidelines (1 percent) compared with the ATP III guidelines (2.4 percent), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3 percent vs 6.9 percent).","Although our analyses suggest that adherence to new ACC/AHA statin eligibility guidelines may prove beneficial for the reduction of future cardiovascular events compared with using the ATP III guidelines, the absolute event risk of statinnoneligible adults is not much lower with the ACC/AHA guidelines (1.0%) compared with the ATP III guidelines (2.4%), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3% vs 6.9%).","The authors write that extrapolating their findings to the approximately 10 million U.S. adults who are newly eligible for statins, an estimated 41,000 to 63,000 incident CVD events would be prevented over a 10-year period by adopting the ACC/AHA guidelines. They note that the absolute cardiovascular event risk of statin-noneligible adults is not much lower with the ACC/AHA guidelines (1 percent) compared with the ATP III guidelines (2.4 percent), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3 percent vs 6.9 percent). The researchers add that a risk-benefit analysis considering costs and potential adverse effects of statins, especially in patients with prediabetes and in lower-risk patients, is needed to provide a complete assessment of the effects of the change in statin eligibility guidelines on the health care system.","21 Analogous to their finding that participants with 50% or greater coronary stenosis were more frequently assigned statin therapy with the ACC/AHA guidelines than the ATP III guidelines (90% vs 60%, respectively), we show that those with high-risk CAC scores (>300) are more frequently allocated statin therapy with the ACC/AHA guidelines compared with the ATP III guidelines (5% vs 34%, respectively), and the HR among those with CAC scores greater than 300 for being statin eligible vs noneligible with the ACC/AHA guidelines is considerably higher than with the ATP III guidelines (HRs, 11 vs 3.6, respectively). Although our analyses suggest that adherence to new ACC/AHA statin eligibility guidelines may prove beneficial for the reduction of future cardiovascular events compared with using the ATP III guidelines, the absolute event risk of statinnoneligible adults is not much lower with the ACC/AHA guidelines (1.0%) compared with the ATP III guidelines (2.4%), and the larger benefit may be that the ACC/AHA guidelines identify many more statin-eligible participants with a similarly high event rate as the ATP III guidelines (6.3% vs 6.9%). In addition, a risk-benefit analysis considering costs and potential adverse effects of statins, especially in patients with prediabetes and in lower-risk patients, is needed to provide a complete assessment of the effects of the change in statin eligibility guidelines on the health care system.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/accuracy-of-newer-cholesterol-guidelines-in-identifying-increased-risk-of-cvd-events/
10.1073/pnas.1605036113,Medicine_easy_430,"For ET, indirect effects were, on average, 65 per cent of the size of direct effects.","For ET, indirect effects were, on average, 65% of the size of direct effects.","The simulations suggested that the indirect effects of increased CO2 on net primary productivity (how much carbon dioxide vegetation takes in during photosynthesis minus how much carbon dioxide the plants release during respiration) are large and variable, ranging from less than 10 per cent to more than 100 per cent of the size of direct effects. For ET, indirect effects were, on average, 65 per cent of the size of direct effects. Indirect effects tended to be considerably larger in water-limited ecosystems.","The simulations suggest that the indirect effects of elevated CO 2 on net primary productivity are large and variable, ranging from less than 10% to more than 100% of the size of direct effects. For ET, indirect effects were, on average, 65% of the size of direct effects. Indirect effects tended to be considerably larger in water-limited ecosystems.",[5],Medicine,train,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/c9qz2n8jSb0/
10.1016/j.amepre.2018.05.028,Medicine_easy_431,"The researchers identified genomic testing barriers including a lack of terminology understanding, health care system mistrust, reluctance to seek medical care, and unfavorable attitudes toward research.","Results: Identified genomic testing barriers included a lack of terminology understanding, healthcare system mistrust, reluctance to seek medical care, and unfavorable attitudes toward research.","Fifty-six participants were included in the study. The researchers identified genomic testing barriers including a lack of terminology understanding, health care system mistrust, reluctance to seek medical care, and unfavorable attitudes toward research. Barriers to research study participation included a lack of prostate cancer knowledge, prostate-specific antigen testing confusion, health care system distrust, and misuse of personal health information.","Because healthcare system mistrust has contributed to these disparities for centuries, black men may be less inclined to pursue novel testing, and identification of facilitators to their participation in prostate cancer research studies remains warranted. Results: Identified genomic testing barriers included a lack of terminology understanding, healthcare system mistrust, reluctance to seek medical care, and unfavorable attitudes toward research. Lack of prostate cancer knowledge, prostate-specific antigen testing confusion, healthcare system distrust, and misuse of personal health information were barriers to research study participation.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37556914670&p=1pl&v=1&x=a-8RKkdSAg5CxnyiRPJ2fQ
10.1016/j.amepre.2016.07.031,Medicine_easy_432,"There were 401 HIV-negative participants, of whom 168 (42 percent) were aware of PrEP.","Results: There were 401 HIV-negative participants, of whom 168 (42%) were aware of PrEP.","Side effects are generally mild. There were 401 HIV-negative participants, of whom 168 (42 percent) were aware of PrEP. Having seen a doctor (82 percent had) and having a test for another sexually transmitted disease (46 percent had) in the prior year did not increase the likelihood that a gay or bisexual man knew about PrEP.","Results: There were 401 HIV-negative participants, of whom 168 (42%) were aware of PrEP. Visiting a healthcare provider in the past 12 months, receiving an HIV test from a provider, and having a sexually transmitted infection test in the past 12 months were not significantly associated with PrEP awareness. PrEP awareness was associated with being out to a healthcare provider (OR¼2.97, 95% CI¼1.78, 4.96, po0.001); being tested for HIV (OR¼1.50, 95% CI¼1.06, 2.13, p¼0.023); and receiving condoms from an HIV/AIDS CBO (OR¼2.59, 95% CI¼1.43, 4.64, p¼0.001).",[5],Medicine,train,5.0,news,http://www.futurity.org/hiv-prep-gay-bisexual-men-1266322-2/
10.1377/hlthaff.2014.1428,Medicine_easy_433,"Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles.","Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles.","""Most effective"" states are those in the highest quartile of the exemption law effectiveness index; ""least effective"" states are those in the lowest quartile. Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles. (Credit: courtesy Health Affairs)

Vaccination exemption rates have increased drastically in the past 10 years, according to the study, due largely to religious and philosophical reasons, which fall under the nonmedical exemption category.","Another component associated with lower exemption rates was the ability to be exempt from text) . Thus, their scores on the index-which assesses the effectiveness of both nonmedical and medical exemption policies-would not be accurate, and they are not included in any of the four quartiles. This reduced exemption rates by 0.7 percent (Exhibit 3).",[5],Medicine,train,5.0,news,http://www.healthcanal.com/public-health-safety/65883-study-finds-state-policies-influence-vaccination-disease-outbreak-rates.html
10.1001/jamainternmed.2017.7720,Medicine_easy_434,"CVD risk did not differ with individual LABA agents, LAMA dosage forms, and concomitant COPD regimens.","Individual LABA agents, LAMA dosage forms, and concomitant COPD regimens did not differ in the CVD risks.","The researchers found that in patients with COPD, new LABA and LAMA use was associated with a 1.5- and 1.52-fold increased cardiovascular risk within 30 days of initiation, respectively; with prevalent use, the risk was absent or reduced. CVD risk did not differ with individual LABA agents, LAMA dosage forms, and concomitant COPD regimens. In an alternative case-crossover study the risk persisted, and it remained across subgroups without history of CVD or prior exacerbations.","New LABA and LAMA use in COPD was associated with a 1.50-fold (95% CI, 1.35-1.67; P < .001) and a 1.52-fold (95% CI, 1.28-1.80; P < .001) increased cardiovascular risk within 30 days of initiation, respectively, whereas the risk was absent, or even reduced with prevalent use. Individual LABA agents, LAMA dosage forms, and concomitant COPD regimens did not differ in the CVD risks. The risk persisted in an alternative case-crossover study and remained across subgroups without CVD history or prior exacerbations.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=32941222539&p=1pl&v=1&x=86oovtifFN21huIJ46h8cQ
10.1001/jama.2015.7120,Medicine_easy_435,"In 1 case, blood was sampled after completion of treatment for colorectal cancer and the abnormal pattern was no longer evident.","In 1 case, blood was sampled after completion of treatment for colorectal cancer and the abnormal pattern was no longer evident.","Maternal cancers most frequently occurred with the rare NIPT finding of more than 1 aneuploidy detected (7 known cancers among 39 cases of multiple aneuploidies by NIPT, 18 percent). In 1 case, blood was sampled after completion of treatment for colorectal cancer and the abnormal pattern was no longer evident. aEURoeHere we have shown that occult maternal malignancies may provide a biological explanation for some discordant NIPT results.","All 8 cases that underwent further bioinformatics analysis showed unique patterns of nonspecific copy-number gains and losses across multiple chromosomes. In 1 case, blood was sampled after completion of treatment for colorectal cancer and the abnormal pattern was no longer evident. CONCLUSIONS AND RELEVANCE In this preliminary study, a small number of cases of occult malignancy were subsequently diagnosed among pregnant women whose noninvasive prenatal testing results showed discordance with the fetal karyotype.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/certain-abnormal-prenatal-testing-results-and-subsequent-diagnosis-of-maternal-cancer/
10.1016/j.jneb.2017.10.010,Medicine_easy_436,"""The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research,"" she says.",The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research.,"Pesch says the U-M developmental and behavioral research team plans to further study what language and communication tactics are most effective in encouraging healthy eating among children. ""The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research,"" she says. ""Direct imperatives may in fact have a healthy, adaptive role in approaches to feeding to prevent childhood obesity, but we have to do more work to understand the nuances.""","In addition, mothers' behavior may have been influenced by knowledge that they were participating in a study about feeding behaviors. The finding that mothers of children with obesity used more direct imperatives to restrict eating may have important implications for practice guidelines and future research. Direct imperatives may have a healthy, adaptive role in approaches to feeding to prevent childhood obesity; they deserve careful consideration in future work.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/moms-of-obese-children-use-different-words-to-restrict-eating/
10.1001/jamaophthalmol.2017.4512,Medicine_easy_437,"""Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care,"" the authors write.","Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care.","The researchers found that cataract surgery was associated with a 60 percent reduced risk of death from all causes; and a 37 percent to 69 percent reduced risk of death due to pulmonary, accidental, infectious, neurologic and vascular diseases, and cancer. The study notes some limitations, including that because the WHI cohort is all female, findings from this study may not be generalizable to male patients. ""Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care,"" the authors write.","Further study of the interplay of cataract surgery, systemic disease, and disease-related mortality would be informative for improved patient care. 6 Furthermore, the WHI database contains information on total and cause-specific mortality, which is not available in other large databases of patients with cataract surgery in the United States. 7 These factors make the WHI an ideal cohort in which to examine the interplay between eye disease and a wide variety of systemic and lifestyle factors in US women.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/cataract-surgery-in-older-women-associated-with-decreased-risk-of-death/
10.1001/jamadermatol.2015.1568,Medicine_easy_438,"""Research regarding the motivations of indoor tanners could inform the development of new interventions,"" the study states.",5 Research regarding the motivations of indoor tanners could inform the development of new interventions.,"The overall downward trend of the rates is most likely due to increased awareness of these harms among the public along with government mandated regulation, according to researchers. ""Research regarding the motivations of indoor tanners could inform the development of new interventions,"" the study states. ""Physicians can also play a role through behavioral counseling, which is recommended for fair-skinned persons aged 10 to 24 years.","The Surgeon General has highlighted the importance of reducing the harms from indoor tanning and of continued public health efforts to identify and implement effective strategies to reduce indoor tanning. 5 Research regarding the motivations of indoor tanners could inform the development of new interventions. Physicians can also play a role through behavioral counseling, which is recommended for fairskinned persons aged 10 to 24 years.",[5],Medicine,train,5.0,news,http://www.medicaldaily.com/us-indoor-tanning-rates-have-dropped-among-adults-millions-still-do-it-despite-known-340886
10.1136/jech-2013-203159,Medicine_easy_440,"Policies focused only on adult health behaviours do not address the socially patterned causes of these behaviours, or the independent role played by these causes in social inequalities in health.""",▸ Policies focused only on adult health behaviours do not address the socially patterned causes of these behaviours or the independent role played by these causes in social inequalities in health.,"Our work provides evidence that social inequalities in health will persist unless prevention strategies tackle the intergenerational transmission of disadvantage and risk."" Policies focused only on adult health behaviours do not address the socially patterned causes of these behaviours, or the independent role played by these causes in social inequalities in health."" David Buck, Senior Fellow at health think-tank The Kings Fund, says: ""We welcome this study which demonstrates how important early life experiences are directly to our long-term health, and how this is reinforced through shaping our health behaviours which then track through to adulthood and early death.","What this study adds ▸ Differences in childhood and early adult circumstances are the underlying causes of social inequalities in both adult health behaviours and mortality. ▸ Policies focused only on adult health behaviours do not address the socially patterned causes of these behaviours or the independent role played by these causes in social inequalities in health. Contributors IG, PG, DK, EB, PH-C and MM made substantial contributions to the conception and design, acquisition of data, or analysis and interpretation of data; and the final approval of the version to be published.",[5],Medicine,train,5.0,news,http://www.healthcanal.com/public-health-safety/45052-tackling-early-socioeconomic-inequalities-as-important-as-encouraging-smoking-cessation.html
10.1073/pnas.1716802115,Medicine_easy_441,"Relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration, the effect of rising Max BMI was large.",The effect of rising Max BMI is large relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration.,"The results persisted with inclusion of other variables, differences in the measurement of Max BMI, and trend evaluation methods. Relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration, the effect of rising Max BMI was large. Over the period 1988 to 2011, the increase in Max BMI was estimated to have reduced life expectancy at age 40 years by 0.9 years and to account for 186,000 excess deaths in 2011.","Results were robust to the inclusion of other variables in the model, to differences in how Max BMI was measured, and to how trends were evaluated. The effect of rising Max BMI is large relative to international mortality trends and to alternative mortality futures simulated by the Social Security Administration. The increase in Max BMI over the period 1988-2011 is estimated to have reduced life expectancy at age 40 by 0.9 years in 2011 (95% confidence interval 0.7-1.1 years) and accounted for 186,000 excess deaths that year.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33026953578&p=1pl&v=1&x=jrNtJZM7DM5E6qfK_FW0VQ
10.1111/jth.13814,Medicine_easy_442,"""These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective,"" the authors write.",Conclusions: These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective.,"No pulmonary emboli, other thoracic, splanchnic, or ileofemoral vein thromboses were identified in standard protocol computed tomography scans of the chest/abdomen/pelvis that were obtained from 90.3 percent of patients. Two patients (1.6 percent) had minor bleeding events, and the severe complication rate was 5.6 percent, with no 90-day mortalities. ""These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective,"" the authors write.","The severe complication rate was 5.6%, with no 90-day mortalities. Conclusions: These preliminary data suggest that extended pharmacologic thromboprophylaxis for liver surgery patients is safe and effective. The intraoperative, postoperative and overall transfusion rates were 5.6%, 8.1%, and 10.5%, respectively.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/extended-thromboprophylaxis-safe-effective-after-liver-surgery/
10.1038/s41467-017-00706-1,Medicine_easy_444,"This allows the establishment of entanglement between two distant points without requiring one photon to travel the entire distance, thus reducing the effects of decay and loss.","This allows the establishment of entanglement between two distant points without requiring single photons to travel the entire distance, thus reducing the effects of decay and loss.","Increased bit rates can be achieved by using OAM as the carrier of information. This allows the establishment of entanglement between two distant points without requiring one photon to travel the entire distance, thus reducing the effects of decay and loss. It also means that you don't have to have a line of sight between the two places.","This work represents the first step towards a quantum network for high-dimensional entangled states and provides a test bed for fundamental tests of quantum science. This allows the establishment of entanglement between two distant points without requiring single photons to travel the entire distance, thus reducing the effects of decay and loss. Four of these subspaces did not show entanglement prior to the entanglement swapping.",[5],Medicine,train,5.0,news,http://www.spacedaily.com/reports/Researchers_demonstrate_quantum_teleportation_of_patterns_of_light_999.html
10.1001/jamainternmed.2018.2259,Medicine_easy_445,"""For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage,"" the authors write.","Meaning For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage.","No secondary outcomes (time to stone passage, return to work, use of analgesic medication, hospitalization, surgical intervention, and repeated emergency department visit) were significant. ""For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage,"" the authors write. ""Guidelines for medical expulsive therapy for urinary stones may need to be revised.""","Findings In this randomized clinical trial of 512 adults, the proportion achieving ureteral stone expulsion by 28 days was 50% with tamsulosin vs 47% with placebo, a nonsignificant difference. Meaning For emergency department patients who present with renal colic owing to ureteral stones smaller than 9 mm, tamsulosin does not appear to promote stone passage. In the 11 cases for which this algorithm did not yield a clear result, the CT scans were individually reviewed and a consensus was reached.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34693276968&p=1pl&v=1&x=zqMPUltMSVjgeeA6mHsw5Q
10.1001/jamapediatrics.2018.3101,Medicine_easy_446,"""Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children,"" the authors write.",Meaning Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children.,"For female children, the corresponding odds ratios were 1.03 (95 percent CI, 0.90 to 1.18), 0.98 (95 percent CI, 0.83 to 1.13), and 1.00 (95 percent CI, 0.86 to 1.16). ""Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children,"" the authors write. Abstract/Full Text (subscription or payment may be required)","Findings In this population-based cohort study of 132 256 births, maternal exposure to nitric oxide during pregnancy was associated with increased risk of autism spectrum disorder in offspring. Meaning Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children. The use of LUR models provides greater spatial resolution and the ability to capture small-scale, localized variation compared with reliance on air-quality monitoring data alone.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37748278537&p=1pl&v=1&x=7TKLTgqSS25asY1UBxk9OA
10.1016/j.clbc.2018.10.008,Medicine_easy_447,Both groups held weak beliefs about their need for tamoxifen for current and future health.,Both groups held weak beliefs about their need for tamoxifen for current and future health.,"One in five women (19.4 percent) reported a strong need for tamoxifen. Both groups held weak beliefs about their need for tamoxifen for current and future health. However, group 2 (38 percent of the sample) reported stronger concerns about tamoxifen and medicines in general and stronger perceived sensitivity to the negative effects of medicines compared with group 1 (the other 62 percent of the sample).","The model fit statistics supported a 2-group model. Both groups held weak beliefs about their need for tamoxifen for current and future health. Group 2 (38%; 154/406 of the sample) reported stronger concerns about tamoxifen and medicines in general, and stronger perceived sensitivity to the negative effects of medicines compared with group 1 (62%; 252/ 406).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37983548591&p=1pl&v=1&x=OvjaYTUHs99OZNUUnAjQsA
10.1186/s12879-018-3112-y,Medicine_easy_448,Organs should be discarded when rabies is confirmed or suspected.,Organs should be discarded whenever rabies is confirmed or suspected.,Serological testing and etiological diagnosis are recommended for donors with a high risk of rabies or clinically suspected of rabies. Organs should be discarded when rabies is confirmed or suspected. This is especially if the donor is diagnosed with encephalitis of unknown cause.,Four recipients developed rabies that was considered to be transmitted via organ transplantation. Organs should be discarded whenever rabies is confirmed or suspected. A supervisory system is needed to manage donorderived infectious diseases.,[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34929693402&p=1pl&v=1&x=Crzot8x-PtqrRp874qPYRw
10.1186/s13601-015-0055-x,Medicine_easy_449,"We believe that more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis.""","Consequently, more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis.","""Firstly, schools and daycares that allow peanuts may be doing a good job of controlling risk due to heightened awareness of the dangers. ""The most significant finding of this study is the discovery that most moderate and severe accidental exposures are managed inappropriately by caregivers and physicians. We believe that more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis.""","Conclusion: Despite increased awareness, accidental exposures continue to occur, mainly at home, and most are managed inappropriately by both health care professionals and caregivers. Consequently, more education is required on the importance of strict allergen avoidance and the need for prompt and correct management of anaphylaxis. Potential predictors for the Cox regression included sex, ethnicity, age at study entry, disease duration, source of recruitment (i.e., food allergy advocacy associations versus allergy clinics), other atopic conditions, severity of initial reaction to peanut, whether the child attended a school prohibiting peanut, and parental factors (i.e., living arrangement, age, level of education and employment).",[5],Medicine,train,5.0,news,http://www.newswise.com/articles/peanut-allergic-children-are-more-at-risk-of-exposure-at-home-than-at-school
10.1001/jamapediatrics.2018.0870,Medicine_easy_450,"When a single serum sample was analyzed from each of 317 patients, median viral loads did not differ significantly according to age, sex, or disposition.","When a single serum sample from each of 317 patients was analyzed, there were no statistically significant differences in median viral loads according to age, sex, or disposition.","The median viral load was higher in serum than in urine among children with serum and urine specimens collected on the same day. When a single serum sample was analyzed from each of 317 patients, median viral loads did not differ significantly according to age, sex, or disposition. The median serum viral load varied significantly according to the number of days after symptom onset, ranging from 106,778 copies/mL at zero days to 15,901 copies/mL at three or more days.","Of 131 children who had both serum and urine specimens collected on the same day, the median viral load was higher in serum than in urine (median [IQR], 23 098 [8784-88 242] copies/mL for serum vs 9966 [2815-52 774] copies/mL for urine; P = .02). When a single serum sample from each of 317 patients was analyzed, there were no statistically significant differences in median viral loads according to age, sex, or disposition. However, the median serum viral load varied significantly according to the number of days after the onset of symptoms (0 days CONCLUSIONS AND RELEVANCE This study represents the largest study to date of ZIKV infection in the pediatric population.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34198674076&p=1pl&v=1&x=IB7urjKbsD_fGqU6lpquOg
10.1038/s41746-018-0032-6,Medicine_easy_451,"""Furthermore, continuous activity monitoring may help predict and monitor treatment complications and allow for more timely and appropriate interventions.""","Furthermore, continuous activity monitoring during treatment could help predict and monitor treatment complications and allow for timely and appropriate intervention.","""Data gathered through advancements in technology has the potential to help physicians measure the impact of a particular treatment on a patient's daily functioning,"" Gresham said. ""Furthermore, continuous activity monitoring may help predict and monitor treatment complications and allow for more timely and appropriate interventions."" As a next step, investigators plan to study long-term use of the monitors in a larger, more diverse group of advanced cancer patients and correlate that data with clinical and self-reported outcomes.","Of additional importance is the possibility of combining objective activity monitoring data with electronically recorded PROs for the purpose of monitoring treatment tolerability and response in future clinical trials. Furthermore, continuous activity monitoring during treatment could help predict and monitor treatment complications and allow for timely and appropriate intervention. Although limited by its small size and short duration, our trial included participants of varying ECOG-PS and KPS ratings allowing for activity estimates in each of the performance status categories.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34627205538&p=1pl&v=1&x=nFGeRoOK2V_03Aqp23SUIQ
10.1001/jamapediatrics.2018.2537,Medicine_easy_452,"""Although identifying and treating ACE exposure is important, prioritizing primary prevention of ACEs is critical to improve health and life outcomes throughout the lifespan and across generations,"" the authors write.","Although identifying and treating ACE exposure is important, prioritizing primary prevention of ACEs is critical to improve health and life outcomes throughout the lifespan and across generations.","Participants who identified as black, Hispanic, or multiracial reported significantly higher ACE exposures (mean scores, 1.69, 1.8, and 2.52, respectively), as did those with less than a high school education (mean score, 1.97), those with income of less than $15,000 per year (mean score, 2.16), those who were unemployed or unable to work (mean scores, 2.3 and 2.33, respectively), and those identifying as gay/lesbian or bisexual (mean scores, 2.19, and 3.14, respectively). The most prevalent ACEs were emotional abuse, parental separation or divorce, and household substance abuse (34.42, 27.63, and 27.56 percent, respectively). ""Although identifying and treating ACE exposure is important, prioritizing primary prevention of ACEs is critical to improve health and life outcomes throughout the lifespan and across generations,"" the authors write.","These findings highlight that childhood adversity is common across sociodemographic characteristics, but some individuals are at higher risk of experiencing ACEs than others. Although identifying and treating ACE exposure is important, prioritizing primary prevention of ACEs is critical to improve health and life outcomes throughout the lifespan and across generations. T he foundation for lifelong health, well-being, and even prosperity is built in childhood.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=37160193461&p=1pl&v=1&x=6fvmQHbT6IVvjWqKYgg6uA
10.1001/jamainternmed.2017.7978,Medicine_easy_453,"""This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes,"" the authors write.",This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes.,"There was no modification of the effect by race, gestational diabetes, or parity. ""This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes,"" the authors write. ""Further investigation is required to elucidate mechanisms that may explain this relationship.""","There was no evidence of effect modification by race, GD, or parity. This study provides longitudinal biochemical evidence that lactation duration is independently associated with lower incidence of diabetes. Further investigation is required to elucidate mechanisms that may explain this relationship.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33026953525&p=1pl&v=1&x=fXymZlYbcgFBAOd5jAkOfA
10.1186/s12887-019-1528-1,Medicine_easy_454,"Academic performance and executive function scores were found to be positively correlated with age, gender, a- and g-tocopherol, TAC activity, and physical activity score; and negatively correlated with BMI.","The academic performance and executive function scores were found to be positively correlated with age, gender, α-and γ-tocopherol, TAC activity, and PA score; and negatively correlated with BMI.","""On the other hand, significantly higher levels of a- and g-tocopherol [and] total antioxidant capacity activity...were observed in participants in the moderate and high activity groups."" Academic performance and executive function scores were found to be positively correlated with age, gender, a- and g-tocopherol, TAC activity, and physical activity score; and negatively correlated with BMI. ""Children who face difficulties in learning may benefit from the provision of a balanced diet including vitamin E and other antioxidants,""  they suggested.","Groups of adolescents who were moderately of highly active were found to have significantly higher levels of vitamin E, TAC activity, LTPA, and academic performance compared with mildly active participants. The academic performance and executive function scores were found to be positively correlated with age, gender, α-and γ-tocopherol, TAC activity, and PA score; and negatively correlated with BMI. Vitamin E levels and TAC activity could be used as indicators for improving executive function, PA and academic performance among students.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39377367952&p=1pl&v=1&x=zEYBhT0yGmhwB_yLm12nhg
10.1186/s10194-018-0955-y,Medicine_easy_455,"""We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine,"" wrote the authors.After completing a review of available data, the researchers determined that erenumab, fremanezumab, and galcanezumab are effective for prevention in patients with episodic migraine.","Results: We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine.","However, in reviewing available research, the EHF found that there was not enough evidence to provide a guideline based on the Grading of Recommendation, Assessment, Development, and Evaluation approach. ""We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine,"" wrote the authors.After completing a review of available data, the researchers determined that erenumab, fremanezumab, and galcanezumab are effective for prevention in patients with episodic migraine. These drugs were found to reduce the number of headache or migraine days, reduce the number of days using acute medications, and improve disability.","Results: We found low to high quality of evidence to recommend eptinezumab, erenumab, fremanezumab, and galcanezumab in patients with episodic migraine and medium to high quality of evidence to recommend erenumab, fremanezumab, and galcanezumab in patients with chronic migraine. For several clinical questions, there was not enough evidence to provide recommendations using the GRADE approach and recommendations relied on experts' opinion. Conclusion: Monoclonal antibodies acting on the calcitonin gene-related peptide are new drugs which can be recommended for migraine prevention.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38762906591&p=1pl&v=1&x=c2w-_A1-a5S8NGK1QrFyyQ
10.1001/jamadermatol.2018.0233,Medicine_easy_456,"""Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care,"" the authors write.",Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care.,"Married patients were more likely to undergo sentinel lymph node biopsy in lesions with Breslow thickness >1 mm, for which it is routinely recommended, compared with never married, divorced, and widowed patients (odds ratios, 0.59, 0.87, and 0.69, respectively), independent of T stage and other patient factors. ""Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care,"" the authors write. Abstract/Full Text (subscription or payment may be required)","Moreover, never married, divorced, and widowed patients are less likely to undergo SLNB for appropriate lesions. Marital status should be considered when counseling patients for melanoma procedures and when recommending screening and follow-up to optimize patient care. [8] Among patients with clinically localized melanoma, a wide range in melanoma-specific survival is characterized by T stage and ulceration status.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33834316760&p=1pl&v=1&x=2_EXvE2OKA56huD06z1NXw
10.1186/s40337-019-0237-3,Medicine_easy_457,"On average, participants responded to 96% of the random prompts and reported 4 eating episodes per day.",Participants on average responded to 96% of the random prompts and reported 4 eating episodes per day.,"On average, participants responded to 96% of the random prompts and reported 4 eating episodes per day. Of the total eating episodes, 8% were characterized as OBE, and 43% of participants reported at least one OBE episode during the 3-day assessment. Between-person analyses were significant for negative affect (odds ratio, 1.93; P =.02), indicating a 93% increased risk for OBE among individuals with higher negative affect than those with average negative affect.","Level of participation was high. Participants on average responded to 96% of the random prompts and reported 4 eating episodes per day. Participants reported eating 1002 eating episodes during the 3-day period, 80 (8%) of which were characterized as OBE episodes.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39084406645&p=1pl&v=1&x=y6415bVDpIJumqEEqILv8g
10.1136/bmj.j5644,Medicine_easy_458,"""The beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity,"" the authors write.","Moreover, the beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity.","Among participants with low, intermediate, and high genetic risk, changes in body mass index per one standard deviation increment of AHEI-2010 score were -0.12, -0.14, and -0.18, respectively (weight changes of -0.35, -0.36, and -0.50 kg, respectively). ""The beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity,"" the authors write. Abstract/Full Text

Editorial (subscription or payment may be required)","These data indicate that improving adherence to healthy dietary patterns could attenuate the genetic association with weight gain. Moreover, the beneficial effect of improved diet quality on weight management was particularly pronounced in people at high genetic risk for obesity. Weights reported in questionnaires and measured by technicians were highly correlated (r=0.97 in both studies) in a validation subsample.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=32994759138&p=1pl&v=1&x=bIscXL-eokFPkbnRPYR7Vg
10.1542/peds.2013-2795,Medicine_easy_459,"Among youth with type 2 diabetes, DKA was much less common and decreased over time, suggesting improved detection or earlier diagnosis of diabetes.","Among youth with type 2 diabetes, DKA was less common and decreased by ∼10% per year, suggesting improved detection or earlier diagnosis.","Rates were disproportionately high in children younger than 5 years of age, non-White racial/ethnic groups, youth without private health insurance and those with lower family income. Among youth with type 2 diabetes, DKA was much less common and decreased over time, suggesting improved detection or earlier diagnosis of diabetes. Dabelea says ""These data suggest that more needs to be done to begin reducing DKA rates in the future.","WHAT THIS STUDY ADDS: DKA in youth with type 1 diabetes remains a problem, with almost one-third presenting with DKA. Among youth with type 2 diabetes, DKA was less common and decreased by ∼10% per year, suggesting improved detection or earlier diagnosis. In youth with type 1 diabetes (n = 5615), the prevalence of DKA was high and stable over time (30.2% in 2002-2003, 29.1% in 2004-2005, and 31.1% in 2008-2010; P for trend = .42).",[5],Medicine,train,5.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49282-burden-of-diabetic-ketoacidosis-still-unacceptably-high.html
10.1377/hlthaff.2015.0215,Medicine_easy_461,"They found that insurance application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst.","We found that application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst on most outcomes.","They found that insurance application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst. Latinos were equally likely to apply for coverage as other groups, but much less likely to complete the process and obtain coverage. Surprisingly, more than half of low-income adults in the study said they had heard little or nothing about the lawaEUR(tm)s new coverage options.","We found that application rates, successful enrollment, and positive experiences with the ACA were highest in Kentucky, followed by Arkansas, with Texas performing worst on most outcomes. Awareness of the ACA was low -less than half of adults had heard some or a lot about the law. Navigator assistance was the strongest predictor of successful enrollment, while Latinos were much less likely to complete the process.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/survey-finds-state-policies-have-critical-impact-on-aca-applications-enrollment/
10.1007/s00198-014-2732-3,Medicine_easy_464,"The researchers found that at the start of the study, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared to women who did not take calcium supplements.","At baseline, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared with those who did not take calcium supplements.","""Our study has several distinct strengths compared to prior studies including the large number of participants, long-term follow-up, large number of cardiovascular events that were confirmed by medical record review, detailed information about diet and other cardiovascular disease risk factors, and repeated assessment of calcium supplement use over the 24-year follow up period,"" said Julie Paik, MD, MPH, BWH Channing Division of Network Medicine, Department of Medicine, lead study author. The researchers found that at the start of the study, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared to women who did not take calcium supplements. During the 24 years of follow-up, there were 2,709 heart attacks and 1,856 strokes.","Results During 24 years of follow-up, 4,565 cardiovascular events occurred (2,709 CHD and 1,856 strokes). At baseline, women who took calcium supplements had higher levels of physical activity, smoked less, and had lower trans fat intake compared with those who did not take calcium supplements. After multivariable adjustment for age, body mass index, dietary calcium, vitamin D intake, and other CVD risk factors, the relative risk of CVD for women taking >1,000 mg/day of calcium supplements compared with none was 0.82 (95 % confidence interval [CI] 0.74 to 0.92; p for trend <0.001).",[5],Medicine,train,5.0,news,http://www.sciencedaily.com/releases/2014/05/140509130048.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamaophthalmol.2017.5470,Medicine_easy_465,"Eliciting or interpreting critical elements of history was the most common diagnostic error, which occurred in 33 percent of patients with alternative diagnoses.","The most common diagnostic error was eliciting or interpreting critical elements of history, which occurred in 24 of 73 patients (33%) with alternative diagnoses.","Headache and eye pain, functional visual loss, and other optic neuropathies were the most common alternative diagnoses. Eliciting or interpreting critical elements of history was the most common diagnostic error, which occurred in 33 percent of patients with alternative diagnoses. Errors weighing or considering alternative diagnoses, errors weighing or interpreting physical examination findings, and misinterpreting diagnostic test results were also common errors (32, 21, and 15 percent, respectively).","The most common alternative diagnoses were headache and eye pain, functional visual loss, and other optic neuropathies, particularly nonarteritic anterior ischemic optic neuropathy. The most common diagnostic error was eliciting or interpreting critical elements of history, which occurred in 24 of 73 patients (33%) with alternative diagnoses. Other common errors included errors weighing or considering alternative diagnoses (23 patients [32%]), errors weighing or interpreting physical examination findings (15 patients [21%]), and misinterpreting diagnostic test results (11 patients [15%]).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=32721477061&p=1pl&v=1&x=Y4NwLPnnNBNpNGFVlxe7_w
10.1001/jamaoncol.2017.1261,Medicine_easy_466,"""Women who have a tumor that is classified as ultralow risk by 70-gene signature can be reassured that their long-term outcome is expected to be excellent, with or without endocrine therapy.","Women who have a tumor that is an ultralow-risk tumor by 70-gene signature can be reassured that their long-term outcome is expected to be excellent, with or without endocrine therapy.","For ultralow risk elderly women over age 75 who have other conditions and face a life expectancy of less than a decade, simple excision may be sufficient, they said. ""Women who have a tumor that is classified as ultralow risk by 70-gene signature can be reassured that their long-term outcome is expected to be excellent, with or without endocrine therapy. Having a test that accurately identifies a population of women, who have very little risk to begin with, should be welcomed by patients and clinicians alike.","The ultralow-risk tumors are hormone-positive, mostly luminal A with low proliferation (Ki67 < 15%); however, they are only a small subset of cancers with those characteristics. Women who have a tumor that is an ultralow-risk tumor by 70-gene signature can be reassured that their long-term outcome is expected to be excellent, with or without endocrine therapy. In the tamoxifentreated arm, most had only 2 years of therapy and still had excellent long-term survival.",[5],Medicine,train,5.0,news,http://healthmedicinet.com/news/test-identifies-breast-cancer-patients-with-lowest-risk-of-death/
10.1016/j.yebeh.2013.06.008,Medicine_easy_470,"While 147 neurologists (29.1 percent) reported initiating carbamazepine treatment in Asian patients, only 33 of them (22.5 percent) said they performed haplotype screening.","While 147 neurologists (29.1%) reported initiating carbamazepine treatment in patients of Asian descent since the warning, only 33 of them (22.5%) said they performed haplotype screening.","The researchers found that 70 percent of the neurologists who responded knew of the recommendation. While 147 neurologists (29.1 percent) reported initiating carbamazepine treatment in Asian patients, only 33 of them (22.5 percent) said they performed haplotype screening. Eighteen neurologists reported that their Asian patients developed carbamazepine-related hypersensitivity reactions -- severe skin rashes that can lead to scarring, blisters in the mouth and shredding of the skin -- during this time period.","FDA recommendation to perform haplotype screening prior to initiating carbamazepine therapy in patients with Asian heritage Seventy percent of respondents reported that they were aware of this 2007 FDA recommendation. While 147 neurologists (29.1%) reported initiating carbamazepine treatment in patients of Asian descent since the warning, only 33 of them (22.5%) said they performed haplotype screening. Eighteen neurologists reported that their patients of Asian descent had developed carbamazepine-related hypersensitivity reactions during this time period.",[5],Medicine,train,5.0,news,http://www.healthcanal.com/brain-nerves/41944-many-neurologists-unaware-of-safety-risks-related-to-anti-epilepsy-drugs.html
10.5717/jenb.2014.18.3.249,Medicine_easy_471,"""It was concluded that the 12 weeks of vitamin D supplementation and circuit training would have positive effects on abdominal fat and blood lipid profiles in T2D and vitamin D deficient elderly women,"" wrote the researchers.",[Conclusion] It was concluded that the 12 weeks of vitamin D supplementation and circuit training would have positive effects on abdominal fat and blood lipid profiles in T2D and vitamin D deficient elderly women.,"Those in the vitamin D and circuit training group saw even more improvements, including lower fasting insulin and glucose levels. ""It was concluded that the 12 weeks of vitamin D supplementation and circuit training would have positive effects on abdominal fat and blood lipid profiles in T2D and vitamin D deficient elderly women,"" wrote the researchers. ""Vitamin D supplementation was especially effective when it was complemented with exercise training.""","4) Fasting glucose, fasting insulin, and HOMA-IR tended to be lower in D+T. [Conclusion] It was concluded that the 12 weeks of vitamin D supplementation and circuit training would have positive effects on abdominal fat and blood lipid profiles in T2D and vitamin D deficient elderly women. Vitamin D supplementation was especially effective when it was complemented with exercise training.",[5],Medicine,train,5.0,news,http://www.theepochtimes.com/n3/1224245-vitamin-d-combined-with-exercise-is-crucial-for-reversing-insulin-resistance-in-type-2-diabetics-study-shows/
10.1111/dom.13336,Medicine_easy_472,"There were non-linear associations with diabetes for age at menarche, parity, and age at first birth.","Non-linear associations with diabetes were observed for age at menarche, parity and age at first birth.","The researchers found that over a median follow-up of nine years, 4,073 cases of diabetes were reported. There were non-linear associations with diabetes for age at menarche, parity, and age at first birth. Menarche at <=10 years was associated with an 18 percent increased risk of diabetes after adjustment for BMI, compared with menarche at age 13 years.","Results: Over a median follow-up of 9 years, 4073 cases of diabetes were reported. Non-linear associations with diabetes were observed for age at menarche, parity and age at first birth. Notable trends in the prevalence of female-specific risk factors such as an increase in the rate of gestational diabetes (itself, a major risk factor for diabetes) observed in populations, 11 and a decline in the mean age of menarche 12 (in part attributable to the increase in childhood obesity) have added to the speculation that they may play a role in the diabetes pandemic.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33959353279&p=1pl&v=1&x=fJcnxDYhIvLteA1Lt9SuQA
10.1089/apc.2017.0171,Medicine_easy_473,"""This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups,"" study authors noted.","This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups.","Lack of insurance was cited as a barrier by 15% of respondents who did not use PrEP. ""This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups,"" study authors noted. Regional disparities must also be overcome.","These regional disparities might reflect the more limited expansion of Medicaid in the south than in the rest of the country. This finding is particularly troubling, given that the highest rates of new HIV infection are in the South, and southern blacks have a higher prevalence of HIV there than other ethnic groups. Lower education frequently coincides with lower health literacy and reduced knowledge of preventive services such as PrEP.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=33794251881&p=1pl&v=1&x=FcO5IgoNkIDHnFFfmx6DSQ
10.1001/jamacardio.2018.1511,Medicine_easy_474,"""Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention,"" the authors write.","Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention.","After adjustment for demographic, clinical, and clinician factors; socioeconomic status; and patient beliefs, the group differences in statin undertreatment were not significant. ""Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention,"" the authors write. Several authors disclosed financial ties to pharmaceutical companies, including Sanofi and Regeneron Pharmaceuticals, both of which partially funded the PALM Registry.","CONCLUSIONS AND RELEVANCE African American individuals were less likely to receive guideline-recommended statin therapy. Demographic, clinical, socioeconomic, belief-related, and clinician differences contributed to observed differences and represent potential targets for intervention. Part of the explanation for this increased risk may be undertreatment of African American peoples for primary prevention.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=34305773648&p=1pl&v=1&x=SRMGhcUEOmnUBC4TA3jq6w
10.1007/s10549-019-05226-8,Medicine_easy_475,Significantly smaller increases in 10-year DR rates with the increasing EPclin score were seen for women who received ET + C compared with those receiving ET alone (EPClin = 5; 12 percent for ET + C versus 20 percent for ET alone).,Women who received ET + C had significantly smaller increases in 10-year DR rates with the increasing EPclin score than those receiving ET alone (EPclin = 5; 12% ET + C vs. 20% ET alone).,"The researchers found that in women who received ET alone and in those who received ET + C, EPclin was highly prognostic for DR (hazard ratios, 2.79 and 2.27, respectively). Significantly smaller increases in 10-year DR rates with the increasing EPclin score were seen for women who received ET + C compared with those receiving ET alone (EPClin = 5; 12 percent for ET + C versus 20 percent for ET alone). A significant positive interaction was seen between EPclin and treatment groups.","Results EPclin was highly prognostic for DR in women who received ET alone (HR 2.79 (2.49-3.13), P < 0.0001) as well as in those who received ET + C (HR 2.27 (1.99-2.59), P < 0.0001). Women who received ET + C had significantly smaller increases in 10-year DR rates with the increasing EPclin score than those receiving ET alone (EPclin = 5; 12% ET + C vs. 20% ET alone). We observed a significant positive interaction between EPclin and treatment groups (P-interaction = 0.022).",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=39175818639&p=1pl&v=1&x=xKDJaFBDNHKJMwZHYcOoJQ
10.1038/nature22346,Medicine_easy_476,A confirmation of these results would point to new particles or interactions and could have profound implications for the understanding of particle physics.,"A confirmation of these results would point to new particles or interactions, and could have profound implications for our understanding of particle physics.","However, Franco Sevilla noted, the fact that all three experiments observed a higher-than-expected tau decay rate while operating in different environments is noteworthy. A confirmation of these results would point to new particles or interactions and could have profound implications for the understanding of particle physics. ""We're not sure what confirmation of these results will mean in the long term,"" Franco Sevilla said.","For purely leptonic B − decays, the standard model prediction of the total decay rate Γ, which depends critically on the lepton mass squared m ℓ 2 , is: One of the key assumptions of the standard model of particle physics is that the interactions of the charged leptons, namely electrons, muons and taus, differ only because of their different masses. A confirmation of these results would point to new particles or interactions, and could have profound implications for our understanding of particle physics. SM 0 05 0 10 4 Decays to the lower-mass charged leptons, e − and μ − , are strongly suppressed by spin effects and have not yet been observed.",[5],Medicine,train,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/VPxE-tYPN_o/
10.1001/jamasurg.2018.4608,Medicine_easy_478,"""In urgent situations, patients need not be denied cardiac surgery because of their OUD status, although close postoperative monitoring is suggested,"" the authors write.","In urgent situations, patients need not be denied cardiac surgery because of their OUD status, although close postoperative monitoring is suggested.","They also had a significantly longer length of stay (median, 11 versus 10 days; P < 0.001) and higher cost per patient ($49,790 versus $45,216; P < 0.001). ""In urgent situations, patients need not be denied cardiac surgery because of their OUD status, although close postoperative monitoring is suggested,"" the authors write. Abstract/Full Text (subscription or payment may be required)","In conclusion, preoperative OUD in cardiac surgery patients does not increase mortality but confers an increased burden of morbidity and resource utilization. Trends in patient volume and morbidity reported in our study suggest that cardiac surgeons are likely to encounter this population of patients more often now than in the past and should be prepared to adequately manage the perioperative factors specific to them. In urgent situations, patients need not be denied cardiac surgery because of their OUD status, although close postoperative monitoring is suggested.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38086062320&p=1pl&v=1&x=7OYx6eU_dmAY0OnM1eTLzg
10.1016/j.juro.2016.08.007,Medicine_easy_480,"""Men's level of emotional distress shortly after diagnosis predicted greater likelihood of choosing surgery over active surveillance,"" the researchers report.",The level of emotional distress in men shortly after diagnosis predicted a greater likelihood of choosing surgery over active surveillance.,"The majority of study participants had either low- or intermediate-risk disease, and were more likely to have been treated with surgery, followed by radiation and active surveillance. ""Men's level of emotional distress shortly after diagnosis predicted greater likelihood of choosing surgery over active surveillance,"" the researchers report. ""Importantly, this was true among men with low-risk disease, for whom active surveillance may be a clinically viable option and side effects of surgery might be avoided.""","Being older was associated with a lower likelihood of choosing surgery over active surveillance or radiation. The level of emotional distress in men shortly after diagnosis predicted a greater likelihood of choosing surgery over active surveillance. Importantly, this was true for men with low risk disease, for whom active surveillance may be a clinically viable option and the side effects of surgery or radiation might be unnecessary.",[5],Medicine,train,5.0,news,http://www.futurity.org/prostate-cancer-anxiety-1333372-2/
10.1001/jama.2019.1432,Medicine_easy_481,"The authors concluded: ""In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia.""","In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia.","Of the 8,255 total, 344 participants had developed dementia in the 25 years following the start of the study. The authors concluded: ""In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia."" ""This was a robust study that followed participants over a long time, but was based on self-reported feedback from the participants on their diet, which may not always be accurate.","Fourth, as with all observational studies, it was not possible to rule out residual confounding. In this long-term prospective cohort study, diet quality assessed during midlife was not significantly associated with subsequent risk for dementia. The validity and reliability of this version of the FFQ in terms of nutrient and food consumption has been documented in detail both in this cohort and in another independent study in the United Kingdom.",[5],Medicine,train,5.0,news,http://ct.moreover.com/?a=38752330367&p=1pl&v=1&x=xgPuP-sFG5bg4SZUexf-TA
10.1093/jnci/dju237,Medicine_easy_483,"""Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality,"" concluded the authors.",Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality.,"The risk of ER-negative breast cancer increased with each subsequent birth among those women who did not breastfeed (odds ratio of 1.68 for four or more births compared with one birth for a woman who breastfed). ""Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality,"" concluded the authors. The finding may explain why African American women, who typically have more children but have lower rates of breastfeeding compared with American white women, are disproportionately affected by ER-negative breast cancer, stated the authors.","The findings suggest that parous women who have not breastfed are at increased risk of ER-and triple-negative breast cancer. Promotion of lactation may be an effective tool for reducing occurrence of the subtypes that contribute disproportionately to breast cancer mortality. If so, the higher parity and lower prevalence of lactation in AA women relative to white women could be a contributor to the racial disparity in ER-cancer.",[5],Medicine,train,5.0,news,http://www.cancernetwork.com/triple-negative-breast-cancer/breastfeeding-reduces-breast-cancer-risk-black-women
10.1016/j.jtho.2016.01.011,Medicine_easy_484,"""This paper validates H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between lung cancer patients and controls,"" stated the authors.","In conclusion, this paper validates 1 H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between patients with lung cancer and controls.","The model had a sensitivity of 71% and a specificity of 81%; however, it could not discriminate between histologic subtypes and tumor stages. ""This paper validates H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between lung cancer patients and controls,"" stated the authors. ""Our findings indicate that while metabolic alterations can be detected at an early stage, our intent is not to use the metabolome as a separate screening tool but to complement current risk models with additional parameters to better select high-risk individuals eligible for LDCT screening.""","These findings indicate that lung cancer cells utilize at least some steps of the gluconeogenic pathway to adapt to low-glucose conditions as a result of insufficient blood flow. In conclusion, this paper validates 1 H-NMR metabolic phenotyping of blood plasma as a complementary tool to discriminate between patients with lung cancer and controls. Our findings indicate that metabolic alterations can already be detected in an early stage.",[5],Medicine,train,5.0,news,http://www.oncologynurseadvisor.com/unique-metabolic-biomarkers-specific-to-lung-cancer-found/article/482912/
10.1038/s41586-018-0150-y,Medicine_easy_485,What happened next astonished them.,"v, GBX2 is expressed in the host and in the graft-induced secondary axis.","There is a difference between what cells can do in a Petri dish, however, and what they will do inside a real embryo. What happened next astonished them. Yet as soon as they were introduced to their avian hosts, the human cells began laying the groundwork for a secondary spinal column and nervous system--an act that clearly announced the presence of a true human organizer.","u, HOXB1 is expressed in the host and in the graft-induced secondary axis. v, GBX2 is expressed in the host and in the graft-induced secondary axis. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.",[1],Medicine,train,1.0,news,https://www.futurity.org/stem-cells-embryos-1771882-2/
10.1038/s41598-017-18681-4,Medicine_easy_486,En net als ieder ander middel zijn ze niet onfeilbaar.,"Another point to be noted is the following: Here, the interaction parameter is chosen as Q = γρ dm ρ de .","Misschien dat digitale computers en modellen weliswaar handige middelen zijn om de wereld beter te begrijpen, maar ook weer niet veel meer dan dat. En net als ieder ander middel zijn ze niet onfeilbaar. We moeten er rekening mee blijven houden dat ze er net zo goed naast kunnen zitten.","In fact this model establishes lower and upper boundaries for the EoS parameters of dark energy. Another point to be noted is the following: Here, the interaction parameter is chosen as Q = γρ dm ρ de . This implies that the transformation between dark energy and dark matter will be equal for both directions.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=40290578371&p=1pl&v=1&x=qYzyuuN_ge5s0bCN6R9APA
10.4049/jimmunol.1502483,Medicine_easy_487,"""If we can instead vaccinate mom or boost her vaccination shortly before she becomes pregnant, transferred immune cells during breast feeding will ensure that the baby is protected early on.","This mechanism is consistent with the observation that a significant proportion of transferred maternal cells: 1) had a memory phenotype; 2) were Ag-specific by tetramer staining; or 3) when in the spleen, responded to Ag by the production of appropriate cytokines.","The researchers show that you can vaccinate the mother and this results in vaccination of the baby through this process. ""If we can instead vaccinate mom or boost her vaccination shortly before she becomes pregnant, transferred immune cells during breast feeding will ensure that the baby is protected early on. ""We hope that by vaccinating the mother, who will eventually nurse the baby, we will improve infant immunity against TB,"" Walker said.","The mechanisms by which CD4 + T cells can acquire MHCII seem to be fewer in mice than humans . This mechanism is consistent with the observation that a significant proportion of transferred maternal cells: 1) had a memory phenotype; 2) were Ag-specific by tetramer staining; or 3) when in the spleen, responded to Ag by the production of appropriate cytokines. Importantly, Umeshappa et al.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/lnaDDxms29c/
10.1016/j.neuropharm.2018.11.016,Medicine_easy_488,Esto se conoce como extincion del miedo.,"S7A ) and the IL (interaction THC x stress: F 1,22 = 5.66, p < 0.05) (Fig.","Normalmente, las reacciones de miedo disminuyen con el tiempo a medida que el estimulo deja de asociarse con la experiencia negativa. Esto se conoce como extincion del miedo. ""Hemos observado que ratones adolescentes tratados con THC y expuestos al estres exhiben un deterioro en la extincion del miedo en la edad adulta.","Simultaneous THC and stress adolescent exposure reduced the activity of the BLA (interaction THC x stress: F 1,23 = 9.52, p < 0.05) (Fig. S7A ) and the IL (interaction THC x stress: F 1,22 = 5.66, p < 0.05) (Fig. Interestingly, cFos expression was higher in adult animals exposed to THC and stress during the adolescence that did not undergo fear conditioning/extinction in both the BLA (p < 0.05) (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38133740347&p=1pl&v=1&x=f5RA8MMV5XZmwk4nj7ktlg
10.1038/s41467-018-08119-4,Medicine_easy_489,"Flipping the quantum switch

Using this system, researchers can literally turn spin-orbit coupling on and off, which allows them to isolate its effect on spin current decay.","In addition, all the effective interaction parameters would approach the corresponding bare values, i.e., g ↑ ↑ → g ↑↑ , g ↓ ↓ → g ↓↓ , and g ↑ ↓ → g ↑↓ .","""Because we can control every parameter, this is a really efficient system to study these kinds of collisions."" Flipping the quantum switch

Using this system, researchers can literally turn spin-orbit coupling on and off, which allows them to isolate its effect on spin current decay. This can't be done with electrons in solid-state materials, which is part of what makes this system so powerful, Chen says.","As we can see, either decreasing Ω or increasing q y would decrease θ qy (or increase cos θ qy ). In addition, all the effective interaction parameters would approach the corresponding bare values, i.e., g ↑ ↑ → g ↑↑ , g ↓ ↓ → g ↓↓ , and g ↑ ↓ → g ↑↓ . On the other hand, either increasing Ω or decreasing q y would increase θ qy towards π/2 (or decrease cos θ qy ), thus enhancing the bare spin mixing, nonorthogonality and g ↑ ↓ .",[1],Medicine,train,1.0,news,https://www.futurity.org/quantum-system-for-spintronics-1972642/
10.1038/s41598-017-00678-8,Medicine_easy_491,"It seemed to increase students' level of physical, mental and emotional awareness.",The shortest path length L ij between node i and j is the length of the path with the shortest length between the 2 nodes.,"Meditation allowed them to know themselves better, helping them feel more relaxed and peaceful. It seemed to increase students' level of physical, mental and emotional awareness. Moreover, students also reported waking dreams, visions and a sense of tranquility during meditation.",The global efficiency of G can be computed as: The shortest path length L ij between node i and j is the length of the path with the shortest length between the 2 nodes. Shortest path length.,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33999175752&p=1pl&v=1&x=8DSh2p-NEYJL7vSaxYifuA
10.1001/jamainternmed.2017.5038,Medicine_easy_492,There's bound to be a lot of hand-wringing over this in certain corners of the internet.,Similar trends were observed with greater intake of low-pesticide residue FVs except that no difference in prevalence of diminished ovarian reserve was observed.,"It seems that eating fruits and vegetables that are known to have high pesticide residues could make it harder to get pregnant. There's bound to be a lot of hand-wringing over this in certain corners of the internet. So, I want to put these findings in perspective for those of you who are trying to conceive as well as anyone who is just generally concerned about pesticides and their effects on health.","Women who consumed more high-pesticide residue FVs were more likely to report regular organic FV consumption, had higher total calorie and micronutrient intake, higher adherence to the prudent dietary pattern, and a slightly higher prevalence of diminished ovarian reserve. Similar trends were observed with greater intake of low-pesticide residue FVs except that no difference in prevalence of diminished ovarian reserve was observed. Other characteristics were similar across quartiles of high-or low-pesticide FV intake ( Table 2) .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33322911082&p=1pl&v=1&x=r2UbM3QJAND2ZMUx0DoPKQ
10.1073/pnas.1514699113,Medicine_easy_493,"If shame is a defense against devaluation, then the intensity of shame associated with an act should move up or down in lockstep with the degree to which others in your community would devalue you (if they knew your behavior).","Yes (see Table 1 , diagonal values).","Depending on the aversive magnitude of the anticipated shame, individuals will often be deterred from behaviors that hurt or destroy their relationships with the people around them -- or they will be motivated to hide them. If shame is a defense against devaluation, then the intensity of shame associated with an act should move up or down in lockstep with the degree to which others in your community would devalue you (if they knew your behavior). ""We observed a surprisingly close match between the negative reactions to people who commit each of these acts -- that is, the magnitudes of devaluation -- and the intensities of shame felt by individuals imagining that they would commit those acts,"" Cosmides said.","3. Yes (see Table 1 , diagonal values). Shame and devaluation means were highly correlated with one another in each country, with a mean r of .72 and a range of rs of .67-.79.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/8ZfHYeQdk9w/
10.1126/science.aat3466,Medicine_easy_495,"They found that rising global temperatures would lead to an increase in crop losses from insects, especially in temperate regions.","As a result, the increase in pest-related crop loss is consistently larger than in tropical regions, where the increasing metabolic rate is offset by declining population growth rates, resulting in a smaller overall rise in crop damages.","""We are going to see increased pest pressure from climate change."" They found that rising global temperatures would lead to an increase in crop losses from insects, especially in temperate regions. Losses are projected to rise by 10 to 25% per degree of warming.","In temperate regions, warming increases both the size of insect populations and their per capita metabolic rate (Fig. As a result, the increase in pest-related crop loss is consistently larger than in tropical regions, where the increasing metabolic rate is offset by declining population growth rates, resulting in a smaller overall rise in crop damages. This broad geographic pattern holds across all crops, climate models, and life history parameters considered ( Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34960791264&p=1pl&v=1&x=xXKZ8HOVq-LOHSdbqTvAUg
10.1016/j.cell.2017.07.013,Medicine_easy_497,"""Initially, we did not expect the outcome would come out this way,"" Tonegawa says.","The AAV 9 -EF1a-DIO-mCherry, AAV 9 -EF1a-DIO-eArch3.0-mCherry, and AAV 9 -EF1a-eArch3.0-eYFP viruses were acquired from Vector BioLabs.","Other experiments revealed that the direct circuit from CA1 to the entorhinal cortex is not necessary for memory recall, but is required for memory formation. ""Initially, we did not expect the outcome would come out this way,"" Tonegawa says. The researchers found evidence for two possible explanations.","The AAV 9 -EF1a-DIO-eYFP, AAV 9 -EF1a-DIO-ChR2-eYFP, and AAV 9 -EF1a-DIO-eArch3.0-eYFP viruses were acquired from the University of North Carolina (UNC) at Chapel Hill Vector Core. The AAV 9 -EF1a-DIO-mCherry, AAV 9 -EF1a-DIO-eArch3.0-mCherry, and AAV 9 -EF1a-eArch3.0-eYFP viruses were acquired from Vector BioLabs. Viral titers were 1.2 3 10 13 genome copy (GC) mL -1 for AAV 9 -EF1a-DIO-eYFP, 4 3 10 12 GC mL -1 for AAV 9 -EF1a-DIO-ChR2-eYFP, 1.6 3 10 13 GC mL -1 for AAV 9 -EF1a-DIO-eArch3.0-eYFP, 3 3 10 13 GC mL -1 for AAV 9 -EF1a-DIO-mCherry and AAV 9 -EF1a-DIO-eArch3.0-mCherry, 1 3 10 11 GC mL -1 for AAV 9 -EF1a-eArch3.0-eYFP, 4 3 10 12 GC mL -1 for AAV 2 -Syn-DIO-GCaMP6f and AAV 5 -Syn-DIO-GCaMP6f, 1.1 3 10 13 GC mL -1 for AAV 8 -CMV-DIO-Synaptophysin-mCherry, 2 3 10 14 GC mL -1 for AAV 9 -EF1a-DIO-H2B-GFP, 4 3 10 13 GC mL -1 for AAV 9 -c-Fos-tTA, 1.4 3 10 13 GC mL -1 for AAV 5 -TRE-H2B-GFP, and 1.5 3 10 13 GC mL -1 for AAV 9 -TRE-ChR2-eYFP.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/how-we-recall-the-past-neuroscientists-discover-a-brain-circuit-dedicated-to-retrieving-memories/
10.1016/j.cell.2013.05.002,Medicine_easy_498,"These tests largely stopped with the Limited Test Ban Treaty of 1963, but their effects remained in the atmosphere.",Analysis of the number of neuronal progenitor cells gives an indirect indication of the possible extent of neurogenesis.,"The oldest person in the study was 72, suggesting new neuron creation, known as neurogenesis, continues well into old age. These tests largely stopped with the Limited Test Ban Treaty of 1963, but their effects remained in the atmosphere. The neutrons sent flying by the bombs reacted with nitrogen in the atmosphere, creating a spike in carbon 14, an isotope (or variation) of carbon.",The similar decline in neuroblast numbers in the subventricular zone and the hippocampus poses the question of whether there is postnatal hippocampal neurogenesis in humans to an extent that may have an impact on brain function. Analysis of the number of neuronal progenitor cells gives an indirect indication of the possible extent of neurogenesis. The cumulative nature of 14 C integration makes the method especially suited for establishing the kinetics of slowly turning over cell populations.,[1],Medicine,train,1.0,news,http://www.livescience.com/37226-bomb-tests-reveal-new-neurons.html
10.1016/j.neuron.2014.01.025,Medicine_easy_499,"""As an engineer, I can't design a circuit that would do that,"" Stanley said.","Taken together, the spiking activity measured in the VPm thalamus of the awake animal strongly mirrored the behavioral findings obtained throughout the study.","But in the brain, a pathway adaptively changes between being good at detecting something to being good at discriminating something, the study showed. ""As an engineer, I can't design a circuit that would do that,"" Stanley said. Learning more about how circuits in the brain multitask could lead to a better understanding of disease, therapeutic applications or to potentially improving how the brain functions.","Similarly, timing precision as measured using TC40 was reduced to 81% ± 3.0% of the nonadapted value with a short period of recovery (p < 0.005, n = 43, paired t test) and increased to 87% ± 3.0% of its nonadapted value (p < 0.05, n = 43, paired t test) with additional recovery time (Figure 6D) . Taken together, the spiking activity measured in the VPm thalamus of the awake animal strongly mirrored the behavioral findings obtained throughout the study. The Spatial Discrimination Performance of the Animals Is Improved with Adaptation (A) Discrimination task.",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/brain-circuits-multitask-to-detect-discriminate-the-outside-world
10.1098/rspb.1998.0302,Medicine_easy_500,"Males and females, they found, oftentimes both began from the same brightly colored starting point.","Ellipsoid models are valid if the thresholds are small compared to nonlinearities in signal processing, or when discrimination is limited by noise in receptors and in opponency channels.","This allowed them to standardize and compare colors between the sexes and within and between bird species according to how birds perceive color rather than how people see it. Males and females, they found, oftentimes both began from the same brightly colored starting point. But the females' rate of evolutionary change tended to outpace their male counterparts, allowing the fairer sex of many species to, well, lose their ""fairness"" and quickly shed their color, while males evolved at a slower step toward more gaudy patterns.","Models which describe sensitivity to small di¡erences by ellipsoids of colour mismatches are useful for predicting contours of equal discriminability in a perceptual space . Ellipsoid models are valid if the thresholds are small compared to nonlinearities in signal processing, or when discrimination is limited by noise in receptors and in opponency channels. the number of parameters exceeds the number of receptor types.",[1],Medicine,train,1.0,news,http://www.smithsonianmag.com/science-nature/drab-female-birds-were-once-flashy-their-male-mates-180951427/
10.3109/15563650.2015.1110590,Medicine_easy_501,"In this way, the more adverse effects observed with synthetic cannabis use stem from its ability to completely saturate and activate all of the body's cannabinoid receptors at a lower dose.","58 Hospitalization lasted between 6-10 days and in one case, symptoms persisted for more than five months.","This is because, while the THC in natural cannabis only partially reacts with the body, synthetic cannabis reacts far more fully. In this way, the more adverse effects observed with synthetic cannabis use stem from its ability to completely saturate and activate all of the body's cannabinoid receptors at a lower dose. Different brands of smoking mixtures can have very different effects, but the strength of a specific brand appears to owe more to the ratio of cannabinoids to chemically inactive plant material in the mixture, rather than the variation in the chemical structure of compounds themselves.","Hurst et al reported on 10 cases of new onset psychosis associated with SC use from San Diego, although only two involved just the use of SCs, with the remainder consuming cannabis or alcohol either concurrently or in the recent past. 58 Hospitalization lasted between 6-10 days and in one case, symptoms persisted for more than five months. An audit of an open adult ward in New Zealand found 13% (n=17) of psychiatric admissions were probably related to SC consumption, including four first time admissions (affective, suicidal or psychotic symptoms) plus four first admissions with psychosis.",[1],Medicine,train,1.0,news,http://www.theepochtimes.com/n3/2169878-what-is-spice-and-why-is-the-drug-so-dangerous/
10.1186/1471-2105-15-328,Medicine_easy_502,"With a little help from a team of engineers at Drexel University, these scientists could soon be donning 3-D glasses in a home-theater-like lab to take their own fantastic voyage into the petri dish.",The delta for each node connected to this root node is based only on the registration position change.,"With a little help from a team of engineers at Drexel University, these scientists could soon be donning 3-D glasses in a home-theater-like lab to take their own fantastic voyage into the petri dish. ""This type of imaging is so important because it allows us to see and measure relationships between cells and their environment,"" Cohen said. LEVER is easier and more accurate than processing the data manually and also provides more data than what can be obtained by hand.",This technique also works directly on the images rather than requiring preprocessing to determine a set of feature points that are used in more complex registration schemes. The delta for each node connected to this root node is based only on the registration position change. The final positions can be viewed as the red lines in Figure 2 .,[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141003214351.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41467-018-07290-y,Medicine_easy_503,"For further information, please contact the cited source.",This sensing-and-protrusion matrix facilitates high spatial segregation of adhesion ligands but retains biomechanical coupling between the two systems 48 .,"Within a few years, the researchers hope to move to clinical trials in humans. Note: material may have been edited for length and content. For further information, please contact the cited source.","Combined, this suggests a model where a wellestablished multitude of interactions between MTs and contracting peripheral F-actin stress-fibers (via conventionally known MT-actomyosin interactions adaptors, such as myosin, and TIP 50 and septin 49 complex, which can be overexpressed in some carcinoma cells 52 ) are necessary to promote Arp2/3-dependent uniaxial dimensionality commitment on biaxial contact guidance cues (Fig. This sensing-and-protrusion matrix facilitates high spatial segregation of adhesion ligands but retains biomechanical coupling between the two systems 48 . We confirmed the specificity of the collagen and E-cadherin ligands through immunofluorescence staining, where no cross-reactivity was observed (Supplementary Figure 9) .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37755115692&p=1pl&v=1&x=-Mn9Lv5PBlXV6JRvBL7A3Q
10.1186/1750-1326-10-2,Medicine_easy_504,In this field studying sAPP and its fragments could be extremely useful.,"In the absence of capture-antibody (IPc), or when a rabbit IgG was used for immunoprecipitation (not shown), no bands were observed on the immunoblots ( Figure 1C, D) .","Professor Saez Valero, along with Inmaculada Cuchillo and Inmaculada Lopez, main authors of the study, explain that this finding opens the possibility of designing new tests applicable in the early diagnosis and clinical trials, in order to effectively estimate the value of sAPP as a biomarker for Alzheimer's. The validation of new biomarkers for clinical diagnosis of Alzheimer's disease in its early stages is a priority for the appropriate therapeutic intervention of disease. In this field studying sAPP and its fragments could be extremely useful.","We do not exclude that some of the 6E10 immunoreactivity detected in Sigma-Ct immunoprecipitates arises from sAPPα forms, reflecting the presence of heteromers containing sAPPf and sAPPα. In the absence of capture-antibody (IPc), or when a rabbit IgG was used for immunoprecipitation (not shown), no bands were observed on the immunoblots ( Figure 1C, D) . The major APP band in the brain was identified at~240 kDa with the 6E10 antibody.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150204075222.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_health+%28ScienceDaily%3A+Top+Health+News%29
10.1016/j.cub.2018.03.039,Medicine_easy_505,As moscas macho procuram um par para acasalar atraves de melodias criadas pelas vibracoes de suas asas para atrair femeas e entao poderem ejacular.,None of the genotypes showed a significant preference for the activation zone when both sides of the arena were un-illuminated ( Figure 1C) .,"Outra maneira eficiente de diferencia-las e atraves do comprimento do seu corpo, se a mosca e curta e de cauda redonda, entao e macho. As moscas macho procuram um par para acasalar atraves de melodias criadas pelas vibracoes de suas asas para atrair femeas e entao poderem ejacular. A investigacao continuou quando puseram as moscas modificadas em um quarto com iluminacao vermelha, onde notaram que os insetos preferiam ficar debaixo da luz, ja que ela causava uma ejaculacao.","For example, in a two-choice preference assay, flies prefer to reside in a zone where they receive optogenetic stimulation of reward-encoding neurons . None of the genotypes showed a significant preference for the activation zone when both sides of the arena were un-illuminated ( Figure 1C) . CRZ > CsChrimson males, but not genetic controls, showed a strong positional preference for the illuminated zone during the two-choice phase ( Figures 1D and 1E ).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34574646081&p=1pl&v=1&x=SvgIniugq6r2rX-R8WD__A
10.1073/pnas.1703200114,Medicine_easy_507,"Instead, they simply need to wash the slide in a buffer solution to remove any extraneous particles.","In both cases, as expected the data show good correspondence with ELISA values (dashed black trace).","Using the D4 assay, researchers don't need to follow a complicated workflow to clear non-target proteins from their slide, as with the ELISA test. Instead, they simply need to wash the slide in a buffer solution to remove any extraneous particles. Leptin levels are typically measured using ELISA, but the researchers recognized that if they could use the D4 assay to accurately test for leptin levels, the tool could be used to plan better treatment for those suffering from malnutrition in resource-limited settings.","In this experiment, the scanner was more sensitive than the mobile phone, with LODs determined to be 0.037 ng/mL and 0.71 ng/mL, respectively. In both cases, as expected the data show good correspondence with ELISA values (dashed black trace). Transitioning to the mobile phone-based detection platform reduced detection sensitivity and interassay consistency, as seen by the higher LOD and larger error bars with the mobile phone device.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/printable-tool-enables-sensitive-diagnostic-testing/
10.1016/j.canlet.2014.04.014,Medicine_easy_508,"Unfortunately, four years after Dr. Warburg gave this statement, he died.","Intriguingly, OGA is a bifunctional enzyme harboring O-GlcNAc cleavage activity as well as HAT activity, implying an intrinsic relationship between histone O-GlcNAcylation and acetylation.","From the standpoint of the physics and chemistry of life this difference between normal and cancer cells is so great that one can scarcely picture a greater difference. Unfortunately, four years after Dr. Warburg gave this statement, he died. It's not something that is openly publicized, it seems.","Additionally, H2B monoubiquitination facilitates H3K4 and H3K79 methylation . Intriguingly, OGA is a bifunctional enzyme harboring O-GlcNAc cleavage activity as well as HAT activity, implying an intrinsic relationship between histone O-GlcNAcylation and acetylation. Sakabe and Hart reported that both OGT catalytic activity and O-GlcNAc levels on histones (particularly H3) are reduced during early mitosis and are gradually increased during late mitosis to G1 phase .",[1],Medicine,train,1.0,news,http://www.inquisitr.com/1834216/two-cancer-doctors-were-possibly-silenced-about-its-main-causes-see-why-they-say-the-disease-forms/
10.1001/jama.299.24.2884,Medicine_easy_510,During the transition period there were some challenges for physicians and secretaries.,"The same limitation of studies on EMI by mobile phones, generalization of demonstrated EMI incidents, applies to the present study on RFID.","This allowed doctors and secretaries to make all the necessary adjustments and distribute documentation quickly enough to meet treatment guidelines. During the transition period there were some challenges for physicians and secretaries. Despite this, even the initial speech recognition results were very high - as high as 97% and 100%.","The 30-cm median distance for all incidents found with RFID might be more critical compared with the median range of 3 cm with modern mobile phones. The same limitation of studies on EMI by mobile phones, generalization of demonstrated EMI incidents, applies to the present study on RFID. Our results apply only on the technology of 1 active and 1 passive RFID system from 2 specified manufacturers.",[1],Medicine,train,1.0,news,http://www.bio-medicine.org/medicine-news-1/The-Oscar-Lambret-Center--28France-29-Completes-First-Stage-Of-Winscribe-Text-Rollout-147489-1/
10.1038/s41379-019-0249-1,Medicine_easy_511,Note: material may have been edited for length and content.,"HPV-negative tumors were more frequently of the non-squamous type (9/21, 43% vs. 37/193, 19%; p < 0.01) and showed negative p16 staining (9/21; 43% vs. 7/193; 4%; p < 0.01).","""The new study confirms that HPV-negative tumours represent a more aggressive type of cancer with worse prognosis, which must be considered for the clinical management of these patients,"" he adds. Note: material may have been edited for length and content. For further information, please contact the cited source.","Twenty-one out of 214 tumors (10%) were negative for HPV DNA. HPV-negative tumors were more frequently of the non-squamous type (9/21, 43% vs. 37/193, 19%; p < 0.01) and showed negative p16 staining (9/21; 43% vs. 7/193; 4%; p < 0.01). HPV-negative tumors were more frequently diagnosed at advanced FIGO stage (19/21, 91% vs. 110/193, 57%; p < 0.01) and more frequently had lymph node metastases (14/21, 67% vs. 69/193, 36%; p < 0.01).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39016732778&p=1pl&v=1&x=cbOsRpZYCVu8RgjbTeOnHg
10.1016/j.neuron.2017.09.032,Medicine_easy_513,"""We might find a way to stimulate the human brain or optimize training techniques to mitigate those deficits.""","In Figure 7A , we found that theta synchrony dropped both early (LM1, b = À0.28891, p = 0.027735, two-sided t test) and late (LM1, b = À0.27005, p = 0.015615).","""We might find a way to stimulate the human brain or optimize training techniques to mitigate those deficits."" The neural signatures could help identify changes in learning strategies that occur in diseases such as Alzheimer's, with an eye to diagnosing these diseases earlier or enhancing certain types of learning to help patients cope with the disorder, says Roman F. Loonis, a graduate student in the Miller Lab and first author of the paper. Molaison couldn't remember eating breakfast a few minutes after the meal, but he was able to learn and retain motor skills that he learned, such as tracing objects like a five-pointed star in a mirror.","This was the case. In Figure 7A , we found that theta synchrony dropped both early (LM1, b = À0.28891, p = 0.027735, two-sided t test) and late (LM1, b = À0.27005, p = 0.015615). In other words, we did not see any difference in the change in theta synchrony before and after learning, like we did for alpha-2/beta-1.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/w-hfqFowFj8/
10.1001/jamacardio.2018.2866,Medicine_easy_515,"Akcea plans to use the upfront payment to settle a $125 million obligation to Ionis in Akcea common stock, the companies said.",the triglyceride-lowering allele for LPL variants or the LDL-C lowering allele for the 58 LDL-C associated variants) for the effect on the respective lipid trait expressed in standardised units.,"""We believe that our deep expertise in cardiovascular and metabolic diseases will help allow this program to reach its maximum potential for patients."" Akcea plans to use the upfront payment to settle a $125 million obligation to Ionis in Akcea common stock, the companies said. Before regulatory filing for marketing approval, Akcea has the option to participate in commercialization activities with Pfizer in the United States and certain additional markets on predefined terms and based on meeting predefined criteria.","All genetic variants satisfied these criteria: (1) were over 500 kb away from each other and had no or negligible linkage disequilibrium (R 2 < 0.01); (2) the genetic regions were associated with LDL-C levels (p < 5 x 10 -8 ) in the Global Lipids Genetics Consortium analysis of up to 188,577 individuals. the triglyceride-lowering allele for LPL variants or the LDL-C lowering allele for the 58 LDL-C associated variants) for the effect on the respective lipid trait expressed in standardised units. Because polymorphisms included in genetic scores are inherited approximately randomly at the time of conception in a process known as ""Mendelian randomisation"", 18 and inherited approximately independently of the other polymorphisms included in the genetic score, the number of lipid lowering alleles that a person inherits for each genetic score should also be random.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=40368499467&p=1pl&v=1&x=JSZ2HfjDtiFiPnSQRe8oew
10.1038/s41467-018-04227-3,Medicine_easy_518,But the nanospheres also have a natural property that is especially important to Westmeyer's team: They can take in iron atoms and process them in such a way that they remain inside the nanospheres without disrupting the cell's processes.,5e ).,"""We can thus spatially separate processes and give the cells new properties."" But the nanospheres also have a natural property that is especially important to Westmeyer's team: They can take in iron atoms and process them in such a way that they remain inside the nanospheres without disrupting the cell's processes. The iron-incorporating nanocompartments are helping us to take a big step towards this goal,"" explains Westmeyer.",5d ) indicating that in the absence of the nancompartment the imported iron was not sufficiently sequestered by the endogenous iron homeostasis machinery. 5e ). These data confirmed that either B or C are sufficient to load the nanocompartment with iron and showed that no obvious additional iron loading resulted from the presence of the Mms peptides.,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34116477623&p=1pl&v=1&x=15ixZ62UWCQkoigx-xwN7Q
10.1126/science.1261447,Medicine_easy_521,"""The resources we've generated will allow us and others to delve even deeper, and finally begin to really understand the workings of this invisible world.""",At larger scales ( Fig.,"""The finding that temperature shapes which species are present, for instance, is especially relevant in the context of climate change, but to some extent this is just the beginning,"" says Chris Bowler, a plant biologist from the French National Centre for Scientific Research. ""The resources we've generated will allow us and others to delve even deeper, and finally begin to really understand the workings of this invisible world."" They found a large spike in the nitrite levels of younger rings, but had no clue as to its cause.","The mixed layer of the young ring was deep (>250 m) compared with seasonal cycles of the mixed layer depths in the region (50 to 100 m) (Fig. At larger scales ( Fig. 4B ) ( , steep spatial gradients were observed, with fresher and colder water in the Cape Basin than in the Agulhas Current because of both lateral mixing with waters from the south and surface fluxes.",[1],Medicine,train,1.0,news,http://newsoffice.mit.edu/2015/uncovering-diverse-invisible-ocean-world-0526
10.1007/s10803-016-2729-1,Medicine_easy_522,"Worth nearly PS300,000, her project will run up until 2018.","Further, 47% of police reported that they were 'fairly knowledgeable' about ASD.","The new funding will enable her to expand her research into developing support for the challenges people with autism spectrum disorder face in other important real life contexts, in particular for job interviews and medical consultations. Worth nearly PS300,000, her project will run up until 2018. Commenting on the funding, she said: ""I'm thrilled to receive this award.","More specifically, police respondents were largely satisfied (42%) with their dealings with the ASD community; with only 21% reporting dissatisfaction (37% gave a neutral response). Further, 47% of police reported that they were 'fairly knowledgeable' about ASD. However, the possibility of a discrepancy between police self-reported competence and professional conduct in practice cannot be discounted.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/xSk6tvoBtH4/
10.1098/rsif.2013.1205,Medicine_easy_523,"As a result of this lateral friction contact, larger dirt particles are removed.","30 g 5 g Owing to the random population and position of the contaminants in each samples, the processes of adhesion recovery for two samples were never alike.","(Photograph with scanning electron microscope: Michael Rohrig, KIT)

When moving forwards, the geckos toes drag across a part of the surface. As a result of this lateral friction contact, larger dirt particles are removed. Smaller particles deposit among the setae on the sole and in the skinfolds below.","Results from the experiments in figures 4 and 5 show significant cleaning for all samples. 30 g 5 g Owing to the random population and position of the contaminants in each samples, the processes of adhesion recovery for two samples were never alike. Nevertheless, we observed a general agreement between the adhesion recovery trend for a given contaminant size regime, depending on the ratio of the particle diameter to the fibre tip diameter.",[1],Medicine,train,1.0,news,http://www.nanowerk.com/nanotechnology_news/newsid=34447.php
10.1007/s40675-017-0065-4,Medicine_easy_525,"""So, definitely a big improvement from four hours,"" she says.","Indeed, when dCBT was piloted within a UK mental health service based on the stepped care model, 59% of patients showed a reliable recovery, with 88% completing four or more sessions .","""So, definitely a big improvement from four hours,"" she says. Thesing is not alone. Nearly 100 people wrote back suggesting a range of apps, including podcasts created to put a listener to sleep.","This highlights that integrating dCBT into traditional clinical care might be a slow process in need of innovative approaches and thorough research on integration models, such as the stepped care model. Indeed, when dCBT was piloted within a UK mental health service based on the stepped care model, 59% of patients showed a reliable recovery, with 88% completing four or more sessions . It is important to consider dCBT as part of the whole spectrum of digital medicine, a rapidly developing, new field of medicine, where technologies will revolutionize how patients and health professionals interact.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37327604103&p=1pl&v=1&x=T1rdR-YWJ5homnguLqVtLg
10.1016/j.molcel.2014.02.019,Medicine_easy_528,"""Importantly, this work shows that silent locus identity is required for, but separable from, actual gene silencing,"" Pikaard said.","Two loci shown to be susceptible to such spontaneous losses of CG methylation and silencing are among the Group E loci identified in our study: At5g24240 and At4g14548 (which we call ERT9 and ERT11, respectively).","The discovery made by a 12-member all-Indiana University team of scientists led by IU biologist and biochemist Craig Pikaard provides important new insight into how plant cells know to silence a genetic locus -- that specific place on a chromosome where a gene is located -- in every successive generation. ""Importantly, this work shows that silent locus identity is required for, but separable from, actual gene silencing,"" Pikaard said. ""We've found that epigenetic inheritance is a two-step process, with the heritable specification of silent locus identity occurring before actual silencing of the locus can occur.""","However, spontaneous loss of CG methylation occurs at individual loci, resulting in the sporadic emergence of transcriptionally active epialleles Schmitz and Ecker, 2012; Schmitz et al., 2011) . Two loci shown to be susceptible to such spontaneous losses of CG methylation and silencing are among the Group E loci identified in our study: At5g24240 and At4g14548 (which we call ERT9 and ERT11, respectively). Sporadic erasure of HDA6-and MET1-dependent silent locus identity can presumably account for the emergence of stable, active epialleles at these loci.",[1],Medicine,train,1.0,news,http://www.newswise.com/articles/gene-silencing-instructions-acquired-through-molecular-memory-tags-on-chromatin
10.1126/scitranslmed.aan3879,Medicine_easy_529,"""It may even have potential for temporarily treating gunshot wounds.""","These formed shapes were also maintained at 10°C, below LCST, resulting in complete structural collapse after a few hours, consistent with the thermoresponsive trends observed (fig.","""First responders at a mass casualty incident could deploy the hydrogel while patients wait for their injuries to be completely repaired by an ocular surgeon in appropriate microsurgical facilities,"" Whalen noted. ""It could also be useful in emergency rooms in rural areas where there isn't an eye center with such capabilities nearby,"" he added. ""It may even have potential for temporarily treating gunshot wounds.""","Shape persistence and stability remained for 1 month in an aqueous environment above its LCST (Fig. These formed shapes were also maintained at 10°C, below LCST, resulting in complete structural collapse after a few hours, consistent with the thermoresponsive trends observed (fig. Our hydrogel challenges the preconception that materials held together by noncovalent forces and mostly composed of water are weak.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=32701646499&p=1pl&v=1&x=eK9q0MrjpuJALT5vetSZOg
10.1038/s41598-018-37709-x,Medicine_easy_530,People with cognitive impairment had fewer capillaries in their retina than those who did not.,"The AI platform will allow for accurate classification of participants into cognitively healthy or cognitively impaired by comparing their CGN_ICA test profile with a large dataset of many individuals with validated clinical status which the AI platform has ""learned"" from.",Weintraub thinks that lower capillary counts could help indicate the early signs of dementia. People with cognitive impairment had fewer capillaries in their retina than those who did not. That's not enough data to predict if a person is in the early stages of dementia.,"The CGN_ICA is designed to be an extremely easy to use, versatile and practical measurement tool for studies into dementias and other conditions that have an element of cognitive function, as it allows simple, sensitive and repeatable data collection of an overall score of a subject's cognitive ability. The AI platform will allow for accurate classification of participants into cognitively healthy or cognitively impaired by comparing their CGN_ICA test profile with a large dataset of many individuals with validated clinical status which the AI platform has ""learned"" from. The AI engine will have the ability to improve its accuracy over time by learning from new data points that are incorporated into its training datasets.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39669460552&p=1pl&v=1&x=_5nPswP0wchea4m11hUqkQ
10.1097/01.psy.0000170341.88395.47,Medicine_easy_532,"In some cases, even if the tears appear to have healed, they may have left nerve damage, according to Prendergast, as nerves grow slowly and may be ""stunned"" after birth.","In healthy subjects, our own research group has reported lower mean 24-hour ABP in men and women reporting high compared with intermediate or low relationship quality and those with no partnered relationship .","The effects of childbirth vary depending on what kind of labor your partner had. In some cases, even if the tears appear to have healed, they may have left nerve damage, according to Prendergast, as nerves grow slowly and may be ""stunned"" after birth. If your partner did experience tearing during labor, she might feel self-conscious about the way her vagina looks.","The quality of the marital relationship seems to play an essential role in health outcomes , with greater levels of marital dissatisfaction and discord linked to enhanced health risk . In healthy subjects, our own research group has reported lower mean 24-hour ABP in men and women reporting high compared with intermediate or low relationship quality and those with no partnered relationship . In another study of ABP at home and work, time spent with the spouse or partner was characterized by lower BP compared with times spent with others or alone .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33626619506&p=1pl&v=1&x=OTigSvsWVsrww9rX18b9rw
10.1002/nau.23116,Medicine_easy_533,"""Women experienced that the app was suitable for this kind of [pelvic floor] training since they carried their smartphones with them at all times, and the reminders helped and motivated them to perform their training regularly,"" Asklund explained.","The overall scores can be divided into severity categories (1-5 = slight, 6-12 = moderate, 13- = severe, 19-21 = very severe).","""Two thirds of the women using the app were satisfied with the treatment outcomes,"" lead author Ina Asklund, PhD, told Health in an email. ""Women experienced that the app was suitable for this kind of [pelvic floor] training since they carried their smartphones with them at all times, and the reminders helped and motivated them to perform their training regularly,"" Asklund explained. For women who'd prefer to manage their incontinence themselves, this is an option worth trying, she says: ""There are many health apps, but very few are evaluated in research studies.""","The responses summed to an overall score of 0-21, where 21 was most severe. The overall scores can be divided into severity categories (1-5 = slight, 6-12 = moderate, 13- = severe, 19-21 = very severe). The ICIQ-LUTSqol contained 19 questions that summed to an overall score of 19-76, where 76 corresponded to the highest impact on quality of life.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/this-app-might-help-treat-your-incontinence-study-says/
10.1038/s41598-017-14953-1,Medicine_easy_535,"Ultimately, reducing the transfer of antibiotic-resistance plasmids could help preserve the potency of antibiotics, contributing to an overall strategy to help improve human health, he added.","5, ).","Such molecules could one day be applied in clinics in hospitals that are hotbeds of resistance, Baron hopes. Ultimately, reducing the transfer of antibiotic-resistance plasmids could help preserve the potency of antibiotics, contributing to an overall strategy to help improve human health, he added. ""The beauty of what we are working on here is that the proteins are very similar to proteins that bacteria use to cause disease.","The molecules do not negatively impact bacterial viability and they have no effect on transfer of the unrelated plasmid RP4, suggesting that the effect is specific for pKM101 (supplementary Fig. 5, ). The DSF approach used as primary assay to screen a library of several hundred fragments can be conducted in most molecular biology laboratories since it uses a commonly available RT-PCR instrument and does not necessitate specialized high-throughput screening equipment.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/antibiotics-resistance-researchers-succeed-to-block-genes-of-resistance/
10.1073/pnas.1719666115,Medicine_easy_537,And males who cooperated well with other males may have been more successful hunters and scavengers.,"Their intake of relatively rare, high-protein/ fat foods would have substantially increased depending on the skills of their ""provisioner(s).""","The combination ""is a key difference that sets apart humans from all other species,"" Raghanti says. And males who cooperated well with other males may have been more successful hunters and scavengers. As human ancestors got better at cooperating, they shared the know-how for making tools and eventually developed language--all in a feedback loop fueled by surging levels of dopamine.","Their own search time and travel would have been substantially reduced, allowing them to intensify infant care and to more successfully avoid predators. Their intake of relatively rare, high-protein/ fat foods would have substantially increased depending on the skills of their ""provisioner(s)."" Females' choice of males with the greatest environmental awareness would be under intense selection, as would a male's capacity to carry exceptionally valuable foods for significant distances.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33063269549&p=1pl&v=1&x=GY_Ozg3nrmLLkOMikJx2og
10.1080/10408398.2016.1247252,Medicine_easy_538,"aIt doesnat seem to be something we should be overly concerned with,a she says.","In adults, coffee and tea were the biggest contributors to total caffeine intake.","It gives employees the choice to deny the sale of caffeinated beverages to anyone under the age of 16. aIt doesnat seem to be something we should be overly concerned with,a she says. The numbers vary, but they can be taken to suggest that caffeine, in moderation, is nothing to worry about.","Caffeinated soft drinks (48.9%) and tea (38.0%) were the greatest contributors to total caffeine intake in children and adolescents, whereas coffee (5.4%), and energy drinks (0.6%) only had a small contribution to daily total caffeine intake. In adults, coffee and tea were the biggest contributors to total caffeine intake. In adults, total caffeine intake ranged from 122 to 143 mg/day.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37606354782&p=1pl&v=1&x=NkCPm4nvG7M0zaIIZkj4mw
10.1177/0956797615617897,Medicine_easy_539,And the analysis of the infantsaEUR(tm) behaviour shows that when they expected a liquid they were surprised to see it blocked by the grid (or see the grid unable to penetrate the material).,"44, 16 .59].","aEURoeIf infants understand the properties of liquids, then they should be surprised when, what they think is a liquid gets trapped on a gridaEUR. And the analysis of the infantsaEUR(tm) behaviour shows that when they expected a liquid they were surprised to see it blocked by the grid (or see the grid unable to penetrate the material). Conversely, if they thought they were looking at a solid, then they were surprised when they saw it pass through the grid.","Infants who were habituated to the liquid looked an average of 6.45 s (SD = 8.56), 95% CI = [3.42, 9.49] longer at the novel events than at the familiar events, whereas infants habituated to the solid looked an average of 12.51 s (SD = 10.71) longer at the novel events than at the familiar events, 95% CI = [8. 44, 16 .59]. Although we did not predict this effect, infants may have firmer expectations about a solid's behavior than about a liquid's behavior, and thus the infants in our experiment may have been more surprised by the solidto-liquid shift than by the reverse shift.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/babies-have-a-grasp-of-the-physics-of-liquids/
10.1890/14-0684.1,Medicine_easy_540,"""Lemurs fill an important role as the gardeners for these trees.",Total area sampled per site was 18 000 m 2 .,"""Seeds away from the parent tree survive better because there's less competition among seedlings,"" Razafindratsima said. ""Lemurs fill an important role as the gardeners for these trees. By ensuring that some seeds land in spots suitable for germination and survival, they increase the ability of these trees to replace themselves""

Dunham hopes the study will contribute to growing efforts to protect lemurs, and therefore the rainforest, which has been impacted in recent years by economic and political instability.","The gap category was representative of observed recent tree-fall gaps in the park. Total area sampled per site was 18 000 m 2 . However, our germination rates for Cryptocarya seeds were similar to rates found for seeds passed through the gut of the three lemur species in a previous study .",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/11/141104083849.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/srep33746,Medicine_easy_542,"That requires further work, but it is an exciting and important possibility.""",As seen previously (Fig.,"""Through this process we were able to demonstrate how the spread of this toxicity is driven. In doing that we also uncovered a previously unknown, fast acting, neuroprotective signalling mechanism. That requires further work, but it is an exciting and important possibility.""","Spreading toxicity during stroke or a TBI in vivo is likely to be a consequence of both synaptic toxicity through hyperactivity and excitotoxicity from extracellular accumulation of glutamate 5 . As seen previously (Fig. 3a,c) , no protection was afforded to the directly preconditioned chamber (Fig.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/stimulating-neurons-could-protect-against-brain-damage-research-shows/
10.1098/rsos.150292,Medicine_easy_543,"Sheas stressed and desperate, so itas a relief when they FaceTime her asking her to acome playa while calling her aBeckalicious.a When she asks, aYou guys love me?a they respond like thatas the dumbest question in the world.","The 15-layer has likewise been widely identified, with online values varying between 11.2 and 20.9 and offline between 9.0 and 20.0 .","Lifetime

The audienceas first introduction to Beck's friends Peach, Annika, and Lynn paints them as a good support system for our weary protagonist. Sheas stressed and desperate, so itas a relief when they FaceTime her asking her to acome playa while calling her aBeckalicious.a When she asks, aYou guys love me?a they respond like thatas the dumbest question in the world. aOf coursea they love her.","Sample 1 also confirms the existence and size of the two innermost layers of the social network, now conventionally identified as the support clique and the sympathy group . The 15-layer has likewise been widely identified, with online values varying between 11.2 and 20.9 and offline between 9.0 and 20.0 . In the present sample, the mean values for these two layers (4.1 and 13.6) fit comfortably within these ranges.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38341050496&p=1pl&v=1&x=Q_UDVvb8Z9mwJ-bM3otzgg
10.1073/pnas.1313039111,Medicine_easy_544,"Lee said the players found a solution by putting the GC pairs only at the end of the stack -- ""capping"" -- and filling the rest of the stack with adenine-uracil pairs.","These results show that an online community can carry out large-scale experiments, hypothesis generation, and algorithm design to create practical advances in empirical science.","But too many GC pairs can produce some unexpected shapes when synthesized -- ""It's like doing origami with a cardboard box,"" as one player put it. Lee said the players found a solution by putting the GC pairs only at the end of the stack -- ""capping"" -- and filling the rest of the stack with adenine-uracil pairs. They also are developing a template that researchers in other fields can use to turn scientific projects into online challenges.","These rules, distilled by machine learning into a new automated algorithm EteRNABot, also significantly outperform prior algorithms in a gauntlet of independent tests. These results show that an online community can carry out large-scale experiments, hypothesis generation, and algorithm design to create practical advances in empirical science. The initial 6-mo training period, called phase I, saw the EteRNA community engaging in six RNA design problems containing increasing numbers of nonhelical elements (bulges and multihelix junctions) and more complex topologies ( Fig.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127164801.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1002/per.704,Medicine_easy_545,"However, that impulse toward convention doesn't lend itself to every job type.","A total of 731 participants met these criteria: 181 participants from the baseline assessment only, 248 participants from the follow-up assessment only, and 302 from both assessments.","While conscientiousness doesn't correlate with high SAT scores, it does predict high GPAs. However, that impulse toward convention doesn't lend itself to every job type. Work that requires innovation, creativity, and spontaneity doesn't fit well to a highly conscientious personality; a highly conscientious painter would stick to the norms of a genre rather than expanding it, and a highly conscientious chef would be less likely to tinker with tried-and-true recipes.","Finally, as young adulthood is more of a time of flux, in both personality and work life, and therefore more susceptible to outside influences, we expect the longitudinal relations to be confined primarily to younger adults. A total of 731 participants met these criteria: 181 participants from the baseline assessment only, 248 participants from the follow-up assessment only, and 302 from both assessments. Income and job satisfaction were available for a subset of these participants (income: concurrent n = 631, longitudinal n = 242; job satisfaction: concurrent n = 719, longitudinal n = 302; prestige scores were available for all participants).",[1],Medicine,train,1.0,news,http://www.businessinsider.com/conscientiousness-predicts-job-performance-2014-12
10.1038/s41540-017-0043-y,Medicine_easy_546,"""Synthetic biology is important for gene therapy applications, and our methodology may assist in building more robust and reliable therapeutics in the future,"" Bleris said.","Using Pearson's correlation, the coefficient of determination (R-Squared) values obtained from the fits for the 1, 0.1, and 0.01 ng/mL Dox concentrations were all above 0.95 where the 0.001 ng/mL Dox induced group had an R-Squared value above 0.8.","""By using principles of math and physics in synthetic biology, we uncovered specific properties of microRNA that can be used in future applications for targeted and smart therapeutics."" He also said that this research could shed light on natural genetic redundancies and other diseases where microRNA are not at physiological levels. ""Synthetic biology is important for gene therapy applications, and our methodology may assist in building more robust and reliable therapeutics in the future,"" Bleris said.","where γ is the decay constant, ω controls the rate of saturation with respect to c, which represents the plasmid copies. Using Pearson's correlation, the coefficient of determination (R-Squared) values obtained from the fits for the 1, 0.1, and 0.01 ng/mL Dox concentrations were all above 0.95 where the 0.001 ng/mL Dox induced group had an R-Squared value above 0.8. Interestingly, the decay constant γ was found to be the same at all Dox concentrations, thus attributing the differences in behavior of the repression efficiency at different Dox concentrations to variations in the parameter ω.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33490142809&p=1pl&v=1&x=7kV89J9ospqm2Qxx1MsxLg
10.1186/s12929-018-0404-x,Medicine_easy_547,Dr. Schneider says that regular activity doesnat necessarily mean you have to start hitting the gym every day.,"In aged rats and primates, BDNF infusion produced beneficial effects on age-related perturbations in gene expression and ameliorated agerelated cognitive impairment .","By cutting down on smoking, you could be doing your a huge favor for your cognitive health down the road. Dr. Schneider says that regular activity doesnat necessarily mean you have to start hitting the gym every day. He said you should aim for a least a few walks a week, and try to keep up an active lifestyle in general.","Reduced protein and mRNA levels of BDNF were found in the hippocampus of postmortem AD samples and MCI patients, . In aged rats and primates, BDNF infusion produced beneficial effects on age-related perturbations in gene expression and ameliorated agerelated cognitive impairment . Indeed, the results showed that APP/PS1 mice performed better in memory tasks if their companies interacted with them more often.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39395405146&p=1pl&v=1&x=jVK2N5h6x8DoIkfbCSzsUA
10.1073/pnas.1720487115,Medicine_easy_548,"Those mutational differences often emerged even among closely related species residing on the same plateau, the study reported.",Evolutionary increases in Hb-O 2 affinity may be caused by amino acid mutations that increase the intrinsic O 2 affinity of the Hb tetramer and/or mutations that suppress the sensitivity of Hb to the affinity-reducing effects of allosteric cofactors (nonheme ligands such as Cl − ions and organic phosphates) .,"Those mutational differences often emerged even among closely related species residing on the same plateau, the study reported. ""You could imagine, just because of the different ancestral starting points, that the Tibetan birds maybe all went one (mutational) route, and the Andean birds typically did things a different way,"" said co-author Jay Storz, Susan J. Rosowski Professor of Biological Sciences at Nebraska. ""But that's not what we saw.","Under severe hypoxia, an increased Hb-O 2 affinity safeguards arterial O 2 saturation, thereby securing tissue oxygenation, albeit at a lower pressure gradient for O 2 diffusion from the peripheral capillaries to the cells of respiring tissues . Evolutionary increases in Hb-O 2 affinity may be caused by amino acid mutations that increase the intrinsic O 2 affinity of the Hb tetramer and/or mutations that suppress the sensitivity of Hb to the affinity-reducing effects of allosteric cofactors (nonheme ligands such as Cl − ions and organic phosphates) . If such contingencies influence the adaptive evolution of Hb function, such that highland representatives of different lineages hit upon different solutions to the same problem, this may be reflected in clade-specific or regionspecific patterns of molecular parallelism.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/0IiwEKtJQjU/
10.1016/j.biopsych.2013.05.025,Medicine_easy_549,"""The stranger anxiety or wariness that young children typically show is a sign that they understand their parents are very special people who are their source of security.""",e n ¼ 2 missing data from PI group.,"""The stranger anxiety or wariness that young children typically show is a sign that they understand their parents are very special people who are their source of security."" The UCLA researchers discovered that while the typically-raised children exhibited higher amygdala signals for their mothers compared to strangers, the previously institutionalized children showed amygdala responses to strangers that were similar to those they showed toward their adoptive mothers. Additionally, the children who had lived in an institution showed greater amygdala reactivity to strangers than did the typically-raised children.",d n ¼ 8 missing data from Comp group. e n ¼ 2 missing data from PI group. f n ¼ 1 missing data from PI group.,[1],Medicine,train,1.0,news,http://www.medicaldaily.com/neglected-babies-may-develop-dangerous-indiscriminate-friendliness-childhood-along-changes-brain
10.1186/gb-2014-15-2-r27,Medicine_easy_550,Charles Wondji said: 'We found a population of mosquitoes fully resistant to DDT (no mortality when they were treated with DDT) but also to pyrethroids.,Peaks were detected at 232 nm.,"The authors say that knowing how resistance works will help to develop tests, and stop these genes from spreading amongst mosquito populations. Charles Wondji said: 'We found a population of mosquitoes fully resistant to DDT (no mortality when they were treated with DDT) but also to pyrethroids. They identified the GSTe2 gene as being upregulated - producing a lot of protein - in Benin mosquitoes.",All constructs yielded 26.8 kDa products. Peaks were detected at 232 nm. Preliminary crystallization conditions led to crystal clusters of thin plates.,[1],Medicine,train,1.0,news,http://www.healthcanal.com/infections/47991-researchers-at-lstm-crack-the-genetic-secret-of-mosquito-resistance-to-ddt-and-bed-net-insecticides.html
10.1242/jeb.098301,Medicine_easy_551,"Surprisingly, female ants are the ones who demonstrate this macho behavior.",Negative control (without reverse transcriptase) and melting curve analyses confirmed that the qRT-PCR analysis was not confounded by DNA contamination or primer dimers.,"Surprisingly, female ants are the ones who demonstrate this macho behavior. ""The answer appears to be dopamine. We found that gamergates have dopamine levels two to three times higher than other workers.""","Pooling brain samples within colonies was necessary to get measurable levels of biogenic amines but it does decrease resolution with respect to individual brain amine levels. Negative control (without reverse transcriptase) and melting curve analyses confirmed that the qRT-PCR analysis was not confounded by DNA contamination or primer dimers. We included gamergates from seven additional colonies in this study (20 colonies total), and with this larger sample size all variables conformed to the assumption of normality required for regression analyses.",[1],Medicine,train,1.0,news,http://www.natureworldnews.com/articles/7008/20140512/dopamine-turns-worker-ants-into-warrior-queens.htm
10.1186/s12915-018-0524-5,Medicine_easy_552,"""It's not unlike seeing a bicycle being pedaled: You get more than a static picture and a better understanding of how it works.","It appears, however, that at the very high concentrations of CEF applied here (around 200 mmol/L), stacking is not required for effective catalysis, as the kinetics in the monomeric needles, where stacking does not occur, is similar to that in the shard crystal form.","""This will teach us more about how nature has selected for and designed these molecules to work,"" he said. ""It's not unlike seeing a bicycle being pedaled: You get more than a static picture and a better understanding of how it works. ""Anytime you want to engineer a protein or recreate a molecular machine, knowing more about how they work at a fundamental level is going to be helpful, whether it's breaking down cellulose for biofuels or designing a new drug or improving an existing drug.""","However, the binding of the additional CEF molecule could be a mechanism to steer the substrate towards, and orient it with respect to, the active site under certain conditions. It appears, however, that at the very high concentrations of CEF applied here (around 200 mmol/L), stacking is not required for effective catalysis, as the kinetics in the monomeric needles, where stacking does not occur, is similar to that in the shard crystal form. When only low CEF concentrations are present, stacking might well be essential to recruit antibiotic substrate molecules to promote effective BlaC function.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34227031048&p=1pl&v=1&x=lbeh9QknwsyjFW3nEb3T4Q
10.1111/j.1749-6632.2012.06538.x,Medicine_easy_553,"His 2 Week Diet also:

lCorrects common misconceptions popularized by the mainstream dieting industry

lProvides dieters with a straightforward, step-by-step plan of action

Produces rapid results to fuel dieter motivation avoids outdated and ineffective techniques like ""Count every calorie"" and the ""Eat less, exercise more"" mantra.",Only 4% (4/97) of controls had zonulin levels 2 SD above the mean (P < 0.01).,"SOURCE: Dr. Fasano Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384703/



""If we take control of cellular inflammation, we can effectively increase our ability to lose weight, burn fat, increase metabolism, and permanently stave off body fat,"" Flatt said. His 2 Week Diet also:

lCorrects common misconceptions popularized by the mainstream dieting industry

lProvides dieters with a straightforward, step-by-step plan of action

Produces rapid results to fuel dieter motivation avoids outdated and ineffective techniques like ""Count every calorie"" and the ""Eat less, exercise more"" mantra. ""It's true that eating certain foods and following rigorous workout programs will produce weight loss.",Forty-two percent (141/339) of T1D patients and 29% of their first-degree relatives (26/89) had serum zonulin levels that were 2 SD above the mean zonulin levels detected in age-matched healthy controls. Only 4% (4/97) of controls had zonulin levels 2 SD above the mean (P < 0.01). Serum zonulin was higher in T1D as compared to their relatives (P = 0.01).,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33868436087&p=1pl&v=1&x=DGr_SOV1N3U402PHXaTl9Q
10.1186/s40168-016-0167-0,Medicine_easy_554,"""As a young scholar at the beginning of my career, I am privileged to work with a scientist who is open-minded to new ideas and has an unquenchable passion for his work.""",We conclude that it is critical to compare the microbiome of habitat without human occupation to habitat with human occupation since humans appeared to be the primary source of contamination in such habitats.,"""The biggest assets for my career, to be where I am right now, are my students and postdocs,"" he said. ""Dr. Venkat showed me and other members of our group that teamwork and collaboration are very crucial while doing research,"" said Aleksandra Checinska, a postdoctoral scholar at JPL through Caltech in Pasadena, which manages JPL for NASA. ""As a young scholar at the beginning of my career, I am privileged to work with a scientist who is open-minded to new ideas and has an unquenchable passion for his work.""","Furthermore, the MARS 500 microbial analysis did not contain control, i.e., preoccupation bacterial diversity measurements, to compare the microbial accumulation as measured in this study. We conclude that it is critical to compare the microbiome of habitat without human occupation to habitat with human occupation since humans appeared to be the primary source of contamination in such habitats. Such a comparison may enable development of cleaning and maintenance protocols.",[1],Medicine,train,1.0,news,http://www.spacedaily.com/reports/Microbes_in_Space_JPL_Researcher_Explores_Tiny_Life_999.html
10.1093/sysbio/syx064,Medicine_easy_557,the K-Pg event) led to an acceleration in the rate of genetic evolution among its avian survivors.,"On the left, the red curve indicates a normal distribution fit to the body size distribution of the LM assemblage.","the K-Pg event) led to an acceleration in the rate of genetic evolution among its avian survivors. These survivors may have been much smaller than their pre-extinction relatives. ""All of the new evidence we have reviewed is also consistent with a Lilliput Effect affecting birds across the K-Pg mass extinction.""","The depicted progression of body size reduction represents an improvement of up to 36 AICM units relative to a model that constrains the three deepest nodes to the mean LM estimate ( AICM A-B ∼36). On the left, the red curve indicates a normal distribution fit to the body size distribution of the LM assemblage. The latter two models accommodate rapid character evolution near the clade MRCA, followed by a linear or exponential decrease in the rate of evolution.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/q6b3I3XpwRc/
10.1038/s41586-018-0347-0,Medicine_easy_558,This is important not only for juicing up smartphones and laptops.,"Any Methods, including any statements of data availability and Nature Research reporting summaries, along with any additional references and Source Data files, are available in the online version of the paper at https://doi.org/10.1038/s416-018-0347-0.","This is important not only for juicing up smartphones and laptops. It could help the environment too. You get a lot more unwanted chemical reactions with the electrolyte, so the battery doesn't last as long.","These criteria, which lead to extremely high power and energy densities (Fig. Any Methods, including any statements of data availability and Nature Research reporting summaries, along with any additional references and Source Data files, are available in the online version of the paper at https://doi.org/10.1038/s416-018-0347-0. 1, Supplementary Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34640963107&p=1pl&v=1&x=go9GPx4dYbjzgyOgK56GFA
10.1038/s41467-018-07425-1,Medicine_easy_559,A high level of STING pathway activity was also detected in the lung tissue of patients with pulmonary fibrosis.,"12b ), we could show that silica-induced activation of the STING pathway, including STING dimerization and phosphorylation of TBK1 and IRF3, was partly reduced after knockdown of IFI204 and more importantly after DDX41 knockdown ( Supplementary Fig.","They also demonstrated that treatment with DNase I, an enzyme that degrades the DNA released into the airways, prevents silica-induced lung inflammation. A high level of STING pathway activity was also detected in the lung tissue of patients with pulmonary fibrosis. Thus the mechanism discovered in mice exposed to silica seems to also play a role in humans.","Among DNA sensors activating STING, IFI204, the mouse ortholog of human IFI16, and the helicase DDX41 genes were overexpressed in silica-exposed macrophages (Supplementary Fig. 12b ), we could show that silica-induced activation of the STING pathway, including STING dimerization and phosphorylation of TBK1 and IRF3, was partly reduced after knockdown of IFI204 and more importantly after DDX41 knockdown ( Supplementary Fig. 12c ), as were TNF, CXCL10, and type I IFN expression (Supplementary Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37918696723&p=1pl&v=1&x=7CLKPsENyn8kIUGN0lZgIw
10.1038/s41586-019-0969-x,Medicine_easy_560,They were able to study about 80 percent of cells in the earliest embryos and between 3 and 20 percent in the slightly older embryos.,"That is, when the nodes are close in (Euclidean) UMAP space, but distant in the graph, they should be linked.","Their analysis didn't capture every single cell in these embryos, but from the researchers' estimates, they got pretty close in some of the developmental stages. They were able to study about 80 percent of cells in the earliest embryos and between 3 and 20 percent in the slightly older embryos. This work is very different from classical methods of studying developmental biology, where researchers would mutate a single gene or a few genes and see what structures changed in the resulting developing animals.","The third major enhancement is that Monocle 3 can learn principal graphs with loops instead of requiring that the trajectory be a tree. That is, when the nodes are close in (Euclidean) UMAP space, but distant in the graph, they should be linked. The principal graph offers users a means of selecting subsets of cells that lead to particular lineages for further analysis.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38634737107&p=1pl&v=1&x=YBRHorf_ThIV1ZkEmYn25A
10.1038/ijo.2008.130,Medicine_easy_561,"From the surprisingly long list of nutrients that eggs contain to the extra health benefits that they can provide, there's a lot to love about what eggs can do for you--and how they can help you transform your body.",This lack of intensity is reflected in relatively modest weight loss in 8 weeks in the ED and BD groups.,"From the surprisingly long list of nutrients that eggs contain to the extra health benefits that they can provide, there's a lot to love about what eggs can do for you--and how they can help you transform your body. Eggs Provide 'Good' Cholesterol

Chances are, if you've ever spoken to an advocate of decreased egg consumption, you've heard about the dangers of all the cholesterol they contain. The individuals saw their ""good"" cholesterol (which builds healthy cells and helps the body produce certain hormones) go up after a few weeks of eating multiple eggs a day.","However, eating an egg breakfast while on a reduced energy diet does enhance weight loss. This lack of intensity is reflected in relatively modest weight loss in 8 weeks in the ED and BD groups. Despite the modest weight loss, the results suggest that much better weight loss is possible if the reduction in energy intake, the most common weight loss approach in the United States, is supplemented by an egg breakfast.",[1],Medicine,train,1.0,news,https://www.theepochtimes.com/what-happens-to-your-body-if-you-eat-2-eggs-a-day-is-it-really-as-bad-as-they-say_2978632.html
10.1098/rspb.2018.2194,Medicine_easy_562,"When scientists exposed frogs from quiet ponds to the noises of a busy highway, the amphibians became stressed.",).,"New analysis of frogs from noisy and quiet ponds revealed two different stress and immune profiles. When scientists exposed frogs from quiet ponds to the noises of a busy highway, the amphibians became stressed. In addition to producing more of the stress hormone corticosterone, the frogs also experienced changes to their immune profile.","Additionally, the reduced mass gain over the exposure period may be a response to the cost of maintaining elevated CORT and could impact survival through compromised immune function. ). We provide evidence of the consequences of traffic noise on two fitness-relevant aspects of the innate immune response in a non-human vertebrate.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37757331967&p=1pl&v=1&x=Ic-ANo1XSnsnwmMF4BCyUg
10.1038/s41564-018-0222-7,Medicine_easy_563,"The researchers found this same channel through the membrane also serves an unexpected second function, providing a pathway for smaller molecules, such as waste and nutrients, to pass in and out of the parasite.","A full channel conductance (~300 pS) can be estimated from stepwise decrements in conductance (presumably channels diffusing out of the patch, Supplementary Fig.","The researchers found this same channel through the membrane also serves an unexpected second function, providing a pathway for smaller molecules, such as waste and nutrients, to pass in and out of the parasite. Beck said that dual function means this pathway plays an especially critical role for the parasite, making it a potential target for new therapies. ""Understanding the structure and function of PTEX can give us clues about how to design new drugs,"" he said.","6 ), consistent with sub-conductance states described previously for the PVM when scaling conductance for ion concentration . A full channel conductance (~300 pS) can be estimated from stepwise decrements in conductance (presumably channels diffusing out of the patch, Supplementary Fig. The G-V response was maximal near zero transmembrane potential and diminished with both positive and negative voltages (V half-open, positive = 2 ± 2 mV and V half-open, negative = − 63 ± 2 mV), also consistent with previous reports , .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34929102508&p=1pl&v=1&x=mpGPejlKTQcUHYHeNaqMiA
10.1038/s41598-017-14471-0,Medicine_easy_564,"""The biggest gut wrench is that we have starving orcas.","Nevertheless, even when data on certain aspects of the population or its threats are not available, we can use PVA models to explore possible outcomes across a plausible range of values, and thereby identify which factors might be important and the target of additional research.","But with so many other local fish possibilities, it just felt wrong to take chinook out of orcas' mouths, she said. ""The biggest gut wrench is that we have starving orcas. That depletes the food supply for orcas in their primary foraging areas.Seeing the impact on the whales, declined to only 75 members in the J, K and L pods, just became too much, Erickson said.She said hers was a decision borne of personal reflection.","PVA can be a powerful tool for informing management and conservation decisions. Nevertheless, even when data on certain aspects of the population or its threats are not available, we can use PVA models to explore possible outcomes across a plausible range of values, and thereby identify which factors might be important and the target of additional research. The Baseline model projects mean population growth over the next 100 years of r = −0.002, with variation across years of SD = 0.045 ( Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34932960007&p=1pl&v=1&x=eDTI_JU64jpqK9Rrut3DpA
10.1073/pnas.1601040113,Medicine_easy_566,"This supernova was so close to our planet that, depending on where it went off, our evolutionary ancestors might have seen it as a bright light in the sky.","In particular, surface normalized bacterial Fe-reducing reaction rates are ∼ 1.5 − 2 orders faster for nano-sized ferrihydrite particles as compared to grains with sizes comparable to bulk detrital grains.","This supernova was so close to our planet that, depending on where it went off, our evolutionary ancestors might have seen it as a bright light in the sky. As our solar system traveled through radioactive specks of stardust left over from the explosion, some of the dust broke through our atmosphere and rained down on our planet. That's because the type of ocean crust they found the debris in grows extremely slowly -- about 1 millimeter every million years.","The Fe uptake capability of DMRB from particulate sources depends on the type of source mineral and particle size. In particular, surface normalized bacterial Fe-reducing reaction rates are ∼ 1.5 − 2 orders faster for nano-sized ferrihydrite particles as compared to grains with sizes comparable to bulk detrital grains. MTB are therefore able to take up ferric and ferrous iron from various sources with similar capabilities as for DMRB.",[1],Medicine,train,1.0,news,http://www.businessinsider.com/stardust-ocean-radioactive-cosmic-supernova-explosion-pnas-2016-8
10.1542/peds.2007-1894,Medicine_easy_567,Testing this would take around five to seven years and require a sample of several thousand men.,"However, a high melanin concentration can cause decreased vitamin D synthesis by preventing UV-B from reaching the stratum basale and spinosum of the epidermis, and this risk becomes manifest in situations of inadequate sun exposure.","For vitamin D to successfully become a biomarker, research would need to prove that the test is safe, consistent, and a provable substitute for clinical endpoint. Testing this would take around five to seven years and require a sample of several thousand men. But lest this research prompts you to go on a sunbathing binge to increase your vitamin D levels, just remember to lather up with sunscreen: Men are more likely to get skin cancer than tumors on their prostate.","Therefore, it imparts an evolutionary advantage to dark-skinned people who live in areas of excessive sun exposure. However, a high melanin concentration can cause decreased vitamin D synthesis by preventing UV-B from reaching the stratum basale and spinosum of the epidermis, and this risk becomes manifest in situations of inadequate sun exposure. It is important to note that women of all populations have lighter skin than men, presumably because of increased vitamin D and calcium needs during pregnancy and lactation.",[1],Medicine,train,1.0,news,http://qz.com/204932/vitamin-d-may-be-key-to-why-black-men-get-more-deadly-prostate-cancers/
10.1038/s41588-018-0127-7,Medicine_easy_568,The causes are both genetic and environmental.,101 ).,"This is particularly worrying for severely short-sighted people as it increases their risk of developing eyesight complications. The causes are both genetic and environmental. The study established 161 genetic factors for spherical equivalent and myopia, most of which were previously unknown.","2b) , and thus weighting by (1/√ n effective ) yielded a final weighting ratio of 1:1 (ref. 101 ). 102 ).",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34316372542&p=1pl&v=1&x=olHMEPNk-t2Lx_dOjLqTiQ
10.1177/0956797612459659,Medicine_easy_569,"But itas never too late to begin, right?","In principle, the strongest evidence for enhanced cognitive ability is therefore derived from studies that use a training task with little resemblance to the outcome measure.","And if youare wondering how often you need to meditate to have an improved sex life, that aspect was not covered in this study. But itas never too late to begin, right? aIt is difficult to be fully present and aroused if we have a abusya mind and are thinking of everything we need to get done that day, for example.","Given that the default network has been repeatedly associated with markers of mind wandering , future research should directly test whether mindfulness training reduces mind wandering by dampening activation of the default network. In principle, the strongest evidence for enhanced cognitive ability is therefore derived from studies that use a training task with little resemblance to the outcome measure. From this perspective, our use of mindfulness training in the present investigation allowed us to provide a rigorous demonstration of cognitive enhancement that cannot be attributed to overlap between training and testing contexts.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33634494848&p=1pl&v=1&x=ozfUlstw5uB_7vK6OrhHsg
10.1016/j.cell.2017.01.041,Medicine_easy_570,"""It's possible that such a strategy could also improve the effectiveness of other drugs, such as those that need to reach the brain.""",Superposition of each of the two rigid bodies from the apo and LTC 4 -bound forms yields Ca RMSD values of <1 Å ( Figure S5 ).,"Since other members of this family also eject drugs, this work has medical relevance beyond MRP1. ""Ultimately, we hope these and other structures like them could serve as templates for designing chemotherapy drugs the pumps don't recognize, or inhibitors that block them,"" Johnson says. ""It's possible that such a strategy could also improve the effectiveness of other drugs, such as those that need to reach the brain.""","As LTC 4 binds at the interface of the two TM bundles, it serves as a connecting bridge to bring the two halves of the transporter closer together. Superposition of each of the two rigid bodies from the apo and LTC 4 -bound forms yields Ca RMSD values of <1 Å ( Figure S5 ). Several residues, including W553, N1244, W1245, and R1248, reposition their side chains to form proper interactions with LTC 4 ( Figure 6B ; Movie S2).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/researchers-shed-new-light-on-molecular-pump-that-ejects-anticancer-agents/
10.1111/apt.14062,Medicine_easy_571,The findings suggest that regular yoga may be a valuable adjunct to conventional medical therapies for ulcerative colitis.,Additional Supporting Information may be found in the online version of this article:,"The findings suggest that regular yoga may be a valuable adjunct to conventional medical therapies for ulcerative colitis. Our study suggests that it might be worthwhile to consider yoga as part of a multimodal integrative approach for treating ulcerative colitis,"" said Prof. Holger Cramer, lead author of the Alimentary Pharmacology Therapeutics study.","Yoga can thus be discussed as a safe, acceptable and effective ancillary intervention for patients with ulcerative colitis and impaired quality of life. Additional Supporting Information may be found in the online version of this article: Bold P-values indicate significant group differences (P < 0.05).",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/yoga-helps-patients-with-ulcerative-colitis/
10.1038/s41467-018-05635-1,Medicine_easy_572,"That's the bottom line,"" Mahowald said.",3) 54 .,"Both of these studies add nuances to how effective reducing black carbon to improve air quality and reduce climate change will be, according to Natalie Mahowald, the Irving Porter Church Professor of Engineering and Atkinson Center for a Sustainable Future faculty director for the environment, who coauthored the particle-size paper. ""We really need to understand more about preindustrial fires and how we're changing the size distribution of the black carbon emissions. That's the bottom line,"" Mahowald said.",2 and Supplementary Fig. 3) 54 . A reevaluation of the role of BC in the Earth system using aerosol models which can resolve many MS categories is therefore needed.,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=37286573745&p=1pl&v=1&x=9uoyBPo_0Au4jjyO_XQmjQ
10.1038/s41598-019-39913-9,Medicine_easy_573,"Forskerne bak den lille studien undersokte potensielle effekter av DEHP, en kjemikalie som brukes til a lage plast og finnes i elementer som mobler, gulv, tepper, polstring, leker og sko.","In this latter study, all data was generated from a single laboratory using consistent techniques and thus did not suffer from changes in methodology and quality assurance over the time span encompassed in human meta-analytical studies 9 .","Hunder kan lide av det samme problemet. Forskerne bak den lille studien undersokte potensielle effekter av DEHP, en kjemikalie som brukes til a lage plast og finnes i elementer som mobler, gulv, tepper, polstring, leker og sko. De testet ogsa polyklorert bifenyl 153: den forbudte kjemikalien som finnes i miljoet og har vaert knyttet til mannlig infertilitet.","Temporal trends in human semen quality are paralleled by a similar trend in dogs that live in the human household, where sperm motility declined by 30% over a 26 year period 8 . In this latter study, all data was generated from a single laboratory using consistent techniques and thus did not suffer from changes in methodology and quality assurance over the time span encompassed in human meta-analytical studies 9 . These observations support the hypothesis that temporal trends in semen quality, both in the human and dog, are due to shared environmental factors and that the dog may be a sentinel for human exposure to such factors.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39570151736&p=1pl&v=1&x=SssV8yn22msPHOIzUiXRWg
10.1126/scitranslmed.aaa5843,Medicine_easy_574,It also enhances the ability of the heart to respond to changes brought about by ageing.,"*P < 0.05, **P < 0.01, ***P < 0.001, N.S.","This suggests that as individuals grow old, the vinculin in the body rises in order to keep the heart pumping. The insects lived 150 percent longer compared to their normal lifespan. It also enhances the ability of the heart to respond to changes brought about by ageing.","In such models, a relationship between cardiac vinculin expression and clinically relevant functional metrics (pressure-volume relationship, ejection fraction, or In (C) to (E), *P < 0.05, **P < 0.01, compared to control by one-way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001, N.S. **P < 0.01, ***P < 10 −6 for population over time versus control, two-way ANOVA.",[1],Medicine,train,1.0,news,http://www.techtimes.com/articles/61556/20150618/the-secret-to-a-young-and-healthy-heart-researchers-identify-heart-repair-protein.htm
10.2134/jeq2014.12.0540,Medicine_easy_576,"We have to remember that those ponds wouldn't be there without the beavers.""","Across all sites and seasons, average dry bulk density was 0.33 g cm -3 .","With their return they help solve one of the major problems of the 21st century. I don't want to minimize that. We have to remember that those ponds wouldn't be there without the beavers.""","Percentage soil moisture within the soil cores ranged from 70 to 90%, with an average of 79%. Across all sites and seasons, average dry bulk density was 0.33 g cm -3 . Pond C had slightly more acidic soil with a soil pH of 5.5, compared with 6.3 and 6.0 in Ponds A and B, respectively.",[1],Medicine,train,1.0,news,http://www.terradaily.com/reports/Beavers_take_a_chunk_out_of_nitrogen_in_Northeast_rivers_999.html
10.1007/s40264-014-0155-x,Medicine_easy_577,i so dont miss the dreams i had when i was on zoloft -- hayleejean.,Conclusion Patients reporting AEs on Twitter showed a range of sophistication when describing their experience.,"These scientists believe these posts have the potential to quickly warn pharmaceutical companies of potential drug reactions. i so dont miss the dreams i had when i was on zoloft -- hayleejean. ""For example, a psychiatrist can't see suicidal ideation as an ADR while a patient can describe it perfectly.""","Similar overall distribution profiles were observed, with Spearman rank correlation rho of 0.75 (p \ 0.0001) between Proto-AEs reported in Twitter and FAERS by SOC. Conclusion Patients reporting AEs on Twitter showed a range of sophistication when describing their experience. Additional work is needed to improve data acquisition and automation.",[1],Medicine,train,1.0,news,http://www.inquisitr.com/1914900/up-to-90-percent-of-adverse-reactions-unreported-pharma-companies-search-social-media-to-make-drugs-safer/
10.1016/j.neuron.2014.08.013,Medicine_easy_578,"The surprising result: ""We found that in more than half of the cells, the axon does not emerge from the cell body, but arises from a lower dendrite,"" Thome says.","For all data, *p < 0.05, **p < 0.01, and ***p < 0.001; ns, not significant.","The surprising result: ""We found that in more than half of the cells, the axon does not emerge from the cell body, but arises from a lower dendrite,"" Thome says. ""Our measurements indicate that dendrites that are directly connected to the axon, actively propagate even small input stimuli and activate the neuron,"" says second first author Tony Kelly, a member of the Sonderforschungsbereich (SFB) 1089 at the University of Bonn. A computer simulation of the scientists predicts that this effect is particularly pronounced when the information flow from other dendrites to the axon is suppressed by inhibitory input signals at the cell body.","Higher current injection results in steeper depolarization and typically yields lower action potential thresholds. For all data, *p < 0.05, **p < 0.01, and ***p < 0.001; ns, not significant. Supplemental Information includes eight figures, one table, and three movies and can be found with this article online at http://dx.doi.org/10.1016/j.neuron.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2014/09/140922091116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.pcad.2017.03.005,Medicine_easy_579,He sees it particularly around the eyes or crow's feet (likely because of squinting).,"Nevertheless, life expectancy is a metric that is easy to understand and could convey a powerful public health message.","""I do find that my patients who are in the gym or running every day and have great metabolisms--their Botox wears off a little more quickly,"" explains Anolik. He sees it particularly around the eyes or crow's feet (likely because of squinting). Engelman also sees this amongst her active and health-conscious patients.","However, because walking is usually safer and easier to start and sustain, the choice between running and walking should be made not only based on time efficiency, but also individual lifestyle, CRF level, health conditions, and personal preferences. Nevertheless, life expectancy is a metric that is easy to understand and could convey a powerful public health message. We found that runners had a 3.2 years longer life expectancy, compared with non-runners, based on a survival analysis from the ACLS cohort.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39403921692&p=1pl&v=1&x=AB9wNeP9Ym99ZqGW0Wn8CA
10.1038/s41598-017-08106-7,Medicine_easy_580,"---

Image credit: Paul Kozowyk

Comments

comments",Chemical and microscopic analysis of experimental material alongside archaeological remains may help illuminate which methods were likely used in the past by understanding the formation and thermal degradation of biomarkers (cf.,"aIt's possible that all three methods we tested, or even some different methods, were used depending on the needs or requirements at the time... My personal favorite is the pit roll method, because it's simple, but still produced reasonable quantities ofA tar,a Kozowyk said in an interview with Seeker. While tar was eventually used for many purposes, he added, it is aunlikelya that the Neanderthals used it for anything other than tool fabrication. ---

Image credit: Paul Kozowyk

Comments

comments","However, the tar lumps themselves may be able to give further insights into the evolution of the technique used. Chemical and microscopic analysis of experimental material alongside archaeological remains may help illuminate which methods were likely used in the past by understanding the formation and thermal degradation of biomarkers (cf. While there are many potential methods of producing tar 26 , we have demonstrated that there are at least three successful aceramic solutions, ranging from low to high-tech.",[1],Medicine,train,1.0,news,http://www.redorbit.com/news/science/1113418691/researchers-reveal-how-neanderthals-made-the-first-glue/
10.3945/jn.109.116640,Medicine_easy_582,"She shared what worked so well for her with the masses, and the Instagrammable hashtag #Whole30, which to date has spawned 3.4 million posts, was born.","Notwithstanding, the current findings of strong relationships between both whole and refined grain intakes and PAI-1 and the opposing directionality of these associations suggest that the grain variables used in this study adequately differentiated between high and low whole and refined grain consumers, as any misclassification error would have likely been nondifferential and would have tended to bias results toward the null.","She shared what worked so well for her with the masses, and the Instagrammable hashtag #Whole30, which to date has spawned 3.4 million posts, was born. Whole30 involves a lot of diet restriction and willpower, which means the diet may not be the right choice for everyone. In fact, it ranked near the bottom of the list of US News & World Report's 40 best diets of 2018.","The FFQ used in this analysis was limited in its ability to accurately classify whole and refined grain intakes due to lack of specificity of some of the FFQ item lines, as the FFQ was not designed to distinguish between whole and refined grain intakes. Notwithstanding, the current findings of strong relationships between both whole and refined grain intakes and PAI-1 and the opposing directionality of these associations suggest that the grain variables used in this study adequately differentiated between high and low whole and refined grain consumers, as any misclassification error would have likely been nondifferential and would have tended to bias results toward the null. One strength of the FFQ used was that it was modified to include food items that were reported to be regularly consumed by Hispanic and African American residents in the study center areas, which was especially important for measuring grain intakes in ethnic groups, as the foods added to the questionnaire included refined grain products (e.g.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33565657540&p=1pl&v=1&x=rLxgMmzaSOmWVxthTYB20w
10.1002/oby.21538,Medicine_easy_583,"""And it's something that never has a finish line.","The magnitude of metabolic adaptation increased 6 years after ""The Biggest Loser"" competition.","""I think that weight loss is super controversial,"" said Harper. ""And it's something that never has a finish line. Which he sees as more of a constant challenge than a problem.","These observations suggest that metabolic adaptation is a proportional, but incomplete, response to contemporaneous efforts to reduce body weight from its defended baseline or ""set point"" value . The magnitude of metabolic adaptation increased 6 years after ""The Biggest Loser"" competition. This was surprising given the relative stability of body weight before the follow-up measurements compared with the substantial negative energy balance at the end of the competition which is known to further suppress RMR .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39890159927&p=1pl&v=1&x=d6KHMAJ56IU315rdfcpknw
10.1098/rspb.2017.1870,Medicine_easy_584,"The researches found that people in a higher social class ""consistently related to lower levels of wise reasoning,"" the authors wrote in their paper.",¼ 0.003).,"Affluent people have more resources available to them, and their status might suggest they've made smart decisions about money. The researches found that people in a higher social class ""consistently related to lower levels of wise reasoning,"" the authors wrote in their paper. The results were consistent across different regions of the United States and occurred regardless of people's IQ, age, gender and personality differences in agreeableness, openness to new experiences and consideration of others' emotions.","¼ 0.013) as compared to the between-state level (s.e. ¼ 0.003). As figure 1 indicates, people from states with higher average social class were less likely to use wise reasoning style about interpersonal experiences from their lives as compared to people from states with lower average social class, r ¼ 20.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=32924247950&p=1pl&v=1&x=r1C2CMK8np2z8Gd9NKhSdw
10.1038/nature12686,Medicine_easy_585,"The group plans to make technology, and all the data, available to the broader research community -- -which is especially helpful now that great ape research is severely restricted in the United States and abroad -- -so that other scientists can learn about primates using non-invasive, ethically sound methods.",The reduced levels of A3B in NHP iPS cell were not due to an A3B deletion polymorphism previously described in human individuals 34 (data not shown).,"""It could mean that we have gone, as humans, through one or more bottlenecks in evolution, that decrease the variability present in our genome,"" says Marchetto, though the hypothesis is admittedly hard to prove. The new study provides proof of concept that the iPSC technology can be used to understand some of the evolutionary differences between humans and non-human primates, says Narvaiza. The group plans to make technology, and all the data, available to the broader research community -- -which is especially helpful now that great ape research is severely restricted in the United States and abroad -- -so that other scientists can learn about primates using non-invasive, ethically sound methods.","Relative A3B and PIWIL2 mRNA levels normalized to GAPDH for each individual iPS cell line and fibroblasts are shown in Extended Data Fig. The reduced levels of A3B in NHP iPS cell were not due to an A3B deletion polymorphism previously described in human individuals 34 (data not shown). At this time after transfection, eGFP RNA expressed from retrotransposed L1-eGFP will be insignificant compared to L1-eGFP plasmid-driven expression.",[1],Medicine,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131023141020.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1080/08870446.2013.863883,Medicine_easy_586,Eating is no different.,The present study produced an alpha of .79. .,"Eating is no different. And since stress is often at the root of overeating, mindfulness seems to make us eat better meals, which means it's likely possible to lose weight without dieting. Apply that to a meal, and mindful eating means actually paying attention to the food you're eating, making you less likely to thoughtlessly plow through a bag of potato chips, for instance.","Before attempting to induce mindfulness without meditation, it is important to show that being higher in the trait of mindfulness and self-compassion results in better weight management. The present study produced an alpha of .79. . The overall scores range from 15 to 90 and the present study produced an alpha of .85.",[1],Medicine,train,1.0,news,http://time.com/4306564/mindfulness-diet-meditation/
10.1111/cobi.12126,Medicine_easy_587,Starbucks is at the forefront of a movement that will work to cull contributions to the 8 million metric tons of plastic already in the ocean.,"However, because our analyses included feeding studies, in which gut contents are investigated carefully, and studies reporting null ingestion, it is reasonable to expect that observed increases were not due to differences in necropsy methods among studies.","""It's about pointing out how prevalent single-use plastics are in our lives. Starbucks is at the forefront of a movement that will work to cull contributions to the 8 million metric tons of plastic already in the ocean. And while banning straws is only the beginning, it's at least a start.","As more studies were published on debris ingestion, researchers may have become more meticulous in their necropsy techniques. However, because our analyses included feeding studies, in which gut contents are investigated carefully, and studies reporting null ingestion, it is reasonable to expect that observed increases were not due to differences in necropsy methods among studies. Additionally, our finding of increasing plastic ingestion is consistent with findings of other researchers for both turtles and seabirds (e.g., .",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=34502185755&p=1pl&v=1&x=z0dO6Ks-U6rnp0rIiC7G-w
10.1016/j.jacc.2018.06.060,Medicine_easy_588,"In an accompanying editorial, Larry A. Weinrauch, MD, said that the study's small cohort may understate the importance of this problem for ART adolescents, especially since multiple birth pregnancies and maternal risk factors (such as eclampsia, chronic hypertension and diabetes) were excluded from the study.",Five control subjects and 3 ART subjects were taking noncardiac medication during the time of the study.,"These limitations may have resulted in a lower cardiovascular risk among the participants compared with the overall ART population. In an accompanying editorial, Larry A. Weinrauch, MD, said that the study's small cohort may understate the importance of this problem for ART adolescents, especially since multiple birth pregnancies and maternal risk factors (such as eclampsia, chronic hypertension and diabetes) were excluded from the study. ""Early study, detection and treatment of ART conceived individuals may be the appropriate course of preventative action,"" Weinrauch wrote.","None of the participants was born prematurely, mean gestational age was comparable in the 2 groups, and there were no pregnancy or perinatal complications. Five control subjects and 3 ART subjects were taking noncardiac medication during the time of the study. In 2 ART participants 24-h ambulatory BP could not be measured for technical reasons.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=35001649487&p=1pl&v=1&x=_q9H1m99amu0WPJ3O9Pclg
10.1001/jamaoncol.2016.6326,Medicine_easy_589,The extremely dense breast is completely white.,Estimates of the PARP are sensitive to changes in category definitions that alter the prevalence and relative risk of the risk factor.,"""It's a rather strong risk factor ... not as strong as age or known genetic mutations, but a strong risk factor,"" Lilge said. The extremely dense breast is completely white. Lumps, including cancers, are white,"" she said.",These factors represent clinically available information that can and should be used by clinicians to stratify breast cancer risk for improved risk-based screening and primary and secondary prevention efforts. Estimates of the PARP are sensitive to changes in category definitions that alter the prevalence and relative risk of the risk factor. Close attention to risk factor prevalence should be considered when applying our results to other populations.,[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=40341473566&p=1pl&v=1&x=te6VJw1kLgJ77y75GPojkg
10.1177/0190272516628298,Medicine_easy_590,Yet she also notes that credit cards offer the poor a source of funds that may help them through tough times that would otherwise be worse.,"As hypothesized, a much higher rate of exercise at campus facilities is reported on the survey (m = 1.74, s = 1.83) than can be validated in records (m = 1.08, s = 1.57), the difference reaching conventional levels of statistical significance (z = 7.8, p \ .001; see Figure 3 ).","Stavins found that 44% of adults have revolving credit, and these people typically have an outstanding balance of $6,600. It is worrisome that financially strapped Americans are incurring high interest payments on credit cards that reduce their already modest incomes, writes Stavins. Yet she also notes that credit cards offer the poor a source of funds that may help them through tough times that would otherwise be worse.","Comparison of the three data collection procedures demonstrates the effect of directiveness of measurement. As hypothesized, a much higher rate of exercise at campus facilities is reported on the survey (m = 1.74, s = 1.83) than can be validated in records (m = 1.08, s = 1.57), the difference reaching conventional levels of statistical significance (z = 7.8, p \ .001; see Figure 3 ). Similarly, survey data show a higher rate of reported exercise when compared with text message data.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=38281280455&p=1pl&v=1&x=DoxDPACO2UT3_YcaZG3y1g
10.3945/ajcn.110.010926,Medicine_easy_591,"""A good quality matcha is bright green and smooth.","For intervention groups, the mean change in blood HDL-cholesterol concentrations showed a favorable trend, but it was not significant.","Compared to the powders, matcha in tea bags provides significantly less EGCG. ""A good quality matcha is bright green and smooth. An average matcha will be yellow and grainy to touch--the tougher leaves of the tea bush,"" says Cheadle.","Therefore, safety issues need to be evaluated in the future under conditions of long-term and high-dose exposure. In conclusion, green tea significantly reduced serum total and LDL-cholesterol concentrations, and the changes were not influenced by the type of intervention, treatment doses of green tea catechins, study duration, individual health status, or quality of the study. For intervention groups, the mean change in blood HDL-cholesterol concentrations showed a favorable trend, but it was not significant.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33513986504&p=1pl&v=1&x=ngHC19jbm3s9fGg1jNED9A
10.3945/ajcn.2010.29269,Medicine_easy_592,Each one is not a Love Canal disaster waiting to happen.,"This review does not address potential health effects of differences in contaminant content (such as herbicide, pesticide, and fungicide residues) of organically and conventionally produced foodstuffs or of potential wider environmental or occupational health effects of different agricultural practices.","These dumps are not full of nuclear waste. Each one is not a Love Canal disaster waiting to happen. And as for the related notion that plastic is evil, it's yet another example of where environmentalists vastly overstate what scientists have actually found.","Conclusion: From a systematic review of the currently available published literature, evidence is lacking for nutrition-related health effects that result from the consumption of organically produced foodstuffs. This review does not address potential health effects of differences in contaminant content (such as herbicide, pesticide, and fungicide residues) of organically and conventionally produced foodstuffs or of potential wider environmental or occupational health effects of different agricultural practices. Establishing the strength of the existing evidence base that relates to nutrition-related health benefits of organic food consumption will assist policymakers in the development of evidence-based statements on potential public-health gains or risks that result from organic food consumption and support consumers to make informed choices.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=40057830393&p=1pl&v=1&x=c4t85s4dBchhLBbTWqEeyQ
10.1111/1471-0528.14528,Medicine_easy_594,"The review of 21 studies* included 20,160 women, and found that participants had 25 per cent better odds of improved health outcomes**, compared with non-participants.",Completed disclosure of interests form available to view online as supporting information.,"This is the case regardless of whether or not the treatment is found to be effective in the trial. The review of 21 studies* included 20,160 women, and found that participants had 25 per cent better odds of improved health outcomes**, compared with non-participants. The researchers hope the results may lead to more clinicians offering trials to their patients and more women volunteering for trials in a research area that currently faces many challenges.",None declared. Completed disclosure of interests form available to view online as supporting information. JZ and KK resolved the discrepancies between reviewers on data extraction.,[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/better-health-for-women-involved-in-clinical-trials/
10.1126/science.aac5082,Medicine_easy_595,"The discovery could lead to significant advances in health care, transportation, electronic communication and other areas.","The stress-strain curves of the HLEC and its silicone-containing layers (Ecoflex and Ecoflex-EL composite) are all coincident, whereas the elastic modulus of the hydrogel is two orders of magnitude lower, allowing the HLEC to stretch freely without delaminating.","Even in this age of smartphones and other electronics wonders, these ideas sound quite futuristic. The discovery could lead to significant advances in health care, transportation, electronic communication and other areas. ""This material can stretch with the body of a soft robot, and that's what our group does,"" Shepherd said, noting that the material has two key properties: ""It allows robots to change their color, and it also allows displays to change their shape.""","The HLEC (Fig. The stress-strain curves of the HLEC and its silicone-containing layers (Ecoflex and Ecoflex-EL composite) are all coincident, whereas the elastic modulus of the hydrogel is two orders of magnitude lower, allowing the HLEC to stretch freely without delaminating. 2A, data table S3 , and movie S1) show the excellent adhesion between the layers.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BO8EfoM22o0/
10.1111/bdi.12337,Medicine_easy_596,"In the study, the ratio of free to bound EPA correlated with clinical bipolar symptoms, specifically mania and tendency towards suicide.","Based on the clinical and neuroinflammatory links between BD and migraine, concurrent lowering of dietary n-6 in BD may also be necessary for effective treatment of bipolar disorder with n-3 PUFA supplementation (103).","""This means that the availability of omega-3 in the body is lower in bipolar subjects,"" Saunders said. In the study, the ratio of free to bound EPA correlated with clinical bipolar symptoms, specifically mania and tendency towards suicide. However, the researchers did not find altered ratios of omega-3 to omega-6 fatty acids in bipolar subjects.","Interestingly, both the L6 and the H3-L6 groups had increases in UE EPA, specifically, among PUFA (102). Based on the clinical and neuroinflammatory links between BD and migraine, concurrent lowering of dietary n-6 in BD may also be necessary for effective treatment of bipolar disorder with n-3 PUFA supplementation (103). Future studies of the specific signaling pathways and lipid mediators linking n-3 and n-6 PUFA to BD pathogenesis may lead to development of targeted dietary and medication strategies for treating BD.",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PW-ENSotbzs/
10.1105/tpc.17.00020,Medicine_easy_597,That's like turning off your radio and finding some songs still play as long as you turn up the volume.,"These examples demonstrate that some introns significantly boost expression, even in the absence of prior promoter activity.","The plants still turned blue as long as the gene contained an intron. That's like turning off your radio and finding some songs still play as long as you turn up the volume. A job for the junk

So what does this finding mean?","In other cases, the expression of genes that are weakly active without an intron can be increased 10-fold or more by the addition of an intron . These examples demonstrate that some introns significantly boost expression, even in the absence of prior promoter activity. First, the varying abilities of efficiently spliced introns to increase mRNA accumulation indicate that only certain introns boost mRNA levels beyond the general effects caused by the splicing machinery or exon junction complexes .",[1],Medicine,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/9UMX1H2x8hI/
10.1038/s41467-019-10460-1,Medicine_easy_598,This is the first therapeutic punch.,"4E , F), providing strong evidence for genomic instability and mitotic catastrophe.","This is the first therapeutic punch. Our approach could improve the effectiveness of chemotherapy in combination with PARP inhibitors and counteract the systematic resistance that develops with this treatment,"" said Mes-Masson, a researcher at the CRCHUM and professor at the Universite de Montreal. Future clinical trials in store?","4D ) and an increase in the micronuclei number (Supplementary Fig. 4E , F), providing strong evidence for genomic instability and mitotic catastrophe. Finally depleting either p21 or Chk2 redirected Olaparib-treated cells from senescence toward cell death, as observed by significantly decreased colony formation (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39437894437&p=1pl&v=1&x=ZBlmsrltN99UiFj8MtvN6w
10.1016/j.ijfoodmicro.2018.02.007,Medicine_easy_599,"advertisement

""In Finland, there is no urgent need to prevent Yersinia infections, but our study can serve as a model for the prevention of other, more serious foodborne infections through phage treatment,"" says Skurnik.",The genes predicted to encode structural proteins are located between genes g41 and g49.,"In this case as well, the phages effectively inhibited bacterial growth. advertisement

""In Finland, there is no urgent need to prevent Yersinia infections, but our study can serve as a model for the prevention of other, more serious foodborne infections through phage treatment,"" says Skurnik. In the future, decontamination with phages may well be part of the routine in processing food.","In the genome of fHe-Yen3-01, 56 genes were identified, and based on similarity searches, functions could be predicted only for 19 of them. The genes predicted to encode structural proteins are located between genes g41 and g49. 4A) , and the highest similarity was found between fHe-Yen3-01 and the virulent Yersinia phage ϕ80-18 [GenBank accession number: HE956710].",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33356795765&p=1pl&v=1&x=m6cNwovANRXnCyeSTCyreQ
10.1007/s00401-017-1680-3,Medicine_easy_600,"""It's all about informed choice.",The findings of multiple foci of tau-positive ATs and NFTs with more intense in the sulcal depths of the frontal and temporal cortices with a perivascular distribution were diagnostic of CTE .,"""It is disgraceful nothing concrete has been done since by the FA or the PFA. ""It's all about informed choice. On the back of a cigarette packet, smokers can read about risks to their health.","Examination of the brain showed moderate atrophy of the temporal lobes and hippocampi and fenestration of the septum pellucidum, with no evidence of metastatic tumour. The findings of multiple foci of tau-positive ATs and NFTs with more intense in the sulcal depths of the frontal and temporal cortices with a perivascular distribution were diagnostic of CTE . In addition, there was widespread tau pathology supportive of CTE with neuronal and glial inclusions in the superficial cortical layers.",[1],Medicine,train,1.0,news,http://healthmedicinet.com/news/football-headers-linked-to-brain-damage/
10.1126/science.aau9101,Medicine_easy_601,The fragments diffuse out of the solution and can be washed away.,The offset of the increased heating energy costs and a more detailed analysis of the overall energy savings can be found in fig.,"Lignin is a strong emitter of IR light, so Hu and his colleagues knew they had to ditch it. The fragments diffuse out of the solution and can be washed away. The new wood is more than just strong.","Therefore, cities in the Southwest may be the most suitable for the installation of this material to reduce energy consumption for cooling. The offset of the increased heating energy costs and a more detailed analysis of the overall energy savings can be found in fig. The results show that cities with hot and dry climates have the largest potential cooling energy savings.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=39296984172&p=1pl&v=1&x=qrXKCeLX4dRfawhqqfpjUw
10.1038/s41562-017-0189-z,Medicine_easy_602,"Lakens, 37, thought it was a disastrous idea.","However, the connection between the two quantities can be evaluated for particular test statistics under certain classes of plausible alternatives (Fig.","Lakens, 37, thought it was a disastrous idea. A lower a, or significance level, would require much bigger sample sizes, making many studies impossible. he says, ""Why prescribe a single p-value, when science is so diverse?""","By Bayes' rule, this ratio may be written as: There is no unique mapping between the P value and the Bayes factor, since the Bayes factor depends on H 1 . However, the connection between the two quantities can be evaluated for particular test statistics under certain classes of plausible alternatives (Fig. A two-sided P value of 0.05 corresponds to Bayes factors in favour of H 1 that range from about 2.5 to 3.4 under reasonable assumptions about H 1 (Fig.",[1],Medicine,train,1.0,news,http://ct.moreover.com/?a=33040029907&p=1pl&v=1&x=rQXyq8C5Bl3TR5A2u9xAfg
10.1037/0022-3514.87.5.665,Medicine_easy_606,"""At a smaller college there are less alternatives, and students are aware of that.""","However, the partner's arbitrary experimental code number (e.g., 12-31) happened to be the same as or different from participants' month and day of birth.","""On a larger campus people perceive that they have more flexibility in swapping out their friends,"" Bahns says. ""At a smaller college there are less alternatives, and students are aware of that."" Students may invest more in their friendships if they know they can't find someone new or if they think it would be hard to move in and out of relationships easily.","Because of changes in laboratory-space assignments, participants in Study 5a were able to see one another easily during the study, whereas participants in Study 5b were seated in a way that minimized visual contact. However, the partner's arbitrary experimental code number (e.g., 12-31) happened to be the same as or different from participants' month and day of birth. If implicit egotism influences interpersonal attraction, then participants who believe their partners' arbitrary code numbers resemble their own birthday numbers should rate their partners more favorably than usual.",[1],Medicine,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=a-friend-like-me
10.3389/neuro.01.1.1.006.2007,Medicine_easy_607,"If you're a parent, you'll treat your child in a different way.""",The presynaptic form of plasticity that is normally observed between these neurons was normal in the VPA treated slices.,"These children are hyperfunctional and they can't bear their environment,"" says Markan. ""If you have that view, it changes the way you look at research. If you're a parent, you'll treat your child in a different way.""",The results were also found for both layer 2/3 and in layer 5 pyramidal neurons and a closer examination revealed that the boosted plasticity was a postsynaptic form of plasticity. The presynaptic form of plasticity that is normally observed between these neurons was normal in the VPA treated slices. These results indicate that glutamatergic synapses are hyper-plastic in this animal model of autism.,[1],Medicine,train,1.0,news,http://time.com/3905841/autism-hyperfunctional/
10.1001/jamapsychiatry.2015.0575,Medicine_easy_608,"""So it's incredibly interesting that not only is hearing voices more common than previously thought, but it's not always linked to serious mental illness.""","The sequence of these follow-up probe types differed slightly between the first 6 WMH surveys, which were administered in Europe (Belgium, France, Germany, Italy, the Netherlands, and Spain), and those in the remaining 12 countries (eTables 1 and 2 in the Supplement).","These people seem to function reasonably well. ""So it's incredibly interesting that not only is hearing voices more common than previously thought, but it's not always linked to serious mental illness."" ""These people were representative of the general population, not seeking mental health assistance,"" says McGrath.","The weighted mean response rate is 72.1%. The sequence of these follow-up probe types differed slightly between the first 6 WMH surveys, which were administered in Europe (Belgium, France, Germany, Italy, the Netherlands, and Spain), and those in the remaining 12 countries (eTables 1 and 2 in the Supplement). Respondents may have had more than 1 hallucination and/or delusion type associated with a single episode of PE.",[1],Medicine,train,1.0,news,http://www.futurity.org/hallucinations-delusions-930802/
10.1093/jac/dku079,Medicine_easy_609,"""But we're keen not to point the finger at these plants.","All E. coli were positive for bla CTX-M and bla TEM , but negative for bla SHV (Table 1) .","""Stricter regulations and higher levels of treatment are needed if we are to halt the rise in antibiotic resistance in the environment,"" write the authors in their report. ""But we're keen not to point the finger at these plants. There's contribution from everywhere.""","Downstream of the WWTP, the human-associated ST3103 and ST38 were codominant in 2009, but neither of these STs was detected in 2011 samples, which were dominated by the well-recognized human diseaseassociated types ST131 (20%) and ST167 (25%) [ Table 2 and  Table S1 (available as Supplementary data at JAC Online)]. All E. coli were positive for bla CTX-M and bla TEM , but negative for bla SHV (Table 1) . Sequencing revealed all bla CTX-M -bearing isolates in 2011 carried bla CTX-M-15 and 54.5% of isolates in 2009 carried bla CTX-M-15 with the remainder carrying bla CTX-M-1 .",[1],Medicine,train,1.0,news,http://www.homelandsecuritynewswire.com/dr20140722-sewage-treatment-contributes-to-antibiotic-resistance
10.3945/jn.113.188441,Biology_1,"One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this.""","The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ).","Some South Koreans are a little steamed--and defensive--about the study's findings. One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this."" Love for the instant noodle spans generations--it reminds the elderly of post-Korean War recovery and for the young and busy, it's quick and cheap.","The exclusion of participants taking blood pressurelowering or lipid-lowering medications or who had a history of diabetes mellitus did not change the overall associations between dietary patterns and cardiometabolic risk factors. The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ). Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men.","[1.0, 2.0, 2.0]",Biology,train,1.6666666666666667,news,http://www.newser.com/story/192784/new-heart-disease-culprit-ramen.html
10.1073/pnas.1318978111,Biology_100,"When the team administered small doses of androgens to mice that were taking the equivalent of medications given to women undergoing IVF therapy, they developed more mature, egg-containing follicles than mice that didn't receive androgens.","Finally, we report that low doses of exogenous androgens enhance gonadotropin-induced ovulation in mice, further demonstrating the critical role that androgens play in follicular development and fertility.","""Androgens are increasing follicle growth and ensuring follicles don't die -- exactly what you want when providing fertility treatment,"" noted Hammes, who is also the chief of the Division of Endocrinology and Metabolism at UR Medicine's Strong Memorial Hospital. When the team administered small doses of androgens to mice that were taking the equivalent of medications given to women undergoing IVF therapy, they developed more mature, egg-containing follicles than mice that didn't receive androgens. The androgen-treated female mice also released larger numbers of eggs with ovulation.","Interestingly, we find that the scaffold molecule paxillin regulates both processes, making it a critical regulator of AR actions in the ovary. Finally, we report that low doses of exogenous androgens enhance gonadotropin-induced ovulation in mice, further demonstrating the critical role that androgens play in follicular development and fertility. These data may explain reported positive effects of androgens on ovulation rates in women with diminished ovarian reserve.","[4.0, 4.0, 5.0]",Biology,train,4.333333333333333,news,http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10336-017-1477-0,Biology_101,"And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage.",We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul.,"""We can't say definitively that the Liberian greenbul is the same bird as the icterine greenbul, but we have presented enough evidence that makes any other explanation seem highly unlikely."" And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage. But despite the thorough genetic analysis and unlikely alternative explanations, we can't yet say that the elusive birds absolutely, definitely don't exist - it looks like once something becomes a species, unspecying it is a tougher ask.","The presumed nuND2 appears to be highly conserved: the two icterinus sequences isolated were identical, 1 bp different from the leucolepis allele, with a further 2 bp distance to albigularis. We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul. Based on a short fragment of sequence, many of the nodes in the tree have equivocal bootstrap support, and it does not represent a robust greenbul phylogeny.","[4.0, 1.0, 4.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1007/s10336-017-1477-0,Biology_102,"In the end, the Liberian and icterine greenbuls turned out to share an astonishing amount of genetic similarities, much more than any other two species of greenbul.",We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul.,"According to the data, the most likely explanation for a lack of new Liberian greenbuls is the fact that they don't actually exist. In the end, the Liberian and icterine greenbuls turned out to share an astonishing amount of genetic similarities, much more than any other two species of greenbul. ""We can't say definitively that the Liberian greenbul is the same bird as the icterine greenbul, but we have presented enough evidence that makes any other explanation seem highly unlikely.""","The presumed nuND2 appears to be highly conserved: the two icterinus sequences isolated were identical, 1 bp different from the leucolepis allele, with a further 2 bp distance to albigularis. We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul. Based on a short fragment of sequence, many of the nodes in the tree have equivocal bootstrap support, and it does not represent a robust greenbul phylogeny.","[2.0, 2.0, 2.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1007/s10336-017-1477-0,Biology_103,"And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage.","S4 of the ESM), which was heterozygous C/T in the Liberian Greenbul but homozygous C/C in Icterine Greenbul 'ICT05'.","""We can't say definitively that the Liberian greenbul is the same bird as the icterine greenbul, but we have presented enough evidence that makes any other explanation seem highly unlikely."" And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage. But despite the thorough genetic analysis and unlikely alternative explanations, we can't yet say that the elusive birds absolutely, definitely don't exist - it looks like once something becomes a species, unspecying it is a tougher ask.","The Liberian Greenbul sequence was identical to that of the Icterine Greenbul from Liberia with the exception of one position (see Fig. S4 of the ESM), which was heterozygous C/T in the Liberian Greenbul but homozygous C/C in Icterine Greenbul 'ICT05'. This single SNP difference was verified in forward and reverse sequences.","[3.0, 2.0, 3.0]",Biology,train,2.6666666666666665,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1139/cjz-2017-0071,Biology_104,"""Very little is preventing their continued dispersal northward, provided they can survive winters.""","2010) , suggest that very little is preventing their continued dispersal northward, provided they can survive winters.","""Very little is preventing their continued dispersal northward, provided they can survive winters."" ""It was so exciting because it was further confirmation that this range expansion is still happening and that these animals are probably going to keep moving even further northward as the climate warms and as humans continue to alter the landscape with more agriculture and urbanization,"" Walsh says. ""Very little is preventing their continued dispersal northward, provided they can survive winters,"" Walsh says.","A lack of substantial landscape barriers for opossums , coupled with their nomadic behavior, illustrated by fathers and offspring discovered up to 33 km apart Beasley et al. 2010) , suggest that very little is preventing their continued dispersal northward, provided they can survive winters. Opossums collared with GPS units in Michigan had home ranges calculated between 10.9 and 200 hectares, depending on the equation used, with no difference between sexes .","[3.0, 5.0, 5.0, 5.0, 5.0]",Biology,train,4.6,news,http://www.futurity.org/virginia-opossum-range-1684512/
10.1186/s40168-015-0071-z,Biology_105,The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy.,"A broader range of bifidobacterial species were positively correlated with the amounts of overall bifidobacteria within secretor-fed infants than non-secretor-fed infants, suggesting that the presence of 2′-fucosylated sugars allows a broader array of bifidobacterial species to colonize the gut environment.","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","However, there was a large difference in which species of bifidobacteria thrived in each group of infants (defined as a species whose presence tended to lead to domination of the microbiota by bifidobacteria). A broader range of bifidobacterial species were positively correlated with the amounts of overall bifidobacteria within secretor-fed infants than non-secretor-fed infants, suggesting that the presence of 2′-fucosylated sugars allows a broader array of bifidobacterial species to colonize the gut environment. According to our fecal isolate data, bifidobacteria that can grow on 2′-fucosylated substrates are relatively uncommon, but represent a larger proportion of total bifidobacteria in secretor-fed infants, suggesting that this substrate is related to the competitive fitness of these strains.","[1.0, 3.0, 2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1002/emmm.201302567,Biology_108,"""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body.","SMN2 mis-splicing was exacerbated during late-stage disease, which should accelerate the decline.","""Our efforts to model the adult form of SMA were successful,"" says Kentaro Sahashi, M.D., Ph.D., a postdoctoral researcher and neurologist who is first author of the team's new paper. ""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body. We noted, importantly, marked liver and heart pathologies that were related to SMA's progression in adults.""","We found that ICV-administered ASO phenocopies adult-onset SMA. SMN2 mis-splicing was exacerbated during late-stage disease, which should accelerate the decline. In addition, systemically administered exon-skipping ASO also affected survival, resulting in striking liver and heart lesions, and the combination of central and peripheral administration exacerbated the pathology.","[3.0, 4.0, 5.0, 4.0, 4.0]",Biology,train,4.0,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-019-09863-x,Biology_11,The interdisciplinary research team hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios and help guide policy-makers towards prudent decisions on emissions reduction targets.,"Considering the nonlinear Arctic feedbacks makes the 1.5°C target marginally more economically attractive than the 2°C target, although both are statistically equivalent.","In both cases, the primary driver behind the additional costs is the emitted permafrost carbon. The interdisciplinary research team hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios and help guide policy-makers towards prudent decisions on emissions reduction targets. ""These two components are set to peak for global temperatures within the range covered by the Paris Agreement, but if the climate warms further, the summer and spring sea ice and land snow covers will retreat further north and the albedo feedback will actually weaken.","Combined, these two factors lead to significant increases in the mean discounted economic effect of climate change: +4.0% ($24.8 trillion) under the 1.5°C scenario, +5.5% ($33.8 trillion) under the 2°C scenario, and +4.8% ($66.9 trillion) under mitigation levels consistent with the current national pledges. Considering the nonlinear Arctic feedbacks makes the 1.5°C target marginally more economically attractive than the 2°C target, although both are statistically equivalent. T he Arctic region is warming twice as fast as the global average 1 , manifested by a decrease in sea ice, snow and glaciers and permafrost degradation relative to their benchmark average states for the period between 1979 and 2005 .","[1.0, 1.0, 2.0, 2.0, 1.0]",Biology,train,1.4,news,https://www.sciencedaily.com/releases/2019/04/190423114027.htm
10.1111/gcb.13276,Biology_111,"""In our study, we observed a widely variable bleaching and mortality response among corals,"" Marcelino says.","Coral colonies, inhabiting the same reef and apparently exposed to identical conditions, will bleach and die at different rates Obura, 2001; .","Rainforests of the sea

The index provides a valuable new tool to conservationists and park managers committed to preserving coral reefs and scientists interested in learning more about the hundreds of reef-building corals. ""In our study, we observed a widely variable bleaching and mortality response among corals,"" Marcelino says. ""Now, with the index, we have a platform we can use to better understand bleaching mechanisms, both intrinsic and environmental.","Within a bleaching event, coral susceptibility to stress is highly uneven. Coral colonies, inhabiting the same reef and apparently exposed to identical conditions, will bleach and die at different rates Obura, 2001; . Knowing which of many potential factors determine differential bleaching susceptibility among taxa will be essential to understanding bleaching mechanisms, and to preserve, manage, or reconstruct coral assemblages.","[4.0, 4.0, 5.0, 5.0]",Biology,train,4.5,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1038/s41467-018-08278-4,Biology_112,"That cartilage is a key part of joints, and shows definite progress in limb regeneration.",The regenerated cartilage grew well beyond the amputation plane (Fig.,"Without the proteins, the amputated toes would've healed over as normal. That cartilage is a key part of joints, and shows definite progress in limb regeneration. ""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper.",BMP9 induced a robust chondrogenic response in all of the digits analyzed at 7 days (n = 4). The regenerated cartilage grew well beyond the amputation plane (Fig. 3b) and cells are immunopositive for Sox9 and Acan (Fig.,"[5.0, 3.0, 4.0, 2.0, 3.0]",Biology,train,3.4,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1186/s40168-015-0071-z,Biology_113,"advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces.",Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).,"The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother. advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces. ""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said.","Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ). Of 35 milks from non-secretors, 20 of the matched infant stool samples were Low-Bif qPCR (57.1%).","[3.0, 4.0, 5.0, 4.0, 5.0]",Biology,train,4.2,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2013.08.004,Biology_115,These drugs also might have broader therapeutic value for patients with mental health issues.,"Thus SIK1 provides negative feedback, acting to suppress the effects of light on the clock.","The findings reveal a little bit more about how our internal clocks function. In addition, the research could pave the way for drugs that could bring bodies in tune with the solar cycle more quickly. These drugs also might have broader therapeutic value for patients with mental health issues.","Knockdown of Sik1 within the SCN results in increased behavioral phase shifts and rapid re-entrainment following experimental jet lag. Thus SIK1 provides negative feedback, acting to suppress the effects of light on the clock. This pathway provides a potential target for the regulation of circadian rhythms.","[1.0, 1.0, 3.0, 2.0, 1.0]",Biology,train,1.6,news,http://www.scienceworldreport.com/articles/9204/20130902/what-causes-jet-lag-internal-clock-slow-change-time.htm
10.1073/pnas.1504869112,Biology_116,The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death.,"Lianas, per-unit biomass, have a much stronger competitive effect on trees than do other trees (3), and our findings appear to represent the unique effect of lianas on forest carbon dynamics and not merely the effect of biomass removal.","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Because biomass dynamics of lianas are included in the whole-forest estimates, our findings corroborate earlier research that lianas themselves do not compensate for the loss in tree biomass that they cause . Lianas, per-unit biomass, have a much stronger competitive effect on trees than do other trees (3), and our findings appear to represent the unique effect of lianas on forest carbon dynamics and not merely the effect of biomass removal. This point is confirmed by our inclusion of lianas in the biomass calculations in the control plots.","[4.0, 3.0, 5.0]",Biology,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1098/rsos.180695,Biology_117,"The survey of U.S. indoor climate preferences in 37 states shows that, on average, Americans keep their home climate similar to the outdoor climate of northeast Africa, with outdoor conditions in west central Kenya the most similar to conditions in American homes.","Overall, we identified the geographical distribution of the global outdoor climate that is most similar to the interiors of our study homes and summarized study home indoor climate preferences.","The survey of U.S. indoor climate preferences in 37 states shows that, on average, Americans keep their home climate similar to the outdoor climate of northeast Africa, with outdoor conditions in west central Kenya the most similar to conditions in American homes. There was some variation in American responses. For example, citizens in North Carolina reported indoor conditions most like those in Namibia, which is in southern Africa and south of the equator.","We found that the indoor climates of our study homes largely matched the TNZ of humans and other primates. Overall, we identified the geographical distribution of the global outdoor climate that is most similar to the interiors of our study homes and summarized study home indoor climate preferences. It would be difficult to convincingly argue that the behaviours leading to the construction of human houses are under direct selection.","[4.0, 3.0, 2.0, 5.0, 4.0]",Biology,train,3.6,news,http://ct.moreover.com/?a=38804472041&p=1pl&v=1&x=HgOgei0b1kV3BVEuJ5LhBA
10.1038/s41467-018-07557-4,Biology_118,"""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper.","Moreover, we were able to quantify and show the magnitude of infrastructure at risk across the circumpolar permafrost domain.","The team found that 3.6 million people--three quarters of the current population in the Northern Hemisphere permafrost area--may be affected by infrastructure damage from permafrost thaw. ""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper. The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports.","Consequently, detailed hazard maps and geospatial data-based computations, such as those presented here, are of importance to enable planners and policymakers to identify both high-and low hazard areas when planning future infrastructure at urban and settlement scales 33 . Moreover, we were able to quantify and show the magnitude of infrastructure at risk across the circumpolar permafrost domain. The major advantage of the approach presented here is that hazard quantification can be conducted with any available infrastructure or population dataset (also using planned infrastructure and future population if suitable high-quality datasets and projections are available) and for any policy-relevant global warming scenario.","[3.0, 5.0, 4.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=37954092559&p=1pl&v=1&x=m3BMJF9FCb6eVFPBkTQfrg
10.1098/rsos.171474,Biology_119,"The task force also ""concluded that violent video game use is a risk factor for adverse outcomes, but found insufficient studies to examine any potential link between violent video game use and delinquency or criminal behavior.""",Measurement flexibility also extends to a number of outcome assessments employed in the gaming literature.,"That task force ""found that violent video game exposure was associated with: an increased composite aggression score; increased aggressive behavior; increased aggressive cognitions; increased aggressive affect, increased desensitization, and decreased empathy; and increased physiological arousal."" The task force also ""concluded that violent video game use is a risk factor for adverse outcomes, but found insufficient studies to examine any potential link between violent video game use and delinquency or criminal behavior."" In Przybylski and Weinstein's review of prior literature, the two researchers strongly argue that earlier research is beset with such problems.",Such a pattern could lead researchers to make the spurious claim that playing the 2004 Xbox game Spider Man 2 is a significant catalyst for adolescent promiscuity . Measurement flexibility also extends to a number of outcome assessments employed in the gaming literature. A similar tractability is present in behavioural measurements of aggression.,"[2.0, 1.0, 3.0, 1.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1186/s40168-015-0071-z,Biology_12,The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy.,"Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05).","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ). Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05). The aggregated secretor-fed infant samples were, on average, found to have significantly higher absolute levels of bifidobacteria (10 9 .0 /g feces versus 10","[4.0, 3.0, 3.0, 3.0, 1.0]",Biology,train,2.8,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1016/j.neuron.2014.05.028,Biology_120,"Potential drug target for PTSD prevention

The dark smudge on the left side shows that the gene Tac2 is robustly activated after fear learning in the central amygdala.","Together, these studies further our understanding of the role of the Tac2 gene and CeM in fear processing and may provide approaches to intervention for fear-related disorders.","Potential drug target for PTSD prevention

The dark smudge on the left side shows that the gene Tac2 is robustly activated after fear learning in the central amygdala. The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder). ""PTSD is unique among psychiatric disorders in that we know when it starts - at the time of the trauma.","Concordantly, silencing of Tac2-expressing neurons in CeA with DREADDs impairs fear consolidation. Together, these studies further our understanding of the role of the Tac2 gene and CeM in fear processing and may provide approaches to intervention for fear-related disorders. Specifically relevant is the memory consolidation phase following emotional learning, since it is required to stabilize the initial fear memory trace.","[3.0, 4.0, 1.0, 4.0, 4.0]",Biology,train,3.2,news,http://www.healthcanal.com/mental-health-behavior/52580-potential-drug-target-for-ptsd-prevention.html
10.1002/emmm.201302567,Biology_121,The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.,"A single injection had dose-dependent effects on SMN2 splicing in the CNS, correlating with lifespan, growth and motor-function phenotypes (Figs 1 and 3) .","Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA. How much a patient is helped depends on the number of copies of the SMN2 gene they possess.","By inhibiting SMN2 exon 7 inclusion with an appropriate ASO in neonatal or adult (this study) transgenic mice, we elicited phenotypes resembling canonical SMA. A single injection had dose-dependent effects on SMN2 splicing in the CNS, correlating with lifespan, growth and motor-function phenotypes (Figs 1 and 3) . Notably, compared with our previous finding that neonatal ICV injection causes progressive paralysis, beginning after 2 weeks , in the present study, abnormal gait or rearing became apparent only 1 month after ASO injection.","[2.0, 2.0, 1.0, 3.0]",Biology,train,2.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1038/s41467-017-01957-8,Biology_122,"However, as soon as the ciliates were also allowed to evolve, protection came at a high cost to the bacteria: they then only produced few offspring.","Furthermore, coevolved ciliates had a significantly higher growth rate compared to the ancestral ciliates at a given coevolved bacteria population ( Fig.","Costly defence

As long as the scientists allowed only the bacteria to evolve in their experiments and computer simulations, the bacteria were able to protect themselves well from being eaten - with acceptable effort. However, as soon as the ciliates were also allowed to evolve, protection came at a high cost to the bacteria: they then only produced few offspring. In contrast, if the predator cannot adapt, the prey requires fewer resources for defence and can invest more in producing progeny"", explains Becks.","1a , Kruskal-Wallis ancestral vs. coevolved bacteria: χ 2 = 6.2, df = 1, p = 0.005). Furthermore, coevolved ciliates had a significantly higher growth rate compared to the ancestral ciliates at a given coevolved bacteria population ( Fig. 1b-d , coevolved bacteria population 1: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 5.4, df = 1, p = 0.007; bacteria population 2: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 5.4, df = 1, p = 0.007; bacteria population 3: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 4.3, df = 1, p = 0.025).","[4.0, 5.0, 3.0, 3.0]",Biology,train,3.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.3945/jn.113.188441,Biology_123,"Eating instant noodles at least twice a week was associated with 68% more cardiometabolic syndrome for women, regardless of what else their diet was made up of.","Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) .","Neither of those diets on the whole were associated with an uptick in cardio-metabolic syndrome--which is a collection of risk factors for heart disease, type-2 diabetes and stroke including high blood pressure, blood sugar, and cholesterol. Eating instant noodles at least twice a week was associated with 68% more cardiometabolic syndrome for women, regardless of what else their diet was made up of. This effect was only seen in women.","In addition, the mean sodium intake was very high across all categories (age-standardized mean sodium intake: 6.0 g in men, 4.2 g in women). Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) . Interestingly, although participants in the highest quintile of the MP had a higher education/income level than participants in the lowest quintile, frequent consumers of instant noodles had lower educational/income levels than did infrequent instant noodle consumers.","[2.0, 1.0, 4.0, 2.0, 4.0]",Biology,train,2.0,news,http://time.com/3149497/instant-noodles-heart-risks/
10.1038/s41589-018-0155-8,Biology_124,"advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says.","We found that infection with a persistent dose of Cl13 caused a striking pathological response in ABHD -/mice, indicated by hunched posture, ruffled fur, labored breathing, and death in ~ 50% of the animals (Fig.","Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so. advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says. The findings suggest several possibilities to investigate with future research.","Relief of immune suppression by blocking negative regulatory molecules like PD-1 or IL-10 results in hastened control of Cl13 infection, as well as concomitant immune pathology that can produce severe morbidity and lethality . We found that infection with a persistent dose of Cl13 caused a striking pathological response in ABHD -/mice, indicated by hunched posture, ruffled fur, labored breathing, and death in ~ 50% of the animals (Fig. 6a) , correlating with gross lung damage ( Supplementary Fig.","[3.0, 4.0, 5.0, 3.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/s41467-018-04355-w,Biology_125,"Also, when looking at tumor samples from patients, they found that tumors with high amounts of the fibrin cross-linking was associated with an increased risk of the tumor spreading.",This novel mechanism is reflected in clinical samples where fibrin cross-linking is correlated with poor survival.,"They also demonstrated that the presence of a clot made it easier for cancer cells to move and migrate. Also, when looking at tumor samples from patients, they found that tumors with high amounts of the fibrin cross-linking was associated with an increased risk of the tumor spreading. The researchers were able to reduce metastases by using a compound that blocks CCR2, a receptor on the surface of the inflammatory monocytes.","Our results have identified a previously unappreciated driver of LUSC metastasis characterized by CCL2-mediated recruitment of IMs and FXIIIA-mediated fibrin cross-linking in the TME, which provides a scaffold for tumor cell invasion. This novel mechanism is reflected in clinical samples where fibrin cross-linking is correlated with poor survival. Thus, IMs in LUSC tumors represent an important contextspecific vulnerability of this difficult-to-treat disease.","[2.0, 4.0, 1.0, 2.0, 2.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=34143256224&p=1pl&v=1&x=_B116Taw-aRVfBzYTF8X0Q
10.1002/emmm.201302567,Biology_127,"(click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults.","Patients with severe SMA show symptoms shortly after birth, suggesting a potential developmental component of SMA pathogenesis.","Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views). (click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults. Hence the importance of the team's success, reported online today in EMBO Molecular Medicine.","Compared with early-onset SMA, adult-onset SMA may have distinct pathology, as well as therapeutic responses and requirements, perhaps reflecting key differences between development and post-development. Patients with severe SMA show symptoms shortly after birth, suggesting a potential developmental component of SMA pathogenesis. ASO injection into the CNS of adult SMN2-transgenic mice mimicked adult-onset SMA, with a characteristic late-onset motor phenotype.","[3.0, 1.0, 4.0, 3.0, 2.0]",Biology,train,2.6,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1016/j.molcel.2014.05.030,Biology_129,Having a problem with the MC1R pathway raises a person's lifetime risk of melanoma about four-fold.,"Though MC1R dysfunction is clearly linked with defective tanning , MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation .","D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study. The team hopes to use this information to develop new melanoma-preventive treatments, like additives that can be included in sunblocks to ramp up the skin's ability to deal with UV damage. Having a problem with the MC1R pathway raises a person's lifetime risk of melanoma about four-fold.","R151C, R160W and D294H) exhibit a fair-skinned sun-sensitive phenotype and have up to a four-fold increased lifetime risk of melanoma . Though MC1R dysfunction is clearly linked with defective tanning , MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation . ATR (ATM and Rad3-related) is critical to UV DNA damage signaling and is intimately linked with NER (Bomgarden et al., 2006; .","[3.0, 4.0, 3.0, 3.0, 1.0]",Biology,train,2.8,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1002/emmm.201302567,Biology_13,The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.,"SMN2 mis-splicing was exacerbated during late-stage disease, which should accelerate the decline.","Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA. How much a patient is helped depends on the number of copies of the SMN2 gene they possess.","We found that ICV-administered ASO phenocopies adult-onset SMA. SMN2 mis-splicing was exacerbated during late-stage disease, which should accelerate the decline. In addition, systemically administered exon-skipping ASO also affected survival, resulting in striking liver and heart lesions, and the combination of central and peripheral administration exacerbated the pathology.","[2.0, 2.0, 4.0]",Biology,train,2.6666666666666665,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1098/rsos.171474,Biology_130,"""Despite interest in the topic by parents and policy-makers, the research has not demonstrated that there is cause for concern.""","1. female observed variables (jrjs ¼ 0.08-0.62), and subjective game engagement was positively correlated with overall levels of game engagement, any violent game engagement and overall levels of violent game engagement (rs ¼ 0.18-0.43).","""Despite interest in the topic by parents and policy-makers, the research has not demonstrated that there is cause for concern."" ""Despite interest in the topic by parents and policy-makers, the research has not demonstrated that there is cause for concern."" Oxford says that the study is one of the most definitive to date, using a combination of subjective and objective data to measure teen aggression and violence in games (see also: ""No link found between violent video games and behavior,"" HSNW, 4 January 2019).","8. 1. female observed variables (jrjs ¼ 0.08-0.62), and subjective game engagement was positively correlated with overall levels of game engagement, any violent game engagement and overall levels of violent game engagement (rs ¼ 0.18-0.43). Importantly, trait-level aggression as reported by adolescents was strongly correlated with higher carer reports of aggressive behaviour as measured in the SDQ, r ¼ 0.62, p , 0.001, supporting the notion that our criterion measure was a valid indicator of aggressive behaviour.","[1.0, 2.0, 3.0, 1.0, 2.0]",Biology,train,1.8,news,http://ct.moreover.com/?a=38630667262&p=1pl&v=1&x=eg7bkQTzSVqLm5ru549FjQ
10.1038/s41467-019-08382-z,Biology_131,These interactions help Hel2 identify flaws in protein formation.,Western blot analyses showed that the truncated proteins were more abundant than wild-type Hel2 (~1.8-fold for Hel2 1-543 and~1.9fold for Hel2 ).,"This clears the way for further proteins to be produced. These interactions help Hel2 identify flaws in protein formation. When researchers removed the parts of Hel2 in direct contact, this prevented the destruction of faulty proteins, showing that these contacts are important for the mechanism.",6a ). Western blot analyses showed that the truncated proteins were more abundant than wild-type Hel2 (~1.8-fold for Hel2 1-543 and~1.9fold for Hel2 ). Both truncated proteins also purified more efficiently in the CRAC procedure (~1.5-2.1-fold more efficiently for Hel2 1-543 and~2.4-8.4-fold more efficiently for Hel2 1-492 ) as determined following tobacco etch virus (TEV) elution (Supplementary Fig.,"[3.0, 3.0, 2.0, 4.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=38442592628&p=1pl&v=1&x=6qnjJlZN_F0RgmqDHnl0dA
10.1016/j.cmet.2015.02.003,Biology_132,"""A further understanding of the regulatory cascades might not only help to design drugs that specifically enhance local salt deposition and help to combat infectious diseases,"" Jantsch said, ""but also may lead to novel strategies to mobilize sodium stores in the aging population and prevent cardiovascular disease.","Finally, we found that increasing Na + content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense.","The findings, though, may lead to a supplement version of sodium in order to protect the heart and other organs from the negative impacts high-salt diets have on the body, while still achieving a positive immunal response. ""A further understanding of the regulatory cascades might not only help to design drugs that specifically enhance local salt deposition and help to combat infectious diseases,"" Jantsch said, ""but also may lead to novel strategies to mobilize sodium stores in the aging population and prevent cardiovascular disease. We also think that local application of high-salt-containing wound dressings and the development of other salt-boosting antimicrobial therapies might bear therapeutic potential.""","This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control. Finally, we found that increasing Na + content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense. We suggest that the hypertonic microenvironment could serve as a barrier to infection.","[1.0, 4.0, 3.0, 4.0, 3.0]",Biology,train,3.0,news,http://www.medicaldaily.com/blood-pressure-and-heart-condition-risks-aside-high-salt-diets-may-improve-immune-324200
10.3945/jn.113.188441,Biology_133,This association was found to be particularly strong for women.,"Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) .","4: Fried food

5: Fast food including instant noodles

Consumption of instant noodles is associated with an increased prevalence of metabolic syndrome

It was observed that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome in women which was independent of major dietary patterns. This association was found to be particularly strong for women. These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs.","In addition, the mean sodium intake was very high across all categories (age-standardized mean sodium intake: 6.0 g in men, 4.2 g in women). Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) . Interestingly, although participants in the highest quintile of the MP had a higher education/income level than participants in the lowest quintile, frequent consumers of instant noodles had lower educational/income levels than did infrequent instant noodle consumers.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.1111/1365-2656.12871,Biology_136,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.","The threat of diseases to wildlife populations, and the efficiency of pathogens as biocontrol agents, can only be evaluated with an adequate understanding of how different components F I G U R E 2 Estimated average changes in monthly survival rates of rabbits in different disease states, namely (i) susceptible to rabbit haemorrhagic disease virus (RHDV) and immune to myxoma virus (MYXV) (red bars), (ii) susceptible to MYXV and immune to RHDV (blue bars), (iii) susceptible to both RHDV and MYXV (green bars) and (iv) young rabbits <90 days old of various disease states, including individuals with maternal antibodies against RHDV and/ or MYXV (purple bars).","""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","Capture rates in most capture sessions were <40% and varied over time (Supporting Information Figure S9 ), likely explaining why uncertainty in the estimates of individual disease states and the time-specific disease effect on rabbit survival led to large credible intervals. The threat of diseases to wildlife populations, and the efficiency of pathogens as biocontrol agents, can only be evaluated with an adequate understanding of how different components F I G U R E 2 Estimated average changes in monthly survival rates of rabbits in different disease states, namely (i) susceptible to rabbit haemorrhagic disease virus (RHDV) and immune to myxoma virus (MYXV) (red bars), (ii) susceptible to MYXV and immune to RHDV (blue bars), (iii) susceptible to both RHDV and MYXV (green bars) and (iv) young rabbits <90 days old of various disease states, including individuals with maternal antibodies against RHDV and/ or MYXV (purple bars). We show that despite a strongly seasonal force of infection (FoI) for RHDV and MYXV, it is likely that susceptible rabbits can be infected (at least at low levels) throughout the year, having implications for rabbit conservation and biocontrol.","[3.0, 3.0, 3.0, 3.0, 1.0]",Biology,train,2.6,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1210/en.2015-2036,Biology_138,"They found that in cases in which vitamin D was lacking from the diet or in which cells were missing much of the VDR protein, tumor cells expressed more of a gene called ID1, which has been shown to play a role in breast cancer metastasis.","We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression.","In contrast, none of the tumors in the 10 mice that received unmodified 168FARN cells spread to the liver during the study period. They found that in cases in which vitamin D was lacking from the diet or in which cells were missing much of the VDR protein, tumor cells expressed more of a gene called ID1, which has been shown to play a role in breast cancer metastasis. Further investigation showed that VDR binds directly to a stretch of DNA near the ID1 gene and suppresses its expression in both mouse and human cells.","Further, we discovered that attenuated vitamin D signaling due to Vdr ablation enhances tumor progression and, importantly, is sufficient to enable metastases, which are the primary cause of treatment failure and death for patients with BCa. We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression. Interestingly, Sherman et al found a tumor cell nonautonomous mechanism for VDR signaling to inhibit pancreatic ductal adenocarcinoma progression and Fernandez-Garcia et al found that calcitriol induces, rather than inhibits, Id1 expression in a colon carcinoma cell line.","[3.0, 4.0, 3.0, 1.0, 4.0]",Biology,train,3.0,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1038/ncomms4632,Biology_139,The researchers address two major issues for nanomotors so far: assembly and controls.,"The nanomotors, with all the dimensions o1 mm, can robustly rotate for 15 h for 4240,000 cycles and were demonstrated for controllable biochemical release.","""We believe it will help advance the study of drug delivery and cell-to-cell communications."" The researchers address two major issues for nanomotors so far: assembly and controls. The researchers found that they could position the nanomotors in a pattern and move them in a synchronized fashion, which makes them more powerful and gives them more flexibility.","Also, limited by the characteristics of natural molecular motors, the devices could not alter either their rotation or speed. The nanomotors, with all the dimensions o1 mm, can robustly rotate for 15 h for 4240,000 cycles and were demonstrated for controllable biochemical release. The innovation in this research may inspire multiple research fields including MEMS/NEMS, bio-NEMS, micro/nanofluidics and lab-on-a-chip architecture.","[1.0, 4.0, 2.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s40168-015-0071-z,Biology_14,The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy.,"Results: On average, bifidobacteria were established earlier and more often in infants fed by secretor mothers than in infants fed by non-secretor mothers.","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","Results: On average, bifidobacteria were established earlier and more often in infants fed by secretor mothers than in infants fed by non-secretor mothers. In secretor-fed infants, the relative abundance of the Bifidobacterium longum group was most strongly correlated with high percentages of the order Bifidobacteriales. Conversely, in non-secretor-fed infants, Bifidobacterium breve was positively correlated with Bifidobacteriales, while the B. longum group was negatively correlated.","[3.0, 2.0, 1.0, 3.0]",Biology,train,2.25,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1016/j.cell.2018.04.034,Biology_140,"The CDK12 mutant tumors also displayed characteristic copy number and mutational signatures, which characterized the tumors as distinct from the HRD or MMRD type of prostate cancer.",CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion.,"The CDK12 mutants in addition exhibited a distinct transcriptional phenotype and a shift from oxidative to glycolytic metabolism, which is a hallmark of many types of cancer, but is generally not characteristic of most prostate cancers, they add. The CDK12 mutant tumors also displayed characteristic copy number and mutational signatures, which characterized the tumors as distinct from the HRD or MMRD type of prostate cancer. ""In particular, CDK12-mutants are different from tumors with HRD, which was previously presumed to be the pathway through which CDK12 regulated genomic instability,"" they point out.",CDK12 mutant cases are baseline diploid and do not exhibit DNA mutational signatures linked to defects in homologous recombination. CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion. FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication.,"[3.0, 2.0, 2.0, 3.0, 2.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1038/ncomms4632,Biology_141,"The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications.",The demonstration of nanomotors for biochemical release as shown above is still in a non-bioenvironment.,"The team's nanomotor is an important step toward developing miniature machines that could one day move through the body to administer insulin for diabetics when needed, or target and treat cancer cells without harming good cells. The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications. Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power.","Such molecule release mechanism is applicable not only to Raman-sensitive molecules but also to any biochemicals of interests, such as drugs, cytokine, DNA, antigens and antibodies. The demonstration of nanomotors for biochemical release as shown above is still in a non-bioenvironment. More experiments are necessary to study the applications and limitations of nanomotors in a biosetting.","[1.0, 3.0, 3.0]",Biology,train,2.333333333333333,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/sciadv.aau1291,Biology_142,"This way of delivering drugs also has the advantage of not increasing the local pressure where the drug exits the device because the drug molecules are not in a solvent - they exit the device ""dry"".","This ""dry"" delivery enables precise drug release into the brain region with negligible local pressure increase.","We show that the implant can treat problems in the brain, such as epileptic seizures, by delivering brain chemicals - known as neurotransmitters - directly to the cells in the brain that cause the problem. This way of delivering drugs also has the advantage of not increasing the local pressure where the drug exits the device because the drug molecules are not in a solvent - they exit the device ""dry"". This stopped the seizures.","We demonstrate the utility of direct in situ electrophoretic drug delivery to treat neurological disorders. This ""dry"" delivery enables precise drug release into the brain region with negligible local pressure increase. The therapeutic potential of the FIP probe is tested in a rodent model of epilepsy.","[4.0, 2.0, 3.0, 4.0]",Biology,train,3.25,news,http://ct.moreover.com/?a=34961518391&p=1pl&v=1&x=gYock5HcirAl4GI18svsfA
10.1016/j.celrep.2016.08.013,Biology_143,"Additional calculations revealed that the propulsive force generated by bacterial motility is stronger than the forces imposed on bacteria by flow, suggesting that the microbes may use rotating internal structures called flagella to actively migrate along blood vessel walls and exit the vasculature to reach specific tissues, even under the force conditions generated by blood flow.","Furthermore, we found that the forces imposed on adhesive bonds under flow may be small enough to permit active migration driven by bacterial flagellar motors.","This repeating cycle allowed the bacteria to stably move over the endothelial surface at a constant overall speed, similar to the way immune cells called leukocytes move through blood vessels. Additional calculations revealed that the propulsive force generated by bacterial motility is stronger than the forces imposed on bacteria by flow, suggesting that the microbes may use rotating internal structures called flagella to actively migrate along blood vessel walls and exit the vasculature to reach specific tissues, even under the force conditions generated by blood flow. ""The ability of Lyme disease bacteria to disseminate using the network of rivers and streams provided by the bloodstream, and the ability to catch onto the banks of these rivers and streams, would likely be very important for spreading throughout the body, because they can overcome the barrier to dissemination caused by blood flow,"" says first author Rhodaba Ebady of the University of Toronto.","Here, we show that endothelial interactions of the Lyme disease spirochete Borrelia burgdorferi under physiological shear stress mechanistically resemble selectin-dependent leukocyte rolling. Furthermore, we found that the forces imposed on adhesive bonds under flow may be small enough to permit active migration driven by bacterial flagellar motors. These findings provide insight into the biomechanics of bacterial-vascular interactions and demonstrate that disseminating bacteria and circulating host immune cells share widely conserved mechanisms for interacting with endothelia under physiological shear stress.","[4.0, 3.0, 4.0, 3.0, 3.0]",Biology,train,3.4,news,https://www.sciencedaily.com/releases/2016/08/160825130027.htm
10.1073/pnas.1504869112,Biology_144,"""It suggests that over the decades to come, lianas could increasingly suppress the ability of tropical forests to sequester carbon.""",These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .,"The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining. ""This is the first time the effect of lianas on carbon cycling has been shown in such detail and on a large scale,"" Powers says. ""It suggests that over the decades to come, lianas could increasingly suppress the ability of tropical forests to sequester carbon.""","The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( . Nonetheless, these initial studies indicate that increasing liana abundance may alter the carbon balance and cycle of tropical forests by reducing forestlevel carbon storage and sequestration.","[5.0, 4.0, 4.0, 5.0, 4.0]",Biology,train,4.4,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1016/j.cell.2015.07.058,Biology_145,"""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea.",MRN senses and binds to early replicating virus genomes where it recruits ATM and activates a localized signaling response that selectively prevents virus genome replication.,"This means the virus is effectively ignored while the cell responds to the more massive alarm. ""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","The localized MRN-ATM response provides an elegant mechanism to selectively neutralize viral replication without jeopardizing cellular replication and viability. MRN senses and binds to early replicating virus genomes where it recruits ATM and activates a localized signaling response that selectively prevents virus genome replication. In WT Ad5-infected cells, E1B-55K and E4-ORF3 inactivate MRN and enable virus genome replication.","[2.0, 3.0, 2.0]",Biology,train,2.333333333333333,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1016/j.cub.2018.06.016,Biology_146,"The presence of another fish that is not socially engaged is insufficient to trigger interaction regardless of their proximity, a finding that mirrors reciprocal social interaction in humans.",Our data show that social engagement in zebrafish requires a behavioral visual stimulus provided by another socially engaged fish.,"Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting. The presence of another fish that is not socially engaged is insufficient to trigger interaction regardless of their proximity, a finding that mirrors reciprocal social interaction in humans. The research team noted that the findings ""are promising for future studies into the visual circuitry required to drive social behavior.""","Based on their anatomical location and gene expression patterns, these cells may be homologous to a population of lhx8-expressing, cholinergic basal forebrain neurons that is also found in mammals . Our data show that social engagement in zebrafish requires a behavioral visual stimulus provided by another socially engaged fish. We demonstrated that both pharmacological manipulation of dopaminergic systems and ablation of a portion of the ventral telencephalon produce predictable deficits in social behavior.","[1.0, 3.0]",Biology,train,5.0,news,http://ct.moreover.com/?a=34657319504&p=1pl&v=1&x=IZljwk13voqosD3secxjLg
10.3945/jn.113.188441,Biology_147,"""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said.","Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men.","Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies. ""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said. ""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption.""","The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ). Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men. Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women.","[3.0, 3.0, 4.0, 4.0, 5.0]",Biology,train,3.8,news,http://www.sciencedaily.com/releases/2014/08/140812121642.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41589-018-0155-8,Biology_148,"""The enhanced killer-T-cell activity we saw following ABHD12 deletion in the LCMV-infected mice suggests that blocking ABHD12 may enhance T-cell responses in immune suppressive environments such as chronic viral infections and cancers,"" Teijaro says.","6a) , and both groups of compound-treated animals also showed similar amounts of chemokines in BALF ( Supplementary Fig.","At the same time, treatments that target ABHD12, reducing its activity and stimulating the immune system, might have even broader use. ""The enhanced killer-T-cell activity we saw following ABHD12 deletion in the LCMV-infected mice suggests that blocking ABHD12 may enhance T-cell responses in immune suppressive environments such as chronic viral infections and cancers,"" Teijaro says. ""We're certainly eager to explore those possibilities,"" Cravatt says.","A similar fraction (~30-40%) of DO264-and (S)-DO271treated ABHD12 -/mice died before sacrifice at day 10, consistent with the response of ABHD12 -/mice to Cl13 infection in previous experiments (Fig. 6a) , and both groups of compound-treated animals also showed similar amounts of chemokines in BALF ( Supplementary Fig. 28 ).","[2.0, 1.0, 1.0, 1.0, 2.0]",Biology,train,1.4,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1016/j.cell.2018.04.034,Biology_149,This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment.,"At the transcriptional level, CDK12 mutant tumors are associated with over 300 DEGs, which makes them the most prominent molecular subtype in our analysis (Figures 2B and S4A) .","This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade. This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment. It could also explain why some prostate cancer patients have had exceptional responses to immunotherapy while the treatment has had lackluster results overall in prostate cancer.","Overall, the genomic phenotypes of HR and CDK12 deficiency are clearly distinct. At the transcriptional level, CDK12 mutant tumors are associated with over 300 DEGs, which makes them the most prominent molecular subtype in our analysis (Figures 2B and S4A) . Perhaps most importantly for translational purposes, CDK12 mutant cases exhibit a characteristic immunophenotype.","[2.0, 1.0, 2.0, 1.0]",Biology,train,1.5,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.3945/jn.113.188441,Biology_15,This association was found to be particularly strong for women.,"We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women.","4: Fried food

5: Fast food including instant noodles

Consumption of instant noodles is associated with an increased prevalence of metabolic syndrome

It was observed that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome in women which was independent of major dietary patterns. This association was found to be particularly strong for women. These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs.","As shown in previous reports, a high intake of refined carbohydrates such as white rice is known to increase the risk of type 2 diabetes, therefore nullifying the possible association between the MP and hyperglycemia in our study. We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women. Our findings suggest that instant noodle consumption alone might confer a higher cardiometabolic risk independent of overall dietary patterns.","[1.0, 3.0, 1.0, 2.0]",Biology,train,1.75,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.1016/j.neuron.2014.04.039,Biology_150,b-Amyloid Inhibits E-S Potentiation through Suppression of Cannabinoid Receptor1-Dependent Synaptic Disinhibition.,The present discovery of an explicit role for Ab in suppressing cannabinoid function elucidates a substrate of Alzheimer's pathology.,"Madison's group was surprised to see that in small, normal concentrations, beta-amyloid tamps down on the pyramidal nerve cells and blocks them from transmitting endocannabinoids. In other words, beta-amyloid appears to prevent these cells from passing along important information to other brain cells down the line. b-Amyloid Inhibits E-S Potentiation through Suppression of Cannabinoid Receptor1-Dependent Synaptic Disinhibition.","The mechanism by which Ab disables the effects of cannabinoids on synaptic inhibition, and thus disrupts plasticity, may explain learning and memory deficits in AD that occur in otherwise healthy neural circuits prior to AD-related neuronal cell death. The present discovery of an explicit role for Ab in suppressing cannabinoid function elucidates a substrate of Alzheimer's pathology. Thus, this newfound knowledge may advance understanding of the causes of Alzheimer's symptomatology and open new avenues for therapeutic intervention and improvement not only for memory in the earlier stages of the disease, but for the progression of the disease itself.","[4.0, 2.0, 2.0, 2.0, 2.0]",Biology,train,2.4,news,http://www.medicaldaily.com/if-blocked-endocannabinoids-trigger-dementia-symptoms-could-cannabis-prevent-alzheimers-288806
10.1016/j.cmet.2015.02.003,Biology_151,"That opens the possibility that salt may be an unrecognized contributor to the immune system, and possibly a remnant from the days before antibiotics, when mammals, including humans, needed some allies in the fight against microbes.",HSD-LysM,"The mice fed the higher amounts of sodium showed stronger immune responses to the wounds, and cleared their infections faster than the mice eating less salt. That opens the possibility that salt may be an unrecognized contributor to the immune system, and possibly a remnant from the days before antibiotics, when mammals, including humans, needed some allies in the fight against microbes. ""I really think salt is an unappreciated factor of immunity,"" says Jantsch.",HSD-control mice had significantly reduced L. major load in the skin ( Figure 4D ). HSD-LysM Cre Nfat5 fl/fl mice only showed a tendency (p = 0.058) toward L. major load reduction and tended to have higher L. major burden than controls (p = 0.078).,"[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,news,http://time.com/3730061/the-weird-benefit-of-eating-salty-food/
10.1016/j.immuni.2019.05.007,Biology_152,"The most important discovery of this study is a human antibody that can bind to a highly conserved region of the virus common among different strains of norovirus, potentially neutralizing all GII.4 strains of norovirus that exist in nature.",These findings suggest that the serological IgG response to human norovirus vaccination is largely dominated by the boosting of a limited number of pre-existing antibody clonotypes.,"""This information can now be used to build better human vaccines."" The most important discovery of this study is a human antibody that can bind to a highly conserved region of the virus common among different strains of norovirus, potentially neutralizing all GII.4 strains of norovirus that exist in nature. Highly conserved regions are parts of the virus that do not change.","The anti-GII.4c serological repertoire was predominantly comprised of antibodies using the immunoglobulin heavy variable 3 (IGHV3) family ($80%; Figure 1F ) compared to $30% in naive or mature B cells Mroczek et al., 2014) . These findings suggest that the serological IgG response to human norovirus vaccination is largely dominated by the boosting of a limited number of pre-existing antibody clonotypes. These included the top most abundant clonotypes in donors A and C (A379 and C601), two strongly boosted pre-existing clones (A101 and A1431, boosted by 123 and 1263, respectively, in terms of abundance in the post-vaccination serum relative to day 0), and six emergent antibodies ( Figure 1B .","[4.0, 3.0, 4.0]",Biology,train,3.6666666666666665,news,http://ct.moreover.com/?a=39490550792&p=1pl&v=1&x=jZsW-0WrF4cY8V2Qpk9zfA
10.1111/1365-2656.12871,Biology_155,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.","Relatively constant rates of RHDV-and MYXV-induced mortality and infection rates over time are likely to be the result of strongly coupled coevolutionary changes in host resistance and tolerance and pathogen invasiveness, each working to keep the other at bay.","""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","However, this is despite the viruses having devastating impacts on rabbit survival when the epidemics first occurred, likely because initial disease dynamics are often transient and differ from long-term outcomes ). Relatively constant rates of RHDV-and MYXV-induced mortality and infection rates over time are likely to be the result of strongly coupled coevolutionary changes in host resistance and tolerance and pathogen invasiveness, each working to keep the other at bay. It might be that virulence of both viruses in the study population is being maintained at an optimum (assuming that viruses track changes in host resistance as they are capable of fast selection and genetic changes due to fast replication), which is most efficient for viral spread.","[2.0, 4.0, 4.0]",Biology,train,3.333333333333333,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1038/s41467-018-08278-4,Biology_156,"If we are eventually to develop treatments to replace lost limbs, the BMP2 and BMP9 proteins may well have something to do with it.",Here we demonstrate that treating non-regenerative digit amputation wounds with BMP9 stimulates the regeneration of joint structures.,"It's a fascinating area of science, and we're learning a lot from lab-grown organs about how the process might be triggered more naturally. If we are eventually to develop treatments to replace lost limbs, the BMP2 and BMP9 proteins may well have something to do with it. ""These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation,"" conclude the researchers.","During joint development the formation of the synovial cavity is central to joint morphogenesis , and synovial cavity formation fails in digits that lack the BMP antagonist Noggin , suggesting that regulation of BMP signaling is required for joint morphogenesis. Here we demonstrate that treating non-regenerative digit amputation wounds with BMP9 stimulates the regeneration of joint structures. Further, we show that BMP9-induced joint regeneration requires the proteoglycan 4 (Prg4) gene.","[4.0, 4.0, 4.0, 3.0, 4.0]",Biology,train,3.8,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1038/s41467-017-01957-8,Biology_157,"Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off.","Thus, the prey diversity increases with an increasing m, which holds both for prey evolution and predator-prey coevolution.","In contrast, if the predator cannot adapt, the prey requires fewer resources for defence and can invest more in producing progeny"", explains Becks. Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off. The ciliates thus develop fewer different types in order to adapt to bacterial associations and biofilms.","When m increases, defense becomes cheaper and multiple prey types with different g values coexist (see Supplementary Figs. Thus, the prey diversity increases with an increasing m, which holds both for prey evolution and predator-prey coevolution. However, for a given m, the prey diversity is lower with coevolution ( Fig.","[2.0, 2.0, 2.0, 4.0, 1.0]",Biology,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.1016/j.stemcr.2018.03.019,Biology_158,"The differences between male and female iPS cells are most pronounced for one of the key processes in the field of epigenetics: DNA methylation, a modification that changes the activity of a DNA segment without changing its sequence.",Our study reveals that key regulatory regions associated with the control of cell identity genes are prone to changes in DNA methylation in reprogramming intermediates in both male and female cells.,"We now know that this explains the different behaviour of male and female cells after reprogramming because, over time, female cells lose one of the two X chromosomes and start behaving more or less like male iPS cells."" The differences between male and female iPS cells are most pronounced for one of the key processes in the field of epigenetics: DNA methylation, a modification that changes the activity of a DNA segment without changing its sequence. The researchers found that DNA methylations are erased in female iPS cells but not in male cells.","Nevertheless we found instances in which a single CpG within an ESC super-enhancer became hypomethylated in both female SSEA1 À and SSEA1 + intermediates, as well as in female iPSCs, but not in female MEFs, for example bordering the miR290-295 cluster ( Figure S4B ). Our study reveals that key regulatory regions associated with the control of cell identity genes are prone to changes in DNA methylation in reprogramming intermediates in both male and female cells. Nevertheless, we found that many CpGs, particularly those in enhancer elements, which are thought to play key roles for the maintenance of cell identity , change their methylation status earlier in reprogramming.","[5.0, 4.0, 4.0, 3.0, 3.0]",Biology,train,3.8,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1126/scitranslmed.3008325,Biology_160,"The rats walked more than 1,000 steps without failure, and could also climb staircases of various heights and lengths with fluid movements.","Animals with complete spinal cord injury performed more than 1000 successive steps without failure, and were able to climb staircases of various heights and lengths with precision and fluidity.","The investigators discovered a direct relationship between the frequency of electrical stimulation and how high rats lifted their limbs. The rats walked more than 1,000 steps without failure, and could also climb staircases of various heights and lengths with fluid movements. The scientists are planning a clinical trial that could start next summer to test such robot-assisted rehabilitation in patients with partially severed spinal cords.","These developments allowed us to conceive a neuroprosthetic system that controlled a broad range of foot trajectories during continuous locomotion in paralyzed rats. Animals with complete spinal cord injury performed more than 1000 successive steps without failure, and were able to climb staircases of various heights and lengths with precision and fluidity. Beyond therapeutic potential, these findings provide a conceptual and technical framework to personalize neuromodulation treatments for other neurological disorders.","[2.0, 4.0, 4.0, 4.0, 5.0]",Biology,train,3.8,news,http://www.popularmechanics.com/science/health/nueroscience/prosthetics-are-telling-paralyzed-leg-how-to-walk-again-17243055
10.1098/rstb.2008.0288,Biology_161,"It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets.","In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers.","In other words, taxi drivers had plumper memory centers than their peers. It seemed that the longer someone had been driving a taxi, the larger his hippocampus, as though the brain expanded to accommodate the cognitive demands of navigating London's streets. But it was also possible that The Knowledge selected for people whose memory centers were larger than average in the first place.","It may be that with a longer period of retirement, performance on tests such as the Rey Figure would normalize entirely. In line with the pattern of behavioural tests, it seems that the structural brain changes observed in taxi drivers in our previous studies may also reverse in retired taxi drivers. Full-time taxi drivers had significantly greater grey matter volume in the posterior hippocampus than retired taxi drivers, who had greater volume in this region than the non-taxi driver retired control participants (figure 6d ).","[2.0, 3.0, 4.0, 3.0, 2.0]",Biology,train,2.8,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.molcel.2014.05.030,Biology_162,"Besides regulating the amount of melanin that gets made in the skin, MC1R also controls how well melanocytes can repair their DNA from UV damage.",Pretreatment of cells with MSH reduced UV-induced mutagenesis in MC1R wild type cells but failed to affect mutation rates in MC1R mutant lines ( Figure 4A ).,"This leads to more UV light chronically getting through to the sensitive layers of the epidermis, where it can contribute to cancer. Besides regulating the amount of melanin that gets made in the skin, MC1R also controls how well melanocytes can repair their DNA from UV damage. Having defects in MC1R signaling delays the body's ability to clear out existing DNA damage in the skin -- leading to an increased potential for cancerous mutations.","MC1R mutant cell lines exhibited higher mutation rates when compared to MC1R wild-type cells. Pretreatment of cells with MSH reduced UV-induced mutagenesis in MC1R wild type cells but failed to affect mutation rates in MC1R mutant lines ( Figure 4A ). In contrast, forskolin pre-treatment suppressed UV-induced mutagenesis in every cell line tested, irrespective of MC1R status.","[2.0, 3.0, 2.0, 2.0, 2.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1405000111,Biology_164,"Previously, more species in the tropics led to the assumption that temperate, migratory species are derived from tropical, nonmigratory ancestors; however, the results of our phylogenetic study suggest that the opposite pattern happened often in this group.""","We also show that major lineages of tropical, sedentary emberizoids are derived from northern, migratory ancestors.","Another result of the study suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics year-round. ""This is an interesting result because species diversity in this group is much higher in the tropics. Previously, more species in the tropics led to the assumption that temperate, migratory species are derived from tropical, nonmigratory ancestors; however, the results of our phylogenetic study suggest that the opposite pattern happened often in this group.""","This result contrasts with a dominant paradigm that hypothesized migration evolving out of the tropics via shifts of the breeding ranges. We also show that major lineages of tropical, sedentary emberizoids are derived from northern, migratory ancestors. In these lineages, the winter ranges served as a biogeographic conduit for temperate-to-tropical colonization: winter-range shifts toward the tropics during the evolution of long-distance migration often preceded southward shifts of breeding ranges, the loss of migration, and in situ tropical diversification.","[4.0, 4.0, 3.0]",Biology,train,3.6666666666666665,news,http://www.sciencedaily.com/releases/2014/08/140804151419.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.3945/jn.113.188441,Biology_165,"""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption.""","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity.","""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said. ""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption."" Dr. Shin added that the study's health implications could be substantial - particularly if it leads to people choosing healthier foods.","Even though measurements of the glycemic index of instant noodles varied among studies , the overall glycemic load of instant noodles is high, given their high carbohydrate content ( ( . In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","[3.0, 4.0, 4.0, 2.0]",Biology,train,3.25,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1098/rsos.171474,Biology_168,"The task force also ""concluded that violent video game use is a risk factor for adverse outcomes, but found insufficient studies to examine any potential link between violent video game use and delinquency or criminal behavior.""",Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers.,"That task force ""found that violent video game exposure was associated with: an increased composite aggression score; increased aggressive behavior; increased aggressive cognitions; increased aggressive affect, increased desensitization, and decreased empathy; and increased physiological arousal."" The task force also ""concluded that violent video game use is a risk factor for adverse outcomes, but found insufficient studies to examine any potential link between violent video game use and delinquency or criminal behavior."" In Przybylski and Weinstein's review of prior literature, the two researchers strongly argue that earlier research is beset with such problems.","Keeping in mind the steps taken to ensure methodological rigour, the current results bear directly on the contentious literature surrounding games. Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers. Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours.","[5.0, 4.0, 4.0, 5.0, 2.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1016/j.cell.2018.04.034,Biology_17,Identifying specific mutation-associated neoantigens could thus feasibly lead to the development of personalized tumor vaccines.,"These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results.","Significantly, CDK12-mutated tumors also harbored higher numbers of surface neoantigens, which act to recruit immune-fighting T cells, a finding that may explain why this subtype of cancer is more susceptible to immune checkpoint blockade, and so why some patients do benefit from immune checkpoint blockade, the team suggests. Identifying specific mutation-associated neoantigens could thus feasibly lead to the development of personalized tumor vaccines. ""Perhaps most importantly for translational purposes, CDK12 mutant cases exhibit a characteristic immunophenotype....CDK12 mutant tumors show high overall immune infiltration, increased levels of tumor-infiltrating lymphotyces, and altered chemokine signalling.","In line with this possibility, high levels of CCL21 and CCL25 may mediate dendritic cell tumor trafficking and neoantigen-specific T cell clonal expansion (Chan et al., 1999; Gosling et al., 2000; . These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results. A plausible explanation is in the genetics of prostate cancer.","[4.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1016/j.cub.2018.06.016,Biology_170,"As the project progressed, fish were exposed to non-fish objects, which failed to initiate social orienting.",We conclude from these results that another socially engaged fish is the stimulus required for social orienting and that the presence of another fish that is not socially engaged is insufficient regardless of their proximity.,"Expecting to see behavioral disruptions in the drugged fish, which the researchers did, they also saw reduced orienting behaviors by the healthy fish. As the project progressed, fish were exposed to non-fish objects, which failed to initiate social orienting. Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting.","We placed apo-treated fish in a shortened tank that restricted their movement away from the divider and found that test fish exposed to apo-treated stimulus fish still had suppressed social orienting relative to controls (Figures  2A-2D ; p = 0.009, n = 26). We conclude from these results that another socially engaged fish is the stimulus required for social orienting and that the presence of another fish that is not socially engaged is insufficient regardless of their proximity. Orientation of the test fish and distance of the stimulus fish are highly correlated (R 2 = 0.302, p < 0.001), as is the orienting behavior of the stimulus fish (R 2 = 0.458, p < 0.001; Figures 2E and 2F ).","[4.0, 4.0, 4.0, 3.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=34657319504&p=1pl&v=1&x=IZljwk13voqosD3secxjLg
10.1016/j.cell.2018.04.034,Biology_171,"This could be a harbinger in early cancer,"" Chinnaiyan says.",Involved in the Cell Cycle and DNA Replication The large number of FTDs present in all CDK12 mutant tumors introduces the possibility of detecting synthetic genetic dependencies or epistasis.,"""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease. This could be a harbinger in early cancer,"" Chinnaiyan says. This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade.","Notably, the expression of BRCA1 or BRCA2 was not affected by CDK12 mutational status ( Figure S4J ) and neither was the expression of other genes encoding long transcripts and cognate proteins (Figure S4K) , a class previously suggested to be regulated by CDK12 (Blazek et al., 2011) . Involved in the Cell Cycle and DNA Replication The large number of FTDs present in all CDK12 mutant tumors introduces the possibility of detecting synthetic genetic dependencies or epistasis. Using both models, we detected a total of 27 loci with recurrent focal gains at false-discovery rates of 3.5% and 5%, respectively ( Figures 4A and S5C) .","[1.0, 3.0, 4.0, 1.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1111/1365-2656.12871,Biology_172,"Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","Overall, monthly survival rates of those rabbits immune to both diseases were 92% (CI 90-93%; corresponding to annual survival rates of 28%-43%).","""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute. ""The findings suggest a continuous benefit from both viruses and maximum impact on rabbit numbers if they act together.""","Young rabbits, including those with maternal antibodies to either virus, had significantly lower survival rates than immune rabbits in spring (Figure 2 and Supporting Information Figure S4 ), indicating that waning protection by antibodies result in infection and potentially, mortality, later in the same year. Overall, monthly survival rates of those rabbits immune to both diseases were 92% (CI 90-93%; corresponding to annual survival rates of 28%-43%). Survival rates did not differ between males and females (odds ratio male/female 0.97, CI: 0.85-1.14).","[2.0, 2.0, 3.0, 3.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1111/gcb.13526,Biology_173,"They attribute this boost in yield to increased photosynthesis, decreased respiration, and diversion of resources that would have been invested in more leaves than seeds.","The additional savings in roots could then be used to further increase seed yield, making our predicted yield increase estimates conservative.","They tested their prediction by removing about one third of the emerging leaves on soybeans and found an 8% increase in seed yield in replicated trials. They attribute this boost in yield to increased photosynthesis, decreased respiration, and diversion of resources that would have been invested in more leaves than seeds. ""This rate is insufficient to fulfill the needs for global food security, where we need to produce 70-100% more food by 2050 to feed an estimated 9.7 billion people,"" said project co-lead Steve Long, Gutgsell Endowed Professor of Plant Biology and Crop Sciences at the Carl R. Woese Institute for Genomic Biology at Illinois.","S7) , plants with lower LAI can potentially have fewer roots and save on root investment and maintenance costs. The additional savings in roots could then be used to further increase seed yield, making our predicted yield increase estimates conservative. Alternatively maintaining the same amount of root, yet decreasing transpiration demand, would make the crop more drought tolerant which will assume increasing importance across the Midwest as predicted climate change develops .","[2.0, 2.0, 5.0, 2.0, 4.0]",Biology,train,2.0,news,http://www.seeddaily.com/reports/Soybean_plants_with_fewer_leaves_yield_more_999.html
10.1111/1365-2656.12871,Biology_175,It shows that both myxoma (MYXV) and rabbit haemorrhagic disease (RHDV) viruses have worked together to control feral rabbit populations in Australia during the last two decades.,"We conclude that continuous, year-round virus perpetuation (and perhaps heterogeneity in modes of transmission and infectious doses during and after epidemics) acts to reduce the efficiency of RHDV and MYXV as biocontrol agents of rabbits","It shows that both myxoma (MYXV) and rabbit haemorrhagic disease (RHDV) viruses have worked together to control feral rabbit populations in Australia during the last two decades. ""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.","There was no evidence for long-term changes in disease-induced mortality and infection rates for either RHDV or MYXV. We conclude that continuous, year-round virus perpetuation (and perhaps heterogeneity in modes of transmission and infectious doses during and after epidemics) acts to reduce the efficiency of RHDV and MYXV as biocontrol agents of rabbits If the pathogen transmission process involves heterogeneity in the dosage of exposure/inoculum, the epidemiological dynamics can change fundamentally because of dose-dependent variation in mortality rates or variation of within-host replication of the pathogen and subsequent differences of transmission dynamics .","[5.0, 5.0, 3.0, 4.0, 1.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1111/gcb.13276,Biology_176,"""We want this index to be used to predict how corals might react to future bleaching events.","These standardizations are particularly important as the third pantropical bleaching event, which is expected to affect 38% of all reefs and kill >12 000 km of coral (www.globalcoralbleaching.org), is currently unfolding.","""Using very large data sets, we have teased out valuable information that will help researchers identify global trends and learn about individual corals,"" says coauthor Vadim Backman, professor of biomedical engineering. ""We want this index to be used to predict how corals might react to future bleaching events. The index will be available online, so that data on corals can be added as they become available, making the tool even more robust.","Furthermore, the effect of the uncertainty of bleaching measurement on differential bleaching of corals identified in this study (~29%) suggests that standardization of protocols and reporting would help increase the precision of susceptibility estimates and allow a global repository of standardized bleaching surveys. These standardizations are particularly important as the third pantropical bleaching event, which is expected to affect 38% of all reefs and kill >12 000 km of coral (www.globalcoralbleaching.org), is currently unfolding. Estimates of bleaching susceptibility are fundamental to assessing the resilience potential of reef sites, which can then be used to inform management decisions .","[3.0, 1.0, 4.0, 3.0]",Biology,train,2.75,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1038/s41467-018-07557-4,Biology_177,Findings showed that the thawing permafrost will pose a significant threat to Arctic communities across the Northern Hemisphere by 2050.,More information on the strengths and weaknesses of statistical techniques in analysing permafrost in a changing climate can be found in refs 23 .,"Findings showed that the thawing permafrost will pose a significant threat to Arctic communities across the Northern Hemisphere by 2050. ""We show that nearly four million people and 70 percent of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost,"" the team wrote. ""Our results demonstrate that one-third of pan-Arctic infrastructure and 45 percent of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment.","On the contrary, ice-rich sites close to the melting point can experience a more substantial time lag; however, these sites have high potential for ground subsidence regardless of temperature development because of an abundance of excess ice in the soil 37 . More information on the strengths and weaknesses of statistical techniques in analysing permafrost in a changing climate can be found in refs 23 . In brief, weather stations (n = 24,542) behind the data have relatively even spatial coverage (excluding Greenland) and the temperature and precipitation records have passed a quality control scheme.","[2.0, 2.0, 4.0, 2.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=37952048427&p=1pl&v=1&x=WVBbJHZ_CDGkehwcKPFvdQ
10.1111/1365-2656.12871,Biology_18,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.","Taken together, our results suggest that prolonged exposure of rabbits to RHDV (extending beyond seasonal outbreaks) and factors that cause variation in infection-induced mortality (such as variation in rabbit resistance to infection and virulence of the virus-the latter resulting potentially from variable modes and doses of infection) are among the likely mechanisms explaining the observed lower than expected mortality rate for RHDV at the study site.","""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","This is because we found (i) that individuals can potentially become infected after annual epidemics; (ii) that the force of RHDV infection oscillates over the year, leading to variation in the chances individuals become infected; and (iii) the average infection-induced mortality rate (69%) at Turretfield is lower than rates reported when RHD first spread (up to 95%; ). Taken together, our results suggest that prolonged exposure of rabbits to RHDV (extending beyond seasonal outbreaks) and factors that cause variation in infection-induced mortality (such as variation in rabbit resistance to infection and virulence of the virus-the latter resulting potentially from variable modes and doses of infection) are among the likely mechanisms explaining the observed lower than expected mortality rate for RHDV at the study site. We show that the two diseases have rather different effects on rabbit survival rates.","[3.0, 1.0, 1.0, 2.0, 2.0]",Biology,train,1.8,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1126/sciadv.1601660,Biology_181,"The key to printing tiny, precise, high-resolution patterns is in the amount of pressure applied to stamp the ink.","When this stamp is used to print, the excess ink spreads upon contact, resulting in greater width and corner roundness of the printed features compared to the stamp and an overall loss of pattern fidelity ( fig.","""The forests of carbon nanotubes can transfer ink onto a surface like massive numbers of tiny pen quills."" The key to printing tiny, precise, high-resolution patterns is in the amount of pressure applied to stamp the ink. ""We found, limited by the motor we used in the printing system, we could print at 200 millimeters per second, continuously, which is already competitive with the rates of industrial printing technologies.","However, we find that a slight amount of excess ink is present on the stamp surface. When this stamp is used to print, the excess ink spreads upon contact, resulting in greater width and corner roundness of the printed features compared to the stamp and an overall loss of pattern fidelity ( fig. When the CNT stamp is then used for printing, uniform ink transfer is achieved by relying on the formation of nanoscale contact points across the surface of each microscale stamp feature, therefore replicating the shapes of the stamp features with high accuracy.","[5.0, 5.0, 2.0, 4.0, 3.0]",Biology,train,3.8,news,http://news.mit.edu/2016/stamping-technique-printable-electronics-1207
10.1111/1365-2656.12871,Biology_185,"Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","If so, this has important implications for the use of these viruses as biocontrol agents for rabbits in their invasive range because these feedback processes carry long-term benefits for invasive species management, by maintaining negligible losses of virus virulence.","""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute. ""The findings suggest a continuous benefit from both viruses and maximum impact on rabbit numbers if they act together.""","It might be that virulence of both viruses in the study population is being maintained at an optimum (assuming that viruses track changes in host resistance as they are capable of fast selection and genetic changes due to fast replication), which is most efficient for viral spread. If so, this has important implications for the use of these viruses as biocontrol agents for rabbits in their invasive range because these feedback processes carry long-term benefits for invasive species management, by maintaining negligible losses of virus virulence. Our results suggest that heterogeneity in key factors such as mode and dose of virus transmission, and/or the infection process, may reduce the efficiency of RHDV as a biocontrol agent at the population level, independent of the virulence of the virus.","[3.0, 2.0, 4.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1098/rsos.171474,Biology_186,"""We found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games,"" they report.","As a result, we did not split data at an inflection point value or conduct the additional regression tests required to test if the nonlinear relationship between the time participants spends playing violent video games and aggression followed a step function like those found in other large-scale media effects research .","In Przybylski and Weinstein's review of prior literature, the two researchers strongly argue that earlier research is beset with such problems. ""We found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games,"" they report. Przybylski and Weinstein add, ""This pattern of findings further suggests that links reported in the literature might be influenced by publication bias, selective reporting, or an artefact of unobserved or hidden moderators.""","This was not possible because the parabolic term was not significant ( p ¼ 0.624), and as such we did not have an empirical basis to calculate the local extrema as planned. As a result, we did not split data at an inflection point value or conduct the additional regression tests required to test if the nonlinear relationship between the time participants spends playing violent video games and aggression followed a step function like those found in other large-scale media effects research . These results did not support the idea that there is a critical amount of violent video game play which serves as a tipping point for aggressive behaviour.","[3.0, 3.0, 3.0, 3.0, 1.0]",Biology,train,2.6,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1016/j.cell.2013.08.004,Biology_187,These drugs also might have broader therapeutic value for patients with mental health issues.,"Mirroring this molecular response, high-irradiance light pulses greater than 1 hr cease to have a phase-shifting effect upon the murine clock.","The findings reveal a little bit more about how our internal clocks function. In addition, the research could pave the way for drugs that could bring bodies in tune with the solar cycle more quickly. These drugs also might have broader therapeutic value for patients with mental health issues.","For example, under extended illumination, Per1 mRNA light-induction peaks after $1 hr and then returns to baseline , indicating CREB transcription is arrested one hour after it is induced. Mirroring this molecular response, high-irradiance light pulses greater than 1 hr cease to have a phase-shifting effect upon the murine clock. This saturation of the response suggests the presence of an unidentified negative-feedback mechanism that effectively limits the magnitude of phase-shifting responses to light within the SCN.","[1.0, 1.0, 1.0, 1.0, 2.0]",Biology,train,1.2,news,http://www.scienceworldreport.com/articles/9204/20130902/what-causes-jet-lag-internal-clock-slow-change-time.htm
10.1186/s40168-015-0071-z,Biology_188,"The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors.",It may be that the deficit in bifidobacteria that nonsecretor-fed infants experience is due to the likelihood of acquiring a species of bifidobacteria with metabolic abilities appropriate for the type of milk being consumed.,"The relationship between human genetics, breast milk and Bifidobacterium appears to have developed throughout mammalian evolution. The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors. The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota.","Understanding the mechanism behind these differences will prove crucial to potentially compensating for this problem, perhaps through carefully chosen prebiotics and/or probiotics. It may be that the deficit in bifidobacteria that nonsecretor-fed infants experience is due to the likelihood of acquiring a species of bifidobacteria with metabolic abilities appropriate for the type of milk being consumed. As modern hygiene standards and other cultural practices may lead to a reduction in the exposure levels to different bifidobacterial species, the phenomenon of the low bifidobacteria infant might be an artefact of developed countries.","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.180695,Biology_19,There was some variation in American responses.,North American homes were most similar in climate to the outdoor conditions of west central Kenya (C ¼ 2.938).,"The survey of U.S. indoor climate preferences in 37 states shows that, on average, Americans keep their home climate similar to the outdoor climate of northeast Africa, with outdoor conditions in west central Kenya the most similar to conditions in American homes. There was some variation in American responses. For example, citizens in North Carolina reported indoor conditions most like those in Namibia, which is in southern Africa and south of the equator.",The value distributions of the climate variables used in the climate dissimilarity index can be viewed in figure 1. North American homes were most similar in climate to the outdoor conditions of west central Kenya (C ¼ 2.938). The mean maximum temperature (average of all seasons) in the North American homes was 25.358C compared with 25.068C for the conditions outdoors in west central Kenya.,"[1.0, 4.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=38805436297&p=1pl&v=1&x=l29ocjlrSI4rkPLPT2Hygw
10.1098/rsos.180695,Biology_191,"Interestingly, citizen scientists in Alaska also reported indoor conditions most similar to those in Namibia.","When humans adjust the climates within their homes, it is unlikely that most are consciously attempting to emulate the climatic conditions of some outdoor location in another country or continent.","For example, citizens in North Carolina reported indoor conditions most like those in Namibia, which is in southern Africa and south of the equator. Interestingly, citizen scientists in Alaska also reported indoor conditions most similar to those in Namibia. ""Only three states reported indoor conditions that were most similar to non-African outdoor conditions.","The mean vapour pressure was 12.58 hPa for North American homes and was similar to the outdoor conditions in west central Kenya (12.96 hPa). When humans adjust the climates within their homes, it is unlikely that most are consciously attempting to emulate the climatic conditions of some outdoor location in another country or continent. Instead, they are almost certainly attempting to achieve climatic conditions that result in thermal comfort.","[3.0, 3.0, 2.0, 2.0, 3.0]",Biology,train,2.6,news,http://ct.moreover.com/?a=38805436297&p=1pl&v=1&x=l29ocjlrSI4rkPLPT2Hygw
10.1016/j.molcel.2014.05.030,Biology_192,Having defects in MC1R signaling delays the body's ability to clear out existing DNA damage in the skin -- leading to an increased potential for cancerous mutations.,", MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation .","Besides regulating the amount of melanin that gets made in the skin, MC1R also controls how well melanocytes can repair their DNA from UV damage. Having defects in MC1R signaling delays the body's ability to clear out existing DNA damage in the skin -- leading to an increased potential for cancerous mutations. ""If you happen to be born with a problem in this MC1R hormonal pathway, then you need to be extra careful with respect to UV safety.""","Together, these data identify that the Ser435 residue is a direct target of PKA and that its phosphorylation specifically enhances repair of UV-induced DNA damage. , MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation . Mediated by robust cAMP second messenger generation, MC1R signaling enhances the rate of clearance of UVinduced DNA photodamage .","[4.0, 4.0, 4.0, 3.0, 4.0]",Biology,train,3.8,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1405000111,Biology_193,Another result of the study suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics year-round.,"PlioPleistocene glaciations have clearly served to modify geographic ranges and migratory distances and routes and may have had an influence on more recent shifts of winter ranges out of North America in the Passerellidae (blue branches, Fig.","Tracing back through time and examining common ancestors of migratory and non-migratory species, they were able to conclude that there was more evidence supporting the idea that birds lived year-round in North America and began migrating further and further south, resulting in today's birds migrating thousands of miles every year. Another result of the study suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics year-round. ""This is an interesting result because species diversity in this group is much higher in the tropics.","As such, early shifts of winter ranges may not represent invasions of tropical habitats as much as tracking of tropical habitat to lower latitudes to escape harsh winter conditions while maintaining breeding at high latitudes ( . PlioPleistocene glaciations have clearly served to modify geographic ranges and migratory distances and routes and may have had an influence on more recent shifts of winter ranges out of North America in the Passerellidae (blue branches, Fig. 4) .","[1.0, 2.0, 3.0, 1.0]",Biology,train,1.75,news,http://www.sciencedaily.com/releases/2014/08/140804151419.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1405000111,Biology_194,The first is that ancestors of migratory birds spent the whole year in North America and evolved migration by moving their winter range to the tropics.,Our results further suggest that seasonal migration promoted colonization of the tropics from North America.,"The first is that ancestors of migratory birds spent the whole year in North America and evolved migration by moving their winter range to the tropics. Eventually, they found that more evidence supported the idea that birds once lived year-round in North America and eventually began migrating further and further south, resulting in today's migrations. This also suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics.","Contrary to expectations, we found that long-distance migration primarily evolved through evolutionary shifts of geographic range south for the winter out of North America, as opposed to north for the summer. Our results further suggest that seasonal migration promoted colonization of the tropics from North America. We found that seasonal migration between breeding ranges in North America and winter ranges in the Neotropics evolved primarily via shifts of winter ranges toward the tropics from ancestral ranges in North America.","[4.0, 5.0, 3.0, 1.0]",Biology,train,4.0,news,http://www.scienceworldreport.com/articles/16439/20140805/bird-migration-first-evolved-songbirds-fled-cold-north.htm
10.14814/phy2.13617,Biology_195,"""We know younger individuals have larger pupils, and their lenses are more transparent.","Still, our findings of robust melatonin suppression in this age group call for an understanding of the effects of lightemitting electronic devices on the circadian physiology of young children.","Direct comparisons between this study and studies in adults must be made with caution because of differing research protocols, the researchers stress. ""We know younger individuals have larger pupils, and their lenses are more transparent. This heightened sensitivity to light may make them even more susceptible to dysregulation of sleep and the circadian clock.""","Although the 1000 lux stimulus administered in this study would be similar to a brightly lit environment, it is not comparable to the intensity of light emitted from electronic devices (~30-50 lux; ). Still, our findings of robust melatonin suppression in this age group call for an understanding of the effects of lightemitting electronic devices on the circadian physiology of young children. Findings from our laboratory indicate that the natural increase in endogenous melatonin in well-controlled dim light conditions occurs~50-min before bedtime (i.e., bedtime phase angle; interval between melatonin onset and bedtime) in young children ).","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://healthmedicinet.com/news/preschoolers-exposed-to-nighttime-light-lack-melatonin/
10.1016/j.celrep.2016.08.013,Biology_196,"This repeating cycle allowed the bacteria to stably move over the endothelial surface at a constant overall speed, similar to the way immune cells called leukocytes move through blood vessels.","Therefore, counterintuitively, the small size of bacteria made them less sensitive to force and torque imposed by flow than leukocytes.","Similar to children swinging on monkey bars, the bacteria transferred force from one bond to the next without fully detaching, slowing down every time they established a new bond and accelerating when they broke a bond and transitioned to the next one. This repeating cycle allowed the bacteria to stably move over the endothelial surface at a constant overall speed, similar to the way immune cells called leukocytes move through blood vessels. Additional calculations revealed that the propulsive force generated by bacterial motility is stronger than the forces imposed on bacteria by flow, suggesting that the microbes may use rotating internal structures called flagella to actively migrate along blood vessel walls and exit the vasculature to reach specific tissues, even under the force conditions generated by blood flow.","Average F s and T s experienced by bacteria were at least 10 times smaller than F s and T s experienced by rolling leukocytes at similar shear stresses , due to the relatively small B. burgdorferi radius. Therefore, counterintuitively, the small size of bacteria made them less sensitive to force and torque imposed by flow than leukocytes. Since most bacteria are as small or smaller than B. burgdorferi, this conclusion is likely to be true for other bacteria.","[3.0, 4.0, 1.0, 2.0]",Biology,train,2.5,news,https://www.sciencedaily.com/releases/2016/08/160825130027.htm
10.1016/j.cell.2015.07.058,Biology_197,"And when both threats to the genome are present, MRN will activate the massive response at the DNA break; no MRN is left to respond to the virus.",These data demonstrate that the binding of MRN and activation of a localized ATM response prevents viral genome replication.,"If every incoming virus spurred a similarly strong response, points out O'Shea, our cells would be frequently paused, hampering our growth. And when both threats to the genome are present, MRN will activate the massive response at the DNA break; no MRN is left to respond to the virus. This means the virus is effectively ignored while the cell responds to the more massive alarm.","Similar conclusions were obtained with doxorubicin treatment (Figure S6E ). These data demonstrate that the binding of MRN and activation of a localized ATM response prevents viral genome replication. Furthermore, the induction of cellular DNA breaks sequesters MRN and prevents the restriction of viral replication.","[3.0, 3.0, 1.0, 1.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1016/j.cell.2018.04.034,Biology_198,Identifying specific mutation-associated neoantigens could thus feasibly lead to the development of personalized tumor vaccines.,FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication.,"Significantly, CDK12-mutated tumors also harbored higher numbers of surface neoantigens, which act to recruit immune-fighting T cells, a finding that may explain why this subtype of cancer is more susceptible to immune checkpoint blockade, and so why some patients do benefit from immune checkpoint blockade, the team suggests. Identifying specific mutation-associated neoantigens could thus feasibly lead to the development of personalized tumor vaccines. ""Perhaps most importantly for translational purposes, CDK12 mutant cases exhibit a characteristic immunophenotype....CDK12 mutant tumors show high overall immune infiltration, increased levels of tumor-infiltrating lymphotyces, and altered chemokine signalling.",CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion. FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication. CDK12 mutant cases are baseline diploid and do not exhibit DNA mutational signatures linked to defects in homologous recombination.,"[1.0, 3.0, 2.0, 1.0, 1.0]",Biology,train,1.6,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.3945/jn.113.188441,Biology_199,"""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption.""",Our findings suggest that instant noodle consumption alone might confer a higher cardiometabolic risk independent of overall dietary patterns.,"""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said. ""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption."" Dr. Shin added that the study's health implications could be substantial - particularly if it leads to people choosing healthier foods.","We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women. Our findings suggest that instant noodle consumption alone might confer a higher cardiometabolic risk independent of overall dietary patterns. The combined effect of high energy density (381-464 kcal/100 g) , high glycemic loads with refined carbohydrates, high saturated fat content (66.2-87.2 kcal/100 g) , and high sodium (1.7-2.5 g/serving) may contribute to an increased risk of metabolic syndrome and abdominal obesity.","[3.0, 3.0, 3.0, 4.0]",Biology,train,3.25,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1186/s13578-015-0003-4,Biology_2,These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.,Our study indicates an important role of H 2 S in protecting against the aging cardiovascular disease.,"LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts. These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.","The mRNA and protein levels of CSE are decreased in the lenses from old rats, and inhibition of CSE activity leads to cataractogenesis in vitro . Our study indicates an important role of H 2 S in protecting against the aging cardiovascular disease. KH buffer comprised (in mmol/L): NaCl 118, KCl 4.7, MgSO 4 1.2, KH 2 PO 4 1.2, CaCl 2 2.5, NaHCO 3 25, and glucose 11 at pH 7.4.","[5.0, 5.0, 1.0, 5.0, 5.0]",Biology,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1016/j.cell.2018.04.038,Biology_201,"""We have very deep insights into how telomerase works and how the components work together,"" Susac said.","All telomerases contain a catalytic core of TERT and TER, which are sufficient to reconstitute activity in vitro.","This new research brings this goal closer to reality by providing clues about what parts to target. ""We have very deep insights into how telomerase works and how the components work together,"" Susac said. ""Each of these interactions could be a point to target, and possibly disrupt or enhance the function of telomerase.","The cryo-EM structure of active Tetrahymena telomerase bound to telomeric DNA reveals unique insights into the catalytic core and DNA handling. All telomerases contain a catalytic core of TERT and TER, which are sufficient to reconstitute activity in vitro. The other seven proteins, p50, and two heterotrimeric replication protein A (RPA) related complexes, Teb1-Teb2/Rpa2-Teb3/Rpa3 (TEB) ) and p75-p45-p19 (Tetrahymena CTC1-STN1-TEN1 [CST]) , are paralogous to human proteins that only transiently associate with telomerase .","[4.0, 3.0, 2.0, 3.0, 3.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1016/j.cell.2015.07.058,Biology_203,"The MRN response to the virus stays localized and only selectively prevents viral, but not cellular, replication.","In WT-virus-infected cells, neither MR knockdown nor Mirin prevents the global phosphorylation of DDR substrates ( Figure 2C ).","The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell. The MRN response to the virus stays localized and only selectively prevents viral, but not cellular, replication. If every incoming virus spurred a similarly strong response, points out O'Shea, our cells would be frequently paused, hampering our growth.","However, similar to SAECs, the levels of virus genomes are 10 4 times higher in WT versus DE1B-55K/DE4-ORF3-infected A549 cells ( Figure 2B ). In WT-virus-infected cells, neither MR knockdown nor Mirin prevents the global phosphorylation of DDR substrates ( Figure 2C ). Thus, the activation of global DDR signaling in WT-virus-infected cells is MRN independent and is not due to residual MRN expression or activity.","[1.0, 3.0, 3.0, 1.0, 1.0]",Biology,train,1.8,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1073/pnas.1405000111,Biology_204,"""This is an interesting result because species diversity in this group is much higher in the tropics,"" said Rick Ree, one of the researchers, in a news release.","Thus, early shifts of winter ranges (e.g., starred node, Fig.","This also suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics. ""This is an interesting result because species diversity in this group is much higher in the tropics,"" said Rick Ree, one of the researchers, in a news release. ""Previously, more species in the tropics led to the assumption that temperate, migratory species are derived from tropical, nonmigratory ancestors; however, the results of our phylogenetic study suggest that the opposite pattern happened often in this group.""","4) , and age estimates for major emberizoid lineages date as far back as the early Miocene , with the split from the sister family to Emberizoidea, the cosmopolitan Fringillidae, dated to the late Oligocene (20-25 MyBP) . Thus, early shifts of winter ranges (e.g., starred node, Fig. 4 ) may have occurred in response to global cooling and increasing seasonality at high latitudes since the late Oligocene .","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.scienceworldreport.com/articles/16439/20140805/bird-migration-first-evolved-songbirds-fled-cold-north.htm
10.1186/s40168-015-0071-z,Biology_205,The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy.,"Of the 70 milks from secretor women, 23 of the matched infant stool samples were Low-Bif qPCR (32.9%).","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","Of 35 milks from non-secretors, 20 of the matched infant stool samples were Low-Bif qPCR (57.1%). Of the 70 milks from secretor women, 23 of the matched infant stool samples were Low-Bif qPCR (32.9%). A Pearson chi-square test was significant (p = 0.0171), indicating that mother's secretor status and infant bifidobacteria levels are dependent variables.","[2.0, 1.0, 3.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1534/genetics.116.197285,Biology_206,"""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said.","Possible outcomes can include the fixation of the driver, loss of the driver, and both stable or unstable equilibria, depending on the cleavage rate, c, the fitness costs of the driver allele, s dd and s d0 , and the initial frequency x d (t = 0) at which the driver is introduced into the population.","Yet, faced with the new and sophisticated CRISPR/Cas9 method of gene drive, nature is still likely to fight back to resist the mutation successfully, Unckless said. ""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said. They show nature still has the edge over scientists hoping to solve human problems with GM organisms.","However, we can also use these equations to specify expected values in Wright-Fisher-type simulations that explicitly incorporate random genetic drift. Possible outcomes can include the fixation of the driver, loss of the driver, and both stable or unstable equilibria, depending on the cleavage rate, c, the fitness costs of the driver allele, s dd and s d0 , and the initial frequency x d (t = 0) at which the driver is introduced into the population. Briefly, in scenarios with high cleavage rate and small fitness costs, the driver will usually fix even when introduced at low 2 .","[1.0, 2.0, 3.0, 2.0, 1.0]",Biology,train,1.8,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1111/1365-2656.12871,Biology_207,"""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result.","As IgM is the first antibody to appear in response to initial exposure to RHDV , it confirms a likely annual persistence of RHDV at low levels in the rabbit population at Turretfield.","It shows that both myxoma (MYXV) and rabbit haemorrhagic disease (RHDV) viruses have worked together to control feral rabbit populations in Australia during the last two decades. ""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.","Our finding that RHDV can persist at low levels across the year is independently supported by relatively short-lived immunoglobulin M (IgM), being detected (at titres ≥40) in low numbers of rabbits throughout the year (Supporting Information Figure S10 ). As IgM is the first antibody to appear in response to initial exposure to RHDV , it confirms a likely annual persistence of RHDV at low levels in the rabbit population at Turretfield. Alternatively, lower abundance of virus-carrying flies may result in lower abundance of virus particles in the environment, which, in turn, may lead to low dose contraction.","[1.0, 2.0, 4.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1186/s13059-018-1434-0,Biology_209,"We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer.","In other words, we expect that mutations strongly altering protein function in a gene under negative selection would be removed from the host genetic pool because they will hinder tumor proliferation and thus these genes will only tolerate low or no functional impact mutations.","""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes. We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer. ""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities.""","Nevertheless, the other four significant genes found by CBaSe, and not found by SSB-d N /d S , had SSB-d N /d S values smaller than one. In other words, we expect that mutations strongly altering protein function in a gene under negative selection would be removed from the host genetic pool because they will hinder tumor proliferation and thus these genes will only tolerate low or no functional impact mutations. We observed that genes displaying a low SSB-d N /d S ratio (from now on d N /d S , unless otherwise specified) were depleted in high functional impact mutations compared to those of neutral and positively selected genes (see Fig.","[3.0, 2.0, 4.0, 3.0, 2.0]",Biology,train,2.8,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1016/j.cell.2018.04.034,Biology_21,This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment.,"Intriguingly, in both cases, the genomic instability engendered by the deficiency becomes a ''doubleedged sword.''","This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade. This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment. It could also explain why some prostate cancer patients have had exceptional responses to immunotherapy while the treatment has had lackluster results overall in prostate cancer.","CDK12 inactivation thereby defines a distinct class of mCRPC that may benefit from immune checkpoint immunotherapy. Intriguingly, in both cases, the genomic instability engendered by the deficiency becomes a ''doubleedged sword.'' For example, cancer cells with MMRD have a high mutation burden that generates tumor neoantigens, thereby making the patients favorable candidates for intervention with immunotherapies .","[2.0, 1.0, 1.0, 3.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1002/emmm.201302567,Biology_210,The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.,"Although basal SMN levels are below normal, due to the mouse genotype, SMN is further reduced in a tissue-specific manner, by ASO treatment, which is distinct from the situation in SMA patients.","Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA. How much a patient is helped depends on the number of copies of the SMN2 gene they possess.","Except for the tail and ear necrosis, our model has an asymptomatic phase before disease onset at the adult stage, as seen in type IV SMA. Although basal SMN levels are below normal, due to the mouse genotype, SMN is further reduced in a tissue-specific manner, by ASO treatment, which is distinct from the situation in SMA patients. The disease progression after onset in our model is more acute, and without chronic compensation.","[1.0, 4.0, 3.0, 2.0]",Biology,train,2.5,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1038/nature24621,Biology_211,"Within this first release of data, the Earth Microbiome Project team identified around 300,000 unique microbial 16S rRNA sequences, almost 90 percent of which don't have exact matches in pre-existing databases.","While earlier largescale 16S rRNA amplicon studies adopted OTU clustering approaches in part out of concern that erroneous reads would dominate diversity assessments 23 , patterns of prevalence (presenceabsence) in our results suggest that Deblur error removal produced ecologically informative sequences without clustering.","That could be useful forensic information at a crime scene,"" he says. Within this first release of data, the Earth Microbiome Project team identified around 300,000 unique microbial 16S rRNA sequences, almost 90 percent of which don't have exact matches in pre-existing databases. Now, we have a framework that supports all that additional context, and which can grow organically to support new kinds of questions and insights.""","Because exact sequences are stable identifiers, unlike OTUs, they can be compared to any 16S rRNA or genomic data base now and in the future, thereby promoting reusability 22 . While earlier largescale 16S rRNA amplicon studies adopted OTU clustering approaches in part out of concern that erroneous reads would dominate diversity assessments 23 , patterns of prevalence (presenceabsence) in our results suggest that Deblur error removal produced ecologically informative sequences without clustering. After rarefying to 5,000 sequences per sample, a total of 307,572 unique sequences were contained in the 96 studies and 23,828 samples of the 'QCfiltered' Deblur 90bp observation table.","[3.0, 2.0, 4.0, 2.0]",Biology,train,2.75,news,http://www.futurity.org/earth-microbiome-project-1595972/
10.1038/s41467-018-07557-4,Biology_212,"Planners and engineers need to know in detail where permafrost is most likely to thaw as they plan for replacements, upgrades and maintenance.","In an engineering context, the selected threshold is conservative because infrastructure (e.g., buildings) could experience thaw settlements and failure before the thaw of near-surface permafrost.","However, after 2050, attaining the Paris Agreement goals would make a clear difference in potential damage to infrastructure. They note that because of the uncertainties, the amount of infrastructure at risk from permafrost thaw is probably not much smaller than their estimate, but could be substantially larger. Planners and engineers need to know in detail where permafrost is most likely to thaw as they plan for replacements, upgrades and maintenance.","The ensemble model provided accurate predictions of the observed ground temperatures retrospectively, indicating potential for good performance in prognostic studies 23 . In an engineering context, the selected threshold is conservative because infrastructure (e.g., buildings) could experience thaw settlements and failure before the thaw of near-surface permafrost. However, a conservative threshold is justified considering the use of statistically based methodology in modelling of the ground thermal regime (Methods).","[2.0, 2.0, 4.0, 3.0]",Biology,train,2.75,news,http://ct.moreover.com/?a=37952353365&p=1pl&v=1&x=z8k6aIsKNtvV0TWFOzO7Gg
10.1016/j.molcel.2014.05.030,Biology_213,"""If you tend to burn, then you may have inherited a problem with your MC1R, and you probably should avoid purposeful UV exposure like tanning bed use or unprotected sun exposure.""","Furthermore, UV damage alone did not promote production of cAMP ( Figure S2E ), suggesting that in the skin UVassociated melanocytic cAMP increases depend on an intact MC1R signaling pathway initiated by MSH.","""If you tan well, then your MC1R probably works well,"" D'Orazio said. ""If you tend to burn, then you may have inherited a problem with your MC1R, and you probably should avoid purposeful UV exposure like tanning bed use or unprotected sun exposure."" D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study.","However, forskolin enhanced clearance of both [6-4]-PP and CPD in all melanocyte cells tested regardless of MC1R status (Figures 1E and 1F) with no apparent effect on cell proliferation ( Figure S2) indicating photolesion clearance was not influenced by proliferative differences. Furthermore, UV damage alone did not promote production of cAMP ( Figure S2E ), suggesting that in the skin UVassociated melanocytic cAMP increases depend on an intact MC1R signaling pathway initiated by MSH. Interestingly, cAMP-enhanced repair was not limited to melanocytic lines, as a repair benefit was also observed in .","[3.0, 3.0, 1.0, 2.0, 5.0]",Biology,train,4.0,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.171474,Biology_215,"Their top-line finding is that their study ""did not support the position that violent gaming relates to aggressive behaviour.""","Indeed, statistical significance does not necessitate a subjective state that humans can distinguish on a personal level .","The title lays it out plainly: ""Violent video game engagement is not associated with adolescents' aggressive behaviour."" Their top-line finding is that their study ""did not support the position that violent gaming relates to aggressive behaviour."" This contradicts the consensus hammered out by an American Psychological Association task force on violent video games in 2017.","We believe the current work is the second study in the area to set the number of observations based on an a priori power analysis , and the first to specify a minimum effect size of theoretical interest. Indeed, statistical significance does not necessitate a subjective state that humans can distinguish on a personal level . Given interactive media and their effects are inherently subjective, we believe working toward adoption of a new standard for interpreting the practical significance of media effects would serve the literature well as a benchmark against which putative effects of emergent technologies such as virtual reality, augmented reality and artificial intelligence may be judged.","[2.0, 1.0, 1.0, 2.0]",Biology,train,1.5,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1016/j.stemcr.2018.03.019,Biology_217,"So the female iPS cells now have two active X chromosomes, while males have only one.","Together, these results indicate that imprints are not only erased in XX iPSCs but also are not re-established upon global genome remethylation in XO iPSCs, which suggests that female iPSCs, regardless of the number of Xas, may have a similarly poor developmental potential as female ESCs .","But when these cells are reprogrammed into iPS cells, the inactive X becomes active. So the female iPS cells now have two active X chromosomes, while males have only one. We now know that this explains the different behaviour of male and female cells after reprogramming because, over time, female cells lose one of the two X chromosomes and start behaving more or less like male iPS cells.""","Here, we found evidence of imprint erasure for the imprint control region of Zrsr1 in female XX and XO iPSCs (Table S2) . Together, these results indicate that imprints are not only erased in XX iPSCs but also are not re-established upon global genome remethylation in XO iPSCs, which suggests that female iPSCs, regardless of the number of Xas, may have a similarly poor developmental potential as female ESCs . Interestingly, we found that within several of these cis-regulatory regions, changes in average methylation levels were already apparent in both SSEA1 subpopulations, and more pronounced in XaXa iPSCs (Figures 3D-3G) .","[3.0, 3.0, 2.0, 3.0, 1.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1016/j.cell.2018.04.034,Biology_221,"This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy.""",Pre-treatment PSA prior to initiation of immunotherapy was 628.8 ng/mL with a modest improvement in PSA after three doses of anti-PD-1 and subsequent PSA decline to 599.2 ng/mL.,"""The fact that immune checkpoint inhibitors may be effective against this subtype of prostate cancer makes it even more significant. This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy."" They identified CDK12 mutations in 25/360 mCRPC patients (6.9%), but in only 6/498 patients with primary prostate cancer.","Patient MO_2017 had heavily pre-treated disease, with prior disease progression on abiraterone, enzalutamide, docetaxel, and cabazitaxel. Pre-treatment PSA prior to initiation of immunotherapy was 628.8 ng/mL with a modest improvement in PSA after three doses of anti-PD-1 and subsequent PSA decline to 599.2 ng/mL. Evaluation of a metastatic lymph node biopsy demonstrated robust CD3 staining by IHC ( Figure 7B ).","[1.0, 1.0, 1.0, 3.0, 2.0]",Biology,train,1.6,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1210/en.2015-2036,Biology_223,"Further studies are warranted, but this direct association between vitamin D levels and ID1 expression is very interesting to us.""","Significantly, our results demonstrate that, in BCa cells, VDR regulation of ID1 expression is mechanistically conserved in humans and that there is a negative association between circulating 25(OH)D levels and the expression of ID1 in primary tumors from BCa patients.","They found an inverse correlation: Women with lower levels of vitamin D expressed more ID1 in their tumor tissues than did women with higher levels of vitamin D.

""Our study shows that a deficiency in vitamin D levels, or an inability of tumor cells to respond appropriately to the presence of vitamin D, is sufficient to trigger non-metastatic cancer cells to become metastatic,"" said Feldman. ""It's enough to significantly accelerate tumor progression in our mouse model. Further studies are warranted, but this direct association between vitamin D levels and ID1 expression is very interesting to us.""","These distinctions with our study indicate that vitamin D signaling is highly context specific. Significantly, our results demonstrate that, in BCa cells, VDR regulation of ID1 expression is mechanistically conserved in humans and that there is a negative association between circulating 25(OH)D levels and the expression of ID1 in primary tumors from BCa patients. We believe these findings contribute to the cause of the epidemiological association between low circulating 25(OH)D levels and poor prognosis in patients with BCa.","[2.0, 3.0, 4.0, 3.0]",Biology,train,3.0,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1002/emmm.201302567,Biology_225,"Hence the importance of the team's success, reported online today in EMBO Molecular Medicine.","In adult mice with Smn-null background, the SMN levels required for normal CNS function correspond to an SMN2 copy number less than two, suggesting that only moderate SMN levels are necessary for therapy in adult-onset SMA.","(click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults. Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.","Compared with neonatal administration, this procedure elicited late-onset motor phenotypes. In adult mice with Smn-null background, the SMN levels required for normal CNS function correspond to an SMN2 copy number less than two, suggesting that only moderate SMN levels are necessary for therapy in adult-onset SMA. The effects of peripheral SMN2 missplicing induced by TSUNAMI highlight the potential importance of specific pathogenesis in the liver and heart.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1016/j.neuron.2014.05.028,Biology_227,"Thus, the trauma and its circumstances are remembered but the consolidation of fear memories is impaired, which could decrease the likelihood of developing fear-related disorders,"" Andero says.","Thus, given the lack of colocalization and regional and functional specificity of these cell populations, we have uncovered a subdivision-specific cell population that may be involved in the consolidation of fear memory.","""Osanetant is a safe and well-tolerated drug in humans and could be potentially used to prevent PTSD when given shortly after trauma, although more research is needed,"" Andero says. Under the influence of osanetant, mice could still learn to become afraid of a sound paired with a shock, but the mice did not freeze as much in response to the sound a day later, even if the drug was given an hour after training. Thus, the trauma and its circumstances are remembered but the consolidation of fear memories is impaired, which could decrease the likelihood of developing fear-related disorders,"" Andero says.","Using double fluorescent in situ hybridization (FISH), we show that Tac2 gene expression is mostly not colocalized with PKCd or Enk and is expressed primarily within the CeM (Figures 2A-2F ). Thus, given the lack of colocalization and regional and functional specificity of these cell populations, we have uncovered a subdivision-specific cell population that may be involved in the consolidation of fear memory. Moreover, NkB peptide is also highly expressed in the CeA ( Figure 3B ).","[1.0, 2.0, 3.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-07557-4,Biology_228,"There's No Silver Lining

To make matters worse, the study also notes that these drastic changes will still happen even if the world decreases its carbon emission significantly.","Considering different stabilization scenarios of climate warming, our analysis reveals that substantial cuts in global greenhouse gas (GHG) emissions now would not make a large difference for infrastructure risks in the highest hazard area by 2050.","There's No Silver Lining

To make matters worse, the study also notes that these drastic changes will still happen even if the world decreases its carbon emission significantly. The new findings revealed ""an unprecedentedly high spatial resolution"" perspective of how permafrost will jeopardize infrastructure. The findings also showed that one-third of all Arctic infrastructure rests on a piece of land that is highly likely to thaw by 2050.","For example, our results highlight critical areas such as the Pechora region, the northwestern parts of the Ural Mountains, northwest and central Siberia, the Yakutsk basin (except for the city of Yakutsk in low to moderate hazard area), as well as the central and western parts of Alaska to which high priority for local scale infrastructure hazard assessments should be performed in future decades 1 . Considering different stabilization scenarios of climate warming, our analysis reveals that substantial cuts in global greenhouse gas (GHG) emissions now would not make a large difference for infrastructure risks in the highest hazard area by 2050. This is because nearly the same number of buildings, roads, and other infrastructure would be jeopardized under moderate climate warming (RCP2.6) as compared to a pessimistic, business-asusual scenario (RCP8.5) ( Fig.","[3.0, 2.0, 3.0, 4.0, 5.0]",Biology,train,3.4,news,http://ct.moreover.com/?a=37967333906&p=1pl&v=1&x=ltio0H7-Rr6r3LuvSX7DEA
10.3945/jn.113.188441,Biology_23,This association was found to be particularly strong for women.,"The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","4: Fried food

5: Fast food including instant noodles

Consumption of instant noodles is associated with an increased prevalence of metabolic syndrome

It was observed that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome in women which was independent of major dietary patterns. This association was found to be particularly strong for women. These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs.","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age. Our study had several limitations.","[3.0, 1.0, 2.0]",Biology,train,2.0,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.1038/srep01456,Biology_230,"""Bed bugs evolved unique adaptive strategy to resist pyrethroid insecticides.""",The P450s or Abc8 and Abc9 knockdown in pyrethroid resistant CIN-1 S bed bugs showed a consistent increase in their susceptibility to bcyfluthrin compared with control bed bugs injected with malE dsRNA (Fig.,"Sometimes, in the face of chemical and genetic trickery, brute force turns out to work best. SOURCE: Zhu et al. ""Bed bugs evolved unique adaptive strategy to resist pyrethroid insecticides.""","CIN-1 S bed bugs are highly resistant to deltamethrin, with a high topical dose leading to no mortality. The P450s or Abc8 and Abc9 knockdown in pyrethroid resistant CIN-1 S bed bugs showed a consistent increase in their susceptibility to bcyfluthrin compared with control bed bugs injected with malE dsRNA (Fig. In contrast, there was no significant difference in the susceptibility to b-cyfluthrin between cuticular proteins knockdown and control bed bugs (Fig.","[2.0, 4.0, 5.0, 2.0]",Biology,train,5.0,news,http://www.ibtimes.com/bedbugs-foil-pesticides-special-adaptations-their-armor-1403721
10.1016/j.cmet.2015.02.003,Biology_231,The diet enabled an increased concentration of salt at the source of infection and allowed the mice to rid themselves of the infection more quickly than those that did not receive a high-salt diet.,We found that Na + accumulated at the site of bacterial skin infections in humans and in mice.,"After treating the patients with antibiotics, the salt accumulation disappeared along with the infection. The diet enabled an increased concentration of salt at the source of infection and allowed the mice to rid themselves of the infection more quickly than those that did not receive a high-salt diet. But researchers said their findings don't translate to a recommendation for increased salt intake.",We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control.,"[2.0, 2.0, 3.0, 4.0, 2.0]",Biology,train,2.6,news,http://www.upi.com/Science_News/2015/03/03/Scientists-say-salt-may-guard-against-infection/4511425414509/
10.1038/s41467-019-09863-x,Biology_232,"""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost.",Robustness of the estimates for the PCF and SAF effects.,"What's needed, he said, is urgency and political will. ""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost. But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev.","The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 . Robustness of the estimates for the PCF and SAF effects. Other major feedbacks implemented in the fully-coupled GCMs such as clouds, water vapour and lapse rate contribute to overall uncertainty and state-dependency in the ECS parameter 35 .","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1038/s41589-018-0155-8,Biology_233,"Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so.",We found evidence for a similar mechanism of action in ABHD12 -/mice in which antiviral CD8 T cells from these animals displayed increased killing capacity compared to cells from ABHD12 +/+ mice in both spleen and lung ( Fig.,"Ordinary mice infected with LCMV clone 13 typically have minor symptoms but take a long time to clear the infection. Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so. advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says.","The lung pathology caused by restoration of T cell function, for instance, by anti-PD-1 antibodies during persistent Cl13 infection depends on CD8 T cell-mediated killing . We found evidence for a similar mechanism of action in ABHD12 -/mice in which antiviral CD8 T cells from these animals displayed increased killing capacity compared to cells from ABHD12 +/+ mice in both spleen and lung ( Fig. 6e and Supplementary Fig.","[3.0, 4.0, 4.0, 5.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.2337/db13-1600,Biology_234,"""This clearly shows that the brain can't detect hypoglycemia under most physiological conditions unless it has this peripheral input,"" Donovan said.","Insulin infusion increased plasma insulin concentrations from a mean basal value of 45.5 6 5.0 pmol/L to a hyperinsulinemic plateau of 5,194 6 510 pmol/L.","Focusing on the hindbrain, they found that if sensory input from the portal vein is eliminated, there is very little activation in the hindbrain during slow onset hypoglycemia. ""This clearly shows that the brain can't detect hypoglycemia under most physiological conditions unless it has this peripheral input,"" Donovan said. ""But neurons in the hindbrain continue to respond to fast onset hypoglycemia even in the absence of peripheral sensors.""","0.10), while CSMG animals demonstrated an 81, 78, and 82% reduction in Fos-labeled nuclei for the AP (P , 0.001), DMX (P , 0.05), and NTS (P , 0.01), respectively. Insulin infusion increased plasma insulin concentrations from a mean basal value of 45.5 6 5.0 pmol/L to a hyperinsulinemic plateau of 5,194 6 510 pmol/L. No significant differences were observed in basal (P .","[2.0, 2.0, 1.0]",Biology,train,1.6666666666666667,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1111/gcb.13526,Biology_235,They will also explore optimizing other aspects of this crop's canopy of leaves-such as the distribution and angle of leaves-to design better soybean plants that yield more without the need for more water and other resources.,"Plants with optimal LAI are predicted to use 38% and 39% less carbon in constructing leaf tissue, than for the LAI observed in the field, under current and elevated [CO 2 ], respectively (Fig.","Alternatively, plants with fewer leaves are more water efficient, and thereby may be potentially drought tolerant."" Next, the researchers will bioengineer plants or search for varieties that naturally have fewer leaves to test these preliminary findings on a larger scale. They will also explore optimizing other aspects of this crop's canopy of leaves-such as the distribution and angle of leaves-to design better soybean plants that yield more without the need for more water and other resources.","However, as LAI is lowered below the optimum value, predicted losses in NPP become significant to the detriment of seed production. Plants with optimal LAI are predicted to use 38% and 39% less carbon in constructing leaf tissue, than for the LAI observed in the field, under current and elevated [CO 2 ], respectively (Fig. In fieldgrown soybean, it is observed to be largely maintained during seed fill through continued production of leaves, the period that is most critical for final yield .","[1.0, 2.0, 1.0, 3.0, 2.0]",Biology,train,1.8,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1016/j.cmet.2015.02.003,Biology_236,They found that infected areas in patients with bacterial skin infections also showed remarkably high salt accumulation.,We found that Na + accumulated at the site of bacterial skin infections in humans and in mice.,"A clue to this mystery came when Titze and his collaborators noticed an unusually high amount of sodium in the infected skin of mice that had been bitten by cage mates. They found that infected areas in patients with bacterial skin infections also showed remarkably high salt accumulation. Moving forward, the researchers will examine how salt accumulates in the skin and triggers immune responses, and why salt accumulates in the skin of aging adults.",We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control.,"[5.0, 4.0, 4.0, 4.0]",Biology,train,4.25,news,http://www.sciencedaily.com/releases/2015/03/150303123832.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29
10.1016/j.cell.2015.07.058,Biology_237,"""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea.",We show that either E1B-55K or E4-ORF3 is sufficient to prevent MRN binding to virus genomes ( Figure 4B ).,"This means the virus is effectively ignored while the cell responds to the more massive alarm. ""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","However, global ATM signaling could play an important role in vivo in modulating the host immune response to virus infection . We show that either E1B-55K or E4-ORF3 is sufficient to prevent MRN binding to virus genomes ( Figure 4B ). However, TP/pTP is covalently attached to the 5 0 ends of adenovirus genomes .","[2.0, 2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1186/s13578-015-0003-4,Biology_238,These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.,"We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts.","LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts. These findings suggested that H2S might be a novel target for the treatment of aging cardiovascular diseases.","I/R also increased the release of cytochrome c and down-regulated the phosphorylation of PI3K, Akt and GSK-3β in the aging rat hearts. We further found that PC increased H 2 S production rate and CSE expressions, and protected young hearts from I/R-induced cardiomyocytes damage, all of which were disappeared in the aging hearts. Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts.","[3.0, 5.0, 4.0, 2.0, 4.0]",Biology,train,3.6,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1016/j.celrep.2016.08.013,Biology_239,The researchers also found that a bacterial protein called BBK32 helps to stabilize and strengthen the bonds between the bacteria and the blood vessel wall.,"Although these data showed that BBK32 stabilizes B. burgdorferi-endothelial interactions and extends the force and shear stress range at which they occur by a catch bond mechanism, many questions remain.","The researchers found that the way B. burgdorferi moves inside blood vessels can be likened to a child swinging on monkey bars: The bacteria form bonds with the blood vessel wall, and then move by transferring force from one bond to the next, but never completely detaching from the blood vessel wall. The researchers also found that a bacterial protein called BBK32 helps to stabilize and strengthen the bonds between the bacteria and the blood vessel wall. Drugs that target BBK32 might help to prevent the spread of B. burgdorferi to joints, the heart and the nervous system, although future research is needed to test this, the researchers said.","The BBK32 catch bond force regime ranged from ~2 to 19 pN and was similar to the catch bond force regimes of selectins (~5-50 pN), which are the major molecular mediators of leukocyte rolling at the PCV shear stress range . Although these data showed that BBK32 stabilizes B. burgdorferi-endothelial interactions and extends the force and shear stress range at which they occur by a catch bond mechanism, many questions remain. Thus, multiple BBK32 ligand-binding sites could potentially form or reciprocally regulate catch bond formation.","[4.0, 3.0, 4.0, 3.0]",Biology,train,3.5,news,http://www.livescience.com/55895-lyme-disease-bacteria-spread.html
10.1111/gcb.13876,Biology_240,"Furthermore, forests and land offer the most cost-effective way to store more carbon right now.","The observation that grown forests may be sinks for carbon (Luyssaert et al., 2008; suggests that those sinks may be attributable to environmental changes (e.g., CO 2 fertilization) rather than to recovery.","Furthermore, forests and land offer the most cost-effective way to store more carbon right now. The agenda focuses on the twin truths of climate change: While we are making real progress, we need to move much more ambitiously and quickly to seize the opportunities right in front of us. In 2017, the world lost 39 million acres (nearly 16 million hectares) of tropical forests -- an area equivalent in size to Bangladesh -- at a near-record rate of 40 football fields every minute for the entire year, according to Global Forest Watch.","One would expect rates of carbon accumulation in mature forests to be lower than in regrowing forests. The observation that grown forests may be sinks for carbon (Luyssaert et al., 2008; suggests that those sinks may be attributable to environmental changes (e.g., CO 2 fertilization) rather than to recovery. However, the estimate defines intact forests as having a minimum area of 500 km 2 and, thus, is not comparable with the FAO estimate of primary forest.","[3.0, 3.0, 2.0]",Biology,train,2.6666666666666665,news,http://ct.moreover.com/?a=34958843662&p=1pl&v=1&x=ADGn1_xewWPJ_1OZt5xdOA
10.1038/s41590-018-0068-4,Biology_241,These results suggest that TLR8 acts as a key switch for protective immune responses.,"Further subgroup analysis revealed that distribution of the TLR8 allele was in fact significantly different only for subjects who had previously received the live BCG vaccine against TB (P = 0.002), whereas its distribution was not significantly different for unvaccinated subjects (P = 0.754) (Fig.","Moreover, the scientists also found that patients carrying an activating TLR8 gene variant responded better to a live vaccine against tuberculosis, which resulted in improved protection against disease. These results suggest that TLR8 acts as a key switch for protective immune responses. ""These results may enable us to develop new vaccines that will combine the safety of modern subunit vaccines with the high efficacy of live vaccines.""","8a and Supplementary Table 3 ), indicative of a protective effect of TLR8-G against PTB, as has been reported 32 . Further subgroup analysis revealed that distribution of the TLR8 allele was in fact significantly different only for subjects who had previously received the live BCG vaccine against TB (P = 0.002), whereas its distribution was not significantly different for unvaccinated subjects (P = 0.754) (Fig. In this study, vaccination with BCG was associated with significant risk protection in carriers of the TLR8-G allele (odds ratio = 0.280 [95% confidence interval, 0.105-0.742]) but not in carriers of the TLR8-A allele ( Fig.","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=33723683656&p=1pl&v=1&x=R9OQAdHcxos4adubuX4cGg
10.1016/j.cell.2014.05.006,Biology_242,"This structural signature, they find, is bound by a small protein named RanGDP.","Consistent with RanGDP-binding affinity, strong RanGDP-binding NPcIkBa-AR2s (WT, I124L and I124F) were mainly observed in the nucleus, whereas weaker mutants (NPc-IkBa-AR2[124R and 124K]) were predominantly cytoplasmic ( Figure 3B ).","Lu's team shows in the study that the import signal that flags proteins for the new pathway consists of two consecutive ARs that share one feature: each has a hydrophobic amino acid (one with chemical properties that repel water) that is located 13 amino acids into the repeat. This structural signature, they find, is bound by a small protein named RanGDP. In decoding this new nuclear import signal, Lu and her team also uncover a possible molecular mechanism underlying human familial melanomas, which are often linked to mutations in a protein known as p16.","The resulting IkBa-AR2 mutants with hydrophobic AR 13 (I124I, I124L, I124F, and I124C) all bound RanGDP with high efficiency, whereas mutants with more hydrophilic residues at AR 13 , K or R, bound RanGDP with much lower efficiency ( Figure 3B ). Consistent with RanGDP-binding affinity, strong RanGDP-binding NPcIkBa-AR2s (WT, I124L and I124F) were mainly observed in the nucleus, whereas weaker mutants (NPc-IkBa-AR2[124R and 124K]) were predominantly cytoplasmic ( Figure 3B ). ANKRD49 is predominantly cytoplasmic with four ARs, and RanGDP binding is barely detectable.","[5.0, 2.0, 4.0, 1.0]",Biology,train,4.0,news,http://www.sciencedaily.com/releases/2014/05/140522123451.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/beheco/aru103,Biology_244,"The effect was not as strong at dusk, with some birds only tweeting about 10 minutes later than usual.","We cannot exclude that early or late disturbance by humans (e.g., pedestrians, joggers) might have woken up the birds earlier during the weekend or drove the blue tits to be active later at dusk.","For instance, in areas with more artificial night light emitted by street lamps, European robins (pictured above) and blackbirds can start singing up to 1.5 hours earlier than sunrise, and great tits chirp an hour earlier than normal. The effect was not as strong at dusk, with some birds only tweeting about 10 minutes later than usual. The finding, published this week in Behavioral Ecology, suggests that birds' perception of day length is rattled by artificial light, but the disruption of the natural pattern may not be entirely bad.","High noise levels during the week may reduce the efficiency of communication, and males may compensate by singing more and somewhat earlier during the weekends. We cannot exclude that early or late disturbance by humans (e.g., pedestrians, joggers) might have woken up the birds earlier during the weekend or drove the blue tits to be active later at dusk. The absence of a clear noise effect seems to contradict previous studies that documented effects of noise pollution on the timing of singing.","[2.0, 4.0, 1.0, 3.0, 1.0]",Biology,train,2.2,news,http://news.sciencemag.org/environment/2014/06/why-are-those-birds-so-early
10.1126/sciadv.1700581,Biology_245,"advertisement

Sobering findings

The team's results suggest that by the end of the century under a business-as-usual scenario, rainfall in Jordan will decrease by 30 percent, temperatures will increase by 6 degrees Celsius, and the number and duration of droughts will double.","For meteorological drought, we find that the number of years that receive annual precipitation less than −1 SD from the baseline period progressively increases from 7 of 30 years (7 years in 1981-2010 or 23% of years) in the baseline period to 28 of 30 years (94% of years) during 2071-2100.","The authors said this approach could better inform drought management by considering all vulnerabilities for people, agriculture and the environment. advertisement

Sobering findings

The team's results suggest that by the end of the century under a business-as-usual scenario, rainfall in Jordan will decrease by 30 percent, temperatures will increase by 6 degrees Celsius, and the number and duration of droughts will double. Flow from the Yarmouk River, an important source of water that flows from Syria, would decline by up to 75 percent.","Results for the ""business-as-usual"" case show a significant increase in drought occurrence and severity. For meteorological drought, we find that the number of years that receive annual precipitation less than −1 SD from the baseline period progressively increases from 7 of 30 years (7 years in 1981-2010 or 23% of years) in the baseline period to 28 of 30 years (94% of years) during 2071-2100. Similarly, although the baseline period did not experience a precipitation deficit that falls below −2 SD, 15 of the 30 years (50% of years) during 2071-2100 are likely to experience extreme precipitation deficit, falling below −2 SD (Fig.","[3.0, 3.0, 2.0, 3.0]",Biology,train,2.75,news,https://www.sciencedaily.com/releases/2017/08/170830202128.htm
10.1111/gcb.13526,Biology_247,"In field trials, they decreased leaf area (by manually cutting off new leaflets) by just 5% and still increased yields by 8%.",Inheritance of this characteristic from the wild ancestor could also lead to overproduction of leaves.,"The model predicted that a 30-40% decrease in leaf area would increase yields by 8-10%. In field trials, they decreased leaf area (by manually cutting off new leaflets) by just 5% and still increased yields by 8%. ""The experiment indicates that that our model is conservative,"" Srinivasan said.","This results in a much greater distance between leaves than in the bush form of modern cultivated soybean. Inheritance of this characteristic from the wild ancestor could also lead to overproduction of leaves. While lowering LAI makes plants more optimal to maximize seed yield, it also makes the plants less resilient against herbivory, disease losses of leaves, and competition from neighboring plants .","[3.0, 3.0, 3.0, 3.0]",Biology,train,3.0,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1016/j.cell.2018.06.045,Biology_248,"""We saw drastic changes in the babies' immune system between each sampling, which shows that it is highly dynamic early in life.""","Collectively, these findings highlight the reactive nature of the human immune system with implications, not only for our under-standing of newborn immune systems, but also for our understanding of human immune system variation in general and how this is shaped by environmental influences.","""We saw drastic changes in the babies' immune system between each sampling, which shows that it is highly dynamic early in life."" Only small amounts of blood, just a few drops from each baby, are needed to analyse all the white blood cells and hundreds of proteins circulating in the blood. The researchers were also able to show that the babies who had abnormal development of the gut flora during the first weeks also demonstrated a disorder of the immune system.","This model does not require inputs to be identical, as long as the number of simultaneous inputs is sufficiently large and give rise to different adaptive responses. Collectively, these findings highlight the reactive nature of the human immune system with implications, not only for our under-standing of newborn immune systems, but also for our understanding of human immune system variation in general and how this is shaped by environmental influences. We also propose that in-depth analyses during early life adaptation to environmental influences provides a unique opportunity for better understanding the molecular mechanisms of immune system adaptation to environmental influences in humans.","[4.0, 5.0, 4.0]",Biology,train,4.333333333333333,news,http://ct.moreover.com/?a=34897998946&p=1pl&v=1&x=xkojRQPNCvCSHFiL-aMHjA
10.3945/jn.113.188441,Biology_25,"In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap.","We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women.","He said that can likely be attributed to biological differences (such as sex hormones and metabolism) between the sexes, as well as obesity and metabolic syndrome components. In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap. Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies.","As shown in previous reports, a high intake of refined carbohydrates such as white rice is known to increase the risk of type 2 diabetes, therefore nullifying the possible association between the MP and hyperglycemia in our study. We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women. Our findings suggest that instant noodle consumption alone might confer a higher cardiometabolic risk independent of overall dietary patterns.","[3.0, 1.0, 1.0, 2.0, 2.0]",Biology,train,1.8,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1073/pnas.1405000111,Biology_250,"Tracing back through time and examining common ancestors of migratory and non-migratory species, they were able to conclude that there was more evidence supporting the idea that birds lived year-round in North America and began migrating further and further south, resulting in today's birds migrating thousands of miles every year.","Therefore, although multiple geographic processes were likely responsible for the colonization of the tropics by emberizoids, our analyses suggest that winter ranges often reached the tropics before breeding ranges and therefore bolstered temperate-totropical colonization.","Tracing back through time and examining common ancestors of migratory and non-migratory species, they were able to conclude that there was more evidence supporting the idea that birds lived year-round in North America and began migrating further and further south, resulting in today's birds migrating thousands of miles every year. Another result of the study suggests that many tropical species of birds are descendants of migratory ancestors that lost migration and stayed in the tropics year-round. ""This is an interesting result because species diversity in this group is much higher in the tropics.","We found that both types of events occurred at high rates (Fig. Therefore, although multiple geographic processes were likely responsible for the colonization of the tropics by emberizoids, our analyses suggest that winter ranges often reached the tropics before breeding ranges and therefore bolstered temperate-totropical colonization. Our study reconciles migratory behavior with geographic origins to untangle a complex geographic history.","[2.0, 2.0, 2.0, 4.0, 4.0]",Biology,train,2.8,news,http://www.sciencedaily.com/releases/2014/08/140804151419.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.3945/jn.113.188441,Biology_251,Dr. Shin discovered that consuming instant noodles two or more times a week was associated with cardiometabolic syndrome.,"Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men.","These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs. Dr. Shin discovered that consuming instant noodles two or more times a week was associated with cardiometabolic syndrome. Dr. Shin also observed that these results were more prevalent in women.","The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ). Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men. Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women.","[4.0, 3.0, 4.0, 4.0, 2.0]",Biology,train,3.4,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.1210/en.2015-2036,Biology_252,"""Although much more research needs to be done, research from our lab and others suggests that people at risk for breast cancer should know their vitamin D levels and take steps to correct any deficiencies,"" said Brian Feldman, MD, PhD, assistant professor of pediatrics, Department of Pediatrics, Stanford University, Stanford, California.","We show that vitamin D signaling inhibits the expression of the tumor progression gene Id1, and this pathway is abrogated in vitamin D deficiency in vivo in 2 murine models of BCa.","These results suggested that vitamin D deficiency acts in a cell autonomous manner, rather than systematically, to affect breast cancer. ""Although much more research needs to be done, research from our lab and others suggests that people at risk for breast cancer should know their vitamin D levels and take steps to correct any deficiencies,"" said Brian Feldman, MD, PhD, assistant professor of pediatrics, Department of Pediatrics, Stanford University, Stanford, California. In human breast cancer cell cultures, the mechanism by which vitamin D regulated ID1 was evolutionarily conserved.","We found that ablation of vitamin D receptor expression within BCa cells accelerates primary tumor growth and enables the development of metastases, demonstrating a tumor autonomous effect of vitamin D signaling to suppress BCa metastases. We show that vitamin D signaling inhibits the expression of the tumor progression gene Id1, and this pathway is abrogated in vitamin D deficiency in vivo in 2 murine models of BCa. These findings are relevant to humans, because we discovered that the mechanism of VDR regulation of Inhibitor of differentiation 1 (ID1) is conserved in human BCa cells, and there is a negative correlation between serum 25-hydroxyvitamin D levels and the level of ID1 in primary tumors from patients with BCa.","[4.0, 3.0, 2.0, 3.0]",Biology,train,3.0,news,http://www.oncologynurseadvisor.com/lack-of-vitamin-d-may-encourage-breast-cancer-metastasis/article/485433/
10.1126/sciadv.aat5107,Biology_253,"The BioBits kits introduce molecular and synthetic biology concepts without the need for specialized lab equipment, at a fraction of the cost of current standard experimental designs.","Our custom imagers and incubators are included in BioBits™ Bright, making reaction analysis accessible for resourcelimited classrooms.","The BioBits kits introduce molecular and synthetic biology concepts without the need for specialized lab equipment, at a fraction of the cost of current standard experimental designs. The FD-CF reactions pioneered in Collins' lab for molecular manufacturing, when combined with innovations from the lab of Michael Jewett, Ph.D. at Northwestern University, offer a solution to this problem by removing bacteria from the equation altogether. ""Challenging the students to build their own in vitro synthetic programs also allows educators to start to talk about how synthetic biologists might control biology to make important products, such as medicines or chemicals,"" explained Jessica Stark, an NSF Graduate Research Fellow in the Jewett lab at Northwestern University who is co-first author on both papers.","This is made possible by our in-house freeze-dried reactions, which are two orders of magnitude more affordable than existing commercial cell-free kits, at just ~US$0.01 per microliter of reaction volume (table S3) compared to ~US$1 per microliter (Promega L110; NEB E6800S). Our custom imagers and incubators are included in BioBits™ Bright, making reaction analysis accessible for resourcelimited classrooms. Because of the highly portable, cost-effective, and user-friendly nature of the reagents and laboratory activities, the BioBits™ Bright and Explorer kits have utility both inside and outside of a formal classroom or laboratory setting.","[3.0, 5.0, 3.0, 4.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=34696777548&p=1pl&v=1&x=pxhPjHWCPi8TfA-LxM_Vbw
10.1111/1365-2656.12871,Biology_254,Our study shows the first evidence that both viruses work in tandem to control rabbit population numbers.,The transition probabilities between the different disease states can be,"""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease. Our study shows the first evidence that both viruses work in tandem to control rabbit population numbers. It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked.""","Specifically, the categories for η DZ were (i) all individuals <90 days old, including η RHD = ""maternal antibodies"" AND/OR η MYXV = ""antibodies against MYXV"", (ii) η RHD = ""susceptible"" AND η MYXV = ""susceptible"" (individuals ≥90 days old), (iii) η RHD = ""susceptible"" AND η MYXV = ""immune"" (individuals ≥90 days old), (iv) η RHD = ""immune"" AND η MYXV = ""susceptible"" (individuals ≥90 days old) and (v) η RHD = ""immune"" AND η MYXV = ""immune"" (individuals ≥90 days old). The transition probabilities between the different disease states can be In the case of RHD, the equation was as follows:","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1016/j.cell.2018.04.034,Biology_256,This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment.,FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication.,"This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade. This suggests that a precision medicine approach to prostate cancer could help better direct immunotherapy treatment. It could also explain why some prostate cancer patients have had exceptional responses to immunotherapy while the treatment has had lackluster results overall in prostate cancer.",CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion. FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication. CDK12 mutant cases are baseline diploid and do not exhibit DNA mutational signatures linked to defects in homologous recombination.,"[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1038/s41467-018-08278-4,Biology_258,"That cartilage is a key part of joints, and shows definite progress in limb regeneration.",Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint.,"Without the proteins, the amputated toes would've healed over as normal. That cartilage is a key part of joints, and shows definite progress in limb regeneration. ""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper.","Regenerated structures include a skeletal element lined with articular cartilage and a synovial cavity, and we demonstrate that this response requires the Prg4 gene. Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint. These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound.","[4.0, 3.0, 4.0, 3.0, 3.0]",Biology,train,3.4,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1073/pnas.1414221111,Biology_259,"In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours.",S3F ).,"In this study, researchers determined that (+)-SJ733 uses a novel mechanism to kill the parasite by recruiting the immune system to eliminate malaria-infected red blood cells. In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours. After 48 hours the parasite was undetectable.","(+)-SJ733 bound to a single receptor site in P. falciparum-infected erythrocytes with equivalent affinity to its growth-inhibitory potency (k d = 50 nM; SI Appendix, Fig. S3F ). (+)-SJ733 was highly potent and efficacious against P. falciparum 3D7 0087/N9 in vivo when administered as four sequential daily oral doses in the NOD-scid IL2Rγ null mouse model (Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1186/gb-2013-14-7-r73,Biology_26,The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues.,"VlincRNAs were found in all cell lines tested, including non-cancerous cell lines and tissues (Table 1) .","""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics."" The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues. Researchers found that some of these vlincRNAs are co-opted by cancer-associated transcriptional programs.","Overall, 341 of the original 580 tumor vlincRNAs ( Table 1) overlap ENCODE vlincRNAs identified from mostly different cell lines, using a different sequencing platform (p-value 1.54 × 10 -45 ). VlincRNAs were found in all cell lines tested, including non-cancerous cell lines and tissues (Table 1) . Embryonic stem cell line H1-hEsc expressed 469 such regions, while non-cancerous normal human epidermal keratinocyte line (NHEK) and normal human umbilical vein endothelial cells (HUVEC) expressed 248 and 340 vlincRNAs, respectively (Table 1; Additional File 1,  Table S1 ).","[4.0, 5.0, 5.0, 4.0]",Biology,train,4.5,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rsif.2012.0923,Biology_260,"""We agree that phytoliths can mark enamel, [but] we don't think they're responsible for removing tissue from it,"" said study leader Peter Lucas, a dental anthropologist at Kuwait University.","However, we saw no evidence of them and they appear to be suppressed by enamel structure .","The study also found that phytoliths, hard particles produced by plants in mimicry of natural grit, might not be as bad for teeth as previously thought. ""We agree that phytoliths can mark enamel, [but] we don't think they're responsible for removing tissue from it,"" said study leader Peter Lucas, a dental anthropologist at Kuwait University. Gary Schwartz, an enamel expert at Arizona State University's Institute of Human Origins, praised the study for actually testing a common scientific assumption among anthropologists: that food items cause small-scale damage on teeth, which over time scratches and pits the enamel, wearing it down to the point where the teeth are no longer protected and begin to erode.","In this respect, enamel may resemble modern 'tough' ceramics that permit micro-cracking in a confined region under an indenter because, somewhat ironically, this inhibits the possibility of any catastrophic fracture . However, we saw no evidence of them and they appear to be suppressed by enamel structure . Instead, abrasion is likely to be the result of median cracks that turn towards the enamel surface, as is also seen in larger-scale chipping events .","[3.0, 1.0, 1.0]",Biology,train,1.6666666666666667,news,http://www.insidescience.org/content/grit-filled-foods-wore-down-early-humans-teeth/918
10.1016/j.cell.2018.04.038,Biology_263,"When telomerase is not active, each time the cells divide, the telomeres get shorter.","Comparison of the TER path in the DNA-free and DNA-bound telomerase shows that significant differences are confined to the template and 3 0 and 5 0 template-adjacent residues in the TRE and next to the TBE, respectively (Figures 4B and S3) .","Of course, there are still steps to go."" When telomerase is not active, each time the cells divide, the telomeres get shorter. TRAP plays a crucial role in adding on small pieces of DNA to the ends of chromosomes to keep them from shortening every time cells divide.","In SL4, only the STE (L4) contacts TERT ( Figure 4H ). Comparison of the TER path in the DNA-free and DNA-bound telomerase shows that significant differences are confined to the template and 3 0 and 5 0 template-adjacent residues in the TRE and next to the TBE, respectively (Figures 4B and S3) . The TRE and TBE are essential for defining the 3 0 and 5 0 template boundaries, respectively .","[3.0, 1.0, 2.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1016/j.cub.2018.06.016,Biology_264,"Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting.","Similarly, orienting metrics are highly correlated to average distance from the divider, a commonly used measure of social preference in other studies of fish social interactions ( Figure 1E ; R 2 = 0.562, p < 0.001, n = 112) .","As the project progressed, fish were exposed to non-fish objects, which failed to initiate social orienting. Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting. The presence of another fish that is not socially engaged is insufficient to trigger interaction regardless of their proximity, a finding that mirrors reciprocal social interaction in humans.","These results suggest that zebrafish interact with a conspecific by orienting their body axis and that in our assay they habituate to the social stimulus. Similarly, orienting metrics are highly correlated to average distance from the divider, a commonly used measure of social preference in other studies of fish social interactions ( Figure 1E ; R 2 = 0.562, p < 0.001, n = 112) . To determine whether this behavior is explicitly social and driven specifically by conspecifics, we performed identical experiments using an empty tank or a novel object and found no similar transient increase in orienting behavior (p = 0.367, n = 20 and p = 0.355, n = 20, respectively; Figure S1A ).","[1.0, 2.0, 3.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34657319504&p=1pl&v=1&x=IZljwk13voqosD3secxjLg
10.1016/j.cell.2018.04.034,Biology_266,"""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease.",Further study in the context of a clinical trial is warranted.,"That jumped to 7 percent for metastatic cancer, which indicates a more-aggressive form of the disease. ""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease. This could be a harbinger in early cancer,"" Chinnaiyan says.","These early clinical results support the hypothesis that metastatic prostate cancer patients who harbor biallelic CDK12 loss may have a higher likelihood of response to immunotherapy than an unselected metastatic prostate cancer population. Further study in the context of a clinical trial is warranted. Importantly, through an integrative genomic approach, we demonstrate that CDK12 mutations are mutually exclusive with other PGDs, such as SPOP mutations and ETS fusions.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1038/s41467-018-07557-4,Biology_267,"The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports.","For example, at least 19 large settlements (population > 5000) are predicted to occur in the highest hazard zone (estimate = 22), but the number could be as large as 34.","""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper. The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports. ""The potential risk to railways appears to be especially high,"" the team noted.","Considering the uncertainty embedded in the projections of ground temperature and annual thaw depth, the quantity of infrastructure potentially under risk is probably not considerably smaller (lower limit), but could be substantially larger (upper limit) than estimated ( Fig. For example, at least 19 large settlements (population > 5000) are predicted to occur in the highest hazard zone (estimate = 22), but the number could be as large as 34. This pattern results primarily from the overall reduction of human activity in the north, where the permafrost thaw potential is lower than in the warmer, southern regions 4 .","[2.0, 4.0, 3.0, 4.0]",Biology,train,3.25,news,http://ct.moreover.com/?a=37952323296&p=1pl&v=1&x=YZkcSHKHdqhjfYYiUvZ_gw
10.1016/j.cub.2013.11.012,Biology_268,"In fact, researchers found that Chinese migrant workers accustomed to using computers made broader generalizations when it comes to movement learning when compared to a group of age- and education-matched migrant workers who had never used computers before.","More importantly, participants exhibited significantly larger generalization when they were tested again after 14-day training ( Figure 3A ).","""We want to quickly learn about these so that we do not need to relearn all possible movements once we switch to a new computer. In fact, researchers found that Chinese migrant workers accustomed to using computers made broader generalizations when it comes to movement learning when compared to a group of age- and education-matched migrant workers who had never used computers before. While both users and non-users learned equally quickly how to move a cursor while their hands were hidden from view, computer-experienced individuals more readily generalized what they learned about movement of the cursor in one direction to movements made in other directions.","The overall tracking error was reduced across days ( Figure 3B ). More importantly, participants exhibited significantly larger generalization when they were tested again after 14-day training ( Figure 3A ). Two-way repeated-measures ANOVA revealed significant main effect on timing [before versus after training, F(1,9) = 13.08, p < 0.01] and significant interaction effect [F(4,36) = 9.48, p < 0.0001].","[2.0, 3.0, 3.0, 1.0, 4.0]",Biology,train,2.6,news,http://www.scienceworldreport.com/articles/11738/20131223/computers-change-way-brain-generalizes-movements.htm
10.1126/sciadv.aau1291,Biology_269,This tells the neurons to stop firing and effectively ends the seizure--at least in mice.,The FIP probe can detect pathological activity and then intervene to stop seizures by delivering inhibitory neurotransmitters directly to the seizure source.,"But for someone suffering from debilitating seizures, it can be an acceptable tradeoff. This tells the neurons to stop firing and effectively ends the seizure--at least in mice. Humans aren't likely to have access to the treatment any time soon.",The therapeutic potential of the FIP probe is tested in a rodent model of epilepsy. The FIP probe can detect pathological activity and then intervene to stop seizures by delivering inhibitory neurotransmitters directly to the seizure source. We anticipate that further tailored engineering of the FIP platform will enable additional applications in neural interfacing and the treatment of neurological disorders.,"[4.0, 3.0, 4.0, 2.0, 5.0]",Biology,train,3.6,news,http://ct.moreover.com/?a=34950349292&p=1pl&v=1&x=ffMz4n5n4XLtDMruPZnsFg
10.1038/nature12167,Biology_270,"""These receptors are very different--less than 10 percent sequence identity, and yet they have the same 7-transmembrane helical fold,"" Wang added.","However, an overlay of the SMO receptor structure with previously solved class A GPCR structures shows relatively high spatial conservation of the 7TM bundle (Fig.","The results showed the molecule is nearly identical to the classic GPCR shape, even though it bears almost no similarity in terms of genetic sequence. ""These receptors are very different--less than 10 percent sequence identity, and yet they have the same 7-transmembrane helical fold,"" Wang added. ""This is a great example of structural conservation of the 7-transmembrane fold,"" said Stevens.","Sequence similarity between the SMO receptor and class A GPCRs is very low (less than 10% sequence identity), and SMO and other class F receptors lack most of the conserved class A motifs, including D[E]R 3.50 Y in helix III, CWXP .50 in helix V and NP 7.50 XXY in helix VII (superscript numbers reflect the B&W numbering system for GPCRs 24 , brackets define an alternative residue and X denotes any residue). However, an overlay of the SMO receptor structure with previously solved class A GPCR structures shows relatively high spatial conservation of the 7TM bundle (Fig. 2a, b and Supplementary Fig.","[1.0, 3.0, 3.0, 3.0]",Biology,train,2.5,news,http://www.healthcanal.com/medical-breakthroughs/38297-scripps-research-institute-scientists-find-dissimilar-proteins-evolved-similar-7-part-shape.html
10.1016/j.cell.2018.04.034,Biology_271,"Tumors in which CDK12 was inactivated were responsive to immune checkpoint inhibitors, a type of immunotherapy treatment that has overall had limited success in prostate cancer.",Gene set enrichment analysis (GSEA) across the MSigDB revealed significantly perturbed curated gene sets ( Figure S4H ).,"It was found to be more common in metastatic prostate cancer compared to early stage tumors that had not spread. Tumors in which CDK12 was inactivated were responsive to immune checkpoint inhibitors, a type of immunotherapy treatment that has overall had limited success in prostate cancer. ""Because prostate cancer is so common, 7 percent is a significant number.","While most CDK12 mutants retained active androgen receptor (AR) signaling ( Figure S4F ) (Beltran et al., 2016) , their expression signature was distinct from the equivalent signatures for the other PGDs ( Figures 2D and S4G ). Gene set enrichment analysis (GSEA) across the MSigDB revealed significantly perturbed curated gene sets ( Figure S4H ). The most prominently altered were those related to oxidative phosphorylation (down), inflammatory response (up), hormone receptor signaling (down), and epithelial dedifferentiation (down).","[1.0, 4.0, 1.0, 3.0, 2.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=34322199988&p=1pl&v=1&x=uADO-y4eWDsh9N-tizLZ7Q
10.1016/j.molcel.2014.05.030,Biology_273,"The team hopes to use this information to develop new melanoma-preventive treatments, like additives that can be included in sunblocks to ramp up the skin's ability to deal with UV damage.","Furthermore, UV damage alone did not promote production of cAMP ( Figure S2E ), suggesting that in the skin UVassociated melanocytic cAMP increases depend on an intact MC1R signaling pathway initiated by MSH.","D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study. The team hopes to use this information to develop new melanoma-preventive treatments, like additives that can be included in sunblocks to ramp up the skin's ability to deal with UV damage. Having a problem with the MC1R pathway raises a person's lifetime risk of melanoma about four-fold.","However, forskolin enhanced clearance of both [6-4]-PP and CPD in all melanocyte cells tested regardless of MC1R status (Figures 1E and 1F) with no apparent effect on cell proliferation ( Figure S2) indicating photolesion clearance was not influenced by proliferative differences. Furthermore, UV damage alone did not promote production of cAMP ( Figure S2E ), suggesting that in the skin UVassociated melanocytic cAMP increases depend on an intact MC1R signaling pathway initiated by MSH. Interestingly, cAMP-enhanced repair was not limited to melanocytic lines, as a repair benefit was also observed in .","[2.0, 3.0, 3.0, 3.0]",Biology,train,2.75,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-017-01957-8,Biology_275,"Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off.",This allowed us to describe the coevolutionary process without imposing a predefined number of prey or predator types.,"In contrast, if the predator cannot adapt, the prey requires fewer resources for defence and can invest more in producing progeny"", explains Becks. Less diversity

In addition, the researchers demonstrated that predator diversity decreases when there is a dynamical trade-off. The ciliates thus develop fewer different types in order to adapt to bacterial associations and biofilms.","Such a dynamical trade-off can potentially be important for the evolutionary and the ecological dynamics of species. This allowed us to describe the coevolutionary process without imposing a predefined number of prey or predator types. Consistent with our experiment, starting from naive populations, the trade-off curve changes from an initial shape of relatively cheap defense to be more costly with coevolution.","[2.0, 2.0, 1.0, 3.0, 3.0]",Biology,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.1242/jeb.147082,Biology_277,"Perhaps rat snakes were ""just terrible"" at escaping once kingsnakes had them in their grasp, Penning reasoned.","However, blood pressures rise only slightly during constriction in boas, and less than during other behaviors such as hissing and swallowing ).","But, after hours of complex dissection, ""Lo and behold, there was no quantifiable difference,"" Penning said. Perhaps rat snakes were ""just terrible"" at escaping once kingsnakes had them in their grasp, Penning reasoned. But that experiment also failed to find a difference.","This variation and complexity indicate that we do not yet fully understand the effects of constriction, particularly on ectothermic prey. However, blood pressures rise only slightly during constriction in boas, and less than during other behaviors such as hissing and swallowing ). When kingsnakes and their prey snakes are well matched in size, our results show that the kingsnakes succeed in predation because they have superior constriction performance.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.livescience.com/58285-how-kingsnakes-eat-rat-snakes.html
10.1016/j.immuni.2019.05.007,Biology_278,"The authors noted that ""each of these antibody classes may contribute to vaccine-induced protection, and further studies and in vivo models are required to fully understand the interplay between the antibody targets and the physiological response.""","A1431 had very extensive breadth and potency not only towards all historical strains available but also towards prospective GII.4 strains that appeared after the vaccine trial, including GII.4 2012 and 2015, neither of which had circulated in the general population at the time of sample collection ( Figure 2B ).","The authors write that ""structural mapping revealed conserved epitopes, which were occluded on the virion or partially exposed, allowing for broad blockade with neutralizing activity."" These results demonstrate that infection-derived and vaccine-elicited antibodies can exhibit broad blockade and neutralization against this prevalent human pathogen. The authors noted that ""each of these antibody classes may contribute to vaccine-induced protection, and further studies and in vivo models are required to fully understand the interplay between the antibody targets and the physiological response.""","Finally, the third class of serum antibodies had a single member, A1431, which had strong blockade activity to all known historical GII.4 strains from 1987 onwards. A1431 had very extensive breadth and potency not only towards all historical strains available but also towards prospective GII.4 strains that appeared after the vaccine trial, including GII.4 2012 and 2015, neither of which had circulated in the general population at the time of sample collection ( Figure 2B ). Furthermore, A1431 potently neutralized GII.P16-GII.4 Sydney virus, a GII.4 strain that emerged 5 years post sample collection, in a human intestinal enteroid culture system ) (IC 50 5.5 ng/mL), supporting the correlation between blockade of ligand-binding potency and antibody-mediated neutralization ( Figures 2C and S1 ) (Alvarado et al., 2018; ) .","[2.0, 2.0, 1.0]",Biology,train,1.6666666666666667,news,http://ct.moreover.com/?a=39497202582&p=1pl&v=1&x=Ax4CZfiIW69ZKRWE5VBL1A
10.3945/jn.113.188441,Biology_28,"One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this.""","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity.","Some South Koreans are a little steamed--and defensive--about the study's findings. One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this."" Love for the instant noodle spans generations--it reminds the elderly of post-Korean War recovery and for the young and busy, it's quick and cheap.","Even though measurements of the glycemic index of instant noodles varied among studies , the overall glycemic load of instant noodles is high, given their high carbohydrate content ( ( . In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","[1.0, 1.0, 2.0, 2.0, 1.0]",Biology,train,1.4,news,http://www.newser.com/story/192784/new-heart-disease-culprit-ramen.html
10.1186/gb-2013-14-7-r73,Biology_281,The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers.,"Expression of vlinc_377 was restricted to K562, while ARL15 was constitutively expressed and the direction of vlinc_377 transcription was opposite from ARL15 as shown by the vlincRNA from the ENCODE/CSHL long RNAseq dataset produced with a protocol that reduced spurious second strand formation (Materials and Methods).","""Future research into the role and function of vlincRNAs holds promise for both highly targeted diagnostic tests and more precise cancer treatments. The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers. ""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics.""","However, it does not appear to be connected to ARL15, but rather represent a stand-alone independently regulated unit. Expression of vlinc_377 was restricted to K562, while ARL15 was constitutively expressed and the direction of vlinc_377 transcription was opposite from ARL15 as shown by the vlincRNA from the ENCODE/CSHL long RNAseq dataset produced with a protocol that reduced spurious second strand formation (Materials and Methods). Consistent with this, a K562-specific promoter element could be identified at the boundary of vlincRNA_377, upstream of the constitutive promoter controlling the ARL15 expression.","[2.0, 1.0, 2.0, 3.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1534/genetics.116.197285,Biology_282,"""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said.",This is because the overall number of resistance alleles that arise by NHEJ depends only weakly on c (SI section 2.4).,"They show nature still has the edge over scientists hoping to solve human problems with GM organisms. ""Basically, looking at the numbers and assuming a simple gene drive system, it's a foregone conclusion that resistance will evolve,"" Unckless said. We argue resistance could be thought of as a good thing -- if we know it's going to evolve, we can plan around it, and understand a gene drive is a temporary solution.","In contrast to de novo mutation, the cleavage rate here has very little impact on P δ (SI Fig. This is because the overall number of resistance alleles that arise by NHEJ depends only weakly on c (SI section 2.4). Lower fitness costs of the driver again decrease P δ by reducing π(t) (Fig.","[1.0, 2.0, 3.0]",Biology,train,2.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1038/s41396-017-0042-4,Biology_283,"At an altitude this high, particles are likely to travel long distances unlike particles in the lower atmosphere.","Therefore, these relationships between the size fractions of the organic aerosols and the virus and bacteria deposition rates could be also determined by the origin of air masses.","""This preponderance of long-residence viruses traveling the atmosphere likely explains why -- it's quite conceivable to have a virus swept up into the atmosphere on one continent and deposited on another,"" says virologist Curtis Suttle of the University of British Columbia. At an altitude this high, particles are likely to travel long distances unlike particles in the lower atmosphere. Not Related To Flu Epidemic

It is surprising to know that there are millions of viruses in the air.","Indeed, the effective radius (defined as the area weighted mean radius of the aerosol particles) was larger in days with Saharan dust intrusions than under marine atmospheric conditions. Therefore, these relationships between the size fractions of the organic aerosols and the virus and bacteria deposition rates could be also determined by the origin of air masses. The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere.","[3.0, 3.0, 2.0, 4.0, 4.0]",Biology,train,3.2,news,http://ct.moreover.com/?a=33241815989&p=1pl&v=1&x=QWG0hS8aFIKDkjtM81Puow
10.1186/s40168-015-0071-z,Biology_284,"advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces.","Specifically, there was a difference in the correlation of the relative abundance of various bifidobacterial species (from the bifidobacteriaterminal restriction fragment length polymorphism (Bif-TRFLP) data) with absolute (qPCR) and relative (amplicon sequencing) bifidobacterial abundance ( Figure 12 , top and bottom).","The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother. advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces. ""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said.","However, a difference was noted between secretor-fed infants and non-secretor-fed infants in which bifidobacterial species were present in high relative abundances when compared to the microbiota as a whole. Specifically, there was a difference in the correlation of the relative abundance of various bifidobacterial species (from the bifidobacteriaterminal restriction fragment length polymorphism (Bif-TRFLP) data) with absolute (qPCR) and relative (amplicon sequencing) bifidobacterial abundance ( Figure 12 , top and bottom). Both the B. longum group and B. breve are positively correlated with bifidobacterial abundance in secretorfed infants, while only B. breve holds that distinction in non-secretor-fed infants (B. bifidum is shown as correlated, but is only present in one non-secretor-fed sample for which marker gene sequencing data is present, and at a level of only 3% of total bifidobacteria).","[3.0, 4.0, 2.0, 2.0, 3.0]",Biology,train,2.8,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.171474,Biology_285,"Oxford says that the study is one of the most definitive to date, using a combination of subjective and objective data to measure teen aggression and violence in games (see also: ""No link found between violent video games and behavior,"" HSNW, 4 January 2019).","We believe the current work is the second study in the area to set the number of observations based on an a priori power analysis , and the first to specify a minimum effect size of theoretical interest.","""Despite interest in the topic by parents and policy-makers, the research has not demonstrated that there is cause for concern."" Oxford says that the study is one of the most definitive to date, using a combination of subjective and objective data to measure teen aggression and violence in games (see also: ""No link found between violent video games and behavior,"" HSNW, 4 January 2019). ""Our findings suggest that researcher biases might have influenced previous studies on this topic, and have distorted our understanding of the effects of video games,"" says co-author Dr. Netta Weinstein from Cardiff University.","Additionally, because we prespecified how we would interpret effects larger, smaller or falling in the same range as estimates from meta-analysis , the current work provides information regarding whether these links are robust enough to be considered evidence for an effect by parents, policy-makers and professional organizations. We believe the current work is the second study in the area to set the number of observations based on an a priori power analysis , and the first to specify a minimum effect size of theoretical interest. Indeed, statistical significance does not necessitate a subjective state that humans can distinguish on a personal level .","[1.0, 3.0, 1.0]",Biology,train,1.6666666666666667,news,http://ct.moreover.com/?a=38630667262&p=1pl&v=1&x=eg7bkQTzSVqLm5ru549FjQ
10.1534/genetics.116.197285,Biology_286,"The researchers conclude that, like other attempts to manipulate populations, gene drive is likely to lead to resistance alleles.","could facilitate the engineering of a successful drive by lowering resistance potential, as well as strategies that could promote resistance as a possible mechanism for controlling a drive.","""If you don't, NHEJ is going to screw things up because it creates resistance alleles,"" Unckless said. The researchers conclude that, like other attempts to manipulate populations, gene drive is likely to lead to resistance alleles. However, with this known, scientists can prepare appropriately for a dynamic gene drive system with new constructs responding to the appearance of resistance alleles.","Finally, even when assuming a comparatively small population, say N e could facilitate the engineering of a successful drive by lowering resistance potential, as well as strategies that could promote resistance as a possible mechanism for controlling a drive. This study highlights the need for careful modeling of CGD prior to the actual release of a driver construct into the wild.","[5.0, 3.0, 2.0]",Biology,train,2.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1186/s40168-015-0071-z,Biology_287,"""This work significantly advances our efforts to decipher how human milk amazingly orchestrates colonization of the infant gut by helpful bacteria, which then protects and guides intestinal development in the early stages of life.","When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ).","The researchers said that understanding the mechanism behind the observed secretor/non-secretor differences may prove critical to compensating for it in situations where the infants are vulnerable, such as by providing carefully chosen pre- or probiotics. ""This work significantly advances our efforts to decipher how human milk amazingly orchestrates colonization of the infant gut by helpful bacteria, which then protects and guides intestinal development in the early stages of life. Understanding this incredible sequence of events will provide examples for how to repair this process where it has been disrupted, such as in premature infants or colicky babies,"" Mills said.","Differences were seen between the five C-section-born infants and the 39 vaginally born infants, with C-section infants having much lower levels of bifidobacteria and Bacteroides, although the number of C-section infants was too low to draw any robust conclusions (Additional file 3: Figure S1 ). When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ). Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05).","[3.0, 4.0, 3.0]",Biology,train,3.333333333333333,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s40168-015-0071-z,Biology_288,"advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces.",Eight species of bifidobacteria were detected.,"The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother. advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces. ""The types and levels of bacteria encountered by infants in developing countries is different from the types and levels of bacteria encountered by the babies in our UC Davis cohort, and that might account for some of the differences,"" he said.","Notably, a higher abundance of non-secretor-fed infants fell into the OT area of the plot (Additional file 6: Figure S3 ). Eight species of bifidobacteria were detected. The B. longum group and B. breve were the most commonly detected.","[3.0, 2.0, 1.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/1365-2656.12871,Biology_29,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.",We did not identify any clear seasonal differences in the relative survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ) despite a variable,"""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","There was no evidence for any long-term temporal trend in changes in the survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ). We did not identify any clear seasonal differences in the relative survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ) despite a variable In contrast, survival rates of rabbits susceptible to MYXV (and immune to RHDV) were slightly higher than those of immune adults at the population-level (all odds ratios for seasonal hyperprior-level estimates 1.18-1.22, CIs ranging between 1.04 and 1.35) (Figure 2 ).","[1.0, 4.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1016/j.molcel.2014.05.030,Biology_290,"This leads to more UV light chronically getting through to the sensitive layers of the epidermis, where it can contribute to cancer.",Ser435 phosphorylation by PKA promotes ATR's physical association with XPA and directs XPA to sites of UV damage in the nucleus to accelerate repair of photodamage and protect against UVinduced mutagenesis.,"Since UV from sunlight or tanning beds is a major cause of melanoma, inherited problems in the MC1R means that the skin lacks natural protection by melanin, which acts as a biologic sunblock. This leads to more UV light chronically getting through to the sensitive layers of the epidermis, where it can contribute to cancer. Besides regulating the amount of melanin that gets made in the skin, MC1R also controls how well melanocytes can repair their DNA from UV damage.","This is the first report of a post-translational modification of ATR promoting a DNArepair specific function and the first to mechanistically link PKA to MC1R signaling and the genomic maintenance pathway responsible for clearance of UV-induced photolesions known to be causal for melanoma. Ser435 phosphorylation by PKA promotes ATR's physical association with XPA and directs XPA to sites of UV damage in the nucleus to accelerate repair of photodamage and protect against UVinduced mutagenesis. Although studies in other systems demonstrate UV-dependent ATR-XPA interactions ( , our data mechanistically link ATR and","[2.0, 2.0, 2.0, 3.0, 2.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04906-1,Biology_291,"When incorporated into a fingerprint sensor array, the result is a high-resolution device capable of accurately and reliably detecting the ridge and valley regions of a fingerprint during a touch condition.","Based on the AgNF-AgNW hybrid electrode's superb optoelectronic property and its patternability, a transparent and flexible fingerprint sensor array was demonstrated.","This network shows high optical transmission, low electrical resistance and is extremely resistant to mechanical bending. When incorporated into a fingerprint sensor array, the result is a high-resolution device capable of accurately and reliably detecting the ridge and valley regions of a fingerprint during a touch condition. The authors demonstrate the applicability of their new technology for mobile devices by integrating the fingerprint sensor arrays, pressure-sensitive transistors, and temperature sensors into smartphone displays.","10 shows that R s remained almost constant throughout this cyclic test, indicating its excellent reliability against such deformation. Based on the AgNF-AgNW hybrid electrode's superb optoelectronic property and its patternability, a transparent and flexible fingerprint sensor array was demonstrated. , which translates to 318 CPI and therefore satisfies FBI criteria.","[3.0, 2.0, 4.0, 4.0, 3.0]",Biology,train,3.2,news,http://ct.moreover.com/?a=34462398193&p=1pl&v=1&x=A28oMFBmBg6QkN0nivavQw
10.1093/molbev/msu227,Biology_292,The authors argue that the evolutionary forces at work behind the diversity of chlamydiae are the result of a unique confluence of birth and death gene evolutionary cycles.,These represent the four largest gene families (containing between 27 and 138 members) found within the phylum and include two gene families specific to Neochlamydia and two restricted to Protochlamydia.,"By combining their molecular analysis with cell-based assays, the authors demonstrated that these are thought to be secreted proteins that interfere with their hosts' defenses. The authors argue that the evolutionary forces at work behind the diversity of chlamydiae are the result of a unique confluence of birth and death gene evolutionary cycles. ""One of the most surprising findings is that a similar mode of evolution has so far only been observed in fungi, plants, and animals.""","Notably, different gene families are expanded in Neochlamydia and Protochlamydia ( fig. These represent the four largest gene families (containing between 27 and 138 members) found within the phylum and include two gene families specific to Neochlamydia and two restricted to Protochlamydia. The genomes of the Chlamydiaceae have relatively small gene family sizes.","[2.0, 2.0, 3.0, 2.0, 2.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2014/10/141014085130.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/gcb.13526,Biology_293,"""The model shows that by investing less in leaves, the plant can produce more seeds,"" Srinivasan said.",The predicted gains in yield were primarily due to decreased investment in leaves allowing predicted increase in seed production.,"If we can increase the yield of soybeans, we can solve the problems of protein demand and food production at the same time."" ""The model shows that by investing less in leaves, the plant can produce more seeds,"" Srinivasan said. The model predicted that a 30-40% decrease in leaf area would increase yields by 8-10%.","The model therefore predicts that the additional two units of LAI above the model predicted optimum would not significantly contribute to net carbon gain, as photosynthesis roughly compensated for respiratory costs (Fig. The predicted gains in yield were primarily due to decreased investment in leaves allowing predicted increase in seed production. However, as LAI is lowered below the optimum value, predicted losses in NPP become significant to the detriment of seed production.","[5.0, 5.0, 5.0, 4.0, 5.0]",Biology,train,4.8,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1016/j.cell.2014.05.006,Biology_294,"""We show that the p16 mutation most frequently associated with such cancers,"" Lu explains, ""confers the RaDAR barcode to the protein, resulting in its aberrant accumulation in the nucleus.""","However, p16(M53I) interacted with CDK4 and CDK6 as effectively as wild-type (WT) p16 in vitro and in cell lysates ( Figures 4A and 4B ).","This structural signature, they find, is bound by a small protein named RanGDP. In decoding this new nuclear import signal, Lu and her team also uncover a possible molecular mechanism underlying human familial melanomas, which are often linked to mutations in a protein known as p16. ""We show that the p16 mutation most frequently associated with such cancers,"" Lu explains, ""confers the RaDAR barcode to the protein, resulting in its aberrant accumulation in the nucleus.""","As expected, p16(R87P) exhibited a decrease in binding to CDK4 and CDK6. However, p16(M53I) interacted with CDK4 and CDK6 as effectively as wild-type (WT) p16 in vitro and in cell lysates ( Figures 4A and 4B ). p16 inhibits cell-cycle entry by preventing cyclin D/CDK4 (or CDK6) from phosphorylating RB.","[4.0, 3.0, 1.0, 3.0, 1.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140522123451.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2018.0761,Biology_295,"""Our research suggests there are hidden costs to insecticide use that may only be observed if you consider the totality of an organism's life history.","Thus, the deleterious effects observed in our treated queens were likely due to the insecticide itself, rather than being a consequence of reduced feeding in avoidance of imidacloprid.","Woodard said the data support the idea that use of neonicotinoid insecticides in the U.S. should be reconsidered. ""Our research suggests there are hidden costs to insecticide use that may only be observed if you consider the totality of an organism's life history. This is intricately linked to human well-being because bee heath is extremely important for food production, biodiversity, and the environment,"" she said.","Queens did not consume less imidacloprid-treated nectar in our feeding experiment at 5 ppb, a finding that is consistent with previous bumblebee studies that have also found equal or even greater consumption of neonicotinoid-treated versus untreated nectar (but see ). Thus, the deleterious effects observed in our treated queens were likely due to the insecticide itself, rather than being a consequence of reduced feeding in avoidance of imidacloprid. These previous findings, and our similar finding here, may have been caused in part by the negative effect of the insecticide on motor activity, which may reduce egg laying, brood feeding and other activities.","[3.0, 4.0, 2.0, 2.0]",Biology,train,2.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ea2TPwN3kfM/
10.1038/s41467-018-06108-1,Biology_296,The multiple gene copies enable the plant to assume advantageous mutations while keeping an original copy of important genes.,Drastic improvements in the genome assembly of polyploid crop species with large genomes 50-52 will facilitate genome-wide polymorphism analyses and scans for selection.,"""With these results, we have demonstrated on a molecular-genetic level that genome duplications can positively affect the adaptability of organisms,"" says plant scientist Timothy Paape. The multiple gene copies enable the plant to assume advantageous mutations while keeping an original copy of important genes. Astonishing wide spread

The usefulness of the double genome for A. kamchatica can be seen in its wider distribution -- at both low and high altitude -- compared with its parental plants.","This is consistent with the prevalence of purifying selection shown by DoS and by DFE methods. Drastic improvements in the genome assembly of polyploid crop species with large genomes 50-52 will facilitate genome-wide polymorphism analyses and scans for selection. By quantifying selection using polyploid species with different population sizes, times since polyploidization, and mating systems, general patterns of selection in polyploid genomes will emerge.","[2.0, 1.0, 3.0, 3.0, 3.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=37204299584&p=1pl&v=1&x=jPnch-e_YD0TBwdpam4EyA
10.1534/genetics.116.197285,Biology_299,So natural selection favors individuals lacking modified genes and purges a given genetic alteration within a population within a few generations.,"Briefly, in scenarios with high cleavage rate and small fitness costs, the driver will usually fix even when introduced at low 2 .","/ no comments





LAWRENCE -- Rest easy, folks. So natural selection favors individuals lacking modified genes and purges a given genetic alteration within a population within a few generations. ""By doing that they spread through a population much more quickly.""","Possible outcomes can include the fixation of the driver, loss of the driver, and both stable or unstable equilibria, depending on the cleavage rate, c, the fitness costs of the driver allele, s dd and s d0 , and the initial frequency x d (t = 0) at which the driver is introduced into the population. Briefly, in scenarios with high cleavage rate and small fitness costs, the driver will usually fix even when introduced at low 2 . 11, 2016; frequency, whereas for low c and high fitness costs the driver may not be able to invade at all.","[1.0, 1.0, 3.0, 1.0]",Biology,train,1.5,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1111/1365-2656.12871,Biology_3,"Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.",with Φ S being the average survival rate of the pool of all susceptible rabbits and the survival rate for immune rabbits set to Φ I = 1.,"""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute. ""The findings suggest a continuous benefit from both viruses and maximum impact on rabbit numbers if they act together.""","However, assuming that susceptible rabbits that do not become infected have the same survival rate as immune individuals (i.e., no prolonged disease effect) and if FoI is the proportion of individuals to become infected, infection-induced mortality rate can be approximated as follows: with Φ S being the average survival rate of the pool of all susceptible rabbits and the survival rate for immune rabbits set to Φ I = 1. Note that this approach only gives reliable output if Φ S > FoI, because only then would the proportion of susceptible rabbits not to become infected have equal survival probabilities as immune rabbits.","[2.0, 1.0, 1.0, 3.0, 2.0]",Biology,train,1.8,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1016/j.neuron.2014.05.028,Biology_30,"""It was interesting that Tac2 is highly expressed in one particular part of the amygdala, but with low or no expression in other brain areas related to the formation of fear memories.","However, this does not preclude the hypothesis that different fear paradigms might reveal a role of Tac2 in the amygdala in contextual fear conditioning.","""The Tac2 gene is robustly activated after fear learning and belongs to a pathway that can be specifically blocked with a drug,"" Ressler says. ""It was interesting that Tac2 is highly expressed in one particular part of the amygdala, but with low or no expression in other brain areas related to the formation of fear memories. Also, we found that the cells that express Tac2 are distinct from those other investigators had previously identified as being involved in fear expression.""","Interestingly, in our fear paradigm, the Tac2 gene within the amygdala is involved in auditory (CS+US paired) but not stress or contextual memories (US only). However, this does not preclude the hypothesis that different fear paradigms might reveal a role of Tac2 in the amygdala in contextual fear conditioning. Thus, we believe that enhanced Tac2 gene expression in our fear models enhanced NkB production in the amygdala, binding to Nk3R and promoting fear memory consolidation.","[2.0, 2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.3945/jn.113.188441,Biology_300,"These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs.","Dietary pattern and cardiometabolic risk factors 1249 adjustment by instant noodle intake attenuated the overall association between MP and abdominal obesity; however, the association between MP and abdominal obesity in men and the overall associations among MP and LDL cholesterol, HDL cholesterol, and hypertriglyceridemia persisted.","This association was found to be particularly strong for women. These changes could lead to increased mortality among South Koreans due to cardiovascular disease, along with increased health care costs. Dr. Shin discovered that consuming instant noodles two or more times a week was associated with cardiometabolic syndrome.","Interestingly, there was a lower prevalence of low HDL cholesterol (OR: 0.; 9% CI: 0., 0.80) and TGs $10 mg/dL (1. g/L) (OR: 0.; 9% CI: 0., 0.9) in the highest MP quintile. Dietary pattern and cardiometabolic risk factors 1249 adjustment by instant noodle intake attenuated the overall association between MP and abdominal obesity; however, the association between MP and abdominal obesity in men and the overall associations among MP and LDL cholesterol, HDL cholesterol, and hypertriglyceridemia persisted. The highest TP quintile was associated with a lower prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06) compared with the lowest quintile ( Table 4 ).","[2.0, 1.0, 2.0]",Biology,train,1.6666666666666667,news,http://www.emaxhealth.com/11402/eating-too-many-instant-noodles-could-cause-metabolic-syndrome
10.1038/s41467-019-09863-x,Biology_301,"Led by climate scientist Dmitry Yumashev of Lancaster University, the paper found that factoring in two Arctic feedback loops, regarded as key tipping points in the future of the Arctic climate, cloud inflate global temperatures and their costs by as much as 5 percent.","The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 .","If we take no further action to curb greenhouse gases, that extra cost will climb to $67 trillion by 2300, the authors said. Led by climate scientist Dmitry Yumashev of Lancaster University, the paper found that factoring in two Arctic feedback loops, regarded as key tipping points in the future of the Arctic climate, cloud inflate global temperatures and their costs by as much as 5 percent. In the scenarios modeled by Yumashev's team, the total global cost of climate change ranges from $600 to $2,100 trillion by 2300.","To put this number into context, it exceeds the estimated long-term gains from economic development in the Arctic region through transit shipping routes 52 and mineral resource extraction 53 under high emissions scenarios by around 10 times, and could also dwarf pan-Arctic damages to infrastructure from thawing permafrost 55 . The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 . Robustness of the estimates for the PCF and SAF effects.","[2.0, 2.0, 3.0, 1.0, 3.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=39063152220&p=1pl&v=1&x=rfZKa3AOnuRs3Dq6otYxhw
10.1016/j.celrep.2016.08.013,Biology_302,"Drugs that target BBK32 might help to prevent the spread of B. burgdorferi to joints, the heart and the nervous system, although future research is needed to test this, the researchers said.","B. burgdorferi extravasate extremely rapidly from PCVs (<150 ms to penetrate endothelial lining) in a process that does not require bacterial stationary adhesion and is initiated by two mechanistically distinct interaction types, tethering and dragging, which move faster and slower than 100 μm/s, respectively, along PCV surfaces .","The researchers also found that a bacterial protein called BBK32 helps to stabilize and strengthen the bonds between the bacteria and the blood vessel wall. Drugs that target BBK32 might help to prevent the spread of B. burgdorferi to joints, the heart and the nervous system, although future research is needed to test this, the researchers said. In addition, because B. burgdorferi's method of movement resembles that of leukocytes, existing drugs could be repurposed for Lyme disease, the researchers said.","Tethers and catch bonds can independently stabilize leukocyte rolling under lower shear stress conditions but act together to strengthen interactions at higher shear stresses. B. burgdorferi extravasate extremely rapidly from PCVs (<150 ms to penetrate endothelial lining) in a process that does not require bacterial stationary adhesion and is initiated by two mechanistically distinct interaction types, tethering and dragging, which move faster and slower than 100 μm/s, respectively, along PCV surfaces . Genetic bbk32 disruption does not eliminate B. burgdorferi tethering and dragging, implying that it is not the only adhesin that can mediate these interactions .","[2.0, 1.0, 3.0, 1.0]",Biology,train,1.75,news,http://www.livescience.com/55895-lyme-disease-bacteria-spread.html
10.1038/ncomms4632,Biology_303,Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power.,"Here, the assembling and actuation of nanomotors in a biosetting should be also feasible, as the same ARTICLE electric tweezers technique is used.","The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications. Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power. With all its dimensions under 1 micrometer in size, the nanomotor could fit inside a human cell and is capable of rotating for 15 continuous hours at a speed of 18,000 RPMs, the speed of a motor in a jet airplane engine.","It will also be interesting to exam the release characteristics from multiple nanomotors. Here, the assembling and actuation of nanomotors in a biosetting should be also feasible, as the same ARTICLE electric tweezers technique is used. We envision the nanomotors as a unique tool for tunable release of biochemicals to a single live cell, which is important for understanding the fundamental signal transduction on single-cell levels 5 .","[3.0, 2.0, 1.0, 2.0, 3.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Biology_304,It shows you can produce profound changes in the brain with training.,"The improvement of performance on tests such as the Rey Figure by the retired taxi drivers is also interesting in that it may indicate that the 'elderly' hippocampus can support memory improvement, in contrast with the more traditional view of age-related memory decline.","""But it turns out it really was the training process that caused the growth in the brain. It shows you can produce profound changes in the brain with training. That's a big deal.""","during acquisition and use of expertise, and then again when use of the skill ceases, serves to highlight that expertise and its behavioural consequences may be plastic and, in the case of the hippocampus at least, so are the related structural brain changes. The improvement of performance on tests such as the Rey Figure by the retired taxi drivers is also interesting in that it may indicate that the 'elderly' hippocampus can support memory improvement, in contrast with the more traditional view of age-related memory decline. First, this issue has universal relevance by informing what each of us can hope to achieve, and providing much-needed insights into the basis of individual differences, as well as having relevance in the realm of education.","[4.0, 4.0, 3.0, 4.0, 5.0]",Biology,train,4.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1038/s41589-018-0155-8,Biology_306,"""The enhanced killer-T-cell activity we saw following ABHD12 deletion in the LCMV-infected mice suggests that blocking ABHD12 may enhance T-cell responses in immune suppressive environments such as chronic viral infections and cancers,"" Teijaro says.",We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig.,"At the same time, treatments that target ABHD12, reducing its activity and stimulating the immune system, might have even broader use. ""The enhanced killer-T-cell activity we saw following ABHD12 deletion in the LCMV-infected mice suggests that blocking ABHD12 may enhance T-cell responses in immune suppressive environments such as chronic viral infections and cancers,"" Teijaro says. ""We're certainly eager to explore those possibilities,"" Cravatt says.","), which adopt a more macrophage-like cell state compared to undifferentiated THP-1 cells. We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig. 16 ) and alters lyso-PS and PS content in primary human macrophages, which showed elevations in both lyso-PS and 20:4 PS following 4 or 24 h treatment with DO264 (1 µ M), but not (S)-DO271 (1 µ M) ( Fig.","[3.0, 2.0, 2.0, 3.0, 2.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1016/j.cell.2018.04.034,Biology_312,"This could be a harbinger in early cancer,"" Chinnaiyan says.",CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ).,"""It suggests that those early stage patients who have CDK12 loss are the ones who will develop metastatic disease. This could be a harbinger in early cancer,"" Chinnaiyan says. This boosts immune-fighting T-cells, which may explain why these patients benefit from immune checkpoint blockade.","However, our data, and the observations made previously in CDK12 mutant ovarian tumors , are inconsistent with that model. CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ). Overall, the genomic phenotypes of HR and CDK12 deficiency are clearly distinct.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1073/pnas.1404354111,Biology_313,"We were able to show that progenitor cells in our model and in patients with essential thrombocythemia, had a signature of excessive thrombopoietin stimulation.","Thus, TPO signaling in megakaryocytes is dispensable for platelet production; its key role in control of platelet number is via generation and stimulation of the bipotential megakaryocyte precursors.","The findings may have implications for human disease, Dr Ng said. We were able to show that progenitor cells in our model and in patients with essential thrombocythemia, had a signature of excessive thrombopoietin stimulation. ""We think this study now provides a comprehensive model of how thrombopoietin controls platelet production, and perhaps gives some insight into the biology and mechanism behind specific myeloproliferative disorders,"" Dr Ng said.","Mpl PF4cre/PF4cre mice displayed profound megakaryocytosis and thrombocytosis with a remarkable expansion of megakaryocyte-committed and multipotential progenitor cells, the latter displaying biological responses and a gene expression signature indicative of chronic TPO overstimulation as the underlying causative mechanism, despite a normal circulating TPO level. Thus, TPO signaling in megakaryocytes is dispensable for platelet production; its key role in control of platelet number is via generation and stimulation of the bipotential megakaryocyte precursors. Nevertheless, Mpl expression on megakaryocytes and platelets is essential to prevent megakaryocytosis and myeloproliferation by restricting the amount of TPO available to stimulate the production of megakaryocytes from the progenitor cell pool.","[2.0, 2.0, 1.0, 3.0, 1.0]",Biology,train,1.8,news,http://www.healthcanal.com/medical-breakthroughs/49516-solution-to-platelet-%E2%80%98puzzle%E2%80%99-uncovers-blood-disorder-link.html
10.1038/nature12167,Biology_314,"The results showed the molecule is nearly identical to the classic GPCR shape, even though it bears almost no similarity in terms of genetic sequence.","Sequence similarity between the SMO receptor and class A GPCRs is very low (less than 10% sequence identity), and SMO and other class F receptors lack most of the conserved class A motifs, including , brackets define an alternative residue and X denotes any residue).","Different Genes, Same Structure

In the study, the TSRI team solved the high-resolution structure of SMO, which is the first non-class A GPCR structure published to date (class A GPCRs are also known as rhodopsin-like GPCRs). The results showed the molecule is nearly identical to the classic GPCR shape, even though it bears almost no similarity in terms of genetic sequence. ""These receptors are very different--less than 10 percent sequence identity, and yet they have the same 7-transmembrane helical fold,"" Wang added.","Because the difference between the two protomers is small ( Supplementary Fig. Sequence similarity between the SMO receptor and class A GPCRs is very low (less than 10% sequence identity), and SMO and other class F receptors lack most of the conserved class A motifs, including , brackets define an alternative residue and X denotes any residue). However, an overlay of the SMO receptor structure with previously solved class A","[3.0, 3.0, 4.0, 1.0]",Biology,train,2.75,news,http://www.healthcanal.com/medical-breakthroughs/38297-scripps-research-institute-scientists-find-dissimilar-proteins-evolved-similar-7-part-shape.html
10.1186/s40168-015-0071-z,Biology_315,"The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother.","As shown in Figure 1 , there is a general trend towards increasing amounts of Bacteroidales and Bifidobacteriales and decreasing amounts of Lactobacillales (mostly Streptococcus) and Enterobacteriales over time.","The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota. The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother. advertisement

The researchers determined that more infants fed by secretor mothers had high levels of bifidobacteria -- 60 percent of infants versus 37.5 percent at day 6 and 80 percent versus 50 percent at day 120 -- and that infants who had more bifidobacteria had lower amounts of milk sugars left over and higher amounts of lactate in their feces.","In general, the most common bacterial groups found in all the infants were Bifidobacteriales, Lactobacillales (mostly Streptococcus), Bacteroides, Enterobacteriaceae, and Clostridiaceae. As shown in Figure 1 , there is a general trend towards increasing amounts of Bacteroidales and Bifidobacteriales and decreasing amounts of Lactobacillales (mostly Streptococcus) and Enterobacteriales over time. Differences were seen between the five C-section-born infants and the 39 vaginally born infants, with C-section infants having much lower levels of bifidobacteria and Bacteroides, although the number of C-section infants was too low to draw any robust conclusions (Additional file 3: Figure S1 ).","[3.0, 1.0, 2.0, 3.0]",Biology,train,2.25,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/srep01456,Biology_317,"Insecticide Armor

Further investigation revealed that all of these ""overexpressed"" genes were active in the tough outer shell of resistant bedbugs, and either helped neutralize pyrethroid insecticides before they could take effect or prevented them from entering the insects' bodies in the first place.","Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection.","The team identified 14 genes that coded for proteins that were expressed at higher levels in the resistant insects, compared with the nonresistant Los Angeles population. Insecticide Armor

Further investigation revealed that all of these ""overexpressed"" genes were active in the tough outer shell of resistant bedbugs, and either helped neutralize pyrethroid insecticides before they could take effect or prevented them from entering the insects' bodies in the first place. The study also revealed that despite sometimes being separated by hundreds of miles, resistant bedbug colonies utilized many of the same genes to protect themselves against pyrethroid insecticides.","Moreover, among 21 field bed bug populations tested, 100% of populations were associated with at least two molecular mechanisms (not including LA-1 the reference population), implying the prevalent involvement of multiple mechanisms of pyrethroid resistance in the field bed bug populations. Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection. The target genes tested were successfully suppressed by RNAi (Fig.","[1.0, 2.0, 1.0]",Biology,train,1.3333333333333333,news,http://news.nationalgeographic.com/news/2013/13/130314-bedbug-insecticide-resistance-pest-science/
10.1111/gcb.13276,Biology_318,"With good tools, we can make more informed decisions and better manage coral reefs.""","These standardizations are particularly important as the third pantropical bleaching event, which is expected to affect 38% of all reefs and kill >12 000 km of coral (www.globalcoralbleaching.org), is currently unfolding.","There is value in knowing which species are more resistant and why. With good tools, we can make more informed decisions and better manage coral reefs."" ""Using very large data sets, we have teased out valuable information that will help researchers identify global trends and learn about individual corals,"" says coauthor Vadim Backman, professor of biomedical engineering.","Furthermore, the effect of the uncertainty of bleaching measurement on differential bleaching of corals identified in this study (~29%) suggests that standardization of protocols and reporting would help increase the precision of susceptibility estimates and allow a global repository of standardized bleaching surveys. These standardizations are particularly important as the third pantropical bleaching event, which is expected to affect 38% of all reefs and kill >12 000 km of coral (www.globalcoralbleaching.org), is currently unfolding. Estimates of bleaching susceptibility are fundamental to assessing the resilience potential of reef sites, which can then be used to inform management decisions .","[1.0, 3.0, 4.0, 3.0]",Biology,train,2.75,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1038/nature12167,Biology_319,"The results showed the molecule is nearly identical to the classic GPCR shape, even though it bears almost no similarity in terms of genetic sequence.","The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity.","Different Genes, Same Structure

In the study, the TSRI team solved the high-resolution structure of SMO, which is the first non-class A GPCR structure published to date (class A GPCRs are also known as rhodopsin-like GPCRs). The results showed the molecule is nearly identical to the classic GPCR shape, even though it bears almost no similarity in terms of genetic sequence. ""These receptors are very different--less than 10 percent sequence identity, and yet they have the same 7-transmembrane helical fold,"" Wang added.","In cilia, the activated SMO receptor induces the modification of GLI transcription factors into the active form, thereby inhibiting the processing of GLI transcription factors into a repressor form. The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity. Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration .","[4.0, 2.0, 5.0, 4.0, 2.0]",Biology,train,4.0,news,http://www.healthcanal.com/medical-breakthroughs/38297-scripps-research-institute-scientists-find-dissimilar-proteins-evolved-similar-7-part-shape.html
10.1038/s41467-018-05870-6,Biology_32,"""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases.""",This study demonstrates that hepatic Ago2-mediated RNA silencing regulates energy expenditure during the course of obesity and its inactivation protects from obesity-associated glucose intolerance and hepatic steatosis in mice.,"""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology. ""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases."" Novel Science

The scientists caution the research is early stage.","Upon loading of Ago proteins with mature miRNAs produced by the endoribonuclease Dicer 18 , RISC represses the expression of targeted mRNA through RNA silencing . This study demonstrates that hepatic Ago2-mediated RNA silencing regulates energy expenditure during the course of obesity and its inactivation protects from obesity-associated glucose intolerance and hepatic steatosis in mice. Importantly, we discover novel roles of Ago2 in orchestrating the expression of a subset of miRNAs, including miR-802, miR-103/107, and miR148a, and in the regulation of AMP-activated protein kinase (AMPK) activation linked to protein biosynthesis-mediated energy consumption.","[1.0, 1.0, 2.0]",Biology,train,1.3333333333333333,news,http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A
10.2337/db13-1600,Biology_320,This is the first time a brain component has been shown to be involved with these different types of hypoglycemia.,5) .,"""But it's absolutely essential in slow onset hypoglycemia."" This is the first time a brain component has been shown to be involved with these different types of hypoglycemia. ""This research could have far-reaching consequences for the way treatments are developed, particularly for treatment-induced hypoglycemia,"" Donovan said.","In both groups, arterial glucose was rapidly lowered from a mean value of 5.66 6 0.2 mmol/L to 2.44 6 0.08 mmol/L within 20 min (Fig. 5) . By design, these arterial glucose values were matched; thus there were no significant differences between control and CSMG animals at any sampling point.","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1186/s13059-018-1434-0,Biology_321,"""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes.","We observed that genes displaying a low SSB-d N /d S ratio (from now on d N /d S , unless otherwise specified) were depleted in high functional impact mutations compared to those of neutral and positively selected genes (see Fig.","""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer. ""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes. We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer.","In other words, we expect that mutations strongly altering protein function in a gene under negative selection would be removed from the host genetic pool because they will hinder tumor proliferation and thus these genes will only tolerate low or no functional impact mutations. We observed that genes displaying a low SSB-d N /d S ratio (from now on d N /d S , unless otherwise specified) were depleted in high functional impact mutations compared to those of neutral and positively selected genes (see Fig. Moreover, we found that a higher d N /d S threshold increased the mean functional impact score irrespective of the method used to calculate d N /d S (Fig.","[2.0, 3.0, 2.0, 3.0, 2.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1073/pnas.1601081113,Biology_323,"Rather than continuous forest, the results suggest that for roughly two million years before humans arrived, the center of the island was a patchwork of grasslands interspersed with woodlands and shrubs.","Along the western half of the island, below 800 m elevation and to the west of the Central Highlands, the montane forests shift to dry deciduous forest dominated by drought-adapted trees and shrubs.","""Their genomes are like historical tape recorders of environmental change,"" Yoder said. Rather than continuous forest, the results suggest that for roughly two million years before humans arrived, the center of the island was a patchwork of grasslands interspersed with woodlands and shrubs. ""Madagascar wasn't completely covered by forests when humans arrived,"" Yoder said.","At elevations above 800 m, and extending well into the island's interior, the humid forest transitions to the Central Highlands, which are dominated by moist montane forest. Along the western half of the island, below 800 m elevation and to the west of the Central Highlands, the montane forests shift to dry deciduous forest dominated by drought-adapted trees and shrubs. Thus, the present classification separating the eastern and western biomes as extreme endpoints ignores the possibility that the Central Highlands might naturally have formed a vast zone of transitional vegetation.","[2.0, 2.0, 2.0, 1.0]",Biology,train,1.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/41GB1vb0sOU/
10.1016/j.cell.2015.07.058,Biology_324,"If every incoming virus spurred a similarly strong response, points out O'Shea, our cells would be frequently paused, hampering our growth.",ATM inhibition also does not impact the cytopathic effect associated with WT virus replication (data not shown).,"The MRN response to the virus stays localized and only selectively prevents viral, but not cellular, replication. If every incoming virus spurred a similarly strong response, points out O'Shea, our cells would be frequently paused, hampering our growth. And when both threats to the genome are present, MRN will activate the massive response at the DNA break; no MRN is left to respond to the virus.","Furthermore, capsid protein expression and total virus titers are similar in WT-virusinfected cells treated with DMSO, or AZ20 (Figures S3F and S3G) . ATM inhibition also does not impact the cytopathic effect associated with WT virus replication (data not shown). We conclude that the MRN-independent activation of global ATM phosphorylation does not impact viral replication ( Figure 3I ) in cell culture.","[1.0, 1.0, 3.0, 1.0, 1.0]",Biology,train,1.4,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1093/beheco/aru103,Biology_325,"After recording them at dawn and dusk in various environments, researchers found that whereas noise has little effect on them, light pollution can change the timing of their songs.","Rain could act directly through increased noise, reducing the ability to communicate effectively, or through increased costs of singing (e.g., thermoregulation costs), or indirectly as a consequence of lower light levels (cloud coverage).","After recording them at dawn and dusk in various environments, researchers found that whereas noise has little effect on them, light pollution can change the timing of their songs. For instance, in areas with more artificial night light emitted by street lamps, European robins (pictured above) and blackbirds can start singing up to 1.5 hours earlier than sunrise, and great tits chirp an hour earlier than normal. The effect was not as strong at dusk, with some birds only tweeting about 10 minutes later than usual.","As reported previously , rain delayed onset of singing (Figure 3, lower panel) , and we also show that it made birds stop singing earlier in the evening (Figure 3, upper panel) . Rain could act directly through increased noise, reducing the ability to communicate effectively, or through increased costs of singing (e.g., thermoregulation costs), or indirectly as a consequence of lower light levels (cloud coverage). The latter does seem to play a role because on nonrainy days we found that birds initiated dawn song later when the morning was overcast.","[1.0, 3.0, 3.0, 2.0, 3.0]",Biology,train,2.4,news,http://news.sciencemag.org/environment/2014/06/why-are-those-birds-so-early
10.1016/j.cub.2013.09.038,Biology_327,"This discovery is important because cilia, or flagella, dangle from all of our cells.","Under these conditions, 70% of cnk2-1 mutant cells were flagellated after 24 hr on solid media, whereas wild-type and cnk2-1:CNK2 rescue strains were 14% and 5% flagellated, respectively ( Figure 2C ).","This discovery is important because cilia, or flagella, dangle from all of our cells. But Quarmby and Hilton have discovered that disassembly speed is also important, and that the regulatory gene CNK2 plays a key role in controlling it. advertisement

Similar to how a balance between water pressure and gravity determines the height of a fountain's stream, a balance of assembly and disassembly speed determines cilia's length.","We found that both chemicals induced flagellar resorption in both WT and cnk2-1:CNK2 rescue cells but had a greatly reduced effect on cnk2-1 mutants (Figures 2A and 2B) . Under these conditions, 70% of cnk2-1 mutant cells were flagellated after 24 hr on solid media, whereas wild-type and cnk2-1:CNK2 rescue strains were 14% and 5% flagellated, respectively ( Figure 2C ). However, cnk2-1 fa1-4 double mutants did not resorb or deflagellate in response to pH shock (data not shown).","[1.0, 4.0, 3.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2013/10/131031124920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s40168-015-0071-z,Biology_328,"Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of her infant's gut microbiota.",Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community.,"The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of her infant's gut microbiota. It also reveals clues for enriching desirable bacteria in populations at risk of intestinal diseases -- such as preemies.","The distribution of the qPCR data was bimodal, with a large group of samples with low levels of bifidobacteria (<10 7.6 /g feces, average 10 6.1 ) and a separate group with high amounts of bifidobacteria (>10 8.9 /g feces, average 10 10.3 ), with a striking lack of values falling in between the two ranges ( Figure 4 ). Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).","[2.0, 3.0, 2.0, 2.0, 4.0]",Biology,train,2.6,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-019-09863-x,Biology_329,"Dr Yumashev added: ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C.","The uncertainties in the permafrost models used in this study, robustness of our PCF and SAF emulators, and uncertainties in other key parameterisations such as the carbon cycle, sea level rise, mitigation business as usual pathway and economic impacts of rising temperatures are discussed in Methods and Supplementary Notes 1-3.","Thus, the nonlinear Arctic feedbacks make the more ambitious 1.5C target marginally more economically attractive. Dr Yumashev added: ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C. ""We hope our work will lead to further assessments of multiple nonlinear processes in the Earth's climate system, both those associated with the Arctic and beyond.""","Of the two most recent studies on the cloud feedback that were based on observational constraints, one matched closely with the ECS parameterisation from IPCC AR5 adopted in PAGE-ICE, suggesting that our climate projections are robust. The uncertainties in the permafrost models used in this study, robustness of our PCF and SAF emulators, and uncertainties in other key parameterisations such as the carbon cycle, sea level rise, mitigation business as usual pathway and economic impacts of rising temperatures are discussed in Methods and Supplementary Notes 1-3. PCF is caused by additional CO 2 and methane emissions from thawing permafrost, and SAF is mostly driven by increased solar absorption due to the decline of Arctic sea ice and land snow covers.","[2.0, 2.0, 2.0, 2.0]",Biology,train,2.0,news,https://www.sciencedaily.com/releases/2019/04/190423114027.htm
10.1038/s41467-018-08278-4,Biology_33,"The results of the study showed that the regeneration process was most advanced when BMP2 was applied first, with BMP9 added a week after - in this case it led to the growth of more complete joint structures, even with some connections to the bone.",Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint.,"""These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound,"" explain the researchers in their paper. The results of the study showed that the regeneration process was most advanced when BMP2 was applied first, with BMP9 added a week after - in this case it led to the growth of more complete joint structures, even with some connections to the bone. Humans are similar to mice in terms of the way our skeletons fit together, so this is possibly something that could be transferred over.","Regenerated structures include a skeletal element lined with articular cartilage and a synovial cavity, and we demonstrate that this response requires the Prg4 gene. Combining BMP2 and BMP9 treatments in sequence stimulates the regeneration of bone and joint. These studies provide evidence that treatment of growth factors can be used to engineer a regeneration response from a non-regenerating amputation wound.","[2.0, 4.0, 4.0, 4.0, 4.0]",Biology,train,3.6,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1038/s41589-018-0155-8,Biology_330,"For example, the enhanced immune activity in the knockout and inhibitor-treated mice hints that the signs and symptoms of PHARC may have an immunological basis.","On the other hand, both DO264-treated and ABHD12 -/mice displayed heightened immunological responses to lymphocytic choriomeningitis virus (LCMV) clone 13 infection that manifested as severe lung pathology with elevated proinflammatory chemokines.","The findings suggest several possibilities to investigate with future research. For example, the enhanced immune activity in the knockout and inhibitor-treated mice hints that the signs and symptoms of PHARC may have an immunological basis. He adds that if PHARC turns out to be caused in part by chronic brain and nerve inflammation, it might be treatable, if caught early enough, with anti-inflammatory or immune-suppressing drugs.","Unlike ABHD12 -/mice, adult mice treated with DO264 exhibited minimal perturbations in auditory function. On the other hand, both DO264-treated and ABHD12 -/mice displayed heightened immunological responses to lymphocytic choriomeningitis virus (LCMV) clone 13 infection that manifested as severe lung pathology with elevated proinflammatory chemokines. These results reveal similarities and differences in the phenotypic impact of pharmacological versus genetic blockade of ABHD12 and point to a key role for this enzyme in regulating immunostimulatory lipid pathways in vivo.","[3.0, 1.0, 3.0, 1.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1098/rsif.2012.0838,Biology_331,The easiest way to peel tape away from a surface is by pulling one corner away at the largest possible angle from the sticking surface; pulling the tape at a shallow angle makes it virtually impossible to get unstuck.,"In smooth pads, internal fibres running at an angle towards the surface of the outer layer of the pads may act in a similar way.","The researchers found that this splaying behavior is rooted in the same physical principle that applies to adhesive tape. The easiest way to peel tape away from a surface is by pulling one corner away at the largest possible angle from the sticking surface; pulling the tape at a shallow angle makes it virtually impossible to get unstuck. ""This experiment shows the maximum adhesive force a frog can take,"" says Thomas Endlein, a biologist at the University of Glasgow, UK, who led the study.","Part of the control seems to be established through the directionality of the adhesive structure itself and accordingly, the direction of the forces acting on the pad. In smooth pads, internal fibres running at an angle towards the surface of the outer layer of the pads may act in a similar way. Even without any obvious directionality of the adhesive structure itself, the angle between the detachment force vector and the surface can have a strong influence on whether the pad adheres well or detaches easily.","[4.0, 1.0, 3.0, 1.0]",Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=frogs-cling-to-and-peel-from-surfaces-just-like-adhesive-tape
10.1016/j.cell.2015.07.058,Biology_333,"""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea.","In Brief gH2AX foci discriminate ''self'' and ''nonself'' genomes and determine whether a localized anti-viral or global ATM response is appropriate, providing an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability.","This means the virus is effectively ignored while the cell responds to the more massive alarm. ""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","This provides an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability. In Brief gH2AX foci discriminate ''self'' and ''nonself'' genomes and determine whether a localized anti-viral or global ATM response is appropriate, providing an elegant mechanism to neutralize viral genomes without jeopardizing cellular viability. The MDC1 scaffolding protein binds gH2AX and recruits additional MRN, ATM, DDR kinases, and effectors into nuclear foci readily visualized by light microscopy .","[1.0, 3.0, 2.0, 3.0, 1.0]",Biology,train,2.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/s41467-018-04627-5,Biology_334,"""While many parents and teachers might worry that dyslexia is permanent, reflecting intrinsic deficits in the brain, these findings demonstrate that targeted, intensive reading programs not only lead to substantial improvements in reading skills, but also change the underlying wiring of the brain's reading circuitry,"" Yeatman said.","Alternatively, plasticity in the white matter might reflect a compensatory mechanism that supports the learning process 53 .","Yeatman believes the findings can extend to schools. Teachers have the potential to develop their students' brains, regardless of whether they have the resources to provide individualized instruction for each student in their class. ""While many parents and teachers might worry that dyslexia is permanent, reflecting intrinsic deficits in the brain, these findings demonstrate that targeted, intensive reading programs not only lead to substantial improvements in reading skills, but also change the underlying wiring of the brain's reading circuitry,"" Yeatman said.","In that case, one might predict that remediation of reading difficulties would involve a ""normalization"" of deficits in white matter structure. Alternatively, plasticity in the white matter might reflect a compensatory mechanism that supports the learning process 53 . In that case, white matter tissue properties in the remediated readers would not necessarily look more similar to those in the typical reading control subjects.","[2.0, 2.0, 3.0, 3.0, 3.0]",Biology,train,2.6,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1111/gcb.13526,Biology_335,"They attribute this boost in yield to increased photosynthesis, decreased respiration, and diversion of resources that would have been invested in more leaves than seeds.",4a) are consistent with the predicted yield results (Fig.,"They tested their prediction by removing about one third of the emerging leaves on soybeans and found an 8% increase in seed yield in replicated trials. They attribute this boost in yield to increased photosynthesis, decreased respiration, and diversion of resources that would have been invested in more leaves than seeds. ""This rate is insufficient to fulfill the needs for global food security, where we need to produce 70-100% more food by 2050 to feed an estimated 9.7 billion people,"" said project co-lead Steve Long, Gutgsell Endowed Professor of Plant Biology and Crop Sciences at the Carl R. Woese Institute for Genomic Biology at Illinois.","Hence, the numerator (NPP) in the formulation for LUE remains invariant, while the denominator (PAR absorbed) decreases, resulting in an increased LUE, as we decrease LAI from the observed peak to the predicted optimum value. 4a) are consistent with the predicted yield results (Fig. Reducing LAI also decreases crop water demand by 11% under both current and elevated [CO 2 ] (Fig.","[1.0, 2.0, 1.0, 2.0, 1.0]",Biology,train,1.4,news,http://www.seeddaily.com/reports/Soybean_plants_with_fewer_leaves_yield_more_999.html
10.1016/j.cell.2018.04.038,Biology_336,"Many mutations that scientists attributed to the TEN region in fact disrupt TEN's interaction with TRAP, the researchers report in Cell.",We suggest that dimers or multimers could result from non-physiological domain swapping of TEN in one particle to IFD-TRAP in another.,"""I remember looking at this structure when we got it and thinking we had solved a significant piece of the puzzle and were the only people who had seen this. Many mutations that scientists attributed to the TEN region in fact disrupt TEN's interaction with TRAP, the researchers report in Cell. advertisement

This is the first time researchers have seen telomerase in the process of making DNA.","Human telomerase has a longer TEN-RBD linker with low sequence complexity that has been implicated in the observed dimerization and multimerization of telomerase purified under certain conditions . We suggest that dimers or multimers could result from non-physiological domain swapping of TEN in one particle to IFD-TRAP in another. Because the human TERT-TER catalytic core and IFD-TRAP-TEN-TPP1-POT1 interactions are expected to be similar to corresponding interactions in Tetrahymena , this first complete model of a telomerase with bound DNA and sstDNA-handling proteins also provides unprecedented insight into human telomerase mechanism, mutations that affect function, and recruitment to telomeres and a framework for design of telomerase targeting therapeutics.","[2.0, 2.0, 4.0, 2.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1038/ncomms4632,Biology_337,"The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications.","The excellent demonstration of nanoentities for rotary NEMS, however, required complex fabrication procedure.","The team's nanomotor is an important step toward developing miniature machines that could one day move through the body to administer insulin for diabetics when needed, or target and treat cancer cells without harming good cells. The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications. Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power.","This is also evidenced by the restricted sizes of MEMS motors of millimetres to hundreds of micrometres . The excellent demonstration of nanoentities for rotary NEMS, however, required complex fabrication procedure. Owing to the complexity of the conjugation of inorganic nanorods to molecular motors, only a few nanorods out of hundreds had been rotated.","[1.0, 3.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.compag.2016.07.028,Biology_339,"Achieving that level of specificity might allow it to recognize and track those same components across changes in appearance and location, an important consideration for a plant that develops as quickly and dynamically as corn.","This would allow the better investigation of genetic basis of WUE, which may be controlled by different genetic factors at different stages of plant development, and upscale WUE of individual plants in the greenhouse to plant communities in the field.","I think that's the beauty of this phenotyping that wasn't really possible in the past."" Achieving that level of specificity might allow it to recognize and track those same components across changes in appearance and location, an important consideration for a plant that develops as quickly and dynamically as corn. ""That's a very important connection we need to make,"" Schnable said.","By grouping daily WUE, it is also possible to estimate WUE at particular growth stages along plant's life cycle. This would allow the better investigation of genetic basis of WUE, which may be controlled by different genetic factors at different stages of plant development, and upscale WUE of individual plants in the greenhouse to plant communities in the field. The range of LWC for all 44 destructively sampled plants (combining Stage 1 and 2) is from 68.1 to 92.3%, with a mean of 80.1% and a standard deviation of 8.5%.","[2.0, 2.0, 1.0, 3.0, 2.0]",Biology,train,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1073/pnas.1511220112,Biology_340,"This is similar to humans, who have a more pronounced scapular spine that enables them to make stone tools and throw at high speeds, according to the release.",2 E and F and Fig.,"""Our study suggests that the simplest explanation, that the ancestor looked a lot like a chimp or gorilla, is the right one, at least in the shoulder."" This is similar to humans, who have a more pronounced scapular spine that enables them to make stone tools and throw at high speeds, according to the release. Primitive in some ways, derived in other ways, and different from all of them,"" Young explained in the release.","The third axis primarily distinguishes Gorilla and Pongo from all other taxa and is associated with a scapular blade that is medio-laterally wider than accounted for by PC1 alone (Fig. 2 E and F and Fig. Both the AA and AC trees locate the basal hominoid node, reflecting the common ancestral morphotype of apes, in a region consistent with hypothesized MAA proxies (Nasalis and Lagothrix) and similar to Pongo.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.natureworldnews.com/articles/16572/20150909/ape-human-evolution-more-clues-revealed-shoulders.htm
10.1016/j.cmet.2015.02.003,Biology_341,"""Chronic accumulation of salt in the tissue thus may have become rather a problem than an advantage,"" Titze says.","LPS boosted histone H3 lysine-4 trimethylation (H3K4me3) in the Nos2 gene (Figures S1D and S1E), indicating activation of Nos2 transcription .","However, with the development of effective antibiotics and other infection treatments for infection, humans may no longer need huge amounts of salt in their system to protect them, the researchers note. ""Chronic accumulation of salt in the tissue thus may have become rather a problem than an advantage,"" Titze says. Therefore, the researchers caution, their findings should in no way be taken as a recommendation of a high salt diet as beneficial for health.","Skin Na + concentrations (mean + SEM; n = 3). LPS boosted histone H3 lysine-4 trimethylation (H3K4me3) in the Nos2 gene (Figures S1D and S1E), indicating activation of Nos2 transcription . HS further augmented H3K4me3 at distinct regions in the Nos2 gene (Figures S1D and S1E).","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.techtimes.com/articles/37351/20150304/the-healthy-side-to-sodium.htm
10.1038/s41467-018-04355-w,Biology_342,"In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes.","Significant reduction in lung metastasis was observed with PF-04136309 treatment, consistent with significant reductions in both circulating and lung TME IMs (Fig.","""The way that these immune cells promote lung cancer metastases was very unexpected. In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes. ""It's important to understand that while there is so much focus on activating parts of the immune system to attack cancer, there is also a 'Jekyll and Hyde' process going on in most tumors,"" Pecot said.","Thus, targeting IMs requires a more effective strategy. Significant reduction in lung metastasis was observed with PF-04136309 treatment, consistent with significant reductions in both circulating and lung TME IMs (Fig. In accordance with a prior study using CCR2 inhibition 13 , 1 week of treatment did not significantly affect CD206 High or CD206 Low TAM subsets (Supplementary Fig.","[3.0, 2.0, 1.0, 1.0, 1.0]",Biology,train,1.6,news,http://ct.moreover.com/?a=34143256224&p=1pl&v=1&x=_B116Taw-aRVfBzYTF8X0Q
10.1111/gcb.13526,Biology_343,"""The model shows that by investing less in leaves, the plant can produce more seeds,"" Srinivasan said.","As there were no gaps between the subplot rows and adjacent rows of the same cultivar, a larger number of guard rows were unnecessary.","If we can increase the yield of soybeans, we can solve the problems of protein demand and food production at the same time."" ""The model shows that by investing less in leaves, the plant can produce more seeds,"" Srinivasan said. The model predicted that a 30-40% decrease in leaf area would increase yields by 8-10%.","All leaves had senesced in all the subplots by September 17. As there were no gaps between the subplot rows and adjacent rows of the same cultivar, a larger number of guard rows were unnecessary. The results of the statistical models for both the LAI and seed yield indicated that the block effect was not significant; however, the statistical conclusions were the same with and without including the block effect.","[1.0, 3.0, 1.0]",Biology,train,1.6666666666666667,news,http://healthmedicinet.com/news/soybean-plants-with-fewer-leaves-yield-more/
10.1073/pnas.1404354111,Biology_344,"We were able to show that progenitor cells in our model and in patients with essential thrombocythemia, had a signature of excessive thrombopoietin stimulation.","This analysis revealed that genes associated with TPO overstimulation in TPO Tg LSKs were strongly correlated with up-regulated genes in Mpl PF4cre/PF4cre LSKs, whereas the gene signature associated with TPO starvation in Mpl −/− LSKs was associated with down-regulated genes in Mpl PF4cre/PF4cre LSKs (Fig.","The findings may have implications for human disease, Dr Ng said. We were able to show that progenitor cells in our model and in patients with essential thrombocythemia, had a signature of excessive thrombopoietin stimulation. ""We think this study now provides a comprehensive model of how thrombopoietin controls platelet production, and perhaps gives some insight into the biology and mechanism behind specific myeloproliferative disorders,"" Dr Ng said.","which are expanded significantly in number, clear circulating TPO to levels observed in Mpl-replete mice, even in the absence of clearance by megakaryocytes and platelets. This analysis revealed that genes associated with TPO overstimulation in TPO Tg LSKs were strongly correlated with up-regulated genes in Mpl PF4cre/PF4cre LSKs, whereas the gene signature associated with TPO starvation in Mpl −/− LSKs was associated with down-regulated genes in Mpl PF4cre/PF4cre LSKs (Fig. This data confirms at a genetic level that Mpl expressing stem and progenitor cells in Mpl PF4cre/PF4cre mice were exposed to excessive TPO stimulation, explaining the behavior of their preprogenitor blast colonies at the single-cell level and the mechanistic basis for the myeloproliferation, megakaryocytosis, and thrombocytosis obverved in Mpl PF4cre/PF4cre mice.","[1.0, 1.0, 2.0, 5.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/medical-breakthroughs/49516-solution-to-platelet-%E2%80%98puzzle%E2%80%99-uncovers-blood-disorder-link.html
10.1016/j.cell.2018.04.034,Biology_346,"""Because prostate cancer is so common, 7 percent is a significant number.","All other PGDs had signatures dominated by translocations (49%) and fewer overall duplications (11%) than deletions (18%) or inversions (22%), further supporting the uniqueness of CDK12 mutant PCa.","Tumors in which CDK12 was inactivated were responsive to immune checkpoint inhibitors, a type of immunotherapy treatment that has overall had limited success in prostate cancer. ""Because prostate cancer is so common, 7 percent is a significant number. The fact that immune checkpoint inhibitors may be effective against this sub-type of prostate cancer makes it even more significant.","For CDK12 mutant tumors, the majority of fusions (70%) were classified as duplications within a cytoband or chromosome arm. All other PGDs had signatures dominated by translocations (49%) and fewer overall duplications (11%) than deletions (18%) or inversions (22%), further supporting the uniqueness of CDK12 mutant PCa. In addition to the singleton outlier RTKs ( Figure S6C ), we found two cases of BRAF fusions (KIAA1549-BRAF and HIPK2-BRAF) generated as a result of a CDK12-FTD ( Figures S6D and S6E ).","[1.0, 1.0, 1.0, 1.0, 3.0]",Biology,train,1.4,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.14814/phy2.13617,Biology_348,"""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said.","Nonetheless, intensity and duration response curves to light in adults provide a context for our findings.","For preschoolers, this may not only lead to trouble falling asleep one night, but to chronic problems feeling sleepy at bedtime. ""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said. The study sample size was small and it used only one intensity of light, 1,000 lux, which is far greater than the intensity of a typical handheld electronic device, she notes.","Due to differences in methodology, including variable prior light history and timing of the experimental light exposure, comparisons between our findings and others examining the melatonin suppression response must be made with caution. Nonetheless, intensity and duration response curves to light in adults provide a context for our findings. The duration response curve to light shows that a 1-h light stimulus of 10,000 lux, 10 times the intensity of light used in this study, suppressed melatonin by 39 AE 19% .","[5.0, 3.0, 1.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=33480456707&p=1pl&v=1&x=hN9hUXXld--gBVhWbWCNfA
10.1038/ncomms4632,Biology_351,"""We were able to establish and control the molecule release rate by mechanical rotation, which means our nanomotor is the first of its kind for controlling the release of drugs from the surface of nanoparticles,"" Fan said.","The excellent demonstration of nanoentities for rotary NEMS, however, required complex fabrication procedure.","They found that the faster the nanomotor rotated, the faster it released the drugs. ""We were able to establish and control the molecule release rate by mechanical rotation, which means our nanomotor is the first of its kind for controlling the release of drugs from the surface of nanoparticles,"" Fan said. ""We believe it will help advance the study of drug delivery and cell-to-cell communications.""","This is also evidenced by the restricted sizes of MEMS motors of millimetres to hundreds of micrometres . The excellent demonstration of nanoentities for rotary NEMS, however, required complex fabrication procedure. Owing to the complexity of the conjugation of inorganic nanorods to molecular motors, only a few nanorods out of hundreds had been rotated.","[2.0, 3.0, 3.0, 3.0, 4.0]",Biology,train,3.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1242/jeb.147082,Biology_352,"The rest had varied postures, with loops at different positions and angles, Penning said.","Ratsnake constriction postures were much more variable than the typical kingsnake posture, with loops placed at different positions and angles on prey, loops that overlapped one another, and with the ratsnake's head inside or outside the coil (Fig.","In contrast, just about 5 percent of the 93 rat snakes formed uniform, spring-like coils. The rest had varied postures, with loops at different positions and angles, Penning said. (Image credit: David Penning/Missouri Southern State University)

These uniform coils may partly explain why the kingsnakes could squeeze prey with a force that was between 0.7 to 6 lbs.","Peak constriction pressures were 5.3-41.6 kPa for kingsnakes and 3.2-23.7 kPa for ratsnakes (Table 3) . Ratsnake constriction postures were much more variable than the typical kingsnake posture, with loops placed at different positions and angles on prey, loops that overlapped one another, and with the ratsnake's head inside or outside the coil (Fig. Of the 93 ratsnakes, only 5.4% used spring-like coils.","[3.0, 4.0, 4.0]",Biology,train,3.6666666666666665,news,http://www.livescience.com/58285-how-kingsnakes-eat-rat-snakes.html
10.1002/emmm.201302567,Biology_355,"""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body.","Patients with severe SMA show symptoms shortly after birth, suggesting a potential developmental component of SMA pathogenesis.","""Our efforts to model the adult form of SMA were successful,"" says Kentaro Sahashi, M.D., Ph.D., a postdoctoral researcher and neurologist who is first author of the team's new paper. ""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body. We noted, importantly, marked liver and heart pathologies that were related to SMA's progression in adults.""","Compared with early-onset SMA, adult-onset SMA may have distinct pathology, as well as therapeutic responses and requirements, perhaps reflecting key differences between development and post-development. Patients with severe SMA show symptoms shortly after birth, suggesting a potential developmental component of SMA pathogenesis. ASO injection into the CNS of adult SMN2-transgenic mice mimicked adult-onset SMA, with a characteristic late-onset motor phenotype.","[4.0, 2.0, 2.0, 4.0, 3.0]",Biology,train,3.0,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1404354111,Biology_357,"""We think this study now provides a comprehensive model of how thrombopoietin controls platelet production, and perhaps gives some insight into the biology and mechanism behind specific myeloproliferative disorders,"" Dr Ng said.","However, the relationship between circulating TPO concentration and peripheral platelet counts is not always conserved in pathological states of thrombocytosis and thrombocytopenia , suggesting that a simple relationship among megakaryocyte and platelet Mpl mass, circulating TPO concentration, and the degree of stimulation of megakaryopoiesis may not always hold.","We were able to show that progenitor cells in our model and in patients with essential thrombocythemia, had a signature of excessive thrombopoietin stimulation. ""We think this study now provides a comprehensive model of how thrombopoietin controls platelet production, and perhaps gives some insight into the biology and mechanism behind specific myeloproliferative disorders,"" Dr Ng said. Download media release as a pdf.","The reciprocal relationship between platelet number and circulating TPO level is clearly evident in bone marrow transplant patients , and the key role of the TPO receptor is illustrated by the elevated circulating TPO in Mpl −/− mice (3) and the modest elevation of platelet counts in transgenic mice expressing low levels of Mpl . However, the relationship between circulating TPO concentration and peripheral platelet counts is not always conserved in pathological states of thrombocytosis and thrombocytopenia , suggesting that a simple relationship among megakaryocyte and platelet Mpl mass, circulating TPO concentration, and the degree of stimulation of megakaryopoiesis may not always hold. Administration of TPO in vivo or stimulation of bone marrow in vitro elevates megakaryocyte numbers and increases mean DNA ploidy , and the thrombocytopenia in TPO −/− mice is accompanied by reduced megakaryocyte ploidy .","[2.0, 3.0, 3.0, 2.0]",Biology,train,2.5,news,http://www.healthcanal.com/medical-breakthroughs/49516-solution-to-platelet-%E2%80%98puzzle%E2%80%99-uncovers-blood-disorder-link.html
10.1016/j.cmet.2015.02.003,Biology_358,"""Our current study challenges this one-sided view and suggests that increasing salt accumulation at the site of infections might be an ancient strategy to ward off infections, long before antibiotics were invented.""",show that Na + accumulates in infected skin in humans and mice and creates a hypertonic microenvironment increasing NO production in macrophages to facilitate pathogen removal.,"While too much salt may not be the best for your health, dietary salt could actually have some benefits. ""Our current study challenges this one-sided view and suggests that increasing salt accumulation at the site of infections might be an ancient strategy to ward off infections, long before antibiotics were invented."" The researchers noticed that there was an unusually high amount of sodium in the infected skin of mice that had been bitten by cage mates.","We suggest that the hypertonic microenvironment could serve as a barrier to infection. show that Na + accumulates in infected skin in humans and mice and creates a hypertonic microenvironment increasing NO production in macrophages to facilitate pathogen removal. High-salt diet promotes skin Na + accumulation, which boosts macrophage activation and helps resolve bacterial infection.","[3.0, 4.0, 4.0, 2.0, 4.0]",Biology,train,3.4,news,http://www.scienceworldreport.com/articles/22963/20150304/high-salt-diet-ward-infection-invading-microbes.htm
10.1186/s12944-018-0743-3,Biology_359,"That said, it's important to design a circuit training workout based on your level of fitness and overall goals.","In conclusion, I observed how circuit training at home can improve the calcaneus QUS status, such as QUS-SI, QUS-SOS, and QUS-BUA, as well as build muscle while losing fat mass through easy sports activities among young females.","The same is true for circuit training,"" Ryan says. That said, it's important to design a circuit training workout based on your level of fitness and overall goals. Ryan explains, ""Just because split jumps may be a good exercise for an advanced person to strengthen the legs and glutes while getting their heart rate up, a more entry-level person may be better served by a basic squat or even a 1/4 squat.""","Third, studies involving both sexes may be needed to clarify the sex-based differences in the effect of such exercise on the calcaneus QUS status. In conclusion, I observed how circuit training at home can improve the calcaneus QUS status, such as QUS-SI, QUS-SOS, and QUS-BUA, as well as build muscle while losing fat mass through easy sports activities among young females. These findings suggest that circuit training can help females attain significantly greater bone mass and muscle mass and may reduce their risk of osteoporosis or cardiovascular disease in later life.","[2.0, 4.0, 2.0, 4.0, 4.0]",Biology,train,3.2,news,http://ct.moreover.com/?a=39028000354&p=1pl&v=1&x=rNZIkXnItgXmLxg4R0B21g
10.1111/1365-2656.12871,Biology_36,"Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells.",The pool of individuals susceptible to RHDV had lower survival rates compared to those that had survived a previous infection (immune individuals).,"""By explicitly modelling the complex way that diseases behave in rabbit populations we found an unexpected result. Rabbits that survive infection with MYXV virus have lower rates of survival than rabbits not yet infected,"" says Dr. Wells. ""This is important because it confirms that MYXV virus weakens animals so that they have a lower resistance when subsequently exposed to RHDV disease.","We show that the two diseases have rather different effects on rabbit survival rates. The pool of individuals susceptible to RHDV had lower survival rates compared to those that had survived a previous infection (immune individuals). In contrast, we found that individuals susceptible to both viruses had almost always higher survival rates than individuals susceptible to RHDV but immune to MYXV.","[1.0, 5.0, 1.0, 4.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1038/s41467-018-08278-4,Biology_361,"When using the combination on mice with amputated toes, over 60 percent of the stump bones formed a layer of cartilage within three days.",Chondrogenic genes are not expressed by cells of the amputation wound in BSA-treated control digits ( Fig.,"Both joints and bones are crucial if one is trying to bring back lost limbs. When using the combination on mice with amputated toes, over 60 percent of the stump bones formed a layer of cartilage within three days. Without the proteins, the amputated toes would've healed over as normal.","1l) , but not by cells of the BSA-treated digits ( Supplementary Fig. Chondrogenic genes are not expressed by cells of the amputation wound in BSA-treated control digits ( Fig. In BMP9-treated non-cavity-forming digits, we find transcripts of Col2a1, Sox9, Acan, Fmod and Ucma up-regulated at the distal end of the stump (Fig.","[2.0, 2.0, 2.0, 4.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1038/s41467-019-09863-x,Biology_363,"In an interview with the Guardian, Yumashev called his study's results ""disheartening,"" but said nations of the world have the technological capacity to confront the crisis.","We, therefore, introduced an additional abatement rate relative to RCP2.6, the same for all the major GHGs represented in PAGE-ICE, and employed Risk Optimiser to find that it is equal to 0.24% per year for the 2°C target and 4.05% per year for the 2°C target scenario.","Even if action is taken to limit warming to 1.5degC by the end of the century, the research found melting permafrost would still add $24.8 trillion to overall climate costs. In an interview with the Guardian, Yumashev called his study's results ""disheartening,"" but said nations of the world have the technological capacity to confront the crisis. What's needed, he said, is urgency and political will.","They fall outside the range covered by the SSPW and RCPW pairs described above. We, therefore, introduced an additional abatement rate relative to RCP2.6, the same for all the major GHGs represented in PAGE-ICE, and employed Risk Optimiser to find that it is equal to 0.24% per year for the 2°C target and 4.05% per year for the 2°C target scenario. Both of these scenarios overshoot their respective targets during the second half of the 21st century and imply negative CO 2 emissions thereafter.","[1.0, 1.0, 2.0, 2.0]",Biology,train,1.5,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1038/s41467-018-04151-6,Biology_365,"""My research is giving us a new way to look at unravelling network complexity in nature.""","This analysis provided a purely algebraic condition that must be satisfied by an RPA-capable system, which has been shown to be equivalent to the requirement for integral control 23 .","Her findings, published in Nature Communications, provide a new level of understanding of cellular communication and cellular 'cognition', and have potential application in a variety of areas, including new targeted cancer therapies and drug resistance. ""My research is giving us a new way to look at unravelling network complexity in nature."" ""An example of perfect adaptation is our sense of smell,"" she said.","23 considered a special case of the IMP concerning RPA to constant exogenous inputs, in the context of providing a framework for understanding the extraordinary precision of adaptation in bacterial chemotaxis 5 . This analysis provided a purely algebraic condition that must be satisfied by an RPA-capable system, which has been shown to be equivalent to the requirement for integral control 23 . 23 , for the special case in which a particular input/output node pair is specified, thereby constructing a framework from which topological structures may be deduced relative to that input/output node pair.","[3.0, 3.0, 1.0, 1.0, 2.0]",Biology,train,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BUs3tnStd9A/
10.1126/science.aam7470,Biology_366,The authors also argued in Sciencethat the chemicals cause more damage to wildlife than they are worth.,"However, in the absence of seasonlong data, it is impossible to rule out that honey bees are also chronically exposed to sublethal levels of NNIs after planting.","""The Trump administration's approval to use toxic pesticides and genetically modified crops is an insult to our national wildlife refuges and the wildlife that rely on them,"" Rappaport Clark said. The authors also argued in Sciencethat the chemicals cause more damage to wildlife than they are worth. The rollback means that rather than continuing to impose a blanket ban on GMO crops and neonics on refuges, decisions about their use would be made on an individual basis, Fish and Wildlife Service Deputy Director Greg Sheehan said in the memo on Thursday.","The timing of honey bee deaths in Ontario, Québec, and Indiana, along with the presence of NNI residues in dead bees and hives in the spring (11, , suggested that NNI-contaminated dust generated during seeding was the main route of acute exposure ( . However, in the absence of seasonlong data, it is impossible to rule out that honey bees are also chronically exposed to sublethal levels of NNIs after planting. We detected 26 different agrochemicals that included miticides, fungicides, herbicides, NNIs, and other insecticides (tables S1 and S5).","[1.0, 3.0, 1.0, 2.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=34751959942&p=1pl&v=1&x=K3NFs_6pIgAoDjfxANQdSA
10.1093/molbev/msu227,Biology_367,The authors argue that the evolutionary forces at work behind the diversity of chlamydiae are the result of a unique confluence of birth and death gene evolutionary cycles.,"In contrast, long branch lengths in the trees and moderate overall sequence similarity indicate these proteins have diverged quite extensively (supplementary figs.","By combining their molecular analysis with cell-based assays, the authors demonstrated that these are thought to be secreted proteins that interfere with their hosts' defenses. The authors argue that the evolutionary forces at work behind the diversity of chlamydiae are the result of a unique confluence of birth and death gene evolutionary cycles. ""One of the most surprising findings is that a similar mode of evolution has so far only been observed in fungi, plants, and animals.""","S8 , Supplementary Material online), the effect does not appear to be that of homogenization. In contrast, long branch lengths in the trees and moderate overall sequence similarity indicate these proteins have diverged quite extensively (supplementary figs. S2-S6, Supplementary Material online).","[1.0, 3.0, 3.0]",Biology,train,2.333333333333333,news,http://www.sciencedaily.com/releases/2014/10/141014085130.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04627-5,Biology_368,"Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said.","It should be noted, however, that in ref.","The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said. Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said. For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said.","It is important to note that the tracts identified in this analysis, including the left hemisphere ILF, SLF, and AF, carry signals that are relevant for a number of cognitive functions 57 , not only reading . It should be noted, however, that in ref. 61 , math skills' training did not produce a significant change in the arcuate at a group level, and therefore the previous set of findings differ from ours.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1073/pnas.1620079114,Biology_37,Young adults who exhibited central adiposity gain over the course of 35 weeks had plasma erythritol levels 15-times higher at baseline than those with stable adiposity over the same period.,"However, the consistency of the erythritol results in both the central adiposity and usual glycemia comparisons lends strength to the findings, and the cluster of metabolites has biological plausibility.","Knowing how the body makes sugar alcohols, she said, opens an array of new possibilities for treatment and prevention of heart disease and Type 2 diabetes. Young adults who exhibited central adiposity gain over the course of 35 weeks had plasma erythritol levels 15-times higher at baseline than those with stable adiposity over the same period. ""Taken together,"" she said, ""these data suggest that plasma erythritol may not simply reflect elevated blood glucose, but rather may signal or lead to metabolic changes that cause weight gain and/or diabetes.","The FDR-corrected statistical tests presented herein are not as robust as tests that account for both biological and technical variation . However, the consistency of the erythritol results in both the central adiposity and usual glycemia comparisons lends strength to the findings, and the cluster of metabolites has biological plausibility. This pool-based study delivers two unique results about metabolite abundance related to a one-time measurement of glycemia and longitudinal increase in central adiposity.","[3.0, 1.0, 1.0, 1.0]",Biology,train,1.5,news,http://ct.moreover.com/?a=40332840581&p=1pl&v=1&x=pkcSn_o-Swy8HkWKnlFErg
10.1002/emmm.201302567,Biology_370,Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood.,"This ASO, when administered through neonatal ICV and/or systemic injection, efficiently ameliorates the phenotypes of several SMA mouse strains, as well as of our ASO-20-37-induced SMA-phenocopy mice ).","People who have 2-3 copies (Type II SMA) make more protein and survive longer, but can never walk. Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood. The flaw in the protein's production is understood.","These results indicate marked liver pathogenesis with consequently decreased levels of circulating IGF1, caused by hepatic SMN deficiency at the advanced-disease stages in this adult-onset SMA context. This ASO, when administered through neonatal ICV and/or systemic injection, efficiently ameliorates the phenotypes of several SMA mouse strains, as well as of our ASO-20-37-induced SMA-phenocopy mice ). At PS5, we already observed pathology in the form of impaired weight gain (p ¼ 0.0003; Fig 3B) .","[1.0, 2.0, 1.0, 3.0]",Biology,train,1.75,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.cell.2013.08.004,Biology_371,"PhysOrg notes that body-clock ""disturbances"" have also been tied to mental disorders like schizophrenia, so the findings could have even broader implications.","Period length was markedly increased in cell lines (24.8 hr with greater than 90% knockdown of Sik1 versus 22.1 hr with siNTtreated cells), and less so in vivo (23.27 hr with approximately 50% knockdown of Sik1 versus 23.04 siNT, Figure S5 ).","What we saw was the mice would actually advance their clock six hours within a day [rather than taking six days for untreated mice]."" PhysOrg notes that body-clock ""disturbances"" have also been tied to mental disorders like schizophrenia, so the findings could have even broader implications. (Click for another story related to sleep ... or lack thereof.)","To illustrate the magnitude of this effect, on day 2 the difference in phase was over 3 hr in the siNT-injected animals but was less than 1 hr in the Sik1-silenced mice ( Figure 5D ). Period length was markedly increased in cell lines (24.8 hr with greater than 90% knockdown of Sik1 versus 22.1 hr with siNTtreated cells), and less so in vivo (23.27 hr with approximately 50% knockdown of Sik1 versus 23.04 siNT, Figure S5 ). These data suggest that in addition to acute effects on gene expression, CREB may play a role in constitutive clock gene regulation.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.newser.com/story/173430/scientists-uncover-clue-to-jet-lag.html
10.1016/j.cmet.2015.02.003,Biology_372,"The mice fed the higher amounts of sodium showed stronger immune responses to the wounds, and cleared their infections faster than the mice eating less salt.",MF count was not different between the diet groups ( Figure 4B ).,"MORE Older Adults May Be OK to Eat More Salt Than Previously Thought

The discovery came about by accident, after Jens Titze, the study's senior author, noticed that mice who had been bitten by their cage mates showed higher levels of sodium in their skin than those who were wound-free. The mice fed the higher amounts of sodium showed stronger immune responses to the wounds, and cleared their infections faster than the mice eating less salt. That opens the possibility that salt may be an unrecognized contributor to the immune system, and possibly a remnant from the days before antibiotics, when mammals, including humans, needed some allies in the fight against microbes.","We found a tendency toward increased IFN-g production in HSD mice, suggesting that Leishmania-specific T cell responses may be involved in improved host defense with HSD ( Figure 4B ). MF count was not different between the diet groups ( Figure 4B ). In the end of the study, HSD animals showed increased Nfat5 mRNA levels and elevated NOS2 levels ( Figure 4C ).","[1.0, 1.0, 2.0, 1.0]",Biology,train,1.25,news,http://time.com/3730061/the-weird-benefit-of-eating-salty-food/
10.1126/science.1256773,Biology_373,"The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract.","4D, right) ; we suspect it represents a configuration of actin bundles that normally precedes furrow ingression, because it has been noted in early anaphase in several systems (5) .","""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane. The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract. advertisement

""It's not only microtubules signaling to the plasma membrane, but also microtubules signaling to the actin cortex that forms on top of the plasma membrane,"" Nguyen said.","The spacing between actin cables was 1.3 T 0.5 mm (SD; n = 140), comparable to the spacing of actincontaining contractile bands on the cortex of live frog eggs (19) . 4D, right) ; we suspect it represents a configuration of actin bundles that normally precedes furrow ingression, because it has been noted in early anaphase in several systems (5) . The furrow-selective actin bundling protein Anillin (20) colocalized with F-actin cables throughout the cortex and was enriched under AAIZs along with its binding partner septin complex (Fig.","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2014/10/141031133545.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2015.07.058,Biology_374,The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell.,"Thus, DDR foci (legend continued on next page) discriminate viral and cellular genomes and determine whether a local or global ATM response is more appropriate.","When it comes to defending against DNA viruses, however, the Salk team found something interesting: the cell's response system begins the same way (with MRN detecting either DNA or viral breaks) but never progresses to the global alarm signal in the case of the virus. The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell. The MRN response to the virus stays localized and only selectively prevents viral, but not cellular, replication.","Instead, these data indicate that viral genomes do not support the amplification of MRN-ATM activation through gH2AX DDR foci. Thus, DDR foci (legend continued on next page) discriminate viral and cellular genomes and determine whether a local or global ATM response is more appropriate. Strikingly, etoposide-induced cellular DNA damage rescues the assembly of E2A domains in DE1B-55K/DE4-ORF3-infected cells ( Figure 6B ).","[4.0, 2.0, 1.0]",Biology,train,2.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/s41467-018-04355-w,Biology_376,"In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes.","This technique revealed that 85% of the immune infiltrates stained exclusively for CD14 and CCR2, suggesting that only a small subset of CD14+/CCR2+ cells represent CD206+ TAMs (P < 10 −4 , Supplementary Fig.","""The way that these immune cells promote lung cancer metastases was very unexpected. In the new study, Pecot and his collaborators found that lung squamous carcinoma could be reclassified into just two different categories based on whether they showed a high presence of inflammatory monocytes. ""It's important to understand that while there is so much focus on activating parts of the immune system to attack cancer, there is also a 'Jekyll and Hyde' process going on in most tumors,"" Pecot said.","Consistent with mRNA expression levels, there were more dual positive cells in the Basal and Secretory subtypes in both stromal and cancer cell islet regions (Fig. This technique revealed that 85% of the immune infiltrates stained exclusively for CD14 and CCR2, suggesting that only a small subset of CD14+/CCR2+ cells represent CD206+ TAMs (P < 10 −4 , Supplementary Fig. Inflammatory monocytes correspond with poor survival and CD14.","[1.0, 1.0, 2.0]",Biology,train,1.3333333333333333,news,http://ct.moreover.com/?a=34143256224&p=1pl&v=1&x=_B116Taw-aRVfBzYTF8X0Q
10.1373/clinchem.2012.187617,Biology_377,"Yet all the shifts Scott Kelly experienced during space flight amounted to less than how much a person's microbiome might change during a course of antibiotics, or a switch from a vegan diet to a carnivorous one.",These human studies confirmed animal data suggesting that alterations in gut microbial composition are associated with obesity.,"What they found

Over the course of Scott Kelly's flight, the researchers saw changes in his gut microbiome that were not echoed in his brother's on Earth. Yet all the shifts Scott Kelly experienced during space flight amounted to less than how much a person's microbiome might change during a course of antibiotics, or a switch from a vegan diet to a carnivorous one. ""We didn't see evidence of anything that I would characterize as alarming or scary,"" such as an enrichment of disease-causing capabilities among the microbes, Vitaterna said.","After weight loss, increased amounts of Bacteroidetes (3% to 15%) and a decreased abundance of Firmicutes were observed, and these changes correlated with the percentage of weight loss and not with changes in dietary caloric content. These human studies confirmed animal data suggesting that alterations in gut microbial composition are associated with obesity. This report documented an abundance of Bifidobacterium taxa and decreased proportions of Staphylococcus aureus in children who were whose weight was within reference intervals at age 7 years than in those who were overweight or obese.","[1.0, 1.0, 3.0, 1.0, 1.0]",Biology,train,1.4,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1016/j.cell.2013.08.004,Biology_381,We also showed this effect in both peripheral tissues as well as in the clock in the brain.,"Silencing of Sik1, which is upregulated by light in the SCN, in a manner similar to Per1 ( Figure 1A ) also shows period lengthening (28.0 hr).","""Our key contribution to the project was to manipulate the SIK1 protein pharmacologically, and we revealed that such blockage of the protein's activity in combination with exposure to a natural clock resetting agent, such as light, enhanced the clock shifting response,"" Duffield said. We also showed this effect in both peripheral tissues as well as in the clock in the brain. ""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and works as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules.""","It is closely related to CsnkE, which is mutated in the Tau mutant hamster, which also shows period lengthening . Silencing of Sik1, which is upregulated by light in the SCN, in a manner similar to Per1 ( Figure 1A ) also shows period lengthening (28.0 hr). (Opn4 À/À ) show attenuated phase-shifting responses to light, which correlate with attenuated induction of Fos and Per1 in the SCN (Lupi et al., 2006; .","[1.0, 3.0, 2.0, 2.0, 1.0]",Biology,train,1.8,news,http://www.healthcanal.com/disorders-conditions/sleep/42436-researchers-identify-new-drug-target-for-treating-jet-lag-and-shift-work-disorders.html
10.1016/j.cell.2014.05.006,Biology_382,"This structural signature, they find, is bound by a small protein named RanGDP.",This may be part of the reason why the presence of a 23 AR 13Hb code for RanGDP binding enabled us to predict nuclear ARPs with high accuracy.,"Lu's team shows in the study that the import signal that flags proteins for the new pathway consists of two consecutive ARs that share one feature: each has a hydrophobic amino acid (one with chemical properties that repel water) that is located 13 amino acids into the repeat. This structural signature, they find, is bound by a small protein named RanGDP. In decoding this new nuclear import signal, Lu and her team also uncover a possible molecular mechanism underlying human familial melanomas, which are often linked to mutations in a protein known as p16.","for RanGDP binding. This may be part of the reason why the presence of a 23 AR 13Hb code for RanGDP binding enabled us to predict nuclear ARPs with high accuracy. Strikingly, detailed analysis of the 30 ARPs that contain 23 AR 13Hb revealed three functional clusters.","[4.0, 4.0, 4.0, 2.0]",Biology,train,3.5,news,http://www.sciencedaily.com/releases/2014/05/140522123451.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rstb.2008.0288,Biology_386,"""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says.","We found that the hippocampus is not required for general orientation in the city, detailed topographical knowledge of landmarks and their spatial relationships, or even for the navigation along some routes, all of which abilities were preserved.","He sees it as confirmation of the idea that cognitive exercise produces physical changes in the brain. ""The initial findings could have been explained by a correlation, that people with big hippocampi become taxi drivers,"" he says. ""But it turns out it really was the training process that caused the growth in the brain.","However, we would argue that the potential costs of expertise also warrant consideration. We found that the hippocampus is not required for general orientation in the city, detailed topographical knowledge of landmarks and their spatial relationships, or even for the navigation along some routes, all of which abilities were preserved. However, in his navigation, TT was very reliant on main artery or 'A' roads, and became lost when navigation depended instead on non-A roads (figure 4).","[2.0, 4.0, 2.0, 5.0]",Biology,train,2.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.cell.2018.04.038,Biology_388,Now we can say the problem is with a specific site within telomerase and perhaps see why the enzyme sometimes does not work properly.,"We tried to add detergent to the sample in order to reduce exposure of particles to hydrophobic environment; however, there were very few particles in holes of cryo-EM grids in the presence of detergent (0.025% IGEPAL CA-630), suggesting that telomerase holoenzyme has affinity for the hydrophobic air/ water interface.","In addition to reporting the highest level of detail ever seen of the structure of telomerase's catalytic core, shown in the animation below, the researchers report for the first time they have captured telomerase in the process of making DNA. Now we can say the problem is with a specific site within telomerase and perhaps see why the enzyme sometimes does not work properly. Of course, there are still steps to go.""","This highly purified sample showed relatively good homogeneity of particles with a uniform shape in our negative stain EM images, but very high heterogeneity in our cryo-EM images. We tried to add detergent to the sample in order to reduce exposure of particles to hydrophobic environment; however, there were very few particles in holes of cryo-EM grids in the presence of detergent (0.025% IGEPAL CA-630), suggesting that telomerase holoenzyme has affinity for the hydrophobic air/ water interface. Bacitracin can partially mimic detergent to protect exposure of telomerase particles to the air/water interface while keeping a sufficient number of particles in the holes of cryo-EM grids for data collection.","[2.0, 3.0, 3.0, 2.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1016/j.cub.2018.06.016,Biology_389,"Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting.",We further validated our finding that the vTel is important for teleost social behavior by using the GAL4/UAS system to chemo-genetically ablate different neuronal populations in the forebrain.,"As the project progressed, fish were exposed to non-fish objects, which failed to initiate social orienting. Eventually, the research team concluded that zebrafish copy each other's motions and are dependent on another socially engaged fish to begin social orienting. The presence of another fish that is not socially engaged is insufficient to trigger interaction regardless of their proximity, a finding that mirrors reciprocal social interaction in humans.","These deficits are accompanied by a disruption in the correlation between distance from the divider and social orienting ( Figure 3H ; R 2 = 0.188, p = 0.243). We further validated our finding that the vTel is important for teleost social behavior by using the GAL4/UAS system to chemo-genetically ablate different neuronal populations in the forebrain. This paradigm provides a method for temporally controlled ablation of discrete cell populations.","[3.0, 1.0, 1.0, 1.0, 2.0]",Biology,train,1.6,news,http://ct.moreover.com/?a=34657319504&p=1pl&v=1&x=IZljwk13voqosD3secxjLg
10.1016/j.cell.2013.08.004,Biology_390,The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders.,"Thus SIK1 provides negative feedback, acting to suppress the effects of light on the clock.","""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and working as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules,"" said Duffield. The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders. This drug could potentially protect against diseases and mental disorders that are brought on by disturbances of the circadian rhythms.","Knockdown of Sik1 within the SCN results in increased behavioral phase shifts and rapid re-entrainment following experimental jet lag. Thus SIK1 provides negative feedback, acting to suppress the effects of light on the clock. This pathway provides a potential target for the regulation of circadian rhythms.","[3.0, 2.0, 2.0, 5.0]",Biology,train,2.0,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.3945/jn.113.188441,Biology_393,Dr. Shin added that the study's health implications could be substantial -- particularly if it leads to people choosing healthier foods.,"As shown in previous reports, a high intake of refined carbohydrates such as white rice is known to increase the risk of type 2 diabetes, therefore nullifying the possible association between the MP and hyperglycemia in our study.","""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said. ""My hope is that this study can lay a foundation for future research about the health effects of instant noodle consumption."" Dr. Shin added that the study's health implications could be substantial -- particularly if it leads to people choosing healthier foods.","This null association between the MP and hyperglycemia might be explained by a reduced intake of carbohydrates, especially from polished white rice in the MP. As shown in previous reports, a high intake of refined carbohydrates such as white rice is known to increase the risk of type 2 diabetes, therefore nullifying the possible association between the MP and hyperglycemia in our study. We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women.","[3.0, 3.0, 2.0, 4.0]",Biology,train,3.0,news,http://www.sciencedaily.com/releases/2014/08/140812121642.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1704745114,Biology_395,The separation of these parts in the seed 'brain' also appears to be central to how it functions.',"The radicle-enriched localization of decision-making components occurred during late seed development, coincident with the temporal induction of dormancy in Arabidopsis seeds during seed maturation (SI Appendix, Supplementary Fig.","Lead author of the study, Professor George Bassel from the School of Biosciences at the University of Birmingham, says: 'Our work reveals a crucial separation between the components within a plant decision-making centre. The separation of these parts in the seed 'brain' also appears to be central to how it functions.' The mathematical theory describing the brain's function predicted that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, than to constant environments.","5Z ), the transcript is abundant in this developmental state . The radicle-enriched localization of decision-making components occurred during late seed development, coincident with the temporal induction of dormancy in Arabidopsis seeds during seed maturation (SI Appendix, Supplementary Fig. 8) .","[2.0, 4.0, 1.0, 1.0]",Biology,train,2.0,news,http://www.seeddaily.com/reports/Scientists_discover_plant_brain_controlling_seed_development_999.html
10.1016/j.cell.2015.07.058,Biology_397,The discovery could help in the development of new cancer-selective viral therapies and may help explain why aging and certain diseases seem to open the door to viral infections.,"Consistent with this, MRE11 and RAD50 protein levels are decreased in WT and DE4-ORF3-virus-infected cells that express E1B-55K (Figure 1B) .","The discovery could help in the development of new cancer-selective viral therapies and may help explain why aging and certain diseases seem to open the door to viral infections. ""Our study reveals fundamental mechanisms that distinguish DNA breaks at cellular and viral genomes to trigger different responses that protect the host,"" says Clodagh O'Shea, associate professor and senior author of the work, which was published in Cell on August 27, 2015. ""The findings may also explain why certain conditions like aging, cancer chemotherapy and inflammation make us more susceptible to viral infection.""","The subsequent assembly of newly replicated virus genomes in nuclear domains triggers global ATM signaling through an MRN-independent mechanism but does not impact viral replication. Consistent with this, MRE11 and RAD50 protein levels are decreased in WT and DE4-ORF3-virus-infected cells that express E1B-55K (Figure 1B) . Thus, even in the absence of E1B-55K-induced MRN degradation, E4-ORF3 sequesters MRE11 and NBS1 in DE1B-55K-infected cells ( Figures 1C and S1A ).","[1.0, 2.0, 1.0, 1.0, 1.0]",Biology,train,1.2,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/s41467-018-04408-0,Biology_399,"""In this way, we can eventually provide better treatment for the diseases.""","Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig.","For some reason, almost all autoimmune diseases affect women more often than men, the study, published in the journal Nature Communications, confirms. ""In this way, we can eventually provide better treatment for the diseases."" Basically, the study found that there is a critical protein called BAFF, which makes B cells (a type of lymphocyte that releases harmful antibodies) more viable.","Indeed, Tnfsf13b (Baff) mRNA in the spleen was increased in G-ARKO mice (Fig. Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig. 3e) ; thus, testosterone downregulates splenic Baff mRNA in an AR-dependent manner.","[1.0, 1.0, 2.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=34230456675&p=1pl&v=1&x=lt6z2jq1xfFKoXvXclXMKg
10.1038/s41467-018-04408-0,Biology_4,Recognition of the link between testosterone and BAFF is completely new.,"Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function.","If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent. Recognition of the link between testosterone and BAFF is completely new. The results correlate well with a previous study showing that genetic variations in BAFF can be linked to the risk of diseases such as lupus.","Hence, estradiol elevates BAFF production and accelerates autoimmune disease , whereas testosterone has the opposite effects . Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function. In conclusion, our study uncovers a previously unrecognized regulation of BAFF by testosterone.","[3.0, 2.0, 4.0, 1.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=34228585539&p=1pl&v=1&x=jeRWiJSUImhYEA135bTOfw
10.1186/s40168-015-0071-z,Biology_40,"The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors.",Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).,"The relationship between human genetics, breast milk and Bifidobacterium appears to have developed throughout mammalian evolution. The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors. The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota.","Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ). Of 35 milks from non-secretors, 20 of the matched infant stool samples were Low-Bif qPCR (57.1%).","[4.0, 4.0, 5.0, 3.0]",Biology,train,4.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-07309-4,Biology_400,"""Our research showed that VDAC2 is required for Bax to drive the response of cancer cells to conventional chemotherapy agents as well as the recently developed BH3-mimetics,"" Professor Huang said.","In the absence of VDAC2, BAX cannot drive cell death.","""We were able to follow up on this research to show that the protein, called VDAC2, was a catalyst that helped Bax associate with mitochondria and form pores in their membranes, to kill the cell,"" Associate Professor Dewson said. ""Bax is important for helping anti-cancer agents kill cells -- without Bax and its relative Bak, cancer cells cannot undergo apoptosis when treated with a range of anti-cancer therapies. ""Our research showed that VDAC2 is required for Bax to drive the response of cancer cells to conventional chemotherapy agents as well as the recently developed BH3-mimetics,"" Professor Huang said.","g VDAC2 is essential for BAX, but not BAK to target mitochondria and mediate apoptosis. In the absence of VDAC2, BAX cannot drive cell death. Although the ability of BAK to associate with mitochondria is also perturbed in VDAC2 −/− cells 31 , sufficient BAK can still target mitochondria through a VDAC2-independent mechanism to drive apoptosis.","[3.0, 4.0, 4.0, 2.0]",Biology,train,3.25,news,http://ct.moreover.com/?a=37805367219&p=1pl&v=1&x=3iEY--hRAgTuZzGYcJlaOA
10.1038/s41598-018-21058-w,Biology_401,"""We haven't seen any biological damage to skin cells or eye cells, whereas with conventional UV light we've always seen lots of biological damage,"" he says.","If these results are confirmed in other scenarios, it follows that the use of overhead low-level far-UVC light in public locations may represent a safe and efficient methodology for limiting the transmission and spread of airborne-mediated microbial diseases such as influenza and tuberculosis.","""So up until now, they're only really practical when people aren't around,"" say Brenner. ""We haven't seen any biological damage to skin cells or eye cells, whereas with conventional UV light we've always seen lots of biological damage,"" he says. Now, Brenner and his colleagues have show that UVC light can effectively kill airborne influenza.","However as discussed above, based on biophysical considerations and in contrast to the known human health safety issues associated with conventional germicidal 254-nm broad-spectrum UVC light, far-UVC light does not appear to be cytotoxic to exposed human cells and tissues in vitro or in vivo . If these results are confirmed in other scenarios, it follows that the use of overhead low-level far-UVC light in public locations may represent a safe and efficient methodology for limiting the transmission and spread of airborne-mediated microbial diseases such as influenza and tuberculosis. This results in blocking more than 95% of the UV radiation exiting the UVGI fixture, with substantial decrease in effectiveness 24 .","[1.0, 2.0, 2.0, 3.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=33262084408&p=1pl&v=1&x=IXp4Uc8cQK4KvbY3rAq2QQ
10.1073/pnas.1418979112,Biology_402,They found that species of geckos in which the adhesive system was either lost or simplified experienced elevated rates of evolution related to morphology and locomotion.,"Generally, across the tree of life, we might expect that many of the most extraordinary examples of adaptive divergence should coincide not only with the origin and retention of innovations but also with their simplification, and ultimately their loss, in association with adaptation to new situations.","""The removal of the constraints associated with adhesion allowed those gecko species to either run faster or burrow,"" said Timothy Higham, one of the researchers, in a news release. They found that species of geckos in which the adhesive system was either lost or simplified experienced elevated rates of evolution related to morphology and locomotion. In other words, the loss of sticky feet gave them greater mobility.","The association between a terrestrial lifestyle and the loss/reduction of adhesion suggests a direct link between morphology, biomechanics, and ecology. Generally, across the tree of life, we might expect that many of the most extraordinary examples of adaptive divergence should coincide not only with the origin and retention of innovations but also with their simplification, and ultimately their loss, in association with adaptation to new situations. The increase in the rate of evolutionary change in these situations suggests that the origin of an elongate body likely led not only to relaxed selection for the retention of limbs, but also to rapid adaptive selection, favoring both their loss and other associated morphological changes.","[4.0, 4.0, 3.0, 1.0, 1.0]",Biology,train,4.0,news,http://www.scienceworldreport.com/articles/20997/20150108/speedy-geckos-lose-sticky-feet-evolution-video.htm
10.1186/1742-9994-11-20,Biology_403,"In this case, the goats did not learn the task faster.","We suggest that wild and domestic goats, and possibly other ungulates, lack sophisticated forms of social learning, because individual and simple social learning mechanisms are probably more efficient for improving their survival or reproductive success .","After subjecting them to a few demonstrations most of the trained goats (9/12) successfully learned the task; ""on average, within 12 trials,"" according to the authors. In this case, the goats did not learn the task faster. This goes to show that goats ""learned through individual rather than social learning,"" researchers noted in their paper.","In Krueger and Flauger , the side at which a demonstrator was eating influenced the behaviour of observers if the demonstrator was present (i.e. We suggest that wild and domestic goats, and possibly other ungulates, lack sophisticated forms of social learning, because individual and simple social learning mechanisms are probably more efficient for improving their survival or reproductive success . Alternatively, this lack of social learning could be linked to domestication, following the relaxed dependency on conspecifics, as has been suggested for dogs .","[4.0, 4.0, 4.0, 4.0, 3.0]",Biology,train,3.8,news,http://www.csmonitor.com/Science/2014/0326/Goats-are-not-as-dumb-as-you-think-say-scientists
10.1016/j.cell.2013.09.058,Biology_404,The authors found that the diabetes drug metformin corrected the low levels of fatty acid oxidation seen in cells expressing the KSR2 mutations.,"We identified multiple rare variants in KSR2 that disrupt signaling through the Raf-MEK-ERK pathway and impair cellular fatty acid oxidation and glucose oxidation in transfected cells; effects that can be ameliorated by the commonly prescribed antidiabetic drug, metformin.","""This work adds to a growing body of evidence that genes play a major role in influencing a person's weight and may be useful for developing new ways to treat people who are heavy and develop diabetes"" adds Farooqi. The authors found that the diabetes drug metformin corrected the low levels of fatty acid oxidation seen in cells expressing the KSR2 mutations. These findings suggest that drugs like metformin may help obese patients harboring mutations in the KSR2 gene, offering exciting prospects for future pharmacological therapies and targets.","Targeted deletion of Ksr2 leads to obesity in mice, suggesting a role in energy homeostasis. We identified multiple rare variants in KSR2 that disrupt signaling through the Raf-MEK-ERK pathway and impair cellular fatty acid oxidation and glucose oxidation in transfected cells; effects that can be ameliorated by the commonly prescribed antidiabetic drug, metformin. These data establish KSR2 as an important regulator of energy intake, energy expenditure, and substrate utilization in humans.","[4.0, 5.0, 5.0, 4.0, 4.0]",Biology,train,4.4,news,http://www.sciencedaily.com/releases/2013/10/131024121446.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1420819112,Biology_406,"Body nutrient content and trophic position explained little of the variation in EN, EP, or ENP, indicating limited applicability of basic predictors of EST.","Body nutrient content and trophic position explained little of the variation in E N , E P , or E NP , indicating limited applicability of basic predictors of EST.","In all cases, including taxonomy in models substantially improved model performance, highlighting the importance of species identity for this ecosystem function. Body nutrient content and trophic position explained little of the variation in EN, EP, or ENP, indicating limited applicability of basic predictors of EST. These results highlight the overriding importance of MTE for predicting nutrient flow through organisms, but emphasize that these relationships still fall short of explaining the unique effects certain species can have on ecological processes.","In all cases, including taxonomy in models substantially improved model performance, highlighting the importance of species identity for this ecosystem function. Body nutrient content and trophic position explained little of the variation in E N , E P , or E NP , indicating limited applicability of basic predictors of EST. These results highlight the overriding importance of MTE for predicting nutrient flow through organisms, but emphasize that these relationships still fall short of explaining the unique effects certain species can have on ecological processes.","[5.0, 5.0, 5.0, 5.0, 5.0]",Biology,train,5.0,news,http://healthmedicinet.com/news/fish-type-body-size-can-help-predict-nutrient-recycling-rates/
10.1093/molbev/mst207,Biology_409,"In the dataset, which the research team under the direction of Hasselmann collected from all over the world and examined, there were, however, 53 csd alleles found in localities (in Kenya), and worldwide at least csd 87 alleles.","Because of highly ambiguous alignment, the HVR was excluded from previous studies and was not further evaluated when estimating the numbers of csd alleles in honey bee populations .","Up until now, it was assumed that there were up to 20 csd alleles. In the dataset, which the research team under the direction of Hasselmann collected from all over the world and examined, there were, however, 53 csd alleles found in localities (in Kenya), and worldwide at least csd 87 alleles. Using an evolutionary model, the scientists extrapolated 116 -- 145 csd alleles.","The combined information of amino acid differences 1) given by the inspection of the HVR and 2) existing in the HVR-flanking region (PSD including exon 8) allows the discrimination of the csd specificities from replicates encoding the same csd allele. Because of highly ambiguous alignment, the HVR was excluded from previous studies and was not further evaluated when estimating the numbers of csd alleles in honey bee populations . Our results present evidence for the existence of at least 87 csd alleles worldwide and 53 csd alleles when focused only on a restricted geographic region in Kenya.","[3.0, 2.0, 3.0, 2.0, 1.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2013/10/131031090344.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.stemcr.2018.03.019,Biology_41,X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.,"Therefore, differences in DNA methylation correlate with the X chromosome status of iPSCs.","Note: material may have been edited for length and content. For further information, please contact the cited source. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.","Specifically, iPSCs and ESCs clustered into two main groups ( Figure 1D ). Therefore, differences in DNA methylation correlate with the X chromosome status of iPSCs. These data suggested that the first principal component, which correlated with the number of active X chromosomes and captured the separation of XO/XY and XX ESCs/iPSCs as well as most variation in methylation ( Figure 1D ), corresponded to the previously described global difference in methylation between established male and female PSCs or XO and XX female PSCs (Choi et al., , 2017a .","[3.0, 2.0, 5.0, 4.0]",Biology,train,5.0,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1038/s41467-018-05402-2,Biology_410,"All-trans retinoic acid also binds and destroys the Pin1 enzyme, but in addition, it increases cells' uptake of arsenic trioxide, increasing expression of a cell membrane protein that pumps ATO into cells.",We show that ATO directly and noncovalently binds to the common cancer signaling regulator Pin1 to block multiple cancerdriving pathways and eliminate CSCs in TNBC.,"""This might significantly improve the outcomes of cancer treatment."" All-trans retinoic acid also binds and destroys the Pin1 enzyme, but in addition, it increases cells' uptake of arsenic trioxide, increasing expression of a cell membrane protein that pumps ATO into cells. Mice that lack expression of Pin1 are highly resistant to developing cancer even when their cells overexpress oncogenes or lack expression of tumor suppressors.","8) . We show that ATO directly and noncovalently binds to the common cancer signaling regulator Pin1 to block multiple cancerdriving pathways and eliminate CSCs in TNBC. These results are consistent with the previous findings that ATO shows efficacy against various hematologic malignancies and solid tumors 13 , given prevalent Pin1 overexpression in human cancers 25 .","[4.0, 3.0, 1.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34769883200&p=1pl&v=1&x=doouI4fR0QUJ9XLDoBb9yQ
10.1186/1471-2164-15-223,Biology_411,"Across all four cancer types, the new method of selecting candidate genes based on inter-tumor variation in gene expression outperformed the other methods, including the standard method of comparing mean expression in adjacent normal and tumor tissues.",Our study showed that assessment of the interindividual variation of gene expression is better at predicting cancer-associated genes than is the traditional comparison of mean gene expression in adjacent normal and tumor tissues.,"The results were consistent across 4 major cancer types: breast, colorectal, lung, and prostate cancer. Across all four cancer types, the new method of selecting candidate genes based on inter-tumor variation in gene expression outperformed the other methods, including the standard method of comparing mean expression in adjacent normal and tumor tissues. The authors cite tumor heterogeneity as the most likely reason for the success of their variance-based approach.","The average EF was slightly lower for the raw data than was it was for the processed data: 3.5 ± 0.3 vs. 3.8 ± 0.2, even though the correlation between the raw-data variance and the processed-data variance was relatively low: average, 0.52; range, 0.31 to 0.62. Our study showed that assessment of the interindividual variation of gene expression is better at predicting cancer-associated genes than is the traditional comparison of mean gene expression in adjacent normal and tumor tissues. The results were consistent for 4 major cancer types: breast, colorectal, lung, and prostate cancer.","[3.0, 5.0, 2.0, 5.0, 4.0]",Biology,train,3.8,news,http://www.sciencedaily.com/releases/2014/05/140502130235.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.neuron.2013.12.011,Biology_412,"The experiment suggested to the researchers that those nerves which normally don't respond to pain may modify themselves during prolonged injury, adding to the pain signals being sent to the brain.","Future experiments combining GCaMP imaging with pharmacological, electrophysiological, and genetic approaches will be necessary to definitively address these mechanistic possibilities.","Applying capsaicin again to different areas, the researchers discovered that more nerve branches coming from a pinched V2 nerve lit up in comparison to those coming from an uninjured one. The experiment suggested to the researchers that those nerves which normally don't respond to pain may modify themselves during prolonged injury, adding to the pain signals being sent to the brain. ""Chronic pain seems to cause serotonin to be released by the brain into the spinal cord,"" Dong stated.","Given that the most distal site of close contact between the V2 and V3 neurons is within the trigeminal ganglion, a more likely mechanism is that the somata of injured nerves, their central axons, and/or the intraganglionic domains of their peripheral axons secrete molecules, such as nerve growth factor, to sensitize neighboring uninjured nerves . Future experiments combining GCaMP imaging with pharmacological, electrophysiological, and genetic approaches will be necessary to definitively address these mechanistic possibilities. Regardless, our current study directly demonstrates a role for TRPV1 and its facilitation in primary afferent central terminals and a strategy to treat chronic pain.","[2.0, 3.0, 1.0, 1.0]",Biology,train,1.75,news,http://www.medicaldaily.com/chronic-pain-management-blocking-serotonin-may-help-end-persistent-aches-267721
10.4049/jimmunol.1400569,Biology_413,Their tests of mice and non-human primates showed that mice bred to lack C3 since birth had much less bone loss and inflammation in their gums several weeks after P. gingivalis infection compared with normal mice.,These data show that C3 is required for maximal inflammation and bone loss in P. gingivalis-induced periodontitis in mice.,"If successful, the treatment could prevent, halve, and even reverse the effects of the disease periodontitis. Their tests of mice and non-human primates showed that mice bred to lack C3 since birth had much less bone loss and inflammation in their gums several weeks after P. gingivalis infection compared with normal mice. These results persisted even after the team tied a silk string around the mice's teeth to spur microbe collection and after they observed the disease's formation on aging mice, to mimic human aging.","1B and 1C, respectively) . These data show that C3 is required for maximal inflammation and bone loss in P. gingivalis-induced periodontitis in mice. Consistent with its ability to activate C5aR independently of the canonical activation of the complement cascade, P. gingivalis retained its capacity to colonize the periodontium of C3 2/2 mice and significantly increased total microbiota counts (comparable with its effects in WT mice), as determined 7 d postinoculation (p , 0.01; Fig.","[3.0, 3.0, 4.0, 5.0]",Biology,train,3.75,news,http://www.medicaldaily.com/new-gum-disease-treatment-prevent-and-reverse-complications-involves-key-immune-system-component
10.1038/s41467-018-05187-4,Biology_414,The researchers expect that the 'SIRT7-regulated osteoblastogenesis pathway' will be a new therapeutic drug target to treat decreased osteogenesis and osteoporosis.,7 and 8) .,"The researchers expect that the 'SIRT7-regulated osteoblastogenesis pathway' will be a new therapeutic drug target to treat decreased osteogenesis and osteoporosis. A bone morphometry analysis showed that bone formation and the number of osteoblasts (bone-building cells) had been reduced. Furthermore, the researchers obtained similar results using osteoblast-specific SIRT7 deficient mice, thereby showing that (osteoblast-specific) SIRT7 is important for bone formation.","In addition, we found that SIRT7-mediated deacylation of lysine 368 facilitated depropionylation of OSX, and SIRT1 synergistically promoted depropionylation of OSX with SIRT7 ( Figs. 7 and 8) . These findings indicate that SIRT7/ SIRT1-mediated deacylation of lysine residues is required for full activation of OSX, allowing these enzymes to regulate osteoblast differentiation and bone formation.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=35005027911&p=1pl&v=1&x=MZiQ0Ol1PJOiYoVSKfwNwQ
10.1093/molbev/msv031,Biology_416,"Furthermore, these regions controlled genes that were expressed only in the prefrontal cortex of the brain, indicating that HARs may play an important role in regulating genes found to be linked to schizophrenia.","Because the HAR-associated genes are enriched in neurodevelopmental processes and results below), one may argue that the enrichment we observed when using all the human genes as background might simply indicate that both schizophrenia genes and pHAR genes are brain related.","They found that the schizophrenic loci were most strongly associated in genomic regions near the HARs that are conserved in non-human primates, and these HAR-associated schizophrenic loci are found to be under stronger evolutionary selective pressure when compared with other schizophrenic loci. Furthermore, these regions controlled genes that were expressed only in the prefrontal cortex of the brain, indicating that HARs may play an important role in regulating genes found to be linked to schizophrenia. They specifically found the greatest correlation between HAR-associated schizophrenic loci and genes controlling the expression of the neurotransmitter GABA, brain development, synaptic formations, adhesion and signaling molecules.","In addition, pHARs may not be conserved in nonprimate mammals or may be different between primates and other mammals. Because the HAR-associated genes are enriched in neurodevelopmental processes and results below), one may argue that the enrichment we observed when using all the human genes as background might simply indicate that both schizophrenia genes and pHAR genes are brain related. Both data sets yield the similar pattern of enrichment as when using all the autosomal genes as background ( fig.","[3.0, 4.0, 3.0, 2.0]",Biology,train,3.0,news,http://www.sciencedaily.com/releases/2015/02/150224220013.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1038/s41467-018-06157-6,Biology_417,"The researchers determined that, while climate change likely has been and will be a factor in the decline of some local populations such as in the Rocky Mountain West -- where the effect of a warming climate seems to be more severe for amphibians -- it is not responsible for the current declines that are occurring.","While we demonstrate that amphibian communities are sensitive to changes in climate, our results suggest that changing climate is not the proximate cause for ongoing assemblage-wide declines that have been observed in North American amphibians.","For example, they found that less precipitation during breeding seasons generally has a negative effect on amphibian populations, while less snowfall during winter may benefit many populations. The researchers determined that, while climate change likely has been and will be a factor in the decline of some local populations such as in the Rocky Mountain West -- where the effect of a warming climate seems to be more severe for amphibians -- it is not responsible for the current declines that are occurring. ""It depends on the location whether habitat loss, disease, contaminants, climate, or a combination of these local factors is the culprit,"" she said.","For example, we found that summer drought has the strongest impact in warm and dry regions, decreased snowfall has a smaller effect in eastern compared to western North America, and winter warming is predicted to decrease species richness for all species groups except tree frogs. While we demonstrate that amphibian communities are sensitive to changes in climate, our results suggest that changing climate is not the proximate cause for ongoing assemblage-wide declines that have been observed in North American amphibians. Instead, we find that recent change in climate is a strong predictor of why local species richness is declining more quickly in some regions and that positive effects of climate may be buffering declines in other regions.","[4.0, 4.0, 5.0, 4.0, 3.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=37215274368&p=1pl&v=1&x=fx948_m_mGeC95JrU6Jwsg
10.1038/s41467-018-05738-9,Biology_419,"""Within my lifetime, my children's lifetime, it should be ramping up.","We acknowledge that present-day emissions associated with abrupt thaw may be conservative since gross lake-area increases in some regions are higher (e.g., > 50% in Quebec 85 and > 23% in West Siberia 86 ), potentially due to hydrological changes in addition to permafrost thaw.","""We don't have to wait 200 or 300 years to get these large releases of permafrost carbon. ""Within my lifetime, my children's lifetime, it should be ramping up. It's already happening but it's not happening at a really fast rate right now, but within a few decades, it should peak.""","This range of gross lake expansion is comparable to our observation of gross lake-area increase in northern and western Alaska (i.e., 1999-2014, 1.1-1.7% gross lake area increase upscaled to 5-7% assuming similar expansion/formation rates over the past 60 years; Supplementary Table 3, Fig. We acknowledge that present-day emissions associated with abrupt thaw may be conservative since gross lake-area increases in some regions are higher (e.g., > 50% in Quebec 85 and > 23% in West Siberia 86 ), potentially due to hydrological changes in addition to permafrost thaw. The formation/expansion of new thermokarst-lake areas and subsequent sublake talik growth is not the only mechanism of abrupt permafrost degradation making newly thawed permafrost carbon available for microbial decomposition.","[3.0, 2.0, 1.0, 1.0, 4.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=37091509163&p=1pl&v=1&x=OOO_-fXHaVKPAQqiGUPVbg
10.1038/emboj.2013.236,Biology_421,"""The ZNF281 promoter sequence contains several binding sites for the SNAIL protein, which is in turn involved in implementing the EMT triggered by c-MYC, and we were able to show that the metastasis-promoting role of SNAIL depends on its ability to bind to the ZNF281 promoter,"" says Hermeking.","Furthermore, c-MYCinduced SNAIL could repress miR-34, which would contribute to increased ZNF281 expression.","Their findings revealed that ZNF281 is at the hub of a complex functional network that indeed has a significant influence on tumor metastasis. ""The ZNF281 promoter sequence contains several binding sites for the SNAIL protein, which is in turn involved in implementing the EMT triggered by c-MYC, and we were able to show that the metastasis-promoting role of SNAIL depends on its ability to bind to the ZNF281 promoter,"" says Hermeking. In addition, the researchers demonstrated that the ZNF281 protein itself activates SNAIL, thus setting up a positive feedback loop that further increases its own expression.","The absence of c-MYC binding sites in the promoter region of ZNF281 implies the existence of alternative regulatory mechanisms. Furthermore, c-MYCinduced SNAIL could repress miR-34, which would contribute to increased ZNF281 expression. Alternatively, the association of c-MYC protein with ZNF281 may inhibit the turnover of ZNF281.","[3.0, 4.0, 3.0, 4.0, 2.0]",Biology,train,3.2,news,http://www.sciencedaily.com/releases/2013/11/131104092603.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1111/ele.12236,Biology_423,All these relations together form a robust network of interactions between plants and pollinators.,The extent to which pollinators interact with the same plant species increases with connectance and/or nestedeness.,"All these relations together form a robust network of interactions between plants and pollinators. These networks have a characteristic structure that is similar in very different natural landscapes, such as rainforests and river deltas, as well as in human-dominated landscapes with orchards, fields and meadows. Plants and pollinators take a position within those networks that makes the benefit from their mutual relationships for each species individually, and for all plants and pollinators together, as large as possible.",Our results can be understood intuitively by considering the 'net effects' of species on each other and the way in which these effects are mediated by the topology of mutualistic networks. The extent to which pollinators interact with the same plant species increases with connectance and/or nestedeness. A high nestedness of the mutualistic network may therefore promote the occurrence of indirect positive effects between pollinators.,"[3.0, 4.0, 4.0, 3.0, 4.0]",Biology,train,3.6,news,http://www.technology.org/2014/01/07/robust-network-insect-pollinators-may-collapse-suddenly-study-finds/
10.1073/pnas.1519508113,Biology_424,"""The genetic diversity we have discovered, thanks to restocking from wild 'ghost' dromedary populations, is quite remarkable in the history of its domestication,"" adds Almathen.","Given the environmental context in which the wild dromedary would have evolved, it can be assumed that its native distribution and population size were generally quite restricted compared with the ancestral ranges of other livestock species before domestication.","""The genetic diversity we have discovered, thanks to restocking from wild 'ghost' dromedary populations, is quite remarkable in the history of its domestication,"" adds Almathen. ""It underlines the animal's potential to adapt sustainably to future challenges of expanding desert areas and global climate change."" ""Our analysis of this extensive dataset actually revealed that there is very little defined population structure in modern dromedaries,"" says Olivier Hanotte, professor of genetics and conservation at the University of Nottingham.","S5 ) and increasingly disjointed before the global extinction of the wild populations less than two millennia after the appearance of the domestic form ) . Given the environmental context in which the wild dromedary would have evolved, it can be assumed that its native distribution and population size were generally quite restricted compared with the ancestral ranges of other livestock species before domestication. As suggested by the environmental context of the archaeological findings, the wild ancestors of C. dromedarius spent part of their lives foraging in coastal habitats including mangroves .","[3.0, 2.0, 4.0, 3.0]",Biology,train,3.0,news,http://www.futurity.org/domestic-dromedary-camel-1158862-2/
10.1038/s41564-019-0426-5,Biology_425,Developing a fundamental understanding of the biodiversity of the activated sludge microbiome in relationship to performance is critical to advancing and optimizing this key technology for maintaining environmental health.,Meta-analyses with global datasets associate the activated sludge microbiomes most closely to freshwater populations.,"This study is novel in several ways: (1) it reports the first comprehensive, highly coordinated effort to examine the global diversity and biogeography of the activated sludge microbiome; (2) it documents a highly diverse activated microbiome, containing up to one billion microbial phylotypes comprise of novel species; (3) it identifies the core global taxa of activated sludge microbial communities that are linked to activated sludge performance; (4) it reveals that the activated sludge microbiome is distinct from microbiomes in other habitats; and (5) it provides an understanding of the mechanisms driving the composition and functions of the activated sludge communities. Developing a fundamental understanding of the biodiversity of the activated sludge microbiome in relationship to performance is critical to advancing and optimizing this key technology for maintaining environmental health. ""This unprecedented global sampling effort yielded new insight into the microbiology of activated sludge,"" said Bruce Rittmann, director, Biodesign Swette Center for Environmental Biotechnology, Arizona State University.","Despite this high diversity, activated sludge has a small, global core bacterial community (n = 28 operational taxonomic units) that is strongly linked to activated sludge performance. Meta-analyses with global datasets associate the activated sludge microbiomes most closely to freshwater populations. In contrast to macroorganism diversity, activated sludge bacterial communities show no latitudinal gradient.","[3.0, 2.0, 4.0, 3.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=39214953502&p=1pl&v=1&x=KnsyRGsniTDUhbLA3M7vMw
10.1016/j.cell.2018.10.050,Biology_426,"After 18 of 20 days of gestation, the mice developed the same symptoms that women with preeclampsia experience: increased blood pressure and protein in their urine.","Pregnant Tg-AT1B2 mice developed symptoms of preeclampsia as evidenced by hypertension on day 18 of pregnancy, proteinuria, low platelet count, and increased levels of circulating sFlt1 ( Figures 4A-4D ).","""Every day that the fetus has left to develop in the mother's womb counts when it comes to premature births."" After 18 of 20 days of gestation, the mice developed the same symptoms that women with preeclampsia experience: increased blood pressure and protein in their urine. Conversely, when researchers reduced the receptor heterodimers, it delayed preeclampsia.","Together, these data demonstrate that AT1cer and B2eYFP are mainly forming heteromers on vascular smooth muscle cells isolated from double-transgenic Tg-AT1B2 mice. Pregnant Tg-AT1B2 mice developed symptoms of preeclampsia as evidenced by hypertension on day 18 of pregnancy, proteinuria, low platelet count, and increased levels of circulating sFlt1 ( Figures 4A-4D ). Circulating sFlt1 levels of pregnant Tg-AT1B2 mice on day 18 of pregnancy were comparable to serum sFlt1 and sFLT1 levels of other mouse models of preeclampsia and human patients with severe preeclampsia (Holobotovskyy et al., 2015; De Vivo et al., 2008; .","[4.0, 5.0, 4.0, 4.0]",Biology,train,4.25,news,https://www.futurity.org/preeclampsia-pregnancy-1955712/
10.1073/pnas.1301764110,Biology_427,"""TfR1 plays a role in HCV infection at the level of glycoprotein-mediated entry, acts after CD81 and is possibly involved in HCV particle internalization,"" said Danyelle Martin, the first author of the study who performed this research as part of her Ph.D work at University of Illinois at Chicago (UIC) and is now manager of the newly established Clinical Research Office Biobank at Loyola University Medical Center.","Although not a robust assay, analogous to previous reports, we observed a threefold increase in HCVcc binding to CHO cells expressing human SRBI than to parental CHO cells, and this binding was more pronounced than that detected on CHO cells expressing CD81.","""It creates a key building block toward finding a medical solution to Hepatitis C.""

The new study is part of a project initially directed at understanding how HCV may disrupt cellular iron homeostasis. ""TfR1 plays a role in HCV infection at the level of glycoprotein-mediated entry, acts after CD81 and is possibly involved in HCV particle internalization,"" said Danyelle Martin, the first author of the study who performed this research as part of her Ph.D work at University of Illinois at Chicago (UIC) and is now manager of the newly established Clinical Research Office Biobank at Loyola University Medical Center. ""More studies will need to be done to determine if and how the interaction between TfR1 and HCV leads to the hepatic iron overload seen in HCV infected patients.""","HCV Particle Binds to TfR1. Although not a robust assay, analogous to previous reports, we observed a threefold increase in HCVcc binding to CHO cells expressing human SRBI than to parental CHO cells, and this binding was more pronounced than that detected on CHO cells expressing CD81. Likewise, CHO cells expressing TfR1 exhibited greater than a threefold increase in HCVcc binding over background (Fig.","[2.0, 3.0, 1.0, 4.0]",Biology,train,2.5,news,http://www.sciencedaily.com/releases/2013/06/130610192611.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-017-00597-2,Biology_428,"When exposed to drugs which cause no disturbance in normal embryos, their brainless counterparts went on to develop severe birth defects, such as bent spinal cords and tails, which made it clear that the brain also acts as a barrier against potentially dangerous substances.","The effect is brain-specific, as removal of other body regions does not induce this effect.","The alteration led to abnormal development of the muscles and the peripheral nervous system, indicating the importance of the brain for embryogenesis even in distant regions of the body. When exposed to drugs which cause no disturbance in normal embryos, their brainless counterparts went on to develop severe birth defects, such as bent spinal cords and tails, which made it clear that the brain also acts as a barrier against potentially dangerous substances. ""Our data suggest that the brain exercises these functions using electrical and chemical channels that communicate locally and at a distance.","Here we show that the early morphogenesis and patterning of trunk muscle structure and innervation in animals developing without a brain are highly abnormal. The effect is brain-specific, as removal of other body regions does not induce this effect. The brain is not only required for normal development, but also exerts a protective effect, ameliorating the effects of teratogenic drugs which are made notably worse in brainless embryos.","[2.0, 1.0, 2.0, 2.0, 2.0]",Biology,train,1.8,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/7ipa-L3-lPo/
10.1038/s41467-019-09863-x,Biology_43,"""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost.",These findings stemming from the nonlinearities both in the PCF and SAF have been overlooked in climate policy studies so far (Supplementary Note 5) .,"What's needed, he said, is urgency and political will. ""Even at 1.5degC to 2degC [warming], there are impacts and costs due to thawing permafrost. But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev.",This means IAMs that do not include the PCF and assume a constant SAF will underestimate GMST by between 0.1 and 0.2 C for all but the highest emissions scenarios. These findings stemming from the nonlinearities both in the PCF and SAF have been overlooked in climate policy studies so far (Supplementary Note 5) . Implications for the total economic effect of climate change.,"[3.0, 1.0, 2.0, 1.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1098/rspb.2014.1887,Biology_430,"""We can tell that there is something going through the filefish diet that's making the fish smell enough like the coral to confuse the crabs,"" Booker said.","Crabs also exhibited a similar preference for the odour of filefish fed their preferred coral and odour directly from that coral, suggesting a close chemical match.","The filefish smelled so strongly of coral that sometimes the crabs were attracted to the fish instead of coral, when given a choice between the two. ""We can tell that there is something going through the filefish diet that's making the fish smell enough like the coral to confuse the crabs,"" Booker said. When the filefish diet didn't match the corals in the tank, the cod were restless, suggesting that they smelled food.","Crabs preferred the odour of filefish fed their preferred coral over the odour of filefish fed a non-preferred coral, suggesting coralspecific dietary elements that influence odour are sequestered. Crabs also exhibited a similar preference for the odour of filefish fed their preferred coral and odour directly from that coral, suggesting a close chemical match. This is, we believe, the first evidence of diet-induced chemical crypsis in a vertebrate.","[5.0, 3.0, 4.0, 2.0]",Biology,train,3.5,news,http://www.sciencedaily.com/releases/2014/12/141211115524.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.anbehav.2019.04.011,Biology_431,"Age And Reproduction

However, even if the older males were essentially more attractive to the females, they mated less frequently than the younger ones.",They invoked potential declines in fertility and increases in mutation load with age (as discussed above) and argued that survival to old age is not an indicator of genetic quality.,"On the other hand, those who choose the younger males may have done so because their genes might not have accumulated mutations that can be passed onto their offspring. Age And Reproduction

However, even if the older males were essentially more attractive to the females, they mated less frequently than the younger ones. That said, the researchers did not find any relationship between the male's age and the number of offspring they produced.","dismissed the potential role of age as an indicator of high genetic quality. They invoked potential declines in fertility and increases in mutation load with age (as discussed above) and argued that survival to old age is not an indicator of genetic quality. In contrast, a simulation model by supported the possibility of age acting as a good-genes indicator.","[2.0, 1.0, 2.0, 3.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=39314343708&p=1pl&v=1&x=7oTJ7EvTH4_gmwHLuirLRg
10.1038/s41467-018-07273-z,Biology_433,The damage caused by the heatwave affected the sons of overheated males.,"Sons of males that had been exposed to a single heatwave in the previous generation showed a 25% reduction in mating success and subsequent offspring production, compared with controls whose fathers had not experienced heatwave conditions ( Fig.","RELATED Inbred animals struggle to adapt to environmental changes

When females affected by the heatwave were allowed to mate with males unexposed to heat, reproductive success returned to normal, suggesting sperm are harmed by rising temperatures. The damage caused by the heatwave affected the sons of overheated males. Subsequent male generations also produced fewer offspring.","4c, d , e, f). Sons of males that had been exposed to a single heatwave in the previous generation showed a 25% reduction in mating success and subsequent offspring production, compared with controls whose fathers had not experienced heatwave conditions ( Fig. Critically, these same transgenerational effects were also evident when mature inseminated sperm alone had experienced the same conditions within the female: sons fertilised by heatwave-exposed spermatozoa in the female tract suffered 25 to 40% reductions in their reproductive output and mating success, compared with sons from parents where the mother had experienced the heatwave before mating and sperm storage, or controls where no heatwaves were experienced ( Fig.","[2.0, 4.0, 4.0, 4.0]",Biology,train,3.5,news,http://ct.moreover.com/?a=37679732070&p=1pl&v=1&x=7vVto0DNdsP8w6P0QNVRYQ
10.1186/s13059-018-1616-9,Biology_434,"The gut microbiomes from Tanzanian populations tended to have a higher number of microbes in each sample, and individuals tended to share similar microbial profiles.","From this observation, we infer that the gut bacteria are phylogenetically more distinct between groups defined by region (country) than by subsistence practice.","Notably, the Botswanan samples differed from the Tanzanian ones. The gut microbiomes from Tanzanian populations tended to have a higher number of microbes in each sample, and individuals tended to share similar microbial profiles. In Botswana, on the other hand, samples tended to have fewer microbial species overall, and individuals' microbiomes tended to be more different from one another.","Comparing the magnitudes of difference between subsistence groups and geographic groups, we therefore find that the bacterial compositional difference between Tanzania and Botswana (a geographic grouping) is larger than between any of the African subsistence groups (both unweighted and weighted UniFrac F-statistics). From this observation, we infer that the gut bacteria are phylogenetically more distinct between groups defined by region (country) than by subsistence practice. The Hadza and Maasai had significantly larger unweighted UniFrac distances between sexes than expected by chance (PERMA-NOVA p value < 0.05) ( Fig.","[4.0, 3.0, 3.0, 4.0]",Biology,train,3.5,news,http://ct.moreover.com/?a=38332540468&p=1pl&v=1&x=vRQbsh6_d3tS0IWvnU7XjA
10.1016/j.cub.2014.04.044,Biology_435,Functional MR imaging taken while the animals received either a juice reward or VTA stimulation revealed that both induced activation of brain regions that previous studies in humans and other primates have associated with reward signaling by means of the neurotransmitter dopamine.,"The other regions displaying juice and VTA-EM activations were mainly somatosensory and motor and/or premotor regions (areas 1 and 2, area 3a and 3b, frontal area 1 [F], F3, F5a, F5c, rostral inferior parietal lobule [PF] , and secondary somatosensory cortex [SII] ).",Subsequent repetition of the preference test showed that the animal's choice had shifted to the image reinforced by VTA stimulation. Functional MR imaging taken while the animals received either a juice reward or VTA stimulation revealed that both induced activation of brain regions that previous studies in humans and other primates have associated with reward signaling by means of the neurotransmitter dopamine. The level of VTA stimulation required to activate these structures was considerably less than the amount required to reinforce or change behavior in the earlier experiments.,"This correspondence confirms that VTA-EM activates most of the structures typically activated by natural reinforcers. The other regions displaying juice and VTA-EM activations were mainly somatosensory and motor and/or premotor regions (areas 1 and 2, area 3a and 3b, frontal area 1 [F], F3, F5a, F5c, rostral inferior parietal lobule [PF] , and secondary somatosensory cortex [SII] ). Although activation of these structures in the juice experiment could result from the motor component of juice consumption, there were no differences in the juice administered temporally surrounding VTA-EM and the no VTA-EM events (see Supplemental Experimental Procedures).","[4.0, 4.0, 3.0, 4.0]",Biology,train,3.75,news,http://www.healthcanal.com/brain-nerves/51419-activation-of-brain-region-can-change-a-monkey-s-choice.html
10.1111/gcb.13160,Biology_436,"The new report addresses this need by providing a comprehensive overview of current and projected future drought impacts on forests nationwide, how they vary by region, and which management practices could help partially mitigate problems.","Trees may be susceptible to drought-induced growth declines and mortality in two size/density situations, 1) at high-density conditions approaching the maximum size/density relationship, and 2) at low-density conditions conducive to the development of high levels of leaf area that promote canopy and root architecture that can put individual trees at risk.","Given the high degree of uncertainty in our understanding of how forest species and stands adapt to rapid change, it's going to be difficult to anticipate the type of forests that will be here in 20 to 40 years."" The new report addresses this need by providing a comprehensive overview of current and projected future drought impacts on forests nationwide, how they vary by region, and which management practices could help partially mitigate problems. The paper also identifies critical knowledge gaps that hinder scientists' ability to predict the pace and extent of future effects.","Fire suppression can lead to a 'mesophication' as forest canopies close and may explain why oak regeneration appears to decline relative to that of red (Acer rubrum) and sugar (Acer saccharum) maples in recent decades . Trees may be susceptible to drought-induced growth declines and mortality in two size/density situations, 1) at high-density conditions approaching the maximum size/density relationship, and 2) at low-density conditions conducive to the development of high levels of leaf area that promote canopy and root architecture that can put individual trees at risk. Increased vulnerability of trees and forests to water stress and mortality risk from warmer droughts is a global phenomenon, well illustrated in the western U.SA.","[3.0, 3.0, 2.0, 3.0, 2.0]",Biology,train,2.6,news,http://www.futurity.org/drought-forests-1110442-2/
10.1126/science.aat4082,Biology_438,The fact that the Western corn rootworm is able to perceive iron complexes and to adjust its dietary behavior accordingly is also relevant for the understanding of food chains.,We identify an iron transporter that allows the corn rootworm to benefit from complexes between iron and benzoxazinoids.,"These lines were essential for the identification of the benzoxazinoid that - after binding to iron - forms the compound that the rootworm recognizes and uses as a cue for plant selection. The fact that the Western corn rootworm is able to perceive iron complexes and to adjust its dietary behavior accordingly is also relevant for the understanding of food chains. We therefore expect that other higher organisms also have the ability to perceive biologically available forms of trace elements and to ingest them to improve their nutrient balance,"" says Matthias Erb.","We show that the root-feeding larvae use complexes between iron and benzoxazinoid secondary metabolites to identify maize as a host, to forage within the maize root system, and to increase their growth. We identify an iron transporter that allows the corn rootworm to benefit from complexes between iron and benzoxazinoids. In addition, root-feeding WCR larvae prefer benzoxazinoidproducing maize plants and require benzoxazinoids to identify crown roots as the preferred feeding site (6) .","[4.0, 4.0, 4.0, 3.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=34844174640&p=1pl&v=1&x=pe-ec8i21uz-JMST2-ud4w
10.1038/nature13379,Biology_439,"But the overall result was identical: the gene was activated, and appeared to drive tumour formation.","These findings were validated in an independent series of medulloblastomas (n 5 156) by immunohistochemical analysis, confirming mutually exclusive GFI1 and GFI1B expression that contributed to 41% and 10% of group 3 and group 4 cases analysed, respectively (Extended Data  Fig.","GFI1B and GFI1 sit on different chromosomes, and interestingly, the DNA rearrangements affecting GFI1 put it next to enhancers sitting on yet other chromosomes. But the overall result was identical: the gene was activated, and appeared to drive tumour formation. When they inserted those modified cells into the brains of healthy mice, the rodents developed aggressive, metastasising brain tumours that closely resemble Group 3 medulloblastoma in humans.","Collectively, GFI1 and GFI1B expression was observed in 25% and 5% of group 3 and group 4 medulloblastomas, respectively (Extended Data Fig. These findings were validated in an independent series of medulloblastomas (n 5 156) by immunohistochemical analysis, confirming mutually exclusive GFI1 and GFI1B expression that contributed to 41% and 10% of group 3 and group 4 cases analysed, respectively (Extended Data  Fig. 4) .","[4.0, 2.0, 2.0, 1.0]",Biology,train,2.25,news,http://www.healthcanal.com/cancers/52286-cancer-by-remote-control.html
10.1016/j.cell.2018.04.034,Biology_44,"""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation.",CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ).,"More study is needed to understand this. ""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation. ""The Prostate Cancer Foundation is proud to have funded this team, which continues to make foundational strides in identifying actionable genomic mutations in prostate cancer and using this information to identify new classes of precision treatments that can be used to improve the lives of men with prostate cancer.""","However, our data, and the observations made previously in CDK12 mutant ovarian tumors , are inconsistent with that model. CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ). Overall, the genomic phenotypes of HR and CDK12 deficiency are clearly distinct.","[2.0, 2.0, 1.0, 3.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1038/s41598-019-39601-8,Biology_440,"The researchers found that the sex ratio of the wild bees became more male biased as urbanization increased, mainly driven by a decline in medium- and large-bodied ground-nesting female bees.",Analyses show no qualitative differences with bumble bees removed: OSR still becomes less female-biased as urbanization increases (Table S3 ).,"advertisement

Seventy-four percent of the captured bees belonged to species that nest underground (ground-nesting), and the rest belonged to species that nest above ground in cavities or hollow tree stems. The researchers found that the sex ratio of the wild bees became more male biased as urbanization increased, mainly driven by a decline in medium- and large-bodied ground-nesting female bees. An alternative explanation for the observed sex ratio shift has to do with urbanization-induced changes in sex allocation by bees.","made up a large portion of our sample set; most bumble bee species are eusocial, and as such may experience controls on OSR that differ substantially from other bees (see Introduction). Analyses show no qualitative differences with bumble bees removed: OSR still becomes less female-biased as urbanization increases (Table S3 ). As with bee abundance data, floral richness and area metrics were significantly overdispersed, so quasi-Poisson distributions were used to account for overdispersion.","[2.0, 2.0, 4.0, 5.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=38704408876&p=1pl&v=1&x=SqcIooOUdWTnFLEX-JoPvw
10.1073/pnas.1619294114,Biology_441,"Furthermore, examination of aged mice showed dramatically reduced levels of Cbf-beta in bone marrow cells, as compared to younger mice.","Wnt/ β-catenin directs mesenchymal cell commitment to the osteogenic lineage and prevents adipogenic differentiation, resulting in increased new bone formation .","The UAB researchers found that a protein called Cbf-beta plays a critical role in maintaining the bone-producing cells. Furthermore, examination of aged mice showed dramatically reduced levels of Cbf-beta in bone marrow cells, as compared to younger mice. Thus, they propose, maintaining Cbf-beta may be essential to preventing human age-associated osteoporosis that is due to elevated creation of fat cells.","Runx/Cbfβ Complex Promotes Wnt10b/β-Catenin Signaling and Inhibits c/ebpa Expression to Inhibit Lineage Switch into Adipocytes. Wnt/ β-catenin directs mesenchymal cell commitment to the osteogenic lineage and prevents adipogenic differentiation, resulting in increased new bone formation . Interestingly, Wnt10b is downregulated in Cbfβ-deficient cells and tissues, and ChIP plus promoter activity assay showed that Wnt10b is up-regulated by Cbfβ f/f Prx1-Cre calvarial cells cultured in osteogenic medium or osteogenic medium supplemented with Wnt3L conditional medium, normalized to hprt1.","[3.0, 2.0, 2.0, 4.0]",Biology,train,2.75,news,http://healthmedicinet.com/news/researchers-describe-mechanism-that-underlies-age-associated-bone-loss/
10.1038/s41467-019-09786-7,Biology_442,"Taken together, molecular changes at this site may explain why psychosis brought on by dopamine frequently is accompanied by a disruption of brain synapses, a devastating double-hit that promotes symptoms.","In the striatum, inactivation of the Igf2 enhancer led to a decrease in TH protein levels and in dopamine (p < 0.05; one-way ANOVA; Fig.","Their analyses revealed a cluster of epigenetic marks, which switch genes on and off, in an enhancer at a gene called IGF2, a critical regulator of synaptic development. Taken together, molecular changes at this site may explain why psychosis brought on by dopamine frequently is accompanied by a disruption of brain synapses, a devastating double-hit that promotes symptoms. The study controlled for genetic factors, sex, ethnicity, treatment history and lifestyle influences such as smoking, and the results were validated in experimental models of the disease.","7c ), supporting dysregulation of the TH-IGF2 locus in major psychosis. In the striatum, inactivation of the Igf2 enhancer led to a decrease in TH protein levels and in dopamine (p < 0.05; one-way ANOVA; Fig. 3d , e); this effect was not observed in the frontal cortex ( Supplementary Fig.","[2.0, 1.0, 1.0]",Biology,train,1.3333333333333333,news,http://ct.moreover.com/?a=39137370713&p=1pl&v=1&x=PNwbzWt6UWX8sdaXCuLTAA
10.1093/humupd/dmi047,Biology_443,Gaining knowledge on why some sperm fail while others succeed could provide better insight for researchers to find solutions in treating male infertility.,"Finally, diagnosis of the causes of infertility could be greatly improved if more were known of the means by which sperm travel through the female reproductive tract and the mechanisms that regulate the movement of sperm.","Accordingly, this coordinated rhythm of its head and tail will determine if it will be successful or not. Gaining knowledge on why some sperm fail while others succeed could provide better insight for researchers to find solutions in treating male infertility. The next step would be applying the model with the movement of a larger number of sperm cells.","This staggering difference almost certainly reflects our inability to adequately mimic in vitro the environment and sperm selection mechanisms of the female reproductive tract during natural unassisted conception. Again, clearly if we knew more of the basic biology that underpins these events in vivo then there is the potential for improvements to be made to IVF procedures that could impact on the clinical outcome. Finally, diagnosis of the causes of infertility could be greatly improved if more were known of the means by which sperm travel through the female reproductive tract and the mechanisms that regulate the movement of sperm.","[4.0, 5.0, 4.0, 4.0, 4.0]",Biology,train,4.2,news,http://www.universityherald.com/articles/70430/20170323/how-sperm-swims-revealed-in-simple-maths.htm
10.1016/j.cub.2011.10.032,Biology_444,"""But it's consistent with the dominant view that synesthesia is due to cross-connectivity between different brain areas.","functional role in synesthetic experience, plausibly because of maturation and cortical specialization of the visual system .","""The idea that synesthesia results from region-specific hyperexcitability is novel,"" Terhune says. ""But it's consistent with the dominant view that synesthesia is due to cross-connectivity between different brain areas. One possibility is that these highly excitable neurons might help produce the extra connections.""","However, at later developmental stages, visual cortical hyperexcitability appears no longer to exercise a direct Table S3 . functional role in synesthetic experience, plausibly because of maturation and cortical specialization of the visual system . Rather, our results indicate that hyperexcitability assumes a different role and acts as a source of noise in visual cortex, competing with other regions supporting synesthesia, such as V4 , and thereby modulates the signalto-noise ratio underlying the experience of synesthetic color photisms (see also Supplemental Discussion).","[3.0, 3.0, 2.0, 5.0, 2.0]",Biology,train,3.0,news,http://news.sciencemag.org/2011/11/overactive-neurons-may-tangle-senses
10.1038/s41467-019-08549-8,Biology_445,"""It suggests that our education systems should focus on cultivating both general and social intelligence to better equip groups to deal with complex, social-ecological challenges,"" said co-author Dr. Jacob Freeman, an assistant professor of anthropology at Utah State University.","This does not occur where both g and ToM are high, perhaps signaling the emergence of a more well developed group intelligence.","""Such people skills are important for managing shared resources."" The work points to a need for education in diverse types of intelligence. ""It suggests that our education systems should focus on cultivating both general and social intelligence to better equip groups to deal with complex, social-ecological challenges,"" said co-author Dr. Jacob Freeman, an assistant professor of anthropology at Utah State University.","Groups with high g and low ToM harvest faster and push the resource system closer to its breaking point following a change in resource growth rate. This does not occur where both g and ToM are high, perhaps signaling the emergence of a more well developed group intelligence. Our results are consistent with the idea that both individual level intelligence and functioning as social groups are important for humans to solve socialecological challenges.","[2.0, 5.0, 1.0, 4.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=38729478812&p=1pl&v=1&x=lewAZ9n3HFFbG3Md2srHiw
10.1016/j.cell.2013.04.015,Biology_447,"The old mice now had young hearts, while the young mice's hearts stayed strong.",The striking effect of a young circulation on old hearts was immediately apparent on visual inspection.,"After 4 weeks of connection to young mice, the five old mice's heart tissue had thinned and softened, looking just as spry and supple as the 2-month-olds'. The old mice now had young hearts, while the young mice's hearts stayed strong. But the team spent years trying to figure out why; it was often the topic of Lee and Wagers' weekly bike rides.","This strategy allowed us to monitor blood chimerism in the pairs; however, because old CD45.1+ mice are not commercially available, we used only CD45.2+ mice to generate isochronic old pairs. The striking effect of a young circulation on old hearts was immediately apparent on visual inspection. Hearts from old mice exposed to a young circulation (O-HP) for 4 weeks were noticeably smaller than hearts from O-IP mice.","[3.0, 1.0, 3.0, 2.0, 2.0]",Biology,train,2.2,news,http://news.sciencemag.org/2013/05/nineteenth-century-technique-turns-old-mouse-hearts-young
10.1016/j.cell.2018.07.032,Biology_448,"""While bacteria make this iron-scavenging compound for their own use, our research suggests that mammals--including humans--have learned over time to hijack it for their own benefit,"" said Han.","Given the symbiotic relationship between commensal E. coli and the host, one may speculate that an unknown beneficial mechanism has evolved in animals to use bacterial Ent for host iron homeostasis.","The new study challenges that paradigm, suggesting that enterobactin also binds to a protein called ATP synthase inside the host's mitochondria, drawing iron into the host's cells too. ""While bacteria make this iron-scavenging compound for their own use, our research suggests that mammals--including humans--have learned over time to hijack it for their own benefit,"" said Han. Oral antibiotics could potentially have the same impact, he says.","More importantly, this mechanism does not explain how host animals would cope with abundant Ent from non-infectious gut microbiota, of which enterobacteria are the most prevalent commensal microbes in both human and C. elegans . Given the symbiotic relationship between commensal E. coli and the host, one may speculate that an unknown beneficial mechanism has evolved in animals to use bacterial Ent for host iron homeostasis. In this study, by developing a unique and sensitive assay in C. elegans, we discovered an unexpected but logical role of bacterial Ent in supporting animal growth and iron level.","[5.0, 4.0, 2.0, 2.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=34896225587&p=1pl&v=1&x=PrRhbvMQXEClnkBdafQXuw
10.1016/j.cell.2013.08.015,Biology_449,This latest research uncovers Beclin 1 as one important way in which EGFR may derail the body's cancer-fighting autophagy machinery to increase tumor growth.,"However, when cells were treated with EGF and EGFR was phosphorylated, EGFR coimmunoprecipitated with Beclin 1.","""Our findings suggest that inactivation of autophagy may be a critically important factor in the progression of lung cancer."" This latest research uncovers Beclin 1 as one important way in which EGFR may derail the body's cancer-fighting autophagy machinery to increase tumor growth. A second finding in the new study related to chemotherapy resistance.","During growth in normal or serum-free media when no EGFR phosphorylation was observed, EGFR did not coimmunoprecipitate with Beclin 1 (Figure 1D ). However, when cells were treated with EGF and EGFR was phosphorylated, EGFR coimmunoprecipitated with Beclin 1. Thus, active phosphorylated EGFR interacts with a key component of the autophagy machinery, Beclin 1, in human NSCLC cells in a ligand-dependent manner.","[2.0, 3.0, 3.0, 3.0, 2.0]",Biology,train,2.6,news,http://www.sciencedaily.com/releases/2013/09/130918130504.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.cell.2013.08.004,Biology_45,"PhysOrg notes that body-clock ""disturbances"" have also been tied to mental disorders like schizophrenia, so the findings could have even broader implications.","As SIK1 acts to suppress the effects on light on the clock, this pathway presents a tractable target.","What we saw was the mice would actually advance their clock six hours within a day [rather than taking six days for untreated mice]."" PhysOrg notes that body-clock ""disturbances"" have also been tied to mental disorders like schizophrenia, so the findings could have even broader implications. (Click for another story related to sleep ... or lack thereof.)","In addition, SCRD is a common feature of both neuropsychiatric and neurodegenerative disease . As SIK1 acts to suppress the effects on light on the clock, this pathway presents a tractable target. (B) Phase-shifting responses to light are significantly larger following knockdown of Sik1 in the SCN (siSik1) when compared to nontargeting siRNA (siNT) controls (98 min versus 59 min, p = 0.036, Student's t test, n = 5).","[3.0, 1.0, 1.0]",Biology,train,1.6666666666666667,news,http://www.newser.com/story/173430/scientists-uncover-clue-to-jet-lag.html
10.1016/j.cub.2018.06.013,Biology_450,"At first, the birds didn't flee from the unfamiliar sounds.",Our work demonstrates that wild birds can learn socially to recognize previously unfamiliar sounds as alarm calls.,"""The current experiment shows that they can,"" and through the novel process of making associations between different sounds. At first, the birds didn't flee from the unfamiliar sounds. But after training, they often did flee to cover upon hearing the sounds.","Complementary studies of social learning in captivity would be useful in examining in detail the context in which different associations are formed. Our work demonstrates that wild birds can learn socially to recognize previously unfamiliar sounds as alarm calls. In our current experiment, learning could not be asocial because the unfamiliar sounds were never presented at the same time as predator models.","[5.0, 4.0, 2.0, 4.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=34706093653&p=1pl&v=1&x=yyRxno6iXBGL0a0HV6BjiQ
10.1038/s41467-018-06236-8,Biology_451,"While the study shows that epigenetic information transmitted by sperm is important for normal development, it does not directly address how the life experience of a father can affect the health of his descendants.",The finding that abnormal retention of an epigenetic memory of spermatogenesis compromises germline health 36 suggests that sperm epigenetic marking must be reset each generation.,"""These findings show that the DNA packaging in sperm is important, because offspring that did not inherit normal sperm epigenetic marks were sterile, and it is sufficient for normal germline development,"" Strome said. While the study shows that epigenetic information transmitted by sperm is important for normal development, it does not directly address how the life experience of a father can affect the health of his descendants. By demonstrating the importance of epigenetic information carried by sperm, the current study establishes that if the environment experienced by the father changes the epigenetics of sperm chromosomes, it could affect the offspring.","We speculate that multivalent marking in C. elegans sperm serves a different function than in zebrafish and mammalian sperm, namely to enable an epigenetic memory of spermatogenesis to be reset. The finding that abnormal retention of an epigenetic memory of spermatogenesis compromises germline health 36 suggests that sperm epigenetic marking must be reset each generation. Multivalent marking of chromatin domains may serve diverse functions depending on biological context, developmental tissue and stage, and organism.","[3.0, 3.0, 3.0, 3.0, 2.0]",Biology,train,2.8,news,http://ct.moreover.com/?a=37417051518&p=1pl&v=1&x=V6M54pbaYN-eW-ET3SYp-A
10.1111/j.1600-0706.2013.00620.x,Biology_452,It's the weather of the seasons on either side of winter that seem to have the biggest impact on long-tailed tit survival.,"Using our model to estimate historical survival rates indicates that recent spring warming has led to an upward trend in survival rates, which has probably contributed to the observed long-term increase in the UK long-tailed tit population.","The predictably cold winter months, however do not seem to play a role in the bird's death rate. It's the weather of the seasons on either side of winter that seem to have the biggest impact on long-tailed tit survival. ""However, it seems that in most years autumn weather plays a bigger role, perhaps acting as a filter that weeds out weaker birds before the real winter hits.""","There is little evidence for density dependence across the observed variation in population size. Using our model to estimate historical survival rates indicates that recent spring warming has led to an upward trend in survival rates, which has probably contributed to the observed long-term increase in the UK long-tailed tit population. Future climate change is predicted to further increase survival, under a broad range of carbon emissions scenarios and probabilistic climate change outcomes, even if precipitation increases substantially.","[4.0, 2.0, 4.0, 4.0]",Biology,train,3.5,news,http://www.natureworldnews.com/articles/6427/20140324/long-tailed-tit-may-benefit-from-climate-change.htm
10.1126/scitranslmed.3010760,Biology_453,"""This new technique provides a window into the fate of these T cells and has potential as an individualized biomarker for predicting and identifying rejection and tolerance in different types of transplant patients,"" said study leader Megan Sykes, MD, the Michael J. Friedlander Professor of Medicine, professor of microbiology & immunology and surgical sciences (in surgery), and director of the Columbia Center for Translational Immunology at CUMC.","The notion that some, but not all, deletion of donor-reactive clones in tolerant subjects may have reflected repertoire turnover was supported by analysis of third party-reactive T cells identified before transplant ( fig.","""This new technique provides a window into the fate of these T cells and has potential as an individualized biomarker for predicting and identifying rejection and tolerance in different types of transplant patients,"" said study leader Megan Sykes, MD, the Michael J. Friedlander Professor of Medicine, professor of microbiology & immunology and surgical sciences (in surgery), and director of the Columbia Center for Translational Immunology at CUMC. ""Furthermore, they are unpredictable and distinct for each transplant patient and donor."" Therefore, other explanations for long-term tolerance were needed.","A significant and sustained reduction in the detection of donor-reactive compared to all CD8 + clones was observed in subjects 2 and 4, suggesting antigen-driven loss of donor-reactive CD8 clones (Fig. The notion that some, but not all, deletion of donor-reactive clones in tolerant subjects may have reflected repertoire turnover was supported by analysis of third party-reactive T cells identified before transplant ( fig. S8 ), some of which showed posttransplant reductions.","[4.0, 2.0, 3.0, 3.0]",Biology,train,3.0,news,http://www.technology.org/2015/03/16/kidney-transplant-tolerance-mechanism-identified/
10.1016/j.celrep.2014.05.030,Biology_454,"It is the first direct molecular link found between the two health conditions and will open up new areas of research to identify drugs and explore lifestyle changes, such as dietary habits and exercises that could restore the level of NUCKS in the body.","Together, these results, especially the finding that nutrient overload exacerbates the metabolic phenotypes in the absence of NUCKS, suggest that NUCKS plays a role in metabolic homeostasis in vivo.","The NUCKS protein is an important clue for controlling diabetes development in obese individuals. It is the first direct molecular link found between the two health conditions and will open up new areas of research to identify drugs and explore lifestyle changes, such as dietary habits and exercises that could restore the level of NUCKS in the body. Having identified this protein, we are now a step closer towards removing one of these complications from individuals suffering from obesity.""","Consistent with the obese phenotype, leptin levels were elevated while those of adiponectin were decreased in HFD-fed NUCKS KO mice ( Figure S3G and S3H) . Together, these results, especially the finding that nutrient overload exacerbates the metabolic phenotypes in the absence of NUCKS, suggest that NUCKS plays a role in metabolic homeostasis in vivo. There was no difference in resting or fasting glucose levels between the two groups, but resting insulin levels were higher in NUCKS KO mice compared with WT mice (Figures S4A and S4B ; data not shown).","[4.0, 3.0, 2.0, 4.0]",Biology,train,3.25,news,http://www.sciencedaily.com/releases/2014/06/140630094850.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.ccell.2015.05.009,Biology_456,"But when the researchers treated the resistant cells with the SYK inhibitor fostamatinib, they were able to increase the paclitaxel sensitivity of the cells.","We found that SYK inhibitors stabilized microtubules through dephosphorylation of microtubule and microtubule-associated proteins, a mechanism that is distinct from paclitaxel.","The scientists then analyzed 25 different ovarian cancer cell lines in the laboratory and discovered that the higher the amount of active SYK in the cell lines, the more resistant those cells were to paclitaxel treatment. But when the researchers treated the resistant cells with the SYK inhibitor fostamatinib, they were able to increase the paclitaxel sensitivity of the cells. Fostamatinib's effect on microtubules seems to increase the stabilizing effect of paclitaxel, even in resistant cells, which in turn may prevent cancer cells from proliferating, said Yu Yu, PhD, a postdoctoral fellow at The Johns Hopkins University School of Medicine.","Importantly, inhibition of SYK sensitizes ovarian cancer cells to paclitaxel treatment via enhancing microtubule stability. We found that SYK inhibitors stabilized microtubules through dephosphorylation of microtubule and microtubule-associated proteins, a mechanism that is distinct from paclitaxel. As a result, SYK inhibitor and paclitaxel formed a synergistic cytotoxic effect in tumor cells, especially in those that were paclitaxel-resistant.","[5.0, 2.0, 3.0, 3.0]",Biology,train,3.25,news,http://www.oncologynurseadvisor.com/fostamatinib-paclitaxel-combination-may-shrink-ovarian-cancers/article/427125/
10.1111/ecog.03303,Biology_457,The overwhelming loss of prey suggests that it could have been a major key in the extinction of the big cats.,A significant positive correlation was recorded between the number of prey species lost and the number of large-felid species lost from a cell.,"The overwhelming loss of prey suggests that it could have been a major key in the extinction of the big cats. If all of the current threatened and declining prey species in the big cat natural ranges suddenly went extinct today, the Africal lion would be left with only 39 percent of their prey species. The Sunda clouded leopard would have only 37 percent.","In total, 86% of cells recorded at least one additional felid species in our present-natural counterfactual, and up to 4-5 more large-felid species in 10% of the cells. A significant positive correlation was recorded between the number of prey species lost and the number of large-felid species lost from a cell. Our results draw attention to the continuation of a trend of megafauna decline that began with the emergence of hominins in the Pleistocene.","[2.0, 5.0, 4.0, 4.0]",Biology,train,3.75,news,http://www.natureworldnews.com/articles/37955/20170511/the-path-to-extinction-african-lions-face-same-threats-that-wiped-out-big-cats-during-the-ice-age.htm
10.1007/s00239-015-9672-1,Biology_458,"TrpRS and TyrRS are more closely related to each other than to any other protein, indicating that they evolved from the same ancestor protein.","Importantly, the inferred absence of Trp within the paralog ancestor does not seem to be a consequence of broad selection against including Trp within TrpRS descendant lineages.","""By definition, anything pre-LUCA lies beyond the deepest split in the tree,"" he said. TrpRS and TyrRS are more closely related to each other than to any other protein, indicating that they evolved from the same ancestor protein. Sometime before LUCA, that parent protein mutated slightly to produce these two new proteins with distinct functions.","Four Trp ML sites are acquired on the branch leading to the TyrRS bacterial ancestor, two on the branch leading to the TyrRS crenarchaeal/eukaryal ancestor, two on the branch leading to the TrpRS bacterial ancestor, and one each on branches leading to the TyrRS euryarchaeal ancestor, and TrpRS euryarchaeal, crenarchaeal, and eukaryal ancestors. Importantly, the inferred absence of Trp within the paralog ancestor does not seem to be a consequence of broad selection against including Trp within TrpRS descendant lineages. Rather, Trp acquisition appears to be near-universal across major groups (Fig.","[3.0, 2.0, 2.0]",Biology,train,2.333333333333333,news,http://www.scientificamerican.com/article/how-structure-arose-in-the-primordial-soup/
10.1002/ajp.22168,Biology_459,"From a practical standpoint, caretakers of chimpanzees living in zoos or elsewhere can now tailor individualized care based on each animal's personality thereby improving animal welfare.""","There was a positive correlation between play behavior and Openness, as has been found previously for the trait ""curious"" .","""From an academic standpoint, the findings can inform investigations into the evolution of personality. From a practical standpoint, caretakers of chimpanzees living in zoos or elsewhere can now tailor individualized care based on each animal's personality thereby improving animal welfare."" The study of chimpanzee personality is not novel; however, according to the authors, previous instruments designed to measure personality left a number of vital questions unanswered.","Openness, which includes traits such as intelligent, inquisitive, human oriented, and inventive, had mixed predictive validity. There was a positive correlation between play behavior and Openness, as has been found previously for the trait ""curious"" . However, with Openness, there was also a positive correlation with submissive behavior and negative correlations with proximity and social grooming behaviors, none of which had been seen in previous studies .","[1.0, 3.0, 2.0, 1.0, 1.0]",Biology,train,1.6,news,http://www.sciencedaily.com/releases/2013/06/130603135521.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.3945/jn.113.188441,Biology_46,"One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this.""","The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","Some South Koreans are a little steamed--and defensive--about the study's findings. One man tells the AP, while guzzling ramen: ""There's no way any study is going to stop me from eating this."" Love for the instant noodle spans generations--it reminds the elderly of post-Korean War recovery and for the young and busy, it's quick and cheap.","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age. Our study had several limitations.","[2.0, 1.0, 1.0, 2.0]",Biology,train,1.5,news,http://www.newser.com/story/192784/new-heart-disease-culprit-ramen.html
10.1098/rspb.2013.3122,Biology_460,"Rather, their physiological differences enabled them to branch out and take advantage of other food resources in ways that brachiopods simply couldn't follow.","This finding holds even when restricting the comparison to bivalves that, like all brachiopods, are suspension feeders (electronic supplementary material, figure S1 ).","""What we see is that more mobile organisms tend to be better in the post-Paleozoic,"" Payne said. The new findings cast the fate of the two groups in a new light: Bivalves didn't outcompete brachiopods by getting better at obtaining the food sources that the two groups shared. Rather, their physiological differences enabled them to branch out and take advantage of other food resources in ways that brachiopods simply couldn't follow.","Although brachiopods were taxonomically and numerically dominant in Palaeozoic oceans, bivalves already used as much or more energy (figures 1 and 2). This finding holds even when restricting the comparison to bivalves that, like all brachiopods, are suspension feeders (electronic supplementary material, figure S1 ). When including genera with known stratigraphic ranges but lacking occurrences recorded in the PaleoDB, the transition to bivalve metabolic dominance occurs approximately 350 Ma (electronic supplementary material, figure S1 ).","[2.0, 3.0, 2.0, 2.0, 2.0]",Biology,train,2.2,news,http://www.sciencedaily.com/releases/2014/03/140326092635.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.7717/peerj.417,Biology_461,"In the study, which included Yerkes researchers Frans de Waal, PhD, Matt Campbell, PhD, and Tim Eppley, Suchak found the chimpanzees spontaneously cooperated 3,565 times over the course of 94 one-hour sessions.","The chimpanzees succeeded with significantly fewer pulls per success (e.g., higher efficiency) during the proficiency phase (Mixed Measures ANOVA: F 1,7 = 16.83, p = 0.005, Fig.","This finding, which addresses long-standing doubt about the level of cooperation chimpanzees are able to spontaneously achieve or understand, is published in the June 12 issue of PeerJ. In the study, which included Yerkes researchers Frans de Waal, PhD, Matt Campbell, PhD, and Tim Eppley, Suchak found the chimpanzees spontaneously cooperated 3,565 times over the course of 94 one-hour sessions. The chimpanzees' success rate and efficiency increased over time, whereas the amount of pulling in the absence of a partner decreased, demonstrating the animals had learned they needed a partner to succeed.","Similarly, extraneous pulling, i.e., pulls that did not lead to success, dropped significantly from the acquisition to the proficiency phase. The chimpanzees succeeded with significantly fewer pulls per success (e.g., higher efficiency) during the proficiency phase (Mixed Measures ANOVA: F 1,7 = 16.83, p = 0.005, Fig. For both of these measures there was no significant difference between dyadic and triadic tests (latency: F 1,7 = 0.11,p = 0.75; extra pulling: F 1,7 = 0.18,p = 0.68), demonstrating increased effectiveness of cooperation regardless of how many chimpanzees were needed for the task.","[4.0, 3.0, 4.0, 2.0, 3.0]",Biology,train,3.2,news,http://www.sciencedaily.com/releases/2014/06/140612085345.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/scitranslmed.aah6571,Biology_462,"The normal half-life of CO in humans after poisoning (the time it takes for half of the CO to be eliminated from the body) is 320 minutes, and even with 100-percent oxygen therapy, that time is 74 minutes.",This suggests that Ngb-H64Q-CCC will be a much more effective treatment for CO poisoning than is oxygen therapy in humans.,"When tested in a mouse model of non-lethal CO poisoning, they found that Ngb H64Q was significantly better at removing CO from hemoglobin than 100-percent oxygen treatment. The normal half-life of CO in humans after poisoning (the time it takes for half of the CO to be eliminated from the body) is 320 minutes, and even with 100-percent oxygen therapy, that time is 74 minutes. With the antidote therapy, the CO half-life was reduced to only 23 seconds.","Note that CO elimination in mice under normoxia and 100% oxygen is more than 20 times faster than CO elimination in humans, whereas the removal rates with exposure to Ngb-H64Q-CCC differ only by threefold between mouse and human RBCs (Fig. This suggests that Ngb-H64Q-CCC will be a much more effective treatment for CO poisoning than is oxygen therapy in humans. P = 0.0006 for MAP for time > 0, from mixedeffect model with unstructured covariance.","[5.0, 3.0, 2.0, 1.0, 3.0]",Biology,train,2.0,news,http://www.futurity.org/carbon-monoxide-poisoning-1312712/
10.1007/s11104-017-3408-5,Biology_464,Smaller diameter roots took up more water (per unit surface area) than bigger roots.,"Conclusions Our results highlight the need for continued exploration of root-trait specific water uptake rates in situ, and impacts of roots on soil hydraulic properties -both critical components for mechanistic modeling of root function.","A team overcame that problem. Smaller diameter roots took up more water (per unit surface area) than bigger roots. The Impact

Root water uptake can be linked to characteristic root traits, such as diameter or age.","Analysis based on rootfree bulk soil hydraulic properties indicated substantial redistribution of water via saturated/unsaturated flow and capillary wicking across the layers -suggesting water uptake dynamics following an infiltration event may be more complex than approximated by common soil hydraulic or root surface area modeling approaches. Conclusions Our results highlight the need for continued exploration of root-trait specific water uptake rates in situ, and impacts of roots on soil hydraulic properties -both critical components for mechanistic modeling of root function. The key advantage of NR is its sensitivity to lighter elements such as hydrogen and its stable isotope deuterium, which are particularly useful for investigation of the root water (H 2 O) uptake and transport through plants.","[3.0, 3.0, 1.0, 4.0, 3.0]",Biology,train,2.8,news,http://ct.moreover.com/?a=38670235769&p=1pl&v=1&x=_1QfkgHYs8fSKYS69MF28w
10.1073/pnas.1515733112,Biology_466,"Wallace and colleagues showed that in the mice, relatively mild mutations in mitochondrial genes, located in either mitochondrial DNA (mtDNA) or nuclear DNA, produced unique whole-body stress-response signatures, indicated by physiological and gene expression patterns.","We show that mitochondrial dysfunctions altered the hypothalamicpituitary-adrenal axis, sympathetic adrenal-medullary activation and catecholamine levels, the inflammatory cytokine IL-6, circulating metabolites, and hippocampal gene expression responses to stress.","aEURoeThis has profound implications for the hereditary basis of neuropsychiatric diseases and for the role of stress in human health.aEUR

Wallace and colleagues published their study ahead of print on Nov. 16 in Proceedings of the National Academy of Sciences. Wallace and colleagues showed that in the mice, relatively mild mutations in mitochondrial genes, located in either mitochondrial DNA (mtDNA) or nuclear DNA, produced unique whole-body stress-response signatures, indicated by physiological and gene expression patterns. These differential responses to stress due to mitochondrial variation provide a physiological explanation for a 2012 observation by WallaceaEUR(tm)s laboratory team.","This work shows that mitochondria can regulate complex whole-body physiological responses, impacting stress perception at the cellular and organismal levels. We show that mitochondrial dysfunctions altered the hypothalamicpituitary-adrenal axis, sympathetic adrenal-medullary activation and catecholamine levels, the inflammatory cytokine IL-6, circulating metabolites, and hippocampal gene expression responses to stress. Each mitochondrial defect generated a distinct whole-body stressresponse signature.","[1.0, 5.0, 4.0, 4.0]",Biology,train,5.0,news,http://healthmedicinet.com/news/mitochondria-affect-stress-responses/
10.1093/nar/gky1143,Biology_467,The researchers have discovered that the DNA gyrase focuses its twist-relaxation activities just in front of the point at which DNA is being replicated in a cell.,"Therefore, we suggest that the acute topological problem introduced by replication is primarily dealt with by gyrase enzymes performing processive catalysis to remove (+) supercoils ahead of replication, possibly at a higher rate than 1 supercoil/s, and we speculate that when gyrase fails to remove sufficient (+) supercoiling, replisome rotation is induced forming a substrate for topo IV behind the fork.","The researchers have discovered that the DNA gyrase focuses its twist-relaxation activities just in front of the point at which DNA is being replicated in a cell. We have now shown that several tens of DNA gyrase molecules actively bind to a zone directly in front of the replication machinery and relax the DNA nano-twists faster than the replication machinery itself moves along the DNA. Leake said, ""Now that we know how DNA gyrase really performs its role inside living bacteria, we can assist in the design of new types of drugs that can stop DNA gyrase from working, which will allow drugs to be more targeted and ultimately kill dangerous bacterial infections in humans.","In contrast, gyrase can remove (+) supercoils processively in vitro , consistent with our observations that its dwell time significantly increases close to the replisome. Therefore, we suggest that the acute topological problem introduced by replication is primarily dealt with by gyrase enzymes performing processive catalysis to remove (+) supercoils ahead of replication, possibly at a higher rate than 1 supercoil/s, and we speculate that when gyrase fails to remove sufficient (+) supercoiling, replisome rotation is induced forming a substrate for topo IV behind the fork. Our data suggest that local supercoiling may strongly influence gyrase off-rate, as we find with replication proximal gyrase remaining immobile for >8 s. Since the fork progresses at a rate of up to 1000 bp/s this would require initially binding ∼10 kb ahead of the fork to avoid collisions rather than directly ahead of it.","[3.0, 2.0, 4.0, 2.0, 4.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=37814376637&p=1pl&v=1&x=hRkLgt4tsp9_jPmw9ppvPA
10.1038/s41586-018-0189-9,Biology_468,"Our trees in Europe are not more tolerant than those in North America - their fungi are just suffering more.""","We conclude that environmental and host factors explain most of the variation in ectomycorrhizal diversity, that the environmental thresholds used as major ecosystem assessment tools need adjustment and that the importance of belowground specificity and plasticity has previously been underappreciated.","For example, current European nitrogen limits may need to be cut by half. Our trees in Europe are not more tolerant than those in North America - their fungi are just suffering more."" The team found that the characteristics of the tree (species and nutrient status) and the local environmental conditions (atmospheric pollution and soil variables) were the most important predictors of which species of mycorrhizal fungi would be present and their abundances.","We quantify host specificity and reveal plasticity in functional traits involved in soil foraging across gradients. We conclude that environmental and host factors explain most of the variation in ectomycorrhizal diversity, that the environmental thresholds used as major ecosystem assessment tools need adjustment and that the importance of belowground specificity and plasticity has previously been underappreciated. However, determinants of ectomycorrhizal diversity at local scales are not necessarily their primary drivers at larger scales 17 , and ectomycorrhizal communities are often dominated by hardly culturable and non-fruiting or inconspicuously fruiting fungi 18 .","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34239000953&p=1pl&v=1&x=7X_br_IO6XinOptP8AMd6w
10.1038/s41593-018-0083-7,Biology_469,"When proliferation of microglia was blocked, the mice failed to regain full muscle function, revealing how important microglia are for cleaning up clumps of misfolded proteins.","l, Representative cryosection of lumbar SC from 1 of 3 rNLS8 mice during peak microgliosis shows that the microglia are negative for CD44, a marker of peripheral myeloid cells.","Conversely, TDP-43 was not fully cleared in mice with no microglia. When proliferation of microglia was blocked, the mice failed to regain full muscle function, revealing how important microglia are for cleaning up clumps of misfolded proteins. ""The way reactive microglia protect neurons points us towards new ideas for ALS therapies,"" Spiller said.","g-k, Depleting peripheral myeloid cells had no effect on microgliosis. l, Representative cryosection of lumbar SC from 1 of 3 rNLS8 mice during peak microgliosis shows that the microglia are negative for CD44, a marker of peripheral myeloid cells. The microglial response pattern was unchanged in chimeric rNLS8 mice, with little microglia activation during disease and a sharp increase during recovery.","[3.0, 2.0, 3.0, 2.0, 2.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=33356797202&p=1pl&v=1&x=vURP2DTkpjl0RbCrbIUpcA
10.1111/gcb.13276,Biology_47,"""In our study, we observed a widely variable bleaching and mortality response among corals,"" Marcelino says.","The bleaching response of all taxa surveyed in a site was averaged to calculate the coral assemblage bleaching response (site-BRI or SBRI k , Eqn 11, average 33.76 AE 1.33 over 316 sites), which has been used to compare across sites and identify particular extrinsic factors affecting bleaching response (e.g., water flow, thermal history, acute thermal stress, and temperature variability; .","Rainforests of the sea

The index provides a valuable new tool to conservationists and park managers committed to preserving coral reefs and scientists interested in learning more about the hundreds of reef-building corals. ""In our study, we observed a widely variable bleaching and mortality response among corals,"" Marcelino says. ""Now, with the index, we have a platform we can use to better understand bleaching mechanisms, both intrinsic and environmental.","Comparing BRI j to the conclusions of for the 181 species found in both datasets, there is a significant positive correlation (logistic regression, r 2 = 0.03, P < 0.02) indicating congruence between BRI j and an independent assessment. The bleaching response of all taxa surveyed in a site was averaged to calculate the coral assemblage bleaching response (site-BRI or SBRI k , Eqn 11, average 33.76 AE 1.33 over 316 sites), which has been used to compare across sites and identify particular extrinsic factors affecting bleaching response (e.g., water flow, thermal history, acute thermal stress, and temperature variability; . If SBRI k truly reflects assemblage bleaching response at a site, it should account for thermalstress intensity and thermal-stress history of that assemblage.","[4.0, 2.0, 3.0, 2.0]",Biology,train,2.75,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1038/s41467-018-07396-3,Biology_470,"This study reveals how that 2D property is also graphene's Achilles' heel, by making it so vulnerable to surface contamination, and underscores how important high purity graphite is for the production of more pure graphene.","This leads to capacitance values much lower than the theoretical capacitance of graphene (550 F/g) 23 , with values of 409 F/g being the highest reported to date 24 .","""This level of inconsistency may have stymied the emergence of major industry applications for graphene-based systems. This study reveals how that 2D property is also graphene's Achilles' heel, by making it so vulnerable to surface contamination, and underscores how important high purity graphite is for the production of more pure graphene. When tested, the device's capacity to hold electrical charge was massive.","Moreover, this also indicates the possibility that the as-exfoliated graphene layers can each have different properties, again highlighting the importance of pure 2D materials. This leads to capacitance values much lower than the theoretical capacitance of graphene (550 F/g) 23 , with values of 409 F/g being the highest reported to date 24 . This calls for a broad effort to identify the types and extent of impurities present and the best way to deal with them to achieve the maximum potential of the broad family of 2D materials.","[4.0, 1.0, 3.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=37834220284&p=1pl&v=1&x=7wGw_IKaxrolJNG-m5BcSw
10.1016/j.cell.2013.09.057,Biology_471,The Type 2 PIP kinases are the backup rescue system to p53.,"The expression of either PIP4K2B or PIP4K2C is not significantly different across the subgroups of breast carcinomas with different ploidy status of TP53 (one-way ANOVA, p > 0.05).","If p53 is mutated or gone, then the cell keeps on growing at a very high rate,"" he says. The Type 2 PIP kinases are the backup rescue system to p53. But they only reduce ROS enough to keep the cells from dying.","TP53 mRNA expression is as expected progressively higher across the different subgroups of breast carcinomas with TP53 ploidy status ranging from n = 0 to n R 3 (one-way ANOVA, p = 4.3 3 10 À6 ), whereas PIP4K2A expression is only significantly higher in the subgroup of breast carcinomas with homozygous deletion of TP53 (one-way ANOVA, p = 0.009). The expression of either PIP4K2B or PIP4K2C is not significantly different across the subgroups of breast carcinomas with different ploidy status of TP53 (one-way ANOVA, p > 0.05). were identified that had relatively focal amplification of PIP4K2B without amplification of ERBB2 ( Figure 1A ).","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.sciencedaily.com/releases/2013/11/131107132827.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/scitranslmed.aan1230,Biology_472,"Tests in separate mouse models of liver injury demonstrated that liver cells started to express a senescence-associated gene signature within just 24 hours of paracetamol-induced liver injury, and this led to hepatocyte growth arrest.","In the mouse, this relationship was reversed upon inhibition of TGFR1, restoring a proportional regenerative response to liver injury, mimicking genetic deletion of p21.","""... worsening acute liver injury in humans results in a proportional expression of senescent markers by hepatocytes, associated with a reduced capacity for liver regeneration,"" the authors write. Tests in separate mouse models of liver injury demonstrated that liver cells started to express a senescence-associated gene signature within just 24 hours of paracetamol-induced liver injury, and this led to hepatocyte growth arrest. Further analyses showed that senescence was orchestrated by macrophage-produced TGFss, which was central to a signaling pathway that triggered senescence to spread between hepatocytes, starting at the site of injury and necrosis.","Therefore, severe liver injury in the mouse recapitulates the negative correlation between injury and regeneration observed in severe human disease (Fig. In the mouse, this relationship was reversed upon inhibition of TGFR1, restoring a proportional regenerative response to liver injury, mimicking genetic deletion of p21. Here, jaundice was once again improved and was associated with an inhibition of hepatocellular senescence (Fig.","[3.0, 5.0, 2.0, 2.0, 3.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34831954017&p=1pl&v=1&x=Soqa-eg-Jv9bMZT5LNf8zA
10.1038/ncomms12257,Biology_473,"""Regardless of the specific mechanism(s) for crater removal, our result requires that large crater obliteration was active well after the late heavy bombardment era, or about 4 billion years ago.","1a) and high crater depth-to-diameter ratios 17 , argue against relaxation of an ice-rich shell as the primary cause for the lack of large craters.","""It is as though Ceres cures its own large impact scars and regenerates new surfaces, over and over,"" Dr. Marchi said in a statement. ""Regardless of the specific mechanism(s) for crater removal, our result requires that large crater obliteration was active well after the late heavy bombardment era, or about 4 billion years ago. This conclusion reveals that Ceres' cratering record is inextricably linked to its peculiar composition and internal evolution.""","However, Ceres' significant topography range ( À 7.3 km, þ 9.5 km) with respect to the 482 Â 482 Â 446 km reference ellipsoid 16 , locally high crater spatial densities (Fig. 1a) and high crater depth-to-diameter ratios 17 , argue against relaxation of an ice-rich shell as the primary cause for the lack of large craters. Ceres collisional evolution.","[3.0, 2.0, 2.0]",Biology,train,2.333333333333333,news,http://www.redorbit.com/news/space/1113415206/craters-on-ceres-072716/
10.1016/j.cell.2015.01.040,Biology_474,"As expected, numerous genes inhibited late stages infection, but one stood out: SERPINE1, the gene that codes for PAI-1.","Experiments probing which stage of the viral life cycle was affected by PAI-1 showed no effects on early stages, replication, or egress ( Figures S3A-S3E ).","After seeing evidence of a new role for PAI-1, the researchers found that human and mouse cells unable to properly produce it appeared more vulnerable to infection by influenza A. As expected, numerous genes inhibited late stages infection, but one stood out: SERPINE1, the gene that codes for PAI-1. Subsequent experiments confirmed PAI-1 did indeed prevent the cutting of the fusion protein, known as hemagglutinin, and that high levels of PAI-1 prevented the virus from producing particles capable of spreading the infection.","In both A549 cells and HAEC, human parainfluenzavirus 3 (HPIV3) was unaffected by either of these treatments, showing that the effect was selective for IAV and not due to cytotoxicity (Figures S2H and S2I) . Experiments probing which stage of the viral life cycle was affected by PAI-1 showed no effects on early stages, replication, or egress ( Figures S3A-S3E ). PAI-1 inhibits protease function by forming a covalent, SDS-stable bond with the target protease, detectable in gel shift assays.","[4.0, 3.0, 2.0, 2.0]",Biology,train,2.75,news,http://www.sciencedaily.com/releases/2015/02/150212131651.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1126/scitranslmed.aah5645,Biology_476,"When used to treat the marrow in zebrafish and mouse models of DBA, the animals made erythroid progenitor cells that in turn made red blood cells, reversing or stabilizing anemia.",Identifying therapeutics for DBA requires circumventing the paucity of primary patient blood stem and progenitor cells.,"Because of its especially strong effect, SMER28 was put through additional testing. When used to treat the marrow in zebrafish and mouse models of DBA, the animals made erythroid progenitor cells that in turn made red blood cells, reversing or stabilizing anemia. The same was true in cells from DBA patients transplanted into mice.","Identifying therapeutics for DBA requires circumventing the paucity of primary patient blood stem and progenitor cells. Reprogrammed DBA progenitors recapitulate defects in erythroid differentiation, which were rescued by gene complementation. Unbiased chemical screens identified SMER28, a small-molecule inducer of autophagy, which enhanced erythropoiesis in a range of in vitro and in vivo models of DBA.","[4.0, 3.0, 2.0, 2.0]",Biology,train,2.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/dTVunQwrgGw/
10.1016/j.neuron.2015.11.036,Biology_479,"By examining the brains of these mice, the researchers observed a substantial decrease in inhibitory CA2 neurons, as compared to a control group of normal, healthy mice-a change remarkably similar to that previously observed in postmortem examinations of people with schizophrenia.","In fact, rescue of vasopressin 1b receptor expression specifically in area of CA2 in the hippocampus restored socially motivated attack responses in vasopressin 1b receptor knockout mice .","""Smaller and less well-defined than other parts of the hippocampus, CA2 was like a small island that was depicted on old maps but remained unexplored,"" explained Vivien Chevaleyre, PhD, group leader in neuroscience at the Universite Paris Descartes and a lead author of the paper. By examining the brains of these mice, the researchers observed a substantial decrease in inhibitory CA2 neurons, as compared to a control group of normal, healthy mice-a change remarkably similar to that previously observed in postmortem examinations of people with schizophrenia. Moreover, the team discovered that the modified mice had a significantly reduced capacity for social memory compared with the controls.","While there are multiple ways in which long-range connections can be disrupted, we speculate that the significant changes we see in CA2 PN output may potentially play a role in altering the long-range communication between the hippocampus and numerous other brain regions in the Df(16)A +/À mice. In fact, rescue of vasopressin 1b receptor expression specifically in area of CA2 in the hippocampus restored socially motivated attack responses in vasopressin 1b receptor knockout mice . Thus, it seems that mice with compromised CA2 function are unable to appropriately assess social situations.","[1.0, 3.0, 2.0, 4.0]",Biology,train,2.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/_hvl4_gYZ0U/
10.1210/en.2015-2036,Biology_48,"The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis.","We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) .","The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis. The finding builds upon several previous studies suggesting that low levels of vitamin D not only increase a person's risk of developing breast cancer, but are also correlated with more-aggressive tumors and worse prognoses. Although the research was conducted primarily in mice and on mouse cells, the researchers found in a study of 34 breast cancer patients that levels of circulating vitamin D were inversely correlated with the expression levels of ID1 protein in their tumors, and they confirmed that a vitamin D metabolite directly controls the expression of the ID1 gene in a human breast cancer cell line.","This 'hit' was of particular interest because of the role of Id1 in BCa progression and most intriguing because calcitriol was found to induce, rather than repress, ID1 expression in a colon carcinoma cell line . We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) . To test whether the regulation of Id1 by VDR is ligand dependent in BCa cells, we treated 168FARN cells with calcitriol and showed that this treatment represses the expression of Id1 ( Figure 3C ).","[3.0, 3.0, 1.0]",Biology,train,2.333333333333333,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.1038/ncomms3384,Biology_480,"""The study suggests that inhibiting FXR in the intestine might be a potential target for anti-obesity drugs,"" said Gonzalez.","In summary, metagenomics and metabolomics revealed that inhibition of intestinal FXR signalling by tempol treatment was associated with decreased Lactobacillus and its BSH activity.","""Eventually, we hope that this can lead to a new line of therapeutics to treat obesity and diabetes."" ""The study suggests that inhibiting FXR in the intestine might be a potential target for anti-obesity drugs,"" said Gonzalez. advertisement

The researchers said that tempol may help treat type 2 diabetes symptoms.","Whether this is a major pathway mediating the effects of tempol and FXR on obesity, warrants further investigation. In summary, metagenomics and metabolomics revealed that inhibition of intestinal FXR signalling by tempol treatment was associated with decreased Lactobacillus and its BSH activity. The accumulation of T-b-MCA in the intestine was accompanied by inhibition of FXR.","[3.0, 3.0, 1.0, 3.0, 2.0]",Biology,train,2.4,news,http://www.sciencedaily.com/releases/2013/09/130924113452.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.neuron.2013.11.023,Biology_482,"""We can perhaps use this to benefit our efforts to recover a lost sense,"" said Lee.",These alterations may increase sound discrimination performance of neurons .,"""There is some level of interconnectedness of the senses in the brain that we are revealing here,"" Kanold said. ""We can perhaps use this to benefit our efforts to recover a lost sense,"" said Lee. ""By temporarily preventing vision, we may be able to engage the adult brain to change the circuit to better process sound.""","Our results show increased responsiveness and frequency selectivity of A1 neurons due to changes at TC synapses. These alterations may increase sound discrimination performance of neurons . In addition to increased responsiveness, changes in the temporal pattern and reliability of responses may also improve encoding of sound features .","[1.0, 2.0, 3.0, 1.0, 1.0]",Biology,train,1.6,news,http://www.healthcanal.com/ear-nose-throat/47357-a-short-stay-in-darkness-may-heal-hearing-woes.html
10.1038/nature12172,Biology_485,"In addition, this work demonstrates the power of single-cell RNA sequencing to reveal cellular diversity without using a genetic perturbation.","Moreover, splicing patterns demonstrate previously unobserved levels of heterogeneity between cells.","""This work was the realization of something that people had hoped to do for a very long time,"" said Shalek. In addition, this work demonstrates the power of single-cell RNA sequencing to reveal cellular diversity without using a genetic perturbation. The biological insights from this effort, enabled by the diverse expertise and resources of the Broad, represent a first step in fulfilling the promise of unbiased, single-cell approaches to uncover biology.","In particular, hundreds of key immune genes are bimodally expressed across cells, surprisingly even for genes that are very highly expressed at the population average. Moreover, splicing patterns demonstrate previously unobserved levels of heterogeneity between cells. Some of the observed bimodality can be attributed to closely related, yet distinct, known maturity states of BMDCs; other portions reflect differences in the usage of key regulatory circuits.","[4.0, 4.0, 2.0, 4.0, 1.0]",Biology,train,4.0,news,http://www.healthcanal.com/medical-breakthroughs/38932-surveying-cells-one-at-a-time.html
10.1038/s41598-018-28950-5,Biology_486,"The researchers said the next step in the research is to evaluate the same chemicals in a more complex in vitrosystem that incorporates additional supporting cell types, adding that the study could also be used to optimize three-dimensional brain-on-a-chip devices that Lab researchers are currently developing.","Furthermore, neuronal cultures, in contrast to brain slices cultured on MEAs, are more readily adapted to human-relevant systems by utilizing either human primary or stem-cell derived neurons.","Researchers said the differences in neural activity demonstrated between the in vivoneural recordings and in vitrochip-based devices could be explained by the lack of supporting brain cell types cultured on the chip, varied metabolism, cell ratios, differences in GABA levels in the brain, and effects involving parts of the brain other than the prefrontal cortex, where the multi-electrode devices were implanted in the rodents. The researchers said the next step in the research is to evaluate the same chemicals in a more complex in vitrosystem that incorporates additional supporting cell types, adding that the study could also be used to optimize three-dimensional brain-on-a-chip devices that Lab researchers are currently developing. ""As we increase the complexity of these devices and make advances in engineering and biology, we can test the same drugs and make those comparisons,"" Enright said.","Fully validated systems hold promise for evaluating new drugs, characterizing toxicants, and aiding in the elucidation of disease mechanisms. Furthermore, neuronal cultures, in contrast to brain slices cultured on MEAs, are more readily adapted to human-relevant systems by utilizing either human primary or stem-cell derived neurons. As such, a direct comparison of dissociated neuronal cultures to whole brain provides important and necessary information to frame the relevance of in vitro data sets.","[2.0, 3.0, 2.0, 2.0, 1.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34562613600&p=1pl&v=1&x=ysG9ceP84op0bQq4fgh9KQ
10.1016/j.ebiom.2017.03.046,Biology_487,"However, when biological age is considered with adjustment for chronological age, overall richness decreases, while certain bacterial taxa associated with unhealthy aging thrive.","Moreover, data also suggest that most of the biological age predictors we have discussed have little or no interaction with each other.","With advancing chronological age, the gut microbiota becomes more diverse. However, when biological age is considered with adjustment for chronological age, overall richness decreases, while certain bacterial taxa associated with unhealthy aging thrive. Thus, as biological age increases, the homeostatic relationship between the gut microbiota and the host deteriorates, while gut dysbiosis increases.","Additional longitudinal data are necessary to further confirm the causal nature. Moreover, data also suggest that most of the biological age predictors we have discussed have little or no interaction with each other. Thus, effects are independent of each other and may therefore be describing different parts of the aging process.","[3.0, 3.0, 1.0, 2.0, 2.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=34648061343&p=1pl&v=1&x=HHTggJy9BxPjx7_HH42vyA
10.1098/rspb.2013.1680,Biology_489,The team was able to show that an active ingredient in the peppers stimulates specific RA1 fibres in the lips and tongue.,"Furthermore, participants anecdotally described a qualitative difference between the tingling induced by the Szhechuan pepper and the other control conditions.","The study, which is published in the journal Proceedings of the Royal Society B, helps shed light on the complex interactions between the senses of taste and touch, and could lead to a greater understanding of the causes of the tingling sensations experienced by many chronic pain patients. The team was able to show that an active ingredient in the peppers stimulates specific RA1 fibres in the lips and tongue. Dr Hagura said: ""What we found was that a unique active ingredient in the pepper, called sanshool, activates these fibres, sending a highly specific signal to the brain.","By contrast, for the Szechuan pepper condition, 12 out of 12 participants agreed to the description 'tingle', regardless of the condition order. Furthermore, participants anecdotally described a qualitative difference between the tingling induced by the Szhechuan pepper and the other control conditions. Therefore, only the Szechuan pepper reliably induced the sensation having a specific tingling quality, consistent with involvement of a specific class of afferents.","[4.0, 2.0, 3.0, 3.0, 4.0]",Biology,train,3.2,news,http://www.sciencedaily.com/releases/2013/09/130910205326.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/nn.3728,Biology_490,"""FTY720/fingolimod may be a useful adjuvant therapy to help stop aversive memories such as in post-traumatic stress disorder and other anxiety disorders,"" Spiegel said.","Altogether, these data indicate that FTY720 protected the SCID mice from deficits in expression of extinction in the contextual fear model.","""It will be important in the future to determine whether this prodrug can reduce loss of cognitive functions and can erase adverse memories,"" she said. ""FTY720/fingolimod may be a useful adjuvant therapy to help stop aversive memories such as in post-traumatic stress disorder and other anxiety disorders,"" Spiegel said. We are still working to fully understand the molecular underpinnings of the drug and its link to memory,"" she said.","7d-f) , nor tonedependent fear conditioning that is hippocampus independent, nor did it affect extinction of response to the tone conditioned stimulus (Supplementary Fig. Altogether, these data indicate that FTY720 protected the SCID mice from deficits in expression of extinction in the contextual fear model. This aspect of learning is important for the organism to reduce fear-related behavior in response to a stimulus that no longer predicts an aversive event.","[1.0, 4.0, 3.0]",Biology,train,2.6666666666666665,news,http://www.healthcanal.com/brain-nerves/51296-basic-research-shows-that-drug-used-to-treat-multiple-sclerosis-may-have-beneficial-effects-on-memory.html
10.1038/ni.2758,Biology_491,Their data showed that HCV could induce liver cells to target the activities of the IFNL3 gene with two microRNAs.,The IFNL3-T 3′ UTR conferred 30-40% lower luciferase activity than did the IFNL3-G 3′ UTR (Fig.,"Individuals who carry the T (for thymidine) variant have an unfavorable outcome in fighting HCV, while those who carry the G (for guanosine) variant have a favorable outcome. Their data showed that HCV could induce liver cells to target the activities of the IFNL3 gene with two microRNAs. These two particular microRNAs are generally turned off in liver cells, until HCV coerces them to act on its behalf.",1a and Supplementary Fig. The IFNL3-T 3′ UTR conferred 30-40% lower luciferase activity than did the IFNL3-G 3′ UTR (Fig. Analysis of the firefly luciferase-encoding mRNA that remained in HepG2 cells after treatment with actinomycin D revealed that mRNA bearing the IFNL3-T 3′ UTR decayed twice as fast as that bearing the IFNL3-G 3′ UTR (Fig.,"[3.0, 2.0, 3.0, 2.0]",Biology,train,2.5,news,http://www.sciencedaily.com/releases/2014/02/140210095412.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cub.2017.12.015,Biology_492,"""It means they can learn associations about who is more defensive and who isn't, and if we can prevent that, they'll never learn and can be swatted away way more effectively.""","This choice is not random; most mosquitoes specialize in one or a few vertebrate host species, and some individuals in a host population are preferred over others.","Without the help of dopamine, the neurons fired less frequently with the scents, which suggests that the bugs would be less able to learn to avoid odors associated with swats. ""It means they can learn associations about who is more defensive and who isn't, and if we can prevent that, they'll never learn and can be swatted away way more effectively."" As Riffel tells Klein, the knowledge that mosquito learning relies on dopamine could lead to genetic modifications or insecticides that trigger the memory of avoidance, forcing the insects to avoid people.","This choice is not random; most mosquitoes specialize in one or a few vertebrate host species, and some individuals in a host population are preferred over others. Here, we show that olfactory learning may contribute to Aedes aegypti mosquito biting preferences and host shifts. Using pharmacological interventions, RNAi, and CRISPR gene editing, we found that modification of the dopamine-1 receptor suppressed their learning abilities.","[3.0, 2.0, 3.0, 2.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=33205869755&p=1pl&v=1&x=n3n5bgAKOEb6WUEzUYrPtQ
10.1016/j.neuron.2013.09.021,Biology_493,"""So what we think is happening is knocking down FoxP2 makes the male incapable of reducing song variability in the presence of a female,"" Murugan said.","Therefore, reducing FoxP2 levels in Area X abolishes context-dependent changes in both LMAN singing-related activity and song variability.","The birds with suppressed FoxP2 genes also had insensitivities to dopamine, which normally should produce reward-seeking behaviors, but in the mutant subjects had no effect. ""So what we think is happening is knocking down FoxP2 makes the male incapable of reducing song variability in the presence of a female,"" Murugan said. It arises primarily from the mutation's impairment on motor control, as children with DVD have repeated trouble forming consonants and vowel sounds.","Finally, both the mean firing rates and levels of bursting activity of LMAN neurons recorded in the directed state were significantly higher in the LV-ShFoxP2 birds (Figures 6D and 6E ; p = 0.006 and p = 0.013, respectively). Therefore, reducing FoxP2 levels in Area X abolishes context-dependent changes in both LMAN singing-related activity and song variability. Notably, the AFP affects syllable variability through the synapses that LMAN axons make on RA neurons (Ö lveczky et al., 2005) , and the variability of action potential timing in RA neurons can account for a significant fraction of acoustic variation in the bird's song .","[5.0, 5.0, 4.0, 4.0, 4.0]",Biology,train,4.4,news,http://www.medicaldaily.com/genetic-foxp2-defect-may-cause-speech-disorders-independent-learning-disabilities-263436
10.1126/sciadv.1501344,Biology_494,"""We found that this specific extreme ridge pattern associated with the ongoing California drought has increased in recent decades,"" Swain says.","Such large heterogeneity in the atmospheric circulation patterns that lead to extremely low seasonal-scale precipitation strongly reinforces the importance of separately considering each pattern when assessing long-term trends, particularly for the case of drought.","The new study provides a more direct answer. ""We found that this specific extreme ridge pattern associated with the ongoing California drought has increased in recent decades,"" Swain says. ""We're seeing an increase in certain atmospheric patterns that have historically resulted in extremely dry conditions, and yet that's apparently not occurring at the expense of patterns that have historically been associated with extremely wet patterns,"" Swain says.","These considerations become especially relevant when attempting to infer the likelihood of changes in meteorological extremes from changes in the mean state. Such large heterogeneity in the atmospheric circulation patterns that lead to extremely low seasonal-scale precipitation strongly reinforces the importance of separately considering each pattern when assessing long-term trends, particularly for the case of drought. The simulated response of California's long-term mean annual precipitation to strongly elevated (that is, ""future"") greenhouse forcing has Wet October-May","[1.0, 2.0, 3.0, 3.0, 2.0]",Biology,train,2.2,news,http://www.futurity.org/california-drought-1131262-2/
10.1016/j.cell.2014.12.038,Biology_495,"The researchers then identified more than 5,000 genes spanning dozens of species that had significant copy number variations across microbiomes.","Notably though, we did not detect significantly more variation in clusters for which more reference genomes were available.","Using a novel computational and statistical analysis, Borenstein and his team were able to accurately map each sequence to its species of origin and to estimate the copy number of tens of thousands of genes in scores of gut-dwelling species in the gut microbiomes of more than a hundred individuals. The researchers then identified more than 5,000 genes spanning dozens of species that had significant copy number variations across microbiomes. In fact, they found such variable genes in every species they analyzed with some species showing variation in almost a quarter of their genes.","First, our analysis is limited to the detection of variation in gut species for which at least one fully sequenced genome is available, and future studies may benefit from additional genomes. Notably though, we did not detect significantly more variation in clusters for which more reference genomes were available. In addition, our pipeline was designed to detect gene losses or amplifications but cannot identify gain of genes that are not present in any of the reference genomes included in the genome cluster.","[1.0, 2.0, 2.0]",Biology,train,1.6666666666666667,news,http://www.sciencedaily.com/releases/2015/01/150129125505.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1073/pnas.1409328111,Biology_496,Knowledge about both the maternal age effect and the bottleneck size is useful in family planning.,"Notably, we found a positive association between the number of heteroplasmies in a child and maternal age at fertilization, likely attributable to oocyte aging.","""Knowing the size of the bottleneck allows us to predict, within a range, the percentage of disease-carrying molecules that will be passed on to the child."" Knowledge about both the maternal age effect and the bottleneck size is useful in family planning. ""We have some predictive power now and can assist genetic counselors in advising couples about the chances of mitochondrial diseases being passed to the next generation,"" Makova said.","mutations per site per year, an order of magnitude higher than for nuclear DNA. Notably, we found a positive association between the number of heteroplasmies in a child and maternal age at fertilization, likely attributable to oocyte aging. Our results can be used to predict the transmission of disease-causing mtDNA variants and illuminate evolutionary dynamics of the mitochondrial genome.","[5.0, 3.0, 4.0, 4.0, 2.0]",Biology,train,3.6,news,http://www.sciencedaily.com/releases/2014/10/141013152816.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1002/dneu.22629,Biology_497,"Thus when placodes were transplanted to the vicinity of the heart, the outgrowing nerve cells followed the course of the vagus nerve, which originates deep in the hindbrain and is responsible for controlling the heartbeat.",7A) identified afferents of the inner ear projecting with the vagus nerve (Fig.,"They found that the ectopically located neurons grow along existing nerve tracts nearby. Thus when placodes were transplanted to the vicinity of the heart, the outgrowing nerve cells followed the course of the vagus nerve, which originates deep in the hindbrain and is responsible for controlling the heartbeat. When the placode was placed at a level midway along the dorsolateral flank, it gave rise to a complete inner ear.","These data suggest that afferents of the inner ear are capable of projecting with peripheral nerves but do so as undirected growth along existing peripheral nerves. 7A) identified afferents of the inner ear projecting with the vagus nerve (Fig. Furthermore, placement of dye into the vagus nerve (Fig.","[4.0, 1.0, 3.0, 2.0, 2.0]",Biology,train,2.4,news,http://ct.moreover.com/?a=34644118544&p=1pl&v=1&x=unNNhQH0NvlgNNMwuUADgA
10.1038/s41586-019-1291-3,Biology_498,"""We hope this study provides a useful first step in understanding the microbiome contribution to drug metabolism,"" co-lead author Michael Zimmermann said in the news release.","This analysis correctly identifies reported microorganismderived drug metabolites 10 (for example, metabolites of sulfasalazine, paliperidone and pantoprazole; Supplementary Table 5) .","The team found wide variations in the number of these genes in healthy people. ""We hope this study provides a useful first step in understanding the microbiome contribution to drug metabolism,"" co-lead author Michael Zimmermann said in the news release. ""We think these approaches could shed light on how the gut microbiome also modulates our response to non-drug compounds, such as dietary nutrients and environmental agents,"" Zimmermann said.","In addition, we included only compounds that significantly accumulated (fold change (expressed in log 2 ) ≥ 1, FDR-corrected P value ≤ 0.05), whereas their associated parent drug decreased upon bacterial incubation. This analysis correctly identifies reported microorganismderived drug metabolites 10 (for example, metabolites of sulfasalazine, paliperidone and pantoprazole; Supplementary Table 5) . We found 871 candidate drug metabolites that are specific to the presence of a given drug; these represent direct products of bacterial drug modifications or bacterial responses that are unique to a specific drug (blue bars in Fig.","[2.0, 3.0, 3.0]",Biology,train,2.6666666666666665,news,http://ct.moreover.com/?a=39377789963&p=1pl&v=1&x=YIPWMJ3-1blomtuO0R4AvA
10.1016/j.cell.2018.06.004,Biology_499,The normal function of the REST protein is to shut off genes that need to be active only in a very few cell types.,"Among these, 15 were high-confidence REST targets, and expression of 10 of the 15 was moderately (i.e., <2-fold; Table S4 ) reduced in the Rest +/DEx4 neocortex.","Deafness is genetically dominant in the LMG2 family, meaning that a child needs to inherit only one copy of the defective gene from a parent to have progressive hearing loss. The normal function of the REST protein is to shut off genes that need to be active only in a very few cell types. When Banfi's team deleted exon 4 of Rest in mice, inner ear hair cells died, and mice became deaf.","RNA-seq analysis of neocortices of E15.5 WT and Rest +/DEx4 mice revealed differential expression of 100 genes ( Figure 4B ). Among these, 15 were high-confidence REST targets, and expression of 10 of the 15 was moderately (i.e., <2-fold; Table S4 ) reduced in the Rest +/DEx4 neocortex. For high-confidence REST targets randomly selected from the cortical and utricular RNA-seq datasets, qRT-PCR analysis at additional time points demonstrated that expression in the Rest +/DEx4 neocortex was reduced at E16, but not P6 and P16","[3.0, 2.0, 3.0, 4.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=34419502557&p=1pl&v=1&x=ufamkTL0CRdeKcRvLWsq0Q
10.1002/emmm.201302567,Biology_5,The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.,SMN2 mis-splicing increased during late-stage disease.,"Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA. How much a patient is helped depends on the number of copies of the SMN2 gene they possess.","Systemic ASO injection elicited marked liver and heart pathologies, and resulted in decreased levels of circulating IGF1. SMN2 mis-splicing increased during late-stage disease. Our study also suggests that high SMN levels are not as critical in adults, and there is a broad therapeutic time window for treatment of adult-onset SMA.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1073/pnas.1504869112,Biology_50,"Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more.","The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests.","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Liana-tree competition can be far more intense than tree-tree competition (3), substantially reducing tree growth , fecundity , and survival . The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .","[3.0, 3.0, 2.0, 2.0]",Biology,train,2.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1038/nature14217,Biology_501,But this study found widespread differences in how genes are regulated (turned on and off) between the two chromosomes in a pair.,"Furthermore, if allelic imbalances of enhancer activities indeed contribute to allelically biased gene expression, we expect that chromatin states at enhancers will be concordant with the expression of their targets.","""Both of these studies provide important considerations for clinicians and researchers who are developing personalized medicines based on a patient's genomic information,"" said Bing Ren, PhD, professor of cellular and molecular medicine at UC San Diego, Ludwig Cancer Research member and senior author of both studies. But this study found widespread differences in how genes are regulated (turned on and off) between the two chromosomes in a pair. It turns out that we all have ""biases"" in our chromosomes.","8a ). Furthermore, if allelic imbalances of enhancer activities indeed contribute to allelically biased gene expression, we expect that chromatin states at enhancers will be concordant with the expression of their targets. Therefore, we generated additional H3K27ac ChIP-seq data sets with deeper coverage and longer sequencing reads (for better delineation of alleles) for 14 of the previously analysed tissue samples and an additional 6 samples from independent donors (Supplementary Table 7 ).","[2.0, 3.0, 3.0, 1.0, 3.0]",Biology,train,2.4,news,http://www.sciencedaily.com/releases/2015/02/150218072753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.celrep.2014.05.027,Biology_503,"The fact that these cells had remained healthy indicated that the transplants had been successful and that the transplanted cells had not been corrupted as some researchers had suggested they likely had been in other studies, said Dr. Isacson, lead author of the paper.","A general assessment of the integrity of the grafted TH-immunoreactive neurons in all patients revealed cells with a healthy appearance, including a robust cell soma and absence of signs of atrophy ( Figures 1A-1C , 1F-1H, 1K-1M, and 1P-1R).","""We have shown in this paper that the transplanted cells connect and live well and do all the required functions of nerve cells for a very long time,"" said Ole Isacson, MD (DR MED SCI), director of the Neuroregeneration Research Institute at McLean and a professor of neurology and neuroscience at Harvard Medical School. The fact that these cells had remained healthy indicated that the transplants had been successful and that the transplanted cells had not been corrupted as some researchers had suggested they likely had been in other studies, said Dr. Isacson, lead author of the paper. ""These findings are critically important for the rational development of stem cell-based dopamine neuronal replacement therapies for Parkinson's,"" the paper concluded.","Postmortem examinations demonstrated that grafted dopaminergic neurons survived for up to 14 years posttransplantation. A general assessment of the integrity of the grafted TH-immunoreactive neurons in all patients revealed cells with a healthy appearance, including a robust cell soma and absence of signs of atrophy ( Figures 1A-1C , 1F-1H, 1K-1M, and 1P-1R). In two independent patients at 4 years posttransplantation ( Figures 1A-1J ), an examination of DAT/TH immunostaining at low magnification (Figures 1A and 1F) showed dense DAT and TH expression in the reinnervated putamen and caudate in areas both near to and farther away from the graft.","[2.0, 3.0, 2.0, 3.0]",Biology,train,2.5,news,http://www.sciencedaily.com/releases/2014/06/140605141505.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41564-018-0276-6,Biology_504,"If the coal fire-fueled soils around Centralia, Pennsylvania, are any indication, organisms with smaller genomes and cells may do well in the future.","These results add evidence that supports selection for both smaller genomes and cells at higher temperatures, but also offer a key point of distinction.","If the coal fire-fueled soils around Centralia, Pennsylvania, are any indication, organisms with smaller genomes and cells may do well in the future. The research clearly shows that, for soil microbiomes, hot temperatures result in both smaller genomes on average and also smaller cell sizes, said Ashley Shade, MSU microbial biologist, and the study's lead author. This isn't the case of simply one microbe embracing an economical approach, either; the majority of populations living in the steaming ground have these same traits.","Surprisingly, it also suggests that microbial populations inhabiting complex environments, such as soils, may generally reflect similar overarching traits in genome size to those observed in laboratory studies. These results add evidence that supports selection for both smaller genomes and cells at higher temperatures, but also offer a key point of distinction. Although taxa that were enriched in hot soils characteristically had smaller genomes and cells, there is no evidence for contemporary genome streamlining in Centralia.","[3.0, 4.0, 3.0, 4.0]",Biology,train,3.5,news,http://ct.moreover.com/?a=37601068214&p=1pl&v=1&x=vr1rdpS21uAb7g2XAsLY7g
10.1038/s41588-018-0153-5,Biology_505,Unlocking the genomic sequence gives scientists unprecedented insights into the unique biology of the koala.,"At a continental scale, we show biogeographic barriers to gene flow associated with the Brisbane Valley and Clarence River, as identified by mtDNA studies , and find a barrier associated with the Hunter Valley, which was not previously known in koalas (Fig.","They have sequenced over 3.4 billion base pairs and more than 26,000 genes in the Koala genome - which makes it slightly larger than the human genome. Unlocking the genomic sequence gives scientists unprecedented insights into the unique biology of the koala. Professor Johnson said the uneven response of koala populations throughout their range was one of the major challenges facing broad scale management of the species.","We found evidence of low genetic diversity in southern koalas, consistent with a recent history of sequential translocations (Fig. At a continental scale, we show biogeographic barriers to gene flow associated with the Brisbane Valley and Clarence River, as identified by mtDNA studies , and find a barrier associated with the Hunter Valley, which was not previously known in koalas (Fig. Levels of inbreeding varied across regions (Fig.","[4.0, 2.0, 4.0, 4.0, 4.0]",Biology,train,3.6,news,http://ct.moreover.com/?a=34448439826&p=1pl&v=1&x=r-Spkb_Bgw9TuPKhig_SUw
10.1890/14-0169.1,Biology_506,"""Sometimes they can help invasive species spread in exactly the same way they help native species.""","The first is that corridors promote the initial spread of fire ants, in our case from their initial and limited distribution within the matrix where our experimental patches were created.","The findings, published in the journal Ecology, are particularly relevant to Florida, where invasive species like Cuban tree frogs, green iguanas and feral hogs are considered a serious ecological problem. ""Sometimes they can help invasive species spread in exactly the same way they help native species."" The researchers were initially surprised by their findings because they assumed that invasive species could easily invade a new area without the help of corridors to get around.","In our study system, there are two mechanisms by which corridors could increase population densities of fire ants. The first is that corridors promote the initial spread of fire ants, in our case from their initial and limited distribution within the matrix where our experimental patches were created. Given that the area of two patches connected by a corridor is approximately double the area of an unconnected patch, it was much more likely that connected patches would have been created in the location of an already existing polygyne colony.","[1.0, 3.0, 1.0, 2.0]",Biology,train,1.75,news,http://www.natureworldnews.com/articles/8435/20140807/invasive-species-may-spread-via-wildlife-corridors.htm
10.1016/j.cell.2014.03.027,Biology_508,The researchers found that the mice with a single mutated copy of PTEN were more tumor-prone than the mice with a deleted copy of PTEN.,We show that dimer PTEN is active toward its phosphoinositide substrate PIP3 and thereby inhibits the activation of the PI3K/ AKT signaling pathway.,"It turned out the answer was yes."" The researchers found that the mice with a single mutated copy of PTEN were more tumor-prone than the mice with a deleted copy of PTEN. They also discovered that the mutated protein that was produced by PTENC124S or PTENG129E was binding to and inhibiting the PTEN protein made from the normal copy of the PTEN gene.","Regulation of PTEN function occurs through various posttranslational modifications implicated in PTEN membrane recruitment, subcellular localization, or protein-protein interactions . We show that dimer PTEN is active toward its phosphoinositide substrate PIP3 and thereby inhibits the activation of the PI3K/ AKT signaling pathway. By cotransfecting differentially tagged PTEN variants we were able to reciprocally co-IP GFPPTEN and MycPTEN ( Figure 1A ).","[4.0, 2.0, 2.0]",Biology,train,2.6666666666666665,news,http://www.newswise.com/articles/surprising-new-insights-into-pten-tumor-suppressor-gene
10.1038/s41467-018-06087-3,Biology_509,Addition of low amounts of glucose into the environment produced a cooperative interaction between the host and guest protocells such that the two enzymes worked together to produce a spatially coupled chemical cascade.,Self-reconfiguration of host-guest protocells containing spatially separated GOx and HRP produced multi-enzyme vesicle-inproteinosome nested microstructures.,"The work opens new perspectives to develop synthetic soft materials endowed with life-like properties. Addition of low amounts of glucose into the environment produced a cooperative interaction between the host and guest protocells such that the two enzymes worked together to produce a spatially coupled chemical cascade. However, increasing the level of the glucose signal turned the guest protocells against their host which led to the pH-induced disassembly of the coacervate droplets and release of the resident proteinosomes.","For example, internalisation of the fatty acid vesicles within the proteinosomes resulted in a 1.7 to 2.6-fold accumulation of positively charged, low-molecular weight solutes (RITC-HRP, αdansyl-L-arginine or RITC-labelled Mb) compared with the external continuous phase (Fig. Self-reconfiguration of host-guest protocells containing spatially separated GOx and HRP produced multi-enzyme vesicle-inproteinosome nested microstructures. Whereas GOx was retained within the aqueous phase of the released proteinosomes, HRP was entrapped specifically within the guest vesicles (Fig.","[1.0, 2.0, 2.0, 2.0, 4.0]",Biology,train,2.2,news,http://ct.moreover.com/?a=37036174206&p=1pl&v=1&x=_dNiyKDpGEqqKRgeX_TcPQ
10.1126/science.1072290,Biology_510,But it wasn't just his wife who reacted this way.,"In cells transiently transfected with M50/p35 and M53/ p38, Ca-dependent PKCs were recruited to the NE (Fig.","It wasn't that surprising, she said. But it wasn't just his wife who reacted this way. Friends and colleagues told him the same thing, that he was ""kind of not there emotionally,"" Fallon recalls.","Among the kinases tested, only Ca-dependent PKCs were found to be redistributed to the NE by viral proteins (13) . In cells transiently transfected with M50/p35 and M53/ p38, Ca-dependent PKCs were recruited to the NE (Fig. In MCMV-infected cells, M50/p35 colocalized with M53/p38 and Ca-dependent PKC (Fig.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.businessinsider.com/psychopath-who-studies-psychopaths-2015-7
10.1038/ncomms15679,Biology_512,"Maybe they will interact differently with heat or electricity, for example.""",Feature selection in decision tree ensembles cannot differentiate between primary effects and effects caused by interactions between variables.,"They might also have useful properties that diamonds don't have. Maybe they will interact differently with heat or electricity, for example."" As Zurek explains, it means that ""if you try to indent a material with a sharp tip, a hole will not be made, or the hole will be very small.""","The steepest descent direction is the negative gradient of the loss function evaluated at the current model F m−1 , where the step length is chosen using line search. Feature selection in decision tree ensembles cannot differentiate between primary effects and effects caused by interactions between variables. Therefore, unlike regression coefficients, a direct comparison of captured effects is prohibited.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=40151614624&p=1pl&v=1&x=B7f4dNZWpH6DeMbmyaCo4A
10.1073/pnas.1402074111,Biology_513,Egypt becomes the 15th country to report a MERS case and the latest one outside the Arabian Peninsula.,"At concentrations ≥20 μg/mL, six of seven scFvFcs neutralized MERS-CoV completely (Fig.","He was reportedly being treated for pneumonia and was in stable condition at last report. Egypt becomes the 15th country to report a MERS case and the latest one outside the Arabian Peninsula. According to Saudi Arabia's Ministry of Health, five more people in the kingdom have died from MERS as of Sunday, April 27.","The other three scFvFcs, 1E9, M14D3, and 1F8, neutralized the virus with IC values of 3.21, 4.3, and 6.27 μg/mL, respectively (Table S1 ). At concentrations ≥20 μg/mL, six of seven scFvFcs neutralized MERS-CoV completely (Fig. Three IgG1 Abs also were tested for live virus neutralization; 3B11 had a lower IC value than 1F8 and 3A1 IgGs (Table S1 ).","[1.0, 1.0, 2.0, 1.0, 2.0]",Biology,train,1.4,news,http://www.redorbit.com/news/health/1113132613/mers-studies-disease-camels-egypt-042914/
10.1038/s41467-017-00174-7,Biology_514,But there are likely other genetic rearrangements that are occurring as a result of that radiation-induced DNA damage.,Supporting our WES data ( Fig.,"""Our research identified a specific rearrangement involving the NF2 gene that causes radiation-induced meningiomas. But there are likely other genetic rearrangements that are occurring as a result of that radiation-induced DNA damage. He adds: ""In addition, identifying the subset of childhood cancer patients who are at highest risk to develop meningioma is critical so that they could be followed closely for early detection and management.""","The inclusion of intron 11 introduces a premature stop codon that disrupts NF2 function through generation of a truncated protein (Supplementary Figs 3B, C). Supporting our WES data ( Fig. 1 core radiationinduced meningioma cohort), we found the mutation rate of NF2 was 3.5 times lower in RIMs, with only two mutations (focal NF2 mutations) identified in RIMs, but confirmed their common occurrence (7/30, 23%) in sporadic meningiomas (Fig.","[1.0, 4.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://healthmedicinet.com/news/brain-tumor-scientists-map-mutation-that-drives-tumors-in-childhood-cancer-survivors/
10.1098/rsif.2014.0409,Biology_515,"""In this case, the sentence length for black Americans is on one side of this point while that for whites is on the other.""","Recidivism by age is the only metric by which the non-contagious model roughly reproduces the same results as seen in the real data, though even here the shape of the curve appears markedly rounder than in the California data and lacks the characteristic demographic bulge.","Focusing on the potential effects of the sentence length opens a host of questions for future work, says James Moody, a sociologist at Duke University in Durham, North Carolina. ""In this case, the sentence length for black Americans is on one side of this point while that for whites is on the other."" The model's predictions were borne out almost exactly.","The probability of recidivism is essentially flat with respect to the length of the sentence under a noncontagious model; real data and the contagious model both show that longer sentences result in a decreased probability of recidivism. Recidivism by age is the only metric by which the non-contagious model roughly reproduces the same results as seen in the real data, though even here the shape of the curve appears markedly rounder than in the California data and lacks the characteristic demographic bulge. Based on the lack of correspondence between reality and recidivism data generated under a non-contagious model coupled with the close correspondence between reality and rsif.royalsocietypublishing.org J. R. Soc.","[1.0, 1.0, 2.0, 1.0, 1.0]",Biology,train,1.2,news,http://news.sciencemag.org/biology/2014/06/prison-contagious
10.1038/s41587-019-0095-1,Biology_516,"""We're able to fine-tune the strength of the lock just enough so that the guide RNA still works when it meets its correct match,"" says Kocak.","5c,d and Supplementary Fig.","But because the guide RNA would prefer to bind to DNA rather than itself, the correct combination of DNA is still able to break the lock. ""We're able to fine-tune the strength of the lock just enough so that the guide RNA still works when it meets its correct match,"" says Kocak. In the paper, Kocak and Gersbach show that this method can increase the accuracy of cuts made in human cells by an average of 50-fold across five different CRISPR systems derived from four different bacterial strains.","We observed that both AsCas12a and LbCas12a activity can be regulated by spacer secondary structure and that off-target activity can be reduced without altering on-target activity by tuning the strength of the secondary structure (Fig. 5c,d and Supplementary Fig. Truncated crRNAs did not consistently result in specificity increases for either AsCas12a or LbCas12a, indicating that this .","[3.0, 1.0, 1.0, 1.0]",Biology,train,1.5,news,https://www.futurity.org/crispr-tail-accuracy-2036202/
10.1038/s41467-018-03989-0,Biology_517,Remember that the next time illness lays you low.,"During the repeated mental simulation of a movement, the forward models could use the difference between the predicted and the desired outcome as the teaching signal in the updating process, thereby establishing a better and finer motor performance on subsequent overt execution.","By seeing a mental image of a healthier you, you're priming yourself to get on the road to improvement. Remember that the next time illness lays you low. Keep in mind that smart choices are often the ones given appropriate time to consider carefully.","The present study indicates that the motor improvement seen after the mental practice of movements might be due to the forward models running offline based on the efference copy alone during imagery. During the repeated mental simulation of a movement, the forward models could use the difference between the predicted and the desired outcome as the teaching signal in the updating process, thereby establishing a better and finer motor performance on subsequent overt execution. Motor imagery thus truly corresponds to the mind's internal simulation of action that can be used to improve further performance and induce neural plasticity.","[3.0, 1.0, 1.0]",Biology,train,1.6666666666666667,news,http://ct.moreover.com/?a=33950830721&p=1pl&v=1&x=6SzYDxFoMrWx1LMa__YQow
10.1038/nature09273,Biology_518,"Two aspects of the CTFS-ForestGEO network gave the data the necessary power, Myers said.",Both experiments provide strong evidence for negative plant-soil feedback mediated by soil biota.,"This is big result number one."" Two aspects of the CTFS-ForestGEO network gave the data the necessary power, Myers said. One is that the forest plots are large enough that they contain decent numbers of rare species, the other is that all of the trees in the plots have been tagged, mapped, measured and identified down to a small size class.","Such patterns of density and distance dependence are expected to emerge if the process of enemy-mediated negative feedback is operating in the plant community. Both experiments provide strong evidence for negative plant-soil feedback mediated by soil biota. In contrast, above-ground enemies (mammals, foliar herbivores and foliar pathogens) contributed little to negative feedback observed in the field.","[1.0, 1.0, 3.0, 1.0, 4.0]",Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/_tuiUVMBYc0/
10.1038/s41467-019-08876-w,Biology_519,"""But we still need to improve the antibodies' neutralization abilities and other aspects before it can become a viable vaccine.""","Consistent with the molecular dynamics simulation, we found that the C4S3 loop adopted a relatively rigid structure, as assessed by the low Bfactors (8-12 Å 2 , Supplementary Fig.","""It's important that we were able to generate an immune response to HIV and show that it's possible as a proof of concept,"" Dokholyan says. ""But we still need to improve the antibodies' neutralization abilities and other aspects before it can become a viable vaccine."" In the future, the protein design method could potentially help create and personalize vaccines for different diseases in various areas in the world.","The hydrophobic residue L86 also adopts a similar conformation to L265 of Env (Fig. Consistent with the molecular dynamics simulation, we found that the C4S3 loop adopted a relatively rigid structure, as assessed by the low Bfactors (8-12 Å 2 , Supplementary Fig. The two-dimensional 1 H-15 N heteronuclear single-quantum coherence (HSQC) spectrum suggests that C1S1 is well folded in solution (Fig.","[1.0, 2.0, 1.0, 1.0, 1.0]",Biology,train,1.2,news,http://ct.moreover.com/?a=38652836734&p=1pl&v=1&x=zTev5wuYIuxnuIqLKzhByA
10.1038/s41467-017-02722-7,Biology_521,"""These results suggest that we are exceptionally similar to our friends in how we perceive and respond to the world around us,"" they added.","As such, professionally directed movies and television shows elicit more reliable responses within and across subjects than unedited video footage or series of static photographs 38 .","The results revealed that the brain response of pairs who were identified as friends was more similar than pairs who were not friends. Similar Neural Response

""Neural similarity was associated with a dramatically increased likelihood of friendship,"" the researchers reported. ""These results suggest that we are exceptionally similar to our friends in how we perceive and respond to the world around us,"" they added.","Videos ranged in duration from 88 to 305 s ( Table 1) . As such, professionally directed movies and television shows elicit more reliable responses within and across subjects than unedited video footage or series of static photographs 38 . Such videos are engineered to engage viewers' attention and drive their inferences by inducing particular reactions and interpretations at specific times, and thus, are well-suited for experiments seeking to induce a shared series of cognitive states across subjects 18 .","[2.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.2,news,http://ct.moreover.com/?a=33154539729&p=1pl&v=1&x=9j332R5pf-bQLsWCLVmwbQ
10.1038/s41467-018-05287-1,Biology_522,"This corresponded to a cutoff of around 1,540 nanometers, which is in the infrared region.","1b , WG B possesses spectral characteristics equivalent to a waveguide with a smaller refractive index core, resulting in a smaller group index.","In a device using the same material for all waveguides, light tends to travel along the widest waveguide. This corresponded to a cutoff of around 1,540 nanometers, which is in the infrared region. When a light beam entered the filter, wavelengths measuring less than 1,540 nanometers could detect one wide waveguide on one side and three narrower waveguides on the other.","In Fig. 1b , WG B possesses spectral characteristics equivalent to a waveguide with a smaller refractive index core, resulting in a smaller group index. This idea of mimicking a continuous waveguide using segments smaller than the wavelength is similar to a sub-wavelength grating.","[1.0, 2.0, 2.0, 1.0, 1.0]",Biology,train,1.4,news,http://news.mit.edu/2018/chip-optical-filter-processes-wide-range-light-wavelengths-0801
10.1038/s41396-018-0222-x,Biology_525,"advertisement

Their work addresses three signature aspects of microbial communities.","That is to say, given its microbial partners, there is no need for a microbe to retain metabolic pathways utilizing nutrients which it never gets to use in any of the ""stable marriages"".","""It's almost like a rainforest in miniature."" advertisement

Their work addresses three signature aspects of microbial communities. Maslov again compares this aspect to a rainforest.","An intriguing possibility is that the evolutionary trajectory of each species may be shaped by its partners in the SMP. That is to say, given its microbial partners, there is no need for a microbe to retain metabolic pathways utilizing nutrients which it never gets to use in any of the ""stable marriages"". Over evolutionary time, such unused pathways would be dropped from its genome.","[3.0, 2.0, 2.0, 3.0]",Biology,train,2.5,news,http://ct.moreover.com/?a=34614781619&p=1pl&v=1&x=nQgxDzl4D_epBxPbxi2LfQ
10.1007/s00265-014-1810-z,Biology_526,Such scent signals are picked up from urine that stains the tree trunks rather than feces that accumulate on the ground under the trees.,On 15 of these occasions this behavior occurred in the general latrine area and on six occasions in an identified latrine tree.,"Droscher and Kappeler believe the latrines are a way in which to maintain familiarity and social bonding among members of a social unit, who otherwise have very little contact with each other. Such scent signals are picked up from urine that stains the tree trunks rather than feces that accumulate on the ground under the trees. Males visited the latrines more often during nights, when an intruder invaded the territory.",We could observe the focal animals on two occasions to lick and on 26 occasions to sniff the bark of a tree. On 15 of these occasions this behavior occurred in the general latrine area and on six occasions in an identified latrine tree. Experimental translocation of feces The time spent in the experimental latrine ranged between 11 % and 80 % (mean±SD = 29±23) of the observation time in females and between 11 and 39 % (20±7) in males.,"[1.0, 3.0, 1.0, 1.0]",Biology,train,1.5,news,http://www.sciencedaily.com/releases/2014/10/141015210846.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1126/scitranslmed.3006159,Biology_527,"The findings, published Nov. 6, 2013, in the journal Science Translational Medicine, advance efforts to develop bilateral movement in brain-controlled prosthetic devices for severely paralyzed patients.","Moreover, during online BMI control of bimanual movements, such multiplexing of the kinematics of both arms by individual neurons became even more prominent ( fig.","The findings, published Nov. 6, 2013, in the journal Science Translational Medicine, advance efforts to develop bilateral movement in brain-controlled prosthetic devices for severely paralyzed patients. ""Future brain-machine interfaces aimed at restoring mobility in humans will have to incorporate multiple limbs to greatly benefit severely paralyzed patients."" The monkeys first learned to control the avatar arms using a pair of joysticks, but were able to learn to use just their brain activity to move both avatar arms without moving their own arms.","Most neurons recorded in this study contributed to the predictions of kinematics of each arm ( fig. Moreover, during online BMI control of bimanual movements, such multiplexing of the kinematics of both arms by individual neurons became even more prominent ( fig. It should be emphasized that the distributed cortical representation of bimanual movements could not be described as a linear superposition of the representations of unimanual movements.","[1.0, 1.0, 1.0, 1.0, 3.0]",Biology,train,1.4,news,http://www.newswise.com/articles/monkeys-use-minds-to-move-two-virtual-arms
10.1126/sciadv.1500060,Biology_529,"Stevenson and Rillich found that compared with the crickets treated with nitric oxide suppressing drugs which tend to fight longer and have escalated aggression, the crickets treated with nitric oxide did not fight as long nor do they have escalated violence.","NO's effect is manifested in losers by prolonged avoidance behavior, characteristic for social defeat in numerous species.","They found that nitric oxide induces a flight response, which tells the losing cricket when enough is enough and it is time to run away from its aggressor. Stevenson and Rillich found that compared with the crickets treated with nitric oxide suppressing drugs which tend to fight longer and have escalated aggression, the crickets treated with nitric oxide did not fight as long nor do they have escalated violence. The observations suggest that deciding to flee from a conflict is influenced by nitric oxide that involuntarily acts on the nervous system.","Rather than suppressing aggressive motivation, NO increases susceptibility to aversive stimuli and with it the likelihood to flee. NO's effect is manifested in losers by prolonged avoidance behavior, characteristic for social defeat in numerous species. Intriguingly, fighting experience also induces, via NO, a brief susceptible period to aversive stimuli in winners just after victory.","[5.0, 4.0, 3.0, 3.0, 3.0]",Biology,train,3.6,news,http://www.techtimes.com/articles/39829/20150315/scientists-find-brain-chemical-that-determines-whether-to-fight-or-flee.htm
10.1053/j.gastro.2013.10.059,Biology_530,"However, when levels of liver and serum FGF21 were elevated, some white fat cells changed and became brown fat cells, which could increase whole-body oxygen consumption and produce more heat.",Body composition analysis showed that SIRT1 LKO mice had increased fat mass without changed lean mass.,"It also led to decreased levels of liver FGF21, which were associated with abnormal fat metabolic changes in liver and adipose tissues. However, when levels of liver and serum FGF21 were elevated, some white fat cells changed and became brown fat cells, which could increase whole-body oxygen consumption and produce more heat. These changes in the fat cells caused by elevated FGF21 protein could help explain how the experimental mice experienced more weight loss, had less fat mass and slowed the progression of fatty liver.","SIRT1 LKO mice appeared to have increased adiposity with more visible fat, possibly due to increased adipocyte cell size. Body composition analysis showed that SIRT1 LKO mice had increased fat mass without changed lean mass. Daily food intake was similar between WT and SIRT1 LKO mice on a regular chow diet.","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,news,http://www.sciencedaily.com/releases/2014/01/140122104127.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s12915-014-0076-2,Biology_531,Prokaryotic cells can be compared to a factory composed of open space where the various employees work side by side.,"The presence of a significant α-proteobacterial contribution to all eukaryotic genomes, even those that lack mitochondria or hydrogenosomes, shows that a close association with mitochondria evolved in the eukaryotic stem lineage .","In this way, multiple membrane-bound organelles begin to work together to perform the life processes much more effectively than in a prokaryotic cell. Prokaryotic cells can be compared to a factory composed of open space where the various employees work side by side. This may have helped them crack the code on the formation of complex life.","We suggest that external protrusions evolved in the original proto-eukaryote to facilitate resource exchange with ectosymbiotic bacteria that ultimately gave rise to modern day mitochondria. The presence of a significant α-proteobacterial contribution to all eukaryotic genomes, even those that lack mitochondria or hydrogenosomes, shows that a close association with mitochondria evolved in the eukaryotic stem lineage . This illustrates the ecological plausibility of progenitors of mitochondria being ectosymbiotic bacteria that entered into a metabolic mutualism with the progenitor of the host cell.","[1.0, 1.0, 2.0, 1.0, 1.0]",Biology,train,1.2,news,http://guardianlv.com/2014/10/scientists-may-have-cracked-the-code-on-formation-of-complex-life/
10.1038/ncomms3489,Biology_532,"""This is consistent with the fossil record, and also with the hypothesis that symmetric 'flight' feathers first evolved in dinosaurs for non-aerodynamic functions, later being adapted to form aerodynamically capable surfaces,"" Dyke said.","4) , there is very little difference in L/D between feathered and unfeathered models.","""Significant to the evolution of flight, we show that microraptor did not require a sophisticated, 'modern' wing morphology to undertake effective glides, as the high-lift coefficient regime is less dependent upon detail of wing morphology,"" said Gareth Dyke, a senior lecturer in vertebrate palaeontology at the University of Southampton and co-author of the study, which was published in the journal Nature Communications. ""This is consistent with the fossil record, and also with the hypothesis that symmetric 'flight' feathers first evolved in dinosaurs for non-aerodynamic functions, later being adapted to form aerodynamically capable surfaces,"" Dyke said. Roeland de Kat, study co-author and research fellow in aerodynamics and flight mechanics at University of Southampton, found the wind tunnel simulations enlightening.","Flat-plate experiments show that in the region of sustained stable flight (that is, regions of high C R ; Fig. 4) , there is very little difference in L/D between feathered and unfeathered models. The most important factor for this theropod was attaining sufficient wing area (for which derived feathers are unnecessary) to glide most effectively; theoretically, all Microraptor needed in order to glide at high C R would was an impervious surface.","[2.0, 4.0, 2.0, 2.0, 2.0]",Biology,train,2.4,news,http://www.natureworldnews.com/articles/4042/20130918/wind-tunnel-used-study-evolution-dinosaur-flight.htm
10.1073/pnas.1709200115,Biology_533,"Chicks in both the quietest and loudest areas had reduced feather growth and body size, leaving a sweet spot in areas of moderate noise where nestlings seemed to grow fastest.",The finding of a negative linear relationship between noise disturbance and baseline cort strongly suggests that suppression of baseline cort occurs in response to the acoustic disturbance gradient.,"""In this study, we were able to demonstrate that dysregulation due to noise has reproductive consequences."" Chicks in both the quietest and loudest areas had reduced feather growth and body size, leaving a sweet spot in areas of moderate noise where nestlings seemed to grow fastest. Meanwhile, in the loudest areas, the machinery noise masks calls from other birds - a signal of whether predators are present - chronically stressing moms and nestlings.","This result, which was consistent across species, supports our prediction that chronic anthropogenic noise exposure is an explanatory factor affecting GC signaling. The finding of a negative linear relationship between noise disturbance and baseline cort strongly suggests that suppression of baseline cort occurs in response to the acoustic disturbance gradient. While it remains possible that individual GC responsiveness affects nest site selection, we do not find any evidence of self-sorting based on other quality factors, e.g., body size (Table S1 ).","[3.0, 4.0, 2.0, 2.0]",Biology,train,2.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/RJD7qdoYZA0/
10.1016/j.celrep.2013.07.030,Biology_534,"In the study, the average lifespan for engineered mice was 28 months for males and 31.5 months for females, compared to 22.9 for males and 26.5 for females in normal mice.","When food intake was normalized to body weight, mTOR D/D mice and WT mice consumed equivalent amount of calories ( Figure 2C ).","In humans, that's equal to gaining about 16 years. In the study, the average lifespan for engineered mice was 28 months for males and 31.5 months for females, compared to 22.9 for males and 26.5 for females in normal mice. The engineered mice, although smaller than the normal mice, also had better memory and coordination, and had stronger muscles.","Analysis of body size ( Figure 2A ) and body weight ( Figure 2B ) revealed that mTOR D/D mice were consistently smaller than their WT littermates, although normalized body composition was unchanged ( Figure S2A ). When food intake was normalized to body weight, mTOR D/D mice and WT mice consumed equivalent amount of calories ( Figure 2C ). mice revealed no significant alterations in glucose tolerance (Figure 2D) or insulin sensitivity ( Figure 2E ).","[1.0, 1.0, 1.0, 2.0, 1.0]",Biology,train,1.2,news,http://www.businessinsider.com/lowered-mtor-increases-longevity-2013-9
10.1098/rspb.2016.0496,Biology_535,"We found that the epidemic was solely driven by the chromosome region of the bacterial genome.""",Our evidence of selective sweeps restricted to the CHR suggests that selection among CHR variants in the soil (i.e.,"They found that a handful of bacterial strains dominate local populations of plants and have spread across the state. We found that the epidemic was solely driven by the chromosome region of the bacterial genome."" Sachs noted that the epidemic strains are highly successful in the soil and in competition to infect plants, explaining perhaps why they persist and dominate in many different places.","The rhizobial lineages both Bradyrhizobium and Mesorhizobium exhibit genomes with 'expression islands', wherein SI loci are primarily expressed in nodules and CHR loci are primarily expressed ex planta . Our evidence of selective sweeps restricted to the CHR suggests that selection among CHR variants in the soil (i.e. outside the context of in planta symbiosis) might be the driving force structuring these populations.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.seeddaily.com/reports/Bacteria_beneficial_to_plants_have_spread_across_California_999.html
10.1073/pnas.1307090110,Biology_536,"Along the way, a major milestone logged was the genome sequencing and analysis of the first member of the archaeal branch of the tree of life ever isolated from a polar environment.","Secondary replicons in DL31, H. lacusprofundi and DL1 had consistently lower codon adaptation (CAI) and codon bias (CBI) indexes than the primary replicons.","Cavicchioli acknowledged that the PNAS paper represents the synthesis of the more striking findings that arose from merging and analyzing collective data sets that have been assembled over the last eight years. Along the way, a major milestone logged was the genome sequencing and analysis of the first member of the archaeal branch of the tree of life ever isolated from a polar environment. ""Every time we 'poke an omics stick' in there we find things we never expected,"" Cavicchioli said.","The unassigned metagenome data could derive from viruses and/or eucarya that are not in the National Center for Biotechnology Information database (SI Appendix). Secondary replicons in DL31, H. lacusprofundi and DL1 had consistently lower codon adaptation (CAI) and codon bias (CBI) indexes than the primary replicons. Additionally, the primary replicons of tADL and DL1 possessed extended regions with low CAI/CBI.","[1.0, 1.0, 1.0, 2.0, 1.0]",Biology,train,1.2,news,http://www.sciencedaily.com/releases/2013/09/130930152743.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-018-06106-3,Biology_537,The new protective mechanism is based on oxygen-consuming enzymes that draw their energy from sugar.,The pH value of the buffer solution changed during catalysis from 7.4 at the beginning to 4.4 at the end of the experiment due to the formation of gluconolactone which is readily hydrolyzed to gluconic acid.,"The new protective mechanism is based on oxygen-consuming enzymes that draw their energy from sugar. The researchers showed that they were able to use this protective mechanism to produce a functional biofuel cell that works with hydrogen and glucose as fuel. ""However, this mechanism consumed electrons, which reduced the performance of the fuel cell,"" says Adrian Ruff.","Evidently, there must be an additional reason for the deactivation of the polymer entrapped hydrogenase, which is not due to the presence of O 2 . The pH value of the buffer solution changed during catalysis from 7.4 at the beginning to 4.4 at the end of the experiment due to the formation of gluconolactone which is readily hydrolyzed to gluconic acid. In combination with the protons generated by the conversion of H 2 at the bioanode, the local concentration of H + within the polymer/enzyme film exceeds the buffer capacity in the solvated hydrogel and the pH drops to a critical value at which the enzyme is disintegrated.","[2.0, 2.0, 1.0, 1.0]",Biology,train,1.5,news,http://ct.moreover.com/?a=37129855277&p=1pl&v=1&x=exTYpoiEi-q_6_cMNNANXQ
10.1073/pnas.0403120101,Biology_538,She argues that the DNA results in the study released this week are far from conclusive.,"Similarly, the various BAII models, which argue for no clear phylogenetic signal, are also rejected by the results of our analyses.","A subsequent analysis by Cooper and his colleagues of the DNA from the Chilean finds challenged the dates and suggested that the genetic mutation originally thought to have come from Polynesian forebears was in fact a fairly common mutation found in chickens throughout the world. She argues that the DNA results in the study released this week are far from conclusive. ""Using modern DNA to understand what people were doing in the past is like sampling a group of commuters at a London Tube station at rush hour.","Specifically, the somewhat simplistic ETP set of models, although perhaps appropriate for describing the spread of the Austronesian languages (43) , are inadequate for biological data in general and for our R. exulans data in particular. Similarly, the various BAII models, which argue for no clear phylogenetic signal, are also rejected by the results of our analyses. In contrast, our data do support the voyaging corridor aspect of both the SBB and the VC Triple-I models, but at this point, with no R. exulans evidence linking Near and Remote Oceania, we would have to suggest that haplogroup III R. exulans was an intrusive component of Lapita, and we therefore find strongest support for Green's VC Triple-I model.","[1.0, 5.0, 4.0, 1.0, 1.0]",Biology,train,1.0,news,http://news.nationalgeographic.com/news/2014/03/140318-polynesian-chickens-pacific-migration-america-science/
10.1126/scitranslmed.aaa8419,Biology_539,"In the current study, the scientists demonstrated that NCMs hidden in the donor lung are the culprit ultimately responsible for initiating the damaging inflow of neutrophils following transplantation of that lung.",We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum.,"Further, targeting the patient's neutrophils was not considered to be a practical strategy for treatment, given that those same cells are critical for defending the body against pathogens. In the current study, the scientists demonstrated that NCMs hidden in the donor lung are the culprit ultimately responsible for initiating the damaging inflow of neutrophils following transplantation of that lung. But the scientists discovered that NCMs -- a type of immune cell whose structure and function have only recently been described -- are actually retained in the blood vessels of the donor lung.","This patient was shown to have systemic M. hominis infection . We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum. On postoperative day 12, he developed mental status changes, and his ammonia concentration was 549 mM.","[3.0, 3.0, 1.0, 1.0]",Biology,train,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/kReDhZ6Y_nY/
10.1073/pnas.1405000111,Biology_54,"Contrary to common hypotheses, they found that the most likely origin of migration in this group lay in ancestral species that resided in North America and gradually moved further and further south for the winter.","Contrary to expectations, we found that long-distance migration primarily evolved through evolutionary shifts of geographic range south for the winter out of North America, as opposed to north for the summer.","Their work also offers evidence that many tropical bird species descended from migratory ancestors that lost migration. Contrary to common hypotheses, they found that the most likely origin of migration in this group lay in ancestral species that resided in North America and gradually moved further and further south for the winter. Shifts in range from North America to tropical areas were the dominant pathway for geographical change, and evolved much more frequently than shifts northward from tropical areas.","These results illuminate how the evolution of seasonal migration has contributed to greater niche conservatism among tropical members of this diverse avian radiation. Contrary to expectations, we found that long-distance migration primarily evolved through evolutionary shifts of geographic range south for the winter out of North America, as opposed to north for the summer. Our results further suggest that seasonal migration promoted colonization of the tropics from North America.","[4.0, 5.0, 5.0, 4.0]",Biology,train,4.5,news,http://www.newswise.com/articles/study-traces-evolutionary-origins-of-migration-in-new-world-birds
10.1016/j.cell.2016.02.014,Biology_540,"""We thought that, under the same conditions if the cells are identical, that both would differentiate the same way, but that is not what we found,"" Jang said.","Nrf2 inhibition during differentiation further increased the percentages of G1 cells and ciliated cells ( Figures S7B and S7C) , confirming that these changes are features of early NE derivation.","This is significant, Kosik noted, because Nrf2 doesn't usually diminish until the cell has already started to differentiate. ""We thought that, under the same conditions if the cells are identical, that both would differentiate the same way, but that is not what we found,"" Jang said. ""Cell fate is controlled by G 1 lengthening, which extends cilia's exposure to signals from their environment.","Furthermore, the G1 lengthening during NE differentiation mirrored changes in the ciliation pattern with a significant shift that occurred between day 0 and day 2 ( Figure 5B ). Nrf2 inhibition during differentiation further increased the percentages of G1 cells and ciliated cells ( Figures S7B and S7C) , confirming that these changes are features of early NE derivation. Consistent with the data from propidium iodide staining, an increased number of red fluorescent cells was observed even at day 1 of NE differentiation, while no significant change was detected during ME differentiation ( Figures 5C and S7D ).","[2.0, 4.0, 3.0, 3.0]",Biology,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/fJ8yn-nb8pQ/
10.1098/rsif.2014.0985,Biology_541,"""Our results are based on the activity of ants but we are convinced that our main conclusion that the duration of an activity event is determined before it commences is likely to be applicable as a general principle of animal behavior across taxa, including humans,"" the researchers think.","The power-law relationship between mean event speed and event duration as well as the significant difference between the exponents for large and small nest were robust to these changes (electronic supplementary material, tables S3 and S4).","Interestingly, study of ant behavior provides some new insights to this old and very intriguing question. ""Our results are based on the activity of ants but we are convinced that our main conclusion that the duration of an activity event is determined before it commences is likely to be applicable as a general principle of animal behavior across taxa, including humans,"" the researchers think. ""Universality in relationships at the social level, such as between the size of cities and measures of income, innovation and even the pace of life are stimulating the development of a unified theory of urban living.","The above results obtained from data coarse-grained to a time unit of Dt ¼ 0.8 s were replicated when the data were coarse-grained to time units of 0.2, 0.4, 1.6 and 3.2 s (electronic supplementary material, tables S3 and S4). The power-law relationship between mean event speed and event duration as well as the significant difference between the exponents for large and small nest were robust to these changes (electronic supplementary material, tables S3 and S4). This procedure removes any correlations between the speeds and the events.","[1.0, 3.0, 2.0, 1.0, 1.0]",Biology,train,1.6,news,http://www.technology.org/2014/11/25/scientists-discovered-universal-pattern-ant-behavior/
10.1038/s41467-018-07490-6,Biology_543,"This is not ideal, especially when treating chronic progressive eye diseases that require slow and sustained treatment, such as glaucoma.""",These observations indicated that tumour cells can be efficiently destroyed by activated Dox.,"Prof Chen added, ""These two current methods only produce a burst release of drug with a short effective duration. This is not ideal, especially when treating chronic progressive eye diseases that require slow and sustained treatment, such as glaucoma."" In mice with the patches applied, there was a 90 per cent reduction in the area of blood vessels with a single treatment dose of 1 microgram.","5h , the 2-2 h-TCO-Dox treatment group exhibited necrotic lesions of the tumours, exhibiting cell shrinkage, loss of contact and coagulation, which was similar to the tumours treated with Dox. These observations indicated that tumour cells can be efficiently destroyed by activated Dox. However, histopathological images of the tumours treated with saline, 2 or TCO-Dox demonstrated that the HeLa cells remained normal.","[1.0, 2.0, 2.0, 1.0, 1.0]",Biology,train,1.4,news,http://ct.moreover.com/?a=37749144844&p=1pl&v=1&x=tuBpyE-b3WhK7LvlqlLnrg
10.1126/sciadv.aaq1442,Biology_544,This may be important for use in sensors and actuators.,"Thus, for a polymorph a in an alloy system A 1−x B x , the enthalpy DH a (V,x) can be calculated as Here, DH poly, a (x) = (1 − x) DE A,a + x DE B,a is the ideal component of the mixing enthalpy, determined as the polymorph energy interpolated between the end-member compounds; DH W,a (x) = W a x(1 − x) is the nonideal component of the mixing enthalpy arising from interactions between dissimilar substituents of the alloy, with the interaction parameter W a quantifying the enthalpic strength of these interactions and the resulting bowing of the mixing enthalpy; and DH vol (V) is the energetic contribution from volume changes (see the Supplementary Materials for details).","Unlike its parents, the new material is piezoelectric - able to generate an electric charge in response to applied mechanical stress. This may be important for use in sensors and actuators. Pioneering Work on Mismatched Materials

The experiment builds on pioneering work led by NREL on mixing compounds with atomic structures that didn't match.","However, in an alloy, the polymorph enthalpy DH depends not only on the formation enthalpy and the atomic volume but also on the enthalpic cost to mix the alloy constituents DH mix (x). Thus, for a polymorph a in an alloy system A 1−x B x , the enthalpy DH a (V,x) can be calculated as Here, DH poly, a (x) = (1 − x) DE A,a + x DE B,a is the ideal component of the mixing enthalpy, determined as the polymorph energy interpolated between the end-member compounds; DH W,a (x) = W a x(1 − x) is the nonideal component of the mixing enthalpy arising from interactions between dissimilar substituents of the alloy, with the interaction parameter W a quantifying the enthalpic strength of these interactions and the resulting bowing of the mixing enthalpy; and DH vol (V) is the energetic contribution from volume changes (see the Supplementary Materials for details). Figure 1A shows the DH(V) projection of DH(V,x) for the three considered polymorphs at x = 0, and Fig.","[2.0, 3.0, 1.0, 1.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=33938749265&p=1pl&v=1&x=rkwmusOGxwC6SYK2Q_8mEw
10.1073/pnas.1405237111,Biology_547,The variability in those measurements was impressive and interesting in a couple ways.,"For the two major compounds required for the CCaT, GDGT-0 and GDGT-5, we obtained 3,047 valid spectra (signal-to-noise ratio, SNR > 5; cf.","Measured ratios of a pair of lipids matched up quite well between the two, showing that the laser technique does indeed work. The variability in those measurements was impressive and interesting in a couple ways. First, there's the sharper telescope.","correlated with the LC-based TEX 86 (r 2 = 0.95, P < 0.0001; Fig. For the two major compounds required for the CCaT, GDGT-0 and GDGT-5, we obtained 3,047 valid spectra (signal-to-noise ratio, SNR > 5; cf. The two minor compounds GDGT-1 and GDGT-2 were observed in adequate abundance (SNR > 5) in 38% of all spectra, and GDGT-3 in only 13% of the spectra.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://arstechnica.com/science/2014/11/more-detailed-paleoclimate-records-brought-to-you-by-lasers/
10.1038/s41467-018-05201-9,Biology_548,"Just as earning or saving potential is learned in our experimental economic game, we believe our pro-earning and anti-savings bias is learned.","While unpleasant events typically evoke relatively stronger changes in affect and attention in both perceptual and decision studies 36 , gains also play a similar role .","Not only does this take a personal toll, but it also strengthens our already misplaced emphasis on earning over saving. Just as earning or saving potential is learned in our experimental economic game, we believe our pro-earning and anti-savings bias is learned. That's good news, because if we've learned it, then we can unlearn it.","By paying attention, an individual is able to impact the salience 33 and value 34 of sensory events. While unpleasant events typically evoke relatively stronger changes in affect and attention in both perceptual and decision studies 36 , gains also play a similar role . Importantly, value not only alters attention, but attention is also central to value, with attention-boosting 34 and inattentionreducing value 40 .","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=37418801583&p=1pl&v=1&x=73RW7lb6WKJLSPi8PSOEbQ
10.1007/s13592-015-0356-z,Biology_549,"Contrary to the fears of alarmists, however, honey bees aren't going to disappear from the face of the earth.","There was no difference between migratory and non-migratory in commercial groups, but the P value was close to 0.05 (P =0.065).","Now, you're lucky to get one season before Her Majesty dies or needs to be replaced. Contrary to the fears of alarmists, however, honey bees aren't going to disappear from the face of the earth. And she helped gather Minnesota data for this year's survey, as she has in the past, but that may be among the least of her credentials on this subject.","The only significant difference found was migratory sideline beekeepers which had lower losses compared to non-migratory sideline beekeepers (Kruskal-Wallis χ 2 =7.1623, Mann-Whitney P =0.007445). There was no difference between migratory and non-migratory in commercial groups, but the P value was close to 0.05 (P =0.065). Losses of sideline beekeepers using their colonies to pollinate almond was not different than non-pollinator losses, but the P value was again close to 0.05 (P =0.060).","[2.0, 2.0, 1.0, 1.0, 1.0]",Biology,train,1.4,news,http://www.minnpost.com/earth-journal/2015/05/looking-behind-grim-new-numbers-bee-die-offs-and-what-drives-them
10.1098/rsos.171474,Biology_55,"""We found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games,"" they report.",The semi-partial effect relating violent gaming to aggressive behaviour was r ¼ 0.01.,"In Przybylski and Weinstein's review of prior literature, the two researchers strongly argue that earlier research is beset with such problems. ""We found adolescents were not more or less likely to engage in aggressive or prosocial behaviours as a function of the amount of time they devoted to playing violent games,"" they report. Przybylski and Weinstein add, ""This pattern of findings further suggests that links reported in the literature might be influenced by publication bias, selective reporting, or an artefact of unobserved or hidden moderators.""","larger) to findings present in the existing literature , and in line with proposed minimum practical media effect sizes [72] . The semi-partial effect relating violent gaming to aggressive behaviour was r ¼ 0.01. Further, we derived a 95% coincidence interval around this point estimate that ranged from 20.08 to 0.10 using a bootstrapping approach with 10 000 iterations.","[4.0, 1.0, 4.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1038/s41593-019-0414-3,Biology_550,"""These two fields are really benefitting one another,"" he said.","Furthermore, we show that the strength of persistent activity covaries with the degree of manipulation, potentially explaining the observation that persistent activity varies markedly between tasks.","Complementary fields of research

The study demonstrates how valuable AI has become to the study of neuroscience, and how the two fields inform each other. This also makes biologically-inspired AI networks better platforms for testing ideas about functions of the real brain functions. ""These two fields are really benefitting one another,"" he said.","We show that STSP can support the activity-silent maintenance of information, but that it cannot support the silent manipulation of information. Furthermore, we show that the strength of persistent activity covaries with the degree of manipulation, potentially explaining the observation that persistent activity varies markedly between tasks. We found that short-term synaptic plasticity can support the short-term maintenance of information, provided that the memory delay period is sufficiently short.","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=39430535213&p=1pl&v=1&x=x1sCldipACBVxYyilAInYA
10.1038/s41592-018-0108-x,Biology_551,"""If we are able to predict how a tumour will evolve, the treatment could be altered before adaptation and drug resistance ever occur, putting us one step ahead of the cancer.","Probability rising, instead, is a measure of the degree of association between two variables, which implies statistical dependence, as it is symmetric (like correlation); see Supplementary Note 2 for further discussion.","""By giving us a peek into the future, we could potentially use this AI tool to intervene at an earlier stage, predicting cancer's next move."" ""If we are able to predict how a tumour will evolve, the treatment could be altered before adaptation and drug resistance ever occur, putting us one step ahead of the cancer. ""This new approach using AI could allow treatment to be personalised in a more detailed way and at an earlier stage than is currently possible, tailoring it to the characteristics of each individual tumour and to predictions of what that tumour will look like in the future.""","Binary data are lowerresolution than CCFs but can still be used to create a mutation tree for a patient. Probability rising, instead, is a measure of the degree of association between two variables, which implies statistical dependence, as it is symmetric (like correlation); see Supplementary Note 2 for further discussion. So, it can be used to generate all minimum spanning trees rooted in the clonal group, which is the one whose alterations appear in all samples.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34971680828&p=1pl&v=1&x=2ZAxri6ch0bE8qnsaM4yzg
10.1038/ng.3303,Biology_553,"""These findings are a major advance in understanding the genes that play a role in autism,"" said study author Raphael Bernier, associate professor of psychology and behavioral sciences at the University of Washington.",Observation of the resulting histogram and observed values suggests that genes enriched for de novo mutations do not overlap with genes enriched for inherited LGD mutations or rare disruptive CNVs (Supplementary Fig.,"The scientists were able to compare both small mutations of single base-pairs in DNA and larger deletions and duplications of the genome. ""These findings are a major advance in understanding the genes that play a role in autism,"" said study author Raphael Bernier, associate professor of psychology and behavioral sciences at the University of Washington. ""Knowing more about these genes will set the stage for personalized medicine by allowing for targeted treatments specific to an individual.","In this model, the simple sum was again significant (OR = 1.20, P = 0.002), but the squared sum term was not (OR = 1.00, P = 0.59). Observation of the resulting histogram and observed values suggests that genes enriched for de novo mutations do not overlap with genes enriched for inherited LGD mutations or rare disruptive CNVs (Supplementary Fig. 9 ).","[3.0, 1.0, 3.0, 1.0, 1.0]",Biology,train,1.8,news,http://www.redorbit.com/news/health/1113389906/looking-for-a-genetic-cause-of-autism-051315/
10.1126/scitranslmed.3005656,Biology_554,"The drug, they showed, could be given systemically or injected directly into the brain, and administered before or shortly after the mice were immobilized.","A significant interaction of genotype and type of conditioned stimulus (F 1,118 = 4.4; P < 0.05, ANOVA) indicated that G allele carriers did not discriminate on the FPS response between danger signals (+) and safety signals (−) during late fear conditioning.","They homed in on one gene that was expressed in the brain and significantly turned down in the PTSD-like mice when compared to other mice. The drug, they showed, could be given systemically or injected directly into the brain, and administered before or shortly after the mice were immobilized. In all cases, it blocked the formation of PTSD symptoms in the animals.","Given the above finding, we collapsed the GG and GC genotypes into G allele carriers versus the CC genotype during differential fear conditioning, in which one conditioned stimulus was paired with an aversive airblast (+), whereas a second conditioned stimulus was not (−) . A significant interaction of genotype and type of conditioned stimulus (F 1,118 = 4.4; P < 0.05, ANOVA) indicated that G allele carriers did not discriminate on the FPS response between danger signals (+) and safety signals (−) during late fear conditioning. In contrast, those with the CC genotype showed an increase in the FPS response to the (+) conditioned stimulus versus the (−) conditioned stimulus (F 1,69 = 12.3; P ≤ 0.001, ANOVA; Fig.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.newswise.com/articles/drug-prevents-post-traumatic-stress-like-symptoms-in-mice
10.1152/ajpheart.00712.2016,Biology_555,"""So when you take out this enzyme, and you have elastin and collagen that aren't cross-linked, they have totally different mechanical behavior.","Even though Lox Ϫ/Ϫ AAs and DAs have fragmented elastic laminae and disorganized SMCs, the unloaded outer diameter and wall thickness were similar to Lox ϩ/ϩ AAs and DAs.","In the LOX deficient mice, they observed changes in mechanical behavior and in signaling of groups of genes that appeared to be a susceptibility differentiator in certain sections of tissue; the way they interacted seemed to provide some protection against aneurysm. ""So when you take out this enzyme, and you have elastin and collagen that aren't cross-linked, they have totally different mechanical behavior. We expect to see those mechanical differences, but we found that there's this combination of the mechanics and the gene signaling that work together to lead to an aneurysm.""","LOX inactivation could also change the expression of secreted factors, the structural matrix, and matrixassociated proteins that constitute the aortic matrisome. Even though Lox Ϫ/Ϫ AAs and DAs have fragmented elastic laminae and disorganized SMCs, the unloaded outer diameter and wall thickness were similar to Lox ϩ/ϩ AAs and DAs. Lox Ϫ/Ϫ AAs and DAs have altered opening angles, circumferential stresses, and circumferential stretch ratios; however, only Lox Ϫ/Ϫ AAs have increased pressurized diameters and tangent moduli.","[1.0, 1.0, 1.0, 3.0]",Biology,train,1.5,news,http://healthmedicinet.com/news/engineers-examine-chemo-mechanics-of-heart-defect/
10.1038/srep28535,Biology_557,"He continues, ""Changing the combination of both fluorescent proteins and an elastic linker used in the current research was the key in giving us the outcome we got.",The tension sensor demonstrated a clear distinction between prospective neural ectoderm and epidermal ectoderm.,"""This study measuring the tensile forces of cells in whole African clawed frog embryos without invasion and fixation is one of the only successful cases in the world, the only other example being that confirmed in a nematode,"" says Michiue. He continues, ""Changing the combination of both fluorescent proteins and an elastic linker used in the current research was the key in giving us the outcome we got. Even though clawed frog embryos are not necessarily suitable for fluorescent imaging, that we succeeded in FRET measurement shows that the probe may be applicable for measuring tension in many other types of embryos, tissues, and organs.","When the sensor is under tension, the elastic linker is stretched and the fluorescent domains are separated, resulting in a decrease of FRET efficiency between the two fluorescent domains. The tension sensor demonstrated a clear distinction between prospective neural ectoderm and epidermal ectoderm. We also found that the neural and lateral epidermal ectoderms underwent similar morphogenesis, whereas their individual cells behaved differently.","[2.0, 3.0, 1.0, 1.0]",Biology,train,1.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/CBwVYLjoOuM/
10.1126/scisignal.2005237,Biology_559,They discovered that the intensity and frequency of calcium impulses undergo extreme variation  both cell-internally and cell-to-cell.,"In some recordings, there was a linear trend through the entire ISI sequence (see top panels of Fig.","(Credit: LCSB 2014)

The instruments in an orchestra produce signals  musical notes  by causing the air to vibrate. They discovered that the intensity and frequency of calcium impulses undergo extreme variation  both cell-internally and cell-to-cell. Accordingly, the information they convey cannot be interpreted by analyzing isolated signals alone.","In some sequences of Ca 2+ spikes, the stationary phase was preceded by an initial transient in the ISI (see Fig. In some recordings, there was a linear trend through the entire ISI sequence (see top panels of Fig. Such a trend, which may reflect slow changes in cellular sensitivity, is not the result of a stochastic process, but it would exaggerate the randomness of ISIs (increase s) if it were not removed.","[1.0, 1.0, 1.0, 2.0]",Biology,train,1.25,news,http://www.nanowerk.com/news2/biotech/newsid=36377.php
10.3945/jn.113.188441,Biology_56,"Eating instant noodles at least twice a week was associated with 68% more cardiometabolic syndrome for women, regardless of what else their diet was made up of.","The consumption of instant noodles was associated with increased prevalence of metabolic syndrome in women, independent of major dietary patterns.","Neither of those diets on the whole were associated with an uptick in cardio-metabolic syndrome--which is a collection of risk factors for heart disease, type-2 diabetes and stroke including high blood pressure, blood sugar, and cholesterol. Eating instant noodles at least twice a week was associated with 68% more cardiometabolic syndrome for women, regardless of what else their diet was made up of. This effect was only seen in women.","The 2 major dietary patterns were associated with distinct cardiometabolic risk factors. The consumption of instant noodles was associated with increased prevalence of metabolic syndrome in women, independent of major dietary patterns. The prevalence of overweight in the adult population increased from 26% in 1998 to 32% in 2007 (1) and that of metabolic syndrome in the adult population increased from 25% to 31% in the same time period .","[5.0, 4.0, 4.0, 4.0]",Biology,train,4.25,news,http://time.com/3149497/instant-noodles-heart-risks/
10.1046/j.1523-1739.2002.00306.x,Biology_561,"""We hope [the study] will inspire additional investment in post-war restoration,"" Daskin said, ""in wildlife and their habitats, but also in the socioeconomic conditions that are necessary for supporting wildlife conservation.""",Rates of deforestation in Cambodia increased exponentially following the end of the Cambodian civil war as the result of large-scale commercial logging controlled and orchestrated by military field commanders and corrupt forestry officials.,"Daskin said that wildlife populations have an amazing ability to recover after a human conflict, even if they sustain significant losses due to poaching, hunting, habitat loss, or perhaps being caught in crossfire. ""We hope [the study] will inspire additional investment in post-war restoration,"" Daskin said, ""in wildlife and their habitats, but also in the socioeconomic conditions that are necessary for supporting wildlife conservation."" With local agricultural assistance, conservation education for children, and collaborative ecological restoration on both sides of the conflict, the area has seen a massive resurgence in animal biodiversity, and even some alleviation in human poverty.","The looting of landscapes begun during wars can continue unabated into peacetime and may even increase, given circumstances that ensure a lack of military preoccupation with combat activities and a concurrent absence of effective civilian government authority. Rates of deforestation in Cambodia increased exponentially following the end of the Cambodian civil war as the result of large-scale commercial logging controlled and orchestrated by military field commanders and corrupt forestry officials. In instances where government institutions have been overthrown or ceased to function, local nongovernmental organizations and conservationists can help maintain continuity in conservation programs in the absence of support from central government or international organizations.","[2.0, 3.0, 2.0, 2.0, 4.0]",Biology,train,2.6,news,http://ct.moreover.com/?a=32987960103&p=1pl&v=1&x=o0fr_iWaqTQ7yseajK7ooA
10.1038/s41467-017-02515-y,Biology_564,Exceptional conditions allowed the dinosaur's feathers to fossilize along with its bones.,"Unlike oviraptorosaurs and dromaeosaurids, but as in troodontids, other Tiaojishan theropods, and some basal avialans, ossified sternum and uncinate processes are absent.","aI was shocked by its beautifully preserved feathers, even though I had seen many feathered dinosaur fossils previously,a adds Xu. Exceptional conditions allowed the dinosaur's feathers to fossilize along with its bones. On Caihongas head, chest, and parts of its tail, the researchers saw melanosomes that were long, flat, and organized into sheets.","The furcula is relatively slender. Unlike oviraptorosaurs and dromaeosaurids, but as in troodontids, other Tiaojishan theropods, and some basal avialans, ossified sternum and uncinate processes are absent. The forelimbs in Caihong measure only about 60% the hindlimb length, proportionally shorter than most other basal paravians 23 .","[1.0, 2.0, 2.0, 1.0, 2.0]",Biology,train,1.6,news,https://news.nationalgeographic.com/2018/01/new-dinosaur-rainbow-feathers-china-caihong-paleontology-science/
10.1186/s12896-018-0443-0,Biology_565,"This makes the approval process much simpler, meaning that the product should be available in ordinary pharmacies as early as 2021.","The SDS gel showed four dominant protein bands, which all contained the refolded product.","Although initial clinical studies are underway, they will not lead to a marketable product in the next few years. This makes the approval process much simpler, meaning that the product should be available in ordinary pharmacies as early as 2021. ""It can easily happen that the proteins are not folded exactly as we want.""","4) . The SDS gel showed four dominant protein bands, which all contained the refolded product. Host cell proteins were only found to a small portion in the lowest band, indicating a high purity of the refolded product.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=37220751822&p=1pl&v=1&x=6YR6bfGHO778gzMZlSExag
10.1038/ncomms6451,Biology_566,"They're very high density, compact rocks.""","Hence, the effect of initial matrix porosity on post-shock temperature provides a good measure of the sensitivity of the temperature estimates to all model assumptions.","""But the meteorites we look at are not little fluff balls. They're very high density, compact rocks."" Other factors fail to account for the density change.","Of the assumed model parameters, peak-and post-shock matrix temperatures are most sensitive to the initial porosity of the matrix. Hence, the effect of initial matrix porosity on post-shock temperature provides a good measure of the sensitivity of the temperature estimates to all model assumptions. In simulations that varied the initial matrix porosity between 60 and 80%, we observed increasing post-shock matrix temperature with increasing initial porosity, for the same impact velocity (Table 1 , main text).","[2.0, 2.0, 1.0, 1.0, 1.0]",Biology,train,1.4,news,http://www.sciencedaily.com/releases/2015/01/150119090949.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.neuron.2016.05.020,Biology_567,"That way you can have parallel processes in the brain for different behaviors.""","Initially, males spent $80% of their time engaged in mating behaviors (courtship and copulation), but the percentage gradually declined to $10% over 4 hr ( Figures 1A and S1A , available online).","Rogulja added, ""You'd rather change the way all that information gets transformed into purposeful motor output. That way you can have parallel processes in the brain for different behaviors."" The researchers emphasize that they were able to quickly translate their findings into a theory of how motivation works at a neurological level because so much was already known about dopamine's effects on behavior and what goes on in P1.","No females are present during the locomotion assay. Initially, males spent $80% of their time engaged in mating behaviors (courtship and copulation), but the percentage gradually declined to $10% over 4 hr ( Figures 1A and S1A , available online). During the assay, males mated an average of 3.3 ± 0.3 times with an average copulation duration of 24.6 ± 0.4 min that did not change with repeated matings.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/7ZzwhsZ-hFw/
10.1038/ncomms4081,Biology_568,Examples of the same can be found in patients treated for cancerous cells and tumors with radioactive material leading to permanent cell damage in some cases and painful treatment for months before the disease can be cured.,"The study thus provides a foundation for a new class of self-propelled, batch-fabricable, soft biological swimming machines.","Malignant cells like cancer cells, tumors and other toxins present inside the human anatomy can be singled out and treated without any form of damage to the rest of the body. Examples of the same can be found in patients treated for cancerous cells and tumors with radioactive material leading to permanent cell damage in some cases and painful treatment for months before the disease can be cured. With further research and development these bots can be trained to bring relief to the countless women on this planet who are struggling to conceive and have to endure months of patient wait for conceiving through methods like artificial insemination.","Although only cardiomyocytes are used as contractile cells in this work, the method is applicable to other homotypic cell types, such as optogenetic muscle cells for light-actuated swimming, or heterotypic cells types, such as turtle cardiomyocytes and fibroblasts for room temperature swimming, and neurons and muscle cells for sensing-based intelligent swimming. The study thus provides a foundation for a new class of self-propelled, batch-fabricable, soft biological swimming machines. The cross-section of the channel determines the shape of the PDMS filament.","[1.0, 1.0, 1.0, 1.0, 2.0]",Biology,train,1.2,news,http://guardianlv.com/2014/01/sperm-bots-may-make-he-man-and-chimpanzee-man-redundant-for-women/
10.1038/nature13595,Biology_569,"""We can't promise [a treatment] is going to be here today, this week, this year, or even this decade,"" said Lander.","Given the need for measures that index liability to schizophrenia , the ability to stratify individuals by RPS offers new opportunities for clinical and epidemiological research.","That and similar findings might not lead to better treatments immediately, but the researchers are confident that it will eventually. ""We can't promise [a treatment] is going to be here today, this week, this year, or even this decade,"" said Lander. ""But it's definitely going to happen.","The odds ratios increased with greater number of schizophrenia risk alleles in each sample, maximizing for the tenth decile in all samples: Denmark 7.8 (95% confidence interval (CI): 4.4-13.9), Sweden 15.0 (95% CI: 12.1-18.7) and MGS 20.3 (95% CI: 14.7-28.2). Given the need for measures that index liability to schizophrenia , the ability to stratify individuals by RPS offers new opportunities for clinical and epidemiological research. Nevertheless, we stress that the sensitivity and specificity of RPS do not support its use as a predictive test.","[1.0, 3.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.businessinsider.com/broad-institute-stanley-donation-schizophrenia-2014-7
10.1111/1365-2656.12871,Biology_57,"Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","Young rabbits, including those with maternal antibodies to either virus, had significantly lower survival rates than immune rabbits in spring (Figure 2 and Supporting Information Figure S4 ), indicating that waning protection by antibodies result in infection and potentially, mortality, later in the same year.","""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute. ""The findings suggest a continuous benefit from both viruses and maximum impact on rabbit numbers if they act together.""","Crucially, we found relatively higher survival rates of individuals susceptible to both viruses compared to those susceptible to RHDV and immune to MYXV throughout the year (Figure 2 ), indicating that rabbits immune to MYXV have a lower survival rate than susceptible individuals. Young rabbits, including those with maternal antibodies to either virus, had significantly lower survival rates than immune rabbits in spring (Figure 2 and Supporting Information Figure S4 ), indicating that waning protection by antibodies result in infection and potentially, mortality, later in the same year. Overall, monthly survival rates of those rabbits immune to both diseases were 92% (CI 90-93%; corresponding to annual survival rates of 28%-43%).","[4.0, 1.0, 4.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1098/rsbl.2013.0958,Biology_570,So a rare colour pattern can spread very rapidly until it becomes so common it attracts attention from predatory fish and starts looking like old hat to female guppies.,"22.97, all p , 0.001), rare clean-shaven (all t 548 !","In guppies, for example, males bearing rare combinations of coloured spots are both less likely to be preyed on and more likely to gain matings in the wild. So a rare colour pattern can spread very rapidly until it becomes so common it attracts attention from predatory fish and starts looking like old hat to female guppies. The selective advantages enjoyed by rare colour patterns explain why guppy colour patterns are among the most genetically variable traits yet studied.","Within treatments, beards, light and heavy stubble were more attractive than clean-shaven faces for rare beard (all t 577 ! 22.97, all p , 0.001), rare clean-shaven (all t 548 ! 7.84, all p , 0.001) and even (all t 538 !","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.healthcanal.com/life-style-fitness/49852-beards-may-be-in-but-not-for-long.html
10.1038/s41467-018-06477-7,Biology_571,"The study found the exceptional point technique to be unhelpful in a quantum setting, but the research still led to promising results.",(5) and (15) yields:,"""We think we've uncovered a new strategy for building extremely powerful quantum sensors,"" Clerk continued. The study found the exceptional point technique to be unhelpful in a quantum setting, but the research still led to promising results. ""The good news is we found another way to build a powerful new type of sensor that has advantages even in quantum regimes,"" Clerk said.","Turning to the fluctuations in the homodyne current, a straightforward calculation using Eqs. (5) and (15) yields: This extra noise corresponds to the amplification of zero-point fluctuations, and is connected to the fact that quantum mechanically, phase-insensitive linear amplification cannot be noiseless 26 .","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=37599252521&p=1pl&v=1&x=iDCnYWzxnvdZ8F2fxVrrLA
10.1038/s41467-018-03312-x,Biology_572,Disorder in the electronic states in a row of ten trapped calcium ions can disrupt the flow of energy among the ions.,"For this simple situation of only three sites and Markovian noise, all essential features of the experimentally observed power spectra are consistent with both Lindblad master equation and Bloch-Redfield calculations (see Fig.",Disorder in the electronic states in a row of ten trapped calcium ions can disrupt the flow of energy among the ions. But adding noise to the system can boost the energy flow. Disorder in the electronic states in a row of ten trapped calcium ions can disrupt the flow of energy among the ions.,"Beyond this threshold, the extracted power decreases. For this simple situation of only three sites and Markovian noise, all essential features of the experimentally observed power spectra are consistent with both Lindblad master equation and Bloch-Redfield calculations (see Fig. Integrating the measured power spectral densities S 4 (ω) and S 2 (ω) while omitting contributions from elastic (Rayleigh) scattering, we find that the total power re-emitted from the bright state into the waveguide in forward direction P 2 decreases monotonically as a function of applied noise power Φ 2 W (open purple squares in Fig.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://link.aps.org/doi/10.1103/Physics.12.13
10.1016/j.cell.2015.02.011,Biology_573,"Garcia and his colleagues show that diabodies--and by extension, EPO--activate EPO-R by variably altering the structure of the part of the receptor outside the cell.","However, dimer reorientation could be achieved by many different types of engineered scaffolds.","""This would open a new approach to therapeutics through the uniquely tailored manipulation of this medically important family of receptors."" Garcia and his colleagues show that diabodies--and by extension, EPO--activate EPO-R by variably altering the structure of the part of the receptor outside the cell. Those changes, it appears, alter the geometry of the EPO-R segment inside the cell in a manner that activates JAK2, the JAK family member associated with EPO-R. Crucially, different diabodies induce different structural changes, affecting how vigorously the JAK2s are activated.","This strategy is applicable to diseases mediated by mutated, constitutively active receptors and could offer the advantage of specificity and reduced toxicity versus broadly neutralizing kinase inhibitors. However, dimer reorientation could be achieved by many different types of engineered scaffolds. A range of altered dimerization geometries could be screened with different dimerizing scaffolds for those that induced a particular signaling profile or functional property.","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,news,http://www.sciencedaily.com/releases/2015/03/150316101907.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/nature09822,Biology_574,It's important to note that this is not a study that can be simply extrapolated to people.,"Male-male mounting (Supplementary Movie 4) was significantly higher in Tph2 2/2 males than either Tph2 1/1 or heterozygous Tph2 1/2 males: the percentage was significantly higher, duration longer, latency shorter and frequency higher ( Supplementary Fig.","The results, they concluded, suggest ""that serotonergic signaling is involved in controlling sexual preference in adult females."" It's important to note that this is not a study that can be simply extrapolated to people. There is also not much indication that human sexual preference can be pinned down to a simple neurotransmitter difference.","High-performance liquid chromatography (HPLC) analysis showed that the 5-HT level was significantly reduced in the brains of Tph2 2/2 males (Supplementary Fig. Male-male mounting (Supplementary Movie 4) was significantly higher in Tph2 2/2 males than either Tph2 1/1 or heterozygous Tph2 1/2 males: the percentage was significantly higher, duration longer, latency shorter and frequency higher ( Supplementary Fig. In the bedding preference assay, both Tph2","[2.0, 1.0, 1.0]",Biology,train,1.3333333333333333,news,http://www.medicaldaily.com/articles/16035/20130530/gay-mice-females-without-serotonin-homosexual-preference.htm
10.1186/1756-0500-4-284,Biology_575,De hecho otros estudios especifican la variedad de queso a la que los mosquitos serian devotos.,The designed trap collected a total of 59 An.,"Un estudio del cientifico Bart Knols garantiza que el aroma de pies sucios es embriagador para los mosquitos. De hecho otros estudios especifican la variedad de queso a la que los mosquitos serian devotos. Existen teorias a patadas, pero lo que esta claro es que mantener una buena higiene es basico para prevenir las picaduras.",Such traps could eventually become part of primary healthcare systems used to study the vector biology and epidemiology of mosquito-borne diseases. The designed trap collected a total of 59 An. The mean catch per day was 1.,"[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34420624379&p=1pl&v=1&x=zBKY-vPItYSpaM1fG1u43w
10.1016/j.neuron.2015.05.001,Biology_576,In a familiar environment our movements are purposeful.,A small motion artifact (dip in fluorescence) followed the initiation of locomotion.,"Furthermore, they could also help improve our understanding of movement related symptoms associated with ParkinsonaEUR(tm)s disease. In a familiar environment our movements are purposeful. aEURoeThis is a fundamental issue our brain has to deal with.","Furthermore, the slope of the rising phase of the GCaMP5 fluorescence positively correlated with the velocity of locomotion, indicating higher MSDB VGluT2 activity at higher velocities (Figure 1D) . A small motion artifact (dip in fluorescence) followed the initiation of locomotion. (F) Mean fluorescence increases in the 100 ms pre-locomotion interval compared to baseline (n = 4 mice, mean values ± SEM).","[2.0, 3.0, 2.0, 1.0, 1.0]",Biology,train,1.8,news,http://healthmedicinet.com/news/researchers-find-speedometer-in-the-brain/
10.1016/j.devcel.2016.08.005,Biology_577,"We discovered that these cells were now able to eat or otherwise remove vast quantities of redundant milk-producing cells.""",Csn gene expression epithelia preferentially switch to forming enlarged ducts rather than alveoli.,"What we didn't expect to find was a molecular switch that turned milk-secreting cells into cannibalistic cell eaters. We discovered that these cells were now able to eat or otherwise remove vast quantities of redundant milk-producing cells."" It turned out that a protein called Rac1 is central for the cellular switch.","Without Rac1, the Figure S1 . Csn gene expression epithelia preferentially switch to forming enlarged ducts rather than alveoli. Where small lobular alveolar units were present, Rac1 ablation had a severe effect on the synthesis and secretion of milk fat (Figures 2A-2C) .","[2.0, 3.0, 2.0, 2.0, 2.0]",Biology,train,2.2,news,http://healthmedicinet.com/news/post-breastfeeding-tissue-remodelling-explained-by-new-research/
10.1038/s41467-017-00525-4,Biology_578,"""We think the fact that the mitochondria become larger and elongated impairs the cell's ability to clear the damaged mitochondria,"" Walker said.","Critically, short-term, midlife induction of Drp1 improves proteostasis in aged animals.","In the new research, Walker and his colleagues found that as fruit flies reach middle age--about one month into their two-month lifespan--their mitochondria change from their original small, round shape. ""We think the fact that the mitochondria become larger and elongated impairs the cell's ability to clear the damaged mitochondria,"" Walker said. ""And our research suggests dysfunctional mitochondria accumulate with age, rather than being discarded.""","Taken together, our findings reveal that the midlife shift toward more elongated mitochondria, in flight muscle, contributes to age-onset proteotoxicity. Critically, short-term, midlife induction of Drp1 improves proteostasis in aged animals. RU486 had no significant impact on the accumulation of protein aggregates in control flies ( Supplementary Fig.","[4.0, 2.0, 1.0, 1.0]",Biology,train,1.0,news,http://healthmedicinet.com/news/biologists-slow-aging-extend-lifespan-of-fruit-flies/
10.1098/rspb.2015.2406,Biology_579,And weall be most likely to find them in the regions where plants originated.,"In the presence of rapid global change, LDD will allow species to rapidly reach suitable habitat patches and respond to changing environmental conditions, thus facilitating the persistence of many taxa under habitat fragmentation .","He says weall need plants related to our domestic familiars from which to steal survival tricks as climate changes and pests evolve. And weall be most likely to find them in the regions where plants originated. In 2009-2011, the North American growing region (which excludes Mexico) produced 443 million tons of maize.","Depending on the LDD effectiveness, migratory birds can also promote gene flow among populations distributed along bird migration routes . In the presence of rapid global change, LDD will allow species to rapidly reach suitable habitat patches and respond to changing environmental conditions, thus facilitating the persistence of many taxa under habitat fragmentation . Overall, understanding and quantifying LDD by migratory birds will be necessary to estimate the potential for range adjustment in many species, including invasive species and pathogens, that are capable of exploiting these LDD vectors.","[1.0, 1.0, 2.0, 2.0, 3.0]",Biology,train,1.8,news,http://www.nationalgeographic.com/people-and-culture/food/the-plate/2016/06/six-ways-global-local/
10.1002/emmm.201302567,Biology_58,The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA.,"We also report that the adult-SMA model-like the early-onset model-displays late-stage exacerbation of SMN2 mis-splicing, which likely accelerates disease progression.","Hence the importance of the team's success, reported online today in EMBO Molecular Medicine. The body's manufacture of the SMN protein from the SMN2 gene can limit the impact of SMA. How much a patient is helped depends on the number of copies of the SMN2 gene they possess.","In this study, we successfully generated an adult-onset SMA mouse model. Compared with early-onset SMA, adult-onset SMA may have distinct pathology, as well as therapeutic responses and requirements, potentially reflecting important differences between development and post-development. We also report that the adult-SMA model-like the early-onset model-displays late-stage exacerbation of SMN2 mis-splicing, which likely accelerates disease progression.","[2.0, 2.0, 2.0]",Biology,train,2.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1038/s41558-019-0436-6,Biology_580,"With less snow, the planet's surface will be darker and absorb more of the sun's energy.",The translation of observed X-values into predicted Y-values is not trivial.,"The snow-albedo feedback suggests the planet's declining snow coverage will amplify warming. With less snow, the planet's surface will be darker and absorb more of the sun's energy. By comparing differences in climate model predictions, scientists were able to identify which current climate variables are responsible for the greatest amount of uncertainty in the future.","When ECs are used to make predictions, care must be taken to characterise the uncertainty in the observational values of the X variable. The translation of observed X-values into predicted Y-values is not trivial. It is certainly not as simple as finding the intersection of the most likely value of observed X and the regression line relating Y to X, and 'reading off ' the predicted Y value.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=38789451352&p=1pl&v=1&x=0GHVhxVrmlfa5Rg-vhDH2w
10.1016/j.neuron.2013.04.003,Biology_582,"""All of the connections we had mapped between neurons dropped out.""","Given that VIP signaling diminishes during aging , increasingly unopposed GABAergic signaling may weaken SCN neuronal synchrony and contribute to sleep/wake cycle fragmentation in the elderly.","""We proved we had found a GABAergic network by applying drugs that block GABA receptors on the cells,"" Herzog says. ""All of the connections we had mapped between neurons dropped out."" Remarkably, when the network drops out, the clock becomes more precise.","Our data suggest that VIP may be the only agent capable of overcoming this destabilizing effect since it is only after VIP signaling is eliminated that the desynchronizing effects of GABA are unmasked. Given that VIP signaling diminishes during aging , increasingly unopposed GABAergic signaling may weaken SCN neuronal synchrony and contribute to sleep/wake cycle fragmentation in the elderly. Supplemental Information includes seven figures and Supplemental Experimental Procedures and can be found with this article online at http://dx.doi.","[1.0, 4.0, 3.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/06/130605130107.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-018-07600-4,Biology_583,"Over time, they assemble increasingly smoother sphere-shaped clusters and begin to crystallise.",This raises the fundamental question of whether some colloidal cluster sizes are thermodynamically preferred over others.,"Our three approaches are particularly closely linked in this project, underlines Prof. Engel, they complement each other and allow us to gain a deep understanding of the fundamental processes behind the forming of structures for the first time. Over time, they assemble increasingly smoother sphere-shaped clusters and begin to crystallise. It is remarkable how several thousand individual particles independently find their ideal position in a precise and highly symmetrical structure in which all particles are placed in predictable positions, explains Prof. Vogel.","While the dominant occurrence of atomic clusters with magic numbers in mass spectra 4 suggests self-adjustment in their sizes during formation by addition or removal of atoms to reach magic numbers under appropriate circumstances, the number of particles in a colloidal cluster remains fixed in confinement, which allows experiments to explore clusters of arbitrary sizes. This raises the fundamental question of whether some colloidal cluster sizes are thermodynamically preferred over others. Here, we demonstrate that the magic number phenomenon known from atomic clusters extends to the colloidal realm.","[3.0, 4.0, 3.0, 2.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=37972889807&p=1pl&v=1&x=iBPyFenSwEvA772o5rw2Og
10.1016/j.cell.2014.03.060,Biology_584,Humans are also capable of cellular regeneration to a much less impressive extent.,YAP phosphorylation by LATS1/2 results in its cytoplasmic localization and proteolytic degradation .,"This study is not the first time scientists have observed mature cells well past the believed regeneration period give rise to new cells. Humans are also capable of cellular regeneration to a much less impressive extent. So far, this cardiac regeneration was only observed in lab mice, but the team is hopeful that it can be replicated in humans in as little as five years.",The Hippo/YAP-signaling pathway is a critical regulator of liver size . YAP phosphorylation by LATS1/2 results in its cytoplasmic localization and proteolytic degradation . YAP exerts its transcriptional activity mostly by interacting with the TEAD family of transcription factors and activating target gene expression .,"[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,news,http://www.medicaldaily.com/regenerative-medicine-breakthrough-pushes-copd-treatment-forward-marks-win-method-329138
10.1111/zoj.12054,Biology_585,"After re-evaluating fossils from sites in Scotland dating to 348 million years ago, Sallan and Coates concluded that Fouldenia and its relative Styracopterus, which previous researchers had classified as the same species, are in fact separate genera.","This is contrary to the simple linear suture illustrated by and the convex suture reconstructed by , but is similar to Benedenius ; L.C.S.","The ray-finned fish really do exemplify Darwin's comment about 'endless forms most beautiful and wonderful,'"" Coates said. After re-evaluating fossils from sites in Scotland dating to 348 million years ago, Sallan and Coates concluded that Fouldenia and its relative Styracopterus, which previous researchers had classified as the same species, are in fact separate genera. Sallan and Coates determined that Fouldenia had massive tooth plates on its upper and lower jaws, suitable for preying on hard-shelled animals.","1G ) or V-shaped (NMS 1891 .53.49, NMS 1891 .53.50-51, GSE 5663, GSE 2136 ; Fig. This is contrary to the simple linear suture illustrated by and the convex suture reconstructed by , but is similar to Benedenius ; L.C.S. pers.","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130722103527.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1609221113,Biology_588,"When the researchers looked at the neurons of developing mice, they found that ones with the GPT2 mutations produced fewer synapses, the connections between neurons that make up brain circuits.","Similarly, in patient cerebrospinal fluid, decreases in alanine were seen .","For example, some of the differences undermined a process called the TCA cycle, which is important for producing energy and generating building blocks for cells. When the researchers looked at the neurons of developing mice, they found that ones with the GPT2 mutations produced fewer synapses, the connections between neurons that make up brain circuits. They found in the GPT2 mutant mice abnormal metabolite levels related to amino acid metabolism, TCA and pathways required for protecting neuron health.","GPTs serve an important role in a variety of metabolic functions, including amino acid metabolism, the urea cycle, and the TCA cycle, in addition to roles in neurotransmitter (both glutamate and GABA) synthesis. Similarly, in patient cerebrospinal fluid, decreases in alanine were seen . Interestingly, we do not see strong changes in glutamate.","[3.0, 1.0, 1.0, 1.0]",Biology,train,1.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/k6cH6Ipi5Vk/
10.1038/nature24621,Biology_59,"Within this first release of data, the Earth Microbiome Project team identified around 300,000 unique microbial 16S rRNA sequences, almost 90 percent of which don't have exact matches in pre-existing databases.","We conclude that environment specificity is best captured by individual 16S rRNA sequences, below the typical threshold defining microbial species (97% identity of the 16S rRNA gene).","That could be useful forensic information at a crime scene,"" he says. Within this first release of data, the Earth Microbiome Project team identified around 300,000 unique microbial 16S rRNA sequences, almost 90 percent of which don't have exact matches in pre-existing databases. Now, we have a framework that supports all that additional context, and which can grow organically to support new kinds of questions and insights.""","While entropy decreased gradually at finer phyloge netic resolution, it dropped sharply at the tips of the tree. We conclude that environment specificity is best captured by individual 16S rRNA sequences, below the typical threshold defining microbial species (97% identity of the 16S rRNA gene). The EMP dataset provides the ability to track individual sequences across the Earth's microbial communities.","[3.0, 2.0, 2.0]",Biology,train,2.333333333333333,news,http://www.futurity.org/earth-microbiome-project-1595972/
10.1126/scitranslmed.aau6246,Biology_590,"By refining a therapeutic avenue that was previously abandoned because of its severe side effects, they came up with a targeted approach that was both effective and safe in mice and in human cancer cells.","MRK-560 treatment significantly reduced leukemia burden compared to vehicle-treated mice, as assessed by peripheral blood counts of human CD45 + cells and in vivo bioluminescence (P ≤ 0.01) (Fig.","By refining a therapeutic avenue that was previously abandoned because of its severe side effects, they came up with a targeted approach that was both effective and safe in mice and in human cancer cells. The findings revive hope for translation to patients and have been published in this week's edition of Science Translational Medicine. ""T-ALL mainly affects children and is rapidly fatal if left untreated.","*P ≤ 0.05, ***P ≤ 0.001. MRK-560 treatment significantly reduced leukemia burden compared to vehicle-treated mice, as assessed by peripheral blood counts of human CD45 + cells and in vivo bioluminescence (P ≤ 0.01) (Fig. The various degrees of response to MRK-560 treatment were not explained by differences in PSEN1 expression in the PDX models ( fig.","[2.0, 5.0, 2.0]",Biology,train,3.0,news,http://ct.moreover.com/?a=39346780506&p=1pl&v=1&x=IKfPODs-6ywejyqBclqdIw
10.1016/j.cell.2015.06.045,Biology_591,"""When this child's mutation was introduced into an animal model, we saw all these dendritic spines form on the neurons,"" said, Zylka, who is also a member of the Carolina Institute for Developmental Disabilities.","We found that the T485A mutant accelerated the formation of S5a ubiquitin conjugates as compared to WT UBE3A, whereas the UBE3A T485E mutant behaved like the ligase-dead UBE3A mutant ( Figure 4G ).","The child's regulatory switch was broken, causing UBE3A to be perpetually switched on. ""When this child's mutation was introduced into an animal model, we saw all these dendritic spines form on the neurons,"" said, Zylka, who is also a member of the Carolina Institute for Developmental Disabilities. Their findings thus pointed to hyperactivation of UBE3A as the likely cause of this child's autism.","Unlike the T485A mutation, none of these additional phosphorylation site mutations altered UBE3A levels ( Figures  S3F and S3G ), suggesting that T485 is the principal site for posttranslational regulation in this region. We found that the T485A mutant accelerated the formation of S5a ubiquitin conjugates as compared to WT UBE3A, whereas the UBE3A T485E mutant behaved like the ligase-dead UBE3A mutant ( Figure 4G ). Consistent with our in vitro assays, the T485A mutant was hyperactive, generating more HHR23A-ubiquitin conjugates relative to WT UBE3A, whereas UBE3A-T485E did not ubiquitinate HHR23A ( Figure 4H) .","[2.0, 2.0, 2.0, 3.0]",Biology,train,2.25,news,http://www.healthcanal.com/alternative-therapies/65935-unc-scientists-pinpoint-how-a-single-genetic-mutation-causes-autism.html
10.1016/j.ebiom.2017.11.032,Biology_594,Professor Cook said developing a reliable means of predicting epileptic seizures for individual patients was an incredibly complex area of research.,This holds equally true for the algorithm described in .,"""The hope is that one day this research could help inform the development of assistive technologies that could not only warn people with epilepsy of imminent seizures, but constantly adapt to how their brains change over time."" Professor Cook said developing a reliable means of predicting epileptic seizures for individual patients was an incredibly complex area of research. ""This is in large part due to how epilepsy manifests itself uniquely in each patient, as well as individual long-term changes in brain signals,"" said Professor Cook.","showed that seizure prediction is possible using feature engineering techniques , the primary criticisms of their world-first, long-term study was varying prediction performance across patients and a lack of tunability to accommodate patient preferences . This holds equally true for the algorithm described in . On the other hand, the system presented in had the ability to forecast not only imminent seizures, but also times of low seizure likelihood for some patients.","[1.0, 4.0, 1.0]",Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/zNFpbZqMOBc/
10.1038/s41467-018-04251-3,Biology_595,"To make use of the new coating, a laser is needed.",The EP degeneracy featured by zero scattering eigenvalue splitting is designed at 632.8 nm by optimizing the respective thicknesses of Au and PMMA layers.,"The coating, which significantly enhances the slide's sensitivity to light detection, would be added to slides during the manufacturing process. To make use of the new coating, a laser is needed. Zhao says a common helium-neon laser, which can be seamlessly integrated with most microscopes, will do the job.",Spatially resolved thermal mapping. The EP degeneracy featured by zero scattering eigenvalue splitting is designed at 632.8 nm by optimizing the respective thicknesses of Au and PMMA layers. The abrupt EP phase transition can be fully characterized by the quasi-linear response of forward reflection with almost negligible differences.,"[2.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.2,news,http://ct.moreover.com/?a=33951949529&p=1pl&v=1&x=e8y7ustjAAUaGuSvcP0nKg
10.1016/j.neuron.2013.08.029,Biology_596,"The amygdala neurons appeared normal from an electrical point of view, and the whole- face-sensitive neurons responded normally.","If the subject did not respond by that time, a timeout was indicated by a beep (2.2% of all trials were timeouts and were excluded from analysis; there was no difference in timeouts between ASD patients and controls).","""A subpopulation of neurons in these patients with autism spectrum disorder showed abnormal sensitivity to the mouth region. The amygdala neurons appeared normal from an electrical point of view, and the whole- face-sensitive neurons responded normally. Thus, the subset of face-part-sensitive neurons was specifically abnormal in autism,"" Rutishauser said.","They thus had the same amplitude spectrum and average luminance. If the subject did not respond by that time, a timeout was indicated by a beep (2.2% of all trials were timeouts and were excluded from analysis; there was no difference in timeouts between ASD patients and controls). Pixels with high positive correlation indicate that revealing this pixel increases task performance.","[1.0, 1.0, 2.0]",Biology,train,1.3333333333333333,news,http://www.newswise.com/articles/neurons-in-brain-s-face-recognition-center-respond-differently-in-patients-with-autism
10.1007/s12263-009-0145-2,Biology_597,"The effect was even more potent when these diet-induced obese mice (DIO) were treated daily for four days: Their incretin levels increased 10-fold, while their fasting blood sugar plummeted and insulin sensitivity improved.",Resveratrol exists in cis and trans isomeric forms.,"Researchers found that in mice who got fat from overeating, treatment with KDT501 before a meal caused them to clear glucose from their blood significantly faster than untreated control mice. The effect was even more potent when these diet-induced obese mice (DIO) were treated daily for four days: Their incretin levels increased 10-fold, while their fasting blood sugar plummeted and insulin sensitivity improved. When they treated DIO mice with both molecules, the mice produced even higher levels of incretins than with either the DPP-IV inhibitor or KDT501 alone.","Resveratrol exists in cis and trans isomeric forms. The most important point about resveratrol is that at a particular range of concentration, it inhibits apoptotic cell death, thereby providing protection from various diseases including myocardial ischemic reperfusion injury, atherosclerosis, ventricular arrhythmias, and cerebral ischemia . The same resveratrol when used in higher doses facilitates apoptotic cell death, behaving in contrast as a chemo-preventive agent .","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,news,http://ct.moreover.com/?a=38681835156&p=1pl&v=1&x=xXDTZPEFlwmrJYBXe63Rlg
10.1038/s41598-019-42251-5,Biology_598,"You know the seeds are there, but they're hiding,"" he said.","E-Cadherin expressing NCI-H522 cells exhibited an epithelial growth pattern in vitro, unlike the parental cells, which showed less cell-cell contact (Fig.","Those cancer stem cells, Taylor said, are similar to dandelions in a well-manicured lawn. You know the seeds are there, but they're hiding,"" he said. Cancers can be like this as well.""","Sensitivity to paclitaxel, etoposide, imatinib and gefitinib did not correlate with vimentin expression (Fig. E-Cadherin expressing NCI-H522 cells exhibited an epithelial growth pattern in vitro, unlike the parental cells, which showed less cell-cell contact (Fig. Exposure of reconstituted cells to either U0126 or 4 did not affect expression of exogenous E-cadherin (Fig.","[1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=39648992542&p=1pl&v=1&x=Z_STrOemJeL57Svz8NHfKQ
10.1038/s41467-019-09348-x,Biology_599,"It was an incredibly good guess, one that remains solid in the face of time and experiment, and is now a fundamental principle in quantum mechanics.","The reversible transformations (for example, possible time evolutions) of pure states of C d are the unitary transformations ψ → U ψ with U ∈ U(d).","It was an incredibly good guess, one that remains solid in the face of time and experiment, and is now a fundamental principle in quantum mechanics. But a bold new attempt to rewrite it could be the break we've been looking for to finally understand it in full. They're not the first to look for deeper truths to this most mind-boggling of quantum principles.","This notation is justified, since all countably infinite-dimensional Hilbert spaces are isomorphic [32] . The reversible transformations (for example, possible time evolutions) of pure states of C d are the unitary transformations ψ → U ψ with U ∈ U(d). The joint pure states of systems C a and C b are the rays of the tensor-product Hilbert space C a ⊗ C b .","[2.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.2,news,http://ct.moreover.com/?a=38677089503&p=1pl&v=1&x=xYxE2q0X5zuFs01gWNCmoA
10.1210/en.2015-2036,Biology_6,"In mice, vitamin D signaling inhibited the expression of ID1.","We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) .","In mice, vitamin D signaling inhibited the expression of ID1. When these mice were deficient in serum vitamin D, due to a vitamin-D-deficient diet, ID1 expression was no longer suppressed. These results suggested that vitamin D deficiency acts in a cell autonomous manner, rather than systematically, to affect breast cancer.","This 'hit' was of particular interest because of the role of Id1 in BCa progression and most intriguing because calcitriol was found to induce, rather than repress, ID1 expression in a colon carcinoma cell line . We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) . To test whether the regulation of Id1 by VDR is ligand dependent in BCa cells, we treated 168FARN cells with calcitriol and showed that this treatment represses the expression of Id1 ( Figure 3C ).","[3.0, 2.0, 2.0]",Biology,train,2.333333333333333,news,http://www.oncologynurseadvisor.com/lack-of-vitamin-d-may-encourage-breast-cancer-metastasis/article/485433/
10.1073/pnas.1504869112,Biology_60,The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death.,"The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests.","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Liana-tree competition can be far more intense than tree-tree competition (3), substantially reducing tree growth , fecundity , and survival . The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .","[2.0, 2.0, 2.0, 4.0]",Biology,train,2.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1126/scitranslmed.3009759,Biology_601,"It could be that taking antibiotics at the wrong time during pregnancy is creating abnormalities in the blood-brain barrier of the child, she says.","The increased permeability of the BBB in germ-free adult mice may partly be the consequence of disorganized tight junctions, as shown by electron microscopy analysis, and low expression of the transmembrane tight junction proteins occludin and claudin-5.","But at the very least, the findings point toward a new understanding of human health and disease, says Lora Hooper, an immunologist at the University of Texas Southwestern Medical Center in Dallas who was not involved in the work. Scientists, Hooper adds, should also investigate whether microbes help spur the development of the human fetus's blood-brain barrier. It could be that taking antibiotics at the wrong time during pregnancy is creating abnormalities in the blood-brain barrier of the child, she says.","Furthermore, our data show that a more permeable BBB is observed in the fetal mice with germ-free mothers at E16.5 to E18.5 days of embryonic development compared to the fetal mice with pathogenfree mothers at the same stages of development. The increased permeability of the BBB in germ-free adult mice may partly be the consequence of disorganized tight junctions, as shown by electron microscopy analysis, and low expression of the transmembrane tight junction proteins occludin and claudin-5. The ""conventionalization"" of germ-free adult mice through transplant of the fecal microbiota from pathogen-free adult mice or by administering bacterial strains that produce SCFAs reinforced the integrity of the mouse BBB.","[1.0, 4.0, 1.0, 2.0]",Biology,train,2.0,news,http://news.sciencemag.org/biology/2014/11/bodys-bacteria-may-keep-our-brains-healthy
10.1016/j.ntt.2014.11.002,Biology_603,"""If we can find these health problems early on in preclinical testing, it has the potential of saving them a lot of money,"" Potts says.","No effect of time (GLMM; z = −0.70, p = 0.49) or time by treatment was detected (GLMM; z = 0.65, p = 0.52).","The study will be published in the January-February issue of Neurotoxicology and Teratology, which has posted a preprint online. ""If we can find these health problems early on in preclinical testing, it has the potential of saving them a lot of money,"" Potts says. Laboratory mice that are only slightly less healthy may not appear so when given ample food and living space.","Control breeders produced an average of 4.54 (SEM +0.45, − 0.41) pups in their first litter, while paroxetine-exposed breeders produced 4.09 (+ 0.83, − 0.75) pups in their first litter. No effect of time (GLMM; z = −0.70, p = 0.49) or time by treatment was detected (GLMM; z = 0.65, p = 0.52). Offspring from paroxetine-exposed breeders weighed less at weaning than offspring from control breeders.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141215094147.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/sciadv.aat4505,Biology_604,"Now, Waters may have found such a style.","Since burial, these zones have remained intact with minimal disturbance.","Worse still, they had no way of consistently identifying pre-Clovis stone tools, which--unlike the easy-to-recognize Clovis points--didn't seem to have a unified style. Now, Waters may have found such a style. Waters's team uncovered 11 western stemmed points in a layer of sediment about 15 centimeters below the earliest Clovis points at the site, meaning they are almost certainly older.","This shows that there were sequential occupations on the Buttermilk Creek floodplain that were incrementally buried over time by sediment during repeated overbank events over the last 13 ka. Since burial, these zones have remained intact with minimal disturbance. At the Friedkin site, these point styles are generally in chronostratigraphic order, with two Andice points occurring with two Wells points near the top of this zone, two Baird points below these, and eight Angostura points in the lowest portion of the Middle Archaic and Early Archaic zone.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=37487404064&p=1pl&v=1&x=Xu4_ceCprmz50ykSJe_jOg
10.1098/rstb.2017.0259,Biology_606,"And in 4 percent of the cases, these encounters turned sexual.","If crows exhibit a danger response, we expect higher rates of alarm calling and recruitment coupled with lower rates of contact in contrast to heterospecifics.","But in 24 percent of the cases, something overwhelmed those instincts and the birds would touch, pull, drag, or peck at the corpses. And in 4 percent of the cases, these encounters turned sexual. ""In the most dramatic examples, a crow would approach the dead crow while alarm calling, copulate with it, be joined in the sexual frenzy by its presumed mate, and then rip it into absolute shreds,"" Swift wrote.","If such information acquisition motivates tactile interactions, we expect that interactions will be coupled with alarm calling and recruitment, be primarily non-aggressive in nature and occur frequently and uniformly across the study period. If crows exhibit a danger response, we expect higher rates of alarm calling and recruitment coupled with lower rates of contact in contrast to heterospecifics. We expect that the life-like crow will result in scolding and divebombing, but infrequent recruitment, and that contact will be primarily aggressive.","[3.0, 2.0, 1.0, 1.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=34585550159&p=1pl&v=1&x=WyV3BKDktHbHhzNbbBgu3Q
10.1016/j.resmic.2008.06.001,Biology_607,And five gray is fatal to a human being.,"Three additional opportunistic pathogens, A. terreus, Fusarium solani, and Candida albicans, were not detected in the dust (data not given).","Half a gray, delivered in one blast, is enough to give a person radiation sickness. And five gray is fatal to a human being. The spores also survived 3,000 joules per metre squared of the ultraviolet radiation.","Of the 36 species in the standard ERMI analysis, 17 were detected at some concentration. Three additional opportunistic pathogens, A. terreus, Fusarium solani, and Candida albicans, were not detected in the dust (data not given). This approach gave the crew an estimate of the number of viable microbes relatively quickly (depending on microbial growth rate).","[1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=39566649444&p=1pl&v=1&x=k13F-OtaawvZF0Lci2zbqg
10.1089/nat.2018.0772,Biology_608,This thoughtful set of guidelines has now been endorsed by both the board of the Oligonucleotide Therapeutic Society and the editorial board of Nucleic Acid Therapeutics.,Researchers should take the responsibility of being their own greatest skeptic.,"This thoughtful set of guidelines has now been endorsed by both the board of the Oligonucleotide Therapeutic Society and the editorial board of Nucleic Acid Therapeutics. This paper reinforces our continuing commitment to improving experimental design and we encourage submission of further commentaries that share this goal,"" says Executive Editor Graham C. Parker, PhD, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, MI.","Regardless of the exact nature of the application, the burden is on editors, reviewers, and readers to demand that this information be supplied. Researchers should take the responsibility of being their own greatest skeptic. They should clearly describe the experimental evidence that leads them to conclude that observed effects are likely due to the engagement of their synthetic oligonucleotide with the intended, complementary target sequence.","[4.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=38920544801&p=1pl&v=1&x=JbRzmeZCPkZGV_xJefDymw
10.1111/ele.12889,Biology_609,Millions of Canadians inhaled poor-quality air for weeks.,"The proportion of dry forest sites with seedling densities exceeding recruitment thresholds was also lower after 21st-century wildfires, declining from 49% (in sites that burned prior to 2000) to 30% (in sites burned since 2000; v 2 = 14.3, P = 0.0002).",The asthma-aggravating smoke travelled hundreds of kilometres across the Prairies. Millions of Canadians inhaled poor-quality air for weeks. And we're still adding new charges to our bill.,"2, v 2 = 8.5, P = 0.004). The proportion of dry forest sites with seedling densities exceeding recruitment thresholds was also lower after 21st-century wildfires, declining from 49% (in sites that burned prior to 2000) to 30% (in sites burned since 2000; v 2 = 14.3, P = 0.0002). Moist forest types exhibited a similar decline in regeneration (v 2 > 7.5, P < 0.01), but the proportion of sites with seedlings or densities exceeding recruitment thresholds was greater than 65% in both time periods, declining from 91 to 65%.","[3.0, 1.0, 1.0]",Biology,train,1.6666666666666667,news,http://ct.moreover.com/?a=39580911059&p=1pl&v=1&x=IuvihixhWX9v9GXWblNagQ
10.3945/jn.113.188441,Biology_61,"In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap.","The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","He said that can likely be attributed to biological differences (such as sex hormones and metabolism) between the sexes, as well as obesity and metabolic syndrome components. In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap. Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies.","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age. Our study had several limitations.","[4.0, 1.0, 1.0, 1.0]",Biology,train,1.0,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1073/pnas.1504869112,Biology_62,The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death.,These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .,"The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( . Nonetheless, these initial studies indicate that increasing liana abundance may alter the carbon balance and cycle of tropical forests by reducing forestlevel carbon storage and sequestration.","[5.0, 2.0, 3.0, 4.0, 2.0]",Biology,train,3.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.3945/jn.113.188441,Biology_63,"In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap.","The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome (OR: 1.68; 95% CI: 1.10, 2.55) in women but not in men (OR: 0.93; 95% CI: 0.58, 1.49; P-interaction = 0.04).","He said that can likely be attributed to biological differences (such as sex hormones and metabolism) between the sexes, as well as obesity and metabolic syndrome components. In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap. Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies.","The highest quintile for the TP was associated with decreased prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06), but neither of the dietary patterns was associated with prevalence of metabolic syndrome. The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome (OR: 1.68; 95% CI: 1.10, 2.55) in women but not in men (OR: 0.93; 95% CI: 0.58, 1.49; P-interaction = 0.04). The 2 major dietary patterns were associated with distinct cardiometabolic risk factors.","[4.0, 1.0, 1.0, 4.0, 2.0]",Biology,train,2.0,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.14814/phy2.13617,Biology_64,Melatonin levels were 88 percent lower after bright light exposure.,"Melatonin levels at 10-min (P = 0.008, d = 0.70), 30-min (P = 0.006, d = 1.56), and 50-min after the start of the light exposure (P = 0.002, d = 1.86) were significantly lower than levels at the same clock times in the dim light condition (Fig.","""In this study we found that these kids were extremely sensitive to light."" Melatonin levels were 88 percent lower after bright light exposure. Levels remained suppressed at least 50 minutes after the light was shut off.","Average melatonin suppression across the light exposure was 87.6 AE 10. and at the same relative clock times during the dim light condition (AUC DL ) are plotted for each subject in Figure 2 . Melatonin levels at 10-min (P = 0.008, d = 0.70), 30-min (P = 0.006, d = 1.56), and 50-min after the start of the light exposure (P = 0.002, d = 1.86) were significantly lower than levels at the same clock times in the dim light condition (Fig. Melatonin levels remained significantly lower at 20-min (P < 0.001, d = 2.07) and 50-min following the end of the bright light exposure condition (P < 0.001, d = 1.43) compared to the dim light condition (Fig.","[5.0, 4.0, 2.0, 5.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=33480456707&p=1pl&v=1&x=hN9hUXXld--gBVhWbWCNfA
10.1007/s10336-017-1477-0,Biology_67,"In the end, the Liberian and icterine greenbuls turned out to share an astonishing amount of genetic similarities, much more than any other two species of greenbul.","Although the Liberian Greenbul specimen was only 33 years old, none of the above primers produced bands from that sample, consistent with significant DNA degradation.","According to the data, the most likely explanation for a lack of new Liberian greenbuls is the fact that they don't actually exist. In the end, the Liberian and icterine greenbuls turned out to share an astonishing amount of genetic similarities, much more than any other two species of greenbul. ""We can't say definitively that the Liberian greenbul is the same bird as the icterine greenbul, but we have presented enough evidence that makes any other explanation seem highly unlikely.""","Isolation of Liberian Greenbul DNA and initial PCRs were performed The most obvious feature that distinguishes it from the otherwise very similar Icterine Greenbul P. icterinus is the presence of white subterminal 'eye spots' to the wing feathers-a feature not shown by any other species of Phyllastrephus. Although the Liberian Greenbul specimen was only 33 years old, none of the above primers produced bands from that sample, consistent with significant DNA degradation. The Liberian Greenbul sequence was identical to that from one of the Icterine Greenbuls ('MAR6611') sampled in Liberia.","[4.0, 1.0, 2.0]",Biology,train,1.0,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1016/j.mito.2018.08.001,Biology_68,"A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first.","If a new head injury is sustained before complete healing of an earlier concussion, the clinical severity of the second injury is amplified, and recovery is prolonged.","The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego. A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first. When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors.","If healing is incomplete between injuries, more severe disease is produced. If a new head injury is sustained before complete healing of an earlier concussion, the clinical severity of the second injury is amplified, and recovery is prolonged. This occurs even when the energy of the second impact was less than the first.","[5.0, 4.0, 5.0, 5.0, 5.0]",Biology,train,4.8,news,http://ct.moreover.com/?a=37052707703&p=1pl&v=1&x=sh4bblHfq4G8CThdM37YaA
10.14814/phy2.13617,Biology_69,"""We hope this research can help parents and clinicians make informed decisions on children's light exposure.""",Findings from this study indicated that school-age children were almost twice as sensitive to the melatonin suppression effects of evening moderate bright light exposure (~580 lux) than their parents .,"The study sample size was small and it used only one intensity of light, 1,000 lux, which is far greater than the intensity of a typical handheld electronic device, she notes. ""We hope this research can help parents and clinicians make informed decisions on children's light exposure."" The takeaway for parents today: Dim the lights in the hours before bedtime.","Findings from this study mark an important step in addressing a gap in understanding the melatonin suppression response across the lifespan. Findings from this study indicated that school-age children were almost twice as sensitive to the melatonin suppression effects of evening moderate bright light exposure (~580 lux) than their parents . Additionally, based upon an objective measure of pubertal development ), Crowley and colleagues found that that prepubertal adolescents (Tanner stage 1-3) were more sensitive to the suppressive effects of evening light on melatonin than postpubertal adolescents (Tanner stage 4-5) .","[2.0, 1.0, 2.0, 2.0]",Biology,train,1.75,news,http://healthmedicinet.com/news/preschoolers-exposed-to-nighttime-light-lack-melatonin/
10.1210/en.2015-2036,Biology_7,"In mice, vitamin D signaling inhibited the expression of ID1.",These results indicate that the relationship between Id1 expression and vitamin D status/VDR signaling that we identified in our mouse studies is conserved in humans and is relevant to patients with BCa.,"In mice, vitamin D signaling inhibited the expression of ID1. When these mice were deficient in serum vitamin D, due to a vitamin-D-deficient diet, ID1 expression was no longer suppressed. These results suggested that vitamin D deficiency acts in a cell autonomous manner, rather than systematically, to affect breast cancer.","We found that serum 25(OH)D levels at the time of surgery were negatively associated with ID1 expression levels in the corresponding tumors (Spearman correlation coefficient r ϭ Ϫ0.579, P Ͻ .001), with every 10-ng increase in circulating 25(OH)D levels being associated with a 20% reduction in ID1 expression levels in the tumor ( Figure 4D ). These results indicate that the relationship between Id1 expression and vitamin D status/VDR signaling that we identified in our mouse studies is conserved in humans and is relevant to patients with BCa. Our results show that dietary vitamin D deficiency accelerates the growth of BCa tumors.","[2.0, 2.0, 4.0]",Biology,train,2.6666666666666665,news,http://www.oncologynurseadvisor.com/lack-of-vitamin-d-may-encourage-breast-cancer-metastasis/article/485433/
10.14814/phy2.13617,Biology_70,"""We hope this research can help parents and clinicians make informed decisions on children's light exposure.""","A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children.","The study sample size was small and it used only one intensity of light, 1,000 lux, which is far greater than the intensity of a typical handheld electronic device, she notes. ""We hope this research can help parents and clinicians make informed decisions on children's light exposure."" The takeaway for parents today: Dim the lights in the hours before bedtime.","To our knowledge, this study is the first to quantify the melatonin suppression response to evening light exposure in healthy 3-to 5-year-old children. A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children. Findings from this study mark an important step in addressing a gap in understanding the melatonin suppression response across the lifespan.","[2.0, 3.0, 1.0, 3.0, 4.0]",Biology,train,2.6,news,http://healthmedicinet.com/news/preschoolers-exposed-to-nighttime-light-lack-melatonin/
10.1126/sciadv.aat5107,Biology_71,"The BioBits kits enable us to expose young kids, older kids, and even adults to the wonders of synthetic biology and, as a result, are poised to transform science education and society.",We anticipate that the availability of our BioBits™ kits and the data reported here will encourage teaching and broaden participation in the field of synthetic biology.,"""We show that it is possible to use freeze-dried, cell-free extracts along with freeze-dried synthetic biology components to conduct innovative educational experiments in classrooms and other low-resource settings. The BioBits kits enable us to expose young kids, older kids, and even adults to the wonders of synthetic biology and, as a result, are poised to transform science education and society. This BioBits project demonstrates the kind of out-of-the-box thinking and refusal to accept the status quo that we value and cultivate at the Wyss Institute, and we all hope it will stimulate young people to be intrigued by science,"" said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School (HMS) and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at Harvard's John A. Paulson School of Engineering and Applied Sciences (SEAS).","Titrating the amount of DNA template results in varying levels of fluorescent protein production, which are visible to the naked eye and under a blue or black light. We anticipate that the availability of our BioBits™ kits and the data reported here will encourage teaching and broaden participation in the field of synthetic biology. We observed that all proteins expressed with high soluble yields (between 160 and >1100 g ml −1 ) ( Fig.","[3.0, 3.0, 5.0]",Biology,train,3.6666666666666665,news,http://ct.moreover.com/?a=34696777548&p=1pl&v=1&x=pxhPjHWCPi8TfA-LxM_Vbw
10.1016/j.cell.2018.04.034,Biology_73,"""The Prostate Cancer Foundation is proud to have funded this team, which continues to make foundational strides in identifying actionable genomic mutations in prostate cancer and using this information to identify new classes of precision treatments that can be used to improve the lives of men with prostate cancer.""",CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion.,"More study is needed to understand this. ""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation. ""The Prostate Cancer Foundation is proud to have funded this team, which continues to make foundational strides in identifying actionable genomic mutations in prostate cancer and using this information to identify new classes of precision treatments that can be used to improve the lives of men with prostate cancer.""",CDK12 mutant cases are baseline diploid and do not exhibit DNA mutational signatures linked to defects in homologous recombination. CDK12 mutant cases are associated with elevated neoantigen burden ensuing from fusion-induced chimeric open reading frames and increased tumor T cell infiltration/clonal expansion. FTDs associated with CDK12 loss result in highly recurrent gains at loci of genes involved in the cell cycle and DNA replication.,"[2.0, 1.0, 1.0, 3.0, 2.0]",Biology,train,1.8,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1016/j.cell.2013.08.004,Biology_74,These drugs also might have broader therapeutic value for patients with mental health issues.,"As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing.","The findings reveal a little bit more about how our internal clocks function. In addition, the research could pave the way for drugs that could bring bodies in tune with the solar cycle more quickly. These drugs also might have broader therapeutic value for patients with mental health issues.","Critically, we show that knockdown of Sik1 within the SCN results in extended light-induced phase shifts and an enhanced rate of re-entrainment to an advanced LD cycle. As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing. Surprisingly, the majority (81%, 436 genes) of transcripts were downregulated in response to light, with a smaller number of genes showing upregulation (19%, 100 genes).","[3.0, 1.0, 1.0, 2.0]",Biology,train,1.75,news,http://www.scienceworldreport.com/articles/9204/20130902/what-causes-jet-lag-internal-clock-slow-change-time.htm
10.1186/gb-2013-14-7-r73,Biology_76,The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues.,"Of 2,285 vlincRNAs found in cancerous or immortalized cells/tissues, 1,088 (47.7%) occurred in the non-cancerous cell lines or blood.","""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics."" The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues. Researchers found that some of these vlincRNAs are co-opted by cancer-associated transcriptional programs.","A complex normal human tissue, blood, revealed expression of 613 vlincRNAs, of which 331 (p-value 2.03 × 10 -49 ) overlap ENCODE vlincRNAs. Of 2,285 vlincRNAs found in cancerous or immortalized cells/tissues, 1,088 (47.7%) occurred in the non-cancerous cell lines or blood. While cancerous cells have highlyrearranged genomes and, in theory, could produce non-functional vlincRNA transcripts that reflect those re-arrangements, this argument cannot be made about the Figure S1 .","[5.0, 4.0, 4.0, 4.0]",Biology,train,4.25,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.cell.2013.08.004,Biology_77,"Overall, the researchers found that the SIK1 protein delays the body clock's shifting response to time changes, and therefore causes complications for travelers and shift workers.","As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing.","""The study proposes that the light-stimulated production of SIK1 in turn switches off the molecular pathway that feeds into the clock mechanism, thereby halting the shifting response of the biological clock,"" the researchers wrote. Overall, the researchers found that the SIK1 protein delays the body clock's shifting response to time changes, and therefore causes complications for travelers and shift workers. ""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and working as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules,"" said Duffield.","Critically, we show that knockdown of Sik1 within the SCN results in extended light-induced phase shifts and an enhanced rate of re-entrainment to an advanced LD cycle. As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing. Surprisingly, the majority (81%, 436 genes) of transcripts were downregulated in response to light, with a smaller number of genes showing upregulation (19%, 100 genes).","[3.0, 5.0, 4.0, 4.0, 3.0]",Biology,train,3.8,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1007/s10336-017-1477-0,Biology_78,"And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage.",That the Liberian Greenbul was heterozyogous at none of these positions strongly suggests that it was not an Icterine 9 Spotted Greenbul hybrid.,"""We can't say definitively that the Liberian greenbul is the same bird as the icterine greenbul, but we have presented enough evidence that makes any other explanation seem highly unlikely."" And it's not like the purported new species was even a hybrid - analysis also excluded that probability, leaving the researchers to hypothesise that the 'Liberian' greenbul was just an icterine greenbul with a juvenile nutritional deficiency that caused changes to its plumage. But despite the thorough genetic analysis and unlikely alternative explanations, we can't yet say that the elusive birds absolutely, definitely don't exist - it looks like once something becomes a species, unspecying it is a tougher ask.","In contrast, there were 9 single-bp changes and a 2-bp indel between Icterine/Liberian Greenbul sequences and that of Spotted Greenbul. That the Liberian Greenbul was heterozyogous at none of these positions strongly suggests that it was not an Icterine 9 Spotted Greenbul hybrid. The current study has failed to find any significant genetic distance between Icterine and Liberian Greenbuls, whilst demonstrating large and diagnostic genetic distances between other species of greenbul in the genus Phyllastrephus.","[4.0, 4.0, 1.0, 4.0]",Biology,train,4.0,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1038/s41467-018-05870-6,Biology_8,"""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases.""","These Ago2-mediated molecular events may solve the paradox of protein biosynthesis in the obese liver, demonstrate a new mechanism in the regulation of basal metabolic activity, and provide a novel therapeutic target for metabolic diseases.","""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology. ""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases."" Novel Science

The scientists caution the research is early stage.","This condition can amplify activation of AMPK and its substrates ULK1, MFF, and Pgc1α, leading to improved mitochondrial capacity and quality, which in turn generates sufficient energy for protein biosynthesis. These Ago2-mediated molecular events may solve the paradox of protein biosynthesis in the obese liver, demonstrate a new mechanism in the regulation of basal metabolic activity, and provide a novel therapeutic target for metabolic diseases. In conclusion, our results highlight that Ago2 uniquely regulates energy production and consumption in the liver, and suggest hepatic Ago2-mediated RNA silencing is a key regulator of glucose and lipid metabolism during the pathogenesis of obesity.","[4.0, 3.0, 4.0, 4.0]",Biology,train,3.75,news,http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A
10.1126/sciadv.aat5107,Biology_80,"The BioBits kits enable us to expose young kids, older kids, and even adults to the wonders of synthetic biology and, as a result, are poised to transform science education and society.","In sum, BioBits™ Bright represents a comprehensive set of educational resources for synthetic biology akin to the ""chemistry set"" that brought chemistry education to the masses and inspired generations of scientists.","""We show that it is possible to use freeze-dried, cell-free extracts along with freeze-dried synthetic biology components to conduct innovative educational experiments in classrooms and other low-resource settings. The BioBits kits enable us to expose young kids, older kids, and even adults to the wonders of synthetic biology and, as a result, are poised to transform science education and society. This BioBits project demonstrates the kind of out-of-the-box thinking and refusal to accept the status quo that we value and cultivate at the Wyss Institute, and we all hope it will stimulate young people to be intrigued by science,"" said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School (HMS) and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at Harvard's John A. Paulson School of Engineering and Applied Sciences (SEAS).","We also plan to launch a website where students can share their data and biological program designs with other users of these kits from around the world. In sum, BioBits™ Bright represents a comprehensive set of educational resources for synthetic biology akin to the ""chemistry set"" that brought chemistry education to the masses and inspired generations of scientists. This is made possible by our in-house freeze-dried reactions, which are two orders of magnitude more affordable than existing commercial cell-free kits, at just ~US$0.01 per microliter of reaction volume (table S3) compared to ~US$1 per microliter (Promega L110; NEB E6800S).","[3.0, 4.0, 3.0]",Biology,train,3.333333333333333,news,http://ct.moreover.com/?a=34696777548&p=1pl&v=1&x=pxhPjHWCPi8TfA-LxM_Vbw
10.1016/j.cell.2013.08.004,Biology_82,"Dr. Russell Foster said that we were still a long way off from a jet lag cure, but added it was a step towards developing drugs for interrupted sleep cycles.",Sik1 silenced mice showed significantly faster re-entrainment when compared to the controls in both cycles ( Figure 5C ).,"When they blocked the activity of SIK1, the mice adjusted faster to changes in light cycle. Dr. Russell Foster said that we were still a long way off from a jet lag cure, but added it was a step towards developing drugs for interrupted sleep cycles. ""Such drugs could potentially have broader therapeutic value for people with mental health issues.""","Compared with the controls, the mice with Sik1 silenced showed significantly enhanced phase shifts (98 min compared to 50 min, p = 0.036, Figure 5B ). Sik1 silenced mice showed significantly faster re-entrainment when compared to the controls in both cycles ( Figure 5C ). To illustrate the magnitude of this effect, on day 2 the difference in phase was over 3 hr in the siNT-injected animals but was less than 1 hr in the Sik1-silenced mice ( Figure 5D ).","[1.0, 1.0, 1.0, 2.0]",Biology,train,1.25,news,http://www.businessinsider.com/cure-for-jet-lag-2013-8
10.1073/pnas.1504869112,Biology_83,"Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more.","Likewise, a potential liana-driven shift in tree species composition may also alter long-term biomass carbon storage if the presence of lianas leads to an increase in fast-growing trees with low wood densities, as is predicted .","The researchers found that study plots with lianas accumulated 76 percent less biomass over the experimental period due to reduced tree growth and increased tree death. Extrapolating their results to tropical forests as a whole, the team calculated that lianas could potentially reduce long-term storage of carbon in tropical forests by one-third or more. The study will be useful in guiding scientists working to predict the trajectory of carbon storage as atmospheric concentrations rise, and it may help explain recent observations that the carbon storage capacity of tropical forests is declining.","Long-term Submission PDF biomass carbon storage may be further reduced if increasing liana biomass intensifies liana-tree competition and/or increases the proportion of trees that are competing with lianas. Likewise, a potential liana-driven shift in tree species composition may also alter long-term biomass carbon storage if the presence of lianas leads to an increase in fast-growing trees with low wood densities, as is predicted . Nevertheless, our simulation provides an initial conservative estimate of the potential long-term effect of lianas on forest-level carbon stocks.","[4.0, 3.0, 3.0, 4.0, 4.0]",Biology,train,3.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/PUyOGba13Ho/
10.1111/gcb.13276,Biology_87,"Based on a massive amount of historical data, the index can be used to compare the bleaching responses of corals throughout the world and to predict which corals may be most affected by future bleaching events.","Differential bleaching among corals was widely variable (mean taxon-BRI = 25.06 AE 18.44%, AESE).","Based on a massive amount of historical data, the index can be used to compare the bleaching responses of corals throughout the world and to predict which corals may be most affected by future bleaching events. ""We can see it with our eyes, and we also clearly see the progression of climate change in our data. ""Coral bleaching is an inescapable example of the effects of climate change.""","Differential bleaching among corals was widely variable (mean taxon-BRI = 25.06 AE 18.44%, AESE). We found that both extrinsic and intrinsic factors have comparable influence within a given site and event (60% and 40% of bleaching response variance of all records explained, respectively). However, when responses of individual taxa are averaged across sites to obtain taxon-BRI, differential response was primarily driven by intrinsic differences among taxa (65% of taxon-BRI variance explained), not conditions across sites (6% explained), nor measurement uncertainty (29% explained).","[2.0, 2.0, 3.0, 3.0]",Biology,train,2.5,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1016/j.neuron.2014.05.028,Biology_88,The Tac2 gene was turned on more strongly during fear learning in mice that were previously exposed to a model of traumatic stress.,"In summary, these studies provide understanding of the role of the Tac2 gene and the CeM in fear processing and provide approaches to intervention for fear-related disorders.","Out of thousands of genes they examined, their ""top gene"" was Tachykinin 2 or Tac2. The Tac2 gene was turned on more strongly during fear learning in mice that were previously exposed to a model of traumatic stress. ""The Tac2 gene is robustly activated after fear learning and belongs to a pathway that can be specifically blocked with a drug,"" Ressler says.","Although other molecular pathways have previously been associated with PTSD, we believe that there will be a number of different mechanisms identified that eventually will synergistically be used to target emotional memory modulation. In summary, these studies provide understanding of the role of the Tac2 gene and the CeM in fear processing and provide approaches to intervention for fear-related disorders. The procedure for detecting Gad65 (AB5082, Chemicon, 1:500) and CaMkIIa (Cell Signaling Solutions, 1:250) was similar as previously described after performing the Tac2 FISH.","[4.0, 3.0, 2.0, 4.0]",Biology,train,3.25,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s13059-018-1434-0,Biology_89,"""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes.","However, considering the rapid increase in sequenced cancer exomes and genomes, we expect that in the near future enough data for genes under negative selection will be available to perform this type of analysis.","""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer. ""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes. We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer.","The lack of substitutions restricts statistical power when it comes to applying a conventional Kaplan-Meier analysis. However, considering the rapid increase in sequenced cancer exomes and genomes, we expect that in the near future enough data for genes under negative selection will be available to perform this type of analysis. In summary, we have identified a conservative estimate of 23 genes under significant negative selection.","[2.0, 4.0, 3.0, 2.0]",Biology,train,2.75,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.4049/jimmunol.1800107,Biology_90,"Additionally, CLCs were shown to promote inflammation in vivo, as evidenced by an increased tissue presence of IL-1b.","2f) , suggesting that lysosomal damage is a likely mechanism by which CLCs can induce IL-1β secretion by macrophages.","In this study, Dr. Latz's team demonstrates that CLCs are engulfed by human macrophages in vitro, resulting in the release of the pro-inflammatory cytokine IL-1b. Additionally, CLCs were shown to promote inflammation in vivo, as evidenced by an increased tissue presence of IL-1b. Importantly, chemical inhibition and small interfering RNA (siRNA) knock-down of NLRP3 in primary human macrophages reduced IL-1B production in response to CLCs, suggesting that the inflammatory response occurs via the NLRP3 inflammasome pathway.","Indeed, CA-074 Me inhibition blocked CLC-induced IL-1β release in a dosedependent manner (Fig. 2f) , suggesting that lysosomal damage is a likely mechanism by which CLCs can induce IL-1β secretion by macrophages. In line with a role for the NLRP3 inflammasome in the intracellular sensing of CLCs, specific inhibition of NLRP3 and caspase-1 with the compounds CRID3 and VX-765, respectively, ablated CLC-induced IL-1β release by hMDMs (Fig.","[3.0, 3.0, 3.0, 3.0, 4.0]",Biology,train,3.2,news,http://ct.moreover.com/?a=38014682083&p=1pl&v=1&x=fA9J7idoQjbuZC8wnt8o2Q
10.1038/ncomms4632,Biology_91,"The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications.",More experiments are necessary to study the applications and limitations of nanomotors in a biosetting.,"The team's nanomotor is an important step toward developing miniature machines that could one day move through the body to administer insulin for diabetics when needed, or target and treat cancer cells without harming good cells. The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications. Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power.",The demonstration of nanomotors for biochemical release as shown above is still in a non-bioenvironment. More experiments are necessary to study the applications and limitations of nanomotors in a biosetting. It will also be interesting to exam the release characteristics from multiple nanomotors.,"[1.0, 1.0, 2.0]",Biology,train,1.3333333333333333,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/1365-2656.12871,Biology_92,"""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus.",There was no evidence for any long-term temporal trend in changes in the survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ).,"It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked."" ""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","than immune adults throughout the year, with monthly survival rates being on average 25% less than for susceptible rabbits (odds ratio of hyperprior-level estimate 0.75, CI 0.68-0.82) (Figure 2 ). There was no evidence for any long-term temporal trend in changes in the survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ). We did not identify any clear seasonal differences in the relative survival rates of RHDV-susceptible versus immune adults (Supporting Information Figure S2 ) despite a variable","[2.0, 2.0, 1.0, 2.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1098/rsos.171474,Biology_93,"That task force ""found that violent video game exposure was associated with: an increased composite aggression score; increased aggressive behavior; increased aggressive cognitions; increased aggressive affect, increased desensitization, and decreased empathy; and increased physiological arousal.""","As a result, we did not split data at an inflection point value or conduct the additional regression tests required to test if the nonlinear relationship between the time participants spends playing violent video games and aggression followed a step function like those found in other large-scale media effects research .","This contradicts the consensus hammered out by an American Psychological Association task force on violent video games in 2017. That task force ""found that violent video game exposure was associated with: an increased composite aggression score; increased aggressive behavior; increased aggressive cognitions; increased aggressive affect, increased desensitization, and decreased empathy; and increased physiological arousal."" The task force also ""concluded that violent video game use is a risk factor for adverse outcomes, but found insufficient studies to examine any potential link between violent video game use and delinquency or criminal behavior.""","This was not possible because the parabolic term was not significant ( p ¼ 0.624), and as such we did not have an empirical basis to calculate the local extrema as planned. As a result, we did not split data at an inflection point value or conduct the additional regression tests required to test if the nonlinear relationship between the time participants spends playing violent video games and aggression followed a step function like those found in other large-scale media effects research . These results did not support the idea that there is a critical amount of violent video game play which serves as a tipping point for aggressive behaviour.","[1.0, 3.0, 2.0, 1.0]",Biology,train,1.75,news,http://ct.moreover.com/?a=38538076628&p=1pl&v=1&x=7Ko5INusmGh9TtCxVKqTtA
10.1016/j.cell.2018.04.034,Biology_94,"""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation.","These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results.","More study is needed to understand this. ""This very promising study suggests that CDK12 loss may be a biomarker for identifying prostate cancer patients who may respond to checkpoint immunotherapy,"" says Howard Soule, Ph.D., executive vice president and chief science officer of the Prostate Cancer Foundation. ""The Prostate Cancer Foundation is proud to have funded this team, which continues to make foundational strides in identifying actionable genomic mutations in prostate cancer and using this information to identify new classes of precision treatments that can be used to improve the lives of men with prostate cancer.""","In line with this possibility, high levels of CCL21 and CCL25 may mediate dendritic cell tumor trafficking and neoantigen-specific T cell clonal expansion (Chan et al., 1999; Gosling et al., 2000; . These findings gave rise to a number of clinical trials for several classes of immunotherapeutics, which have been met with mixed results. A plausible explanation is in the genetics of prostate cancer.","[1.0, 3.0, 2.0]",Biology,train,2.0,news,http://ct.moreover.com/?a=34304617241&p=1pl&v=1&x=JkbWFHiGsGoeqOJxN0A0-A
10.1210/en.2015-2036,Biology_95,"The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis.","These studies revealed Id1 as significantly up-regulated in both the tumors that developed in vitamin D-deficient mice and the VDR KD cells, suggesting that Id1 is repressed by VDR signaling in BCa.","The research highlights a direct link between circulating vitamin D levels and the expression of a gene called ID1, known to be associated with tumor growth and breast cancer metastasis. The finding builds upon several previous studies suggesting that low levels of vitamin D not only increase a person's risk of developing breast cancer, but are also correlated with more-aggressive tumors and worse prognoses. Although the research was conducted primarily in mice and on mouse cells, the researchers found in a study of 34 breast cancer patients that levels of circulating vitamin D were inversely correlated with the expression levels of ID1 protein in their tumors, and they confirmed that a vitamin D metabolite directly controls the expression of the ID1 gene in a human breast cancer cell line.","Our results indicate that loss of vitamin D/VDR signaling is sufficient to convert the cells from nonmetastatic to metastatic. These studies revealed Id1 as significantly up-regulated in both the tumors that developed in vitamin D-deficient mice and the VDR KD cells, suggesting that Id1 is repressed by VDR signaling in BCa. This 'hit' was of particular interest because of the role of Id1 in BCa progression and most intriguing because calcitriol was found to induce, rather than repress, ID1 expression in a colon carcinoma cell line .","[2.0, 3.0, 3.0, 3.0]",Biology,train,2.75,news,http://www.science20.com/news_articles/vitamin_d_deficiency_contributes_to_spread_of_breast_cancer_in_mice_stanford_study_finds-167109
10.2337/db13-1600,Biology_96,"""But neurons in the hindbrain continue to respond to fast onset hypoglycemia even in the absence of peripheral sensors.""","For example, central glycemia may serve as a reference for integrative elements of the brain against which peripheral glycemic input is measured to establish appropriate CRRs.","""This clearly shows that the brain can't detect hypoglycemia under most physiological conditions unless it has this peripheral input,"" Donovan said. ""But neurons in the hindbrain continue to respond to fast onset hypoglycemia even in the absence of peripheral sensors."" The researchers also confirmed that the spinal cord is the actual physical route by which information from the portal vein travels to the hindbrain, overturning the previous belief that it was transmitted via the vagus nerve.","Alternatively, central glucose sensors may serve a synergistic and equally important role with peripheral glucose sensors in responding to hypoglycemia. For example, central glycemia may serve as a reference for integrative elements of the brain against which peripheral glycemic input is measured to establish appropriate CRRs. In this capacity, central glucose sensors might also act primarily to suppress CRRs once euglycemia is reestablished following a hypoglycemic event.","[4.0, 1.0, 2.0, 1.0]",Biology,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1210/en.2015-2036,Biology_99,BF: I would like to emphasize that the questions we are looking at regarding vitamin D deficiency is distinct from the question of if extra vitamin D is beneficial.,"However, treatment with high-dose vitamin D likely has pharmacological effects that are distinct from the pathophysiology of vitamin D deficiency.",My own opinion is a target level of 30-50 ng/mL is reasonable. BF: I would like to emphasize that the questions we are looking at regarding vitamin D deficiency is distinct from the question of if extra vitamin D is beneficial. Our data indicate that avoiding deficiency is likely a good thing but it does not necessarily follow that extra vitamin D is even better.,"(Endocrinology 157: 0000 -0000, 2016) However, treatment with high-dose vitamin D likely has pharmacological effects that are distinct from the pathophysiology of vitamin D deficiency. Provocatively, low vitamin D levels are associated with worse prognostic indicators and outcomes in patients with BCa (9 -11) .","[4.0, 4.0, 4.0, 4.0]",Biology,train,4.0,news,http://www.theepochtimes.com/n3/1987536-vitamin-d-deficiency-promotes-breast-cancer-growth-in-mice/
10.1016/j.cub.2018.06.013,Biology_tweet_0,"New @username paper showing that birds can learn socially to recognize heterospecific alarm calls by acoustic association with known alarm calls.
DOI: 
@username @username @username @username ",Our work demonstrates that wild birds can learn socially to recognize previously unfamiliar sounds as alarm calls.,"New @username paper showing that birds can learn socially to recognize heterospecific alarm calls by acoustic association with known alarm calls.
DOI: 
@username @username @username @username ","Complementary studies of social learning in captivity would be useful in examining in detail the context in which different associations are formed. Our work demonstrates that wild birds can learn socially to recognize previously unfamiliar sounds as alarm calls. In our current experiment, learning could not be asocial because the unfamiliar sounds were never presented at the same time as predator models.","[5.0, 5.0, 4.0, 4.0, 4.0]",Biology,train,4.4,tweets,1025075966756958208
10.1038/s41467-018-06358-z,Biology_tweet_1,"Just published in Nature: ""...In any case, the burned area is robustly projected to increase. The higher the warming level is, the larger is the increase of burned area, ranging from ~40% to ~100% across the scenarios""
","The higher the warming level is, the larger is the increase of burned area, ranging from~40% to~100% across the scenarios.","Just published in Nature: ""...In any case, the burned area is robustly projected to increase. The higher the warming level is, the larger is the increase of burned area, ranging from ~40% to ~100% across the scenarios""
","In any case, the burned area is robustly projected to increase. The higher the warming level is, the larger is the increase of burned area, ranging from~40% to~100% across the scenarios. Our results indicate that significant benefits would be obtained if warming were limited to well below 2°C.","[5.0, 5.0, 5.0, 5.0, 5.0]",Biology,train,5.0,tweets,1047144638677700608
10.1038/s41467-018-05870-6,Biology_tweet_10,Regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic activity in #obesity associated sequelae #NASH #diabetes ,This study demonstrates that hepatic Ago2-mediated RNA silencing regulates energy expenditure during the course of obesity and its inactivation protects from obesity-associated glucose intolerance and hepatic steatosis in mice.,Regulation of energy metabolism by Ago2 provides a novel paradigm in which RNA silencing plays an integral role in determining basal metabolic activity in #obesity associated sequelae #NASH #diabetes ,"Upon loading of Ago proteins with mature miRNAs produced by the endoribonuclease Dicer 18 , RISC represses the expression of targeted mRNA through RNA silencing . This study demonstrates that hepatic Ago2-mediated RNA silencing regulates energy expenditure during the course of obesity and its inactivation protects from obesity-associated glucose intolerance and hepatic steatosis in mice. Importantly, we discover novel roles of Ago2 in orchestrating the expression of a subset of miRNAs, including miR-802, miR-103/107, and miR148a, and in the regulation of AMP-activated protein kinase (AMPK) activation linked to protein biosynthesis-mediated energy consumption.","[4.0, 4.0, 4.0]",Biology,train,4.0,tweets,1039090256606310400
10.1073/pnas.1504869112,Biology_tweet_101,"Lianas reduce tropical forest carbon accumulation and storage.. read all about it:

 ","Lianas, per-unit biomass, have a much stronger competitive effect on trees than do other trees (3), and our findings appear to represent the unique effect of lianas on forest carbon dynamics and not merely the effect of biomass removal.","Lianas reduce tropical forest carbon accumulation and storage.. read all about it:

 ","Because biomass dynamics of lianas are included in the whole-forest estimates, our findings corroborate earlier research that lianas themselves do not compensate for the loss in tree biomass that they cause . Lianas, per-unit biomass, have a much stronger competitive effect on trees than do other trees (3), and our findings appear to represent the unique effect of lianas on forest carbon dynamics and not merely the effect of biomass removal. This point is confirmed by our inclusion of lianas in the biomass calculations in the control plots.","[3.0, 5.0, 4.0, 4.0, 4.0]",Biology,train,4.0,tweets,653902927493337088
10.3945/jn.113.188441,Biology_tweet_102,"Avoid! Study reveals instant noodles consumption increases chance of heart disease, #diabetes &amp; stroke:  #diet #health","The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","Avoid! Study reveals instant noodles consumption increases chance of heart disease, #diabetes &amp; stroke:  #diet #health","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age. Our study had several limitations.","[2.0, 4.0, 4.0, 4.0, 3.0]",Biology,train,3.4,tweets,502704410107977728
10.1186/s40168-015-0071-z,Biology_tweet_103,"A reason for colic in breast fed babies? RT @username: Mom's gene affects bifidobacteria in the breastfed infant gut 
",It may be that the deficit in bifidobacteria that nonsecretor-fed infants experience is due to the likelihood of acquiring a species of bifidobacteria with metabolic abilities appropriate for the type of milk being consumed.,"A reason for colic in breast fed babies? RT @username: Mom's gene affects bifidobacteria in the breastfed infant gut 
","Understanding the mechanism behind these differences will prove crucial to potentially compensating for this problem, perhaps through carefully chosen prebiotics and/or probiotics. It may be that the deficit in bifidobacteria that nonsecretor-fed infants experience is due to the likelihood of acquiring a species of bifidobacteria with metabolic abilities appropriate for the type of milk being consumed. As modern hygiene standards and other cultural practices may lead to a reduction in the exposure levels to different bifidobacterial species, the phenomenon of the low bifidobacteria infant might be an artefact of developed countries.","[4.0, 2.0, 4.0, 3.0]",Biology,train,3.25,tweets,587636672117911553
10.3945/jn.113.188441,Biology_tweet_104,"Noodles: Instant friend or fiend? New study shows link to distinct cardiometabolic risk factors, from Korean studies. ","We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women.","Noodles: Instant friend or fiend? New study shows link to distinct cardiometabolic risk factors, from Korean studies. ","As shown in previous reports, a high intake of refined carbohydrates such as white rice is known to increase the risk of type 2 diabetes, therefore nullifying the possible association between the MP and hyperglycemia in our study. We found that the consumption of instant noodles was associated with an increased prevalence of metabolic syndrome and marginally associated with abdominal obesity, independent of the major dietary patterns, in women. Our findings suggest that instant noodle consumption alone might confer a higher cardiometabolic risk independent of overall dietary patterns.","[5.0, 5.0, 4.0]",Biology,train,4.666666666666667,tweets,501383761108672512
10.1126/sciadv.aat5107,Biology_tweet_107,"Our hands on biology education kits are out @username! A fun and special collaboration between scientists and K-12 students and teachers.
#synbio #STEMeducation #scienceoutreach @username @username 

","In sum, BioBits™ Bright represents a comprehensive set of educational resources for synthetic biology akin to the ""chemistry set"" that brought chemistry education to the masses and inspired generations of scientists.","Our hands on biology education kits are out @username! A fun and special collaboration between scientists and K-12 students and teachers.
#synbio #STEMeducation #scienceoutreach @username @username 

","We also plan to launch a website where students can share their data and biological program designs with other users of these kits from around the world. In sum, BioBits™ Bright represents a comprehensive set of educational resources for synthetic biology akin to the ""chemistry set"" that brought chemistry education to the masses and inspired generations of scientists. This is made possible by our in-house freeze-dried reactions, which are two orders of magnitude more affordable than existing commercial cell-free kits, at just ~US$0.01 per microliter of reaction volume (table S3) compared to ~US$1 per microliter (Promega L110; NEB E6800S).","[2.0, 5.0, 5.0, 4.0, 2.0]",Biology,train,4.0,tweets,1024733214362009601
10.1098/rstb.2015.0168,Biology_tweet_108,"Our paper in PTRS, just published:Multiscale perspectives of fire, climate and humans in WNA and the Jemez Mtns, USA ",Temperature-specific palaeoclimate reconstructions relevant to the south-west do show the early decades of the 1600s had relatively cool summers during this period of infrequent widespread fires in the Jemez Mountains.,"Our paper in PTRS, just published:Multiscale perspectives of fire, climate and humans in WNA and the Jemez Mtns, USA ","Although the SEA results support an interpretation of human interference with interannual climate-fire associations before 1680 CE, it is possible that longer-term climate patterns could have played some role in changing fire patterns. Temperature-specific palaeoclimate reconstructions relevant to the south-west do show the early decades of the 1600s had relatively cool summers during this period of infrequent widespread fires in the Jemez Mountains. However, decade to multi-decade temperature and fire trends in our rstb.royalsocietypublishing.org Phil.","[1.0, 3.0, 2.0]",Biology,train,2.0,tweets,735222896734310400
10.1073/pnas.1220333110,Biology_tweet_109,"Alpha, beta &amp; gamma diversity all affect ecosystem multifunctionality ","Thus, in addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities.","Alpha, beta &amp; gamma diversity all affect ecosystem multifunctionality ","Higher β diversity also reduced the variability in multifunctionality. Thus, in addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities. The effects of individual species (3-5) and α diversity (6) also become stronger as more functions are considered simultaneously (ecosystem multifunctionality).","[3.0, 3.0, 4.0, 3.0]",Biology,train,3.25,tweets,342208126310817792
10.1098/rsos.171474,Biology_tweet_11,"An #OpenScience study on 1000 British teenagers aged between 14 and 15 and their carers finds no evidence that playing violent video games leads to aggressive behaviour  
cc. @username @username ",Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers.,"An #OpenScience study on 1000 British teenagers aged between 14 and 15 and their carers finds no evidence that playing violent video games leads to aggressive behaviour  
cc. @username @username ","Keeping in mind the steps taken to ensure methodological rigour, the current results bear directly on the contentious literature surrounding games. Results from these confirmatory analyses provided evidence that adolescents' recent violent video game play is not a statistically or practically significant correlate of their aggressive behaviour as judged by carers. Preregistered sensitivity and exploratory analyses demonstrated this finding was consistent across three different operationalizations of violent game content and two ways of measuring key adolescent behaviours relating to aggressive and prosocial behaviours.","[5.0, 4.0, 5.0, 4.0]",Biology,train,4.5,tweets,1095608563895074816
10.1007/s10336-017-1477-0,Biology_tweet_111,Our new paper - Taxonomic status of Liberian Greenbul - genetics suggests plumage variant of Icterine Greenbul  ,We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul.,Our new paper - Taxonomic status of Liberian Greenbul - genetics suggests plumage variant of Icterine Greenbul  ,"The presumed nuND2 appears to be highly conserved: the two icterinus sequences isolated were identical, 1 bp different from the leucolepis allele, with a further 2 bp distance to albigularis. We therefore believe this fragment to represent part of the true mitochondrial ND2 of Liberian Greenbul. Based on a short fragment of sequence, many of the nodes in the tree have equivocal bootstrap support, and it does not represent a robust greenbul phylogeny.","[2.0, 4.0, 1.0, 2.0, 2.0]",Biology,train,2.2,tweets,885409579034718208
10.1073/pnas.1405000111,Biology_tweet_112,Very interesting paper reveals surprising evolutionary history of bird migration ... ,"Contrary to expectations, we found that long-distance migration primarily evolved through evolutionary shifts of geographic range south for the winter out of North America, as opposed to north for the summer.",Very interesting paper reveals surprising evolutionary history of bird migration ... ,"These results illuminate how the evolution of seasonal migration has contributed to greater niche conservatism among tropical members of this diverse avian radiation. Contrary to expectations, we found that long-distance migration primarily evolved through evolutionary shifts of geographic range south for the winter out of North America, as opposed to north for the summer. Our results further suggest that seasonal migration promoted colonization of the tropics from North America.","[4.0, 3.0, 3.0]",Biology,train,3.333333333333333,tweets,514381961385615360
10.1038/s41467-019-08382-z,Biology_tweet_113,Check this out! New paper from @username lab in @username! @username and co-workers have shed light on how the protein Hel2 recognises stalled ribosomes and triggers the quality control pathway. Read more at:  ,Western blot analyses showed that the truncated proteins were more abundant than wild-type Hel2 (~1.8-fold for Hel2 1-543 and~1.9fold for Hel2 ).,Check this out! New paper from @username lab in @username! @username and co-workers have shed light on how the protein Hel2 recognises stalled ribosomes and triggers the quality control pathway. Read more at:  ,6a ). Western blot analyses showed that the truncated proteins were more abundant than wild-type Hel2 (~1.8-fold for Hel2 1-543 and~1.9fold for Hel2 ). Both truncated proteins also purified more efficiently in the CRAC procedure (~1.5-2.1-fold more efficiently for Hel2 1-543 and~2.4-8.4-fold more efficiently for Hel2 1-492 ) as determined following tobacco etch virus (TEV) elution (Supplementary Fig.,"[2.0, 3.0, 1.0, 2.0, 2.0]",Biology,train,2.0,tweets,1093046579366383617
10.1016/j.immuni.2018.03.027,Biology_tweet_114,Controlling Germinal Center B cell Decisions | TFH interaction strength regulates GC re-entry vs PC differentiation | TomoKurosaki @username @username  ,These data support a model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation.,Controlling Germinal Center B cell Decisions | TFH interaction strength regulates GC re-entry vs PC differentiation | TomoKurosaki @username @username  ,"hi CD69 hi cells, thereby affording more stable T follicular helper (Tfh)-GC B cell contacts. These data support a model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation. Higher expression of ICAM-1 and SLAM in those cells facilitates more stable contacts with Tfh cells, suggesting that strength of Tfh-GC B cell interaction critically regulates formation of plasma cell precursors.","[3.0, 3.0, 1.0, 3.0]",Biology,train,2.5,tweets,986801572331053056
10.1126/science.aam7470,Biology_tweet_115,Chronic neonicotinoid exposure reduces #honeybee health near corn. Nice work @username @username @username  ,"However, in the absence of seasonlong data, it is impossible to rule out that honey bees are also chronically exposed to sublethal levels of NNIs after planting.",Chronic neonicotinoid exposure reduces #honeybee health near corn. Nice work @username @username @username  ,"The timing of honey bee deaths in Ontario, Québec, and Indiana, along with the presence of NNI residues in dead bees and hives in the spring (11, , suggested that NNI-contaminated dust generated during seeding was the main route of acute exposure ( . However, in the absence of seasonlong data, it is impossible to rule out that honey bees are also chronically exposed to sublethal levels of NNIs after planting. We detected 26 different agrochemicals that included miticides, fungicides, herbicides, NNIs, and other insecticides (tables S1 and S5).","[1.0, 3.0, 3.0, 3.0]",Biology,train,2.5,tweets,880487738293833728
10.1111/gcb.13876,Biology_tweet_116,Stopping #deforestation and letting harvested forests grow could remove 120bn tons of #CO2 by 2100  @username,"Accounting for these delayed emissions, the net sink for carbon (declining emissions and declining rates of forest re-growth) was greatest immediately after harvests ceased and declined as regrowing forests aged.",Stopping #deforestation and letting harvested forests grow could remove 120bn tons of #CO2 by 2100  @username,"Putting the tropical and temperate zone and boreal forests together, yielded a global gross sink (2006) (2007) (2008) (2009) (2010) (2011) (2012) (2013) (2014) (2015) of 4.4 PgC/year (Table 3) . Accounting for these delayed emissions, the net sink for carbon (declining emissions and declining rates of forest re-growth) was greatest immediately after harvests ceased and declined as regrowing forests aged. The net global carbon sink obtainable if deforestation and harvests were stopped would be À34 PgC by 2100 (15 + 19).","[4.0, 5.0, 3.0]",Biology,train,4.0,tweets,899963498612088833
10.1038/s41586-018-0189-9,Biology_tweet_117,A bit of a change to the pathology here! @username et al have just published a massive european study in nature on 'Enviroment and host as large-scale controls of ectomycorrhizal fungi'. It's worth a look!  Congratulations! ,"We conclude that environmental and host factors explain most of the variation in ectomycorrhizal diversity, that the environmental thresholds used as major ecosystem assessment tools need adjustment and that the importance of belowground specificity and plasticity has previously been underappreciated.",A bit of a change to the pathology here! @username et al have just published a massive european study in nature on 'Enviroment and host as large-scale controls of ectomycorrhizal fungi'. It's worth a look!  Congratulations! ,"We quantify host specificity and reveal plasticity in functional traits involved in soil foraging across gradients. We conclude that environmental and host factors explain most of the variation in ectomycorrhizal diversity, that the environmental thresholds used as major ecosystem assessment tools need adjustment and that the importance of belowground specificity and plasticity has previously been underappreciated. However, determinants of ectomycorrhizal diversity at local scales are not necessarily their primary drivers at larger scales 17 , and ectomycorrhizal communities are often dominated by hardly culturable and non-fruiting or inconspicuously fruiting fungi 18 .","[3.0, 2.0, 2.0, 5.0]",Biology,train,3.0,tweets,1004411550348791808
10.1038/s41467-018-05396-x,Biology_tweet_118,"Check out this paper discussing ""Block copolymer #crystalsomes with an ultrathin shell to extend #blood circulation time"" with the help of #AFM experiments!
 ",The ultra-long circulation time of the 7-day crystallized BCCs arises from the high crystallinity and uniform crystalline chain packing on the curved BCC shells which minimize defect formation in the crystals.,"Check out this paper discussing ""Block copolymer #crystalsomes with an ultrathin shell to extend #blood circulation time"" with the help of #AFM experiments!
 ","Combining all these results, we can conclude that there is a close correlation between the BCC crystallinity and the blood circulation time, shown in Fig. The ultra-long circulation time of the 7-day crystallized BCCs arises from the high crystallinity and uniform crystalline chain packing on the curved BCC shells which minimize defect formation in the crystals. In 3-day, 5-day crystallized BCCs and the previously reported polymersome cases, relatively poorly controlled crystals lead to defect-rich particles, which may be prone to disassembly under blood flow.","[3.0, 3.0, 1.0, 3.0]",Biology,train,2.5,tweets,1063084209894383616
10.1016/j.celrep.2014.05.027,Biology_tweet_119,@username paper: neurons transplanted into #Parkinson’s-affected brains appear healthy after 14 years  #OA Week,"A general assessment of the integrity of the grafted TH-immunoreactive neurons in all patients revealed cells with a healthy appearance, including a robust cell soma and absence of signs of atrophy ( Figures 1A-1C , 1F-1H, 1K-1M, and 1P-1R).",@username paper: neurons transplanted into #Parkinson’s-affected brains appear healthy after 14 years  #OA Week,"Postmortem examinations demonstrated that grafted dopaminergic neurons survived for up to 14 years posttransplantation. A general assessment of the integrity of the grafted TH-immunoreactive neurons in all patients revealed cells with a healthy appearance, including a robust cell soma and absence of signs of atrophy ( Figures 1A-1C , 1F-1H, 1K-1M, and 1P-1R). In two independent patients at 4 years posttransplantation ( Figures 1A-1J ), an examination of DAT/TH immunostaining at low magnification (Figures 1A and 1F) showed dense DAT and TH expression in the reinnervated putamen and caudate in areas both near to and farther away from the graft.","[1.0, 5.0, 1.0]",Biology,train,1.0,tweets,525679687767703552
10.1038/s41556-018-0178-0,Biology_tweet_12,"BAP1 mutations are seen in #leukemia, #mesothelioma, #cholangiocarcinoma, uveal #melanoma &amp; renal cancer. 
Boyi Gan from @username has shown how BAP1 suppresses tumor formation through inhibition of SLC7A11 transporter &amp; elevated ferroptosis.
 ","Furthermore, we show that BAP1 inhibits tumour development partly through SLC7A11 and ferroptosis, and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis.","BAP1 mutations are seen in #leukemia, #mesothelioma, #cholangiocarcinoma, uveal #melanoma &amp; renal cancer. 
Boyi Gan from @username has shown how BAP1 suppresses tumor formation through inhibition of SLC7A11 transporter &amp; elevated ferroptosis.
 ","Here, integrated transcriptomic, epigenomic and cancer genomic analyses link BAP1 to metabolismrelated biological processes, and identify cystine transporter SLC7A11 as a key BAP1 target gene in human cancers. Furthermore, we show that BAP1 inhibits tumour development partly through SLC7A11 and ferroptosis, and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis. Together, our results uncover a previously unappreciated epigenetic mechanism coupling ferroptosis to tumour suppression.","[3.0, 5.0, 3.0, 4.0]",Biology,train,3.75,tweets,1039278544168333312
10.1038/s41568-018-0020-9,Biology_tweet_120,"Why have inhibitors of heat shock proteins so far failed? Gabriela Chiosis &amp; colleagues provide their perspective on why &amp; suggest how we can better develop and implement drugs targeting the chaperome to treat cancer.

 ","Ultimately, then, classical approaches to drug discovery are inappropriate when one targets the chaperome.","Why have inhibitors of heat shock proteins so far failed? Gabriela Chiosis &amp; colleagues provide their perspective on why &amp; suggest how we can better develop and implement drugs targeting the chaperome to treat cancer.

 ","This realization has implications for the development of chaperome inhibitors and emphasizes the importance of considering factors such as the residence time, pharmacokinetics (PKs) and pharmacodynamics (PDs) to fully appreciate the distinctions between HSP90 agents 145 (Box 4). Ultimately, then, classical approaches to drug discovery are inappropriate when one targets the chaperome. Instead, attention must be paid during drug development to the ability of the compound to modulate relevant, disease-specific chaperome species.","[2.0, 4.0, 3.0]",Biology,train,3.0,tweets,999647430932156416
10.1038/s41467-019-08895-7,Biology_tweet_121,Myocardial microRNA exosome messengers talk to the bone marrow ,"These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between ischemic heart and the remote BM organ.",Myocardial microRNA exosome messengers talk to the bone marrow ,"Our work reveals that exosomes released from the ischemic heart are in fact mediating the systemic response of BM PCs to the site of injury. These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between ischemic heart and the remote BM organ. In this study we found exosomes mediate transfer of myo-miRs to BM.","[4.0, 4.0, 5.0]",Biology,train,4.333333333333333,tweets,1100714842296586240
10.1038/s41467-018-07557-4,Biology_tweet_122,"New article in Nature Communications shows that melting permafrost due to #ClimateChange is a real risk in the #Arctic and that 1 million people in the global North live in high risk areas, especially in Russia, Canada and Alaska ","However, I s does not include information on permafrost thaw or other potential hazard-inducing factors and in our study, I s was based on relatively coarse-scaled GIC data.","New article in Nature Communications shows that melting permafrost due to #ClimateChange is a real risk in the #Arctic and that 1 million people in the global North live in high risk areas, especially in Russia, Canada and Alaska ","The value of I a ranged from 1.0 (lowest hazard potential) to 3.0 (highest hazard potential). However, I s does not include information on permafrost thaw or other potential hazard-inducing factors and in our study, I s was based on relatively coarse-scaled GIC data. In contrast, I a considers different affecting factors and introduces case-specific expert knowledge into the process but represents a relatively complex and subjective approach in the development of an index for infrastructure hazard assessment.","[4.0, 3.0, 3.0, 3.0, 2.0]",Biology,train,3.0,tweets,1073214749998047233
10.1111/ele.12889,Biology_tweet_123,"Decreased forest regeneration over the last 15 years suggests forests are in a precarious position 
","The proportion of dry forest sites with seedling densities exceeding recruitment thresholds was also lower after 21st-century wildfires, declining from 49% (in sites that burned prior to 2000) to 30% (in sites burned since 2000; v 2 = 14.3, P = 0.0002).","Decreased forest regeneration over the last 15 years suggests forests are in a precarious position 
","2, v 2 = 8.5, P = 0.004). The proportion of dry forest sites with seedling densities exceeding recruitment thresholds was also lower after 21st-century wildfires, declining from 49% (in sites that burned prior to 2000) to 30% (in sites burned since 2000; v 2 = 14.3, P = 0.0002). Moist forest types exhibited a similar decline in regeneration (v 2 > 7.5, P < 0.01), but the proportion of sites with seedlings or densities exceeding recruitment thresholds was greater than 65% in both time periods, declining from 91 to 65%.","[4.0, 4.0, 1.0, 4.0]",Biology,train,4.0,tweets,940926112766537728
10.1111/ecog.03303,Biology_tweet_124,"Felids face continued threat from declining prey richness

#rewilding #megafauna #biodiversity ",A significant positive correlation was recorded between the number of prey species lost and the number of large-felid species lost from a cell.,"Felids face continued threat from declining prey richness

#rewilding #megafauna #biodiversity ","In total, 86% of cells recorded at least one additional felid species in our present-natural counterfactual, and up to 4-5 more large-felid species in 10% of the cells. A significant positive correlation was recorded between the number of prey species lost and the number of large-felid species lost from a cell. Our results draw attention to the continuation of a trend of megafauna decline that began with the emergence of hominins in the Pleistocene.","[5.0, 5.0, 4.0, 4.0, 5.0]",Biology,train,4.6,tweets,852118059770941440
10.1016/j.cell.2013.09.058,Biology_tweet_125,A new mechanism of obesity and T2D that appears to be reversible by metformin  ,"We identified multiple rare variants in KSR2 that disrupt signaling through the Raf-MEK-ERK pathway and impair cellular fatty acid oxidation and glucose oxidation in transfected cells; effects that can be ameliorated by the commonly prescribed antidiabetic drug, metformin.",A new mechanism of obesity and T2D that appears to be reversible by metformin  ,"Targeted deletion of Ksr2 leads to obesity in mice, suggesting a role in energy homeostasis. We identified multiple rare variants in KSR2 that disrupt signaling through the Raf-MEK-ERK pathway and impair cellular fatty acid oxidation and glucose oxidation in transfected cells; effects that can be ameliorated by the commonly prescribed antidiabetic drug, metformin. These data establish KSR2 as an important regulator of energy intake, energy expenditure, and substrate utilization in humans.","[5.0, 3.0, 2.0]",Biology,train,4.0,tweets,394460685750398976
10.1038/s41467-018-05738-9,Biology_tweet_126,Scientist Katey Walter Anthony has a new article in Nature on carbon emissions and lake thaw: ,"We acknowledge that present-day emissions associated with abrupt thaw may be conservative since gross lake-area increases in some regions are higher (e.g., > 50% in Quebec 85 and > 23% in West Siberia 86 ), potentially due to hydrological changes in addition to permafrost thaw.",Scientist Katey Walter Anthony has a new article in Nature on carbon emissions and lake thaw: ,"This range of gross lake expansion is comparable to our observation of gross lake-area increase in northern and western Alaska (i.e., 1999-2014, 1.1-1.7% gross lake area increase upscaled to 5-7% assuming similar expansion/formation rates over the past 60 years; Supplementary Table 3, Fig. We acknowledge that present-day emissions associated with abrupt thaw may be conservative since gross lake-area increases in some regions are higher (e.g., > 50% in Quebec 85 and > 23% in West Siberia 86 ), potentially due to hydrological changes in addition to permafrost thaw. The formation/expansion of new thermokarst-lake areas and subsequent sublake talik growth is not the only mechanism of abrupt permafrost degradation making newly thawed permafrost carbon available for microbial decomposition.","[2.0, 3.0, 2.0, 5.0, 2.0]",Biology,train,2.8,tweets,1030179932117204993
10.1021/cb4008953,Biology_tweet_127,"Med Chem Malaria Paper of the Day: 
ACS Chem Biol
ChEMBL Score: 8.52 #medchem #antimalarial #chembl #malaria_data",This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum.,"Med Chem Malaria Paper of the Day: 
ACS Chem Biol
ChEMBL Score: 8.52 #medchem #antimalarial #chembl #malaria_data","Moreover, the additional parasiticidal effect exerted by 1 and 6 in the drug-resistant parasites was attributable, at least in part, to their ability to inhibit PfCRT CQR . This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum. This phenomenon is thought to be due to an increase in the efflux of the drug from the DV, a decrease in its uptake into the DV, or a combination of both.","[5.0, 2.0, 1.0, 2.0, 1.0]",Biology,train,2.0,tweets,438659714285830144
10.1038/s41467-018-08278-4,Biology_tweet_128,"Proteins regenerate amputated limbs 😍 Making joints is tough - even animals that regrow limbs can rarely regrow joints. These amputations treated w/ two sequential proteins grew bone &amp; joints 🙌 Read 

#health #medicine #science #amputation #regeneration ",Chondrogenic genes are not expressed by cells of the amputation wound in BSA-treated control digits ( Fig.,"Proteins regenerate amputated limbs 😍 Making joints is tough - even animals that regrow limbs can rarely regrow joints. These amputations treated w/ two sequential proteins grew bone &amp; joints 🙌 Read 

#health #medicine #science #amputation #regeneration ","1l) , but not by cells of the BSA-treated digits ( Supplementary Fig. Chondrogenic genes are not expressed by cells of the amputation wound in BSA-treated control digits ( Fig. In BMP9-treated non-cavity-forming digits, we find transcripts of Col2a1, Sox9, Acan, Fmod and Ucma up-regulated at the distal end of the stump (Fig.","[1.0, 1.0, 2.0]",Biology,train,1.3333333333333333,tweets,1093972240092282880
10.1073/pnas.1420105111,Biology_tweet_129,"Innovative approach improves #aptamer efficacy in #cancer treatment- hybridize photo-labile oligonucleotide
 @username",Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines.,"Innovative approach improves #aptamer efficacy in #cancer treatment- hybridize photo-labile oligonucleotide
 @username","Furthermore, the relative distribution of the aptamer to the tumor was enhanced in relation to uptake by the liver and kidneys. Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines. (Fig.","[4.0, 5.0, 2.0, 3.0]",Biology,train,3.5,tweets,534642529950371841
10.1186/s40168-015-0071-z,Biology_tweet_13,Infants whose mothers have reduced breast milk oligosaccharides develop bifidobacteria-laden microbiota later ,"A broader range of bifidobacterial species were positively correlated with the amounts of overall bifidobacteria within secretor-fed infants than non-secretor-fed infants, suggesting that the presence of 2′-fucosylated sugars allows a broader array of bifidobacterial species to colonize the gut environment.",Infants whose mothers have reduced breast milk oligosaccharides develop bifidobacteria-laden microbiota later ,"However, there was a large difference in which species of bifidobacteria thrived in each group of infants (defined as a species whose presence tended to lead to domination of the microbiota by bifidobacteria). A broader range of bifidobacterial species were positively correlated with the amounts of overall bifidobacteria within secretor-fed infants than non-secretor-fed infants, suggesting that the presence of 2′-fucosylated sugars allows a broader array of bifidobacterial species to colonize the gut environment. According to our fecal isolate data, bifidobacteria that can grow on 2′-fucosylated substrates are relatively uncommon, but represent a larger proportion of total bifidobacteria in secretor-fed infants, suggesting that this substrate is related to the competitive fitness of these strains.","[4.0, 4.0, 4.0, 3.0, 3.0]",Biology,train,3.6,tweets,589260682006138880
10.1038/nature12167,Biology_tweet_131,RT @username: first ever class F GPCR structure:  human SMO receptor with antagonist,"Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration .",RT @username: first ever class F GPCR structure:  human SMO receptor with antagonist,"The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity. Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration . 1 ) reveals a canonical GPCR 7TM bundle fold with a short helix VIII packed parallel to the membrane bilayer.","[4.0, 1.0, 3.0, 1.0]",Biology,train,1.0,tweets,329683182381314049
10.1038/s41467-018-05870-6,Biology_tweet_132,"New findings from Takahisa Nakamura, PhD: Deleting a key protein from the livers of mice helped stave off #obesity, preventing both #diabetes and #fattyliverdisease. #CincyKidsScience. Read the study: ","These Ago2-mediated molecular events may solve the paradox of protein biosynthesis in the obese liver, demonstrate a new mechanism in the regulation of basal metabolic activity, and provide a novel therapeutic target for metabolic diseases.","New findings from Takahisa Nakamura, PhD: Deleting a key protein from the livers of mice helped stave off #obesity, preventing both #diabetes and #fattyliverdisease. #CincyKidsScience. Read the study: ","This condition can amplify activation of AMPK and its substrates ULK1, MFF, and Pgc1α, leading to improved mitochondrial capacity and quality, which in turn generates sufficient energy for protein biosynthesis. These Ago2-mediated molecular events may solve the paradox of protein biosynthesis in the obese liver, demonstrate a new mechanism in the regulation of basal metabolic activity, and provide a novel therapeutic target for metabolic diseases. In conclusion, our results highlight that Ago2 uniquely regulates energy production and consumption in the liver, and suggest hepatic Ago2-mediated RNA silencing is a key regulator of glucose and lipid metabolism during the pathogenesis of obesity.","[2.0, 4.0, 2.0, 3.0, 3.0]",Biology,train,2.8,tweets,1039138905902202880
10.1038/s41467-018-07557-4,Biology_tweet_133,"Our brand new research highlights the risks of #permafrost thaw on #Arctic #infrastucture  I'll present the permafrost #modeling and #geohazard assessments tomorrow morning in #AGU18 at session GC31B. @username
@username
@username","Moreover, we were able to quantify and show the magnitude of infrastructure at risk across the circumpolar permafrost domain.","Our brand new research highlights the risks of #permafrost thaw on #Arctic #infrastucture  I'll present the permafrost #modeling and #geohazard assessments tomorrow morning in #AGU18 at session GC31B. @username
@username
@username","Consequently, detailed hazard maps and geospatial data-based computations, such as those presented here, are of importance to enable planners and policymakers to identify both high-and low hazard areas when planning future infrastructure at urban and settlement scales 33 . Moreover, we were able to quantify and show the magnitude of infrastructure at risk across the circumpolar permafrost domain. The major advantage of the approach presented here is that hazard quantification can be conducted with any available infrastructure or population dataset (also using planned infrastructure and future population if suitable high-quality datasets and projections are available) and for any policy-relevant global warming scenario.","[3.0, 5.0, 2.0]",Biology,train,4.0,tweets,1072537852179832833
10.1186/gb-2013-14-7-r73,Biology_tweet_134,So you think you know about lincRNAs? But what about vlincRNAs?  includes Helicos sequencing! #transcriptome #genomics,"Of 2,285 vlincRNAs found in cancerous or immortalized cells/tissues, 1,088 (47.7%) occurred in the non-cancerous cell lines or blood.",So you think you know about lincRNAs? But what about vlincRNAs?  includes Helicos sequencing! #transcriptome #genomics,"A complex normal human tissue, blood, revealed expression of 613 vlincRNAs, of which 331 (p-value 2.03 × 10 -49 ) overlap ENCODE vlincRNAs. Of 2,285 vlincRNAs found in cancerous or immortalized cells/tissues, 1,088 (47.7%) occurred in the non-cancerous cell lines or blood. While cancerous cells have highlyrearranged genomes and, in theory, could produce non-functional vlincRNA transcripts that reflect those re-arrangements, this argument cannot be made about the Figure S1 .","[2.0, 4.0, 2.0, 4.0]",Biology,train,3.0,tweets,359668435149520896
10.1111/gcb.13276,Biology_tweet_135,"Starting a little late on #365papers, heres number 1: Swain et al 16, Coral bleaching response index... ","Differential bleaching among corals was widely variable (mean taxon-BRI = 25.06 AE 18.44%, AESE).","Starting a little late on #365papers, heres number 1: Swain et al 16, Coral bleaching response index... ","Differential bleaching among corals was widely variable (mean taxon-BRI = 25.06 AE 18.44%, AESE). We found that both extrinsic and intrinsic factors have comparable influence within a given site and event (60% and 40% of bleaching response variance of all records explained, respectively). However, when responses of individual taxa are averaged across sites to obtain taxon-BRI, differential response was primarily driven by intrinsic differences among taxa (65% of taxon-BRI variance explained), not conditions across sites (6% explained), nor measurement uncertainty (29% explained).","[1.0, 4.0, 1.0, 3.0]",Biology,train,1.0,tweets,817132227951816705
10.1098/rsos.180695,Biology_tweet_136,"researchers report people set their home thermostats in the USA in ways...""most similar in climate to the outdoor conditions of west central Kenya"" (N = 37, lead author's last name is ""Just""...is this a Dr Just-so story?)  ",This literature suggests that the many ways in which the climate people prefer for their homes might be modulated and why.,"researchers report people set their home thermostats in the USA in ways...""most similar in climate to the outdoor conditions of west central Kenya"" (N = 37, lead author's last name is ""Just""...is this a Dr Just-so story?)  ","Thermal comfort can be influenced by culture , by wind speed and humidity [27 -30] and mean radiant temperature . This literature suggests that the many ways in which the climate people prefer for their homes might be modulated and why. But what these do not change is the reality that thermal comfort itself, evolved.","[4.0, 4.0, 3.0, 1.0, 2.0]",Biology,train,2.8,tweets,1108704958982078464
10.1186/s13059-018-1434-0,Biology_tweet_137,"Negative selection in cancer, after all...and it's also the immune system! Great work by @username @username and colleagues out in @username ",We present evidence for extensive negative selection over somatic point mutations in cancer exomes.,"Negative selection in cancer, after all...and it's also the immune system! Great work by @username @username and colleagues out in @username ",These studies help to shed light upon the mechanisms underlying immune evasion and provide insights for improving cancer immunotherapies in the future. We present evidence for extensive negative selection over somatic point mutations in cancer exomes. We exploited a large cancer exome dataset based on 26 tumor types and uncovered a set of 25 genes under negative selection (cancer-essential) and a set of 14 genes under positive selection (cancer drivers).,"[4.0, 5.0, 5.0, 4.0, 2.0]",Biology,train,4.0,tweets,1002465950120251392
10.1073/pnas.1620079114,Biology_tweet_138,"Erythritol is associated with gains in body weight &amp; fat; also, it isn't just a dietary sweetener, bodies make it   ","However, the consistency of the erythritol results in both the central adiposity and usual glycemia comparisons lends strength to the findings, and the cluster of metabolites has biological plausibility.","Erythritol is associated with gains in body weight &amp; fat; also, it isn't just a dietary sweetener, bodies make it   ","The FDR-corrected statistical tests presented herein are not as robust as tests that account for both biological and technical variation . However, the consistency of the erythritol results in both the central adiposity and usual glycemia comparisons lends strength to the findings, and the cluster of metabolites has biological plausibility. This pool-based study delivers two unique results about metabolite abundance related to a one-time measurement of glycemia and longitudinal increase in central adiposity.","[3.0, 4.0, 3.0]",Biology,train,3.333333333333333,tweets,861694155268993026
10.1038/s41598-018-21058-w,Biology_tweet_14,Can Far-UVC light help control the spread of airborne-mediated microbial diseases? We test how well our 222-nm technology works on airborne #viruses in our latest publication found on @username (its open access!)  #Flu2018 #flu,"If these results are confirmed in other scenarios, it follows that the use of overhead low-level far-UVC light in public locations may represent a safe and efficient methodology for limiting the transmission and spread of airborne-mediated microbial diseases such as influenza and tuberculosis.",Can Far-UVC light help control the spread of airborne-mediated microbial diseases? We test how well our 222-nm technology works on airborne #viruses in our latest publication found on @username (its open access!)  #Flu2018 #flu,"However as discussed above, based on biophysical considerations and in contrast to the known human health safety issues associated with conventional germicidal 254-nm broad-spectrum UVC light, far-UVC light does not appear to be cytotoxic to exposed human cells and tissues in vitro or in vivo . If these results are confirmed in other scenarios, it follows that the use of overhead low-level far-UVC light in public locations may represent a safe and efficient methodology for limiting the transmission and spread of airborne-mediated microbial diseases such as influenza and tuberculosis. This results in blocking more than 95% of the UV radiation exiting the UVGI fixture, with substantial decrease in effectiveness 24 .","[4.0, 4.0, 4.0, 4.0]",Biology,train,4.0,tweets,961986502103392256
10.1073/pnas.1318978111,Biology_tweet_140,Female fertility: What's testosterone got to do with it?  The paper: ,"Finally, we report that low doses of exogenous androgens enhance gonadotropin-induced ovulation in mice, further demonstrating the critical role that androgens play in follicular development and fertility.",Female fertility: What's testosterone got to do with it?  The paper: ,"Interestingly, we find that the scaffold molecule paxillin regulates both processes, making it a critical regulator of AR actions in the ovary. Finally, we report that low doses of exogenous androgens enhance gonadotropin-induced ovulation in mice, further demonstrating the critical role that androgens play in follicular development and fertility. These data may explain reported positive effects of androgens on ovulation rates in women with diminished ovarian reserve.","[3.0, 4.0, 3.0, 2.0]",Biology,train,3.0,tweets,441145516475162625
10.1038/s41396-018-0222-x,Biology_tweet_141,"Microbial community structure predicted by the stable marriage problem. (arXiv:1712.06042v1 [q-bio.PE])

Experimental","That is to say, given its microbial partners, there is no need for a microbe to retain metabolic pathways utilizing nutrients which it never gets to use in any of the ""stable marriages"".","Microbial community structure predicted by the stable marriage problem. (arXiv:1712.06042v1 [q-bio.PE])

Experimental","An intriguing possibility is that the evolutionary trajectory of each species may be shaped by its partners in the SMP. That is to say, given its microbial partners, there is no need for a microbe to retain metabolic pathways utilizing nutrients which it never gets to use in any of the ""stable marriages"". Over evolutionary time, such unused pathways would be dropped from its genome.","[3.0, 3.0, 3.0, 4.0]",Biology,train,3.25,tweets,942937962928422917
10.1002/etc.2793,Biology_tweet_142,"Metformin, a common antidiabetic drug, acts as endocrine disrupter in fish  (Env. Tox. Chem. paywall, sorry)",Metformin was below the limit of detection in control samples and was found at 41 AE 8 mg/L in treatment samples.,"Metformin, a common antidiabetic drug, acts as endocrine disrupter in fish  (Env. Tox. Chem. paywall, sorry)",The link between insulin signaling and steroidogenesis indicates the potential for antidiabetic drugs including metformin to act as endocrine disruptors. Metformin was below the limit of detection in control samples and was found at 41 AE 8 mg/L in treatment samples. No differences in expression were found in the liver between treatment or sex for the metabolic genes GK (2-way ANOVA:,"[2.0, 3.0, 2.0, 2.0]",Biology,train,2.25,tweets,593297064592863233
10.1038/ncomms4406,Biology_tweet_143,BELGIUM: Fullerene-free organic solar cells reaches 8.4% efficiency through multilayer cascade structures ,"However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors.",BELGIUM: Fullerene-free organic solar cells reaches 8.4% efficiency through multilayer cascade structures ,"These results confirm that multilayer cascade structures are a promising alternative to conventional donor-fullerene organic solar cells. However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors. 17) , which is comparable to the best bilayer SubPc/C 60 cells reported in the literature 19 .","[2.0, 2.0, 3.0, 3.0]",Biology,train,2.5,tweets,443419835804827648
10.1038/s41467-018-06157-6,Biology_tweet_145,The paper is out!  Figures that show #geographic #climatic #phylogenetic patterns of #amphibian species richness in the #US.  An awesome #groupeffort thanks to USGS_ARMI and lead author @username.  #Scientists spent a week @username.  ,"While we demonstrate that amphibian communities are sensitive to changes in climate, our results suggest that changing climate is not the proximate cause for ongoing assemblage-wide declines that have been observed in North American amphibians.",The paper is out!  Figures that show #geographic #climatic #phylogenetic patterns of #amphibian species richness in the #US.  An awesome #groupeffort thanks to USGS_ARMI and lead author @username.  #Scientists spent a week @username.  ,"For example, we found that summer drought has the strongest impact in warm and dry regions, decreased snowfall has a smaller effect in eastern compared to western North America, and winter warming is predicted to decrease species richness for all species groups except tree frogs. While we demonstrate that amphibian communities are sensitive to changes in climate, our results suggest that changing climate is not the proximate cause for ongoing assemblage-wide declines that have been observed in North American amphibians. Instead, we find that recent change in climate is a strong predictor of why local species richness is declining more quickly in some regions and that positive effects of climate may be buffering declines in other regions.","[3.0, 3.0, 2.0, 5.0, 3.0]",Biology,train,3.2,tweets,1044950968985636864
10.1016/j.devcel.2014.11.012,Biology_tweet_146,Senescent cells accelerate wound closure via PDGF-AA secretion from Campisi&amp;co of @username ,"Notably, senescent cells were present only transiently during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues.",Senescent cells accelerate wound closure via PDGF-AA secretion from Campisi&amp;co of @username ,"In contrast to the well-documented deleterious effects of senescent cells and the SASP, the results presented here unambiguously demonstrate a positive role for senescent cells and the SASP in tissue repair. Notably, senescent cells were present only transiently during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues. Moreover, PDGF-A was induced very early upon senescence induction in cell culture, suggesting the time-dependent regulation of SASP factors might in part explain the beneficial versus deleterious effects of senescent cells.","[2.0, 4.0, 3.0]",Biology,train,3.0,tweets,543089204616785920
10.1038/ncomms7310,Biology_tweet_147,Again our researchers create impact in photonics via @username . Frequency combs in a silcon nanophotonic wire. ,Silicon nanophotonic wire waveguides can be engineered 17 within a nanometre precision in a standard CMOS facility.,Again our researchers create impact in photonics via @username . Frequency combs in a silcon nanophotonic wire. ,"This aberration increases the conversion of parasitic processes significantly 12 and makes modelling difficult. Silicon nanophotonic wire waveguides can be engineered 17 within a nanometre precision in a standard CMOS facility. Such waveguides offer many advantages for mid-infrared nonlinear optics, mostly related to the wide transparency range of silicon (1.1-8 mm), its high nonlinear refractive index, the possibility of precise dispersion engineering of the waveguide platforms and the high refractive index contrast between the silicon waveguide core and the cladding material (typically, SiO 2 or air), which allows for densely integrated waveguide systems with a nonlinear parameter one to two orders of magnitude higher than that possible in the chalcogenide or silicon nitride systems.","[3.0, 3.0, 4.0, 1.0, 3.0]",Biology,train,2.8,tweets,569786392999563264
10.1038/s41467-019-10373-z,Biology_tweet_15,"In our latest article, just out in @username  we found that &lt;0.1% of fungi, mostly belonging to Ascomycota, dominate soils globally. We mapped their global distribution and found that contain multiple genes related to stress-tolerance &amp; resource uptake ","Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonising a wide range of environments.","In our latest article, just out in @username  we found that &lt;0.1% of fungi, mostly belonging to Ascomycota, dominate soils globally. We mapped their global distribution and found that contain multiple genes related to stress-tolerance &amp; resource uptake ","Our findings indicate that 83 phylotypes (<0.1% of the retrieved fungi), mostly belonging to wind dispersed, generalist Ascomycota, dominate soils globally. Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonising a wide range of environments. Our findings constitute a major advance in our understanding of the ecology of fungi, and have implications for the development of strategies to preserve them and the ecosystem functions they provide.","[3.0, 4.0, 4.0]",Biology,train,3.6666666666666665,tweets,1134024517695758336
10.1210/en.2015-2036,Biology_tweet_150,"Of mice and women. Vitamin D suppls inhibits tumour-gene Id1 in breast cancer, slows growth. Deficiency accelerates ","We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression.","Of mice and women. Vitamin D suppls inhibits tumour-gene Id1 in breast cancer, slows growth. Deficiency accelerates ","Further, we discovered that attenuated vitamin D signaling due to Vdr ablation enhances tumor progression and, importantly, is sufficient to enable metastases, which are the primary cause of treatment failure and death for patients with BCa. We also discovered that, although circulating 25(OH)D has many systemic effects (1), a critical mechanism for vitamin D signaling to inhibit BCa progression is a tumor autonomous activity that suppresses Id1 expression. Interestingly, Sherman et al found a tumor cell nonautonomous mechanism for VDR signaling to inhibit pancreatic ductal adenocarcinoma progression and Fernandez-Garcia et al found that calcitriol induces, rather than inhibits, Id1 expression in a colon carcinoma cell line.","[3.0, 4.0, 3.0, 4.0]",Biology,train,3.5,tweets,708025691305070593
10.1111/1755-0998.12987,Biology_tweet_151,"Environmental DNA for the enumeration and management of Pacific #Salmon

Researchers show daily, and near‐daily, flow‐corrected eDNA rate closely tracks daily numbers of returning sockeye and coho spawners and outmigrating sockeye smolts

#fishsci  ","Because the concentration of eDNA in streamwater results from both the amount of DNA shed by organisms and the flow of water, the product of eDNA concentration and streamflow (measured in units of water volume per time) can be used to calculate absolute quantities of eDNA per unit time.","Environmental DNA for the enumeration and management of Pacific #Salmon

Researchers show daily, and near‐daily, flow‐corrected eDNA rate closely tracks daily numbers of returning sockeye and coho spawners and outmigrating sockeye smolts

#fishsci  ","than simply accumulating as fish enter a watershed, eDNA concentrations might spike up and down as a pulse of fish swims past a sampling point, with the size of the spike correlated with fish number and/or biomass. Because the concentration of eDNA in streamwater results from both the amount of DNA shed by organisms and the flow of water, the product of eDNA concentration and streamflow (measured in units of water volume per time) can be used to calculate absolute quantities of eDNA per unit time. If, for instance, juveniles rear sufficiently far upstream, the signal of their eDNA should be weak or undetectable, eliminating a source of noise that would prevent the robust enumeration of adult salmon entering lower stream reaches with eDNA.","[3.0, 2.0, 4.0, 2.0]",Biology,train,2.75,tweets,1080984404086964224
10.1016/j.ccell.2015.05.009,Biology_tweet_152,"Wang, Shih @username &amp; co Inhibition of SYK sensitizes ovarian cancer to paclitaxel  ","We found that SYK inhibitors stabilized microtubules through dephosphorylation of microtubule and microtubule-associated proteins, a mechanism that is distinct from paclitaxel.","Wang, Shih @username &amp; co Inhibition of SYK sensitizes ovarian cancer to paclitaxel  ","Importantly, inhibition of SYK sensitizes ovarian cancer cells to paclitaxel treatment via enhancing microtubule stability. We found that SYK inhibitors stabilized microtubules through dephosphorylation of microtubule and microtubule-associated proteins, a mechanism that is distinct from paclitaxel. As a result, SYK inhibitor and paclitaxel formed a synergistic cytotoxic effect in tumor cells, especially in those that were paclitaxel-resistant.","[2.0, 1.0, 2.0, 3.0]",Biology,train,2.0,tweets,611837874909126656
10.1038/s41467-018-07600-4,Biology_tweet_153,"Congratulations to Junwei, my dear friends first paper was just published. They discovered that magic cluster do also appear for hard sphere systems. Even more ground breaking: is systems of thousands of Colloids. Also a highly interesting reviewer 3 /1

 ",This raises the fundamental question of whether some colloidal cluster sizes are thermodynamically preferred over others.,"Congratulations to Junwei, my dear friends first paper was just published. They discovered that magic cluster do also appear for hard sphere systems. Even more ground breaking: is systems of thousands of Colloids. Also a highly interesting reviewer 3 /1

 ","While the dominant occurrence of atomic clusters with magic numbers in mass spectra 4 suggests self-adjustment in their sizes during formation by addition or removal of atoms to reach magic numbers under appropriate circumstances, the number of particles in a colloidal cluster remains fixed in confinement, which allows experiments to explore clusters of arbitrary sizes. This raises the fundamental question of whether some colloidal cluster sizes are thermodynamically preferred over others. Here, we demonstrate that the magic number phenomenon known from atomic clusters extends to the colloidal realm.","[3.0, 4.0, 2.0, 3.0, 1.0]",Biology,train,2.6,tweets,1072481213540167682
10.1111/ele.12236,Biology_tweet_154,"Connectance of mutualistic networks increases persistance to disturbance, but result in global community collapse: ",The extent to which pollinators interact with the same plant species increases with connectance and/or nestedeness.,"Connectance of mutualistic networks increases persistance to disturbance, but result in global community collapse: ",Our results can be understood intuitively by considering the 'net effects' of species on each other and the way in which these effects are mediated by the topology of mutualistic networks. The extent to which pollinators interact with the same plant species increases with connectance and/or nestedeness. A high nestedness of the mutualistic network may therefore promote the occurrence of indirect positive effects between pollinators.,"[2.0, 2.0, 1.0, 3.0]",Biology,train,2.0,tweets,430638501558620161
10.1038/s41467-018-07273-z,Biology_tweet_155,"Our 1st paper ( showing #heatwave damage to #male #reproduction &amp; #sperm in a #insect model; out in @username! Thanks to @username @username @username @username Matt D, Aly L, Lukasz M, Laura H &amp; Paul T. 🌞🐞 @username @username @username. ","Sons of males that had been exposed to a single heatwave in the previous generation showed a 25% reduction in mating success and subsequent offspring production, compared with controls whose fathers had not experienced heatwave conditions ( Fig.","Our 1st paper ( showing #heatwave damage to #male #reproduction &amp; #sperm in a #insect model; out in @username! Thanks to @username @username @username @username Matt D, Aly L, Lukasz M, Laura H &amp; Paul T. 🌞🐞 @username @username @username. ","4c, d , e, f). Sons of males that had been exposed to a single heatwave in the previous generation showed a 25% reduction in mating success and subsequent offspring production, compared with controls whose fathers had not experienced heatwave conditions ( Fig. Critically, these same transgenerational effects were also evident when mature inseminated sperm alone had experienced the same conditions within the female: sons fertilised by heatwave-exposed spermatozoa in the female tract suffered 25 to 40% reductions in their reproductive output and mating success, compared with sons from parents where the mother had experienced the heatwave before mating and sperm storage, or controls where no heatwaves were experienced ( Fig.","[3.0, 4.0, 3.0, 4.0, 4.0]",Biology,train,3.6,tweets,1062319307084980224
10.1016/j.cmet.2015.02.003,Biology_tweet_16,'Salt on Our Skin' Cutaneous Na Storage Strengthens the Antimicrobial Barrier Function &amp;  Boosts Macrophage-driven.. ,"Finally, we found that increasing Na + content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense.",'Salt on Our Skin' Cutaneous Na Storage Strengthens the Antimicrobial Barrier Function &amp;  Boosts Macrophage-driven.. ,"This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control. Finally, we found that increasing Na + content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense. We suggest that the hypertonic microenvironment could serve as a barrier to infection.","[4.0, 4.0, 4.0]",Biology,train,4.0,tweets,572822414125608961
10.1016/j.neuron.2014.05.028,Biology_tweet_160,"See paper by Ressler and colleagues on Tac2, NkB &amp; Nk3 Receptor in Fear Memory Consolidation ","However, this does not preclude the hypothesis that different fear paradigms might reveal a role of Tac2 in the amygdala in contextual fear conditioning.","See paper by Ressler and colleagues on Tac2, NkB &amp; Nk3 Receptor in Fear Memory Consolidation ","Interestingly, in our fear paradigm, the Tac2 gene within the amygdala is involved in auditory (CS+US paired) but not stress or contextual memories (US only). However, this does not preclude the hypothesis that different fear paradigms might reveal a role of Tac2 in the amygdala in contextual fear conditioning. Thus, we believe that enhanced Tac2 gene expression in our fear models enhanced NkB production in the amygdala, binding to Nk3R and promoting fear memory consolidation.","[3.0, 4.0, 2.0]",Biology,train,3.0,tweets,489475682549137408
10.1002/ece3.3060,Biology_tweet_161,"New paper, led by @username, on how breeding phenology affects genetic structure of 4 pond-breeding #salamanders ","Similarly, observed that the fall breeding A. opacum has stronger genetic differentiation than A. maculatum among the same ponds in Massachusetts.","New paper, led by @username, on how breeding phenology affects genetic structure of 4 pond-breeding #salamanders ","In Missouri, found that the fall breeding A. annulatum had higher levels of genetic differentiation than the spring breeding A. maculatum on the same landscape. Similarly, observed that the fall breeding A. opacum has stronger genetic differentiation than A. maculatum among the same ponds in Massachusetts. From an evolutionary standpoint, the observed differences in dispersal distances and genetic structure between fall breeding and spring breeding species may be a result of the trade-off between larval period length and size at metamorphosis .","[3.0, 3.0, 3.0, 3.0, 2.0]",Biology,train,2.8,tweets,867064003952095235
10.1016/j.cell.2018.04.038,Biology_tweet_163,4.8Å structure of Telomerase bound to Telomeric DNA from the labs of Juli Feigon and Hong Zhou in @username  ,"We tried to add detergent to the sample in order to reduce exposure of particles to hydrophobic environment; however, there were very few particles in holes of cryo-EM grids in the presence of detergent (0.025% IGEPAL CA-630), suggesting that telomerase holoenzyme has affinity for the hydrophobic air/ water interface.",4.8Å structure of Telomerase bound to Telomeric DNA from the labs of Juli Feigon and Hong Zhou in @username  ,"This highly purified sample showed relatively good homogeneity of particles with a uniform shape in our negative stain EM images, but very high heterogeneity in our cryo-EM images. We tried to add detergent to the sample in order to reduce exposure of particles to hydrophobic environment; however, there were very few particles in holes of cryo-EM grids in the presence of detergent (0.025% IGEPAL CA-630), suggesting that telomerase holoenzyme has affinity for the hydrophobic air/ water interface. Bacitracin can partially mimic detergent to protect exposure of telomerase particles to the air/water interface while keeping a sufficient number of particles in the holes of cryo-EM grids for data collection.","[1.0, 1.0, 2.0, 2.0, 2.0]",Biology,train,1.6,tweets,1002669115335573504
10.1038/s41467-018-07557-4,Biology_tweet_165,New paper from @username about the impact of thawing permafrost on infrastructure across the entire Arctic. Congrats @username et al.! ,"In an engineering context, the selected threshold is conservative because infrastructure (e.g., buildings) could experience thaw settlements and failure before the thaw of near-surface permafrost.",New paper from @username about the impact of thawing permafrost on infrastructure across the entire Arctic. Congrats @username et al.! ,"The ensemble model provided accurate predictions of the observed ground temperatures retrospectively, indicating potential for good performance in prognostic studies 23 . In an engineering context, the selected threshold is conservative because infrastructure (e.g., buildings) could experience thaw settlements and failure before the thaw of near-surface permafrost. However, a conservative threshold is justified considering the use of statistically based methodology in modelling of the ground thermal regime (Methods).","[2.0, 3.0, 2.0, 2.0]",Biology,train,2.25,tweets,1072542870219952128
10.1111/1365-2656.12871,Biology_tweet_166,"Our paper on disentangling disease dynamics of #rabbit haemorrhagic disease virus and #myxoma virus in Australia now online in Journal of Animal Ecology!
  
  with @username, @username, @username, @username","The threat of diseases to wildlife populations, and the efficiency of pathogens as biocontrol agents, can only be evaluated with an adequate understanding of how different components F I G U R E 2 Estimated average changes in monthly survival rates of rabbits in different disease states, namely (i) susceptible to rabbit haemorrhagic disease virus (RHDV) and immune to myxoma virus (MYXV) (red bars), (ii) susceptible to MYXV and immune to RHDV (blue bars), (iii) susceptible to both RHDV and MYXV (green bars) and (iv) young rabbits <90 days old of various disease states, including individuals with maternal antibodies against RHDV and/ or MYXV (purple bars).","Our paper on disentangling disease dynamics of #rabbit haemorrhagic disease virus and #myxoma virus in Australia now online in Journal of Animal Ecology!
  
  with @username, @username, @username, @username","Capture rates in most capture sessions were <40% and varied over time (Supporting Information Figure S9 ), likely explaining why uncertainty in the estimates of individual disease states and the time-specific disease effect on rabbit survival led to large credible intervals. The threat of diseases to wildlife populations, and the efficiency of pathogens as biocontrol agents, can only be evaluated with an adequate understanding of how different components F I G U R E 2 Estimated average changes in monthly survival rates of rabbits in different disease states, namely (i) susceptible to rabbit haemorrhagic disease virus (RHDV) and immune to myxoma virus (MYXV) (red bars), (ii) susceptible to MYXV and immune to RHDV (blue bars), (iii) susceptible to both RHDV and MYXV (green bars) and (iv) young rabbits <90 days old of various disease states, including individuals with maternal antibodies against RHDV and/ or MYXV (purple bars). We show that despite a strongly seasonal force of infection (FoI) for RHDV and MYXV, it is likely that susceptible rabbits can be infected (at least at low levels) throughout the year, having implications for rabbit conservation and biocontrol.","[4.0, 4.0, 4.0, 3.0, 2.0]",Biology,train,3.4,tweets,1016577491194933248
10.1038/nature12167,Biology_tweet_168,First ever class F GPCR structure:  human SMO receptor with antagonist (via @username @username @username),"The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity.",First ever class F GPCR structure:  human SMO receptor with antagonist (via @username @username @username),"In cilia, the activated SMO receptor induces the modification of GLI transcription factors into the active form, thereby inhibiting the processing of GLI transcription factors into a repressor form. The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity. Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration .","[1.0, 2.0, 2.0, 2.0]",Biology,train,1.75,tweets,330273869644578818
10.1126/scitranslmed.aau6246,Biology_tweet_17,"The PSEN1 inhibitor MRK-560 can target NOTCH1-mutant T-ALL, according to preclinical research. MRK-560 decreased proliferation in T-ALL cell lines and reduced #leukemia burden and increased survival in mouse models of NOTCH1-mutant T-ALL. #leusm ","MRK-560 treatment significantly reduced leukemia burden compared to vehicle-treated mice, as assessed by peripheral blood counts of human CD45 + cells and in vivo bioluminescence (P ≤ 0.01) (Fig.","The PSEN1 inhibitor MRK-560 can target NOTCH1-mutant T-ALL, according to preclinical research. MRK-560 decreased proliferation in T-ALL cell lines and reduced #leukemia burden and increased survival in mouse models of NOTCH1-mutant T-ALL. #leusm ","*P ≤ 0.05, ***P ≤ 0.001. MRK-560 treatment significantly reduced leukemia burden compared to vehicle-treated mice, as assessed by peripheral blood counts of human CD45 + cells and in vivo bioluminescence (P ≤ 0.01) (Fig. The various degrees of response to MRK-560 treatment were not explained by differences in PSEN1 expression in the PDX models ( fig.","[5.0, 4.0, 3.0, 4.0]",Biology,train,4.0,tweets,1133808943933861890
10.1098/rsos.171474,Biology_tweet_170,"Interesting article on violent video games not linked to teen aggression. @username you might be interested in this 
While games can cause frustration and anger, playing video games doesn't lead to aggression in every day life.

",The semi-partial effect relating violent gaming to aggressive behaviour was r ¼ 0.01.,"Interesting article on violent video games not linked to teen aggression. @username you might be interested in this 
While games can cause frustration and anger, playing video games doesn't lead to aggression in every day life.

","larger) to findings present in the existing literature , and in line with proposed minimum practical media effect sizes [72] . The semi-partial effect relating violent gaming to aggressive behaviour was r ¼ 0.01. Further, we derived a 95% coincidence interval around this point estimate that ranged from 20.08 to 0.10 using a bootstrapping approach with 10 000 iterations.","[4.0, 4.0, 3.0, 3.0]",Biology,train,3.5,tweets,1095653544047169538
10.1098/rsos.180695,Biology_tweet_171,"What can we learn about the origins of humanity from our use of air conditioning? An article in our journal, #OpenScience, maps our preferences over global climate data and discovers that humans prefer the climate of west central Kenya
 ","When humans adjust the climates within their homes, it is unlikely that most are consciously attempting to emulate the climatic conditions of some outdoor location in another country or continent.","What can we learn about the origins of humanity from our use of air conditioning? An article in our journal, #OpenScience, maps our preferences over global climate data and discovers that humans prefer the climate of west central Kenya
 ","The mean vapour pressure was 12.58 hPa for North American homes and was similar to the outdoor conditions in west central Kenya (12.96 hPa). When humans adjust the climates within their homes, it is unlikely that most are consciously attempting to emulate the climatic conditions of some outdoor location in another country or continent. Instead, they are almost certainly attempting to achieve climatic conditions that result in thermal comfort.","[2.0, 2.0, 2.0]",Biology,train,2.0,tweets,1108684701177430016
10.3945/jn.113.188441,Biology_tweet_173,Uh oh.  instant #ramen linked to #metabolic syndrome.  ,"The consumption of instant noodles was associated with increased prevalence of metabolic syndrome in women, independent of major dietary patterns.",Uh oh.  instant #ramen linked to #metabolic syndrome.  ,"The 2 major dietary patterns were associated with distinct cardiometabolic risk factors. The consumption of instant noodles was associated with increased prevalence of metabolic syndrome in women, independent of major dietary patterns. The prevalence of overweight in the adult population increased from 26% in 1998 to 32% in 2007 (1) and that of metabolic syndrome in the adult population increased from 25% to 31% in the same time period .","[4.0, 3.0, 3.0, 4.0]",Biology,train,3.5,tweets,531556799586254849
10.3945/jn.113.188441,Biology_tweet_174,Instant noodle intake and cardiometabolic risk factors - PubMed - NCBI  ,"Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women.",Instant noodle intake and cardiometabolic risk factors - PubMed - NCBI  ,"Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men. Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women. Analysis adjusting for this pattern did not change associations between instant noodle intake and metabolic syndrome and abdominal obesity in women.","[3.0, 3.0, 1.0, 4.0]",Biology,train,2.75,tweets,539508237326774273
10.1038/s41467-019-09113-0,Biology_tweet_175,"How can we quantitatively compare #geophysical and #geochemical data along #volcanic arcs? New research published in @username today by Till and co-authors propose an exciting new method to assess volcanic variability along the Cascades 

 ","Given the unlikelihood of >80-90% crystallization producing the erupted compositions in nature, we also calculate a more realistic scenario in which magmas are produced by a mixture of the two end member processes with 60% of crystallization and the remainder through crustal melting.","How can we quantitatively compare #geophysical and #geochemical data along #volcanic arcs? New research published in @username today by Till and co-authors propose an exciting new method to assess volcanic variability along the Cascades 

 ","The volume and composition of material erupted at Newberry and Three Sisters region (latitudes 43.5-44.5°N) requires a different balance between crystallization and crustal melting, as 60% crystallization does not release enough heat to produce the remainder of magmas through crustal melting. Given the unlikelihood of >80-90% crystallization producing the erupted compositions in nature, we also calculate a more realistic scenario in which magmas are produced by a mixture of the two end member processes with 60% of crystallization and the remainder through crustal melting. The results along the Cascades volcanic arc are constrained as part of an inversion over the broader Cascadia region.","[2.0, 4.0, 3.0, 1.0]",Biology,train,2.5,tweets,1109063943023153153
10.1038/s41467-019-09863-x,Biology_tweet_178,"Study finds combined #permafrost melt and #albedo feedbacks in #Arctic will contribute more than expected to #climatechange. Based on current #ParisAgreement pledges predicted warming will cost $67 trillion to global economy. #ClimateAction #geog2661
 ","The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 .","Study finds combined #permafrost melt and #albedo feedbacks in #Arctic will contribute more than expected to #climatechange. Based on current #ParisAgreement pledges predicted warming will cost $67 trillion to global economy. #ClimateAction #geog2661
 ","To put this number into context, it exceeds the estimated long-term gains from economic development in the Arctic region through transit shipping routes 52 and mineral resource extraction 53 under high emissions scenarios by around 10 times, and could also dwarf pan-Arctic damages to infrastructure from thawing permafrost 55 . The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 . Robustness of the estimates for the PCF and SAF effects.","[2.0, 2.0, 4.0]",Biology,train,2.6666666666666665,tweets,1120639268177829888
10.1186/gb-2013-14-7-r73,Biology_tweet_18,Very long intergenic RNAs (vlincRNAs) cover 10% of our genome and are frequently regulated by endogenous retroviruses ,"VlincRNAs were found in all cell lines tested, including non-cancerous cell lines and tissues (Table 1) .",Very long intergenic RNAs (vlincRNAs) cover 10% of our genome and are frequently regulated by endogenous retroviruses ,"Overall, 341 of the original 580 tumor vlincRNAs ( Table 1) overlap ENCODE vlincRNAs identified from mostly different cell lines, using a different sequencing platform (p-value 1.54 × 10 -45 ). VlincRNAs were found in all cell lines tested, including non-cancerous cell lines and tissues (Table 1) . Embryonic stem cell line H1-hEsc expressed 469 such regions, while non-cancerous normal human epidermal keratinocyte line (NHEK) and normal human umbilical vein endothelial cells (HUVEC) expressed 248 and 340 vlincRNAs, respectively (Table 1; Additional File 1,  Table S1 ).","[2.0, 2.0, 2.0]",Biology,train,2.0,tweets,360419829343199235
10.1016/j.cell.2013.08.004,Biology_tweet_181,Sic1 makes sick in a new time zone: pill for jet lag not far  @username @username @username @username,"As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing.",Sic1 makes sick in a new time zone: pill for jet lag not far  @username @username @username @username,"Critically, we show that knockdown of Sik1 within the SCN results in extended light-induced phase shifts and an enhanced rate of re-entrainment to an advanced LD cycle. As SIK1 acts to suppress the effects of light on the clock, this pathway provides a pharmacological target for the treatment of disturbed circadian rhythms, including jet lag, shift-work, and illnesses that disturb circadian timing. Surprisingly, the majority (81%, 436 genes) of transcripts were downregulated in response to light, with a smaller number of genes showing upregulation (19%, 100 genes).","[4.0, 2.0, 3.0, 5.0]",Biology,train,3.5,tweets,376331239868751872
10.1016/j.cell.2016.04.014,Biology_tweet_182,#ILCs as #ImmuneSentinels | Human ILC-Th counterparts | Colonna &amp; Oltz @username @username  ,"In contrast to mice, which express Il17 in both Th17s and a subset of ILC3s, humans express these cytokines only in Th17s (Figure 1E) .",#ILCs as #ImmuneSentinels | Human ILC-Th counterparts | Colonna &amp; Oltz @username @username  ,"We also identified an SE in Th17 cells that spanned its signature IL17A/IL17F cytokine locus, as well as the neighboring MCM3 gene, which is expressed in all cell types ( Figure 5C ). In contrast to mice, which express Il17 in both Th17s and a subset of ILC3s, humans express these cytokines only in Th17s (Figure 1E) . Only a subset of enhancers active in Th17s were in regions of high sequence conservation, perhaps reflecting evolutionary revisions to the regulatory landscape of this locus that endow Th17-specific expression in humans.","[2.0, 2.0, 1.0, 2.0, 2.0]",Biology,train,1.8,tweets,728652449200766976
10.1038/s41467-018-04863-9,Biology_tweet_183,"Casaccia  and colleagues characterise role of PRMT5 in regulation of developmental myelination
@username @username

 ","PRMT5 pharmacological inhibition, CRISPR/cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation.","Casaccia  and colleagues characterise role of PRMT5 in regulation of developmental myelination
@username @username

 ","PRMT5 pharmacological inhibition, CRISPR/cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation. Conditional ablation of Prmt5 in progenitors results in hypomyelination, reduced survival and differentiation. Decreased histone H4R3 symmetric methylation is followed by increased nuclear acetylation of H4K5, and is rescued by pharmacological inhibition of histone acetyltransferases.","[5.0, 2.0, 3.0, 2.0]",Biology,train,2.0,tweets,1021765418653032448
10.1038/s41467-019-09945-w,Biology_tweet_184,"New paper in @username explores the contribution of 6 socioeconomic drivers (population, economic growth, diets, ag productivity, land-use regulation, and trade) in future land-use projections. Check it out at:   @username @username",Yield increase is therefore shown to be more effective in reducing land use when combined with land-use regulation and consumption changes.,"New paper in @username explores the contribution of 6 socioeconomic drivers (population, economic growth, diets, ag productivity, land-use regulation, and trade) in future land-use projections. Check it out at:   @username @username","Furthermore, this study adds an analysis of interactions between factors: an increase in agricultural efficiency can reduce demand for cropland but can also trigger higher demand. Yield increase is therefore shown to be more effective in reducing land use when combined with land-use regulation and consumption changes. Consumption changes, better land management, and increased agricultural productivity therefore appear robust and effective measures to reduce the demand for agricultural land, in particular when bundled together.","[4.0, 2.0, 3.0, 2.0, 2.0]",Biology,train,2.6,tweets,1128819746214821888
10.1186/1471-2164-15-599,Biology_tweet_186,Human adaptive evolution found using #compara and #BioMart #CitedEnsembl @username ,"Taken together, our results strongly indicate that positive selection in neural genes is likely to have played a significant role in the human evolution.",Human adaptive evolution found using #compara and #BioMart #CitedEnsembl @username ,"None of these classes achieved statistical significance, except synapse in the accelerated gene set, with five observed genes compared to one expected by chance (proportion test, p < 10 −3 ). Taken together, our results strongly indicate that positive selection in neural genes is likely to have played a significant role in the human evolution. Comparing the number of non-synonymous and synonymous substitutions in sister species can help identify sequences that have been the target of positive selection in one of the species.","[3.0, 4.0, 3.0, 3.0]",Biology,train,3.25,tweets,492585813897916416
10.1038/s41467-018-04627-5,Biology_tweet_187,Educators are the frontline of creating permanent brain changes.  Classrooms are where education and neuroscience meet. @username @username @username @username @username @username @username @username @username ,Widespread changes in the white matter track learning.,Educators are the frontline of creating permanent brain changes.  Classrooms are where education and neuroscience meet. @username @username @username @username @username @username @username @username @username ,"Motion and Reading Skill were unrelated (r(97) = 0.13, p = 0.19). Widespread changes in the white matter track learning. The AF and ILF connect distinct components of the reading circuitry and are thought to carry signals that contribute uniquely to the reading process 48 .","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,tweets,1005593985451220994
10.1126/scitranslmed.aaa8419,Biology_tweet_188,An unexpected microbe (Ureaplasma species) is killing lung transplant patients  see more ,We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum.,An unexpected microbe (Ureaplasma species) is killing lung transplant patients  see more ,"This patient was shown to have systemic M. hominis infection . We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum. On postoperative day 12, he developed mental status changes, and his ammonia concentration was 549 mM.","[4.0, 3.0, 1.0, 1.0]",Biology,train,2.0,tweets,591218843336474624
10.1098/rsbl.2014.0993,Biology_tweet_189," 
First evidence of Circa-lunar Cycle in Ephedra!! @username @username",To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations .," 
First evidence of Circa-lunar Cycle in Ephedra!! @username @username","The full moon is thus important for efficient pollination of E. foeminea both for pollinator navigation in the dark and for attraction to the cones. To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations . By contrast, we find no correlation between the phases of the moon and secretion of pollination drops in the sympatric but wind-pollinated E. distachya ( figure 2b) ).","[5.0, 1.0, 3.0, 2.0]",Biology,train,2.0,tweets,583554691902087169
10.1073/pnas.1515733112,Biology_tweet_190,Stress response modulation by mitochondria [Genetics]   @username,"We show that mitochondrial dysfunctions altered the hypothalamicpituitary-adrenal axis, sympathetic adrenal-medullary activation and catecholamine levels, the inflammatory cytokine IL-6, circulating metabolites, and hippocampal gene expression responses to stress.",Stress response modulation by mitochondria [Genetics]   @username,"This work shows that mitochondria can regulate complex whole-body physiological responses, impacting stress perception at the cellular and organismal levels. We show that mitochondrial dysfunctions altered the hypothalamicpituitary-adrenal axis, sympathetic adrenal-medullary activation and catecholamine levels, the inflammatory cytokine IL-6, circulating metabolites, and hippocampal gene expression responses to stress. Each mitochondrial defect generated a distinct whole-body stressresponse signature.","[5.0, 5.0, 4.0]",Biology,train,4.666666666666667,tweets,671832037129641984
10.1073/pnas.1402074111,Biology_tweet_191,Epitopes on the MERS COV spike protein. Important info for monitoring virus changes. ,"At concentrations ≥20 μg/mL, six of seven scFvFcs neutralized MERS-CoV completely (Fig.",Epitopes on the MERS COV spike protein. Important info for monitoring virus changes. ,"The other three scFvFcs, 1E9, M14D3, and 1F8, neutralized the virus with IC values of 3.21, 4.3, and 6.27 μg/mL, respectively (Table S1 ). At concentrations ≥20 μg/mL, six of seven scFvFcs neutralized MERS-CoV completely (Fig. Three IgG1 Abs also were tested for live virus neutralization; 3B11 had a lower IC value than 1F8 and 3A1 IgGs (Table S1 ).","[4.0, 2.0, 1.0, 2.0, 2.0]",Biology,train,2.2,tweets,461028054945775616
10.1016/j.ebiom.2017.03.046,Biology_tweet_192,"The #epigenetic clock is a better index for biological #age than #telomere length, transcriptome or metabolome ","Moreover, data also suggest that most of the biological age predictors we have discussed have little or no interaction with each other.","The #epigenetic clock is a better index for biological #age than #telomere length, transcriptome or metabolome ","Additional longitudinal data are necessary to further confirm the causal nature. Moreover, data also suggest that most of the biological age predictors we have discussed have little or no interaction with each other. Thus, effects are independent of each other and may therefore be describing different parts of the aging process.","[3.0, 2.0, 3.0, 3.0]",Biology,train,2.75,tweets,851349900793131008
10.1038/s41467-018-06041-3,Biology_tweet_193,Staufen1 is a potential therapeutic target in spinocerebellar ataxia type 2 ,"The strength of protein-protein interaction did not differ for wild-type and mutant ATXN2, and we found co-localization of STAU1 with ATXN2 aggregates in individuals with SCA2 and in an SCA2 mouse model (Fig.",Staufen1 is a potential therapeutic target in spinocerebellar ataxia type 2 ,"Here, we show for the first time that STAU1 is a novel RNAdependent interactor for ATXN2 (Fig. The strength of protein-protein interaction did not differ for wild-type and mutant ATXN2, and we found co-localization of STAU1 with ATXN2 aggregates in individuals with SCA2 and in an SCA2 mouse model (Fig. We showed increased STAU1 levels in SCA2-FBs and LBCs, SCA2 mouse cerebellar extracts, and in ALS cells expressing mutant TDP-43 (Fig.","[1.0, 1.0, 5.0, 1.0]",Biology,train,1.0,tweets,1039082223973146624
10.1016/j.cub.2017.12.015,Biology_tweet_194,"Learning in mosquitoes:
","This choice is not random; most mosquitoes specialize in one or a few vertebrate host species, and some individuals in a host population are preferred over others.","Learning in mosquitoes:
","This choice is not random; most mosquitoes specialize in one or a few vertebrate host species, and some individuals in a host population are preferred over others. Here, we show that olfactory learning may contribute to Aedes aegypti mosquito biting preferences and host shifts. Using pharmacological interventions, RNAi, and CRISPR gene editing, we found that modification of the dopamine-1 receptor suppressed their learning abilities.","[2.0, 5.0, 5.0, 3.0]",Biology,train,3.0,tweets,960285664100143104
10.1038/s41598-018-28950-5,Biology_tweet_195,"#Evaluation of in vitro neuronal platforms as surrogates #for in vivo whole brain systems

Submission open for coming issue@
 ","Furthermore, neuronal cultures, in contrast to brain slices cultured on MEAs, are more readily adapted to human-relevant systems by utilizing either human primary or stem-cell derived neurons.","#Evaluation of in vitro neuronal platforms as surrogates #for in vivo whole brain systems

Submission open for coming issue@
 ","Fully validated systems hold promise for evaluating new drugs, characterizing toxicants, and aiding in the elucidation of disease mechanisms. Furthermore, neuronal cultures, in contrast to brain slices cultured on MEAs, are more readily adapted to human-relevant systems by utilizing either human primary or stem-cell derived neurons. As such, a direct comparison of dissociated neuronal cultures to whole brain provides important and necessary information to frame the relevance of in vitro data sets.","[5.0, 2.0, 2.0, 4.0, 2.0]",Biology,train,2.0,tweets,1025625636830883840
10.1038/nbt.2488,Biology_tweet_196,"Community-driven global reconstruction of human metabolism, new @username paper from our very own @username et al ",Recon 2 will facilitate many future biomedical studies and is freely available at http://humanmetabolism.org/.,"Community-driven global reconstruction of human metabolism, new @username paper from our very own @username et al ",Mapping metabolomic data and drug information onto Recon 2 demonstrates its potential for integrating and analyzing diverse data types. Recon 2 will facilitate many future biomedical studies and is freely available at http://humanmetabolism.org/. r e s o u r c e of interest to the community of researchers focused on the systems biology of metabolism of a target organism.,"[2.0, 4.0, 1.0, 1.0, 3.0]",Biology,train,2.2,tweets,309007917850435584
10.1038/s41558-018-0224-8,Biology_tweet_199,"Predicted end-of-the-century CO2 levels impair the olfactory system of marine fish, decreasing their chances of detecting food or predators. See the new article in @username Climate Change for more details! #CefasScience @username @username @username  ","Under elevated CO 2 the responses to l-alanine, l-arginine, l-glutamate, cyprinol sulfate, scymnol sulfate and alarm cue were up to 46% lower than those of controls (n = 6-11 fish per odorant per treatment, P = 0.027, P = 0.040, P = 0.028, P = 0.011, P = 0.012 and P = 0.018, respectively; Fig.","Predicted end-of-the-century CO2 levels impair the olfactory system of marine fish, decreasing their chances of detecting food or predators. See the new article in @username Climate Change for more details! #CefasScience @username @username @username  ","3) , but had no effect on the remainder (that is, elevated CO 2 did not increase the amplitude or sensitivity of the response to any of these odorants). Under elevated CO 2 the responses to l-alanine, l-arginine, l-glutamate, cyprinol sulfate, scymnol sulfate and alarm cue were up to 46% lower than those of controls (n = 6-11 fish per odorant per treatment, P = 0.027, P = 0.040, P = 0.028, P = 0.011, P = 0.012 and P = 0.018, respectively; Fig. The thresholds of detection for l-cysteine (P = 0.049), l-alanine (P = 0.029) and l-glutamate (P = 0.0047), and conspecific bile (P = 0.029) were two-to fivefold higher under elevated CO 2 (Fig.","[2.0, 4.0, 4.0, 3.0, 3.0]",Biology,train,3.2,tweets,1021411224062394370
10.1038/s41564-019-0426-5,Biology_tweet_2,"Wu, Ning, Zhang et al.: Global sampling &amp; #microbiome analysis of #wastewater treatment plants highlights high diversity with a 28 OTU core bacterial community linked to activated sludge performance:  ",Meta-analyses with global datasets associate the activated sludge microbiomes most closely to freshwater populations.,"Wu, Ning, Zhang et al.: Global sampling &amp; #microbiome analysis of #wastewater treatment plants highlights high diversity with a 28 OTU core bacterial community linked to activated sludge performance:  ","Despite this high diversity, activated sludge has a small, global core bacterial community (n = 28 operational taxonomic units) that is strongly linked to activated sludge performance. Meta-analyses with global datasets associate the activated sludge microbiomes most closely to freshwater populations. In contrast to macroorganism diversity, activated sludge bacterial communities show no latitudinal gradient.","[5.0, 3.0, 5.0, 2.0]",Biology,train,3.0,tweets,1127961946173652992
10.1038/s41467-018-07396-3,Biology_tweet_200,"#Graphene #Nanotech : New research reveals why graphene has not transformed electronics as promised, and shows how to double its performance to finally harness its extraordinary potential -  #MaterialsScience #QualityControl ","This leads to capacitance values much lower than the theoretical capacitance of graphene (550 F/g) 23 , with values of 409 F/g being the highest reported to date 24 .","#Graphene #Nanotech : New research reveals why graphene has not transformed electronics as promised, and shows how to double its performance to finally harness its extraordinary potential -  #MaterialsScience #QualityControl ","Moreover, this also indicates the possibility that the as-exfoliated graphene layers can each have different properties, again highlighting the importance of pure 2D materials. This leads to capacitance values much lower than the theoretical capacitance of graphene (550 F/g) 23 , with values of 409 F/g being the highest reported to date 24 . This calls for a broad effort to identify the types and extent of impurities present and the best way to deal with them to achieve the maximum potential of the broad family of 2D materials.","[2.0, 3.0, 1.0, 3.0]",Biology,train,2.25,tweets,1068092481848426496
10.1101/gr.171934.113,Biology_tweet_201,Ultrarapid cloud-compatible clinical sample NGS bioinformatics pipeline for pathogen identification ,"In particular, the speed and throughput of the pipeline make it highly convenient and cost-effective when run on a cloud server (Supplemental Table S1 ).",Ultrarapid cloud-compatible clinical sample NGS bioinformatics pipeline for pathogen identification ,"To our knowledge, SURPI is the only NGS pipeline for pathogen identification to be extensively tested across multiple clinical sample types representing a variety of infectious diseases (Figs. In particular, the speed and throughput of the pipeline make it highly convenient and cost-effective when run on a cloud server (Supplemental Table S1 ). SURPI analysis is also being incorporated as part of an ongoing effort to validate unbiased NGS assays for pathogen diagnosis in a CLIA (Clinical Laboratory Improvement Amendments)-certified laboratory.","[5.0, 2.0, 2.0]",Biology,train,2.0,tweets,474514458438795264
10.1016/j.cell.2018.04.034,Biology_tweet_202,An Immunogenic Class of #ProstateCancer | CDK12 Inactive | May benefit from #CheckPoint Blockade | Arul Chinnaiyan @username @username  ,CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ).,An Immunogenic Class of #ProstateCancer | CDK12 Inactive | May benefit from #CheckPoint Blockade | Arul Chinnaiyan @username @username  ,"However, our data, and the observations made previously in CDK12 mutant ovarian tumors , are inconsistent with that model. CDK12 mutant cases also lack mutational signatures of HRD ( Figure 3C ) and maintain the expression levels of BRCA1 and BRCA2 ( Figure S4J ). Overall, the genomic phenotypes of HR and CDK12 deficiency are clearly distinct.","[3.0, 1.0, 3.0, 1.0]",Biology,train,2.0,tweets,1007459186882605057
10.1126/sciadv.1500060,Biology_tweet_204,Fighting Crickets Rely on Nitric Oxide   #ScienceAdvances,"NO's effect is manifested in losers by prolonged avoidance behavior, characteristic for social defeat in numerous species.",Fighting Crickets Rely on Nitric Oxide   #ScienceAdvances,"Rather than suppressing aggressive motivation, NO increases susceptibility to aversive stimuli and with it the likelihood to flee. NO's effect is manifested in losers by prolonged avoidance behavior, characteristic for social defeat in numerous species. Intriguingly, fighting experience also induces, via NO, a brief susceptible period to aversive stimuli in winners just after victory.","[1.0, 4.0, 2.0, 3.0]",Biology,train,2.5,tweets,576442838524801024
10.1016/j.stemcr.2018.03.019,Biology_tweet_206,"Turning any cell of our body into a #StemCell? Yes we can! 

➡ How does reprogramming work? 
➡ Why does it make male and female cells behave differently? 

Find out at  or in @username ","Together, these results indicate that imprints are not only erased in XX iPSCs but also are not re-established upon global genome remethylation in XO iPSCs, which suggests that female iPSCs, regardless of the number of Xas, may have a similarly poor developmental potential as female ESCs .","Turning any cell of our body into a #StemCell? Yes we can! 

➡ How does reprogramming work? 
➡ Why does it make male and female cells behave differently? 

Find out at  or in @username ","Here, we found evidence of imprint erasure for the imprint control region of Zrsr1 in female XX and XO iPSCs (Table S2) . Together, these results indicate that imprints are not only erased in XX iPSCs but also are not re-established upon global genome remethylation in XO iPSCs, which suggests that female iPSCs, regardless of the number of Xas, may have a similarly poor developmental potential as female ESCs . Interestingly, we found that within several of these cis-regulatory regions, changes in average methylation levels were already apparent in both SSEA1 subpopulations, and more pronounced in XaXa iPSCs (Figures 3D-3G) .","[4.0, 1.0, 1.0, 2.0]",Biology,train,2.0,tweets,987313503169019904
10.14814/phy2.13617,Biology_tweet_208,Trouble sleeping?  Keep it dark in the evening.  ,"A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children.",Trouble sleeping?  Keep it dark in the evening.  ,"To our knowledge, this study is the first to quantify the melatonin suppression response to evening light exposure in healthy 3-to 5-year-old children. A combination of well-controlled procedures minimizing sources of error variance, a repeated-measures design, and large effect sizes led to several significant findings: (a) 1-h of bright light exposure before bedtime suppresses melatonin by~88%; (b) the effects of evening bright light exposure on melatonin levels persisted at least 50-min following termination of the light stimulus; and (c) melatonin levels remained attenuated and did not return to 50% of those observed in the dim light condition following the bright light exposure for the majority of the children. Findings from this study mark an important step in addressing a gap in understanding the melatonin suppression response across the lifespan.","[4.0, 2.0, 3.0, 4.0, 3.0]",Biology,train,3.2,tweets,970867976499970048
10.1210/en.2015-2036,Biology_tweet_209,"@username @username Studies have shown a relationship between low vitamin D and breast cancer.  
and there is evidence for the role of vitamin D in autoimmune diseases, as well as other conditions such as Type2 diabetes and CKD. ","We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) .","@username @username Studies have shown a relationship between low vitamin D and breast cancer.  
and there is evidence for the role of vitamin D in autoimmune diseases, as well as other conditions such as Type2 diabetes and CKD. ","This 'hit' was of particular interest because of the role of Id1 in BCa progression and most intriguing because calcitriol was found to induce, rather than repress, ID1 expression in a colon carcinoma cell line . We validated that Id1 expression was up-regulated in both tumors from vitamin D-deficient mice as well as in the VDR KD cells (Figure 3, A and B) . To test whether the regulation of Id1 by VDR is ligand dependent in BCa cells, we treated 168FARN cells with calcitriol and showed that this treatment represses the expression of Id1 ( Figure 3C ).","[4.0, 1.0, 3.0, 2.0, 3.0]",Biology,train,2.6,tweets,1035148272636182530
10.1111/gcb.13526,Biology_tweet_210, cool research showing reduced leaf number in soybean plants increases pod yield @username #photosynthesis,"Plants with optimal LAI are predicted to use 38% and 39% less carbon in constructing leaf tissue, than for the LAI observed in the field, under current and elevated [CO 2 ], respectively (Fig.", cool research showing reduced leaf number in soybean plants increases pod yield @username #photosynthesis,"However, as LAI is lowered below the optimum value, predicted losses in NPP become significant to the detriment of seed production. Plants with optimal LAI are predicted to use 38% and 39% less carbon in constructing leaf tissue, than for the LAI observed in the field, under current and elevated [CO 2 ], respectively (Fig. In fieldgrown soybean, it is observed to be largely maintained during seed fill through continued production of leaves, the period that is most critical for final yield .","[4.0, 1.0, 1.0, 2.0]",Biology,train,1.0,tweets,799660472228343816
10.1073/pnas.1405000111,Biology_tweet_212,Let's hit the ground running! How 'bout some science? Neotropical migration may actually have evolved from the north: ,"PlioPleistocene glaciations have clearly served to modify geographic ranges and migratory distances and routes and may have had an influence on more recent shifts of winter ranges out of North America in the Passerellidae (blue branches, Fig.",Let's hit the ground running! How 'bout some science? Neotropical migration may actually have evolved from the north: ,"As such, early shifts of winter ranges may not represent invasions of tropical habitats as much as tracking of tropical habitat to lower latitudes to escape harsh winter conditions while maintaining breeding at high latitudes ( . PlioPleistocene glaciations have clearly served to modify geographic ranges and migratory distances and routes and may have had an influence on more recent shifts of winter ranges out of North America in the Passerellidae (blue branches, Fig. 4) .","[1.0, 2.0, 3.0, 2.0]",Biology,train,2.0,tweets,498143012401057792
10.1007/s10336-017-1477-0,Biology_tweet_213,I spent a month in the Liberian rainforest searching for this bird. Now we know it was never a true species  ,That the Liberian Greenbul was heterozyogous at none of these positions strongly suggests that it was not an Icterine 9 Spotted Greenbul hybrid.,I spent a month in the Liberian rainforest searching for this bird. Now we know it was never a true species  ,"In contrast, there were 9 single-bp changes and a 2-bp indel between Icterine/Liberian Greenbul sequences and that of Spotted Greenbul. That the Liberian Greenbul was heterozyogous at none of these positions strongly suggests that it was not an Icterine 9 Spotted Greenbul hybrid. The current study has failed to find any significant genetic distance between Icterine and Liberian Greenbuls, whilst demonstrating large and diagnostic genetic distances between other species of greenbul in the genus Phyllastrephus.","[1.0, 5.0, 4.0, 5.0, 3.0]",Biology,train,4.0,tweets,894303427068444673
10.1038/s41467-018-04408-0,Biology_tweet_214,"Nice work in @username on a potential mechanism for the Sex Differences seen in autoimmunity:
Testosterone represses BAFF resulting in lower B cell numbers in men
","Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig.","Nice work in @username on a potential mechanism for the Sex Differences seen in autoimmunity:
Testosterone represses BAFF resulting in lower B cell numbers in men
","Indeed, Tnfsf13b (Baff) mRNA in the spleen was increased in G-ARKO mice (Fig. Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig. 3e) ; thus, testosterone downregulates splenic Baff mRNA in an AR-dependent manner.","[4.0, 4.0, 1.0, 1.0]",Biology,train,3.0,tweets,1004347698168856577
10.1126/science.aan2329,Biology_tweet_216,Exciting - probably flightless hatchlings and colonial breeding in Hamipterus! ,This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria.,Exciting - probably flightless hatchlings and colonial breeding in Hamipterus! ,"The geological context, including at least four levels with embryos and eggs, indicates that this deposit was formed by a rare combination of events, with storms acting on a nesting ground. This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria. The specimens can be attributed to Hamipterus tianshanensis, the sole species in this bonebed.","[2.0, 4.0, 1.0, 2.0, 3.0]",Biology,train,2.4,tweets,936317637088370688
10.1111/oik.03196,Biology_tweet_217,Will this new monarch scientific study change the direction of current continental conservation efforts? Have a... ,Monarch populations in Spring South significantly predict those in the Midwest.,Will this new monarch scientific study change the direction of current continental conservation efforts? Have a... ,"2 Spring South to Midwest Forward selection, Backward selection, and AIC all lead to Model 3, Midwest ⇠ Spring South with the donor region as the only significant predictor (p<0.05). Monarch populations in Spring South significantly predict those in the Midwest. There is no evidence for a temporal trend in this relationship.","[3.0, 1.0, 3.0]",Biology,train,2.333333333333333,tweets,720076984336850944
10.1016/j.stemcr.2018.02.011,Biology_tweet_218,"'we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus &amp; umbilical cord blood HSCs' 

",The NSG-W host strain's more thorough immuno-depletion and/or use of quickly processed neonatal patient thymic explants may also have influenced our results.,"'we describe the NeoThy humanized mouse model created using non-fetal human tissue sources, cryopreserved neonatal thymus &amp; umbilical cord blood HSCs' 

","In contrast, the robust circulating immune cells in the NeoThy are likely due to HSC co-injection coupled with human thymic education in vivo, as described below. The NSG-W host strain's more thorough immuno-depletion and/or use of quickly processed neonatal patient thymic explants may also have influenced our results. This contrasts with our ex vivo assay of T cell proliferation following TCR stimulation (Figures 3A and S2C) .","[2.0, 1.0, 4.0, 2.0]",Biology,train,2.25,tweets,985228715109048320
10.1098/rsbl.2017.0299,Biology_tweet_22,Frogs in the park:  global range expansion did not mean increased net-diversification    (HM library can obtain text) ,"Interestingly, and in striking contrast to expectations, the rapid global range expansion of true frogs was not associated with increased net diversification.",Frogs in the park:  global range expansion did not mean increased net-diversification    (HM library can obtain text) ,"We detected no shifts in extinction rates, nor signatures of mass extinction (electronic supplementary material, figure S3 ). Interestingly, and in striking contrast to expectations, the rapid global range expansion of true frogs was not associated with increased net diversification. On the contrary, diversification rates either decreased or remained unchanged, even as remarkable, circumglobal range expansion via dispersal and colonization of novel regions occurred.","[5.0, 5.0, 4.0, 5.0]",Biology,train,4.75,tweets,908267751126585344
10.1093/nar/gky1143,Biology_tweet_220,Need to relax? This is how DNA gyrase does it  @username,"Therefore, we suggest that the acute topological problem introduced by replication is primarily dealt with by gyrase enzymes performing processive catalysis to remove (+) supercoils ahead of replication, possibly at a higher rate than 1 supercoil/s, and we speculate that when gyrase fails to remove sufficient (+) supercoiling, replisome rotation is induced forming a substrate for topo IV behind the fork.",Need to relax? This is how DNA gyrase does it  @username,"In contrast, gyrase can remove (+) supercoils processively in vitro , consistent with our observations that its dwell time significantly increases close to the replisome. Therefore, we suggest that the acute topological problem introduced by replication is primarily dealt with by gyrase enzymes performing processive catalysis to remove (+) supercoils ahead of replication, possibly at a higher rate than 1 supercoil/s, and we speculate that when gyrase fails to remove sufficient (+) supercoiling, replisome rotation is induced forming a substrate for topo IV behind the fork. Our data suggest that local supercoiling may strongly influence gyrase off-rate, as we find with replication proximal gyrase remaining immobile for >8 s. Since the fork progresses at a rate of up to 1000 bp/s this would require initially binding ∼10 kb ahead of the fork to avoid collisions rather than directly ahead of it.","[4.0, 1.0, 1.0, 1.0]",Biology,train,1.0,tweets,1063535215283453953
10.1093/molbev/msw148,Biology_tweet_221,And is finally out! The evolution of visual pigments and ocular media in snakes ,"These changes are particularly common among dipsadine and colubrine ""higher"" snakes.",And is finally out! The evolution of visual pigments and ocular media in snakes ,"These changes are particularly common among dipsadine and colubrine ""higher"" snakes. All three opsin genes are inferred to be under purifying selection, though dN/dS varies with respect to some lineages, ecologies, and retinal anatomy. Positive selection was inferred at multiple sites in all three opsins, these being concentrated in transmembrane domains and thus likely to have a substantial effect on spectral tuning and other aspects of opsin function.","[3.0, 3.0, 2.0]",Biology,train,2.6666666666666665,tweets,765788480794419200
10.1073/pnas.1409328111,Biology_tweet_222,"Older mum's have children with more (heteroplasmic) mtDNA mutations. 

","Notably, we found a positive association between the number of heteroplasmies in a child and maternal age at fertilization, likely attributable to oocyte aging.","Older mum's have children with more (heteroplasmic) mtDNA mutations. 

","mutations per site per year, an order of magnitude higher than for nuclear DNA. Notably, we found a positive association between the number of heteroplasmies in a child and maternal age at fertilization, likely attributable to oocyte aging. Our results can be used to predict the transmission of disease-causing mtDNA variants and illuminate evolutionary dynamics of the mitochondrial genome.","[4.0, 5.0, 2.0, 4.0, 1.0]",Biology,train,4.0,tweets,521814952827310080
10.1073/pnas.1613337113,Biology_tweet_223,From the Graybiel lab at MIT: using expansion microscopy to reveal integrative units within dopaminergic circuitry. ,"With new mouse models and tissue expansion to allow nanoscale imaging, we demonstrate that striatonigral fibers originating in striosomes form bouquet-like arborizations innervating clusters of dopamine-containing neurons and their ventrally extending, tightly bundled dendrites.",From the Graybiel lab at MIT: using expansion microscopy to reveal integrative units within dopaminergic circuitry. ,"In the striosome lines P172-mCitrine and Sepw1-Cre NP67 with the Ai14 reporter (9), the proportion of striosomal fibers to With new mouse models and tissue expansion to allow nanoscale imaging, we demonstrate that striatonigral fibers originating in striosomes form bouquet-like arborizations innervating clusters of dopamine-containing neurons and their ventrally extending, tightly bundled dendrites. The stunning selectivity of striosomal output to the bouquets suggests that the bouquets could exert powerful and focused control over elements of the dopamine system in normal and abnormal states.","[1.0, 1.0, 4.0, 3.0]",Biology,train,2.0,tweets,777970964864831488
10.1111/gcb.13160,Biology_tweet_224,"New study shows most US #forests are threatened by #drought &amp; #climatechange:  
#UVM prof T. D'Amato is co-author.","Trees may be susceptible to drought-induced growth declines and mortality in two size/density situations, 1) at high-density conditions approaching the maximum size/density relationship, and 2) at low-density conditions conducive to the development of high levels of leaf area that promote canopy and root architecture that can put individual trees at risk.","New study shows most US #forests are threatened by #drought &amp; #climatechange:  
#UVM prof T. D'Amato is co-author.","Fire suppression can lead to a 'mesophication' as forest canopies close and may explain why oak regeneration appears to decline relative to that of red (Acer rubrum) and sugar (Acer saccharum) maples in recent decades . Trees may be susceptible to drought-induced growth declines and mortality in two size/density situations, 1) at high-density conditions approaching the maximum size/density relationship, and 2) at low-density conditions conducive to the development of high levels of leaf area that promote canopy and root architecture that can put individual trees at risk. Increased vulnerability of trees and forests to water stress and mortality risk from warmer droughts is a global phenomenon, well illustrated in the western U.SA.","[4.0, 4.0, 4.0, 3.0, 2.0]",Biology,train,3.4,tweets,701896242268344320
10.1093/icesjms/fsw166,Biology_tweet_227,Trade offs in marine protection: Higher #lobster numbers in a #MarineReserve reduced other crustacean species  ,"Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, and highlight the importance of investigating multispecies interactions, as the recovery of some species can have knock-on effects on others.",Trade offs in marine protection: Higher #lobster numbers in a #MarineReserve reduced other crustacean species  ,"Interestingly, catches of adult lobsters were inversely correlated with those of juvenile lobsters, brown crabs, and velvet crabs, which may be evidence of competitive displacement and/or predation. Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, and highlight the importance of investigating multispecies interactions, as the recovery of some species can have knock-on effects on others. If populations are to benefit from the protection afforded by MPAs, it is necessary that a number of individuals spend a substantial part of their lives within their boundaries .","[4.0, 3.0, 4.0]",Biology,train,3.6666666666666665,tweets,783207856120233984
10.1053/j.gastro.2013.10.059,Biology_tweet_228,Could liver SIRT1 play a key role in #obesity ? This paper certainly suggests so: ,Body composition analysis showed that SIRT1 LKO mice had increased fat mass without changed lean mass.,Could liver SIRT1 play a key role in #obesity ? This paper certainly suggests so: ,"SIRT1 LKO mice appeared to have increased adiposity with more visible fat, possibly due to increased adipocyte cell size. Body composition analysis showed that SIRT1 LKO mice had increased fat mass without changed lean mass. Daily food intake was similar between WT and SIRT1 LKO mice on a regular chow diet.","[3.0, 5.0, 5.0, 4.0, 5.0]",Biology,train,4.4,tweets,426105551081054208
10.1073/pnas.1519508113,Biology_tweet_229,Not just plants -here's a dromedary history analysis based on seq'g w/modern &amp; old samples  &amp; ,"Given the environmental context in which the wild dromedary would have evolved, it can be assumed that its native distribution and population size were generally quite restricted compared with the ancestral ranges of other livestock species before domestication.",Not just plants -here's a dromedary history analysis based on seq'g w/modern &amp; old samples  &amp; ,"S5 ) and increasingly disjointed before the global extinction of the wild populations less than two millennia after the appearance of the domestic form ) . Given the environmental context in which the wild dromedary would have evolved, it can be assumed that its native distribution and population size were generally quite restricted compared with the ancestral ranges of other livestock species before domestication. As suggested by the environmental context of the archaeological findings, the wild ancestors of C. dromedarius spent part of their lives foraging in coastal habitats including mangroves .","[4.0, 3.0, 1.0, 1.0]",Biology,train,2.0,tweets,729797197307355136
10.1098/rsos.180695,Biology_tweet_23,"Well, this is fascinating. Climate control allows us to create temp and moisture conditions we feel most comfortable in. So what climate do most Americans ""recreate"" in their homes? Western Kenya!    ",North American homes were most similar in climate to the outdoor conditions of west central Kenya (C ¼ 2.938).,"Well, this is fascinating. Climate control allows us to create temp and moisture conditions we feel most comfortable in. So what climate do most Americans ""recreate"" in their homes? Western Kenya!    ",The value distributions of the climate variables used in the climate dissimilarity index can be viewed in figure 1. North American homes were most similar in climate to the outdoor conditions of west central Kenya (C ¼ 2.938). The mean maximum temperature (average of all seasons) in the North American homes was 25.358C compared with 25.068C for the conditions outdoors in west central Kenya.,"[5.0, 5.0, 5.0, 3.0, 5.0]",Biology,train,4.6,tweets,1108466341353308160
10.1073/pnas.1511220112,Biology_tweet_233,'most parsimonious model for the evolution of hominin shoulder starts with an African ape-like ancestral state' #PNAS ,"Moreover, the likelihood of these alternative hypotheses can be directly tested using the better characterized later hominin fossil record.",'most parsimonious model for the evolution of hominin shoulder starts with an African ape-like ancestral state' #PNAS ,"This mix of character states raises the question of whether modern human morphology reflects evolution from a more derived African ape morphology or retention of primitive traits from an earlier ape ancestor. Moreover, the likelihood of these alternative hypotheses can be directly tested using the better characterized later hominin fossil record. Specifically, given alternative ancestral conditions, one can model the associated evolutionary trajectories and intermediate states connecting them to the descendant populations and test how well these predictions fit the available fossil evidence.","[2.0, 2.0, 2.0]",Biology,train,2.0,tweets,641316836009766912
10.1038/emi.2013.60,Biology_tweet_235,"SFV transmission suggests role for human activity,implications for macaque-human coexistence  #one health","The towns and villages that constituted research sites for our study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside synanthropic macaques.","SFV transmission suggests role for human activity,implications for macaque-human coexistence  #one health","Human/NHP interface in Asia differs from that in Africa The data presented here expand our knowledge of cross-species transmission of SFV in Asia. The towns and villages that constituted research sites for our study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside synanthropic macaques. [1] [2] [] In contrast to Africa, where bushmeat hunting and habitat degradation threaten to deplete NHP populations over the next decades, 4, 5 some synanthropic primate populations in Asia have actually thrived, and continue to be sustainable, in spite of the pressures presented by increasing human populations.","[1.0, 2.0, 1.0]",Biology,train,1.3333333333333333,tweets,377500254389559296
10.1038/s41467-017-01957-8,Biology_tweet_238,Today's shout-out to #womeninSTEM goes to Dr. Weini Huang @username  for her innovative study showing dynamical trade-offs from antagonistic coevolution that decrease intraspecific diversity    #microbial ecology #evolution #predatorprey #microbiology,This allowed us to describe the coevolutionary process without imposing a predefined number of prey or predator types.,Today's shout-out to #womeninSTEM goes to Dr. Weini Huang @username  for her innovative study showing dynamical trade-offs from antagonistic coevolution that decrease intraspecific diversity    #microbial ecology #evolution #predatorprey #microbiology,"Such a dynamical trade-off can potentially be important for the evolutionary and the ecological dynamics of species. This allowed us to describe the coevolutionary process without imposing a predefined number of prey or predator types. Consistent with our experiment, starting from naive populations, the trade-off curve changes from an initial shape of relatively cheap defense to be more costly with coevolution.","[1.0, 3.0, 3.0, 1.0, 1.0]",Biology,train,1.8,tweets,940964463787700225
10.1186/s13059-018-1616-9,Biology_tweet_24,interesting read on how gut bacteria are different between two countries which are both rural. this could be due to their culture that made for these differences. #BS3017 ,"From this observation, we infer that the gut bacteria are phylogenetically more distinct between groups defined by region (country) than by subsistence practice.",interesting read on how gut bacteria are different between two countries which are both rural. this could be due to their culture that made for these differences. #BS3017 ,"Comparing the magnitudes of difference between subsistence groups and geographic groups, we therefore find that the bacterial compositional difference between Tanzania and Botswana (a geographic grouping) is larger than between any of the African subsistence groups (both unweighted and weighted UniFrac F-statistics). From this observation, we infer that the gut bacteria are phylogenetically more distinct between groups defined by region (country) than by subsistence practice. The Hadza and Maasai had significantly larger unweighted UniFrac distances between sexes than expected by chance (PERMA-NOVA p value < 0.05) ( Fig.","[3.0, 5.0, 5.0, 4.0, 4.0]",Biology,train,4.2,tweets,1087658103225499651
10.1073/pnas.1420819112,Biology_tweet_240,metabolic theory and species identity predict reef nutrient cycling ,"Body nutrient content and trophic position explained little of the variation in E N , E P , or E NP , indicating limited applicability of basic predictors of EST.",metabolic theory and species identity predict reef nutrient cycling ,"In all cases, including taxonomy in models substantially improved model performance, highlighting the importance of species identity for this ecosystem function. Body nutrient content and trophic position explained little of the variation in E N , E P , or E NP , indicating limited applicability of basic predictors of EST. These results highlight the overriding importance of MTE for predicting nutrient flow through organisms, but emphasize that these relationships still fall short of explaining the unique effects certain species can have on ecological processes.","[3.0, 1.0, 1.0, 1.0]",Biology,train,1.5,tweets,590384086197252096
10.1038/s41467-019-08549-8,Biology_tweet_242,"""...when conditions deteriorate (negative disturbance) groups with high competency in both general and social intelligence are less likely to deplete resources and harvest more"" ","This does not occur where both g and ToM are high, perhaps signaling the emergence of a more well developed group intelligence.","""...when conditions deteriorate (negative disturbance) groups with high competency in both general and social intelligence are less likely to deplete resources and harvest more"" ","Groups with high g and low ToM harvest faster and push the resource system closer to its breaking point following a change in resource growth rate. This does not occur where both g and ToM are high, perhaps signaling the emergence of a more well developed group intelligence. Our results are consistent with the idea that both individual level intelligence and functioning as social groups are important for humans to solve socialecological challenges.","[1.0, 1.0, 1.0]",Biology,train,1.0,tweets,1098387481311891456
10.1016/j.celrep.2016.08.013,Biology_tweet_243,👉How #LymeDisease bacteria spread around the body  by @username ,"Therefore, counterintuitively, the small size of bacteria made them less sensitive to force and torque imposed by flow than leukocytes.",👉How #LymeDisease bacteria spread around the body  by @username ,"Average F s and T s experienced by bacteria were at least 10 times smaller than F s and T s experienced by rolling leukocytes at similar shear stresses , due to the relatively small B. burgdorferi radius. Therefore, counterintuitively, the small size of bacteria made them less sensitive to force and torque imposed by flow than leukocytes. Since most bacteria are as small or smaller than B. burgdorferi, this conclusion is likely to be true for other bacteria.","[2.0, 2.0, 2.0, 2.0]",Biology,train,2.0,tweets,769065624203059200
10.1126/scitranslmed.3010760,Biology_tweet_245,"Another day, another @username contribution to the fight --- tracking the mechanisms of transplant tolerance: ","The notion that some, but not all, deletion of donor-reactive clones in tolerant subjects may have reflected repertoire turnover was supported by analysis of third party-reactive T cells identified before transplant ( fig.","Another day, another @username contribution to the fight --- tracking the mechanisms of transplant tolerance: ","A significant and sustained reduction in the detection of donor-reactive compared to all CD8 + clones was observed in subjects 2 and 4, suggesting antigen-driven loss of donor-reactive CD8 clones (Fig. The notion that some, but not all, deletion of donor-reactive clones in tolerant subjects may have reflected repertoire turnover was supported by analysis of third party-reactive T cells identified before transplant ( fig. S8 ), some of which showed posttransplant reductions.","[3.0, 4.0, 2.0, 1.0]",Biology,train,2.5,tweets,561198663460847618
10.1093/beheco/aru103,Biology_tweet_246,Artificial night lighting affects dawn and dusk singing in European song birds. Some robins even sing all night! ,"We cannot exclude that early or late disturbance by humans (e.g., pedestrians, joggers) might have woken up the birds earlier during the weekend or drove the blue tits to be active later at dusk.",Artificial night lighting affects dawn and dusk singing in European song birds. Some robins even sing all night! ,"High noise levels during the week may reduce the efficiency of communication, and males may compensate by singing more and somewhat earlier during the weekends. We cannot exclude that early or late disturbance by humans (e.g., pedestrians, joggers) might have woken up the birds earlier during the weekend or drove the blue tits to be active later at dusk. The absence of a clear noise effect seems to contradict previous studies that documented effects of noise pollution on the timing of singing.","[2.0, 1.0, 2.0, 3.0]",Biology,train,2.0,tweets,510499396622905344
10.1126/science.aat4082,Biology_tweet_248,"Hungry plants invite hungry bugs: competition for iron nutrition
  
   ",We identify an iron transporter that allows the corn rootworm to benefit from complexes between iron and benzoxazinoids.,"Hungry plants invite hungry bugs: competition for iron nutrition
  
   ","We show that the root-feeding larvae use complexes between iron and benzoxazinoid secondary metabolites to identify maize as a host, to forage within the maize root system, and to increase their growth. We identify an iron transporter that allows the corn rootworm to benefit from complexes between iron and benzoxazinoids. In addition, root-feeding WCR larvae prefer benzoxazinoidproducing maize plants and require benzoxazinoids to identify crown roots as the preferred feeding site (6) .","[1.0, 3.0, 4.0]",Biology,train,2.0,tweets,1030151190787645440
10.1038/s41467-018-04334-1,Biology_tweet_249,Single cell RNAseq from 1053 primary human breast epithelial cells identifies several previously unrealized luminal and basal epithelial subpopulations  and a ZEB1-positive basal bi-potent stem/progenitor cells ,"Understanding the origins of breast cancer in its earliest phases has the potential to advance methods of cancer early detection, and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease.",Single cell RNAseq from 1053 primary human breast epithelial cells identifies several previously unrealized luminal and basal epithelial subpopulations  and a ZEB1-positive basal bi-potent stem/progenitor cells ,"Instead, the outcome of our Monocle analysis is in favor of the existence of the bi-potent stem/progenitor model as it clearly identified one continuous trajectory indicative of a common source for both basal and luminal cell differentiation. Understanding the origins of breast cancer in its earliest phases has the potential to advance methods of cancer early detection, and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease. The luminal epithelial cell type L2 showed the clearest correlation with both Luminal A and B subtypes from the Metabric dataset , which is in line with previously reported similarities between a FACS-enriched population of mature luminal cells and the luminal-like breast cancer subtypes .","[4.0, 2.0, 3.0, 3.0, 3.0]",Biology,train,3.0,tweets,999245589484396544
10.1016/j.neuron.2017.06.028,Biology_tweet_250,The PNN protein Brevican modulates cellular and synaptic plasticity in PV+ cells  ,"Hence, the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning, and memory associated with a repertoire of diseases.",The PNN protein Brevican modulates cellular and synaptic plasticity in PV+ cells  ,"By simultaneously regulating the excitatory inputs and firing properties of PV+ cells, a perineuronal net protein drives PV+ interneuron wiring as well as network adaptation to experience. Hence, the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning, and memory associated with a repertoire of diseases. Consistently, pharmacological degradation of CSPGs in the adult reactivates cortical plasticity and enhances learning .","[4.0, 2.0, 1.0, 1.0]",Biology,train,2.0,tweets,886969444064481280
10.1016/j.cell.2015.07.058,Biology_tweet_253,Getting ready to read this fresh article  sounds exciting! @username #virus #DNArepair,MRN senses and binds to early replicating virus genomes where it recruits ATM and activates a localized signaling response that selectively prevents virus genome replication.,Getting ready to read this fresh article  sounds exciting! @username #virus #DNArepair,"The localized MRN-ATM response provides an elegant mechanism to selectively neutralize viral replication without jeopardizing cellular replication and viability. MRN senses and binds to early replicating virus genomes where it recruits ATM and activates a localized signaling response that selectively prevents virus genome replication. In WT Ad5-infected cells, E1B-55K and E4-ORF3 inactivate MRN and enable virus genome replication.","[1.0, 2.0, 1.0]",Biology,train,1.3333333333333333,tweets,636979929016631296
10.1038/s41467-018-04151-6,Biology_tweet_254,There are a surprisingly limited number of ways a network could be constructed to perform perfect adaptation.  #cellcommunication #nature #networks,This has important implications for the interconnections of the module with other parts of the RPA-capable network.,There are a surprisingly limited number of ways a network could be constructed to perform perfect adaptation.  #cellcommunication #nature #networks,"The single independent regulator of each opposer node, and its dependents (all marked in green) do exhibit the RPA property. This has important implications for the interconnections of the module with other parts of the RPA-capable network. The symbol S N indicates that any motif or sub-network may be fully embedded at the indicated position.","[3.0, 2.0, 4.0, 2.0]",Biology,train,2.75,tweets,991934061500424192
10.1016/j.cell.2014.12.038,Biology_tweet_256,Copy-number variations in #microbiome of #human gut  From Borenstein lab @username ,"Notably though, we did not detect significantly more variation in clusters for which more reference genomes were available.",Copy-number variations in #microbiome of #human gut  From Borenstein lab @username ,"First, our analysis is limited to the detection of variation in gut species for which at least one fully sequenced genome is available, and future studies may benefit from additional genomes. Notably though, we did not detect significantly more variation in clusters for which more reference genomes were available. In addition, our pipeline was designed to detect gene losses or amplifications but cannot identify gain of genes that are not present in any of the reference genomes included in the genome cluster.","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,tweets,560916396356300801
10.1016/j.cell.2015.02.011,Biology_tweet_257,New potential treatment for JAK2 based MPNs arising from selective re-orientation of defected EPO receptors  #Science,"However, dimer reorientation could be achieved by many different types of engineered scaffolds.",New potential treatment for JAK2 based MPNs arising from selective re-orientation of defected EPO receptors  #Science,"This strategy is applicable to diseases mediated by mutated, constitutively active receptors and could offer the advantage of specificity and reduced toxicity versus broadly neutralizing kinase inhibitors. However, dimer reorientation could be achieved by many different types of engineered scaffolds. A range of altered dimerization geometries could be screened with different dimerizing scaffolds for those that induced a particular signaling profile or functional property.","[1.0, 4.0, 1.0, 1.0]",Biology,train,1.0,tweets,577605770856022016
10.1086/693564,Biology_tweet_258,"Updated estimation of the the number of species suggests that the Creator has an inordinate fondness for bacteria.
 ","We readily acknowledge that the free-living biodiversity of soils may also be extensive, and its inclusion might change our estimates somewhat.","Updated estimation of the the number of species suggests that the Creator has an inordinate fondness for bacteria.
 ","Second, in some groups we did not include estimates of their free-living diversity, especially in soils (e.g., mites, nematodes, protists, and bacteria). We readily acknowledge that the free-living biodiversity of soils may also be extensive, and its inclusion might change our estimates somewhat. However, additions of a few million species, as for soil fungi , would have little impact on our main results (Table 1) .","[2.0, 1.0, 2.0]",Biology,train,1.6666666666666667,tweets,900994170445287425
10.1038/s41588-019-0405-z,Biology_tweet_259,And here is the next #peanut genome paper  in @username from #IPGI @username showing single origin for cultivated peanut &amp; its wild counterpart A. monticola. We together with @username contributed #HiC assembly to this work. @username @username ,"Within genes, the B subgenome was enriched relative to the A subgenome for DNA sequences that corresponded to small RNAs ( Supplementary Fig.",And here is the next #peanut genome paper  in @username from #IPGI @username showing single origin for cultivated peanut &amp; its wild counterpart A. monticola. We together with @username contributed #HiC assembly to this work. @username @username ,"However, greater densities of DNA sequences that corresponded to uniquely mapping small RNAs were found in gene-rich chromosomal regions ( Supplementary  Fig. Within genes, the B subgenome was enriched relative to the A subgenome for DNA sequences that corresponded to small RNAs ( Supplementary Fig. As has been reported in other recent polyploids 27 , overall, the number of homeologous gene pairs with expression biased towards the A subgenome was not significantly different from the number biased towards the B subgenome (P = 0.2, two-sided binomial test; n = 3,648 and 3,759 for A and B, respectively).","[1.0, 2.0, 2.0, 1.0, 1.0]",Biology,train,1.4,tweets,1123612112490598400
10.1073/pnas.1219361110,Biology_tweet_26,Larger penis size and greater height have almost equivalent effects on male attractiveness. ,Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans.,Larger penis size and greater height have almost equivalent effects on male attractiveness. ,"Surprisingly, larger penis size and greater height had almost equivalent positive effects on male attractiveness. Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans. More broadly, our results show that precopulatory sexual selection can play a role in the evolution of genital traits.","[4.0, 2.0, 3.0, 4.0, 2.0]",Biology,train,3.0,tweets,321347885633531904
10.1038/s41467-017-00962-1,Biology_tweet_260,Our paper with Hopkins providing genomic evidence that many ovarian cancers start in the fallopian tube. @username ,"As expected, we identified sequence changes in the TP53 tumor suppressor gene, a wellknown driver gene in HGSOC, in all cases.",Our paper with Hopkins providing genomic evidence that many ovarian cancers start in the fallopian tube. @username ,"Whole-exome sequence analyses of the tumor samples from each patient identified somatic mutations that were present in all neoplastic samples analyzed as well as specific changes that were present in individual or subsets of tumors (Fig. As expected, we identified sequence changes in the TP53 tumor suppressor gene, a wellknown driver gene in HGSOC, in all cases. The TP53 alterations were identical in all samples analyzed for each patient including in the p53 signatures, the STIC lesions, and other carcinomas.","[2.0, 2.0, 1.0]",Biology,train,1.6666666666666667,tweets,922415510591098881
10.1002/ajp.22168,Biology_tweet_261,Just Published: Developing a questionnaire to measure chimpanzee personality via top-down/bottom-up design ,"There was a positive correlation between play behavior and Openness, as has been found previously for the trait ""curious"" .",Just Published: Developing a questionnaire to measure chimpanzee personality via top-down/bottom-up design ,"Openness, which includes traits such as intelligent, inquisitive, human oriented, and inventive, had mixed predictive validity. There was a positive correlation between play behavior and Openness, as has been found previously for the trait ""curious"" . However, with Openness, there was also a positive correlation with submissive behavior and negative correlations with proximity and social grooming behaviors, none of which had been seen in previous studies .","[1.0, 2.0, 1.0]",Biology,train,1.3333333333333333,tweets,392365762444144640
10.1038/s41467-017-00525-4,Biology_tweet_262, Researchers Slow Aging and Extend Lifespan of Fruit Flies #science,"Critically, short-term, midlife induction of Drp1 improves proteostasis in aged animals.", Researchers Slow Aging and Extend Lifespan of Fruit Flies #science,"Taken together, our findings reveal that the midlife shift toward more elongated mitochondria, in flight muscle, contributes to age-onset proteotoxicity. Critically, short-term, midlife induction of Drp1 improves proteostasis in aged animals. RU486 had no significant impact on the accumulation of protein aggregates in control flies ( Supplementary Fig.","[3.0, 4.0, 1.0, 4.0]",Biology,train,3.0,tweets,905420468202721280
10.3389/fphar.2013.00071,Biology_tweet_263,Sweet...The effects of cocoa on the immune system ,The primary function of Th17 cells appears to be the clearance of pathogens that are not adequately handled by Th1 or Th2 cells and they are potent inducers of tissue inflammation ( .,Sweet...The effects of cocoa on the immune system ,"After naïve Th cell activation and proliferation, effector Th lymphocytes appear. The primary function of Th17 cells appears to be the clearance of pathogens that are not adequately handled by Th1 or Th2 cells and they are potent inducers of tissue inflammation ( . No changes in the secretion of this cytokine were observed in splenocytes , although others found increased values , and in vitro studies demonstrated a suppression of IFN-γ production by PHA-stimulated PBMC (Jenny et al., 2009) .","[2.0, 2.0, 2.0, 1.0, 2.0]",Biology,train,1.8,tweets,345289329435889664
10.1038/ncomms4632,Biology_tweet_264,"Nanotech rising..

",The demonstration of nanomotors for biochemical release as shown above is still in a non-bioenvironment.,"Nanotech rising..

","Such molecule release mechanism is applicable not only to Raman-sensitive molecules but also to any biochemicals of interests, such as drugs, cytokine, DNA, antigens and antibodies. The demonstration of nanomotors for biochemical release as shown above is still in a non-bioenvironment. More experiments are necessary to study the applications and limitations of nanomotors in a biosetting.","[2.0, 1.0, 2.0]",Biology,train,1.6666666666666667,tweets,469374649865093120
10.1016/j.immuni.2019.05.007,Biology_tweet_265,Great paper by Lindesmith et al mapping antibody responses after norovirus immunization. Amazing how little we know about a virus that kills so many ⁦@username⁩ #norovirus  ,"A1431 had very extensive breadth and potency not only towards all historical strains available but also towards prospective GII.4 strains that appeared after the vaccine trial, including GII.4 2012 and 2015, neither of which had circulated in the general population at the time of sample collection ( Figure 2B ).",Great paper by Lindesmith et al mapping antibody responses after norovirus immunization. Amazing how little we know about a virus that kills so many ⁦@username⁩ #norovirus  ,"Finally, the third class of serum antibodies had a single member, A1431, which had strong blockade activity to all known historical GII.4 strains from 1987 onwards. A1431 had very extensive breadth and potency not only towards all historical strains available but also towards prospective GII.4 strains that appeared after the vaccine trial, including GII.4 2012 and 2015, neither of which had circulated in the general population at the time of sample collection ( Figure 2B ). Furthermore, A1431 potently neutralized GII.P16-GII.4 Sydney virus, a GII.4 strain that emerged 5 years post sample collection, in a human intestinal enteroid culture system ) (IC 50 5.5 ng/mL), supporting the correlation between blockade of ligand-binding potency and antibody-mediated neutralization ( Figures 2C and S1 ) (Alvarado et al., 2018; ) .","[1.0, 4.0, 2.0, 1.0]",Biology,train,2.0,tweets,1141051718144335872
10.1073/pnas.1301764110,Biology_tweet_266,Tfr1 as an HCV entry factor (PNAS) (sub)  #mondaymicro,"Although not a robust assay, analogous to previous reports, we observed a threefold increase in HCVcc binding to CHO cells expressing human SRBI than to parental CHO cells, and this binding was more pronounced than that detected on CHO cells expressing CD81.",Tfr1 as an HCV entry factor (PNAS) (sub)  #mondaymicro,"HCV Particle Binds to TfR1. Although not a robust assay, analogous to previous reports, we observed a threefold increase in HCVcc binding to CHO cells expressing human SRBI than to parental CHO cells, and this binding was more pronounced than that detected on CHO cells expressing CD81. Likewise, CHO cells expressing TfR1 exhibited greater than a threefold increase in HCVcc binding over background (Fig.","[3.0, 2.0, 5.0]",Biology,train,2.0,tweets,344208265288220673
10.1126/scitranslmed.3008325,Biology_tweet_267,[Research Articles] Closed-loop neuromodulation of spinal sensorimotor circuits controls… ,"Animals with complete spinal cord injury performed more than 1000 successive steps without failure, and were able to climb staircases of various heights and lengths with precision and fluidity.",[Research Articles] Closed-loop neuromodulation of spinal sensorimotor circuits controls… ,"These developments allowed us to conceive a neuroprosthetic system that controlled a broad range of foot trajectories during continuous locomotion in paralyzed rats. Animals with complete spinal cord injury performed more than 1000 successive steps without failure, and were able to climb staircases of various heights and lengths with precision and fluidity. Beyond therapeutic potential, these findings provide a conceptual and technical framework to personalize neuromodulation treatments for other neurological disorders.","[1.0, 4.0, 2.0, 2.0, 2.0]",Biology,train,2.2,tweets,514850371085152256
10.1111/j.1752-8062.2011.00370.x,Biology_tweet_269,"I promised for an animal model that develop hypercholesterolemia induced by state of fat adaptation, here's this animal model, the animal was the hibernating Brown Bears.
@username @username @username @username ",This species might serve as a reverse translational model for atherosclerosis resistance.,"I promised for an animal model that develop hypercholesterolemia induced by state of fat adaptation, here's this animal model, the animal was the hibernating Brown Bears.
@username @username @username @username ","Brown bears tolerate elevated cholesterol levels, obesity, physical inactivity, and circulatory slow fl ow during hibernation without signs of atherosclerosis. This species might serve as a reverse translational model for atherosclerosis resistance. Th e experimental design of recaptuing provides controls for both internal and external eff ects (body and external temperature, feeding status, metabolic rate) in accordance with recommendations by Carey et al.","[1.0, 1.0, 1.0, 2.0]",Biology,train,1.25,tweets,1008749330373791744
10.1038/s41467-018-06236-8,Biology_tweet_27,Roundworm study documents paternal transmission of epigenetic memory via sperm About 10 percent of histone packaging is retained in both human and mouse sperm.   #epigenetics #hereditary #biology #genetics @username @username ,The finding that abnormal retention of an epigenetic memory of spermatogenesis compromises germline health 36 suggests that sperm epigenetic marking must be reset each generation.,Roundworm study documents paternal transmission of epigenetic memory via sperm About 10 percent of histone packaging is retained in both human and mouse sperm.   #epigenetics #hereditary #biology #genetics @username @username ,"We speculate that multivalent marking in C. elegans sperm serves a different function than in zebrafish and mammalian sperm, namely to enable an epigenetic memory of spermatogenesis to be reset. The finding that abnormal retention of an epigenetic memory of spermatogenesis compromises germline health 36 suggests that sperm epigenetic marking must be reset each generation. Multivalent marking of chromatin domains may serve diverse functions depending on biological context, developmental tissue and stage, and organism.","[3.0, 4.0, 4.0, 2.0, 3.0]",Biology,train,3.2,tweets,1052537409467023360
10.1038/s41598-019-42251-5,Biology_tweet_270,"Scientists have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells. Their findings could prove to be a breakthrough in not only treating tumors, but ensuring cancer doesn't return years later.  ","E-Cadherin expressing NCI-H522 cells exhibited an epithelial growth pattern in vitro, unlike the parental cells, which showed less cell-cell contact (Fig.","Scientists have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells. Their findings could prove to be a breakthrough in not only treating tumors, but ensuring cancer doesn't return years later.  ","Sensitivity to paclitaxel, etoposide, imatinib and gefitinib did not correlate with vimentin expression (Fig. E-Cadherin expressing NCI-H522 cells exhibited an epithelial growth pattern in vitro, unlike the parental cells, which showed less cell-cell contact (Fig. Exposure of reconstituted cells to either U0126 or 4 did not affect expression of exogenous E-cadherin (Fig.","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,tweets,1148946853062299648
10.1016/j.cell.2016.09.056,Biology_tweet_271,"See!  I told you they were important. And congratulations to Steve Blacklow for igniting the tetraspanin field.
",Our molecular dynamics simulations suggest that CD81 may exist in both closed and open conformations and that the equilibrium between closed and open conformations may be shifted toward the closed state when cholesterol is bound.,"See!  I told you they were important. And congratulations to Steve Blacklow for igniting the tetraspanin field.
","Our results reveal that CD81 binds cholesterol and that E219 is an important residue in the binding pocket, offering a potential mechanism for how tetraspanins might detect cholesterol or other membrane lipids (whereas CD81 and tspan10 both possess a polar residue in this position, most other tetraspanins have a polar residue one helical turn earlier, with other cholesterol-interacting residues highly conserved throughout evolution). Our molecular dynamics simulations suggest that CD81 may exist in both closed and open conformations and that the equilibrium between closed and open conformations may be shifted toward the closed state when cholesterol is bound. Modulation of tetraspanin conformation in response to differences in cholesterol concentration could explain how tetraspanins regulate the subcellular localization of their partner proteins D117   K116   D117   K201   D196   TM3  TM3  TM4  TM4   EC2  EC2   EC2   EC2   TM1   TM2   TM3   TM4   F58 F126 6 6 6 6 6 6 6 6 6 6 6 6 6 E EC2","[1.0, 1.0, 1.0]",Biology,train,1.0,tweets,791998144724729856
10.1038/nature09273,Biology_tweet_272,RT @username More common rainforest trees are less susceptible to soil-based pathogens. Neat! #Biodiversity  …,Both experiments provide strong evidence for negative plant-soil feedback mediated by soil biota.,RT @username More common rainforest trees are less susceptible to soil-based pathogens. Neat! #Biodiversity  …,"Such patterns of density and distance dependence are expected to emerge if the process of enemy-mediated negative feedback is operating in the plant community. Both experiments provide strong evidence for negative plant-soil feedback mediated by soil biota. In contrast, above-ground enemies (mammals, foliar herbivores and foliar pathogens) contributed little to negative feedback observed in the field.","[4.0, 5.0, 2.0, 1.0, 3.0]",Biology,train,2.0,tweets,515180354681192449
10.1038/srep01456,Biology_tweet_273,I could not resist this. ,"Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection.",I could not resist this. ,"Moreover, among 21 field bed bug populations tested, 100% of populations were associated with at least two molecular mechanisms (not including LA-1 the reference population), implying the prevalent involvement of multiple mechanisms of pyrethroid resistance in the field bed bug populations. Bed bugs injected with dsRNA of malE or target genes suffered ,10% mortality within 6 days after injection. The target genes tested were successfully suppressed by RNAi (Fig.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,tweets,420129662275039232
10.1073/pnas.1507055113,Biology_tweet_274,The real Paleo diet: what did our ancestors eat for dinner?  Congrats to Clay Magill on his new paper in PNAS!  ,"In the farthest southeastern (FLK S ) trenches, high C/V values and high δ 13 C values for C lignin phenols (Fig.",The real Paleo diet: what did our ancestors eat for dinner?  Congrats to Clay Magill on his new paper in PNAS!  ,"3 and 4A ) collectively indicate dense woody cover (Fig. In the farthest southeastern (FLK S ) trenches, high C/V values and high δ 13 C values for C lignin phenols (Fig. Biomarkers define a heterogeneous landscape at Olduvai and suggest an influence of local resources on hominin diets and behavior.","[1.0, 1.0, 1.0]",Biology,train,1.0,tweets,701908541242798080
10.1016/j.cub.2007.01.061,Biology_tweet_275,"#NYK That rats, like dolphins and humans, are thought to have metacognition, the awareness of your ability to think. ",The other aperture (referred to as the decline-the-test response) led to the omission of the duration test.,"#NYK That rats, like dolphins and humans, are thought to have metacognition, the awareness of your ability to think. ","By contrast, more widely spaced intervals (e.g., 2 and 8 s) are easiest to classify. The other aperture (referred to as the decline-the-test response) led to the omission of the duration test. In the test phase, a correct lever press with respect to the duration discrimination produced a large reward of six pellets; an incorrect lever press produced no reward.","[1.0, 1.0, 1.0, 2.0]",Biology,train,1.25,tweets,876311778724020224
10.1126/sciadv.1601660,Biology_tweet_276,"A common problem in flexography is dot gain during impression, but some amazing advances are being made to improve resolution with nanoporous microstructures. @username #gc3400
","When this stamp is used to print, the excess ink spreads upon contact, resulting in greater width and corner roundness of the printed features compared to the stamp and an overall loss of pattern fidelity ( fig.","A common problem in flexography is dot gain during impression, but some amazing advances are being made to improve resolution with nanoporous microstructures. @username #gc3400
","However, we find that a slight amount of excess ink is present on the stamp surface. When this stamp is used to print, the excess ink spreads upon contact, resulting in greater width and corner roundness of the printed features compared to the stamp and an overall loss of pattern fidelity ( fig. When the CNT stamp is then used for printing, uniform ink transfer is achieved by relying on the formation of nanoscale contact points across the surface of each microscale stamp feature, therefore replicating the shapes of the stamp features with high accuracy.","[2.0, 1.0, 1.0, 2.0, 2.0]",Biology,train,1.6,tweets,1044630850992779275
10.1016/j.mito.2018.08.001,Biology_tweet_277,@username @username Naviaux's paper I mentioned above: ,Over 100 chronic illnesses can be classified according to the stage of the CDR that is blocked (Table 1) .,@username @username Naviaux's paper I mentioned above: ,"The savings in a single year would be more than the annual budgets of the National Institutes of Health (NIH; $37 billion), Environmental Protection Agency (EPA; $8.7 billion), Food and Drug Administration (FDA; $5.1 billion), and the US Department of Agriculture (USDA; $151 billion) combined. Over 100 chronic illnesses can be classified according to the stage of the CDR that is blocked (Table 1) . Metabolic addiction to the chemistry produced by different stages of the CDR can occur.","[2.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.2,tweets,1031941304387821570
10.1126/sciadv.1700581,Biology_tweet_278,Flooding dominates news but new research shows Jordan faces new 25 droughts per 30 year cycle compared to 8 now ,These impacts are especially worth considering for the 278 transboundary waterways (37) associated with shared watersheds occupying nearly half of the world's land .,Flooding dominates news but new research shows Jordan faces new 25 droughts per 30 year cycle compared to 8 now ,Water security assessments spanning future decades would greatly benefit from reflecting on the joint impacts of multiple drought types and humaninduced land-use change. These impacts are especially worth considering for the 278 transboundary waterways (37) associated with shared watersheds occupying nearly half of the world's land . Future water security concerns are critical in arid countries reliant on transboundary freshwater resources and where the combined effects of future droughts and humaninduced land-use changes are likely to continue.,"[3.0, 3.0, 1.0, 1.0, 1.0]",Biology,train,1.8,tweets,903511598232477696
10.1038/s41467-018-04251-3,Biology_tweet_279,Further reading: ,The EP degeneracy featured by zero scattering eigenvalue splitting is designed at 632.8 nm by optimizing the respective thicknesses of Au and PMMA layers.,Further reading: ,Spatially resolved thermal mapping. The EP degeneracy featured by zero scattering eigenvalue splitting is designed at 632.8 nm by optimizing the respective thicknesses of Au and PMMA layers. The abrupt EP phase transition can be fully characterized by the quasi-linear response of forward reflection with almost negligible differences.,"[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,tweets,991765852956524544
10.1073/pnas.1504869112,Biology_tweet_28,Lianas: reducing carbon gain and storage in tropical forests  @username @username @username,These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .,Lianas: reducing carbon gain and storage in tropical forests  @username @username @username,"The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( . Nonetheless, these initial studies indicate that increasing liana abundance may alter the carbon balance and cycle of tropical forests by reducing forestlevel carbon storage and sequestration.","[4.0, 4.0, 4.0, 3.0, 2.0]",Biology,train,3.4,tweets,654223530092052480
10.1016/j.neuron.2018.12.026,Biology_tweet_280,"""These findings suggest E-I ratio changes are compensatory in autism."" We've got a game-changer here...... ","Averaging across WT cells revealed a smooth contour of G ex /G in scaling combinations that predict no change in PSP peak (PSP diff = 0), which we term the ''PSP stability contour'' ( Figure 3D , thick contour).","""These findings suggest E-I ratio changes are compensatory in autism."" We've got a game-changer here...... ","Instead, equal weakening of G ex and G in reduces PSP peak, and further weakening of G in restores it (example cell, Figure 3C ). Averaging across WT cells revealed a smooth contour of G ex /G in scaling combinations that predict no change in PSP peak (PSP diff = 0), which we term the ''PSP stability contour'' ( Figure 3D , thick contour). This contour is (D) Contour plot of mean predicted change in overall PSP peak for different combinations of Gex and Gin scaling, for all Cntnap2 +/+ cells.","[3.0, 3.0, 1.0, 1.0, 1.0]",Biology,train,1.8,tweets,1087909946073612288
10.4049/jimmunol.1400569,Biology_tweet_281,A new treatment for #gumdisease?  (£),These data show that C3 is required for maximal inflammation and bone loss in P. gingivalis-induced periodontitis in mice.,A new treatment for #gumdisease?  (£),"1B and 1C, respectively) . These data show that C3 is required for maximal inflammation and bone loss in P. gingivalis-induced periodontitis in mice. Consistent with its ability to activate C5aR independently of the canonical activation of the complement cascade, P. gingivalis retained its capacity to colonize the periodontium of C3 2/2 mice and significantly increased total microbiota counts (comparable with its effects in WT mice), as determined 7 d postinoculation (p , 0.01; Fig.","[3.0, 3.0, 3.0]",Biology,train,3.0,tweets,490817207090548736
10.1016/j.cmet.2017.08.006,Biology_tweet_282,Blankets and  L-Carnitine For Grandparents To Stay Warm  #fuelingtactics,"HNF4α binding peaks were observed in proximity to promoters of PPARα, Cpt1b, Octn2, and CrAT ( Figure 5F ).",Blankets and  L-Carnitine For Grandparents To Stay Warm  #fuelingtactics,"Although Cpt1 and Cpt2 regulation by HNF4α is well established, we also observed reduction in Octn2 and CrAT expression in the livers of hepatocyte-selective HNF4α null mice . HNF4α binding peaks were observed in proximity to promoters of PPARα, Cpt1b, Octn2, and CrAT ( Figure 5F ). Together these findings suggest that hepatic HNF4α is a major regulator of the cold adaptive response in the liver.","[1.0, 1.0, 2.0, 1.0]",Biology,train,1.25,tweets,905439179475169280
10.1007/s00244-015-0196-x,Biology_tweet_283,This is a really interesting paper demonstrating exposure of bats to pharmaceuticals and other emerging contaminants ,Infusion of prostaglandin PGE 2 into the brains of hibernating golden-mantled ground squirrels (Spermophilus lateralis) caused periodic arousals along with increased body temperature .,This is a really interesting paper demonstrating exposure of bats to pharmaceuticals and other emerging contaminants ,"In Asian chipmunks (Tamias asiaticus), prostaglandin PGD 2 increased in the brain to a maximum in February and declined by April suggesting a correlation between PGD 2 and hibernation . Infusion of prostaglandin PGE 2 into the brains of hibernating golden-mantled ground squirrels (Spermophilus lateralis) caused periodic arousals along with increased body temperature . These studies suggest that prostaglandin levels are related to hibernation in at least these three mammalian species.","[2.0, 1.0, 1.0, 1.0]",Biology,train,1.25,tweets,629322328791453696
10.1073/pnas.1702798114,Biology_tweet_284,Our latest paper on using antibiofilm glycoside hydrolases (PelA and Sph3) with animal model just out in @username  ,Biofilm disruption was associated with a marked reduction in hyphae-associated GAG as detected by lectin staining (Fig.,Our latest paper on using antibiofilm glycoside hydrolases (PelA and Sph3) with animal model just out in @username  ,"Treatment with Sph3 h for 1 h disrupted established A. fumigatus biofilms with an effective concentration for 50% activity (EC 50 ) of 0.45 ± 1.31 nM (Fig. Biofilm disruption was associated with a marked reduction in hyphae-associated GAG as detected by lectin staining (Fig. A catalytic variant Sph3 h D166A, which does not mediate GAG hydrolysis , displayed a greater than 500-fold reduction in antibiofilm activity (Fig.","[3.0, 1.0, 2.0, 2.0]",Biology,train,2.0,tweets,877342873104117760
10.1038/s41467-018-04906-1,Biology_tweet_285,"the fingerprint sensor 
its activator domain contains the sites for function in multiple contexts despite the sixth finger👆lead to a hypothesized network of contextual connections
and the region near basic tail shares.\ The transactivation domain... ",This enabled the fine patterns of transparent electrodes required in fingerprint sensors that need to detect the period between the ridges and valleys of human fingers (~100 μm) .,"the fingerprint sensor 
its activator domain contains the sites for function in multiple contexts despite the sixth finger👆lead to a hypothesized network of contextual connections
and the region near basic tail shares.\ The transactivation domain... ","On the other hand, the AgNF-AgNW hybrid structure exhibited a negligible dependence of R s on the pattern widths, and it had a significantly low R s even for narrow patterns with widths <100 μm. This enabled the fine patterns of transparent electrodes required in fingerprint sensors that need to detect the period between the ridges and valleys of human fingers (~100 μm) . Figure 2f shows the relative change in resistance of the AgNF-AgNW hybrid electrode that was formed on a c-PI film (thickness: 25 μm) as a function of the radius of curvature and the corresponding bending-induced strain (ε).","[4.0, 4.0, 3.0]",Biology,train,3.6666666666666665,tweets,1018216740050726912
10.1038/ncomms14514,Biology_tweet_286,"""Liquid-like"" semiconductor clusters from my group ","This mode hardening indicates the presence of a compressive strain in the NCs, which increases in magnitude with decreasing size.","""Liquid-like"" semiconductor clusters from my group ","5) . This mode hardening indicates the presence of a compressive strain in the NCs, which increases in magnitude with decreasing size. It must, however, be acknowledged that the LO phonon frequency can shift also due to the effect of phonon confinement in small crystallites, as shown by the classic work of Richter et al.","[1.0, 1.0, 1.0, 2.0, 1.0]",Biology,train,1.2,tweets,833706813069598720
10.1186/s12896-018-0443-0,Biology_tweet_287,@username bc i read your tweet about gluten. saw this article 2mins ago :    Possible to buy medics against celiac desease in 2021~,"The SDS gel showed four dominant protein bands, which all contained the refolded product.",@username bc i read your tweet about gluten. saw this article 2mins ago :    Possible to buy medics against celiac desease in 2021~,"4) . The SDS gel showed four dominant protein bands, which all contained the refolded product. Host cell proteins were only found to a small portion in the lowest band, indicating a high purity of the refolded product.","[1.0, 1.0, 1.0, 1.0, 1.0]",Biology,train,1.0,tweets,1046202273490243584
10.1016/j.neuron.2018.12.026,Biology_tweet_288,"Autism animal model zoo news: that elevated E-I ratio in your autistic (Fmr1-/y, Cntnap2−/−, 16p11.2 del/+, Tsc2+/−) mice? It's compensatory ","Fmr1 À/y mice show faster or broader spread of sensory-evoked activity in S1, suggesting a blurred whisker map (Arnett et al., 2014; , which we also observed in the form of increased tuning heterogeneity in each S1 column.","Autism animal model zoo news: that elevated E-I ratio in your autistic (Fmr1-/y, Cntnap2−/−, 16p11.2 del/+, Tsc2+/−) mice? It's compensatory ","Thus, increased cortical spiking is not broadly observed in ASD genotypes. Fmr1 À/y mice show faster or broader spread of sensory-evoked activity in S1, suggesting a blurred whisker map (Arnett et al., 2014; , which we also observed in the form of increased tuning heterogeneity in each S1 column. A simple synaptic conductance model explains why increased E-I conductance ratio does not generate stronger PSPs or more spiking in ASD mutants: in all 4 ASD genotypes, the decreases in inhibitory and excitatory conductances were precisely counterbalanced to maintain constant PSPs for Vm just below spike threshold.","[2.0, 2.0, 1.0, 3.0]",Biology,train,2.0,tweets,1087505256383156226
10.1016/j.cub.2018.06.016,Biology_tweet_29,Zebrafish are social. Check out this awesome paper about how they identified what neurons in the brain are responsible! ,Our data show that social engagement in zebrafish requires a behavioral visual stimulus provided by another socially engaged fish.,Zebrafish are social. Check out this awesome paper about how they identified what neurons in the brain are responsible! ,"Based on their anatomical location and gene expression patterns, these cells may be homologous to a population of lhx8-expressing, cholinergic basal forebrain neurons that is also found in mammals . Our data show that social engagement in zebrafish requires a behavioral visual stimulus provided by another socially engaged fish. We demonstrated that both pharmacological manipulation of dopaminergic systems and ablation of a portion of the ventral telencephalon produce predictable deficits in social behavior.","[4.0, 5.0, 2.0]",Biology,train,4.0,tweets,1022584174065082369
10.1073/pnas.1219361110,Biology_tweet_290,Size matters. Penis size and attraction correlations.  ,Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans.,Size matters. Penis size and attraction correlations.  ,"Surprisingly, larger penis size and greater height had almost equivalent positive effects on male attractiveness. Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans. More broadly, our results show that precopulatory sexual selection can play a role in the evolution of genital traits.","[3.0, 5.0, 4.0, 2.0]",Biology,train,3.5,tweets,322099951318495232
10.1098/rsbl.2014.0993,Biology_tweet_292,"Poetic study: At night, the many pollination drops glitter like diamonds in the full moonlight  ",To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations .,"Poetic study: At night, the many pollination drops glitter like diamonds in the full moonlight  ","The full moon is thus important for efficient pollination of E. foeminea both for pollinator navigation in the dark and for attraction to the cones. To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations . By contrast, we find no correlation between the phases of the moon and secretion of pollination drops in the sympatric but wind-pollinated E. distachya ( figure 2b) ).","[1.0, 1.0, 1.0, 2.0, 2.0]",Biology,train,1.4,tweets,595976864704921602
10.1126/scitranslmed.aaa8419,Biology_tweet_293,"Hyperammonemia syndrome from Ureaplasma infection (and other causes) in transplant patients, latest learnings from @username ! 🌟Click the thread to read the entire entry and to go back to the original question. 📌#meded #transplant @username @username @username 💡 ",We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum.,"Hyperammonemia syndrome from Ureaplasma infection (and other causes) in transplant patients, latest learnings from @username ! 🌟Click the thread to read the entire entry and to go back to the original question. 📌#meded #transplant @username @username @username 💡 ","This patient was shown to have systemic M. hominis infection . We performed PCR and found that residual BAL fluid and blood collected shortly before his death were positive for both M. hominis and U. parvum. On postoperative day 12, he developed mental status changes, and his ammonia concentration was 549 mM.","[3.0, 1.0, 1.0]",Biology,train,1.6666666666666667,tweets,1071076147096682498
10.1098/rsos.171474,Biology_tweet_294,"Look, video games don't kill people, #guns kill people. There have been 4 studies showing NO evidence that violent video games lead to violence (     #GunConrolNow",Measurement flexibility also extends to a number of outcome assessments employed in the gaming literature.,"Look, video games don't kill people, #guns kill people. There have been 4 studies showing NO evidence that violent video games lead to violence (     #GunConrolNow",Such a pattern could lead researchers to make the spurious claim that playing the 2004 Xbox game Spider Man 2 is a significant catalyst for adolescent promiscuity . Measurement flexibility also extends to a number of outcome assessments employed in the gaming literature. A similar tractability is present in behavioural measurements of aggression.,"[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,tweets,1159861083047260160
10.1038/s41590-018-0068-4,Biology_tweet_295,"New paper from our lab out today in @username showing how #vitaPAMP recognition via TLR8 promotes #TFHcell differentiation &amp; #vaccine responses. 
Free full text  
","Further subgroup analysis revealed that distribution of the TLR8 allele was in fact significantly different only for subjects who had previously received the live BCG vaccine against TB (P = 0.002), whereas its distribution was not significantly different for unvaccinated subjects (P = 0.754) (Fig.","New paper from our lab out today in @username showing how #vitaPAMP recognition via TLR8 promotes #TFHcell differentiation &amp; #vaccine responses. 
Free full text  
","8a and Supplementary Table 3 ), indicative of a protective effect of TLR8-G against PTB, as has been reported 32 . Further subgroup analysis revealed that distribution of the TLR8 allele was in fact significantly different only for subjects who had previously received the live BCG vaccine against TB (P = 0.002), whereas its distribution was not significantly different for unvaccinated subjects (P = 0.754) (Fig. In this study, vaccination with BCG was associated with significant risk protection in carriers of the TLR8-G allele (odds ratio = 0.280 [95% confidence interval, 0.105-0.742]) but not in carriers of the TLR8-A allele ( Fig.","[3.0, 5.0, 5.0]",Biology,train,4.333333333333333,tweets,975784883288203264
10.1038/nature24621,Biology_tweet_296,"Wow, full-throated endorsement that ""Exact sequence variants should replace OTUs..."" in the EMP paper! ","While earlier largescale 16S rRNA amplicon studies adopted OTU clustering approaches in part out of concern that erroneous reads would dominate diversity assessments 23 , patterns of prevalence (presenceabsence) in our results suggest that Deblur error removal produced ecologically informative sequences without clustering.","Wow, full-throated endorsement that ""Exact sequence variants should replace OTUs..."" in the EMP paper! ","Because exact sequences are stable identifiers, unlike OTUs, they can be compared to any 16S rRNA or genomic data base now and in the future, thereby promoting reusability 22 . While earlier largescale 16S rRNA amplicon studies adopted OTU clustering approaches in part out of concern that erroneous reads would dominate diversity assessments 23 , patterns of prevalence (presenceabsence) in our results suggest that Deblur error removal produced ecologically informative sequences without clustering. After rarefying to 5,000 sequences per sample, a total of 307,572 unique sequences were contained in the 96 studies and 23,828 samples of the 'QCfiltered' Deblur 90bp observation table.","[2.0, 4.0, 2.0, 2.0]",Biology,train,2.5,tweets,926454748353564672
10.1038/s41467-018-04408-0,Biology_tweet_297,"Lower Testosterone Levels May Be Linked to Greater Lupus Risk in Women, Study Finds ","Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig.","Lower Testosterone Levels May Be Linked to Greater Lupus Risk in Women, Study Finds ","Indeed, Tnfsf13b (Baff) mRNA in the spleen was increased in G-ARKO mice (Fig. Further, a physiological testosterone replacement reduced spleen levels of Baff mRNA in castrated control but not G-ARKO mice (Fig. 3e) ; thus, testosterone downregulates splenic Baff mRNA in an AR-dependent manner.","[1.0, 2.0, 1.0, 1.0]",Biology,train,1.25,tweets,1009830063162974209
10.1038/s41467-017-01957-8,Biology_tweet_299,Again a fantastic study from those labs. Trade offs are dynamic and affect #Diversity  in #coevolution systems. ,"Furthermore, coevolved ciliates had a significantly higher growth rate compared to the ancestral ciliates at a given coevolved bacteria population ( Fig.",Again a fantastic study from those labs. Trade offs are dynamic and affect #Diversity  in #coevolution systems. ,"1a , Kruskal-Wallis ancestral vs. coevolved bacteria: χ 2 = 6.2, df = 1, p = 0.005). Furthermore, coevolved ciliates had a significantly higher growth rate compared to the ancestral ciliates at a given coevolved bacteria population ( Fig. 1b-d , coevolved bacteria population 1: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 5.4, df = 1, p = 0.007; bacteria population 2: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 5.4, df = 1, p = 0.007; bacteria population 3: Kruskal-Wallis ancestral vs. coevolved ciliate: χ 2 = 4.3, df = 1, p = 0.025).","[4.0, 3.0, 2.0, 3.0]",Biology,train,3.0,tweets,940647297108664326
10.14814/phy2.13617,Biology_tweet_3,#Sleep #LightAtNight  Sensitivity of the circadian system to evening bright light in preschool‐age children.  ,Findings from this study indicated that school-age children were almost twice as sensitive to the melatonin suppression effects of evening moderate bright light exposure (~580 lux) than their parents .,#Sleep #LightAtNight  Sensitivity of the circadian system to evening bright light in preschool‐age children.  ,"Findings from this study mark an important step in addressing a gap in understanding the melatonin suppression response across the lifespan. Findings from this study indicated that school-age children were almost twice as sensitive to the melatonin suppression effects of evening moderate bright light exposure (~580 lux) than their parents . Additionally, based upon an objective measure of pubertal development ), Crowley and colleagues found that that prepubertal adolescents (Tanner stage 1-3) were more sensitive to the suppressive effects of evening light on melatonin than postpubertal adolescents (Tanner stage 4-5) .","[5.0, 3.0, 4.0, 3.0]",Biology,train,3.75,tweets,992419683361067008
10.1038/s41467-018-04355-w,Biology_tweet_30,Factor XIIIA-Expressing Inflammatory Monocytes Promote Lung Squamous Cancer through Fibrin Cross-Linking @username @username @username ,"Notably, we show that IMs highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for LUSC cell invasion and metastases.",Factor XIIIA-Expressing Inflammatory Monocytes Promote Lung Squamous Cancer through Fibrin Cross-Linking @username @username @username ,"Pharmacologic inhibition of IM recruitment had substantial anti-metastatic effects. Notably, we show that IMs highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for LUSC cell invasion and metastases. Consistently, human LUSC samples containing extensive crosslinked fibrin in the microenvironment correlated with poor survival.","[4.0, 5.0, 2.0]",Biology,train,4.0,tweets,1000506886788173824
10.1016/j.nutres.2019.03.004,Biology_tweet_31,#Study: #Walnut Consumption (2 Ounces/Day) May Afford #Breast #Cancer Protection via Altered #Gene Expression  More:  Attn: @username @username @username #food #health #nutrition #prevention,RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption.,#Study: #Walnut Consumption (2 Ounces/Day) May Afford #Breast #Cancer Protection via Altered #Gene Expression  More:  Attn: @username @username @username #food #health #nutrition #prevention,"Pathological studies confirmed that lumps were breast cancer in all women who remained in the trial. RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption. Ingenuity Pathway Analysis showed activation of pathways that promote apoptosis and cell adhesion, and inhibition of pathways that promote cell proliferation and migration.","[4.0, 3.0, 3.0, 2.0, 5.0]",Biology,train,3.4,tweets,1105538072635047936
10.1186/s40168-015-0071-z,Biology_tweet_32,Do breast milk glycans enrich beneficial bacteria in infant guts? @username finds a role for fucosyltransferase 2 ,"Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05).",Do breast milk glycans enrich beneficial bacteria in infant guts? @username finds a role for fucosyltransferase 2 ,"When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ). Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05). The aggregated secretor-fed infant samples were, on average, found to have significantly higher absolute levels of bifidobacteria (10 9 .0 /g feces versus 10","[4.0, 3.0, 2.0, 5.0, 2.0]",Biology,train,3.2,tweets,586546592968224768
10.1098/rsos.171474,Biology_tweet_33,New #RegisteredReport published in #RSOS by @username at the  @username and Netta Weinstein at @username explores the relationship between adolescents playing violent video games and their likelihood of behaving aggressively. Find out more at ,"The results provide confirmatory evidence that violent video game engagement, on balance, is not associated with observable variability in adolescents' aggressive behaviour.",New #RegisteredReport published in #RSOS by @username at the  @username and Netta Weinstein at @username explores the relationship between adolescents playing violent video games and their likelihood of behaving aggressively. Find out more at ,"This is among the first studies to test the effects of violent gaming on human aggression using a preregistered hypothesis-testing framework and the first to do so following the registered reports protocol. The results provide confirmatory evidence that violent video game engagement, on balance, is not associated with observable variability in adolescents' aggressive behaviour. A healthy ecosystem of exploratory and registered research reports will enable scientists to conduct metanalytic research to evaluate the inferences drawn from these methodologies.","[4.0, 5.0, 4.0]",Biology,train,4.333333333333333,tweets,1095663919308382208
10.1038/s41396-017-0042-4,Biology_tweet_34,"RT gp_pulipaka: Deposition Rates of 800 Million Airborne Viruses and Bacteria Above the Atmospheric Boundary Layer: Big Data Analysis. #BigData #DataScience #Analytics #HealthTech 
 ","The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere.","RT gp_pulipaka: Deposition Rates of 800 Million Airborne Viruses and Bacteria Above the Atmospheric Boundary Layer: Big Data Analysis. #BigData #DataScience #Analytics #HealthTech 
 ","Therefore, these relationships between the size fractions of the organic aerosols and the virus and bacteria deposition rates could be also determined by the origin of air masses. The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere. This provides a mechanism for maintaining the very high diversity of viruses, as well as bacteria observed at a local level but constrained globally, consistent with a seedbank model.","[4.0, 3.0, 4.0, 3.0]",Biology,train,3.5,tweets,987949298305380352
10.1186/s40168-015-0071-z,Biology_tweet_35,Mum's genes influence bub's microbiota: Babies of mothers with FUT2 gene mutation have less gut Bifidobacteria ,"When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ).",Mum's genes influence bub's microbiota: Babies of mothers with FUT2 gene mutation have less gut Bifidobacteria ,"Differences were seen between the five C-section-born infants and the 39 vaginally born infants, with C-section infants having much lower levels of bifidobacteria and Bacteroides, although the number of C-section infants was too low to draw any robust conclusions (Additional file 3: Figure S1 ). When grouped by the mothers' secretor status, differences were seen in the aggregated infants' gut microbiota ( Figure 2 ). Specifically, secretor-fed infants generally had higher relative amounts of Bifidobacterium (p < 0.05) and Bacteroides and lower levels of enterobacteria, clostridia, and streptococci (p < 0.05).","[4.0, 2.0, 4.0]",Biology,train,3.333333333333333,tweets,587800449857622018
10.1098/rstb.2017.0259,Biology_tweet_36,you might be surprised to learn about how American crows respond to dead conspecifics - interesting study (and blog post) by @username and @username  ,"If crows exhibit a danger response, we expect higher rates of alarm calling and recruitment coupled with lower rates of contact in contrast to heterospecifics.",you might be surprised to learn about how American crows respond to dead conspecifics - interesting study (and blog post) by @username and @username  ,"If such information acquisition motivates tactile interactions, we expect that interactions will be coupled with alarm calling and recruitment, be primarily non-aggressive in nature and occur frequently and uniformly across the study period. If crows exhibit a danger response, we expect higher rates of alarm calling and recruitment coupled with lower rates of contact in contrast to heterospecifics. We expect that the life-like crow will result in scolding and divebombing, but infrequent recruitment, and that contact will be primarily aggressive.","[1.0, 5.0, 2.0, 3.0]",Biology,train,2.0,tweets,1018892879404634112
10.1098/rsbl.2013.0620,Biology_tweet_37,Dr. G. Mills of WildCRU et al. show how cheetah hunting tactics vary according to their  prey via @username ,"Rather, we suggest that cheetah chases comprise two primary phases: (i) an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by (ii) a prey-specific slowing period that enables the cheetah to match turns instigated by prey as the distance between them closes.",Dr. G. Mills of WildCRU et al. show how cheetah hunting tactics vary according to their  prey via @username ,"Thus, the widely held belief that cheetah hunts consist of simple highspeed chases seems an oversimplification. Rather, we suggest that cheetah chases comprise two primary phases: (i) an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by (ii) a prey-specific slowing period that enables the cheetah to match turns instigated by prey as the distance between them closes. However, this formulation only considered forward acceleration and speed, ignoring lateral acceleration.","[4.0, 4.0, 4.0, 5.0]",Biology,train,4.25,tweets,375312376490647552
10.3945/jn.113.188441,Biology_tweet_38,"Beware the instant noodle! A marker of fast food dietary pattern in Korea,linked to obesity, high LDL &amp;triglycerides ","Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) .","Beware the instant noodle! A marker of fast food dietary pattern in Korea,linked to obesity, high LDL &amp;triglycerides ","In addition, the mean sodium intake was very high across all categories (age-standardized mean sodium intake: 6.0 g in men, 4.2 g in women). Participants who frequently consumed instant noodles ($2 times/wk) and those in the highest quintile of the MP were younger, more likely to be current smokers, drink more alcohol, be less physically active, and have low carbohydrate intake in both genders (Table 1) . Interestingly, although participants in the highest quintile of the MP had a higher education/income level than participants in the lowest quintile, frequent consumers of instant noodles had lower educational/income levels than did infrequent instant noodle consumers.","[2.0, 2.0, 2.0]",Biology,train,2.0,tweets,491425485352476673
10.1038/nature12167,Biology_tweet_39,first ever class F GPCR structure:  human SMO receptor with antagonist,"However, an overlay of the SMO receptor structure with previously solved class A GPCR structures shows relatively high spatial conservation of the 7TM bundle (Fig.",first ever class F GPCR structure:  human SMO receptor with antagonist,"Sequence similarity between the SMO receptor and class A GPCRs is very low (less than 10% sequence identity), and SMO and other class F receptors lack most of the conserved class A motifs, including D[E]R 3.50 Y in helix III, CWXP .50 in helix V and NP 7.50 XXY in helix VII (superscript numbers reflect the B&W numbering system for GPCRs 24 , brackets define an alternative residue and X denotes any residue). However, an overlay of the SMO receptor structure with previously solved class A GPCR structures shows relatively high spatial conservation of the 7TM bundle (Fig. 2a, b and Supplementary Fig.","[1.0, 3.0, 3.0, 2.0, 2.0]",Biology,train,2.2,tweets,329682457811116032
10.1126/sciadv.aaq0883,Biology_tweet_40,"Asylum seekers in Western Europe boost their host countries' economies over time, a new study in @username concludes:  ",We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies.,"Asylum seekers in Western Europe boost their host countries' economies over time, a new study in @username concludes:  ","Year 1 rather be an economic opportunity. We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies. However, these political challenges may be more easily addressed if the cliché that international migration is associated with economic ""burden"" can be dispelled.","[4.0, 2.0, 1.0, 2.0]",Biology,train,2.25,tweets,1009501290098053120
10.1038/s41467-018-05664-w,Biology_tweet_43,"Stepping towards universal #QuantumComputing. 

The universal holonomic gates enable fast and fault-tolerant manipulation for realising quantum repeaters interfacing between universal quantum computers and secure communication networks. 

 ",We also demonstrate a two-qubit holonomic gate to show universality by manipulating the electron−nucleus entanglement.,"Stepping towards universal #QuantumComputing. 

The universal holonomic gates enable fast and fault-tolerant manipulation for realising quantum repeaters interfacing between universal quantum computers and secure communication networks. 

 ","We also demonstrate a two-qubit holonomic gate to show universality by manipulating the electron−nucleus entanglement. The universal holonomic gates enable fast and fault-tolerant manipulation for realising quantum repeaters interfacing between universal quantum computers and secure communication networks. However, these experiments required microwaves 20 or light waves 24 in two frequencies differing by the energy gap for manipulating the nondegenerate subspace, leading to the degradation of gate fidelity due to the unwanted interference of the dynamic phase.","[3.0, 5.0, 3.0, 3.0]",Biology,train,3.5,tweets,1029120219912986624
10.1016/j.molcel.2014.05.030,Biology_tweet_44,"RESEARCH: More light shed on #melanoma development #skincancer #sunscreen #tanning 

--","Though MC1R dysfunction is clearly linked with defective tanning , MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation .","RESEARCH: More light shed on #melanoma development #skincancer #sunscreen #tanning 

--","R151C, R160W and D294H) exhibit a fair-skinned sun-sensitive phenotype and have up to a four-fold increased lifetime risk of melanoma . Though MC1R dysfunction is clearly linked with defective tanning , MC1R signaling also protects melanocytes against carcinogenesis independent of pigmentation . ATR (ATM and Rad3-related) is critical to UV DNA damage signaling and is intimately linked with NER (Bomgarden et al., 2006; .","[4.0, 4.0, 3.0, 3.0]",Biology,train,3.5,tweets,489055446037049344
10.1016/j.neuron.2014.04.039,Biology_tweet_45,β-Amyloid inhibits E-S potentiation through suppression of cannabin... - PubMed - NCBI ,The present discovery of an explicit role for Ab in suppressing cannabinoid function elucidates a substrate of Alzheimer's pathology.,β-Amyloid inhibits E-S potentiation through suppression of cannabin... - PubMed - NCBI ,"The mechanism by which Ab disables the effects of cannabinoids on synaptic inhibition, and thus disrupts plasticity, may explain learning and memory deficits in AD that occur in otherwise healthy neural circuits prior to AD-related neuronal cell death. The present discovery of an explicit role for Ab in suppressing cannabinoid function elucidates a substrate of Alzheimer's pathology. Thus, this newfound knowledge may advance understanding of the causes of Alzheimer's symptomatology and open new avenues for therapeutic intervention and improvement not only for memory in the earlier stages of the disease, but for the progression of the disease itself.","[4.0, 4.0, 3.0, 2.0, 2.0]",Biology,train,3.0,tweets,532250326435262464
10.1126/sciadv.aau1291,Biology_tweet_46,RT @username This makes much sense! why exposing the entire body every single day in a person that only has focal seizures from time to time? this local delivery of drug to the source of the seizure would be an excellent choice in #epilepsy (from @username) ,The FIP probe can detect pathological activity and then intervene to stop seizures by delivering inhibitory neurotransmitters directly to the seizure source.,RT @username This makes much sense! why exposing the entire body every single day in a person that only has focal seizures from time to time? this local delivery of drug to the source of the seizure would be an excellent choice in #epilepsy (from @username) ,The therapeutic potential of the FIP probe is tested in a rodent model of epilepsy. The FIP probe can detect pathological activity and then intervene to stop seizures by delivering inhibitory neurotransmitters directly to the seizure source. We anticipate that further tailored engineering of the FIP platform will enable additional applications in neural interfacing and the treatment of neurological disorders.,"[3.0, 5.0, 3.0, 5.0, 2.0]",Biology,train,3.0,tweets,1035088610830299137
10.1038/s41589-018-0155-8,Biology_tweet_47,"EVIDENCE: Newly developed inhibitor of ADBH12, DO264 is shown to result in elevated lyso-PS levels in mice without loss of auditory function associated with ADBH12 knockout. 
@username
#4bb3neuroimmune",We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig.,"EVIDENCE: Newly developed inhibitor of ADBH12, DO264 is shown to result in elevated lyso-PS levels in mice without loss of auditory function associated with ADBH12 knockout. 
@username
#4bb3neuroimmune","), which adopt a more macrophage-like cell state compared to undifferentiated THP-1 cells. We also found that DO264 inhibits ABHD12 activity ( Supplementary Fig. 16 ) and alters lyso-PS and PS content in primary human macrophages, which showed elevations in both lyso-PS and 20:4 PS following 4 or 24 h treatment with DO264 (1 µ M), but not (S)-DO271 (1 µ M) ( Fig.","[3.0, 4.0, 2.0, 1.0, 3.0]",Biology,train,2.6,tweets,1067703178148438021
10.1111/gcb.13526,Biology_tweet_48,Leaves suck? Yield boost in soybean seen by cutting leaves off.  ,The predicted gains in yield were primarily due to decreased investment in leaves allowing predicted increase in seed production.,Leaves suck? Yield boost in soybean seen by cutting leaves off.  ,"The model therefore predicts that the additional two units of LAI above the model predicted optimum would not significantly contribute to net carbon gain, as photosynthesis roughly compensated for respiratory costs (Fig. The predicted gains in yield were primarily due to decreased investment in leaves allowing predicted increase in seed production. However, as LAI is lowered below the optimum value, predicted losses in NPP become significant to the detriment of seed production.","[4.0, 4.0, 4.0, 4.0, 4.0]",Biology,train,4.0,tweets,799736439458111488
10.1126/sciadv.1501675,Biology_tweet_49,"Using #satellite #remotesensing to track and prevent loss of critical  #tiger habitat. Via @username @username
","This suggests that if future habitat loss is prevented, the tiger recovery now underway in some range states will accelerate.","Using #satellite #remotesensing to track and prevent loss of critical  #tiger habitat. Via @username @username
","Most encouraging was that loss was less than expected in the 51 tiger reserves that serve as source sites in the priority landscapes. This suggests that if future habitat loss is prevented, the tiger recovery now underway in some range states will accelerate. In these promising locales of enhanced protection, a doubling of the tiger population could be attainable by 2022.","[2.0, 2.0, 5.0, 2.0, 4.0]",Biology,train,2.0,tweets,715976728561192960
10.1016/j.cmet.2015.02.003,Biology_tweet_5,Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin: submitted by  srepen  [link]... ,Large amounts of Na + are stored in the skin.,Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin: submitted by  srepen  [link]... ,Na + metabolism may represent an unappreciated functional component of skin barrier formation. Large amounts of Na + are stored in the skin. This age-dependent Na + accumulation is associated with primary (essential) and secondary hypertension .,"[5.0, 5.0, 4.0, 2.0]",Biology,train,4.0,tweets,577605484863066112
10.1038/s41598-019-39601-8,Biology_tweet_50,new paper published today in @username from my undergraduate work with lab mates at @username &amp; @username! we asked: how do functional traits (related to sex &amp; species) mediate the effect of urbanization on wild bees? ,Analyses show no qualitative differences with bumble bees removed: OSR still becomes less female-biased as urbanization increases (Table S3 ).,new paper published today in @username from my undergraduate work with lab mates at @username &amp; @username! we asked: how do functional traits (related to sex &amp; species) mediate the effect of urbanization on wild bees? ,"made up a large portion of our sample set; most bumble bee species are eusocial, and as such may experience controls on OSR that differ substantially from other bees (see Introduction). Analyses show no qualitative differences with bumble bees removed: OSR still becomes less female-biased as urbanization increases (Table S3 ). As with bee abundance data, floral richness and area metrics were significantly overdispersed, so quasi-Poisson distributions were used to account for overdispersion.","[3.0, 3.0, 3.0]",Biology,train,3.0,tweets,1103310660925038592
10.1016/j.neuron.2013.09.021,Biology_tweet_51,RNAi in songbirds to study the involvment of FoxP2 in song variability in @username ,"Therefore, reducing FoxP2 levels in Area X abolishes context-dependent changes in both LMAN singing-related activity and song variability.",RNAi in songbirds to study the involvment of FoxP2 in song variability in @username ,"Finally, both the mean firing rates and levels of bursting activity of LMAN neurons recorded in the directed state were significantly higher in the LV-ShFoxP2 birds (Figures 6D and 6E ; p = 0.006 and p = 0.013, respectively). Therefore, reducing FoxP2 levels in Area X abolishes context-dependent changes in both LMAN singing-related activity and song variability. Notably, the AFP affects syllable variability through the synapses that LMAN axons make on RA neurons (Ö lveczky et al., 2005) , and the variability of action potential timing in RA neurons can account for a significant fraction of acoustic variation in the bird's song .","[3.0, 3.0, 3.0, 3.0, 4.0]",Biology,train,3.2,tweets,408349111281131521
10.3945/jn.113.188441,Biology_tweet_52,"Limit the Ramen: Instant noodles linked to heart risk in women

Abstract: ","In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity.","Limit the Ramen: Instant noodles linked to heart risk in women

Abstract: ","Even though measurements of the glycemic index of instant noodles varied among studies , the overall glycemic load of instant noodles is high, given their high carbohydrate content ( ( . In our study, the association between instant noodles and metabolic syndrome differed significantly between genders, and there was no effect modification of this association by age, BMI, or physical activity. The positive association between instant noodles and metabolic syndrome seen in younger, more active, and leaner women suggests that the hazards of instant noodles might not be overcome by the beneficial health effects of increased physical activity, weight loss, and young age.","[3.0, 3.0, 2.0, 4.0, 3.0]",Biology,train,3.0,tweets,502439920238333952
10.1016/j.cub.2018.06.016,Biology_tweet_54,"How does the brain control social interactions? @username et al. from @username show forebrain control of visually mediated social orienting in #zebrafish.
 ",We conclude from these results that another socially engaged fish is the stimulus required for social orienting and that the presence of another fish that is not socially engaged is insufficient regardless of their proximity.,"How does the brain control social interactions? @username et al. from @username show forebrain control of visually mediated social orienting in #zebrafish.
 ","We placed apo-treated fish in a shortened tank that restricted their movement away from the divider and found that test fish exposed to apo-treated stimulus fish still had suppressed social orienting relative to controls (Figures  2A-2D ; p = 0.009, n = 26). We conclude from these results that another socially engaged fish is the stimulus required for social orienting and that the presence of another fish that is not socially engaged is insufficient regardless of their proximity. Orientation of the test fish and distance of the stimulus fish are highly correlated (R 2 = 0.302, p < 0.001), as is the orienting behavior of the stimulus fish (R 2 = 0.458, p < 0.001; Figures 2E and 2F ).","[3.0, 5.0, 2.0, 2.0, 3.0]",Biology,train,3.0,tweets,1022743856125763585
10.1186/s40168-015-0071-z,Biology_tweet_55,#humanmicrobiome David Mills- more bifidobacteria less glycans in baby's poop ,Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).,#humanmicrobiome David Mills- more bifidobacteria less glycans in baby's poop ,"Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ). Of 35 milks from non-secretors, 20 of the matched infant stool samples were Low-Bif qPCR (57.1%).","[4.0, 1.0, 4.0, 3.0]",Biology,train,4.0,tweets,616546067396579328
10.1093/jee/tou026,Biology_tweet_56,More evidence that the emerald ash borer attacks white fringetrees (Chionanthus virginicus ). White fringetrees... ,Infestation of ash trees by emerald ash borer became visibly apparent for the first time in the village and nearby areas in 2012 (personal observation).,More evidence that the emerald ash borer attacks white fringetrees (Chionanthus virginicus ). White fringetrees... ,"White fringetree is in the same family as ash trees, and planted individuals and wild populations will come increasingly in contact with emerald ash borer as it spreads to the southeastern United States. Infestation of ash trees by emerald ash borer became visibly apparent for the first time in the village and nearby areas in 2012 (personal observation). On 17 August 2014, I found that one of the white fringetrees along the trail ( Fig.","[2.0, 2.0, 4.0]",Biology,train,2.6666666666666665,tweets,555801187736621056
10.1016/j.bpj.2013.12.017,Biology_tweet_59,A BPJ paper finds that the appearance of #Lymedisease rash can help predict how bacteria spreads through body ,"Activation of the innate immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within~1 week.",A BPJ paper finds that the appearance of #Lymedisease rash can help predict how bacteria spreads through body ,"2 g shows a radial slice through a simulated central erythema and shows how the spirochete and macrophage populations change as the rash progresses. Activation of the innate immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within~1 week. Therefore, the rash grows, but the center becomes less inflamed.","[2.0, 4.0, 2.0, 4.0]",Biology,train,3.0,tweets,430754817363804161
10.1083/jcb.201710132,Biology_tweet_6,"Messenger et al. show that exosome secretion in cancer cells is Ca2+-stimulated and dependent on Ca2+-bound Munc13-4. Munc13-4, a late endosome priming factor, acts via a Rab11-dependent pathway to prepare multivesicular endosomes for exocytosis  ","We propose that the increased expression of Munc13-4 in cancer cells after epithelial-to-mesenchymal transition combined with increased Ca 2+ uptake drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention.","Messenger et al. show that exosome secretion in cancer cells is Ca2+-stimulated and dependent on Ca2+-bound Munc13-4. Munc13-4, a late endosome priming factor, acts via a Rab11-dependent pathway to prepare multivesicular endosomes for exocytosis  ","This Ca 2+ -, Munc13-4-, and Rab11dependent pathway generated secretion-competent MVBs for basal and Ca 2+ -stimulated CD63 + exosome release. We propose that the increased expression of Munc13-4 in cancer cells after epithelial-to-mesenchymal transition combined with increased Ca 2+ uptake drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention. The acute (30-min) elevation of intracellular Ca 2+ with ionomycin treatment enhanced CD63 + , CD9 + , and ALIX + exosome release by approximately fivefold in control MDA-MB-231 cells (Fig.","[4.0, 4.0, 4.0, 4.0]",Biology,train,4.0,tweets,1012681596258934793
10.1038/ng.955,Biology_tweet_60,Discovery of a rare BRIP1 mutation (0.4% freq) that has  &gt;800% increase risk of ovarian cancer  ,"Ovarian tumors from BRIP1 mutation carriers show loss of the wild-type allele, suggesting that the BRIP1 gene behaves like a classical tumor suppressor gene in ovarian cancer and that tumors with bi-allelic loss of BRIP1 may be good targets for therapeutic agents that affect DNA repair pathways.",Discovery of a rare BRIP1 mutation (0.4% freq) that has  &gt;800% increase risk of ovarian cancer  ,"Furthermore, the lives of BRIP1 mutation carriers are on average 3.6 years shorter than those of non-carriers. Ovarian tumors from BRIP1 mutation carriers show loss of the wild-type allele, suggesting that the BRIP1 gene behaves like a classical tumor suppressor gene in ovarian cancer and that tumors with bi-allelic loss of BRIP1 may be good targets for therapeutic agents that affect DNA repair pathways. Because of the relatively low prevalence of ovarian cancer, apparently sporadic cases may actually be caused by rare mutations that have large effects.","[2.0, 2.0, 4.0, 4.0]",Biology,train,3.0,tweets,120644384592105473
10.1038/s41467-018-04408-0,Biology_tweet_61,Testosterone Is an Endogenous Regulator of BAFF &amp; Splenic B Cell Number @username @username ,"Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function.",Testosterone Is an Endogenous Regulator of BAFF &amp; Splenic B Cell Number @username @username ,"Hence, estradiol elevates BAFF production and accelerates autoimmune disease , whereas testosterone has the opposite effects . Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function. In conclusion, our study uncovers a previously unrecognized regulation of BAFF by testosterone.","[1.0, 3.0, 2.0, 3.0]",Biology,train,2.25,tweets,1004493164055597058
10.1111/1365-2656.12871,Biology_tweet_64,"Disease dynamics of viral biocontrol agents against invasive rabbits: myxoma virus (MYXV) may reduce the future survival rates of individuals that endure initial MYXV infection, paving the way for RHDV to more efficiently kill rabbits
 ","Relatively constant rates of RHDV-and MYXV-induced mortality and infection rates over time are likely to be the result of strongly coupled coevolutionary changes in host resistance and tolerance and pathogen invasiveness, each working to keep the other at bay.","Disease dynamics of viral biocontrol agents against invasive rabbits: myxoma virus (MYXV) may reduce the future survival rates of individuals that endure initial MYXV infection, paving the way for RHDV to more efficiently kill rabbits
 ","However, this is despite the viruses having devastating impacts on rabbit survival when the epidemics first occurred, likely because initial disease dynamics are often transient and differ from long-term outcomes ). Relatively constant rates of RHDV-and MYXV-induced mortality and infection rates over time are likely to be the result of strongly coupled coevolutionary changes in host resistance and tolerance and pathogen invasiveness, each working to keep the other at bay. It might be that virulence of both viruses in the study population is being maintained at an optimum (assuming that viruses track changes in host resistance as they are capable of fast selection and genetic changes due to fast replication), which is most efficient for viral spread.","[3.0, 3.0, 3.0, 4.0]",Biology,train,3.25,tweets,1016951622461603840
10.1038/s41467-018-04373-8,Biology_tweet_65,"Great job &amp; Interesting results! Cytoplasmic SFPQ is in normal axon, where essential for motor function.      So, on top of nuclear loss, perturbation of axonal function may contribute to ALS intron pathology. Watch that space! ","The most significant intron-retaining transcript across VCP mu , SOD1 mu and FUS mu iPSC models was SFPQ, which encodes a protein that plays key roles in salient ALS-related pathways including RNA transcription, splicing, 3′ end processing and axon viability .","Great job &amp; Interesting results! Cytoplasmic SFPQ is in normal axon, where essential for motor function.      So, on top of nuclear loss, perturbation of axonal function may contribute to ALS intron pathology. Watch that space! ","These findings together raise the hypothesis that aberrant IR represents subtle manifestations of a dysregulated pathway of the developing neurons, which eventually contributes to the increased vulnerability of mature MNs. The most significant intron-retaining transcript across VCP mu , SOD1 mu and FUS mu iPSC models was SFPQ, which encodes a protein that plays key roles in salient ALS-related pathways including RNA transcription, splicing, 3′ end processing and axon viability . Subsequent experiments showed that the intron-retaining transcript is more abundant in the cytoplasm of VCP mu compared to control counterparts, and coincides with nuclear decrease of the SFPQ protein.","[2.0, 4.0, 3.0, 3.0]",Biology,train,3.0,tweets,1000144648751460353
10.1038/ncomms4081,Biology_tweet_66,Synthetic self-propelled swimming bio-bots:  (powered by cardiomyocytes) ,"The study thus provides a foundation for a new class of self-propelled, batch-fabricable, soft biological swimming machines.",Synthetic self-propelled swimming bio-bots:  (powered by cardiomyocytes) ,"Although only cardiomyocytes are used as contractile cells in this work, the method is applicable to other homotypic cell types, such as optogenetic muscle cells for light-actuated swimming, or heterotypic cells types, such as turtle cardiomyocytes and fibroblasts for room temperature swimming, and neurons and muscle cells for sensing-based intelligent swimming. The study thus provides a foundation for a new class of self-propelled, batch-fabricable, soft biological swimming machines. The cross-section of the channel determines the shape of the PDMS filament.","[4.0, 4.0, 5.0, 5.0]",Biology,train,4.5,tweets,425687584958726144
10.1373/clinchem.2012.187617,Biology_tweet_67,"The gut #microbiome and #metabolism: implications for #obesity, #diabetes  #HMP #DNA #nutrition",These human studies confirmed animal data suggesting that alterations in gut microbial composition are associated with obesity.,"The gut #microbiome and #metabolism: implications for #obesity, #diabetes  #HMP #DNA #nutrition","After weight loss, increased amounts of Bacteroidetes (3% to 15%) and a decreased abundance of Firmicutes were observed, and these changes correlated with the percentage of weight loss and not with changes in dietary caloric content. These human studies confirmed animal data suggesting that alterations in gut microbial composition are associated with obesity. This report documented an abundance of Bifidobacterium taxa and decreased proportions of Staphylococcus aureus in children who were whose weight was within reference intervals at age 7 years than in those who were overweight or obese.","[5.0, 3.0, 4.0]",Biology,train,4.0,tweets,336505689545515008
10.1016/j.celrep.2014.05.030,Biology_tweet_68,NUCKS levels inversely correlate with obesity in humans and mice ,"Together, these results, especially the finding that nutrient overload exacerbates the metabolic phenotypes in the absence of NUCKS, suggest that NUCKS plays a role in metabolic homeostasis in vivo.",NUCKS levels inversely correlate with obesity in humans and mice ,"Consistent with the obese phenotype, leptin levels were elevated while those of adiponectin were decreased in HFD-fed NUCKS KO mice ( Figure S3G and S3H) . Together, these results, especially the finding that nutrient overload exacerbates the metabolic phenotypes in the absence of NUCKS, suggest that NUCKS plays a role in metabolic homeostasis in vivo. There was no difference in resting or fasting glucose levels between the two groups, but resting insulin levels were higher in NUCKS KO mice compared with WT mice (Figures S4A and S4B ; data not shown).","[3.0, 4.0, 4.0]",Biology,train,3.6666666666666665,tweets,484952704184115200
10.1002/stem.2883,Biology_tweet_7,Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency.  ,Together our data indicate that light responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at the scale needed for pharmacology and drug screening purposes.,Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency.  ,"We tested the response of iPSC-derived retinal organoids to Moxifloxacin and showed that similarly to in vivo adult mouse retina, the primary affected cell types were photoreceptors. Together our data indicate that light responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at the scale needed for pharmacology and drug screening purposes. Hallam and colleagues show herein that generation of retinal organoids from human iPSC is efficient, reliable and scalable.","[3.0, 1.0, 3.0, 4.0]",Biology,train,2.75,tweets,1018079131395751936
10.1038/s41467-018-06087-3,Biology_tweet_70,"New from colleagues at BristolChem ""Antagonistic chemical coupling in self-reconfigurable host-guest protocells.""  #chemistry #bristol",Self-reconfiguration of host-guest protocells containing spatially separated GOx and HRP produced multi-enzyme vesicle-inproteinosome nested microstructures.,"New from colleagues at BristolChem ""Antagonistic chemical coupling in self-reconfigurable host-guest protocells.""  #chemistry #bristol","For example, internalisation of the fatty acid vesicles within the proteinosomes resulted in a 1.7 to 2.6-fold accumulation of positively charged, low-molecular weight solutes (RITC-HRP, αdansyl-L-arginine or RITC-labelled Mb) compared with the external continuous phase (Fig. Self-reconfiguration of host-guest protocells containing spatially separated GOx and HRP produced multi-enzyme vesicle-inproteinosome nested microstructures. Whereas GOx was retained within the aqueous phase of the released proteinosomes, HRP was entrapped specifically within the guest vesicles (Fig.","[2.0, 3.0, 2.0, 3.0]",Biology,train,2.5,tweets,1038729276168777728
10.1098/rsos.180695,Biology_tweet_72,"When we go home, we like to make an indoor climate like our ancestral home in Eastern Africa
New study in Royal Society Open Science  
Inside Science story  
Read more on climate adaptations in my book   ","Overall, we identified the geographical distribution of the global outdoor climate that is most similar to the interiors of our study homes and summarized study home indoor climate preferences.","When we go home, we like to make an indoor climate like our ancestral home in Eastern Africa
New study in Royal Society Open Science  
Inside Science story  
Read more on climate adaptations in my book   ","We found that the indoor climates of our study homes largely matched the TNZ of humans and other primates. Overall, we identified the geographical distribution of the global outdoor climate that is most similar to the interiors of our study homes and summarized study home indoor climate preferences. It would be difficult to convincingly argue that the behaviours leading to the construction of human houses are under direct selection.","[3.0, 4.0, 4.0, 2.0, 2.0]",Biology,train,3.0,tweets,1108345524942331904
10.1073/pnas.1504869112,Biology_tweet_73,Vines (lianas) reduce carbon storage in tropical forests. New paper from @username  ,"The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests.",Vines (lianas) reduce carbon storage in tropical forests. New paper from @username  ,"Liana-tree competition can be far more intense than tree-tree competition (3), substantially reducing tree growth , fecundity , and survival . The increase in lianas, combined with the observations that lianas can reduce individual tree growth by up to 84% and increase tree mortality risk two-to three-fold , has made it pertinent to investigate the effect of lianas on forest-level biomass dynamics to better predict the effect of increasing liana abundance on tropical forests. These studies indicated that the presence of lianas can reduce stand-level biomass growth by ∼10% and net forest biomass accumulation by up to 18% and that forest carbon stocks decrease with increasing liana abundance ( .","[4.0, 3.0, 3.0, 3.0, 2.0]",Biology,train,3.0,tweets,654294456770932736
10.1098/rsos.171474,Biology_tweet_74,"The best available evidence: ""We argue that this study speaks to the key question of whether adolescents’ violent video game play has a measurable effect on real-world aggressive behaviour  On the basis of our evidence, the answer is no.""  ",There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour.,"The best available evidence: ""We argue that this study speaks to the key question of whether adolescents’ violent video game play has a measurable effect on real-world aggressive behaviour  On the basis of our evidence, the answer is no.""  ","Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function. There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour. Sensitivity and exploratory analyses indicated these null effects extended across multiple operationalizations of violent game engagement and when the focus was on another behavioural outcome, namely, prosocial behaviour.","[3.0, 5.0, 5.0, 5.0, 4.0]",Biology,train,4.4,tweets,1095725862748651521
10.3945/jn.113.188441,Biology_tweet_75,Instant noodle intake and dietary patterns are associ... [J Nutr. 2014] - PubMed - NCBI ,"Dietary pattern and cardiometabolic risk factors 1249 adjustment by instant noodle intake attenuated the overall association between MP and abdominal obesity; however, the association between MP and abdominal obesity in men and the overall associations among MP and LDL cholesterol, HDL cholesterol, and hypertriglyceridemia persisted.",Instant noodle intake and dietary patterns are associ... [J Nutr. 2014] - PubMed - NCBI ,"Interestingly, there was a lower prevalence of low HDL cholesterol (OR: 0.; 9% CI: 0., 0.80) and TGs $10 mg/dL (1. g/L) (OR: 0.; 9% CI: 0., 0.9) in the highest MP quintile. Dietary pattern and cardiometabolic risk factors 1249 adjustment by instant noodle intake attenuated the overall association between MP and abdominal obesity; however, the association between MP and abdominal obesity in men and the overall associations among MP and LDL cholesterol, HDL cholesterol, and hypertriglyceridemia persisted. The highest TP quintile was associated with a lower prevalence of elevated blood pressure (OR: 0.73; 95% CI: 0.59, 0.90) and marginally lower trends for abdominal obesity (OR: 0.76; 95% CI: 0.58, 0.98; P-trend = 0.06) compared with the lowest quintile ( Table 4 ).","[2.0, 2.0, 2.0, 3.0]",Biology,train,2.25,tweets,520940730765025281
10.1073/pnas.1504869112,Biology_tweet_76,really interesting finding that lianas reduce total ecosystem #carbon uptake and storage in tropical #forests ,"Likewise, a potential liana-driven shift in tree species composition may also alter long-term biomass carbon storage if the presence of lianas leads to an increase in fast-growing trees with low wood densities, as is predicted .",really interesting finding that lianas reduce total ecosystem #carbon uptake and storage in tropical #forests ,"Long-term Submission PDF biomass carbon storage may be further reduced if increasing liana biomass intensifies liana-tree competition and/or increases the proportion of trees that are competing with lianas. Likewise, a potential liana-driven shift in tree species composition may also alter long-term biomass carbon storage if the presence of lianas leads to an increase in fast-growing trees with low wood densities, as is predicted . Nevertheless, our simulation provides an initial conservative estimate of the potential long-term effect of lianas on forest-level carbon stocks.","[5.0, 3.0, 2.0]",Biology,train,3.0,tweets,656251720243154944
10.3945/jn.113.188441,Biology_tweet_77,What's a college student to do? Instant noodle intake associated with cardiometabolic risk factors. ,"The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ).",What's a college student to do? Instant noodle intake associated with cardiometabolic risk factors. ,"The exclusion of participants taking blood pressurelowering or lipid-lowering medications or who had a history of diabetes mellitus did not change the overall associations between dietary patterns and cardiometabolic risk factors. The consumption of instant noodles $2 times/wk was associated with a higher prevalence of metabolic syndrome in women [OR: 1.68; 95% CI: 1.10, 2.55; P-trend < 0.01, P-interaction (gender 3 instant noodle intake) = 0.04] and marginally higher abdominal obesity in women (OR: 1.48; 95% CI: 0.99, 2.21; Ptrend = 0.06) but not in men ( Table 5 ). Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men.","[4.0, 2.0, 4.0, 4.0]",Biology,train,3.5,tweets,486612022608789505
10.1186/s40168-015-0071-z,Biology_tweet_78,Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities…  #microbiome ,Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community.,Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities…  #microbiome ,"The distribution of the qPCR data was bimodal, with a large group of samples with low levels of bifidobacteria (<10 7.6 /g feces, average 10 6.1 ) and a separate group with high amounts of bifidobacteria (>10 8.9 /g feces, average 10 10.3 ), with a striking lack of values falling in between the two ranges ( Figure 4 ). Much of the bifidobacterial abundance difference between the two secretor status milk phenotypes appears to come from variation in the time at which each infant transitions from possessing a Low-Bif qPCR ' gut community to possessing a High-Bif qPCR gut community. Bifidobacteria were found to be established (High-Bif qPCR ) earlier in secretorfed infants (60% of infants versus 37.5% at day 6) and more often (80% versus 50% by day 120) ( Figure 5 ).","[2.0, 4.0, 2.0, 2.0, 2.0]",Biology,train,2.4,tweets,593723617617149952
10.1111/gcb.13276,Biology_tweet_8,New tool to standardize and compare susceptibility of corals to thermal bleaching ,"Coral colonies, inhabiting the same reef and apparently exposed to identical conditions, will bleach and die at different rates Obura, 2001; .",New tool to standardize and compare susceptibility of corals to thermal bleaching ,"Within a bleaching event, coral susceptibility to stress is highly uneven. Coral colonies, inhabiting the same reef and apparently exposed to identical conditions, will bleach and die at different rates Obura, 2001; . Knowing which of many potential factors determine differential bleaching susceptibility among taxa will be essential to understanding bleaching mechanisms, and to preserve, manage, or reconstruct coral assemblages.","[2.0, 1.0, 4.0, 4.0]",Biology,train,2.0,tweets,720549155148537860
10.1016/j.cell.2018.05.009,Biology_tweet_80,Very cool work on pH dependent regulation of intracellular circadian rhythms. Pls don’t drink HCl to prevent cancer. ,Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation.,Very cool work on pH dependent regulation of intracellular circadian rhythms. Pls don’t drink HCl to prevent cancer. ,"Unexpectedly, we uncover a profound disruption of the circadian clock and diurnal transcriptome when hypoxic cells are permitted to acidify to recapitulate the tumor microenvironment. Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation. We find that acid drives peripheral redistribution of normally perinuclear lysosomes away from perinuclear RHEB, thereby inhibiting the activity of lysosome-bound mTOR.","[2.0, 1.0, 2.0]",Biology,train,1.6666666666666667,tweets,1002335662517948418
10.1016/j.cell.2018.04.038,Biology_tweet_81,Wow ! Another beautiful structure of telomerase. Recently there was a structure of human telomerase  ,"All telomerases contain a catalytic core of TERT and TER, which are sufficient to reconstitute activity in vitro.",Wow ! Another beautiful structure of telomerase. Recently there was a structure of human telomerase  ,"The cryo-EM structure of active Tetrahymena telomerase bound to telomeric DNA reveals unique insights into the catalytic core and DNA handling. All telomerases contain a catalytic core of TERT and TER, which are sufficient to reconstitute activity in vitro. The other seven proteins, p50, and two heterotrimeric replication protein A (RPA) related complexes, Teb1-Teb2/Rpa2-Teb3/Rpa3 (TEB) ) and p75-p45-p19 (Tetrahymena CTC1-STN1-TEN1 [CST]) , are paralogous to human proteins that only transiently associate with telomerase .","[5.0, 3.0, 4.0, 2.0, 2.0]",Biology,train,3.2,tweets,997209602478563329
10.1038/nn.3728,Biology_tweet_82,"Extinguishing fear: Active, phosphorylated FTY720 inhibits histone deacetylases &amp; facilitates fear extinction memory ","Altogether, these data indicate that FTY720 protected the SCID mice from deficits in expression of extinction in the contextual fear model.","Extinguishing fear: Active, phosphorylated FTY720 inhibits histone deacetylases &amp; facilitates fear extinction memory ","7d-f) , nor tonedependent fear conditioning that is hippocampus independent, nor did it affect extinction of response to the tone conditioned stimulus (Supplementary Fig. Altogether, these data indicate that FTY720 protected the SCID mice from deficits in expression of extinction in the contextual fear model. This aspect of learning is important for the organism to reduce fear-related behavior in response to a stimulus that no longer predicts an aversive event.","[2.0, 5.0, 3.0, 4.0, 4.0]",Biology,train,3.6,tweets,473715029712576512
10.1093/molbev/msv031,Biology_tweet_83,"Schizophrenia-associated loci enrich in genes near Human Accelerated Regions (HARs)
","Because the HAR-associated genes are enriched in neurodevelopmental processes and results below), one may argue that the enrichment we observed when using all the human genes as background might simply indicate that both schizophrenia genes and pHAR genes are brain related.","Schizophrenia-associated loci enrich in genes near Human Accelerated Regions (HARs)
","In addition, pHARs may not be conserved in nonprimate mammals or may be different between primates and other mammals. Because the HAR-associated genes are enriched in neurodevelopmental processes and results below), one may argue that the enrichment we observed when using all the human genes as background might simply indicate that both schizophrenia genes and pHAR genes are brain related. Both data sets yield the similar pattern of enrichment as when using all the autosomal genes as background ( fig.","[4.0, 3.0, 2.0]",Biology,train,3.0,tweets,569696064900628480
10.1016/j.cell.2018.07.032,Biology_tweet_86,"#Enterobactin, a #siderophore produced by E. coli and other bacteria, increases mitochondrial iron uptake in hosts, including humans. Fe(III)-Ent binds to the α subunit of the host mitochondrial ATP synthase. Enterobactin promoted growth in C. elegans.

","Given the symbiotic relationship between commensal E. coli and the host, one may speculate that an unknown beneficial mechanism has evolved in animals to use bacterial Ent for host iron homeostasis.","#Enterobactin, a #siderophore produced by E. coli and other bacteria, increases mitochondrial iron uptake in hosts, including humans. Fe(III)-Ent binds to the α subunit of the host mitochondrial ATP synthase. Enterobactin promoted growth in C. elegans.

","More importantly, this mechanism does not explain how host animals would cope with abundant Ent from non-infectious gut microbiota, of which enterobacteria are the most prevalent commensal microbes in both human and C. elegans . Given the symbiotic relationship between commensal E. coli and the host, one may speculate that an unknown beneficial mechanism has evolved in animals to use bacterial Ent for host iron homeostasis. In this study, by developing a unique and sensitive assay in C. elegans, we discovered an unexpected but logical role of bacterial Ent in supporting animal growth and iron level.","[2.0, 4.0, 1.0, 3.0]",Biology,train,2.5,tweets,1032645759340933120
10.1038/s41564-018-0276-6,Biology_tweet_87,Sorensen et al.: #Metagenomic analysis finds that higher soil temperatures are associated with smaller prokaryotic cell &amp; genome sizes:  ,"These results add evidence that supports selection for both smaller genomes and cells at higher temperatures, but also offer a key point of distinction.",Sorensen et al.: #Metagenomic analysis finds that higher soil temperatures are associated with smaller prokaryotic cell &amp; genome sizes:  ,"Surprisingly, it also suggests that microbial populations inhabiting complex environments, such as soils, may generally reflect similar overarching traits in genome size to those observed in laboratory studies. These results add evidence that supports selection for both smaller genomes and cells at higher temperatures, but also offer a key point of distinction. Although taxa that were enriched in hot soils characteristically had smaller genomes and cells, there is no evidence for contemporary genome streamlining in Centralia.","[4.0, 3.0, 1.0, 3.0, 5.0]",Biology,train,3.0,tweets,1059488344315437057
10.1098/rspb.2018.0761,Biology_tweet_88,"Interesting study on effects of #neonicotinoid exposure &amp; pollen diet on #bumblebee queen nest initiation in @username  Restricted diet impacts on queen &amp; colony overshadowed by insecticide exposure, but monofloral pollen diet reduced brood numbers ","Here, we demonstrate that sublethal exposure to imidacloprid, a widely used neonicotinoid-type insecticide, has a broad suite of negative effects on early-nesting bumblebee queens.","Interesting study on effects of #neonicotinoid exposure &amp; pollen diet on #bumblebee queen nest initiation in @username  Restricted diet impacts on queen &amp; colony overshadowed by insecticide exposure, but monofloral pollen diet reduced brood numbers ","Pollen diet was not an important driver of brood production overall, but among untreated queens, those fed monofloral Cistus pollen had significantly fewer larvae and pupae than queens fed mixed-source or monofloral Erica pollen ( p , 0.03 for counts of larvae and pupae). Here, we demonstrate that sublethal exposure to imidacloprid, a widely used neonicotinoid-type insecticide, has a broad suite of negative effects on early-nesting bumblebee queens. These effects were observed at the level of individual queens, who were less active and exhibited greater mortality when exposed to imidacloprid, but also at the colony level, where numbers of brood in the nest were dramatically reduced in treated queens, particularly when queens experienced sustained exposure to the insecticide.","[3.0, 5.0, 2.0, 5.0]",Biology,train,4.0,tweets,1006917387348668418
10.1038/s41467-019-09786-7,Biology_tweet_89,Epigenetic activation of the enhancer at IGF2 may enhance dopamine synthesis associated with major psychosis @username ,"In the striatum, inactivation of the Igf2 enhancer led to a decrease in TH protein levels and in dopamine (p < 0.05; one-way ANOVA; Fig.",Epigenetic activation of the enhancer at IGF2 may enhance dopamine synthesis associated with major psychosis @username ,"7c ), supporting dysregulation of the TH-IGF2 locus in major psychosis. In the striatum, inactivation of the Igf2 enhancer led to a decrease in TH protein levels and in dopamine (p < 0.05; one-way ANOVA; Fig. 3d , e); this effect was not observed in the frontal cortex ( Supplementary Fig.","[2.0, 3.0, 4.0, 4.0, 1.0]",Biology,train,2.8,tweets,1124255929543868418
10.1038/s41396-017-0042-4,Biology_tweet_9,"It's raining #viruses: ""each day some 800 million viruses cascade onto every square meter of the planet"", study published at the @username says. Also, viral deposition rates were 9 to 461 times greater than for #bacteria ","These deposition rates were 9-461 times greater than the rates for bacteria, which ranged from 0.3 × 10 7 to >8 × 10 7 m −2 per day.","It's raining #viruses: ""each day some 800 million viruses cascade onto every square meter of the planet"", study published at the @username says. Also, viral deposition rates were 9 to 461 times greater than for #bacteria ","Here, we demonstrate that even in pristine environments, above the atmospheric boundary layer, the downward flux of viruses ranged from 0.26 × 10 9 to >7 × 10 9 m −2 per day. These deposition rates were 9-461 times greater than the rates for bacteria, which ranged from 0.3 × 10 7 to >8 × 10 7 m −2 per day. The highest relative deposition rates for viruses were associated with atmospheric transport from marine rather than terrestrial sources.","[5.0, 4.0, 2.0, 4.0]",Biology,train,3.75,tweets,985210774120534016
10.1126/scitranslmed.aan1230,Biology_tweet_90,[Research Articles] TGF{beta} inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence  ,"In the mouse, this relationship was reversed upon inhibition of TGFR1, restoring a proportional regenerative response to liver injury, mimicking genetic deletion of p21.",[Research Articles] TGF{beta} inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence  ,"Therefore, severe liver injury in the mouse recapitulates the negative correlation between injury and regeneration observed in severe human disease (Fig. In the mouse, this relationship was reversed upon inhibition of TGFR1, restoring a proportional regenerative response to liver injury, mimicking genetic deletion of p21. Here, jaundice was once again improved and was associated with an inhibition of hepatocellular senescence (Fig.","[3.0, 4.0, 2.0, 3.0, 4.0]",Biology,train,3.2,tweets,1029792735497048064
10.1016/j.cell.2018.06.012,Biology_tweet_92,"Two action pathways in the brain: the ""direct' pathway controls individual elements in a sequence of actions, the ""indirect"" pathway controls whole subsquences - leading to hierarchical control of behavior  ","Importantly, the basal ganglia direct and indirect pathways interact distinctly with these different controllers.","Two action pathways in the brain: the ""direct' pathway controls individual elements in a sequence of actions, the ""indirect"" pathway controls whole subsquences - leading to hierarchical control of behavior  ","Together, these data suggest that the learned action sequence is likely organized in a hierarchical manner, with both local subsequence-level and global sequence-level controls. Importantly, the basal ganglia direct and indirect pathways interact distinctly with these different controllers. Similar to the observations in the LLRR sequence, brief stimulation (100 ms) of iSPNs after the first press of the LLLRRR sequence ablated the entire left subsequence, removing multiple upcoming left presses well beyond the stimulation period (Figures 5G and 5H) .","[4.0, 3.0, 2.0, 3.0, 4.0]",Biology,train,3.2,tweets,1012350063648133122
10.1111/j.1600-0706.2013.00620.x,Biology_tweet_93,MT @username: Climate change and annual survival in a temperate passerine (Long-tailed Tit)  (Oikos),"Using our model to estimate historical survival rates indicates that recent spring warming has led to an upward trend in survival rates, which has probably contributed to the observed long-term increase in the UK long-tailed tit population.",MT @username: Climate change and annual survival in a temperate passerine (Long-tailed Tit)  (Oikos),"There is little evidence for density dependence across the observed variation in population size. Using our model to estimate historical survival rates indicates that recent spring warming has led to an upward trend in survival rates, which has probably contributed to the observed long-term increase in the UK long-tailed tit population. Future climate change is predicted to further increase survival, under a broad range of carbon emissions scenarios and probabilistic climate change outcomes, even if precipitation increases substantially.","[2.0, 4.0, 5.0, 4.0]",Biology,train,3.75,tweets,446578033693319168
10.1073/pnas.1619294114,Biology_tweet_94,#Cbf { #beta } governs osteoblast-adipocyte #lineage #commitment through enhancing { #beta } #-catenin signaling an..,"Wnt/ β-catenin directs mesenchymal cell commitment to the osteogenic lineage and prevents adipogenic differentiation, resulting in increased new bone formation .",#Cbf { #beta } governs osteoblast-adipocyte #lineage #commitment through enhancing { #beta } #-catenin signaling an..,"Runx/Cbfβ Complex Promotes Wnt10b/β-Catenin Signaling and Inhibits c/ebpa Expression to Inhibit Lineage Switch into Adipocytes. Wnt/ β-catenin directs mesenchymal cell commitment to the osteogenic lineage and prevents adipogenic differentiation, resulting in increased new bone formation . Interestingly, Wnt10b is downregulated in Cbfβ-deficient cells and tissues, and ChIP plus promoter activity assay showed that Wnt10b is up-regulated by Cbfβ f/f Prx1-Cre calvarial cells cultured in osteogenic medium or osteogenic medium supplemented with Wnt3L conditional medium, normalized to hprt1.","[3.0, 2.0, 4.0]",Biology,train,3.0,tweets,907835255360548864
10.1139/cjz-2017-0071,Biology_easy_0,"""Very little is preventing their continued dispersal northward, provided they can survive winters,"" Walsh says.","2010) , suggest that very little is preventing their continued dispersal northward, provided they can survive winters.","""It was so exciting because it was further confirmation that this range expansion is still happening and that these animals are probably going to keep moving even further northward as the climate warms and as humans continue to alter the landscape with more agriculture and urbanization,"" Walsh says. ""Very little is preventing their continued dispersal northward, provided they can survive winters,"" Walsh says. ""This is a unique opportunity to study a documented, ongoing range expansion.","A lack of substantial landscape barriers for opossums , coupled with their nomadic behavior, illustrated by fathers and offspring discovered up to 33 km apart Beasley et al. 2010) , suggest that very little is preventing their continued dispersal northward, provided they can survive winters. Opossums collared with GPS units in Michigan had home ranges calculated between 10.9 and 200 hectares, depending on the equation used, with no difference between sexes .",[5],Biology,train,5.0,news,http://www.futurity.org/virginia-opossum-range-1684512/
10.1139/cjz-2017-0071,Biology_easy_1,Walsh and Tucker found that measurements of genetic diversity across 15 counties were best explained by days of snow on the ground.,"Using general linear models, we found that measurements of genetic diversity across fifteen counties are best explained by days of snow on the ground.","""More direct anthropogenic factors may also be important, including resources easily available in agricultural and suburban landscapes."" Walsh and Tucker found that measurements of genetic diversity across 15 counties were best explained by days of snow on the ground. Farm density was also found to be an important factor.","Two genetic clusters were identified: one on either side of Lake Michigan. Using general linear models, we found that measurements of genetic diversity across fifteen counties are best explained by days of snow on the ground. These models suggest opossum expansion may be facilitated by agricultural land development and at the same time be limited by their inability to forage in snow.",[5],Biology,train,5.0,news,http://www.futurity.org/virginia-opossum-range-1684512/
10.1038/s41467-018-07557-4,Biology_easy_4,"""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper.","In conclusion, this is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change.","The team found that 3.6 million people--three quarters of the current population in the Northern Hemisphere permafrost area--may be affected by infrastructure damage from permafrost thaw. ""This is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change,"" Hjort and his colleagues wrote in the paper. The most vulnerable areas identified in the paper are home to nearly one million people, and contain 36,000 buildings, 13,000 kilometers of roads, and 100 airports.","Our study can be considered to be a step forward toward these goals. In conclusion, this is the first study to explicitly show the amount of fundamental infrastructure potentially at risk across the Northern Hemisphere permafrost area under climate change. A total of 69% of the pan-Arctic residential, transportation, and Supplementary Table 3 .",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37952323296&p=1pl&v=1&x=YZkcSHKHdqhjfYYiUvZ_gw
10.1038/s41467-018-07557-4,Biology_easy_6,"Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached.""","Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached.","""Our results demonstrate that one-third of pan-Arctic infrastructure and 45 percent of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment. Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached."" He said there are different adaptations that can be made to reduce or prevent thaw--such as insulation--and potential thaw can be considered during the construction of new infrastructure.","Our results demonstrate that one-third of pan-Arctic infrastructure and 45% of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment. Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached. There is an urgent need for pan-Arctic geohazard mapping at high spatial resolution and an assessment of how changes in circumpolar permafrost conditions could affect infrastructure 14 .",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37952048427&p=1pl&v=1&x=WVBbJHZ_CDGkehwcKPFvdQ
10.1038/s41467-018-04906-1,Biology_easy_9,"""These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending.",These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending.,"If the user's temperature isn't within the required limits, the fingerprint authentication might not push through. ""These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending. This fingerprint sensor array has a high resolution with good transparency,"" the researchers said.",These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending. This fingerprint sensor array has a high resolution with good transparency. This sensor offers a capacitance variation~17 times better than the variation for the same sensor pattern using conventional ITO electrodes.,[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1038/s41598-017-11843-4,Biology_easy_12,Priority for new drug-development to efficiently treat TB must be focused on the discovery of novel therapeutic targets and approaches.,A priority for new drug-development to efficiently treat TB must be focused on the discovery of novel therapeutic targets and approaches.,"There is a new drug discovery that this study reported that said there is on track to generate new lead compounds along with their corresponding targets represent treat or need in the fight against TB. Priority for new drug-development to efficiently treat TB must be focused on the discovery of novel therapeutic targets and approaches. This study also found two groups of promising treatment but is still in the beginning stages (Ngmyen et al, 2017).","Above all, this work led to the identification of very promising anti-TB candidates that should be able to act against bacteria in various physiological stages, thus allowing a faster sterilization. A priority for new drug-development to efficiently treat TB must be focused on the discovery of novel therapeutic targets and approaches. This led to the selection of a set of promising CyC candidates that are devoid to cytotoxic properties towards host cells.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34850312293&p=1pl&v=1&x=Wz884h4s3tkDJfsmxreyRQ
10.1038/s41467-018-07557-4,Biology_easy_14,"""We show that nearly four million people and 70 percent of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost,"" the team wrote.",We show that nearly four million people and 70% of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost.,"Findings showed that the thawing permafrost will pose a significant threat to Arctic communities across the Northern Hemisphere by 2050. ""We show that nearly four million people and 70 percent of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost,"" the team wrote. ""Our results demonstrate that one-third of pan-Arctic infrastructure and 45 percent of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment.","We show that nearly four million people and 70% of current infrastructure in the permafrost domain are in areas with high potential for thaw of near-surface permafrost. Our results demonstrate that one-third of pan-Arctic infrastructure and 45% of the hydrocarbon extraction fields in the Russian Arctic are in regions where thaw-related ground instability can cause severe damage to the built environment. Alarmingly, these figures are not reduced substantially even if the climate change targets of the Paris Agreement are reached.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37952048427&p=1pl&v=1&x=WVBbJHZ_CDGkehwcKPFvdQ
10.1016/j.neuron.2017.06.028,Biology_easy_16,"We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","Hence, the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning, and memory associated with a repertoire of diseases.","These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories. When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London. We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","By simultaneously regulating the excitatory inputs and firing properties of PV+ cells, a perineuronal net protein drives PV+ interneuron wiring as well as network adaptation to experience. Hence, the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning, and memory associated with a repertoire of diseases. Consistently, pharmacological degradation of CSPGs in the adult reactivates cortical plasticity and enhances learning .",[5],Biology,train,5.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1186/s13578-015-0003-4,Biology_easy_19,"LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts.","LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H 2 S against I/R induced myocardial damage in the aging hearts.","Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts. LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H2S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H2S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3b pathway in the aging rat hearts.","Supply of NaHS not only increased PC-induced cardioprotection in the young hearts, but also lightened I/R induced-myocardial damage and significantly recovered the cardioprotective role of PC against I/R induced myocardial damage in the aging hearts. LY294002 (a PI3K inhibitor) abolished but N-acetyl-cysteine (NAC, an inhibitor of reactive oxygen species, ROS) further enhanced the protective role of H 2 S against I/R induced myocardial damage in the aging hearts. In conclusion, these results demonstrate that exogenous H 2 S recovers PC-induced cardioprotection via inhibition of oxidative stress and up-regulation of PI3K-Akt-GSK-3β pathway in the aging rat hearts.",[5],Biology,train,5.0,news,http://www.technology.org/2015/03/22/a-novel-target-for-the-treatment-of-aging-cardiovascular-diseases/
10.1038/s41467-018-08278-4,Biology_easy_22,"""These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation,"" conclude the researchers.","These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation, and that regenerative failure results from a deficiency of the wound environment that can be extrinsically manipulated to engineer regenerative events.","It's a fascinating area of science, and we're learning a lot from lab-grown organs about how the process might be triggered more naturally. If we are eventually to develop treatments to replace lost limbs, the BMP2 and BMP9 proteins may well have something to do with it. ""These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation,"" conclude the researchers.","In the case of BMP9 treatment, a coordinated response involving condensation and differentiation of chondrocytes coupled with the formation of a synovial cavity results in the regeneration of joint structures. These two regenerative responses identify discrete morphogenetic programs that can be activated either independently or coordinately within the context of the amputation wound. These findings provide further support for the view that cells of a non-regenerative mammalian amputation wound retain the positional information necessary to re-build structures removed by amputation, and that regenerative failure results from a deficiency of the wound environment that can be extrinsically manipulated to engineer regenerative events.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38466420113&p=1pl&v=1&x=IqxylWeo6-sJ6dtu0xtBJQ
10.1038/s41467-018-04906-1,Biology_easy_24,"This fingerprint sensor array has a high resolution with good transparency,"" the researchers said.",This fingerprint sensor array has a high resolution with good transparency.,"""These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending. This fingerprint sensor array has a high resolution with good transparency,"" the researchers said. ""Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display.""",These sensors exhibited excellent optoelectronic properties and outstanding reliability against mechanical bending. This fingerprint sensor array has a high resolution with good transparency. This sensor offers a capacitance variation~17 times better than the variation for the same sensor pattern using conventional ITO electrodes.,[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1139/cjz-2017-0071,Biology_easy_28,"""These models suggest opossum expansion may be facilitated by agricultural land development and at the same time may be limited by their inability to forage in snow,"" Walsh writes.",These models suggest opossum expansion may be facilitated by agricultural land development and at the same time be limited by their inability to forage in snow.,"Farm density was also found to be an important factor. ""These models suggest opossum expansion may be facilitated by agricultural land development and at the same time may be limited by their inability to forage in snow,"" Walsh writes. The presence of two distinct genetic clusters of this nomadic species--one on either side of Lake Michigan--suggests independent colonization of the two regions in the past.","Using general linear models, we found that measurements of genetic diversity across fifteen counties are best explained by days of snow on the ground. These models suggest opossum expansion may be facilitated by agricultural land development and at the same time be limited by their inability to forage in snow. In addition to the effects of climate change, contemporary range expansions may also be facilitated by human manipulation of the landscape and of populations.",[5],Biology,train,5.0,news,http://www.futurity.org/virginia-opossum-range-1684512/
10.1038/s41467-018-04627-5,Biology_easy_32,"For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said.","Over the course of the intervention, only the posterior CC retained a relationship to Reading Skill.","Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said. For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said. But the structure of this experiment underscores the importance of the findings, he added: Children participated in a tightly controlled, short-term educational intervention, with measurable, identifiable growth in brain tissue from start to finish.","Anatomy-behavior correlations depend on recent experience. Over the course of the intervention, only the posterior CC retained a relationship to Reading Skill. In contrast, as MD values declined in the AF and ILF, the instantaneous, cross-sectional correlation between reading and MD changed between sessions, as indicated by a significant interaction between MD and session in predicting Reading Skill for the intervention group (linear mixed effects model predicting Reading Skill from MD, session, and their interaction, with a random effect of subject, see Table 4 , there was no statistical difference in variance across sessions (indeed, variances were nearly matched; see also Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1016/j.cmet.2015.02.003,Biology_easy_33,Healthy legs boasted no discernible concentrations of the mineral.,"LPS boosted histone H3 lysine-4 trimethylation (H3K4me3) in the Nos2 gene (Figures S1D and S1E), indicating activation of Nos2 transcription .","Physicians found high concentrations of salt in the skin of patients' infected legs. Healthy legs boasted no discernible concentrations of the mineral. After treating the patients with antibiotics, the salt accumulation disappeared along with the infection.","Skin Na + concentrations (mean + SEM; n = 3). LPS boosted histone H3 lysine-4 trimethylation (H3K4me3) in the Nos2 gene (Figures S1D and S1E), indicating activation of Nos2 transcription . HS further augmented H3K4me3 at distinct regions in the Nos2 gene (Figures S1D and S1E).",[1],Biology,train,1.0,news,http://www.upi.com/Science_News/2015/03/03/Scientists-say-salt-may-guard-against-infection/4511425414509/
10.1038/s41467-018-05870-6,Biology_easy_36,"When they deleted Ago2 from the livers of mice, it was not toxic to the animals but it did stabilize energy metabolism.",While Ago2 protein levels were slightly decreased in the liver of mice fed HFD (Supplemental Fig.,"When they deleted Ago2 from the livers of mice, it was not toxic to the animals but it did stabilize energy metabolism. This helped stave off obesity and prevented the mice from developing diabetes and fatty liver disease, which can severely damage the vital organ--which helps rid the body of toxic substances. ""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology.","*p < 0.05, **p < 0.01 analysis revealed that hepatic Ago2 deficiency affected several functional clades such as glucose and lipid metabolism and protein translation regulation (Fig. While Ago2 protein levels were slightly decreased in the liver of mice fed HFD (Supplemental Fig. 6a ), several MD-miRNAs were highly induced in the liver of L-Ago2 WT mice fed HFD and a leptin-deficient (ob/ob) obese mice ( Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A
10.1016/j.cell.2015.07.058,Biology_easy_39,This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability.,"Thus, even in the absence of E1B-55K-induced MRN degradation, E4-ORF3 sequesters MRE11 and NBS1 in DE1B-55K-infected cells ( Figures 1C and S1A ).","MRN starts a domino effect, activating histones on surrounding chromosomes, which summons a cascade of additional proteins, resulting in a cell-wide, all-hands-on-deck alarm to help mend the DNA. This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability. Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea.","Consistent with this, MRE11 and RAD50 protein levels are decreased in WT and DE4-ORF3-virus-infected cells that express E1B-55K (Figure 1B) . Thus, even in the absence of E1B-55K-induced MRN degradation, E4-ORF3 sequesters MRE11 and NBS1 in DE1B-55K-infected cells ( Figures 1C and S1A ). However, DE1B-55K/DE4-ORF3 viruses do not degrade or mislocalize MRN and enable its role in viral replication to be determined (Figures 1B, 1C, and S1A) .",[1],Biology,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1016/j.cell.2018.06.045,Biology_easy_40,"""Our results are important for better understanding the infection-sensitivity of newborn babies and the risks of premature birth,"" says Dr Brodin.","Another possible explanation is that some other physiological process, shared by all children, triggers the stereotypic immune system development, but the changes seen implicate interactions with microbes.","The researchers were also able to show that the babies who had abnormal development of the gut flora during the first weeks also demonstrated a disorder of the immune system. ""Our results are important for better understanding the infection-sensitivity of newborn babies and the risks of premature birth,"" says Dr Brodin. ""What surprised us was how similar the changes were amongst babies,"" says Dr Brodin.","At the same time, gut microbiome composition differed between children, and the likelihood of shared exposures across such a diverse group of children seems unlikely. Another possible explanation is that some other physiological process, shared by all children, triggers the stereotypic immune system development, but the changes seen implicate interactions with microbes. These findings led us to hypothesize a possible model for stereotypic adaptive changes to diverse environmental exposures.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34897998946&p=1pl&v=1&x=xkojRQPNCvCSHFiL-aMHjA
10.1016/j.cmet.2015.02.003,Biology_easy_42,"""Our current study challenges this one-sided view and suggests that increasing salt accumulation at the site of infections might be an ancient strategy to ward off infections, long before antibiotics were invented.""",LPS-treated BMM from LysM Cre Nfat5 fl/fl mice showed reduced NFAT5 expression and NO production when exposed to salt-induced osmotic stress ( Figure S3 ).,"While too much salt may not be the best for your health, dietary salt could actually have some benefits. ""Our current study challenges this one-sided view and suggests that increasing salt accumulation at the site of infections might be an ancient strategy to ward off infections, long before antibiotics were invented."" The researchers noticed that there was an unusually high amount of sodium in the infected skin of mice that had been bitten by cage mates.","These findings suggest that HSD promotes salt storage in the skin and facilitates leishmanicidal activity by enhancing NOS2 expression, especially during resolution phase of infection. LPS-treated BMM from LysM Cre Nfat5 fl/fl mice showed reduced NFAT5 expression and NO production when exposed to salt-induced osmotic stress ( Figure S3 ). In vivo, myeloid-cell-specific Nfat5 deletion reduced the HSD-driven boost in NOS2 expression in lesional MF ( Figure 4D ).",[1],Biology,train,1.0,news,http://www.scienceworldreport.com/articles/22963/20150304/high-salt-diet-ward-infection-invading-microbes.htm
10.1016/j.cell.2015.07.058,Biology_easy_45,"""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes.","Similar to HU, KU-55933 prevents the phosphorylation of ATM, H2AX, RPA32, and KAP1 in WT-virus-infected cells (Figure 3B) .","""The requirement of MRN for sensing both cellular and viral genome breaks has profound consequences,"" says O'Shea. ""When MRN is recruited to cellular DNA breaks, it can no longer sense and respond to incoming viral genomes. O'Shea says this may explain why people with conditions resulting in high levels of cellular DNA damage (e.g., cancer, chemotherapy, inflammation and aging) are more susceptible to viral infections.","We conclude that global DDR signaling is activated downstream of viral DNA replication. Similar to HU, KU-55933 prevents the phosphorylation of ATM, H2AX, RPA32, and KAP1 in WT-virus-infected cells (Figure 3B) . HU and KU-55933 also prevent the phosphorylation of DNA-PKcs ( Figure 3B ), indicating that DNA-PK is activated downstream of ATM in response to virus DNA replication.",[1],Biology,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/ncomms4632,Biology_easy_46,Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power.,"By controlling the durations of the combined AC and DC E-fields in both the X and Y directions, the nanowires can be precisely manipulated in two dimensions along prescribed trajectories to the patterned magnetic bearings as shown in Fig.","The team's three-part nanomotor can rapidly mix and pump biochemicals and move through liquids, which is important for future applications. Fan and her team are the first to achieve the extremely difficult goal of designing a nanomotor with large driving power. With all its dimensions under 1 micrometer in size, the nanomotor could fit inside a human cell and is capable of rotating for 15 continuous hours at a speed of 18,000 RPMs, the speed of a motor in a jet airplane engine.","The magnetic attraction can be adjusted so precisely that it can anchor the nanowires to the bearings, but not too tightly to prevent the nanowires from rotating. By controlling the durations of the combined AC and DC E-fields in both the X and Y directions, the nanowires can be precisely manipulated in two dimensions along prescribed trajectories to the patterned magnetic bearings as shown in Fig. Once anchored on the nanobearing, the nanowire cannot be moved by the E-fields any more.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/05/140520123441.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2015.10.009,Biology_easy_47,"However, it was still able to cause septicemic and pneumonic plague,aEUR Rasmussen added.","However, our data suggest that Y. pestis did not fully adapt as a flea-borne mammalian pathogen until the beginning of the 1 st millennium BC, which precipitated the historically recorded plagues.","aEURoeThe Bronze Age plague represents an intermediate state where it had not yet evolved the capabilities to be transmitted by fleas or cause bubonic plague. However, it was still able to cause septicemic and pneumonic plague,aEUR Rasmussen added. The germ was spread mainly by such human-to-human contact until a genetic mutation allowed it to survive in fleasaEUR(tm) guts, choking their digestive tract and causing them to bite anything they can, wildly spreading plague.","In light of our findings, it is plausible that plague outbreaks could have facilitated-or have been facilitated by-these highly dynamic demographic events. However, our data suggest that Y. pestis did not fully adapt as a flea-borne mammalian pathogen until the beginning of the 1 st millennium BC, which precipitated the historically recorded plagues. and identified Y. pestis DNA sequences in 7 of the 101 individuals.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/black-death-germ-has-afflicted-humankind-longer-than-suspected/
10.1186/1471-2164-15-599,Biology_easy_48,This provides researchers with a new vision on human evolution.,"As shown here for humans, in bacteria, a correlation between species-specific protein evolutionary rate variation and positive selection signatures by the MK test was found .","This provides researchers with a new vision on human evolution. ""If a mutation or a change increases the chances of survival in the person carrying it, this mutation will tend to become prevalent in the population. The new protein will have changed its function compared to the ancestral protein.","Genes in the accelerated gene set showed remarkably high non-synonymous to synonymous substitutions; however, this alone was not sufficient to explain their high FI values, as deduced from the comparison with similarly rapidly evolving genes that were not human accelerated or with the set of rapidly evolving mammalianspecific genes. As shown here for humans, in bacteria, a correlation between species-specific protein evolutionary rate variation and positive selection signatures by the MK test was found . The impact of positive selection on the BS test selected genes, as determined by the observed FI and α values, was similar or even lower than that in the accelerated genes.",[1],Biology,train,1.0,news,http://www.healthcanal.com/genetics-birth-defects/53316-identified-almost-200-genes-that-have-evolved-more-rapidly-in-humans-than-in-other-primates.html
10.1038/nature12167,Biology_easy_49,"""This work highlights the need to modify how we classify the GPCR family,"" said TSRI Professor Raymond Stevens, PhD, the senior author on the study.","Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration .","However, the new work suggests that GPCRs may, in fact, be a subset of a larger group. ""This work highlights the need to modify how we classify the GPCR family,"" said TSRI Professor Raymond Stevens, PhD, the senior author on the study. ""The study suggests we should start calling the family 7-transmembrane receptors, which has been proposed by others before, to better reflect the diversity of the family, both structurally and in terms of function.""","The 7TM domains of SMO and FZD receptors are reminiscent of class A GPCRs 12 although their sequences are distinct from other GPCRs, sharing less than 10% sequence identity. Moreover, the SMO receptor can couple to G proteins, particularly G i , which inhibits cAMP production, controlling cell migration . 1 ) reveals a canonical GPCR 7TM bundle fold with a short helix VIII packed parallel to the membrane bilayer.",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/38297-scripps-research-institute-scientists-find-dissimilar-proteins-evolved-similar-7-part-shape.html
10.1186/s40168-015-0071-z,Biology_easy_50,The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota.,"As expected, glycan presence was not significantly different between samples with different major bifidobacterial species in Low-Bif qPCR stool, as bifidobacteria were not likely the major glycan consumer in samples where they were not abundant (data not shown).","The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors. The authors found that the intestinal tracts of infants fed by non-secretor mothers are delayed in establishing a bifidobacteria-dominated microbiota. The delay, the authors said, may be due to difficulties in the infant acquiring a species of bifidobacteria that is geared toward consuming the specific milk sugar delivered by the mother.","longum were of roughly equal abundance and, thus, were designated more generally as 'B. As expected, glycan presence was not significantly different between samples with different major bifidobacterial species in Low-Bif qPCR stool, as bifidobacteria were not likely the major glycan consumer in samples where they were not abundant (data not shown). In High-Bif qPCR stool, there were significant differences in the percentage of fucosylated species (ANOVA p = 0.0001) and the percentage of non-fucosylated neutral species (ANOVA p < 0.0001).",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.stemcr.2018.03.019,Biology_easy_51,"So the female iPS cells now have two active X chromosomes, while males have only one.","Interestingly, we found that within several of these cis-regulatory regions, changes in average methylation levels were already apparent in both SSEA1 subpopulations, and more pronounced in XaXa iPSCs (Figures 3D-3G) .","But when these cells are reprogrammed into iPS cells, the inactive X becomes active. So the female iPS cells now have two active X chromosomes, while males have only one. We now know that this explains the different behaviour of male and female cells after reprogramming because, over time, female cells lose one of the two X chromosomes and start behaving more or less like male iPS cells.""","Together, these results indicate that imprints are not only erased in XX iPSCs but also are not re-established upon global genome remethylation in XO iPSCs, which suggests that female iPSCs, regardless of the number of Xas, may have a similarly poor developmental potential as female ESCs . Interestingly, we found that within several of these cis-regulatory regions, changes in average methylation levels were already apparent in both SSEA1 subpopulations, and more pronounced in XaXa iPSCs (Figures 3D-3G) . Several conclusions arose from these analyses: first, we noticed a preferential loss of methylation within ESC-regulatory regions particularly for ESC superenhancers and OSN ESC binding sites in both SSEA1 + and SSEA1 À reprogramming intermediates ( Figure 3E ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33847856937&p=1pl&v=1&x=vV_Dne2GAjTKIkp14dSTOw
10.1038/s41467-019-09863-x,Biology_easy_52,"We still have a lot of work to do in figuring out the best way to curb climate change, but there is a clear consensus that the priciest option is to do nothing.",The version of JULES used here has an improved representation of physical and biogeochemical processes in the cold regions 80 .,"""Although between-country inequality has decreased over the past half century, there is ~90 percent likelihood that global warming has slowed that decrease,"" the authors said. Opposition to these plans is often based on the costs involved in implementing them, but these two new studies offer a powerful counterpoint to that argument. We still have a lot of work to do in figuring out the best way to curb climate change, but there is a clear consensus that the priciest option is to do nothing.","The simulated CO 2 and methane fluxes from thawing permafrost as a function of time represent the strength and timing of the PCF. The version of JULES used here has an improved representation of physical and biogeochemical processes in the cold regions 80 . C max is a limit on the maximum possible cumulative emissions determined by the initial carbon stock estimates in SiBCASA (560 GtC) and JULES (738 GtC); ω (GtC K −1 ) is equilibrium sensitivity of the carbon emissions to permafrost warming; τ (yr) is the time lag at t = 0 (pre-industrial) corresponding to the given C max ; p is a fixed power that defines the dynamics of how the equilibrium is approached; φ ω (Equation 3), φ τ and φ p (Equation 2) are temperature-driven corrections to the parameters ω,τ,p.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39063152220&p=1pl&v=1&x=rfZKa3AOnuRs3Dq6otYxhw
10.1016/j.cell.2018.04.038,Biology_easy_53,"advertisement

This is the first time researchers have seen telomerase in the process of making DNA.","While the TRE-template-TBE play direct regulatory roles in sstDNA synthesis, other elements of TER in the catalytic core function in assembly, as structural scaffolds or as linkers.","Many mutations that scientists attributed to the TEN region in fact disrupt TEN's interaction with TRAP, the researchers report in Cell. advertisement

This is the first time researchers have seen telomerase in the process of making DNA. This new research brings this goal closer to reality by providing clues about what parts to target.","Differences observed in the DNA-free and DNA-bound telomerase density maps indicate that the TRAP-TRE L interaction stabilizes and/or extends the TRAP-TEN interface ( Figures S3E and S3F ). While the TRE-template-TBE play direct regulatory roles in sstDNA synthesis, other elements of TER in the catalytic core function in assembly, as structural scaffolds or as linkers. The main interactions between the pseudoknot and the CTE are at A 80 U 81 that form base triples and residues at the pseudoknot-TRE junction ( Figure 4G ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1373/clinchem.2012.187617,Biology_easy_55,This is actually through our microbiome's connection to the immune system.,SCFAs may function as microbe-derived signals that influence carbohydrate metabolism and gut physiology by stimulating mammalian peptide secretion and serving as energy sources for gut epithelial cells.,These little guys play a huge role in regulating our health and make it possible for us to live in the way we're used to. This is actually through our microbiome's connection to the immune system. They aren't hurting us as long as they stay under control.,"SCFAs such as propionate can be used for de novo glucose or lipid synthesis and serve as an energy source for the host. SCFAs may function as microbe-derived signals that influence carbohydrate metabolism and gut physiology by stimulating mammalian peptide secretion and serving as energy sources for gut epithelial cells. By stimulating GLP-1 secretion, bacterial SCFAs provide signals that suppress glucagon secretion, induce glucose-dependent insulin secretion, and promote glucose homeostasis.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=40253496747&p=1pl&v=1&x=Ul5zHhtDyat4L2c3FwEaew
10.1098/rsos.171474,Biology_easy_56,"""They might think Fortnite is violent or that people who play Mario are more likely to be aggressive towards turtles.","Finally, in this study, we draw general inferences about gaming effects in a general way across the population as a whole.","He found that people who have never played video games before are more likely to have biases about them and unrealistic expectations about them. ""They might think Fortnite is violent or that people who play Mario are more likely to be aggressive towards turtles. But once you get the hands-on experience, you see that this is a pretty silly idea.""","To this end, field or natural experiments using multi-wave random-intercepts cross-lagged panel modelling should follow the present work to provide an expanded test of the effects of violent gaming on human behaviour. Finally, in this study, we draw general inferences about gaming effects in a general way across the population as a whole. It might be the case that specific cohorts of people sharing background factors associated with technology use such as carer educational attainment or material deprivations are more or less likely to be influenced by their experiences with virtual environments .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39882021759&p=1pl&v=1&x=WDSVA9_GGY2tcF2kX9kO8w
10.1016/j.mito.2018.08.001,Biology_easy_57,"""Once the triggers of a chronic injury have been identified and removed, and on-going symptoms treated, we need to think about fixing the underlying issue of impaired healing.",The good news is that the dauer state in the worm model is completely reversible.,"When the cast is removed, the limb is weak, but over time, muscles recover and bone that was once broken may actually be stronger."" ""Once the triggers of a chronic injury have been identified and removed, and on-going symptoms treated, we need to think about fixing the underlying issue of impaired healing. By shifting the focus away from the initial causes to the metabolic factors and signaling pathways that maintain chronic illness, we can find new ways to not only end chronic illness but prevent it.""","Overall, the dauer state and other hypometabolic states permit survival under harsh conditions, but at a high price of much-altered and much-restricted normal function. The good news is that the dauer state in the worm model is completely reversible. If dauer is a good model for ME/CFS, then there is hope that by studying the molecular controls of the dauer phenotype, new treatments might be discovered rationally to help stimulate the exit from the dauer-like state and begin the process of recovery.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37036494336&p=1pl&v=1&x=fSLbjdg9pAN1rFXsEu2RGA
10.1038/s41467-019-09863-x,Biology_easy_59,"Even if action is taken to limit warming to 1.5degC by the end of the century, the research found melting permafrost would still add $24.8 trillion to overall climate costs.","Compared with zero PCF and constant SAF, which are the legacy values that have been used in climate policy modelling to date, the combined nonlinear PCF and SAF cause statistically significant extra warming globally under the low and medium emissions scenarios.","Even if action is taken to limit warming to 1.5degC by the end of the century, the research found melting permafrost would still add $24.8 trillion to overall climate costs. In an interview with the Guardian, Yumashev called his study's results ""disheartening,"" but said nations of the world have the technological capacity to confront the crisis. What's needed, he said, is urgency and political will.","The PCF also develops state-dependent lagged behaviour. Compared with zero PCF and constant SAF, which are the legacy values that have been used in climate policy modelling to date, the combined nonlinear PCF and SAF cause statistically significant extra warming globally under the low and medium emissions scenarios. For high emissions scenarios, the strength of the PCF saturates, and the weakening SAF gradually cancels the warming effect of the PCF; for BaU, this takes place from the second half of the 22nd century onwards.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1016/j.neuron.2017.06.028,Biology_easy_60,"When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London.","Specifically, expression of the GPI-anchored isoform of BCAN by PV+ cells is responsible for regulating the density of their excitatory synapses.","These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories. When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London. We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","In this study, we have shown that PV+ interneurons expressing BCAN receive more glutamatergic inputs than similar cells lacking BCAN. Specifically, expression of the GPI-anchored isoform of BCAN by PV+ cells is responsible for regulating the density of their excitatory synapses. In addition, release of BCAN2 from astrocytes may also contribute to synapse maturation onto PV+ cells.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1016/j.cell.2015.07.058,Biology_easy_62,The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell.,"Furthermore, capsid protein expression and total virus titers are similar in WT-virusinfected cells treated with DMSO, or AZ20 (Figures S3F and S3G) .","When it comes to defending against DNA viruses, however, the Salk team found something interesting: the cell's response system begins the same way (with MRN detecting either DNA or viral breaks) but never progresses to the global alarm signal in the case of the virus. The cell detects the unauthorized replication and the MRN complex grabs and selectively neutralizes viral DNA without triggering a global response that would arrest or kill the cell. The MRN response to the virus stays localized and only selectively prevents viral, but not cellular, replication.","KU-55933 has no impact on WT virus genome replication levels ( Figure 3H ). Furthermore, capsid protein expression and total virus titers are similar in WT-virusinfected cells treated with DMSO, or AZ20 (Figures S3F and S3G) . ATM inhibition also does not impact the cytopathic effect associated with WT virus replication (data not shown).",[1],Biology,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1126/sciadv.1700581,Biology_easy_64,"""This brings on a compound effect and increases the overall drought impact significantly.",These impacts are especially worth considering for the 278 transboundary waterways (37) associated with shared watersheds occupying nearly half of the world's land .,"""Most importantly, our findings also showed a steep rise in the simultaneous occurrence of multiple drought types,"" said lead author Deepthi Rajsekhar, a former postdoctoral scholar in Gorelick's lab now working at the California Department of Water Resources. ""This brings on a compound effect and increases the overall drought impact significantly. In a sad twist, an end to the Syrian civil war could add to Jordan's water misery.",Water security assessments spanning future decades would greatly benefit from reflecting on the joint impacts of multiple drought types and humaninduced land-use change. These impacts are especially worth considering for the 278 transboundary waterways (37) associated with shared watersheds occupying nearly half of the world's land . Future water security concerns are critical in arid countries reliant on transboundary freshwater resources and where the combined effects of future droughts and humaninduced land-use changes are likely to continue.,[1],Biology,train,1.0,news,https://www.sciencedaily.com/releases/2017/08/170830202128.htm
10.1073/pnas.1511220112,Biology_easy_65,The researchers' next step will be to analyze variability in the shoulder blade of modern humans and the genetic sequences that cause those differences to understand how these factors influence the likelihood to get rotator cuff injuries.,"This final shift toward a fully lateralized spine and glenoid was likely costly to climbing efficiency and/or arm hanging , while also increasing shear stress at the shoulder and elevating the risk of rotator cuff injury .","""For a baseball pitcher, depending on your shoulder shape, you might want to emphasize some strengthening exercises over others to protect your rotator cuff."" The researchers' next step will be to analyze variability in the shoulder blade of modern humans and the genetic sequences that cause those differences to understand how these factors influence the likelihood to get rotator cuff injuries. ""With that information, we hope that one day doctors can diagnose and help prevent shoulder injuries years before they happen, simply by rubbing a cotton swab on a patient's cheek to collect their DNA"".","Interestingly, the later A. sediba has a more human-like shoulder compared with earlier A. afarensis, suggesting that the ancestor of A. sediba and Homo shared the more derived configuration. This final shift toward a fully lateralized spine and glenoid was likely costly to climbing efficiency and/or arm hanging , while also increasing shear stress at the shoulder and elevating the risk of rotator cuff injury . Given the fitness value of efficient climbing for accessing food and avoiding predators, we speculate that the selective forces driving this shift must also have been significant.",[1],Biology,train,1.0,news,http://www.technology.org/2015/09/09/shouldering-burden-evolution/
10.1080/10635150701775111,Biology_easy_66,"In all three cases, the data was limited, especially in the case of the ecological niche modeling.","However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself.","He admits three specimens was not a lot, but ""the whole genome data of one passenger pigeon carries the information of the whole species."" In all three cases, the data was limited, especially in the case of the ecological niche modeling. Yet, Chih-Ming is confident.","Our preliminary analysis based on 12S mtDNA (not shown) finds the Zanzibar specimen falling in a clade with P. ravenala and the other Comoros specimens forming a polytomy with P. dubia from Northwest Madagascar. However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself. Nevertheless, based on the findings of this study, we anticipate that this new application of ecological niche modeling will greatly facilitate species delimitation, and thus also aid the recognition of both additional species diversity and more recent speciation events.",[1],Biology,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1038/s41467-018-05229-x,Biology_easy_67,"In a bulk solid, Wannier-Stark localization can only be maintained for an extremely short period of time, shorter than a single oscillation of infrared light.","In the high-field regime, wave functions (gray) are confined to a small number of lattice sites.","""This fundamental effect was predicted more than 80 years ago. In a bulk solid, Wannier-Stark localization can only be maintained for an extremely short period of time, shorter than a single oscillation of infrared light. Using the ultrafast laser systems at the University of Konstanz, Wannier-Stark localization has now been demonstrated for the first time.","Airy-type envelope wave functions extending over many lattice sites lead to finite transition probabilities for energies below the unbiased bandgap energy E gap (red arrow) and oscillating absorption changes in the interband continuum above E gap (orange arrow). In the high-field regime, wave functions (gray) are confined to a small number of lattice sites. This leads to discrete transition energies for electrons within the same site (orange arrow, n = 0) and between different sites (red and blue arrows, n = ± 1) which are separated by the Bloch energy ΔE = ħΩ B .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1098/rsos.180695,Biology_easy_68,"Interestingly, citizen scientists in Alaska also reported indoor conditions most similar to those in Namibia.",This literature suggests that the many ways in which the climate people prefer for their homes might be modulated and why.,"For example, citizens in North Carolina reported indoor conditions most like those in Namibia, which is in southern Africa and south of the equator. Interestingly, citizen scientists in Alaska also reported indoor conditions most similar to those in Namibia. ""Only three states reported indoor conditions that were most similar to non-African outdoor conditions.","Thermal comfort can be influenced by culture , by wind speed and humidity [27 -30] and mean radiant temperature . This literature suggests that the many ways in which the climate people prefer for their homes might be modulated and why. But what these do not change is the reality that thermal comfort itself, evolved.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38804472041&p=1pl&v=1&x=HgOgei0b1kV3BVEuJ5LhBA
10.1038/s41396-017-0042-4,Biology_easy_69,"So essentially ... none of these microbes statistically speaking would infect humans, so it's not something we have to worry about.""","These deposition rates were 9-461 times greater than the rates for bacteria, which ranged from 0.3 × 10 7 to >8 × 10 7 m −2 per day.","However, the rain was less efficient removing viruses from the atmosphere,"" said author and microbial ecologist Isabel Reche from the University of Granada

It may sound like something out of a science fiction movie, but it's not quite so perilous. Suttle explains that early all of the viruses circulating and dropping from the Earth's atmosphere actually help regulate ecosystems across the planet. So essentially ... none of these microbes statistically speaking would infect humans, so it's not something we have to worry about.""","Here, we demonstrate that even in pristine environments, above the atmospheric boundary layer, the downward flux of viruses ranged from 0.26 × 10 9 to >7 × 10 9 m −2 per day. These deposition rates were 9-461 times greater than the rates for bacteria, which ranged from 0.3 × 10 7 to >8 × 10 7 m −2 per day. The highest relative deposition rates for viruses were associated with atmospheric transport from marine rather than terrestrial sources.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33888158467&p=1pl&v=1&x=tFCRvwLCRGyes3rifRfszA
10.2337/db13-1600,Biology_easy_71,"""The more tightly doctors try to control patients' blood glucose, the more episodes of hypoglycemia the patients experience.","Decreasing the responsiveness of these neurons to any single molecule might, in turn, allow them to respond or integrate a variety of incoming signals to help achieve the appropriate motor response.","The end result, Donovan said, is a vicious cycle. ""The more tightly doctors try to control patients' blood glucose, the more episodes of hypoglycemia the patients experience. And the more episodes they experience, the less ability they have to counter-regulate or combat the onset of hypoglycemia and so these people become increasingly prone to becoming hypoglycemic.""","Perhaps CNS glucose sensors are insensitive to slow or small glycemic changes, thereby serving as a ""fail safe"" mechanism for catastrophic declines in glucose. Decreasing the responsiveness of these neurons to any single molecule might, in turn, allow them to respond or integrate a variety of incoming signals to help achieve the appropriate motor response. As such, their role in glycemic detection may be secondary to other homeostatic parameters, e.g., energy expenditure.",[1],Biology,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1016/j.compag.2016.07.028,Biology_easy_72,"Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency.","Advancement in plant phenomics would enable more effective utilization of genetic data, and ultimately lead to novel gene discovery and improved crop yield and quality in the field.","Second sight

Ge and Schnable also showed that conventional RGB imagery from the phenotyping system can be used to estimate the daily growth of corn plants - and how efficiently they use water to stimulate that growth - during their first few weeks of development. Ge and Schnable found that the software's estimates of plant size correlated strongly with their own measurements of plant weight, leaf area and water use efficiency. The methods required to establish those baseline values help illustrate why the RGB and hyperspectral imaging techniques should prove so useful, the researchers said.","It would fill the gap between the low cost of generating large scale datasets of plant genotypes and the time consuming and expensive process of collecting large scale plant phenotypic datasets. Advancement in plant phenomics would enable more effective utilization of genetic data, and ultimately lead to novel gene discovery and improved crop yield and quality in the field. Phenotypic data collected from plants grown in the field is arguably the most informative for guiding plant breeding efforts .",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1073/pnas.1414221111,Biology_easy_75,After 48 hours the parasite was undetectable.,These morphological changes reach a maximum by 7-8 h after treatment.,"In a mouse model of malaria, a single dose of (+)-SJ733 killed 80 percent of malaria parasites within 24 hours. After 48 hours the parasite was undetectable. Planning has begun for safety trials of the compound in healthy adults.","This immediate response triggers other cellular responses, probably including the arrest of protein synthesis , and these are integrated at the level of both the parasite (manifested as a swollen, development-arrested phenotype) and the host erythrocyte (manifested as induction of an eryptotic/senescent phenotype). These morphological changes reach a maximum by 7-8 h after treatment. In vivo, these effects trigger rapid clearance of the infected, treated erythrocytes through host-mediated mechanisms used to clear aging red cells.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1038/s41396-017-0042-4,Biology_easy_76,Suttle explains that early all of the viruses circulating and dropping from the Earth's atmosphere actually help regulate ecosystems across the planet.,"Samples that were predominantly marine in origin are shown as blue circles, and samples with predominantly Saharan in origin are shown as orange circles transformed) were positively correlated with this larger size fraction of organic aerosol (n = 36, r = 0.38, p < 0.05) (Fig.","However, the rain was less efficient removing viruses from the atmosphere,"" said author and microbial ecologist Isabel Reche from the University of Granada

It may sound like something out of a science fiction movie, but it's not quite so perilous. Suttle explains that early all of the viruses circulating and dropping from the Earth's atmosphere actually help regulate ecosystems across the planet. So essentially ... none of these microbes statistically speaking would infect humans, so it's not something we have to worry about.""","Virus deposition rates were significantly correlated to the organic fraction of aerosols smaller than 0.7 μm (n = 32, r = 0.62, p < 0.01), whereas bacteria deposition rates were significantly correlated to the organic fraction of aerosols with a size >0.7 μm (n = 36, r = 0.38, p < 0.05). Samples that were predominantly marine in origin are shown as blue circles, and samples with predominantly Saharan in origin are shown as orange circles transformed) were positively correlated with this larger size fraction of organic aerosol (n = 36, r = 0.38, p < 0.05) (Fig. 4b) , but there was no significant correlation with virus deposition rates (n = 33, r = 0.33, p = 0.063; Supplementary Figure S1 ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33888158467&p=1pl&v=1&x=tFCRvwLCRGyes3rifRfszA
10.1073/pnas.1601081113,Biology_easy_77,"(Photo : Frank Vassen/Wikimedia Commons)

Apart from being adorably cute, mouse lemurs' DNA could hold the key in revealing the mysterious past of the island nation of Madagascar.",Phylogeographic analysis can be described as the study of the geological and climatological processes that have produced contemporary geographic distributions of populations and species.,"(Photo : Frank Vassen/Wikimedia Commons)

Apart from being adorably cute, mouse lemurs' DNA could hold the key in revealing the mysterious past of the island nation of Madagascar. But this study reveals that the answer to this bugging mystery is embedded in the tiny lemurs roaming in the island nation. Yoder and her team also discovered genetic similarities between mouse lemurs and other species that live apart from each other.","By examining patterns of both inter-and intraspecific genetic diversity in mouse lemur species found in the eastern, western, and Central Highland zones, we conclude that the natural environment of the Central Highlands would have been mosaic, consisting of a matrix of wooded savanna that formed a transitional zone between the extremes of humid eastern and dry western forest types. Phylogeographic analysis can be described as the study of the geological and climatological processes that have produced contemporary geographic distributions of populations and species. Phylogenetic and population genetic patterns in a five-species clade of mouse lemurs suggest that longitudinal dispersal across the island was readily achieved throughout the Pleistocene, apparently ending at ∼55 ka.",[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/25503/20160719/cute-mouse-lemurs-solve-mystery-madagascar-past.htm
10.1016/j.molcel.2014.05.030,Biology_easy_79,"""If you tend to burn, then you may have inherited a problem with your MC1R, and you probably should avoid purposeful UV exposure like tanning bed use or unprotected sun exposure.""","We found that cAMP signaling influenced kinetics of XPA nuclear accumulation and recruitment to chromatin after UV-induced DNA damage (Figures 2A, 2B and 2C) .","""If you tan well, then your MC1R probably works well,"" D'Orazio said. ""If you tend to burn, then you may have inherited a problem with your MC1R, and you probably should avoid purposeful UV exposure like tanning bed use or unprotected sun exposure."" D'Orazio and his research team found an important molecular link between MC1R signaling and DNA repair in their study.","cAMP stimulation failed to increase total protein levels of core NER factors ( Figure S3A ), however we explored whether distribution of key NER proteins to sites of UV-induced DNA damage might be affected. We found that cAMP signaling influenced kinetics of XPA nuclear accumulation and recruitment to chromatin after UV-induced DNA damage (Figures 2A, 2B and 2C) . and S3E), whereas addition of ASIP, a potent MC1R antagonist that down-regulates cAMP signaling, abrogated MSH-mediated benefit, confirming the importance of XPA and MC1R in the repair of UVinduced DNA damage.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/07/140715141753.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41568-018-0020-9,Biology_easy_80,"We look forward to results from the myelofibrosis study, as well as the ongoing studies of PU-H71 in breast cancer and PU-AD in Alzheimer's disease.","Ultimately, then, classical approaches to drug discovery are inappropriate when one targets the chaperome.","""New science emerging from Samus and the Chiosis group has led to a greater understanding of the role the epichaperome plays in cancer and Alzheimer's disease, as well as our ability to disrupt a biologic mechanism fundamental to these diseases,"" said Barbara Wallner, Ph.D., Chief Scientific Officer of Samus Therapeutics. ""PU-H71 and PU-AD inhibit with high specificity the epichaperome complex in diseased cells and thereby mitigate the adverse effects of disease enhancing proteins without affecting normal cells. We look forward to results from the myelofibrosis study, as well as the ongoing studies of PU-H71 in breast cancer and PU-AD in Alzheimer's disease.","This realization has implications for the development of chaperome inhibitors and emphasizes the importance of considering factors such as the residence time, pharmacokinetics (PKs) and pharmacodynamics (PDs) to fully appreciate the distinctions between HSP90 agents 145 (Box 4). Ultimately, then, classical approaches to drug discovery are inappropriate when one targets the chaperome. Instead, attention must be paid during drug development to the ability of the compound to modulate relevant, disease-specific chaperome species.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34294149057&p=1pl&v=1&x=pzihluZRVcZJ0XNPGmH0Mw
10.1016/j.cell.2016.04.014,Biology_easy_81,"""We are the first ones to locate the variations in the landscape of innate lymphoid cell regulation.","In contrast to mice, which express Il17 in both Th17s and a subset of ILC3s, humans express these cytokines only in Th17s (Figure 1E) .","This observation could pave the way to more personalized treatments for autoimmune diseases, the researchers said. ""We are the first ones to locate the variations in the landscape of innate lymphoid cell regulation. Now that we know where the master switches are, we can see that those variants are associated with autoimmune disease because they affect the regulation of these immune cells.""","We also identified an SE in Th17 cells that spanned its signature IL17A/IL17F cytokine locus, as well as the neighboring MCM3 gene, which is expressed in all cell types ( Figure 5C ). In contrast to mice, which express Il17 in both Th17s and a subset of ILC3s, humans express these cytokines only in Th17s (Figure 1E) . Only a subset of enhancers active in Th17s were in regions of high sequence conservation, perhaps reflecting evolutionary revisions to the regulatory landscape of this locus that endow Th17-specific expression in humans.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/scientists-discover-master-dimmer-switches-that-control-activity-of-immune-cells/
10.1038/s41467-018-04627-5,Biology_easy_84,"Teachers have the potential to develop their students' brains, regardless of whether they have the resources to provide individualized instruction for each student in their class.","61 , it remains possible that a sufficiently intense math intervention might prompt changes not only within the left arcuate but also within many of the same tracts identified here.","Yeatman believes the findings can extend to schools. Teachers have the potential to develop their students' brains, regardless of whether they have the resources to provide individualized instruction for each student in their class. ""While many parents and teachers might worry that dyslexia is permanent, reflecting intrinsic deficits in the brain, these findings demonstrate that targeted, intensive reading programs not only lead to substantial improvements in reading skills, but also change the underlying wiring of the brain's reading circuitry,"" Yeatman said.","Despite the lack of a group-level intervention effect in the left arcuate in ref. 61 , it remains possible that a sufficiently intense math intervention might prompt changes not only within the left arcuate but also within many of the same tracts identified here. Indeed, our effects may reflect the intensity and quality of the learning environment, rather than the specific trained skills.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1186/s40168-015-0071-z,Biology_easy_85,"Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of her infant's gut microbiota.","More surveys of the absolute abundance of infant bifidobacteria in developing and undeveloped areas of the world are needed, along with the measurement of relevant exposure-related metadata.","The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of her infant's gut microbiota. It also reveals clues for enriching desirable bacteria in populations at risk of intestinal diseases -- such as preemies.","As modern hygiene standards and other cultural practices may lead to a reduction in the exposure levels to different bifidobacterial species, the phenomenon of the low bifidobacteria infant might be an artefact of developed countries. More surveys of the absolute abundance of infant bifidobacteria in developing and undeveloped areas of the world are needed, along with the measurement of relevant exposure-related metadata. In conclusion, our work reveals important functional differences in the microbiota of infants fed by mothers of differing secretor.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04627-5,Biology_easy_86,"""In reality, different experiences can shape the brain in dramatic ways throughout development.""","However, the effects of intervention are not limited to these regions.","""We were able to detect changes in brain connections within just a few weeks of beginning the intervention program. ""In reality, different experiences can shape the brain in dramatic ways throughout development."" After eight weeks of intensive instruction among study participants who struggled with reading, two of those three areas showed evidence of structural changes -- a greater density of white matter and more organized ""wiring.""","Intensive reading training causes rapid changes in tissue properties within the left AF and ILF, two tracts considered crucial for skilled reading. However, the effects of intervention are not limited to these regions. Instead, we find widespread change throughout multiple cortical association and projection tracts.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1098/rsbl.2014.0993,Biology_easy_87,"Only at full moon do the insects have a moon to navigate by during the entire night.""",To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations .,"""We think it is all about maximizing the efficiency, not only regarding the preciseness of pollinator navigation and attraction to the cones, but also in terms of number of efficient dark hours. Only at full moon do the insects have a moon to navigate by during the entire night."" Likewise, an investigation into the insect species might help shore up the findings.","The full moon is thus important for efficient pollination of E. foeminea both for pollinator navigation in the dark and for attraction to the cones. To experimentally remove the forces of celestial gravitation is difficult but our hypothesis could be further tested by experiments on moonlight detection in plants and by continuing to make predictions followed by targeted observations . By contrast, we find no correlation between the phases of the moon and secretion of pollination drops in the sympatric but wind-pollinated E. distachya ( figure 2b) ).",[1],Biology,train,1.0,news,http://news.sciencemag.org/biology/2015/04/plant-releases-its-pollen-full-moon
10.1038/s41467-018-05709-0,Biology_easy_89,The same itch-suppressant effect was also observed in tests with dogs carried out by the researchers in cooperation with the University of Zurich's Veterinary Department.,7 TPA023B reduces acute itch mainly through spinal α2GABA A Rs.,"Mice that were administered with the drug scratched themselves less often, and their skin changes healed significantly quicker than in animals that were given a placebo. The same itch-suppressant effect was also observed in tests with dogs carried out by the researchers in cooperation with the University of Zurich's Veterinary Department. Moreover, the drug did not cause obvious undesired side effects.","Given the 7 TPA023B reduces acute itch mainly through spinal α2GABA A Rs. P = 0.004, unpaired two-sided t-test, n = 7 and 6, for vehicle and TPA023B.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34818663460&p=1pl&v=1&x=L-gib_N5MhiGEP62jfuz-g
10.1038/s41467-019-09863-x,Biology_easy_90,"Opposition to these plans is often based on the costs involved in implementing them, but these two new studies offer a powerful counterpoint to that argument.","It is possible that with an explicit modelling of the other climatic and societal tipping elements, as well as with comprehensive representation of the impacts of rising temperatures and increasing extreme weather events on economic growth 63 , both the economic effect of climate change with legacy Arctic feedbacks, and the additional impacts due to the nonlinear PCF and SAF, would be higher compared to those reported here.","""Although between-country inequality has decreased over the past half century, there is ~90 percent likelihood that global warming has slowed that decrease,"" the authors said. Opposition to these plans is often based on the costs involved in implementing them, but these two new studies offer a powerful counterpoint to that argument. We still have a lot of work to do in figuring out the best way to curb climate change, but there is a clear consensus that the priciest option is to do nothing.","5a ; even with the current parameterisations, the upper tails in the distributions are at their lowest for the 1.5°C scenario. It is possible that with an explicit modelling of the other climatic and societal tipping elements, as well as with comprehensive representation of the impacts of rising temperatures and increasing extreme weather events on economic growth 63 , both the economic effect of climate change with legacy Arctic feedbacks, and the additional impacts due to the nonlinear PCF and SAF, would be higher compared to those reported here. The associated global risks are minimised at lower emissions.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39063152220&p=1pl&v=1&x=rfZKa3AOnuRs3Dq6otYxhw
10.1186/s40168-015-0071-z,Biology_easy_91,"The relationship between human genetics, breast milk and Bifidobacterium appears to have developed throughout mammalian evolution.",Figure 7 shows that stool samples with Low-Bif qPCR counts (N = 43) and those with High-Bif qPCR counts (N = 62) were from infants that received matching milk samples of mostly comparable glycan composition.,"""What this work does show us is that the mother's genotype matters, and that it influences the breast milk, which clearly drives the establishment of microbes in the intestines of their babies."" The relationship between human genetics, breast milk and Bifidobacterium appears to have developed throughout mammalian evolution. The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors.","A Fisher's exact test yielded p = 0.015, suggesting the probability that bifidobacteria levels will be HighBif qPCR is greater for infants who are receiving milk from secretor mothers. Figure 7 shows that stool samples with Low-Bif qPCR counts (N = 43) and those with High-Bif qPCR counts (N = 62) were from infants that received matching milk samples of mostly comparable glycan composition. On average the milk received by Low-Bif qPCR infants was significantly higher in α(1-3/4)-fucosylated oligosaccharides than milk received by the High-Bif qPCR infants (14.2% ± 9.2% versus 10.1 ± 7.9%, respectively; p = 0.021), but this may be mostly due to the trade-off between 2′-and 3′-fucosylation related to secretor status, which was shown above to correlate with an increase in bifidobacterial Figure 2 Comparison of relative levels of gut microbiota in secretor-fed infants and non-secretor-fed infants.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cub.2007.01.061,Biology_easy_92,"Until we examine uncertainty at the level of the brain itself, we'll have to remain uncertain.",The other aperture (referred to as the decline-the-test response) led to the omission of the duration test.,"It may be just as simple for a bee (or any other animal) brain to compute uncertainty as it would be to classify and associate outcomes. Until we examine uncertainty at the level of the brain itself, we'll have to remain uncertain. Whether an insect monitors uncertainty or only appears to, honey bees are able to selectively avoid making decisions when information is limited.","By contrast, more widely spaced intervals (e.g., 2 and 8 s) are easiest to classify. The other aperture (referred to as the decline-the-test response) led to the omission of the duration test. In the test phase, a correct lever press with respect to the duration discrimination produced a large reward of six pellets; an incorrect lever press produced no reward.",[1],Biology,train,1.0,news,http://www.livescience.com/41255-what-bees-dont-know-can-help-them-measuring-insect-indecision.html
10.1016/j.neuron.2014.05.028,Biology_easy_93,"Also, we found that the cells that express Tac2 are distinct from those other investigators had previously identified as being involved in fear expression.""",Our data also suggest that amygdala cell culture with osanetant increases Nk3R mRNA levels.,"""It was interesting that Tac2 is highly expressed in one particular part of the amygdala, but with low or no expression in other brain areas related to the formation of fear memories. Also, we found that the cells that express Tac2 are distinct from those other investigators had previously identified as being involved in fear expression."" ""Osanetant is a safe and well-tolerated drug in humans and could be potentially used to prevent PTSD when given shortly after trauma, although more research is needed,"" Andero says.","The second is that Tac2 mRNA and/or NkB are transported from the CeM to other nuclei within the amygdala such as CeL, CeC, or BLA, where they bind to the Nk3R. Our data also suggest that amygdala cell culture with osanetant increases Nk3R mRNA levels. The most likely interpretation is that osanetant antagonizes amygdala Nk3R and due to its decreased availability, Nk3R mRNA is increased to synthesize more Nk3R in a compensatory manner.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41568-018-0020-9,Biology_easy_94,"PU-H71 specifically targets the epichaperome, present in over half of all cancers tested by Samus and the Chiosis group at Memorial Sloan Kettering Cancer Center, to precisely interfere with the epichaperome function in diseased cells and to not affect normal cells.",The oligomers retain ATPase and holdase activity but have a reduced ability to refold substrate and do not respond to stimulation by HSP40 (DnaJ in E. coli) 170 .,"PU-H71 specifically targets the epichaperome, present in over half of all cancers tested by Samus and the Chiosis group at Memorial Sloan Kettering Cancer Center, to precisely interfere with the epichaperome function in diseased cells and to not affect normal cells. PU-H71 is now being studied in Phase 1b combination trials in myelofibrosis and advanced metastatic breast cancer. ""In myelofibrosis, the epichaperome plays a central role in optimizing the JAK-STAT pathway, allowing JAK2 to form dimers that evade inhibition with a JAK2 inhibitor such as ruxolitinib.",Formation of the oligomeric form is associated with a conformational change in AtTDX structure 169 . The oligomers retain ATPase and holdase activity but have a reduced ability to refold substrate and do not respond to stimulation by HSP40 (DnaJ in E. coli) 170 . The large oligomers represent the active form and are plausibly responsible for underlying oncogenic functions owing to their ability to inhibit apoptosis and dampen the effects of oxidative stress .,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34294149057&p=1pl&v=1&x=pzihluZRVcZJ0XNPGmH0Mw
10.1126/sciadv.1601660,Biology_easy_96,"Going forward, Hart and his team plan to pursue the possibility of fully printed electronics.",The surface compliance enables the CNTs to conformally contact the target substrate during printing.,"This, combined with a tenfold improvement in the printing resolution that we demonstrated, is encouraging."" After annealing, or heating, the designs after stamping -- a common step in activating electronic features -- the printed patterns were indeed highly conductive, and could serve, for example, as high-performance transparent electrodes. Going forward, Hart and his team plan to pursue the possibility of fully printed electronics.","S4 ), the surface modulus (~32 MPa) is comparable to the compressive modulus. The surface compliance enables the CNTs to conformally contact the target substrate during printing. Also, the CNT microstructure matches the dimensions of the catalyst pattern, yet the plasma treatment etches both the top and sidewalls of the CNT microstructures, slightly narrowing their width ( fig.",[1],Biology,train,1.0,news,http://news.mit.edu/2016/stamping-technique-printable-electronics-1207
10.1038/s41467-018-04627-5,Biology_easy_99,"For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors.","In line with these results, scores on the TOWRE Index, a timed measure of reading, improved substantially (F(1,77) = 53.69, p < 10 −9 ), as did scores on the Woodcock-Johnson Reading Fluency subtest (F(1,76) = 36.042, p < 10 −7 ).","In the majority of these subjects, diffusion rates decreased in the arcuate and inferior longitudinal fasciculus. For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors. The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said.","After 8 weeks, the intervention-group mean was within one standard deviation of the population norm (100+/−15): pre-vs. post-intervention scores were 80.00+/−3.50 vs. 92.94+/−2.50). In line with these results, scores on the TOWRE Index, a timed measure of reading, improved substantially (F(1,77) = 53.69, p < 10 −9 ), as did scores on the Woodcock-Johnson Reading Fluency subtest (F(1,76) = 36.042, p < 10 −7 ). In contrast, we found no evidence for change in math skills during the intervention (Woodcock-Johnson Calculation Score, F(1,63) = 2.54, p = 0.12; Woodcock-Johnson Math Fact Fluency: F(68) = 1.87, p = 0.18), confirming that the intervention specifically affected reading skills.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1016/j.cell.2015.07.058,Biology_easy_100,This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability.,"The levels of virus genomes in WT, DE1B-55K, and DE4-ORF3-infected cells are 10 4 times higher than in DE1B-55K/DE4-ORF3-virus-infected cells ( Figure 1E ).","MRN starts a domino effect, activating histones on surrounding chromosomes, which summons a cascade of additional proteins, resulting in a cell-wide, all-hands-on-deck alarm to help mend the DNA. This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability. Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea.","These data suggest that global DDR signaling is activated independently of MRN in WT, DE1B-55K and DE4-ORF3-virus-infected cells. The levels of virus genomes in WT, DE1B-55K, and DE4-ORF3-infected cells are 10 4 times higher than in DE1B-55K/DE4-ORF3-virus-infected cells ( Figure 1E ). We conclude that E1B-55K or E4-ORF3 is required for viral genome replication.",[1],Biology,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1038/s41467-017-01957-8,Biology_easy_101,"The study shows that, surprisingly, more prey diversity does not always mean more predator diversity.","When the growth-defense trade-off is concave, a small cost of prey growth leads to a large gain of defense, thus we say the defense is cheap; when it is convex, defense is costly.","""This is, of course, beneficial to the prey and could reduce the pressure on the bacteria"", says Becks. The study shows that, surprisingly, more prey diversity does not always mean more predator diversity. As our experiments demonstrate, they can shift depending on whether or not the predator had time to adapt.""","Note, we used a similar power function to fit the trade-off curves from our experimental data and found a good agreement between the function and the data. When the growth-defense trade-off is concave, a small cost of prey growth leads to a large gain of defense, thus we say the defense is cheap; when it is convex, defense is costly. While possible mechanisms other than Fig.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.1073/pnas.1414221111,Biology_easy_103,"""This rapid clearance response depends on the presence of both the parasite and the investigational drug.","null mice (9) with (+)-SJ733 caused rapid clearance of parasites, which were 80% depleted within the first 24 h and undetectable by 48 h (Fig.","""The data suggest that compounds targeting ATP4 induce physical changes in the infected red blood cells that allow the immune system or erythrocyte quality control mechanisms to recognize and rapidly eliminate infected cells,"" DeRisi said. ""This rapid clearance response depends on the presence of both the parasite and the investigational drug. Planning has begun to move (+)-SJ733 from the laboratory into the clinic beginning with a safety study of the drug in healthy adults.","The data are consistent with the primary growth inhibition effects of (+)-SJ733 stemming from its ability to increase [Na + ] i through inhibition of PfATP4. null mice (9) with (+)-SJ733 caused rapid clearance of parasites, which were 80% depleted within the first 24 h and undetectable by 48 h (Fig. Notably, (+)-SJ733 cleared parasites faster than artesunate in the same model.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/12/141205175027.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.3945/jn.113.188441,Biology_easy_104,"Pero eso no es todo, ademas de elevar el colesterol, tambien aumenta los trigliceridos y provoca sindrome metabolico.","It is interesting to see that there was a simultaneous increase in both healthy metabolic components (HDL cholesterol increase, TG decrease) and some unhealthy metabolic components (abdominal obesity, LDL cholesterol increase) with the MP.","Esto se presenta porque este tipo de sopas incrementan el colesterol en la sangre y esto puede obstruir las arterias, las cuales transportan el flujo sanguineo y al oxigeno en el cuerpo. Pero eso no es todo, ademas de elevar el colesterol, tambien aumenta los trigliceridos y provoca sindrome metabolico. Esto ademas de provocar problemas cardiovasculares, pues independientemente de aumentar le presion arterial tambien eleva la glucosa en la sangre, lo cual puede provocar diabetes.","The TP, rich in fruit, vegetables, and fish, was inversely associated with abdominal obesity and elevated blood pressure, which is in agreement with previous studies . It is interesting to see that there was a simultaneous increase in both healthy metabolic components (HDL cholesterol increase, TG decrease) and some unhealthy metabolic components (abdominal obesity, LDL cholesterol increase) with the MP. The direct association with increased HDL cholesterol and a decrease in TGs with the MP might be mediated by a reduced intake of carbohydrates , such as polished rice , and an increased intake of fat among those in the highest quintile of the MP; there were similar findings in a Japanese population .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39561372381&p=1pl&v=1&x=lNU4nCAJSUXMnFz01j2kDA
10.1186/1471-2164-15-599,Biology_easy_105,"""If a mutation or a change increases the chances of survival in the person carrying it, this mutation will tend to become prevalent in the population.","Taken together, our results strongly indicate that positive selection in neural genes is likely to have played a significant role in the human evolution.","This provides researchers with a new vision on human evolution. ""If a mutation or a change increases the chances of survival in the person carrying it, this mutation will tend to become prevalent in the population. The new protein will have changed its function compared to the ancestral protein.","None of these classes achieved statistical significance, except synapse in the accelerated gene set, with five observed genes compared to one expected by chance (proportion test, p < 10 −3 ). Taken together, our results strongly indicate that positive selection in neural genes is likely to have played a significant role in the human evolution. Comparing the number of non-synonymous and synonymous substitutions in sister species can help identify sequences that have been the target of positive selection in one of the species.",[1],Biology,train,1.0,news,http://www.healthcanal.com/genetics-birth-defects/53316-identified-almost-200-genes-that-have-evolved-more-rapidly-in-humans-than-in-other-primates.html
10.1038/s41467-019-09863-x,Biology_easy_106,"But as the new research demonstrates, accounting for the possibility that they may occur is an important step in making sure that policymakers are prepared for all the potential outcomes.","Combined, these two factors lead to significant increases in the mean discounted economic effect of climate change: +4.0% ($24.8 trillion) under the 1.5°C scenario, +5.5% ($33.8 trillion) under the 2°C scenario, and +4.8% ($66.9 trillion) under mitigation levels consistent with the current national pledges.","""It could be a regular, linear increase in temperature without any dramatic threshold change, and suddenly it triggers this kind of social response which is very disproportionately large,"" he said. But as the new research demonstrates, accounting for the possibility that they may occur is an important step in making sure that policymakers are prepared for all the potential outcomes. ""It's important to keep it in people's minds that not all these changes might be these gradual linear changes,"" Jina said.","Combined, these two factors lead to significant increases in the mean discounted economic effect of climate change: +4.0% ($24.8 trillion) under the 1.5°C scenario, +5.5% ($33.8 trillion) under the 2°C scenario, and +4.8% ($66.9 trillion) under mitigation levels consistent with the current national pledges. Considering the nonlinear Arctic feedbacks makes the 1.5°C target marginally more economically attractive than the 2°C target, although both are statistically equivalent. T he Arctic region is warming twice as fast as the global average 1 , manifested by a decrease in sea ice, snow and glaciers and permafrost degradation relative to their benchmark average states for the period between 1979 and 2005 .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1016/j.cmet.2015.02.003,Biology_easy_107,"It also may reflect persistent, low-level inflammation connected with age-related diseases, including heart disease and some cancers.","While the mechanisms by which Na + is concentrated within the infected skin remain unknown, we show in mice that the osmotic stress within the Na + -loaded interstitial fluid matrix boosts the antimicrobial host defense and thereby strengthens the antiinfectious barrier function of the skin.","[STORY: Cancer treatment from the vet]

The new study implied that age-related salt accumulation by the skin may be a response to falling cellular barriers and rising microbe accessibility. It also may reflect persistent, low-level inflammation connected with age-related diseases, including heart disease and some cancers. In this case, it may be helpful to combat age-related increase in salt stores, the researchers suggested.","Because direct interstitial fluid collections for osmolality measurements in our patients were not possible in this non-invasive clinical 23 Na MRI study, additional experiments will be necessary to address the relevance of these findings to human disease. While the mechanisms by which Na + is concentrated within the infected skin remain unknown, we show in mice that the osmotic stress within the Na + -loaded interstitial fluid matrix boosts the antimicrobial host defense and thereby strengthens the antiinfectious barrier function of the skin. The increased cutaneous Na + concentrations in HSD mice improved L. major killing in the Na + reservoir.",[1],Biology,train,1.0,news,http://www.redorbit.com/news/health/1113346345/salty-skin-may-ward-off-infection-030415/
10.1038/s41598-017-05868-y,Biology_easy_108,"Importantly, the team found that pericytes produced 40-times more leptin when exposed to low levels of oxygen and that this continued until oxygen levels returned to normal.","Next, by screening the networks encompassing the highest number of genes regulated in the dataset ( Supplementary Table IV ), we found that LEP is modulated together with other 18 genes in a network of 29 genes, whose function is associated with cell death/apoptosis and cell-to-cell signalling/interaction ( Supplementary Table V ).","In the longer term, these findings may help in the development of an alternative treatment to major surgery for heart attack patients. Importantly, the team found that pericytes produced 40-times more leptin when exposed to low levels of oxygen and that this continued until oxygen levels returned to normal. This may help tissues to build more blood vessels to increase blood flow and oxygen supply.","In addition, using the Ingenuity Pathway Analysis (IPA) software, we found that LEP is associated with all the main biofunctions/pathways found to be significantly modulated by hypoxia, including the regulation of cell death and survival, development, energy production and tissue morphology (Supplementary Figure II) . Next, by screening the networks encompassing the highest number of genes regulated in the dataset ( Supplementary Table IV ), we found that LEP is modulated together with other 18 genes in a network of 29 genes, whose function is associated with cell death/apoptosis and cell-to-cell signalling/interaction ( Supplementary Table V ). To the best of our knowledge, this is the first report on the global gene signature induced by low oxygen in human APCs.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/new-discovery-could-reverse-tissue-damage-caused-by-heart-attacks/
10.1016/j.cub.2013.11.012,Biology_easy_109,"""Two weeks is not a long time at all"" to gain a specific new motor skill, let alone boost a whole set of them.","However, the computer users, compared to the non-computer-user group, generalize much more into other directions [interaction effect F(8, 96) = 6.9, p < 0.0001; main effect on groups F(2, 24) = 12.5, p < 0.0001, two-way ANOVA; Figure 2B ].","""The results are surprising,"" says Robert Scheidt, a biomechanical engineer at Marquette University in Milwaukee, Wisconsin, who works with stroke victims. ""Two weeks is not a long time at all"" to gain a specific new motor skill, let alone boost a whole set of them. So for those helping rehabilitate people who have lost motor abilities, ""this is exactly the result we wanted to see,"" Scheidt says.","It affected neither the speed of learning [F(8,18) = 0.91, p = 0.53, one-way ANOVA] nor the degree of learning [F(8,18) = 0.77, p = 0.64; Figure 2A ]. However, the computer users, compared to the non-computer-user group, generalize much more into other directions [interaction effect F(8, 96) = 6.9, p < 0.0001; main effect on groups F(2, 24) = 12.5, p < 0.0001, two-way ANOVA; Figure 2B ]. Interestingly, non-computer users still have a broad generalization as their generalization is significantly larger than zero even at the largest angular separation of 180 (30.0% 6 6.9%; p < 0.001, one-sample t test).",[1],Biology,train,1.0,news,http://news.sciencemag.org/brain-behavior/2013/12/click-here-improve-your-motor-skills
10.1038/s41467-018-05229-x,Biology_easy_110,"""In perfect insulators and semiconductors, electronic states expand throughout the entire crystal.","Interestingly, the abrupt shift of the absorption edge from E 0 = 1.42 eV to 2.1 eV occurring at ultrahigh electric bias fields might indeed relate to genuine electronic transitions of isolated constituent atoms ground state.","If this state is maintained for too long, the beads will break apart and the crystal dissolves. ""In perfect insulators and semiconductors, electronic states expand throughout the entire crystal. ""If the electric field inside the crystal is strong enough, the electronic states can be localized to a few atoms.","Consequently, we regard this fact as direct evidence for Wannier-Stark localization. Interestingly, the abrupt shift of the absorption edge from E 0 = 1.42 eV to 2.1 eV occurring at ultrahigh electric bias fields might indeed relate to genuine electronic transitions of isolated constituent atoms ground state. First-principles local density calculations of the electronic structure of GaAs show that the topmost valence bands are composed almost exclusively of 4p orbitals of the As atoms, while the first conduction band exhibits strong contributions from both As and Ga. Consequently, some net transfer of electronic charge from As to Ga upon absorption of a photon may be required to establish the minimum transition energy at the fundamental E 0 gap.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34669971079&p=1pl&v=1&x=vdqBVutlRrBG6NrsU9ADLw
10.1016/j.neuron.2018.12.026,Biology_easy_111,"Mouse models have helped a lot, he said.","Fmr1 À/y mice show spatially broader cortical activation to single-whisker stimulation, implying a blurred whisker map .","But it is not a single gene, it is hundreds of genes. Mouse models have helped a lot, he said. In all the mice, inhibition was lower than normal, and excitation was also lower, though less so, leading to an increase in the excitation-inhibition ratio.","*p = 0.03, **p << 0.001, ***p << 0.0001, t test. Fmr1 À/y mice show spatially broader cortical activation to single-whisker stimulation, implying a blurred whisker map . Consistent with map blurring, we found that the fraction of whiskerresponsive L2/3 RS units that were tuned to the columnar whisker was lower in Fmr1 À/y mice (Fmr1 +/y 0.53, Fmr1 À/y 0.24, p = 0.024, c 2 test) ( Figure 6G ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.2337/db13-1600,Biology_easy_112,"The paper by Donovan and Watts' team is the first to link peripheral glucose sensing with brain activation during hypoglycemia, a critical step in allowing the body to restore normal blood sugar levels.","Insulin infusion led to an increase in the arterial plasma insulin concentration, 4,930 6 699 pmol/L that was not significantly different between groups (P .","Each of their findings, which could have far-reaching consequences for the development of insulin therapies for Type 1 and Type 2 diabetes, is presented in two papers published together online on April 11 and 16 in the journal Diabetes. The paper by Donovan and Watts' team is the first to link peripheral glucose sensing with brain activation during hypoglycemia, a critical step in allowing the body to restore normal blood sugar levels. This in turn lowers levels of glucose in the blood.","No significant differences in body weight were observed between experimental groups on the day of experiments. Insulin infusion led to an increase in the arterial plasma insulin concentration, 4,930 6 699 pmol/L that was not significantly different between groups (P . 0.10) (Fig.",[1],Biology,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1038/s41396-017-0042-4,Biology_easy_114,"The team found far fewer bacteria above the planetary boundary layer, with only tens of millions deposited per square meter.","The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere.","The results shed light on the way these viruses spread across the planet. The team found far fewer bacteria above the planetary boundary layer, with only tens of millions deposited per square meter. This might all sound terrifying, but the authors actually believe such a microbe transportation mechanism can help ecosystems thrive.","Therefore, these relationships between the size fractions of the organic aerosols and the virus and bacteria deposition rates could be also determined by the origin of air masses. The daily deposition rates of viruses associated with aerosols <0.7 μm in size explains observations that identical viral sequences occur at geographically distant locations and in very different environments , likely as a consequence of long persistence and dispersal in the atmosphere. This provides a mechanism for maintaining the very high diversity of viruses, as well as bacteria observed at a local level but constrained globally, consistent with a seedbank model.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33225111907&p=1pl&v=1&x=66SNTCt_ZJdMnc3SIBgGKQ
10.1038/s41467-019-09863-x,Biology_easy_115,"""These two components are set to peak for global temperatures within the range covered by the Paris Agreement, but if the climate warms further, the summer and spring sea ice and land snow covers will retreat further north and the albedo feedback will actually weaken.""","46 , projected onto the 8 major regions of the PAGE model using population-weighted temperatures, and adapted to fit with the single year consumption-only approach for climate impacts used in PAGE; second, considerably downscaled saturation limit for the impacts; third, modified uncertainty range for the BaU scenario, which is used as a reference point for calculating the abatement costs, covering the range roughly between RCP6.0 and a pathway exceeding RCP8.5; 23 fourth, revised present-day marginal abatement cost (MAC) curves 64 , technological learning rate (CO 2 only) 65 and autonomous technological change based on energy efficiency improvements; 91 fifth, significantly downscaled discontinuity sector, which now accounts only for socio-economic tipping points such as pandemics, mass migration and wars, as well as possible other tipping points in the climate than permafrost, sea ice, land snow and lea level rise from ice sheets (the catastrophic loss of the ice sheets has been moved to the fat-tailed distribution in the sea level rise module); sixth, reduced tolerable temperature rise that gives no chance of a discontinuity; seventh, significantly decreased time constant of a discontinuity in line with its new interpretation; eighth, focus on autonomous adaptation as part of the Burke et al.","Furthermore, the strength of both is constantly changing in nonlinear ways as the climate warms. ""These two components are set to peak for global temperatures within the range covered by the Paris Agreement, but if the climate warms further, the summer and spring sea ice and land snow covers will retreat further north and the albedo feedback will actually weaken."" He adds that they found permafrost feedback becomes progressively stronger in climates that are warmer.","This allows us to work with MonteCarlo generated probability distributions of multiple climatic and economic parameters in any fixed analysis year like 2100, as opposed to taking averages over the 30-year climatological windows (a standard requirement for any climate model data with multiple natural variability cycles). 46 , projected onto the 8 major regions of the PAGE model using population-weighted temperatures, and adapted to fit with the single year consumption-only approach for climate impacts used in PAGE; second, considerably downscaled saturation limit for the impacts; third, modified uncertainty range for the BaU scenario, which is used as a reference point for calculating the abatement costs, covering the range roughly between RCP6.0 and a pathway exceeding RCP8.5; 23 fourth, revised present-day marginal abatement cost (MAC) curves 64 , technological learning rate (CO 2 only) 65 and autonomous technological change based on energy efficiency improvements; 91 fifth, significantly downscaled discontinuity sector, which now accounts only for socio-economic tipping points such as pandemics, mass migration and wars, as well as possible other tipping points in the climate than permafrost, sea ice, land snow and lea level rise from ice sheets (the catastrophic loss of the ice sheets has been moved to the fat-tailed distribution in the sea level rise module); sixth, reduced tolerable temperature rise that gives no chance of a discontinuity; seventh, significantly decreased time constant of a discontinuity in line with its new interpretation; eighth, focus on autonomous adaptation as part of the Burke et al. economic impact function, with planned adaptation restricted to SLR impacts.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39064299256&p=1pl&v=1&x=uiRMkpkYPuCChqjw9RPdQw
10.1016/j.neuron.2018.12.026,Biology_easy_116,"He views this as a highly effective accommodation by neurons to these genetic mutations, representing the brain's normal compensation mechanism for restoring neuronal activity.","Fmr1 À/y mice show faster or broader spread of sensory-evoked activity in S1, suggesting a blurred whisker map (Arnett et al., 2014; , which we also observed in the form of increased tuning heterogeneity in each S1 column.","This was because the changes in inhibition and excitation were precisely coordinated to offset each other. He views this as a highly effective accommodation by neurons to these genetic mutations, representing the brain's normal compensation mechanism for restoring neuronal activity. But decreased inhibition may have unwanted secondary effects that impair other aspects of neural information processing, such as the tuning each neuron has to specific stimuli.","Thus, increased cortical spiking is not broadly observed in ASD genotypes. Fmr1 À/y mice show faster or broader spread of sensory-evoked activity in S1, suggesting a blurred whisker map (Arnett et al., 2014; , which we also observed in the form of increased tuning heterogeneity in each S1 column. A simple synaptic conductance model explains why increased E-I conductance ratio does not generate stronger PSPs or more spiking in ASD mutants: in all 4 ASD genotypes, the decreases in inhibitory and excitatory conductances were precisely counterbalanced to maintain constant PSPs for Vm just below spike threshold.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1038/s41467-018-04627-5,Biology_easy_117,"Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said.","In this view, differences in white matter properties could be considered a reflection of intrinsic deficits, which might be relatively resistant to remediation, but which could plausibly be used for early identification of individuals in need of extra educational support.","The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said. Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said. For example, the measurements might be picking up on increases in the number or size of certain types of cells that help nourish and maintain the white matter, or on added insulation for existing neural connections, Huber said.","The implication of these observations is that underlying anatomical differences may predestine certain individuals to struggle with learning to read. In this view, differences in white matter properties could be considered a reflection of intrinsic deficits, which might be relatively resistant to remediation, but which could plausibly be used for early identification of individuals in need of extra educational support. Successfully relating anatomical differences with behavioral outcomes requires an understanding of the timescale over which white matter tissue properties exhibit experience-dependent change and the anatomical specificity of these effects.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1016/j.cmet.2015.02.003,Biology_easy_118,"""A further understanding of the regulatory cascades might not only help to design drugs that specifically enhance local salt deposition and help to combat infectious diseases,"" Jantsch said, ""but also may lead to novel strategies to mobilize sodium stores in the aging population and prevent cardiovascular disease.",Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation.,"The findings, though, may lead to a supplement version of sodium in order to protect the heart and other organs from the negative impacts high-salt diets have on the body, while still achieving a positive immunal response. ""A further understanding of the regulatory cascades might not only help to design drugs that specifically enhance local salt deposition and help to combat infectious diseases,"" Jantsch said, ""but also may lead to novel strategies to mobilize sodium stores in the aging population and prevent cardiovascular disease. We also think that local application of high-salt-containing wound dressings and the development of other salt-boosting antimicrobial therapies might bear therapeutic potential.""",We found that Na + accumulated at the site of bacterial skin infections in humans and in mice. Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control.,[1],Biology,train,1.0,news,http://www.medicaldaily.com/blood-pressure-and-heart-condition-risks-aside-high-salt-diets-may-improve-immune-324200
10.1016/j.cell.2013.08.004,Biology_easy_119,Findings published online in the journal Cell possibly unveil a cure for jet lag and shift work disorders.,"We observed a 10.90 ± 1.02 hr phase delay of the PER2::LUC rhythm in I3M-treated cells, compared with 7.59 ± 1.00 hr delay in the control, a difference of 3.3 hr ( Figures 3D and 3E) .",Findings published online in the journal Cell possibly unveil a cure for jet lag and shift work disorders. The researchers identified approximately 100 genes that the body switches on in response to light. The mice were found to adjust more quickly to the changes in the daily patterns of light and dark that were set to resemble those of a time zone change.,"These data support our hypothesis that SIK1 acts to modulate the magnitude of phase shifts via the negative regulation of CREB-mediated transcription of Per1. We observed a 10.90 ± 1.02 hr phase delay of the PER2::LUC rhythm in I3M-treated cells, compared with 7.59 ± 1.00 hr delay in the control, a difference of 3.3 hr ( Figures 3D and 3E) . The rhythms of SCN treated with I3M peaked approximately 1 hr later than DMSO-treated controls ( Figure 3F ).",[1],Biology,train,1.0,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1098/rsbl.2018.0564,Biology_easy_120,"In this new effort, the researchers have improved upon earlier models built to mimic the behavior of the bridge and learned more about the shaking and swaying.",This simplification is justified because the steady-state bridge and pedestrian motions depend on N but not P (figure 2a).,"All of those people reacting caused a feedback loop which made the bridge unstable. In this new effort, the researchers have improved upon earlier models built to mimic the behavior of the bridge and learned more about the shaking and swaying. But that model was not able to factor in the energy cost of an individual working to stabilize their gait.","In this case, the biped cannot affect the walking surface motion. This simplification is justified because the steady-state bridge and pedestrian motions depend on N but not P (figure 2a). In all simulations, the initial phase difference between the walkers and the bridge was random and had no effect on any of the steady-state results here.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37552102568&p=1pl&v=1&x=Dbgz3q4yV3xVG-LM5dPKZA
10.1139/cjz-2017-0071,Biology_easy_121,"""This individual was likely persisting via opportunistic foraging around Grand Forks residents' homes whenever temperatures reached above freezing.""","However, opossums have been observed beyond the temperature niche Brocke prescribed , and the top models in our study suggest that opossum populations are more impacted by the presence and longevity of snow than by harsh winter temperatures.","""The winter temperatures and the individual's condition suggest that this opossum spent much of the winter in a den rather than foraging,"" Walsh says. ""This individual was likely persisting via opportunistic foraging around Grand Forks residents' homes whenever temperatures reached above freezing."" In this way, increased access to food in urban and suburban areas and near farms might be increasing winter foraging success and allowing the Virginia opossum to expand into northerly areas that would otherwise be intolerable.","Temperature could have once been the limiting factor (Brocke 1970), but it may now be overcome by the increased presence of agriculture in areas with dangerously low winter temperatures. However, opossums have been observed beyond the temperature niche Brocke prescribed , and the top models in our study suggest that opossum populations are more impacted by the presence and longevity of snow than by harsh winter temperatures. The analysis of human variables and how they are related to diversity measurements suggest that agricultural lands are providing significant resources for Midwestern opossums and with D r a f t substantial gene flow across the study area, it appears that little is limiting the dispersal of opossums in this region apart from time.",[1],Biology,train,1.0,news,http://www.futurity.org/virginia-opossum-range-1684512/
10.1073/pnas.1704745114,Biology_easy_122,The separation of these parts in the seed 'brain' also appears to be central to how it functions.',These lines ultimately lead toward convergence points that represent a stable resting state of the system.,"Lead author of the study, Professor George Bassel from the School of Biosciences at the University of Birmingham, says: 'Our work reveals a crucial separation between the components within a plant decision-making centre. The separation of these parts in the seed 'brain' also appears to be central to how it functions.' The mathematical theory describing the brain's function predicted that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, than to constant environments.",1  B and C) . These lines ultimately lead toward convergence points that represent a stable resting state of the system. The shape of Significance Both plants and animals make decisions in response to the environment to maximize their fitness.,[1],Biology,train,1.0,news,http://www.seeddaily.com/reports/Scientists_discover_plant_brain_controlling_seed_development_999.html
10.1038/s41467-018-04355-w,Biology_easy_123,"Pecot said they want to continue investigating this strategy, and potentially other ways of preventing clotting within tumors, to see if it prevents metastases from initiating and whether it can stall the process once it has begun.","Notably, we show that IMs highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for LUSC cell invasion and metastases.","They saw a significant decrease in lung metastases. Pecot said they want to continue investigating this strategy, and potentially other ways of preventing clotting within tumors, to see if it prevents metastases from initiating and whether it can stall the process once it has begun. ""The more we understand the progression of the disease, including how metastases occurs, the more we'll be able to understand how we can regress this disease, or just keep it in check.","Pharmacologic inhibition of IM recruitment had substantial anti-metastatic effects. Notably, we show that IMs highly express Factor XIIIA, which promotes fibrin cross-linking to create a scaffold for LUSC cell invasion and metastases. Consistently, human LUSC samples containing extensive crosslinked fibrin in the microenvironment correlated with poor survival.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34143256224&p=1pl&v=1&x=_B116Taw-aRVfBzYTF8X0Q
10.1016/j.cmet.2015.02.003,Biology_easy_124,"""I think that the most important finding here is that tissues can accumulate massive amounts of sodium locally to boost immune responses where ever needed,"" Titze said.",This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control.,"[STORY: Challenging convention: Visual cortex not solely responsible for processing images]

Despite the positive results, researchers warned that a high-salt diet should not be seen as a healthy regular routine. ""I think that the most important finding here is that tissues can accumulate massive amounts of sodium locally to boost immune responses where ever needed,"" Titze said. ""This mostly happens totally independent of the diet.""","Activation of macrophages in the presence of high NaCl concentrations modified epigenetic markers and enhanced p38 mitogen-activated protein kinase (p38/MAPK)-dependent nuclear factor of activated T cells 5 (NFAT5) activation. This high-salt response resulted in elevated type-2 nitric oxide synthase (Nos2)-dependent NO production and improved Leishmania major control. Finally, we found that increasing Na + content in the skin by a high-salt diet boosted activation of macrophages in a Nfat5-dependent manner and promoted cutaneous antimicrobial defense.",[1],Biology,train,1.0,news,http://www.redorbit.com/news/health/1113346345/salty-skin-may-ward-off-infection-030415/
10.1038/s41467-019-09863-x,Biology_easy_125,"The economic growth of warmer nations such as Sudan, India, Nigeria, and Brazil has been stunted by about 25-36 percent due to climate change, the study found.","In contrast, the SAF for the rest of the world stays nearly constant until high GMST anomalies.","Such measures include widespread adoption of renewable energies such as solar power, the study said. The economic growth of warmer nations such as Sudan, India, Nigeria, and Brazil has been stunted by about 25-36 percent due to climate change, the study found. ""Although between-country inequality has decreased over the past half century, there is ~90 percent likelihood that global warming has slowed that decrease,"" the authors said.","The plateau in the sea ice SAF component between 5-7°C coincides with the loss of the spring sea ice 40 . In contrast, the SAF for the rest of the world stays nearly constant until high GMST anomalies. The SAF emulator models the global SAF as a function of the GMST (Methods), reproducing the nearly monotonic decline driven largely by the Arctic sea ice and land snow components.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39063152220&p=1pl&v=1&x=rfZKa3AOnuRs3Dq6otYxhw
10.1186/s12944-018-0743-3,Biology_easy_131,"""In general, the more exercises you have, the 'easier' the workout is since you will be working different muscle groups compared with just two exercises back-to-back that would fatigue those muscle groups pretty quickly,"" Ryan says.","The present study demonstrates that circuit training at home affects the bone mass as well as other factors, The age at which menstruation started b t-score by an unpaired t-test (two-sided test) showed the differences between the baseline and either 2 or 3 months after baseline [ †] indicates a significant relationship between the baseline and the time of follow-up; † < 0.05 such as the muscle mass and body fat percentage, among undergraduate female students.","The opposite happens when you do a triceps press. ""In general, the more exercises you have, the 'easier' the workout is since you will be working different muscle groups compared with just two exercises back-to-back that would fatigue those muscle groups pretty quickly,"" Ryan says. What's also great about circuit training is that you can combine cardio with strength.","The results showed a positive effect of body fat percentage on the calcaneus QUS-SI (p = 0.009) 3 months later, also shown in Table 4 . The present study demonstrates that circuit training at home affects the bone mass as well as other factors, The age at which menstruation started b t-score by an unpaired t-test (two-sided test) showed the differences between the baseline and either 2 or 3 months after baseline [ †] indicates a significant relationship between the baseline and the time of follow-up; † < 0.05 such as the muscle mass and body fat percentage, among undergraduate female students. In the nonexercising group, subjects attained a significantly higher calcaneus QUS-SI at 2 and 3 months from baseline, and in the exercising group, subjects attained a higher calcaneus QUS-SI at 3 months from baseline, albeit not a significantly higher value.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39028000354&p=1pl&v=1&x=rNZIkXnItgXmLxg4R0B21g
10.1373/clinchem.2012.187617,Biology_easy_133,"While Scott Kelly was in orbit, the microbes found in his gut shifted significantly from the kinds that the researchers found on the ground.","Thus, therapeutic modulation aimed at altering the gut microbiome may be beneficial in retarding the development of diabetes.","Conducting a fecal study in space is harder than you think. While Scott Kelly was in orbit, the microbes found in his gut shifted significantly from the kinds that the researchers found on the ground. Within a few months of his return to Earth, this change actually reversed, returning his microbiome to its ""normal"" state.","In BB rats (a model of type 1 diabetes), Lactobacillus species present in feces (L. johnsonii and L. reuteri) were negatively correlated with type 1 diabetes development , possibly via modulation of the intestinal mucosal protein and oxidative stress response leading to lower quantities of proinflammatory cytokines such as interferon ␥. Thus, therapeutic modulation aimed at altering the gut microbiome may be beneficial in retarding the development of diabetes. More than 30 billion nucleotide bases of Illumina shotgun metagenomic data were analyzed, and the findings revealed significantly increased proportions of pathways and modules involved in carbohydrate metabolism and stress responses in cases compared to controls.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1073/pnas.1404354111,Biology_easy_134,"""The progenitor and stem cells in the bone marrow began massively expanding and effectively turned the bone marrow into a megakaryocyte-making machine,"" he said.","This analysis revealed that genes associated with TPO overstimulation in TPO Tg LSKs were strongly correlated with up-regulated genes in Mpl PF4cre/PF4cre LSKs, whereas the gene signature associated with TPO starvation in Mpl −/− LSKs was associated with down-regulated genes in Mpl PF4cre/PF4cre LSKs (Fig.","Dr Ng said the result was very surprising. ""The progenitor and stem cells in the bone marrow began massively expanding and effectively turned the bone marrow into a megakaryocyte-making machine,"" he said. ""Our findings support a theory whereby megakaryocytes and platelets control platelet numbers by 'mopping up' excess amounts of thrombopoietin in the bone marrow.","which are expanded significantly in number, clear circulating TPO to levels observed in Mpl-replete mice, even in the absence of clearance by megakaryocytes and platelets. This analysis revealed that genes associated with TPO overstimulation in TPO Tg LSKs were strongly correlated with up-regulated genes in Mpl PF4cre/PF4cre LSKs, whereas the gene signature associated with TPO starvation in Mpl −/− LSKs was associated with down-regulated genes in Mpl PF4cre/PF4cre LSKs (Fig. This data confirms at a genetic level that Mpl expressing stem and progenitor cells in Mpl PF4cre/PF4cre mice were exposed to excessive TPO stimulation, explaining the behavior of their preprogenitor blast colonies at the single-cell level and the mechanistic basis for the myeloproliferation, megakaryocytosis, and thrombocytosis obverved in Mpl PF4cre/PF4cre mice.",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/49516-solution-to-platelet-%E2%80%98puzzle%E2%80%99-uncovers-blood-disorder-link.html
10.1038/s41467-018-04627-5,Biology_easy_135,"""We were able to detect changes in brain connections within just a few weeks of beginning the intervention program.",These results underscore the importance of considering recent experience when interpreting cross-sectional anatomy-behavior correlations.,"The study, published June 8 in Nature Communications, is the first to measure white matter during an intensive educational intervention and link children's learning with their brains' flexibility. ""We were able to detect changes in brain connections within just a few weeks of beginning the intervention program. ""In reality, different experiences can shape the brain in dramatic ways throughout development.""","Additionally, we identify tracts whose properties predict reading skill but remain fixed throughout the intervention, suggesting that some anatomical properties stably predict the ease with which a child learns to read, while others dynamically reflect the effects of experience. These results underscore the importance of considering recent experience when interpreting cross-sectional anatomy-behavior correlations. Widespread changes throughout the white matter may be a hallmark of rapid plasticity associated with an intensive learning experience.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1016/j.cmet.2015.02.003,Biology_easy_136,"That's not to say that you should switch to a high salt diet, though.",This hypertonic microenvironment was accompanied by a significant reduction of L. major burden at the end of the experiment (2 nd time point; Figure 4B ).,"The researchers found that infected areas in patients with bacterial skin infections also showed remarkably high salt accumulation. That's not to say that you should switch to a high salt diet, though. ""Due to the overwhelming clinical studies demonstrating that high dietary salt is detrimental to hypertension and cardiovascular diseases, we feel that at present our data does not justify recommendations on high dietary salt in the general population,"" said Jantsch.","Improved healing was paralleled by increased (Na + + K + )/H 2 O ratio in HSD mice ( Figure 4B ). This hypertonic microenvironment was accompanied by a significant reduction of L. major burden at the end of the experiment (2 nd time point; Figure 4B ). We found a tendency toward increased IFN-g production in HSD mice, suggesting that Leishmania-specific T cell responses may be involved in improved host defense with HSD ( Figure 4B ).",[1],Biology,train,1.0,news,http://www.scienceworldreport.com/articles/22963/20150304/high-salt-diet-ward-infection-invading-microbes.htm
10.1038/s41467-018-07557-4,Biology_easy_137,"""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality.""","For example, our results highlight critical areas such as the Pechora region, the northwestern parts of the Ural Mountains, northwest and central Siberia, the Yakutsk basin (except for the city of Yakutsk in low to moderate hazard area), as well as the central and western parts of Alaska to which high priority for local scale infrastructure hazard assessments should be performed in future decades 1 .","""These observations have led me to believe that the global warming is not a 'fake' but the reality,"" Romanovsky said. ""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The Paper May Be Misleading

Even though the researchers of this study insist that global warming threat is real, Christopher Burn, a professor of geography and environmental studies at Carleton University, Canada, explains that the paper does not reveal anything that they don't already know.","1 ), the regional differences appear less pronounced ( Fig. For example, our results highlight critical areas such as the Pechora region, the northwestern parts of the Ural Mountains, northwest and central Siberia, the Yakutsk basin (except for the city of Yakutsk in low to moderate hazard area), as well as the central and western parts of Alaska to which high priority for local scale infrastructure hazard assessments should be performed in future decades 1 . Considering different stabilization scenarios of climate warming, our analysis reveals that substantial cuts in global greenhouse gas (GHG) emissions now would not make a large difference for infrastructure risks in the highest hazard area by 2050.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37967333906&p=1pl&v=1&x=ltio0H7-Rr6r3LuvSX7DEA
10.1038/s41467-018-05709-0,Biology_easy_138,"Mice that were administered with the drug scratched themselves less often, and their skin changes healed significantly quicker than in animals that were given a placebo.","By contrast, biting responses in TPA023B (1 mg kg −1 , p.o.)","In their experiments, the pharmacologists were able to show that it not only suppresses acute itch, but is also effective against chronic itch. Mice that were administered with the drug scratched themselves less often, and their skin changes healed significantly quicker than in animals that were given a placebo. The same itch-suppressant effect was also observed in tests with dogs carried out by the researchers in cooperation with the University of Zurich's Veterinary Department.","Chloroquine-induced biting responses (total time spent biting the injected skin area) were virtually identical in all three genotypes (ANOVA followed by Bonferroni post-hoc test F(14,2) = 0.39, P = 1.0 for all comparisons). By contrast, biting responses in TPA023B (1 mg kg −1 , p.o.) treated mice differed significantly between genotypes (ANOVA followed by Bonferroni post-hoc test F(2,13) = 10.6).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34818663460&p=1pl&v=1&x=L-gib_N5MhiGEP62jfuz-g
10.1016/j.cell.2013.08.004,Biology_easy_139,"In one particular experiment, when the researchers blocked the activity of SIK1 in laboratory mice, the mice adjusted faster to changes in the light-dark cycle that mimic a time zone change.","In hippocampal neurons, CRTC1 functions as a sensor of stimulation, by traveling from the synapse to the nucleus in response to activation, triggering CREB mediated transcription and thereby regu-lating hippocampal plasticity .","In one particular experiment, when the researchers blocked the activity of SIK1 in laboratory mice, the mice adjusted faster to changes in the light-dark cycle that mimic a time zone change. The study proposes that the light-stimulated production of SIK1 in turn switches off the molecular pathway that feeds into the clock mechanism, thereby halting the shifting response of the biological clock. ""Our key contribution to the project was to manipulate the SIK1 protein pharmacologically, and we revealed that such blockage of the protein's activity in combination with exposure to a natural clock resetting agent, such as light, enhanced the clock shifting response,"" Duffield said.","For example, in skeletal myocytes, SIK1 functions as a Ca 2+ -responsive CREB-regulated HDAC kinase and a Ca 2+ -induced regulator of Na + transport in kidney cells . In hippocampal neurons, CRTC1 functions as a sensor of stimulation, by traveling from the synapse to the nucleus in response to activation, triggering CREB mediated transcription and thereby regu-lating hippocampal plasticity . An appreciation of the role of CRTC1-SIK1 regulation in these noncircadian pathways very much supports our interpretation of how this signaling pathway functions within the molecular clock.",[1],Biology,train,1.0,news,http://www.healthcanal.com/disorders-conditions/sleep/42436-researchers-identify-new-drug-target-for-treating-jet-lag-and-shift-work-disorders.html
10.1073/pnas.1318978111,Biology_easy_140,"Authors believe the study provides potential biological targets to enhance fertility in women with diminished ovarian reserve, who produce few or no follicles in response to IVF drugs designed to boost follicle development.","We show that, in GCs, androgens use a conserved nongenomic pathway to rapidly activate kinase signaling via transactivation of the EGF receptor.","Authors believe the study provides potential biological targets to enhance fertility in women with diminished ovarian reserve, who produce few or no follicles in response to IVF drugs designed to boost follicle development. ""Our study doesn't solve the controversy, but, along with some earlier seminal studies from other groups, it does tell us that we can't dismiss male hormones. They might actually be doing something useful.""","Importantly, few transcriptional targets of androgens have been identified in the ovary ; our results add to this short list by establishing miR-125b as a direct target of AR in GCs. We show that, in GCs, androgens use a conserved nongenomic pathway to rapidly activate kinase signaling via transactivation of the EGF receptor. Furthermore, we show that extranuclear AR signaling is required for AR-mediated transcriptional effects on miR-125b, confirming and adding to earlier data demonstrating that extranuclear androgen signaling is essential for AR nuclear localization and subsequent genomic androgen signaling .",[1],Biology,train,1.0,news,http://www.technology.org/2014/03/05/study-shows-male-hormones-play-important-role-female-fertility/
10.1093/pcp/pct167,Biology_easy_141,"""Not much is known about the way a grapevine supports the growth of the powdery mildew disease, but the frogs help us provide a reasonable hypothesis for what is going on and why Cabernet Sauvingon could be susceptible,"" Gassmann said.","With an Arabidopsis triple mutant that is susceptible to E. necator, we found that AtNPF3.1 is up-regulated in the leaves of infected Arabidopsis similarly to VvNPF3.2 in susceptible grapevine leaves.","His findings reveal one way that Vitis vinifera is genetically unable to combat the virus that causes powdery mildew. ""Not much is known about the way a grapevine supports the growth of the powdery mildew disease, but the frogs help us provide a reasonable hypothesis for what is going on and why Cabernet Sauvingon could be susceptible,"" Gassmann said. Gassmann says this research will open the door for discussing techniques to breed more resistant grapevines in the future.","We also cloned the Arabidopsis ortholog, AtNPF3.1, and showed that AtNPF3.1 similarly transported nitrate and nitrite with low affinity. With an Arabidopsis triple mutant that is susceptible to E. necator, we found that AtNPF3.1 is up-regulated in the leaves of infected Arabidopsis similarly to VvNPF3.2 in susceptible grapevine leaves. Expression of the reporter b-glucuronidase (GUS) driven by the promoter of VvNPF3.2 or AtNPF3.1 in Arabidopsis indicated that both transporters are expressed in vascular tissue, with expression in major and minor veins, respectively.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140430133139.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/scitranslmed.3008325,Biology_easy_143,"The rats walked more than 1,000 steps without failure, and could also climb staircases of various heights and lengths with fluid movements.",Precision of step height control significantly increased in variability ( fig.,"The investigators discovered a direct relationship between the frequency of electrical stimulation and how high rats lifted their limbs. The rats walked more than 1,000 steps without failure, and could also climb staircases of various heights and lengths with fluid movements. The scientists are planning a clinical trial that could start next summer to test such robot-assisted rehabilitation in patients with partially severed spinal cords.","Despite these multifaceted challenges, the controller successfully tuned EES frequency to instantly adjust step height to varying reference bands (movie S2). Precision of step height control significantly increased in variability ( fig. Human patients with SCI exhibit a rapid exhaustion of locomotor output during continuous stepping on a treadmill , which is also observed in injured rats .",[1],Biology,train,1.0,news,http://www.popularmechanics.com/science/health/nueroscience/prosthetics-are-telling-paralyzed-leg-how-to-walk-again-17243055
10.1038/s41467-018-06108-1,Biology_easy_145,"With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex.",Higher proportions of non-synonymous mutations were found to be at low frequency compared with synonymous mutations and no significant differences in the relative proportions were found between subgenomes (Fig.,"As a result, large-scale genetic changes are therefore possible in the new species, making it more adaptable in comparison with the parental species, as has now been proven by UZH researchers with rockcress. With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex. Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions.","halleri 25 , suggesting similar reductions in genetic diversity in the lineages of A. kamchatica and A. thaliana. Higher proportions of non-synonymous mutations were found to be at low frequency compared with synonymous mutations and no significant differences in the relative proportions were found between subgenomes (Fig. This suggests purifying selection on a large proportion of amino-acid-changing substitutions in both subgenomes.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/iSCNAuficZY/
10.1038/s41467-019-09863-x,Biology_easy_146,"However, the interdisciplinary team behind the research notes that if the world keeps the global temperature rise limited to 1.5 degrees Celsius, the additional economic impact drops to $25 trillion.","The two LSMs have markedly different responses to future climate change: SiBCASA appears to be on the upper end and JULES on the lower end of the reference multi-models studies 30 (Supplementary Note 2, Supplementary Fig.","Furthermore, the melting ice means that the Earth's surface is absorbing even more heat from the sun. However, the interdisciplinary team behind the research notes that if the world keeps the global temperature rise limited to 1.5 degrees Celsius, the additional economic impact drops to $25 trillion. This is at pre-industrial levels, which is consistent with international Paris Agreement target.","Considering the nonlinear PCF and SAF makes the pathways towards the lower end of the range covered by the Paris Agreement targets marginally more economically attractive. The two LSMs have markedly different responses to future climate change: SiBCASA appears to be on the upper end and JULES on the lower end of the reference multi-models studies 30 (Supplementary Note 2, Supplementary Fig. Their combined use here provides a suitable estimate of the range of permafrost responses arising from uncertainty in LSM parameterizations.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39064299256&p=1pl&v=1&x=uiRMkpkYPuCChqjw9RPdQw
10.1186/gb-2013-14-7-r73,Biology_easy_147,"""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics.""",The vlincRNAs associated with LTR promoters showed much higher tissue-specificity than either the nonrepeat or the non-LTR repeat-containing promoters ( Figure 1C ).,"The number of vlincRNAs expressed by these domesticated viral sequences correlates with both embryonic development and malignant cancers. ""Based upon this technology, we now have a greater understanding of transcriptome regulation, with potential to lead to therapeutic targets and better disease diagnostics."" The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues.","Interestingly, only LTR-type repeats appear to confer strong tissue-specific expression patterns on vlincRNAs. The vlincRNAs associated with LTR promoters showed much higher tissue-specificity than either the nonrepeat or the non-LTR repeat-containing promoters ( Figure 1C ). In addition, the vlincRNAs associated with LTR promoters had higher expression levels than vlincRNAs associated with other promoters ( Figure 1D ).",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130731093915.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1093/pcp/pct167,Biology_easy_148,His findings reveal one way that Vitis vinifera is genetically unable to combat the virus that causes powdery mildew.,Induction of AtNPF3.1 pro :GUS expression by E. necator in transgenic Arabidopsis was not tested because the mature leaf displayed a high level of GUS activity in the absence of infection.,"Gassmann found that the fungus is able to trick the grapevine into providing nutrients, which allows mildew to grow and devastate the plant. His findings reveal one way that Vitis vinifera is genetically unable to combat the virus that causes powdery mildew. ""Not much is known about the way a grapevine supports the growth of the powdery mildew disease, but the frogs help us provide a reasonable hypothesis for what is going on and why Cabernet Sauvingon could be susceptible,"" Gassmann said.","8D) , possibly suggesting redirection of nitrogen distribution by E. necator. Induction of AtNPF3.1 pro :GUS expression by E. necator in transgenic Arabidopsis was not tested because the mature leaf displayed a high level of GUS activity in the absence of infection. Our measurements of currents in response to nitrate by twoelectrode voltage clamp in Xenopus oocytes expressing VvNPF3.2 and AtNPF3.1 indicate that both proteins transport nitrate with low affinity, that VvNPF3.2 does not transport dipeptides and that VvNPF3.2 nitrate-responsive currents are dependent on low external pH.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140430133139.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2016.04.014,Biology_easy_149,"""By looking at these super-enhancers, we were able to identify a number of genes that are likely to be critical for eliminating pathogens, but which nobody had identified as important before.""",Colored circles highlight transcripts expressed at least 2-fold higher in a single tonsillar subset compared with the other three subsets.,"""This is the first time that these sets of super-enhancers had been mapped for these cell types,"" Oltz said. ""By looking at these super-enhancers, we were able to identify a number of genes that are likely to be critical for eliminating pathogens, but which nobody had identified as important before."" Furthermore, the researchers found that the super-enhancers contained many genetic variants associated with autoimmune diseases such as diabetes, rheumatoid arthritis, Crohn's disease and ulcerative colitis.","Although PCA underscored distinctions in transcriptional modules between innate and adaptive counterparts, ILC and Th subsets share overlapping developmental pathways and functions. Colored circles highlight transcripts expressed at least 2-fold higher in a single tonsillar subset compared with the other three subsets. Comparisons of fold change expression profiles revealed important features of lineage specification and functional polarization.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/scientists-discover-master-dimmer-switches-that-control-activity-of-immune-cells/
10.1534/genetics.116.197285,Biology_easy_151,"""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said.","Note that s e (t) is timedependent, as it is a function of the driver frequency.","Yet, faced with the new and sophisticated CRISPR/Cas9 method of gene drive, nature is still likely to fight back to resist the mutation successfully, Unckless said. ""We expect that resistance alleles will pop up either before the drive can spread, or after the drive spreads, and eventually replace the drive,"" he said. They show nature still has the edge over scientists hoping to solve human problems with GM organisms.","This 'effective' selection coefficient s e (t) specifies the expected change in frequency of the resistance allele in generation t under a model of exponential growth. Note that s e (t) is timedependent, as it is a function of the driver frequency. If resistance alleles carry a cost themselves, then s e (t) could initially be negative and turn positive only after the driver has reached a certain frequency in the population.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1038/s41467-018-07557-4,Biology_easy_152,"If those goals are not reached, the potential fallout could be more detrimental to Arctic communities.",The major advantage of the approach presented here is that hazard quantification can be conducted with any available infrastructure or population dataset (also using planned infrastructure and future population if suitable high-quality datasets and projections are available) and for any policy-relevant global warming scenario.,"Hjort and his colleagues said that these projections are fairly conservative, and that the risks will not be offset by reaching emissions targets set by the Paris Agreement. If those goals are not reached, the potential fallout could be more detrimental to Arctic communities. Read More: Melting Permafrost Reveals Gnarly 30,000-Year-Old Baby Horse

""In the majority of these cases, I do not think that people will have to move to another area (even if they are living in the high-hazard areas),"" Hjort told me in an email.","Moreover, we were able to quantify and show the magnitude of infrastructure at risk across the circumpolar permafrost domain. The major advantage of the approach presented here is that hazard quantification can be conducted with any available infrastructure or population dataset (also using planned infrastructure and future population if suitable high-quality datasets and projections are available) and for any policy-relevant global warming scenario. The forthcoming infrastructure risk assessments would significantly benefit from applicable processbased transient models of ground thermal regime and highresolution climate and ground-ice data.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37952323296&p=1pl&v=1&x=YZkcSHKHdqhjfYYiUvZ_gw
10.1016/j.cell.2013.08.004,Biology_easy_153,These drugs also might have broader therapeutic value for patients with mental health issues.,"Following in vitro Crtc silencing, induction of Per1 and other CREB-mediated genes is greatly attenuated.","The findings reveal a little bit more about how our internal clocks function. In addition, the research could pave the way for drugs that could bring bodies in tune with the solar cycle more quickly. These drugs also might have broader therapeutic value for patients with mental health issues.","Our data show both in vitro and in vivo that CRTC1 translocates to the nucleus after phase-shifting stimuli and acts as a coactivator of CREB-driven transcription of Sik1 and Per1. Following in vitro Crtc silencing, induction of Per1 and other CREB-mediated genes is greatly attenuated. Elevated Per1 aligns the transcriptional/translational-feedback loop to the zeitgeber stimulus .",[1],Biology,train,1.0,news,http://www.scienceworldreport.com/articles/9204/20130902/what-causes-jet-lag-internal-clock-slow-change-time.htm
10.1126/sciadv.aau1291,Biology_easy_154,"""The neurotransmitters used in this study have well-understood effects on cells, and cells already use them to communicate with each other.","Although this work is focused on epilepsy treatment, we anticipate that tailored engineering of the FIP platform will enable additional applications for electrophoretic drug delivery in neural interfacing and the treatment of neurological disorders.","""The advantage of [targeted] chemical delivery is that the effect on cells is very specific,"" Proctor said. ""The neurotransmitters used in this study have well-understood effects on cells, and cells already use them to communicate with each other. So, in a sense, we can communicate with cells in their native language.""","The FIP probe demonstrated the capability to detect, stop, and even completely prevent SLEs in an animal model by timely delivery of inhibitory neurotransmitters to the seizure source. Although this work is focused on epilepsy treatment, we anticipate that tailored engineering of the FIP platform will enable additional applications for electrophoretic drug delivery in neural interfacing and the treatment of neurological disorders. Selective UV exposure and development of the SU8 layer formed the walls of the microfluidic channel.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34950349292&p=1pl&v=1&x=ffMz4n5n4XLtDMruPZnsFg
10.1002/ece3.3060,Biology_easy_155,"""Practically, what this says is that landscape variables are not quite as important as the timing of the breeding season.""","Similarly, observed that the fall breeding A. opacum has stronger genetic differentiation than A. maculatum among the same ponds in Massachusetts.","""Even though some habitat features seemed to affect dispersal, we found that, for all four species, breeding season was a better predictor than habitat of the observed genetic differences,"" Burkhart says. ""Practically, what this says is that landscape variables are not quite as important as the timing of the breeding season."" For those concerned with managing salamander populations as a means of managing forests, the study serves as a reminder that not all salamander species are alike.","In Missouri, found that the fall breeding A. annulatum had higher levels of genetic differentiation than the spring breeding A. maculatum on the same landscape. Similarly, observed that the fall breeding A. opacum has stronger genetic differentiation than A. maculatum among the same ponds in Massachusetts. From an evolutionary standpoint, the observed differences in dispersal distances and genetic structure between fall breeding and spring breeding species may be a result of the trade-off between larval period length and size at metamorphosis .",[1],Biology,train,1.0,news,http://www.futurity.org/salamanders-breeding-1515412-2/
10.1111/1365-2656.12871,Biology_easy_157,"It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked.""",Infection dose is likely to play an important role for the progression of RHDV.,"Our study shows the first evidence that both viruses work in tandem to control rabbit population numbers. It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked."" ""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus.","Alternatively, lower abundance of virus-carrying flies may result in lower abundance of virus particles in the environment, which, in turn, may lead to low dose contraction. Infection dose is likely to play an important role for the progression of RHDV. If reasonably large proportions of susceptible individuals are only exposed to low dose infections, population-level infectioninduced mortality will be much less than the mortality rate linked to high dose infections during epidemics.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1038/s41467-018-05396-x,Biology_easy_159,"""Taken together, these characteristics give the crystalsome its superior staying power in the bloodstream,"" said Cheng, whose research group specializes in engineering molecules for intravenous drug delivery.",The ultra-long circulation time of the 7-day crystallized BCCs arises from the high crystallinity and uniform crystalline chain packing on the curved BCC shells which minimize defect formation in the crystals.,"""And a more direct intravenous delivery means that treatments are likely to be more effective."" ""Taken together, these characteristics give the crystalsome its superior staying power in the bloodstream,"" said Cheng, whose research group specializes in engineering molecules for intravenous drug delivery. The discovery provides a strategy for producing long-circulating nanomaterials, which could lead to a new class of polymer nanoparticle carriers for drug delivery and gene therapy, according to the researchers.","Combining all these results, we can conclude that there is a close correlation between the BCC crystallinity and the blood circulation time, shown in Fig. The ultra-long circulation time of the 7-day crystallized BCCs arises from the high crystallinity and uniform crystalline chain packing on the curved BCC shells which minimize defect formation in the crystals. In 3-day, 5-day crystallized BCCs and the previously reported polymersome cases, relatively poorly controlled crystals lead to defect-rich particles, which may be prone to disassembly under blood flow.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34695773224&p=1pl&v=1&x=CZmJaSw0Bgfp5D_SpZKWJQ
10.1016/j.mito.2018.08.001,Biology_easy_160,"The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego.","When caring for acute disruptions in health, the careful identification of the trigger, or cause of the problem, and the anatomical location of the defect, is an important part of good medical care.","The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego. A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first. When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors.","Reframing the pathogenesis of chronic illness in this way, as a systems problem that maintains disease, rather than focusing on remote trigger(s) that caused the initial injury, permits new research to focus on novel signaling therapies to unblock the healing cycle, and restore health when other approaches have failed. When caring for acute disruptions in health, the careful identification of the trigger, or cause of the problem, and the anatomical location of the defect, is an important part of good medical care. If healing is incomplete between injuries, more severe disease is produced.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37036494336&p=1pl&v=1&x=fSLbjdg9pAN1rFXsEu2RGA
10.1098/rsos.171474,Biology_easy_161,"For example the FBI report referenced above finds that while the 63 active shooters examined in the study couldn't be linked based on demographics alone:

62% of the shooters had a history of acting in an abusive, harassing, or oppressive way (e.g.","These topics provide promising avenues for inquiry and have direct implications for literature focused on antisocial behaviours such as bullying, trolling and griefing .","""There's actually no useful profile of a mass shooter,"" Randazzo said, ""but there's a lot we can look at in terms of behavior."" For example the FBI report referenced above finds that while the 63 active shooters examined in the study couldn't be linked based on demographics alone:

62% of the shooters had a history of acting in an abusive, harassing, or oppressive way (e.g. excessive bullying, workplace intimidation); 16% had engaged in intimate partner violence, and 11% had engaged in stalking-related conduct.","This is not to say that some mechanics and situations in gaming do not foment angry feelings or reactions in players such as feelings of incompetence , trash talking or competition . These topics provide promising avenues for inquiry and have direct implications for literature focused on antisocial behaviours such as bullying, trolling and griefing . Instead, we argue that mere exposure to, and enactment of, putatively violent virtual acts in gaming contexts in aggregate is unlikely, on its own, to bear positively on perceivable differences in adolescents' aggression in real-world settings.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39882736616&p=1pl&v=1&x=QLA1HMQhScCizGL1drmq5A
10.1038/s41467-018-04627-5,Biology_easy_163,"For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors.",Widespread changes in the white matter track learning.,"In the majority of these subjects, diffusion rates decreased in the arcuate and inferior longitudinal fasciculus. For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors. The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said.","Motion and Reading Skill were unrelated (r(97) = 0.13, p = 0.19). Widespread changes in the white matter track learning. The AF and ILF connect distinct components of the reading circuitry and are thought to carry signals that contribute uniquely to the reading process 48 .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1098/rsos.171474,Biology_easy_164,There's also no evidence that either the El Paso or Dayton shooter was a fan of video games.,"Alternatively, youngsters who are willing to report in less desirable ways might be more likely to report on both their own and in-game aggression.","""So we found pretty convincing evidence that it didn't really matter what kinds of games teenagers played, boys and girls, violent games, nonviolent games -- that wasn't really a useful piece of information about whether or not a parent saw aggressive behaviors in their young person."" There's also no evidence that either the El Paso or Dayton shooter was a fan of video games. In fact, the majority of people with mental health problems are not more likely to be violent.","For example, it may be that more aggressive young people tend to rate the games they play as having more aggression because underlying differences in aggressive or hostile perceptual biases orient them to these game features, whereas less aggressive young people attend to different aspects of play. Alternatively, youngsters who are willing to report in less desirable ways might be more likely to report on both their own and in-game aggression. Second, our review of the literature made it clear that there is a high level of methodological flexibility in the ways that aggression outcomes and violent gaming are assessed .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39881272230&p=1pl&v=1&x=agjUuQHKttCmyqc0lNUvPA
10.1038/s41467-019-09863-x,Biology_easy_165,"This is at pre-industrial levels, which is consistent with international Paris Agreement target.","5a ; even with the current parameterisations, the upper tails in the distributions are at their lowest for the 1.5°C scenario.","However, the interdisciplinary team behind the research notes that if the world keeps the global temperature rise limited to 1.5 degrees Celsius, the additional economic impact drops to $25 trillion. This is at pre-industrial levels, which is consistent with international Paris Agreement target. ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C,"" explained Dmitry Yumashev, lead author from the Pentland Centre for Sustainability in Business at Lancaster University.","Some of these effects are already included implicitly in the highly uncertain non-economic and discontinuity impact sectors in PAGE-ICE, contributing to the long upper tails in the distributions of the total economic effect of climate change in Fig. 5a ; even with the current parameterisations, the upper tails in the distributions are at their lowest for the 1.5°C scenario. It is possible that with an explicit modelling of the other climatic and societal tipping elements, as well as with comprehensive representation of the impacts of rising temperatures and increasing extreme weather events on economic growth 63 , both the economic effect of climate change with legacy Arctic feedbacks, and the additional impacts due to the nonlinear PCF and SAF, would be higher compared to those reported here.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39064299256&p=1pl&v=1&x=uiRMkpkYPuCChqjw9RPdQw
10.1016/j.cmet.2015.02.003,Biology_easy_166,"""Chronic accumulation of salt in the tissue thus may have become rather a problem than an advantage,"" Titze says.","Similarly, HS augmented NO release in peritoneal MF ( Figure S1A ).","However, with the development of effective antibiotics and other infection treatments for infection, humans may no longer need huge amounts of salt in their system to protect them, the researchers note. ""Chronic accumulation of salt in the tissue thus may have become rather a problem than an advantage,"" Titze says. Therefore, the researchers caution, their findings should in no way be taken as a recommendation of a high salt diet as beneficial for health.","Parallel experiments with increased concentrations of the tonicity control, urea, (Table S1 ) neither increased Nos2 expression nor NO release ( Figure 2A ). Similarly, HS augmented NO release in peritoneal MF ( Figure S1A ). In line with earlier data , HS boosted LPS-induced TNF secretion in MF (Figures S1B and S1C).",[1],Biology,train,1.0,news,http://www.techtimes.com/articles/37351/20150304/the-healthy-side-to-sodium.htm
10.1086/693564,Biology_easy_168,"""It is just mean to the creature,"" Kammerer said.","We readily acknowledge that the free-living biodiversity of soils may also be extensive, and its inclusion might change our estimates somewhat.","Nearly 15 years later, the money from the auction is still being used for conservation in the region. ""It is just mean to the creature,"" Kammerer said. ""I think all animals, all organisms, are precious and irreplaceable and worthy of respect.""","Second, in some groups we did not include estimates of their free-living diversity, especially in soils (e.g., mites, nematodes, protists, and bacteria). We readily acknowledge that the free-living biodiversity of soils may also be extensive, and its inclusion might change our estimates somewhat. However, additions of a few million species, as for soil fungi , would have little impact on our main results (Table 1) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38981580573&p=1pl&v=1&x=Y8hj7JQLdrpGIg7lpFM9kg
10.1373/clinchem.2012.187617,Biology_easy_169,"According to the scientists involved, this was an unprecedented and unique opportunity to find out if long-term space travel is safe, or even possible.","Combinations of metabolomics strategies, including MS, HPLC, and NMR, are leading to discoveries of metabolites and small compounds derived from the human microbiome.","""But that does not replicate what's going on in the mammalian gut,"" Vitaterna said. According to the scientists involved, this was an unprecedented and unique opportunity to find out if long-term space travel is safe, or even possible. But the science can't stop here.","Thus, modulation of murine metabolic homeostasis can be achieved by altering the gut microbiota through antibiotic manipulation. Combinations of metabolomics strategies, including MS, HPLC, and NMR, are leading to discoveries of metabolites and small compounds derived from the human microbiome. One such microbial signal and biogenic amine, histamine, was identified and quantified in TNF-inhibitory HILIC-HPLC fractions derived from Lactobacillus reuteri found in breast milk and the gut .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.14814/phy2.13617,Biology_easy_170,"""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said.","The intra and interassay coefficients of variation were 4.1% and 6.6%, respectively.","For preschoolers, this may not only lead to trouble falling asleep one night, but to chronic problems feeling sleepy at bedtime. ""The effects of light at night exposure can definitely go beyond sleep,"" Akacem said. The study sample size was small and it used only one intensity of light, 1,000 lux, which is far greater than the intensity of a typical handheld electronic device, she notes.","For one child, we replaced actigraphic measures with sleep diary data due to noncompliance with wearing the actigraph. The intra and interassay coefficients of variation were 4.1% and 6.6%, respectively. Children were exposed to an average of 1033 AE 158 lux during the experimental light stimulus.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33480456707&p=1pl&v=1&x=hN9hUXXld--gBVhWbWCNfA
10.1086/693564,Biology_easy_171,"Chakrabarty said auctions that result in a species being named after someone not involved in the work can be ""abhorrent to the culture of science"" and argues that there are other ways to get funding for field work.","Therefore, the proportional richness of nematodes (relative to other organisms) may depend on how many groups of insects are potentially infected by nematodes, the number of nematode parasites per insect species, and their level of host specificity.","It seems like a pittance,"" Kammerer said. Chakrabarty said auctions that result in a species being named after someone not involved in the work can be ""abhorrent to the culture of science"" and argues that there are other ways to get funding for field work. ""It was an opportunity to bring attention to an amazing place, because we saw this primate primarily in and adjacent to Madidi National Park,'' Wallace said.","This yields 10.2 million mite species, and 51 million arthropod species overall. Therefore, the proportional richness of nematodes (relative to other organisms) may depend on how many groups of insects are potentially infected by nematodes, the number of nematode parasites per insect species, and their level of host specificity. They also noted that each fig species appeared to contain two unique nematode species in their fruits, which appear to be related to fig wasps.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38981580573&p=1pl&v=1&x=Y8hj7JQLdrpGIg7lpFM9kg
10.1373/clinchem.2012.187617,Biology_easy_173,"Overall, NASA views this study as good news so far for their plans of crewed missions to Mars.","In another study, TLR2-deficient mice developed obesity, insulin resistance, and glucose intolerance, and the gut microbiomes of TLR2-deficient mice had a greater abundance of Firmicutes and fewer Actinobacteria of the genus Bifidobacterium .","One of his eyeballs swelled slightly and his telomeres, special caps on the ends of his DNA strands, also experienced long-term shortening upon return to Earth -- both are phenomena seen generally among space station astronauts. Overall, NASA views this study as good news so far for their plans of crewed missions to Mars. While a flight to Mars will expose astronauts to more radiation and longer durations of space flight, the researchers said this study is one indication that the flight itself isn't likely to permanently harm human bodies.","When gut microbiomes from these mice were transplanted into germ-free mice with an intact tolllike receptor 5 (TLR5) gene, recipient mice developed similar features of the metabolic syndrome, which suggests that the intestinal microbiome was the key determinant of this disease phenotype. In another study, TLR2-deficient mice developed obesity, insulin resistance, and glucose intolerance, and the gut microbiomes of TLR2-deficient mice had a greater abundance of Firmicutes and fewer Actinobacteria of the genus Bifidobacterium . Administration of an antibiotic cocktail eliminated many of the Firmicutes and resulted in improved insulin activity and glucose tolerance.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1016/j.cmet.2015.02.003,Biology_easy_174,MORE FDA Wants to Limit Your Salt Intake.,"Additional 23 Na spectroscopy revealed enhanced Na + concentrations in infected human skin ( Figure 1B ), which were consistent with Na + -to-water ratios obtained by chemical analysis in bitten mice with infected skin lesions ( Figures 1C  and 1D ).","So I would be hesitant to draw any conclusions for humans at this stage."" He and others are already setting up more experiments, however, to study how salt might become the next weapon in fighting infections. MORE FDA Wants to Limit Your Salt Intake.","Na MRI reliably detects skin-Na + content but underestimates Na + concentrations. Additional 23 Na spectroscopy revealed enhanced Na + concentrations in infected human skin ( Figure 1B ), which were consistent with Na + -to-water ratios obtained by chemical analysis in bitten mice with infected skin lesions ( Figures 1C  and 1D ). Infected mouse skin displayed $40 mmol/l increase in (Na + +K + )-to-water ratio, compared to plasma levels ( Figure 1D ).",[1],Biology,train,1.0,news,http://time.com/3730061/the-weird-benefit-of-eating-salty-food/
10.1038/s41467-018-04906-1,Biology_easy_175,Note: material may have been edited for length and content.,This enabled the fine patterns of transparent electrodes required in fingerprint sensors that need to detect the period between the ridges and valleys of human fingers (~100 μm) .,"This suggests that the sensors may have the potential to replace finger-print activation buttons in the future. Note: material may have been edited for length and content. For further information, please contact the cited source.","On the other hand, the AgNF-AgNW hybrid structure exhibited a negligible dependence of R s on the pattern widths, and it had a significantly low R s even for narrow patterns with widths <100 μm. This enabled the fine patterns of transparent electrodes required in fingerprint sensors that need to detect the period between the ridges and valleys of human fingers (~100 μm) . Figure 2f shows the relative change in resistance of the AgNF-AgNW hybrid electrode that was formed on a c-PI film (thickness: 25 μm) as a function of the radius of curvature and the corresponding bending-induced strain (ε).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34462398193&p=1pl&v=1&x=A28oMFBmBg6QkN0nivavQw
10.1038/s41467-018-05870-6,Biology_easy_176,"Novel Science

The scientists caution the research is early stage.","6a ), several MD-miRNAs were highly induced in the liver of L-Ago2 WT mice fed HFD and a leptin-deficient (ob/ob) obese mice ( Fig.","""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases."" Novel Science

The scientists caution the research is early stage. Their findings still need additional study and verification in laboratory models and the development of a practical therapeutic to inhibit Ago2 in a clinical setting for patients.","While Ago2 protein levels were slightly decreased in the liver of mice fed HFD (Supplemental Fig. 6a ), several MD-miRNAs were highly induced in the liver of L-Ago2 WT mice fed HFD and a leptin-deficient (ob/ob) obese mice ( Fig. 6c and Supplemental Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37060860200&p=1pl&v=1&x=8Lal0RIMgLlUZpQnXZ6jPQ
10.1242/jeb.147082,Biology_easy_177,"Perhaps rat snakes were ""just terrible"" at escaping once kingsnakes had them in their grasp, Penning reasoned.","In a full model (pulling force=mass×species), the interaction (F 5,86 =0.25, P>0.9) and species factor (F 5,86 =2.1, P>0.068) were not significant.","But, after hours of complex dissection, ""Lo and behold, there was no quantifiable difference,"" Penning said. Perhaps rat snakes were ""just terrible"" at escaping once kingsnakes had them in their grasp, Penning reasoned. But that experiment also failed to find a difference.","Maximum pulling forces ranged from 0.9 to 24.5 N (Table 3) . In a full model (pulling force=mass×species), the interaction (F 5,86 =0.25, P>0.9) and species factor (F 5,86 =2.1, P>0.068) were not significant. Removing the interaction term did not result in a significant species effect, producing a final model that included only pulling force and mass.",[1],Biology,train,1.0,news,http://www.livescience.com/58285-how-kingsnakes-eat-rat-snakes.html
10.1038/s41467-019-09863-x,Biology_easy_179,"""We hope our work will lead to further assessments of multiple nonlinear processes in the Earth's climate system, both those associated with the Arctic and beyond.""","CMIP5 GCMs, however, produced increases in the water vapour feedback in warmer climates associated with rising tropopause 57 .","The research team say they hope their assessments will provide a better understanding of the socio-economic risks from climate change under different scenarios, and help guide policy-makers towards prudent decisions on emissions reduction targets. ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C,"" Yumashev said. ""We hope our work will lead to further assessments of multiple nonlinear processes in the Earth's climate system, both those associated with the Arctic and beyond.""","The combined magnitude of these feedbacks showed weak responses to GMST increases in CMIP3 GCMs 21 . CMIP5 GCMs, however, produced increases in the water vapour feedback in warmer climates associated with rising tropopause 57 . While the state-dependencies in the planetary feedbacks require further investigations as part of CMIP6, the evidence so far suggests that apart from the SAF effects presented here, the magnitudes of the feedbacks are less likely to decrease with GMST.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39075144927&p=1pl&v=1&x=7hu8D2B6RjJADdTPIfJdLQ
10.1098/rstb.2008.0288,Biology_easy_181,Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks.,"However, we would argue that the potential costs of expertise also warrant consideration.","With the new research, scientists can definitively say that London taxi drivers not only have larger-than-average memory centers in their brains, but also that their intensive training is responsible for the growth. Researchers noticed that a part of the brain called the hippocampus was much larger in these animals than in similar species that did not secret away their snacks. In other words, taxi drivers had plumper memory centers than their peers.","This was attributed to their musical sight-reading and motor sequencing expertise. However, we would argue that the potential costs of expertise also warrant consideration. We found that the hippocampus is not required for general orientation in the city, detailed topographical knowledge of landmarks and their spatial relationships, or even for the navigation along some routes, all of which abilities were preserved.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1016/j.cell.2018.06.045,Biology_easy_182,The researchers were also able to show that the babies who had abnormal development of the gut flora during the first weeks also demonstrated a disorder of the immune system.,The finding that children of different levels of maturity and postnatal environmental conditions converge on a shared developmental trajectory early in life was unexpected to us.,"Only small amounts of blood, just a few drops from each baby, are needed to analyse all the white blood cells and hundreds of proteins circulating in the blood. The researchers were also able to show that the babies who had abnormal development of the gut flora during the first weeks also demonstrated a disorder of the immune system. ""Our results are important for better understanding the infection-sensitivity of newborn babies and the risks of premature birth,"" says Dr Brodin.","We conclude from these findings that interactions with microbes colonizing newborn children during the first weeks of life are seemingly important, and perturbation to this process of colonization is associated with perturbations to the stereotypic immune system developmental early in life. The finding that children of different levels of maturity and postnatal environmental conditions converge on a shared developmental trajectory early in life was unexpected to us. At the same time, gut microbiome composition differed between children, and the likelihood of shared exposures across such a diverse group of children seems unlikely.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34901466233&p=1pl&v=1&x=3s65PefAzHVGUtcPhREU_Q
10.3892/ijmm.2011.724,Biology_easy_183,"Stock up on various waters, bananas, eggs and magnesium, and you'll be back to your old self in no time.",The concentration of sugar is considerably lower than that found in the sap of sugar maples.,"Organic bananas, of course, contain more beneficial potassium and other minerals."" Stock up on various waters, bananas, eggs and magnesium, and you'll be back to your old self in no time. Of course, whether you try one or all of the above remedies, there's one tip that will help your hangover the most: Skip the eggnog altogether or drink in moderation.","Thus, the severity of liver disease can be proportional to the down-regulation of the activity of ADH or ALDH. The concentration of sugar is considerably lower than that found in the sap of sugar maples. The best sap production comes from cold-winter areas with continental climates.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38074943064&p=1pl&v=1&x=2b4yyZTVq7IsxuRn7mTrKw
10.1038/jid.2009.93,Biology_easy_185,Diverse onderzoeken hebben aangetoond dat het aanbrengen van kokosolie op de huid hydraterend werkt.,"Our data demonstrate that either intradermal or epicutaneous administration of lauric acid with P. acnes decreased the number of detected bacteria in the ear, thereby relieving P. acnes-induced ear swelling and granulomatous inflammation ( Figures 5 and 6 ).","Maar volgens een onderzoek is laurinezuur effectiever tegen acne dan benzoylperoxide. Diverse onderzoeken hebben aangetoond dat het aanbrengen van kokosolie op de huid hydraterend werkt. Vette huid

Heb je een vette huid dan kun je beter uitkijken met kokosolie op je gezicht smeren.","However, P. acnes inside cells may be susceptible to the antimicrobial activities of lauric acid, which is cell membrane permeable. Our data demonstrate that either intradermal or epicutaneous administration of lauric acid with P. acnes decreased the number of detected bacteria in the ear, thereby relieving P. acnes-induced ear swelling and granulomatous inflammation ( Figures 5 and 6 ). In addition, application of lauric acid did not trigger the skin cells to undergo apoptosis (Figures 6 and Figure S4 ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38348114665&p=1pl&v=1&x=C9tpqKEjjKmmVRf7LIFKlg
10.1098/rsos.171474,Biology_easy_186,"""They might think Fortnite is violent or that people who play Mario are more likely to be aggressive towards turtles.",A total of 1596 games were named and successfully coded for violent content.,"He found that people who have never played video games before are more likely to have biases about them and unrealistic expectations about them. ""They might think Fortnite is violent or that people who play Mario are more likely to be aggressive towards turtles. But once you get the hands-on experience, you see that this is a pretty silly idea.""","Individuals' scores on the five-item conduct problems subscale of the SDQ ranged from 5 to 15 A total of 1596 games were named and successfully coded for violent content. Of these nearly two in three had a violent content badge and were coded 1 (k ¼ 1033), while the remaining games did not have a violent content badge and were coded zero 0 (k ¼ 560).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39882021759&p=1pl&v=1&x=WDSVA9_GGY2tcF2kX9kO8w
10.1038/s41467-018-04408-0,Biology_easy_187,"The study, published in Nature Communications, can be of significance for the future treatment of diseases.","By contrast, the number of dendritic cells, macrophages/monocytes and neutrophils were unaltered in G-ARKO spleens (Supplementary Fig.","New findings are now being presented on possible mechanisms behind gender differences in the occurrence of rheumatism and other autoimmune diseases. The study, published in Nature Communications, can be of significance for the future treatment of diseases. ""In this way, we can eventually provide better treatment for the diseases.""","Male G-ARKO mice had 1.8-fold more B cells in the spleen than littermate controls (with the Pgk1-Cre construct only) ( Fig. By contrast, the number of dendritic cells, macrophages/monocytes and neutrophils were unaltered in G-ARKO spleens (Supplementary Fig. G-ARKO mice are also testosterone-deficient .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34228585539&p=1pl&v=1&x=jeRWiJSUImhYEA135bTOfw
10.1038/ncomms14514,Biology_easy_188,"It turns out with these clusters, every single cluster is exactly the same structure.","This mode hardening indicates the presence of a compressive strain in the NCs, which increases in magnitude with decreasing size.","This crystal structure is a result of internal strain in the clusters. It turns out with these clusters, every single cluster is exactly the same structure. Somehow, at this size, the electronic structure of the material is so stable that every single cluster has the same arrangement of atoms.""","5) . This mode hardening indicates the presence of a compressive strain in the NCs, which increases in magnitude with decreasing size. It must, however, be acknowledged that the LO phonon frequency can shift also due to the effect of phonon confinement in small crystallites, as shown by the classic work of Richter et al.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uNVFlIGRBVk/
10.1080/10635150701775111,Biology_easy_190,"And that under normal circumstances when they were very few in number they were able to recover.""",56 FIGURE 2.,"""Given the genetic history, it is clear that the pigeon numbers got really big and then really small. And that under normal circumstances when they were very few in number they were able to recover."" Early, too, feels that the paper leads to ""a hypothesis rather than a strong conclusion.""",In cases of divergent ecological niches and a pair of valid 910 SYSTEMATIC BIOLOGY VOL. 56 FIGURE 2. The disjunct northern area highlighted by the ellipse is actually not occupied by Phelsuma modesta.,[1],Biology,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1016/j.neuron.2014.05.028,Biology_easy_191,"""PTSD is unique among psychiatric disorders in that we know when it starts -- at the time of the trauma.",*p % 0.05 versus HC and 2 hr.,"The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder). ""PTSD is unique among psychiatric disorders in that we know when it starts -- at the time of the trauma. Out of thousands of genes they examined, their ""top gene"" was Tachykinin 2 or Tac2.",False discovery rate (FDR) was (B) Tac2 mRNA levels are rapidly upregulated in the amygdala during fear consolidation 30 min after fear conditioning. *p % 0.05 versus HC and 2 hr. n = 7-8 per group.,[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-05870-6,Biology_easy_192,"""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology.",Inactivation of hepatic Ago2 improves systemic glucose metabolism.,"This helped stave off obesity and prevented the mice from developing diabetes and fatty liver disease, which can severely damage the vital organ--which helps rid the body of toxic substances. ""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology. ""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases.""","These results suggest a possible association of Ago2 and miRNAs whose expression is regulated by Ago2 with human metabolic diseases. Inactivation of hepatic Ago2 improves systemic glucose metabolism. We observed that L-Ago2 KO mice fed normal chow diet (NCD) exhibited enhanced capacities for glucose metabolism, as assessed by glucose, insulin, and pyruvate tolerance tests (GTT, ITT, and PTT) after 20 weeks of age ( Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37061323146&p=1pl&v=1&x=l5-40ws2AOkos3TN_hE55A
10.1016/j.mito.2018.08.001,Biology_easy_193,"Naviaux suggests science may be on the cusp of writing a second book of medicine, one that focuses on the prevention of chronic illness and new treatments for chronic disease that can help some people recover completely, where old approaches produced only small improvements with symptoms that persisted for life.","The temporal parallel between disease, diet, and exercise is no accident.","""It's abnormalities in metabokine signaling that cause the normal stages of the cell danger response to persist abnormally, creating blocks in the healing cycle,"" said Navaiux, who noted CDR theory also explains why some people heal more quickly than others and why a chronic disease seemingly treated successfully can relapse. Naviaux suggests science may be on the cusp of writing a second book of medicine, one that focuses on the prevention of chronic illness and new treatments for chronic disease that can help some people recover completely, where old approaches produced only small improvements with symptoms that persisted for life. ""New treatments might only be given for a short period of time to promote healing, not unlike applying a cast to promote the healing of a broken leg.","The tempo of chronic disease is slower than many people might think. The temporal parallel between disease, diet, and exercise is no accident. The ability to shift metabolism according to seasonal changes and new patterns of food availability within a few weeks of migration to a new location was key to the survival of our ancestors.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37052707703&p=1pl&v=1&x=sh4bblHfq4G8CThdM37YaA
10.1098/rsos.171474,Biology_easy_194,"An important step taken in this study was preregistration, where the researchers publicly registered their hypothesis, methods and analysis technique prior to beginning the research.","The results provide confirmatory evidence that violent video game engagement, on balance, is not associated with observable variability in adolescents' aggressive behaviour.","""Our findings suggest that researcher biases might have influenced previous studies on this topic, and have distorted our understanding of the effects of video games,"" says co-author Dr. Netta Weinstein from Cardiff University. An important step taken in this study was preregistration, where the researchers publicly registered their hypothesis, methods and analysis technique prior to beginning the research. A cherry-picked result can add undue weight to the moral panic surrounding video games.","This is among the first studies to test the effects of violent gaming on human aggression using a preregistered hypothesis-testing framework and the first to do so following the registered reports protocol. The results provide confirmatory evidence that violent video game engagement, on balance, is not associated with observable variability in adolescents' aggressive behaviour. A healthy ecosystem of exploratory and registered research reports will enable scientists to conduct metanalytic research to evaluate the inferences drawn from these methodologies.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38630667262&p=1pl&v=1&x=eg7bkQTzSVqLm5ru549FjQ
10.1016/j.mito.2018.08.001,Biology_easy_195,"""It's abnormalities in metabokine signaling that cause the normal stages of the cell danger response to persist abnormally, creating blocks in the healing cycle,"" said Navaiux, who noted CDR theory also explains why some people heal more quickly than others and why a chronic disease seemingly treated successfully can relapse.",Over 100 chronic illnesses can be classified according to the stage of the CDR that is blocked (Table 1) .,"Naviaux's team is preparing for a larger, longer trial in 2019. ""It's abnormalities in metabokine signaling that cause the normal stages of the cell danger response to persist abnormally, creating blocks in the healing cycle,"" said Navaiux, who noted CDR theory also explains why some people heal more quickly than others and why a chronic disease seemingly treated successfully can relapse. Naviaux suggests science may be on the cusp of writing a second book of medicine, one that focuses on the prevention of chronic illness and new treatments for chronic disease that can help some people recover completely, where old approaches produced only small improvements with symptoms that persisted for life.","The savings in a single year would be more than the annual budgets of the National Institutes of Health (NIH; $37 billion), Environmental Protection Agency (EPA; $8.7 billion), Food and Drug Administration (FDA; $5.1 billion), and the US Department of Agriculture (USDA; $151 billion) combined. Over 100 chronic illnesses can be classified according to the stage of the CDR that is blocked (Table 1) . Metabolic addiction to the chemistry produced by different stages of the CDR can occur.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ypj94azpXWE/
10.1098/rstb.2004.1522,Biology_easy_196,It really took a village to care for my sick sister.,This changing sample from one wave to the next seriously limits our ability to analyse the dynamics of subjective well-being.,"""When Ruthie got sick, there were things that her family could not do--they couldn't get the kids to school without help, they couldn't get meals on the table without help, they couldn't pay the bill without help. It really took a village to care for my sick sister. Hundreds of people came together, raising $43,000 for their friend.","The number of transition and developing countries increases from one wave to the next, and many of the industrial countries sampled in the first wave are absent for at least one of the two following waves. This changing sample from one wave to the next seriously limits our ability to analyse the dynamics of subjective well-being. Although this means that the sample does not exactly match national characteristics, the very large size provides a great deal of power, and many tests suggest that the results can in most respects be treated as nationally representative.",[1],Biology,train,1.0,news,http://www.theatlantic.com/health/archive/2013/04/relationships-are-more-important-than-ambition/275025/
10.1080/10635150701775111,Biology_easy_197,"It is nature's fault too

Zink and his colleagues thought natural fluctuation may have played a role in the bird's extinction.","There is no obvious sexual dichromatism and no sexual dimorphism, except that males have femoral pores and may reach a slightly larger size (see Table 2 ).","Their excrement was toxic to plants and when a flock roosted on trees, they could break all the branches through the sheer numbers perching."" It is nature's fault too

Zink and his colleagues thought natural fluctuation may have played a role in the bird's extinction. They knew that such fluctuations could dramatically reduce population size, and perhaps human exploitation through hunting and trade may have tipped the balance at the wrong time for this species, which could never recover.","The only ontogenetic variation in coloration now seen 919 in preservation is the slightly pale yellow tail, which is found in the juvenile coloration of smallest specimen examined, AMNH R-155722 (RAX 8682), with an SVL of 25 mm. There is no obvious sexual dichromatism and no sexual dimorphism, except that males have femoral pores and may reach a slightly larger size (see Table 2 ). nov. were seen on the trunks or frond stems of Traveller's Palms (Ravenala madagascariensis) growing in plantations, grassland, or gardens around and within the town of Mananjary (0 to 20 m elevation).",[1],Biology,train,1.0,news,http://www.theepochtimes.com/n3/753700-humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1080/10635150701775111,Biology_easy_199,"When asked what could be done to gather more evidence to support their hypothesis, Zink admitted that the fluctuation hypothesis is part speculation.",nov. model (Fig.,"It shows our method is pretty robust."" When asked what could be done to gather more evidence to support their hypothesis, Zink admitted that the fluctuation hypothesis is part speculation. ""Given the genetic history, it is clear that the pigeon numbers got really big and then really small.","In contrast to the combined Phelsuma dubia + P. hielscheri + P. ravenala sp. nov. model (Fig. 5f ), the majority of Phelsuma dubia + P. ravenala sp.",[1],Biology,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1086/693564,Biology_easy_200,"The most valuable animal turned out to be a wormlike amphibian from Panama, which drew a winning bid of $25,000 from a British sustainable building materials company called EnviroBuild.","September 2017 235 lower than host richness, based on declining parasite description rates over time .","The Virginia-based nonprofit group claimed the auction raised $182,500 for its conservation programs. The most valuable animal turned out to be a wormlike amphibian from Panama, which drew a winning bid of $25,000 from a British sustainable building materials company called EnviroBuild. With more than 27,000 species at risk of extinction, auctioning off naming rights seems like a fairly harmless way to increase public awareness and raise much-needed funding for conservation efforts.","Our approach is only one among many used to estimate global richness (e.g., . September 2017 235 lower than host richness, based on declining parasite description rates over time . We suggest that the most important parasites for estimating overall global richness are those with potentially species-specific host relationships in the most diverse insect orders (e.g., bacteria, mites, nematodes, apicomplexans, microsporidians).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38981580573&p=1pl&v=1&x=Y8hj7JQLdrpGIg7lpFM9kg
10.1016/j.neuron.2018.12.026,Biology_easy_201,"He found, however, that even though the ratio of excitation to inhibition was higher than in normal mouse brains, neurons maintained a normal spiking rate.","Averaging across WT cells revealed a smooth contour of G ex /G in scaling combinations that predict no change in PSP peak (PSP diff = 0), which we term the ''PSP stability contour'' ( Figure 3D , thick contour).","In all the mice, inhibition was lower than normal, and excitation was also lower, though less so, leading to an increase in the excitation-inhibition ratio. He found, however, that even though the ratio of excitation to inhibition was higher than in normal mouse brains, neurons maintained a normal spiking rate. This was because the changes in inhibition and excitation were precisely coordinated to offset each other.","Instead, equal weakening of G ex and G in reduces PSP peak, and further weakening of G in restores it (example cell, Figure 3C ). Averaging across WT cells revealed a smooth contour of G ex /G in scaling combinations that predict no change in PSP peak (PSP diff = 0), which we term the ''PSP stability contour'' ( Figure 3D , thick contour). This contour is (D) Contour plot of mean predicted change in overall PSP peak for different combinations of Gex and Gin scaling, for all Cntnap2 +/+ cells.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.2337/db13-1600,Biology_easy_202,"Far-reaching consequences

Casey Donovan, MaryAnn Bohland-Matveyenko, Anne Jokiaho and Alan Watts

For the past seven years, Donovan and USC Dornsife neuroscientist Alan Watts collaborated on research into the central or physiological mechanisms that are important in normalizing blood glucose levels.","Finally, we demonstrated that both hindbrain neuronal activation and the sympathoadrenal response to rapid-onset hypoglycemia (20.16 mmol/L/min) appear independent of peripheral glucosensory input.","""And unlike hyperglycemia or diabetes, which take many years to become lethal, the severe complications of deep hypoglycemia can develop within hours."" Far-reaching consequences

Casey Donovan, MaryAnn Bohland-Matveyenko, Anne Jokiaho and Alan Watts

For the past seven years, Donovan and USC Dornsife neuroscientist Alan Watts collaborated on research into the central or physiological mechanisms that are important in normalizing blood glucose levels. Each of their findings, which could have far-reaching consequences for the development of insulin therapies for Type 1 and Type 2 diabetes, is presented in two papers published together online on April 11 and 16 in the journal Diabetes.","Thus, as has been shown for the sympathoadrenal response, the ascending trajectory used for portal-mesenteric hypoglycemic sensory information to the hindbrain appears to be spinal, not vagal. Finally, we demonstrated that both hindbrain neuronal activation and the sympathoadrenal response to rapid-onset hypoglycemia (20.16 mmol/L/min) appear independent of peripheral glucosensory input. These data provide compelling evidence that a functional PMV-hindbrainsympathoadrenal network is required for CRRs to slowonset hypoglycemia.",[1],Biology,train,1.0,news,http://www.healthcanal.com/metabolic-problems/diabetes/49962-diabetes-detectives.html
10.1016/j.neuron.2017.06.028,Biology_easy_203,"When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London.","Although both Bcan isoforms seem to be regulated by activity, the increase in the Bcan1/Bcan2 ratio suggests that Bcan2 may be the main isoform that responds to changes in activity ( Figure S7P ).","These novel findings show that Brevican is dynamically regulated by experiences coming from the environment and is fundamentally required for spatial working memory and short-term memories. When we identified some of the mechanisms underlying this regulation, I was amazed by how a single protein can act as an activity sensor, orchestrate such a complex molecular program and simultaneously influence several key cellular processes', said Dr Emilia Favuzzi, first author of the study from the Centre for Developmental Neurobiology (CDN) at King's College London. We think that the identification of the relevant molecular mediators of this form of plasticity may offer novel therapeutic strategies to recover from deficits in perception, learning and memory associated with a range of diseases.'","Noteably, the reduction of Bcan2-but not Bcan1-was still maintained after 30 days of EE ( Figures 7N, 7O , S7N, and S7O). Although both Bcan isoforms seem to be regulated by activity, the increase in the Bcan1/Bcan2 ratio suggests that Bcan2 may be the main isoform that responds to changes in activity ( Figure S7P ). Altogether, these experiments demonstrate that BCAN levels are dynamically regulated by activity under physiological conditions.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/how-neurons-sense-our-everyday-life/
10.1038/ncomms4999,Biology_easy_204,"Any longer and the enzyme would simple oscillate forever: react, unreact, react, unreact, etc.",The dramatically improved signal-to-noise ratio hence allows the reliable detection of small changes induced by biochemical means.,"Any shorter, and biochemical reactions would become inefficient as energy is drained from the system too quickly. Any longer and the enzyme would simple oscillate forever: react, unreact, react, unreact, etc. The picosecond ringing time is just perfect for the most efficient reaction.","This advantage means that small changes in a particular spectral region, which might appear as a simple amplitude change when observed within a narrow frequency range, can be identified and interpreted correctly. The dramatically improved signal-to-noise ratio hence allows the reliable detection of small changes induced by biochemical means. In the OKE spectra of lysozyme solutions, we identify a terahertz-frequency underdamped delocalized vibrational mode that blue shifts and increases in intensity upon binding of NAG 3 .",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140603092424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/infdis/jiw306,Biology_easy_205,The suppression of PPAR-g and GLUT-1 levels in mouse models of bacterial meningitis caused extensive neurological effects.,"This glucose-deficient environment leads to a stress response in the BBB, thereby further enhancing the expression of Ecgp96 for more bacteria to bind and invade.","""We found that expression of glucose transporters is completely shut down by bacteria, leaving insufficient fuel for the immune cells to fight off the infection,"" said the study's first author, Subramanian Krishnan, PhD, of the Division of Infectious Diseases at CHLA. The suppression of PPAR-g and GLUT-1 levels in mouse models of bacterial meningitis caused extensive neurological effects. The researchers showed that a two-day treatment regimen with partial or selective PPAR-g agonists (Telmisartan and Rosiglitazone -- both FDA-approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.","downregulation of GLUT-1 expression. This glucose-deficient environment leads to a stress response in the BBB, thereby further enhancing the expression of Ecgp96 for more bacteria to bind and invade. On the contrary, we demonstrated here that E. coli K1 suppresses PPAR-γ and GLUT-1 levels in the endothelial cells forming the BBB and that upregulation of PPAR-γ (using partial and selective PPAR-γ agonists) prevented E. coli K1 translocation of the BBB to establish infection.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5mIb8JRncoY/
10.1038/s41467-018-06108-1,Biology_easy_206,"Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions.","In contrast to the majority of the previously studied plant species including A. thaliana, we found significantly positive values of α for the two diploid species and both allopolyploid subgenomes.","With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex. Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions. ""With these results, we have demonstrated on a molecular-genetic level that genome duplications can positively affect the adaptability of organisms,"" says plant scientist Timothy Paape.","outcrossing ancestral species with greater N e have fewer neutral mutations and higher proportions of deleterious mutations than their derived, self-fertilized subgenomes. In contrast to the majority of the previously studied plant species including A. thaliana, we found significantly positive values of α for the two diploid species and both allopolyploid subgenomes. The diploid species A. halleri and A. lyrata showed the highest α values (0.25 and 0.27, respectively) (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37204299584&p=1pl&v=1&x=jPnch-e_YD0TBwdpam4EyA
10.1038/ncomms14514,Biology_easy_207,"The reason for the semiliquid, superionic property is the special structure of the nanoclusters, Jain said.","When all eight tetrahedral sites are filled, the {200} reflection is the strongest.","""We investigated further, and we realized that these small clusters are actually semiliquid at room temperature."" The reason for the semiliquid, superionic property is the special structure of the nanoclusters, Jain said. This crystal structure is a result of internal strain in the clusters.","When more of the tetrahedral sites are occupied by Cu þ , a {200} reflection originates from the Cu-Cu inter-planar arrangement with a spacing of a c /2 units. When all eight tetrahedral sites are filled, the {200} reflection is the strongest. The change in the experimental PXRD in going from 6 nm to the 4 nm NCs is exactly in line with such a change in the Cu þ sub-lattice.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/uNVFlIGRBVk/
10.1373/clinchem.2012.187617,Biology_easy_209,"Along with his gut bugs, the changes in how his genes expressed themselves were only temporary.",Such findings are intriguing and prompt questions regarding how microbial composition and corresponding metabolites may influence whole-body metabolism in humans and contribute to insulin resistance and diabetes.,"Within a few months of his return to Earth, this change actually reversed, returning his microbiome to its ""normal"" state. Along with his gut bugs, the changes in how his genes expressed themselves were only temporary. Ninety percent of his genetic levers -- including ones in charge of his immune system -- returned to normal six months after his return.","showed that in addition to the decreased abundance of Firmicutes, the Betaproteobacteria levels were significantly increased in diabetic patients compared to nondiabetic controls and their abundance significantly correlated with their plasma glucose concentrations (r ϭ 0.46, P Ͻ 0.05) . Such findings are intriguing and prompt questions regarding how microbial composition and corresponding metabolites may influence whole-body metabolism in humans and contribute to insulin resistance and diabetes. Mice lacking MyD88 were protected against insulitis , and this phenomenon depends on commensal microbes because germ-free MyD88 knockout mice develop robust diabetes.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1038/s41467-018-04151-6,Biology_easy_211,"""It is early days, but this opens the door to being able to modify cell networks with drugs and do it in a more robust and rigorous way.","This analysis provided a purely algebraic condition that must be satisfied by an RPA-capable system, which has been shown to be equivalent to the requirement for integral control 23 .","""Essentially we are now discovering the needles in the haystack in terms of the network constructions that can actually exist in nature. ""It is early days, but this opens the door to being able to modify cell networks with drugs and do it in a more robust and rigorous way. Dr Araujo said the published study was the result of more than ""five years of relentless effort to solve this incredibly deep mathematical problem"".","23 considered a special case of the IMP concerning RPA to constant exogenous inputs, in the context of providing a framework for understanding the extraordinary precision of adaptation in bacterial chemotaxis 5 . This analysis provided a purely algebraic condition that must be satisfied by an RPA-capable system, which has been shown to be equivalent to the requirement for integral control 23 . 23 , for the special case in which a particular input/output node pair is specified, thereby constructing a framework from which topological structures may be deduced relative to that input/output node pair.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BUs3tnStd9A/
10.1038/s41467-018-07557-4,Biology_easy_212,The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change.,Our results demonstrate that ca.,"""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change. ""The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved,"" the authors write.","Our study reveals the magnitude of the threat to engineering structures from climate change at the pan-Arctic scale, and shows where detailed infrastructure risk assessment should be conducted in the near future. Our results demonstrate that ca. The results show that most fundamental Arctic infrastructure will be at risk, even if the Paris Agreement target is achieved.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37952353365&p=1pl&v=1&x=z8k6aIsKNtvV0TWFOzO7Gg
10.1186/s13059-018-1434-0,Biology_easy_213,"""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities.""",We present evidence for extensive negative selection over somatic point mutations in cancer exomes.,"We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer. ""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities."" Interdisciplinarity and collaboration are the key success factors

This work, which has been published in Genome Biology, shows how interdisciplinary research pushes the boundaries of knowledge and contributes to finding new insights for improving health.",These studies help to shed light upon the mechanisms underlying immune evasion and provide insights for improving cancer immunotherapies in the future. We present evidence for extensive negative selection over somatic point mutations in cancer exomes. We exploited a large cancer exome dataset based on 26 tumor types and uncovered a set of 25 genes under negative selection (cancer-essential) and a set of 14 genes under positive selection (cancer drivers).,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.3945/jn.113.188441,Biology_easy_214,"Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies.","Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women.","In addition, men and women's varied eating habits and differences in the accuracy of food reporting may play a role in the gender gap. Regardless of the gender-related findings or their causes, Dr. Shin said, the study represents the importance of understanding the foods we feed our bodies. ""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said.","Consumption of instant noodles once per week was also associated with a higher prevalence of metabolic syndrome in women (OR: 1.26; 95% CI: 1.06, 1.50) but not in men. Further adjustment by sodium intake, estrogen use, menopause, or waist circumference also did not change the positive relation between instant noodle intake $2 times/wk and metabolic syndrome in women. Analysis adjusting for this pattern did not change associations between instant noodle intake and metabolic syndrome and abdominal obesity in women.",[1],Biology,train,1.0,news,http://www.newswise.com/articles/can-instant-noodles-lead-to-heart-disease-diabetes-and-stroke
10.1016/j.stemcr.2014.05.006,Biology_easy_215,"She added: ""We plan to further develop the methods from this study into an image processing and analysis software solution to be used for monitoring cell behaviour in applications such as screening culture conditions, drug discovery, monitoring and minimising the occurrence of genetic abnormalities directly through time-lapse.""","On the other hand, in subsequent cell divisions, the cell-cycle times for the normal and adapted cells, whether or not exposed to Y-27632, were similar, although there were small differences (Figures 2F and S2D) .","In the same culture condition, they found adapted cells performed better in all of these points leading to more colonies. Bottlenecks were also alleviated through cell to cell contact and pro-survival compounds. She added: ""We plan to further develop the methods from this study into an image processing and analysis software solution to be used for monitoring cell behaviour in applications such as screening culture conditions, drug discovery, monitoring and minimising the occurrence of genetic abnormalities directly through time-lapse.""","H14 normal and adapted cells displayed a similar pattern ( Figure S2C ). On the other hand, in subsequent cell divisions, the cell-cycle times for the normal and adapted cells, whether or not exposed to Y-27632, were similar, although there were small differences (Figures 2F and S2D) . Indeed, we conducted experiments with cells sorted based on SSEA3 expression and DNA content to show that the majority of dividing normal cells come from the G2 fraction ( Figure 3A ).",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/51952-time-lapse-study-reveals-bottlenecks-in-stem-cell-expansion.html
10.1073/pnas.1404354111,Biology_easy_216,"""Thrombopoietin signals actually acted on stem cells and progenitor cells, several generations back.""",This finding demonstrates a greater in vitro capacity for Mpl PF4cre/PF4cre preprogenitor cell self-renewal and secondary colony formation compared with Mpl fl/fl controls.,"""Thrombopoietin did not directly stimulate the platelet's 'parent' cells, the megakaryocytes, to make more platelets,"" Dr Ng said. ""Thrombopoietin signals actually acted on stem cells and progenitor cells, several generations back."" Dr Ng said the result was very surprising.","This effect was also evident for blast colonies derived from TPO Tg mice (SI Appendix, Fig. This finding demonstrates a greater in vitro capacity for Mpl PF4cre/PF4cre preprogenitor cell self-renewal and secondary colony formation compared with Mpl fl/fl controls. This data therefore provides evidence at the single-cell level that Mpl PF4cre/PF4cre multipotential preprogenitor cells, like those in TPO Tg mice, have characteristics of chronic excessive TPO exposure.",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/49516-solution-to-platelet-%E2%80%98puzzle%E2%80%99-uncovers-blood-disorder-link.html
10.1098/rsos.171474,Biology_easy_217,"In fact, the majority of people with mental health problems are not more likely to be violent.",We argue that this study speaks to the key question of whether adolescents' violent video game play has a measurable effect on real-world aggressive behaviour.,"There's also no evidence that either the El Paso or Dayton shooter was a fan of video games. In fact, the majority of people with mental health problems are not more likely to be violent. ""This difference is not explained by the rate of mental illness in the U.S,"" Evans said.","This pattern of findings further suggests that links reported in the literature might be influenced by publication bias, selective reporting, or an artefact of unobserved or hidden moderators, as has been previously suspected . We argue that this study speaks to the key question of whether adolescents' violent video game play has a measurable effect on real-world aggressive behaviour. On the basis of our evidence, the answer is no.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39881272230&p=1pl&v=1&x=agjUuQHKttCmyqc0lNUvPA
10.1016/j.cmet.2015.02.003,Biology_easy_218,"""I really think salt is an unappreciated factor of immunity,"" says Jantsch.",These findings suggest that immune cells entering wounded skin are exposed to a hypertonic interstitial microenvironment.,"A possible role of salt in the function of the immune system may be an evolutionary remnant from a time before antibiotics, when mammals, including humans, needed some methods of combating invading microbes, the researchers suggest. ""I really think salt is an unappreciated factor of immunity,"" says Jantsch. However, with the development of effective antibiotics and other infection treatments for infection, humans may no longer need huge amounts of salt in their system to protect them, the researchers note.","Infected mouse skin displayed $40 mmol/l increase in (Na + +K + )-to-water ratio, compared to plasma levels ( Figure 1D ). These findings suggest that immune cells entering wounded skin are exposed to a hypertonic interstitial microenvironment. A 40 mM increase in culture medium NaCl concentration (HS) boosted LPS-triggered induction of Nos2 on mRNA and protein level with enhanced NO release in RAW 264.7 MF and bone-marrow-derived MF (BMM) (Figure 2A ).",[1],Biology,train,1.0,news,http://www.techtimes.com/articles/37351/20150304/the-healthy-side-to-sodium.htm
10.1038/s41589-018-0155-8,Biology_easy_219,"advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says.","Among the more than 65 other serine hydrolases quantified by MS-based ABPP, only ABHD2 and PLA2G6 showed partial (~40-50%) reductions in activity in DO264treated mice ( Fig.","Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so. advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says. The findings suggest several possibilities to investigate with future research.","n = 4 and 3 independent experiments for c and d, respectively. Among the more than 65 other serine hydrolases quantified by MS-based ABPP, only ABHD2 and PLA2G6 showed partial (~40-50%) reductions in activity in DO264treated mice ( Fig. 4e and Supplementary Table 3 ); however, these changes may reflect an indirect outcome of ABHD12 inhibition, as DO264 did not inhibit mouse ABHD2 in vitro ( Supplementary  Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/s41467-018-04627-5,Biology_easy_220,"The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said.","These connections are known to mature relatively early; therefore, the subjects in our study may already be outside the sensitive period in which experience shapes these connections.","For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors. The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said. Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said.","Although we interpret this null result cautiously, one possibility is that differences in MD within posterior CC reflect relatively stable anatomical variation, which predicts reading skill, but does not change during short-term, intensive training. These connections are known to mature relatively early; therefore, the subjects in our study may already be outside the sensitive period in which experience shapes these connections. In that case, training at an earlier age might prompt changes in the CC alongside acquisition of reading skills.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34316135354&p=1pl&v=1&x=D1Z-S3HDnAF3EPGxC7uLSg
10.1126/sciadv.1601660,Biology_easy_221,"""We found, limited by the motor we used in the printing system, we could print at 200 millimeters per second, continuously, which is already competitive with the rates of industrial printing technologies.","These values represent approximately 30 and 60% of the conductivity of bulk Ag (6.3 × 10 7 S/m), respectively.","The key to printing tiny, precise, high-resolution patterns is in the amount of pressure applied to stamp the ink. ""We found, limited by the motor we used in the printing system, we could print at 200 millimeters per second, continuously, which is already competitive with the rates of industrial printing technologies. This, combined with a tenfold improvement in the printing resolution that we demonstrated, is encouraging.""","an array of lines (20 mm wide with pitch of 200 mm) reached 1.9 × 10 7 S/m, and after annealing for 120 min at 300°C, the conductivity increased to 4.0 × 10 7 S/m (Fig. These values represent approximately 30 and 60% of the conductivity of bulk Ag (6.3 × 10 7 S/m), respectively. 4C) shows how the nanoscale morphology of the printed features evolves during thermal annealing; at shorter times and lower temperatures, voids are present, whereas the highest conductivity is accompanied by a void-free nanocrystalline surface texture.",[1],Biology,train,1.0,news,http://news.mit.edu/2016/stamping-technique-printable-electronics-1207
10.1101/gad.263707.115,Biology_easy_222,"They showed that when fewer chemical groups of a certain type attach to yeast histones, the abnormal transcription greatly increases in old cells.","Among all of the 92 mutants tested, 33 showed life spans matching the screen predictions (35.9% replication rate).","This number - a mean of 25 divisions -- is under tight control and can be either reduced or increased by altering histone modifications, as the researchers found. They showed that when fewer chemical groups of a certain type attach to yeast histones, the abnormal transcription greatly increases in old cells. In contrast, the team found that in yeast strains with a certain enzyme deletion, this abnormal transcription is reduced and lifespan is extended by about 30 percent.","The results generally agreed, with a correlation coefficient of 0.78 between the two sets of experiments (Supplemental Fig. Among all of the 92 mutants tested, 33 showed life spans matching the screen predictions (35.9% replication rate). Although seemingly lower than expected, this is a success rate comparable with a previously published yeast chronological life span screen using the same histone mutant library ).",[1],Biology,train,1.0,news,http://www.newswise.com/articles/cell-aging-slowed-by-putting-brakes-on-noisy-transcription
10.1038/s41467-018-07557-4,Biology_easy_223,"""These observations have led me to believe that the global warming is not a 'fake' but the reality,"" Romanovsky said.","However, I s does not include information on permafrost thaw or other potential hazard-inducing factors and in our study, I s was based on relatively coarse-scaled GIC data.","""These observations have led me to believe that the global warming is not a 'fake' but the reality,"" Romanovsky said. ""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The research is the first to explicitly show the amount of fundamental infrastructure across the Northern Hemisphere that is at risk of structural failure from permafrost thaw caused by climate change.","The value of I a ranged from 1.0 (lowest hazard potential) to 3.0 (highest hazard potential). However, I s does not include information on permafrost thaw or other potential hazard-inducing factors and in our study, I s was based on relatively coarse-scaled GIC data. In contrast, I a considers different affecting factors and introduces case-specific expert knowledge into the process but represents a relatively complex and subjective approach in the development of an index for infrastructure hazard assessment.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37952353365&p=1pl&v=1&x=z8k6aIsKNtvV0TWFOzO7Gg
10.1038/s41467-019-09863-x,Biology_easy_224,"""True, we don't know exactly what society and the economy will look like 300 years in the future,"" he told E&E News.",The pursuit curve model ensures that there is an equilibrium level of cumulative carbon emissions from permafrost for any given level of warming globally (providing p > −1).,"It's a much longer-term vision than some other estimates present--many climate change projections tend to focus on 2100 as a benchmark. ""True, we don't know exactly what society and the economy will look like 300 years in the future,"" he told E&E News. ""But this is still a useful tool to get an idea of what that will look like in today's dollars.""","The latter allows us to use these sets of values to construct the corresponding probability distributions for ω,τ, p in PAGE-ICE, which are expected to work throughout the simulated range of temperatures. The pursuit curve model ensures that there is an equilibrium level of cumulative carbon emissions from permafrost for any given level of warming globally (providing p > −1). The dynamic model formulation employed here contains the following layers of nonlinearity: nonlinear response of the equilibrium cumulative carbon to GMST changes, represented by the ωφ ω (T)·T term; evolution of the characteristic time lag for cumulative permafrost emissions with the difference between the equilibrium and realised cumulative carbon, represented by p (in the corresponding linear model p = 0 and the lag is simply equal to τ); temperature-dependence in the lag and power parameters, represented by φ τ , φ p ; and, saturation of the cumulative carbon emissions due to the permafrost carbon stock exhaustion, represented by C max .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1126/science.1256773,Biology_easy_225,"What made this work possible was the realization that a controlled, flat membrane -- made from two layers of artificial lipid supported on glass -- could substitute for the curved, constantly moving and complex membrane of the cell.","At the cortical layer, F-actin organized into long, uniformly spaced cables that aligned radially with microtubules (Fig.","Quickly removing and returning proteins to see how changes in the molecular players affect cytokinesis is impossible when the cell is whole, but easy when the cellular innards are spread out on a microscope slide. What made this work possible was the realization that a controlled, flat membrane -- made from two layers of artificial lipid supported on glass -- could substitute for the curved, constantly moving and complex membrane of the cell. ""We believe our work is a step forward, not only for understanding the assembly of the cleavage furrow but also, more generally, for understanding the biophysics of cytokinesis signaling.""","Above the cortical layer, F-actin organized into branched networks that showed only partial alignment with the microtubules (Fig. At the cortical layer, F-actin organized into long, uniformly spaced cables that aligned radially with microtubules (Fig. The spacing between actin cables was 1.3 T 0.5 mm (SD; n = 140), comparable to the spacing of actincontaining contractile bands on the cortex of live frog eggs (19) .",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141031133545.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-019-09863-x,Biology_easy_226,"""The most important thing to remember about our study is the greater the warming, the stronger the feedbacks and the higher the costs to society.""",Robustness of the estimates for the PCF and SAF effects.,"But they are considerably lower for these scenarios compared to business as usual,"" said Yumashev. ""The most important thing to remember about our study is the greater the warming, the stronger the feedbacks and the higher the costs to society."" As National Geographic reported, the ""$25 to $70 trillion cost of Arctic warming adds four to six percent to the total cost of climate change--which is estimated to reach $1,390 trillion by the year 2300 if emissions cuts are not better than the Paris Agreement.","The economic losses due to climate warming also tend to be higher in warmer poorer regions such as India and Africa 20 , which are also less likely to benefit from the economic opportunities associated with a warmer Arctic 56 . Robustness of the estimates for the PCF and SAF effects. Other major feedbacks implemented in the fully-coupled GCMs such as clouds, water vapour and lapse rate contribute to overall uncertainty and state-dependency in the ECS parameter 35 .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39059198716&p=1pl&v=1&x=LFeOjGrAvD1wF12D7W6Wvg
10.1016/j.mito.2018.08.001,Biology_easy_227,"The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego.","Ultimately, it takes a season of about 3 months or more to fully commit to new foods, physical activities, and environmental exposures (sun, monsoons, droughts, hard freezes, etc) of the season.","The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego. A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first. When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors.","It takes more time to fully commit to the change. Ultimately, it takes a season of about 3 months or more to fully commit to new foods, physical activities, and environmental exposures (sun, monsoons, droughts, hard freezes, etc) of the season. Three months is also the average minimum time needed to demonstrate synaptic remodeling with exercise or meditation .",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ypj94azpXWE/
10.1038/s41467-018-04408-0,Biology_easy_228,"Ultimately, the researchers hope that their findings lead to more effective medications for lupus and other autoimmune diseases that impact so many women.","Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function.","Recognition of the link between testosterone and BAFF is completely new. Ultimately, the researchers hope that their findings lead to more effective medications for lupus and other autoimmune diseases that impact so many women. More: Fast Food Makes Your Immune System More Aggressive

""That's why this information about how the body regulates the levels of BAFF is extremely important, so that we can continue to put the pieces together and try to understand which patients should have BAFF inhibitors and which should not,"" Tivesten said in a statement.","Hence, estradiol elevates BAFF production and accelerates autoimmune disease , whereas testosterone has the opposite effects . Therefore, differences in the regulation of BAFF by estradiol and testosterone, potentially driven by nervous mechanisms, may contribute to the sex difference in autoimmune diseases in which BAFF has a pathogenic function. In conclusion, our study uncovers a previously unrecognized regulation of BAFF by testosterone.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34230456675&p=1pl&v=1&x=lt6z2jq1xfFKoXvXclXMKg
10.1016/j.cell.2015.07.058,Biology_easy_229,"Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea.","In contrast to DE1-virus-infected cells, WT, DE4-ORF3, DE1B-55K, and DE1B-55K/DE4-ORF3 virus infections all induce S phase entry to equivalent levels ( Figure 7A ).","This provides an elegant mechanism to neutralize viral replication without jeopardizing cellular viability. Image: Courtesy of the Salk Institute for Biological Studies

""What's interesting is that even a single break transmits a global signal through the cell, halting cell division and growth,"" says O'Shea. ""This response prevents replication so the cell doesn't pass on a break.""","The Localized MRN-ATM Anti-viral DDR Prevents Viral, but Not Cellular, Replication DDR foci play an important role in amplifying global DDR signaling, so that even a single DSB is sufficient to elicit cellcycle arrest . In contrast to DE1-virus-infected cells, WT, DE4-ORF3, DE1B-55K, and DE1B-55K/DE4-ORF3 virus infections all induce S phase entry to equivalent levels ( Figure 7A ). Consistent with this, CYCLIN A and CYCLIN B are also induced ( Figure 7B ).",[1],Biology,train,1.0,news,http://www.healthcanal.com/cancers/66433-the-dna-damage-response-goes-viral-a-way-in-for-new-cancer-treatments.html
10.1186/s13059-018-1434-0,Biology_easy_230,"""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes.","As such, the glucose metabolism-related genes discussed above are only found in this latter set, possibly reflecting the artificial nature of the in vitro environment used for essentiality experiments.","""We found that negative selection plays an important role in cancer evolution, which is quite controversial because it has been historically neglected in most studies and, ultimately, challenges the current paradigm of an exclusive role of positive selection in cancer,"" explains Dr. Schaefer. ""This is the first large scale study with a solid method to detect a substantial impact of negative selection in shaping cancer genomes. We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer.","In contrast, for the set of genes that are under negative selection but not cancer-essential, the strongest enrichment is for processes that depend on cell-environment interactions (e.g. As such, the glucose metabolism-related genes discussed above are only found in this latter set, possibly reflecting the artificial nature of the in vitro environment used for essentiality experiments. Indeed, a significantly lower d N /d S value is associated with the epitope regions across 26 tumor types irrespective of the HLA type of the patient (P < 0.0001; permutation test; see ""Methods"" section; Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1016/j.cmet.2015.02.003,Biology_easy_231,"""We are interested in how this works, because it can have broad applications,"" says Jantsch.",Large amounts of Na + are stored in the skin.,"And for those with hyperactive immune responses, dialing down the concentration of sodium at specific areas might also be helpful. ""We are interested in how this works, because it can have broad applications,"" says Jantsch. ""We can possibly target and boost sodium in situations where we need more salt if it's deficient, and lower it in situations where there is salt overload and hypertension.""",Na + metabolism may represent an unappreciated functional component of skin barrier formation. Large amounts of Na + are stored in the skin. This age-dependent Na + accumulation is associated with primary (essential) and secondary hypertension .,[1],Biology,train,1.0,news,http://time.com/3730061/the-weird-benefit-of-eating-salty-food/
10.1038/s41598-017-05868-y,Biology_easy_232,"Importantly, the team found that pericytes produced 40-times more leptin when exposed to low levels of oxygen and that this continued until oxygen levels returned to normal.","In four biological replicates, here we demonstrate APCs have similar morphology when cultured under normoxia or hypoxia, as assessed by contrast phase microscopy (Supplementary Figure Ia) .","In the longer term, these findings may help in the development of an alternative treatment to major surgery for heart attack patients. Importantly, the team found that pericytes produced 40-times more leptin when exposed to low levels of oxygen and that this continued until oxygen levels returned to normal. This may help tissues to build more blood vessels to increase blood flow and oxygen supply.","We succeeded in isolating and expanding 21 APC lines (88% of processed veins), using a standard protocol described in the methods section and previous publications . In four biological replicates, here we demonstrate APCs have similar morphology when cultured under normoxia or hypoxia, as assessed by contrast phase microscopy (Supplementary Figure Ia) . Likewise, hypoxia does not alter the expression of surface markers, as identified by flow cytometry and immunocytochemistry (Supplementary Figure Ib-e and Supplementary Table II) .",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/new-discovery-could-reverse-tissue-damage-caused-by-heart-attacks/
10.1186/s40168-015-0071-z,Biology_easy_233,"That kind of sounds bad, but there is an upside, and it appears to depend partially on the mother's DNA.","A principle coordinate analysis of the marker gene sequencing results revealed three main clusters of samples, (Additional file 6: Figure S3 , middle plot) with one outlier.","That kind of sounds bad, but there is an upside, and it appears to depend partially on the mother's DNA. ""Bifidobacteria sort of push other bacteria out. So those women make much less of the special sugar.","Results indicated that genera Bifidobacterium and Bacteroides were the top two contributors to differences among the given inputs (rho statistic = 0.586 when only those two factors are considered, see Additional file 5: Table S3) . A principle coordinate analysis of the marker gene sequencing results revealed three main clusters of samples, (Additional file 6: Figure S3 , middle plot) with one outlier. The three clusters were respectively distinguished by high bifidobacterial content (BI), high Bacteroides (BA), and high levels of a number of other taxa including streptococci, enterobacteria, and clostridial species (OT) (see Additional file 6: Figures S3, Additional file 7: Figure S4 , Additional file 8: Figure S5 , Additional file 9: Figure S6 ).",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1038/nature24621,Biology_easy_234,"""These global ecological patterns offer just a glimpse of what is possible with coordinated and cumulative sampling,"" Jansson says.",The failure of many sequences to be mapped in referencebased alignments to Greengenes and SILVA 97% identity OTUs (Extended Data Fig.,"Overall, the microbiomes of a host, such as a human or animal, were quite distinct from free-living microbiomes, such as those found in water and soil. ""These global ecological patterns offer just a glimpse of what is possible with coordinated and cumulative sampling,"" Jansson says. ""More sampling is needed to account for factors such as latitude and elevation, and to track environmental changes over time.","These matches accounted for 10% and 13%, respectively, of the tag sequences in our dataset, indicating that large swathes of microbial community diversity are not yet captured in full length sequence databases. The failure of many sequences to be mapped in referencebased alignments to Greengenes and SILVA 97% identity OTUs (Extended Data Fig. 2b ) supports this observation.",[1],Biology,train,1.0,news,http://www.futurity.org/earth-microbiome-project-1595972/
10.1073/pnas.1318978111,Biology_easy_235,Hammes says the study calls for further clinical trials to determine whether androgens can have a positive effect on fertility when given at the right doses.,This demonstration of a conserved function of paxillin in vastly different cell types validates the importance of paxillin as a general liaison between extranuclear and nuclear AR signaling.,"""If these data are confirmed in clinical trials, we could propose that raising low levels of androgens in a woman with diminished ovarian reserve might increase her ability to produce more and better eggs for fertilization."" Hammes says the study calls for further clinical trials to determine whether androgens can have a positive effect on fertility when given at the right doses. And, by better understanding the biological pathways that are important for follicle development, scientists may be able to target these pathways with drugs or other interventions to improve IVF success rates.","Once in the nucleus, PS-paxillin then regulates AR nuclear localization and AR-mediated transcription . This demonstration of a conserved function of paxillin in vastly different cell types validates the importance of paxillin as a general liaison between extranuclear and nuclear AR signaling. By increasing FSHR expression, we show that androgens then enhance sensitivity to FSH-induced follicle growth and progression to the antral stage.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/03/140304141948.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rsos.171474,Biology_easy_236,She said the burden will fall to elected officials at the state level.,These results did not support our prediction that there are statistically significant links relating violent gaming to adolescents' aggressive behaviour using the current operationalization of violent gaming.,"Percio also suggested that Trump will not do anything about white supremacy. She said the burden will fall to elected officials at the state level. Many point to the research, which suggests there is no connection between video games and real-world violence.","Results from this model, presented in table 3, indicated both the linear ( p ¼ 0.899) and parabolic ( p ¼ 0.851) predictors were not statistically significant. These results did not support our prediction that there are statistically significant links relating violent gaming to adolescents' aggressive behaviour using the current operationalization of violent gaming. Two novel research questions which were not included in our Stage 1 submission came to mind after the manuscript was accepted, in principle, and data collection was completed.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39882679749&p=1pl&v=1&x=6vdDlJz_W42omdcCubQOqg
10.1126/science.1256773,Biology_easy_237,"The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract.","Depletion of Kif4A did not block CPC accumulation or the assembly of antiparallel bundles, but increased the width of the CPC-positive zone; adding back recombinant Kif4A rescued this phenotype ( Fig.","""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane. The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract. ""It's not only microtubules signaling to the plasma membrane, but also microtubules signaling to the actin cortex that forms on top of the plasma membrane,"" Nguyen said.","Small-molecule inhibition of Kif10 and Kif11, and depletion of somatic Kif20A and Kif23, had no effect on antiparallel microtubule bundling in the AAIZ or on CPC localization (Fig. Depletion of Kif4A did not block CPC accumulation or the assembly of antiparallel bundles, but increased the width of the CPC-positive zone; adding back recombinant Kif4A rescued this phenotype ( Fig. Depletion of Kif20AE completely blocked CPC accumulation and disorganized the AAIZ (Fig.",[1],Biology,train,1.0,news,http://www.science20.com/news_articles/cytokinesis_lite_cellular_division_now_with_no_cells-148202
10.1038/s41589-018-0155-8,Biology_easy_238,"Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so.","DO264-treated mice, however, show minimal impairment in auditory function following four weeks of drug exposure.","Ordinary mice infected with LCMV clone 13 typically have minor symptoms but take a long time to clear the infection. Teijaro and colleagues found that the ABHD12-knockout mice, as well as the mice treated with the ABHD12 inhibitor, had immune responses that were much more vigorous and effective in clearing the virus, often excessively so. advertisement

""The enhanced mortality and lung pathology were striking in clone-13 infected mice following ABHD12 inhibition or deletion,"" Teijaro says.","Mice treated with DO264 display dosedependent increases in brain lyso-PS and 20:4 PS content that are qualitatively similar to the changes observed in ABHD12 -/mice. DO264-treated mice, however, show minimal impairment in auditory function following four weeks of drug exposure. We also found that DO264 elevated the lyso-PS and 20:4 PS content of primary human macrophages.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1038/s41598-019-40955-2,Biology_easy_239,"The unit plans to put this theory to the test in future studies, as they continue to collect genomic data from brown seaweeds across Okinawa and greater Japan.","We isolated mRNA indicating that in C. okamuranus, these two genes have fused, which may be advantageous for producing fucoidan.","The researchers uncovered an additional pair of fused genes in ito-mozuku that they didn't find in Okinawa mozuku. They predict that, when expressed, these genes may boost the number of sulfate groups transferred to fucoidan, a chemical reaction that may be key to the substance's health benefits. The unit plans to put this theory to the test in future studies, as they continue to collect genomic data from brown seaweeds across Okinawa and greater Japan.","It is reported that approximately 800 tons of N. decipiens were produced in fiscal year 2017, versus ~17,000 tons of C. okamuranus. We isolated mRNA indicating that in C. okamuranus, these two genes have fused, which may be advantageous for producing fucoidan. The Illumina MiSeq platform (average library size, 700 base-pair (bp)) generated a total of 47.1 giga-base-pair (Gbp) of paired-end sequence data (average read length = 309 bp).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38763824360&p=1pl&v=1&x=EwLVh9xrW10mzhFmqvXNkA
10.1016/j.compag.2016.07.028,Biology_easy_240,"""How to capture all of these dynamic traits is really a challenging task without these high-throughput systems,"" Ge said.","Total NIR reflectance appears to be influenced by leaf thickness in addition to water content, introducing confound- ing variation ( .","Hyperspectral and RGB imaging not only address this issue, Ge said, but should also further speed the process of simultaneously comparing multiple traits among plant varieties. ""How to capture all of these dynamic traits is really a challenging task without these high-throughput systems,"" Ge said. We can analyze the growth rate and look at the changes over time at different developmental stages.","Compared to leaves, these organs have subtle differences in spectral signatures, which would lower the prediction accuracy. Total NIR reflectance appears to be influenced by leaf thickness in addition to water content, introducing confound- ing variation ( . Here we show that hyperspectral imaging can predict LWC accurately (in case of B73, a prediction accuracy of ±2.3% is achieved as indicated by RMSE CV ).",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/JM-jhIn6rZA/
10.1093/jee/tou026,Biology_easy_241,"""It may have a wider host range than we ever thought in the first place, or it is adapting to utilize new hosts.",Infestation of ash trees by emerald ash borer became visibly apparent for the first time in the village and nearby areas in 2012 (personal observation).,"Additional white fringetrees exhibiting evidence of emerald ash borer attack were also found in Springfield and Dayton, Ohio. ""It appears that emerald ash borer is eating more than ash trees,"" Cipollini said. ""It may have a wider host range than we ever thought in the first place, or it is adapting to utilize new hosts.","White fringetree is in the same family as ash trees, and planted individuals and wild populations will come increasingly in contact with emerald ash borer as it spreads to the southeastern United States. Infestation of ash trees by emerald ash borer became visibly apparent for the first time in the village and nearby areas in 2012 (personal observation). On 17 August 2014, I found that one of the white fringetrees along the trail ( Fig.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/01/150115102827.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1373/clinchem.2012.187617,Biology_easy_242,These little guys play a huge role in regulating our health and make it possible for us to live in the way we're used to.,"After 2 weeks, mice that received microbiota from the ob/ob mice were able to extract more calories from food and also showed a significantly greater fat gain than mice that received the microbiota from lean mice.",These little guys play a huge role in regulating our health and make it possible for us to live in the way we're used to. This is actually through our microbiome's connection to the immune system. They aren't hurting us as long as they stay under control.,"The composition of the gut microbiome seems to be important in regulating body weight . After 2 weeks, mice that received microbiota from the ob/ob mice were able to extract more calories from food and also showed a significantly greater fat gain than mice that received the microbiota from lean mice. Thus, differences in caloric extraction of ingested food substances may be largely a result of the composition of the gut microbiota.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=40253496747&p=1pl&v=1&x=Ul5zHhtDyat4L2c3FwEaew
10.1038/s41467-017-01957-8,Biology_easy_243,"As our experiments demonstrate, they can shift depending on whether or not the predator had time to adapt.""","When m < 1, it is convex and defense is costly.","""This is, of course, beneficial to the prey and could reduce the pressure on the bacteria"", says Becks. The study shows that, surprisingly, more prey diversity does not always mean more predator diversity. As our experiments demonstrate, they can shift depending on whether or not the predator had time to adapt.""","When m > 1, the trade-off function is concave and defense is cheap. When m < 1, it is convex and defense is costly. If the predator coevolves with the prey, the trade-off curves change, e.g., b, c show the trade-off curves under evolved predators with higher predation abilities, i.e., k l /k max equals to 1/3 or 1/30, respectively.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/5JFO6NDeMfE/
10.1186/s40168-015-0071-z,Biology_easy_245,"""It shows that establishing the microbiome is an intricate process, orchestrated by the breast milk.""",Of the oligosaccharides not ostensibly consumed by B. longum subsp.,"""I think it's exciting how just a single gene is enough to change the baby's microbiome,"" Lewis said. ""It shows that establishing the microbiome is an intricate process, orchestrated by the breast milk."" The research doesn't imply that there is any specific health repercussions with babies getting the gene, but it's something that is worth noting.","infantis were shown to have a higher percentage of nonfucosylated neutral oligosaccharides left behind in the feces. Of the oligosaccharides not ostensibly consumed by B. longum subsp. infantis, 52.3% ± 5.8% were nonfucosylated neutral species on average.",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1038/s41467-019-09863-x,Biology_easy_247,"Eno e omada tou Yumashev kataskeuase tis mellontikes sunthekes tes klimatikes allages, mia melete pou demosieuteke prosphata sto Proceedings of the National Academy of Sciences ektima ten pagkosmia oikonomike zemia pou ekhei ede proklethei.",These increases are statistically significant (5% level).,"Tetoia metra perilambanoun ten ektetamene epharmoge ananeosimon energeion opos e eliake energeia. Eno e omada tou Yumashev kataskeuase tis mellontikes sunthekes tes klimatikes allages, mia melete pou demosieuteke prosphata sto Proceedings of the National Academy of Sciences ektima ten pagkosmia oikonomike zemia pou ekhei ede proklethei. Sto metaxu, khores opos e Norbegia, o Kanadas kai e Souedia einai 25-34% pio plousies ap' o,ti tha etan khoris tis pio megales pagkosmies thermokrasies.","When the nonlinear PCF and SAF representations are combined, the statistical mean of the economic effect of climate change increases relative to the base estimate with the legacy PCF and SAF by $16.1 trillion (1 trillion = 10 12 ) for the counterfactual Zero Emissions scenario ($1288 trillion base estimate), $24.8 trillion for 1.5°C target ($613 trillion base estimate), $33.8 trillion for 2.0°C target ($613 trillion base estimate), $50.3 trillion for 2.5°C target ($815 trillion base estimate), $66.9 trillion for NDCs ($1390 trillion base estimate), and by $59.8 trillion for NDCs Partial ($1702 trillion base estimate). These increases are statistically significant (5% level). We also found marginal but statistically insignificant increases for BaU ($2197 trillion base estimate), which remains the most expensive and least desirable scenario.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39093010673&p=1pl&v=1&x=sZM4NVw7ruP2hKMrRk-2DA
10.1038/s41568-018-0020-9,Biology_easy_248,"I look forward to seeing how the combination of these therapies can affect outcomes in patients for whom this resistance is associated with poor prognoses.""","In some cases, these context-dependent functions include the activation of signalling pathways in certain leukaemias 73 , the processing of key mRNAs of lymphoma subtypes 78 and the maintenance of the viral oncoproteome in gammaherpesvirusassociated malignancies 74 .","By inhibiting epichaperome function and breaking this mechanism, we believe PU-H71 can increase anti-cancer activity of JAK2 inhibitors. I look forward to seeing how the combination of these therapies can affect outcomes in patients for whom this resistance is associated with poor prognoses."" The multicenter Phase 1b study is designed to assess the safety, tolerability, PK and preliminary efficacy of PU-H71 in subjects taking concomitant ruxolitinib.","These high-affinity chaperome complexes may help organize and maintain the function of the oncoprotein complement of a cancer cell in a tumour-specific and transformation-specific manner. In some cases, these context-dependent functions include the activation of signalling pathways in certain leukaemias 73 , the processing of key mRNAs of lymphoma subtypes 78 and the maintenance of the viral oncoproteome in gammaherpesvirusassociated malignancies 74 . b | Formation of the chaperome platforms enables a dynamic adaptation to acute insults, providing a protective mechanism for cells under transient stress.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34294149057&p=1pl&v=1&x=pzihluZRVcZJ0XNPGmH0Mw
10.1186/s40168-015-0071-z,Biology_easy_249,"The research doesn't imply that there is any specific health repercussions with babies getting the gene, but it's something that is worth noting.","Pairwise comparison of the lactate results found no significant differences between BI PCoA and BA PCoA groups, but found that the OT PCoA group was lower than both the BI PCoA group and the BA PCoA group with p < 0.0001 in each case.","""It shows that establishing the microbiome is an intricate process, orchestrated by the breast milk."" The research doesn't imply that there is any specific health repercussions with babies getting the gene, but it's something that is worth noting. ""If you're living in an unhygienic home, the baby will have a completely different microbiome than one in a home that gets Cloroxed every day,"" Lewis says.","In the groups based off of PCoA clustering (BA PCoA , BI PCoA , OT PCoA ), lactate was found to have significant differences by ANOVA. Pairwise comparison of the lactate results found no significant differences between BI PCoA and BA PCoA groups, but found that the OT PCoA group was lower than both the BI PCoA group and the BA PCoA group with p < 0.0001 in each case. Conversely, term milk glycan compositions appear relatively stable throughout lactation, perhaps highlighting their importance to the developing infant .",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1016/j.cell.2013.08.004,Biology_easy_252,The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders.,Our data show both in vitro and in vivo that CRTC1 translocates to the nucleus after phase-shifting stimuli and acts as a coactivator of CREB-driven transcription of Sik1 and Per1.,"""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and working as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules,"" said Duffield. The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders. This drug could potentially protect against diseases and mental disorders that are brought on by disturbances of the circadian rhythms.","From these, we defined a key role for the CRTC-SIK1 pathway in regulating CREB-mediated clock gene expression. Our data show both in vitro and in vivo that CRTC1 translocates to the nucleus after phase-shifting stimuli and acts as a coactivator of CREB-driven transcription of Sik1 and Per1. Following in vitro Crtc silencing, induction of Per1 and other CREB-mediated genes is greatly attenuated.",[1],Biology,train,1.0,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1016/j.immuni.2019.05.007,Biology_easy_254,Note: material may have been edited for length and content.,"Overlay of Fab A1227 onto the GI.1 capsid structure (Figures 4E and 4F) indicated that other P domains on the assembled norovirus capsid would clash with both heavy and light chains of the Fab, with only minor clashes with the shell domains ( Figure 4G ), suggesting that structural rearrangements of the P domain could either expose the A1227 binding site or allow binding at a neighboring P domain.","Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Note: material may have been edited for length and content. For further information, please contact the cited source.","Modeling revealed that the conserved region recognized by A1227 was located at an occluded site on the norovirus capsid, at the interface between the P domain and shell domain. Overlay of Fab A1227 onto the GI.1 capsid structure (Figures 4E and 4F) indicated that other P domains on the assembled norovirus capsid would clash with both heavy and light chains of the Fab, with only minor clashes with the shell domains ( Figure 4G ), suggesting that structural rearrangements of the P domain could either expose the A1227 binding site or allow binding at a neighboring P domain. Its lack of blockade or neutralizing activity likely results from antibody A1227 only recognizing defects or maturation intermediates (Pogan et al., 2018).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39496179252&p=1pl&v=1&x=1Ybn3Q7h2gozRyncgH43aA
10.1016/j.cell.2018.04.038,Biology_easy_255,"""At each step, we zoom in closer and see more and more details, and can now begin to deduce not just what the enzyme looks like, but also how it functions.",tions ( Figure 5C ).,"""At each step, we zoom in closer and see more and more details, and can now begin to deduce not just what the enzyme looks like, but also how it functions. Knowing that may lead to the development of new drugs that target specific parts of the enzyme."" In addition to reporting the highest level of detail ever seen of the structure of telomerase's catalytic core, shown in the animation below, the researchers report for the first time they have captured telomerase in the process of making DNA.","The DNA-template duplex exits the TERT ring toward the TRAP, where the sstDNA and TRE L continue in opposite direc- Figure S3 . tions ( Figure 5C ). After the last base pair, the sstDNA turns back toward the 5 0 end of the template, while the TRE L turns away from the duplex through the CTE-TRAP channel ( Figures 4D and 5C ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1038/s41467-019-09863-x,Biology_easy_256,"Thus, the nonlinear Arctic feedbacks make the more ambitious 1.5C target marginally more economically attractive.",The differences are the highest for BaU with nearly ice-free oceans and snow-free land even in winter after 2200.,"Nonlinear PCF and SAF add further $25 trillion to the $600 trillion figure for the 1.5C scenario and $34 trillion for the 2C scenario. Thus, the nonlinear Arctic feedbacks make the more ambitious 1.5C target marginally more economically attractive. Dr Yumashev added: ""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2C.","The NDCs, NDCs Partial and BaU scenarios have the largest temperature increases and greatest decreases in land snow and sea ice SAF components, and thus show the greatest negative differences in GMST. The differences are the highest for BaU with nearly ice-free oceans and snow-free land even in winter after 2200. For the Zero Emissions, 1.5°C, 2.0°C and 2.5°C scenarios, there are small increases in GMST for the entire time period due to the small peaks in the sea ice and land snow SAF components within this temperature range (Fig.",[1],Biology,train,1.0,news,https://www.sciencedaily.com/releases/2019/04/190423114027.htm
10.1016/j.immuni.2019.05.007,Biology_easy_257,"The authors noted that ""each of these antibody classes may contribute to vaccine-induced protection, and further studies and in vivo models are required to fully understand the interplay between the antibody targets and the physiological response.""",The CDR-H3 loop of A1431 was (G) Quantification of volume overlap between A1227 Fab (or VH/VL) and GI.1 capsid proteins.,"The authors write that ""structural mapping revealed conserved epitopes, which were occluded on the virion or partially exposed, allowing for broad blockade with neutralizing activity."" These results demonstrate that infection-derived and vaccine-elicited antibodies can exhibit broad blockade and neutralization against this prevalent human pathogen. The authors noted that ""each of these antibody classes may contribute to vaccine-induced protection, and further studies and in vivo models are required to fully understand the interplay between the antibody targets and the physiological response.""",Both A1431 heavy and light chains contributed to the binding interface with a total buried surface area of $985 Å 2 on the P domain. The CDR-H3 loop of A1431 was (G) Quantification of volume overlap between A1227 Fab (or VH/VL) and GI.1 capsid proteins. Over 60% of the volume of A1227 Fab overlaps with neighboring P domains when modelled onto either A/B or C/C dimers.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39497202582&p=1pl&v=1&x=Ax4CZfiIW69ZKRWE5VBL1A
10.1016/j.cell.2018.04.038,Biology_easy_258,"""I remember looking at this structure when we got it and thinking we had solved a significant piece of the puzzle and were the only people who had seen this.",The IFD helices are positioned similarly to those in group II intron and PLE reverse transcriptases on the periphery of the protein ( Figure 3B ).,"The researchers report for the first time the structure, shape and significance of TRAP, and the region with which it interacts. ""I remember looking at this structure when we got it and thinking we had solved a significant piece of the puzzle and were the only people who had seen this. Many mutations that scientists attributed to the TEN region in fact disrupt TEN's interaction with TRAP, the researchers report in Cell.","In Tetrahymena, the linker (IFDb) between the two IFD helices (IFDa and IFDc) is 104 aa, 30% of the RT sequence ( Figure 2A ). The IFD helices are positioned similarly to those in group II intron and PLE reverse transcriptases on the periphery of the protein ( Figure 3B ). The structure of TRAP is comprised primarily of b strands and loops, and the backbone could be traced and tentative residue assignments made for all but a 23-residue highly acidic and apparently unstructured loop at the end of the L ( Figures  3C and 3D ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34239565585&p=1pl&v=1&x=dKdwlCB2iE4axi2krXvE_w
10.1186/s40168-015-0071-z,Biology_easy_259,The former also tended to pick up the bacteria later.,"In all other cases, the homozygotic and heterozygotic secretors were determined to have a secretor phenotype.","Babies whose moms carry the mutation had about 10 times fewer Bifidobacteria in their guts, on average, than the babies whose moms had a working version of the gene. The former also tended to pick up the bacteria later. ""I think it's exciting how just a single gene is enough to change the baby's microbiome,"" Lewis said.","In two cases (mothers 1036 and 1041), the genotypic data showed either homozygote secretor or heterozygote (respectively), but the phenotype indicated non-secretor. In all other cases, the homozygotic and heterozygotic secretors were determined to have a secretor phenotype. In the two aberrant cases, later time points revealed secretor levels of 2′-fucosylation in these two mothers, suggesting that secretor phenotype might change over the course of lactation in some mothers.",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1038/onc.2016.381,Biology_easy_260,"So not only did Kleer gain a better understanding of CCN6, but her lab's findings open the door to a better understanding of this very challenging subtype of breast cancer.","We observed no difference among any of the control mice genotypes when considering histological and morphological phenotype, immunoblots or qPCR data; therefore, the wild-type control groups presented here consist of a mixture of all of the genotypes.","Only 1 percent are metaplastic. So not only did Kleer gain a better understanding of CCN6, but her lab's findings open the door to a better understanding of this very challenging subtype of breast cancer. The study is published in Oncogene.","Based on this analysis, two out of the five expanded clones (B7 and B8) were confirmed for homologous recombination with single neo integration. Amplification with these primers results in a 196-bp fragment from the CCN6 WT allele and a 344-bp fragment from the CCN6 fl allele after neo deletion. We observed no difference among any of the control mice genotypes when considering histological and morphological phenotype, immunoblots or qPCR data; therefore, the wild-type control groups presented here consist of a mixture of all of the genotypes.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/researchers-find-key-genetic-driver-for-rare-type-of-triple-negative-breast-cancer/
10.1016/j.neuron.2018.12.026,Biology_easy_262,Note: material may have been edited for length and content.,RS and FS spikes were wellseparated by a spike width criterion of 0.45 ms.,"He is continuing his studies to determine what other effects lowered inhibition have that could explain autism symptoms. Note: material may have been edited for length and content. For further information, please contact the cited source.","This view predicts that enhancing inhibition may be insufficient to normalize ASD symptoms in cases or brain areas where effective E-I homeostasis (i.e., that normalizes cortical spike rate) has taken place. RS and FS spikes were wellseparated by a spike width criterion of 0.45 ms. Relatively high FS firing rates in awake mice prevented effective sorting and analysis of most FS single units, so only L2/3 RS units were analyzed.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1098/rsos.171474,Biology_easy_263,"We must stop or substantially reduce this, and it has to begin immediately.""",These results did not support our prediction that there are statistically significant links relating violent gaming to adolescents' aggressive behaviour using the current operationalization of violent gaming.,"He also brought up the video game industry, believing the multi-billion dollar industry played a role in the weekend's tragedies. We must stop or substantially reduce this, and it has to begin immediately."" When you look at these photos of how it took place, you can see the actions within videogames.""","Results from this model, presented in table 3, indicated both the linear ( p ¼ 0.899) and parabolic ( p ¼ 0.851) predictors were not statistically significant. These results did not support our prediction that there are statistically significant links relating violent gaming to adolescents' aggressive behaviour using the current operationalization of violent gaming. Two novel research questions which were not included in our Stage 1 submission came to mind after the manuscript was accepted, in principle, and data collection was completed.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39874484563&p=1pl&v=1&x=Bj3Jg8jT1PnJ7P0ExZGe-A
10.1016/j.cell.2013.08.004,Biology_easy_264,The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders.,"We found that of the genes upregulated more than 1.5-fold, there was significant enrichment of those containing CRE sites near the TATA box ( Figure 1C ).","""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and working as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules,"" said Duffield. The discovery of the role that SIK1 plays in the body clock welcomes the possible innovation of a new drug that can treat jet lag and shift work disorders. This drug could potentially protect against diseases and mental disorders that are brought on by disturbances of the circadian rhythms.","One category of interest that is significantly responsive to light includes a number of transcripts relating to synaptic remodeling and plasticity, which were upregulated at a late stage, and included Raspgrp1, Grit, and Ntng1. We found that of the genes upregulated more than 1.5-fold, there was significant enrichment of those containing CRE sites near the TATA box ( Figure 1C ). This correlation implies that CREB drives the high-magnitude gene induction that underlies phase-shifting responses in the SCN.",[1],Biology,train,1.0,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1038/nrg2703,Biology_easy_265,"MacGregor Campbell/OPB

It helps to know a little bit about why pollen exists in the first place.","The sequence of individual LRR modules assembled into the VLR gene is highly diverse, and the number of LRR modules present in a rearranged gene varies from one to nine.","You'd think we'd have had plenty of time to evolve a way to deal with it. MacGregor Campbell/OPB

It helps to know a little bit about why pollen exists in the first place. It just takes one grain to fertilize the female part of a plant, so casting fate to the wind isn't a bad strategy.","Incorporation is presumably mediated by cytidine deaminases of the AID-APOBeC family . The sequence of individual LRR modules assembled into the VLR gene is highly diverse, and the number of LRR modules present in a rearranged gene varies from one to nine. Therefore a single VLR gene can have combinatorial diversity comparable to that of Igs (~10 14 combinations) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34307692391&p=1pl&v=1&x=mm-osFSBw9YRNm7JQuxdew
10.1038/s41467-019-09863-x,Biology_easy_266,Nonlinear PCF and SAF add further $25 trillion to the $600 trillion figure for the 1.5C scenario and $34 trillion for the 2C scenario.,"Considering the nonlinear Arctic feedbacks makes the 1.5°C target marginally more economically attractive than the 2°C target, although both are statistically equivalent.","With previous estimates for Arctic feedbacks, the total cost of climate change associated with the 1.5C and 2C scenarios is virtually the same and is around $600 trillion -- in comparison, the estimated cost of business as usual is around $2000 trillion. Nonlinear PCF and SAF add further $25 trillion to the $600 trillion figure for the 1.5C scenario and $34 trillion for the 2C scenario. Thus, the nonlinear Arctic feedbacks make the more ambitious 1.5C target marginally more economically attractive.","Combined, these two factors lead to significant increases in the mean discounted economic effect of climate change: +4.0% ($24.8 trillion) under the 1.5°C scenario, +5.5% ($33.8 trillion) under the 2°C scenario, and +4.8% ($66.9 trillion) under mitigation levels consistent with the current national pledges. Considering the nonlinear Arctic feedbacks makes the 1.5°C target marginally more economically attractive than the 2°C target, although both are statistically equivalent. T he Arctic region is warming twice as fast as the global average 1 , manifested by a decrease in sea ice, snow and glaciers and permafrost degradation relative to their benchmark average states for the period between 1979 and 2005 .",[1],Biology,train,1.0,news,https://www.sciencedaily.com/releases/2019/04/190423114027.htm
10.1016/j.cell.2013.08.004,Biology_easy_267,"The clock needs to be sure that it is getting a reliable signal, and if the signal occurs at the same time over several days it probably has biological relevance.",Faster re-entrainment was observed with the Sik1 knockdown (siSik1) mice.,"If you think about, it makes sense to have a buffering mechanism in place to provide some stability to the clock. The clock needs to be sure that it is getting a reliable signal, and if the signal occurs at the same time over several days it probably has biological relevance. But it is this same buffering mechanism that slows down our ability to adjust to a new time zone and causes jet lag.""","(B) Phase-shifting responses to light are significantly larger following knockdown of Sik1 in the SCN (siSik1) when compared to nontargeting siRNA (siNT) controls (98 min versus 59 min, p = 0.036, Student's t test, n = 5). Faster re-entrainment was observed with the Sik1 knockdown (siSik1) mice. ** = p < 0.01, * = p < 0.05 Student's t test, phase of siSik1 versus siNT-treated animals on each day, n = 6 for siNT, n = 11 for siSik1.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/08/130829124013.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rsos.171474,Biology_easy_268,"But once you get the hands-on experience, you see that this is a pretty silly idea.""","For both self-reported and behavioural aggression measures, this flexibility affords otherwise well-meaning researchers the ability to select between different operationalizations of predictors and outcomes until they find a combination in line with their pre-existing biases or theories.","He found that people who have never played video games before are more likely to have biases about them and unrealistic expectations about them. ""They might think Fortnite is violent or that people who play Mario are more likely to be aggressive towards turtles. But once you get the hands-on experience, you see that this is a pretty silly idea.""","A similar tractability is present in behavioural measurements of aggression. For both self-reported and behavioural aggression measures, this flexibility affords otherwise well-meaning researchers the ability to select between different operationalizations of predictors and outcomes until they find a combination in line with their pre-existing biases or theories. Given these findings and the wider importance of conclusions drawn from this work, it is important to use preregistered study methodology to evaluate whether the existing literature may be under-or over-estimating the extent to which violent video game play relates to aggression.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39882021759&p=1pl&v=1&x=WDSVA9_GGY2tcF2kX9kO8w
10.1038/s41467-018-04355-w,Biology_easy_269,They also demonstrated that the presence of a clot made it easier for cancer cells to move and migrate.,These results were confirmed also using the Spearman's rank correlation coefficient.,"By genetically modifying the expression of CCL2 in a metastasis model developed in their laboratory, they found low expression was linked to reduced metastases, while high expression was linked to enhanced metastatic features. They also demonstrated that the presence of a clot made it easier for cancer cells to move and migrate. Also, when looking at tumor samples from patients, they found that tumors with high amounts of the fibrin cross-linking was associated with an increased risk of the tumor spreading.","Notably, the precise gene where the HM is split turned out to be not critical, since the last gene having statistical relevance for survival in the upper HM portion is gene #2261 (TKTL1). These results were confirmed also using the Spearman's rank correlation coefficient. Notably, this simple mathematical rule splits the HM into two identical parts either using the Secretory subtype or the PS aggregate as a reference (i.e., the ""splitting point"" of the sequence of averages does not change going from Secretory to PS).",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/by-forming-clots-in-tumors-immune-cell-aids-lung-cancers-spread/
10.1373/clinchem.2012.187617,Biology_easy_270,"Overall, NASA views this study as good news so far for their plans of crewed missions to Mars.","When gut microbiomes from these mice were transplanted into germ-free mice with an intact tolllike receptor 5 (TLR5) gene, recipient mice developed similar features of the metabolic syndrome, which suggests that the intestinal microbiome was the key determinant of this disease phenotype.","One of his eyeballs swelled slightly and his telomeres, special caps on the ends of his DNA strands, also experienced long-term shortening upon return to Earth -- both are phenomena seen generally among space station astronauts. Overall, NASA views this study as good news so far for their plans of crewed missions to Mars. While a flight to Mars will expose astronauts to more radiation and longer durations of space flight, the researchers said this study is one indication that the flight itself isn't likely to permanently harm human bodies.","Mice deficient in the microbial pattern-recognition receptor TLR5 displayed hyperphagia, became obese, and developed features of the metabolic syndrome, including hypertension, hypercholesterolemia, and insulin resistance secondary to dysregulation of interleukin-1␤ signaling . When gut microbiomes from these mice were transplanted into germ-free mice with an intact tolllike receptor 5 (TLR5) gene, recipient mice developed similar features of the metabolic syndrome, which suggests that the intestinal microbiome was the key determinant of this disease phenotype. In another study, TLR2-deficient mice developed obesity, insulin resistance, and glucose intolerance, and the gut microbiomes of TLR2-deficient mice had a greater abundance of Firmicutes and fewer Actinobacteria of the genus Bifidobacterium .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1186/s40168-015-0071-z,Biology_easy_271,So those women make much less of the special sugar.,The absolute abundance of fecal glycans (residual milk glycans present in infant stool) were significantly higher in Low-Bif qPCR stool samples (N = 42) than in High-Bif qPCR (N = 60).,"""Bifidobacteria sort of push other bacteria out. So those women make much less of the special sugar. And they were right.","Figure 8 shows a breakdown of how fecal glycoprofiles differed between samples that were High-Bif qPCR and Low-Bif qPCR . The absolute abundance of fecal glycans (residual milk glycans present in infant stool) were significantly higher in Low-Bif qPCR stool samples (N = 42) than in High-Bif qPCR (N = 60). Significantly higher amounts of non-fucosylated neutral (p < 0.0001), fucosylated (p = 0.009), and sialylated species (p = 0.045) were left behind in the Low-Bif qPCR fecal samples, as determined in ion counts per 100 μg of stool.",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1016/j.cell.2018.04.034,Biology_easy_272,"""The prototype CDK12 mutant tumor was baseline diploid and had few arm-level copy-number aberrations except gain of 8q, but notably, hundreds of focal copy-number gains were dispersed across the gnome,"" they state.","While focal gains were present on all chromosomes within a sample, other focal events, such as high-level amplifications or deletions, were rare or absent.","In contrast, they found that CDK12-mutated mCRPC tumors exhibited a ""distinctive genomic landscape"" that was similar to that identified in a subset of ovarian cancers. ""The prototype CDK12 mutant tumor was baseline diploid and had few arm-level copy-number aberrations except gain of 8q, but notably, hundreds of focal copy-number gains were dispersed across the gnome,"" they state. ""All cases with CDK12 inactivation, and only cases with CDK12 mutation, exhibited this form of genome instability in both the metastatic and primary cohorts.""","The prototypical CDK12 mutant tumor was baseline diploid and had few arm-level copy-number aberrations except gain of 8q, but notably, hundreds of focal copy-number gains were dispersed across the genome. While focal gains were present on all chromosomes within a sample, other focal events, such as high-level amplifications or deletions, were rare or absent. CDK12 biallelic inactivation was strongly associated with this form of genomic instability (p < 0.00001, Fisher's exact test).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1038/s41467-018-04151-6,Biology_easy_273,"Her findings, published in Nature Communications, provide a new level of understanding of cellular communication and cellular 'cognition', and have potential application in a variety of areas, including new targeted cancer therapies and drug resistance.",This has important implications for the interconnections of the module with other parts of the RPA-capable network.,"Her findings, published in Nature Communications, provide a new level of understanding of cellular communication and cellular 'cognition', and have potential application in a variety of areas, including new targeted cancer therapies and drug resistance. ""My research is giving us a new way to look at unravelling network complexity in nature."" ""An example of perfect adaptation is our sense of smell,"" she said.","The single independent regulator of each opposer node, and its dependents (all marked in green) do exhibit the RPA property. This has important implications for the interconnections of the module with other parts of the RPA-capable network. The symbol S N indicates that any motif or sub-network may be fully embedded at the indicated position.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BUs3tnStd9A/
10.1002/emmm.201302567,Biology_easy_274,"Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views).","Therefore, the reduction in IGF1 and IGFALS would account for the observed low levels of circulating IGF1 (Fig 5; Sjogren et al, 1999) .","Using TSUNAMI, Dr. Krainer's team induced various pathologies characteristic of Type IV (adult) SMA. Compared with healthy tissue on the left, the sample on the right shows both a reduced number of motor neurons and shrinkage of those that are present (the neurons are stained brownish-yellow in these views). (click to enlarge)

Many SMA patients do reach adulthood, however, and on occasion people develop symptoms of the illness only after they have become adults.","Most of the circulating IGF1 is in the form of stable complexes with IGFALS and IGFBP3 . Therefore, the reduction in IGF1 and IGFALS would account for the observed low levels of circulating IGF1 (Fig 5; Sjogren et al, 1999) . These liver pathologies must be a consequence of hepatic SMN2 missplicing, because they were prevented by subsequent IP injection of splicing-correcting ASO-10-27 (Supporting Information Fig S5) .",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1038/srep01456,Biology_easy_275,"The bedbugs we have now seem to be the fittest of the fit, the most resistant to whatever we throw at them; scientific testing shows pesticide bombs don't work, and neither do sonic devices.","The length of the contigs varied from 100 bp to 8,249 bp with an average length of 850 bp (Fig.","The bedbugs we have now seem to be the fittest of the fit, the most resistant to whatever we throw at them; scientific testing shows pesticide bombs don't work, and neither do sonic devices. But, if we can unravel the bedbug's strategy for combating poisons, perhaps we can create poisons that can penetrate their frustratingly thick shells. ""The surprise discovery we never expected is that most of the genes responsible for pesticide resistance in the bedbug are active in its outer skin-like shell or cuticle,"" Zhu said in a statement.","These data resulted in a total of 2,197,566 aligned reads constituting 756,568,733 bases producing 129,294 ESTs (25,935 contigs and 103,359 singletons). The length of the contigs varied from 100 bp to 8,249 bp with an average length of 850 bp (Fig. The length of singletons ranged from 50 bp to 511 bp with an average length of 261 bp (Fig.",[1],Biology,train,1.0,news,http://www.ibtimes.com/bedbugs-foil-pesticides-special-adaptations-their-armor-1403721
10.3892/ijmm.2011.724,Biology_easy_276,"Go bananas

When in doubt, reaching for a banana first thing in the morning might be just what the doctor ordered.",We also demonstrated that the mineral content of the sap prevents or improves alcohol hangover symptoms.,"Your body will like the carbs anyway. Go bananas

When in doubt, reaching for a banana first thing in the morning might be just what the doctor ordered. ""Eating a banana will replenish lost potassium after drinking too much alcohol,"" says Fuchs.","The levels of calcium, magnesium, and potassium ions were 37-, 3.9-and 16-fold higher in the A. okamotoanum sap than in commercial spring water. We also demonstrated that the mineral content of the sap prevents or improves alcohol hangover symptoms. A. okamotoanum sap may maintain the acid-base balance by supplementing electrolytes and minerals into the intestine, and may suppress extreme dehydration and tiredness.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38074943064&p=1pl&v=1&x=2b4yyZTVq7IsxuRn7mTrKw
10.1098/rsos.171474,Biology_easy_277,"""But really we should be looking at other things - maybe it is frustrations, maybe it is family or life circumstance - that we should be spending more time on.""","Said differently, this work depends on children and young people accurately reporting on their video game play, the level of violent content present in this play and their own trait-or state-level aggression (for an exception, see ).","""There are some effects of gender and some people who are from different life backgrounds have higher or lower ratings, but video game play didn't really seem to matter here."" Prof Przybylski said: ""Violent games don't seem to drive aggressive behaviour in young people. ""But really we should be looking at other things - maybe it is frustrations, maybe it is family or life circumstance - that we should be spending more time on.""","This flexibility, described as part of the 'garden of forking paths problem' increases the chance of false-positive results and serves to reduce our confidence in the inferences linking gaming to aggression . Said differently, this work depends on children and young people accurately reporting on their video game play, the level of violent content present in this play and their own trait-or state-level aggression (for an exception, see ). Mischievous responding can have the effect of introducing measurement noise that inflates relations that are logically incoherent or absurd to take at face value.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38521227375&p=1pl&v=1&x=Xvdn1eKXZPCfOlSJzuRiMg
10.1038/s41467-018-04408-0,Biology_easy_279,"If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent.",Other αand β-adrenergic and dopaminergic receptors were found at lower levels and therefore were not likely expressed ( Fig.,"Basically, the study found that there is a critical protein called BAFF, which makes B cells (a type of lymphocyte that releases harmful antibodies) more viable. If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent. Recognition of the link between testosterone and BAFF is completely new.",6a ). Other αand β-adrenergic and dopaminergic receptors were found at lower levels and therefore were not likely expressed ( Fig. 6a ).,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34230456675&p=1pl&v=1&x=lt6z2jq1xfFKoXvXclXMKg
10.1002/ece3.3060,Biology_easy_280,"For those concerned with managing salamander populations as a means of managing forests, the study serves as a reminder that not all salamander species are alike.","From an evolutionary standpoint, the observed differences in dispersal distances and genetic structure between fall breeding and spring breeding species may be a result of the trade-off between larval period length and size at metamorphosis .","""Practically, what this says is that landscape variables are not quite as important as the timing of the breeding season."" For those concerned with managing salamander populations as a means of managing forests, the study serves as a reminder that not all salamander species are alike. ""When using a particular species as a way of managing forests, conservationists should be aware of traits specific to those species, including their breeding seasons.""","Similarly, observed that the fall breeding A. opacum has stronger genetic differentiation than A. maculatum among the same ponds in Massachusetts. From an evolutionary standpoint, the observed differences in dispersal distances and genetic structure between fall breeding and spring breeding species may be a result of the trade-off between larval period length and size at metamorphosis . Organisms with longer larval periods are able to reach a larger size at metamorphosis, a relationship that is directly linked to fitness and size at first reproduction , but they are able to utilize fewer breeding habitats in a given landscape (i.e., limited to more permanent ponds).",[1],Biology,train,1.0,news,http://www.futurity.org/salamanders-breeding-1515412-2/
10.1038/s41467-019-09863-x,Biology_easy_281,"Such measures include widespread adoption of renewable energies such as solar power, the study said.","The nonlinear correction to the SAF leads to small but statistically significant increases in C NPV for Zero Emissions and 1.5°C, 2.0°C and 2.5°C target scenarios, statistically significant decreases in C NPV for NDCs Partial and BaU, and is not significant for NDCs (all at the 5% level).","""Our findings support the need for more proactive mitigation measures to keep global temperature rise well below 2degC,"" Yumashev said in a statement. Such measures include widespread adoption of renewable energies such as solar power, the study said. The economic growth of warmer nations such as Sudan, India, Nigeria, and Brazil has been stunted by about 25-36 percent due to climate change, the study found.","The nonlinear PCF leads to statistically significant increases in C NPV at the 5% significance level for all the scenarios considered, especially the NDC and BaU. The nonlinear correction to the SAF leads to small but statistically significant increases in C NPV for Zero Emissions and 1.5°C, 2.0°C and 2.5°C target scenarios, statistically significant decreases in C NPV for NDCs Partial and BaU, and is not significant for NDCs (all at the 5% level). When the nonlinear PCF and SAF representations are combined, the statistical mean of the economic effect of climate change increases relative to the base estimate with the legacy PCF and SAF by $16.1 trillion (1 trillion = 10 12 ) for the counterfactual Zero Emissions scenario ($1288 trillion base estimate), $24.8 trillion for 1.5°C target ($613 trillion base estimate), $33.8 trillion for 2.0°C target ($613 trillion base estimate), $50.3 trillion for 2.5°C target ($815 trillion base estimate), $66.9 trillion for NDCs ($1390 trillion base estimate), and by $59.8 trillion for NDCs Partial ($1702 trillion base estimate).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39060991235&p=1pl&v=1&x=NDKVR8asOZZqfp2_RfPJyQ
10.1080/10635150701775111,Biology_easy_282,"It shows our method is pretty robust.""","nov. (6 localities) are omission error = 4 of six, and P < 0.001 for all replicates.","All results were consistent. It shows our method is pretty robust."" When asked what could be done to gather more evidence to support their hypothesis, Zink admitted that the fluctuation hypothesis is part speculation.","Jackknife validation statistics for the western coastal P. dubia (12 localities) are omission error = 2 of 12, and P < 0.001 for all replicates. nov. (6 localities) are omission error = 4 of six, and P < 0.001 for all replicates. The P. hielscheri locality sample size (three) was too small for validation.",[1],Biology,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1093/molbev/msu227,Biology_easy_284,"""One of the most surprising findings is that a similar mode of evolution has so far only been observed in fungi, plants, and animals.""",Another conceivable scenario might be that selection pressure for increased gene dosage has contributed to the expansion of the large chlamydial gene families.,"The authors argue that the evolutionary forces at work behind the diversity of chlamydiae are the result of a unique confluence of birth and death gene evolutionary cycles. ""One of the most surprising findings is that a similar mode of evolution has so far only been observed in fungi, plants, and animals."" Such factors can provide the research community with new clues into how chlamydia has emerged as a human scourge, as well as novel targets for next-generation therapeutics.","However, the failure to detect positive selection as the major force acting on the PEX and NEX gene family members casts doubts on a coevolutionary arms race as the sole mechanism for the evolution of these gene families. Another conceivable scenario might be that selection pressure for increased gene dosage has contributed to the expansion of the large chlamydial gene families. In reduced genomes where the pool of regulatory proteins is limited, a path for increased protein expression might be gene duplication.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141014085130.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04627-5,Biology_easy_285,"The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said.","Over the course of the intervention, only the posterior CC retained a relationship to Reading Skill.","For the few children who showed no significant decline in diffusion by MRI, Yeatman said there could be compounding differences in individual capacities for brain plasticity, age of the participants (younger brains may be more susceptible to change than slightly older ones) or other factors. The callosal connections showed no changes between treatment and control groups, results that support past research suggesting that this structure, though relevant for reading acquisition, may already be mature and stable by age 7, Yeatman said. Just what kind of tissue was created among reading program participants is likely to be the subject of future study, the authors said.","Anatomy-behavior correlations depend on recent experience. Over the course of the intervention, only the posterior CC retained a relationship to Reading Skill. In contrast, as MD values declined in the AF and ILF, the instantaneous, cross-sectional correlation between reading and MD changed between sessions, as indicated by a significant interaction between MD and session in predicting Reading Skill for the intervention group (linear mixed effects model predicting Reading Skill from MD, session, and their interaction, with a random effect of subject, see Table 4 , there was no statistical difference in variance across sessions (indeed, variances were nearly matched; see also Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34305651947&p=1pl&v=1&x=5K-kiFIe9C-USZImgR7dwA
10.1098/rspb.2018.0761,Biology_easy_286,"It's physiologically demanding, and the stakes are high: the success of the colony depends on a queen's solitary work during this time.","Here, we demonstrate that sublethal exposure to imidacloprid, a widely used neonicotinoid-type insecticide, has a broad suite of negative effects on early-nesting bumblebee queens.","It's physiologically demanding, and the stakes are high: the success of the colony depends on a queen's solitary work during this time. Led by Hollis Woodard, an assistant professor of entomology, the team found that exposure to a widely used insecticide and a poor diet negatively impacted bumblebee queens' health and work, which could have dramatic consequences on an already dwindling pollinator group. They showed bumblebee queens were far less active and six times more likely to die during sustained exposure (37 days) to the pesticide, which could be somewhat mitigated by a shorter exposure of 17 days.","Pollen diet was not an important driver of brood production overall, but among untreated queens, those fed monofloral Cistus pollen had significantly fewer larvae and pupae than queens fed mixed-source or monofloral Erica pollen ( p , 0.03 for counts of larvae and pupae). Here, we demonstrate that sublethal exposure to imidacloprid, a widely used neonicotinoid-type insecticide, has a broad suite of negative effects on early-nesting bumblebee queens. These effects were observed at the level of individual queens, who were less active and exhibited greater mortality when exposed to imidacloprid, but also at the colony level, where numbers of brood in the nest were dramatically reduced in treated queens, particularly when queens experienced sustained exposure to the insecticide.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ea2TPwN3kfM/
10.1080/10635150701775111,Biology_easy_287,Three of the specimens yielded enough usable genome sequences to analyze the population size through a complicated algorithm.,nov. that includes the type locality (compare Figs.,"They knew that such fluctuations could dramatically reduce population size, and perhaps human exploitation through hunting and trade may have tipped the balance at the wrong time for this species, which could never recover. Three of the specimens yielded enough usable genome sequences to analyze the population size through a complicated algorithm. ""By analyzing the pattern, it gives you an inference whether the population was stable, increasing, decreasing, or, what we thought, oscillating,"" Zink said.","The P. modesta niche model includes a disjunct unoccupied area north of its actual distribution, which corresponds closely to the southern distribution of P. ravenala sp. nov. that includes the type locality (compare Figs. Despite these advances, one of the remaining challenges with the species delimitation approach that we present here concerns the assessment of the ecological niche model quality in the lumped vs. split species complexes.",[1],Biology,train,1.0,news,http://arstechnica.com/science/2014/06/humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.1080/10635150701775111,Biology_easy_288,"Humans Not Entirely at Fault for Passenger Pigeon Extinction

Once the most numerous bird species in North America, passenger pigeons went from numbering in the billions to being extinct in less than a century.","However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself.","Humans Not Entirely at Fault for Passenger Pigeon Extinction

Once the most numerous bird species in North America, passenger pigeons went from numbering in the billions to being extinct in less than a century. Flocks could block the sunlight for hours as they moved in mind-boggling numbers. Their excrement was toxic to plants and when a flock roosted on trees, they could break all the branches through the sheer numbers perching.""","Our preliminary analysis based on 12S mtDNA (not shown) finds the Zanzibar specimen falling in a clade with P. ravenala and the other Comoros specimens forming a polytomy with P. dubia from Northwest Madagascar. However, the inclusion of many more species is needed to explore the full biogeographic history of this group, especially concerning continental speciation within Madagascar itself. Nevertheless, based on the findings of this study, we anticipate that this new application of ecological niche modeling will greatly facilitate species delimitation, and thus also aid the recognition of both additional species diversity and more recent speciation events.",[1],Biology,train,1.0,news,http://www.theepochtimes.com/n3/753700-humans-not-entirely-at-fault-for-passenger-pigeon-extinction/
10.3945/jn.113.188441,Biology_easy_289,"The researchers found that eating instant noodles two or more times a week was associated with cardio-metabolic syndrome, which raises a person's likelihood of developing heart disease and other conditions, such as diabetes and stroke.",Differences were small in protein and fat intake between participants in the highest quintile of the MP and participants in the highest quintile of the TP.,"The researchers found that eating instant noodles two or more times a week was associated with cardio-metabolic syndrome, which raises a person's likelihood of developing heart disease and other conditions, such as diabetes and stroke. Difference in obesity and metabolic syndrome components may also have a role to play. ""This research is significant since many people are consuming instant noodles without knowing possible health risks,"" Dr. Shin said.","Those with the highest quintiles of the MP also had a higher frequency of instant noodle intake (a mean of 2 times/wk in men and 1.2 times/wk in women) compared with the highest quintiles of the TP (a mean of 1.1 times/wk in men and 0.7 times/wk in women) (Table 1) . Differences were small in protein and fat intake between participants in the highest quintile of the MP and participants in the highest quintile of the TP. In addition, the mean sodium intake was very high across all categories (age-standardized mean sodium intake: 6.0 g in men, 4.2 g in women).",[1],Biology,train,1.0,news,http://www.hngn.com/articles/38940/20140813/instant-noodles-increase-risk-heart-disease-diabetes-stroke.htm
10.1098/rsos.171474,Biology_easy_291,"Prof Przybylski said: ""Violent games don't seem to drive aggressive behaviour in young people.","By doing so, the research provides a template that media effects researchers could follow when adopting a hypothesis testing approach with other important and plausible forms of technology influence.","""There are some effects of gender and some people who are from different life backgrounds have higher or lower ratings, but video game play didn't really seem to matter here."" Prof Przybylski said: ""Violent games don't seem to drive aggressive behaviour in young people. ""But really we should be looking at other things - maybe it is frustrations, maybe it is family or life circumstance - that we should be spending more time on.""","Our study, then, contributes to this literature base, as we prespecified exactly how we would operationalize key variables before conducting the study. By doing so, the research provides a template that media effects researchers could follow when adopting a hypothesis testing approach with other important and plausible forms of technology influence. Findings can be interpreted with greater confidence because these standards were set for type 1 and 2 error control and the sample was sufficiently large for a fair and sensitive test of the null and alternative hypotheses.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38521227375&p=1pl&v=1&x=Xvdn1eKXZPCfOlSJzuRiMg
10.1016/j.neuron.2018.12.026,Biology_easy_293,Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.,"Thus, firing correlations were decreased or unchanged in ASD mutants.","Note: material may have been edited for length and content. For further information, please contact the cited source. Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.","Fmr1 À/y and Cntnap2 À/À mice showed a similar tendency for reduced firing synchrony versus WTs, but this was significant only for Fmr1 À/y mice (Fmr1 +/y versus Fmr1 À/y , p = 0.00027; Cntnap2 +/+ versus Cntnap2 À/À , p = 0.07; 16p11.2 +/+ versus 16p11.2 del/+ , p = 0.49, permutation test) ( Figure 6J ). Thus, firing correlations were decreased or unchanged in ASD mutants. Sensory gain between L4 and L2/3 in vivo may parallel the functional strength of L4-L2/3 feedforward PSPs in vitro.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38318437455&p=1pl&v=1&x=tFlh-_qIVNCNf8CEol-uvQ
10.1073/pnas.1704745114,Biology_easy_295,"The mathematical theory describing the brain's function predicted that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, than to constant environments.","5Z ), the transcript is abundant in this developmental state .","The separation of these parts in the seed 'brain' also appears to be central to how it functions.' The mathematical theory describing the brain's function predicted that more seeds would germinate when exposed to varying environments, such as fluctuating temperatures, than to constant environments. The scientists tested this theory in the lab and found exactly this behaviour.","Despite the activity of this promoter not being detected in primary dormant seeds (SI Appendix, Supplementary Fig. 5Z ), the transcript is abundant in this developmental state . The radicle-enriched localization of decision-making components occurred during late seed development, coincident with the temporal induction of dormancy in Arabidopsis seeds during seed maturation (SI Appendix, Supplementary Fig.",[1],Biology,train,1.0,news,http://www.seeddaily.com/reports/Scientists_discover_plant_brain_controlling_seed_development_999.html
10.1177/1535370219829006,Biology_easy_297,"These studies also define a true physiological environment that can be used to study valve function as well as discover new drugs for preventing, slowing or reversing valve disease.","A transcriptomics study of valvular cells experiencing variable stiffness also identified similar results where some ECM proteins, including fibrillin 1, are upregulated and some are downregulated with VIC activation.","Collectively, these studies provide new insights regarding the molecular mechanisms that regulate heart valve response to mechanical stress. These studies also define a true physiological environment that can be used to study valve function as well as discover new drugs for preventing, slowing or reversing valve disease. Dr. Lacerda said that ""Development of in vitro models to properly guide design of replacement tissues is key for the advancement of tissue engineering techniques.","The synthesis of these proteins could be the first response to loss of basement membrane by VICs. A transcriptomics study of valvular cells experiencing variable stiffness also identified similar results where some ECM proteins, including fibrillin 1, are upregulated and some are downregulated with VIC activation. Fibrillin 1 also plays crucial role in regulating cytokine signaling.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38770512405&p=1pl&v=1&x=WYLJzBjhCC8lOi2zfIIFGg
10.1016/j.cell.2013.08.004,Biology_easy_298,"""The study proposes that the light-stimulated production of SIK1 in turn switches off the molecular pathway that feeds into the clock mechanism, thereby halting the shifting response of the biological clock,"" the researchers wrote.",The rhythms of SCN treated with I3M peaked approximately 1 hr later than DMSO-treated controls ( Figure 3F ).,"The mice were found to adjust more quickly to the changes in the daily patterns of light and dark that were set to resemble those of a time zone change. ""The study proposes that the light-stimulated production of SIK1 in turn switches off the molecular pathway that feeds into the clock mechanism, thereby halting the shifting response of the biological clock,"" the researchers wrote. Overall, the researchers found that the SIK1 protein delays the body clock's shifting response to time changes, and therefore causes complications for travelers and shift workers.","We observed a 10.90 ± 1.02 hr phase delay of the PER2::LUC rhythm in I3M-treated cells, compared with 7.59 ± 1.00 hr delay in the control, a difference of 3.3 hr ( Figures 3D and 3E) . The rhythms of SCN treated with I3M peaked approximately 1 hr later than DMSO-treated controls ( Figure 3F ). It should be noted that I3M is a nonspecific inhibitor of SIK1, and although directly inhibiting SIK1 ( Figure 3A) , its targets also include the kinase GSK3B, which has a role in the circadian clock ) .",[1],Biology,train,1.0,news,http://www.medicaldaily.com/jet-lag-cure-could-lie-newly-discovered-gene-255200
10.1038/s41589-018-0155-8,Biology_easy_299,"The researchers found that ABHD12 normally acts as a powerful ""brake"" on the immune system to keep it from becoming harmfully overactive.","DO264-treated mice, however, show minimal impairment in auditory function following four weeks of drug exposure.","The researchers found that ABHD12 normally acts as a powerful ""brake"" on the immune system to keep it from becoming harmfully overactive. Mice engineered without the protein have signs of elevated inflammation, and their immune systems are more likely to overreact to a viral infection. The discovery suggests that the absence of ABHD12 in people with mutant versions of its gene may cause neurological disease at least in part via excessive immune activity.","Mice treated with DO264 display dosedependent increases in brain lyso-PS and 20:4 PS content that are qualitatively similar to the changes observed in ABHD12 -/mice. DO264-treated mice, however, show minimal impairment in auditory function following four weeks of drug exposure. We also found that DO264 elevated the lyso-PS and 20:4 PS content of primary human macrophages.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1098/rstb.2008.0288,Biology_easy_302,"""Maybe they only appeared quite some time after the trainees qualified.","Finally, it will also be vital to consider whether expertise and its related effects can be expected to develop in any individual or whether they are genetically determined.","Maguire says she was ""greatly relieved"" by the results of her study, which appears in the December issue of Current Biology. ""Maybe they only appeared quite some time after the trainees qualified. But we found them within the five years it took to do the study.""","Clearly, more work is required to establish whether the effects we have described here in relation to taxi drivers generalize beyond the domain of memory and the hippocampus. In particular, longitudinal studies will be crucial to explore the nature and consequences of skill acquisition. Finally, it will also be vital to consider whether expertise and its related effects can be expected to develop in any individual or whether they are genetically determined.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=london-taxi-memory
10.1101/gad.263707.115,Biology_easy_304,"""In this study, we found that a type of abnormal transcription dramatically increases in aged cells and that its reduction can prolong lifespan,"" said Dang, who initiated this line of research while working in Berger's laboratory.","However, relative enrichment changes of young fractions compared with the fraction prior to the overnight culturing were affected only by doubling time.","""In this study, we found that a type of abnormal transcription dramatically increases in aged cells and that its reduction can prolong lifespan,"" said Dang, who initiated this line of research while working in Berger's laboratory. This is the first demonstration that such a mechanism exists to regulate aging."" ""We used budding yeast, a single-cell organism, to study the epigenetic regulation of aging and this simple model turned out to be quite powerful,"" explained Sen.","Both doubling time and replicative life span may affect S4O relative enrichment. However, relative enrichment changes of young fractions compared with the fraction prior to the overnight culturing were affected only by doubling time. This growth effect on S4O relative enrichment was considered only for mutants with an estimated doubling time 20% different from that of the wild type.",[1],Biology,train,1.0,news,http://www.newswise.com/articles/cell-aging-slowed-by-putting-brakes-on-noisy-transcription
10.1038/ncomms4999,Biology_easy_305,"Any shorter, and biochemical reactions would become inefficient as energy is drained from the system too quickly.",Methods OKE experimental details.,"The experiments show that the ringing motion lasts for only a picosecond or one millionth of a millionth of a second. Any shorter, and biochemical reactions would become inefficient as energy is drained from the system too quickly. Any longer and the enzyme would simple oscillate forever: react, unreact, react, unreact, etc.",It seems likely that proteins have evolved such underdamped vibrational motions by providing an interaction site which is pre-organized 44 in order to arrive at the optimal degree of damping for efficient biochemical reactivity and function. Methods OKE experimental details. Stretching the pulse enables a higher energy to be used without sample damage or nonlinear effects and reduces the upper bandwidth limit allowing large step size scanning without introducing undersampling artefacts 45 .,[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140603092424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1126/sciadv.1500472,Biology_easy_306,"Research Assistant Professor in Genetics at Trinity, Dr Matthew Campbell, added: aEURoeOur recent findings have highlighted the importance of understanding diseases at the molecular level.",Immunocytochemical analysis of claudin-5 and occludin localization showed a decrease in the punctate staining of both proteins 6 and 12 hours after treatment with Ab(1-40) monomers and dimers (Fig.,"We think that this alteration could be an entrained mechanism to allow for the clearance of toxic amyloid-beta from the brain in those living with AlzheimeraEUR(tm)s disease,aEUR said postdoctoral researcher in TrinityaEUR(tm)s School of Genetics and Microbiology, Dr James Keaney, who spearheaded the study. Research Assistant Professor in Genetics at Trinity, Dr Matthew Campbell, added: aEURoeOur recent findings have highlighted the importance of understanding diseases at the molecular level. The concept of periodic clearance of brain amyloid-beta across the BBB could hold tremendous potential for AlzheimeraEUR(tm)s patients in the future.","Whereas the addition of Ab(1-40) monomers and dimers caused a transient and reversible decrease in claudin-5 and occludin, there was an apparent rebound up-regulation of both occludin and ZO-1, 24 and 48 hours after treatment (Fig. Immunocytochemical analysis of claudin-5 and occludin localization showed a decrease in the punctate staining of both proteins 6 and 12 hours after treatment with Ab(1-40) monomers and dimers (Fig. This was a transient response, with the protein levels returning to baseline 48 hours after treatment (Fig.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/trinity-researchers-report-major-breakthrough-in-understanding-alzheimers-disease/
10.1534/genetics.116.197285,Biology_easy_307,"""If you don't, NHEJ is going to screw things up because it creates resistance alleles,"" Unckless said.","We expect that in many intended target systems for CGD, such as mosquitoes, these conditions are typically exceeded.","For a CRISPR/Cas9 gene drive to be most effective, it must be ""tuned"" toward homology-directed repair. ""If you don't, NHEJ is going to screw things up because it creates resistance alleles,"" Unckless said. The researchers conclude that, like other attempts to manipulate populations, gene drive is likely to lead to resistance alleles.","Resistance is generally likely to evolve whenever either θ > 0.1, or N e δ > 1, as long as resistance alleles provide any fitness advantage over the driver and driver costs are not completely dominant. We expect that in many intended target systems for CGD, such as mosquitoes, these conditions are typically exceeded. Estimates of single nucleotide mutation rates tend to be on the order of -9 - -8 in such species 18-20 and a single mutation in the PAM motif suffices to create a resistance allele .",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1073/pnas.1601081113,Biology_easy_308,"Rather than continuous forest, the results suggest that for roughly two million years before humans arrived, the center of the island was a patchwork of grasslands interspersed with woodlands and shrubs that served as a transition zone between the lush rainforests of the east and the dry forests of the west.","This biogeographic barrier is further emphasized given that the M. myoxinus dots are pulled northward and M. berthae dots pushed southward, opposite of what would be expected in the presence of gene flow between these two species.","The new findings add to a growing body of research that is beginning to rethink this view. Rather than continuous forest, the results suggest that for roughly two million years before humans arrived, the center of the island was a patchwork of grasslands interspersed with woodlands and shrubs that served as a transition zone between the lush rainforests of the east and the dry forests of the west. ""Madagascar wasn't completely covered by forests when humans arrived,"" Yoder says.","Instead, there is a strong separation of M. myoxinus and M. berthae, consistent with the biogeographic separation of these species by the Tsiribihina River, suggesting that the river is a significant barrier to gene flow. This biogeographic barrier is further emphasized given that the M. myoxinus dots are pulled northward and M. berthae dots pushed southward, opposite of what would be expected in the presence of gene flow between these two species. There is also a strong geogenetic signal regarding the inference of ancestral habitat type in the Central Highlands.",[1],Biology,train,1.0,news,http://www.futurity.org/lemurs-madagascar-forests-1207872-2/
10.1073/pnas.1511220112,Biology_easy_309,"""These changes in the shoulder, which were probably initially driven by the use of tools well back into human evolution, also made us great throwers,"" Roach said.","Moreover, the likelihood of these alternative hypotheses can be directly tested using the better characterized later hominin fossil record.","""The mix of ape and human features observed in A. afarensis' shoulder support the notion that, while bipedal, the species engaged in tree climbing and wielded stone tools. ""These changes in the shoulder, which were probably initially driven by the use of tools well back into human evolution, also made us great throwers,"" Roach said. ""Our unique throwing ability likely helped our ancestors hunt and protect themselves, turning our species into the most dominant predators on earth.""","This mix of character states raises the question of whether modern human morphology reflects evolution from a more derived African ape morphology or retention of primitive traits from an earlier ape ancestor. Moreover, the likelihood of these alternative hypotheses can be directly tested using the better characterized later hominin fossil record. Specifically, given alternative ancestral conditions, one can model the associated evolutionary trajectories and intermediate states connecting them to the descendant populations and test how well these predictions fit the available fossil evidence.",[1],Biology,train,1.0,news,http://www.technology.org/2015/09/09/shouldering-burden-evolution/
10.1016/j.cell.2013.08.004,Biology_easy_311,"""Such drugs could potentially have broader therapeutic value for people with mental health issues.""","Cells treated with I3M peak significantly later than DMSO-treated controls (one-way ANOVA; p < 0.01, with post hoc t tests, *p < 0.05).","When they blocked the activity of SIK1, the mice adjusted faster to changes in light cycle. Dr. Russell Foster said that we were still a long way off from a jet lag cure, but added it was a step towards developing drugs for interrupted sleep cycles. ""Such drugs could potentially have broader therapeutic value for people with mental health issues.""","In contrast to these kinases, SIK1 does not target the core clock proteins to control their degradation; rather, it attenuates the induction of clock genes in response to entraining stimuli, functioning as a negative-feedback mechanism to deactivate the molecular pathways that are activated following a phase-shifting stimulus. Cells treated with I3M peak significantly later than DMSO-treated controls (one-way ANOVA; p < 0.01, with post hoc t tests, *p < 0.05). the circadian system is no exception.",[1],Biology,train,1.0,news,http://www.businessinsider.com/cure-for-jet-lag-2013-8
10.1016/j.cell.2018.04.034,Biology_easy_312,"They identified CDK12 mutations in 25/360 mCRPC patients (6.9%), but in only 6/498 patients with primary prostate cancer.","We detected aberrations of CDK12 in 25/360 of mCRPC patients (6.9%), 95% confidence interval (CI) [4.6%, 10 .2%] ( Figure 1A ).","This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy."" They identified CDK12 mutations in 25/360 mCRPC patients (6.9%), but in only 6/498 patients with primary prostate cancer. ""All patients showed biallelic inactivation of CDK12,"" they note, while ""strikingly,"" the CDK12 mutations were mutually exclusive to all of the already known primary genetic drivers (PGDs) analysed, including ETS fusions, SPOP mutations, HRD (homologous recombination-deficiency, ATM mutations and mismatch repair-deficiency (MMRD).""","Further, we identify that CDK12 mutant tumors have synthetic genetic dependencies and a characteristic immunophenotype, which provide candidate targets for precision therapy. We detected aberrations of CDK12 in 25/360 of mCRPC patients (6.9%), 95% confidence interval (CI) [4.6%, 10 .2%] ( Figure 1A ). This is significantly higher than in primary PCa, 6/498 patients (1.2%) ( Figure 1B ; Table S3 ) (p < 0.0001 Fisher's exact test).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1098/rsos.171474,Biology_easy_313,"Hate has no place in America.""",It is possible that the retrospective month-long 'snap shot' this study uses missed a critical dynamic which develops over repeated engagement with video games.,"These sinister ideologies must be defeated. Hate has no place in America."" ""When you dehumanize your opponents, whether Democrats, the news, immigrants, people of faith, of different faiths, you're running the risk of someone taking your words and acting upon it.""","This could provide a context to understand gaming effects set against a rich data milieu, including information on objective gaming behaviours, social, familial, school, individual and genetic level factors. It is possible that the retrospective month-long 'snap shot' this study uses missed a critical dynamic which develops over repeated engagement with video games. To this end, field or natural experiments using multi-wave random-intercepts cross-lagged panel modelling should follow the present work to provide an expanded test of the effects of violent gaming on human behaviour.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39881272230&p=1pl&v=1&x=agjUuQHKttCmyqc0lNUvPA
10.1073/pnas.1704745114,Biology_easy_314,This decision-making center is similar to an analogous mechanism in human brains.,"Fluctuating inputs therefore act as an instructive signal for seeds, enhancing the accuracy with which plants are established in ecosystems, and distributed computation within the radicle underlies this signal integration mechanism.",Plants may be smarter than we thought. This decision-making center is similar to an analogous mechanism in human brains. The hormones that activate movement in the plant (in the case of germination) are similar to the decision-making center involved in movement in human brains.,"The responses to both GA and ABA were found to occur within distinct cell types, suggesting cross-talk occurs at the level of hormone transport between these signaling centers. Fluctuating inputs therefore act as an instructive signal for seeds, enhancing the accuracy with which plants are established in ecosystems, and distributed computation within the radicle underlies this signal integration mechanism. seed | dormancy | signal integration | distributed control | variability P lant development is guided by the perception of diverse environmental cues and their integration into key transitions (1).",[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/38372/20170609/scientists-germinate-brain-plant-crops.htm
10.1016/j.neuron.2014.04.039,Biology_easy_315,"Because of the similarities between the two, it only makes sense that smoking pot might be able to reverse beta-amyloid's negative effects on endocannabinoids and go on to prevent Alzheimer's, right?","Tetanic stimulations that are strong enough to overcome the intact synaptic inhibition will induce full strength LTP, despite the presence of Ab.","Because of the similarities between the two, it only makes sense that smoking pot might be able to reverse beta-amyloid's negative effects on endocannabinoids and go on to prevent Alzheimer's, right? ""Exposure to marijuana over minutes or hours is different: More like enhancing everything indiscriminately, so you lose the filtering effect. It is key, then, to your ability to learn and remember that these short-acting and precisely-timed endocannabinoid bursts fire only when a signal is truly worthy of attention.","As such, any effects that Ab may have on the induction of E-S potentiation or LTP are indirect. Tetanic stimulations that are strong enough to overcome the intact synaptic inhibition will induce full strength LTP, despite the presence of Ab. Weaker induction protocols will produce LTP that appears to be Ab-sensitive, because those weaker protocols cannot produce the sufficient postsynaptic depolarization that LTP induction requires in the face of intact synaptic inhibition.",[1],Biology,train,1.0,news,http://www.medicaldaily.com/if-blocked-endocannabinoids-trigger-dementia-symptoms-could-cannabis-prevent-alzheimers-288806
10.1016/j.cmet.2015.02.003,Biology_easy_316,"Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal molecules than those that grew in a culture medium without salt.",These findings suggest that immune cells entering wounded skin are exposed to a hypertonic interstitial microenvironment.,"Titze and his colleagues realized that immune cells arriving in wounded skin to fight infections were entering a salty microenvironment. Salt increased the microbe-killing capacity of the immune cells, the team reports; the macrophages exposed to high levels of sodium chloride released significantly more microbicidal molecules than those that grew in a culture medium without salt. After 24 hours, the E. coli load in macrophages exposed to high sodium chloride levels was less than half of that of macrophages cultured without salt, and L. major infections were down as well.","Infected mouse skin displayed $40 mmol/l increase in (Na + +K + )-to-water ratio, compared to plasma levels ( Figure 1D ). These findings suggest that immune cells entering wounded skin are exposed to a hypertonic interstitial microenvironment. A 40 mM increase in culture medium NaCl concentration (HS) boosted LPS-triggered induction of Nos2 on mRNA and protein level with enhanced NO release in RAW 264.7 MF and bone-marrow-derived MF (BMM) (Figure 2A ).",[1],Biology,train,1.0,news,http://news.sciencemag.org/biology/2015/03/does-high-salt-diet-combat-infections
10.1038/ncomms5060,Biology_easy_317,"(Image: Forschungszentrum Julich) (click on image to enlarge)

In our cells, which contain biopolymer filaments, active flow due to molecular motor proteins can be observed.",Western blotting with anti-Protein C antibody detected a single protein band of the expected molecular mass (Fig.,"This finding may explain how other biological as well as man-made filaments flow, which could aid, among other things, the search for renewable alternatives to replace oil-based polymers. (Image: Forschungszentrum Julich) (click on image to enlarge)

In our cells, which contain biopolymer filaments, active flow due to molecular motor proteins can be observed. The viscosity of solutions of semiflexible polymers decreases dramatically at high shear rates a measure of the velocity gradient or the speed differences within a fluid.","Similarly, RNAi of another inner-arm dynein, DNAH10, in procyclic trypanosomes also caused severe motility defect, but did not disrupt axoneme structure . Western blotting with anti-Protein C antibody detected a single protein band of the expected molecular mass (Fig. 3A) , and immunostaining with anti-Protein A antibody confirmed that PTP-tagged TbCentrin3 was correctly localized to the flagellum (See Fig.",[1],Biology,train,1.0,news,http://www.nanowerk.com/nanotechnology-news/newsid=37681.php
10.1002/emmm.201302567,Biology_easy_318,"We noted, importantly, marked liver and heart pathologies that were related to SMA's progression in adults.""","Grip strength (n ¼ 10. findings reveal that SMN function is required for a-motor neuron and NMJ maintenance even after embryonic development, although the threshold levels of SMN appear to be lower than for neonate mice, meaning that mature motor units can tolerate relatively low SMN levels.","""We observed delayed onset of motor neuron dysfunction; we noted also that SMN2 mis-splicing increases during the late stages of SMA, likely accelerating its progression in the body. We noted, importantly, marked liver and heart pathologies that were related to SMA's progression in adults."" Sahashi and Krainer added: ""Perhaps most encouraging, our mouse model suggests that only moderate levels of SMN protein are needed in the adult nervous system for normal function.","C. Improved motor function. Grip strength (n ¼ 10. findings reveal that SMN function is required for a-motor neuron and NMJ maintenance even after embryonic development, although the threshold levels of SMN appear to be lower than for neonate mice, meaning that mature motor units can tolerate relatively low SMN levels. Removal of SMN at 1 month postnatally in the SMA D7 mouse results in no impairment in synaptic transmission at NMJs, 1 month later, at a time when the mice are dying .",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/09/130909093116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13059-018-1434-0,Biology_easy_319,"""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities.""",b The d N /d S ratio for both MHC I-and MHC II-binding epitopes was significantly lower than for a randomized set of non-epitope regions.,"We demonstrate that negative selection is underestimated and acts stronger on certain regions, which are related to essential cellular functions and to immune response,"" adds Schaefer. ""Our work could be interpreted as a proof of concept; it may shed light upon mechanisms underlying immune evasion and may provide insights for improving cancer therapies in the future by revealing cancer vulnerabilities."" Interdisciplinarity and collaboration are the key success factors

This work, which has been published in Genome Biology, shows how interdisciplinary research pushes the boundaries of knowledge and contributes to finding new insights for improving health.",Such evidence suggests that tumor cells may escape immune surveillance by acquiring mutations in native non-epitope regions and that native epitope regions become depleted of any high functional impact mutation. b The d N /d S ratio for both MHC I-and MHC II-binding epitopes was significantly lower than for a randomized set of non-epitope regions. The calculation holds when analyzing specifically patients carrying the HLA-A0201 allele vs patients not carrying this allele.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34527375501&p=1pl&v=1&x=1CtmjzSbC1y6cGD8LDIXPA
10.1534/genetics.116.197285,Biology_easy_320,"The researchers conclude that, like other attempts to manipulate populations, gene drive is likely to lead to resistance alleles.","As with de novo mutation, any given resistance allele that arises as a single copy in generation t by this mechanism will successfully establish with probability ⇡(t), assuming that resistance does not arise from any other mechanism.","""If you don't, NHEJ is going to screw things up because it creates resistance alleles,"" Unckless said. The researchers conclude that, like other attempts to manipulate populations, gene drive is likely to lead to resistance alleles. However, with this known, scientists can prepare appropriately for a dynamic gene drive system with new constructs responding to the appearance of resistance alleles.","By comparison, the rate at which de novo resistance alleles arise is proportional to the overall number of wildtype alleles in the population, which is highest when the driver is introduced and decreases monotonically afterwards ( Figure 3d ). As with de novo mutation, any given resistance allele that arises as a single copy in generation t by this mechanism will successfully establish with probability ⇡(t), assuming that resistance does not arise from any other mechanism. This equation is analogous to Equation (18) for the de novo mutation scenario, except for u µ (t) being exchanged by u (t).",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1038/s41467-018-04408-0,Biology_easy_322,"Basically, the study found that there is a critical protein called BAFF, which makes B cells (a type of lymphocyte that releases harmful antibodies) more viable.","5d ), but the FRC population, defined as CD45 -CD31 -PDPN + cells, was expanded in castrated mice ( Fig.","""In this way, we can eventually provide better treatment for the diseases."" Basically, the study found that there is a critical protein called BAFF, which makes B cells (a type of lymphocyte that releases harmful antibodies) more viable. If you eliminate testosterone, you get more BAFF and thereby more B cells in the spleen because they survive to a greater extent.","The total number of CD45 − cells was unchanged in castrated mice ( Fig. 5d ), but the FRC population, defined as CD45 -CD31 -PDPN + cells, was expanded in castrated mice ( Fig. 5e , f).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34230456675&p=1pl&v=1&x=lt6z2jq1xfFKoXvXclXMKg
10.1186/s40168-015-0071-z,Biology_easy_323,"The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States.","As MALDI may not reliably distinguish between members of this group, we do not include subspecies designations in the description of the isolates.","The research may have applications in a clinical setting for protecting premature infants from a range of intestinal diseases including necrotizing enterocolitis (NEC), a condition that is the second most common cause of death among premature infants in the United States. The researchers emphasized that the finding does not suggest that breast milk from mothers without an active copy of the gene is less nourishing or healthy. Rather, it conveys the subtle and elegant choreography of one part of the human microbiome: The relationships between the mothers' genetics, the composition of her breast milk and the development of thier infants' gut microbiota.","The most commonly isolated species were B. breve and members of the B. longum group. As MALDI may not reliably distinguish between members of this group, we do not include subspecies designations in the description of the isolates. Notably, the B. longum group increased in proportional representation over time in the secretor-fed, but not in the non-secretor-fed infants.",[1],Biology,train,1.0,news,http://www.healthcanal.com/genetics-birth-defects/62224-a-mother-s-genes-can-influence-the-bacteria-in-her-baby-s-gut-researchers-at-uc-davis-have-found.html
10.1038/s41467-019-09863-x,Biology_easy_324,It's a much longer-term vision than some other estimates present--many climate change projections tend to focus on 2100 as a benchmark.,All this warrants their rigorous quantitative assessment.,"The extra costs in a 2 C world would amount to nearly $34 trillion by 2300 and would come to nearly $25 trillion under 1.5 C of warming. It's a much longer-term vision than some other estimates present--many climate change projections tend to focus on 2100 as a benchmark. ""True, we don't know exactly what society and the economy will look like 300 years in the future,"" he told E&E News.","PCF is caused by additional CO 2 and methane emissions from thawing permafrost, and SAF is mostly driven by increased solar absorption due to the decline of Arctic sea ice and land snow covers. All this warrants their rigorous quantitative assessment. The emulators allow one to study the entire parameter space, which is not possible with complex physical models, and also help establish dynamic links between highly specialized climate and economic models.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1038/s41467-018-07557-4,Biology_easy_326,"""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality.""","As we are not aware of any population projection that would match with the extent of our study area, resolution, and periods analysed, we consider that using current population counts is the safest way to address human exposure to future hazards, even though changes in population, as well as in infrastructure, are probable but subject to (unpredictable) near-future socioeconomic development.","""These observations have led me to believe that the global warming is not a 'fake' but the reality,"" Romanovsky said. ""And here, in Alaska, we are dealing already and will be dealing even more in the near future with this reality."" The Paper May Be Misleading

Even though the researchers of this study insist that global warming threat is real, Christopher Burn, a professor of geography and environmental studies at Carleton University, Canada, explains that the paper does not reveal anything that they don't already know.","The coverage and accuracy of pipeline data may vary regionally but we are not aware of any more consistent publicly available global product with comparably high spatial accuracy. As we are not aware of any population projection that would match with the extent of our study area, resolution, and periods analysed, we consider that using current population counts is the safest way to address human exposure to future hazards, even though changes in population, as well as in infrastructure, are probable but subject to (unpredictable) near-future socioeconomic development. Reference 54 estimated that in 2015 the global OSM road network was~83% complete albeit between-country differences were identified.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37967333906&p=1pl&v=1&x=ltio0H7-Rr6r3LuvSX7DEA
10.1038/s41467-018-05870-6,Biology_easy_328,"""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases.""","In the presence of oligomycin, Ago2-deficient hepatocytes showed a higher increase in ECAR compared to controls (Fig.","""Although this is still basic science, we propose that there may be important translational implications for our findings for chronic metabolic disorders like diabetes, fatty liver diseases, and other obesity associated illnesses,"" said Nakamura, senior investigator and a member of the Division of Endocrinology. ""This allows us to explore the potential of finding a novel therapeutic approach that alters energy balance in obesity and modulates the associated diseases."" Novel Science

The scientists caution the research is early stage.","Glucose production was similarly induced between genotypes (Fig. In the presence of oligomycin, Ago2-deficient hepatocytes showed a higher increase in ECAR compared to controls (Fig. Upon the addition of the protonophore carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone (FCCP), Ago2-deficient hepatocytes greatly upregulated oxygen consumption compared to WT controls (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37060860200&p=1pl&v=1&x=8Lal0RIMgLlUZpQnXZ6jPQ
10.1038/s41467-018-05870-6,Biology_easy_329,He pointed out that disruption of these events is already a common feature in obesity and its related illnesses.,Consistent with enhanced capacity for energy production in Ago2-deficiency (Fig.,"But the current paper provides a solid basis for subsequent work. Nakamura said that identifying Ago2's role in the process ""connects the dots"" between how proteins are translated in the liver, how energy is produced and consumed and the activity of AMPK in these processes. He pointed out that disruption of these events is already a common feature in obesity and its related illnesses.","These observations suggest that enhanced protein synthesis in the liver may result in a lowered ATP/ADP ratio and AMPK activation in L-Ago2 KO mice. Consistent with enhanced capacity for energy production in Ago2-deficiency (Fig. 2g) , relative ATP/ADP levels were higher in Ago2-deficient hepatocytes compared to controls, however, the levels were rapidly decreased post-metformin treatment, suggesting a higher energy consumption rate in Ago2-deficiency (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37060860200&p=1pl&v=1&x=8Lal0RIMgLlUZpQnXZ6jPQ
10.1126/science.1256773,Biology_easy_330,"This cell-free system has two huge advantages: It expands the scale of the furrow-building events, making them easier to see, and it gives the researchers an easy way to manipulate the proteins involved.",Live imaging showed partial colocalization of CPC and Kif4A movement ( fig.,"It's hard to see and test such a complex feat in living cells. This cell-free system has two huge advantages: It expands the scale of the furrow-building events, making them easier to see, and it gives the researchers an easy way to manipulate the proteins involved. Quickly removing and returning proteins to see how changes in the molecular players affect cytokinesis is impossible when the cell is whole, but easy when the cellular innards are spread out on a microscope slide.","Kif4A depletion blocked CPC movement, and addback of recombinant Kif4A rescued it (Fig. Live imaging showed partial colocalization of CPC and Kif4A movement ( fig. Thus, the CPC is targeted to the AAIZ and transported to a narrow band by the combined action of Kif20AE and Kif4A.",[1],Biology,train,1.0,news,http://www.science20.com/news_articles/cytokinesis_lite_cellular_division_now_with_no_cells-148202
10.1038/ncomms4999,Biology_easy_331,"Most remarkably, the ringing involves the entire protein, meaning the ringing motion could be responsible for the transfer of energy across proteins.","As the damping g is less than the frequency o 0 , this implies that the vibrational mode involves an underdamped oscillator.","They discovered that this enzyme rings like a bell with a frequency of a few terahertz or a million-million hertz. Most remarkably, the ringing involves the entire protein, meaning the ringing motion could be responsible for the transfer of energy across proteins. The experiments show that the ringing motion lasts for only a picosecond or one millionth of a millionth of a second.","1 ), yielding the parameters o 0 ¼ 1.15 THz and g ¼ 0.52 THz for the broad shoulder and o 0 ¼ 2.80 THz and g ¼ 1.24 THz for the narrow peak. As the damping g is less than the frequency o 0 , this implies that the vibrational mode involves an underdamped oscillator. If the solvated-protein spectrum in the terahertz range were due to multiple localized modes, one would expect an inhomogeneous gaussian distribution of local-mode frequencies-reflecting different local masses and forces-giving rise to a broad overdamped spectrum.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140603092424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.neuron.2014.05.028,Biology_easy_332,The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder).,More studies about this topic would be desirable to further understand the mechanisms of the Tac2/ NkB/Nk3R pathway.,"The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder). ""PTSD is unique among psychiatric disorders in that we know when it starts -- at the time of the trauma. Out of thousands of genes they examined, their ""top gene"" was Tachykinin 2 or Tac2.","To the best of our knowledge, this is the first evidence that a neuronal population specifically highly expressed in the CeM, Tac2 and its product NkB peptide, are required for the modulation of fear memory consolidation affecting neither unconditioned fear nor anxiety-like behavior. More studies about this topic would be desirable to further understand the mechanisms of the Tac2/ NkB/Nk3R pathway. Our findings also suggest that CeA-Tac2 lentiviral overexpression enhances fear memory consolidation but Nk3R antagonism prevents it.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/06/140630124423.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.immuni.2019.05.007,Biology_easy_334,"With this knowledge, vaccine developers will have a better understanding of how, and how often, to reformulate the vaccine over time.","antibodies (7.1 ± 0.5% mean rate of somatic hypermutation) were slightly less mutated than the pre-existing antibodies (8.2 ± 1.1%), this difference did not reach statistical significance.","A human antibody that can target these highly conserved areas will provide broad protection for a prolonged period of time. With this knowledge, vaccine developers will have a better understanding of how, and how often, to reformulate the vaccine over time. The technology, developed by co-author George Georgiou, was used to discover the key antibody in the study and the approach is applicable to a variety of highly variable bacteria and viruses.","Although emergent Table S1 . antibodies (7.1 ± 0.5% mean rate of somatic hypermutation) were slightly less mutated than the pre-existing antibodies (8.2 ± 1.1%), this difference did not reach statistical significance. The anti-GII.4c serological repertoire was predominantly comprised of antibodies using the immunoglobulin heavy variable 3 (IGHV3) family ($80%; Figure 1F ) compared to $30% in naive or mature B cells Mroczek et al., 2014) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39490550792&p=1pl&v=1&x=jZsW-0WrF4cY8V2Qpk9zfA
10.1016/j.cell.2018.04.034,Biology_easy_335,"In contrast, they found that CDK12-mutated mCRPC tumors exhibited a ""distinctive genomic landscape"" that was similar to that identified in a subset of ovarian cancers.","In addition to the singleton outlier RTKs ( Figure S6C ), we found two cases of BRAF fusions (KIAA1549-BRAF and HIPK2-BRAF) generated as a result of a CDK12-FTD ( Figures S6D and S6E ).","""All patients showed biallelic inactivation of CDK12,"" they note, while ""strikingly,"" the CDK12 mutations were mutually exclusive to all of the already known primary genetic drivers (PGDs) analysed, including ETS fusions, SPOP mutations, HRD (homologous recombination-deficiency, ATM mutations and mismatch repair-deficiency (MMRD)."" In contrast, they found that CDK12-mutated mCRPC tumors exhibited a ""distinctive genomic landscape"" that was similar to that identified in a subset of ovarian cancers. ""The prototype CDK12 mutant tumor was baseline diploid and had few arm-level copy-number aberrations except gain of 8q, but notably, hundreds of focal copy-number gains were dispersed across the gnome,"" they state.","All other PGDs had signatures dominated by translocations (49%) and fewer overall duplications (11%) than deletions (18%) or inversions (22%), further supporting the uniqueness of CDK12 mutant PCa. In addition to the singleton outlier RTKs ( Figure S6C ), we found two cases of BRAF fusions (KIAA1549-BRAF and HIPK2-BRAF) generated as a result of a CDK12-FTD ( Figures S6D and S6E ). Surprisingly, we also found a promoter hijacking event leading to outlier expression of ETV1 ( Figure S6F ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1098/rspb.2013.3276,Biology_easy_336,"That's the conclusion of a study published this week in the Proceedings of the Royal Society B, which helps explain how marine communities that depend on isolated methane sources manage to colonize far-flung regions.",mauritanicus via widespread larval dispersal .,"That's the conclusion of a study published this week in the Proceedings of the Royal Society B, which helps explain how marine communities that depend on isolated methane sources manage to colonize far-flung regions. Surface currents, however, move much faster and could potentially carry the larvae across this distance in time. The larvae of two seep-dwellers--a mussel and a small sea snail--were both found in shallow waters.","These genetic findings support a hypothesis of infrequent or historical connectivity of ""B."" mauritanicus via widespread larval dispersal . For ""B.""",[1],Biology,train,1.0,news,http://news.sciencemag.org/environment/2014/05/scienceshot-surface-currents-spread-deep-sea-seep-species
10.1038/s41568-018-0020-9,Biology_easy_337,"I look forward to seeing how the combination of these therapies can affect outcomes in patients for whom this resistance is associated with poor prognoses.""","Therefore, we suggest that HSP90, per se, is not a target in cancer, in the sense that tumours become addicted to HSP90 only when HSP90 becomes integrated into epichaperome networks, potentially explaining the poor performance of HSP90 inhibitors in non-selected patient populations.","By inhibiting epichaperome function and breaking this mechanism, we believe PU-H71 can increase anti-cancer activity of JAK2 inhibitors. I look forward to seeing how the combination of these therapies can affect outcomes in patients for whom this resistance is associated with poor prognoses."" The multicenter Phase 1b study is designed to assess the safety, tolerability, PK and preliminary efficacy of PU-H71 in subjects taking concomitant ruxolitinib.","HSP90 inhibition is lethal only when HSP90 is hyperconnected with the HSP70 machinery and other chaperomes, just as poly(ADP-ribose) polymerase (PARP) inhibition is lethal when breast or ovarian cancer cells harbour BRCA1 or BRCA2 mutations 115 . Therefore, we suggest that HSP90, per se, is not a target in cancer, in the sense that tumours become addicted to HSP90 only when HSP90 becomes integrated into epichaperome networks, potentially explaining the poor performance of HSP90 inhibitors in non-selected patient populations. By analysing 95 cancer cell lines, 40 primary AMLs and 23 primary breast tumours ex vivo and 51 solid tumours and lymphomas in patients, we found that 50-60% express variable epichaperome levels but only ~10% are high expressors, as defined by the amount of HSP90 residing in hyperconnected chaperome networks 35 .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34294149057&p=1pl&v=1&x=pzihluZRVcZJ0XNPGmH0Mw
10.1073/pnas.1511220112,Biology_easy_338,This positioning is consistent with evidence for increasingly sophisticated tool use in Australopithecus.,"The first axis (PC1) is associated with the angle of the scapular spine and glenoid relative to the vertebral border of the blade, which is near perpendicular in MAA proxies and Pongo but has a more cranial orientation in African apes and hylobatids.","The shoulder of Australopithecus afarensis was more like an African ape than a human, and Australopithecus sediba closer to human's than to an ape's. This positioning is consistent with evidence for increasingly sophisticated tool use in Australopithecus. ""The mix of ape and human features observed in Australopithecus afarensis' shoulder support the notion that, while bipedal, the species engaged in tree climbing and wielded stone tools.","2 A-D and Fig. The first axis (PC1) is associated with the angle of the scapular spine and glenoid relative to the vertebral border of the blade, which is near perpendicular in MAA proxies and Pongo but has a more cranial orientation in African apes and hylobatids. More perpendicular spines tend to be longer and the blade wider, accounting for almost all of their covariation (Fig.",[1],Biology,train,1.0,news,http://www.sci-news.com/othersciences/anthropology/science-homo-pan-last-common-ancestor-03220.html
10.1007/s10336-017-1477-0,Biology_easy_339,"The spotted birds certainly don't live in their original location any more, but it's possible they have migrated to another area due to deforestation.",The ND2 sequences obtained from Icterine and White-throated Greenbuls were nearidentical to database sequences obtained by other groups for these species and gave predicted translations yielding full-length ND2 homologous to the mitochondrial protein Fig.,"But despite the thorough genetic analysis and unlikely alternative explanations, we can't yet say that the elusive birds absolutely, definitely don't exist - it looks like once something becomes a species, unspecying it is a tougher ask. ""Formal resolution of the status of the Liberian greenbul will not be possible until either a population of [them] is rediscovered or alternatively shown not to exist,"" the team writes in the study. The spotted birds certainly don't live in their original location any more, but it's possible they have migrated to another area due to deforestation.","'Universal' primers (described in ''Methods'') yielded fulllength ND2 from multiple samples of Icterine Greenbul and White-throated Greenbul, but gave no product from Liberian Greenbul DNA. The ND2 sequences obtained from Icterine and White-throated Greenbuls were nearidentical to database sequences obtained by other groups for these species and gave predicted translations yielding full-length ND2 homologous to the mitochondrial protein Fig. Bootstrap support (100 replicates) for key nodes is indicated.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34855042070&p=1pl&v=1&x=Aj2yuZYjg1DHHMgjyQ7rYg
10.1007/s00244-015-0196-x,Biology_easy_340,"The bats had presumably died of white-nose syndrome, although genetic tests for the fungus were not performed.",Infusion of prostaglandin PGE 2 into the brains of hibernating golden-mantled ground squirrels (Spermophilus lateralis) caused periodic arousals along with increased body temperature .,"The bats had presumably died of white-nose syndrome, although genetic tests for the fungus were not performed. Numerous chemicals were detected in the bat tissues. The PBDE flame retardants were detected in every sample tested.","In Asian chipmunks (Tamias asiaticus), prostaglandin PGD 2 increased in the brain to a maximum in February and declined by April suggesting a correlation between PGD 2 and hibernation . Infusion of prostaglandin PGE 2 into the brains of hibernating golden-mantled ground squirrels (Spermophilus lateralis) caused periodic arousals along with increased body temperature . These studies suggest that prostaglandin levels are related to hibernation in at least these three mammalian species.",[1],Biology,train,1.0,news,http://earthsky.org/earth/bats-also-face-chemical-threats
10.1038/s41467-018-06824-8,Biology_easy_341,The new discovery puts scientists one step closer toward demonstrating a common evolutionary basis for social behavior.,Improved L. albipes genome assembly and annotation.,"The new discovery puts scientists one step closer toward demonstrating a common evolutionary basis for social behavior. ""Finding this gene is a real watershed for the field."" Females in cooler parts of France didn't generally have helpers, whereas those in warmer parts did--there, female bees would lay two sets of eggs, and hatchlings from the first set would tend to the second set of eggs.","Thus, our results are consistent with previous work suggesting that changes in gene regulation play key roles in the evolution of social behavior and that genes known to be associated with social behavior in L. albipes, such as syx1a, may also shape social behavior in other, distantly-related species. Improved L. albipes genome assembly and annotation. The draft L. albipes genome assembly consisted of 41,433 scaffolds with an N50 of~616 kb, a total assembly size of 341 Mb, and an estimated total size of 416 Mb .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37425745606&p=1pl&v=1&x=BF9poLDtNwHfjOufQy7mMA
10.1126/science.1256773,Biology_easy_342,"""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane.","Kif4A depletion blocked CPC movement, and addback of recombinant Kif4A rescued it (Fig.","""We believe our work is a step forward, not only for understanding the assembly of the cleavage furrow but also, more generally, for understanding the biophysics of cytokinesis signaling."" ""To really prove that we reconstituted the cytokinesis signal, we needed to add the bilayer membrane and then see if it could recruit the proteins that would be on the cortex of the cell,"" Field said about the specialized layer beneath the cell membrane. The scientists saw this signal in part because Field chose to include actin in their system, a cellular component that is often discarded because it makes it so difficult to do experiments with the egg extract.","The maximal transport rate was close to that of Kif4A in an isolated aster that was not part of an AAIZ (Fig. Kif4A depletion blocked CPC movement, and addback of recombinant Kif4A rescued it (Fig. Live imaging showed partial colocalization of CPC and Kif4A movement ( fig.",[1],Biology,train,1.0,news,http://www.science20.com/news_articles/cytokinesis_lite_cellular_division_now_with_no_cells-148202
10.1098/rsif.2012.0838,Biology_easy_343,"As the challenge increases, however, the amphibian engages in a sprawling dance.","By reconstructing the angle of the resultant force vectors from the three force components (x, y and z), we were able to plot a graph of force magnitude F against angle a with respect to the substrate ( figure 5 ).","As the challenge increases, however, the amphibian engages in a sprawling dance. The researchers found that this splaying behavior is rooted in the same physical principle that applies to adhesive tape. The easiest way to peel tape away from a surface is by pulling one corner away at the largest possible angle from the sticking surface; pulling the tape at a shallow angle makes it virtually impossible to get unstuck.","However, as the latter study investigated adhesion on rough surfaces, the locusts were splaying out their legs to reduce the approach angle of the claws when interlocking with surface asperities. By reconstructing the angle of the resultant force vectors from the three force components (x, y and z), we were able to plot a graph of force magnitude F against angle a with respect to the substrate ( figure 5 ). The latter is correlated with the surface energy of the newly created surface during crack propagation, but for most tapes the fracture energy is strongly dominated by viscous dissipation.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=frogs-cling-to-and-peel-from-surfaces-just-like-adhesive-tape
10.1111/gcb.13876,Biology_easy_344,"Furthermore, forests and land offer the most cost-effective way to store more carbon right now.","Accounting for these delayed emissions, the net sink for carbon (declining emissions and declining rates of forest re-growth) was greatest immediately after harvests ceased and declined as regrowing forests aged.","In 2017, the world lost 39 million acres (nearly 16 million hectares) of tropical forests -- an area equivalent in size to Bangladesh -- at a near-record rate of 40 football fields every minute for the entire year, according to Global Forest Watch. Furthermore, forests and land offer the most cost-effective way to store more carbon right now. We need to significantly elevate investment in these solutions.","Putting the tropical and temperate zone and boreal forests together, yielded a global gross sink (2006) (2007) (2008) (2009) (2010) (2011) (2012) (2013) (2014) (2015) of 4.4 PgC/year (Table 3) . Accounting for these delayed emissions, the net sink for carbon (declining emissions and declining rates of forest re-growth) was greatest immediately after harvests ceased and declined as regrowing forests aged. The net global carbon sink obtainable if deforestation and harvests were stopped would be À34 PgC by 2100 (15 + 19).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34958843662&p=1pl&v=1&x=ADGn1_xewWPJ_1OZt5xdOA
10.1098/rsos.171474,Biology_easy_345,"Conservatives pushed back hard against the report, which also concluded that veterans coming home from war could be susceptible to recruitment efforts.","Broadly speaking, findings from our study provided evidence that this was not the case.","""When you dehumanize your opponents, whether Democrats, the news, immigrants, people of faith, of different faiths, you're running the risk of someone taking your words and acting upon it."" Conservatives pushed back hard against the report, which also concluded that veterans coming home from war could be susceptible to recruitment efforts. Johnson said that with Trump in office the recruitment, prevalence of the groups and hate crimes have spiked.","Given this popularity, one might argue that a small effect linking violent gaming to aggressive behaviour would have consequences for society as a whole . Broadly speaking, findings from our study provided evidence that this was not the case. Said differently, the results derived from our hypothesis testing did not support the position that violent gaming relates to aggressive behaviour.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39881272230&p=1pl&v=1&x=agjUuQHKttCmyqc0lNUvPA
10.1016/j.cell.2018.04.034,Biology_easy_346,"They identified CDK12 mutations in 25/360 mCRPC patients (6.9%), but in only 6/498 patients with primary prostate cancer.","Indeed, we observed an exceptional response (PSA decline) with anti-PD1 monotherapy in two out of four mCRPC patients in this study ( Figure 7A ).","This is an exciting prospect for patients who have CDK12 alterations and may benefit from immunotherapy."" They identified CDK12 mutations in 25/360 mCRPC patients (6.9%), but in only 6/498 patients with primary prostate cancer. ""All patients showed biallelic inactivation of CDK12,"" they note, while ""strikingly,"" the CDK12 mutations were mutually exclusive to all of the already known primary genetic drivers (PGDs) analysed, including ETS fusions, SPOP mutations, HRD (homologous recombination-deficiency, ATM mutations and mismatch repair-deficiency (MMRD).""","Taken together, our data suggest that CDK12 mutant prostate cancer is intrinsically immunogenic , and CDK12 mutations may identify a subset of patients where immunotherapy would be efficacious. Indeed, we observed an exceptional response (PSA decline) with anti-PD1 monotherapy in two out of four mCRPC patients in this study ( Figure 7A ). Furthermore, identification of CDK12 mutation-associated neoantigens may help in the design of personalized tumor vaccines.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34304544254&p=1pl&v=1&x=4ldt3u_6ItGR2RE2UuBujA
10.1016/j.cell.2013.08.004,Biology_easy_348,The researchers' identification of the role SIK1 plays in the body clock offers a tractable target for drugs that could help travelers adjust faster to changes in time zone and help ameliorate the effects of rotational shift work.,"An entrainment stimulus causes CRTC1 to coactivate CREB, inducing the expression of Per1 and Sik1.","Kevin Flanagan

""Having such a hand-brake on the circadian clock systems makes sense so as to prevent excessive responses to environmental change, and that it is only in our modern 24-hour society, with Thomas Edison's light bulbs, Nikola Tesla's electricity and jet airplanes, that we begin to realize our biological limitations,"" Duffield said. The researchers' identification of the role SIK1 plays in the body clock offers a tractable target for drugs that could help travelers adjust faster to changes in time zone and help ameliorate the effects of rotational shift work. ""Being involved in this project as an undergraduate student and presenting my data at an international conference really crystalized my interest in scientific research as a career,"" Flanagan said.","An entrainment stimulus causes CRTC1 to coactivate CREB, inducing the expression of Per1 and Sik1. SIK1 then inhibits further shifts of the clock by phosphorylation and deactivation of CRTC1. Knockdown of Sik1 within the SCN results in increased behavioral phase shifts and rapid re-entrainment following experimental jet lag.",[1],Biology,train,1.0,news,http://www.healthcanal.com/disorders-conditions/sleep/42436-researchers-identify-new-drug-target-for-treating-jet-lag-and-shift-work-disorders.html
10.1038/s41467-018-06108-1,Biology_easy_349,"Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions.",1 in Akama et al.,"With 450 million base pairs, its genome is somewhat small for a polyploid plant, but still very complex. Advantageous genetic mutations in addition to spare copies

Due to the large amount of genetic information, A. kamchatica is better equipped to adapt to new environmental conditions. ""With these results, we have demonstrated on a molecular-genetic level that genome duplications can positively affect the adaptability of organisms,"" says plant scientist Timothy Paape.","A further step will be to incorporate polymorphism, gene expression, and species distribution data (i.e., landscape genomics) of diploid parents and allopolyploid hybrids to identify the contributions of parental adaptations for broadening climatic regimes and abiotic habitats in polyploids. 1 in Akama et al. Here, the common reads are the reads that aligned equally well to both parental genomes.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/iSCNAuficZY/
10.1098/rsos.171474,Biology_easy_350,"Further, Prince Harry said these games create an addiction that keeps a player hooked to their computer screen for as long as possible.",There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour.,"The authorities received a total of 34 letters, including eight from parents, requesting a ban on the game due to its addictive nature. Further, Prince Harry said these games create an addiction that keeps a player hooked to their computer screen for as long as possible. It's like waiting for the damage to be done and kids turning up on your doorsteps and families being broken down,"" Prince Harry said.","Results did not support this prediction, nor did they support the idea that the relationship between these factors follows a nonlinear parabolic function. There was no evidence for a critical tipping point relating violent game engagement to aggressive behaviour. Sensitivity and exploratory analyses indicated these null effects extended across multiple operationalizations of violent game engagement and when the focus was on another behavioural outcome, namely, prosocial behaviour.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39008420426&p=1pl&v=1&x=Y9M61MqnjfzY0SC9noiwvw
10.1038/s41467-018-04151-6,Biology_easy_351,"""An example of perfect adaptation is our sense of smell,"" she said.","Indeed, it raises the question as to whether all biochemical networks, of any size, with a fundamental need to exhibit robust functionalities, are characterized by modular architectures involving just a small number of topological basis modules.","""My research is giving us a new way to look at unravelling network complexity in nature."" ""An example of perfect adaptation is our sense of smell,"" she said. ""Our sense of smell has exhibited perfect adaptation.","This deep connection between compensation and modularity suggests that a modular design may characterize a wider class of robust networks beyond RPA-capable networks. Indeed, it raises the question as to whether all biochemical networks, of any size, with a fundamental need to exhibit robust functionalities, are characterized by modular architectures involving just a small number of topological basis modules. Several lines of evidence already support the generalization of our network modularization to other bio-signaling contexts.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BUs3tnStd9A/
10.3945/jn.113.188441,Biology_easy_352,"Ahora que sabes que la sopa instantanea puede provocar infartos y derrame cerebral, es mejor que no la consumas tan seguido.","It is interesting to see that there was a simultaneous increase in both healthy metabolic components (HDL cholesterol increase, TG decrease) and some unhealthy metabolic components (abdominal obesity, LDL cholesterol increase) with the MP.","Es decir, comprar la pasta, que venden por separado, y agregar los ingredientes naturales de tu preferencia, asi la sopa no tendra tantos conservadores daninos para tu salud. Ahora que sabes que la sopa instantanea puede provocar infartos y derrame cerebral, es mejor que no la consumas tan seguido. Mas noticias en MSN:

Los 50 peores alimentos para tu corazon (Eat This, Not That!)","The TP, rich in fruit, vegetables, and fish, was inversely associated with abdominal obesity and elevated blood pressure, which is in agreement with previous studies . It is interesting to see that there was a simultaneous increase in both healthy metabolic components (HDL cholesterol increase, TG decrease) and some unhealthy metabolic components (abdominal obesity, LDL cholesterol increase) with the MP. The direct association with increased HDL cholesterol and a decrease in TGs with the MP might be mediated by a reduced intake of carbohydrates , such as polished rice , and an increased intake of fat among those in the highest quintile of the MP; there were similar findings in a Japanese population .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39561372381&p=1pl&v=1&x=lNU4nCAJSUXMnFz01j2kDA
10.1126/sciadv.aau2642,Biology_easy_355,"To lower the risk of extinction, tougher hunting regulations are needed to ensure that the ortolan can make it out of France without ending up on the secret menu of a gourmet restaurant.","An increase in survival representing an additional 30,000 postbreeding live birds (i.e., a reduction of approximately four points of the mortality percentage) would induce a 23% decrease in the 100-year extinction probability, while this decrease would reach 50 to 85% in the most favorable scenarios of reproductive output, mimicking conditions that occurred in northern Europe before the attested large-scale decline of farmland birds .","These northern populations, the study's authors write, are ""directly threatened with extinction and [can]not persist without marked increases in survivorship."" As Parletta notes, the key to these northern ortolans' long-term survival is relatively simple. To lower the risk of extinction, tougher hunting regulations are needed to ensure that the ortolan can make it out of France without ending up on the secret menu of a gourmet restaurant.","S5 ), mild to moderate reductions in mortality probability lead to strong changes in extinction risk and improvements in conservation status. An increase in survival representing an additional 30,000 postbreeding live birds (i.e., a reduction of approximately four points of the mortality percentage) would induce a 23% decrease in the 100-year extinction probability, while this decrease would reach 50 to 85% in the most favorable scenarios of reproductive output, mimicking conditions that occurred in northern Europe before the attested large-scale decline of farmland birds . In these favorable scenarios, a moderate reduction of mortality (five points) is sufficient to improve the Red List conservation status of the population from Endangered to ""Least Concern.""",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39297041118&p=1pl&v=1&x=HPmZkhwNaH9VtCuV7KmVkg
10.1016/j.cell.2016.04.014,Biology_easy_356,The study is available online in Cell.,"When analyses focused on innate versus adaptive lineages, enhancers with augmented H3K27ac levels in Th cells were enriched for motifs bound by BATF/AP1, IRF, NFAT, and EGR ( Figure 3A See also Figure S2 and Tables S1, S2, and S3.","Surprisingly, the regions of DNA that make up these master switches include numerous genetic variants linked to a range of autoimmune diseases, the researchers found. The study is available online in Cell. ""In some cases, individual variations in a person's DNA probably tweak the settings of these switches upward, leading to overactivation of the immune cells and autoimmune disease.""","Many lineage decisions or biological responses are dominated by a single TF or related family. When analyses focused on innate versus adaptive lineages, enhancers with augmented H3K27ac levels in Th cells were enriched for motifs bound by BATF/AP1, IRF, NFAT, and EGR ( Figure 3A See also Figure S2 and Tables S1, S2, and S3. Consistent with this finding, RUNX3 is essential for ILC development in mouse .",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/scientists-discover-master-dimmer-switches-that-control-activity-of-immune-cells/
10.1038/s41467-019-09863-x,Biology_easy_357,Other factors also have the potential to affect the pace of future climate change.,"The corrections φ ω , φ τ , φ p (all non-negative) ensure quasi-independence of the (ω,τ, p) m,s set as a whole from the scenarios or climate models used.","But they're not the only ones that interest scientists. Other factors also have the potential to affect the pace of future climate change. If Greenland or Antarctica were to eventually reach a point of complete collapse, their effects on global sea levels would be catastrophic.","Each combination of a GCM (m) and climate scenario (s), either in SiBCASA or JULES simulations, produces its own set of optimal equilibrium carbon, lag and power parameters (ω,τ, p) m,s that achieves the best emulator fit. The corrections φ ω , φ τ , φ p (all non-negative) ensure quasi-independence of the (ω,τ, p) m,s set as a whole from the scenarios or climate models used. The latter allows us to use these sets of values to construct the corresponding probability distributions for ω,τ, p in PAGE-ICE, which are expected to work throughout the simulated range of temperatures.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39068075992&p=1pl&v=1&x=s9tSrEITwL3rwfEi9cWT-w
10.1098/rsif.2012.0838,Biology_easy_358,"""This experiment shows the maximum adhesive force a frog can take,"" says Thomas Endlein, a biologist at the University of Glasgow, UK, who led the study.","Maintaining a shallow angle of the pulling force vector to the substrate can be achieved by adopting a sprawled posture, placing the adhesive pads as far away from the body as possible.","The easiest way to peel tape away from a surface is by pulling one corner away at the largest possible angle from the sticking surface; pulling the tape at a shallow angle makes it virtually impossible to get unstuck. ""This experiment shows the maximum adhesive force a frog can take,"" says Thomas Endlein, a biologist at the University of Glasgow, UK, who led the study. ""But usually frogs would avoid overhanging surfaces to avoid such difficult sprawling positions.""","by increasing the angle of the leg to the substrate) would facilitate detachment by allowing peeling. Maintaining a shallow angle of the pulling force vector to the substrate can be achieved by adopting a sprawled posture, placing the adhesive pads as far away from the body as possible. These large inward forces help to ensure that the angle of the pulling force vector towards the substrate remains small.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=frogs-cling-to-and-peel-from-surfaces-just-like-adhesive-tape
10.1111/gcb.13276,Biology_easy_359,"""We want this index to be used to predict how corals might react to future bleaching events.","5 -regression continues to decrease for higher taxa below 0.02, but is no longer significant).","""Using very large data sets, we have teased out valuable information that will help researchers identify global trends and learn about individual corals,"" says coauthor Vadim Backman, professor of biomedical engineering. ""We want this index to be used to predict how corals might react to future bleaching events. The index will be available online, so that data on corals can be added as they become available, making the tool even more robust.","Maximal R 2 (0.33) was observed for sites with two taxa, and it monotonically decreased to 0.057 as the number of taxa per site increased to 44 (P < 0.01, Fig. 5 -regression continues to decrease for higher taxa below 0.02, but is no longer significant). Therefore, the effect of extrinsic factors on BRI j is negligibly small, P ext < 6%.",[1],Biology,train,1.0,news,http://www.futurity.org/coral-reefs-climate-change-1138362/
10.1186/s40168-015-0071-z,Biology_easy_360,"""This work significantly advances our efforts to decipher how human milk amazingly orchestrates colonization of the infant gut by helpful bacteria, which then protects and guides intestinal development in the early stages of life.","In non-secretors, the average amount of sialylation was 23.4% ± 5.7%, which is significantly higher than the amounts of sialylation found in secretors, which averaged 18.2% ± 4.8% (p < 0.0001).","The researchers said that understanding the mechanism behind the observed secretor/non-secretor differences may prove critical to compensating for it in situations where the infants are vulnerable, such as by providing carefully chosen pre- or probiotics. ""This work significantly advances our efforts to decipher how human milk amazingly orchestrates colonization of the infant gut by helpful bacteria, which then protects and guides intestinal development in the early stages of life. Understanding this incredible sequence of events will provide examples for how to repair this process where it has been disrupted, such as in premature infants or colicky babies,"" Mills said.","Although the total oligosaccharide abundance and the relative amount of total (including 2′ and 3′) fucosylation were comparable among averaged data from the two phenotypes, the relative abundances of non-fucosylated neutral and sialylated structures differed. In non-secretors, the average amount of sialylation was 23.4% ± 5.7%, which is significantly higher than the amounts of sialylation found in secretors, which averaged 18.2% ± 4.8% (p < 0.0001). Conversely, non-secretor milk had lower relative amounts of non-fucosylated neutral structures than secretor milk, with 21.3% ± 8.8% and 25.4% ± 7.3%, respectively (p = 0.023).",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150409143035.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/pcp/pct167,Biology_easy_361,"""Isolating the genes that determine susceptibility could lead to developing immunities for different varietals and other crop plants and may contribute to general scientific knowledge of the grapevine, which has not been studied to the extent of other plants.""",4) .,"Gassmann says this research will open the door for discussing techniques to breed more resistant grapevines in the future. ""The grapevine could be bred to prevent susceptibility and to keep the character of the wine intact,"" Gassmann said. ""Isolating the genes that determine susceptibility could lead to developing immunities for different varietals and other crop plants and may contribute to general scientific knowledge of the grapevine, which has not been studied to the extent of other plants.""","Average currents in VvNPF3.2-injected oocytes at pH 5.0 were not significantly different from the control when 10 mM amino acids (P > 0.05) or dipeptides (P > 0.1-0.4) were applied (Fig. 4) . However, 10 mM HNO 3 incited currents in these batches of oocytes that were highly significantly different from uninjected control oocytes (P < 0.0001), indicating that VvNPF3.2 selectively transports nitrate.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140430133139.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cell.2013.08.004,Biology_easy_362,"""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and works as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules.""",The same regulatory processes that induce Per1 also induce Sik1.,"We also showed this effect in both peripheral tissues as well as in the clock in the brain. ""It would appear that SIK1 plays a common role in our circadian clocks found throughout our body, and works as a hand-brake on our ability to shift our biorhythms and adjust to new time zones, whether these are real or artificial, such as those produced during shift work schedules."" Kevin Flanagan

""Having such a hand-brake on the circadian clock systems makes sense so as to prevent excessive responses to environmental change, and that it is only in our modern 24-hour society, with Thomas Edison's light bulbs, Nikola Tesla's electricity and jet airplanes, that we begin to realize our biological limitations,"" Duffield said.","An appreciation of the role of CRTC1-SIK1 regulation in these noncircadian pathways very much supports our interpretation of how this signaling pathway functions within the molecular clock. The same regulatory processes that induce Per1 also induce Sik1. In contrast to these kinases, SIK1 does not target the core clock proteins to control their degradation; rather, it attenuates the induction of clock genes in response to entraining stimuli, functioning as a negative-feedback mechanism to deactivate the molecular pathways that are activated following a phase-shifting stimulus.",[1],Biology,train,1.0,news,http://www.healthcanal.com/disorders-conditions/sleep/42436-researchers-identify-new-drug-target-for-treating-jet-lag-and-shift-work-disorders.html
10.1534/genetics.116.197285,Biology_easy_364,"/ no comments





LAWRENCE -- Rest easy, folks.",Lower cleavage rates only slightly decrease establishment probabilities (Fig.,"/ no comments





LAWRENCE -- Rest easy, folks. So natural selection favors individuals lacking modified genes and purges a given genetic alteration within a population within a few generations. ""By doing that they spread through a population much more quickly.""","However, this effect becomes significant only when resistance costs are codominant, not when they are recessive (SI Fig. Lower cleavage rates only slightly decrease establishment probabilities (Fig. This is because for a slower driver it will take longer until resistance alleles from the SGV experience their fitness advantage, increasing their chances of being lost to drift and/or selection in the meantime.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1126/sciadv.aau1291,Biology_easy_366,"The device has only been tested on mice so far, but the results look promising.",As shown in Fig.,"The device has only been tested on mice so far, but the results look promising. It regulates brain activity much like a pacemaker regulates heart rhythm by sending its own signals regardless of what the rest of the brain might be doing. The implant is not without risks, since it requires invasive, risky brain surgery.","This illustrates the importance of choosing the appropriate drug of interest and effectively rules out the small current stimulus (average, <35 nA) associated with the FIP operation as the primary therapeutic mechanism. As shown in Fig. 4 , in the absence of additional GABA delivery, the second 4AP injection induced a series of intense SLEs.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34950349292&p=1pl&v=1&x=ffMz4n5n4XLtDMruPZnsFg
10.1016/j.cell.2016.09.056,Biology_easy_367,"The wager paid off, and the researchers got their first full look at a tetraspanin--including some unique and unexpected features.",Our molecular dynamics simulations suggest that CD81 may exist in both closed and open conformations and that the equilibrium between closed and open conformations may be shifted toward the closed state when cholesterol is bound.,"Others shrugged, figuring the transmembrane portion wasn't important but merely served as an anchor for the outer segment. The wager paid off, and the researchers got their first full look at a tetraspanin--including some unique and unexpected features. ""Brandon's perseverance and biochemical skills and Andrew's determination and deep knowledge of membrane protein structural biology made it possible,"" said Blacklow.","Our results reveal that CD81 binds cholesterol and that E219 is an important residue in the binding pocket, offering a potential mechanism for how tetraspanins might detect cholesterol or other membrane lipids (whereas CD81 and tspan10 both possess a polar residue in this position, most other tetraspanins have a polar residue one helical turn earlier, with other cholesterol-interacting residues highly conserved throughout evolution). Our molecular dynamics simulations suggest that CD81 may exist in both closed and open conformations and that the equilibrium between closed and open conformations may be shifted toward the closed state when cholesterol is bound. Modulation of tetraspanin conformation in response to differences in cholesterol concentration could explain how tetraspanins regulate the subcellular localization of their partner proteins D117   K116   D117   K201   D196   TM3  TM3  TM4  TM4   EC2  EC2   EC2   EC2   TM1   TM2   TM3   TM4   F58 F126 6 6 6 6 6 6 6 6 6 6 6 6 6 E EC2",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Ay74vlkGcfw/
10.1186/s40168-015-0071-z,Biology_easy_370,And they were right.,"Conversely, non-secretor milk had lower relative amounts of non-fucosylated neutral structures than secretor milk, with 21.3% ± 8.8% and 25.4% ± 7.3%, respectively (p = 0.023).","So those women make much less of the special sugar. And they were right. The study only included 44 women, but it was still telling.","In non-secretors, the average amount of sialylation was 23.4% ± 5.7%, which is significantly higher than the amounts of sialylation found in secretors, which averaged 18.2% ± 4.8% (p < 0.0001). Conversely, non-secretor milk had lower relative amounts of non-fucosylated neutral structures than secretor milk, with 21.3% ± 8.8% and 25.4% ± 7.3%, respectively (p = 0.023). No obvious differences between secretor and non-secretor groups were found (Tables 2 and 3 ).",[1],Biology,train,1.0,news,http://medcitynews.com/2015/04/one-gene-mother-can-affect-bacteria-babys-gut/
10.1038/s41467-018-05229-x,Biology_easy_371,"This is due to the system's extremely high optical nonlinearity, which occurs when Wannier-Stark localization sets in.",In Fig.,"Under the extreme conditions of the experiment, a bright red glow can be seen to emanate from the gallium arsenide crystal used as a semiconductor. This is due to the system's extremely high optical nonlinearity, which occurs when Wannier-Stark localization sets in. The system remains stable as long as the rubber band is as strong as the repulsion is.","Under these conditions, a clear temporal modulation of differential absorption manifests itself in horizontally oriented differential transmission patterns with twice the periodicity of the biasing transients that are visible in Fig. In Fig. For E < 100 kV/cm, Franz-Keldysh signatures similar to the ones found experimentally in Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34670950732&p=1pl&v=1&x=x3oAuC5eU9X8uvPYQct7_A
10.1038/s41467-019-09863-x,Biology_easy_372,"Sto metaxu, khores opos e Norbegia, o Kanadas kai e Souedia einai 25-34% pio plousies ap' o,ti tha etan khoris tis pio megales pagkosmies thermokrasies.","The SAF emulator models the global SAF as a function of the GMST (Methods), reproducing the nearly monotonic decline driven largely by the Arctic sea ice and land snow components.","Eno e omada tou Yumashev kataskeuase tis mellontikes sunthekes tes klimatikes allages, mia melete pou demosieuteke prosphata sto Proceedings of the National Academy of Sciences ektima ten pagkosmia oikonomike zemia pou ekhei ede proklethei. Sto metaxu, khores opos e Norbegia, o Kanadas kai e Souedia einai 25-34% pio plousies ap' o,ti tha etan khoris tis pio megales pagkosmies thermokrasies. E omada upologise auta ta noumera exetazontas makrokhronia thermokrasia kai metreseis AEP se 165 khores, gia na doun an uperkhe skhese anamesa sten oikonomike anaptuxe kai tis diakumanseis tes thermokrasias.","In contrast, the SAF for the rest of the world stays nearly constant until high GMST anomalies. The SAF emulator models the global SAF as a function of the GMST (Methods), reproducing the nearly monotonic decline driven largely by the Arctic sea ice and land snow components. 2 ), which is implicitly included in the 2 × CO 2 ECS parameter (Methods), the SAF emulator accounts for the difference between the nonlinear SAF and its constant legacy value.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39093010673&p=1pl&v=1&x=sZM4NVw7ruP2hKMrRk-2DA
10.1098/rsos.180695,Biology_easy_377,"""We'll become less capable of coping with climate change.""","Based purely on its indoor temperature and humidity, you would be unlikely to discern whether a house from our dataset was in Wyoming or Mississippi.","We could also be adapting to the cozy indoor climates where we spend most of our time, speculates Gilligan. And while the inside of a house may be similar to an African savannah, the house will probably stay more constant than any real outdoor climate. ""We'll become less capable of coping with climate change.""","They do so to such an extent that indoor climate is no longer well correlated to outdoor climate (table 1) . Based purely on its indoor temperature and humidity, you would be unlikely to discern whether a house from our dataset was in Wyoming or Mississippi. Of the two climatic variables, we considered, indoor humidity was more strongly correlated with outdoor conditions than was the case for temperature, but this correlation was weak.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38798635240&p=1pl&v=1&x=dKEYUvmyKXnUNRgeE2st1A
10.1038/s41590-018-0068-4,Biology_easy_378,These results suggest that TLR8 acts as a key switch for protective immune responses.,(Fig.,"Moreover, the scientists also found that patients carrying an activating TLR8 gene variant responded better to a live vaccine against tuberculosis, which resulted in improved protection against disease. These results suggest that TLR8 acts as a key switch for protective immune responses. ""These results may enable us to develop new vaccines that will combine the safety of modern subunit vaccines with the high efficacy of live vaccines.""",Recognition of bacterial viability is conserved in porcine APCs. (Fig. Secretion of IL-6 was induced similarly by live and dead EC and ST (Fig.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33723683656&p=1pl&v=1&x=R9OQAdHcxos4adubuX4cGg
10.1038/s41467-019-09863-x,Biology_easy_379,"<<Ta euremata mas sterizoun ten anagke gia pio energa metra periorismou gia na parameinei e auxese tes pagkosmias thermokrasias kato apo 2 bathmous Kelsiou>>, delose o Yumashev.",Such assessments could provide a more complete understanding of the socio-economic risks from climate change that in turn can help guide policymakers towards prudent decisions on emissions reduction targets.,"VICE Video: Oi Ellenes pou Pisteuoun oti e Ge Einai Epipede

Parakoloutheste ola ta binteo tou VICE, meso tes neas selidas VICE Video Greece sto Facebook. <<Ta euremata mas sterizoun ten anagke gia pio energa metra periorismou gia na parameinei e auxese tes pagkosmias thermokrasias kato apo 2 bathmous Kelsiou>>, delose o Yumashev. Tetoia metra perilambanoun ten ektetamene epharmoge ananeosimon energeion opos e eliake energeia.","The methodology introduced in this paper could be used to quantitatively assess the economic and climate policy implications of the other tipping elements in the Earth's climate system, including the Greenland and West Antarctic ice sheets, Amazon rainforest, boreal forest, Sahel and ENSO 13 . Such assessments could provide a more complete understanding of the socio-economic risks from climate change that in turn can help guide policymakers towards prudent decisions on emissions reduction targets. The imaginary Zero Emissions scenario in which all global emissions stop in the base year 2020 characterises the effect of the historic emissions on the PCF and SAF.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39093010673&p=1pl&v=1&x=sZM4NVw7ruP2hKMrRk-2DA
10.1016/j.neuron.2014.05.028,Biology_easy_382,The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder).,"Using double fluorescent in situ hybridization (FISH), we show that Tac2 gene expression is mostly not colocalized with PKCd or Enk and is expressed primarily within the CeM (Figures 2A-2F ).","Potential drug target for PTSD prevention

The dark smudge on the left side shows that the gene Tac2 is robustly activated after fear learning in the central amygdala. The finding may accelerate the development of treatments for preventing PTSD (post-traumatic stress disorder). ""PTSD is unique among psychiatric disorders in that we know when it starts - at the time of the trauma.","Of note, Enk mRNA levels are increased after FC in the CeL (Petrovich et al., 2000) . Using double fluorescent in situ hybridization (FISH), we show that Tac2 gene expression is mostly not colocalized with PKCd or Enk and is expressed primarily within the CeM (Figures 2A-2F ). Thus, given the lack of colocalization and regional and functional specificity of these cell populations, we have uncovered a subdivision-specific cell population that may be involved in the consolidation of fear memory.",[1],Biology,train,1.0,news,http://www.healthcanal.com/mental-health-behavior/52580-potential-drug-target-for-ptsd-prevention.html
10.1038/s41467-018-08038-4,Biology_easy_383,"""This could fundamentally improve our understanding of how these small biological systems function.","All-in-all, these results show that, at this acoustic frequency, the noise equivalent pressure of the sensor is within 9% of the noise floor introduced by thermal collisions of gas molecules with the sensing element.","""We'll soon have the ability to listen to the sound emitted by living bacteria and cells,"" she said. ""This could fundamentally improve our understanding of how these small biological systems function. ""A deeper understanding of these biological systems may lead to new treatments, so we're looking forward to seeing what future applications emerge.""","The gas damping noise power therefore dominates by a factor of γ gas / γ~7.4. All-in-all, these results show that, at this acoustic frequency, the noise equivalent pressure of the sensor is within 9% of the noise floor introduced by thermal collisions of gas molecules with the sensing element. This gas damping noise floor is fundamental, in that it cannot be eliminated without removing the gas through which the acoustic wave itself propagates.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38265192014&p=1pl&v=1&x=jM9LqTh2dU9LfWHNQwm_FQ
10.1534/genetics.116.197285,Biology_easy_386,"The KU researcher said by tying the mutation for shorter lifespan, or resistance to dengue fever in mosquitoes, for example, to one of these selfish genetic elements that can drive through populations, scientists found a way to overcome fitness cost.","We also limited our study to resistance at the target site, even though trans resistance might be common.","""By doing that they spread through a population much more quickly."" The KU researcher said by tying the mutation for shorter lifespan, or resistance to dengue fever in mosquitoes, for example, to one of these selfish genetic elements that can drive through populations, scientists found a way to overcome fitness cost. ""It's compensated for by the Mendelian cheating going on, so you can spread it through a population.","Furthermore, resistance alleles may be created if homology-directed repair inserts the driver construct, but introduces errors that prevent it from driving. We also limited our study to resistance at the target site, even though trans resistance might be common. CGD hosts may harbor natural variation for Cas9 expression levels or may produce peptides or RNA that silences the CRISPR machinery 30 .",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/research-shows-nature-can-beat-back-scientific-tinkering-with-genes-of-entire-species/
10.1086/693564,Biology_easy_387,"The Virginia-based nonprofit group claimed the auction raised $182,500 for its conservation programs.",We make the simplifying assumption that mites on vertebrates are relatively well studied (given that thousands of species have already been described).,"The Virginia-based nonprofit group claimed the auction raised $182,500 for its conservation programs. The most valuable animal turned out to be a wormlike amphibian from Panama, which drew a winning bid of $25,000 from a British sustainable building materials company called EnviroBuild. With more than 27,000 species at risk of extinction, auctioning off naming rights seems like a fairly harmless way to increase public awareness and raise much-needed funding for conservation efforts.","1998; ; specifically these four studies respectively estimated ratios of beetle species to mite species of 4∶7, 38∶36, 51∶36, and 30∶33 for a mean ratio across studies of 1.13 or a combined ratio, based on species and not separate studies, of 123∶112 or 0.91). We make the simplifying assumption that mites on vertebrates are relatively well studied (given that thousands of species have already been described). Moreover, even if each bird and mammal species had an average of 30 unique mite species (almost certainly an overestimate; Walter and Proctor 2013), the impact on overall mite diversity would be limited relative to estimated mite diversity overall (e.g., 10,000 bird + 5000 mammal species × 30 mites per species = 450,000 mite species).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38981580573&p=1pl&v=1&x=Y8hj7JQLdrpGIg7lpFM9kg
10.1111/1365-2656.12871,Biology_easy_390,"""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus.",We believe that future research avenues should include investigating disease transmission dynamics at finer temporal scales to test the importance of heterogeneity in modes of RHDV transmissions and doses of infection on the mortality rates of rabbits susceptible to RHDV.,"It is no longer a case of which disease is a better control agent, because their effectiveness is intrinsically linked."" ""The effect of RHDV disease virus on rabbits is enhanced by previous infection with MYXV virus. Survival rates were lowest for rabbits which survived MYXV infection and then were exposed to RHDV disease,"" says Dr Fordham from the University's Environment Institute.","This argument could partly explain recent on-ground observations of increased survival (i.e., less infection-induced mortality) and abundance of South Australian rabbit populations and in silico evidence of rabbits escaping infection in some years . We believe that future research avenues should include investigating disease transmission dynamics at finer temporal scales to test the importance of heterogeneity in modes of RHDV transmissions and doses of infection on the mortality rates of rabbits susceptible to RHDV. Our analysis was restricted by practical limits to relatively long time intervals (ca.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34506942217&p=1pl&v=1&x=OCP5j07SbNKK_Tx7JPH1Dw
10.1038/s41467-018-04906-1,Biology_easy_391,"Not only that, the technology could also potentially allow smartphone manufacturers to extend the fingerprint sensor's coverage on a larger portion of a smartphone display.","Both R s and T decrease as their area fraction increases, as shown in Supplementary Fig.","""Furthermore, this fingerprint sensor array can be integrated with all transparent forms of tactile pressure sensors and skin temperature sensors, to enable the detection of a finger pressing on the display."" Not only that, the technology could also potentially allow smartphone manufacturers to extend the fingerprint sensor's coverage on a larger portion of a smartphone display. In theory, this means that user's won't have to worry about where they have to place their finger when they try to unlock their phones.","The area fraction of the AgNF and AgNW networks, which can be controlled by the electrospinning duration, determines R s and T of the transparent AgNF-AgNW hybrid electrode. Both R s and T decrease as their area fraction increases, as shown in Supplementary Fig. Figure 2c presents R s of the resulting AgNF-AgNW hybrid network as a function of its T in the visible light range (wavelength: 550 nm).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1098/rsos.171474,Biology_easy_392,The draft is currently awaiting revision by parliament's speaker.,"Finally, in this study, we draw general inferences about gaming effects in a general way across the population as a whole.","""The committee is concerned about the obsession over these electronic games that ignite violence among children and youth. The draft is currently awaiting revision by parliament's speaker. In one incident in November, a youngster reportedly killed his friend with a shotgun in Erbil province while recreating a PUBG scene.","To this end, field or natural experiments using multi-wave random-intercepts cross-lagged panel modelling should follow the present work to provide an expanded test of the effects of violent gaming on human behaviour. Finally, in this study, we draw general inferences about gaming effects in a general way across the population as a whole. It might be the case that specific cohorts of people sharing background factors associated with technology use such as carer educational attainment or material deprivations are more or less likely to be influenced by their experiences with virtual environments .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39008420426&p=1pl&v=1&x=Y9M61MqnjfzY0SC9noiwvw
10.1016/j.mito.2018.08.001,Biology_easy_393,"A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first.","Disruption of cellular communication, and the associated increase in cell-autonomous and paracrine signaling by metabokines during the CDR is tightly associated with either a disruption in normal parasympathetic tone from the VVC, or end-organ resistance to cholinergic signals.","The molecular features of this process are universal,"" said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego. A concussion sustained before an earlier concussion has completely resolved typically results in more severe symptoms and prolonged recovery, even if the second impact is less than the first. When the abnormal ATP signaling was silenced, the treated boys in the trial displayed dramatically improved communication and social behaviors.","When the CDR is chronically activated, the coordination between the two limbs of the vagus is disrupted. Disruption of cellular communication, and the associated increase in cell-autonomous and paracrine signaling by metabokines during the CDR is tightly associated with either a disruption in normal parasympathetic tone from the VVC, or end-organ resistance to cholinergic signals. Substages of the CDR occur during the transition between a fully active ventral vagus complex in health, its rapid inhibition by CDR1, and its gradual return in CDR3.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37036494336&p=1pl&v=1&x=fSLbjdg9pAN1rFXsEu2RGA
10.1016/j.cell.2018.06.045,Biology_easy_394,"Only small amounts of blood, just a few drops from each baby, are needed to analyse all the white blood cells and hundreds of proteins circulating in the blood.","These data reveal drastic changes across immune components after birth, following a stereotypic pattern shared by all children, but not predictable from cord blood measurements.","""We saw drastic changes in the babies' immune system between each sampling, which shows that it is highly dynamic early in life."" Only small amounts of blood, just a few drops from each baby, are needed to analyse all the white blood cells and hundreds of proteins circulating in the blood. The researchers were also able to show that the babies who had abnormal development of the gut flora during the first weeks also demonstrated a disorder of the immune system.","Human systems immunology analyses have now revealed not only large interindividual variation in immune cells and in protein composition but also a stability of phenotypes within individuals over the course of weeks to months , and even a few years (Shen-Orr et al., 2016) . These data reveal drastic changes across immune components after birth, following a stereotypic pattern shared by all children, but not predictable from cord blood measurements. The cell and protein changes occurring imply interactions with microbes as important, and, in a subset of children with gut bacterial dysbiosis, stereotypic immune system development is hampered.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34901466233&p=1pl&v=1&x=3s65PefAzHVGUtcPhREU_Q
10.1038/s41589-018-0155-8,Biology_easy_395,"""This is a good example of how the study of a rare genetic disease can reveal a pathway that plays a key role in human biology,"" says study co-senior author Benjamin Cravatt, professor and chair of the Department of Chemical Physiology at Scripps Research.",4a and Supplementary Fig.,"It also indicates that ABHD12 may be a useful target for drugs that boost the immune system -- for example against cancers and viruses that normally persist by shutting down people's immune defenses. ""This is a good example of how the study of a rare genetic disease can reveal a pathway that plays a key role in human biology,"" says study co-senior author Benjamin Cravatt, professor and chair of the Department of Chemical Physiology at Scripps Research. The team found that in adult mice, reducing ABHD12 activity with the inhibitor led to a rise in lyso-PS in immune cells called macrophages, as well as in brain tissue.","Maximal lyso-PS and 20:4 PS elevations were observed at 30 mg/kg of DO264, which matched the dose at which full ABHD12 inhibition was observed ( Fig. 4a and Supplementary Fig. Time-course studies revealed that the lyso-PS changes caused by DO264 were detectable by 4 h and were maximal at 24 h post dosing ( Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37814264274&p=1pl&v=1&x=fV_-TrzPs9X1ZtNnkmq4RQ
10.1373/clinchem.2012.187617,Biology_easy_396,"One of his eyeballs swelled slightly and his telomeres, special caps on the ends of his DNA strands, also experienced long-term shortening upon return to Earth -- both are phenomena seen generally among space station astronauts.","Manipulation of the gut microbiota may be an important therapeutic strategy to regulate energy balance in individuals who are obese, diabetic, or have a diagnosis of metabolic syndrome.","His cognitive speed and accuracy declined, persisting through six months after he landed. One of his eyeballs swelled slightly and his telomeres, special caps on the ends of his DNA strands, also experienced long-term shortening upon return to Earth -- both are phenomena seen generally among space station astronauts. Overall, NASA views this study as good news so far for their plans of crewed missions to Mars.","These data support a pivotal role for the gut microbiome in the pathogenesis of obesity and obesity-related disorders. Manipulation of the gut microbiota may be an important therapeutic strategy to regulate energy balance in individuals who are obese, diabetic, or have a diagnosis of metabolic syndrome. analyzed bacterial 16S rRNA gene sequences from the cecal microbiota and reported that ob/ob mice had 50% fewer Bacteroidetes and correspondingly more Firmicutes than their lean littermates and this difference was unrelated to differences in food consumption.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38972928248&p=1pl&v=1&x=ysfCh3UQ1PqOUUs0UQwPzg
10.1038/nrg2703,Biology_easy_397,"""It's remarkable that something so random actually ends up working,"" Jones said.",Lampreys have two VLR genes: VLRA and VLRB .,"It just takes one grain to fertilize the female part of a plant, so casting fate to the wind isn't a bad strategy. ""It's remarkable that something so random actually ends up working,"" Jones said. Animals in that environment evolved with pollen all around them.","The majority of variable residues in the VLR are located on the concave surface, which suggests that this surface is involved in antigen binding . Lampreys have two VLR genes: VLRA and VLRB . Both seem to be expressed exclusively in lymphoid cells, and they usually exhibit allelic exclusion.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34307692391&p=1pl&v=1&x=mm-osFSBw9YRNm7JQuxdew
10.1038/s41467-018-04906-1,Biology_easy_398,The researchers believe that their fingerprint sensor is more secure and it even satisfies FBI standards.,"In addition, R s of the AgNF-AgNW hybrid electrode decreased further to~0.012 ± 0.0008 Ω/sq with T of 24.11% by increasing their densities.","In theory, this means that user's won't have to worry about where they have to place their finger when they try to unlock their phones. The researchers believe that their fingerprint sensor is more secure and it even satisfies FBI standards. The researchers also claim that the new technology improves current scanning methods by up to 17 percent.","This optoelectronic property was superior to that of other transparent conducting materials, such as ITO (R s >~50 Ω/sq), networks of metal nanowires (R s >~20 Ω/sq), or chemical vapor depositionsynthesized graphene (R s >~100 Ω/sq for undoped cases). In addition, R s of the AgNF-AgNW hybrid electrode decreased further to~0.012 ± 0.0008 Ω/sq with T of 24.11% by increasing their densities. AgNF-AgNW hybrid networks can be photolithographically patterned using wet etching without any significant increase in the resistance, compared to the cases where only singular components of AgNWs or AgNFs were used with no hybrid structure (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34467889819&p=1pl&v=1&x=bwlU4e1aRXgMmGqDDaSdMA
10.1002/emmm.201302567,Biology_easy_399,Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood.,"Compared with neonatal administration, this procedure elicited late-onset motor phenotypes.","People who have 2-3 copies (Type II SMA) make more protein and survive longer, but can never walk. Type IV SMA patients have 4 or more copies of the SMN2 gene and don't experience effects of the disease until adulthood. The flaw in the protein's production is understood.","Here, we have shown that a single injection of an exonskipping ASO into the cerebral ventricles phenocopies adultonset SMA. Compared with neonatal administration, this procedure elicited late-onset motor phenotypes. In adult mice with Smn-null background, the SMN levels required for normal CNS function correspond to an SMN2 copy number less than two, suggesting that only moderate SMN levels are necessary for therapy in adult-onset SMA.",[1],Biology,train,1.0,news,http://www.healthcanal.com/medical-breakthroughs/42722-first-animal-model-of-adult-onset-sma-sheds-light-on-disease-progression-and-treatment.html
10.1038/s41467-018-05664-w,Biology_easy_400,The group also demonstrated a two-qubit holonomic gate to show universality by manipulating the electron-nucleus entanglement.,We also demonstrate a two-qubit holonomic gate to show universality by manipulating the electron−nucleus entanglement.,"This method facilitated fast and precise geometric gates at a temperature below 10 K, and the gate fidelity was limited by radiative relaxation,"" says the corresponding author Hideo Kosaka, Professor, Yokohama National University. The group also demonstrated a two-qubit holonomic gate to show universality by manipulating the electron-nucleus entanglement. The scheme renders a purely holonomic gate without requiring an energy gap, which would have induced dynamic phase interference to degrade the gate fidelity, and thus enables precise and fast control over long-lived quantum memories, for realizing quantum repeaters interfacing between universal quantum computers and secure communication networks.","We also demonstrate a two-qubit holonomic gate to show universality by manipulating the electron−nucleus entanglement. The universal holonomic gates enable fast and fault-tolerant manipulation for realising quantum repeaters interfacing between universal quantum computers and secure communication networks. However, these experiments required microwaves 20 or light waves 24 in two frequencies differing by the energy gap for manipulating the nondegenerate subspace, leading to the degradation of gate fidelity due to the unwanted interference of the dynamic phase.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34803186941&p=1pl&v=1&x=lE49IeUHg9oYX2lVpw-cqg
10.1038/s41467-018-02954-1,Biology_easy_401,"""Embracing such new adaptation pathways will present considerable national scale challenges to planning, development goals and land tenure systems,"" they said.","Embracing such new adaptation pathways will present considerable national-scale challenges to planning, development goals and land tenure systems.","The study's authors said island nations needed to find creative solutions to adapt to climate change that take into account their homeland's evolving geography. ""Embracing such new adaptation pathways will present considerable national scale challenges to planning, development goals and land tenure systems,"" they said. ""However, as the data on island change shows there is time (decades) to confront these challenges.""","Not least at issue here is the requirement for significant and continued economic investment, including the development of opportunities for appropriate economic growth and sustained adaptive capacity. Embracing such new adaptation pathways will present considerable national-scale challenges to planning, development goals and land tenure systems. However, as the data on island change show there is time (decades) to confront these challenges, which could engender more thoughtful support from international agencies.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=33251661889&p=1pl&v=1&x=lr0IkZYklRRn8uy2Q7kKrA
10.1073/pnas.1219361110,Biology_easy_402,"Female mate choice could have driven the evolution of larger penises in humans.""",Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans.,"And at a certain point in either direction, as witnessed by the 31-year-old virgin, human genitalia can get out of hand. Female mate choice could have driven the evolution of larger penises in humans."" ""If you picture a bell curve [of penis size], you've got the 95 percent that are normal, and then you have 2.5 percent that are way too big and 2.5 percent that are way too small,"" Brown explains.","Surprisingly, larger penis size and greater height had almost equivalent positive effects on male attractiveness. Our results support the hypothesis that female mate choice could have driven the evolution of larger penises in humans. More broadly, our results show that precopulatory sexual selection can play a role in the evolution of genital traits.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34102449597&p=1pl&v=1&x=jQNreBADNzC6cPm_zJjKMA
10.1083/jcb.201710132,Biology_easy_403,"""Overall, we think that increased expression of Munc13-4, combined with elevated calcium levels, drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention,"" Martin says.","We propose that the increased expression of Munc13-4 in cancer cells after epithelial-to-mesenchymal transition combined with increased Ca 2+ uptake drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention.","This helps the cancer cells disperse around the body to form secondary metastatic tumors. When Martin and colleagues depleted Munc13-4, they reduced the release of MT1-MMP-containing exosomes from breast cancer cells and inhibited the cells' ability to degrade the extracellular matrix. ""Overall, we think that increased expression of Munc13-4, combined with elevated calcium levels, drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention,"" Martin says.","This Ca 2+ -, Munc13-4-, and Rab11dependent pathway generated secretion-competent MVBs for basal and Ca 2+ -stimulated CD63 + exosome release. We propose that the increased expression of Munc13-4 in cancer cells after epithelial-to-mesenchymal transition combined with increased Ca 2+ uptake drives enhanced exosome release by highly aggressive cancer cells, and that Munc13-4 is a potential target for therapeutic intervention. The acute (30-min) elevation of intracellular Ca 2+ with ionomycin treatment enhanced CD63 + , CD9 + , and ALIX + exosome release by approximately fivefold in control MDA-MB-231 cells (Fig.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34362583588&p=1pl&v=1&x=F6YnUwN2LwoCB0GEaW5i4g
10.1038/s41467-018-04632-8,Biology_easy_404,"""Our network-centric approach,"" the researchers wrote, ""has exciting potential applicability on diverse intra- and inter-species interactomes, including human protein-protein interaction networks, in efforts to unravel host-pathogen contact points, while fostering the design of targeted therapeutic strategies.""","Our network-centric approach has exciting potential applicability on diverse intra-and inter-species interactomes including human PPI networks in efforts to unravel host-pathogen contact points, while fostering the design of targeted therapeutic strategies.","When the internal portions of the cell-surface proteins were tested for interactions with effector proteins from the bacterial pathogen Pseudomonas syringae, the researchers were able to identify seven previously unknown effector targets, a discovery rate of 40 percent. The researchers made mutants of the seven effector targets and found that all of the newly identified targets showed changes in pathogen growth on Arabidopsis plant leaves when mutated. ""Our network-centric approach,"" the researchers wrote, ""has exciting potential applicability on diverse intra- and inter-species interactomes, including human protein-protein interaction networks, in efforts to unravel host-pathogen contact points, while fostering the design of targeted therapeutic strategies.""","The detailed curation of our Arabidopsis phenotypic dataset can be useful to the scientific community for additional genome-to-phenome studies. Our network-centric approach has exciting potential applicability on diverse intra-and inter-species interactomes including human PPI networks in efforts to unravel host-pathogen contact points, while fostering the design of targeted therapeutic strategies. Therefore, R=(r ij )=[D−A+J]−1.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34300512407&p=1pl&v=1&x=WKaXG41IVkVX1fiEnqIJcA
10.1038/ng.3611,Biology_easy_405,"""This is despite climate change and anthropogenic transformations of local flora and fauna, including changes in agricultural practices, which might have favored the introduction of landraces from other regions that were better adapted to the changing agricultural environment.""","This is despite climate change and anthropogenic transformations of local flora and fauna, including changes in agricultural practices , which might have favored the introduction of landraces from other regions that were better adapted to the changing agricultural environment.","""Despite hybridization events between wild and domesticated barleys over the last six millennia, the overall picture is that the genomes of extant Levantine landraces have remained remarkably similar to how they were 6,000 years ago,"" the scientists explained. ""This is despite climate change and anthropogenic transformations of local flora and fauna, including changes in agricultural practices, which might have favored the introduction of landraces from other regions that were better adapted to the changing agricultural environment."" ""Although we found no indications of major lineage turnovers in the barley crop from the Southern Levant, the eventful history of this region makes it likely that the farmers who grew cereals there several millennia ago are not the ancestors of those who tend the present-day landraces.","Despite hybridization events between wild and domesticated barleys over the last six millennia, the overall picture is that the genomes of extant Levantine landraces have remained remarkably similar to how they were 6,000 years ago. This is despite climate change and anthropogenic transformations of local flora and fauna, including changes in agricultural practices , which might have favored the introduction of landraces from other regions that were better adapted to the changing agricultural environment. Although we found no indications of major lineage turnovers in the barley crop from the Southern Levant (as have, for example, been observed in Near Eastern pig populations 3 ), the eventful history of this region makes it likely that the farmers who grew cereals there several millennia ago are not the ancestors of those who tend the present-day landraces .",[5],Biology,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/bVR0QLo50zk/genome-ancient-barley-04034.html
10.1093/molbev/msw148,Biology_easy_406,"""These changes are particularly common among dipsadine and colubrine 'higher' snakes.""","These changes are particularly common among dipsadine and colubrine ""higher"" snakes.","However, the team also discovered that the genes have undergone a great amount of evolution, including many changes to the wavelengths of light that the pigments are sensitive to, in order to suit the diversity of lifestyles that snakes have evolved. ""These changes are particularly common among dipsadine and colubrine 'higher' snakes."" Most snakes examined in the new study are sensitive to UV light, which likely allows them to see well in low light conditions.","These changes are particularly common among dipsadine and colubrine ""higher"" snakes. All three opsin genes are inferred to be under purifying selection, though dN/dS varies with respect to some lineages, ecologies, and retinal anatomy. Positive selection was inferred at multiple sites in all three opsins, these being concentrated in transmembrane domains and thus likely to have a substantial effect on spectral tuning and other aspects of opsin function.",[5],Biology,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/8T9Gokbc0GQ/snake-vision-04206.html
10.1016/j.bpj.2013.12.017,Biology_easy_407,"Activation of the immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within about one week; however, bacteria at the edge of the rash continue to spread outward, further activating the immune response away from the edge.","Activation of the innate immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within~1 week.","The model reveals that in these cases, the rash begins as a small and uniform rash. Activation of the immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within about one week; however, bacteria at the edge of the rash continue to spread outward, further activating the immune response away from the edge. Therefore, the rash grows, but the center becomes less inflamed.","2 g shows a radial slice through a simulated central erythema and shows how the spirochete and macrophage populations change as the rash progresses. Activation of the innate immune response is strongest at the center of the rash and clears most, but not all, of the bacteria from the center within~1 week. Therefore, the rash grows, but the center becomes less inflamed.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/02/140204123611.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-06358-z,Biology_easy_408,"The higher the warming level is, the larger the increase of the burned area is.","The higher the warming level is, the larger is the increase of burned area, ranging from~40% to~100% across the scenarios.","The higher the warming level is, the larger the increase of the burned area is. ""These results support the statement of the Paris Agreement (2015) that reports that limiting the temperature increase to 1.5oC would ""significantly reduce the risks and impacts of climate change,"" says the researcher. These fires caused economic and ecological losses, and even human casualties.","In any case, the burned area is robustly projected to increase. The higher the warming level is, the larger is the increase of burned area, ranging from~40% to~100% across the scenarios. Our results indicate that significant benefits would be obtained if warming were limited to well below 2°C.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37276271626&p=1pl&v=1&x=sVJ0ymJxyzXrlv2GI0KJ4A
10.1016/j.ajpath.2015.01.024,Biology_easy_409,"""Importantly, we found necrotizing myelitis and degeneration in the spinal cord, neurodegeneration in the dorsal root ganglia, and demyelination in the nerve roots only when lymphocytic inflammatory lesions were also observed in both the central nervous system and peripheral nervous system,"" stated Dr. Philipp.","Importantly, we found necrotizing myelitis and degeneration in the spinal cord, neurodegeneration in the DRG, and demyelination in the nerve roots only when lymphocytic inflammatory lesions were also observed in both the CNS and PNS.","Analyses of the differences in the mechanisms of action of both drugs may provide a blueprint for the development of new adjuvant treatments for LNB. ""Importantly, we found necrotizing myelitis and degeneration in the spinal cord, neurodegeneration in the dorsal root ganglia, and demyelination in the nerve roots only when lymphocytic inflammatory lesions were also observed in both the central nervous system and peripheral nervous system,"" stated Dr. Philipp. ""Our results suggest that ongoing cytokine activation in the nervous system can contribute to the persistent symptoms of fatigue, pain, and cognitive dysfunction that patients sometimes experience despite having been treated for Lyme disease.""","An association between changes in the latency of F-wave frequency, abnormal temporal dispersion, nerve conduction slowing, and the presence of demyelinating neuropathy or axonal damage was documented in several inflammatory demyelinating peripheral neuropathic disorders, including Guillain-Barré syndrome, and LNB. Importantly, we found necrotizing myelitis and degeneration in the spinal cord, neurodegeneration in the DRG, and demyelination in the nerve roots only when lymphocytic inflammatory lesions were also observed in both the CNS and PNS. Ongoing cytokine activation in the nervous system could contribute to the persistent symptoms of fatigue, pain, and cognitive dysfunction that patients sometimes experience despite having been treated for Lyme disease.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2015/04/150416084338.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2018.1807,Biology_easy_410,"""Each founding event, in fact, was achieved by a subpopulation carrying only a portion of the ancestral population's genetic diversity,"" the researchers suggest.","Each founding event, in fact, was achieved by a subpopulation carrying only a portion of the ancestral population's genetic diversity.","Instead, the random process of genetic drift meant that as human populations expanded further away from Africa and founded new continents, diversity in birth canals reduced as genetic diversity lessened. ""Each founding event, in fact, was achieved by a subpopulation carrying only a portion of the ancestral population's genetic diversity,"" the researchers suggest. ""The signature of these serial founding events is evident in modern populations' genetic variation, whereby genetic diversity decreases with increasing distance from Africa.""","The combination of a small founding population size and a quick dispersal meant that a series of genetic bottlenecks accompanied the colonization of new areas of the world. Each founding event, in fact, was achieved by a subpopulation carrying only a portion of the ancestral population's genetic diversity. The signature of these serial founding events is evident in modern populations' genetic variation, whereby genetic diversity decreases with increasing distance from Africa (and number of founding events in the population's history) .",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37491381304&p=1pl&v=1&x=J_qeWS5Av3SgZGjpwhwr5A
10.2337/db14-1225,Biology_easy_411,"aEURoeWe conclude that AMPK-STAT3 axis plays a pivotal role in regulating monocyte-to-macrophage differentiation and that AMPK activators by decreasing STAT3 phosphorylation through increased AMPK activity inhibit monocyte-to-macrophage differentiation,aEUR the authors write.","We conclude that the AMPK-STAT3 axis plays a pivotal role in regulating monocyte-to-macrophage differentiation and that by decreasing STAT3 phosphorylation through increased AMPK activity, AMPK activators inhibit monocyte-tomacrophage differentiation.","Increased AMPK activation with metformin and AICAR decreased STAT3 phosphorylation, causing inhibition of the differentiation of monocytes to macrophages. mice, metformin attenuated Ang-II-induced atheromatous plaque formation and aortic aneurysm, partly by decreasing infiltration of monocytes. aEURoeWe conclude that AMPK-STAT3 axis plays a pivotal role in regulating monocyte-to-macrophage differentiation and that AMPK activators by decreasing STAT3 phosphorylation through increased AMPK activity inhibit monocyte-to-macrophage differentiation,aEUR the authors write.","Metformin attenuated Ang-II-induced atheromatous plaque formation and aortic aneurysm in ApoE 2/2 mice partly by reducing monocyte infiltration. We conclude that the AMPK-STAT3 axis plays a pivotal role in regulating monocyte-to-macrophage differentiation and that by decreasing STAT3 phosphorylation through increased AMPK activity, AMPK activators inhibit monocyte-tomacrophage differentiation. AMPK activity was dose and time dependently downregulated during phorbol myristate acetate (PMA)-induced monocyteto-macrophage differentiation, which was accompanied by an upregulation of proinflammatory cytokine production.",[5],Biology,train,5.0,news,http://healthmedicinet.com/news/metformins-potential-role-in-atherosclerosis-explored/
10.1038/emi.2013.60,Biology_easy_412,"According to the paper, the towns and villages that constituted research sites for the study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside macaques accustomed to their presence.","The towns and villages that constituted research sites for our study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside synanthropic macaques.","Jones-Engel said long-term surveillance is needed in the areas where humans and primates come into contact since it's unlikely that SIV/HIV will be the last primate virus to emerge into the human population. According to the paper, the towns and villages that constituted research sites for the study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside macaques accustomed to their presence. The research team found that zoonotic transmission of SFV occurred most commonly through bites.","Human/NHP interface in Asia differs from that in Africa The data presented here expand our knowledge of cross-species transmission of SFV in Asia. The towns and villages that constituted research sites for our study are likely similar to hundreds or even thousands of sites throughout Asia, where humans live alongside synanthropic macaques. [1] [2] [] In contrast to Africa, where bushmeat hunting and habitat degradation threaten to deplete NHP populations over the next decades, 4, 5 some synanthropic primate populations in Asia have actually thrived, and continue to be sustainable, in spite of the pressures presented by increasing human populations.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2013/09/130904105343.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41467-019-08895-7,Biology_easy_413,"""These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between the ischemic heart and the remote bone marrow organ.""","These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between ischemic heart and the remote BM organ.","""Our work reveals that exosomes released from the ischemic heart are in fact mediating the systemic response of bone marrow progenitor cells to the site of injury,"" the researchers reported. ""These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between the ischemic heart and the remote bone marrow organ."" ""Because of the critical role of bone marrow progenitor cells in the ischemic tissue repair,"" they said, ""the mechanism identified in this study could be an important component of the physiological response to ischemic injury and thus could be leveraged for treatment of ischemic heart disease.""","Our work reveals that exosomes released from the ischemic heart are in fact mediating the systemic response of BM PCs to the site of injury. These observations are compelling, as circulating myo-miRs are not only a bio-marker, but also a functional constituent of the intricate crosstalk between ischemic heart and the remote BM organ. In this study we found exosomes mediate transfer of myo-miRs to BM.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38754070826&p=1pl&v=1&x=PCjC6TW6cIdpBWUFKRqAIA
10.1093/conphys/cot032,Biology_easy_414,"Dr Knapp says, ""The biological effects of altered biochemical concentrations may not be manifested over a short time period, but could have deleterious effects on long-term fitness and population stability.""","The biological effects of altered biochemical concentrations may not be manifested over a short time period, but could have deleterious impacts on long-term fitness and population stability.","Similarly, the higher uric acid levels in male and female iguanas could be the result of animal protein, such as ground beef, being fed to iguanas by tourists. Dr Knapp says, ""The biological effects of altered biochemical concentrations may not be manifested over a short time period, but could have deleterious effects on long-term fitness and population stability."" While the researchers acknowledge that increased population density as a result of tourist-feeding can be beneficial for endangered species, they warn that unnaturally high densities and excessive reliance on tourists for food may prove problematic if food supplementation is discontinued for any reason.","We stress the importance of this intra-specific comparison instead of solely evaluating published references. The biological effects of altered biochemical concentrations may not be manifested over a short time period, but could have deleterious impacts on long-term fitness and population stability. For example, food provisioning of garden birds can have important downstream consequences, such as smaller relative yolk mass in larger eggs and reduced yolk carotenoid concentrations in early breeders .",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2013/12/131205220120.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rspb.2014.0161,Biology_easy_415,"""This conflicts with the basic tenet that science neither rejects nor accepts anything without examining the evidence.",This conflicts with the basic tenet that science neither rejects nor accepts anything without examining the evidence.,"The study's authors are willing to give cryptozoologists their day in the sun. ""This conflicts with the basic tenet that science neither rejects nor accepts anything without examining the evidence. At first pass, this justification seems to open up a world of fascinating research.","Two Himalayan samples, one from Ladakh, India, the other from Bhutan, had their closest genetic affinity with a Palaeolithic polar bear, Ursus maritimus. This conflicts with the basic tenet that science neither rejects nor accepts anything without examining the evidence. , after analysis of a Nepalese sample, confirmed Captain Haddock's suspicions that the yeti was an ungulate [7] .",[5],Biology,train,5.0,news,http://www.thedailybeast.com/articles/2014/07/03/sorry-bigfoot-truthers-yetis-aren-t-real.html
10.1126/sciadv.aar8534,Biology_easy_416,"""Animal feed imports have increased 49 times, total ammonia and GHG emissions to the atmosphere doubled, and nitrogen losses to watercourses tripled,"" he adds.","In the same period, animal feed imports have increased 49 times, total ammonia and GHG emissions to the atmosphere doubled, and nitrogen losses to watercourses tripled.","""However, the costs of livestock transition are also large,"" says Lin Ma, the paper's corresponding author, also at the CAS institute. ""Animal feed imports have increased 49 times, total ammonia and GHG emissions to the atmosphere doubled, and nitrogen losses to watercourses tripled,"" he adds. ""This new transition must be induced by government, processing industry, consumers and retailers,"" stresses Ma.","Production of animal source protein increased 4.9 times, nitrogen use efficiency at herd level tripled, and average feed use and GHG emissions per gram protein produced decreased by a factor of 2 between 1980 and 2010. In the same period, animal feed imports have increased 49 times, total ammonia and GHG emissions to the atmosphere doubled, and nitrogen losses to watercourses tripled. Forecasts for 2050, using the Shared Socio-economic Pathways scenarios, indicate major further changes in livestock production and impacts.",[5],Biology,train,5.0,news,http://www.seeddaily.com/reports/Chinas_livestock_revolution_demands_new_transition_999.html
10.1038/nbt.2488,Biology_easy_417,Recon 2 will facilitate many future biomedical studies and is freely available here.,Recon 2 will facilitate many future biomedical studies and is freely available at http://humanmetabolism.org/.,"""The results provide a framework that will lead to a better understanding of how an individual's lifestyle, such as diet, or a particular drug they may require is likely to affect them according to their specific genetic characteristics,"" he added. ""The model takes us an important step closer to what is termed 'personalized medicine', where treatments are tailored according to the patient's genetic information."" Recon 2 will facilitate many future biomedical studies and is freely available here.",Mapping metabolomic data and drug information onto Recon 2 demonstrates its potential for integrating and analyzing diverse data types. Recon 2 will facilitate many future biomedical studies and is freely available at http://humanmetabolism.org/. r e s o u r c e of interest to the community of researchers focused on the systems biology of metabolism of a target organism.,[5],Biology,train,5.0,news,http://www.redorbit.com/news/health/1112795467/recon-metabolism-map-created-by-researchers-030413/
10.1016/j.cell.2018.05.009,Biology_easy_418,"""Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation.""",Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation.,"""Unexpectedly, we uncover a profound disruption of the circadian clock and diurnal transcriptome when hypoxic cells are permitted to acidify to recapitulate the tumor microenvironment,"" the article states. ""Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation."" The study's authors, led by Chi Van Dang, M.D., Ph.D., scientific director of the Ludwig Institute for Cancer Research, conclude that acid produced during the cellular metabolic response to hypoxia suppresses the circadian clock through diminished translation of clock constituents.","Unexpectedly, we uncover a profound disruption of the circadian clock and diurnal transcriptome when hypoxic cells are permitted to acidify to recapitulate the tumor microenvironment. Buffering against acidification or inhibiting lactic acid production fully rescues circadian oscillation. We find that acid drives peripheral redistribution of normally perinuclear lysosomes away from perinuclear RHEB, thereby inhibiting the activity of lysosome-bound mTOR.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34189804817&p=1pl&v=1&x=xIGbl9v-d2xQx6UL7EdZ5Q
10.1098/rspb.2017.1219,Biology_easy_419,It includes most of the giant species of titanosaurs and represents the major increase in body mass in the history of Titanosauria.,This clade includes most of the giant species of titanosaurs and represents the major increase in body mass in the history of Titanosauria.,"The team's analysis also revealed the presence of a previously unrecognized diverse lineage of Patagonian titanosaurs. It includes most of the giant species of titanosaurs and represents the major increase in body mass in the history of Titanosauria. ""The phylogenetic study we performed indicates that most of the giant titanosaurs known in Patagonia belong to a single lineage,"" Dr. Pol said.",Its inclusion in an extended phylogenetic analysis and the optimization of body mass reveals the presence of an endemic clade of giant titanosaurs inhabited Patagonia between the Albian and the Santonian. This clade includes most of the giant species of titanosaurs and represents the major increase in body mass in the history of Titanosauria. In addition to their taxonomic diversity (approx.,[5],Biology,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/mZxcd1LOqx8/patagotitan-mayorum-05121.html
10.1038/ncomms4406,Biology_easy_420,"However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors, and their deep energy level for electron conduction limits the open-circuit voltage.","However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors.","Secondly, high short-circuit currents were achieved by developing a multilayer device structure of three active semiconductor layers with complementary absorption spectra, and an efficient exciton harvesting mechanism. However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors, and their deep energy level for electron conduction limits the open-circuit voltage. Imec implemented two fullerene-free materials as acceptor, increasing open-circuit voltages compared to OPV cells with fullerene acceptors.","These results confirm that multilayer cascade structures are a promising alternative to conventional donor-fullerene organic solar cells. However, the small absorption overlap with the solar spectrum limits the photocurrent generation in fullerene acceptors. 17) , which is comparable to the best bilayer SubPc/C 60 cells reported in the literature 19 .",[5],Biology,train,5.0,news,http://www.nanowerk.com/nanotechnology_news/newsid=34710.php
10.1038/s41467-018-06124-1,Biology_easy_421,The process is suitable for the synthesis of free standing GaPO 4 nanosheets.,The developed printing process is also suitable for the synthesis of free standing GaPO 4 nanosheets.,"APPLICATIONS

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The new process is simple, scalable, low-temperature and cost effective, significantly expanding the range of materials available to industry at such scales and quality. The process is suitable for the synthesis of free standing GaPO 4 nanosheets. The low temperature synthesis method is compatible with a variety of electronic device fabrication procedures, providing a route for the development of future 2D piezoelectric materials.","The unit cell thick nanosheets present a large effective out-of-plane piezoelectric coefficient of 7.5 ± 0.8 pm V −1 . The developed printing process is also suitable for the synthesis of free standing GaPO 4 nanosheets. The low temperature synthesis method is compatible with a variety of electronic device fabrication procedures, providing a route for the development of future 2D piezoelectric materials.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37024124114&p=1pl&v=1&x=lMlK1R0_PaYXwsSegEUkBA
10.1111/1755-0998.12987,Biology_easy_422,"Because the concentration of eDNA in stream water results from both the amount of DNA shed by fish and the flow of water, the product of eDNA concentration and streamflow can be used to calculate absolute quantities of eDNA, Levi said.","Because the concentration of eDNA in streamwater results from both the amount of DNA shed by organisms and the flow of water, the product of eDNA concentration and streamflow (measured in units of water volume per time) can be used to calculate absolute quantities of eDNA per unit time.","""This is a major first step for more informed salmon management decisions because it opens up the possibility to affordably monitor many more streams than the few that are currently monitored."" Because the concentration of eDNA in stream water results from both the amount of DNA shed by fish and the flow of water, the product of eDNA concentration and streamflow can be used to calculate absolute quantities of eDNA, Levi said. The counts derived from eDNA were remarkably similar both for returning adult salmon and out-migrating juveniles"" Levi said.","than simply accumulating as fish enter a watershed, eDNA concentrations might spike up and down as a pulse of fish swims past a sampling point, with the size of the spike correlated with fish number and/or biomass. Because the concentration of eDNA in streamwater results from both the amount of DNA shed by organisms and the flow of water, the product of eDNA concentration and streamflow (measured in units of water volume per time) can be used to calculate absolute quantities of eDNA per unit time. If, for instance, juveniles rear sufficiently far upstream, the signal of their eDNA should be weak or undetectable, eliminating a source of noise that would prevent the robust enumeration of adult salmon entering lower stream reaches with eDNA.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38147506572&p=1pl&v=1&x=poM5RDff3I6ZMJ5l_Scmkg
10.1098/rspb.2015.1014,Biology_easy_423,"""Our discovery of this elastic tongue micropump could inspire applications, and the study of flow, in elastic-walled tubes in both biological and artificial systems,"" the scientists concluded.","Our discovery of this elastic tongue micropump could inspire applications, and the study of flow, in elastic-walled (flexible) tubes in both biological and artificial systems.","That energy subsequently facilitates the pumping of more nectar. ""Our discovery of this elastic tongue micropump could inspire applications, and the study of flow, in elastic-walled tubes in both biological and artificial systems,"" the scientists concluded. _____

Alejandro Rico-Guevara et al.","The new explanation of the mechanics of nectar uptake we provide here suggests that physical constraints are the main determinants of the relationship between pollinator type and nectar concentration, and can guide us through alternative hypotheses of hummingbird-flower coevolution. Our discovery of this elastic tongue micropump could inspire applications, and the study of flow, in elastic-walled (flexible) tubes in both biological and artificial systems. B 282: 20151014 entrance with respect to the nectar chamber.",[5],Biology,train,5.0,news,http://www.sci-news.com/biology/science-hummingbird-tongue-micropump-03146.html
10.7717/peerj.19,Biology_easy_425,Teller found that the sleight happened so quickly he himself did not realize he had loaded the cup.,"In fact, Teller found that the sleight happened so quickly he himself did not realize he had loaded the transparent cup.","The falling ball was so compelling that it drew his own attention away from his other hand, which was deftly and secretly loading a second ball under the glass. Teller found that the sleight happened so quickly he himself did not realize he had loaded the cup. He surmised he missed it because the falling ball captured his attention.","The falling ball was so compelling that it even drew his own attention away from his other hand, which was deftly and automatically loading a second ball under the glass (he was so well practiced that he no longer needed to consciously control his hands). In fact, Teller found that the sleight happened so quickly he himself did not realize he had loaded the transparent cup. Teller further realized that all of this took place despite the fact that he should have been able to see the secret ball as it was loaded under the cup.",[5],Biology,train,5.0,news,http://www.insidescience.org/content/ancient-magical-illusion-even-more-effective-magicians-may-realize/935
10.1126/sciadv.aaq0883,Biology_easy_426,"""We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies.",We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies.,"""Our results suggest that the alleged migrant crisis currently experienced by Europe is not likely to provoke an economic crisis but might rather be an economic opportunity,"" the researchers concluded. ""We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies. However, these political challenges may be more easily addressed if the cliche that international migration is associated with economic burden can be dispelled.""","Year 1 rather be an economic opportunity. We do not deny that large flows of asylum seekers into Europe pose many political challenges both within host countries and with respect to the European coordination of national policies. However, these political challenges may be more easily addressed if the cliché that international migration is associated with economic ""burden"" can be dispelled.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34353922261&p=1pl&v=1&x=HWJQ-179iZnBFBu4vGwVbw
10.1098/rsbl.2013.0120,Biology_easy_427,Further studies will build on this research to assess how widespread behavioural inheritance is for personality traits across other species.,Further studies are needed to assess how widespread this mode of inheritance is for personality traits across species.,"Although this study considers personality inheritance in zebra finches, it raises questions about the inheritance of personality in other species, including humans. The results of this study indicate that non-genetic transmission of behaviour can play an important role in shaping animal personality. Further studies will build on this research to assess how widespread behavioural inheritance is for personality traits across other species.","population density) vary predictably and stably across generations but not so long that genetically determined behaviours predominate. Our study provides evidence that personality traits can be nongenetically inherited, via behavioural transmission, in zebra finches. Further studies are needed to assess how widespread this mode of inheritance is for personality traits across species.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2013/06/130605090524.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1126/science.aan2329,Biology_easy_428,"""This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria.""",This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria.,"""The geological context, including at least four levels with embryos and eggs, indicates that this deposit was formed by a rare combination of events, with storms acting on a nesting ground,"" researchers reported in their study. ""This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria."" ''The work is a crucial advance in understanding pterosaur reproduction,'' said Charles Deeming, from the University of Lincoln.","The geological context, including at least four levels with embryos and eggs, indicates that this deposit was formed by a rare combination of events, with storms acting on a nesting ground. This discovery supports colonial nesting behavior and potential nesting site fidelity in the Pterosauria. The specimens can be attributed to Hamipterus tianshanensis, the sole species in this bonebed.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=32659471801&p=1pl&v=1&x=O3ePTt4rZsKTDZMm6Zr1VA
10.1016/j.nutres.2019.03.004,Biology_easy_429,RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption.,RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption.,Pathological studies confirmed that lumps were breast cancer in all women who remained in the trial. RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption. Ingenuity Pathway Analysis showed activation of pathways that promote apoptosis and cell adhesion and inhibition of pathways that promote cell proliferation and migration.,"Pathological studies confirmed that lumps were breast cancer in all women who remained in the trial. RNA sequencing expression profiling revealed that expression of 456 identified genes was significantly changed in the tumor due to walnut consumption. Ingenuity Pathway Analysis showed activation of pathways that promote apoptosis and cell adhesion, and inhibition of pathways that promote cell proliferation and migration.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38864633495&p=1pl&v=1&x=9kb1spTs1kP4Fpl1LuDBvQ
10.1002/stem.2883,Biology_easy_431,"""Overall, our study affirms that light-responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at a scale needed for pharmacology and drug screening purposes.""",Together our data indicate that light responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at the scale needed for pharmacology and drug screening purposes.,"""Seeding density and nutrient availability seemed to have had the most dominant effect on retinal organoid formation. ""Overall, our study affirms that light-responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at a scale needed for pharmacology and drug screening purposes."" By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices.","We tested the response of iPSC-derived retinal organoids to Moxifloxacin and showed that similarly to in vivo adult mouse retina, the primary affected cell types were photoreceptors. Together our data indicate that light responsive retinal organoids derived from carefully selected and differentiation efficient iPSC lines can be generated at the scale needed for pharmacology and drug screening purposes. Hallam and colleagues show herein that generation of retinal organoids from human iPSC is efficient, reliable and scalable.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34736794934&p=1pl&v=1&x=kDwuobeOawEn0gntPOc4ng
10.1128/jb.01589-14,Biology_easy_432,"The results reinforce the notion that survival after high doses of ionizing radiation does not depend on a single mechanism or process, but instead is multifaceted.","The results reinforced the notion that survival after high doses of ionizing radiation does not depend on a single mechanism or process, but instead is multifaceted.","The 46 genes did not result from the mutations created under high radiation levels, but rather genes that exist in the normal, wild-type E. coli. The results reinforce the notion that survival after high doses of ionizing radiation does not depend on a single mechanism or process, but instead is multifaceted. ""We established a role for genes involved in processes as diverse as central metabolism and the synthesis and maintenance of the cell wall in radiation survival,"" says Cox.","Forty-six genes were identified, most of which become essential upon heavy IR exposure. The results reinforced the notion that survival after high doses of ionizing radiation does not depend on a single mechanism or process, but instead is multifaceted. However, contributions by genes involved in cell wall structure/function, cell division, and intermediary metabolism were also evident.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/07/140721123825.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-019-09945-w,Biology_easy_433,Yield increase is therefore shown to be more effective in reducing land use when combined with land use regulation and consumption changes.,Yield increase is therefore shown to be more effective in reducing land use when combined with land-use regulation and consumption changes.,"The study adds an extra level of understanding to how the different options above interact, and how best to combine them. Yield increase is therefore shown to be more effective in reducing land use when combined with land use regulation and consumption changes. The researchers say that the study is an important milestone for the research community as it will help to elaborate more consistent quantitative scenarios across studies, and ease the comparability of results for policy guidance on all major sustainability challenges related to land use, including climate change impact and mitigation, biodiversity, and food security.","Furthermore, this study adds an analysis of interactions between factors: an increase in agricultural efficiency can reduce demand for cropland but can also trigger higher demand. Yield increase is therefore shown to be more effective in reducing land use when combined with land-use regulation and consumption changes. Consumption changes, better land management, and increased agricultural productivity therefore appear robust and effective measures to reduce the demand for agricultural land, in particular when bundled together.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=39240053352&p=1pl&v=1&x=b5ez99X_WY5QWY7Dbe1_4g
10.1038/s41556-019-0333-2,Biology_easy_434,"Our pathway-inhibition paradigm thus opens an avenue for generating mammalian pluripotent stem cells, and EPSCs present a unique cellular platform for translational research in biotechnology and regenerative medicine.""","Our pathway-inhibition paradigm thus opens an avenue for generating mammalian pluripotent stem cells, and EPSCs present a unique cellular platform for translational research in biotechnology and regenerative medicine.","Importantly, trophoblast stem-cell-like cells can be generated from both human and porcine EPSCs. Our pathway-inhibition paradigm thus opens an avenue for generating mammalian pluripotent stem cells, and EPSCs present a unique cellular platform for translational research in biotechnology and regenerative medicine."" The study is the first time scientists have been able to derive stem cells from early pig embryos, noted the scientists.","Importantly, trophoblast stem-cell-like cells can be generated from both human and porcine EPSCs. Our pathway-inhibition paradigm thus opens an avenue for generating mammalian pluripotent stem cells, and EPSCs present a unique cellular platform for translational research in biotechnology and regenerative medicine. Our results demonstrate that porcine EPSCs could be established and, importantly, that similar culture conditions permit derivation of human EPSCs.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=39384948574&p=1pl&v=1&x=kJohdbe65Giukna_tHVVgg
10.1186/s12974-019-1453-0,Biology_easy_435,"Nonetheless, the immune response is deeply tied to the development of pathology, and with advancing technologies, we are able to more fully dissect the complexity of this response and the effector cells that carry it out.","Nonetheless, the immune response is deeply tied to the development of pathology, and with advancing technologies, we are able to more fully dissect the complexity of this response and the effector cells that carry it out.","These peripheral immune cells can aid in amyloid b clearance or modulate microglia responses, depending on the cell type. Nonetheless, the immune response is deeply tied to the development of pathology, and with advancing technologies, we are able to more fully dissect the complexity of this response and the effector cells that carry it out. Our knowledge of how microglia and peripheral immune cells interact has proved invaluable in understanding how this delicate balance goes awry in disease.","Treatment of amyloidogenic murine models with pioglitazone, a direct agonist of PPARγ, reduces amyloid β 1-42 deposits in the hippocampus . Nonetheless, the immune response is deeply tied to the development of pathology, and with advancing technologies, we are able to more fully dissect the complexity of this response and the effector cells that carry it out. Our knowledge of how microglia and peripheral immune cells interact has proved invaluable in understanding how this delicate balance goes awry in disease.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38978630439&p=1pl&v=1&x=9aaycFjKC6olbnBiXp14ng
10.1126/sciadv.1501675,Biology_easy_436,"""This suggests that if future habitat loss is prevented, the tiger recovery in some range states will accelerate.","This suggests that if future habitat loss is prevented, the tiger recovery now underway in some range states will accelerate.","""Most encouraging was that loss was less than expected in the 51 tiger reserves,"" wrote the authors in the paper. ""This suggests that if future habitat loss is prevented, the tiger recovery in some range states will accelerate. In these promising locales of enhanced protection, a doubling of the tiger population could be attainable by 2022.""","Most encouraging was that loss was less than expected in the 51 tiger reserves that serve as source sites in the priority landscapes. This suggests that if future habitat loss is prevented, the tiger recovery now underway in some range states will accelerate. In these promising locales of enhanced protection, a doubling of the tiger population could be attainable by 2022.",[5],Biology,train,5.0,news,http://www.redorbit.com/news/science/1113413447/could-tiger-populations-recover-these-scientists-say-yes-040316/
10.1016/j.vaccine.2014.05.010,Biology_easy_437,This finding is consistent with the fact that the spleen is amongst the most important organs for filtering out foreign agents and is the main organ for antigen presentation in teleost fish.,This finding is consistent with the fact that the spleen is amongst the most important organs for filtering out foreign agents and is the main organ for antigen presentation in teleost fish .,"This finding is consistent with the fact that the spleen is amongst the most important organs for filtering out foreign agents and is the main organ for antigen presentation in teleost fish. The level of protection observed in the fish treated with NLc liposomes, regardless of the administration route, suggests the potential utility of these liposomes as a broad-spectrum tool for immunological protection of fish. Furthermore, the fact that the mixture of free immunostimulants did not offer protection in any of the infection models underscores the importance of encapsulating in liposomes to ensure optimal activation of the immune system.","injection clearly indicated that the spleen was the main organ in which the liposomes had accumulated. This finding is consistent with the fact that the spleen is amongst the most important organs for filtering out foreign agents and is the main organ for antigen presentation in teleost fish . Furthermore, with NLc liposomes were also challenged with PAO1 one month after immunostimulation.",[5],Biology,train,5.0,news,http://www.nanowerk.com/nanotechnology-news/newsid=36056.php
10.1021/cb4008953,Biology_easy_438,"""This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum,"" they state.",This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum.,"This resensitizes the parasites to chloroquine, and appears to block the normal function of the resistance protein, killing the parasite. ""This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum,"" they state.","Moreover, the additional parasiticidal effect exerted by 1 and 6 in the drug-resistant parasites was attributable, at least in part, to their ability to inhibit PfCRT CQR . This highlights the potential for devising new antimalarial therapies that exploit inherent weaknesses in a key resistance mechanism of P. falciparum. This phenomenon is thought to be due to an increase in the efflux of the drug from the DV, a decrease in its uptake into the DV, or a combination of both.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/01/140115122211.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.cub.2014.10.014,Biology_easy_440,"'In my opinion, the more subtle perspective we offer could have important implications for decision-making in both the boardroom and the classroom.",The more subtle perspective we offer could have important implications for decision making in both the boardroom and the classroom.,"'It shows the positive side of social dominance.' 'In my opinion, the more subtle perspective we offer could have important implications for decision-making in both the boardroom and the classroom. For example if you are trying to help a leader to learn something new it may be important to consider whether they are socially or aggressively dominant, and whether they will best learn via a social or individual route.'","This paper presents the first study of dominance and social learning in humans and challenges the lay stereotype in which all dominant individuals ignore others' views . The more subtle perspective we offer could have important implications for decision making in both the boardroom and the classroom. In experiment 1, adult participants (n = 33; age mean = 27.88, SEM = 1.39; 19 males, 14 females; Table S1 available have demonstrated that individuals who score high in either SD or AD, on the scales we employed, have strong beliefs about the importance of individual accountability and self-report high levels of self-esteem, authoritarianism, and self-sufficiency .",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/11/141120123051.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41467-018-04863-9,Biology_easy_441,"PRMT5 pharmacological inhibition, CRISPR-cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation.","PRMT5 pharmacological inhibition, CRISPR/cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation.","PRMT5 pharmacological inhibition, CRISPR-cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation. Conditional ablation of Prmt5 in progenitors results in hypomyelination, reduced survival, and differentiation. ""Data obtained using purified histones further validate the results obtained in mice and in cultured oligodendrocyte progenitors.","PRMT5 pharmacological inhibition, CRISPR/cas9 targeting, or genetic ablation decrease p53-dependent survival and impair differentiation without affecting proliferation. Conditional ablation of Prmt5 in progenitors results in hypomyelination, reduced survival and differentiation. Decreased histone H4R3 symmetric methylation is followed by increased nuclear acetylation of H4K5, and is rescued by pharmacological inhibition of histone acetyltransferases.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34581587669&p=1pl&v=1&x=ItNrPiAOfGTQKOiU8pm4UA
10.1093/icesjms/fsw166,Biology_easy_442,"""Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, but they also highlight the importance of investigating multi-species interactions, as the recovery of some species can have knock-on effects on others,"" says Bryce Beukers-Stewart, a lecturer in the University of York's environment department and supervisor of the study.","Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, and highlight the importance of investigating multispecies interactions, as the recovery of some species can have knock-on effects on others.","This could be due to the relatively small size of the Lamlash Bay reserve, showing that larger reserves are needed to allow marine ecosystems to recover more naturally. ""Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, but they also highlight the importance of investigating multi-species interactions, as the recovery of some species can have knock-on effects on others,"" says Bryce Beukers-Stewart, a lecturer in the University of York's environment department and supervisor of the study. However, our research within Lamlash Bay has shown that a wide range of species and habitats can benefit from protection.","Interestingly, catches of adult lobsters were inversely correlated with those of juvenile lobsters, brown crabs, and velvet crabs, which may be evidence of competitive displacement and/or predation. Our findings provide evidence that temperate marine reserves can deliver fisheries and conservation benefits, and highlight the importance of investigating multispecies interactions, as the recovery of some species can have knock-on effects on others. If populations are to benefit from the protection afforded by MPAs, it is necessary that a number of individuals spend a substantial part of their lives within their boundaries .",[5],Biology,train,5.0,news,http://www.futurity.org/marine-reserve-lobsters-1261382-2/
10.1007/s00125-016-4065-6,Biology_easy_443,The patients in the intensive-therapy group survived for a median of eight years longer than the conventional-therapy group patients.,The patients in the intensivetherapy group survived for a median of 7.9 years longer than the conventional-therapy group patients.,"Longer lives

At the follow-up 21 years after the initiation of the study, 38 intensive-therapy patients versus 55 conventional-therapy patients had died (meaning the original intensively treated patients were 45 percent less likely to die). The patients in the intensive-therapy group survived for a median of eight years longer than the conventional-therapy group patients. Importantly, median time before first cardiovascular event after randomization was also eight years longer in the original intensive-therapy group meaning that the additional eight years of life is likely to correspond to the extra eight years free of new cardiovascular complications.","Results Thirty-eight intensive-therapy patients vs 55 conventional-therapy patients died during follow-up (HR 0.55 [95% CI 0.36, 0.83], p = 0.005). The patients in the intensivetherapy group survived for a median of 7.9 years longer than the conventional-therapy group patients. Median time before first cardiovascular event after randomisation was 8.1 years longer in the intensive-therapy group (p = 0.001).",[5],Biology,train,5.0,news,http://www.futurity.org/diabetes-microalbuminura-1245772-2/
10.1098/rsbl.2017.0299,Biology_easy_445,"The research suggests, in contrast to expectations, ""the rapid global range expansion of true frogs was not associated with increased net-diversification.""","Interestingly, and in striking contrast to expectations, the rapid global range expansion of true frogs was not associated with increased net diversification.","Not so for ""true frogs,"" the research indicates. The research suggests, in contrast to expectations, ""the rapid global range expansion of true frogs was not associated with increased net-diversification."" ""We found a distinct pattern.","We detected no shifts in extinction rates, nor signatures of mass extinction (electronic supplementary material, figure S3 ). Interestingly, and in striking contrast to expectations, the rapid global range expansion of true frogs was not associated with increased net diversification. On the contrary, diversification rates either decreased or remained unchanged, even as remarkable, circumglobal range expansion via dispersal and colonization of novel regions occurred.",[5],Biology,train,5.0,news,http://www.futurity.org/true-frogs-evolution-1546132/
10.1016/j.devcel.2014.11.012,Biology_easy_446,"The researchers also found that senescent cells were present only for a short time during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues.","Notably, senescent cells were present only transiently during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues.","""It rescued delayed wound closure and allowed the mice to heal normally."" The researchers also found that senescent cells were present only for a short time during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues. Moreover, they say the fact that PDGF-AA was activated very early upon senescence induction in cell culture suggests the time-dependent regulation of secretory factors might, in part, explain the beneficial vs. deleterious effects of senescent cells.","In contrast to the well-documented deleterious effects of senescent cells and the SASP, the results presented here unambiguously demonstrate a positive role for senescent cells and the SASP in tissue repair. Notably, senescent cells were present only transiently during tissue repair, in contrast to the persistent presence of senescent cells in aged or chronically damaged tissues. Moreover, PDGF-A was induced very early upon senescence induction in cell culture, suggesting the time-dependent regulation of SASP factors might in part explain the beneficial versus deleterious effects of senescent cells.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/12/141211124526.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1073/pnas.1220333110,Biology_easy_447,"The authors write: ""In addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities.""","Thus, in addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities.","""A mix of meadows, young forest, old forest and shrub lands, for example, might provide more benefits than a landscape of continuous young forest, even if that young forest itself has high biodiversity,"" Zavaleta said. The authors write: ""In addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities."" ""What's new here,"" Zavaleta says, ""is reminding us that it's not just important to protect a diversity of species but also important to protect the mosaic of habitat patches in a landscape.""","Higher β diversity also reduced the variability in multifunctionality. Thus, in addition to conserving important species, maintaining ecosystem multifunctionality will require diverse landscape mosaics of diverse communities. The effects of individual species (3-5) and α diversity (6) also become stronger as more functions are considered simultaneously (ecosystem multifunctionality).",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2013/06/130607160335.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41556-018-0178-0,Biology_easy_449,"""We showed that BAP1 inhibits tumor development partly through SLC7A11 and ferroptosis and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis,"" said Gan.","Furthermore, we show that BAP1 inhibits tumour development partly through SLC7A11 and ferroptosis, and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis.","They also discovered that BAP1 promotes ferroptosis by mediating repression of a cystine 'transporter' called SLC7A11. ""We showed that BAP1 inhibits tumor development partly through SLC7A11 and ferroptosis and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis,"" said Gan. ""Together, our results uncover a previously unappreciated mechanism coupling ferroptosis to tumor suppression.""","Here, integrated transcriptomic, epigenomic and cancer genomic analyses link BAP1 to metabolismrelated biological processes, and identify cystine transporter SLC7A11 as a key BAP1 target gene in human cancers. Furthermore, we show that BAP1 inhibits tumour development partly through SLC7A11 and ferroptosis, and that cancer-associated BAP1 mutants lose their abilities to repress SLC7A11 and to promote ferroptosis. Together, our results uncover a previously unappreciated epigenetic mechanism coupling ferroptosis to tumour suppression.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37064060364&p=1pl&v=1&x=a2fTxH3Rplcv8Uzwlz6SoQ
10.1038/s41467-018-05774-5,Biology_easy_450,The variation of the composition of the oxides allows tailoring the Li-storage properties of the active material.,The variation of the composition of the oxides allows tailoring the Li-storage properties of the active material.,"In this study, to our knowledge for the first time, it is shown that high entropy oxides are very promising materials for reversible electrochemical energy storage. The variation of the composition of the oxides allows tailoring the Li-storage properties of the active material. The incorporation of different elements into HEO offers a modular approach for the systematic design of the electrode material.","In this study, to our knowledge for the first time, it is shown that high entropy oxides are very promising materials for reversible electrochemical energy storage. The variation of the composition of the oxides allows tailoring the Li-storage properties of the active material. The incorporation of different elements into HEO offers a modular approach for the systematic design of the electrode material.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=37351463959&p=1pl&v=1&x=BzCmGEWEgoP1VMlqm7np_g
10.1038/s41467-019-10373-z,Biology_easy_452,"""Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonizing a wide range of environments,"" scientists wrote in their paper.","Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonising a wide range of environments.","The study results, published this week in the journal Nature Communications, showed microbial communities in soil across the globe are dominated by the same few species. ""Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonizing a wide range of environments,"" scientists wrote in their paper. Researchers suggests an improved understanding of microbial distribution across global soils and ecosystems can aid conservation efforts.","Our findings indicate that 83 phylotypes (<0.1% of the retrieved fungi), mostly belonging to wind dispersed, generalist Ascomycota, dominate soils globally. Whole-genome comparisons with less dominant, generalist fungi point at a significantly higher number of genes related to stress-tolerance and resource uptake in the dominant fungi, suggesting that they might be better in colonising a wide range of environments. Our findings constitute a major advance in our understanding of the ecology of fungi, and have implications for the development of strategies to preserve them and the ecosystem functions they provide.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=39357877793&p=1pl&v=1&x=Dt5iT9DrdF2l58oRR6ph9g
10.1098/rsbl.2017.0656,Biology_easy_453,"""Our measurements likely underestimate the soundscape potential of the event, given the intense, persistent fishing activity that has greatly reduced the size of the adult population,"" the authors explained.","Notably, our measurements likely underestimate the soundscape potential of the event, given the intense, persistent fishing activity that has greatly reduced the size of the adult population .","In fact, if it weren't for overfishing, the fish chorus would probably be even louder. ""Our measurements likely underestimate the soundscape potential of the event, given the intense, persistent fishing activity that has greatly reduced the size of the adult population,"" the authors explained. Erisman and Rowell warned that fishing is actually damaging the unique marine event.","The chorus of the aggregation can elevate the local soundscape 21 times louder than ambient levels, making these unique acoustic behavioural events a true wildlife spectacle. Notably, our measurements likely underestimate the soundscape potential of the event, given the intense, persistent fishing activity that has greatly reduced the size of the adult population . crickets and frogs) [31] , the loud sounds produced by male corvina during spawning may facilitate communication among potential mates in a noisy environment made even noisier by the synchronous chorusing of conspecifics (i.e.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=32827188427&p=1pl&v=1&x=s1a6sJtO1c-BRdsIlYQRsQ
10.1038/ncomms4635,Biology_easy_455,"The study found that the most important approach to the earliest possible detection of a significant sea level acceleration lies in improved understanding (and subsequent removal) of interannual (occurring between years, or from one year to the next) to multidecadal (involving multiple decades) variability in sea level records.",We find that the most important approach to earliest possible detection of a significant sea level acceleration lies in improved understanding (and subsequent removal) of interannual to multidecadal variability in sea level records.,"Scientists should continue to update the analysis every 5 to 10 years, creating more certainty in long-term planning -- and helping develop solutions for a changing planet."" The study found that the most important approach to the earliest possible detection of a significant sea level acceleration lies in improved understanding (and subsequent removal) of interannual (occurring between years, or from one year to the next) to multidecadal (involving multiple decades) variability in sea level records. Such processes introduce a large amount of 'noise' into the record, masking any underlying acceleration in the rate of rise.","We find that the most important approach to earliest possible detection of a significant sea level acceleration lies in improved understanding (and subsequent removal) of interannual to multidecadal variability in sea level records. The lower end is broadly consistent with linear continuation of the average rate of rise observed over the 0th century , while the upper value (and larger projected rises ) requires a significant increase (that is, an acceleration) on the average 0th century rate. Earliest possible detection of a significant increase in the rate of sea level rise is helpful to inform the public and support direct political action to enable adequate adaptation , particularly for projections with higher rates of rise.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/05/140509074116.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1420105111,Biology_easy_456,"""Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines.""",Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines.,"While UV light has limitations in its ability to penetrate tissue, the researchers suggest that leveraging infrared light -- which has greater penetration depths -- or introducing UV light via endoscopy are areas for further exploration. ""The importance of this research is in the demonstration of the spatiotemporal regulation of aptamer activity in vitro and in vivo that can be achieved by a photo-triggered strategy,"" says Lele Li, one of the paper's lead authors. ""Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines.""","Furthermore, the relative distribution of the aptamer to the tumor was enhanced in relation to uptake by the liver and kidneys. Our strategy may provide an approach to improving the therapeutic indices of aptamer-based medicines. (Fig.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/12/141203151804.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/s10530-016-1101-x,Biology_easy_459,"Although their impacts are small compared to those of rodents, earthworms may act as significant predators of some seeds, especially those too small to be preferred by vertebrates.","Our results suggest that although their impacts generally are small compared to those of rodents, earthworms may act as significant predators of some seeds, particularly those too small to be preferred by vertebrates.","Kotanen says the results suggest that earthworms could be having a greater impact on temperate forest plant life than previously imagined. Although their impacts are small compared to those of rodents, earthworms may act as significant predators of some seeds, especially those too small to be preferred by vertebrates. ""Seeds that are safe from rodents may be vulnerable to worms.","This is the first earthworm exclosure field experiment of which we are aware. Our results suggest that although their impacts generally are small compared to those of rodents, earthworms may act as significant predators of some seeds, particularly those too small to be preferred by vertebrates. Species with eliaosomes were not used so as to mitigate any effect of myrmecochory.",[5],Biology,train,5.0,news,http://www.futurity.org/invasive-species-earthworms-seeds-1158392-2/
10.1016/j.cell.2013.12.021,Biology_easy_461,"""The findings indicate that PRDM16 and beige adipocytes [fat cells] are required for the 'browning' of white fat and the healthful effects of subcutaneous adipose tissue,"" said the authors.",These findings indicate that PRDM16 and beige adipocytes are required for the ''browning'' of white fat and the healthful effects of subcutaneous adipose tissue.,"""The findings indicate that PRDM16 and beige adipocytes [fat cells] are required for the 'browning' of white fat and the healthful effects of subcutaneous adipose tissue,"" said the authors. In the future, the discovery ""might lead to pharmacologic strategies to treat obesity-related diseases,"" said Cohen, the study's first author. ""The goal would be to create healthier fat,"" possibly by manipulating PRDM16 in the body, he said.",Transplantation of subcutaneous fat into mice with diet-induced obesity showed a loss of metabolic benefit when tissues were derived from PRDM16 mutant animals. These findings indicate that PRDM16 and beige adipocytes are required for the ''browning'' of white fat and the healthful effects of subcutaneous adipose tissue. The location where fat is deposited appears to have a great influence on the likelihood of an individual developing many of the sequelae of obesity .,[5],Biology,train,5.0,news,http://www.technology.org/2014/01/18/beige-fat-cells-key-healthier-fat/
10.1098/rsbl.2013.0620,Biology_easy_462,"The research suggests that cheetah chases comprise two primary phases, the first an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by a second, which is a prey-specific slowing period, five to eight seconds before the end of the chase, that enables the cheetah to match turns instigated by prey as the distance between them closes.","Rather, we suggest that cheetah chases comprise two primary phases: (i) an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by (ii) a prey-specific slowing period that enables the cheetah to match turns instigated by prey as the distance between them closes.","Basically, cheetahs have clear different chase strategies depending on prey species."" The research suggests that cheetah chases comprise two primary phases, the first an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by a second, which is a prey-specific slowing period, five to eight seconds before the end of the chase, that enables the cheetah to match turns instigated by prey as the distance between them closes. advertisement

Dr Scantlebury added: ""We have discovered that cheetahs first accelerate rapidly to get them close to the prey but then have to actively slow down to be able to match prey escape manoeuvres.","Thus, the widely held belief that cheetah hunts consist of simple highspeed chases seems an oversimplification. Rather, we suggest that cheetah chases comprise two primary phases: (i) an initial rapid acceleration resulting in high speed to quickly catch up with prey, followed by (ii) a prey-specific slowing period that enables the cheetah to match turns instigated by prey as the distance between them closes. However, this formulation only considered forward acceleration and speed, ignoring lateral acceleration.",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2013/09/130905085644.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.immuni.2018.03.027,Biology_easy_463,The results support the model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation.,These data support a model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation.,"The researchers also noted the expression of the proteins ICAM-1 and SLAM in Bcl6loCD69hi cells was higher than in Bcl6hiCD69hi cells, therefore affording more stable Tfh-GC B cell contacts. The results support the model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation. ""Our data not only provided important information for vaccines development, but also open up new doors for further study,"" study corresponding author Tomohiro Kurosaki says.","hi CD69 hi cells, thereby affording more stable T follicular helper (Tfh)-GC B cell contacts. These data support a model whereby commitment to the plasma cell begins in the GC and suggest that stability of Tfh-GC B cell contacts is key for plasma cell-prone GC cell formation. Higher expression of ICAM-1 and SLAM in those cells facilitates more stable contacts with Tfh cells, suggesting that strength of Tfh-GC B cell interaction critically regulates formation of plasma cell precursors.",[5],Biology,train,5.0,news,http://healthmedicinet.com/news/accepted-or-rejected-uncovering-how-fate-of-b-cell-is-determined/
10.1038/s41467-018-04334-1,Biology_easy_464,"Understanding the origins of breast cancer, in its earliest phases, has the potential to improve methods of early cancer detection and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease.","Understanding the origins of breast cancer in its earliest phases has the potential to advance methods of cancer early detection, and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease.","The scRNAseq technology enabled the recognition of previously unseen cellular differences. Understanding the origins of breast cancer, in its earliest phases, has the potential to improve methods of early cancer detection and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease. Our discovery of the three epithelial cell populations closes some of those gaps and may help us understand how the system goes awry during breast cancer,"" said Kessenbrock.","Instead, the outcome of our Monocle analysis is in favor of the existence of the bi-potent stem/progenitor model as it clearly identified one continuous trajectory indicative of a common source for both basal and luminal cell differentiation. Understanding the origins of breast cancer in its earliest phases has the potential to advance methods of cancer early detection, and may ultimately form the basis to prevent cancer progression before it turns into a life-threatening disease. The luminal epithelial cell type L2 showed the clearest correlation with both Luminal A and B subtypes from the Metabric dataset , which is in line with previously reported similarities between a FACS-enriched population of mature luminal cells and the luminal-like breast cancer subtypes .",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34194160481&p=1pl&v=1&x=glfjQQBYAgvsXALLyNHWTA
10.1038/s41467-018-07921-4,Biology_easy_466,"This immediate carbon loss is partially compensated by a boost in new ecosystem productivity, driven by changes to canopy composition and soil respiration.",This immediate carbon loss is partially compensated by an enhancement in net ecosystem productivity driven by changes in canopy composition and soil respiration 2 .,"Globally, over the past decade, fire ozone pollution reduced plant productivity substantially more than estimated drought losses."" This immediate carbon loss is partially compensated by a boost in new ecosystem productivity, driven by changes to canopy composition and soil respiration. It found that the Gross Primary Productivity (GPP) -- essentially plant photosynthesis -- was significantly reduced when the amount of surface ozone increases.","This immediate carbon loss is partially compensated by an enhancement in net ecosystem productivity driven by changes in canopy composition and soil respiration 2 . Regionally, fires can enhance surface O 3 by 10-30 ppbv 6,7 during pollution episodes and dominate PM 2.5 with average contributions of 30-55% 9 during fire seasons. Increases in O 3 and aerosols have strongly contrasting impacts on plant productivity 12 .",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=38047416961&p=1pl&v=1&x=YiUs3rlv4tmSANobcl3ieA
10.1038/s41467-017-00962-1,Biology_easy_467,"The researchers identified sequence changes in the TP53 tumor suppressor gene, a well-known driver gene in HGSOC, in all the patients.","As expected, we identified sequence changes in the TP53 tumor suppressor gene, a wellknown driver gene in HGSOC, in all cases.","""It points us to a signature in the tubes to look for, and shows us a window of time to spot these cancers before they morph into something more sinister in the ovaries."" The researchers identified sequence changes in the TP53 tumor suppressor gene, a well-known driver gene in HGSOC, in all the patients. Those alterations were identical in all the samples from the same patient, including in the p53 (a tumor protein) signatures, the STIC lesions, and other carcinomas, suggesting that mutation of TP53 was among the earliest initiating events for HGSOC development, the authors said.","Whole-exome sequence analyses of the tumor samples from each patient identified somatic mutations that were present in all neoplastic samples analyzed as well as specific changes that were present in individual or subsets of tumors (Fig. As expected, we identified sequence changes in the TP53 tumor suppressor gene, a wellknown driver gene in HGSOC, in all cases. The TP53 alterations were identical in all samples analyzed for each patient including in the p53 signatures, the STIC lesions, and other carcinomas.",[5],Biology,train,5.0,news,http://healthmedicinet.com/news/mutation-in-fallopian-tube-lesions-may-help-catch-ovarian-cancer-years-earlier/
10.1038/s41467-018-05970-3,Biology_easy_468,They found the hydrophobic gating mechanism is also consistent with scanning mutagenesis studies showing that modulation of pore hydrophobicity is correlated with activation properties.,The hydrophobic gating mechanism is also consistent with scanning mutagenesis studies showing that modulation of pore hydrophobicity is correlated with activation properties.,"Initiation of dewetting transitions in BK channels requires changes in the pore shape and surface hydrophobicity driven by calcium binding. They found the hydrophobic gating mechanism is also consistent with scanning mutagenesis studies showing that modulation of pore hydrophobicity is correlated with activation properties. He adds, ""Our data reconciles key results from previous experimental studies without invoking any crazy ideas.","Importantly, the dry pore remains physically open and is readily accessible to quaternary ammonium channel blockers. The hydrophobic gating mechanism is also consistent with scanning mutagenesis studies showing that modulation of pore hydrophobicity is correlated with activation properties. BK channels are great model systems for understanding gating mechanisms of ion channels.",[5],Biology,train,5.0,news,http://ct.moreover.com/?a=34905322201&p=1pl&v=1&x=-NM0Kc2wPAJ0_5fmDnQ34g
10.3389/fonc.2014.00045,Biology_easy_469,"""Given these results, it is possible that TAF2 overexpression could increase transcription of C-SRC in some ovarian tumors,"" the researchers wrote.","Given these results, it is possible that TAF2 overexpression could increase transcription of C-SRC in some ovarian tumors.","Cell growth and death

Meanwhile, TAF2 may have its own cancer-related modus operandi. ""Given these results, it is possible that TAF2 overexpression could increase transcription of C-SRC in some ovarian tumors,"" the researchers wrote. There, too, there is a suspicious mechanistic connection to ovarian cancer.","demonstrate that the TAF1/TAF2 complex binds C-SRC 5 exon promoters, which are TATA-less and contain Inr sequences . Given these results, it is possible that TAF2 overexpression could increase transcription of C-SRC in some ovarian tumors. Reminiscent of the TFIID-independent function of TAF3 in regulation of myogenesis , the transcriptional control of Inr-containing promoters by TAF1/TAF2 may be relevant in ovarian cancer, since TBP is predominantly downregulated in many HGSCs (2, 3).",[5],Biology,train,5.0,news,http://www.sciencedaily.com/releases/2014/03/140313134356.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41589-018-0130-4,Biology_easy_470,"In the case of the TCR studied in the current research, DMF5, researchers knew it recognized hydrophobic peptide antigens, which are water-insoluble.","The displacement is maximal at Ala150, widening the binding groove by 2 Å at this point.","Scientists knew there were many millions more peptides, or antigen targets, than TCRs. In the case of the TCR studied in the current research, DMF5, researchers knew it recognized hydrophobic peptide antigens, which are water-insoluble. Garcia noticed that DMF5 also appeared to bind with a different class of peptides -- one that was highly charged and easily dissolvable.","short arm of the HLA-A2 α 2 helix beginning near Val152 and continuing through His145 (Fig. The displacement is maximal at Ala150, widening the binding groove by 2 Å at this point. Overall, the MMWDRGLGMM/HLA-A2 structure confirms that the peptides in the DRG and GIG classes are not molecular mimics, differing not only in sequence, but also in conformation and in their impact on HLA-A2 structure ( Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37145988537&p=1pl&v=1&x=UjeHUDBlXhRhhu47TNBdWg
10.1073/pnas.1502549112,Biology_easy_472,"No, the new study shows.","The nutrients transported by whales, or as a consequence of whale activity, should be assimilated more rapidly, and contribute to system productivity more directly than on land.","aEURoeWe can imagine a world with relatively abundant whale populations again,aEUR he says. No, the new study shows. aEURoeFuture pastures could be set up with fewer fences and with a wider range of species,aEUR the team writes.","Such population decreases reduced the lateral distribution capacity and perhaps reduced the vertical distribution, allowing more nutrients to drop below the photic zone. The nutrients transported by whales, or as a consequence of whale activity, should be assimilated more rapidly, and contribute to system productivity more directly than on land. Also, whales and their prey may help in retaining limiting nutrients (N, P, and Fe) in the surface layer and releasing these nutrients slowly into the water (18).",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/lost-giant-poop-disrupts-whole-planet/
10.1016/j.celrep.2015.02.005,Biology_easy_473,"""We are now beginning to understand the major landmarks on that journey.""",The 3 real subclonal samples in this group of 384 were easily distinguishable from error (Supplemental Figure  S2D) Supplemental References,"Despite this, the researchers say, disease will occur in only a minority of cases. ""We are now beginning to understand the major landmarks on that journey."" Over time, this triggers a patient's symptoms, including tiredness, an increase of infections, and bruising.",We found that the 3710 VAF values (10 positions x 371 samples) at positions outside the R882 hotspot (i.e. non-targets of known leukemia-associated mutations) were always ≤0.0045 indicating a very small combined PCR-MiSeq error rate. The 3 real subclonal samples in this group of 384 were easily distinguishable from error (Supplemental Figure  S2D) Supplemental References,[1],Biology,train,1.0,news,http://www.medicaldaily.com/genetic-mutations-leukemia-present-1-every-5-middle-aged-people-few-will-develop-323624
10.1016/j.celrep.2015.06.062,Biology_easy_474,"""Overeating, which causes obesity, can be considered a food addiction, a neuropsychiatric disorder,"" Pang says.","Furthermore, no significant differences were detected in miniature inhibitory postsynaptic currents (mIPSCs) in the presence of TTX ( Figures 5I and 5J) .","[related]

Pang says why we eat, how much we eat, and when we stop eating are behaviors controlled by the central nervous system, which enables the body to respond to its environment. ""Overeating, which causes obesity, can be considered a food addiction, a neuropsychiatric disorder,"" Pang says. ""By finding out how the central nervous system regulates food intake behavior via GLP-1 signaling, we may be able to provide more targeted therapy with fewer side effects.""","In contrast, GLP-1R activation had no obvious impact on sIPSCs in non-DA neurons ( Figures 5E-5H) . Furthermore, no significant differences were detected in miniature inhibitory postsynaptic currents (mIPSCs) in the presence of TTX ( Figures 5I and 5J) . Thus, Exn4 may facilitate inhibitory synaptic transmission mediated by spontaneous action potentials in the VTA-to-NAc-projecting DA neurons.",[1],Biology,train,1.0,news,http://www.futurity.org/hormone-overeat-obesity-966452/
10.3945/jn.108.098269,Biology_easy_476,"But, in addition to applying heat, drinking peppermint tea, and taking Midol, you can help ease cramp pain by avoiding certain types of food.","Consistent with these data, high-fat feeding in mice increased TLR4 signaling in macrophages and adipocytes and impaired insulin signaling, whereas mice lacking TLR4 were resistant to these effects .","But, in addition to applying heat, drinking peppermint tea, and taking Midol, you can help ease cramp pain by avoiding certain types of food. ""Although this needs to be studied further, it's possible that following an anti-inflammatory diet could help reduce those symptoms.","SFA increased inflammatory gene expression in both cell types by TLR4/NFkB signaling . Consistent with these data, high-fat feeding in mice increased TLR4 signaling in macrophages and adipocytes and impaired insulin signaling, whereas mice lacking TLR4 were resistant to these effects . Lastly, FA-binding proteins play an important role in cross-talk between adipocytes and macrophages, as mice lacking FA-binding proteins in these tissues have reduced inflammatory signaling and improved insulin sensitivity when fed a high-fat diet .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34141204919&p=1pl&v=1&x=x6pGG9kLpRpRMMIVnDUk_Q
10.1038/s41467-018-04373-8,Biology_easy_477,"""We had the map, and knew where we were looking, and with enough digging we found the gold!""","The most significant intron-retaining transcript across VCP mu , SOD1 mu and FUS mu iPSC models was SFPQ, which encodes a protein that plays key roles in salient ALS-related pathways including RNA transcription, splicing, 3′ end processing and axon viability .","This guided the team to collectively discover that a protein called SFPQ, which normally resides inside the cell nucleus, was in fact leaving the nucleus in diseased motor neurons. ""We had the map, and knew where we were looking, and with enough digging we found the gold!"" They next confirmed that animal models of hereditary ALS also shared the same features.","These findings together raise the hypothesis that aberrant IR represents subtle manifestations of a dysregulated pathway of the developing neurons, which eventually contributes to the increased vulnerability of mature MNs. The most significant intron-retaining transcript across VCP mu , SOD1 mu and FUS mu iPSC models was SFPQ, which encodes a protein that plays key roles in salient ALS-related pathways including RNA transcription, splicing, 3′ end processing and axon viability . Subsequent experiments showed that the intron-retaining transcript is more abundant in the cytoplasm of VCP mu compared to control counterparts, and coincides with nuclear decrease of the SFPQ protein.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34143256270&p=1pl&v=1&x=4opEpx-AxefHDHwgwqlGZA
10.1038/s41467-019-09784-9,Biology_easy_479,"For men who have this aggressive form of metastatic prostate cancer and are no longer responding to chemotherapy, enzalutamide can extend survival by an average of five months.",4e) .,"The new research indicates how to block the harmful side effects of the drug, at least in mice. For men who have this aggressive form of metastatic prostate cancer and are no longer responding to chemotherapy, enzalutamide can extend survival by an average of five months. Researchers identified non-coding RNA-p21 as the main culprit for inducing neuroendocrine differentiation, saying that IncRNAp-21 can switch the function of a key gene, EZH2.","As expected, knocking down EZH2 reversed the Enz-increased STAT3 downstream genes expression, suggesting that Enz alters the EZH2 activity to modulate the STAT3 activity in C4-2 cells (Fig. 4e) . The Co-IP assay revealed that Enz treatment could enhance the interaction between EZH2 and STAT3, suggesting that Enz might increase STAT3 methylation via promoting this interaction (Fig.",[1],Biology,train,1.0,news,https://www.futurity.org/late-stage-prostate-cancer-enzalutamide-2081942-2/
10.1126/science.1245622,Biology_easy_481,"That gave neurobiologists good reason to believe that memories were not formed by new neuron production, but rather by a strengthening of the connections between existing neurons to improve the effectiveness of their communication.","S5A ), as well as sLTP (Fig.","How that relates to memory formation may be better understood with some background. That gave neurobiologists good reason to believe that memories were not formed by new neuron production, but rather by a strengthening of the connections between existing neurons to improve the effectiveness of their communication. His team's most surprising and unexpected finding, he said, was that induction of LTP in as few as three of these spines was sufficient to exert profound effects on activity of proteins that control gene transcription in the cell nucleus.","Inhibition of NMDARs with 2-amino-5-phosphonopentanoic acid (APV) (50 mM) completely prevented nuclear ERK activation ( Fig. S5A ), as well as sLTP (Fig. In contrast, blockade of VSCCs with CdCl 2 (200 mM) did not prevent nuclear ERK activation (Fig.",[1],Biology,train,1.0,news,http://www.technology.org/2013/12/07/research-advances-knowledge-triggers-memory-formation/
10.1186/1741-7007-5-7,Biology_easy_482,"Yes, they can survive, but fortunately, itas fairly easy to get rid of them once they end up there.","When the same ML analysis was performed enforcing a molecular clock, the resulting tree topology did not change and the resulting tree score was not significantly different than the unconstrained score (p = 0.7625).","But outside of those hearty gorilla pubic lice than managed to infect ancient humans and give rise to our own unique species of pubic lice, crabs really donat fare well off of the host. Yes, they can survive, but fortunately, itas fairly easy to get rid of them once they end up there. Leone recommends washing sheets, towels or clothing in hot water with detergent, which should finish them off for good.","Maximum likelihood (ML) analysis of the combined Cox1 and EF-1α dataset (as well as individual gene datasets) from lice produced a single, well-supported phylogeny in agreement with results from previous analyses ( Figure 3 ; ). When the same ML analysis was performed enforcing a molecular clock, the resulting tree topology did not change and the resulting tree score was not significantly different than the unconstrained score (p = 0.7625). The ML analysis of the host Cox1 data also resulted in a single phylogeny in agreement with known relationships among these primate taxa ( Figure 3 ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38367278255&p=1pl&v=1&x=yswtcJ-vDILUx8q7FnTbFQ
10.1038/s41596-018-0072-z,Biology_easy_483,"By shortening breeding cycles, the method allows scientists and plant breeders to fast-track genetic improvements such as yield gain, disease resistance and climate resilience in a range of crops such as wheat, barley, oilseed rape and pea.",B072M7P7QJ) • LED-supplemented glasshouse setup c CRITICAL This section provides an overview of the equipment required for setting up SB in a glasshouse using LED lamps for supplementary lighting.,"It speeds up the breeding cycle of plants: for example, six generations of wheat can be grown per year, compared to two generations using traditional breeding methods. By shortening breeding cycles, the method allows scientists and plant breeders to fast-track genetic improvements such as yield gain, disease resistance and climate resilience in a range of crops such as wheat, barley, oilseed rape and pea. Being able to do this in a compact desktop chamber enables affordable, cutting-edge research on a range of crops to take place before the experiments are scaled up to larger glass houses.","To construct your low-cost growth cabinet, the components listed below are required. B072M7P7QJ) • LED-supplemented glasshouse setup c CRITICAL This section provides an overview of the equipment required for setting up SB in a glasshouse using LED lamps for supplementary lighting. Its efficacy is demonstrated for a range of crop species, along with some examples of how single-seed descent for wheat and barley can be carried out.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37739353265&p=1pl&v=1&x=t8Mkb8UU1ZA1-y1v_j0Fvw
10.1073/pnas.1401006111,Biology_easy_484,"Although rates of MRSA infections have dropped by about 50 percent in hospital settings, their spread elsewhere will continue to be a concern, along with the hundreds of other superbugs.",Their distribution closely mirrored the phylogeny of the core genome ( Fig.,"That's because they were also able to find reservoirs of MRSA in-between affected households, completing a network of transmission. ""We have to attempt to remove the colonization from the home."" Although rates of MRSA infections have dropped by about 50 percent in hospital settings, their spread elsewhere will continue to be a concern, along with the hundreds of other superbugs.","However, the genetic basis for this requires further investigations. Their distribution closely mirrored the phylogeny of the core genome ( Fig. 5 and Fig.",[1],Biology,train,1.0,news,http://www.medicaldaily.com/mrsa-superbug-turns-american-homes-reservoirs-highlighting-bacterias-easy-spread-through-communities
10.1038/s41558-018-0224-8,Biology_easy_485,"Prof Rod Wilson from the University of Exeter also commented on the plight for fish in a higher CO 2 future world: ""Our intriguing results show that CO 2 impacts the nose of the fish directly.","Under elevated CO 2 the responses to l-alanine, l-arginine, l-glutamate, cyprinol sulfate, scymnol sulfate and alarm cue were up to 46% lower than those of controls (n = 6-11 fish per odorant per treatment, P = 0.027, P = 0.040, P = 0.028, P = 0.011, P = 0.012 and P = 0.018, respectively; Fig.","Dr Porteus said: ""I wanted to examine if fish had any ability to compensate for this reduced sense of smell, but found that instead of increasing the expression of genes for smell receptors in their nose they did the opposite, exacerbating the problem."" Prof Rod Wilson from the University of Exeter also commented on the plight for fish in a higher CO 2 future world: ""Our intriguing results show that CO 2 impacts the nose of the fish directly. This will be in addition to the impact of CO 2 on their central nervous system function suggested by others previously, which proposed an impaired processing of information in the brain itself.","3) , but had no effect on the remainder (that is, elevated CO 2 did not increase the amplitude or sensitivity of the response to any of these odorants). Under elevated CO 2 the responses to l-alanine, l-arginine, l-glutamate, cyprinol sulfate, scymnol sulfate and alarm cue were up to 46% lower than those of controls (n = 6-11 fish per odorant per treatment, P = 0.027, P = 0.040, P = 0.028, P = 0.011, P = 0.012 and P = 0.018, respectively; Fig. The thresholds of detection for l-cysteine (P = 0.049), l-alanine (P = 0.029) and l-glutamate (P = 0.0047), and conspecific bile (P = 0.029) were two-to fivefold higher under elevated CO 2 (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34614398292&p=1pl&v=1&x=hAj7yFxN6bnZNkm03LxG1g
10.1016/j.celrep.2014.12.007,Biology_easy_486,"""Our studies were conducted in mice, but the greater implication of the work relates to the fact that circadian disruption is very common in modern society, and one consequence of such disruption could be abnormal function of stem cells and accelerated aging,"" he said.","Conversely, in Bmal1 mutant mice, which show no temporal separation of glycolytic and oxidative metabolism, this protection is presumably lost, leading to increased DNA damage.","The Andersen-Gratton study also revealed that the circadian clock within stem cells shifts the timing of cell division such that the stages of the cell division cycle that are most sensitive to DNA damage are avoided during times of maximum oxidative phosphorylation. ""Our studies were conducted in mice, but the greater implication of the work relates to the fact that circadian disruption is very common in modern society, and one consequence of such disruption could be abnormal function of stem cells and accelerated aging,"" he said. Andersen adds that it is possible that future studies could advance therapeutic insights from this research.","Our findings suggest that the circadian clock confers time-of-day-dependent shifts in glycolysis versus oxidative phosphorylation within proliferating epithelial stem cells, thus minimizing DNA damage during S phase. Conversely, in Bmal1 mutant mice, which show no temporal separation of glycolytic and oxidative metabolism, this protection is presumably lost, leading to increased DNA damage. For example, in Figure S1C , the edge of the dermis is identified at a depth of 18 mm, corresponding to the last Z section of the dermis that contains collagen.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/01/150106154607.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41467-018-04746-z,Biology_easy_488,"""It puts us closer to commercialization,"" said Zhifeng Ren, M.D.",We measured a very small Tafel slope of 22.7 mV dec −1 in the low overpotential ranges 33 (Fig.,"Lower energy requirements means the hydrogen could be produced at a lower cost. ""It puts us closer to commercialization,"" said Zhifeng Ren, M.D. ""In contrast, our materials are based on earth abundant elements and exhibit comparable performance with those of platinum group materials,"" she said.","Indeed this overpotential of 154 mV in alkaline conditions is among the lowest for catalyzing OER thus far (Supplementary Table 2 ), even surpassing the presently most active NiFe LDH (double layered hydroxide) catalyst (~200 mV) 1 32 . We measured a very small Tafel slope of 22.7 mV dec −1 in the low overpotential ranges 33 (Fig. 2c , Supplementary Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34427937490&p=1pl&v=1&x=RIP9pqshLOQFw8Iaxdjs6w
10.1038/nm.4184,Biology_easy_490,Their search landed them on three drugs.,1105,"Their search landed them on three drugs. PHA-690509 is still under investigation and is being used on cancer patients, while emricasan is still being tested to determine if it can help reduce liver damage in patients with Hepatitis C.

""It takes years, if not decades, to develop a new drug,"" said Hongjun Song of Johns Hopkins, who worked on the project, in a report from NBC News. Potential treatments for Ebola and Hepatitis C were also discovered using such methods.","Taken together, these results indicate that niclosamide and PHA-690509 inhibit ZIKV infection at a post-entry stage, probably at the viral RNA replication step. 1105 Our efforts so far have led to the identification of small molecules that either protect against cell death in multiple neural cell types or suppress ZIKV replication.",[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/27747/20160830/zika-cure-update-drugs-used-treat-cancer-hepatitis-c-shows.htm
10.1038/s41593-018-0262-6,Biology_easy_491,I think you've got to try the impossible to make the possible possible.,"As observed in rats, high-frequency bursts of EES required markedly reduced stimulation amplitudes to elicit a motor response, compared to single pulses (Fig.","I'm surprised at what we have been able to do. I think you've got to try the impossible to make the possible possible. It's a lot of fun -- it feels really good,"" he told the BBC.","This feature allowed us to evaluate the concept of high-frequency EES in humans. As observed in rats, high-frequency bursts of EES required markedly reduced stimulation amplitudes to elicit a motor response, compared to single pulses (Fig. 8e,f) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37559012880&p=1pl&v=1&x=oRkdPsA1PE01uPlI3tNyfQ
10.1038/s41598-018-30033-4,Biology_easy_493,Shead also be the stateas first out gay congresswoman.,KEGG metabolic pathway analysis provided additional information on possible function showing the pathways that the DE transcripts from the set of 507 transcripts and 160 transcripts identified in comparisons between top and bottom tissues for high and low fiber groups take part in.,"Itas got all the news you need to start your day. Sharice Davids/Flickr

If Sharice Davids wins, shead become the first Native American to represent the state of Kansas in Congress. Shead also be the stateas first out gay congresswoman.","S2 in Additional file 3) suggested that a large proportions of the DE transcripts were attributed to bins 29 (protein), 27 (RNA/transcription factors), 20 (stress), 34 (transport), 16 (secondary metabolism), 31 (cell), 33 (development), 26 (miscellaneous enzyme families), 21 (reduction-oxidation regulation), 30 (signaling), 10 (cell-wall) and 13 (amino acid metabolism). KEGG metabolic pathway analysis provided additional information on possible function showing the pathways that the DE transcripts from the set of 507 transcripts and 160 transcripts identified in comparisons between top and bottom tissues for high and low fiber groups take part in. The results showed that the largest functional pathway was the phenylpropanoid biosynthesis (related to the synthesis of lignin monomers and flavonoid biosynthesis) followed by phenylalanine metabolic pathway, representing 8.28% and 4.9%, respectively, in the DE transcripts of the high-fiber T-B comparison.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34752361647&p=1pl&v=1&x=dJyQYAjELlF4bQZi6fApZw
10.1016/j.celrep.2019.02.032,Biology_easy_494,"""I especially like the dandelion analogy.",ALDH1Ai-driven necroptosis is dependent on active transcription and translation.,"""You can think of stem-like cells as seeds. ""I especially like the dandelion analogy. All it takes is 11 stem-like cancer cells to form a tumor, Buckanovich said.","Our study, thus, links ALDH activity and necroptosis. ALDH1Ai-driven necroptosis is dependent on active transcription and translation. ALDH1Ai induced high levels of UCP1 and UCP3 mRNA preferentially in CD133 + cells.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38745190449&p=1pl&v=1&x=royVQ2M_Lp_mNGeTETMuBA
10.1016/j.yfrne.2014.04.004,Biology_easy_495,"Men were also more likely to have lung disease, vasculitis, lymphoma, and had higher levels of the antibodies that were causing issues with tissues aA even though both women and men had the same levels of dry eye and mouth.",3.3.2.2.,"Menopause also seems to affect lupus symptoms in women, reducing the frequency of symptom flares while also potentially increasing organ damage. Men were also more likely to have lung disease, vasculitis, lymphoma, and had higher levels of the antibodies that were causing issues with tissues aA even though both women and men had the same levels of dry eye and mouth. They're also more likely than men to have enthesitis, or inflammation of the tendons at the point where they meet bones.","Thus, elevated levels of cpn 10 may contribute to the beneficial effects of pregnancy on autoimmune disease. 3.3.2.2. For CD, the activity of disease was significantly lower during pregnancy as determined by the Harvey-Bradshaw index .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39469084890&p=1pl&v=1&x=OdyyPcMkSeiewBR_8oaCpQ
10.1098/rstb.2015.0168,Biology_easy_497,"""That intersection is very complex, and even more difficult to predict.",Temperature-specific palaeoclimate reconstructions relevant to the south-west do show the early decades of the 1600s had relatively cool summers during this period of infrequent widespread fires in the Jemez Mountains.,"The implications of that will play out for millennia. ""That intersection is very complex, and even more difficult to predict. When I say there's no new normal, I mean it.","Although the SEA results support an interpretation of human interference with interannual climate-fire associations before 1680 CE, it is possible that longer-term climate patterns could have played some role in changing fire patterns. Temperature-specific palaeoclimate reconstructions relevant to the south-west do show the early decades of the 1600s had relatively cool summers during this period of infrequent widespread fires in the Jemez Mountains. However, decade to multi-decade temperature and fire trends in our rstb.royalsocietypublishing.org Phil.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34691890363&p=1pl&v=1&x=YDwpPpQ3it3kQAm23jznyw
10.1016/j.celrep.2018.09.028,Biology_easy_499,"They're healthy, just not on.","In contrast, changes in the distribution of postsynaptic receptors can be detected within 5-10 min after HFS, consistent with the time course observed following exogenous application of netrin-1.","""We've identified a huge target for drugs,"" says Kennedy. They're healthy, just not on. Perhaps there is a reservoir of synapses that can be used to change the strength of connections between neurons.","Short-term facilitation of synaptic responses following HFS is mediated through changes in presynaptic Ca 2+ that enhance transmitter exocytosis . In contrast, changes in the distribution of postsynaptic receptors can be detected within 5-10 min after HFS, consistent with the time course observed following exogenous application of netrin-1. Moreover, our findings indicate that following LTP-inducing stimulation, the NMDAR-mediated Ca 2+ influx mobilizes the secretion of netrin-1 from dendrites at or near synaptic sites (Figure 1 ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37610087807&p=1pl&v=1&x=5c_zMpT9ApvKzoscOW0uGw
10.1038/s41467-018-05268-4,Biology_easy_501,"But the Ames Laboratory research group found that a rare earth compound made of Europium and Indium, Eu2In, displayed a startlingly sharp magnetic phase transition accompanied with a giant magnetocaloric effect (change in temperature) and no hysteresis.","Above the Curie temperature, the metamagnetic jumps observed in the isothermal measurements indicate nearly fully reversible magnetic field-induced PM↔FM transitions with a nearly negligible (≤0.1 T) magnetic hysteresis, in line with the extremely narrow thermal hysteresis.","The mechanism of the material's changing magnetic state is so unusual, it provides new possibilities for discovery of similar materials. But the Ames Laboratory research group found that a rare earth compound made of Europium and Indium, Eu2In, displayed a startlingly sharp magnetic phase transition accompanied with a giant magnetocaloric effect (change in temperature) and no hysteresis. ""This was a very surprising result and one of the least expected places to find such a phenomenon,"" said Yaroslav Mudryk, an Ames Laboratory scientist.","−1 , in line with a fully collinear ferromagnetism, the divalent character of Eu (gJ = 7 μ B , where g is gyromagnetic ratio and J = S = total angular momentum quantum number of Eu 2+ ), and a small but measurable additional magnetic contribution from the 5d states of Eu, even though theoretically, Eu 2+ is expected to have a [Xe] 4f 7 6s 2 5d 0 configuration. Above the Curie temperature, the metamagnetic jumps observed in the isothermal measurements indicate nearly fully reversible magnetic field-induced PM↔FM transitions with a nearly negligible (≤0.1 T) magnetic hysteresis, in line with the extremely narrow thermal hysteresis. Both sets of data are in good agreement, leading to ∂T C /∂B ≈ +3.5 K T −1 , which is in line with T C = 55 K determined from AC measurements in 0.0005 T AC field (Supplementary Note 3) and T C = 58 K determined from the 1 T data presented in Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34729478492&p=1pl&v=1&x=XoWM1MMzRiaH4CFgCBYmKg
10.1126/sciadv.aap7885,Biology_easy_502,"""A scientist using virtual screening is like a customer ordering in a restaurant.","In the maximization regime, the mean of the melting temperature was increased by 20 °C to 200 °C.","ReLeASE has the unique ability to create and evaluate new molecules. ""A scientist using virtual screening is like a customer ordering in a restaurant. ""The ability of the algorithm to design new, and therefore immediately patentable, chemical entities with specific biological activities and optimal safety profiles should be highly attractive to an industry that is constantly searching for new approaches to shorten the time it takes to bring a new drug candidate to clinical trials,"" said Tropsha.","Clearly, this property minimization strategy was extremely effective, as it allowed for the discovery of molecules in the regions of the chemical space far beyond those of the training set of drug-like compounds. In the maximization regime, the mean of the melting temperature was increased by 20 °C to 200 °C. As expected, the generated library indeed included substantially more complex molecules with the abundance of sulphur-containing heterocycles, phosphates, and conjugated double bond moieties.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34698039737&p=1pl&v=1&x=RKZEUvbzaCKGbk1NjWE6uw
10.1111/oik.03196,Biology_easy_503,"Additionally, any steps people can take to minimize their impact on climate, Schachat advises, can help a that can be burning less fossil fuel, eating less meat, and being a responsible tourist when you enter a habitat.",Monarch populations in Spring South significantly predict those in the Midwest.,"Schachat emphasizes that, because butterflies pollinate plants, a world in which they go extinct means repercussions for the plants they pollinate and the myriad creatures that eat those plants. aThe loss of any plants that rely on butterflies will throw the entire plant community out of balance,a Schachat says, awhich will have repercussions throughout the ecosystem.a

As for what can be done, Agrawal advises people who care about the problem to become involved in habitat conservation and restoration a anything from donating to conservation organizations to working to keep lands wild and free from development. Additionally, any steps people can take to minimize their impact on climate, Schachat advises, can help a that can be burning less fossil fuel, eating less meat, and being a responsible tourist when you enter a habitat.","2 Spring South to Midwest Forward selection, Backward selection, and AIC all lead to Model 3, Midwest ⇠ Spring South with the donor region as the only significant predictor (p<0.05). Monarch populations in Spring South significantly predict those in the Midwest. There is no evidence for a temporal trend in this relationship.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38200136600&p=1pl&v=1&x=mgg1CcxKPjlMj-CQmiNAHw
10.1086/696124,Biology_easy_504,But other factors may also come into play.,Arthropods that carried D. muscipula pollen included 64 taxa (61 of which were identified to our target taxonomic resolution).,"""The pollinator species may simply be staying above the danger zone as they go from flower to flower, making them less likely to be eaten."" But other factors may also come into play. ""We know that the snap traps are different colors than the flowers, and may possibly lure different species,"" Professor Sorenson said.","Overall, 69% of individual flower visitors carried pollen (D. muscipula and/or heterospecific pollen), but only 56% carried D. muscipula pollen; of these, 25% bore pure D. muscipula loads while 75% bore a mixture of D. muscipula and other pollen. Arthropods that carried D. muscipula pollen included 64 taxa (61 of which were identified to our target taxonomic resolution). Hymenoptera (principally bees) and Coleoptera were the most abundant orders on flowers and were the most likely to carry D. muscipula pollen ( fig.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/1RjoZKm711w/venus-flytraps-pollinators-05701.html
10.1186/1471-2180-14-189,Biology_easy_508,"Get enough sleep

Getting enough sleep not only improves your mood and cognitive behavior, but it also improves gut health.","Additional analysis of the Shannon, equitability and Chao1 alpha diversity metrics showed no statistical difference between the two groups ( Figure 1A -C).","Exercising regularly and sleeping well also helps in reducing stress levels. Get enough sleep

Getting enough sleep not only improves your mood and cognitive behavior, but it also improves gut health. Eating more vegetables improves gut health as a vegetarian diet contains high levels of prebiotic fiber.","After normalization of the datasets by rarefaction, we observed no statistical difference in the total number of operational taxonomic units (OTU) between the SDR and control mice (data not shown). Additional analysis of the Shannon, equitability and Chao1 alpha diversity metrics showed no statistical difference between the two groups ( Figure 1A -C). Thus, a single two-hour cycle of exposure to the social stressor did not affect the alpha diversity of the mucosa-associated microbiota.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39337495793&p=1pl&v=1&x=VKCL6R2kmkDFDwaubqSi0w
10.1098/rspb.2016.0615,Biology_easy_509,"Santana hopes their conclusions will inform ecological studies of carnivorous bats, which by and large reside in tropical and sub-tropical environments around the globe.","This is illustrated by the relatively lower coronoid process in the mandible, which would cause stretching and lower contractile forces in the temporalis muscle at extreme gapes .","She and Cheung found that the skulls of carnivorous bats emphasized a strong bite force at the expense of gape width when compared to other mammalian carnivores, perhaps indicating that some of the key trade-offs in feeding and chewing strategies enabled these bats to subsist on a vertebrate-rich diet. Santana hopes their conclusions will inform ecological studies of carnivorous bats, which by and large reside in tropical and sub-tropical environments around the globe. In addition, Santana says this study demonstrates how ecological factors like diet can so heavily depend on the adaptive changes that evolution provides.","From a purely functional perspective, we expect that carnivorous bats would be less suited for wide gapes than the most specialized carnivoran predators, felids. This is illustrated by the relatively lower coronoid process in the mandible, which would cause stretching and lower contractile forces in the temporalis muscle at extreme gapes . When compared rspb.royalsocietypublishing.org Proc.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/ulbQpNHfqR8/
10.1126/science.1210558,Biology_easy_510,"And unlike the Grinch, they're still happy to do their dirty work, no matter how big their hearts get.","As in mammals, cardiac growth in the python appeared to be hypertrophic rather than hyperplastic, as there was no sign of 5-bromo-2´-deoxyuridine (BrdU) incorporation in the postprandial heart (Fig.","The swelling Leinwand observed may occur only under a certain range of conditions, he says. ""Pythons can digest very large meals and can have very large metabolic changes without necessarily having the growth in heart size."" And unlike the Grinch, they're still happy to do their dirty work, no matter how big their hearts get.","S1A ), with a maximum increase seen at 3 days post-feeding (dpf ) ( fig. As in mammals, cardiac growth in the python appeared to be hypertrophic rather than hyperplastic, as there was no sign of 5-bromo-2´-deoxyuridine (BrdU) incorporation in the postprandial heart (Fig. Although the cellular architecture of the python ventricle did not allow for reliable quantification of myocyte size ( fig.",[1],Biology,train,1.0,news,http://news.sciencemag.org/2011/10/incredibly-expanding-snake-heart
10.1016/j.arr.2018.11.003,Biology_easy_514,Brief company video: https:/ / www.,Experiments showed that the model is able to achieve a mean absolute error of 2.3 years within the age range of 20 to 80 years old.,"""We are happy to present our latest research at the Pionners'19, which gathers the leading longevity leaders. Pioneers '19 is the ultimate meeting point for 2500 bold, pioneering entrepreneurs to look into the future and beyond. Brief company video: https:/ / www.",The algorithm developed in this study could also be used as a biomarker for neurodevelopment and disease detection that can be easily translatable to the bedside. Experiments showed that the model is able to achieve a mean absolute error of 2.3 years within the age range of 20 to 80 years old. Those results suggest that high-resolution images of eye corner wrinkles can be utilized to obtain accurate chronological age estimation.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39084328276&p=1pl&v=1&x=2zWSA1gVWkR23iGvY22gXA
10.1073/pnas.1807709115,Biology_easy_515,"""This certainly was not the only thing that was going on,"" Goldenfeld said.","A positive signal was detected in 3 of 80 screened colonies, and was verified via sequencing (SI Appendix, Fig.","This research proves that it played a part, billions of years ago, in eukaryotes becoming the advanced organisms we know today. ""This certainly was not the only thing that was going on,"" Goldenfeld said. ""But if it hadn't happened, it's hard to see how you could have complex life.""","4A) show that cells no longer carrying pTKIP-EL1H still contain EL1H, demonstrating successful chromosomal integration. A positive signal was detected in 3 of 80 screened colonies, and was verified via sequencing (SI Appendix, Fig. 4B) to report EL1H integration via fluorescence.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37739665152&p=1pl&v=1&x=HF7KVZsgM1lNK0hn2Vg7oA
10.1073/pnas.1507055113,Biology_easy_516,"The eruption ""spewed out a lot of ash that completely blanketed the landscape.""","In the farthest southeastern (FLK S ) trenches, high C/V values and high δ 13 C values for C lignin phenols (Fig.","But based on the high concentration of bones, the primates probably obtained carcasses elsewhere and ate the meat in the woods for safety. The eruption ""spewed out a lot of ash that completely blanketed the landscape."" The hominins may have killed the animals for their meat or scavenged leftover meat.","3 and 4A ) collectively indicate dense woody cover (Fig. In the farthest southeastern (FLK S ) trenches, high C/V values and high δ 13 C values for C lignin phenols (Fig. Biomarkers define a heterogeneous landscape at Olduvai and suggest an influence of local resources on hominin diets and behavior.",[1],Biology,train,1.0,news,http://www.science20.com/news_articles/early_human_habitat_in_tanzaia_recreated_shows_life_was_no_harmony_with_nature_picnic-167726
10.1073/pnas.1613337113,Biology_easy_517,"This work gives us a very important clue about where we should look if we want to sort this out.""","With new mouse models and tissue expansion to allow nanoscale imaging, we demonstrate that striatonigral fibers originating in striosomes form bouquet-like arborizations innervating clusters of dopamine-containing neurons and their ventrally extending, tightly bundled dendrites.","Hard decisions

This finding expands the known decision-making circuit so that it encompasses the prefrontal cortex, striosomes, and a subset of dopamine-producing cells. Together, the striosomes may be acting as a gatekeeper that absorbs sensory and emotional information coming from the cortex and integrates it to produce a decision on how to react, which is initiated by the dopamine-producing cells, the researchers say. This work gives us a very important clue about where we should look if we want to sort this out.""","In the striosome lines P172-mCitrine and Sepw1-Cre NP67 with the Ai14 reporter (9), the proportion of striosomal fibers to With new mouse models and tissue expansion to allow nanoscale imaging, we demonstrate that striatonigral fibers originating in striosomes form bouquet-like arborizations innervating clusters of dopamine-containing neurons and their ventrally extending, tightly bundled dendrites. The stunning selectivity of striosomal output to the bouquets suggests that the bouquets could exert powerful and focused control over elements of the dopamine system in normal and abnormal states.",[1],Biology,train,1.0,news,http://news.mit.edu/2016/neural-connections-linked-emotional-decision-making-0919
10.1101/gr.171934.113,Biology_easy_518,"Within 48 hours, doctors had their answer: Joshua had a lethal form of bacteria called Leptospira.","In particular, the speed and throughput of the pipeline make it highly convenient and cost-effective when run on a cloud server (Supplemental Table S1 ).","Within 48 hours, doctors had their answer: Joshua had a lethal form of bacteria called Leptospira. And while it's lethal, it's also treatable. Heavy doses of penicillin did the trick.","To our knowledge, SURPI is the only NGS pipeline for pathogen identification to be extensively tested across multiple clinical sample types representing a variety of infectious diseases (Figs. In particular, the speed and throughput of the pipeline make it highly convenient and cost-effective when run on a cloud server (Supplemental Table S1 ). SURPI analysis is also being incorporated as part of an ongoing effort to validate unbiased NGS assays for pathogen diagnosis in a CLIA (Clinical Laboratory Improvement Amendments)-certified laboratory.",[1],Biology,train,1.0,news,http://www.newser.com/story/187947/breakthrough-dna-test-saves-boy-in-48-hours.html
10.1038/s41467-017-02041-x,Biology_easy_519,"""It's like the ground has shifted under your feet.","6b) can become singly coordinated, with its depopulated O 2p states raised by several eV into the TM redox band.","""There was a weird reordering of what elements are involved in the battery's function,"" he said. ""It's like the ground has shifted under your feet. This was a big puzzle.""","While our treatment here is by no means exhaustive, we find that TM migration in all cases results in a shift to higher energy of the O pDOS regardless of the pathway examined and the identity of the migrating TM, suggesting that this observation is general and largely independent of the migration mechanism. 6b) can become singly coordinated, with its depopulated O 2p states raised by several eV into the TM redox band. K-edge XAS ( Supplementary Fig.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/kJcua8gW9bk/
10.1126/sciadv.aat0098,Biology_easy_520,"When cut into pieces, it can quickly mend itself upon reattachment.","S5D , orange and blue curves); however, when the pushing speed was increased, the resistance could not recover its initial value because of the formation of residual deformation ( fig.","As well as being able to stretch by more than 3400 percent, the material can quickly return to its original form and will adhere to many surfaces, including skin. When cut into pieces, it can quickly mend itself upon reattachment. The materials differing sensitivity to stretching and compression is a breakthrough discovery that adds a new dimension to the sensing capability of hydrogels, says first author, Yizhou Zhang, a postdoc in Alshareef's lab.","At low speed, the deformation could be fully recovered ( fig. S5D , orange and blue curves); however, when the pushing speed was increased, the resistance could not recover its initial value because of the formation of residual deformation ( fig. However, when combined with the anisotropic response to compressive and tensile strains, it is possible to observe interesting sensing capabilities using the M-hydrogel.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34439214663&p=1pl&v=1&x=vJXsRlCV9DPPWwAlIu-C3g
10.1038/nature19792,Biology_easy_521,"The virtual 300,000-year-old fossil has relatively modern features: its round cranium, relatively high forehead, and slight brow ridges and facial projection make it similar in morphology to some fossils that are only 100,000 years old.","We note that while this makes a single component a reasonable fit to the data, as K increases the specific choice becomes less important.","(3) This relationship allowed the researchers to calculate the likely skull dimensions of the most recent ancestor of all Homo sapiens groups. The virtual 300,000-year-old fossil has relatively modern features: its round cranium, relatively high forehead, and slight brow ridges and facial projection make it similar in morphology to some fossils that are only 100,000 years old. Their analysis suggests our species arose through the hybridization of populations from South and East Africa.","Additionally, the data are left-censored since we cannot reliably detect haplotypes that are very short. We note that while this makes a single component a reasonable fit to the data, as K increases the specific choice becomes less important. ∈ .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=40159107214&p=1pl&v=1&x=BoCHbTB3JXRkZa9ui6WBhg
10.1038/s41467-019-09935-y,Biology_easy_522,"""They highlight this as a much more highly interactive system than we've understood previously.""",Total gravimetric LAI measured at the San Juan region sites was attributed solely to atmospheric dust deposition on snow.,"""I want to say that this is a really important, groundbreaking paper, because it shows us for the first time snowpack feeding back to fire regimes in a very direct, mechanistic way,"" said wildfire expert Donald Falk of the University of Arizona, who commented on the new research for E&E News. ""They highlight this as a much more highly interactive system than we've understood previously."" In future research, it may be useful to collect snow samples from a wider variety of landscapes across the Western states, to be sure the same effects hold true throughout the region, Falk noted.",Inorganic debris concentrations measured in the chronosequence samples from the southern Rockies were similar to low-dust-year concentrations measured in subalpine snowpacks in the San Juan region of the Rocky Mountains 38 . Total gravimetric LAI measured at the San Juan region sites was attributed solely to atmospheric dust deposition on snow. Both SNICARmodeled and measured albedo were lowest during the first year following fire and increased during the 15-year chronosequence ( Fig.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39192736914&p=1pl&v=1&x=UZjvGNxeAkclqCjqOrMAuA
10.1016/j.cmet.2017.08.006,Biology_easy_523,"When grandpa nudges the settings on the thermostat, there's likely a good reason.","HNF4α binding peaks were observed in proximity to promoters of PPARα, Cpt1b, Octn2, and CrAT ( Figure 5F ).","When grandpa nudges the settings on the thermostat, there's likely a good reason. After treatment, they tolerate chilly conditions that would ordinarily trigger hypothermia. ""We uncovered a well-controlled process for mobilizing energy to the tissues that need it,"" explains senior author Claudio Villanueva, assistant professor of biochemistry at U of U Health.","Although Cpt1 and Cpt2 regulation by HNF4α is well established, we also observed reduction in Octn2 and CrAT expression in the livers of hepatocyte-selective HNF4α null mice . HNF4α binding peaks were observed in proximity to promoters of PPARα, Cpt1b, Octn2, and CrAT ( Figure 5F ). Together these findings suggest that hepatic HNF4α is a major regulator of the cold adaptive response in the liver.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/BOFu4Yo9P10/
10.1038/ncomms7310,Biology_easy_524,These would be important for example for environmental monitoring for measuring air-pollution or in medical diagnostics as a cheap tool to do breath analysis.,Silicon nanophotonic wire waveguides can be engineered 17 within a nanometre precision in a standard CMOS facility.,The results are an important step towards a small-footprint chip scale mid-infrared frequency comb source. Such sources could act as sensitive cheap gas sensors in the mid-infrared. These would be important for example for environmental monitoring for measuring air-pollution or in medical diagnostics as a cheap tool to do breath analysis.,"This aberration increases the conversion of parasitic processes significantly 12 and makes modelling difficult. Silicon nanophotonic wire waveguides can be engineered 17 within a nanometre precision in a standard CMOS facility. Such waveguides offer many advantages for mid-infrared nonlinear optics, mostly related to the wide transparency range of silicon (1.1-8 mm), its high nonlinear refractive index, the possibility of precise dispersion engineering of the waveguide platforms and the high refractive index contrast between the silicon waveguide core and the cladding material (typically, SiO 2 or air), which allows for densely integrated waveguide systems with a nonlinear parameter one to two orders of magnitude higher than that possible in the chalcogenide or silicon nitride systems.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150310123204.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1098/rspb.2014.0970,Biology_easy_525,Kawahara said the yearlong study is one of the first to utilize a massive amount of genetic data to answer questions about the history of butterflies and moths.,com/stamatak/ExaML) for amino acids.,"""This is an important time in the history of science when we can use DNA sequencing on a very large scale."" Kawahara said the yearlong study is one of the first to utilize a massive amount of genetic data to answer questions about the history of butterflies and moths. The analysis reveals monumental discoveries about the lineage of Lepidoptera, including strongly contradicting the traditional placement of butterflies in evolutionary history, Kawahara said.",The 26 taxa represented each major lineage in figure 2. com/stamatak/ExaML) for amino acids. Initial attempts to determine the best partitioning scheme by gene and codon position in PARTITIONFINDER did not complete in a reasonable amount of time.,[1],Biology,train,1.0,news,http://www.technology.org/2014/08/01/new-study-advances-dna-revolution-tells-butterflies-evolutionary-history/
10.1038/s41467-018-06041-3,Biology_easy_526,"They found that Staufen1 binds Ataxin2, a protein that is both responsible for ataxia and a risk factor for ALS.","The strength of protein-protein interaction did not differ for wild-type and mutant ATXN2, and we found co-localization of STAU1 with ATXN2 aggregates in individuals with SCA2 and in an SCA2 mouse model (Fig.","These results suggest that targeting Staufen1 could have therapeutic potential in people. They found that Staufen1 binds Ataxin2, a protein that is both responsible for ataxia and a risk factor for ALS. A role for Staufen1 in disease pathology became evident upon genetically depleting it from mice with an ataxia-like condition.","Here, we show for the first time that STAU1 is a novel RNAdependent interactor for ATXN2 (Fig. The strength of protein-protein interaction did not differ for wild-type and mutant ATXN2, and we found co-localization of STAU1 with ATXN2 aggregates in individuals with SCA2 and in an SCA2 mouse model (Fig. We showed increased STAU1 levels in SCA2-FBs and LBCs, SCA2 mouse cerebellar extracts, and in ALS cells expressing mutant TDP-43 (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37035947700&p=1pl&v=1&x=_fBNSBfaccKApqo0JC8KpA
10.1038/s41467-019-09113-0,Biology_easy_527,Much of this data became available only over the last 10 or so years.,"Given the unlikelihood of >80-90% crystallization producing the erupted compositions in nature, we also calculate a more realistic scenario in which magmas are produced by a mixture of the two end member processes with 60% of crystallization and the remainder through crustal melting.","The oceanic plate is full of water, lowering the melting point of the mantle as the plate slides deeper into the Earth. Much of this data became available only over the last 10 or so years. ""That's the big new finding,"" Till explained.","The volume and composition of material erupted at Newberry and Three Sisters region (latitudes 43.5-44.5°N) requires a different balance between crystallization and crustal melting, as 60% crystallization does not release enough heat to produce the remainder of magmas through crustal melting. Given the unlikelihood of >80-90% crystallization producing the erupted compositions in nature, we also calculate a more realistic scenario in which magmas are produced by a mixture of the two end member processes with 60% of crystallization and the remainder through crustal melting. The results along the Cascades volcanic arc are constrained as part of an inversion over the broader Cascadia region.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38871624173&p=1pl&v=1&x=NOJVqjqEy3OLIt_IiBNtcg
10.1093/jmammal/gyu013,Biology_easy_528,"""The gelada case is comparable to what early domestication of dogs might have been like,"" study researcher Claudio Sillero, of the University of Oxford, told New Scientist's Bob Holmes.","Rainfall averaged 1,650 ± 243 mm per year and was strongly seasonal, and more than half of annual rainfall occurred during July and August .","This peaceful interaction could be similar to how dogs were first domesticated by humans. ""The gelada case is comparable to what early domestication of dogs might have been like,"" study researcher Claudio Sillero, of the University of Oxford, told New Scientist's Bob Holmes. From their observations, they think the mutual friendship helps the wolves hunt, by making rodents easier to spot and catch.","From 2007 to 2012, the average monthly temperature (± SD) at Guassa was 11.0 ± 1.2°C . Rainfall averaged 1,650 ± 243 mm per year and was strongly seasonal, and more than half of annual rainfall occurred during July and August . During this period, geladas encountered Ethiopian wolves often, feral dogs occasionally, and servals rarely, and did not encounter cryptic African wolves, hyenas, or leopards.",[1],Biology,train,1.0,news,http://www.businessinsider.com/are-these-monkeys-domesticating-wolves-2015-6
10.1016/j.clnu.2012.11.018,Biology_easy_529,La variante mas popular implica 16 horas de ayuno y ocho horas en las que puedes comer.,The anabolic response can only be determined when synthesis and breakdown are measured simultaneously.,"El ayuno intermitente es cuando comes todas las calorias diarias en un tiempo de alimentacion designado. La variante mas popular implica 16 horas de ayuno y ocho horas en las que puedes comer. No obstante, las versiones mas extremas, que han demostrado tener algunos beneficios para la salud, tambien estan ganando terreno, especialmente entre los asistentes al gimnasio.","There are technical advantages to determining whole body protein synthesis and breakdown, because no muscle biopsies are required and frequent blood sampling enables reasonable calculation of both synthesis and breakdown during amino acid or protein absorption. The anabolic response can only be determined when synthesis and breakdown are measured simultaneously. However, measurement of protein synthesis and breakdown at the whole body level is also of value when evaluating the anabolic response.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38517408507&p=1pl&v=1&x=PZHXVgxkt9s4rBxEsGTJCg
10.1038/s41588-019-0423-x,Biology_easy_530,"""You can take the time to consider the options and make sure you get the right treatment,"" Weiser said.","2b ), they were not enriched for CRC drivers (defined based on IntOGen and The Cancer Genome Atlas (TCGA) ) or a published list of pan-cancer drivers Supplementary Fig.","Curtis stressed that the findings do not diminish the importance of colon cancer screening to catch the disease early. But if that risk has more to do with tumor genetics than with time, patients may feel less pressure to make an immediate decision. ""You can take the time to consider the options and make sure you get the right treatment,"" Weiser said.","private high-frequency sSNVs than the primary tumor (P = 0.020, Wilcoxon rank-sum test; Fig. 2b ), they were not enriched for CRC drivers (defined based on IntOGen and The Cancer Genome Atlas (TCGA) ) or a published list of pan-cancer drivers Supplementary Fig. These data reflect limited driver-gene heterogeneity between P/M pairs and suggest that few additional private genomic drivers were required for metastasis when the primary CRC is already advanced.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39491155360&p=1pl&v=1&x=39D9f5388GEpMnvvnV5u4Q
10.1016/j.cell.2016.09.025,Biology_easy_531,The difference between the groups is driven by the younger African Americans (30 - 40 yr. old).,"Likewise, we can obtain the reduced expression vectors from M where the fold change residuals are derived from the differences between infected and non-infected samples residuals for each individual j from which a valid sample of each condition was collected: ε","The researchers showed that African Americans mounted significantly higher neutralizing and IgG antibody titers to H1N1 compared to Caucasians, indicating better protection. The difference between the groups is driven by the younger African Americans (30 - 40 yr. old). They also observed that the heightened response in African Americans diminishes with age; there was no significant response difference in older African Americans (>65 yr. old) compared to Caucasians.","From a merely formal point of view, the P ST statistics is just the coefficient of determination R 2 associated to the regression model that defines the reduced expression vectors. Likewise, we can obtain the reduced expression vectors from M where the fold change residuals are derived from the differences between infected and non-infected samples residuals for each individual j from which a valid sample of each condition was collected: ε Moreover, the Pst coefficients obtained from model M 3 , can be also obtained from M For each site, and separately for each population, we simulated 500 allele frequency trajectories.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/u-Ok09lkzD8/ethnicity-influences-response-influenza-vaccine-04313.html
10.1073/pnas.1810596115,Biology_easy_532,"""Our results suggest at least two different ways in which the brain has evolved to anticipate the future,"" said Breska.","In three conditions, participants detected a target embedded in a visual stream (Fig.","Ultimately, the results confirm that the brain uses two different mechanisms for anticipatory timing, challenging theories that a single brain system handles all our timing needs, researchers said. ""Our results suggest at least two different ways in which the brain has evolved to anticipate the future,"" said Breska. ""A rhythm-based system is sensitive to periodic events in the world such as is inherent in speech and music,"" he added.","This double dissociation constitutes causal evidence in favor of distinct computational and neural mechanisms for interval-and rhythm-based temporal prediction, and highlights the contribution of these subcortical structures to attentional orienting. In three conditions, participants detected a target embedded in a visual stream (Fig. In the ""single-interval"" condition, the target timing was predictable based on aperiodic repeated presentation of pairs of stimuli that defined the target interval.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37749877016&p=1pl&v=1&x=OmFz0NnXqLnYTmJvjsX7tw
10.1098/rspb.2017.2733,Biology_easy_533,"The researchers also note that, in addition to helping big business, further study of these relationships would also inform our understanding of the ecology and evolution of both insects and yeasts.","Such cases might be in the minority, however.","While the bulk of the available research focuses on individual yeasts or insect species (like fruit flies), our overarching review of the literature finds that this mutually beneficial phenomenon likely holds true for many different insect species and for many types of yeast. These are some of the same traits that make yeasts attractive to insects. The researchers also note that, in addition to helping big business, further study of these relationships would also inform our understanding of the ecology and evolution of both insects and yeasts.","In some cases, specificity appears to be due to selectivity on behalf of the insects. Such cases might be in the minority, however. One can imagine a scenario in which yeasts attract the insects most likely to vector them to the sugar or other food resources on which they best grow.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33616614508&p=1pl&v=1&x=5b64fVPPm7h-Gh82xeMicA
10.1016/j.celrep.2014.08.055,Biology_easy_534,"""OCT4 also represses neuronal differentiation, so we think that the loss of that repression with BRD4 inhibition is the most likely reason for the induction of neuronal characteristics in the stem cells,"" says Dr. Di Micco.",In Fig.,"These genes, including OCT4 and PRDM14, showed steep drops in expression when Dr. Di Micco applied BRD4 inhibitors to stem cells. ""OCT4 also represses neuronal differentiation, so we think that the loss of that repression with BRD4 inhibition is the most likely reason for the induction of neuronal characteristics in the stem cells,"" says Dr. Di Micco. The new findings suggest that BRD4 enforces stem cell identity from an even higher regulatory level in the cell.","This normalization enables the comparison of initiating/elongating regions separately between treatments. In (a), a subset of BRD4 peaks was selected such that the distributions of BRD4 intensities of enhanceroverlapping BRD4 peaks are statistically indistinguishable between SE-overlapping and TE-overlapping BRD4 peaks (identical quartiles and pvalue=0.5 using a t-test). In Fig.",[1],Biology,train,1.0,news,http://www.newswise.com/articles/scientists-identify-key-factor-that-maintains-stem-cell-identity
10.1038/s41467-018-04532-x,Biology_easy_535,"The findings, published in Nature Communications, bring the field one step closer to application.",In Fig.,"Complete randomness in the structures of superconductors and insulators could lower the requirements of pristine crystalline ordering -- and make them more accessible to industry. The findings, published in Nature Communications, bring the field one step closer to application. While topological superconductors might not exist in nature, they can be fabricated, as the study demonstrates.","This is a consequence of a topological edge mode enclosing a finite system and is directly observable as discussed below. In Fig. In the topological phase, the system exhibits a quantized thermal conductance which is a direct consequence of the nontrivial topology.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34220879760&p=1pl&v=1&x=KKEOXU_X6EpTgaB2jAyoyQ
10.1016/j.cub.2018.02.030,Biology_easy_536,"Controlling the amount of light a hamster receives in the lab can delay arrival of puberty, which comes around 30 days of age for ""long-day"" hamsters and around 100 days of age or later for ""short-day"" hamsters.","Nevertheless, caveats must be considered when using the seasonal-species approach.","From play to dominance

Using a seasonal breeding species, like Siberian hamsters, allowed researchers to control the timing of puberty. Controlling the amount of light a hamster receives in the lab can delay arrival of puberty, which comes around 30 days of age for ""long-day"" hamsters and around 100 days of age or later for ""short-day"" hamsters. With two groups going through puberty at different times, researchers can observe behavioral changes in each group to determine whether these changes are always locked to puberty.","Finally, SD rearing more accurately mimics the prepubertal state by altering the development of the entire reproductive axis rather than just the gonads. Nevertheless, caveats must be considered when using the seasonal-species approach. SD housing of adult Syrian hamsters increases the steroid sensitivity of neural circuits regulating territorial aggression of females but decreases the steroid sensitivity of the neural circuits regulating the sex behavior of males and females 28].",[1],Biology,train,1.0,news,https://www.futurity.org/hormones-teen-social-behavior-1707962/
10.1038/s41467-018-03902-9,Biology_easy_537,The discovery of this new checkpoint in gene expression could be used for the development of new antibiotics.,"1c) , suggesting that the transcription complexes synthesized 6-mer RNA and paused.","'The fact that the RNAP can be simultaneously bound to the DNA and the short piece of RNA for a longer period of time was very surprising, as it contradicts current knowledge,' says Dr. Dulin. The discovery of this new checkpoint in gene expression could be used for the development of new antibiotics. 'For example, it may be possible to develop medication that locks the RNAP in the paused state, thus killing the bacteria that cause illnesses,' says Dr. Dulin.","1b and Supplementary Fig. 1c) , suggesting that the transcription complexes synthesized 6-mer RNA and paused. The second population comprised ITCs that returned from the PS to the US state (Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33988829961&p=1pl&v=1&x=sIyhc04yVa3V5dJPA2VSbg
10.1111/j.1752-8062.2011.00370.x,Biology_easy_538,The public chose well.,This species might serve as a reverse translational model for atherosclerosis resistance.,... All hail Holly whose healthy heft will help her hibernate until the spring. The public chose well. She gained a lot of weight!,"Brown bears tolerate elevated cholesterol levels, obesity, physical inactivity, and circulatory slow fl ow during hibernation without signs of atherosclerosis. This species might serve as a reverse translational model for atherosclerosis resistance. Th e experimental design of recaptuing provides controls for both internal and external eff ects (body and external temperature, feeding status, metabolic rate) in accordance with recommendations by Carey et al.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=40332148373&p=1pl&v=1&x=cJpDRN-beE4AfuXMTYykaw
10.1016/j.cub.2018.07.021,Biology_easy_539,"It's a dangerous world for a solo meerkat.""",The telomere assay had very late amplification in the no template control (NTcalC) (Ct > 26.95).,"A lucky few start their own group and become dominant breeders. ""Away from the group there is no early warning system, and meerkats are easy prey for eagles, goshawks and caracal. It's a dangerous world for a solo meerkat.""",Dissociation curves showed a single peak for both assays in all reactions. The telomere assay had very late amplification in the no template control (NTcalC) (Ct > 26.95). This was deemed to be late formation of primer-dimer and acceptable considering the highest Ct of our DNA samples (17.37) .,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34959348511&p=1pl&v=1&x=1MgMG7oRGbJVjC1G5Ie3GA
10.1038/s41467-018-04738-z,Biology_easy_540,"""Economic optimization can be quite effective in reducing current greenhouse-gas emissions, it certainly has its strengths.","Note, that the division of state space into acceptable and unacceptable states is not identical for all polices, but depends on the rewards receivable through executing a policy.","All of these turn out to have their benefits and deficits, yet the profit-maximizing approach shows the greatest likelihood of producing outcomes that harm people or the environment. ""Economic optimization can be quite effective in reducing current greenhouse-gas emissions, it certainly has its strengths. Even for relatively high risks, and even if profit-maximizing agents in our calculations are far-sighted, they tend to accept the possibility of detrimental environmental and societal impacts.""","Based on the Brundtland Commission's report on sustainable development 26 a sustainable policy should fulfill two requirements: First, meet the needs of the present. Note, that the division of state space into acceptable and unacceptable states is not identical for all polices, but depends on the rewards receivable through executing a policy. Second, a sustainable policy should sustain the ability to meet the needs of the future 26 .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34322701711&p=1pl&v=1&x=vJJD8AB_eJNeMdvdg2kC-g
10.1038/s41467-018-03926-1,Biology_easy_542,"""We tried a few approaches, but none seemed to work convincingly"", said Danelon.","Alkaline conditions hydrolyze RNA and separate DNA strands, allowing to separate unfolded ssDNA according to their respective sizes.","Combining the Japanese system with a module for DNA replication proved difficult. ""We tried a few approaches, but none seemed to work convincingly"", said Danelon. ""Viruses are very intriguing from a molecular biology point of view"", said Van Nies.","Following the same protocol but omitting the column purification step prevents the DNA from running into the gel. Alkaline conditions hydrolyze RNA and separate DNA strands, allowing to separate unfolded ssDNA according to their respective sizes. A small fraction (ca.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33847806434&p=1pl&v=1&x=nY5fA_k2gkansUzroWPH1A
10.1038/s41477-018-0249-z,Biology_easy_545,New episodes are ready weekday mornings so you can listen on your morning commute.,3a and Supplementary Fig.,"Detecting when the ripening switch is ready to be thrown gives produce growers a clearer shot at the perfect ripening window. And if they can apply it to a range of fruits, that could mean even more variety for us in the supermarket aisles. New episodes are ready weekday mornings so you can listen on your morning commute.","We could then mutate the EIN3 binding motif in the RIN promoter and the RIN binding motif in the ACS2 promoter, both of which disrupted the spontaneous ethylene synthesis ( Fig. 3a and Supplementary Fig. These results confirmed that the exogenous tomato ACS2 and MADS genes are responsible for the observed ethylene burst.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37195228032&p=1pl&v=1&x=vULEBp3cDUvW_xMAAr-xkQ
10.1016/j.cell.2018.06.012,Biology_easy_546,Note: material may have been edited for length and content.,"Importantly, the basal ganglia direct and indirect pathways interact distinctly with these different controllers.","At the same time, by identifying how different cell types in the brain control our behavior, it provides new insight into potential treatments for different neurological diseases."" Note: material may have been edited for length and content. For further information, please contact the cited source.","Together, these data suggest that the learned action sequence is likely organized in a hierarchical manner, with both local subsequence-level and global sequence-level controls. Importantly, the basal ganglia direct and indirect pathways interact distinctly with these different controllers. Similar to the observations in the LLRR sequence, brief stimulation (100 ms) of iSPNs after the first press of the LLLRRR sequence ablated the entire left subsequence, removing multiple upcoming left presses well beyond the stimulation period (Figures 5G and 5H) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34425568667&p=1pl&v=1&x=kttWziQnmbJXslRMYzR9Jw
10.1177/0748730403253585,Biology_easy_547,And you won't even need a flashlight behind your knee.,"Thus, the increase in this jet lag scale was fairly small.","Given this knowledge of circadian rhythms, one can -- as one article title claimed -- ""trick Mother Nature"" into letting you fly around the world without jet lag. And you won't even need a flashlight behind your knee. Please send suggestions to Mind Matters editor Gareth Cook, a Pulitzer prize-winning journalist at the Boston Globe.","The highest mean score that occurred was 11 (out of a possible 36), and this occurred in the dim light group on the 3rd treatment day and in the intermittent light group on the 2nd and 3rd treatment days. Thus, the increase in this jet lag scale was fairly small. There was a significant main effect of section of study, [F(3,75) = 9.62, p < 0.001], and a significant section of study by light group interaction, [F(6,75) = 2.56, p = 0.044], but no significant main effect of group.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=how-to-prevent-jet-lag
10.1073/pnas.1702798114,Biology_easy_548,"It's a completely new and novel strategy to tackle this issue,"" Sheppard says.",Biofilm disruption was associated with a marked reduction in hyphae-associated GAG as detected by lectin staining (Fig.,"The team's research, which appears in the Proceedings of the National Academy of Sciences, creates a promising avenue for the development of innovative strategies to treat a wide variety of diseases and hospital-acquired infections like pneumonia, as well as bloodstream and urinary tract infection. It's a completely new and novel strategy to tackle this issue,"" Sheppard says. These enzymes are the first strategy that has ever been effective in eradicating mature biofilms, and that work in mouse models of infection,"" adds Sheppard.","Treatment with Sph3 h for 1 h disrupted established A. fumigatus biofilms with an effective concentration for 50% activity (EC 50 ) of 0.45 ± 1.31 nM (Fig. Biofilm disruption was associated with a marked reduction in hyphae-associated GAG as detected by lectin staining (Fig. A catalytic variant Sph3 h D166A, which does not mediate GAG hydrolysis , displayed a greater than 500-fold reduction in antibiofilm activity (Fig.",[1],Biology,train,1.0,news,http://www.futurity.org/biofilm-microbes-enzymes-1466602/
10.1186/1472-6882-6-39,Biology_easy_549,But it doesn't have to be so hard.,"In our study, cinnamon, clove, geranium, lemon, lime, orange and rosemary oils exhibited strong activity against the selected bacterial strains.","But it doesn't have to be so hard. Your home will go back to smelling as fresh and bright as it looks, and you'll spend a lot less time wrinkling your nose the second you step in the door. Whether you're cleaning with ingredients that stop the source of malodors in their tracks or keeping your air fresh, filtered and scented with essential oils, these are the keys to making sure your home always smells great.","In vitro studies in this work showed that the essential oils inhibited bacterial growth but their effectiveness varied. In our study, cinnamon, clove, geranium, lemon, lime, orange and rosemary oils exhibited strong activity against the selected bacterial strains. Even though earlier studies have reported better antimicrobial activity for eucalyptus oil our study showed least inhibitory activity of eucalyptus in addition to aniseed and camphor oils.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38333045251&p=1pl&v=1&x=3oeAumBFT2BybbhrgComfg
10.1111/1365-2656.12311,Biology_easy_550,"By comparing grasshoppers found at woodland sites once used for agriculture to similar sites never disturbed by farming, Hahn and Orrock show that despite decades of recovery, the numbers and types of species found in each differ, as do the understory plants and other ecological variables, like soil properties.",pseudo-R 2 ).,"By comparing grasshoppers found at woodland sites once used for agriculture to similar sites never disturbed by farming, Hahn and Orrock show that despite decades of recovery, the numbers and types of species found in each differ, as do the understory plants and other ecological variables, like soil properties. The findings have implications for conservationists, land-use planners, policymakers and land managers looking to prevent habitat destruction or promote ecological recovery of natural spaces. Hahn and Orrock suggest new strategies may be needed in these disturbed environments.","Total number of grasshoppers collected at the Savannah River Site, South Carolina, USA in three 5 m 9 5 m plots per site regressed against herbaceous cover (averaged across the three plots and centred). pseudo-R 2 ). *P ≤ 0Á05; **P ≤ 0Á01; ***P<0.001.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/11/141124160456.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_society+%28Top+Society+News+--+ScienceDaily%29
10.1038/ng.3916,Biology_easy_551,"""We spent a lot of evenings out there making a dent in his very nice cellar,"" Moir says.",Gene-wide analysis of TREM2 showed a genome-wide significant association (P SKAT = 1.42 × 10 −15 ) (Supplementary Tables 10 and 11) .,"""I was like, well, what does that mean?"" ""We spent a lot of evenings out there making a dent in his very nice cellar,"" Moir says. ""Maybe amyloid plaques are a brain pearl,"" Moir says, ""a way for our body to trap and permanently sequester these invading pathogens.""","These variants are not in linkage disequilibrium (Supplementary Table 14) , and conditional analyses confirmed that p.Arg62His and p.Arg47His are independent risk variants (Supplementary Fig. Gene-wide analysis of TREM2 showed a genome-wide significant association (P SKAT = 1.42 × 10 −15 ) (Supplementary Tables 10 and 11) . Removal of p.Arg47His and the p.Arg62His variants from the analysis diminished the genewide association, but the signal remained interesting (P SKAT-O = 6.3 × 10 −3 , P Burden = 4.1 × 10 −3 ).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33329016373&p=1pl&v=1&x=47prfIJfMfIWS28CMR-xlw
10.1038/s41593-019-0365-8,Biology_easy_552,"This study is an example of how SickKids is making Ontario healthier, wealthier and smarter (www.healthierwealthiersmarter.com).","In future experiments, lawns could be engineered to contain specific excitatory subtypes by Ngn2 overexpression 28 or to express optically or chemically gated modulators of activity that expand the range of possible testable phenotypes.","The strength of the stem cell based approach is that it produces human nerve cells to study autism in the lab. The changes seen in the lab may have occurred prior to the behavioural changes related to autism, and this may limit the translation of the research into clinical settings. This study is an example of how SickKids is making Ontario healthier, wealthier and smarter (www.healthierwealthiersmarter.com).","We showed cell autonomous effects by assessing morphology and electrophysiology of R841X on control and mutant lawns. In future experiments, lawns could be engineered to contain specific excitatory subtypes by Ngn2 overexpression 28 or to express optically or chemically gated modulators of activity that expand the range of possible testable phenotypes. Moreover, SparCon can be adapted to use other cell type-specific promoters such as hvGAT to selectively label inhibitory neurons 29 or GDAP1L1 30 to restrict analyses to neurons of similar age and electrophysiological properties.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38903747903&p=1pl&v=1&x=NHwORxj2_z4EMPc6R5egQg
10.1126/science.1250217,Biology_easy_554,Researchers found that the yeast cells have about 50 main ways in which they react to any drug.,"Fluconazole inhibits the protein Erg11, thus demonstrating the ability of HIP to identify targets in vivo (Fig.","For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us. Researchers found that the yeast cells have about 50 main ways in which they react to any drug. This relatively small number of gene signatures means that it might be possible to eventually use a person's genome to predict their drug response.","For example, the Erg11D /ERG11 strain represents a ""hit"" as it had the largest FD in the fluconazole HIP profile and passed significance and specificity thresholds . Fluconazole inhibits the protein Erg11, thus demonstrating the ability of HIP to identify targets in vivo (Fig. Fluconazole HOP identified mechanisms that buffer the ergosterol pathway, including the requirement for iron (Fig.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140410141916.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.cmet.2016.09.014,Biology_easy_555,They found that those cultures exposed to air containing varied amounts of oxygen (between 5% and 8%) became synchronized to a new circadian rhythm.,"** p < 0.01, *** p < 0.001, N.S -Non Significant.","While it remains unclear at this time if altering the oxygen content of the air we breathe could be an effective way to overcome jet lag in humans, Dr. Asher's team believes that airlines may want to try and alter the amount of oxygen that is in the air that passengers on their planes breathe. They found that those cultures exposed to air containing varied amounts of oxygen (between 5% and 8%) became synchronized to a new circadian rhythm. The 16% oxygen mice were found to adapt to the new day-night schedule significantly quicker than their counterparts, the researchers found, based on observations of their eating, sleeping, and overall activity levels.","J., The distribution of the number of days that took the two different mouse strains to adopt the new lighting schedule are presented together with the mean ± SD (4.9 ± 0.2 and 6.3 ± 0.2 days for Hif1α +/+ and Hif1α +/littermates respectively, p value 0.0004, n=15). ** p < 0.01, *** p < 0.001, N.S -Non Significant. Genomewide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver.",[1],Biology,train,1.0,news,http://www.redorbit.com/news/health/1113416286/jet-lag-cure-102416/
10.1038/s41467-018-04140-9,Biology_easy_556,"""This study represents an important step towards better understanding the HLB disease mechanism, which will help us develop novel approaches to control this unstoppable disease,"" Ma said.",5) .,"""In the diseased trees we studied, the protein levels of some PLCPs were increased, presumably attempting to combat the bacterial infection,"" Ma said. This study is among the first to describe the molecular tactics employed by CLas to colonize citrus plants. ""This study represents an important step towards better understanding the HLB disease mechanism, which will help us develop novel approaches to control this unstoppable disease,"" Ma said.","The results show that while PtoDC3000Δcip1 and the EV control exhibited strong reductions in virulence compared to wild-type PtoDC3000, expression of SDE1 partially, but significantly, complemented this virulence deficiency (Fig. 5) . Collectively, these results suggest that SDE1 promotes bacterial infection, likely by inhibiting PLCP activity in plant hosts.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33931193847&p=1pl&v=1&x=JkkaF22Itix2BOzYIRHmpQ
10.1038/s41467-017-01333-6,Biology_easy_557,"Most mice learn to shut their eyes when they see the light blink, to avoid the irritation of the coming air puff.","In addition, conditional knockout of UBC13 led to little or no difference in the rise time of mEPSCs and to a modest increase in the decay time of mEPSCs (Supplementary Fig.","When the researchers tested their ability to learn motor skills, however, the mice without RNF8 failed miserably. Most mice learn to shut their eyes when they see the light blink, to avoid the irritation of the coming air puff. After a week of training, mice with a functioning copy of the gene closed their eyes in anticipation more than three quarters of the time, while mice without the gene shut their eyes just a third of the time.","Expression of RNF8ResR42A failed to reverse the RNF8 knockdown-induced presynaptic bouton phenotype in the cerebellum in vivo. In addition, conditional knockout of UBC13 led to little or no difference in the rise time of mEPSCs and to a modest increase in the decay time of mEPSCs (Supplementary Fig. Together, these data reveal that the structural alterations in parallel fiber/Purkinje cell synapse development in UBC13 conditional knockout mice bear functional consequences on synaptic neurotransmission.",[1],Biology,train,1.0,news,http://www.futurity.org/autism-brain-gene-synapses-1598072/
10.1073/pnas.1515348112,Biology_easy_558,"The hunt continues

Clardy's team hasn't yet determined the role of the three new molecules, but the likelihood that the genes are being transferred from colony to colony makes the researchers suspect they're important for the ants in some way.","A weak correlation between the methyl group protons and the β-protons of the α-methyl-L-serine, along with the HSQC and HMBC data, helped corroborate the identity of this unusual amino acid.","""It suggests that these genes are moving around in the environment from bacterium to bacterium,"" he said. The hunt continues

Clardy's team hasn't yet determined the role of the three new molecules, but the likelihood that the genes are being transferred from colony to colony makes the researchers suspect they're important for the ants in some way. He also suspects that what they found isn't an anomaly.","The chloro-and hydroxysubstitutions distinguished the aliphatic proton signals of each piperazic acid, giving rise to distinct patterns in the COSY for each of the three similar residues. A weak correlation between the methyl group protons and the β-protons of the α-methyl-L-serine, along with the HSQC and HMBC data, helped corroborate the identity of this unusual amino acid. Facile crystallization of gerumycin occurred in 50% acetonitrile/water to form colorless block crystals.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/-4IUOlhi2UE/
10.1002/etc.2793,Biology_easy_559,"However, it should go without saying that things can be overlooked.",Metformin was below the limit of detection in control samples and was found at 41 AE 8 mg/L in treatment samples.,"Water pollution is not exactly an underappreciated concern. However, it should go without saying that things can be overlooked. That appears to be the case concerning pollution from a common diabetic drug, which may now be poisoning fish in Lake Michigan.",The link between insulin signaling and steroidogenesis indicates the potential for antidiabetic drugs including metformin to act as endocrine disruptors. Metformin was below the limit of detection in control samples and was found at 41 AE 8 mg/L in treatment samples. No differences in expression were found in the liver between treatment or sex for the metabolic genes GK (2-way ANOVA:,[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/11583/20150102/lake-michigan-being-poisoned-diabetes-drugs.htm
10.1038/ncomms2744,Biology_easy_560,"But the larvae could live and develop normally if all they ever ate were their fellow maggots: a cannibalistic diet was sufficient, though they develop more slowly and don't grow to be as large.","4b ; difference in slopes F 1,10 = 5.8, P = 0.037).","Those who were malnourished in the lab were more likely to have cannibalistic tendencies. But the larvae could live and develop normally if all they ever ate were their fellow maggots: a cannibalistic diet was sufficient, though they develop more slowly and don't grow to be as large. Check out some videos here.","Second, larvae from the Selected populations aggregated significantly faster around experimentally injured victims ( Fig. 4b ; difference in slopes F 1,10 = 5.8, P = 0.037). Both these differences are heritable; because the assayed Selected and Control larvae and their parents were raised on standard food prior to these assays, the effect of individual experience or maternal environment can be excluded.",[1],Biology,train,1.0,news,http://www.popsci.com/science/article/2013-05/what-cannibals-could-teach-us-about-evolution
10.1126/scitranslmed.3010134,Biology_easy_561,"This blend of academic excellence and its real-world application feeds into ImperialaEUR(tm)s exceptional learning environment, where students participate in research to push the limits of their degrees.",RNA sequencing showed comparable total TTN transcript levels in patients with or without TTNtv (Fig.,"A real-time transcript will be viewable at http://rcc.intercall.com/. This blend of academic excellence and its real-world application feeds into ImperialaEUR(tm)s exceptional learning environment, where students participate in research to push the limits of their degrees. It has increased the volume of applied health research for the benefit of patients and the public, driven faster translation of basic science discoveries into tangible benefits for patients and the economy, and developed and supported the people who conduct and contribute to applied health research.","In addition, we deduced that a linear positional effect of TTNtv implied that mutant proteins produced dominant negative effects. RNA sequencing showed comparable total TTN transcript levels in patients with or without TTNtv (Fig. Moreover, the relative expression of TTNtv and of other single-nucleotide polymorphisms (SNPs) distributed throughout TTN transcripts showed robust expression of both alleles (Fig.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/titin-gene-mutations-will-help-identify-patients-at-risk-of-heart-failure/
10.1073/pnas.1708805114,Biology_easy_562,"Potential impact

About one in 100 people who receive hip or knee replacements experience an infection, according to the American Academy of Orthopaedic Surgeons.",The results demonstrate that among Csg-related amyloidogenic proteins the antiamyloid activity of both WT-TTR and M-TTR is not sequence-specific.,"""We found that TTR can prevent biofilm formation in a uropathogenic E. coli strain as well as other bacterial strains."" Potential impact

About one in 100 people who receive hip or knee replacements experience an infection, according to the American Academy of Orthopaedic Surgeons. ""It's possible that products derived or based on these protein interactions could reduce this problem in medicine, that biofilms form on a lot of artificial surfaces implanted within the body,"" Buxbaum says.","CsgA, 15hr CsgA+WT-TTR, 15hr CsgA+M-TTR, 15hr amyloid, whereas WT-TTR did not significantly alter CsgB trunc fibril formation (Fig. The results demonstrate that among Csg-related amyloidogenic proteins the antiamyloid activity of both WT-TTR and M-TTR is not sequence-specific. (Fig.",[1],Biology,train,1.0,news,http://www.futurity.org/ttr-protein-fights-biofilm-1596272/
10.1002/ece3.1068,Biology_easy_563,(Photo : Flickr: Derek B.,"The significant Mantel correlations ranged from 0.1915 to 0.2159 and were slightly stronger than the correlation with Euclidian distance (r M = 0.1913); however, all confidence intervals overlapped (Fig.","(Photo : Flickr: Derek B. ""We have found that it is increasingly difficult for Maine and New Hampshire cottontails to travel the large distances between fragmented habitats necessary to maintain gene flow among populations of cottontail,"" Kovach explained. Once you have a more mature forest, the cottontail habitat is reduced.""","For the Mantel tests comparing our hypothesized cost distances with cottontail genetic distance across the entire study area, all of the dispersal models, except the logarithmic road model, were statistically significant. The significant Mantel correlations ranged from 0.1915 to 0.2159 and were slightly stronger than the correlation with Euclidian distance (r M = 0.1913); however, all confidence intervals overlapped (Fig. 6) .",[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/8213/20140723/saving-new-england-cottontail.htm
10.1016/j.stem.2017.02.014,Biology_easy_564,This approach has revealed new insights into the timing and coordination of the changes in gene activity and modifications to the DNA that occur as cells are reprogrammed from one state to another.,We obtained similar results using the WIBR3 PSC line under 5i/L/FA conditions ( Figure S5B ).,"By recognising the flags, researchers can now accurately track and investigate stem cells as the cells transition between different states. This approach has revealed new insights into the timing and coordination of the changes in gene activity and modifications to the DNA that occur as cells are reprogrammed from one state to another. These findings will open up new ways to improve the efficiency of cell reprogramming and to drive stem cells to become different types of specialised cell.","We continued to maintain N4 + cells under naive PSC culture conditions for over 20 passages, and the cells generated stable naive PSC lines ( Figure 6F ). We obtained similar results using the WIBR3 PSC line under 5i/L/FA conditions ( Figure S5B ). To improve the usability of our approach, we refined the set of antibodies and found that a combination of two naive-specific markers (CD75 and CD130) and two primed-specific markers (CD24 and CD57) could largely recapitulate the full antibody panel.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/a-tale-of-2-states/
10.1038/s41467-019-08499-1,Biology_easy_566,"The mixing of such different types of fluids probably enhances the conditions that can support microbial life, leading to higher diversity and providing new opportunities to take advantage of their ""gassy"" environment.","However, this is unlikely for the SJ3.","He noted that the volcanic gas that ends up in SJ3 is very different from the gases that are present in our atmosphere in that it lacks oxygen. The mixing of such different types of fluids probably enhances the conditions that can support microbial life, leading to higher diversity and providing new opportunities to take advantage of their ""gassy"" environment. Comparing SJ3 to a buffet, Colman said, ""Just like a greater variety of food attracts more and different types of people, so does a hot spring that offers a variety of chemical conditions.""","Nevertheless, here and in other comparisons, it is possible that the lack of genome completeness could lead to the apparent absence of some functional gene homologs. However, this is unlikely for the SJ3. Bin34 MAG owing to its high estimated completeness (~99%) and other lines of evidence suggesting the potential for hydrogenotrophic methanogenesis.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38659154593&p=1pl&v=1&x=2fk4UflVCFGC6rwI4eBVzg
10.1038/s41586-018-0772-0,Biology_easy_567,"""We found that the ability of CA2 cells to efficiently activate the lateral septum is greatly enhanced when vasopressin is released in the lateral septum,"" said Dr. Siegelbaum.",We observed no difference related to sex and the results were pooled together.,"""Further along in the interaction between the two mice, a signal generated in CA2 is sent to the lateral septum, which facilitates aggressive behavior."" ""We found that the ability of CA2 cells to efficiently activate the lateral septum is greatly enhanced when vasopressin is released in the lateral septum,"" said Dr. Siegelbaum. ""Previous research had revealed a link between vasopressin and aggression, and CA2 appears to lie at the center of this effect.""","χ 2 test, **P = 0.008. We observed no difference related to sex and the results were pooled together. No statistical methods were used to predetermine sample size, but sample sizes are consistent with those generally employed in the field.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37894688052&p=1pl&v=1&x=iuWRkyFSsqVZLoaDbYQOmg
10.1038/s41586-019-1005-x,Biology_easy_570,"""We can get rid of it.","Consistent with these results, mass-spectrometry analysis of metabolites identified increased levels of TCA cycle intermediates and ATP levels upon BACH1 knockdown (Extended Data Fig.","""We found we could basically put a thumb on this trouble-making BACH1 protein,"" Rosner said. ""We can get rid of it. We can do that with heme.","These data suggest that loss of BACH1 promotes mitochondrial respiration. Consistent with these results, mass-spectrometry analysis of metabolites identified increased levels of TCA cycle intermediates and ATP levels upon BACH1 knockdown (Extended Data Fig. We also observed a decrease in the steady-state levels of multiple intermediates in the glycolysis pathway, including glucose-6-phosphate (G6P), fructose-6-phosphate (F6P), fructose-1,6-bisphosphate (F16BP), dihydroxyacetone phosphate/glyceraldehyde 3-phosphate (DG3P) and lactate in shBACH1 cells.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38704198175&p=1pl&v=1&x=0iHPZkZx9iXcC0RfZfNJbg
10.1126/sciadv.aaq0333,Biology_easy_571,"And even before the shark fin soup craze picked up, miles-long nets fitted with thousands of hooks to catch massive tuna inadvertently caught the big sharks.","Thus, it cannot be excluded that subsistence fishing by local Chagossians Table 2 .","The reef, for example, lacks some of the biggest sharks -- like Mako and Tigers -- which very well could have been done in by overfishing, even in the open sea, farther from the Chagos islands. And even before the shark fin soup craze picked up, miles-long nets fitted with thousands of hooks to catch massive tuna inadvertently caught the big sharks. ""In the 50s and 60s, for every tuna you could catch five or six sharks,"" said Ferretti.","Therefore, although we cannot be sure of the impact of the bank fishery on shark populations around the Chagos archipelago, anecdotal evidence suggest that reef sharks were being depleted across the WIO ( . Thus, it cannot be excluded that subsistence fishing by local Chagossians Table 2 . Model fit is indicated by its relative WAIC.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=33502636256&p=1pl&v=1&x=KD_l9fQxspqaPu9fkAkAhg
10.3389/fphar.2013.00071,Biology_easy_572,"After taking their daily dose for 10 days, they found that those who consumed the drink reported feeling significantly better than people popping the pill.",The primary function of Th17 cells appears to be the clearance of pathogens that are not adequately handled by Th1 or Th2 cells and they are potent inducers of tissue inflammation ( .,"One analysis found that the polyphenols in cocoa may have a positive impact on your T cells, which help keep your immune system functioning properly. After taking their daily dose for 10 days, they found that those who consumed the drink reported feeling significantly better than people popping the pill. It tastes good and adds a solid ""bite"" to your favorite meals and drinks.","After naïve Th cell activation and proliferation, effector Th lymphocytes appear. The primary function of Th17 cells appears to be the clearance of pathogens that are not adequately handled by Th1 or Th2 cells and they are potent inducers of tissue inflammation ( . No changes in the secretion of this cytokine were observed in splenocytes , although others found increased values , and in vitro studies demonstrated a suppression of IFN-γ production by PHA-stimulated PBMC (Jenny et al., 2009) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=32774827940&p=1pl&v=1&x=iRPjlQENKX1MIkVFX6UuxQ
10.1038/ng.955,Biology_easy_573,Their life expectancy is 12 years fewer than noncarriers.,"Ovarian tumors from BRIP1 mutation carriers show loss of the wild-type allele, suggesting that the BRIP1 gene behaves like a classical tumor suppressor gene in ovarian cancer and that tumors with bi-allelic loss of BRIP1 may be good targets for therapeutic agents that affect DNA repair pathways.","But the most significant feature of deCODE's research effort may be its capacity to yield insights into cancer epidemiology and biomarker discovery. Their life expectancy is 12 years fewer than noncarriers. These insights can be applied to other populations, as well.","Furthermore, the lives of BRIP1 mutation carriers are on average 3.6 years shorter than those of non-carriers. Ovarian tumors from BRIP1 mutation carriers show loss of the wild-type allele, suggesting that the BRIP1 gene behaves like a classical tumor suppressor gene in ovarian cancer and that tumors with bi-allelic loss of BRIP1 may be good targets for therapeutic agents that affect DNA repair pathways. Because of the relatively low prevalence of ovarian cancer, apparently sporadic cases may actually be caused by rare mutations that have large effects.",[1],Biology,train,1.0,news,http://www.newsweek.com/vikings-might-slay-cancer-354895
10.1038/s41598-019-40546-1,Biology_easy_574,"It feels like Yuka was waiting for me to find her.""",Nucleus-like structures found in the tissue homogenate were histone-and lamin-positive by immunostaining.,"""I'm so happy with this latest research. It feels like Yuka was waiting for me to find her."" ""I was so moved when I saw the cells stir.","Proteomic analyses demonstrated the presence of nuclear components in the remains. Nucleus-like structures found in the tissue homogenate were histone-and lamin-positive by immunostaining. In the reconstructed oocytes, the mammoth nuclei showed the spindle assembly, histone incorporation and partial nuclear formation; however, the full activation of nuclei for cleavage was not confirmed.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38785874512&p=1pl&v=1&x=wao7bdwTiST6qQUEdMcKew
10.1038/s41587-019-0088-0,Biology_easy_575,"**During apoptosis, biochemical regulatory pathways ensure the death of targeted cells.","With lower regularization parameters, the model fit is better but has worse predictive power as shown by leaveone-time-point-out cross-validation (Fig.","He sees pseudodynamics as ""the first tool of basic research that will allow vital questions facing biology to be examined at the single-cell level."" **During apoptosis, biochemical regulatory pathways ensure the death of targeted cells. This can be necessary in order to reduce the number of cells in a tissue or in order to remove damaged cells.","Pseudodynamics was able to fit the samples along this transcriptomic trajectory and allowed imputation of unobserved time points (Fig. With lower regularization parameters, the model fit is better but has worse predictive power as shown by leaveone-time-point-out cross-validation (Fig. Pseudodynamics extends previous models of T-cell maturation.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38911744429&p=1pl&v=1&x=H9RHEV0cIreI9VOqBCA4nQ
10.1038/nature14099,Biology_easy_576,"While previous research had identified the presence of feed forward loops in plant gene regulation, ""this study increases the scale enormously,"" said Bartley.",53.,"The third is a study like this one to improve lignocellulosic materials so you can get as much fuel as possible,"" she said. While previous research had identified the presence of feed forward loops in plant gene regulation, ""this study increases the scale enormously,"" said Bartley. That does not mean that scientists will necessarily be able to use this research to create plants with more easily digestible complex sugars in the very near future.","7) . First, dividing firefly luciferase activity by Renilla luciferase activity normalized the transformation efficiency of each infiltrated leaf sample. 53.",[1],Biology,train,1.0,news,http://www.scientificamerican.com/article/how-to-manipulate-plants-to-build-a-better-biofuel/
10.1126/sciadv.1600322,Biology_easy_577,"That scattered light can be detected in the form of a Raman spectrum, which serves almost as a fingerprint for every Raman-active irradiated system.","Besides the changes in HOMO-LUMO gaps, transmission values show significant differences at the p-to-p * transition of graphene (13, 30) (ca.","This technique can detect trace amounts of molecules in a solution at very low concentrations, some 10,000 times more diluted than can be seen by the naked eye. That scattered light can be detected in the form of a Raman spectrum, which serves almost as a fingerprint for every Raman-active irradiated system. That color is associated with a discrete energy.""","6 , B and C). Besides the changes in HOMO-LUMO gaps, transmission values show significant differences at the p-to-p * transition of graphene (13, 30) (ca. For instance, the transmission at the p-to-p * transition of PG increases from 89 to 90% after interacting with RhB molecules.",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/rV3AjT2fZfY/
10.1016/j.immuni.2010.06.001,Biology_easy_578,"The search can't end there, however.","(Mazmanian et al., 2005 .","The general population in industrialized countries is reflected in the healthy group concentration. The search can't end there, however. Despite the team's findings, they can't assign a causal link between the bacterium and RA without directly administering P. copri into people's bodies.","The gut microbiomes of humans and mice are broadly similar . (Mazmanian et al., 2005 . In more specific terms, gut-resident bacteria-sometimes even a single species-can have a strong influence on the emergence and/or maintenance of particular CD4 + T cell subsets.",[1],Biology,train,1.0,news,http://www.medicaldaily.com/gut-bacteria-may-be-possible-culprit-behind-rheumatoid-arthritis-262202
10.1126/science.1241680,Biology_easy_579,"It may be that manipulating the germinal center will be necessary to produce effective vaccines.""",S8B ; Movie S4).,"""We are slowly deciphering the rules governing antibody evolution in the germinal center,"" he says. ""This will help inform vaccine design, especially for rapidly mutating viruses like HIV. It may be that manipulating the germinal center will be necessary to produce effective vaccines.""","Before the boost, small numbers of GFP-OT-II cells were found scattered throughout the T cell zone, occasionally entering existing GCs for brief periods (Fig. S8B ; Movie S4). One day after immunization, GFP + cells could be seen proliferating in foci of T and B cells at the follicle/T zone border (Fig.",[1],Biology,train,1.0,news,http://www.sciencedaily.com/releases/2013/08/130809083831.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1136/jclinpath-2015-203546,Biology_easy_580,Proof that size DOES matter!,"The apparent resistance of P. mirabilis in the colony-forming assay was surprising, as other studies have demonstrated antibacterial activity of Manuka honey against this species.","Harrowing text messages reveal how...

Ready for the safari! Proof that size DOES matter! Blind hoarder is found to have unknowingly lived with...","Antibacterial activity is generally found to be highest in dark honey such as Manuka, whereas the suppression of mast cell activation was maximal with the relatively light-coloured eucalyptus honey. The apparent resistance of P. mirabilis in the colony-forming assay was surprising, as other studies have demonstrated antibacterial activity of Manuka honey against this species. 26 27 It arguably highlights the variability of raw honey, even from the same floral source, with storage time and conditions as likely factors.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/manuka-honey-could-be-used-on-medical-devices-to-stop-bacteria-building-up/
10.1038/s41467-017-01643-9,Biology_easy_581,The finding showed that the urban area was able to grow and thrive for several thousand years despite not having an actively flowing river nearby.,This result strongly suggests that the Sutlej River was the main source of fluvial sediment to the Ghaggar-Hakra palaeochannel.,"That means their civilization existed without a major active water source, something archaeologists did not believe was possible. The finding showed that the urban area was able to grow and thrive for several thousand years despite not having an actively flowing river nearby. ""The findings challenge our current understanding of how urbanization in many ancient civilizations began and grew in relation to natural resources,"" explained lead researcher Sanjeev Gupta, from the Department of Earth Science and Engineering at Imperial College London, Phys reported.","Notably, this peak is not dominant in the modern Yamuna, Ganges or Ghaggar river samples because the catchments of these rivers all lack prominent Palaeozoic granite bedrock 64 . This result strongly suggests that the Sutlej River was the main source of fluvial sediment to the Ghaggar-Hakra palaeochannel. The consistency of the zircon age distributions in fluvial sands taken from core samples traced from close to the Himalayan mountain front at SRH5 to Kalibangan, 300 km downstream, strengthens the case that these sands were deposited by the same sediment routing system.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=32649839624&p=1pl&v=1&x=SsPDKUrDqyunH6ix5JKBaA
10.1016/j.cell.2016.01.024,Biology_easy_582,This suggested that these breast milk sugars might promote healthy infant growth.,"This is not possible when transplanting intact, uncultured communities.","They found that sugars containing sialic acid, which has been implicated in brain development, were far more abundant in the breast milk of mothers with healthy compared with stunted babies. This suggested that these breast milk sugars might promote healthy infant growth. Given the difficulty of purifying large quantities of compounds from human breast milk, they turned instead to cow's milk, which contains sialylated sugars, but at 20-fold lower concentration than in breast milk.","Importantly, the culture collection in its entirety, or subsets of the collection, can be utilized to define the contribu- Figure S1 and Table S2. This is not possible when transplanting intact, uncultured communities. Sequencing 16S rRNA gene amplicons from the infant's uncultured fecal microbiota revealed that 77.8% of the bacterial composition detected in the intact community (97% ID OTUs, weighted by relative abundance) was represented in the culture collection ( Figure 2A ).",[1],Biology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/zW0mMT97ttg/
10.1073/pnas.0905235106,Biology_easy_583,Cargill clearly is getting on top of this trend.,"1 to FI/FO ϭ (RFEFM ϩ RFEFO)/2, where RFEFM is the same as in Fig.","If successful, the deal will make Cargill one of the top three aquaculture feed suppliers in the world. Cargill clearly is getting on top of this trend. First, the good news about this Big Ag aquaculture shift: As sources of protein, fish are way more efficient to raise than other leading sources of protein.","In contrast to overall protein needs, starch intake shows substantial variation ‡ The equation would change from that shown in Fig. 1 to FI/FO ϭ (RFEFM ϩ RFEFO)/2, where RFEFM is the same as in Fig. Indeed, farmed chickens now have a similar starch intake and overall efficiency in converting macronutrients to farmed weight gain as cold-blooded carp species.",[1],Biology,train,1.0,news,http://qz.com/481025/the-new-frontier-for-big-agriculture-is-aquaculture/
10.1098/rsos.140399,Biology_easy_584,"Like many other animals, these adorable rodent's aren't wired to think that bearing one's teeth is a sign of pleasure or affection.",One hamster reached criterion on the first day in Phase C (day 16).,"Like many other animals, these adorable rodent's aren't wired to think that bearing one's teeth is a sign of pleasure or affection. That's because, as it turns out, happy hamsters are optimist and willing to try new things. Predictably, the hamsters became fans of the sweet water, but avoided the bitter water all together.",Five hamsters reached criterion before the end of Phase B (day 15). One hamster reached criterion on the first day in Phase C (day 16). Hamsters correctly approached the sugar location on 84% of trials and the sugar control (C+) on 71% of trials.,[1],Biology,train,1.0,news,http://www.natureworldnews.com/articles/15898/20150802/hamsters-dont-smile-know-pet-happy.htm
10.1016/j.stemcr.2018.02.011,Biology_easy_586,"Asked what will happen if HHS determines the contracts did not meet those regulations, Collins said: ""I guess we'll have to cross that bridge when we get to it.""",The NSG-W host strain's more thorough immuno-depletion and/or use of quickly processed neonatal patient thymic explants may also have influenced our results.,"""That if something can be done with these tissues that might save somebody's life downstream, perhaps that's a better choice than discarding them."" Asked what will happen if HHS determines the contracts did not meet those regulations, Collins said: ""I guess we'll have to cross that bridge when we get to it."" Both pointed to adult stem cells, induced pluripotent stem cells, and organoids as viable alternatives to human fetal tissue.","In contrast, the robust circulating immune cells in the NeoThy are likely due to HSC co-injection coupled with human thymic education in vivo, as described below. The NSG-W host strain's more thorough immuno-depletion and/or use of quickly processed neonatal patient thymic explants may also have influenced our results. This contrasts with our ex vivo assay of T cell proliferation following TCR stimulation (Figures 3A and S2C) .",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37975181309&p=1pl&v=1&x=Uw0FXITkc3iaj8Qcnk9z9w
10.1038/s41467-018-06116-1,Biology_easy_587,"Professor Niimi stated, ""The multicolored Asian lady beetle (Harmonia axyridis) shows extraordinary intraspecific variation in wing colour patterns (>200 described colour forms), and seemed to be the best model to elucidate how insects have generated the diverse traits during evolution at the molecular level.",All procedures were rapidly performed to prevent diffusion of carotenoids.,"A similar result was also obtained in the seven-spot ladybird (Coccinella septempunctata), which lives all over the world. Professor Niimi stated, ""The multicolored Asian lady beetle (Harmonia axyridis) shows extraordinary intraspecific variation in wing colour patterns (>200 described colour forms), and seemed to be the best model to elucidate how insects have generated the diverse traits during evolution at the molecular level. In the genomic analyses of ladybird beetles, they found that the DNA sequences of the pannier gene in the multicolored Asian ladybird beetle was greater compared to other holometabolous insects including the seven-spot ladybird which shows a single color pattern.",Another important issue to clarify whether pannier is indeed the hotspot of morphological evolution in ladybird beetles is whether pannier is responsible for the remaining >20 minor colour patterns in H. axyridis. All procedures were rapidly performed to prevent diffusion of carotenoids. The PCR cycle number was 35 for all genes.,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37220693210&p=1pl&v=1&x=gksV4tLrg9tBiFMtfcu2RQ
10.1093/jmammal/gyw089,Biology_easy_589,"""This is exactly the opposite of what we need to be happening.""","In record #12, 2 individuals, an adult and a juvenile humpback dolphin, were observed near a floating dead calf.","""To lose a calf now, to lose another potential female that could add to the population, is devastating,"" Giles said. ""This is exactly the opposite of what we need to be happening."" There is evidence that the shortage of food has affected the clan's reproductive success, Balcomb said.","She was observed in her typical social group and foraging normally. In record #12, 2 individuals, an adult and a juvenile humpback dolphin, were observed near a floating dead calf. In record #13, a carcass of a humpback dolphin calf was observed floating in the Fitzroy River.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34741991783&p=1pl&v=1&x=ymowH-oQhWhN36jsZHEuSg
10.1038/s41588-019-0405-z,Biology_easy_590,"This latest advance, reported in the May issue of Nature Genetics, has already generated interesting leads, including the geographic origin of A. duranensis, one of the two ""parents"" of cultivated peanut.","Within genes, the B subgenome was enriched relative to the A subgenome for DNA sequences that corresponded to small RNAs ( Supplementary Fig.","This made it easier to identify structural features of the genomes and the genes residing on them. This latest advance, reported in the May issue of Nature Genetics, has already generated interesting leads, including the geographic origin of A. duranensis, one of the two ""parents"" of cultivated peanut. The team's genomic analysis of populations of plants that make up the wild peanut species pointed to a region in northern Argentina known as Rio Seco.","However, greater densities of DNA sequences that corresponded to uniquely mapping small RNAs were found in gene-rich chromosomal regions ( Supplementary  Fig. Within genes, the B subgenome was enriched relative to the A subgenome for DNA sequences that corresponded to small RNAs ( Supplementary Fig. As has been reported in other recent polyploids 27 , overall, the number of homeologous gene pairs with expression biased towards the A subgenome was not significantly different from the number biased towards the B subgenome (P = 0.2, two-sided binomial test; n = 3,648 and 3,759 for A and B, respectively).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39123190179&p=1pl&v=1&x=-eqGm6Vsy7elcg_neqfqCA
10.1038/s41586-019-1263-7,Biology_easy_591,"Targeted therapies could alter the behaviour of fibroblasts to reduce inflammation and tissue destruction in these two diseases without the need for long-term immunosuppression or joint replacements, say the scientists.",After assigning identities to all cell clusters (Fig.,"The research team shows, for the first time, that different types of fibroblasts -- the most common cells of connective tissue in animals -- are organised in different layers in the joint and are responsible for two very different forms of arthritis; osteoarthritis and rheumatoid arthritis. Targeted therapies could alter the behaviour of fibroblasts to reduce inflammation and tissue destruction in these two diseases without the need for long-term immunosuppression or joint replacements, say the scientists. ""From a research perspective this is exciting, but the clinical implications are also very important too.","Local deletion had the same effect on joint inflammation and bone damage with no effect observed in non-injected joints or following administration of diphtheria toxin in non-arthritic mice (Extended Data Fig. After assigning identities to all cell clusters (Fig. 3a, 5, Supplementary Table 1) , targeted reanalysis of the fibroblast populations on the basis of expression of known fibroblast markers revealed the existence of five distinct subgroups that we designate Extended Data Figs.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=39341208861&p=1pl&v=1&x=j1chv9wg5TQTIQ_7lHWmjw
10.1038/s41467-018-06861-3,Biology_easy_594,"By modifying brassinosteroid signaling researchers had so far achieved arabidopsis plants with increased drought ressistance, but due to the complex action of these hormones on plant growth, these plants were much smaller than the respective controls.",These results agree with the previously reported role of BR receptors in promoting root growth 41 .,"The study, published in the journal Nature Communications, is the first to find to find a strategy to increase hydric stress resistance without affecting overall plant growth. The study, published in the journal Nature Communications, is the first to find to find a strategy to increase hydric stress resistance without affecting overall plant growth. By modifying brassinosteroid signaling researchers had so far achieved arabidopsis plants with increased drought ressistance, but due to the complex action of these hormones on plant growth, these plants were much smaller than the respective controls.","1a , b) but also showed increased receptor levels in root vascular tissues 33 ( Supplementary Fig. These results agree with the previously reported role of BR receptors in promoting root growth 41 . A significantly lower level of relative root growth inhibition mediated by osmotic stress was observed in bri1 (27%), bri1brl1brl3 (28%), and quad (27%) mutants compared to the WT (39%; Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=37632584270&p=1pl&v=1&x=h_iy1mXIk2vo4MCfsBKzug
10.1126/scitranslmed.aaa5079,Biology_easy_595,"""We'd be very glad to see them here, if they want to come see us,"" he said.","CEBPA, CEBPB, and CEBPD have distinct functions .","Dr. Loughran, however, believes there needs to be additional study, hopefully in a larger trial, but the rarity of the disease makes recruiting subjects difficult. As such, he encourages patients with the disease to consider seeking treatment at the University of Virginia. ""We'd be very glad to see them here, if they want to come see us,"" he said.","6) . CEBPA, CEBPB, and CEBPD have distinct functions . As with the HIN-200 family, not all posttreatment samples up-regulated the same CEBP gene, but they all up-regulated at least one family member after treatment (Fig.",[1],Biology,train,1.0,news,http://www.oncologynurseadvisor.com/experimental-treatment-sends-deadly-leukemia-into-remission/article/425738/
10.1038/s41467-019-08383-y,Biology_easy_596,"All three anode samples showed higher lithium-ion capacity than current graphite or silicon-carbon anodes used in Li-ion batteries and superior conductivity--on the order of 100 to 1,000 times higher than conventional silicon anodes, when MXene is added.","The ultrahigh C/A of the Si/MXene electrodes can be attributed to the advanced electrode architecture; (1) the viscous nature of the MXene aqueous ink enables the formation of thick composite electrodes (thus high M Acitve /A) using a simple/scalable manufacturing process; (2) the high aspect ratio and metallic conductivity of MXene nanosheets endow the composite electrodes with mechanical robustness, high strength and excellent conductivity, facilitating fast electron transport; (3) the continuous MXene scaffold efficiently accommodates the volume change and stress induced by the Si lithiation/delithiation, and boosts the utilization of active materials.","They also have excellent mechanical strength, so silicon-MXene anodes are also quite durable up to 450 microns thickness."" All three anode samples showed higher lithium-ion capacity than current graphite or silicon-carbon anodes used in Li-ion batteries and superior conductivity--on the order of 100 to 1,000 times higher than conventional silicon anodes, when MXene is added. ""The continuous network of MXene nanosheets not only provides sufficient electrical conductivity and free space for accommodating the volume change but also well resolves the mechanical instability of Si,"" they write.","Even with a high M Active /A (~4 mg cm −2 ), graphite-Si/conductive-binder electrodes display a much lower C/A than the results reported here due to the excessive graphite content in the electrodes 47 . The ultrahigh C/A of the Si/MXene electrodes can be attributed to the advanced electrode architecture; (1) the viscous nature of the MXene aqueous ink enables the formation of thick composite electrodes (thus high M Acitve /A) using a simple/scalable manufacturing process; (2) the high aspect ratio and metallic conductivity of MXene nanosheets endow the composite electrodes with mechanical robustness, high strength and excellent conductivity, facilitating fast electron transport; (3) the continuous MXene scaffold efficiently accommodates the volume change and stress induced by the Si lithiation/delithiation, and boosts the utilization of active materials. Indeed, the thickness changes arẽ 34% in nSi/MX-C and~20% in Gr-Si/MX-C, suggesting 30 wt% of the MX-C nanosheet network has effectively accommodated the volume change induced by 70 wt% of Si particles (Supplementary Fig.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38601608102&p=1pl&v=1&x=Se42J3Exn5t7Awr_ViZtlA
10.1038/s41467-018-04079-x,Biology_easy_598,"This could help us explore space and track satellites, and even keep the world's time zones in sync.",From the measured profile shown in Fig.,"This could help us explore space and track satellites, and even keep the world's time zones in sync. ""I would call lutetium top in its class."" With more 'ticks' or oscillations in each second, time can be measured with greater and greater precision.","• , the light shift measured as a function of beam position determines the spatial profile of the laser beam. From the measured profile shown in Fig. 2b , a peak intensity relative to the incident optical power of I max /P = 36.8 (8) mm −2 can be inferred (see Methods).",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34184284121&p=1pl&v=1&x=Gq5Z5hRlroW5wIifqWlTzA
10.1038/s41467-018-07690-0,Biology_easy_599,They are much cooler than the surrounding areas and are highly magnetized.,These localized inflows effectively reduce the latitudinal separation between opposite polarities and allow less flux to reach the polar region.,"They are much cooler than the surrounding areas and are highly magnetized. The tadpole discovery adds a third possibility to the mix. Scientists found the tadpoles were made up entirely of plasma--the fourth state of matter, consisting of electrically conducting material made up of charged particles.",The quantity T n accounts for the variation of tilt angle with cycle strength 57 . These localized inflows effectively reduce the latitudinal separation between opposite polarities and allow less flux to reach the polar region. The initial radial magnetic field associated with the BMR is,[1],Biology,train,1.0,news,http://ct.moreover.com/?a=38589987783&p=1pl&v=1&x=9laG3ereFul8pv27_aEYIg
10.1098/rstb.2010.0340,Biology_easy_600,"""As bivalves open easily after cooking, this does suggest that the mollusks at Trinil weren't cooked,"" says Szabo.","They differ from their approximately 120 -70 ka antecedents in that they take the form of hundreds of discrete types, identifying regional patterns .","That requires a certain degree of dexterity and knowhow, so Homo erectus became the most likely culprit. ""As bivalves open easily after cooking, this does suggest that the mollusks at Trinil weren't cooked,"" says Szabo. There is another possible reason Homo erectus might have been scraping out mollusk shells.","One of the latter , and reappeared almost everywhere in Africa and Eurasia after this time span; approximately 40 ka old beads from Europe are associated with both Neanderthals and AMH . They differ from their approximately 120 -70 ka antecedents in that they take the form of hundreds of discrete types, identifying regional patterns . As with formal bone tools (see above), the minimalistic consensual interpretation of personal ornament use by Neanderthals (figure 1x) is that they were fully able to incorporate new categories of symbolic items in their own culture.",[1],Biology,train,1.0,news,http://www.smithsonianmag.com/science-nature/oldest-engraving-shell-tools-zigzags-art-java-indonesia-humans-180953522/
10.1126/scitranslmed.aac8577,Biology_easy_601,aEURoeI would say the spring and the fall are the better months.,The mean serum MCP-1 level of 16-week-old Npt2b −/− mice is shown for comparison.,"If it gets too cold I canaEUR(tm)t breathe,aEUR says Falco. aEURoeI would say the spring and the fall are the better months. ItaEUR(tm)s very hard to explain whataEUR(tm)s wrong.","Changes in serum MCP-1 levels closely paralleled the radiographic and histologic course after adoptive microlith transfer, more than tripling from baseline to peak inflammation at 7 days, and returning to near baseline at 1 month (Fig. The mean serum MCP-1 level of 16-week-old Npt2b −/− mice is shown for comparison. Therapeutic lavage reduces pulmonary opacities and microlith burden Infrared spectroscopy revealed that alveolar microliths isolated from Npt2b −/− mice were composed of calcium phosphate, predominantly hydroxyapatite.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/pulmonary-alveolar-microlithiasis-mouse-model-offers-new-insights-into-rare-lung-disease/
10.1038/s41467-017-01823-7,Biology_easy_603,Certain devices using Snapdragon's Quick Charge technology can receive five hours of battery life from a five minute charge.,"Overall, the unique hierarchical structure of GB enables its uniform coating over micrometersize NCM powder at the minimal content ( Fig.","""The key is who can commercialise the technology first. It won't be easy to apply the minute processing technology for large-scale production of high-quality, electronics-grade graphene."" Certain devices using Snapdragon's Quick Charge technology can receive five hours of battery life from a five minute charge.","Importantly, even 1 wt% addition of GB improved the conductivity of NCM powder significantly when tested in a pelletized form; pelletized pristine NCM and GB-NCM exhibited conductivity values of 1.13 × 10 −3 and 9.72 × 10 −2 s cm −1 , respectively. Overall, the unique hierarchical structure of GB enables its uniform coating over micrometersize NCM powder at the minimal content ( Fig. 3k ) and supplements the relatively low conductivity of NCM.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=32630328216&p=1pl&v=1&x=6ZRZOGhILIwtAVP27UPNMg
10.1038/s41467-018-05153-0,Biology_easy_604,"At some threshold level of disorder, long-range ordered CDW disappears abruptly, and superconducting transition temperature is abruptly reduced as well.",The substantial decrease of T c and exponential-like saturation of ∆λ can be explained with multiband s-wave type superconducting gap with some amount of interband coupling.,"""As CDW is suppressed or disrupted, superconductivity is grabbing the electrons needed to form Cooper's pairs, which form superconducting condensate."" At some threshold level of disorder, long-range ordered CDW disappears abruptly, and superconducting transition temperature is abruptly reduced as well. ""It is very important to understand the factors that influence superconductivity, in particular its critical temperature,"" said Prozorov.","All the T c suppressions from these three samples (P1, P2, P3) are summarized in Fig. The substantial decrease of T c and exponential-like saturation of ∆λ can be explained with multiband s-wave type superconducting gap with some amount of interband coupling. Upon initial irradiation up to 1.0 C cm −2 , an anticorrelation of T CDW and T c was observed, which is most naturally interpreted in terms of strong competition between the superconducting and CDW phases.",[1],Biology,train,1.0,news,http://ct.moreover.com/?a=34641425109&p=1pl&v=1&x=lbE2fn9BEKTbMOm0eBc60A
10.1007/s11056-016-9561-5,Biology_easy_605,Their enthusiasm and the wonderful example of this model inspired Steiner in the late 1990s to offer his services to the organization as a volunteer science adviser.,"Considering that the most resistant B 3 F 2 s have breeding values closer to C. mollissima than to C. dentata within pollen clouds from partially selected plantations, the maximum resistance of the B 3 F 3 progeny is expected to approach the mean resistance of C. mollissima upon completion of selection at B 3 F 2 .","""But he did not reckon on the ability of a nonprofit organization like the American Chestnut Foundation to accomplish a 'lost-cause' conservation task through the power of thousands of volunteer citizen-scientists and philanthropic supporters."" Their enthusiasm and the wonderful example of this model inspired Steiner in the late 1990s to offer his services to the organization as a volunteer science adviser. And he is not alone.","Actual gains may be less depending upon the level of genotype by environment interaction. Considering that the most resistant B 3 F 2 s have breeding values closer to C. mollissima than to C. dentata within pollen clouds from partially selected plantations, the maximum resistance of the B 3 F 3 progeny is expected to approach the mean resistance of C. mollissima upon completion of selection at B 3 F 2 . Restoration trials composed of B 3 F 3 progeny from selected B 3 F 2 parents will determine whether resistance after selection at B 3 F 2 is sufficient to generate reproductive, self-sustaining populations in the forest.",[1],Biology,train,1.0,news,http://www.futurity.org/american-chestnut-more-time-1432472/
10.1038/ncb2578,Biology_easy_606,"""It's likely this mechanism is related to diseases such as type 2 diabetes.","These results suggest that under basal conditions, GRP94 retains WFS1 in the ER and when stimulated with glucose, GRP94 releases WFS1 allowing WFS1 to escape the ER.","While WS is a rare condition, affecting only about 1 in 500,000 people, Urano says the findings also may be important in the treatment of more common disorders. ""It's likely this mechanism is related to diseases such as type 2 diabetes. If a complete absence of the WFS1 protein causes WS, perhaps a partial impairment leads to something milder, like diabetes.""","5b ), but reforms in the presence of Tg treatment (Fig. These results suggest that under basal conditions, GRP94 retains WFS1 in the ER and when stimulated with glucose, GRP94 releases WFS1 allowing WFS1 to escape the ER. In the presence of ER stress, the GRP94-WFS1 complex reforms, presumably to maintain WFS1 in the ER to fulfil its function in ameliorating ER stress; however, this leads to an overall reduction in β-cell function as seen in Fig.",[1],Biology,train,1.0,news,http://www.redorbit.com/news/health/1112696131/genetic-mutation-linked-to-rare-diabetes-091812/
10.1038/s41467-018-06280-4,Biology_easy_607,"The study found that that while smoky air makes it harder for these clouds to grow, pollution energizes their growth, but only if the pollution isn't heavy.",3 display similar characteristics.,"The study found that that while smoky air makes it harder for these clouds to grow, pollution energizes their growth, but only if the pollution isn't heavy. Extreme pollution is likely to shut down cloud growth. Even the same type of aerosol may have different effects at different altitudes in the atmosphere or at different concentrations of particles.","This behavior was attributed to the enhanced aerosol that reduces the amount of surface illumination. 3 display similar characteristics. However, we find that clouds in smoke, polluted continental and certain dust environments behave differently, suggesting that cloud heights are also sensitive to the aerosol type.",[1],Biology,train,1.0,news,http://earthsky.org/earth/study-aerosals-particles-pollution-smoke-thunderclouds
10.1038/nm.4153,Biology_easy_608,"The team showed that the drug, GKT137831, was also effective in reducing inflammasome activation in mice, including in the pneumonia model.","8b,c) , relative to that in control cells.","Without this NOX-4-dependent boost in fat breakdown, the inflammatory response was blunted. The team showed that the drug, GKT137831, was also effective in reducing inflammasome activation in mice, including in the pneumonia model. ""Since this drug is already in phase 2 clinical trials, we think it is a good candidate for additional research as a treatment for patients with metabolic inflammation and infectious disease as well,"" said Dr. Choi, who is also physician-in-chief at NewYork-Presbyterian/Weill Cornell Medical Center.","8a ) and secretion of IL-1β, IL-18 and TNF-α in LPS-primed WT peritoneal macrophages in response to nigericin and ATP (Supplementary Fig. 8b,c) , relative to that in control cells. Notably, treatment of LPS-primed primary human macrophages with GKT137831 or VAS-2870 resulted in lower caspase-1 activation, IL-1β cleavage (Fig.",[1],Biology,train,1.0,news,http://healthmedicinet.com/news/enzyme-links-metabolic-state-to-inflammatory-response-to-infection/
10.1093/molbev/msu185,Biology_easy_609,"In contrast, HSV-1 has been present in humans for far longer.","5C ), likely caused by low precision point estimates of dN/dS.","In the end, the researchers found that HSV-2 was far more genetically similar to the herpes virus found in chimpanzees. This seemed to indicate that humans must have acquired it from an ancestor of modern chimps about 1.6 million years ago, prior to the rise of modern humans about 200,000 years ago. In contrast, HSV-1 has been present in humans for far longer.","One of the length expansions (involving a short terminal branch leading to an HVP-2 isolate) appears to be an outlier ( fig. 5C ), likely caused by low precision point estimates of dN/dS. However, when we used the original (GTR + À 4 ) branch length instead of the expanded length for this branch in our subsequent analyses, the hypothesis testing results and tMRCA inference remained unaffected (not shown).",[1],Biology,train,1.0,news,http://www.scienceworldreport.com/articles/15347/20140611/evolutionary-origins-herpes-virus-infected-humans-before-human.htm
10.1177/0141076814565942,Psychology_0,"Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years.""","Results: With a total of 4986 ASD cases, our study showed that regardless of cultural background circumcised boys were more likely than intact boys to develop ASD before age 10 years (HR ¼ 1.46; 95% CI: 1.11-1.93).","Nearly 5,000 cases of ASD were diagnosed during that time. Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years."" What's more, ""risk was particularly high for infantile autism before age 5 years.""","Results: With a total of 4986 ASD cases, our study showed that regardless of cultural background circumcised boys were more likely than intact boys to develop ASD before age 10 years (HR ¼ 1.46; 95% CI: 1.11-1.93). Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13). Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96).","[5.0, 4.0, 4.0, 4.0, 5.0]",Psychology,train,4.4,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1177/0141076814565942,Psychology_1,"What's more, ""risk was particularly high for infantile autism before age 5 years.""",Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13).,"Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years."" What's more, ""risk was particularly high for infantile autism before age 5 years."" That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces.","Results: With a total of 4986 ASD cases, our study showed that regardless of cultural background circumcised boys were more likely than intact boys to develop ASD before age 10 years (HR ¼ 1.46; 95% CI: 1.11-1.93). Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13). Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96).","[5.0, 5.0, 5.0]",Psychology,train,5.0,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1177/0141076814565942,Psychology_10,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.",We confirmed our hypothesis that boys who undergo ritual circumcision may run a greater risk of developing ASD.,"The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","Associations with asthma were consistently inconspicuous (HR ¼ 0.96; 95% CI: 0.84-1.10). We confirmed our hypothesis that boys who undergo ritual circumcision may run a greater risk of developing ASD. This finding, and the unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families, need attention, particularly because data limitations most likely rendered our HR estimates conservative.","[4.0, 5.0, 4.0, 4.0, 3.0]",Psychology,train,4.0,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1001/jamapsychiatry.2018.1941,Psychology_100,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,1D involved in both poor sleep quality and depressive problems significantly mediated the relationship between the PSQI score and depressive problems score (Fig.,"In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","The mean strength of the 39 significant functional connectivities shown in Fig. 1D involved in both poor sleep quality and depressive problems significantly mediated the relationship between the PSQI score and depressive problems score (Fig. 2D , path AB) (4.8% of the total effect size, = 0.0139; p = 2.1×10 -5 ; 95% CI, 0.01 to 0.03).","[2.0, 4.0, 5.0, 4.0, 5.0]",Psychology,train,4.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1177/0141076814565942,Psychology_101,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.","As with the missing circumcisions performed by religious circumcisers, such non-differential exposure misclassification will most likely produce conservative estimates of any real difference in ASD risk between circumcised and intact boys.","The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","Our HR estimates for ASD are therefore most likely conservative. As with the missing circumcisions performed by religious circumcisers, such non-differential exposure misclassification will most likely produce conservative estimates of any real difference in ASD risk between circumcised and intact boys. Reassuringly, our robustness analysis in which we restricted the observation period to 1994-2003, when ritual circumcisions and ASD outcomes were covered, revealed a stronger association of ritual circumcision with ASD risk (HR ¼ 1.62) than in the main analysis (HR ¼ 1.46).","[2.0, 4.0, 2.0, 3.0]",Psychology,train,2.75,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1016/j.jpeds.2017.10.028,Psychology_102,"In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children.","Notably, this latter finding refers only to acts of violence and not frequency or severity, which is important, given research showing that female subjects may suffer more long-term negative physical and psychosocial consequences of teen dating violence.","Of the 758 young adults recruited for the study, 61 percent were female. In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship.","Third, consistent with extant literature, female subjects were more likely to perpetrate teen dating violence than their male counterparts. Notably, this latter finding refers only to acts of violence and not frequency or severity, which is important, given research showing that female subjects may suffer more long-term negative physical and psychosocial consequences of teen dating violence. Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence.","[3.0, 3.0, 3.0, 1.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1016/j.jpeds.2017.10.028,Psychology_104,"""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult.""",One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence.,"That held true even after the researchers took into account the person's age, gender, parents' education and any history of child physical abuse. ""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult."" It's not that big a stretch to connect the two, he added.","9 These factors cut across various domains including affective (eg, emotion dysregulation, psychiatric disorder), cognitive (eg, attitudes toward women, beliefs about violence), demographic (eg, age, race, sex, sexual orientation, socioeconomic status), interpersonal (eg, relationship satisfaction, problem solving skills), contextual (eg, availability of weapon, drug/alcohol use), as well as distal factors (eg, history of child abuse, exposure to family violence). One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence. Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth.","[5.0, 4.0, 4.0, 5.0, 5.0]",Psychology,train,4.6,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1093/chemse/bjt066,Psychology_106,"However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive.","Because half of the odors had a positive food labels and negative nonfood labels, it could be argued that the positive food labels in themselves led to the increase in the edibility ratings of these odors.","This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process. However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive. ""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu.","A limitation of the present study is that the design is not balanced in terms of label edibility and therefore could bias our findings of the impact of labels on odor perception. Because half of the odors had a positive food labels and negative nonfood labels, it could be argued that the positive food labels in themselves led to the increase in the edibility ratings of these odors. Despite this limitation, we do find this to be true even for the 2 odors with both positive and negative nonfood labels, which supports that we found an effect of edibility on labeled manipulated odors.","[2.0, 3.0, 2.0, 3.0]",Psychology,train,2.5,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1016/j.jpeds.2017.10.028,Psychology_107,"Although the research could not prove that one directly caused the other, it serves as yet another piece of data to suggest that corporal punishment could do more harm than good.","The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence.","Although the research could not prove that one directly caused the other, it serves as yet another piece of data to suggest that corporal punishment could do more harm than good. Of the 758 young adults recruited for the study, 61 percent were female. In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children.","Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence. Furthermore, variables known to relate to dating violence were controlled for, which highlights the importance of the unique impact of corporal punishment on perpetration of dating violence and addresses longstanding criticisms regarding a potentially confounding link between corporal punishment and poor outcomes.","[3.0, 1.0, 1.0, 1.0, 4.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1111/cdev.12250,Psychology_108,"The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers.","The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time. If the trend lines continued past age 15, you'd expect so-called cool-kid behavior to be less associated with popularity as people get older -- and that's exactly what happened.","Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular""). The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers. It remains possible, for example, that teens engaging in pseudomature behavior might possibly maintain a degree of status-based popularity (i.e., perceptions by others that they are members of the ""popular"" group) even if preference-based measures (such as used in this study, indicating other teens' actual desire to spend time with study participants) show declining social preference over time for teens engaging in pseudomature behavior.","[3.0, 3.0, 1.0, 3.0]",Psychology,train,2.5,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1177/0141076814565942,Psychology_109,They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD.,"Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys.","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) . Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys. Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys.","[2.0, 2.0, 4.0, 3.0]",Psychology,train,2.75,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1177/0141076814565942,Psychology_11,The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation.","The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. While it is unacceptable today to circumcise boys without proper pain relief, there is no way to eliminate the pain completely, the researchers said, adding that some boys will endure a lot of pain.","More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism. To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation. As expected, risk of asthma was independent of the boys' foreskin status, which is in accordance with prior findings for asthma in the first years of life.","[1.0, 3.0, 5.0, 4.0]",Psychology,train,4.0,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1016/j.jpeds.2017.10.028,Psychology_110,"""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult.""","Second, in contrast to past research, no differences in corporal punishment were found when stratified by demographic characteristics.","That held true even after the researchers took into account the person's age, gender, parents' education and any history of child physical abuse. ""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult."" It's not that big a stretch to connect the two, he added.","First, more than one-half (68%) of participants in this sample reported experiencing corporal punishment as children. Second, in contrast to past research, no differences in corporal punishment were found when stratified by demographic characteristics. Third, consistent with extant literature, female subjects were more likely to perpetrate teen dating violence than their male counterparts.","[2.0, 4.0, 2.0, 2.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1093/jcr/ucw012,Psychology_111,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","Participants in the demographically targeted condition recognized an implied label marginally more than those in the nontargeted condition (F(1, 185) ¼ 3.06, p ¼ .08, g 2 ¼ .02). Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions. An ANOVA on purchase intentions for the restaurant Groupon revealed a significant difference between the conditions (F(2, 185) ¼ 3.81, p < .05, g 2 ¼ .04).","[4.0, 4.0, 2.0, 3.0, 3.0]",Psychology,train,3.2,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1001/jamapsychiatry.2018.1941,Psychology_112,"While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants.","Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","We note that the causal relations between sleep and depression is an important topic that deserves much further investigation. Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants. A strength of this investigation is that the effects are likely to be very robust, given the large sample of participants with resting-state fMRI and the cross-validation with the UK Biobank data set with a sample of 8718 participants in one of its first uses of resting-state fMRI data.","[2.0, 5.0, 4.0, 5.0]",Psychology,train,5.0,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1111/cdep.12038,Psychology_113,"Moreover, for both boys and girls, she said, ""We found [spanking] linked to more aggression, more delinquent behavior, more mental health problems, worse relationships with parents, and putting the children at higher risk for physical abuse from their parents.""","Rather, spanking predicted increases in children's aggression over and above initial levels.","Although spanking is traditionally supposed to teach a lesson to correct bad behavior, children who were spanked were neither more compliant nor better behaved. Moreover, for both boys and girls, she said, ""We found [spanking] linked to more aggression, more delinquent behavior, more mental health problems, worse relationships with parents, and putting the children at higher risk for physical abuse from their parents."" We see consistently that the more children are spanked, the more behavioral problems they have in the years ahead.""","In these studies, although children's aggressive behavior often elicited more spanking over time, this effect did not entirely explain the association between spanking and children's aggression. Rather, spanking predicted increases in children's aggression over and above initial levels. Spanking consistently predicted increases in children's aggression over time, regardless of how aggressive children were when the spanking occurred.","[4.0, 4.0, 4.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=37496711489&p=1pl&v=1&x=NWsoYnhIAFQ7txCZZJ6ciQ
10.1007/s13524-014-0321-x,Psychology_114,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births.","For first births, parents' happiness trajectories increase sharply before and around the birth and then settle close to pre-birth levels, which is the same result shown earlier in .","The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births. The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.","We control for the influence of previous births; without these, the baseline level estimated as four to five years before the birth (separately for each parity) would be influenced by the previous births. For first births, parents' happiness trajectories increase sharply before and around the birth and then settle close to pre-birth levels, which is the same result shown earlier in . Standard errors are estimated using robust methods that account for the clustering of data within individuals.","[1.0, 3.0, 3.0, 3.0, 3.0]",Psychology,train,2.6,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0141076814565942,Psychology_115,The researchers say that the pain associated with circumcision in very young babies is likely to be more severe during the operation and post-operatively.,", , 4 Thus, while most boys presumably experience mild to moderate levels of pain and discomfort during and after the operation, some boys will endure strongly painful circumcisions.","Risk was particularly high for infantile autism before the age of five, at least in epidemiology. The researchers say that the pain associated with circumcision in very young babies is likely to be more severe during the operation and post-operatively. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""","Older children whose foreskins have already spontaneously separated from the glans will only experience the pain associated with the foreskin incision. , , 4 Thus, while most boys presumably experience mild to moderate levels of pain and discomfort during and after the operation, some boys will endure strongly painful circumcisions. Neonatally circumcised boys in Canada exhibited significantly more signs of discomfort during routine vaccinations -6 months later than boys who were left intact, showing that early life trauma may alter a child's future handling of pain.","[4.0, 4.0, 2.0, 2.0]",Psychology,train,3.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1111/cdev.12250,Psychology_116,"The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote.","Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence.","In fact, just the opposite happened. The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","5. Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence. Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information.","[3.0, 2.0, 3.0, 4.0]",Psychology,train,3.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1007/s13524-014-0321-x,Psychology_117,Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility.,"Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility.","Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources. Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.","Decreasing gains in subjective well-being at higher birth orders may inhibit people from moving to parity three. Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility. In addition to the type of social learning about the optimal timing and number of children to have , fertility decisions may be affected by observing the subjective experiences of others.","[4.0, 2.0, 1.0, 2.0, 2.0]",Psychology,train,2.2,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1093/jcr/ucw012,Psychology_118,One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.,"We therefore predict that when the label implied by a behaviorally targeted advertisement is plausibly connected to the consumer's prior behavior (i.e., the targeting is at least moderately accurate), consumers perceive that the marketer has labeled them correctly and respond accordingly, altering their self-perceptions and hence behavior to be consistent with the identity implied by the ad.","For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","However, if there is a plausible connection between the label and past behavior, the label is accepted and consumers adjust self-perceptions and behavior in line with that label. We therefore predict that when the label implied by a behaviorally targeted advertisement is plausibly connected to the consumer's prior behavior (i.e., the targeting is at least moderately accurate), consumers perceive that the marketer has labeled them correctly and respond accordingly, altering their self-perceptions and hence behavior to be consistent with the identity implied by the ad. In contrast, when the label is unconnected with their prior behavior (i.e., targeting is inaccurate), consumers will not accept the implied label and will not adjust their self-perceptions and behavior.","[5.0, 1.0, 4.0, 4.0, 4.0]",Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1093/jcr/ucw012,Psychology_119,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions.","""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","Participants in the demographically targeted condition recognized an implied label marginally more than those in the nontargeted condition (F(1, 185) ¼ 3.06, p ¼ .08, g 2 ¼ .02). Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions. An ANOVA on purchase intentions for the restaurant Groupon revealed a significant difference between the conditions (F(2, 185) ¼ 3.81, p < .05, g 2 ¼ .04).","[4.0, 4.0, 3.0, 4.0]",Psychology,train,3.75,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1007/s13524-014-0321-x,Psychology_12,"Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents.","Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline.","Those who have children at an older age or who are more educated have a particularly positive response to a first birth. Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.","Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below. Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline. A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain.","[4.0, 4.0, 4.0, 3.0]",Psychology,train,3.75,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1505114112,Psychology_120,Electrode recordings at the start of the study and three years later revealed that the music group showed more rapid maturation in the brain's response to sound.,"Synaptic density follows a similar developmental trajectory, increasing in early childhood and subsequently declining during adolescence (2-5).","""Although learning to play music does not teach skills that seem directly relevant to most careers, the results suggest that music may engender what educators refer to as 'learning to learn.'"" Electrode recordings at the start of the study and three years later revealed that the music group showed more rapid maturation in the brain's response to sound. They also demonstrated prolonged heightened brain sensitivity to sound details.","Response consistency peaks in childhood (∼8-11 y of age), declining steadily until young adulthood ; we show that this adolescent decline is mitigated by in-school music lessons. Synaptic density follows a similar developmental trajectory, increasing in early childhood and subsequently declining during adolescence (2-5). Consistent with previous cross-sectional studies showing enhanced response consistency in musicians and in participants using assistive listening devices (75), the music training group maintained a higher level of response consistency between years 1 and 4.","[3.0, 4.0, 1.0, 3.0, 1.0]",Psychology,train,3.0,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1136/bmjsem-2017-000261,Psychology_121,"A spike in cortisol in athletesa saliva before competition, they wrote, would support the idea that apsychosocial stressorsa can have as strong a biological effect as actual danger.",These findings further support the presence of anticipatory stress response in athletes before sport competition.,"This is not, after all, the first time people have reported that watching the English national team play was enough to precipitate a full-fledged biological stress response. A spike in cortisol in athletesa saliva before competition, they wrote, would support the idea that apsychosocial stressorsa can have as strong a biological effect as actual danger. They found that there was a asignificant anticipatory cortisol response before competition,a although the spikes werenat as strong as those seen before other intense events, like skydiving.","The combined results identified the presence of a significant anticipatory cortisol response before competition (g=0.85) where the anticipatory cortisol response is significantly greater when assessed closer to the start of competition. These findings further support the presence of anticipatory stress response in athletes before sport competition. However, we identified large heterogeneity between effect sizes from individual studies where our analysis of moderating variables (eg, gender, type of sport) could not fully explain this large heterogeneity.","[4.0, 4.0, 4.0, 2.0, 4.0]",Psychology,train,3.6,news,http://ct.moreover.com/?a=34474732617&p=1pl&v=1&x=pcdQFFmMveKF7UrJyJtzvg
10.1038/s41598-017-18902-w,Psychology_122,"Next, the researchers aim to conduct movement assessments on more people, including more research on the parents of children with autism to better understand the connection between lower parental scores on the movement assessment and their children's risk for autism.",Our results have thus unraveled a significant correlation between movement and other aspects of Autism development.,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism. Next, the researchers aim to conduct movement assessments on more people, including more research on the parents of children with autism to better understand the connection between lower parental scores on the movement assessment and their children's risk for autism.","This result provides added evidence about the independent reliability of using the R-parameter classification. Our results have thus unraveled a significant correlation between movement and other aspects of Autism development. the noise level present in the motor output, may provide an underlying mechanism contributing to the variable motion disturbances present in the spectrum, as well as in other autistic symptons.","[3.0, 4.0, 2.0, 3.0, 3.0]",Psychology,train,3.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1111/cdev.12250,Psychology_123,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""",This finding indicates just how potentially important this social pathway toward future difficulties may be in identifying individuals at risk for long-term problems with alcohol and substance use.,"By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time . This finding indicates just how potentially important this social pathway toward future difficulties may be in identifying individuals at risk for long-term problems with alcohol and substance use. These findings also suggest that the constellation of pseudomature behaviors examined was capturing something other than a simple propensity toward deviant behavior.","[5.0, 4.0, 3.0, 1.0, 5.0]",Psychology,train,4.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1177/0141076814565942,Psychology_125,"The study discovered that, regardless of their cultural background, circumcised boys could be at greater risk of developing the condition.","Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys.","The study discovered that, regardless of their cultural background, circumcised boys could be at greater risk of developing the condition. While these days, it is considered unacceptable medical practice to perform a circumcision without proper pain relief, none of the most common interventions used to reduce such pain is capable of completely eliminating it, the study authors said. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences,"" he added.","Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys. Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys. Overall, the risk of hyperkinetic disorder was not elevated among ritually circumcised boys in the first 0-4 years of life (HR ¼ 0.99; 95% CI: 0.43-2.29) or in the 5-to 9-year age group (HR ¼ 1.27; 95% CI: 0.95-1.71) ( Table 2) .","[4.0, 4.0, 4.0, 2.0]",Psychology,train,3.5,news,http://www.redorbit.com/news/health/1113311836/does-circumcision-increase-the-risk-of-autism-011115/
10.1111/cdev.12250,Psychology_126,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Alternatively, these teens may actually be later selecting partners as adults who are similar to themselves in terms of status-seeking behavior, and may thus find that their partners actually are ending relationships with them due to status concerns.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","These teens may then be likely to perceive social status as a primary reason for the formation or dissolution of important relationships (e.g., romantic relationships) going forward, whether or not this is actually the case. Alternatively, these teens may actually be later selecting partners as adults who are similar to themselves in terms of status-seeking behavior, and may thus find that their partners actually are ending relationships with them due to status concerns. In either case, these findings make clear that the status-seeking aspect of early adolescent pseudomature behavior displays long-term continuity that extends into a new and important relationship domain even across a span of nearly a decade.","[1.0, 2.0, 1.0]",Psychology,train,1.3333333333333333,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1001/jamapsychiatry.2018.1941,Psychology_127,The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep.,"Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis.","Results showed that 162 functional connectivity links in the brain were connected with our ability (or lack of) to get some shut-eye; of these, 39 were also linked to depressive problems a such as low self-esteem, low mood, and a lack of motivation. The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""","We note that there is a strong association between depression and poor sleep, in that the correlation found in this study between the Depressive Problems score and PSQI score was high (r = 0.371, P <1.0×10 −10 , Figure 1B) ; however, this does not address the directionality of the association, which could be in both directions. Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis. We note that the causal relations between sleep and depression is an important topic that deserves much further investigation.","[5.0, 3.0, 4.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1001/jamapsychiatry.2013.4081,Psychology_128,"Overall, the researchers found, children born to parents younger than 25 and older than 29 were more likely to be diagnosed and treated for some mental illness or developmental challenge--even when they controlled for a family history of such diagnoses.","[17] Regardless of the precise nature of the mechanisms linking parental age and the risk for mental disorders in the offspring, an informed public health debate on these matters requires a solid empirical foundation.","The age at which you become parents could affect your kids' mental health. Overall, the researchers found, children born to parents younger than 25 and older than 29 were more likely to be diagnosed and treated for some mental illness or developmental challenge--even when they controlled for a family history of such diagnoses. Outside the bounds of that narrow age range, risks for various disorders gradually picked up.","14 Risk factors that are associated with teenaged parenthood and suboptimal outcomes in the offspring are often highly intercorrelated and socially patterned. [17] Regardless of the precise nature of the mechanisms linking parental age and the risk for mental disorders in the offspring, an informed public health debate on these matters requires a solid empirical foundation. The findings were therefore based entirely on incident cases diagnosed according to the more operational ICD-10-DCR classification system (during a period when inpatient and outpatient information was used), except that the ICD-8 classification and the first year of the operation of the ICD-10-DCR classification was used to exclude persons with a diagnosis before 1995.","[3.0, 4.0, 1.0, 2.0, 1.0]",Psychology,train,2.2,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1016/j.bodyim.2016.09.005,Psychology_129,This was not the first time researchers claim Barbie dolls affect young girls' body image.,"However, the results of the study did not support these conjectures as the different types of Barbie exposure produced no significant differences in thin-ideal internalisation, body esteem, or body dissatisfaction scores.","""If girls already have Barbies then parents should encourage them to do more than just make them look pretty,"" Tiggerman said, according to Daily Mail. This was not the first time researchers claim Barbie dolls affect young girls' body image. This research has drawn up similar conclusions the doll is giving children an unrealistic image that being slim is better.","Such research could also provide insight into the reason results differed from those of . However, the results of the study did not support these conjectures as the different types of Barbie exposure produced no significant differences in thin-ideal internalisation, body esteem, or body dissatisfaction scores. It is possible that girls in this age group may already be so familiar with Barbie's figure from previous experience that any exposure to Barbie triggers associations with previous exposure (in print, observation, or active play) and elicits Barbie's thin-ideal messages.","[4.0, 1.0, 2.0, 1.0]",Psychology,train,1.0,news,http://www.parentherald.com/articles/97873/20170130/barbie-dolls-harm-little-girls-body-image-experts-advise-parents.htm
10.1001/jamapsychiatry.2018.1941,Psychology_13,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,"Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig.","In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","In the reverse direction, only 2 links significantly mediated effects of sleep quality on depressive problems with FDR correction. Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig. S4 ) than for the effect in the opposite direction described above.","[2.0, 3.0, 4.0]",Psychology,train,3.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1001/jamapsychiatry.2013.4081,Psychology_130,"While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29.","In contrast, paternal age showed a U-shaped relationship, with the offspring of teenaged fathers having a 28% increased risk for a psychiatric disorder (IRR, 1.28 [95% CI, 1.24-1.32]), whereas the offspring of the fathers 45 years or older had a 34% increased risk (1.34 [1.30-1.39]).","Results for older parents were varied as well. While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29. The study adds to a growing body of research focused on the specific effects of parental age.","No significantly increased risk for the offspring of older mothers was found. In contrast, paternal age showed a U-shaped relationship, with the offspring of teenaged fathers having a 28% increased risk for a psychiatric disorder (IRR, 1.28 [95% CI, 1.24-1.32]), whereas the offspring of the fathers 45 years or older had a 34% increased risk (1.34 [1.30-1.39]). Figure 1 shows the relationship between maternal and paternal ages and the risk for any mental disorder when not adjusted and when adjusted for age of the other parent.","[5.0, 5.0, 5.0]",Psychology,train,5.0,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1007/s13524-014-0321-x,Psychology_131,"""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim.","For first births, parents' happiness trajectories increase sharply before and around the birth and then settle close to pre-birth levels, which is the same result shown earlier in .","In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status. ""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased.","We control for the influence of previous births; without these, the baseline level estimated as four to five years before the birth (separately for each parity) would be influenced by the previous births. For first births, parents' happiness trajectories increase sharply before and around the birth and then settle close to pre-birth levels, which is the same result shown earlier in . Standard errors are estimated using robust methods that account for the clustering of data within individuals.","[1.0, 2.0, 3.0, 1.0]",Psychology,train,1.75,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1016/j.nicl.2015.02.009,Psychology_133,"""What we've shown is that very low doses of the atypical antiepileptic levetiracetam reduces this over-activity,"" Gallagher said.","While overactivity was attenuated by levetiracetam in aMCI cohorts treated with low doses (62.5 and 125 mg BID), decreased EC activation was concurrently normalized, with a significant boost in EC activation at the 62.5 mg BID dose compared to placebo.","They also closely match the results in animal studies performed by the team and scientists elsewhere. ""What we've shown is that very low doses of the atypical antiepileptic levetiracetam reduces this over-activity,"" Gallagher said. ""At the same time, it improves memory performance on a task that depends on the hippocampus.""","In addition to excess fMRI activation, a region of decreased activation in the entorhinal cortex (EC) was observed during task performance, similar to . While overactivity was attenuated by levetiracetam in aMCI cohorts treated with low doses (62.5 and 125 mg BID), decreased EC activation was concurrently normalized, with a significant boost in EC activation at the 62.5 mg BID dose compared to placebo. The observed areas of fMRI activation, consistently localized to the left DG/CA3 subregion in aMCI patients relative to age-matched controls, differed somewhat across cohorts in an anterior to posterior location.","[5.0, 4.0, 3.0, 2.0]",Psychology,train,3.5,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1186/s13229-018-0246-0,Psychology_134,"This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research.""",The participation rate of the communities in this study is much higher than most of the prevalence studies of autism internationally.,"This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research."" In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","It is important for national policy to report data from these first three cities, and our on-going data collection in the seven other cities will serve to further inform national policy and future research directions. The participation rate of the communities in this study is much higher than most of the prevalence studies of autism internationally. Although there will be non-participation effects, these will be much less marked than those experienced by other such studies.","[2.0, 2.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38803735334&p=1pl&v=1&x=Olj8Q_8mSR67vcOaC9l--A
10.1093/chemse/bjt066,Psychology_135,"""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis.","""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","These findings further strengthen the concept that odor perception is influenced by cognitive interpretation. Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis. We found that participants rated geraniol as more intense when it was labeled positively (""fresh flowers"") than when labeled negatively (""cheap perfume"").","[4.0, 2.0, 4.0, 2.0, 3.0]",Psychology,train,3.0,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1093/jcr/ucw012,Psychology_136,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.",This ad was not matched to the browsing behavior or demographic responses in either of the targeted conditions; this allowed us to test the effects of participants' perceptions of being targeted while holding the advertisement constant across conditions.,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","Finally, study 4 shows that implied social labels only affect self-perceptions and behavior when there is a plausible connection between the label and past behavior (i.e., when targeting is at least moderately accurate). This ad was not matched to the browsing behavior or demographic responses in either of the targeted conditions; this allowed us to test the effects of participants' perceptions of being targeted while holding the advertisement constant across conditions. After indicating how much they liked the advertisement (1 ¼ Not at all,","[3.0, 3.0, 2.0, 4.0, 3.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1177/0141076814565942,Psychology_137,The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"Overall, the risk of hyperkinetic disorder was not elevated among ritually circumcised boys in the first 0-4 years of life (HR ¼ 0.99; 95% CI: 0.43-2.29) or in the 5-to 9-year age group (HR ¼ 1.27; 95% CI: 0.95-1.71) ( Table 2) .","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys. Overall, the risk of hyperkinetic disorder was not elevated among ritually circumcised boys in the first 0-4 years of life (HR ¼ 0.99; 95% CI: 0.43-2.29) or in the 5-to 9-year age group (HR ¼ 1.27; 95% CI: 0.95-1.71) ( Table 2) . Among boys in Muslim families, risk of hyperkinetic disorder did not depend on the boys' foreskin status (HR ¼ 1.08; 95% CI: 0.77-1.52).","[3.0, 1.0, 3.0, 3.0, 2.0]",Psychology,train,2.4,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1016/j.jpeds.2017.10.028,Psychology_14,"In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children.","Of these participants, 61% were female, with a mean age of 20.03 (SD = 0.76).","Of the 758 young adults recruited for the study, 61 percent were female. In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship.","One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence. Of these participants, 61% were female, with a mean age of 20.03 (SD = 0.76). Participants were Hispanic (32.6%), white (28.8%), African American (26.0%), and other (12.7%).","[3.0, 4.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1038/s41598-017-03627-7,Psychology_140,"""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein.","Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling.","The more physiologically synchronized they were, the less pain she felt. ""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein. Further research is necessary to figure out precisely how a partner's touch eases pain.","Our findings confirm that interpersonal touch as compared to no-touch is associated with increased respiration coupling, during both pain and no-pain conditions. Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling. The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain.","[5.0, 5.0, 4.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1080/08870446.2013.818674,Psychology_142,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.","Again, the interaction of volitional self-efficacy and smoking-specific received social support was significant (p< .05, see Figure 2 ).","Support from one's partner can help -- but only if the smokers have developed skills of their own that help them to stop. Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations.","Similar results emerged in the second moderator analysis that predicted biochemically verified point prevalence at T2 (see Table 3 , first column). Again, the interaction of volitional self-efficacy and smoking-specific received social support was significant (p< .05, see Figure 2 ). The analysis of the region of significance by the Johnson Neyman technique showed that the simple slopes were significant only at levels of social support higher than 1.86 (p < .05).","[4.0, 5.0, 4.0, 4.0, 2.0]",Psychology,train,3.8,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamapsychiatry.2018.1941,Psychology_143,"This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments.","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep. This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","[3.0, 2.0, 4.0, 5.0, 5.0]",Psychology,train,3.8,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1111/cdev.12370,Psychology_145,"They were also less likely to continue to blame the other person involved in the event, though not less likely to forgive him or her.","Moreover, the inverse relation between self-distancing and emotional reactivity strengthened with age.","These teens were more likely to reconsider the events in meaningful and insightful ways and less likely to simply replay the upsetting events in their minds. They were also less likely to continue to blame the other person involved in the event, though not less likely to forgive him or her. In turn, these new insights were associated with less emotional distress.","As expected, spontaneous self-distancing during reflection predicted lower levels of emotional reactivity by leading adolescents to reconstrue (rather than recount) their experience and blame their partner less. Moreover, the inverse relation between self-distancing and emotional reactivity strengthened with age. These findings highlight the role that self-distancing plays in fostering adaptive self-reflection in adolescence, and begin to elucidate the role that development plays in enhancing the benefits of engaging in this process.","[2.0, 1.0, 3.0, 1.0, 1.0]",Psychology,train,1.6,news,http://www.futurity.org/teens-emotions-distance-903192/
10.1093/jcr/ucw012,Psychology_147,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.",", .0046-.1719), indicating that behavioral targeting increases purchase intentions for the advertised product through the recognition of the implied social label. The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label. Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition).","[5.0, 5.0, 5.0]",Psychology,train,5.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jalz.2018.06.2856,Psychology_148,"Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said.","In contrast, a smaller population-based cohort of 812 in three French cities showed substantially increased dementia risk (odds ratio 3.9, [1.5, 10.4]) in participants with glaucoma during 3 years, but only analyzed 2436 person-years, roughly 1/6 of our follow-up .","""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss,"" Lee explained in a university news release. Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said. ""What we found was not subtle,"" said Paul Crane, a professor of medicine at the university.","Similarly, a retrospective study using 5% of Medicare claims data revealed no increased AD risk in people with glaucoma (n 5 63,235) compared with propensity score-matched people without glaucoma during 14 years of follow-up (HR 0.91, [0.88, 0.93]) . In contrast, a smaller population-based cohort of 812 in three French cities showed substantially increased dementia risk (odds ratio 3.9, [1.5, 10.4]) in participants with glaucoma during 3 years, but only analyzed 2436 person-years, roughly 1/6 of our follow-up . The Rotterdam Study followed 1438 dementia-free participants aged 75 years for an average of 25 months and found increased AD risk in those with advanced AMD (HR 2.1, [1.1, 4.3] ), but this became insignificant with smoking and atherosclerosis included in the model .","[2.0, 4.0, 4.0, 4.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1111/cdep.12038,Psychology_149,"We see consistently that the more children are spanked, the more behavioral problems they have in the years ahead.""",Reducing parents' use of spanking may go a long way toward reducing the number of children who suffer physical abuse each year.,"Moreover, for both boys and girls, she said, ""We found [spanking] linked to more aggression, more delinquent behavior, more mental health problems, worse relationships with parents, and putting the children at higher risk for physical abuse from their parents."" We see consistently that the more children are spanked, the more behavioral problems they have in the years ahead."" UNICEF senior data specialist Claudia Cappa, believes the study provides additional support for the idea that ""violence teaches violence.""","The link between spanking and physical abuse is the most disturbing of these unintended effects, but it should not be a surprising one; both parental acts involve hitting, and purposefully hurting, children. Reducing parents' use of spanking may go a long way toward reducing the number of children who suffer physical abuse each year. Human rights-based arguments have little influence in the United States until we ratify the Convention on the Rights of the Child; the United States is one of only three countries not to have done so (the others are Somalia and South Sudan, the latter of which gained independence in 2011).","[3.0, 2.0, 4.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=37496711489&p=1pl&v=1&x=NWsoYnhIAFQ7txCZZJ6ciQ
10.1001/jamapsychiatry.2018.1941,Psychology_15,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,"Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","We note that the causal relations between sleep and depression is an important topic that deserves much further investigation. Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants. A strength of this investigation is that the effects are likely to be very robust, given the large sample of participants with resting-state fMRI and the cross-validation with the UK Biobank data set with a sample of 8718 participants in one of its first uses of resting-state fMRI data.","[2.0, 5.0, 3.0, 3.0, 3.0]",Psychology,train,3.2,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1093/chemse/bjt066,Psychology_150,"""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","This effect was robust as it was observed for all odors in the present study, and this was in keeping with previous studies .","""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","Odors carrying positive labels were rated as being more pleasant than odors carrying negative labels. This effect was robust as it was observed for all odors in the present study, and this was in keeping with previous studies . As with edibility ratings, ""false alarm"" analysis supported the fact that the effect of pleasantness ratings is due to the presentation of both odors and labels and not solely based on labels.","[2.0, 2.0, 3.0, 3.0]",Psychology,train,2.5,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1111/cdev.12250,Psychology_151,"The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote.","This status-seeking link is important, in that it suggests that at a formative point in social development, some early adolescents are learning to establish connections with their peers by engaging in pseudomature behaviors so as to impress those peers, rather than by learning to connect successfully with them via more adaptive means.","In fact, just the opposite happened. The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","Notably, the adolescents who engaged most in pseudomature behavior were also those who most highly valued being popular (i.e., for whom popularity and status among peers were most important). This status-seeking link is important, in that it suggests that at a formative point in social development, some early adolescents are learning to establish connections with their peers by engaging in pseudomature behaviors so as to impress those peers, rather than by learning to connect successfully with them via more adaptive means. Each of the pseudomature behaviors assessed was linked to teens placing a high value, even relative to their peers, upon being popular.","[2.0, 3.0, 3.0, 3.0, 2.0]",Psychology,train,2.6,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1177/0956797617692041,Psychology_152,The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving.,"On the one hand, bundling could increase purchasing relative to when the same amount is served in one container by creating the illusion of a better value: a two-forone deal.","The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means. The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving. However, it did not affect the further downstream behavior of consumption.","Dividing the same amount of food into multiple containers reduces consumption (by shifting norms and facilitating monitoring; . On the one hand, bundling could increase purchasing relative to when the same amount is served in one container by creating the illusion of a better value: a two-forone deal. However, the study relied on self-reported hypothetical purchase choices, and the result may simply be an artifact of the way orders were elicited (for details, see the Supplemental Material available online).","[4.0, 1.0]",Psychology,train,3.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1016/j.jpeds.2017.10.028,Psychology_153,"According to Temple, this research is just another study to show the negative impacts of corporal punishment.","The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence.","These results remained even when the team accounted for the number of children who experienced child abuse, which is described as any form of punishment that is inappropriate or causes series injury. According to Temple, this research is just another study to show the negative impacts of corporal punishment. For example, although the fear of being hit can temporarily prevent a child from doing a problematic behavior, in the long run it may have psychological consequences.","Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence. Furthermore, variables known to relate to dating violence were controlled for, which highlights the importance of the unique impact of corporal punishment on perpetration of dating violence and addresses longstanding criticisms regarding a potentially confounding link between corporal punishment and poor outcomes.","[3.0, 3.0, 3.0, 2.0, 1.0]",Psychology,train,2.4,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1093/jcr/ucw012,Psychology_154,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","We propose that the effects of behaviorally targeted advertising on self-perceptions and behavior stem from the marketplace metacognition that the marketer has made an individual-level inference about the consumer and not simply from making an identity salient (an alternative account that we rule out empirically), and we directly measure the extent to which consumers believe the marketer has made an inference about them when receiving a behaviorally targeted ad.","""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","Thus a key distinction between our research and past work on identity in advertising ) is consumers' conscious recognition that the marketer has made an inference about them based on their individual-level behavior. We propose that the effects of behaviorally targeted advertising on self-perceptions and behavior stem from the marketplace metacognition that the marketer has made an individual-level inference about the consumer and not simply from making an identity salient (an alternative account that we rule out empirically), and we directly measure the extent to which consumers believe the marketer has made an inference about them when receiving a behaviorally targeted ad. Thus, whereas prior work on identity has shown that making an identity salient can increase the likelihood that consumers engage in identity-consistent behavior , we propose and demonstrate that the effects of behaviorally targeted ads on behavior occur through a different process, one that depends on the recognition that the marketer has made an individual-level inference about the consumer based on his or her past behavior and the adjustments in self-perception that result.","[2.0, 5.0, 2.0, 4.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1186/s13229-018-0246-0,Psychology_155,"In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000.","In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","In Shenzhen, it was 42.3 per 10,000 and 19.0 per 10,000 in Jiamusi. In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000. The strengths of this first large-scale study of autism in China are several.","[4.0, 2.0, 5.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1093/jcr/ucw012,Psychology_156,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","The results further indicate that while consumers recognize even inaccurate behaviorally targeted ads as implied social labels, it is accuracy (i.e., the match between this prior behavior and the implied label) that determines whether this label is perceived to be relevant to the self, leading to adjustments in self-perceptions that play a mediating role in subsequent trait-related behavior.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","Specifically, we found that labels that are unconnected to prior behavior (i.e., inconsistent with consumers' a priori interest in trait-related products) do not prompt adjustments to self-perceptions and affect behavior; low levels of accuracy yield no effect, whereas moderate to high levels of accuracy produce social labeling effects. The results further indicate that while consumers recognize even inaccurate behaviorally targeted ads as implied social labels, it is accuracy (i.e., the match between this prior behavior and the implied label) that determines whether this label is perceived to be relevant to the self, leading to adjustments in self-perceptions that play a mediating role in subsequent trait-related behavior. Importantly, however, we find that adjustments in consumer self-perceptions in response to behaviorally targeted advertisements depend on the plausibility of the connection between the label and past behavior.","[4.0, 4.0, 5.0, 4.0]",Psychology,train,4.25,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-018-30980-y,Psychology_157,"The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","In contrast, with the lack of processing and remodeling directly following learning, information is forgotten across the 24-hour period in the wake condition.","This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues. This delay may reflect ""short-term destabilization of an enriched memory,"" they add.","Greater plasticity over the nap, as indicated by greater SWA, may allow nocturnal SWS to be more effective at consolidating and preserving the memories learned earlier in the day. In contrast, with the lack of processing and remodeling directly following learning, information is forgotten across the 24-hour period in the wake condition. Newly formed memories may be more susceptible to daytime waking interference without plastic changes across the nap.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1111/lcrp.12013,Psychology_158,The researchers found that closing the eyes helped the participants remember both audial and visual information.,"Simple effects analyses showed that, for participants who had closed their eyes at T1, eye-closure at T2 did not significantly affect incorrect recall of visual details (F < 1).","Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer. The researchers found that closing the eyes helped the participants remember both audial and visual information. The researchers found that closing your eyes during an investigation is likely to make you feel less comfortable unless you have built up a good rapport with the questioner.","A three-way ANOVA on the number of incorrect visual details showed no significant effect of condition at T1 (F < 1), but a significant main effect of condition at T2, F(1, 44) = 4.15, p = .048, g 2 = .08, and a significant interaction between condition at T1 and condition at T2, F(1, 44) = 5.18, p = .03, g 2 = .10. Simple effects analyses showed that, for participants who had closed their eyes at T1, eye-closure at T2 did not significantly affect incorrect recall of visual details (F < 1). For participants who had not closed their eyes at T1, however, eye-closure during T2 significantly increased incorrect recall of visual details (see Table 1 ), F(1, 44) = 9.29, p = .004, g 2 = .17.","[2.0, 4.0, 3.0, 2.0, 2.0]",Psychology,train,2.6,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1177/0141076814565942,Psychology_159,They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD.,"ASD risk in girls was not associated with family factors linked to ritual male circumcision (HR ¼ 1.17; 95% CI: 0.54-2.55), based on seven ASD cases in girls with a ritually circumcised brother and 1012 ASD cases in girls without a ritually circumcised brother.","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","For boys in the 0-4 years age interval, risk of infantile autism in circumcised boys was twice that of intact boys (HR ¼ 2.06; 95% CI: 1.36-3.13, based on 27 cases in circumcised boys and 785 cases in intact boys); the risk of all other types of ASD combined was inconspicuous in the same age group (HR ¼ 1.21; 95% CI: 0.55-2.66, based on seven cases in circumcised boys and 540 cases in intact boys). ASD risk in girls was not associated with family factors linked to ritual male circumcision (HR ¼ 1.17; 95% CI: 0.54-2.55), based on seven ASD cases in girls with a ritually circumcised brother and 1012 ASD cases in girls without a ritually circumcised brother. Ritual circumcision among Danish boys is linked to an overall 46-62% increase in ASD risk in the first 10 years of life, with the upper risk estimate obtained after restriction to the period with the most complete data.","[1.0, 4.0, 4.0, 1.0, 2.0]",Psychology,train,2.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1001/jamapsychiatry.2018.1941,Psychology_16,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,"These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","[4.0, 4.0, 3.0, 3.0]",Psychology,train,3.5,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1001/jamapsychiatry.2018.1941,Psychology_160,The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep.,"We note that there is a strong association between depression and poor sleep, in that the correlation found in this study between the Depressive Problems score and PSQI score was high (r = 0.371, P <1.0×10 −10 , Figure 1B) ; however, this does not address the directionality of the association, which could be in both directions.","Results showed that 162 functional connectivity links in the brain were connected with our ability (or lack of) to get some shut-eye; of these, 39 were also linked to depressive problems a such as low self-esteem, low mood, and a lack of motivation. The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""","Most participants were healthy controls, and the depressive score was used as an indicator of depressive symptoms, not formal diagnosis; however, we did demonstrate a high correlation between the Depressive Problems score and whether a person had at some time been diagnosed with depression. We note that there is a strong association between depression and poor sleep, in that the correlation found in this study between the Depressive Problems score and PSQI score was high (r = 0.371, P <1.0×10 −10 , Figure 1B) ; however, this does not address the directionality of the association, which could be in both directions. Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis.","[4.0, 1.0, 3.0, 4.0, 4.0]",Psychology,train,3.2,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1038/s41598-017-03627-7,Psychology_161,"The more physiologically synchronized they were, the less pain she felt.","In addition, a possible explanation for these contradictory findings may rely on the different definitions of synchronization used in the two studies.","""Touch brings it back."" The more physiologically synchronized they were, the less pain she felt. ""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein.","As a result they probably experienced higher levels of pain and distress during the pain condition, which may disrupt the physiological coupling. In addition, a possible explanation for these contradictory findings may rely on the different definitions of synchronization used in the two studies. Here we show that in the absence of touch, the experience of pain disrupted the physiological coupling as the targets probably were focusing on their own pain experience.","[3.0, 2.0, 2.0, 3.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1093/jcr/ucw012,Psychology_162,"While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.","Finally, future research could explore whether an advertisement has to designate explicitly that it has been behaviorally targeted through words or icons (as we have done in our studies) or if there are more subtle cues that lead consumers to believe that an ad has been behaviorally targeted.","""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them. ""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said.","This desire for consistency may have contributed to our results. Finally, future research could explore whether an advertisement has to designate explicitly that it has been behaviorally targeted through words or icons (as we have done in our studies) or if there are more subtle cues that lead consumers to believe that an ad has been behaviorally targeted. In the absence of this explicit labeling (or the understanding of it), there could be psychologically interesting predictors of believing a given ad has been behaviorally targeted, including whether the implied label is positive (vs. negative) or relevant to a central identity for that consumer.","[4.0, 4.0, 3.0, 3.0]",Psychology,train,3.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1007/s13524-014-0321-x,Psychology_163,"""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report.","We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has.","The study demonstrates that not all children cause equally good emotions. ""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report. This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small.","Importantly, we observe that happiness increases before birth, suggesting that the happiness gain around the time of birth may capture not only the effect of the birth but also the complex childbearing process that may involve partnership formation, partnership quality, and increased sexual activity. We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has. These results were similar in Britain and Germany.","[3.0, 4.0, 4.0, 3.0, 3.0]",Psychology,train,3.4,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1093/chemse/bjt066,Psychology_164,"When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label.","In summary, odor labels affect pleasantness ratings and edibility perception.","When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.","All odorants presented with positive labels were rated as being more pleasant than when they were presented with negative labels. In summary, odor labels affect pleasantness ratings and edibility perception. Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label.","[2.0, 4.0, 5.0, 4.0]",Psychology,train,3.75,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1038/s41598-018-30980-y,Psychology_165,"""This study demonstrates that napping is beneficial to memory processing,"" they point out.","For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 .","As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","If such were the case, REM in subsequent overnight sleep may support delayed emotional memory processing. For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 . Likewise, negative memories selectively cued during SWS are better remembered than uncued items 8 .","[2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jamapsychiatry.2018.1941,Psychology_166,Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample.,IMPORTANCE Depression is associated with poor sleep quality.,"Among those with depression, researchers found a strong connection between the dorsolateral prefrontal cortex, which is associated with short-term memory; the precuneus, which is associated with the self, and the lateral orbitofrontal cortex, which is associated with negative emotion. Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[2.0, 5.0, 1.0, 3.0, 1.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1093/jcr/ucw012,Psychology_167,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","On one hand, consumers are more interested in information about where they stand on traits and identities that are important to them, which may make the effects of behaviorally targeted ads stronger for important traits .","""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","Additionally, it would be useful to investigate the role of the importance (to the self) of the trait implied from the label ). On one hand, consumers are more interested in information about where they stand on traits and identities that are important to them, which may make the effects of behaviorally targeted ads stronger for important traits . On the other hand, consumers' selfperceptions on traits that are very important to them are arguably less malleable , which may mute these effects.","[4.0, 3.0, 2.0, 4.0, 4.0]",Psychology,train,3.4,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-018-30980-y,Psychology_168,"""This study demonstrates that napping is beneficial to memory processing,"" they point out.","predict ΔRecall 24-hr (B = −0.005, p = 0.983), nor was there a significant relationship between ΔRecall 24hr and the average SWA across both the nap and the overnight sleep bouts (B = −0.081, p = 0.936).","As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","When children napped, it took them longer to Table 2 . predict ΔRecall 24-hr (B = −0.005, p = 0.983), nor was there a significant relationship between ΔRecall 24hr and the average SWA across both the nap and the overnight sleep bouts (B = −0.081, p = 0.936). In light of the reduced accuracy across the nap predicting improvements in accuracy overnight (Fig.","[1.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1073/pnas.1505114112,Psychology_169,The findings suggest that music instruction helps enhance skills that are critical for academic success.,"Thus, music training initiated as late as adolescence can enhance neural processing of sound and confer benefits for language skills.","The findings suggest that music instruction helps enhance skills that are critical for academic success. The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment. ""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" says Nina Kraus, senior study author and director of the Auditory Neuroscience Laboratory at Northwestern University.","Although phonological processing improved in both the music training and active control groups, the enhancement was greater in adolescents who underwent music training. Thus, music training initiated as late as adolescence can enhance neural processing of sound and confer benefits for language skills. These results establish the potential for experience-driven brain plasticity during adolescence and demonstrate that in-school programs can engender these changes.","[2.0, 4.0, 5.0, 4.0]",Psychology,train,3.75,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1177/0141076814565942,Psychology_17,The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96).,"They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.",Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13). Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96). Associations with asthma were consistently inconspicuous (HR ¼ 0.96; 95% CI: 0.84-1.10).,"[5.0, 5.0, 2.0, 3.0]",Psychology,train,5.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1038/s41598-017-03627-7,Psychology_170,"""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said.","Thus, it could be suggested that inter-personal physiological coupling underlie touch-related analgesia.","When he was allowed to hold her hand, their rates fell into sync again and her pain decreased. ""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said. ""Touch brings it back.""","This indicates that coupling . Thus, it could be suggested that inter-personal physiological coupling underlie touch-related analgesia. In contrast to our original hypothesis, pain did not increase physiological coupling in the absence of the partner's touch.","[2.0, 5.0, 5.0, 3.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1007/s13524-014-0321-x,Psychology_171,"A first-born child brought the most happiness, no matter what age the parents were.","If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced.","Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness. A first-born child brought the most happiness, no matter what age the parents were. There was a 50 percent decrease in happiness during the birth of a second child, followed by a total slump by the time the third child is born.","is an exception: they found that first births have a positive effect on parental happiness, but higher order births do not. If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced. Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution.","[4.0, 5.0, 1.0, 5.0, 4.0]",Psychology,train,5.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1080/08870446.2013.818674,Psychology_172,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.",The rationale for examining potential joint effects of smoking-specific received social support and individual self-regulation before the quit date and post-quit date smoking cessation in the short-term rather than a longer-term ( 6 months) perspective lies in the chosen constructs.,"Support from one's partner can help -- but only if the smokers have developed skills of their own that help them to stop. Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations.","On average, 29 days (range 21-58days) after the quit date, the respondents returned to the lab for the second assessment (T2). The rationale for examining potential joint effects of smoking-specific received social support and individual self-regulation before the quit date and post-quit date smoking cessation in the short-term rather than a longer-term ( 6 months) perspective lies in the chosen constructs. In contrast to perceived social support, received social support is not assumed to be stable over time, but a measure of retrospective support transactions from the partner.","[5.0, 1.0, 2.0, 4.0, 4.0]",Psychology,train,4.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamapsychiatry.2013.4081,Psychology_173,"While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29.","Compared with the offspring of mothers aged 25 to 29 years, the offspring of mothers aged 12 to 19 years had a 51% increased risk of having a mental disorder (IRR, 1.51 [95% CI, 1.48-1.54]).","Results for older parents were varied as well. While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29. The study adds to a growing body of research focused on the specific effects of parental age.","Considering the broadest category of any psychiatric diagnosis (ICD-10-DCR codes F00-F99) as the outcome of interest, the offspring of the youngest mothers were at the highest risk for any mental disorders. Compared with the offspring of mothers aged 25 to 29 years, the offspring of mothers aged 12 to 19 years had a 51% increased risk of having a mental disorder (IRR, 1.51 [95% CI, 1.48-1.54]). No significantly increased risk for the offspring of older mothers was found.","[1.0, 2.0, 2.0, 1.0]",Psychology,train,1.5,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1176/appi.ajp.2018.17111282,Psychology_175,"The team analyzed four tests (CNSDose, Genecept, GeneSight, and Neuropharmagen) and found that they could reliably detect whether someone has a certain genetic variant, says Dunlop.",Identifying genetic variants with the greatest empirical support is critical for evaluating and implementing combinatorial pharmacogenetic testing.,"""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments. The team analyzed four tests (CNSDose, Genecept, GeneSight, and Neuropharmagen) and found that they could reliably detect whether someone has a certain genetic variant, says Dunlop. The tests they researched also didn't agree on what medical recommendations to make when they detected that a patient had a particular gene variant.","Conversely, knowledge that a patient's genotype predicted poor metabolism by the enzymes regulating pharmacokinetics of a candidate medication might portend tolerability problems even at low dosages and perhaps prompt a prescriber to use a very low dosage or to avoid that agent altogether. Identifying genetic variants with the greatest empirical support is critical for evaluating and implementing combinatorial pharmacogenetic testing. The PharmGKB level-of-evidence scale for gene-drug interactions ranges from preliminary evidence of association (level 4) to significant associations with strong effect sizes that have been replicated in multiple cohorts (level 1A).","[3.0, 2.0, 2.0, 1.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1111/cdev.12250,Psychology_176,"At 13, those who exhibited ""pseudomature behaviors"" -- a catchall term for behaviors that seem to boost perceived popularity -- were rated as more popular by their peers.",Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future.,"""It appears that while so-called cool teens' behavior might have been linked to early popularity, over time, these teens needed more and more extreme behaviors to try to appear cool,"" Joseph P. Allen, lead author and professor of psychology at the University of Virginia, said in statement. At 13, those who exhibited ""pseudomature behaviors"" -- a catchall term for behaviors that seem to boost perceived popularity -- were rated as more popular by their peers. The cooler kids impressed their peers through displays of romantic behavior (like kissing or touching), deviant acts (like damaging their parents' property or sneaking into a movie theater without a ticket), or by associating themselves with more physically attractive friends.","Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use. Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future. For example, if pseudomature behavior leaves early adolescents more likely to associate with deviant teens and more likely to believe that relying upon deviant behaviors is a useful way of impressing peers, then such behavior would likely place teens at greater risk of engaging in more serious deviant behavior going forward.","[5.0, 4.0, 2.0, 2.0, 1.0]",Psychology,train,2.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1080/08870446.2013.818674,Psychology_177,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.",Future research should explore these findings further and develop interventions to provide smokers who intend to quit with the best possible conditions.,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations. Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette).","As people who live with a smoking partner have an increased risk for several diseases compared to those living with a non-smoker , providing social support to help the partner to quit smoking is also beneficial for themselves. Concluding, the study yielded the first evidence for the importance of the combination of individual and social factors in smoking cessation. Future research should explore these findings further and develop interventions to provide smokers who intend to quit with the best possible conditions.","[3.0, 3.0, 3.0, 3.0, 2.0]",Psychology,train,2.8,news,http://www.healthcanal.com/substance-abuse/41119-rauchstopp-zu-zweit.html
10.1111/cdep.12038,Psychology_178,"Although spanking is traditionally supposed to teach a lesson to correct bad behavior, children who were spanked were neither more compliant nor better behaved.","The link between spanking and physical abuse is the most disturbing of these unintended effects, but it should not be a surprising one; both parental acts involve hitting, and purposefully hurting, children.","""The findings were consistently negative,"" she said. Although spanking is traditionally supposed to teach a lesson to correct bad behavior, children who were spanked were neither more compliant nor better behaved. Moreover, for both boys and girls, she said, ""We found [spanking] linked to more aggression, more delinquent behavior, more mental health problems, worse relationships with parents, and putting the children at higher risk for physical abuse from their parents.""","Children who are spanked are more likely to attribute hostile intentions to others, attributions that in turn increase the likelihood that they will behave aggressively in social interactions . The link between spanking and physical abuse is the most disturbing of these unintended effects, but it should not be a surprising one; both parental acts involve hitting, and purposefully hurting, children. Reducing parents' use of spanking may go a long way toward reducing the number of children who suffer physical abuse each year.","[3.0, 2.0, 2.0, 2.0]",Psychology,train,2.25,news,http://ct.moreover.com/?a=37496711489&p=1pl&v=1&x=NWsoYnhIAFQ7txCZZJ6ciQ
10.1111/cdev.12250,Psychology_179,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time. Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use. Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future.","[5.0, 4.0, 5.0, 4.0, 5.0]",Psychology,train,4.6,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1177/0141076814565942,Psychology_18,"""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""","Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority.","Risk was particularly high for infantile autism before the age of five, at least in epidemiology. The researchers say that the pain associated with circumcision in very young babies is likely to be more severe during the operation and post-operatively. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""","This finding, and the unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families, need attention, particularly because data limitations most likely rendered our HR estimates conservative. Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority. Among children operated for a variety of conditions, Levy noted a strong association between the age at operation and the frequency and severity of emotional sequelae.","[3.0, 5.0, 3.0, 3.0]",Psychology,train,3.5,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1093/jcr/ucw012,Psychology_180,"While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.",Study 2 also provides evidence that behaviorally targeted ads have unique effects relative to an identity salience prime and demonstrates that the effects of behaviorally targeted ads on purchase intentions persist over time.,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals. Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner.",Study 2 demonstrates that the effects of behavioral targeting on purchase intentions are mediated by the recognition that the ad implies something about the consumer's identity and the subsequent adjustments in self-perceptions that result from recognizing this implied label. Study 2 also provides evidence that behaviorally targeted ads have unique effects relative to an identity salience prime and demonstrates that the effects of behaviorally targeted ads on purchase intentions persist over time. Study 3 shows that the serial mediation tested in study 2 holds not just for purchase intentions for the advertised product but also for other behaviors conceptually related to the label.,"[3.0, 2.0, 3.0, 4.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1073/pnas.1509654112,Psychology_181,"But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains.","Our findings are robust across sample, age, type of MRI, and method of analysis.","They found 29 regions that seem to be different sizes in people who identified as male or female. But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains. While itaEUR(tm)s possible to have predominantly female components or predominantly male components to your brain, researchers found that most people are in the middle.","Moreover, analyses of internal consistency reveal that brains with features that are consistently at one end of the ""maleness-femaleness"" continuum are rare. Our findings are robust across sample, age, type of MRI, and method of analysis. These findings are corroborated by a similar analysis of personality traits, attitudes, interests, and behaviors of more than 5,500 individuals, which reveals that internal consistency is extremely rare.","[2.0, 1.0, 1.0, 1.0]",Psychology,train,1.25,news,http://healthmedicinet.com/news/science-proves-men-and-women-are-actually-from-the-same-planet/
10.1093/jcr/ucw012,Psychology_182,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","We do note, however, that motivated reasoning ) may also play a role in determining what label consumers believe the ad implies because consumers may be motivated to accept a more socially desirable or positive label.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","We expect that the consumer will only accept, and subsequently exhibit behavior consistent with, the label that he or she perceives to be most connected to past behavior. We do note, however, that motivated reasoning ) may also play a role in determining what label consumers believe the ad implies because consumers may be motivated to accept a more socially desirable or positive label. Additionally, it would be useful to investigate the role of the importance (to the self) of the trait implied from the label ).","[3.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,3.2,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-018-30980-y,Psychology_183,"This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children.""",4) .,"A significant benefit of napping was observed only when changes across the entire 24-hour period were considered. This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","These results support that the relationship between memory performance change across both the nap and overnight sleep bouts was fully mediated by nap SWA (Fig. 4) . Individually, the nap and overnight sleep bouts were not sufficient to induce changes in memory.","[3.0, 1.0, 1.0, 1.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1073/pnas.1505114112,Psychology_184,"[related]

All participants improved in language skills important for language and reading, but the improvement was greater for those in music classes, compared with the ROTC group.","These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls.","They also demonstrated prolonged heightened brain sensitivity to sound details. [related]

All participants improved in language skills important for language and reading, but the improvement was greater for those in music classes, compared with the ROTC group. ""Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during the teenage years,"" the authors write.","The music training group also exhibited earlier emergence of the adult cortical response, suggesting that in-school music accelerates neurodevelopment. These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls. Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years.","[4.0, 4.0, 5.0, 4.0, 3.0]",Psychology,train,4.0,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1093/jcr/ucw012,Psychology_185,"If an ad makes you feel sophisticated or environmentally conscious, you are more likely to engage in all kinds of behaviors related to that trait - not just buy the advertised product,"" Reczek said.","The results show that behaviorally targeted ads result in increased purchase intentions for the advertised product, an effect mediated by consumers' recognition of the ad as an implied social label.","""The reason this works is because it is changing your self-perceptions first. If an ad makes you feel sophisticated or environmentally conscious, you are more likely to engage in all kinds of behaviors related to that trait - not just buy the advertised product,"" Reczek said. For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad.","The effects proposed in hypotheses 1 and 2 only hold when the implied label is plausibly connected to consumers' prior behavior (i.e., when behavioral targeting is at least moderately accurate). The results show that behaviorally targeted ads result in increased purchase intentions for the advertised product, an effect mediated by consumers' recognition of the ad as an implied social label. Study 2 demonstrates that the effects of behavioral targeting on purchase intentions are mediated by the recognition that the ad implies something about the consumer's identity and the subsequent adjustments in self-perceptions that result from recognizing this implied label.","[4.0, 3.0, 3.0, 3.0]",Psychology,train,3.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1007/s13524-014-0321-x,Psychology_187,"""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim.","If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced.","In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status. ""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased.","is an exception: they found that first births have a positive effect on parental happiness, but higher order births do not. If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced. Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution.","[2.0, 3.0, 2.0]",Psychology,train,2.333333333333333,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1001/jamapsychiatry.2013.4081,Psychology_188,But it's not the first to find that an older father might make you more prone to psychiatric illness.,"In other words, an increased risk for a set of mental disorders in the offspring appears to be associated with younger mothers and older fathers.","The study adds to a growing body of research focused on the specific effects of parental age. But it's not the first to find that an older father might make you more prone to psychiatric illness. This should serve as a caution to men--just because they don't have the same time limits to reproduction that women do doesn't mean there isn't a prime window in their fertility, too.","For example, with respect to maternal age, several disorders have an increased risk in the offspring of younger (teenaged) mothers but no marked increased in the offspring of older mothers, plus an increased risk in the offspring of older (≥45 years) fathers but little or no marked increase in the offspring of younger fathers. In other words, an increased risk for a set of mental disorders in the offspring appears to be associated with younger mothers and older fathers. Our study draws particular attention to the links between younger mothers and a range of mental disorders.","[4.0, 3.0, 3.0]",Psychology,train,3.333333333333333,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1093/jcr/ucw012,Psychology_189,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","The results of study 2 therefore support our proposition that the effect of receiving a behaviorally targeted ad is distinct from that of successful identity salience manipulations, but they do not necessarily imply that targeted ads are more impactful under all circumstances.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","These results therefore show that the identity prime used in the main study was successful in at least temporarily increasing interest in sophisticated activities, even though we did not observe an effect of the prime on purchase intentions in the main study. The results of study 2 therefore support our proposition that the effect of receiving a behaviorally targeted ad is distinct from that of successful identity salience manipulations, but they do not necessarily imply that targeted ads are more impactful under all circumstances. We speculate on the conditions that strengthen and weaken each of these processes in the general discussion section.","[1.0, 4.0, 3.0, 3.0]",Psychology,train,2.75,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1177/0141076814565942,Psychology_19,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.","Results: With a total of 4986 ASD cases, our study showed that regardless of cultural background circumcised boys were more likely than intact boys to develop ASD before age 10 years (HR ¼ 1.46; 95% CI: 1.11-1.93).","The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","Results: With a total of 4986 ASD cases, our study showed that regardless of cultural background circumcised boys were more likely than intact boys to develop ASD before age 10 years (HR ¼ 1.46; 95% CI: 1.11-1.93). Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13). Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96).","[4.0, 5.0, 4.0]",Psychology,train,4.333333333333333,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1007/s13524-014-0321-x,Psychology_190,"Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child.","Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility.","Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses."" Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child. Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain.","Decreasing gains in subjective well-being at higher birth orders may inhibit people from moving to parity three. Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility. In addition to the type of social learning about the optimal timing and number of children to have , fertility decisions may be affected by observing the subjective experiences of others.","[1.0, 2.0, 1.0]",Psychology,train,1.3333333333333333,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1080/14635240.2015.1029641,Psychology_191,"Simply put, we think better on our feet than in our seat.""",The findings indicate that students provided with stand-biased desks did not decrease in their academic engagement in the classroom when compared with their seated counterparts.,"Benden says he wasn't surprised at the results of the study, given that previous research has shown that physical activity, even at low levels, may have beneficial effects on cognitive ability. Simply put, we think better on our feet than in our seat."" The key lesson to take from this research, Benden says, is that school districts that put standing desks in classrooms may be able to address two problems at the same time: academic performance and childhood obesity.","Second graders' engagement score of 1.20 was lower than third graders ( p ¼ 0.39), and the fourth graders have a higher score of 2.28 than third graders ( p ¼ 0.19). The findings indicate that students provided with stand-biased desks did not decrease in their academic engagement in the classroom when compared with their seated counterparts. The significance of this finding is twofold.","[2.0, 5.0, 3.0, 2.0]",Psychology,train,4.0,news,http://www.futurity.org/standing-desks-child-attention-905882/
10.1111/cdep.12038,Psychology_192,"The report found that, globally, about 300 million children between the ages of 2 and 4 experienced physical punishment or verbal abuse from their parents of caregivers, and in some countries, children as young as 12 months old were subject to hitting.",It is time to stop hitting our children in the name of discipline.,"""A child exposed to violence at home is very likely to use violence against peers in school"" and in later life as well, she says. The report found that, globally, about 300 million children between the ages of 2 and 4 experienced physical punishment or verbal abuse from their parents of caregivers, and in some countries, children as young as 12 months old were subject to hitting. Legislated bans send a clear message that this kind of discipline is not acceptable, says Cappa.","By using the euphemistic term spanking, parents feel justified in hitting their children while not acknowledging that they are, in fact, hitting. We as a society have agreed that hitting is not an effective or acceptable way for adults to resolve their differences, so it should not be a surprise that hitting children, like hitting adults, causes more problems than it solves. It is time to stop hitting our children in the name of discipline.","[2.0, 4.0, 2.0, 5.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=37496711489&p=1pl&v=1&x=NWsoYnhIAFQ7txCZZJ6ciQ
10.1001/jamapsychiatry.2018.1941,Psychology_193,"The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep.","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep. This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","[2.0, 4.0, 4.0, 4.0]",Psychology,train,3.5,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1111/cdev.12250,Psychology_195,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.",behaviors predict far greater future risk than has heretofore been recognized.,"For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","***p < .001. behaviors predict far greater future risk than has heretofore been recognized. In terms of competence with peers, pseudomature behavior in early adolescence predicted not only declining popularity with peers across adolescence but also lower levels of peer competence, as rated by peers, in early adulthood.","[3.0, 4.0, 3.0, 1.0, 2.0]",Psychology,train,2.6,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1093/jcr/ucw012,Psychology_196,One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.,We identify how behavioral targeting is distinct from traditional forms of targeting and empirically demonstrate the conditions under which these characteristics prompt unique psychological consequences for consumers.,"For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","First, we provide an early inquiry into the effects of behaviorally targeted ads. We identify how behavioral targeting is distinct from traditional forms of targeting and empirically demonstrate the conditions under which these characteristics prompt unique psychological consequences for consumers. Specifically, by showing that consumers viewing a behaviorally targeted ad recognize an implied label from a marketer, we integrate the literatures on marketplace metacognition and consumer response to firms' digital marketing efforts (e.g., .","[1.0, 2.0, 2.0, 3.0, 3.0]",Psychology,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1001/jamapsychiatry.2018.1941,Psychology_197,A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans.,"3B shows that there is a high positive correlation (r=0.524, p< 1.0×10 -30 ) between the r values for the correlation between the functional connectivity links for the whole brain and the sleep duration based on the HCP and Biobank datasets.","Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","The association patterns between FCs and sleep duration are very similar in both the HCP dataset and the Biobank dataset (Fig. 3B shows that there is a high positive correlation (r=0.524, p< 1.0×10 -30 ) between the r values for the correlation between the functional connectivity links for the whole brain and the sleep duration based on the HCP and Biobank datasets. Further, a Fisher's test also confirmed the correlation (p<10 -10 ).","[1.0, 2.0, 3.0, 3.0, 5.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1073/pnas.1322295111,Psychology_198,Results from this task demonstrated that subjects with injuries to their insula tended to not be biased by the frequency that either color ended up being chosen.,"Here, insula patients distributed their choices between the two color options, and showed no apparent differences in basic 'stickiness' or self-reported confidence, but they deviated from the other groups in that they did not show a gambler's fallacy bias.","Instead, subjects suffering from these injuries cut their losses and chose to stop playing when they hit a near-miss. Results from this task demonstrated that subjects with injuries to their insula tended to not be biased by the frequency that either color ended up being chosen. Instead, they were likely to stick to the same color trial after trial.","These data provide the first evidence for the causal involvement of the insula region in some of the cognitions characteristic of gambling behavior. Here, insula patients distributed their choices between the two color options, and showed no apparent differences in basic 'stickiness' or self-reported confidence, but they deviated from the other groups in that they did not show a gambler's fallacy bias. An intriguing feature is that the averaged data for the insula group displayed modest positive recency in their roulette color choice (Fig.","[3.0, 4.0, 4.0, 4.0, 3.0]",Psychology,train,3.6,news,http://arstechnica.com/science/2014/04/brain-damage-can-make-people-immune-to-the-gamblers-fallacy/
10.1038/s41598-018-30980-y,Psychology_199,"This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children.""","As such, emotional memories may benefit from SWS presence in the naps, which accounts for 42% of naps at this age.","A significant benefit of napping was observed only when changes across the entire 24-hour period were considered. This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","Likewise, negative memories selectively cued during SWS are better remembered than uncued items 8 . As such, emotional memories may benefit from SWS presence in the naps, which accounts for 42% of naps at this age. Naps in early childhood support declarative memory consolidation.","[1.0, 3.0, 4.0, 3.0]",Psychology,train,2.75,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jamapsychiatry.2018.1941,Psychology_20,A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans.,"A total of 162 functional connectivity links involving areas associated with sleep, such as the precuneus, anterior cingulate cortex, and the lateral orbitofrontal cortex, were identified.","Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001). A total of 162 functional connectivity links involving areas associated with sleep, such as the precuneus, anterior cingulate cortex, and the lateral orbitofrontal cortex, were identified. Of these links, 39 were also associated with the Depressive Problems scores.","[4.0, 5.0, 4.0]",Psychology,train,4.333333333333333,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1111/cdep.12038,Psychology_200,"The parents in Holden's study were spanking their children, however, at a median frequency rate of 18 times a week -- or 936 times a year.","Finally, in a study of 440 families that followed children over the transition to adolescence, both the spanking and child effect paths were significant .","Other proven approaches

Although the sample size of this study was small, its findings suggest that many parents weren't telling the truth in previous surveys about corporal punishment practices in their homes. The parents in Holden's study were spanking their children, however, at a median frequency rate of 18 times a week -- or 936 times a year. Needless to say, that's an appalling -- and depressing -- statistic.","Moving to the elementary school years, a study of a nationally representative sample of 11,044 children found both the spanking effect and child effect to be significant over the period from kindergarten to third grade . Finally, in a study of 440 families that followed children over the transition to adolescence, both the spanking and child effect paths were significant . In these studies, although children's aggressive behavior often elicited more spanking over time, this effect did not entirely explain the association between spanking and children's aggression.","[5.0, 2.0, 2.0]",Psychology,train,2.0,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1186/s13229-018-0246-0,Psychology_201,"""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","Most of the children identified in this study using these contemporary screening and diagnostic measures had not previously received an autism diagnosis, confirming underdiagnosis of autism in mainstream schools.","In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China. We have been able to use a standardized screening methodology, allowing us to compare the results with Western countries to show that autism occurs broadly at the same rate, irrespective of culture.""","This high estimate may have resulted from the particular screening and assessment instruments used . Most of the children identified in this study using these contemporary screening and diagnostic measures had not previously received an autism diagnosis, confirming underdiagnosis of autism in mainstream schools. Second, we report autism prevalence in mainstream schools only in Shenzhen and Jiamusi cities.","[1.0, 2.0, 4.0, 2.0, 1.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1016/j.jalz.2018.06.2856,Psychology_202,"Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said.","When we separated recent vs. established ophthalmic conditions, we found a 46% higher AD risk in participants with recent glaucoma compared with those without, but no increased risk for those with established glaucoma.","""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss,"" Lee explained in a university news release. Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said. ""What we found was not subtle,"" said Paul Crane, a professor of medicine at the university.","Without a temporal window, 20% higher AD risk was found in participants with AMD and 44% higher AD risk in those with DR compared with those without. When we separated recent vs. established ophthalmic conditions, we found a 46% higher AD risk in participants with recent glaucoma compared with those without, but no increased risk for those with established glaucoma. In comparison with those without AMD, AD risk in participants with recent and established AMD were 20% and 50% higher; only the latter was statistically different from the null.","[4.0, 4.0, 3.0, 3.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1016/j.jalz.2018.06.2856,Psychology_203,"Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions.","Even though our primary outcome was clinical AD diagnosis, we found similar relationships with all-cause dementia with all three ophthalmic conditions (Supplementary Table 1 ).","""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions. Cataract diagnosis was not an Alzheimer's disease risk factor.","It is common to evaluate risk factors in the larger group of people with clinical diagnoses and attempt to confirm those risk factors with more specific neuropathology data in the smaller subset of individuals who have died and come to autopsy. Even though our primary outcome was clinical AD diagnosis, we found similar relationships with all-cause dementia with all three ophthalmic conditions (Supplementary Table 1 ). The 5-year cutoff to delineate recent versus established condition could be viewed as a limitation.","[3.0, 4.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1007/s13524-014-0321-x,Psychology_204,The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby.,"However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births.","This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small. The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby. In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status.","Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution. However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births. These differences may be moderated by the welfare state.","[1.0, 3.0, 2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1093/jcr/ucw012,Psychology_207,"While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.","The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label.","""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them. ""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said.",", .0046-.1719), indicating that behavioral targeting increases purchase intentions for the advertised product through the recognition of the implied social label. The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label. Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition).","[4.0, 2.0, 3.0, 2.0]",Psychology,train,2.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/s41598-018-30980-y,Psychology_208,"Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report.",4) .,"To do this, they presented children ages approximately three to five years (34-64 months) with faces paired with mean or nice word descriptions, but they saw no significant main effects of emotional valence on recognition memory. Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","These results support that the relationship between memory performance change across both the nap and overnight sleep bouts was fully mediated by nap SWA (Fig. 4) . Individually, the nap and overnight sleep bouts were not sufficient to induce changes in memory.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_209,The happiness level of parents varied among different ages.,"Our modeling approach, which follows with some modifications, 5 allows observing anticipation, shortterm (1 to 4 years) changes, and long-term (5 to 18 years) changes in happiness over the transition to parenthood while controlling for time-invariant unobserved characteristics, such as personality or genetic endowments.","On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.","We assume the cardinality of life satisfaction because treating life satisfaction as ordinal versus cardinal makes little difference . Our modeling approach, which follows with some modifications, 5 allows observing anticipation, shortterm (1 to 4 years) changes, and long-term (5 to 18 years) changes in happiness over the transition to parenthood while controlling for time-invariant unobserved characteristics, such as personality or genetic endowments. 3) , education (Fig.","[4.0, 3.0, 1.0, 4.0]",Psychology,train,3.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1016/j.jpeds.2017.10.028,Psychology_21,"In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498).","Of the 758 young adults recruited for the study, 61 percent were female. In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","[3.0, 4.0, 5.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1176/appi.ajp.2018.17111282,Psychology_210,"""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments.","The study was not specific to patients with a primary diagnosis of major depressive disorder, who represented 42.6% of subjects; primary diagnoses of bipolar disorder and anxiety disorder represented 17.2% and 28.9% of subjects, respectively.","The doctor still isn't supposed to suggest changing medication until they have you genetically tested again by an independent lab. ""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments. The team analyzed four tests (CNSDose, Genecept, GeneSight, and Neuropharmagen) and found that they could reliably detect whether someone has a certain genetic variant, says Dunlop.","Although ""positive results"" were announced, it appears that the primary outcome measure, a statistically significant reduction in HAM-D score from baseline to week 8 among subjects receiving GeneSight testing in comparison with treatment as usual, was not achieved. The study was not specific to patients with a primary diagnosis of major depressive disorder, who represented 42.6% of subjects; primary diagnoses of bipolar disorder and anxiety disorder represented 17.2% and 28.9% of subjects, respectively. Data from clinician surveys for 625 patients were obtained.","[1.0, 2.0, 2.0, 1.0, 1.0]",Psychology,train,1.4,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1093/jcr/ucw012,Psychology_211,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""",We propose that the influence of this implied label on consumers' self-perceptions depends on the extent to which the consumer believes the label accurately reflects his or her past behavior.,"""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","First, people must engage in behavior that can be used as the basis for self-perception ). We propose that the influence of this implied label on consumers' self-perceptions depends on the extent to which the consumer believes the label accurately reflects his or her past behavior. In such a situation, consumers would not perceive the label to be generated as a result of their own behavior and, as a result, that label would not be accepted and would therefore not impact their self-perceptions and future actions ; ).","[3.0, 4.0, 2.0, 4.0, 3.0]",Psychology,train,3.2,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-018-30980-y,Psychology_213,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.",Experimenter ratings of mood also did not differ across conditions.,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","Children's self-report of both sleepiness and mood in session 1 (following immediate recognition) did not differ across conditions (p's > 0.20). Experimenter ratings of mood also did not differ across conditions. However, experimenters did rate children as significantly more sleepy in the nap condition after both Memory Performance.","[1.0, 1.0, 1.0, 1.0, 2.0]",Psychology,train,1.2,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1111/lcrp.12013,Psychology_214,The researchers found that closing the eyes helped the participants remember both audial and visual information.,"The findings extend previous research in showing that the eye-closure instruction can still be effective when witnesses are interviewed repeatedly, and that it can facilitate the elicitation of new information.","Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer. The researchers found that closing the eyes helped the participants remember both audial and visual information. The researchers found that closing your eyes during an investigation is likely to make you feel less comfortable unless you have built up a good rapport with the questioner.","Conclusions. The findings extend previous research in showing that the eye-closure instruction can still be effective when witnesses are interviewed repeatedly, and that it can facilitate the elicitation of new information. Thus, the eye-closure instruction constitutes a simple and time-efficient interview tool for police interviewers.","[5.0, 4.0, 4.0]",Psychology,train,4.333333333333333,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1093/jcr/ucw012,Psychology_215,"When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer.","In order for consumers to adjust their self-perceptions and behaviors in response to the receipt of a behaviorally targeted ad, they must accept the social label implied by the ad.","""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said. When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer. Those are the types of labels that can change people's views about themselves.","H1: Behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to self-perceptions and behavior consistent with the label. In order for consumers to adjust their self-perceptions and behaviors in response to the receipt of a behaviorally targeted ad, they must accept the social label implied by the ad. We propose that acceptance of the label will depend on the accuracy of the targeting-that is, the extent to which the label is plausibly connected to consumers' past behavior.","[3.0, 2.0, 3.0, 4.0]",Psychology,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1111/cdep.12038,Psychology_216,"Although spanking is traditionally supposed to teach a lesson to correct bad behavior, children who were spanked were neither more compliant nor better behaved.","But there is a third reason not to spank our children, and that is a moral one.","""The findings were consistently negative,"" she said. Although spanking is traditionally supposed to teach a lesson to correct bad behavior, children who were spanked were neither more compliant nor better behaved. Moreover, for both boys and girls, she said, ""We found [spanking] linked to more aggression, more delinquent behavior, more mental health problems, worse relationships with parents, and putting the children at higher risk for physical abuse from their parents.""","We thus have research-based and humanrights-based reasons for not spanking our children. But there is a third reason not to spank our children, and that is a moral one. By using the euphemistic term spanking, parents feel justified in hitting their children while not acknowledging that they are, in fact, hitting.","[1.0, 5.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=37496711489&p=1pl&v=1&x=NWsoYnhIAFQ7txCZZJ6ciQ
10.1001/jamapsychiatry.2018.1941,Psychology_217,"""This study may also have implications for a deeper understanding of depression,"" he said.",This provides evidence that some areas can be associated with depressive symptoms even in individuals who had never been diagnosed with depression.,"Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","If the 92 participants who had ever been diagnosed with depression were removed from this analysis, the correlations of some of these areas with the Depressive Problems score were still significant, including the anterior cingulate gyrus and middle frontal gyrus (middle frontal gyrus with right anterior cingulate cortex: r = 0.115; P = .001; left cuneus with left superior frontal gyrus, dorsolateral: r = −0.109; P = .002; right inferior parietal gyrus, excluding supramarginal and angular gyri with left middle cingulate and paracingulate gyri: r = 0.059; P = .01; right middle frontal gyrus with left anterior cingulate cortex: r = 0.059; P = .01; left postcentral gyrus with left inferior temporal lobe: r = 0.059; P = .01; eTable 2 in the Supplement). This provides evidence that some areas can be associated with depressive symptoms even in individuals who had never been diagnosed with depression. However, all of the links involving the lateral orbitofrontal cortex became nonsignificant if this subgroup of 92 individuals was removed (eTable 3 in the Supplement).","[3.0, 3.0, 1.0, 2.0, 3.0]",Psychology,train,2.4,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1080/08870446.2013.818674,Psychology_219,Support from one's partner can help -- but only if the smokers have developed skills of their own that help them to stop.,"As the minimum and maximum of the mean-centred smokingspecific received social support were -2.20 and 1.94, simple slopes for individuals reporting high and low levels of smoking-specific social support were significant (at the 10% level).","Support from one's partner can help -- but only if the smokers have developed skills of their own that help them to stop. Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations.","than 1.87, the association between volitional self-efficacy and continuous abstinence was significant (p<.lO). As the minimum and maximum of the mean-centred smokingspecific received social support were -2.20 and 1.94, simple slopes for individuals reporting high and low levels of smoking-specific social support were significant (at the 10% level). Similar results emerged in the second moderator analysis that predicted biochemically verified point prevalence at T2 (see Table 3 , first column).","[3.0, 5.0, 4.0, 3.0]",Psychology,train,3.75,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.jpeds.2017.10.028,Psychology_22,The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.,"Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","[5.0, 5.0, 3.0]",Psychology,train,4.333333333333333,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1016/j.jpeds.2017.10.028,Psychology_220,Differences in opinions on spanking also differ across ethnic groups and educational backgrounds.,"Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96).","Although the research has some limitations that should caution our interpretation of the findings, the study adds to the substantial amount of research on the problems associated with using spanking as a discipline strategy. Differences in opinions on spanking also differ across ethnic groups and educational backgrounds. As a psychologist, I find this to be a frequent topic of conversation and debate with parents.","Participants were Hispanic (32.6%), white (28.8%), African American (26.0%), and other (12.7%). Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","[1.0, 2.0, 1.0, 3.0, 1.0]",Psychology,train,1.6,news,http://ct.moreover.com/?a=32818256385&p=1pl&v=1&x=0ZAEkx105k29I5f3n6_nlQ
10.1016/j.jalz.2018.06.2856,Psychology_221,"That number is expected to rise to 131.5 million by 2050, the researchers estimate.","In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not.","""What we found was not subtle,"" said Paul Crane, a professor of medicine at the university. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" That number is expected to rise to 131.5 million by 2050, the researchers estimate.","Finally, our study only evaluated the temporal sequence that starts with ophthalmic conditions followed by AD and not vice-versa thus we are unable to assess whether increased risk for ophthalmic conditions may exist in individuals with AD. In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not. Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat.","[1.0, 1.0, 2.0, 1.0, 1.0]",Psychology,train,1.2,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1001/jamapsychiatry.2018.1941,Psychology_222,"Specifically targeting this part of the brain with treatments, the study authors say, could lead to some major progress being made.","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant.","Getting to the bottom of exactly what's going on will require more research, but one of the more promising avenues to explore is the role of the lateral orbitofrontal cortex. Specifically targeting this part of the brain with treatments, the study authors say, could lead to some major progress being made. In this particular case, the researchers say, scientists might be able to discover ways of helping those experiencing problems with depression to get a better night's rest.","Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality. Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","[1.0, 3.0, 2.0, 4.0, 1.0]",Psychology,train,2.2,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1007/s13524-014-0321-x,Psychology_223,"""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.",A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth .,"Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","These might explain why women anticipate a first birth more than men, with stronger happiness increases prior to and around the birth and a larger drop afterward. A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth . Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms.","[3.0, 1.0, 3.0, 3.0]",Psychology,train,2.5,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_224,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,A link positively correlated with the Depressive Problems score indicates that the functional connectivity of that link is positively correlated with the Depressive Problems score.,"The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","The amygdala is not included as a separate area in the Shen atlas, but does have FC related to sleep quality as shown here. A link positively correlated with the Depressive Problems score indicates that the functional connectivity of that link is positively correlated with the Depressive Problems score. The functional connectivities of the lateral orbitofrontal cortex areas (OFClat, OFClat2, and Frontal_Inf_Orb2) were especially related to depression, in that removing the 92 participants who had ever been diagnosed with depression (leaving the column headed 'Participants who had never been diagnosed with depression') decreased the absolute value of the correlations by 0.036, whereas this removal decreased the correlation for the other functional connectivity links by only 0.023 (p=0.053)","[1.0, 3.0, 3.0]",Psychology,train,2.333333333333333,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1177/0956797617692041,Psychology_225,Having to get refills did not seem to deter participants: People were just as likely to buy a large single serving as they were a somewhat smaller serving with refills.,"For the large drink (the only size that the refill manipulation applied to), consumption differed by service style, F(2, 138) = 11.69, p < .001.","However, it did not affect the further downstream behavior of consumption. Having to get refills did not seem to deter participants: People were just as likely to buy a large single serving as they were a somewhat smaller serving with refills. Importantly, most of the people who chose to buy the drink with refills did end up getting a refill, and they tended to consume more overall: Participants consumed 44% more calories when they had a drink with refills than when they had a larger single drink.","Follow-up tests revealed that for the medium drink, consumption was similar across service styles, F(2, 197) = 1.07, p = .34. For the large drink (the only size that the refill manipulation applied to), consumption differed by service style, F(2, 138) = 11.69, p < .001. Specifically, the participants consumed 51.9% more calories in the waiterservice condition than in the typical-portion condition (waiter-service: M = 210.75 kcal, SD = 83.92; typical portion: M = 138.72 kcal, SD = 37.97), t(93) = 5.33, p < .001, d = 1.09.","[3.0, 3.0, 2.0, 2.0]",Psychology,train,2.5,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1016/j.jalz.2018.06.2856,Psychology_226,That's a correlation that's well worth investigating further.,"Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat.","The new study took place across five years, covering 3,877 patients aged 65 and over, and found that those with specific degenerative eye diseases were 40-50 percent more likely to develop Alzheimer's too. That's a correlation that's well worth investigating further. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss.""","In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not. Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat. Supplementary data related to this article can be found at https://doi.org/10.1016/j.jalz.2018.06.2856.","[4.0, 2.0, 2.0]",Psychology,train,2.6666666666666665,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1111/cdep.12038,Psychology_227,"In addition, children who are spanked are at significantly greater risk of being physically abused.","But there is a third reason not to spank our children, and that is a moral one.","In fact, children who are spanked tend to become more aggressive over time, not less. In addition, children who are spanked are at significantly greater risk of being physically abused. The mothers' average age was 34.","We thus have research-based and humanrights-based reasons for not spanking our children. But there is a third reason not to spank our children, and that is a moral one. By using the euphemistic term spanking, parents feel justified in hitting their children while not acknowledging that they are, in fact, hitting.","[3.0, 3.0, 3.0, 3.0]",Psychology,train,3.0,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1111/cdev.12250,Psychology_228,"But over the course of the next two years, from the time they were age 13 to when they turned 15, these ""cool"" kids' social status drastically declined, as shown in the graph below: Allen et al.","Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular"").","In other words, their peers were more likely to say that they saw them as ""mature"" with ""high social status"" and therefore a ""desirable companion"" to spend time with. But over the course of the next two years, from the time they were age 13 to when they turned 15, these ""cool"" kids' social status drastically declined, as shown in the graph below: Allen et al. By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset.","This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed. Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular""). The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers.","[3.0, 2.0, 2.0]",Psychology,train,2.333333333333333,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1038/s41598-018-30980-y,Psychology_229,"The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day.","This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues. This delay may reflect ""short-term destabilization of an enriched memory,"" they add.","Change in memory accuracy also did not differ when probed after a nap compared to the change in memory accuracy after an interval awake. However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap.","[5.0, 3.0, 3.0, 3.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1016/j.jpeds.2017.10.028,Psychology_23,The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.,"Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59).","About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","[5.0, 5.0, 3.0]",Psychology,train,4.333333333333333,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1038/s41598-018-30980-y,Psychology_230,"This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children.""","Given that ΔRecall nap significantly predicted ΔRecall overnight , and both significantly predicted by nap SWA, the preliminary conditions for a mediation analysis were met.","A significant benefit of napping was observed only when changes across the entire 24-hour period were considered. This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","In other words, overnight SWS predicted improved memory performance when a nap rich in SWA had occurred earlier in the day. Given that ΔRecall nap significantly predicted ΔRecall overnight , and both significantly predicted by nap SWA, the preliminary conditions for a mediation analysis were met. When nap SWA was controlled for, the standardized regression coefficient for the relationship between ΔRecall nap and ΔRecall overnight was reduced from B = −0.488, (p = 0.029) to B = −0.364 (p = 0.182).","[4.0, 3.0, 3.0, 4.0, 4.0]",Psychology,train,3.6,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_231,The happiness level of parents varied among different ages.,"However, when the question is how children influence parental well-being, it is important to analyze individual changes over time instead of only comparing parents with the childless.","On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.","These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing. However, when the question is how children influence parental well-being, it is important to analyze individual changes over time instead of only comparing parents with the childless. Otherwise, the analyses may be biased by genetic factors, personality, or other unobserved or difficult-to-measure fixed characteristics, such as orientation toward career versus family, which may be associated with both fertility behavior and subjective wellbeing .","[1.0, 4.0, 3.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1177/0141076814565942,Psychology_232,The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"and describe feelings, and our findings suggest that circumcision may somehow trigger the development of ASD in a small fraction of young boys.","The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. While it is unacceptable today to circumcise boys without proper pain relief, there is no way to eliminate the pain completely, the researchers said, adding that some boys will endure a lot of pain.","Reassuringly, 6 out of 99 ASD diagnoses (97%) in children born 1990-1999 and recorded in the Danish Psychiatric Central Register, the source of psychiatric data in the National Patient Register, were confirmed upon medical chart review. and describe feelings, and our findings suggest that circumcision may somehow trigger the development of ASD in a small fraction of young boys. These findings obviously do not prove the suggested associations.","[4.0, 2.0, 5.0, 3.0]",Psychology,train,3.5,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1073/pnas.1505114112,Psychology_233,"But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life.","Consistent with the known developmental trajectory of the cortical onset response, there was an increase in the difference between N1 and P1 from year 1 to year 4 for the music group [t(16) = 2.22, P = 0.041, partial eta squared = 0.24].","The findings have important implications for teens in low-income neighborhoods, as their language development is often below that of their wealthier counterparts. But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life. Source: Tierney A, Krizman J, Kraus N. Music training alters the course of adolescent auditory development.","Although the two groups did not differ at year 1 (P > 0.2), in year 4, the music training group had higher response consistency than the JROTC group [t(36) = 2.62, P = 0.013, partial eta squared = 0.16]. Consistent with the known developmental trajectory of the cortical onset response, there was an increase in the difference between N1 and P1 from year 1 to year 4 for the music group [t(16) = 2.22, P = 0.041, partial eta squared = 0.24]. The relationship between N1 and P1, however, did not change for the JROTC group [P > 0.1, year-by-training group interaction, F(1,34) = 6.41, P = 0.016, partial eta squared = 0.159] (Fig.","[2.0, 3.0, 4.0, 1.0, 3.0]",Psychology,train,2.6,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1111/cdev.12250,Psychology_235,"At the onset of the study, about 20% of the subjects were considered ""cool.""","Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular"").","Similarly, the average family range of annual income was just under $52,000 in 2013. At the onset of the study, about 20% of the subjects were considered ""cool."" In other words, their peers were more likely to say that they saw them as ""mature"" with ""high social status"" and therefore a ""desirable companion"" to spend time with.","This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed. Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular""). The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers.","[3.0, 3.0, 2.0, 5.0]",Psychology,train,3.25,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1001/jamapsychiatry.2018.1941,Psychology_236,"Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""",We note that the causal relations between sleep and depression is an important topic that deserves much further investigation.,"The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments."" So, whatever it is you're going through, remember you're not alone.","Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis. We note that the causal relations between sleep and depression is an important topic that deserves much further investigation. Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants.","[3.0, 3.0, 1.0]",Psychology,train,2.333333333333333,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1001/jamapsychiatry.2018.1941,Psychology_237,The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep.,This cross-validation analysis thus provides evidence that the sleep-related links described here can be confirmed with an independent dataset.,"Results showed that 162 functional connectivity links in the brain were connected with our ability (or lack of) to get some shut-eye; of these, 39 were also linked to depressive problems a such as low self-esteem, low mood, and a lack of motivation. The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""","Further, we found that 89 out of the 162 significant links were also significant after FDR correction (p<0.05) in the Biobank dataset. This cross-validation analysis thus provides evidence that the sleep-related links described here can be confirmed with an independent dataset. The mean strength of the 39 significant functional connectivities shown in Fig.","[2.0, 4.0, 3.0, 4.0, 2.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1007/s13524-014-0321-x,Psychology_238,"""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.",This pattern is consistent with the fertility behavior that emerged during the second demographic transition and provides new insights into low and late fertility.,"There was a 50 percent decrease in happiness during the birth of a second child, followed by a total slump by the time the third child is born. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings. Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources.","The results, which are similar in Britain and Germany, suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing. This pattern is consistent with the fertility behavior that emerged during the second demographic transition and provides new insights into low and late fertility. Beyond the individual, social learning about the parental well-being trajectories of others may influence the quantum and tempo of fertility.","[3.0, 3.0, 1.0, 1.0]",Psychology,train,2.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1093/jcr/ucw012,Psychology_239,"While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.","Finally, we suggest that the adjustments to self-perceptions produced by behaviorally targeted ads may not only improve sales of the featured product at the time of ad exposure, but also future sales of the product and, potentially, of the entire category.","""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them. ""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said.","This is likely easier to accomplish for lifestyle brands and brands with strong personalities . Finally, we suggest that the adjustments to self-perceptions produced by behaviorally targeted ads may not only improve sales of the featured product at the time of ad exposure, but also future sales of the product and, potentially, of the entire category. Specifically, when consumers accept the label they infer from a behaviorally targeted ad, the extent to which they use these self-perceptions as a basis for making a purchase decision increases.","[3.0, 4.0, 4.0, 4.0]",Psychology,train,3.75,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1001/jamapsychiatry.2018.1941,Psychology_24,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,"The brain areas with increased functional connectivity associated with both sleep and Depressive Problems scores included the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, anterior and posterior cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","Of these links, 39 were also associated with the Depressive Problems scores. The brain areas with increased functional connectivity associated with both sleep and Depressive Problems scores included the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, anterior and posterior cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus. A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001).","[4.0, 5.0, 1.0, 3.0, 2.0]",Psychology,train,4.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1093/jcr/ucw012,Psychology_240,"""If people don't see the trait implied by an ad as negative, our research suggests that they would see themselves as having the trait to a greater extent,"" she says.","We propose that the effects of a social label implied by a behaviorally targeted ad are akin to informing a consumer of their revealed preferences (based on past choices that are affected by the external environment), and those of identity priming are akin to reminding a consumer of their stated preferences (generated from accessing internal information).","Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner. ""If people don't see the trait implied by an ad as negative, our research suggests that they would see themselves as having the trait to a greater extent,"" she says. If online advertisements have the power to reshape a person's image of themselves, as that last Ohio State study suggests, it may be time to stop thinking about the internet as something people use, and start thinking of it as a new environment in which human beings exist and adapt, for better or worse.","The notion of revealed preferences parallels that of constructed preferences, which are constructed on the fly as a result of the interaction between the (internal) properties of the human decision making system and the (external) properties of the environment in which a decision is made . We propose that the effects of a social label implied by a behaviorally targeted ad are akin to informing a consumer of their revealed preferences (based on past choices that are affected by the external environment), and those of identity priming are akin to reminding a consumer of their stated preferences (generated from accessing internal information). Consumers therefore receive information about what others (i.e., the marketer) think about them (based on observing their choices and other past behavior) when they receive a behaviorally targeted ad, a process distinct from making an identity salient because it involves an external indication that one has a trait or set of traits.","[4.0, 4.0, 4.0, 1.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1073/pnas.1505114112,Psychology_241,"The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment.",The two training groups did not differ on rapid naming score at year 1 (P > 0.2).,"The findings suggest that music instruction helps enhance skills that are critical for academic success. The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment. ""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" says Nina Kraus, senior study author and director of the Auditory Neuroscience Laboratory at Northwestern University.","3 ) and no main effects (P > 0.2). The two training groups did not differ on rapid naming score at year 1 (P > 0.2). Although adolescents undergoing JROTC training exhibited the typical waning of the consistency of the subcortical response to speech , music training maintained high response consistency throughout high school.","[1.0, 3.0, 1.0, 2.0]",Psychology,train,1.75,news,http://www.theepochtimes.com/n3/1677179-band-class-helps-teens-learn-how-learn/
10.1111/cdev.12370,Psychology_242,"""These results show that teens can use self-distancing strategies in much the same way as adults,"" White notes.",Future research is needed to explore the association between self-distancing and other negative emotions in adolescence.,"Older youth who self-distanced became even less upset than younger adolescents who did so. ""These results show that teens can use self-distancing strategies in much the same way as adults,"" White notes. ""They also suggest that the teen years could be critical in developing this way to regulate emotions.""","Importantly, our data suggest that even without forgiveness, placing less blame on others can be adaptive. Future research is needed to explore the association between self-distancing and other negative emotions in adolescence. Given the increasing prevalence of psychopathology across adolescence (e.g., , it will be important to evaluate the role of psychological distancing on emotion regulation in clinical populations.","[3.0, 2.0, 2.0, 2.0]",Psychology,train,2.25,news,http://www.sciencedaily.com/releases/2015/04/150415092801.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1093/jcr/ucw012,Psychology_243,"""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","The implications may be broader, however, because receipt of the ad can imply that one is viewed as a specific type of person.","One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.","Most directly, receipt of the ad signifies that one is expected to like the featured product. The implications may be broader, however, because receipt of the ad can imply that one is viewed as a specific type of person. When one recognizes an external characterization of one's identity in this way, we predict that consumers adjust both their self-perceptions and behavior to be consistent with the implied label.","[2.0, 2.0, 3.0, 2.0]",Psychology,train,2.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/s41598-018-30980-y,Psychology_244,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","Notably, here too with emotional memories, we found a significant association between ΔRecall nap and ΔRecall overnight such that declines in accuracy across the nap were associated with improvements across overnight sleep (B = −0.488, p = 0.029; 95% CI: [−1.294, −0.079]; Fig.","Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.","In that study, ΔRecall nap predicted ΔRecall overnight , suggesting an interaction of multiple sleep bouts on memory processing. Notably, here too with emotional memories, we found a significant association between ΔRecall nap and ΔRecall overnight such that declines in accuracy across the nap were associated with improvements across overnight sleep (B = −0.488, p = 0.029; 95% CI: [−1.294, −0.079]; Fig. We did not receive caregiver reports for 9 of the children.","[4.0, 4.0, 4.0, 2.0, 4.0]",Psychology,train,3.6,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jamapsychiatry.2018.1941,Psychology_246,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","An analysis of the records of 9,735 people living with depressive problems found that there was increased activity between these brain regions in people who also reported disrupted sleep patterns, and that's a crucial discovery in our understanding of these conditions. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" From the other side, people with insomnia also have a higher risk of depression and anxiety.","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","[4.0, 5.0, 5.0, 5.0, 5.0]",Psychology,train,4.8,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1007/s13524-014-0321-x,Psychology_247,"Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child.",A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth .,"Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses."" Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child. Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain.","These might explain why women anticipate a first birth more than men, with stronger happiness increases prior to and around the birth and a larger drop afterward. A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth . Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms.","[3.0, 2.0, 5.0, 4.0, 4.0]",Psychology,train,3.6,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/lcrp.12013,Psychology_248,"Although closing your eyes to remember seems to work whether or not rapport has been built beforehand, our results show that building rapport makes witnesses more at ease with closing their eyes.",", it is perhaps not surprising that eye-closure was particularly effective during the second session.","""It is clear from our research that closing the eyes and building rapport help with witness recall. Although closing your eyes to remember seems to work whether or not rapport has been built beforehand, our results show that building rapport makes witnesses more at ease with closing their eyes. That in itself is vital if we are to encourage witnesses to use this helpful technique during interviews,"" said Dr. Robert Nash, lead author of the study.","In light of participants' decreased recall performance after the intervening 1-week delay (cf. , it is perhaps not surprising that eye-closure was particularly effective during the second session. Nevertheless, we did not anticipate a null effect of eye-closure during the first free-recall attempt.","[3.0, 4.0, 3.0, 4.0, 3.0]",Psychology,train,3.4,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1001/jamapsychiatry.2018.1941,Psychology_25,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001).,"In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","The brain areas with increased functional connectivity associated with both sleep and Depressive Problems scores included the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, anterior and posterior cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus. A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.","[5.0, 5.0, 5.0, 3.0]",Psychology,train,4.5,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1007/s13524-014-0321-x,Psychology_250,Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.,"Similarly, given that we find no positive gain in subjective well-being for third births, the documented differences by parity may help explain the low quantum of fertility.","Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children. Younger parents, on the other hand, are more prone to post-birth depression.","The fact that among older and better-educated parents, well-being increases with childbearing, but that young and less-educated parents have flat or even downward happiness trajectories, may explain why postponing fertility has become so common. Similarly, given that we find no positive gain in subjective well-being for third births, the documented differences by parity may help explain the low quantum of fertility. These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing.","[1.0, 5.0, 1.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1001/jamapsychiatry.2018.1941,Psychology_251,"The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep.",IMPORTANCE Depression is associated with poor sleep quality.,"The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep. This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[3.0, 2.0, 3.0, 4.0, 3.0]",Psychology,train,3.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1016/j.jalz.2018.06.2856,Psychology_252,"""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine.",Several factors suggest the effects we found are specific to these ophthalmic conditions and not merely agerelated phenomena.,"Cataract diagnosis was not an Alzheimer's disease risk factor. ""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye.""","First, it may seem tempting to dismiss these findings as age-related phenomena. Several factors suggest the effects we found are specific to these ophthalmic conditions and not merely agerelated phenomena. Our specific findings also mitigate the possibility that they merely reflect age-related phenomena.","[1.0, 1.0, 1.0, 2.0, 1.0]",Psychology,train,1.2,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1001/jamapsychiatry.2018.3514,Psychology_253,"The research shows that this dysfunction can predict suicidal behaviour, and offers new prospects for treatment and suicide prevention.","Individuals who reported PEs had a 4.39-fold (95% CI, 1.63-11.78) increased odds of suicide death (Figure 2 ).","The research shows that this dysfunction can predict suicidal behaviour, and offers new prospects for treatment and suicide prevention. Such episodes are not necessarily associated with psychotic illnesses or depression and can occur in people who do not experience mental illness, according to the study. Dr Ian Kelleher, RCSI Psychiatry Research Lecturer and study lead, commented: ""Our research shows that if we can understand and treat the factors associated with these perceptual abnormalities, we could prevent at least a quarter of suicide attempts and deaths.","Individuals who reported PEs had a 3.15-fold (95% CI, 2.23-4.45) increased odds of suicide attempt. Individuals who reported PEs had a 4.39-fold (95% CI, 1.63-11.78) increased odds of suicide death (Figure 2 ). The population-attributable fraction of PEs for suicidal ideation was 11.9%.","[5.0, 2.0, 3.0, 3.0, 2.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=37828547572&p=1pl&v=1&x=0DCeKj2mrndVr_6QSdn9XA
10.1111/cdev.12250,Psychology_255,"Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.",One potential explanation for these findings is provided by cumulative continuity theory .,"""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study. One thing to note is that this was a relatively small study.","In terms of competence with peers, pseudomature behavior in early adolescence predicted not only declining popularity with peers across adolescence but also lower levels of peer competence, as rated by peers, in early adulthood. One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","[2.0, 4.0, 1.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1093/jcr/ucw012,Psychology_256,One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.,"When their past behavior is not at all indicative of the label (i.e., the behavioral targeting is inaccurate), consumers do not treat the implied label as a valid source of self-information and do not alter their self-perceptions to be consistent with the label.","For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","Importantly, however, we find that adjustments in consumer self-perceptions in response to behaviorally targeted advertisements depend on the plausibility of the connection between the label and past behavior. When their past behavior is not at all indicative of the label (i.e., the behavioral targeting is inaccurate), consumers do not treat the implied label as a valid source of self-information and do not alter their self-perceptions to be consistent with the label. Our findings offer several important theoretical contributions.","[4.0, 2.0, 3.0]",Psychology,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1016/j.jpeds.2017.10.028,Psychology_257,"Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence.",Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth.,"There was a positive relationship between corporal punishment and physical violence during a romantic relationship. Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence. These results remained even when the team accounted for the number of children who experienced child abuse, which is described as any form of punishment that is inappropriate or causes series injury.","(J Pediatr 2018;194:233-7). Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth. 9 These factors cut across various domains including affective (eg, emotion dysregulation, psychiatric disorder), cognitive (eg, attitudes toward women, beliefs about violence), demographic (eg, age, race, sex, sexual orientation, socioeconomic status), interpersonal (eg, relationship satisfaction, problem solving skills), contextual (eg, availability of weapon, drug/alcohol use), as well as distal factors (eg, history of child abuse, exposure to family violence).","[5.0, 4.0, 3.0, 1.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1111/cdep.12038,Psychology_258,"Given the wide acceptance of parental corporal punishment in the United States, it seems important to highlight these findings again.","Rather, spanking predicted increases in children's aggression over and above initial levels.","If these findings sound familiar, it's because Holden collected the data for this study a couple of years ago and publicly reported on them at that time. Given the wide acceptance of parental corporal punishment in the United States, it seems important to highlight these findings again. Overwhelming evidence

It's actually quite stunning that any parent today would use corporal punishment when the evidence overwhelmingly shows that this form of discipline is harmful, not helpful, to a child's development.","In these studies, although children's aggressive behavior often elicited more spanking over time, this effect did not entirely explain the association between spanking and children's aggression. Rather, spanking predicted increases in children's aggression over and above initial levels. Spanking consistently predicted increases in children's aggression over time, regardless of how aggressive children were when the spanking occurred.","[1.0, 3.0, 3.0, 3.0]",Psychology,train,2.5,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1111/cdev.12250,Psychology_259,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","For parents and others working with adolescents, the critical point is not that the pseudomature behaviors observed are fundamentally pathological-to the contrary, romantic involvement becomes normative and healthy later in adolescence, and most adolescents engage in at least some degree of minor delinquent behavior.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","This research has found that sexual behavior that occurs in late adolescence reflects biological and psychosocial maturity and is distinguishable from earlier sexual activity that appears driven by less adaptive processes and that is associated with less adaptive outcomes (ZimmerGembeck & Helfand, 2008) . For parents and others working with adolescents, the critical point is not that the pseudomature behaviors observed are fundamentally pathological-to the contrary, romantic involvement becomes normative and healthy later in adolescence, and most adolescents engage in at least some degree of minor delinquent behavior. Rather, it is that engaging in these behaviors very early in adolescence, and as an apparent means of seeking peer status, is a significant marker of future risk.","[3.0, 3.0, 3.0, 2.0, 3.0]",Psychology,train,2.8,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1001/jamapsychiatry.2018.1941,Psychology_26,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,"Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","The results show that both poor sleep quality and depressive problems are significantly positively correlated with functional connectivities involving the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the cingulate cortex, and the precuneus. Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality. Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant.","[5.0, 5.0, 4.0, 4.0, 3.0]",Psychology,train,4.2,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1093/jcr/ucw012,Psychology_260,"""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","Specifically, we show that mere receipt of a behaviorally targeted ad can cause consumers to recognize that the marketer has labeled them as a particular type of consumer, even when the ad itself contains no descriptive information about the individual consumer.","One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.","In addition, our work contributes to the literature on social labeling by introducing a new type of implied social label. Specifically, we show that mere receipt of a behaviorally targeted ad can cause consumers to recognize that the marketer has labeled them as a particular type of consumer, even when the ad itself contains no descriptive information about the individual consumer. In doing so, we contribute to the literature by demonstrating that labels do not have to reference the consumer to have an effect (as has been shown in past research), but that consumers can be affected by implied labels supplied by external sources.","[4.0, 2.0, 2.0, 3.0, 1.0]",Psychology,train,2.4,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1093/chemse/bjt066,Psychology_263,The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels.,"Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label.","When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.","In summary, odor labels affect pleasantness ratings and edibility perception. Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label. Odors with different valences impact our mood and wellbeing in different ways.","[5.0, 4.0, 3.0, 3.0]",Psychology,train,3.75,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Psychology_266,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births.","In the FE model for the German data, we also observe an increase in happiness two to three years before the birth.","The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births. The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.","The main difference between the OLS and the FE models is that the happiness increase in the years preceding birth and in the year of birth is somewhat stronger in the FE specification, and the decrease in post-birth decline is not quite as strong in the FE specification. In the FE model for the German data, we also observe an increase in happiness two to three years before the birth. Such anticipation effects are not surprising because the process of childbearing from planning to birth may take years.","[2.0, 4.0, 2.0, 2.0, 1.0]",Psychology,train,2.2,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Psychology_267,"Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child.","Similarly, given that we find no positive gain in subjective well-being for third births, the documented differences by parity may help explain the low quantum of fertility.","Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses."" Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child. Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain.","The fact that among older and better-educated parents, well-being increases with childbearing, but that young and less-educated parents have flat or even downward happiness trajectories, may explain why postponing fertility has become so common. Similarly, given that we find no positive gain in subjective well-being for third births, the documented differences by parity may help explain the low quantum of fertility. These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing.","[1.0, 1.0, 1.0, 1.0, 3.0]",Psychology,train,1.4,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_27,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior. In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways. Each of these behaviorsminor deviance, a focus on physical appearance in choosing friends, and precocious romantic activityis clearly distinct, yet each shares in common the potential to provide a veneer of maturity to the early adolescent seeking to enhance status with his or her peers.","[4.0, 4.0, 3.0, 4.0]",Psychology,train,3.75,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1073/pnas.1505114112,Psychology_271,These findings suggest that musical training could keep that window open longer.,We show that in-school music training changes the course of adolescent brain development.,"At the end of 3 years, those students who had played instruments were better at detecting speech sounds, like syllables and words that rhyme, than their JROTC peers, the team reports online today in the Proceedings of the National Academy of Sciences. These findings suggest that musical training could keep that window open longer. But the benefits of music aren't just for musicians; taking up piano could be the difference between an A and a B in Spanish class.","Moreover, given that the cortical N1 onset response emerges during adolescence while the P1 response declines , and that We show that in-school music training changes the course of adolescent brain development. Relative to an active control group that shows the expected wane in subcortical response consistency, adolescents undertaking in-school music training maintained heightened neural consistency throughout high school.","[3.0, 4.0, 4.0, 2.0, 5.0]",Psychology,train,3.6,news,http://news.sciencemag.org/brain-behavior/2015/07/benefits-band-class
10.1038/s41598-017-03627-7,Psychology_272,"""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein.","It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 .","The more physiologically synchronized they were, the less pain she felt. ""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein. Further research is necessary to figure out precisely how a partner's touch eases pain.","This complicated physiological mechanism may underlie the observed coupling between the partners. It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 . Thus, future research should test the role of oxytocin in touch-related analgesia.","[3.0, 4.0, 4.0, 4.0, 5.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1016/j.jpeds.2017.10.028,Psychology_273,"According to Temple, this research is just another study to show the negative impacts of corporal punishment.","Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings.","These results remained even when the team accounted for the number of children who experienced child abuse, which is described as any form of punishment that is inappropriate or causes series injury. According to Temple, this research is just another study to show the negative impacts of corporal punishment. For example, although the fear of being hit can temporarily prevent a child from doing a problematic behavior, in the long run it may have psychological consequences.","This latter concern is tempered by the fact that prevalence of corporal punishment and dating violence in the current population was similar to nationally representative samples. Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence.","[3.0, 1.0, 1.0, 2.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1038/s41598-018-30980-y,Psychology_274,"As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits.""",Note that 2 children were absent for the 24-hr recognition phase but are included in all other analyses.,"Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children."" As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out.","This left a remaining sample of 49 children (30 female; n = 29 classroom, n = 20 laboratory; M = 51.55 months, SD = 7.16, range = 34-64.30 months) in the following analyses. Note that 2 children were absent for the 24-hr recognition phase but are included in all other analyses. Children tested in the laboratory compared to those tested in the classroom did not differ in age (t(47) = −0.688, p = 0.495), nap length (t(47) = 0.370, p = 0.713), or accuracy across any of the recognition phases (all p's greater than 0.200); as such, behavioral data was collapsed to increase power.","[3.0, 1.0, 1.0, 1.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1093/jcr/ucw012,Psychology_275,"For example, in one experiment, people felt more environmentally conscious after they received a behaviorally targeted ad for a ""green"" product.",The results of study 3 replicate previous results by showing that ads identified as behaviorally targeted can affect consumer self-perceptions and hence behavior.,"For example, in one experiment, people felt more environmentally conscious after they received a behaviorally targeted ad for a ""green"" product. ""The power of a behaviorally targeted ad for a green product isn't just that it persuades you to buy the advertised product. It actually makes you feel more environmentally conscious and can change your behavior,"" said Rebecca Walker Reczek, co-author of the study and associate professor of marketing at The Ohio State University's Fisher College of Business.",", and this effect was not present when the order of the mediators was reversed (b ¼ .0046, SE ¼ .02, 95% CI, À.0297 to .0607). The results of study 3 replicate previous results by showing that ads identified as behaviorally targeted can affect consumer self-perceptions and hence behavior. Specifically, consumers receiving a behaviorally targeted ad for an environmentally friendly ""green"" product viewed themselves as possessing stronger green consumption values.","[5.0, 4.0, 3.0, 4.0, 4.0]",Psychology,train,4.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1073/pnas.1509654112,Psychology_276,"But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains.",The size of each circle is proportional to the percent of individuals from the same sex/gender category with an identical score on the two measures.,"They found 29 regions that seem to be different sizes in people who identified as male or female. But things got interesting when they took a look at the individual brain scans: Only zero to eight percent of people had an aEURoeall maleaEUR or aEURoeall femaleaEUR brain, meaning most people have a mix of elements that are classified as both male and female in their brains. While itaEUR(tm)s possible to have predominantly female components or predominantly male components to your brain, researchers found that most people are in the middle.",Another noteworthy observation is that the size of the sex/gender Fig. The size of each circle is proportional to the percent of individuals from the same sex/gender category with an identical score on the two measures. difference in some regions varied considerably between different datasets (Table S1 ).,"[1.0, 2.0, 1.0]",Psychology,train,1.3333333333333333,news,http://healthmedicinet.com/news/science-proves-men-and-women-are-actually-from-the-same-planet/
10.1038/s41598-018-30980-y,Psychology_277,"This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children.""","Supporting an interaction across sleep bouts, SWA in the nap negatively predicted ΔRecall nap (B = −0.601, p = 0.008; 95% CI: [−2.982, −0.517]; Fig.","A significant benefit of napping was observed only when changes across the entire 24-hour period were considered. This supports an interplay between the nap and subsequent overnight sleep in the consolidation of memories in young children."" The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues.","In light of the reduced accuracy across the nap predicting improvements in accuracy overnight (Fig. Supporting an interaction across sleep bouts, SWA in the nap negatively predicted ΔRecall nap (B = −0.601, p = 0.008; 95% CI: [−2.982, −0.517]; Fig. 3B ) and positively predicted ΔRecall overnight (B = 0.518, p = 0.028; 95% CI: [0.000, 0.005]; Fig.","[3.0, 1.0, 4.0, 1.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_278,Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.,"First, if we observe that young parents have negative well-being trajectories but that older parents with more resources have easier transitions to parenthood, this may influence postponement of a first birth through social learning.","Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Beyond the individual, social learning about the parental well-being trajectories of others may influence the quantum and tempo of fertility. First, if we observe that young parents have negative well-being trajectories but that older parents with more resources have easier transitions to parenthood, this may influence postponement of a first birth through social learning. Second, if we observe the transition to parenthood being accompanied by negative rather than positive changes in well-being, this can lead to lower fertility intentions, lower realized fertility, and also postponement if one surmises that less time is needed to have a smaller optimal number of children.","[2.0, 3.0, 3.0]",Psychology,train,2.6666666666666665,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/s13229-018-0246-0,Psychology_28,"""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","Conclusions: Results from Jilin City, where both mainstream and special school data were available, revealed a similar prevalence of autism in China to the West, at around 1%.","In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China. We have been able to use a standardized screening methodology, allowing us to compare the results with Western countries to show that autism occurs broadly at the same rate, irrespective of culture.""","In Jiamusi City, 16,358 children were screened, with 10 autism cases being identified, with a mainstream prevalence of 19 per 10,000 (95% CI 10-38). Conclusions: Results from Jilin City, where both mainstream and special school data were available, revealed a similar prevalence of autism in China to the West, at around 1%. Results from Shenzhen and Jiamusi cities, where only mainstream data were available, prevalence is also in line with Western estimates.","[2.0, 2.0, 5.0, 2.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1111/cdev.12250,Psychology_280,"""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said.","The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers.","By 22, the cool kids struggled to make friends. ""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.","Early reliance upon minor acts of delinquency to impress peers may thus lead to a greater likelihood of associating with deviance-prone peers, who in turn would only be impressed by more and more serious acts of deviance over time. The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers. Similarly, whereas minor levels of alcohol or substance use may impress a subgroup of peers in early adolescence, by early adulthood, such behavior would gain little notice, and it may take heavy drinking and more serious substance use to try to impress adult peers.","[1.0, 2.0, 2.0, 2.0, 2.0]",Psychology,train,1.8,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1038/s41598-018-30980-y,Psychology_281,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.","However, experimenters did rate children as significantly more sleepy in the nap condition after both Memory Performance.","However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","Experimenter ratings of mood also did not differ across conditions. However, experimenters did rate children as significantly more sleepy in the nap condition after both Memory Performance. Contrary to the findings of Kinzler and Shutts , across conditions there were no significant differences between immediate recognition accuracy of negative and positive stimuli (F(1,48) = 0.02, p = 0.865).","[4.0, 3.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1111/cdev.12250,Psychology_283,"Ironically, the kids who seemed to have it all at age 13 -- popularity, invites to parties, older friends, and love lives -- are the ones who ""didn't turn out O.K.""","In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways.","Some, however, appear to completely miss the boat. Ironically, the kids who seemed to have it all at age 13 -- popularity, invites to parties, older friends, and love lives -- are the ones who ""didn't turn out O.K."" The reason these ""cool"" kids are lost at sea as adults isn't karma working its magic -- it's more scientific than that.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior. In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways. Each of these behaviorsminor deviance, a focus on physical appearance in choosing friends, and precocious romantic activityis clearly distinct, yet each shares in common the potential to provide a veneer of maturity to the early adolescent seeking to enhance status with his or her peers.","[2.0, 2.0, 1.0, 1.0, 4.0]",Psychology,train,2.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1007/s13524-014-0321-x,Psychology_284,"Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.","Those who have children at older ages or who have more education have a particularly positive happiness response to a first birth; and although having the first two children increases happiness, having a third child does not.","The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness. A first-born child brought the most happiness, no matter what age the parents were.","Sociodemographic factors strongly modify this pattern. Those who have children at older ages or who have more education have a particularly positive happiness response to a first birth; and although having the first two children increases happiness, having a third child does not. The results, which are similar in Britain and Germany, suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing.","[4.0, 3.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1007/s13524-014-0321-x,Psychology_285,"""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution.","""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings. Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources.","If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced. Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution. However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births.","[2.0, 1.0, 2.0]",Psychology,train,1.6666666666666667,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_286,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior. In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways. Each of these behaviorsminor deviance, a focus on physical appearance in choosing friends, and precocious romantic activityis clearly distinct, yet each shares in common the potential to provide a veneer of maturity to the early adolescent seeking to enhance status with his or her peers.","[1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1093/jcr/ucw012,Psychology_287,"For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad.","Behavioral targeting may, therefore, be a way for marketers to circumvent consumers' feelings of reactance to explicit identity referencing in advertising because such labels are merely implied versus explicit.","If an ad makes you feel sophisticated or environmentally conscious, you are more likely to engage in all kinds of behaviors related to that trait - not just buy the advertised product,"" Reczek said. For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.","Further, while much research within the identity literature has investigated the effects of identity appeals that are embedded within the advertising context and are unconsciously processed ), the results of our studies show that a key driver of the effects of behaviorally targeted advertising is consumers' conscious reflection about the marketers' tactics in delivering the ad to them. Behavioral targeting may, therefore, be a way for marketers to circumvent consumers' feelings of reactance to explicit identity referencing in advertising because such labels are merely implied versus explicit. Our findings also have implications for managers because we find that consumer responses to behaviorally targeted ads are sensitive to several variables under managerial control.","[2.0, 1.0, 2.0, 4.0]",Psychology,train,2.25,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1073/pnas.1505114112,Psychology_288,The findings suggest that music instruction helps enhance skills that are critical for academic success.,"Phonological awareness improved in both training groups from year 1 to year 4, but these gains were larger in the adolescents who underwent in-school music training.","The findings suggest that music instruction helps enhance skills that are critical for academic success. The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment. ""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" says Nina Kraus, senior study author and director of the Auditory Neuroscience Laboratory at Northwestern University.","An increase in the N1/P1 amplitude ratio from year 1 to year 4, known to emerge in adolescence , was observed in the music group but had not yet emerged in the JROTC group. Phonological awareness improved in both training groups from year 1 to year 4, but these gains were larger in the adolescents who underwent in-school music training. Two other language tests, phonological memory and rapid naming, showed no group differences.","[3.0, 4.0, 3.0, 3.0, 4.0]",Psychology,train,3.4,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1007/s13524-014-0321-x,Psychology_289,Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility.,"For third births, the pattern is qualitatively different: there are no positive effects around the birth, and the long-term trajectory is declining; however, the differences compared with second or first births are not significant.","Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources. Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.","For second births, the overall trajectory is similar, but the increase in happiness before and around the birth is lower than for first births (p < .05). For third births, the pattern is qualitatively different: there are no positive effects around the birth, and the long-term trajectory is declining; however, the differences compared with second or first births are not significant. For both men and women, the happiness trajectories surrounding a first birth are very similar, and the differences are statistically not significant across these models.","[2.0, 4.0, 1.0, 2.0, 5.0]",Psychology,train,2.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1016/j.jalz.2018.06.2856,Psychology_290,That's a correlation that's well worth investigating further.,"Thus, the trend we found for AMD could suggest an initial insult propagating degenerative pathways in the eye and brain, in addition to chronic degenerative/inflammatory pathways.","The new study took place across five years, covering 3,877 patients aged 65 and over, and found that those with specific degenerative eye diseases were 40-50 percent more likely to develop Alzheimer's too. That's a correlation that's well worth investigating further. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss.""","Unlike the case for glaucoma, we found that AMD diagnosed proximal to (0-2 years) and further from (0-10 years) the index date had significantly elevated risks for AD (P-values , .001 to .005, Supplementary Table 3 ). Thus, the trend we found for AMD could suggest an initial insult propagating degenerative pathways in the eye and brain, in addition to chronic degenerative/inflammatory pathways. In contrast, similar risk for AD in participants who have DR regardless of its duration suggest that microvascular insults or ischemia found in DR may occur concurrently with the changes in brain associated with diabetes.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1007/s13524-014-0321-x,Psychology_291,This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small.,"The results, which are similar in Britain and Germany, suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing.","""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report. This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small. The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby.","Those who have children at older ages or who have more education have a particularly positive happiness response to a first birth; and although having the first two children increases happiness, having a third child does not. The results, which are similar in Britain and Germany, suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing. This pattern is consistent with the fertility behavior that emerged during the second demographic transition and provides new insights into low and late fertility.","[2.0, 1.0, 2.0, 3.0]",Psychology,train,2.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1111/lcrp.12013,Psychology_292,"""It is clear from our research that closing the eyes and building rapport help with witness recall.","However, if eye-closure were more effective for 'easier' forms of recall, we would have expected it to have a bigger impact on immediate free recall than on delayed free recall, whereas we observed the opposite.","However, participants who had built a rapport said that they felt more comfortable when they closed their eyes. ""It is clear from our research that closing the eyes and building rapport help with witness recall. Although closing your eyes to remember seems to work whether or not rapport has been built beforehand, our results show that building rapport makes witnesses more at ease with closing their eyes.","In light of this difference, an alternative explanation could be that eye-closure improves recall of easy-to-remember, as opposed to difficult-to-remember, information. However, if eye-closure were more effective for 'easier' forms of recall, we would have expected it to have a bigger impact on immediate free recall than on delayed free recall, whereas we observed the opposite. Thus, an explanation of the eye-closure effect based purely on information difficulty does not seem to account well for the findings.","[1.0, 5.0, 5.0, 2.0, 2.0]",Psychology,train,3.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1001/jamapsychiatry.2018.1941,Psychology_293,A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans.,"We found that all 39 links significantly mediated the relationship between the PSQI sleep quality and the depressive problem score (using FDR correction, p<0.05, Table S4 ).","Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","This provides evidence that the 39 functional connectivity links may account for this proportion of the relation of poor sleep quality on depressive problems. We found that all 39 links significantly mediated the relationship between the PSQI sleep quality and the depressive problem score (using FDR correction, p<0.05, Table S4 ). In the reverse direction, only 2 links significantly mediated effects of sleep quality on depressive problems with FDR correction.","[4.0, 5.0, 1.0, 3.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1080/08870446.2013.818674,Psychology_294,"When occurring on their own, self-efficacy, coping strategies and social support did not increase the chances of quitting.","than 1.87, the association between volitional self-efficacy and continuous abstinence was significant (p<.lO).","Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good. When occurring on their own, self-efficacy, coping strategies and social support did not increase the chances of quitting. The desired result was only achieved through a combination of individual competences and social support.","Low social support shown for the empirical minimum (1), high social support for the empirical maximum (5.14). than 1.87, the association between volitional self-efficacy and continuous abstinence was significant (p<.lO). As the minimum and maximum of the mean-centred smokingspecific received social support were -2.20 and 1.94, simple slopes for individuals reporting high and low levels of smoking-specific social support were significant (at the 10% level).","[4.0, 2.0, 1.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.1505114112,Psychology_295,"While all students showed improvement in language skills necessary for reading, it was those who underwent musical training that performed the best three years later.","Taken together, these results establish that high school music classes engender gains in brain function and behavior that, although small, demonstrate the potential of enrichment to jump-start adolescent neurodevelopment.","It found that those who learned music experienced faster maturation in the brain's response to sound, and heightened sensitivity to details in sound. While all students showed improvement in language skills necessary for reading, it was those who underwent musical training that performed the best three years later. ""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" Kraus said in a press release.","Two other language tests, phonological memory and rapid naming, showed no group differences. Taken together, these results establish that high school music classes engender gains in brain function and behavior that, although small, demonstrate the potential of enrichment to jump-start adolescent neurodevelopment. The consistency of neural responses to sound tracks with language skills, suggesting that stable perceptual encoding is vital for the acquisition and maintenance of phonological categories .","[2.0, 4.0, 1.0, 4.0, 4.0]",Psychology,train,4.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1038/nn.3635,Psychology_296,"""We now have the tools to precisely map brain function both in space and time, opening up tremendous possibilities to study the human brain.""",This analysis allows identifying the cortical sources that have persistent neural activity.,"It could also shed light on processes that underlie conditions such as memory disorders or dyslexia, and could benefit patients suffering from paralysis or neurodegenerative diseases. ""This is the first time that MEG and fMRI have been connected in this way, giving us a unique perspective,"" Pantazis says. ""We now have the tools to precisely map brain function both in space and time, opening up tremendous possibilities to study the human brain.""","Relating MEG and fMRI object signals across time The above MEG-fMRI representational similarity analysis naturally extends to include the MEG time-time decoding matrices constructed earlier (Fig. This analysis allows identifying the cortical sources that have persistent neural activity. We therefore correlated the fMRI dissimilarity matrices of V1 and IT with the MEG 92 × 92 decoding matrices obtained for each pair of time points (t x ,t y ) ( Figs.","[4.0, 4.0, 3.0, 3.0, 2.0]",Psychology,train,3.2,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jalz.2018.06.2856,Psychology_297,"""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss.""","These findings, together with the lack of findings for cataract, suggest that a simplistic model of eye disease leading to poor vision leading to AD risk is not sufficiently supple to explain the overall pattern of findings.","That's a correlation that's well worth investigating further. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Eye checkups could be used to screen people with a greater risk of Alzheimer's perhaps - and while there's no cure yet, appropriate care could be provided earlier.","We performed analyses that were helpful in identifying similarities across retinal conditions and differences with a lens condition. These findings, together with the lack of findings for cataract, suggest that a simplistic model of eye disease leading to poor vision leading to AD risk is not sufficiently supple to explain the overall pattern of findings. These results suggest the likely benefit of further study to elucidate mechanisms underlying our findings.","[1.0, 3.0, 4.0, 2.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1007/s13524-014-0321-x,Psychology_298,"However, in the long run, there are no differences between the happiness levels of men and women before and after children.","A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain.","Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain. However, in the long run, there are no differences between the happiness levels of men and women before and after children. Those who have children at an older age or who are more educated have a particularly positive response to a first birth.","Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline. A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain. Among both the partnered and unpartnered, happiness increases around the birth and then decreases 11 Parents aged 17 or younger are excluded because (1) teenage childbearing is a different process than having children at young adult ages; (2) our samples include very few people who had children before turning age 18; and (3) it is difficult to construct a meaningful pre-birth baseline happiness for teen parents.","[2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_3,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""",CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.,"Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality. An important finding was that the Depressive Problems scores in this general population were correlated with functional connectivities between areas, including the lateral orbitofrontal cortex, cingulate cortex, precuneus, angular gyrus, and temporal cortex.","[4.0, 4.0, 5.0, 3.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1177/0141076814565942,Psychology_30,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.",The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) .,"The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","The HR was higher, though not significantly so, for boys circumcised at age 24 months or older (HR ¼ 1.96; 95% CI: 0.93-4.14), an estimate based on only seven cases of ASD in that group ( Table 2) . The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) . Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys.","[2.0, 4.0, 3.0, 4.0, 5.0]",Psychology,train,3.6,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1016/j.jalz.2018.06.2856,Psychology_300,"That number is expected to rise to 131.5 million by 2050, the researchers estimate.",The temporal relationship in ophthalmic conditions with AD risk is intriguing.,"""What we found was not subtle,"" said Paul Crane, a professor of medicine at the university. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" That number is expected to rise to 131.5 million by 2050, the researchers estimate.","These results suggest the likely benefit of further study to elucidate mechanisms underlying our findings. The temporal relationship in ophthalmic conditions with AD risk is intriguing. AD risk appears to be higher with recent glaucoma diagnosis, perhaps suggesting a common pathway.","[3.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.8,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1093/jcr/ucw012,Psychology_302,"Our views of ourselves can be nudged one way or the other by something as simple as an online ad.""",Future research could explore other sources for implied social labels in addition to behaviorally targeted ads.,"""We like to think we are quite certain of who we are, but this study suggests that's not quite the case,"" he said. ""We are actually open to suggestions that can change, for example, how 'outdoorsy' or 'sophisticated' we feel we are. Our views of ourselves can be nudged one way or the other by something as simple as an online ad.""","The results of our studies suggest several interesting avenues for future research. Future research could explore other sources for implied social labels in addition to behaviorally targeted ads. For example, word-of-mouth recommendations from friends and compliments from salespeople can both likely act as implied social labels (e.g., ""You can really tell a quality product when you see one"" could be interpreted as an implied label that one is particularly discerning).","[4.0, 3.0, 4.0, 3.0]",Psychology,train,3.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1080/09500693.2018.1540897,Psychology_303,"Fixing gender inequality in STEM is a big ask, but the experts behind the Report Card are hopeful that it can happen, with the right policies and intervention.",This biased view can lead to less encouragement for girls to pursue a school career in STEM and a negative social atmosphere towards girls following STEM programmes.,"The Report Card also showed that several STEM institutions had started programs like unconscious bias training to help female scientists flourish. Fixing gender inequality in STEM is a big ask, but the experts behind the Report Card are hopeful that it can happen, with the right policies and intervention. ""There are several interventions that institutions might consider to promote gender equality, including a strict and transparent policy for gender harassment; promoting a culture of respect; formal mentorship and sponsorship programming; and supportive, flexible policies for both birthing and non-birthing parents as they return to work,"" says Dr. Beeler.","Last, STEMgender stereotypes can influence teachers and study advisors to be (subconsciously or openly) prejudiced that women do not belong in the STEM world. This biased view can lead to less encouragement for girls to pursue a school career in STEM and a negative social atmosphere towards girls following STEM programmes. However, in all four meta-reviews it is concluded this is not always the case, and that even if a gender gap in STEM ability is found, this difference is too small to have such an impact that it could explain the gender differences in STEM participation .","[3.0, 2.0, 2.0, 3.0, 1.0]",Psychology,train,2.2,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1111/lcrp.12013,Psychology_304,The researchers found that closing the eyes helped the participants remember both audial and visual information.,"In other words, the benefits of eye-closure during the first free recall could not have 'carried over' to subsequent recall because there were no benefits in the first place.","Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer. The researchers found that closing the eyes helped the participants remember both audial and visual information. The researchers found that closing your eyes during an investigation is likely to make you feel less comfortable unless you have built up a good rapport with the questioner.","However, because the eyeclosure manipulation did not improve the quantity or quality of the information recalled during the first session, it did not constitute a 'good-quality' initial recall opportunity as advocated by . In other words, the benefits of eye-closure during the first free recall could not have 'carried over' to subsequent recall because there were no benefits in the first place. Hence, further research is required to investigate whether the benefits of eye-closure during initial recall can carry over to subsequent recall performance.","[4.0, 1.0, 2.0]",Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1093/jcr/ucw012,Psychology_306,"When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer.","In support of our expectation, the analyses revealed that the outdoorsy labeling index mediated the effect of targeting on purchase intentions for the solar charger (b ¼ .04, SE ¼ .02, 95% CI, .0064-.1146]) but not the hot chocolate (b ¼ À.01, SE ¼ .02, 95% CI, À.0578 to .0309).","""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said. When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer. Those are the types of labels that can change people's views about themselves.","Thus implied social labels appear to be able to lower participants' self-perceptions on a trait as long as the behavioral targeting is at least moderately accurate. In support of our expectation, the analyses revealed that the outdoorsy labeling index mediated the effect of targeting on purchase intentions for the solar charger (b ¼ .04, SE ¼ .02, 95% CI, .0064-.1146]) but not the hot chocolate (b ¼ À.01, SE ¼ .02, 95% CI, À.0578 to .0309). In the condition in which the hot chocolate was positioned as appropriate for the outdoors, we expected significant mediation only at moderate and high levels of a priori interest in outdoors products (i.e., when targeting was at least moderately accurate).","[1.0, 4.0, 1.0, 2.0]",Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1080/14635240.2015.1029641,Psychology_307,"Simply put, we think better on our feet than in our seat.""","The treatment group exhibited greater levels of academic engagement than the control group in the fall, with a statistically significant difference of the average total engagement score of 4.21 ( p ¼ 0.003) noted.","Benden says he wasn't surprised at the results of the study, given that previous research has shown that physical activity, even at low levels, may have beneficial effects on cognitive ability. Simply put, we think better on our feet than in our seat."" The key lesson to take from this research, Benden says, is that school districts that put standing desks in classrooms may be able to address two problems at the same time: academic performance and childhood obesity.","The mean and standard error plots for the total engaged time (avgTotEng), for different treatment groups at fall and spring are shown in Figure 1 . The treatment group exhibited greater levels of academic engagement than the control group in the fall, with a statistically significant difference of the average total engagement score of 4.21 ( p ¼ 0.003) noted. In the spring semester, the control group showed a greater increase in academic engagement relative to the treatment group.","[1.0, 3.0, 2.0, 1.0]",Psychology,train,1.75,news,http://www.futurity.org/standing-desks-child-attention-905882/
10.1016/j.jarmac.2014.03.005,Psychology_308,"The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created.","In short, there is clear meta-analytic evidence that post-warnings lead to a real improvement of memory performance for original details that have been the target of misinformation, whereas the evidence for associated costs to control memory performance is more tenuous.","""High cognitive ability may allow individuals to overcome the biasing effect of political orientation and more effectively monitor the sources of their memories,"" the authors note. The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created. Devising strategies to prevent false voter memories may require implementing more sophisticated measures, perhaps in addition to issuing warnings about misinformation.","By comparison, the 1.21 control costs odds ratio is much lower and does not differ significantly from the no-effect value of 1. In short, there is clear meta-analytic evidence that post-warnings lead to a real improvement of memory performance for original details that have been the target of misinformation, whereas the evidence for associated costs to control memory performance is more tenuous. Across 25 direct comparisons (stemming from 10 papers), misled and control Misinformation Endorsement in the no-warning condition was 42.3% and 17.7%, respectively.","[5.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1016/j.jpeds.2017.10.028,Psychology_31,The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.,"There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[2.0, 2.0, 2.0, 1.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1016/j.jpeds.2017.10.028,Psychology_310,"Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence.","The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed. That held true even after the researchers took into account the person's age, gender, parents' education and any history of child physical abuse.","Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence. Furthermore, variables known to relate to dating violence were controlled for, which highlights the importance of the unique impact of corporal punishment on perpetration of dating violence and addresses longstanding criticisms regarding a potentially confounding link between corporal punishment and poor outcomes.","[2.0, 1.0, 1.0]",Psychology,train,1.3333333333333333,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1001/jamapsychiatry.2018.3514,Psychology_312,"""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognizing a psychosis subtype of suicide,"" he continued.","We found that co-occurring psychopathology is only a partial mediator of the association between PEs and suicidal behavior; that is, PEs are a marker of risk for later suicidal behavior in excess of the risk associated with co-occurring mental disorders.","""Given that about 1 million people die by suicide every year, that's a very encouraging prospect for suicide prevention."" ""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognizing a psychosis subtype of suicide,"" he continued. ""If we are to understand suicide, we need to understand a lot more about perceptual abnormalities,"" added doctoral student and co-author Kathryn Yates of RCSI Psychiatry.","For one, PEs are associated with increased odds of suicidal behavior even in individuals without a mental disorder. We found that co-occurring psychopathology is only a partial mediator of the association between PEs and suicidal behavior; that is, PEs are a marker of risk for later suicidal behavior in excess of the risk associated with co-occurring mental disorders. (Figure 2 includes examples of mediating variables in the association between PEs and suicidal ideation and behavior.)","[5.0, 4.0, 3.0, 4.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=38199144066&p=1pl&v=1&x=PR70GSjRLk3dzNiHIohVjQ
10.1093/chemse/bjt066,Psychology_313,The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels.,Participants indicated that there was an odor when in fact there wasn't in 26% of the cases when evaluating intensity.,"The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels. Conversely, the same odours were considered unpleasant and inedible when associated with negative labels - even the food odours.","When presented with the positive label, geraniol (Md = 6.42) was perceived as more intense than when presented with the negative label (Md = 5.42). Participants indicated that there was an odor when in fact there wasn't in 26% of the cases when evaluating intensity. Wilcoxon signed-rank tests analysis of the ""false alarm"" trials (z = 4.37, P < 0.001, corrected, with a large effect size [r = 0.53]) revealed that intensity ratings were significantly higher for ""correct detection"" trials (Md = 6.92) than for ""false alarm"" trials (Md = 2.25).","[1.0, 2.0, 1.0, 1.0]",Psychology,train,1.25,news,http://www.healthcanal.com/eyes-vision/47601-smelling-with-our-eyes-descriptions-affect-odour-perception.html
10.1016/j.nicl.2015.02.009,Psychology_314,Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task.,"Instead, the data support the view that hippocampal overactivity contributes to symptomatic impairment in the MCI phase of disease (for review see Ewers et al., 2011) .","""At the same time, it improves memory performance on a task that depends on the hippocampus."" Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task. The ideal dosing found in this clinical study matched earlier preclinical studies in animal models.","Importantly, no evidence was found in this study to support a beneficial compensatory role in cognition for excess hippocampal activation. Instead, the data support the view that hippocampal overactivity contributes to symptomatic impairment in the MCI phase of disease (for review see Ewers et al., 2011) . The deleterious effect of hippocampal overactivity detected by fMRI is further supported by recent evidence of a distinctive gene expression profile underlying excessive hippocampal excitability in MCI patients.","[1.0, 2.0, 2.0, 2.0, 1.0]",Psychology,train,1.6,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1111/cdev.12250,Psychology_316,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time .","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","With respect to alcohol and marijuana use, early adolescent pseudomature behavior was actually a better predictor of future such substance use problems in adulthood than were even early adolescent levels of such use. In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time . This finding indicates just how potentially important this social pathway toward future difficulties may be in identifying individuals at risk for long-term problems with alcohol and substance use.","[2.0, 4.0, 4.0, 2.0, 3.0]",Psychology,train,3.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1001/jamapsychiatry.2018.1941,Psychology_317,"The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep.","We note that only 2 of the 123 items in the Adult Self Report questionnaire, which are used to calculate the Depressive Problems Score, are on the topic of sleep quality, and so these are unlikely to account for the correlations in this study.","The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep. This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).","The correlation was highly significant (r = 0.371; P < .001; Figure 1B ). We note that only 2 of the 123 items in the Adult Self Report questionnaire, which are used to calculate the Depressive Problems Score, are on the topic of sleep quality, and so these are unlikely to account for the correlations in this study. Although participants of the HCP data set were not selected to have a psychiatric disorder and most are healthy control participants, the Depressive Problems raw score was a useful indicator of depression, in that 92 participants who reported having been diagnosed with a major depressive episode also had significantly higher scores on this measure.","[2.0, 1.0, 1.0, 3.0, 1.0]",Psychology,train,1.6,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1001/jamapsychiatry.2018.3514,Psychology_318,"""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognising a psychosis subtype of suicide,"" added Dr Kelleher.",The authors went on to directly compare diagnostic groups with vs without PEs and found that patients with depression and PEs had a 9-fold increased odds of suicide attempt compared with patients with depression who did not have PEs.,"Given that about 1 million people die by suicide every year, that's a very encouraging prospect for suicide prevention."" ""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognising a psychosis subtype of suicide,"" added Dr Kelleher. There are still a lot of unanswered questions; but this research points to new avenues to improve prediction of suicidal behaviour.""","23 This study found that PEs were not associated with a significantly increased odds of isolated suicidal ideation (that is, suicidal ideation in the absence of a suicide plan or suicide attempt), but that PEs were associated with a 3-fold increased odds of suicide attempt. The authors went on to directly compare diagnostic groups with vs without PEs and found that patients with depression and PEs had a 9-fold increased odds of suicide attempt compared with patients with depression who did not have PEs. Patients with an anxiety disorder and PEs had a 15-fold increased odds of suicide attempt compared with patients with an anxiety disorder who did have PEs.","[3.0, 2.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=37828547572&p=1pl&v=1&x=0DCeKj2mrndVr_6QSdn9XA
10.1007/s13524-014-0321-x,Psychology_319,"Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.",Unpartnered British experience smaller increases in happiness around the birth and do not experience long-run increases in happiness post-birth.,"The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.","In Britain, partnered parents have larger increases in happiness in the year the child is born and have upward happiness trajectories as their children mature. Unpartnered British experience smaller increases in happiness around the birth and do not experience long-run increases in happiness post-birth. The differences are not significant (p > .05) for any single time point but are significant The model includes as control variables age and period dummy variables, and fixed effects for individuals.","[1.0, 2.0, 2.0, 1.0]",Psychology,train,1.5,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1505114112,Psychology_32,"(EaglebrookSchool/CC BY 2.0)

Band Class Helps Teens Learn How to Learn

Music training, introduced as late as high school, may help improve how a teenager's brain responds to sound and could sharpen their hearing and language skills, too.","However, JROTC training likely leads to a separate set of benefits outside the auditory domain.","""Although learning to play music does not teach skills that seem directly relevant to most careers,"" says Nina Kraus, ""music may engender what educators refer to as 'learning to learn.'"" (EaglebrookSchool/CC BY 2.0)

Band Class Helps Teens Learn How to Learn

Music training, introduced as late as high school, may help improve how a teenager's brain responds to sound and could sharpen their hearing and language skills, too. The findings suggest that music instruction helps enhance skills that are critical for academic success.","Although JROTC training requires discipline and time investment, it does not mandate fine auditory perceptual judgments, which may explain why we do not find auditory system enhancements in the JROTC group. However, JROTC training likely leads to a separate set of benefits outside the auditory domain. One possibility, for example, is that the mental discipline acquired and practiced over the course of JROTC training strengthens attentional control.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.theepochtimes.com/n3/1677179-band-class-helps-teens-learn-how-learn/
10.1016/j.jalz.2018.06.2856,Psychology_322,"Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said.","Recent and established AMD and DR were associated with allcause dementia, and risks for DR were much larger (Supplementary Table 1 ).","""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss,"" Lee explained in a university news release. Patients with age-related macular degeneration, diabetic retinopathy or glaucoma had a 40 to 50 percent greater risk of Alzheimer's disease than those without the eye conditions, the researchers said. ""What we found was not subtle,"" said Paul Crane, a professor of medicine at the university.","Restricting to probable AD (n 5 522) resulted in similar estimates for recent ( For all-cause dementia, glaucoma risks were attenuated though still non-null for recent diagnosis. Recent and established AMD and DR were associated with allcause dementia, and risks for DR were much larger (Supplementary Table 1 ). Models with non-AD dementia that treated AD as a competing risk confirmed the expected strong relationship between DR and non-AD dementia (Supplementary Table 1 ).","[3.0, 5.0, 1.0, 4.0, 3.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34792864437&p=1pl&v=1&x=POVsoSxsrI9yWH7psyoAxQ
10.1007/s13524-014-0321-x,Psychology_323,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births.","Our modeling approach, which follows with some modifications, 5 allows observing anticipation, shortterm (1 to 4 years) changes, and long-term (5 to 18 years) changes in happiness over the transition to parenthood while controlling for time-invariant unobserved characteristics, such as personality or genetic endowments.","The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births. The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.","We assume the cardinality of life satisfaction because treating life satisfaction as ordinal versus cardinal makes little difference . Our modeling approach, which follows with some modifications, 5 allows observing anticipation, shortterm (1 to 4 years) changes, and long-term (5 to 18 years) changes in happiness over the transition to parenthood while controlling for time-invariant unobserved characteristics, such as personality or genetic endowments. 3) , education (Fig.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1505114112,Psychology_324,"But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life.",The maintenance of response consistency in the music training group may prolong sensitivity to auditory learning.,"The findings have important implications for teens in low-income neighborhoods, as their language development is often below that of their wealthier counterparts. But perhaps the best benefit to musical training, Kraus found, was that the developmental outcomes strengthened the brain well enough to stall cognitive decline later in life. Source: Tierney A, Krizman J, Kraus N. Music training alters the course of adolescent auditory development.","Thus, music training may maintain heightened synaptic density within the auditory system to enable the learning and performance of challenging auditory tasks, much as songbirds show seasonal increases in synaptogenesis that coincide with the onset of the preferential period for learning new songs . The maintenance of response consistency in the music training group may prolong sensitivity to auditory learning. Future work could test this hypothesis by measuring auditory learning in adolescents with or without prior musical experience.","[2.0, 3.0, 1.0, 2.0, 2.0]",Psychology,train,2.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1038/s41598-017-03627-7,Psychology_325,"From fire-walking rituals and tear-jerker movies to choirs singing, and yes, the ultimate, googly-eyed love stares that make romantic couples, well, even more googly, researchers found evidence that women with highly empathetic partners reported increased pain reduction.","As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect.","In grownups, this interpersonal touch can help regulate responses to stress, increasing trust and emotional well-being. From fire-walking rituals and tear-jerker movies to choirs singing, and yes, the ultimate, googly-eyed love stares that make romantic couples, well, even more googly, researchers found evidence that women with highly empathetic partners reported increased pain reduction. This study is in line with earlier research which suggests communicating numerous emotions with touch, including decoding anger, fear, love and gratitude.","Physiologically, interpersonal touch increases the coupling of electrodermal activity and pulse rate variability 35 and modulates blood pressure reactivity to stress 36 as well as reactivity to distress 37 . As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect. In addition, during the pain-alone condition, the women's pain ratings were marginally higher than in the partner-no touch condition (M diff = 0.29, p = 0.093).","[3.0, 2.0, 4.0, 2.0, 3.0]",Psychology,train,2.8,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1111/cdev.12250,Psychology_327,Allen and his team found evidence to suggest that this behavior might actually hurt social status in school.,One potential explanation for these findings is provided by cumulative continuity theory .,"The reason these ""cool"" kids are lost at sea as adults isn't karma working its magic -- it's more scientific than that. Allen and his team found evidence to suggest that this behavior might actually hurt social status in school. When it ended, they were 23.","In terms of competence with peers, pseudomature behavior in early adolescence predicted not only declining popularity with peers across adolescence but also lower levels of peer competence, as rated by peers, in early adulthood. One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","[1.0, 4.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1001/jamapsychiatry.2018.3514,Psychology_328,"There are still a lot of unanswered questions, but this research points to new avenues to improve prediction of suicidal behavior.""","Using a convergent functional genomics approach, Niculescu et al [54] [55] [56] showed that many of the top biomarkers for suicide are also biomarkers for psychotic disorders and high hallucination states.","""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognizing a psychosis subtype of suicide,"" he continued. ""If we are to understand suicide, we need to understand a lot more about perceptual abnormalities,"" added doctoral student and co-author Kathryn Yates of RCSI Psychiatry. There are still a lot of unanswered questions, but this research points to new avenues to improve prediction of suicidal behavior.""","In the context of high stress and poorer communication skills, this might adversely affect the individual's ability to formulate logical plans to manage perceived challenges and instead increase the likelihood of turning to suicide. Using a convergent functional genomics approach, Niculescu et al [54] [55] [56] showed that many of the top biomarkers for suicide are also biomarkers for psychotic disorders and high hallucination states. A notable strength of the review is that we used longitudinal studies, which established a temporal association between PEs and suicidal behavior.","[1.0, 2.0, 4.0, 4.0, 5.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38199144066&p=1pl&v=1&x=PR70GSjRLk3dzNiHIohVjQ
10.1007/s13524-014-0321-x,Psychology_33,"Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline.","Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below. Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline. A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain.","[3.0, 2.0, 2.0, 2.0, 1.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Psychology_331,"A first-born child brought the most happiness, no matter what age the parents were.",Unpartnered British experience smaller increases in happiness around the birth and do not experience long-run increases in happiness post-birth.,"Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness. A first-born child brought the most happiness, no matter what age the parents were. There was a 50 percent decrease in happiness during the birth of a second child, followed by a total slump by the time the third child is born.","In Britain, partnered parents have larger increases in happiness in the year the child is born and have upward happiness trajectories as their children mature. Unpartnered British experience smaller increases in happiness around the birth and do not experience long-run increases in happiness post-birth. The differences are not significant (p > .05) for any single time point but are significant The model includes as control variables age and period dummy variables, and fixed effects for individuals.","[2.0, 1.0, 3.0, 2.0, 1.0]",Psychology,train,1.8,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1001/jamapsychiatry.2018.1941,Psychology_334,"From the other side, people with insomnia also have a higher risk of depression and anxiety.","The amygdala is not included as a separate area in the Shen atlas, but does have FC related to sleep quality as shown here.","""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" From the other side, people with insomnia also have a higher risk of depression and anxiety. While this particular study found strong neural connections in the association of depressive problems with poor sleep quality, rather than the other way around, in general the effects can work both ways.","All of the links are positively correlated with the sleep quality index (PSQI). The amygdala is not included as a separate area in the Shen atlas, but does have FC related to sleep quality as shown here. A link positively correlated with the Depressive Problems score indicates that the functional connectivity of that link is positively correlated with the Depressive Problems score.","[1.0, 3.0, 1.0, 1.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1093/chemse/bjt066,Psychology_335,"This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process.","Furthermore, the participants were also more liberal in their decision making as indicated by the criterion c (c = −0.53), suggesting that when they are in doubt as to whether an odor was present or not, they would rather state that there was an odor instead of stating that there wasn't one.","""Moreover, this is the first time we have been able to influence the edibility perception of an odour, even though the positive and negative labels accompanying the odours showed non-food words,"" adds Frasnelli. This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process. However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive.","This suggests that all the participants can discriminate very well between the odor condition and the no-odor condition. Furthermore, the participants were also more liberal in their decision making as indicated by the criterion c (c = −0.53), suggesting that when they are in doubt as to whether an odor was present or not, they would rather state that there was an odor instead of stating that there wasn't one. The overall average ratings were 2.80 (SD = 0.95, range 1.30-6.67) for edibility, 4.11 (SD = 0.94, range 1.57-5.82) for pleasantness, and 6.54 (SD = 1.23, range 2.60-8.67) for intensity.","[3.0, 3.0, 1.0, 3.0]",Psychology,train,2.5,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jalz.2018.06.2856,Psychology_336,"""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye.""","Discussion: Increased AD risk was found for recent glaucoma diagnoses, established AMD diagnoses, and both recent and established DR. People with certain ophthalmic conditions may have increased AD risk.","""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" The possible connections need more study.","The recent and established hazard ratio were 1.46 (P 5 .01) and 0.87 (P 5 .19) for glaucoma, 1.20 (P 5 .12) and 1.50 (P , .001) for AMD, and 1.50 (P 5 .045) and 1.50 (P 5 .03) for DR. Discussion: Increased AD risk was found for recent glaucoma diagnoses, established AMD diagnoses, and both recent and established DR. People with certain ophthalmic conditions may have increased AD risk. Research regarding AD risk factors may lead to early detection and preventive measures based on better understanding neurodegenerative processes .","[1.0, 1.0, 4.0, 2.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1093/jcr/ucw012,Psychology_338,"For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad.",Thus changes in self-perception as a result of behavioral targeting only occur when targeting is at least moderately accurate.,"If an ad makes you feel sophisticated or environmentally conscious, you are more likely to engage in all kinds of behaviors related to that trait - not just buy the advertised product,"" Reczek said. For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.","The lack of significance at the top of the scale (i.e., 10 of 10 choices) likely reflects either a ceiling effect (due to the fact that participants who made 10 outdoors-related choices already perceive themselves as so outdoorsy that there is no room for movement as a result of an implied social label) or a lack of power (as only seven people made 10 outdoors-related choices: M behavioral ¼ 6.80, M nontargeted ¼ 7.00; F(1, 5) ¼ .36, p ¼ .58). Thus changes in self-perception as a result of behavioral targeting only occur when targeting is at least moderately accurate. The same regression model within the indoors positioning condition revealed that participants viewed themselves as less outdoorsy when the ad was identified as behaviorally targeted (b ¼ À.27, t(134) ¼ À2.16, p < .05, g 2 ¼ .01) and when they had made fewer outdoors-related prior choices (b ¼ .47, t(134) ¼ 8.03, p < .0001, g 2 ¼ .33).","[4.0, 3.0, 2.0, 3.0]",Psychology,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1186/s13229-018-0246-0,Psychology_34,"""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","First, results from Jilin City where both mainstream and special school data were available revealed a similar prevalence of autism in China to the West, at around 1% .","In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China. We have been able to use a standardized screening methodology, allowing us to compare the results with Western countries to show that autism occurs broadly at the same rate, irrespective of culture.""","There are four key findings from this study. First, results from Jilin City where both mainstream and special school data were available revealed a similar prevalence of autism in China to the West, at around 1% . Second, in Shenzhen and Jiamusi cities, where only mainstream data were available, prevalence is also in line with Western estimates .","[5.0, 2.0, 2.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1093/jcr/ucw012,Psychology_340,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","Specifically, we found that labels that are unconnected to prior behavior (i.e., inconsistent with consumers' a priori interest in trait-related products) do not prompt adjustments to self-perceptions and affect behavior; low levels of accuracy yield no effect, whereas moderate to high levels of accuracy produce social labeling effects.","""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","The results of study 4 demonstrate that the accuracy of a behaviorally targeted ad moderates the direct effect on self-perceptions and the mediated effect on behavior through self-perceptions. Specifically, we found that labels that are unconnected to prior behavior (i.e., inconsistent with consumers' a priori interest in trait-related products) do not prompt adjustments to self-perceptions and affect behavior; low levels of accuracy yield no effect, whereas moderate to high levels of accuracy produce social labeling effects. The results further indicate that while consumers recognize even inaccurate behaviorally targeted ads as implied social labels, it is accuracy (i.e., the match between this prior behavior and the implied label) that determines whether this label is perceived to be relevant to the self, leading to adjustments in self-perceptions that play a mediating role in subsequent trait-related behavior.","[2.0, 3.0, 1.0, 2.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdep.12038,Psychology_341,"""Also, corporal punishment wasn't being used as a last resort.",Spanking alone does not teach children why their behavior was wrong or what they should do instead .,"The children in the study who were hit or slapped by their parents typically misbehaved again within 10 minutes. ""Also, corporal punishment wasn't being used as a last resort. On average, parents hit or spanked just half a minute after the conflict began.""","It is difficult to imagine that a parent would be able to meet all these criteria when administering spanking; indeed, it would likely be both inadvisable and bordering on abusive if parents spanked children following every instance of a given misbehavior. Spanking alone does not teach children why their behavior was wrong or what they should do instead . Rather, it teaches them that they must behave when the threat of physical punishment exists, but once the threat is gone, they have no reason to behave appropriately .","[2.0, 3.0, 2.0, 3.0, 2.0]",Psychology,train,2.4,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1038/s41598-018-30980-y,Psychology_342,"Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report.",These results support that the relationship between memory performance change across both the nap and overnight sleep bouts was fully mediated by nap SWA (Fig.,"To do this, they presented children ages approximately three to five years (34-64 months) with faces paired with mean or nice word descriptions, but they saw no significant main effects of emotional valence on recognition memory. Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","When nap SWA was controlled for, the standardized regression coefficient for the relationship between ΔRecall nap and ΔRecall overnight was reduced from B = −0.488, (p = 0.029) to B = −0.364 (p = 0.182). These results support that the relationship between memory performance change across both the nap and overnight sleep bouts was fully mediated by nap SWA (Fig. 4) .","[5.0, 5.0, 3.0, 2.0, 2.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_346,"""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","However, when the question is how children influence parental well-being, it is important to analyze individual changes over time instead of only comparing parents with the childless.","""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings. Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources.","These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing. However, when the question is how children influence parental well-being, it is important to analyze individual changes over time instead of only comparing parents with the childless. Otherwise, the analyses may be biased by genetic factors, personality, or other unobserved or difficult-to-measure fixed characteristics, such as orientation toward career versus family, which may be associated with both fertility behavior and subjective wellbeing .","[4.0, 1.0, 2.0, 4.0, 2.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Psychology_347,Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility.,"Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution.","Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources. Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.","If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced. Moreover, higher-parity births might increase happiness less than the first birth because of resource dilution. However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births.","[3.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1186/s13229-018-0246-0,Psychology_35,"""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.",The prevalence estimate indicates that the prevalence of autism in China is similar to estimates in Western countries.,"In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China. We have been able to use a standardized screening methodology, allowing us to compare the results with Western countries to show that autism occurs broadly at the same rate, irrespective of culture.""","The prevalence in those two schools was 119 per 10,000 . The prevalence estimate indicates that the prevalence of autism in China is similar to estimates in Western countries. These children urgently need support to understand the difficulties and challenges they might face in the future to prepare themselves for school and the workplace.","[4.0, 5.0, 4.0, 5.0, 2.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1111/cdev.12250,Psychology_350,"Allen says he believes that part of the problem may be that as popular youth grow older, they have to do increasingly extreme things in order to grab the attention of their peers and keep it.","The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers.","Unfortunately, even when examining certain external factors related to geographic region, family income or gender of the participants, the results remained about the same. Allen says he believes that part of the problem may be that as popular youth grow older, they have to do increasingly extreme things in order to grab the attention of their peers and keep it. Of course, the vanity of focusing on social hierarchies never fares too well in the end.","Third, ""popularity"" is now recognized as potentially referring to both preference-based measures (i.e., who do teens prefer as associates) and statusbased measures (i.e., who do teens perceive as being ""popular""). The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers. It remains possible, for example, that teens engaging in pseudomature behavior might possibly maintain a degree of status-based popularity (i.e., perceptions by others that they are members of the ""popular"" group) even if preference-based measures (such as used in this study, indicating other teens' actual desire to spend time with study participants) show declining social preference over time for teens engaging in pseudomature behavior.","[3.0, 2.0, 1.0, 3.0, 3.0]",Psychology,train,2.4,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1111/cdev.12250,Psychology_353,"Allen says he believes that part of the problem may be that as popular youth grow older, they have to do increasingly extreme things in order to grab the attention of their peers and keep it.","Even almost a decade later, however, social status concerns continued to play a key role in the lives of these individuals as adults, as they found themselves more likely to perceive that their romantic partners were ending relationships with them based upon their own lack of social status.","Unfortunately, even when examining certain external factors related to geographic region, family income or gender of the participants, the results remained about the same. Allen says he believes that part of the problem may be that as popular youth grow older, they have to do increasingly extreme things in order to grab the attention of their peers and keep it. Of course, the vanity of focusing on social hierarchies never fares too well in the end.","Indeed, it is possible that this fading popularity advantage may be what leads these adolescents to pursue more and more extreme behaviors in an effort to attain status with at least a subset of their peers, although this explanation remains for future research to examine. Even almost a decade later, however, social status concerns continued to play a key role in the lives of these individuals as adults, as they found themselves more likely to perceive that their romantic partners were ending relationships with them based upon their own lack of social status. One explanation for this long-term link is that teens who engage in high levels of pseudomature behavior have set themselves on a path in which they place an outsized role on the importance of social status in relationships.","[4.0, 4.0, 4.0, 2.0]",Psychology,train,3.5,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1093/jcr/ucw012,Psychology_354,"Our views of ourselves can be nudged one way or the other by something as simple as an online ad.""",We also contribute to the broader literature on self-learning ) by demonstrating that implied social labels such as those from behaviorally targeted ads can be a source of self-learning and that such learning is contingent on the connection between this implied information and a person's prior behavior.,"""We like to think we are quite certain of who we are, but this study suggests that's not quite the case,"" he said. ""We are actually open to suggestions that can change, for example, how 'outdoorsy' or 'sophisticated' we feel we are. Our views of ourselves can be nudged one way or the other by something as simple as an online ad.""","In doing so, we contribute to the literature by demonstrating that labels do not have to reference the consumer to have an effect (as has been shown in past research), but that consumers can be affected by implied labels supplied by external sources. We also contribute to the broader literature on self-learning ) by demonstrating that implied social labels such as those from behaviorally targeted ads can be a source of self-learning and that such learning is contingent on the connection between this implied information and a person's prior behavior. This research also adds to the literature on identity marketing.","[4.0, 4.0, 4.0, 2.0, 4.0]",Psychology,train,3.6,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1016/j.jalz.2018.06.2856,Psychology_356,The possible connections need more study.,Future directions: Caregivers and health-care workers should facilitate adequate ophthalmic care for older individuals at risk of dementia.,"""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" The possible connections need more study. She said a better understanding of neurodegeneration in the eye and the brain could bring more success in diagnosing Alzheimer's early and developing better treatments.",3. Future directions: Caregivers and health-care workers should facilitate adequate ophthalmic care for older individuals at risk of dementia. Eye care providers should be aware of increased AD risk in certain ophthalmic conditions.,"[4.0, 2.0, 1.0, 1.0, 5.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1111/lcrp.12013,Psychology_357,"The team found that when the participants closed their eyes, they were able to remember 23 percent more information than the people in the other groups.","We suspect that the format of the initial recall task determines whether the memory is 'locked' in place (e.g., Burke et al.","Close

If you're cramming for a test or have an important date to remember, you might find this simple tip useful: close your eyes. The team found that when the participants closed their eyes, they were able to remember 23 percent more information than the people in the other groups. Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer.","Unlike , we did not find that the initial free-recall attempt 'locked' the memory in place; both the amount and the accuracy of reported information decreased from the first to the second session. We suspect that the format of the initial recall task determines whether the memory is 'locked' in place (e.g., Burke et al. used a recognition test rather than a free-recall task), which could be investigated in future research.","[2.0, 2.0, 2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1111/cdep.12038,Psychology_358,King also noted that corporal punishment is disproportionately applied to students.,We now have enough research to conclude that spanking is ineffective at best and harmful to children at worst.,"""Policymakers must eradicate violence against schoolchildren and instead foster learning environments that are safe and productive."" King also noted that corporal punishment is disproportionately applied to students. Boys =, children of color and kids with disabilities are more likely to be physically punished.","Human rights-based arguments have little influence in the United States until we ratify the Convention on the Rights of the Child; the United States is one of only three countries not to have done so (the others are Somalia and South Sudan, the latter of which gained independence in 2011). We now have enough research to conclude that spanking is ineffective at best and harmful to children at worst. We thus have research-based and humanrights-based reasons for not spanking our children.","[1.0, 2.0, 2.0, 2.0, 1.0]",Psychology,train,1.6,news,http://www.universityherald.com/articles/51514/20161124/education-secretary-schools-stop-use-corporal-punishment.htm
10.1007/s13524-014-0321-x,Psychology_359,The researchers also discovered that having a baby at older age is more beneficial psychologically.,"Second, if we observe the transition to parenthood being accompanied by negative rather than positive changes in well-being, this can lead to lower fertility intentions, lower realized fertility, and also postponement if one surmises that less time is needed to have a smaller optimal number of children.","Sociologists Mikko Myrskyla and Rachel Margolis found out that third child does not make subjective well-being greater. The researchers also discovered that having a baby at older age is more beneficial psychologically. Although many different explanations of this phenomenon were proposed, relatively little attention was paid to subjective well-being of parents.","First, if we observe that young parents have negative well-being trajectories but that older parents with more resources have easier transitions to parenthood, this may influence postponement of a first birth through social learning. Second, if we observe the transition to parenthood being accompanied by negative rather than positive changes in well-being, this can lead to lower fertility intentions, lower realized fertility, and also postponement if one surmises that less time is needed to have a smaller optimal number of children. Thus, one's own experiences may influence further parity progression after a first birth, and social learning from other people's subjective experiences may influence decisions 1 Part of the gap between desired and actual fertility is explained by measurement: desired fertility is a cohort concept, but fertility behavior is often measured on a period basis.","[2.0, 1.0, 2.0]",Psychology,train,1.6666666666666667,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1177/0141076814565942,Psychology_36,"The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed.","During follow-up through April 2013, a total of 5033 boys (1.5%) and 1026 girls (0.3%) were diagnosed with ASD before their 10th","The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","having the same mother and father) of a boy undergoing ritual circumcision was the time-dependent exposure variable shifting from unexposed to exposed on the (first) date of ritual circumcision in a brother (for sisters born before the brother's ritual circumcision) or at birth (for sisters born later). During follow-up through April 2013, a total of 5033 boys (1.5%) and 1026 girls (0.3%) were diagnosed with ASD before their 10th Several examined birth and perinatal characteristics exhibited non-trivial associations with ASD risk, and all, except twin status, had associated Wald test p values < 0.05 in univariate analyses among boys (Table 1) .","[2.0, 3.0, 4.0, 4.0, 2.0]",Psychology,train,3.0,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1016/j.jpeds.2017.10.028,Psychology_360,But continuing violent disciplinary fear tactics instead of teaching is frankly abuse apologist and triggering to abuse survivors.,"Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","You may have turned out ""fine"". But continuing violent disciplinary fear tactics instead of teaching is frankly abuse apologist and triggering to abuse survivors. -- 100% tenidite quevtefani (@scarlettroseV) January 6, 2018

She is ABSOLUTELY right!!","Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","[1.0, 1.0, 3.0, 1.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=33001285672&p=1pl&v=1&x=mY8JhuBWW01QmuVJVuzYBw
10.1016/j.jpeds.2017.10.028,Psychology_361,"Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.",Several important findings of our study merit discussion.,"The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed. That held true even after the researchers took into account the person's age, gender, parents' education and any history of child physical abuse.","Notably, sex and parent education Several important findings of our study merit discussion. First, more than one-half (68%) of participants in this sample reported experiencing corporal punishment as children.","[1.0, 1.0, 1.0, 2.0]",Psychology,train,1.25,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1038/s41598-017-03627-7,Psychology_362,"This study is in line with earlier research which suggests communicating numerous emotions with touch, including decoding anger, fear, love and gratitude.","In line with our hypothesis, the male partner's empathic accuracy significantly moderated the effect of touch on synchronization for respiration fluctuations (F (4,28000) = 27.87, p < 0.0001, ΔBIC = 419439.8, ΔR 2 = 0.23).","From fire-walking rituals and tear-jerker movies to choirs singing, and yes, the ultimate, googly-eyed love stares that make romantic couples, well, even more googly, researchers found evidence that women with highly empathetic partners reported increased pain reduction. This study is in line with earlier research which suggests communicating numerous emotions with touch, including decoding anger, fear, love and gratitude. However, this current study acknowledges that mechanisms identified as social touch analgesia (pain-relief without loss of consciousness), remains widely unknown.","Empathic accuracy and trait empathy measurements demonstrated high correlation (r = 0.62, p < 0.001). In line with our hypothesis, the male partner's empathic accuracy significantly moderated the effect of touch on synchronization for respiration fluctuations (F (4,28000) = 27.87, p < 0.0001, ΔBIC = 419439.8, ΔR 2 = 0.23). More specifically, a high level of empathic accuracy (one standard deviation above the mean) compared to a low level (one standard deviation below the mean) was associated with increased coupling between female velocity and male acceleration in respiration during the touch condition (Δζ t(p) = 0.028, p < 0.001, 95% CI [0.016, 0.040]).","[2.0, 2.0, 1.0]",Psychology,train,1.6666666666666667,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1111/cdev.12250,Psychology_363,"By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement.","The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers.","Meanwhile, as the young James Deans and Miley Cyruses aged they had to engage in ever-riskier behavior to keep thinking of themselves as cool. By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement. Turns out being a cool kid has a really short shelf life.","Early reliance upon minor acts of delinquency to impress peers may thus lead to a greater likelihood of associating with deviance-prone peers, who in turn would only be impressed by more and more serious acts of deviance over time. The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers. Similarly, whereas minor levels of alcohol or substance use may impress a subgroup of peers in early adolescence, by early adulthood, such behavior would gain little notice, and it may take heavy drinking and more serious substance use to try to impress adult peers.","[2.0, 3.0, 1.0, 2.0]",Psychology,train,2.0,news,http://www.scientificamerican.com/podcast/episode/cool-kids-age-poorly/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29
10.1016/j.jalz.2018.06.2856,Psychology_364,"Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions.",Our specific findings also mitigate the possibility that they merely reflect age-related phenomena.,"""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions. Cataract diagnosis was not an Alzheimer's disease risk factor.","Several factors suggest the effects we found are specific to these ophthalmic conditions and not merely agerelated phenomena. Our specific findings also mitigate the possibility that they merely reflect age-related phenomena. We included separate terms for recent vs. established condition, and the pattern of findings was not consistent across conditions.","[3.0, 1.0, 1.0]",Psychology,train,1.6666666666666667,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1007/s13524-014-0321-x,Psychology_366,"In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status.",A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth .,"The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby. In addition, the data reveals that a reaction to a birth is highly influenced by such sociodemographic characteristics as age or socioeconomic status. ""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim.","These might explain why women anticipate a first birth more than men, with stronger happiness increases prior to and around the birth and a larger drop afterward. A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth . Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms.","[1.0, 2.0, 1.0, 2.0, 2.0]",Psychology,train,1.6,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1001/jamapsychiatry.2013.4081,Psychology_367,Results for older parents were varied as well.,"Within this group, we found no prominent association between parental age and the risk for bipolar disorder.","This could be due to the socioeconomic stress of being raised by unprepared teens, the authors suggest. Results for older parents were varied as well. While older women posed increased risk only for mental retardation (which may, the authors say, reflect the well-known association between maternal age and Down syndrome), children with fathers over the age of 45 had a 34% increased risk for psychiatric illnesses overall, and showed a clear trend of steadily increasing risk over the age of 29.","For the general category of mood disorders, the offspring of teenaged mothers or fathers and the offspring of older fathers had small but significantly increased risks (compared with the reference category). Within this group, we found no prominent association between parental age and the risk for bipolar disorder. The risk for schizophrenia and related disorders was associated with older fathers (≥45 years vs the reference category; IRR, For the broad group of neurotic and stress-related disorders (ICD-10-DRC codes F40-F48), the offspring of teenaged mothers were at the highest risk (IRR, 1.49 [95% CI, 1.45-","[1.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://qz.com/170543/men-shouldnt-wait-too-long-to-have-kids-either/
10.1007/s13524-014-0321-x,Psychology_368,"""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.","At first interview, parents' levels of life satisfaction (on a scale of 0 to 10) were 7.5 in the German data and 7.0 in the British data.","Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","interview following the first birth (90 % in Germany, 88 % in Britain), but the majority of mothers were on a maternity or comparable leave (51 % in Germany, 55 % in Britain). At first interview, parents' levels of life satisfaction (on a scale of 0 to 10) were 7.5 in the German data and 7.0 in the British data. At first birth, life satisfaction was marginally higher, decreasing again by the last interview.","[2.0, 2.0, 1.0, 3.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41598-017-03627-7,Psychology_369,"In grownups, this interpersonal touch can help regulate responses to stress, increasing trust and emotional well-being.","In addition, a possible explanation for these contradictory findings may rely on the different definitions of synchronization used in the two studies.","It seems that hyperscanning, or this brain-to-brain coupling by the act of hand-holding while in pain, may have a soothing, analgesic effect, like the skin-to-skin touch that is beneficial to premature babies. In grownups, this interpersonal touch can help regulate responses to stress, increasing trust and emotional well-being. From fire-walking rituals and tear-jerker movies to choirs singing, and yes, the ultimate, googly-eyed love stares that make romantic couples, well, even more googly, researchers found evidence that women with highly empathetic partners reported increased pain reduction.","As a result they probably experienced higher levels of pain and distress during the pain condition, which may disrupt the physiological coupling. In addition, a possible explanation for these contradictory findings may rely on the different definitions of synchronization used in the two studies. Here we show that in the absence of touch, the experience of pain disrupted the physiological coupling as the targets probably were focusing on their own pain experience.","[1.0, 1.0, 2.0, 1.0, 1.0]",Psychology,train,1.2,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1186/s13229-018-0246-0,Psychology_37,"In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West.","In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000.","This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research."" In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","In Shenzhen, it was 42.3 per 10,000 and 19.0 per 10,000 in Jiamusi. In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000. The strengths of this first large-scale study of autism in China are several.","[4.0, 4.0, 5.0, 4.0]",Psychology,train,4.25,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1093/chemse/bjt066,Psychology_370,"When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label.",People react faster to food odors compared with nonfood odors ).,"When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.","However, edibility of the odorant could better explain our results. People react faster to food odors compared with nonfood odors ). This may explain why the positive label elicited a significantly faster reaction time than the negative one, as the latter was not associated with food.","[4.0, 2.0, 1.0, 1.0, 3.0]",Psychology,train,2.2,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1505114112,Psychology_371,But the benefits of music aren't just for musicians; taking up piano could be the difference between an A and a B in Spanish class.,"Synaptic density follows a similar developmental trajectory, increasing in early childhood and subsequently declining during adolescence (2-5).","At the end of 3 years, those students who had played instruments were better at detecting speech sounds, like syllables and words that rhyme, than their JROTC peers, the team reports online today in the Proceedings of the National Academy of Sciences. These findings suggest that musical training could keep that window open longer. But the benefits of music aren't just for musicians; taking up piano could be the difference between an A and a B in Spanish class.","Response consistency peaks in childhood (∼8-11 y of age), declining steadily until young adulthood ; we show that this adolescent decline is mitigated by in-school music lessons. Synaptic density follows a similar developmental trajectory, increasing in early childhood and subsequently declining during adolescence (2-5). Consistent with previous cross-sectional studies showing enhanced response consistency in musicians and in participants using assistive listening devices (75), the music training group maintained a higher level of response consistency between years 1 and 4.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://news.sciencemag.org/brain-behavior/2015/07/benefits-band-class
10.1177/0141076814565942,Psychology_372,"Experts Are Divided On Frisch's Study

Not all experts are convinced with Frisch's study that suggests circumcision could increase autism risk.",Older children whose foreskins have already spontaneously separated from the glans will only experience the pain associated with the foreskin incision.,"The study has also prompted the American Academy of Pediatrics to release a statement advising health facilities for newborns to use strategies that would lessen the number of painful procedures performed. Experts Are Divided On Frisch's Study

Not all experts are convinced with Frisch's study that suggests circumcision could increase autism risk. ""The problem with Frisch's fundamental premise is that circumcision causes pain in infants and boys,"" Morris pointed out.","5 The procedural pain associated with neonatal circumcision is plausibly more severe and the postoperative pain of longer duration than in older children and adults, because the foreskin of most neonates must be forcefully separated from the glans to which it is fused before it can be cut off. Older children whose foreskins have already spontaneously separated from the glans will only experience the pain associated with the foreskin incision. , , 4 Thus, while most boys presumably experience mild to moderate levels of pain and discomfort during and after the operation, some boys will endure strongly painful circumcisions.","[1.0, 2.0, 1.0, 1.0]",Psychology,train,1.25,news,http://www.parentherald.com/articles/44740/20160519/circumcision-increase-autism-risk-experts-divided.htm
10.1080/08870446.2013.818674,Psychology_373,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.","Coping planning showed an interaction with received social support for continuous abstinence (p< .05, see Table 2 , third column).","Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations. Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette).","Action planning did not show an interaction with received social support, neither for continuous abstinence nor for point prevalence (see Tables 2 and 3 , second column). Coping planning showed an interaction with received social support for continuous abstinence (p< .05, see Table 2 , third column). The analysis of the region of significance by the Johnson Neyman technique showed that the simple slopes were only significant at levels of social support higher than 1.65 (p < .05).","[4.0, 4.0, 4.0]",Psychology,train,4.0,news,http://www.healthcanal.com/substance-abuse/41119-rauchstopp-zu-zweit.html
10.1176/appi.ajp.2018.17111282,Psychology_374,The test is only supposed to provide some potentially useful information that people can discuss with their doctor.,The lack of blinding in two of the three studies also limits the validity of the meta-analysis.,"The 23andMe test will tell consumers about 33 genetic variants that are associated with how well common drugs -- blood thinners like Plavix and Coumadin, for example -- work, but it's explicit that consumers should not change their medications based on these results. The test is only supposed to provide some potentially useful information that people can discuss with their doctor. To win approval, the company had to run a demographically representative study proving that 97 percent of users understand that the test is not a medical recommendation, says 23andMe chief legal and regulatory officer Kathy Hibbs.","GeneSightguided treatment was most beneficial in patients receiving genotype-discordant (red-bin) medications at baseline, as might be expected. The lack of blinding in two of the three studies also limits the validity of the meta-analysis. In a 1-year, blinded, retrospective study, the number of outpatient health care visits, number of medical absence days, and number of disability claims were found to be significantly greater (p=0.015, p=0.04, and p=0.003, respectively) among patients treated with genotype-discordant medications (N=9; red bin) as compared with patients treated with genotype-concordant medications (N=39; green bin), equating to a total yearly savings of $5,174 .","[1.0, 1.0, 4.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1093/chemse/bjt066,Psychology_375,"However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive.","A possible explanation for this effect could be that the label ""cheap perfume"" is not truly negative or that it is less negative compared with other negative labels in the present study.","This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process. However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive. ""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu.","We found that participants rated geraniol as more intense when it was labeled positively (""fresh flowers"") than when labeled negatively (""cheap perfume""). A possible explanation for this effect could be that the label ""cheap perfume"" is not truly negative or that it is less negative compared with other negative labels in the present study. Further, geraniol was the only odor that was rated as pleasant when its ratings for positive and negative labels were collapsed together (although its negative label was neutral).","[2.0, 1.0, 1.0, 2.0]",Psychology,train,1.5,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/chemse/bjt066,Psychology_376,"""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","In addition to these subjective measures, pleasant and unpleasant odors have an impact on psychophysiological measures such as skin conductance, heart rate, startle reflex, and reaction time.","""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin -- which was rated positively when presented with the label ""Indian food"" -- did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","Therefore, its study will clarify whether an odor's edibility evaluation is also manipulated by a top-down process as is the case with pleasantness evaluation. In addition to these subjective measures, pleasant and unpleasant odors have an impact on psychophysiological measures such as skin conductance, heart rate, startle reflex, and reaction time. Skin conductance increases with unpleasant odors and decreases with pleasant odors .","[2.0, 1.0, 3.0, 5.0, 2.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1176/appi.ajp.2018.17111282,Psychology_377,"""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments.","CYP450-drug interactions were identified for 43 of these 54 patients, and other gene variants (COMT, OPRM1, SLCO1B1, VKORC1, and MTHFR) were deemed actionable for 33.","The doctor still isn't supposed to suggest changing medication until they have you genetically tested again by an independent lab. ""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments. The team analyzed four tests (CNSDose, Genecept, GeneSight, and Neuropharmagen) and found that they could reliably detect whether someone has a certain genetic variant, says Dunlop.","Prescribing changes were recommended for 54 (48%) patients after the IDgenetixinformed medication management review. CYP450-drug interactions were identified for 43 of these 54 patients, and other gene variants (COMT, OPRM1, SLCO1B1, VKORC1, and MTHFR) were deemed actionable for 33. In total, IDgenetixguided medication reviews identified the need for changes in medication regimen for 38% more patients than did standard methods.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1038/s41598-018-30980-y,Psychology_378,"Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children.""","For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 .","Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude. Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children."" As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits.""","If such were the case, REM in subsequent overnight sleep may support delayed emotional memory processing. For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 . Likewise, negative memories selectively cued during SWS are better remembered than uncued items 8 .","[2.0, 3.0, 2.0, 3.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_379,"However, in the long run, there are no differences between the happiness levels of men and women before and after children.","Rather, our results provide a new way of understanding theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by the subjective well-being response of parents to childbearing.","Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain. However, in the long run, there are no differences between the happiness levels of men and women before and after children. Those who have children at an older age or who are more educated have a particularly positive response to a first birth.","In addition, we do not argue that subjective well-being was the main driver of fertility decline because subjective experience likely became an important determinant of fertility during or after the second demographic transition with the rise of individualistic values. Rather, our results provide a new way of understanding theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by the subjective well-being response of parents to childbearing. Our results are quite similar in Britain and Germany.","[1.0, 2.0, 1.0]",Psychology,train,1.3333333333333333,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_38,Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample.,Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems.,"Among those with depression, researchers found a strong connection between the dorsolateral prefrontal cortex, which is associated with short-term memory; the precuneus, which is associated with the self, and the lateral orbitofrontal cortex, which is associated with negative emotion. Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[3.0, 3.0, 3.0, 4.0]",Psychology,train,3.25,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1111/cdev.12250,Psychology_380,What researchers found was that the kids considered cool in the 8th grade had already peaked by the time they reached high school.,"In addition, the sociometric assessment employed in this study limited raters to those from the same grade level (as do virtually all such assessments).","Allen said they chose to start at the age of 13 to catch the teens at the beginning of their adolescence. What researchers found was that the kids considered cool in the 8th grade had already peaked by the time they reached high school. For these teens, being popular was their highest goal, Allen said.","Similarly, the measure of valuing popularity, relying solely upon lay usage of the term, did not clearly distinguish between social preference versus social status in peer relationships. In addition, the sociometric assessment employed in this study limited raters to those from the same grade level (as do virtually all such assessments). In this case, however, the result is that if teens succeed in achieving popularity among older adolescents (but not among their age mates), our assessment would not have detected this effect.","[1.0, 1.0, 1.0, 5.0, 2.0]",Psychology,train,1.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1016/j.nicl.2013.09.001,Psychology_381,"""We empirically know that a certain type of anatomical abnormality is related to specific brain diseases,"" he said.","Of the 335 subjects with MRI scans at baseline, a total of 230 individuals remained cognitively normal and 51 developed incident cognitive impairment and were diagnosed with MCI (of these, 8 subsequently progressed to AD dementia).","Mori points out that such a ""biobank"" has the potential to impact doctors' workflow dramatically. ""We empirically know that a certain type of anatomical abnormality is related to specific brain diseases,"" he said. We hope our brain imaging data bank will not only assist such a learning process but also enhance the physician's ability to understand the pathology and reach the best medical decision.""","Over time, an additional number of subjects had developed MCI or AD dementia. Of the 335 subjects with MRI scans at baseline, a total of 230 individuals remained cognitively normal and 51 developed incident cognitive impairment and were diagnosed with MCI (of these, 8 subsequently progressed to AD dementia). Of the 230 controls who remained controls on follow-up, 136 had repeat MRI scans (M = 2.98/subject).","[3.0, 1.0, 3.0, 1.0]",Psychology,train,2.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1111/lcrp.12013,Psychology_382,"The team found that when the participants closed their eyes, they were able to remember 23 percent more information than the people in the other groups.",These findings provide support for the idea that visualization plays an important role in the eye-closure effect (see also .,"Close

If you're cramming for a test or have an important date to remember, you might find this simple tip useful: close your eyes. The team found that when the participants closed their eyes, they were able to remember 23 percent more information than the people in the other groups. Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer.","In contrast, eyeclosure had no significant effect on retrieval of auditory details. These findings provide support for the idea that visualization plays an important role in the eye-closure effect (see also . For participants who had not closed their eyes during the first session, eye-closure during the second free recall also significantly increased the report of incorrect visual information, which could have problematic consequences in legal settings.","[5.0, 5.0, 2.0, 3.0]",Psychology,train,3.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1093/chemse/bjt066,Psychology_383,The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels.,"Only the juniper berry odorant exhibited a difference in label fit: its positive label (""green mango"") (M = 2.60, SD = 2.17) fit significantly less, or was less representative, than its negative label (""hospital disinfectant"") (M = 6.70, SD = 2.67; t[9] = −3.69, P < 0.05, corrected).","When associated with a pleasant label, we enjoy the odour more than when it is presented with a negative label. The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.","In other words, all the labels (positive and negative) of these 4 odors equally represented the odors in question. Only the juniper berry odorant exhibited a difference in label fit: its positive label (""green mango"") (M = 2.60, SD = 2.17) fit significantly less, or was less representative, than its negative label (""hospital disinfectant"") (M = 6.70, SD = 2.67; t[9] = −3.69, P < 0.05, corrected). The other 4 labels fit well to the respective odors, as indicated by the mean values (range 4.5-9.1) of fit ratings (Table 2) .","[4.0, 3.0, 1.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1186/2045-5380-3-19,Psychology_384,"As a result, CBD helps restore balance, reducing the negative symptoms that ADHD sufferers experience, while also improving concentration.","Second, basal eCB signaling appears to be reduced in individuals afflicted with stress-related psychiatric conditions, such as major depression or PTSD, suggesting that impaired eCB signaling is related to the development of these conditions.","As a result, CBD eases the symptoms of many illnesses and contributes to better health and well-being. As a result, CBD helps restore balance, reducing the negative symptoms that ADHD sufferers experience, while also improving concentration. Using CBD, therefore, reduces the need for stimulants like Adderall.","First, eCB signaling is responsive to stress and deficient eCB activity is associated with increased stress responses, suggesting that eCB signaling constrains the magnitude of the stress response. Second, basal eCB signaling appears to be reduced in individuals afflicted with stress-related psychiatric conditions, such as major depression or PTSD, suggesting that impaired eCB signaling is related to the development of these conditions. Whether the reduction in eCB signaling is a predisposing factor or a burden of the disease itself, is yet to be determined, as is whether these changes in circulating eCB levels are reflective of central eCB activity.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1111/cdev.12250,Psychology_386,"By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement.",Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future.,"Meanwhile, as the young James Deans and Miley Cyruses aged they had to engage in ever-riskier behavior to keep thinking of themselves as cool. By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement. Turns out being a cool kid has a really short shelf life.","Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use. Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future. For example, if pseudomature behavior leaves early adolescents more likely to associate with deviant teens and more likely to believe that relying upon deviant behaviors is a useful way of impressing peers, then such behavior would likely place teens at greater risk of engaging in more serious deviant behavior going forward.","[2.0, 3.0, 4.0, 2.0, 5.0]",Psychology,train,3.2,news,http://www.scientificamerican.com/podcast/episode/cool-kids-age-poorly/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29
10.1186/s13229-018-0246-0,Psychology_387,"This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research.""",This is one of the reasons why previous prevalence estimates were much lower than those from the developed countries.,"This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research."" In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","Another limitation of this study was that there was no information available concerning the prevalence of autism in special education in Shenzhen and Jiamusi cities. This is one of the reasons why previous prevalence estimates were much lower than those from the developed countries. The prevalence in those two schools was 119 per 10,000 .","[1.0, 3.0, 1.0, 3.0, 3.0]",Psychology,train,2.2,news,http://ct.moreover.com/?a=38803735334&p=1pl&v=1&x=Olj8Q_8mSR67vcOaC9l--A
10.1002/eat.20625,Psychology_388,"The firm found that that was due to two things: the growing popularity of the size-acceptance movement, and dieter fatigue.","About one in five women and almost one in ten men acknowledged that they checked their body size at least ""very often"" during the past 3 months (a moderate effect).","Dieting is no longer a necessary problem of vanity, as it has been historically termed, but a problem of knowledge and efficiency--a rhetorical shift with broad implications for how people think of themselves. The firm found that that was due to two things: the growing popularity of the size-acceptance movement, and dieter fatigue. For new companies, laundering what are often fairly conventional diet practices through the language of technology provides the imprimatur of newness in the eyes of seasoned dieters, as well as a Trojan horse to reach consumers who, for whatever reason, were never interested in dieting qua dieting.","To our knowledge, ours is the first study to report gender differences in body checking or body avoidance in a community sample. About one in five women and almost one in ten men acknowledged that they checked their body size at least ""very often"" during the past 3 months (a moderate effect). Women were also significantly more likely than men to report consciously avoiding checking body weight or shape (a weak effect).","[2.0, 2.0, 2.0, 1.0, 1.0]",Psychology,train,1.6,news,http://ct.moreover.com/?a=37544034795&p=1pl&v=1&x=nSrZYazEZSBbGoNGR6w7Vg
10.1093/chemse/bjt066,Psychology_389,"However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive.","The relationship between labels with the ratings of intensity and reaction times seems to be more complex and modulated by a number of other factors, such as affective valence of odors (regardless of labels), label fit, and ""edibility"" of labels.","This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process. However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive. ""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu.","In summary, odor labels significantly affected perceived edibility and pleasantness, and there was a partial effect for odor labels on perceived intensity and reaction times. Odorants presented with positive labels were systematically rated as being more edible and more pleasant than negative labels, and this is true even for nonfood labels. The relationship between labels with the ratings of intensity and reaction times seems to be more complex and modulated by a number of other factors, such as affective valence of odors (regardless of labels), label fit, and ""edibility"" of labels.","[4.0, 1.0, 3.0, 4.0]",Psychology,train,3.0,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1093/schbul/sbv109,Psychology_39,"/ no comments

While it is known that the incidence and outward symptoms of schizophrenia are strongly influenced by ethnic factorsaEUR""for instance, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinationsaEUR""it was unclear if brain deficits would differ amongst suffers from various ethnic backgrounds.","For example, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations.","/ no comments

While it is known that the incidence and outward symptoms of schizophrenia are strongly influenced by ethnic factorsaEUR""for instance, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinationsaEUR""it was unclear if brain deficits would differ amongst suffers from various ethnic backgrounds. Building upon previous research showing consistent gray matter reduction in the right anterior insulaaEUR""evident after a single episode of the illnessaEUR""the authors conclude this reduction exists regardless of ethnic background. Their work provides additional evidence that this region may provide valuable information that could be used to inform diagnostic evaluations in not only schizophrenia but other Axis I disorders such as bipolar disorder, depression, addiction, obsessive-compulsive disorder and anxiety regardless of ethnicity.","the incidence and clinical expression of schizophrenia vary according to a number of sociodemographic factors including, amongst others, the ethnic origin of the patients under investigation. For example, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations. 5 In addition, the content of hallucination and delusions is also strongly influenced by the patient's ethnic milieus.","[5.0, 3.0, 5.0, 4.0]",Psychology,train,4.25,news,http://healthmedicinet.com/news/researchers-find-neuroanatomical-signature-for-schizophrenia/
10.1186/2045-5380-3-19,Psychology_390,"The overall effect is to bring the brain down from a state of over-stimulation to a normal, baseline stimulation level.","That is, stress-induced activation of the amygdala is reduced in those who have elevated AEA levels, and striatal responses to reward are higher.","This, in turn, helps improve focus and attention in those with ADHD. The overall effect is to bring the brain down from a state of over-stimulation to a normal, baseline stimulation level. It also has a high potential for abuse and misuse.","Interestingly, carriers of the A allele of this FAAH polymorphism exhibit blunted activation of the amygdala in response to threat cues and enhanced activation of the ventral striatum in response to reward-related cues . That is, stress-induced activation of the amygdala is reduced in those who have elevated AEA levels, and striatal responses to reward are higher. The reason for this putative discrepancy, and possible interactions with life stress, should be considered in future studies.","[1.0, 1.0, 3.0, 2.0, 1.0]",Psychology,train,1.6,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1080/09500693.2018.1540897,Psychology_391,"""Women are well-represented among student population, suggesting that the recruitment of women into STEM and academia more generally is going well,"" she says.","In future studies, a comprehensive view using the various aspects of the conceptual framework should be the basis for the design of programmes and experiments with them to prevent talented boys and girls from dropping out of STEM education.","The results are disheartening, lead author Dr. Whitney Beeler, MD, of the University of Michigan's Department of Radiation Oncology, tells Bustle. ""Women are well-represented among student population, suggesting that the recruitment of women into STEM and academia more generally is going well,"" she says. ""Unfortunately, it appears that the pipeline is leaking a with a consistent drop in the proportion of women at each rung of the professional ladder.","However, this knowledge can be more useful for the field of education if it results in actions focusing on increasing the interest and persistence in STEM education and STEM-related professions. In future studies, a comprehensive view using the various aspects of the conceptual framework should be the basis for the design of programmes and experiments with them to prevent talented boys and girls from dropping out of STEM education. No potential conflict of interest was reported by the authors.","[3.0, 3.0, 2.0, 4.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1177/0956797617692041,Psychology_392,Having to get refills did not seem to deter participants: People were just as likely to buy a large single serving as they were a somewhat smaller serving with refills.,Such norms can also be affected by the relative size of a serving container: A 20-oz drink seems smaller and more appropriate when it is the second-largest drink in a set as opposed to the largest .,"However, it did not affect the further downstream behavior of consumption. Having to get refills did not seem to deter participants: People were just as likely to buy a large single serving as they were a somewhat smaller serving with refills. Importantly, most of the people who chose to buy the drink with refills did end up getting a refill, and they tended to consume more overall: Participants consumed 44% more calories when they had a drink with refills than when they had a larger single drink.","This happens in part by shifting consumption normsthat is, people's views of an appropriate serving size . Such norms can also be affected by the relative size of a serving container: A 20-oz drink seems smaller and more appropriate when it is the second-largest drink in a set as opposed to the largest . And when large serving sizes are viewed as appropriate, people feel less guilty about consuming them, which can encourage overconsumption )-compounded by the tendency to underestimate the size of large serving containers ).","[3.0, 4.0, 2.0, 3.0, 4.0]",Psychology,train,3.2,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1016/j.jalz.2018.06.2856,Psychology_393,"""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine.","Some overlap existed across glaucoma, AMD, and DR, as 331 had two of these and 27 had all three conditions (Supplementary Figure) .","Cataract diagnosis was not an Alzheimer's disease risk factor. ""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye.""","At the data freeze, 213 participants had recent, and 481 had established glaucoma; 420 recent and 616 established AMD; 93 recent and 155 established DR; 741 recent and 2694 established cataract. Some overlap existed across glaucoma, AMD, and DR, as 331 had two of these and 27 had all three conditions (Supplementary Figure) . Most (87%) AMD codes did not specify wet versus dry.","[2.0, 1.0, 3.0, 2.0, 1.0]",Psychology,train,1.8,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1073/pnas.1322295111,Psychology_394,"In contrast, the other groups demonstrated a bias toward whichever color showed up most often in the trials.","On trials without personal control, near-misses and full-misses did not differ (t Subdividing the target group into the vmPFC, insula and amygdala subgroups, the overall task sensitivities were similar to the first model: the perceived chances of winning was higher on personal choice trials, and winning outcomes were rated as more pleasant and increased the motivation to continue the game.","Instead, they were likely to stick to the same color trial after trial. In contrast, the other groups demonstrated a bias toward whichever color showed up most often in the trials. The scientists believe that these results suggest where we might find some of the neural circuits that play a critical role in risky decision making.","Consistent with past observations with this task, the interaction was driven by the participant-chosen trials, on which near-misses tended to increase the motivation to continue playing (M = .2, SD = 29.2) compared to full-misses (M = 43.6, SD = 29.9), although this effect was marginally significant (t = 1.69, p = .10). On trials without personal control, near-misses and full-misses did not differ (t Subdividing the target group into the vmPFC, insula and amygdala subgroups, the overall task sensitivities were similar to the first model: the perceived chances of winning was higher on personal choice trials, and winning outcomes were rated as more pleasant and increased the motivation to continue the game. An additional effect was a further manifestation of the illusion of","[1.0, 2.0, 1.0, 1.0, 2.0]",Psychology,train,1.4,news,http://arstechnica.com/science/2014/04/brain-damage-can-make-people-immune-to-the-gamblers-fallacy/
10.1007/s10508-017-0962-0,Psychology_395,"rawpixels.com/Pexels

aVoice biasa might help explain why gay workers lose promotions and raises.","The same analysis conducted for the salary recommendation yielded a significant interaction between stimulus and sexual orientation, F(1, 59) = 4.89, p = .03, g p 2 = .08.","aTransitioning in the Workplacea shares advice about coming out to colleagues, introducing a new name and setting a medical timeline with your manager. It might get a little uncomfortable at work. rawpixels.com/Pexels

aVoice biasa might help explain why gay workers lose promotions and raises.","In contrast, when judging on the basis of voice, participants evaluated the heterosexual candidate (M = 3.63, SD = .76) more positively than the gay candidate (M = 2.16, SD = .83; p\.001). The same analysis conducted for the salary recommendation yielded a significant interaction between stimulus and sexual orientation, F(1, 59) = 4.89, p = .03, g p 2 = .08. While no significant difference emerged between the heterosexual (M = 1.36, SD = .49) and the gay candidate (M = 1.31, SD = .63) when their face was shown, in the voice condition the heterosexual candidate (M = 2.28, SD = 1.27) was assigned a higher salary than the gay applicant (M = 1.27, SD = .45; p = .001).","[1.0, 1.0, 4.0, 1.0, 3.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37397496941&p=1pl&v=1&x=Pw4ndUhTRs2bbpeJxg_bxQ
10.1093/jcr/ucw012,Psychology_396,"Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences.""",We also add to the growing body of literature exploring how consumers' online behavior can affect their self-concept .,"""In a sense, you become more like what the ads say you are. Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences."" They were also more likely to say they would purchase the Groupon than those in the other two groups.","Specifically, by showing that consumers viewing a behaviorally targeted ad recognize an implied label from a marketer, we integrate the literatures on marketplace metacognition and consumer response to firms' digital marketing efforts (e.g., . We also add to the growing body of literature exploring how consumers' online behavior can affect their self-concept . In addition, our work contributes to the literature on social labeling by introducing a new type of implied social label.","[2.0, 2.0, 2.0, 2.0]",Psychology,train,2.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1177/0141076814565942,Psychology_397,"The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency.","The HR was higher, though not significantly so, for boys circumcised at age 24 months or older (HR ¼ 1.96; 95% CI: 0.93-4.14), an estimate based on only seven cases of ASD in that group ( Table 2) .","That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces. The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency. At any rate, the findings may hold great promise for other countries to adopt formal anesthetic protocol to avoid, or at least minimize, the pain children experience.","For boys circumcised before their second birthday, overall ASD risk during the first 0-9 years of life was 41% elevated (HR ¼ 1.41; 95% CI: 1.05-1.90). The HR was higher, though not significantly so, for boys circumcised at age 24 months or older (HR ¼ 1.96; 95% CI: 0.93-4.14), an estimate based on only seven cases of ASD in that group ( Table 2) . The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) .","[3.0, 2.0, 3.0, 1.0]",Psychology,train,2.25,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1016/j.nicl.2015.02.009,Psychology_398,"""At the same time, it improves memory performance on a task that depends on the hippocampus.""","In each of the three aMCI cohorts, an area localized in the left DG/ CA3 subregion of the hippocampus showed significantly increased BOLD activation during lure trials correctly identified as similar when compared to control subjects (62.5 mg BID, t = 3.074, p = 0.004; 125 mg BID, t = −2.636, p = 0.013 and 250 mg BID, t = 2.070, p = 0.047) (Fig.","""What we've shown is that very low doses of the atypical antiepileptic levetiracetam reduces this over-activity,"" Gallagher said. ""At the same time, it improves memory performance on a task that depends on the hippocampus."" Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task.","Consistent with enrollment criteria, participants with aMCI scored significantly lower on immediate and delayed recall on tests of verbal and visual memory (Table 1) . In each of the three aMCI cohorts, an area localized in the left DG/ CA3 subregion of the hippocampus showed significantly increased BOLD activation during lure trials correctly identified as similar when compared to control subjects (62.5 mg BID, t = 3.074, p = 0.004; 125 mg BID, t = −2.636, p = 0.013 and 250 mg BID, t = 2.070, p = 0.047) (Fig. The aMCI participants in each cohort also had a similar profile in the 3-judgment memory task relative to aged-matched controls as assessed by the rates of each response option (old, similar, or new) on the critical lure trials.","[4.0, 1.0, 3.0, 3.0, 2.0]",Psychology,train,2.6,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1093/jcr/ucw012,Psychology_399,"""In a sense, you become more like what the ads say you are.","Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition).","It actually makes you feel more environmentally conscious and can change your behavior,"" said Rebecca Walker Reczek, co-author of the study and associate professor of marketing at The Ohio State University's Fisher College of Business. ""In a sense, you become more like what the ads say you are. Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences.""","The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label. Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition). However, participants in the behaviorally targeted condition recognized a label from the marketer as a result of this individual-level information matching to a greater extent than participants in the demographic targeting and nontargeting condition and demonstrated higher willingness to purchase the advertised product because of its consistency with this implied identity.","[2.0, 3.0, 4.0, 1.0, 1.0]",Psychology,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1186/s13229-018-0246-0,Psychology_4,"In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","Third, in all three cities, new cases of autism were identified by the study in mainstream schools, reflecting current under-diagnosis.","In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","Second, in Shenzhen and Jiamusi cities, where only mainstream data were available, prevalence is also in line with Western estimates . Third, in all three cities, new cases of autism were identified by the study in mainstream schools, reflecting current under-diagnosis. Finally, non-significant variation across different cities is seen indicating the need to explore potential variation of autism across diverse Chinese regions with large sample sizes to achieve a fully robust national picture.","[5.0, 4.0, 5.0, 5.0]",Psychology,train,4.75,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1111/cdev.12250,Psychology_40,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","These findings further support a cumulative continuity interpretation of results, in which pseudomature behavior is potentially altering key social contexts and behavioral patterns in ways that lead to greater future difficulties, even after accounting for the relatively minor nature and modest stabilities of the pseudomature behaviors themselves.","By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","These findings also suggest that the constellation of pseudomature behaviors examined was capturing something other than a simple propensity toward deviant behavior. These findings further support a cumulative continuity interpretation of results, in which pseudomature behavior is potentially altering key social contexts and behavioral patterns in ways that lead to greater future difficulties, even after accounting for the relatively minor nature and modest stabilities of the pseudomature behaviors themselves. In spite of the substantial long-term negative correlates of pseudomature behavior, the allure of such behavior to early adolescents was also easy to see within these data.","[3.0, 2.0, 5.0, 4.0, 2.0]",Psychology,train,3.2,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.3758/s13414-015-0969-3,Psychology_400,"""The stimulus-driven, reflexive attention and saccadic eye movement of those babies born via a Cesarean were found to be slowed compared to those of vaginally delivered infants.","Thus, irrespective of whether infants had to initiate a saccadic eye movement to a single item or to a stimulus item in the presence of a competing item, those who were delivered by caesarean section took longer to allocate attention and initiate that eye movement than did those who were delivered vaginally.","It is considered noteworthy since the number of C-sections in recent times has been increasing. ""The stimulus-driven, reflexive attention and saccadic eye movement of those babies born via a Cesarean were found to be slowed compared to those of vaginally delivered infants. This is not because such babies try to more accurately select the right cues.","3 , the interaction of target condition and birth experience was also not significant, F(1, 352) = 0.08, n.s., indicating that the differences in saccade latencies of vaginally delivered infants relative to infants delivered by caesarean section were similar when a target was presented alone (vaginal . Thus, irrespective of whether infants had to initiate a saccadic eye movement to a single item or to a stimulus item in the presence of a competing item, those who were delivered by caesarean section took longer to allocate attention and initiate that eye movement than did those who were delivered vaginally. Alternatively, the slowed attentional responses of caesarean-section infants relative to vaginal infants might have been due to other factors.","[4.0, 4.0, 5.0, 5.0]",Psychology,train,4.5,news,http://www.hngn.com/articles/118456/20150812/c-section-spatial-attention-birthing-procedure-affect-babys-ability-focus.htm
10.1016/j.amjmed.2014.02.007,Psychology_401,They found that all-cause mortality was significantly lower in the fourth quartile of muscle mass index compared with the first quartile.,The median age at the end of follow-up (or censoring) for those not known to have died was 80.6 years; 10 individuals were aged 100 years or more at the end of follow-up.,"Muscle allows the current to pass more easily than fat does, due to muscle's water content. They found that all-cause mortality was significantly lower in the fourth quartile of muscle mass index compared with the first quartile. ""Thus, rather than worrying about weight or body mass index, we should be trying to maximize and maintain muscle mass.""",The median age at death was 82.7 years; 7 individuals were aged 100 years or more at the time of death. The median age at the end of follow-up (or censoring) for those not known to have died was 80.6 years; 10 individuals were aged 100 years or more at the end of follow-up. Unadjusted all-cause mortality risk was significantly higher in the lowest muscle mass index quartile compared with the highest muscle mass index quartile (58% compared with 41%; relative reduction of 30%) ( Table 2 ).,"[1.0, 2.0, 3.0, 2.0, 2.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/03/140314095102.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2014.1208,Psychology_402,"The researchers suggest that women who reported more PTSD symptoms were more likely to have food addiction when measured via the Yale Food Addiction Scale, which assess dependency on food.",Food addiction prevalence appeared to be further elevated when PTSD symptoms occurred earlier in life.,"The researchers suggest that women who reported more PTSD symptoms were more likely to have food addiction when measured via the Yale Food Addiction Scale, which assess dependency on food. The researchers suggest that more than 50 percent of the participants were exposed to some type of trauma and about 66 percent women, who experienced trauma, reported to have at least one lifetime PTSD symptom. Around 8 percent of these women also reported to have between 6 and 7 PTSD symptoms, which was the maximum on the questionnaire they had filled.","In this analysis, we found a dose-response association between the number of lifetime PTSD symptoms and prevalence of food addiction in middle adulthood. Food addiction prevalence appeared to be further elevated when PTSD symptoms occurred earlier in life. To our knowledge, this is the first study to look at the association between PTSD symptoms and food addiction.","[5.0, 4.0, 3.0, 4.0]",Psychology,train,4.0,news,http://www.techtimes.com/articles/15875/20140918/women-with-ptsd-symptoms-with-higher-risk-of-food-addiction-study.htm
10.1111/cdev.12313,Psychology_403,"Despite romantic relationships being relatively new in adolescence, the better teens were at establishing autonomy and relatedness with partners at age 18, the better they were at establishing autonomy and relatedness with both friends and partners at age 21.","Greater autonomy and relatedness with close friends at age 13 significantly predicted greater autonomy and relatedness with romantic partners 5 years later, at age 18.","In addition, teens' abilities (or lack thereof) to express autonomy and maintain close relationships with friends and partners at age 18 predicted the degree of autonomy and closeness in future relationships at age 21. Despite romantic relationships being relatively new in adolescence, the better teens were at establishing autonomy and relatedness with partners at age 18, the better they were at establishing autonomy and relatedness with both friends and partners at age 21. ""Our study suggests that parents can promote or undermine teens' ability to assert their own views and needs to close friends and romantic partners.","Figure 2 illustrates significant cross-over cascade pathways between autonomy and relatedness with partners and friends. Greater autonomy and relatedness with close friends at age 13 significantly predicted greater autonomy and relatedness with romantic partners 5 years later, at age 18. In addition, age 18 autonomy and relatedness with close friends predicted relative increases (controlling for baseline levels) in autonomy and relatedness with romantic partners between ages 18 and 21.","[4.0, 3.0, 3.0, 5.0, 3.0]",Psychology,train,3.6,news,http://www.sciencedaily.com/releases/2014/10/141023091944.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1111/sode.12203,Psychology_406,"""Children who had their pet dog with them reported feeling less stressed compared to having a parent for social support or having no social support.""","Results supported the notion that pet dogs buffer children's perceived stress response; however, the results with children's cortisol response were more complex.","""Our research shows that having a pet dog present when a child is undergoing a stressful experience lowers how much children feel stressed out,"" Dr. Kertes said. ""Children who had their pet dog with them reported feeling less stressed compared to having a parent for social support or having no social support."" The results showed that for kids who underwent the stressful experience with their pet dogs, children's cortisol level varied depending on the nature of the interaction of children and their pets.","Dyadic interaction factors during the TSST-C were unrelated to perceived stress or cortisol assessed for baseline or recovery, indicating that dyadic interaction was linked only with the rise in cortisol during the TSST-C. Results supported the notion that pet dogs buffer children's perceived stress response; however, the results with children's cortisol response were more complex. The divergent finding for perceived stress and cortisol stress responses is not entirely unexpected, as perceived stress and neuroendocrine responses to stress are believed to be mediated by different cognitive and neurobiological pathways .","[4.0, 4.0, 4.0]",Psychology,train,4.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/WwCXTLBY4As/pet-dogs-children-04855.html
10.1001/jamapsychiatry.2018.2028,Psychology_408,The age adjusted association between PTSD and incident T2DM was significant.,"After adjusting for age, the cumulative incidence of T2DM was significantly higher in those with PTSD vs those without (patients with PTSD: 6.6%; patients without PTSD: 4.7%; P = .002); the same pattern occurred with respect to incidence rate (patients with PTSD: 15.2 per 1000 person-years; patients without PTSD: 11.4 per 1000 person-years; P = .01).","The average age of the patients was 42.8 years. The age adjusted association between PTSD and incident T2DM was significant. After adjusting for obesity, the association was reduced and no longer statistically significant.","Prior to adjusting for age, the T2DM cumulative incidence percent and incidence rates were similar in patients with PTSD (252 [7.3%]) and without PTSD (141 [6.4%]; P = .19). After adjusting for age, the cumulative incidence of T2DM was significantly higher in those with PTSD vs those without (patients with PTSD: 6.6%; patients without PTSD: 4.7%; P = .002); the same pattern occurred with respect to incidence rate (patients with PTSD: 15.2 per 1000 person-years; patients without PTSD: 11.4 per 1000 person-years; P = .01). After adjusting for age in model 2, PTSD was associated with a 33% increased likelihood of incident T2DM (hazard ratio [HR], 1.33; 95% CI, 1.08-1.64; P = .01).","[4.0, 3.0, 5.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34769166259&p=1pl&v=1&x=hwW0549hXYdj6FOtF9ESTw
10.1126/science.1238677,Psychology_409,This study shows that paternal care usually evolved after monogamy was already present.,"About half of all independent transitions to paternal care have occurred in instances where social monogamy was already established, whereas the evolution of paternal care occurred on the same branch as a transition to social monogamy in the other cases.","They showed that nine per cent of mammals are socially monogamous, including a few rodents, a number of primates, and some carnivores, like jackals, wolves, and meerkats. This study shows that paternal care usually evolved after monogamy was already present. This advance in understanding was, says Lukas, due to the volume of information they collected and the availability of genetic information that allowed the researchers to determine the sequence in which different traits evolved.","Although paternal care and social monogamy are associated, an analysis of transitions suggests that male care is probably a consequence rather than a cause of the evolution of social monogamy. About half of all independent transitions to paternal care have occurred in instances where social monogamy was already established, whereas the evolution of paternal care occurred on the same branch as a transition to social monogamy in the other cases. Inferences from BayesTraits' models indicate that paternal care is a secondary adaptation, because transitions to social monogamy are inferred to occur first on branches where both traits evolved separately (lrt P = 0.002; table S2).","[4.0, 4.0, 4.0, 5.0, 4.0]",Psychology,train,4.2,news,http://www.sciencedaily.com/releases/2013/07/130729172244.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamapsychiatry.2018.1941,Psychology_41,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""",The findings have implications for the treatment of depression and poor sleep quality.,"Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","An important finding was that the Depressive Problems scores in this general population were correlated with functional connectivities between areas, including the lateral orbitofrontal cortex, cingulate cortex, precuneus, angular gyrus, and temporal cortex. The findings have implications for the treatment of depression and poor sleep quality. 25 Specifically, the 123 items from Section VIII were administered (of which only 2 were on the topic of sleep quality).","[3.0, 5.0, 4.0, 3.0]",Psychology,train,3.75,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1073/pnas.1411228111,Psychology_410,"""Marijuana abusers show lower positive and higher negative emotionality scores than controls, which is consistent, on one hand, with lower reward sensitivity and motivation and, on the other hand, with increased stress reactivity and irritability,"" researchers wrote in the study.","The attenuated responses to MP, including reduced decreases in striatal DVs, are consistent with decreased brain reactivity to the DA stimulation in marijuana abusers that might contribute to their negative emotionality (increased stress reactivity and irritability) and addictive behaviors.","The findings revealed that marijuana users showed significantly lower dopamine responses compared to healthy controls, according to personality tests and brain scans. ""Marijuana abusers show lower positive and higher negative emotionality scores than controls, which is consistent, on one hand, with lower reward sensitivity and motivation and, on the other hand, with increased stress reactivity and irritability,"" researchers wrote in the study. ""We found that marijuana abusers display attenuated dopamine (DA) responses to MP, including reduced decreases in striatal distribution volumes.","In marijuana abusers, DA responses in ventral striatum were also inversely correlated with addiction severity and craving. The attenuated responses to MP, including reduced decreases in striatal DVs, are consistent with decreased brain reactivity to the DA stimulation in marijuana abusers that might contribute to their negative emotionality (increased stress reactivity and irritability) and addictive behaviors. ).","[5.0, 4.0, 4.0, 3.0, 4.0]",Psychology,train,4.0,news,http://www.counselheal.com/articles/10470/20140714/scientists-show-marijuana-up-anxiety-depression-risk.htm
10.1177/1557988315596224,Psychology_411,"This increase in BMI comes despite previous evidence of health benefits that come with fatherhood and to marriage, the study's authors note: Becoming a father generally inspires men to ""improve their diets, increase physical activity, decrease alcohol use, and lower risk-taking behavior,"" they say.","The majority of resident fathers in this study were married, an association in other research that has been reported to be advantageous in terms of education, income, and physical and mental health .","increase for a 6-foot-tall man over the study period--while the same-sized man being childless over the period was correlated with a lower BMI--a 1.4-lb. This increase in BMI comes despite previous evidence of health benefits that come with fatherhood and to marriage, the study's authors note: Becoming a father generally inspires men to ""improve their diets, increase physical activity, decrease alcohol use, and lower risk-taking behavior,"" they say. But, they add, the weight increase may be due to ""different kinds of foods, portions, and leftovers available; anecdotal evidence does exist of fathers cleaning their children's dinner plates.""","Prior research reports becoming a father is a time when men attempt to improve their diets, increase physical activity, decrease alcohol use, and lower risk-taking behavior ); yet the increase in this study is evidence that these changes in health behaviors may have little impact. The majority of resident fathers in this study were married, an association in other research that has been reported to be advantageous in terms of education, income, and physical and mental health . In this study, marriage is associated with increased BMI, findings supported by other work (albeit without regard for fatherhood status; .","[4.0, 1.0, 3.0, 4.0, 3.0]",Psychology,train,3.0,news,http://qz.com/459731/science-proves-that-the-dad-bod-is-real/
10.1093/cercor/bht266,Psychology_412,They found that both perception of spinning and eye-reflexes associated with activity of vestibular organs was reduced in dancers when compared to rowers.,Dancers' vestibular-reflex and perceptual responses to whole-body yaw-plane step rotations were: (1) Briefer and (2) uncorrelated (controls' reflex and perception were correlated).,Researchers found that the brains of ballet dancers get used to the spinning and suppress the information coming from the inner-ear organs. They found that both perception of spinning and eye-reflexes associated with activity of vestibular organs was reduced in dancers when compared to rowers. The MRI scans showed that brains of dancers were different from brains of rowers in two regions; the cerebellum and the cerebral cortex.,Dancers' vestibular-reflex and perceptual responses to whole-body yaw-plane step rotations were: (1) Briefer and (2) uncorrelated (controls' reflex and perception were correlated). Voxel-based morphometry showed a selective gray matter (GM) reduction in dancers' vestibular cerebellum correlating with ballet experience. Dancers' vestibular cerebellar GM density reduction was related to shorter perceptual responses (i.e.,"[4.0, 4.0, 2.0, 3.0]",Psychology,train,3.25,news,http://www.natureworldnews.com/articles/4198/20130927/ballet-dancers-spin-fast-due-changes-core-brain-regions.htm
10.1073/pnas.1902058116,Psychology_413,"They should encourage teenagers to stay active and turn off their phones at night--and perhaps more importantly, they should specifically ask about cyberbullying, since that seems to be a primary source of harm, Nicholls says.","We found that social media use is not, in and of itself, a strong predictor of life satisfaction across the adolescent population.","Takeaways for parents of teens are similar, she says. They should encourage teenagers to stay active and turn off their phones at night--and perhaps more importantly, they should specifically ask about cyberbullying, since that seems to be a primary source of harm, Nicholls says. ""The emphasis needs to now be on the mechanisms and the content,"" she says, ""rather than just black-balling social media.""","We found that social media use is not, in and of itself, a strong predictor of life satisfaction across the adolescent population. Instead, social media effects are nuanced, small at best, reciprocal over time, gender specific, and contingent on analytic methods. Furthermore, the volume of data under analysis, paired with unchecked analytical flexibility, enables selective research reporting, biasing the literature toward statistically significant effects (3, 4).","[2.0, 4.0, 3.0, 3.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=39952184341&p=1pl&v=1&x=4nchQYq8ortLFXiSzmOa9g
10.1001/jamapsychiatry.2018.2462,Psychology_414,"Diet, exercise, and alcohol use did not alter the link between depression and SLE, but depression remained strongly associated with the risk of incident SLE in models that further adjusted for BMI, cigarette smoking, and oral contraceptive and postmenopausal hormone use, whether at baseline only or using time-updated covariates.","Compared with women with no depression, women with a history of depression had a subsequent increased risk of SLE (HR, 2.67; 95% CI, 1.91-3.75; P < .001).","In a study model using the date of first symptoms to indicate the onset of SLE, the association of depression and SLE symptom onset was nearly identical to risk estimates from the main analysis. Diet, exercise, and alcohol use did not alter the link between depression and SLE, but depression remained strongly associated with the risk of incident SLE in models that further adjusted for BMI, cigarette smoking, and oral contraceptive and postmenopausal hormone use, whether at baseline only or using time-updated covariates. When compared with women who had no depression history, those with a history of it were more likely to be current cigarette smokers and to have used oral contraceptives and postmenopausal hormones but were less likely to exercise regularly.","During 20 years of follow-up, 145 cases of SLE occurred. Compared with women with no depression, women with a history of depression had a subsequent increased risk of SLE (HR, 2.67; 95% CI, 1.91-3.75; P < .001). Adjustment for body mass index, cigarette smoking, and oral contraception and postmenopausal hormone use slightly attenuated associations (adjusted HR, 2.45; 95% CI, 1.74-3.45; P < .001).","[4.0, 3.0, 4.0, 1.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=39707847210&p=1pl&v=1&x=wvXvyhIEdkGtFfwB5pLPpw
10.1007/s11121-013-0411-9,Psychology_416,Adolescent girls with more binge eating behaviors also reported more suicide attempts.,"In addition to high levels of internalizing problems, adolescents with binge-eating disorder also had high levels of suicide attempt and ideation.","These, in turn, predicted binge eating behaviors. Adolescent girls with more binge eating behaviors also reported more suicide attempts. The authors conclude: ""The relationships found in this study offer prevention scientists a unique opportunity to target individuals at high risk of psychiatric problems by intervening in the case of binge eating problems.","These results, along with those found with the present study, add credence to the idea of developing a universal prevention program aimed at lessening the incidence of binge eating along with a more individualized program targeted toward those at highest risk for internalizing problems along with binge-eating problems. In addition to high levels of internalizing problems, adolescents with binge-eating disorder also had high levels of suicide attempt and ideation. A possible explanation for these results is that the binge-eating problems are simply a way for individuals to cope with and manage their internalizing issues.","[5.0, 4.0, 5.0, 5.0]",Psychology,train,4.75,news,http://www.sciencedaily.com/releases/2013/07/130722123212.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1177/1948550616644299,Psychology_417,"Frequent selfie-takers' opinion of themselves (roughly 4.5/7 on the attractiveness scale, on average, and 5/7 on the likeability scale, on average) was higher than the opinions non-selfie-takers had of themselves (roughly 3.5/7 on the attractiveness scale, on average, and 4/7 on the likeability scale, on average.)","Thus, selfie-takers departed further from the external raters' objective perceptions of attractiveness than the non-selfie-takers did but only for impressions of their selfies (see Figure 1) .","The results of the study paint a picture of the generous views certain people have of themselves, compared to unbiased views that others have of how we present ourselves online. Frequent selfie-takers' opinion of themselves (roughly 4.5/7 on the attractiveness scale, on average, and 5/7 on the likeability scale, on average) was higher than the opinions non-selfie-takers had of themselves (roughly 3.5/7 on the attractiveness scale, on average, and 4/7 on the likeability scale, on average.) Serial-selfiers' opinions of themselves were even higher when compared to what other people thought of the frequent selfie-takers' photos (other people rated the frequent selfie-takers' images at roughly 3/7 on the attractiveness scale, on average, and 4/7 on the likeability scale, on average.)","This showed that the differences between the self-and others' ratings of selfies were significantly greater for selfie- .38 ], but that the differences between the selfie-takers (M ¼ 0.83, SD ¼ 1.66) and nonselfie-takers (M ¼ 0.51, SD ¼ 1.53) were about the same for the experimenter-taken photos, t(196) ¼ 1.40, p ¼ .16, r p ¼ .10, 95% CI [À.04, .24]. Thus, selfie-takers departed further from the external raters' objective perceptions of attractiveness than the non-selfie-takers did but only for impressions of their selfies (see Figure 1) . Analyzing the data separately for the targets' selfratings, we observed a significant main effect of Group, [.01, .29] , suggesting that selfie-takers and non-selfie-takers rated the attractiveness of their selfies and experimenter-taken photos differently.","[1.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,2.8,news,http://www.futurity.org/selfie-narcissism-1173752/
10.1016/j.jalz.2014.11.009,Psychology_418,"The MIND diet is also easier to follow than, say, the Mediterranean diet, which calls for daily consumption of fish and 3-4 daily servings of each of fruits and vegetables, Morris said.","The MIND diet is more similar to the DASH diet with regard to fish consumption, with an optimal serving of just one meal per week as opposed to six meals per week specified by the Mediterranean diet.","People with high adherence to the DASH and Mediterranean diets also had reductions in AD -- 39 percent with the DASH diet and 54 percent with the Mediterranean diet -- but got negligible benefits from moderate adherence to either of the two other diets. The MIND diet is also easier to follow than, say, the Mediterranean diet, which calls for daily consumption of fish and 3-4 daily servings of each of fruits and vegetables, Morris said. However, he or she must limits intake of the designated unhealthy foods, especially butter (less than 1 tablespoon a day), cheese, and fried or fast food (less than a serving a week for any of the three), to have a real shot at avoiding the devastating effects of AD, according to the study.","However, the MIND diet has a separate score component for berry consumption to reflect the positive associations reported between intakes of blueberries and strawberries and slower cognitive decline in the Nurses' Health Study . The MIND diet is more similar to the DASH diet with regard to fish consumption, with an optimal serving of just one meal per week as opposed to six meals per week specified by the Mediterranean diet. This level of fish consumption reflects the findings of prospective epidemiological studies that examined its relation to AD prevention .","[2.0, 3.0, 5.0, 3.0, 4.0]",Psychology,train,3.4,news,http://www.sciencedaily.com/releases/2015/03/150319104218.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_environment+%28ScienceDaily%3A+Top+Environment+News%29
10.1007/s13524-014-0321-x,Psychology_42,"""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.","Importantly, we observe that happiness increases before birth, suggesting that the happiness gain around the time of birth may capture not only the effect of the birth but also the complex childbearing process that may involve partnership formation, partnership quality, and increased sexual activity.","Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","Consistent with prior literature using longitudinal designs (e.g., , our results first document a temporary and transitory gain in happiness around the time of birth. Importantly, we observe that happiness increases before birth, suggesting that the happiness gain around the time of birth may capture not only the effect of the birth but also the complex childbearing process that may involve partnership formation, partnership quality, and increased sexual activity. We then analyze the patterns for different socioeconomic groups and parities and show that the changes in subjective well-being over the transition to parenthood are highly consistent with the low and late fertility behavior that has emerged during the second demographic transition: older parents and those with more socioeconomic resources have the strongest happiness gains around the time of birth, and the temporary happiness gain around the time of birth declines with the number of children that one already has.","[3.0, 4.0, 4.0, 5.0, 3.0]",Psychology,train,3.8,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s11121-017-0762-8,Psychology_421,"Among non-transgender women, bisexual women had higher odds of sexual assault than heterosexual women.","Transgender people had higher odds of sexual assault than cisgender men and women, and Black transgender people had significantly higher odds of sexual assault than White transgender people.","Among non-transgender men, gay and bisexual men had higher odds of sexual assault than heterosexual men, and black men had higher odds than white men. Among non-transgender women, bisexual women had higher odds of sexual assault than heterosexual women. Compared with white women, black women had higher odds of sexual assault, while Latino and Asian women had lower odds.","Our exploratory results indicated that sexual assault disproportionately affects several sexual, gender, and racial/ethnic minority subgroups. Transgender people had higher odds of sexual assault than cisgender men and women, and Black transgender people had significantly higher odds of sexual assault than White transgender people. Like in previous studies (American College Health Association 2012 , cisgender women had higher odds of sexual assault than cisgender men, but gender modified the effects of sexual identity and race/ethnicity on sexual assault.","[2.0, 2.0, 5.0, 3.0]",Psychology,train,2.0,news,http://healthmedicinet.com/news/sexual-assault-victimization-disproportionately-affects-certain-minority-college-students/
10.1016/j.jrp.2008.09.001,Psychology_422,"Extrinsic goals like money, fame, and image don't meet the psychological needs.","Third, our findings were correlational, so they do not provide evidence for the direction of effects among the constructs under investigation.","The difference in how these goals affect happiness comes down to needs. Extrinsic goals like money, fame, and image don't meet the psychological needs. On the other hand, intrinsic goals directly nourish psychological needs: Taking charge of your personal growth grants you a sense of autonomy, staying in shape is a way of mastering your body, and having awesome friendships gives you a sense of belonging.","Therefore, it is important to replicate these findings using a more diverse sample, especially among older working adults and post-retirement, elderly samples. Third, our findings were correlational, so they do not provide evidence for the direction of effects among the constructs under investigation. Therefore, we can conclude only that changes in aspiration attainment and psychological health were correlated, so future research could further examine the issue of directionality.","[1.0, 1.0, 1.0, 2.0]",Psychology,train,1.25,news,http://www.businessinsider.com/extrinsic-goals-are-an-obstacle-to-happiness-2014-7
10.1073/pnas.1510456112,Psychology_424,"In rats, raising FGF9 levels artificially led to depression-like behavior changes, and repeated social stress caused brain FGF9 levels to rise.","Specifically, FGF2 expression was reduced and FGF9 expression was elevated in the frontal cortices (3) and locus coeruleus (4) of the depressed brain relative to controls.","In this case, people with major depression had 32 percent more of FGF9 in a key part of their brain than people without the condition. In rats, raising FGF9 levels artificially led to depression-like behavior changes, and repeated social stress caused brain FGF9 levels to rise. Taken together, the findings provide more evidence that depression is a physical illness.","We uncovered a significant negative correlation between hippocampal FGF9 expression and FGF2 expression in postmortem hippocampal tissue, and this relationship may indicate that these transcripts work in functional opposition. Specifically, FGF2 expression was reduced and FGF9 expression was elevated in the frontal cortices (3) and locus coeruleus (4) of the depressed brain relative to controls. The negative correlations between FGF9 expression and other FGFs also underscore the biological significance of FGF9 dysregulation in affective disorders: these relationships indicate that FGF9 may be acting in a complex network of molecules, and the alterations in FGF9 expression are concurrent with changes in other FGF family members that we have previously observed to impact affective behavior.","[4.0, 4.0, 2.0, 3.0, 3.0]",Psychology,train,3.2,news,http://www.technology.org/2015/09/10/new-factor-depression-brain-protein-discovery-lead-better-treatments/
10.1001/jamapsychiatry.2016.3990,Psychology_425,Experts noted that participants with male or male-like brain anatomy were likely to have ASD regardless of their biological gender.,"Third, in future research, it will be crucial to further explore the functional relevance of our findings and to examine how normative sexrelated phenotypic diversity in brain structure relates to sex differences in general cognitive or behavioral profiles (eg, as shown by Miller and Halpern 40 and by Hyde 41 ) and to different clinical ASD phenotypes.","""We found that brain phenotype ranged from being typically female to typically male and that there is variability between these extremes,"" lead study author Christine Ecker said, via Fox. Experts noted that participants with male or male-like brain anatomy were likely to have ASD regardless of their biological gender. ""Our study demonstrates that normative sex-related phenotypic diversity in brain structure affects the prevalence of ASD in addition to biological sex alone, with male neuroanatomical characteristics carrying a higher intrinsic risk for ASD than female characteristics,"" study authors noted in their study, according to Medical Today.","While this scope is sufficient to provide proof of concept, it will be necessary in the future to extend our approach to other neurobiological features that have previously been linked to ASD (eg, cortical surface area and regional volumes 14 ) and to replicate our findings in other subgroups on the autism spectrum (eg, different age groups and individuals with learning disabilities). Third, in future research, it will be crucial to further explore the functional relevance of our findings and to examine how normative sexrelated phenotypic diversity in brain structure relates to sex differences in general cognitive or behavioral profiles (eg, as shown by Miller and Halpern 40 and by Hyde 41 ) and to different clinical ASD phenotypes. Our findings suggest that the neurobiological male phenotype carries a higher intrinsic risk for ASD than the female phenotype across the binary categories dictated by biological sex.","[4.0, 5.0, 4.0, 4.0]",Psychology,train,4.25,news,http://www.parentherald.com/articles/98258/20170210/autism-higher-boys-girls-male-brains-scientists-reveal-new-clues.htm
10.1177/1745691615617439,Psychology_426,"The Big Five personality dimensions show about 40-60 percent heritability rates, indicating that a sizeable portion of personality appears to be determined by genetic factors.","Heritability estimates for behavioral traits, typically between 30% and 50%, are by far the largest effect sizes in psychological science.","Of interest, concordance rates for identical twins reared apart were similar to those of identical twins raised together, suggesting the environmental influence was based on unshared environmental variables. The Big Five personality dimensions show about 40-60 percent heritability rates, indicating that a sizeable portion of personality appears to be determined by genetic factors. This area of study is complex and beyond the scope of this article, but the field is quickly progressing.","The most important reason for the reproducibility of behavioral genetic results is that genetic effect sizes are large. Heritability estimates for behavioral traits, typically between 30% and 50%, are by far the largest effect sizes in psychological science. In retrospect, it is amazing that inherited DNA differences can work their way through the complexities of pathways from genes to brain to behavior and end up accounting for so much of the variance of complex psychological traits.","[2.0, 3.0, 5.0, 2.0]",Psychology,train,5.0,news,http://ct.moreover.com/?a=39947760251&p=1pl&v=1&x=jzkKllJ8utZ58UzAeF9BQw
10.1093/cercor/bhu139,Psychology_427,The group that had been asleep were better at remembering the German translations of the Dutch words they had heard in their sleep.,Re-exposure to Dutch words during sleep improved later memory for the German translation of the cued words when compared with uncued words.,Half of the volunteers then went to bed. The group that had been asleep were better at remembering the German translations of the Dutch words they had heard in their sleep. The volunteers who had remained awake were unable to remember words they had heard on the playback any better than those they had not.,"Re-exposure to Dutch words during sleep improved later memory for the German translation of the cued words when compared with uncued words. Recall of uncued words was similar to an additional group receiving no verbal cues during sleep. Furthermore, verbal cueing failed to improve memory during active and passive waking.","[5.0, 4.0, 5.0, 4.0, 4.0]",Psychology,train,4.4,news,http://www.sciencedaily.com/releases/2014/06/140630093629.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s10071-013-0699-7,Psychology_428,But monkeys could still locate targets at masking levels for which they reported that no target had been presented.,"Instead, the monkeys did not perceive the target and reported that.","The animals performed the tasks very accurately when the stimuli were unmasked, and their performance dropped when visual masking was employed. But monkeys could still locate targets at masking levels for which they reported that no target had been presented. While these results cannot establish the existence of phenomenal vision in monkeys, the discrepancy between visually guided action and detection parallels the dissociation of conscious and unconscious vision seen in humans.","This shows that the monkeys were not responding randomly due to increased difficulty. Instead, the monkeys did not perceive the target and reported that. Neither the main effect of SOA nor the interaction of SOA and task was significant (SOA: F 5,44 = 1.24, P = 0.31; SOA x task: F 5,44 = 0.74, P = 0.60), which is consistent with the hypothesis that monkeys solved the task in the same manner across all SOAs.","[2.0, 3.0, 4.0, 1.0]",Psychology,train,2.5,news,http://www.sciencedaily.com/releases/2013/11/131119131442.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.sleh.2018.09.005,Psychology_429,"These effects of late-night tweeting were greater during away games than home games, according to the study published online Nov. 19 in the journal Sleep Health.",Twitter data may provide sleep and sports researchers with a new tool to examine the effects of late-night activity on a variety of outcome measures.,"After sending tweets during typical sleeping hours, a player's shooting percentage fell by 1.7 percent, and he had 1.1 fewer points and 0.5 fewer rebounds in the next day's game. These effects of late-night tweeting were greater during away games than home games, according to the study published online Nov. 19 in the journal Sleep Health. ""While this study is relevant to coaches everywhere, this is not a study about either Twitter or basketball,"" said study lead author Jason Jones, assistant professor of sociology at Stony Brook University in New York.","In summary, we have demonstrated a negative association between late-night tweeting and player outputs among professional athletes in the high-stakes, competitive environment of official NBA games. These findings may apply widely to other sports and other cognitive and behavioral outcomes. Twitter data may provide sleep and sports researchers with a new tool to examine the effects of late-night activity on a variety of outcome measures.","[4.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,3.4,news,http://ct.moreover.com/?a=37736270375&p=1pl&v=1&x=Bi01WM9UtwVxM5Bjp2wZWQ
10.1177/0141076814565942,Psychology_43,The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys.","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) . Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys. Among boys in Muslim families, ASD risk was also significantly elevated in those who were circumcised (HR ¼ 1.54; 95% CI: 1.03-2.31), based on 28 ASD cases in circumcised boys versus 160 cases in intact boys.","[3.0, 3.0, 3.0, 5.0]",Psychology,train,3.5,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1177/0305735611430081,Psychology_430,Choir members said they felt more connected with their community and had better social functioning in general.,"Participation in a choir or other group activity can increase their level of social interaction and potentially provide an additional social identity, which could have positive outcomes for their health and well being.","One person described the choir as a ""wonderful family."" Choir members said they felt more connected with their community and had better social functioning in general. These social outcomes could be particularly important for those suffering from chronic mental illness.","This research is particularly relevant for disadvantaged people -many of whom live in social isolation. Participation in a choir or other group activity can increase their level of social interaction and potentially provide an additional social identity, which could have positive outcomes for their health and well being. The IPA approach has been called the most psychological of the thematic analysis approaches, with a particular focus on the cognitions and emotions of participants , which makes it a suitable approach for the current study.","[4.0, 5.0, 4.0, 5.0]",Psychology,train,4.5,news,http://www.rawstory.com/rs/2013/07/21/choir-can-help-those-suffering-from-chronic-mental-illness-study/
10.1016/j.neuron.2013.12.025,Psychology_432,"Sleep allows the brain to reset, helping integrate, newly learned material with consolidated memories, so the brain can begin anew the next day.""","Thus, the interactions between cortex and hippocampus during sleep are most likely bidirectional Diekelmann and Born, 2010; , with up states in the cortex activating the hippocampus in a feedforward manner, prompting the hippocampus itself to feedback on the cortex with sharp-wave ripple complexes.","""During wake, learning strengthens the synaptic connections throughout the brain, increasing the need for energy and saturating the brain with new information. Sleep allows the brain to reset, helping integrate, newly learned material with consolidated memories, so the brain can begin anew the next day."" In fact, the reason why we don't forget how to play the piano after a night's rest is because active circuits are damped down less than those that weren't actively involved in learning.","Conversely, the cortical, semantic component of such memories would benefit from superposition and gist extraction, as is the case with nondeclarative memories, leading to an advantage for the signal at the expense of the noise in cortical circuits. Thus, the interactions between cortex and hippocampus during sleep are most likely bidirectional Diekelmann and Born, 2010; , with up states in the cortex activating the hippocampus in a feedforward manner, prompting the hippocampus itself to feedback on the cortex with sharp-wave ripple complexes. First, such models propose that sleep leads to a system-level transformation of memory representations and not just to a straightforward transfer from hippocampus to cortex.","[3.0, 5.0, 3.0, 3.0]",Psychology,train,3.5,news,http://www.scienceworldreport.com/articles/12142/20140113/sleep-price-pay-learning-new-shy-hypothesis.htm
10.1016/j.neuron.2014.08.020,Psychology_433,The team also noted how individual neurons were able to shift their sensitivity to a particular color and particular direction.,We focused on neurons that were both color and direction selective using the three-way ANOVA or showed significant color and direction tuning shifts (n = 71) during the DCM task (using different populations led to similar results).,"However, the LIP neurons did not respond at all when the monkeys were passively viewing the same images without performing the task. The team also noted how individual neurons were able to shift their sensitivity to a particular color and particular direction. For instance, when the monkeys looked for red dots moving upward, a neuron would respond strongly to dots moving in directions close to upward motion and colors close to red.","This raises a question about whether feature encoding in LIP is used to detect and respond to match stimuli. We focused on neurons that were both color and direction selective using the three-way ANOVA or showed significant color and direction tuning shifts (n = 71) during the DCM task (using different populations led to similar results). Responses to match stimuli ( Figure S2A ) were higher than for nonmatch stimuli for both sample A (paired t test, p = 4 3 10 À5 ) and B (p = 0.001) trials.","[5.0, 4.0, 4.0, 5.0]",Psychology,train,4.5,news,http://www.medicaldaily.com/how-your-brain-identifies-color-motion-such-football-jerseys-301244
10.1007/s10803-014-2093-y,Psychology_434,"Of the 95 participants with ASD, 78 per cent reported at least one occurrence of sexual victimization compared to 47.4 per cent of the 117 adults without ASD who participated in the study.","Most concerning is the potential that the combination of age appropriate sexual motivation and interest, limited sexual knowledge and experiences, and additional social deficits, may place adolescents and young adults with ASD at increased risk for sexual violence victimization.","The study, conducted by Weiss, and clinical developmental psychology PhD candidates Stephanie Brown-Lavoie and Michelle Viecili, found that the lack of sexual knowledge in adults with autism played a role in increasing the risk of sexual victimization -- experiences of sexual coercion, unwanted sexual contact, attempted rape or rape. Of the 95 participants with ASD, 78 per cent reported at least one occurrence of sexual victimization compared to 47.4 per cent of the 117 adults without ASD who participated in the study. Brown-Lavoie points out that the study participants were asked about specific situations, not just a general ""have you been sexually victimized"" question.","found that individuals with ASD were more likely to report television and ''by making mistakes'' in their list of sexual knowledge sources, and less likely to report social sources. Most concerning is the potential that the combination of age appropriate sexual motivation and interest, limited sexual knowledge and experiences, and additional social deficits, may place adolescents and young adults with ASD at increased risk for sexual violence victimization. Children with autism in the education system were not at an increased risk for sexual abuse compared to peers with other disabilities.","[4.0, 4.0, 4.0, 5.0]",Psychology,train,4.25,news,http://www.sciencedaily.com/releases/2014/08/140814192243.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0956797618772506,Psychology_435,The researchers discovered that receiving a thank-you note has a far bigger impact on people's happiness than the senders had assumed.,"These results again suggest that expressions of gratitude are guided by expectations about a recipient's reactions, with people choosing to express their gratitude to recipients who they believe will feel positive.",They gave strong fives all around. The researchers discovered that receiving a thank-you note has a far bigger impact on people's happiness than the senders had assumed. You think it needs to be eloquently written.,"Participants choice of whom to write a letter to followed these stated preferences: 31 (32% of the sample) wrote a gratitude letter to the person they expected would feel very positive, 25 (26%) to the person they expected would not feel awkward, 22 (22%) to the person they thought would be really surprised, 16 (16%) to the person they anticipated would not be surprised, 3 (3%) to the person would not feel positive, and only 1 (1%) to the person he or she expected would feel awkward when receiving it. These results again suggest that expressions of gratitude are guided by expectations about a recipient's reactions, with people choosing to express their gratitude to recipients who they believe will feel positive. Finally, participants reported feeling significantly happier than normal after expressing gratitude (M = 2.91, SD = 1.63), one-sample t(97) = 17.72, p < .0001, d = 1.79.","[3.0, 4.0, 4.0, 5.0, 2.0]",Psychology,train,3.6,news,http://ct.moreover.com/?a=34650334053&p=1pl&v=1&x=SChtcYVx5nwy-XPJPoR-AQ
10.1177/0956797614551370,Psychology_436,"When researchers then examined how these traits affected an individual's spouse, only conscientiousness made a difference either way.","These results suggest that people with conscientious spouses tend to emulate certain characteristics of their spouses (via their joint lifestyle), and that these characteristics, in turn, are positively associated with satisfaction at work and likelihood of being promoted.","For best results: Choose someone who's conscientious. When researchers then examined how these traits affected an individual's spouse, only conscientiousness made a difference either way. Unlike more inward-facing qualities such as neuroticism, conscientiousness affects those around you, inspiring successful behaviors to rub off onto a husband or wife.","Emulation explained the effect of partner conscientiousness on both job satisfaction, indirect effect = 0.004, 95% CI = [0.002, 0.006], and on job promotion, indirect effect = 0.004, 95% CI = [0.000, 0.008] (Table 4) . These results suggest that people with conscientious spouses tend to emulate certain characteristics of their spouses (via their joint lifestyle), and that these characteristics, in turn, are positively associated with satisfaction at work and likelihood of being promoted. Finally, we examined spillover of relationship satisfaction, and again we found that partner conscientiousness had a positive indirect effect on job satisfaction, point estimate = 0.014, 95% CI = [0.011, 0.017] (Table 4) .","[3.0, 3.0, 4.0, 2.0, 1.0]",Psychology,train,2.6,news,http://www.businessinsider.com/spouse-could-make-you-more-successful-2014-10
10.1038/s41562-018-0483-4,Psychology_437,"Mindset matters

""It's interesting that in the exercise study we saw a negative effect for those who were told they had the high-risk version, but in the eating study we saw a physiological improvement in people who were told they had the protective gene,"" Turnwald says.","While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype.","All indications were that the people were in worse shape than they were before learning of their fictitious genetic risk, in accordance with what participants were told about their genetic risk for exercise capacity. Mindset matters

""It's interesting that in the exercise study we saw a negative effect for those who were told they had the high-risk version, but in the eating study we saw a physiological improvement in people who were told they had the protective gene,"" Turnwald says. ""What was consistent in both studies was that those informed that they had the high-risk gene always had a worse outcome than those informed that they had the protective gene, even though we essentially drew out of a hat which information people received.""","The information itself provides a distinct psychological framework through which the individual interprets their current experience and prepares for future experiences and, as a result, this new mindset influences attention, motivation and, most interestingly, physiology in a manner that confirms their expectations 52 . While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype. Whether perceived risk elicits a negative effect or perceived protection elicits a positive effect is likely to differ depending on the gene of interest and the experimental paradigm.","[5.0, 5.0, 5.0, 5.0, 3.0]",Psychology,train,4.6,news,https://www.futurity.org/genetic-risk-physiology-1930122-2/
10.1016/j.neuropharm.2018.05.012,Psychology_438,"""It opens a therapeutic window of opportunity, in which people may have the ability to become less stuck to their normal patterns, be that thinking about yourself in a certain way as with depression, or taking substances.""",Three respondents reported attempting suicide.,"""Many other psychiatric disorders need to be examined, because there is good reason to think that when cautiously applied, psilocybin may have broad capabilities as a behavior change facilitator,"" he said. ""It opens a therapeutic window of opportunity, in which people may have the ability to become less stuck to their normal patterns, be that thinking about yourself in a certain way as with depression, or taking substances."" Despite these benefits, the researchers make it clear that the use of psilocybin is not without its risks--although these are greater in recreational rather than medical settings.","Three of the respondents reported their psilocybin use to be followed by the onset of enduring psychotic symptoms. Three respondents reported attempting suicide. As discussed in Factor 2, the risk of overdose poisoning by psilocybin is low due to its low physiological toxicity.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37244266641&p=1pl&v=1&x=QyzfD0tHAPZR74MROGoWZg
10.1186/s13229-018-0246-0,Psychology_44,"In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","First, results from Jilin City where both mainstream and special school data were available revealed a similar prevalence of autism in China to the West, at around 1% .","In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","There are four key findings from this study. First, results from Jilin City where both mainstream and special school data were available revealed a similar prevalence of autism in China to the West, at around 1% . Second, in Shenzhen and Jiamusi cities, where only mainstream data were available, prevalence is also in line with Western estimates .","[1.0, 2.0, 3.0, 1.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.3758/s13423-014-0794-z,Psychology_440,"Simple and familiar icons were the easiest to find, but when the task got harder, aesthetically appealing icons provided a performance boost that was not found for less-appealing visuals.","Replicating previous findings, visual complexity influenced icon localisation times, with simple icons found faster than complex icons overall (e.g.","The results of their study on how the aesthetic appeal of visuals enhances performance are published in SpringeraEUR(tm)s journal Psychonomic Bulletin Review. Simple and familiar icons were the easiest to find, but when the task got harder, aesthetically appealing icons provided a performance boost that was not found for less-appealing visuals. The researchers conclude that appealing icons are not only pleasant to use, but also speed up peopleaEUR(tm)s ability to solve multi-step problems with visuals when using websites or mobile phones.","Neither the Block × Appeal, not the Block × Complexity interactions were significant [F (8, 144) = 1.64, P > .05, ε 2 = .08; F (8, 144) = .54, P > .05, ε 2 = .02, respectively]. Replicating previous findings, visual complexity influenced icon localisation times, with simple icons found faster than complex icons overall (e.g. , the effect of visual complexity remained significant throughout the experiment (as evidenced by the lack of Complexity × Block interaction).","[4.0, 2.0, 4.0, 4.0, 4.0]",Psychology,train,3.6,news,http://healthmedicinet.com/news/study-finds-that-visually-pleasing-computer-graphics-enhance-user-performance/
10.1007/s11031-018-9698-y,Psychology_441,But perhaps the most important aspect of the study was that it showed how autonomy support leads to positive outcomes in employees.,"Overall, our findings lend support for autonomy support as a leadership approach that is consistent with self-determination and optimal functioning in work settings.","Interestingly, the study also showed that autonomy supportive approaches benefit employees irrespective of national culture--it is not just the way we like things to be in the West. But perhaps the most important aspect of the study was that it showed how autonomy support leads to positive outcomes in employees. The study suggests it helps employees satisfy three basic psychological needs--for autonomy, competence, and relatedness.","In addition, a meta-analytic path analysis supported motivational processes that underlie LAS and its consequences in workplaces. Overall, our findings lend support for autonomy support as a leadership approach that is consistent with self-determination and optimal functioning in work settings. LAS is characterized by leaders who take interest in the perspectives of their employees, provide opportunities for choice and input, encourage self-initiation, and avoid the use of external rewards or sanctions to motivate behavior.","[2.0, 5.0, 3.0, 5.0, 5.0]",Psychology,train,4.0,news,https://www.futurity.org/intrinsic-motivation-employees-managers-1792422-2/
10.1038/nature14618,Psychology_442,The researchers found that greater genetic diversity is actually linked to increased height.,"Likewise, the genomewide homozygosity effect on height cannot explain a significant proportion of the observed intergenerational increases .","Evolution doesn't stop for any creature-not even humans. The researchers found that greater genetic diversity is actually linked to increased height. Not only that, but greater genetic diversity is also associated with better cognitive skills, as well as higher levels of education.","Although increasing migration and panmixia have generated a secular trend in decreasing homozygosity , the Flynn effect, wherein succeeding generations perform better on cognitive tests than their predecessors , this cannot be explained by our findings, because the intergenerational change in cognitive scores is much larger than the differences in homozygosity would predict. Likewise, the genomewide homozygosity effect on height cannot explain a significant proportion of the observed intergenerational increases . Inbreeding depression, which arises from the effect of genome-wide homozygosity, is ubiquitous in plants and is seen for numerous fitnessrelated traits in animals , but we observed no effect for the 12 other mainly cardio-metabolic traits in which variation is strongly related to age.","[2.0, 2.0, 1.0, 2.0]",Psychology,train,1.75,news,http://www.scienceworldreport.com/articles/27380/20150702/evolution-humans-evolving-smarter-taller.htm
10.1093/geronb/gbx110,Psychology_443,"The results from more than 11,000 adults aged 51 and older show significant associations between cognitive function and volunteering among all participants, regardless of the amount of time spent.","While the repeated measurement of volunteer involvement is a significant benefit of these data, little is known about the nature of the volunteer work-information that would provide more rigorous tests of theory and likely lead to increased knowledge about which specific aspects of volunteer work are beneficial (or not) for older adults.","It's the brain's working memory and processing capacity that benefit the most from volunteering."" The results from more than 11,000 adults aged 51 and older show significant associations between cognitive function and volunteering among all participants, regardless of the amount of time spent. Adults with lower levels of education and women seemed to benefit the most.","It is also probable that those who volunteer self-select into the volunteer role, which might maximize the benefits of volunteering . While the repeated measurement of volunteer involvement is a significant benefit of these data, little is known about the nature of the volunteer work-information that would provide more rigorous tests of theory and likely lead to increased knowledge about which specific aspects of volunteer work are beneficial (or not) for older adults. The wave spacing (every 2 years) of the HRS also does not allow assessment of the waxing and waning in volunteer work that might occur in later adulthood ).","[2.0, 3.0, 3.0, 4.0, 3.0]",Psychology,train,3.0,news,http://www.futurity.org/volunteering-seniors-cognition-1575942/
10.1177/1745691615596788,Psychology_445,"""If parents have concerns about their teen's face-to-face social interactions or activities, they probably have more reason to be concerned about online activities,"" said George.",These types of observations have helped to spark an ongoing debate about how the digital age may be influencing identity development among young people.,"This may occur when adolescents struggling with existing relationships spent more time online. ""If parents have concerns about their teen's face-to-face social interactions or activities, they probably have more reason to be concerned about online activities,"" said George. Parent-adolescent relationships online also appear to mirror offline relationships, the authors found.","Far from corrupting the young, technology is seen to be creating a generation that is more open, more democratic, more creative, and more innovative than their parents' generation. These types of observations have helped to spark an ongoing debate about how the digital age may be influencing identity development among young people. Consistent with research on adolescent friendships, adolescents' online behaviors and presentations of self tend to closely mirror their offline activities, interests, and personalities.","[1.0, 4.0, 2.0, 4.0, 4.0]",Psychology,train,3.0,news,http://psychcentral.com/news/2015/11/19/parents-concerns-about-teen-use-of-social-media-and-cell-phones-generally-unfounded/95067.html
10.1016/j.cub.2014.05.075,Psychology_446,"""Our study shows that obesity may involve a specific impairment not in the processing of food itself, but rather in how obese individuals -- or at least obese women -- learn about cues in the environment that predict food,"" lead author Ifat Levy, assistant professor of comparative medicine and neurobiology at Yale School of Medicine, said in a press release.","The specificity of the decreased learning to the food domain and the fact that it was only observed in women suggest that it is not a learning impairment per se but rather a more complex interaction among food, gender, and learning.","Only one group seemed to be so distracted by food that they struggled with the task, and that group was explicitly obese women. ""Our study shows that obesity may involve a specific impairment not in the processing of food itself, but rather in how obese individuals -- or at least obese women -- learn about cues in the environment that predict food,"" lead author Ifat Levy, assistant professor of comparative medicine and neurobiology at Yale School of Medicine, said in a press release. ""Instead of focusing on reactions to the food itself, our results call for shifting attention to the way obese individuals learn about the environment and how they approach or ignore cues associated with food,"" the researchers wrote in the study.","Finally, the potentially higher incentive value of the monetary reward compared to the food reward could not account for the results because there was no main effect of reward modality on the composite learning measure or on individual indices. The specificity of the decreased learning to the food domain and the fact that it was only observed in women suggest that it is not a learning impairment per se but rather a more complex interaction among food, gender, and learning. Obese women, but not men, showed greater delay discounting and higher preference for immediate reward in the face of longer-term negative consequences, compared to their normal-weight counterparts, and these behavioral differences were associated with structural differences in striatum and dorsolateral prefrontal cortex .","[5.0, 2.0, 3.0, 4.0, 3.0]",Psychology,train,3.4,news,http://www.medicaldaily.com/food-impairs-learning-tasks-obese-women-researchers-say-what-these-new-findings-could-mean-obesity
10.1007/s00213-018-5049-7,Psychology_447,"For further information, please contact the cited source.",We hope this study will motivate future microdosing studies with more controlled designs to test this hypothesis.,"""Apart from its benefits as a potential cognitive enhancement technique, microdosing could be further investigated for its therapeutic efficacy to help individuals who suffer from rigid thought patterns or behavior such as individuals with depression or obsessive-compulsive disorder,"" she explains. Note: material may have been edited for length and content. For further information, please contact the cited source.","Based on these preliminary results, we speculate that psychedelics might affect cognitive metacontrol policies by optimizing the balance between cognitive persistence and flexibility. We hope this study will motivate future microdosing studies with more controlled designs to test this hypothesis. If similar, yet substantially more subtle, effects apply to microdosing, this would render microdosing a potentially interesting cognitive enhancer in healthy individuals or even the basis of a treatment strategy to tackle various disorders including depression.","[1.0, 1.0, 2.0, 2.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=37503819242&p=1pl&v=1&x=NRwj0T2A2FkeT-KTreQZvw
10.1111/cdev.12250,Psychology_45,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","Early adolescents engaging in high levels of pseudomature behavior will continue to be preoccupied with social status in new social venues (i.e., romantic relationships) as development progresses into early adulthood.","By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","3. Early adolescents engaging in high levels of pseudomature behavior will continue to be preoccupied with social status in new social venues (i.e., romantic relationships) as development progresses into early adulthood. Early adolescent pseudomature behavior will predict higher levels of future problems with alcohol and substance use and serious deviant behavior, even after accounting for early signs of such behavior.","[4.0, 3.0, 3.0, 2.0]",Psychology,train,3.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1111/acer.12200,Psychology_451,"""This is likely due to differences in social and gender norms for female drinkers compared to male drinkers,"" said study researcher Ash Levitt, a research scientist at the Research Institute on Addictions at the University at Buffalo, SUNY.",Conclusions: The findings suggest that gender differences in the application of intoxication terms are other-directed as well as self-directed and that intoxication language can inform gender-specific prevention and intervention efforts targeting problematic alcohol use among college students.,"In other words, people of both sexes tend to express women's drinking in moderate terms. ""This is likely due to differences in social and gender norms for female drinkers compared to male drinkers,"" said study researcher Ash Levitt, a research scientist at the Research Institute on Addictions at the University at Buffalo, SUNY. The drinking culture on campus may still make it seem that it is less acceptable for women to drink as much as guysdo, and women who drink a lot may be negatively perceived by other women and men -- this may be why women downplay even heavy drinking by using terms like ""tipsy"" to describe themselves, the researchers suggest.","Specifically, moderate intoxication terms were applied to and from women more than men, even when the character was heavily intoxicated, whereas heavy intoxication terms were applied to and from men more than women. Conclusions: The findings suggest that gender differences in the application of intoxication terms are other-directed as well as self-directed and that intoxication language can inform gender-specific prevention and intervention efforts targeting problematic alcohol use among college students. Understanding this language can provide critical insight into subjective perceptions of intoxicated states, particularly among specific groups in the general drinking population such as college students that demonstrate elevated levels of heavy episodic drinking and alcohol-related consequences.","[3.0, 4.0, 4.0]",Psychology,train,3.6666666666666665,news,http://www.livescience.com/38096-college-drinking-words-men-women.html
10.1038/s41386-018-0207-5,Psychology_452,"In addition to accounting for differences in gender and age, the study controlled for the effects of psychotic disorders and tobacco use that could be associated with Parkinson's independent of ADHD.","The prevalence of ADHD in the adult population of this study was 1.7% (31,769 patients of 1.92 million individuals), considerably less than CDC-estimated ADHD prevalence in children and adolescents of 11% in the United States and 8.3% in Utah based on 2011 data .","Using the UPDB, the U of U team compiled an ADHD population, consisting of 31769 patients, of which 4960 were prescribed stimulant medications (2716 received amphetamine salts, 1941 received methylphenidate, and 303 received both). In addition to accounting for differences in gender and age, the study controlled for the effects of psychotic disorders and tobacco use that could be associated with Parkinson's independent of ADHD. The team was not able to account for other factors that could contribute to the development of Parkinson's disease, including head trauma, brain injuries, and environmental toxins.","This is consistent with reported incidence of Parkinson's disease onset at ages 30-49 years of 1.4-3.0 per 100,000 person years . The prevalence of ADHD in the adult population of this study was 1.7% (31,769 patients of 1.92 million individuals), considerably less than CDC-estimated ADHD prevalence in children and adolescents of 11% in the United States and 8.3% in Utah based on 2011 data . This is likely due to the fact that in the past 40 years since ADHD was defined, awareness of a clinical diagnosis has increased and methods of identifying ADHD patients have become more efficient and precise.","[2.0, 2.0, 4.0, 1.0]",Psychology,train,2.25,news,http://ct.moreover.com/?a=37082742309&p=1pl&v=1&x=yGFi7aVnOKNhmYePcImVpg
10.1126/science.aaa3799,Psychology_453,"For instance, one group of infants saw a ball roll down a ramp and appear to be stopped by a wall in its path.","Further, infants' failure to learn about the new object shows that the enhanced learning in experiment 1 was not due to general arousal or novelty.","It is, she says, ""as though they are taking the occasion to try to figure something out about their world."" For instance, one group of infants saw a ball roll down a ramp and appear to be stopped by a wall in its path. Testing the surprise

When the researchers gave babies new information about a surprising ball, the babies learned that information significantly better.","Hence, violations of expectation enhanced learning only for the object involved in the violation event, not for unrelated objects. Further, infants' failure to learn about the new object shows that the enhanced learning in experiment 1 was not due to general arousal or novelty. When taught about an object that was completely perceptually novel (because it had never been seen before) but did not violate any expectations, infants showed no evidence of learning.","[3.0, 2.0, 3.0, 2.0]",Psychology,train,2.5,news,http://www.futurity.org/surprise-babies-learning-890352/
10.1177/1948550614534701,Psychology_455,That's why people can encounter a split second of uncertainty about another person's gender upon seeing their face.,"Thus, both biological and social factors may contribute to gendered differences in facial appearance.","And, yes, most faces do contain some ratio of overlap between these gender categories. That's why people can encounter a split second of uncertainty about another person's gender upon seeing their face. The results showed that the longer it took for the students to select the correct gender of a female politician's face, the less likely they were to say they would vote for that candidate.","In addition to these biologically determined cues, individuals can electively display and/or enhance their gendered appearance through culturally specific gender cues. Thus, both biological and social factors may contribute to gendered differences in facial appearance. Such parallel processing triggers the partial activation of multiple categories, and thus, a face that contains conflicting cues, such as a heavier brow (activating a male representation) paired with larger eyes (activating a female representation), might initially elicit partial commitments to multiple categories.","[4.0, 3.0, 2.0, 5.0, 4.0]",Psychology,train,3.6,news,http://www.minnpost.com/second-opinion/2014/05/voters-especially-conservatives-prefer-women-politicians-quickly-identifiable
10.1073/pnas.1414784111,Psychology_457,The results showed that women who were using hormonal contraceptives when they met their husband experienced a drop in marital satisfaction after they discontinued a hormone-based birth control.,Discontinuing HCs may interact with husbands' facial attractiveness because it recalibrates women's relationship satisfaction to be more sensitive to such cues.,"In fact, the pill may be altering how attractive a woman finds a man. The results showed that women who were using hormonal contraceptives when they met their husband experienced a drop in marital satisfaction after they discontinued a hormone-based birth control. But, what's interesting is that how their satisfaction changed depended on their husbands' facial attractiveness.","Given that HCs are thought to disrupt this circuitry, it makes sense that they would weaken the extent to which relationship satisfaction is sensitive to any cues of partner genetic fitness, including facial attractiveness. Discontinuing HCs may interact with husbands' facial attractiveness because it recalibrates women's relationship satisfaction to be more sensitive to such cues. Sexual satisfaction as measured here , in contrast, captures the extent to which partners derive physical pleasure from their sexual activities.","[2.0, 3.0, 2.0]",Psychology,train,2.333333333333333,news,http://www.healthcanal.com/sexual-health/57759-study-contraception-may-change-how-happy-women-are-with-their-husbands-more-fsu-news-florida-state-24-7.html
10.1177/0956797616672268,Psychology_459,"For example, if the slide showed a thief finding $1 bills in a car, the description might be consistent (e.g., ""He examined the bills, and saw they were all $1 bills""), neutral (e.g., ""He examined the bills and saw they were all US currency""), or inconsistent (e.g., ""He examined the bills and saw that they were all $20 bills"") with the slide show.","In a striking experiment, showed just how important noticing change can be for preventing misinformation effects.","""These findings are important because they help explain why misinformation effects occur sometimes but not at other times - if people notice that the misinformation isn't accurate then they won't have a false memory."" For example, if the slide showed a thief finding $1 bills in a car, the description might be consistent (e.g., ""He examined the bills, and saw they were all $1 bills""), neutral (e.g., ""He examined the bills and saw they were all US currency""), or inconsistent (e.g., ""He examined the bills and saw that they were all $20 bills"") with the slide show. True to a general misinformation effect, people were most likely to choose the misinformation response when the detail in the narrative was inconsistent with the slide show.","did not measure change detection directly, but reading times and postexperiment interviews of the subjects corroborated the discrepancy-detection principle, which predicts that noticing discrepancies substantially reduces misinformation effects. In a striking experiment, showed just how important noticing change can be for preventing misinformation effects. Critically, the fifth piece of misinformation was a blatant change that every subject was 672268P SSXXX10.1177/0956797616672268Misinformation and RemindingsPutnam et al.","[2.0, 4.0, 2.0]",Psychology,train,2.6666666666666665,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/XJ6hp-LjVqQ/
10.1016/j.jpeds.2017.10.028,Psychology_46,There was a positive relationship between corporal punishment and physical violence during a romantic relationship.,"There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship. Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[3.0, 1.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1111/acer.12524,Psychology_460,"""Adolescents who begin drinking at a younger age are at greater risk for later alcohol problems.","This specific example of a genetic variant that influences early drinking milestones, but not initiation, builds on twin and adoption study findings that genetic factors contribute to the development of adolescent alcohol-related problems, and environmental factors more strongly drive drinking initiation .","Results will be published in the October 2014 online-only issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View. ""Adolescents who begin drinking at a younger age are at greater risk for later alcohol problems. These data demonstrate that alcohol use during adolescence plays an important role in the subsequent development of AUDs in adulthood.""","Despite having an early role in the trajectory of drinking behaviors, the ADH1B variant was not associated with drinking initiation, consistent with the hypothesized mechanism of action that requires alcohol exposure . This specific example of a genetic variant that influences early drinking milestones, but not initiation, builds on twin and adoption study findings that genetic factors contribute to the development of adolescent alcohol-related problems, and environmental factors more strongly drive drinking initiation . Beyond demonstrating an early protective role of the ADH1B GA/AA genotypes in the development of these drinking behaviors, the results illustrate that reporting most or all best friends drinking was associated with attenuation of this genetic protection (Fig.","[3.0, 4.0, 2.0, 3.0]",Psychology,train,3.0,news,http://www.sciencedaily.com/releases/2014/09/140923161225.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.cub.2009.09.064,Psychology_461,"Fetuses can hear and respond to their mother's voices starting as early as the third trimester of pregnancy, and hearing those voices helps babies develop social, cognitive and emotional skills.",Adult-like processing of pitch intervals allows newborns to appreciate musical melodies and emotional and linguistic prosody .,"Interactions between babies and caregivers who sing to them encourages the sort of ""serve and return"" relationships that help develop the brain's neural connections, and babies who are exposed to music and rich language more generally develop better communication and sound processing skills as a result. Fetuses can hear and respond to their mother's voices starting as early as the third trimester of pregnancy, and hearing those voices helps babies develop social, cognitive and emotional skills. Once they're born, babies prefer the sound of their mother's voice to all others.","Adult-like processing of pitch intervals allows newborns to appreciate musical melodies and emotional and linguistic prosody . Although prenatal exposure to native-language prosody influences newborns' perception, the surrounding language affects sound production apparently much later . The French group preferentially produced cries with a rising melody contour, whereas the German group preferentially produced falling contours.","[2.0, 2.0, 4.0, 3.0, 4.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=33981080987&p=1pl&v=1&x=xohrOO5U8HRq39Mmpr85Pw
10.1016/j.jaac.2013.05.019,Psychology_463,"""At the same time, half of young adults with an ASD did become employed, including youth with more challenging levels of impairment.","Given expectations for continued growth in the number of young adults with an ASD entering adulthood, urgent consideration should be given to employment preparation that is consistent with the current labor market in order to facilitate employment and minimize costs to society.","""This study highlights the particular difficulty that youth with autism are having during the transition into adulthood, especially youth from poorer households who are more likely to be disengaged from the services needed to secure and maintain a job. ""At the same time, half of young adults with an ASD did become employed, including youth with more challenging levels of impairment. This finding gives us hope for what might be possible with more effective preparation for employment, transition practices and workplace supports.""","Strategies for improving employment outcomes might include providing work experiences during high school, deliberate matching of capabilities to job types during transition planning, attention to the vulnerabilities of disadvantaged youth with ASD during and beyond transition, and increased flexibility of institutional supports provided over the occupational life course. Given expectations for continued growth in the number of young adults with an ASD entering adulthood, urgent consideration should be given to employment preparation that is consistent with the current labor market in order to facilitate employment and minimize costs to society. Future research is needed to determine how training provided during secondary school, in addition to postsecondary vocational education and rehabilitation services, contributes to future employment.","[2.0, 4.0, 4.0, 4.0]",Psychology,train,3.5,news,http://www.sciencedaily.com/releases/2013/09/130904130405.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.neuron.2017.02.004,Psychology_464,"""We've done a good job of extending life span, but a poor job of extending our health span.","Therefore, discrepancies in reported daytime sleepiness in older adults-increases or decreasesappear to depend, at least in part, on the time of day and/or circadian preference of the individuals being compared.","Not according to the new article in Neuron. ""We've done a good job of extending life span, but a poor job of extending our health span. We now see sleep, and improving sleep, as a new pathway for helping remedy that.""","Nevertheless, daytime sleep propensity can be higher in healthy older relative to younger adults in the evening, when the circadian alerting signal is otherwise at its peak in young adults (M€ unch et al., 2005) . Therefore, discrepancies in reported daytime sleepiness in older adults-increases or decreasesappear to depend, at least in part, on the time of day and/or circadian preference of the individuals being compared. This is of further relevance given the fact of advances in circadian preference in older age, wherein older individuals shift to earlier wake times and earlier bed times .","[1.0, 3.0, 2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://www.futurity.org/deep-sleep-older-people-1394132/
10.1038/s41598-018-27468-0,Psychology_465,"Surprisingly, whether children were paired with a friend or a child that neither of them had nominated as a friend had no effect on their propensity to share.","In the same study, the children's behaviour was comparable to that of adult chimpanzees, who also shared with their interaction partners as long as both of them received the high-quality reward, while human adults acted prosocially, irrespective of the quality of their own reward 22 .","If one considers withholding resources from others as a competitive, masculine strategy and sharing as a cooperative, more feminine strategy, these results are a further piece of evidence for the ""masculinisation effect"" of prenatal testosterone. Surprisingly, whether children were paired with a friend or a child that neither of them had nominated as a friend had no effect on their propensity to share. ""Our results show that primary school children already have a strong inclination to benefit others.","However, since in our study both the donor and the recipient always received the same reward item, it is not clear whether the children's prosocial donations in our study were mainly motivated by a preference for equitable outcomes or not. In the same study, the children's behaviour was comparable to that of adult chimpanzees, who also shared with their interaction partners as long as both of them received the high-quality reward, while human adults acted prosocially, irrespective of the quality of their own reward 22 . We further found that the children's age had no effect on whether they acted prosocially or not, albeit the age range in our sample was rather small (6-9 years).","[3.0, 1.0, 4.0, 4.0, 3.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=34310461275&p=1pl&v=1&x=LqTNsaofjxDeummOICEv8w
10.1038/npp.2011.6,Psychology_466,"The results showed those who took the oil experienced less anxiety, difficulty and discomfort during their speech, compared to those who took a placebo.","The placebo group presented higher anxiety, cognitive impairment, discomfort, and alert levels when compared with the control group as assessed with the VAMS.","""CBD oil helps to promote general feelings of wellbeing, which often suffer in a world of hectic social and work schedules."" The results showed those who took the oil experienced less anxiety, difficulty and discomfort during their speech, compared to those who took a placebo. ""It absolutely worked for me,"" he says.","Pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alert in their anticipatory speech. The placebo group presented higher anxiety, cognitive impairment, discomfort, and alert levels when compared with the control group as assessed with the VAMS. The SSPS-N scores evidenced significant increases during the testing of placebo group that was almost abolished in the CBD group.","[4.0, 4.0, 5.0, 5.0, 3.0]",Psychology,train,4.2,news,http://ct.moreover.com/?a=37641979979&p=1pl&v=1&x=asiO4BuTk0QHsqv1P6OB7g
10.1177/0022146518754534,Psychology_467,Researchers found that increased spending on health care and increases in specialized care were both associated with longer life expectancy and less mortality in the countries studied.,"Identifying the extent to which these relationships reflect problems with drugs per se (e.g., toxicity, high risk of interactions with other medications) versus the prescribing practices of physicians will be critical to reducing the risks that prescription medicines pose to population health.","Researchers found that increased spending on health care and increases in specialized care were both associated with longer life expectancy and less mortality in the countries studied. But pharmaceutical industry expansion was linked to negative health effects. ""This study isn't the first to suggest prescription drugs can pose a health risk.","Research also is needed to better understand the negative relationships observed between pharmaceutical expansion and population health. Identifying the extent to which these relationships reflect problems with drugs per se (e.g., toxicity, high risk of interactions with other medications) versus the prescribing practices of physicians will be critical to reducing the risks that prescription medicines pose to population health. In conclusion, this study suggests that the medical expansion occurring in OECD countries since the 1980s has both positive and negative relationships with population health.","[1.0, 2.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=33616418950&p=1pl&v=1&x=0U2rH0yB3sUIgJeq8eyfiQ
10.1287/orsc.2015.0965,Psychology_468,"Across the board, we seem to perceive leaders as more charismatic when they fit with our gendered expectations.","To the extent that these interactions are perceived by followers as arising unprompted by the leader, one implication of our findings is that perceptions of agency and communality arise not only from men's and women's behavior but also from the social context in which those behaviors occur.","iStock On one level, that's evidence that gender stereotypes are alive and well and living in our offices. Across the board, we seem to perceive leaders as more charismatic when they fit with our gendered expectations. Just as we expect leaders of hierarchies to exhibit traits we associate with men, we expect leaders of more cohesive networks to ""strive for intimacy and solidarity"" -- traits we tacitly associate with women.","When applied to leadership, this means that when women enact the agentic behaviors necessary for leadership, they are penalized for being insufficiently communal, resulting in negative evaluations of their leadership abilities . To the extent that these interactions are perceived by followers as arising unprompted by the leader, one implication of our findings is that perceptions of agency and communality arise not only from men's and women's behavior but also from the social context in which those behaviors occur. However, it may be that leaders are perceived by the followers to be responsible for cultivating the social structure in their teams along centralized and cohesive dimensions.","[5.0, 3.0, 3.0]",Psychology,train,3.6666666666666665,news,http://www.businessinsider.com/demise-of-traditional-corporate-structures-shake-up-whos-on-top-2015-6
10.1111/adb.12082,Psychology_469,"The data, he said, point to neuro-developmental mechanisms that increase the risk of addiction.","Developmental cortical-temporal limbic dysfunction in mental illness may thus amplify nicotine's reinforcing effects and addiction risk and severity, even while producing cognitive deficits that are not specifically or substantially reversible with nicotine.","The evidence suggests that the vulnerability is an involuntary biological result of the way the brain is designed and how it develops after birth, rather than it being about a rational choice to use nicotine as a medicine,"" Dr. The data, he said, point to neuro-developmental mechanisms that increase the risk of addiction. Better understanding of those mechanisms could lead to better prevention and treatment strategies, especially among mentally ill smokers, Dr.","These findings represent the first prospective evidence demonstrating a causal link between disease processes in schizophrenia and nicotine addiction. Developmental cortical-temporal limbic dysfunction in mental illness may thus amplify nicotine's reinforcing effects and addiction risk and severity, even while producing cognitive deficits that are not specifically or substantially reversible with nicotine. Although this research has imparted neuroscientific credence to a medicinal value for nicotine use in schizophrenia, recently emerging data indicate that acute nicotine dosing has no cognitive therapeutic benefits for schizophrenic compared to nonschizophrenia smokers .","[3.0, 5.0, 3.0, 4.0, 2.0]",Psychology,train,3.4,news,http://www.sciencedaily.com/releases/2013/09/130927123306.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1001/jamapsychiatry.2018.1941,Psychology_47,"While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","This is the first study, to our knowledge, to examine the neural mechanisms underlying the association of depression with sleep, a topic of great interest, with a large sample (n = 1017).","Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.","More details are provided in the eTable 5 in the Supplement. This is the first study, to our knowledge, to examine the neural mechanisms underlying the association of depression with sleep, a topic of great interest, with a large sample (n = 1017). The results show that both poor sleep quality and depressive problems are significantly positively correlated with functional connectivities involving the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the cingulate cortex, and the precuneus.","[3.0, 3.0, 4.0, 3.0, 3.0]",Psychology,train,3.2,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1073/pnas.1808412115,Psychology_471,"Building on an existing body of research on music and childhood development, the authors pinpoint a specific way that piano lessons can help young children enhance their language processing skills.","As in the current study, far transfer is not common in training studies (e.g., ref.","Building on an existing body of research on music and childhood development, the authors pinpoint a specific way that piano lessons can help young children enhance their language processing skills. As kids' ears become trained to distinguish between different pitches and tones at the piano, Gabrieli explains, they also seem to get better at parsing subtle differences between spoken words, a key element of language acquisition. After six months, the groups showed no significant differences in general measures of cognitive ability -- things like IQ, memory and attention span -- but the piano group had distinguished itself in one key way.","In the current study, far transfer would apply to the effects of musical training on general cognitive measures. As in the current study, far transfer is not common in training studies (e.g., ref. Specifically, our failure to find a far transfer in general cognitive functions is consistent with other longitudinal studies of children trained with music .","[1.0, 2.0, 1.0, 1.0]",Psychology,train,1.25,news,http://ct.moreover.com/?a=34439145574&p=1pl&v=1&x=7Yn6zH4b_7Bw-P-Wu8bLvQ
10.1007/s10926-011-9302-8,Psychology_472,Workers and would-be workers with disabilities fare better in places where higher shares of the overall working-age population are employed.,"A greater emphasis needs to be placed on communicating to employers that people with disabilities can be effective, productive, and reliable employees; one approach would be to feature employed people with diverse disabilities as trainers or as participants in the training.","People with disabilities have higher employment rates in regions with tighter labor markets

Employment rates among prime-aged adults with disabilities in the 100 largest metropolitan areas range from 28 percent to 60 percent (Map 1). Workers and would-be workers with disabilities fare better in places where higher shares of the overall working-age population are employed. In fact, the highest employment rate among people with disabilities (60 percent in Madison, Wis.) is still below the rate for all working-age adults in Bakersfield, Calif. (70 percent), the region with the lowest employment rate among the 100 largest metro areas.","Organizations providing ADA and disability training to managers, supervisors, and human resources personnel need to expand their focus to emphasize not only legal requirements but also problem solving strategies, information resources, and concrete solutions to accommodation and disability issues. A greater emphasis needs to be placed on communicating to employers that people with disabilities can be effective, productive, and reliable employees; one approach would be to feature employed people with diverse disabilities as trainers or as participants in the training. Advice to employers should also include guidance on procedures they could implement to improve the accommodation process and ensure a more hospitable workplace for employees with disabilities.","[2.0, 4.0, 2.0, 2.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=34633010286&p=1pl&v=1&x=6CVW_4aodDlnQG-GKUuRjg
10.1186/2211-1522-1-4,Psychology_474,"Moreover, the researchers found participants who described themselves as playful also valued playfulness, humor, and a laid-bac attitude, a fun tendency, and creativity in their potential partner.",They argue that strengths are positively valued traits that enable the good life.,"""Therefore, this personality trait also seems important for the choice of partner -- at least more so than the partner having a degree, good genes or being religious,"" said Proyer in the press release. Moreover, the researchers found participants who described themselves as playful also valued playfulness, humor, and a laid-bac attitude, a fun tendency, and creativity in their potential partner. Interestingly, those who were in relationships assessed themselves as more playful compared to their single counterparts.",Research in positive emotions may serve as one example. They argue that strengths are positively valued traits that enable the good life. Strengths are psychologically fulfilling and contribute to the well-being of a person.,"[3.0, 4.0, 2.0, 1.0, 1.0]",Psychology,train,2.2,news,http://www.medicaldaily.com/looking-love-playfulness-ranks-high-personality-trait-most-desired-partners-325540
10.1073/pnas.1620350114,Psychology_475,"In revealing neural entrainment as a generalized strategy for improving sensitivity to informational peaks, this study takes significant steps toward advancing the understanding of human language and perception.",Entrainment to the speech envelope may reflect mechanisms specialized for auditory perception.,"""This study suggests that humans have the ability to follow perceptual rhythms and make temporal predictions in any of our senses."" In revealing neural entrainment as a generalized strategy for improving sensitivity to informational peaks, this study takes significant steps toward advancing the understanding of human language and perception. ""Although both groups showed the same level of entrainment in early visual regions, they displayed differences in frontal regions-this finding sets the stage for us to identify aspects of neural entrainment that are linked to the physical properties of the visual signal compared to aspects that appear only with linguistic knowledge,"" she says.","Despite immense variability across languages, people can learn to understand any human language, spoken or signed. Entrainment to the speech envelope may reflect mechanisms specialized for auditory perception. Alternatively, flexible entrainment may be a general-purpose cortical mechanism that optimizes sensitivity to rhythmic information regardless of modality.","[4.0, 3.0, 4.0, 2.0]",Psychology,train,3.25,news,http://www.futurity.org/speech-sign-language-rhythms-1454802/
10.1073/pnas.1409643111,Psychology_476,"For instance, in all cultures tested, high testosterone faces were judged to be more aggressive, and this is useful information when encountering strangers.""","Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization.","Also, Sugiyama said: ""In large-scale societies like ours we encounter many unfamiliar people, so using appearance to infer personality traits can help cope with the overwhelming amount of social information. For instance, in all cultures tested, high testosterone faces were judged to be more aggressive, and this is useful information when encountering strangers."" The UO's research there is looking at the impacts of culture change on Shuar health.","Surprisingly, preferences for exaggerated sex-specific traits are only found in the novel, highly developed environments. Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization. These data challenge the hypothesis that facial dimorphism was an important ancestral signal of heritable mate value.","[1.0, 4.0, 2.0, 5.0]",Psychology,train,3.0,news,http://www.sciencedaily.com/releases/2014/09/140923142733.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1177/0022146514533347,Psychology_477,"""Our findings demonstrate that where obesity is most prevalent, the difference in life satisfaction between the obese and non-obese is smaller for women and almost non-existent for men,"" he said.","In counties with higher levels of obesity, this difference virtually disappears (less than 1.5 percent separates the nonobese and severely obese, and the difference between the nonobese and obese is less than .5 percent).","""Think about the advertising we see on television or in magazines -- we are bombarded by images of thin women, and we are told that is the ideal,"" said Pendergast, who noted that the study offers a potential explanation for the exponential increase in obesity in the United States over the past 30 years. ""Our findings demonstrate that where obesity is most prevalent, the difference in life satisfaction between the obese and non-obese is smaller for women and almost non-existent for men,"" he said. ""The same relationship is likely to exist over time and, as such, the emotional cost and advantage of obesity and non-obesity, respectively, may be decreasing as the prevalence of obesity increases.","For men in low-obesity counties, there is little more than a 2 and 7 percentage point respective difference between the obese and nonobese, and severely obese and nonobese, in the likelihood of reporting high life satisfaction. In counties with higher levels of obesity, this difference virtually disappears (less than 1.5 percent separates the nonobese and severely obese, and the difference between the nonobese and obese is less than .5 percent). In other words, there is almost no emotional cost of obesity in terms of life satisfaction for men living in high-obesity counties.","[5.0, 5.0, 5.0, 3.0, 5.0]",Psychology,train,4.6,news,http://psychcentral.com/news/2014/05/30/where-you-live-influences-your-satisfaction-with-life/70561.html
10.1093/bjc/azy024,Psychology_478,"Meanwhile, the Wilson/Callaghan (1974-1979) generation expressed the highest levels of worry about robbery and mugging, which was a key concern for politicians, policy makers and journalists at the time.","8 Specifically, it suggests that from 1920 to the mid-1990s, there was little discussion of the notion of 'antisocial behaviour'.","For example, those who grew up under the leadership of Margaret Thatcher (1979-1990) or John Major (1990-1997) expressed the greatest level of worry about domestic burglary - the same generation who witnessed a dramatic rise in property crime during the 1980s. Meanwhile, the Wilson/Callaghan (1974-1979) generation expressed the highest levels of worry about robbery and mugging, which was a key concern for politicians, policy makers and journalists at the time. Responses to antisocial behaviours tell a similar story.","Meanwhile, those who spent their formative years under New Labour might be influenced by the heavy political emphasis on antisocial behaviour that became a conspicuous criminal justice policy directive. 8 Specifically, it suggests that from 1920 to the mid-1990s, there was little discussion of the notion of 'antisocial behaviour'. This is in keeping with our expectations since it emerged during the 1950 1952 1954 1956 1958 1960 1962 1964 1966 1968 1970 1972 1974 1976 1978 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 7 See also the Conclusion for further discussion on an analysis of cohorts based on crime rates.","[1.0, 4.0, 1.0, 2.0, 1.0]",Psychology,train,1.8,news,http://ct.moreover.com/?a=34748352029&p=1pl&v=1&x=Kq8PIXgzycIa7jsarzF31w
10.1177/1359105314567207,Psychology_479,Dr. Mirgain also believes that mindfulness can interrupt the negative thought processes that convince people to skip exercising.,In contrast to the case of altering unhealthy habits where mindfulness and habit might be opposing (e.g.,"""When we're fully absorbed, we experience things deeply and we're more likely to remember them."" Dr. Mirgain also believes that mindfulness can interrupt the negative thought processes that convince people to skip exercising. You can convince yourself you don't want to go to the gym and, even when you're there, you may think you're not doing very well.","This finding could potentially shed light on the relationship of mindfulness with habit. In contrast to the case of altering unhealthy habits where mindfulness and habit might be opposing (e.g. In that sense, it is non-evaluative and involves no other cognitive processing.","[2.0, 3.0, 4.0, 4.0]",Psychology,train,3.25,news,http://www.healthcanal.com/life-style-fitness/61537-using-mindfulness-to-increase-exercise-satisfaction.html
10.1177/0141076814565942,Psychology_48,"What's more, ""risk was particularly high for infantile autism before age 5 years.""","More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism.","Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years."" What's more, ""risk was particularly high for infantile autism before age 5 years."" That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces.","Ritual circumcision among Danish boys is linked to an overall 46-62% increase in ASD risk in the first 10 years of life, with the upper risk estimate obtained after restriction to the period with the most complete data. More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism. To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation.","[5.0, 4.0, 3.0]",Psychology,train,4.0,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1177/0956797614557866,Psychology_480,"And while arguments and (quieter) counter-arguments fly regarding the possible advantages of bilingualism, it might be the pragmatic stance that wins out: speaking more than one language means being able to order lunch far from home.","Indeed, the finding of a bilingual disadvantage can hardly be interpreted as indicating better executive control abilities in monolinguals.","What seems certain, then, is that bilingualism does help ward off dementia, whether by empowering the brain's executive system or for still unknown reasons. And while arguments and (quieter) counter-arguments fly regarding the possible advantages of bilingualism, it might be the pragmatic stance that wins out: speaking more than one language means being able to order lunch far from home. While researchers continue to investigate, there are obvious advantages to being a polyglot, even without the much-celebrated, intellectual boost it might provide.","A lack of this kind of abstracts could result from file drawing on the level of conference submission already. Indeed, the finding of a bilingual disadvantage can hardly be interpreted as indicating better executive control abilities in monolinguals. The only reasonable conclusions would be that, in the tested domain, there is no bilingual advantage and a Type-I error occurred.","[2.0, 3.0, 4.0, 2.0, 3.0]",Psychology,train,2.8,news,http://www.businessinsider.com/is-there-a-bilingual-advantage-2015-1
10.1016/j.tics.2013.12.011,Psychology_481,"Often they're our friends, they're fun to be around.",allow people to up-or down-regulate their emotional reaction to social stimuli.,"""There are people who are part-way up the scale, high enough to warrant an assessment for psychopathy, but not high enough up to cause problems. Often they're our friends, they're fun to be around. They might take advantage of us now and then, but usually it's subtle and they're able to talk their way around it.""","This spontaneous propensity is best measured using minimal instructions: ""please look at the movies carefully"" and relatively neutral actors as stimuli. allow people to up-or down-regulate their emotional reaction to social stimuli. Despite keeping the experience of the object of empathy constant (e.g.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34630652538&p=1pl&v=1&x=LAN8BqmBSlsbulH_EOY-Bg
10.1073/pnas.1321664111,Psychology_483,"""Unraveling the subjective bodily sensations associated with human emotions may help us to better understand mood disorders, such as depression and anxiety, which are accompanied by altered emotional processing, ANS activity, and somatosensation.""","We propose that consciously felt emotions are associated with culturally universal, topographically distinct bodily sensations that may support the categorical experience of different emotions.","""We conclude that emotional feelings are associated with discrete, yet partially overlapping maps of bodily sensations, which could be at the core of the emotional experience,"" the authors wrote. ""Unraveling the subjective bodily sensations associated with human emotions may help us to better understand mood disorders, such as depression and anxiety, which are accompanied by altered emotional processing, ANS activity, and somatosensation."" Additionally, the authors believe monitoring the topography of emotion-triggered bodily sensations might not only provide a unique research tool but also a biomarker for emotional disorders.","Statistical classifiers discriminated emotion-specific activation maps accurately, confirming independence of bodily topographies across emotions. We propose that consciously felt emotions are associated with culturally universal, topographically distinct bodily sensations that may support the categorical experience of different emotions. One-out linear discriminant analysis (LDA) classified each of the basic emotions and the neutral state against all of the other emotions with a mean accuracy of 72% (chance level 50%), whereas complete classification (discriminating all emotions from each other) was accomplished with a mean accuracy of 38% (chance level 14%) ( Fig.","[4.0, 3.0, 3.0, 3.0, 3.0]",Psychology,train,3.2,news,http://www.medicaldaily.com/what-our-emotional-geography-researchers-map-bodily-sensations-commonly-identified-feelings-266088
10.1007/s11482-009-9091-9,Psychology_485,"But one with all sorts of really nice universal goodies, tons of vacation, and low inequality is a nice place to live, and its residents are happier.","This study demonstrates that vacationers are happier, compared to non-vacationers, but a holiday trip does not add much to their happiness.","There is probably something to this, but on the other hand all the happiest countries also have phones and the internet. The obvious common-sense reaction to the happiness divergence between the Nordic countries and the U.S. is surely the right one. But one with all sorts of really nice universal goodies, tons of vacation, and low inequality is a nice place to live, and its residents are happier.","Holiday expectation ) and homesickness could be assessed for possible moderating effects. This study demonstrates that vacationers are happier, compared to non-vacationers, but a holiday trip does not add much to their happiness. Generally, there were no differences between vacationers' and non-vacationers' post-trip happiness.","[2.0, 2.0, 4.0, 1.0, 3.0]",Psychology,train,2.4,news,http://ct.moreover.com/?a=38809111132&p=1pl&v=1&x=Xu-cPMNODUn_KHXkUmdpag
10.1186/s12888-019-2064-0,Psychology_486,"The study also found unemployment and low education levels were factors that contributed to poor mental health, while women were also found to be more likely than men to suffer disorders.",Results highlight unmet mental health needs in the region.,"Around 83% reported they had not seen a mental health specialist in the previous three months, despite 58% reporting having mental health disorders. The study also found unemployment and low education levels were factors that contributed to poor mental health, while women were also found to be more likely than men to suffer disorders. Approximately 80-100,000 were killed and 500,000 were displaced.","Conclusion: This is the first study at the primary care level to investigate prevalence of MHDs among conflict-affected populations in the Northern Province, Sri Lanka. Results highlight unmet mental health needs in the region. Training intervention to integrate mental health services into primary care is planned.","[2.0, 2.0, 3.0, 1.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38898984664&p=1pl&v=1&x=PNyKj5y0mmTb9a9UN-DvDA
10.1016/j.jneb.2014.02.008,Psychology_487,"Based on the finding, the researchers suggest that only after vigorous physical activity adolescents should take sports drinks and energy drinks should be discarded as they offer no health benefits and rather escalate the risk of overstimulation of the nervous system.","Nonhierarchical models with sports drink consumption as the independent variable explained 4% to 19% of variance in health behaviors, and the nonhierarchical models with energy drink consumption as the independent variable explained 4% to 18% of variance in health behaviors.","""Among boys, weekly sports drink consumption was significantly associated with higher TV viewing; boys who regularly consumed sports drinks spent about one additional hour per week watching TV compared with boys who consumed sports drinks less than once per week,"" said lead author Nicole Larson, PhD, MPH, RDN, University of Minnesota. ""Boys who consumed energy drinks at least weekly spent approximately four additional hours per week playing video games compared to those who consumed energy drinks less than once per week."" Based on the finding, the researchers suggest that only after vigorous physical activity adolescents should take sports drinks and energy drinks should be discarded as they offer no health benefits and rather escalate the risk of overstimulation of the nervous system.","The overall F value for each model examined was statistically significant at P < .05. Nonhierarchical models with sports drink consumption as the independent variable explained 4% to 19% of variance in health behaviors, and the nonhierarchical models with energy drink consumption as the independent variable explained 4% to 18% of variance in health behaviors. Overall, sports and energy drinks were consumed regularly (at least 1/wk) by 37.9% and 14.7% of the adolescent sample, respectively.","[2.0, 2.0, 2.0, 4.0, 4.0]",Psychology,train,2.8,news,http://www.scienceworldreport.com/articles/14486/20140506/intake-of-sports-and-energy-drinks-tied-to-unhealthy-and-negative-behaviour.htm
10.1073/pnas.1900952116,Psychology_488,"Overall, blind and sighted participants organized animals in similar ways and agreed on which physical features were most likely to be observed within animal groups.","5 , bar graphs; S-to-S correlation coefficients, M = 0.53, SD = 0.09; B-to-S, M = 0.12, SD = 0.12; comparing B-to-S vs. S-to-S, t (38) = 12.11, P < 0.0001; B-to-B correlation coefficients, M = 0.18, SD = 0.09; comparing B-to-B vs. S-to-S, t (38) = 12.7,","Overall, blind and sighted participants organized animals in similar ways and agreed on which physical features were most likely to be observed within animal groups. For example, blind and sighted participants judged that dolphins are similar in shape to sharks and sloths are similar in texture to grizzlies. 15 out of 20 blind and 19 out of 20 sighted participants judged elephants to be bigger than rhinos.","The correlation between group matrices was smaller, although still significant (rho = 0.35, P < 0.0001), and blind participants' answers were significantly different from those of the sighted as well as more variable [ Fig. 5 , bar graphs; S-to-S correlation coefficients, M = 0.53, SD = 0.09; B-to-S, M = 0.12, SD = 0.12; comparing B-to-S vs. S-to-S, t (38) = 12.11, P < 0.0001; B-to-B correlation coefficients, M = 0.18, SD = 0.09; comparing B-to-B vs. S-to-S, t (38) = 12.7, A one-way ANOVA confirmed that the degree to which blind and sighted groups disagreed differed across dimensions [comparing B-to-S across shape, texture, color, F(2,56) = 4.73, P = 0.01].","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39281075617&p=1pl&v=1&x=iLZT5c10rrdrasEZqJvfsg
10.1038/tp.2013.50,Psychology_489,"David Amaral, research director of the MIND Institute and senior author of the paper, noted ""that much research remains ahead of us to identify the mechanisms by which the antibodies affect brain development and behavior.","In addition, although no significant differences in subscale or composite scores were noted for the Mullen Scales of Early Learning or the Vineland Adaptive Behavioral Scales, increased impairments in the stereotypical behavior subscale of the ABC were observed for children of mothers possessing antibodies reactive to LDH in any context (P ¼ 0.024), CRMP1 (trending toward significance; P ¼ 0.055), as well as combined reactivity to LDH and STIP1 (P ¼ 0.015), or LDH/STIP1/CRMP1 (P ¼ 0.007) in comparison to children with an ASD whose mothers lack IgG reactivity to these antigens.","Bauman adds that this unique interdisciplinary study requires a team of researchers with expertise in immunology, animal behavior and neuroscience thus ""highlighting the collaborative efforts that characterize research at the UC Davis MIND Institute."" David Amaral, research director of the MIND Institute and senior author of the paper, noted ""that much research remains ahead of us to identify the mechanisms by which the antibodies affect brain development and behavior. But, this program of research is very exciting, because it opens pathways to potentially predicting and preventing some portion of future autism cases.""","We also analyzed the Autism Diagnostic Observation Schedule and Social Communication Questionnaire behavior scales in the ASD group, but there were no significant associations found with any of the band patterns. In addition, although no significant differences in subscale or composite scores were noted for the Mullen Scales of Early Learning or the Vineland Adaptive Behavioral Scales, increased impairments in the stereotypical behavior subscale of the ABC were observed for children of mothers possessing antibodies reactive to LDH in any context (P ¼ 0.024), CRMP1 (trending toward significance; P ¼ 0.055), as well as combined reactivity to LDH and STIP1 (P ¼ 0.015), or LDH/STIP1/CRMP1 (P ¼ 0.007) in comparison to children with an ASD whose mothers lack IgG reactivity to these antigens. In addition, increased overall impairment was reflected in the composite ABC score for children of mothers reactive against LDH and CRMP1 (P ¼ 0.046) as well as LDH/STIP1/CRMP1 (trending toward significance; P ¼ 0.06).","[1.0, 5.0, 3.0, 3.0, 4.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130709094704.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13229-018-0246-0,Psychology_49,"In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","In Shenzhen City: 21,420 children were screened and 35 cases of autism were identified, resulting in a mainstream prevalence of 42 per 10,000 (95% CI 20-89).","In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","Results: In Jilin City, 77 cases of autism were identified from a total population of 7258, equating to a prevalence of 108 per 10,000 (95% confidence interval (CI) 89, 130). In Shenzhen City: 21,420 children were screened and 35 cases of autism were identified, resulting in a mainstream prevalence of 42 per 10,000 (95% CI 20-89). In Jiamusi City, 16,358 children were screened, with 10 autism cases being identified, with a mainstream prevalence of 19 per 10,000 (95% CI 10-38).","[3.0, 2.0, 4.0, 5.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1111/ajps.12118,Psychology_490,"Fortunately, this problem is avoided in the case of family, because parents can't determine gender of their child.","Under such a theory, it is possible that we would see a general liberal trend among those having daughters across many cases having a gendered component, specifically cases involving discrimination against women.","However, alternative factors, such as personal relationships or experiences, were largely ignored. Fortunately, this problem is avoided in the case of family, because parents can't determine gender of their child. ""Using new data on the family lives of U.S. Courts of Appeals judges, we find that, conditional on the number of children a judge has, judges with daughters consistently vote in a more feminist fashion on gender issues than judges who have only sons.","Under this theory, parents would want to protect their daughters from possible gender-based discrimination, resulting in increased progressive views on employment or pregnancy discrimination law. Under such a theory, it is possible that we would see a general liberal trend among those having daughters across many cases having a gendered component, specifically cases involving discrimination against women. (However, we might also see a conservative trend among reproductive rights or abortion cases.)","[2.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.technology.org/2014/10/14/judges-daughters-feminist/
10.1073/pnas.1512653112,Psychology_491,"Carmen Sandi remains cautious, since the study involved rats rather than humans; after all, brain function is just one of the many elements that influence social dynamics.",Here we show that trait anxiety directly influences social dominance in male outbred rats and identify an important mediating role for mitochondrial function in the nucleus accumbens.,"The study is also the first to show that the brainaEUR(tm)s energy metabolism influences the establishment of social hierarchies. Carmen Sandi remains cautious, since the study involved rats rather than humans; after all, brain function is just one of the many elements that influence social dynamics. aEURoeSocial interactions are immensely complex,aEUR says Sandi.",Here we show that trait anxiety directly influences social dominance in male outbred rats and identify an important mediating role for mitochondrial function in the nucleus accumbens. High-anxious animals that are prone to become subordinate during a social encounter with a low-anxious rat exhibit reduced mitochondrial complex I and II proteins and respiratory capacity as well as decreased ATP and increased ROS production in the nucleus accumbens. A causal link for these findings is indicated by pharmacological approaches.,"[2.0, 3.0, 4.0, 1.0, 2.0]",Psychology,train,2.4,news,http://healthmedicinet.com/news/how-anxiety-can-kill-your-social-status/
10.1038/s41598-019-39932-6,Psychology_492,"Despite the bears' preference in the wild for a solitary life, the bears in this study took part in hundreds of play bouts, with more than twice as many gentle play sessions compared to rough play.","However, this possibility requires further research into whether gentle play is more likely to transition into rough play when exact facial mimicry occurs.","In the wild, it's a relatively solitary animal, so this suggests the ability to communicate via complex facial expressions could be a pervasive trait in mammals, allowing them to navigate their societies."" Despite the bears' preference in the wild for a solitary life, the bears in this study took part in hundreds of play bouts, with more than twice as many gentle play sessions compared to rough play. The bears were most likely to show precise facial mimicry during gentle play.","Perhaps exact facial mimicry helps to signal a readiness to transition into rougher play in sun bears, which is consistent with the proposition that facial communication helps regulate high play intensity 22 , and is a pattern previously associated with canid play signalling 19 . However, this possibility requires further research into whether gentle play is more likely to transition into rough play when exact facial mimicry occurs. Alternatively, exact facial mimicry might be more directly linked to gentle www.nature.com/scientificreports www.nature.com/scientificreports/ play and hereby function, for instance, to strengthen social bonds 24 .","[3.0, 4.0, 3.0, 2.0, 3.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=38812382548&p=1pl&v=1&x=TOdwIEJm_kqsQVy3uAw-PQ
10.1016/j.conb.2017.05.002,Psychology_493,This discovery may well prove to be the basis for enhancement treatments to reduce required sleep time in the years ahead.,"Not surprisingly, staying awake for extended periods of time leads to substantial wakedependent changes in cortical and subcortical network activity [9 ,10 ,11 ], which likely contribute to wellknown behavioural deficits after sleep deprivation or disruption .","We would accomplish much more, experience much more. This discovery may well prove to be the basis for enhancement treatments to reduce required sleep time in the years ahead. We should consider the caveats, however: sleep appears to be important in clearance of some aggregates from the brain, and it could be the case that individuals who sleep less have raised rates of neurodegenerative disease in late life, but these possible risks and associations have not yet been evaluated.","Furthermore we suggest that sleep disturbance may fundamentally change the nature of behaviour, making it more model-free and habitual as a result of reduced attentional capacity. Not surprisingly, staying awake for extended periods of time leads to substantial wakedependent changes in cortical and subcortical network activity [9 ,10 ,11 ], which likely contribute to wellknown behavioural deficits after sleep deprivation or disruption . Such opposing effects of waking and sleep on brain activity and behaviour may be described conceptually within a framework of homeostatic regulation .","[2.0, 4.0, 4.0]",Psychology,train,3.333333333333333,news,http://ct.moreover.com/?a=40256702740&p=1pl&v=1&x=U7YrUiGDxao-DC9rSXDtxQ
10.1002/erv.2553,Psychology_494,"To mitigate these long-term negative effects, we must recognise disordered eating early and direct sufferers to treatment,"" says Karkkainen.",Signs and symptoms of an eating disorder should always be taken seriously and not dismissed or minimized.,"""These results prove that disordered eating is detrimental to the physical and mental health of young adults both in the short and long term. To mitigate these long-term negative effects, we must recognise disordered eating early and direct sufferers to treatment,"" says Karkkainen. Eating can also be considered disordered if a person meticulously plans each meal long into the future, counts calories and weighs foods, follows an excessively strict diet or cuts certain foods from their diet claiming health or ethical reasons, when the real motivation is weight loss.","On average, the BMI of individuals with AN is lower than the BMI of those with BN, which is lower than the BMI of those with BED. Signs and symptoms of an eating disorder should always be taken seriously and not dismissed or minimized. Immediate attention is warranted, and a comprehensive evaluation should be the first step in treatment planning (American Psychiatric Association, 2006; National Collaborating Centre for Mental Health, 2004 ).","[3.0, 3.0, 5.0]",Psychology,train,3.6666666666666665,news,http://healthmedicinet.com/news/disordered-eating-among-young-adults-found-to-have-long-term-negative-health-effects/
10.1038/mp.2015.193,Psychology_495,"These effects not only evoke video games, but may also bother those prone to epileptic seizures.","However, the present study advanced our understanding of VGP as a daily habit of children and revealed that the conditions in which children play videogames for long periods of time may lead to unfavorable neurocognitive development, at least from a certain perspective.","Not only can gamers now seek treatment, but more therapists could provide specialized care and insurance companies could even cover the disease. These effects not only evoke video games, but may also bother those prone to epileptic seizures. Let's hope the WHO's new crusade will convince video game designers to do the same.","Thus our study cannot directly explain how MD correlates of the amount of VGP in the identified areas are associated with the observed cognitive functional correlates of the amount of VGP and other cognitive functions. In conclusion, increased VGP is directly or indirectly associated with delayed development of the MD in extensive regions in the brain as well as verbal intelligence. However, the present study advanced our understanding of VGP as a daily habit of children and revealed that the conditions in which children play videogames for long periods of time may lead to unfavorable neurocognitive development, at least from a certain perspective.","[3.0, 2.0, 2.0, 2.0, 4.0]",Psychology,train,2.6,news,http://ct.moreover.com/?a=34334814850&p=1pl&v=1&x=3LIsB4YcHB2ULIZrEip3Bw
10.1086/674724,Psychology_497,"It's far from simple, however.",.001).,"""Although happiness from extraordinary experiences does not change over one's lifespan, ordinary experiences elicit greater happiness as people get older and their remaining time becomes limited,"" they conclude in their study. It's far from simple, however. And there was a surprisingly high agreement over what kind of events made them the happiest.","Self-defining experiences (M p 7.36; SD p 1.68) were also associated with greater happiness than general experiences (M p 6.40; SD p 2.30; F(1, 315) p 29.04, p ! .001). A regression analysis showed a main effect of condition with self-defining experiences being more extraordinary (b p .61, t(315) p 4.51, p !","[1.0, 1.0, 1.0, 2.0]",Psychology,train,1.25,news,http://abcnews.go.com/Technology/happy-age/story?id=22635399
10.1111/bjop.12025,Psychology_498,The gum-chewing group was able to recall more of these numbers and even recall them more quickly than the group which was not allowed to chew gum.,The proposition is supported if the gradient of decline for the no-gum group is significantly steeper than that for the chewing-gum group.,A small group of 40 volunteers were able to better remember sequences when they were chewing gum than those who were not masticating. The gum-chewing group was able to recall more of these numbers and even recall them more quickly than the group which was not allowed to chew gum. The researchers also noted the gum chewers' performance increased over time as their reactions came quicker as the 30-minute test came to a close.,"Specifically, independent regression analysis for each participant in the no-gum and chewing-gum groups provides an estimate for their gradients of vigilance decline across epochs. The proposition is supported if the gradient of decline for the no-gum group is significantly steeper than that for the chewing-gum group. The computed gradients of decline (see Figure 2) were compared via an independent samples t-test and, consistent with the proposition, the gradient of decline for the no-gum group exceeded that for the chewing-gum group, (t(38)=3.99, p< .001: regression means = -0.32 and -0.06, for the no-gum and chewing-gum group, respectively).","[3.0, 4.0, 3.0, 4.0]",Psychology,train,3.5,news,http://www.redorbit.com/news/health/1112814380/gum-chewing-can-help-your-brain-040213/
10.1177/0190272516656585,Psychology_499,"In addition to potential efforts in schools to stop cyberbullying, Felmlee said parents can also take steps to mitigate cyber aggression in their children's lives.",Time 2 cyber aggression is 4.3 times more likely to occur between Time 1 friends (or former friends) than between friends of friends.,"""Our study calls attention to the role of cyber aggression within close relationships, and we hope that bullying prevention programs will incorporate these findings into their curricula, particularly through the development of interventions to help heal or resolve toxic, abusive relationships among teens,"" Felmlee said. In addition to potential efforts in schools to stop cyberbullying, Felmlee said parents can also take steps to mitigate cyber aggression in their children's lives. ""Many people may be unaware that current or former friends and romantic partners are the most likely perpetrators of cyberbullying, at least among school-aged teens,"" Felmlee said.","In analyses not shown here, we find that the rate per thousand of being attacked diminishes as the friendship distance between the aggressor and the victim widens. Time 2 cyber aggression is 4.3 times more likely to occur between Time 1 friends (or former friends) than between friends of friends. Approximately 17.2 percent of the student body in our sample was involved in cyber aggression in some way, with approximately 8.1 percent victimized by cyber aggression within a short timeframe.","[2.0, 2.0, 1.0, 3.0]",Psychology,train,2.0,news,http://www.science20.com/news_articles/former_friends_exdates_more_likely_to_turn_into_teen_cybertormentors-178916
10.1007/s13524-014-0321-x,Psychology_5,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births.",Significance markers under the x-axis are for the test between married and not married and are as follows: † p < .10; *p < .05; **p < .01; ***p < .001 Table 2 .,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births. The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.","The test for the difference between partnered and nonpartnered is significant at p < .001 (SOEP) and p < .05 (BHPS). Significance markers under the x-axis are for the test between married and not married and are as follows: † p < .10; *p < .05; **p < .01; ***p < .001 Table 2 . For second births, the overall trajectory is similar, but the increase in happiness before and around the birth is lower than for first births (p < .05).","[1.0, 1.0, 5.0, 1.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_50,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,", 44 This This study found that another brain region strongly associated with the effects of depressive problems on sleep quality is the precuneus.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","This helps to cross-validate the findings in the data sets from China in which all these areas have been identified in a network of brain areas with different functional connectivity in depression. , 44 This This study found that another brain region strongly associated with the effects of depressive problems on sleep quality is the precuneus. 40 On the bases of the findings of this study and others, 16, we propose that the low self-esteem in depression is associated with increased functional connectivity between the precuneus (which is involved in the representation of self) and the lateral orbitofrontal cortex, which is involved in nonreward and therefore implicated in depression.","[3.0, 5.0, 3.0, 2.0]",Psychology,train,3.25,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1073/pnas.1308718110,Psychology_500,"Just like humans, monkeys are able to select objectively better options from a menu of choices.","Notably, this shift to a risk-neutral or a risk-averse estimate closely paralleled the monkey's shift toward consistency as indexed by obeying first-order stochastic dominance (Fig.","""We found that after training, monkeys are very rational. Just like humans, monkeys are able to select objectively better options from a menu of choices. ""The monkeys also seem to share human risk preferences.","We found that monkeys were risk seeking early in training, but this risk-seeking behavior (α > 1) became risk neutral (α statistically indiscriminable from 1.0) and then slightly risk averse (α < 1) as the monkeys gained experience (Fig. Notably, this shift to a risk-neutral or a risk-averse estimate closely paralleled the monkey's shift toward consistency as indexed by obeying first-order stochastic dominance (Fig. This suggests that when choice behavior is technically inconsistent (and utility models assuming monotonicity should not be applied), behavior erroneously appears risk seeking, using such analyses.","[4.0, 2.0, 2.0, 2.0, 1.0]",Psychology,train,2.2,news,http://www.natureworldnews.com/articles/3979/20130914/monkeys-understand-basic-forms-wealth.htm
10.1177/2158244019828850,Psychology_501,"While drivers included an enjoyment of arguing, desire to affirm political beliefs, and hope to engage productively with those of opposing views, they also found some less-obvious results:

People are likely to engage with those who have different beliefs and backgrounds

While negative comments are more likely to spark sustained conversation, positive tweets are most likely to receive positive replies, suggesting that pleasant political conversations are possible

Individuals fall into engagement patterns - if they engage, they do so frequently and if they don't, they tend to remain disengaged

""Taken together, these findings suggest that average citizens are participating in rich and engaging political conversations,"" commented study authors Sarah Shugars and Nicholas Beauchamp.","Using data from Facebook and Wikipedia, find the identities of recent commenters is most predictive of conversation reentry.","While drivers included an enjoyment of arguing, desire to affirm political beliefs, and hope to engage productively with those of opposing views, they also found some less-obvious results:

People are likely to engage with those who have different beliefs and backgrounds

While negative comments are more likely to spark sustained conversation, positive tweets are most likely to receive positive replies, suggesting that pleasant political conversations are possible

Individuals fall into engagement patterns - if they engage, they do so frequently and if they don't, they tend to remain disengaged

""Taken together, these findings suggest that average citizens are participating in rich and engaging political conversations,"" commented study authors Sarah Shugars and Nicholas Beauchamp. The researchers propose broadly increasing conversational activity online and developing tools to make it easier to engage and follow long threads in order to extend and enrich these interactions. In addition, given users' willingness to respond to those unlike themselves, the researchers suggest that there is value in showing users new and different content, rather than recommendations based on the content with which they have already interacted.","Supporting this theory, find that the number of distinct users in long threads follows a bimodal distribution. Using data from Facebook and Wikipedia, find the identities of recent commenters is most predictive of conversation reentry. This lattermost line of work is largely a-theoretical and not particularly concerned with normative issues.","[4.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39221909866&p=1pl&v=1&x=whEjj0mJHbu-qETxEHKRdQ
10.1037/a0038032,Psychology_502,"That woman (or man) at the bar no longer looks so special, and the odds of you approaching him or her, and possibly making a bad decision regarding who to become intimate with, are dramatically decreased.","Examining attractiveness ratings of healthy and unhealthy foods as a function of participants' hunger scores and training condition revealed that, analogous to food choices, hunger affected the preferences for unhealthy and healthy food differently across training groups.","But if you've gotten in a detached state of mind, and are able to consciously notice that impulse arise, the magic deflates. That woman (or man) at the bar no longer looks so special, and the odds of you approaching him or her, and possibly making a bad decision regarding who to become intimate with, are dramatically decreased. In all these cases, ""when participants were instructed and trained to see that their experiences were mere thoughts, constructed by their own minds, the stimuli themselves became less attractive, and resisting them became easier,"" the researchers conclude.","Although no response window was used, participants' mean choice responses were relatively fast (M ϭ 878 ms, SD ϭ 277), suggesting that they followed our instructions to indicate their momentary wanting spontaneously. Examining attractiveness ratings of healthy and unhealthy foods as a function of participants' hunger scores and training condition revealed that, analogous to food choices, hunger affected the preferences for unhealthy and healthy food differently across training groups. Hunger slightly increased the attractiveness of unhealthy foods among control participants, ␤ ϭ .29, t(37) ϭ 1.80, p ϭ .077, but not among mindful attention participants, ␤ ϭ Ϫ.04, t(34) ϭ Ϫ0.23, p ϭ .82, who rated the unhealthy foods as less attractive overall, ␤ ϭ .28, t(72) ϭ 2.47, p ϭ .02.","[1.0, 2.0, 1.0, 1.0]",Psychology,train,1.25,news,http://www.psmag.com/navigation/health-and-behavior/mindfulness-training-twelve-minutes-avoiding-temptation-94637/
10.1111/nyas.12179,Psychology_503,"While it's true that people are generally averse to harming others, the bottom line is that people don't feel this way all the time.""","c, 26 When the out-group or one of its members suffers a misfortune, this sense of inferiority-and we argue, resulting envious prejudice-leads to intergroup schadenfreude.","""We found that surprising because we weren't certain participants would self report that. While it's true that people are generally averse to harming others, the bottom line is that people don't feel this way all the time."" Again, the findings matched earlier experiments -- participants rated the articles associated with disgust and envy with less warmth than the pride or pity scenarios.","50 can make salient one's own group's relative inferiority, generating hostile, group-based envy. c, 26 When the out-group or one of its members suffers a misfortune, this sense of inferiority-and we argue, resulting envious prejudice-leads to intergroup schadenfreude. People generally prefer their own in-group to outgroups, 30 but not all out-groups are equivalent.","[1.0, 4.0, 4.0, 3.0]",Psychology,train,4.0,news,http://www.sciencedaily.com/releases/2013/10/131028101117.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1002/hbm.22842,Psychology_504,"The researchers stated that the process was, in effect, able to read the minds of the participants while they contemplated a brand-new thought.","It may soon become possible to measure activation-related changes in knowledge representation simultaneously with gray and white matter changes, in conjunction with various types of knowledge acquisition.","They are also meaningful and can be interpreted. The researchers stated that the process was, in effect, able to read the minds of the participants while they contemplated a brand-new thought. The result of the experiment also revealed that once an animal's property was learned, the information remains intact in the brain regardless whether other properties of the animal are learned.","The new results here complement this body of research by documenting a change in brain function (activation patterns) accompanying the emergence of new conceptual knowledge, versus the enhancement of an intellectual skill (reading) or motor skill (juggling). It may soon become possible to measure activation-related changes in knowledge representation simultaneously with gray and white matter changes, in conjunction with various types of knowledge acquisition. The findings of the current study may foreshadow a capability to apply brain imaging and multivoxel pattern analyses to assess the progress in learning a complicated concept-such as that of a high-school physics lesson-by monitoring the changes in the concept's neural representation as new features or aspects of the concept are learned.","[3.0, 1.0, 3.0, 4.0]",Psychology,train,2.75,news,http://www.techtimes.com/articles/59701/20150612/heres-how-newly-learned-concepts-form-in-your-brains-filing-system.htm
10.1098/rspb.2017.2171,Psychology_505,"The findings suggest that a captive whale's ability to deftly mimic unfamiliar noises hints that imitation likely plays an important role in building orcas' unique ""vocal traditions.""","Additionally, our nondifferential reinforcement regime (good copies of novel sounds were not reinforced to avoid shaping) may have also contributed to this variability.","And she reproduced the new sounds quickly, some within the first attempt. The findings suggest that a captive whale's ability to deftly mimic unfamiliar noises hints that imitation likely plays an important role in building orcas' unique ""vocal traditions."" The researchers found that Wikie successfully copied all of the sounds, most of them in fewer than 10 tries.","Possible factors that could explain this variability are the difficulty in producing novel sounds and some uncontrolled factors such as variation in motivational levels across sessions. Additionally, our nondifferential reinforcement regime (good copies of novel sounds were not reinforced to avoid shaping) may have also contributed to this variability. Consequently, it is conceivable that our data represent a conservative estimate of the killer whale's capacity for vocal imitation.","[2.0, 3.0, 1.0, 3.0, 3.0]",Psychology,train,2.4,news,http://ct.moreover.com/?a=33157263707&p=1pl&v=1&x=BGfE7xuV4FecUerpZhJU8A
10.1016/j.jenvp.2019.04.012,Psychology_506,"The team's online modules avoid confrontational approaches ""which threaten preexisting beliefs and convictions,"" suggesting a relatively simple guide for how to overcome skepticism about GM foods: focus on the actual underlying science not the message.","Subjects were primarily white (78%); 33% had a bachelor's degree, 27% had some college, 20% had an advanced degree, and 11% had a high school education or less.","Their findings, argues the team, lend direct support for the deficit model of science attitudes, which--in broad terms--holds that the public's skepticism towards science and technology is largely due to a lack of understanding, or absence of pertinent information. The team's online modules avoid confrontational approaches ""which threaten preexisting beliefs and convictions,"" suggesting a relatively simple guide for how to overcome skepticism about GM foods: focus on the actual underlying science not the message. For McPhetres, the studies tie neatly into his larger research focus on people's basic science knowledge and general interest in science--and how to improve both.","Subjects were 362 adults (142 female) with an average age of 33.53 years (SD = 10.88). Subjects were primarily white (78%); 33% had a bachelor's degree, 27% had some college, 20% had an advanced degree, and 11% had a high school education or less. Fiftyfour subjects were excluded for failing at least one attention check or for not completing the main measures, resulting in a final sample of n = 309.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39339658521&p=1pl&v=1&x=OpPfTQoRjtinRFtRfzn_CA
10.1073/pnas.1809779115,Psychology_507,"Rather, producing both at the same time was easier than having to suppress the dominant language (in this case English) in order to name the picture on the screen only in ASL.","Additionally, by comparing the production of a single language (ASL or English) to the simultaneous production of both languages, we found that activity associated with lexical retrieval increased during simultaneous production of ASL and English compared with only producing English (our participants' dominant language), but neural activity decreased compared with producing only ASL (the nondominant language) while inhibiting English.","In fact, they also found that for such speakers, producing two words simultaneously (one sign and one spoken word) was not necessarily more cognitively costly than producing only one. Rather, producing both at the same time was easier than having to suppress the dominant language (in this case English) in order to name the picture on the screen only in ASL. ""In all, these results suggest that the burden of language-switching lies in disengagement from the previous language as opposed to engaging a new language,"" says Blanco-Elorrieta.","Our results revealed that, in language switching, disengagement (turning off a language) elicits increased activity in the dlPFC and ACC, but engaging in a new language (turning on a language) does not incur a neural switch cost. Additionally, by comparing the production of a single language (ASL or English) to the simultaneous production of both languages, we found that activity associated with lexical retrieval increased during simultaneous production of ASL and English compared with only producing English (our participants' dominant language), but neural activity decreased compared with producing only ASL (the nondominant language) while inhibiting English. These results suggest that dual lexical retrieval does not necessarily incur any additional neural cost; on the contrary, neural activity during lexical retrieval of the nondominant language (ASL) is reduced by simultaneous production of English, a result that is consistent with behavioral data from ref.","[4.0, 5.0, 3.0, 5.0, 4.0]",Psychology,train,4.2,news,http://ct.moreover.com/?a=37063035417&p=1pl&v=1&x=wnsqYzyklRJfO8xg5aA7qw
10.1001/jamapsychiatry.2015.0469,Psychology_508,These results are important for clinicians since children who display increased symptoms over time (a decline being normative in the population) might represent a marker of genetic vulnerability and warrant closer follow-up.,The results presented in eTable 5 are presented for descriptive purposes and caution should be applied when interpreting them.,Therefore this proposes that different sets of genes may be associated with the developmental course versus the baseline level of symptoms and may explain why some children remit and others persist. These results are important for clinicians since children who display increased symptoms over time (a decline being normative in the population) might represent a marker of genetic vulnerability and warrant closer follow-up. It is associated with a 3-5 times increase in risk of stroke.,"Finally, the score on the Conners inattention scale rated by teachers at age 14 years was higher for children with increasing inattention. The results presented in eTable 5 are presented for descriptive purposes and caution should be applied when interpreting them. Consequently, separating the sample into two sub-groups following different developmental trajectories based on the slope value is arbitrary as it cuts in a continuous distribution (here below and above 0).","[1.0, 1.0, 3.0, 1.0]",Psychology,train,1.5,news,http://www.2minutemedicine.com/2-minute-medicine-rewind-may-3-may-10-2015/
10.1016/j.cognition.2014.01.002,Psychology_509,"Here, repeatedly getting the same outcome decreases the probability of that outcome occurring in the future.",People who won were more likely to win again (apparently because they chose safer odds than before) whereas those who lost were more likely to lose again (apparently because they chose riskier odds than before).,"The gambler's fallacy works in the opposite direction. Here, repeatedly getting the same outcome decreases the probability of that outcome occurring in the future. A roulette ball landing on red after one spin has zero effect on what happens on the next spin.","People suffering from the hot-hand fallacy unreasonably expect winning streaks to continue whereas those suffering from the gamblers' fallacy unreasonably expect losing streaks to reverse. People who won were more likely to win again (apparently because they chose safer odds than before) whereas those who lost were more likely to lose again (apparently because they chose riskier odds than before). However, selection of safer odds after winning and riskier ones after losing indicates that online sports gamblers expected their luck to reverse: they suffered from the gamblers' fallacy.","[4.0, 3.0, 3.0]",Psychology,train,3.333333333333333,news,http://www.businessinsider.com/the-gamblers-fallacy-and-the-hot-hand-2014-4
10.1016/j.jpeds.2017.10.028,Psychology_51,"Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence.","There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","There was a positive relationship between corporal punishment and physical violence during a romantic relationship. Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence. These results remained even when the team accounted for the number of children who experienced child abuse, which is described as any form of punishment that is inappropriate or causes series injury.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[1.0, 2.0, 2.0]",Psychology,train,1.6666666666666667,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1111/desc.12078,Psychology_511,"Most of the remaining children fell into groups that knew only the number one, the numbers one and two, the numbers one through three, and a few that knew one through four -- the same breakdown seen in children in industrialized countries.",suggests that it is critically important that children learn to recite the list of number words in order before making the CP-transition.,"Although the Tsimane' live in a fairly remote area, they do have some contact with Spanish speakers living nearby. Most of the remaining children fell into groups that knew only the number one, the numbers one and two, the numbers one through three, and a few that knew one through four -- the same breakdown seen in children in industrialized countries. advertisement

The results suggest that those counting stages are universal in child development, the researchers say.","This view that the stages of knowledge are driven by the learner's core representational system accords with our finding of similar stages in a substantially distinct culture. suggests that it is critically important that children learn to recite the list of number words in order before making the CP-transition. She argues that this list provides a placeholder structure that provides a framework for the CP-induction-moving ""one more"" in terms of cardinality equates to one further item on the memorized list of words.","[4.0, 3.0, 3.0, 1.0]",Psychology,train,2.75,news,http://www.sciencedaily.com/releases/2014/06/140618132009.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1073/pnas.1421304111,Psychology_512,"The findings from this work support the general premise of the hypothesis, but suggest that other factors such as noradrenaline are also crucial.""",An intriguing question raised by these results is how β-AR activation in the LA modulates Hebbian processes and synaptic plasticity in this small cell population to produce threat learning.,"According to Johansen, ""This work represents one of the first tests of an influential hypothesis for memory formation in the working brain. The findings from this work support the general premise of the hypothesis, but suggest that other factors such as noradrenaline are also crucial."" The study provides a new perspective on how aversive experiences, such as being attacked by a dog, for example, are translated by the brain into emotional fear memories and may represent a general process to control memory formation in other brain areas.","Thus, other factors such as the availability or levels of intracellular signaling molecules, local competition between cell assemblies, or the availability of auditory CS inputs to a given cell may have played a role in allocation of plasticity to a small proportion of the stimulated neurons ( . An intriguing question raised by these results is how β-AR activation in the LA modulates Hebbian processes and synaptic plasticity in this small cell population to produce threat learning. However, in addition to being expressed in glutamatergic neurons in LA, β-ARs are also expressed in presynaptic inputs to these neurons and in GABAergic and astrocytic cells .","[2.0, 2.0, 3.0, 2.0]",Psychology,train,2.25,news,http://www.sciencedaily.com/releases/2014/12/141208152514.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1177/1745691611400234,Psychology_513,"Because we describe the effects of emotion using mathematical equations, our work may allow scientists, one day, to predict what experiences an individual will recall.",detected one emotional face in an array of neutral faces found that computationally modeled bottom-up visual saliency (using the model shown in Fig.,"Those small changes lead to important, holistic effects on the entire process of memorising. Because we describe the effects of emotion using mathematical equations, our work may allow scientists, one day, to predict what experiences an individual will recall. ADVERTISEMENT

But once we gather more data on these intermediate steps, our model's predictions may more accurately reproduce the recall pattern of individuals.","Viewing emotional stimuli also increases activity in visual brain areas associated with object recognition, such as the fusiform and inferotemporal cortices , and it leads to an early posterior negativity in eventrelated brain potential studies detected one emotional face in an array of neutral faces found that computationally modeled bottom-up visual saliency (using the model shown in Fig. When participants looking at a neutral face thought they saw an emotional face, activity in posterior visual regions showed the same type of enhanced activity seen during actual emotional face perception.","[2.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.6,news,http://ct.moreover.com/?a=39620813686&p=1pl&v=1&x=XYFyiRudO0tWZNwrp7yLMA
10.1111/irel.12214,Psychology_514,I was blindly aiming high when I should have been aiming strategically.,I have asked for pay raise is a dummy for having requested a greater salary during this job tenure with the current employer.,"My friend's advice wasn't bad, but I actually had no idea whether I was undervaluing myself. I was blindly aiming high when I should have been aiming strategically. To be clear: Negotiating is a good thing.","The variable pay is negotiated is a dummy for whether the employee says that pay levels are fixed by negotiation with the employer (this is not, it should perhaps be emphasized, a measure of ""asking""). I have asked for pay raise is a dummy for having requested a greater salary during this job tenure with the current employer. Satisfied with wage is a dummy for reporting that I am satisfied with my income in the job with the current employer.","[5.0, 1.0, 2.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=39545697853&p=1pl&v=1&x=rdWUnAAciB-xerCilFZmjg
10.1111/cdev.12889,Psychology_515,"The changes in sleep and cortisol were largest when the crime committed the previous day was homicide, they were moderate for assault and sexual assault and nonexistent for robbery.",Effects for robbery were never statistically significant.,"In addition, the increase in youth's cortisol levels the morning after a nearby crime occurred the day before was larger than on mornings following no crime the previous day, a pattern that previous research suggests might reflect the body's anticipation of more stress the day following a crime. The changes in sleep and cortisol were largest when the crime committed the previous day was homicide, they were moderate for assault and sexual assault and nonexistent for robbery. ""The results of our research have several implications for policy,"" suggested study co-author Emma Adam, professor of human development and social policy at SESP.","Criminal sexual assault was associated with a .18 lg/dl increase in cortisol on the night of the crime (p = .012). Effects for robbery were never statistically significant. Removing robbery from the Panel A estimate resulted in a larger coefficient for the effect on CAR (estimated at .22 lg/dl, p = .003).","[2.0, 1.0, 4.0, 5.0, 3.0]",Psychology,train,2.0,news,http://healthmedicinet.com/news/study-explains-link-between-academic-performance-and-violence/
10.1177/0261927x99018001002,Psychology_516,It's shocking to think of how many people might be wrongfully punished simply because they use a dialect that's different to what's considered standard.,"Second, it also illustrates how little speech is needed for dialect identification.","And in moments of intense emotion a such as an interrogation a anyoneas ability to code-switch can be impacted. It's shocking to think of how many people might be wrongfully punished simply because they use a dialect that's different to what's considered standard. When neither court recorders, jurors, lawyers, or judges possess a grasp of this valid form of language, it can lead to injustices that take years to correct a if they ever are meaningfully addressed.","This allowed us to hold external factors to a minimum. Second, it also illustrates how little speech is needed for dialect identification. ""Hello"" is a self-contained utterance, making perceptual studies more natural.","[1.0, 2.0, 4.0, 2.0, 2.0]",Psychology,train,2.2,news,http://ct.moreover.com/?a=39446591773&p=1pl&v=1&x=KytwFFEryFNERe0-ep9NBg
10.1038/nn.4071,Psychology_517,"""The results revealed a delicate coordination in the brain's code,"" Voytek says.","We also observed a task-by-region interaction (F 6,1644 = 3.04, P = 0.0058) such that encoding-triggered PAC increased as a function of task differentially depending on the location of the encoding pair.","[related]

As the tasks became more demanding, the oscillations kept up, coordinating more parts of the frontal lobe and synchronizing the information passing between those brain regions. ""The results revealed a delicate coordination in the brain's code,"" Voytek says. ""Our neural orchestra may need no conductor, just brain waves sweeping through to briefly excite neurons, like millions of fans in a stadium doing 'The Wave.'""","Theta/high gamma PAC increased with task demands such that the theta phase in an electrode provided task-dependent information about the gamma amplitude around the theta phase-encoding time (main effect of task abstraction, F 3,1644 = 31.29, P < 10 −18 ; Fig. We also observed a task-by-region interaction (F 6,1644 = 3.04, P = 0.0058) such that encoding-triggered PAC increased as a function of task differentially depending on the location of the encoding pair. More specifically, encoding-triggered PAC increases as a function of task between encoding PFC electrode pairs (F 3,954 = 88.55, P < 10 −49 ) and for encoding pairs between M1/PMC and PFC (F 3,597 = 30.75, P < 10 −17 ), but less so for encoding pairs in M1/PMC (F 3,93 = 2.29, P = 0.084).","[3.0, 3.0, 1.0]",Psychology,train,2.333333333333333,news,http://www.futurity.org/brain-waves-jazz-968642/
10.1098/rspb.2014.0218,Psychology_518,"Thus, Lopes argues, sickness behaviors would impact survival positively -- but only to a certain extent.","These differences might suggest that while females of species with biparental care can afford to invest in reproduction while sick, given the paternal contribution to care, the opposite behaviour might be adaptive for females that receive no help from males in caring for offspring.","These behaviors are not often caused by the infection itself, but rather by the immune system's response to it. Thus, Lopes argues, sickness behaviors would impact survival positively -- but only to a certain extent. Likewise, if more time and energy is invested into feeling sick, reproduction would decrease.","For example, while IL-1b administration to females of a uniparental (female-only) rodent species (Mus musculus) inhibited sexual behaviour and eliminated the expected preference to mate with intact versus castrated males , LPS injection of females of a biparental rodent species (Microtus ochrogaster) enhanced partner preference of familiar versus unfamiliar males and facilitated pair bonding . These differences might suggest that while females of species with biparental care can afford to invest in reproduction while sick, given the paternal contribution to care, the opposite behaviour might be adaptive for females that receive no help from males in caring for offspring. Indeed, male house sparrows show increased paternal effort (feeding rate) when their mates reduce feeding effort owing to an LPS injection .","[5.0, 2.0, 2.0, 1.0, 4.0]",Psychology,train,2.0,news,http://www.medicaldaily.com/fake-it-till-you-make-it-difference-between-being-sick-and-acting-sick-depends-your-environment
10.1016/j.nicl.2014.01.001,Psychology_519,"It found that those who experienced mild to moderate family difficulties between birth and 11 years of age had developed a smaller cerebellum, an area of the brain associated with skill learning, stress regulation and sensory-motor control.",Other limitations include the use of reliance of information obtained from maternal interview using the CAMEEI and the relatively high SES background of participants in this study that may contrast with the SES of participants in other studies who may have experienced more severe forms of abuse and adversity.,"It found that those who experienced mild to moderate family difficulties between birth and 11 years of age had developed a smaller cerebellum, an area of the brain associated with skill learning, stress regulation and sensory-motor control. The researchers also suggest that a smaller cerebellum may be a risk indicator of psychiatric disease later in life, as it is consistently found to be smaller in virtually all psychiatric illnesses. Dr Walsh, from UEA's School of Psychology, said: ""These findings are important because exposure to adversities in childhood and adolescence is the biggest risk factor for later psychiatric disease.",It would therefore also be advantageous in future studies to have repeated neuroimaging scans to dynamically understand the moderating effects of environmental variables over the life course. Other limitations include the use of reliance of information obtained from maternal interview using the CAMEEI and the relatively high SES background of participants in this study that may contrast with the SES of participants in other studies who may have experienced more severe forms of abuse and adversity. The findings show that moderate and chronic childhood adversities characterized by inter-parental discord are associated with widespread changes in GMV in the late adolescent brain.,"[2.0, 2.0, 2.0, 2.0]",Psychology,train,2.0,news,http://www.technology.org/2014/02/20/family-problems-experienced-childhood-adolescence-affect-brain-development/
10.1073/pnas.1303547110,Psychology_521,"While the results show that a pointer-like system could be at play in the brain, the function is not identical to the system used in computer science, the scientists said.",The PBWM maintenance-only network performed well on the standard generalization task.,"After the training period, the researchers fed the model new sentences using familiar words in novel ways and found that the model could still comprehend the sentence structure. While the results show that a pointer-like system could be at play in the brain, the function is not identical to the system used in computer science, the scientists said. It's similar to comparing an airplane's wing and a bird's wing, O'Reilly said.","Based on prior models, it may require training on a larger portion of all possible sentences (23-25). The PBWM maintenance-only network performed well on the standard generalization task. This is because it was able to store each word as the filler of the appropriate role in dedicated, independently updatable PFC stripes for each role.","[1.0, 2.0, 1.0, 1.0, 1.0]",Psychology,train,1.2,news,http://www.healthcanal.com/brain-nerves/43209-brain-may-rely-on-computer-like-mechanism-to-make-sense-of-novel-situations-says-cu-boulder-study.html
10.1016/j.bbr.2015.10.056,Psychology_522,What does this finding mean?,"In the current study, testosterone administration was found to increase MTL activity related to successful navigation, but did not affect behavioral measures of navigation success even though MRT performance was significantly improved.","What does this finding mean? It simply means that Dr. Carl W.S. Pintzka's team of researchers proved that there really is a connection between hormone levels and navigation skills because they found that men used their hippocampus more during way finding tasks, unlike women whose brains were wired to use the frontal cortex.","The resting state fMRI analysis did not reveal any statistical significant differences between the two drug groups. In the current study, testosterone administration was found to increase MTL activity related to successful navigation, but did not affect behavioral measures of navigation success even though MRT performance was significantly improved. The results point to increased testosterone levels having a limited effect on spatial cognition, pertaining specifically to performance on tasks probing 3D representations of space, since the testosterone group also performed notably better on the VE direction task.","[1.0, 4.0, 1.0, 5.0]",Psychology,train,1.0,news,http://www.techtimes.com/articles/114219/20151208/study-says-men-have-better-sense-of-direction-than-women.htm
10.1001/jamapsychiatry.2017.4363,Psychology_523,"La urma urmei, in cazul meu au fost alti factori in joc: o relatie dificila cu tatal meu, probleme financiare.","Of the 8287 children, 4227 (51%) were boys and 4060 (49%) were girls.","E imposibil sa-mi dau seama daca experienta ei are vreo legatura cu propria mea depresie postnatala. La urma urmei, in cazul meu au fost alti factori in joc: o relatie dificila cu tatal meu, probleme financiare. Totusi, studiile arata ca un copil care are un parinte depresiv va suferi si el de depresie mai tarziu.","For the 9848 mothers in the sample, the mean (SD) age at delivery was 28.5 (4.7) years. Of the 8287 children, 4227 (51%) were boys and 4060 (49%) were girls. Compared with women with PND that was not persistent and women who did not score above the EPDS threshold, for all 3 severity levels, women with persistent PND showed elevated depressive symptoms up to 11 years after childbirth.","[1.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.4,news,http://ct.moreover.com/?a=33561133478&p=1pl&v=1&x=EsgUSeRV5Uj9yhGXcVKZfg
10.1016/j.jesp.2018.07.004,Psychology_524,You are quite dateable!,"In this way, the consequentialist action in our impartiality dilemmas we used in this study -and especially the spending money variant -directly match onto the action that we should do on effective altruism principles.","But fear not good people, nice folks, and consequentialists among you. You are quite dateable! Because even though you might make the hard call if presented with one in the vacuum of philosophy class, video game, or episode of Star Trek, chances are that in everyday life you still make decisions that prioritize your family and friends.","Finally, our work has practical implications concerning how in everyday life groups and individuals who advocate a more impartial, welfare-maximising consequentialist approach to moral decisionssuch as the ""effective altruism"" movement -might expect to be perceived, and how this might limit their advocacy. In this way, the consequentialist action in our impartiality dilemmas we used in this study -and especially the spending money variant -directly match onto the action that we should do on effective altruism principles. Our work suggests that effective altruists may face stumbling blocks in how they are perceived by others and that, while receiving far less criticism than consequentialists can receive for endorsing instrumental harm, this may still have harmful consequences for how the movement is perceived and therefore, presumably, how many people join the movement and adopt its principles.","[1.0, 2.0, 1.0, 2.0, 1.0]",Psychology,train,1.4,news,http://ct.moreover.com/?a=40056086702&p=1pl&v=1&x=9jAXFGc_3paVqmHCoy0ldQ
10.1007/s12369-014-0253-z,Psychology_525,"Professionals plotting revolution

But the job apocalypse might have a silver lining.","Damasio and Carvalho state that a lack of homeostasis in the body will trigger adaptive behavior via brain networks, such as attention to a stranger's next move.","Bill Gates seems to think the crisis is self-evident, saying he doesn't ""understand why some people are not concerned."" Professionals plotting revolution

But the job apocalypse might have a silver lining. They were not well-organized.","Therefore, in the conceptual model in Fig. Damasio and Carvalho state that a lack of homeostasis in the body will trigger adaptive behavior via brain networks, such as attention to a stranger's next move. This implies that a homeostasis-like structure is needed to design embodied emotional representations.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.realclearscience.com/articles/2017/11/02/will_robot_workers_spark_a_human_revolt_110439.html
10.1353/dem.0.0053,Psychology_526,Performing even worse were those who were so-called mixed-handed.,(Note that we already control for birth weight and whether the child was in intensive care when born.),"The Trials of Being Left-Handed

While it's easy to believe that lefties will one day get over these everyday physical problems -- and many do to some extent -- being a lefty may have far deeper issues. Performing even worse were those who were so-called mixed-handed. And maybe, all of these are all just a result of the stigma we put behind being a lefty.","Although most of the evidence concerns adults, if any health differences already exist by childhood, this might partially explain the differences in development by handedness. (Note that we already control for birth weight and whether the child was in intensive care when born.) Our results are robust to these changes.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.medicaldaily.com/left-handed-people-have-ups-and-downs-and-sometimes-rights-possible-dangers-being-lefty-272540
10.1111/jsr.12712,Psychology_527,But individuals who balanced their short weekday sleep with longer weekend sleep did not appear to have any increased mortality risk.,This should have led to the interpretation of the second question as referring to weekend by those not working.,"The researchers found that people ages 65 and under who slept 5 hours or less a night had a 65 percent higher risk of death during the 13-year study period than those who got 6 or 7 hours of sleep a night. But individuals who balanced their short weekday sleep with longer weekend sleep did not appear to have any increased mortality risk. The findings suggest, in other words, that you may be able to make up for the damaging effects of lost sleep.","The strengths of our study include its large size, its prospective design, the length and the completeness of the follow-up, ascertained through linkages to nationwide registers, the high quality of the baseline data guaranteed by a low level of missing values, and the availability of two separate questions investigating sleep habits during weekdays and weekends/days off. This should have led to the interpretation of the second question as referring to weekend by those not working. Another limitation is that sleep duration was self-reported and assessed only at baseline; therefore, it is not possible to detect changes in sleep habits over time among the subjects included in the T A B L E 2 Quantile regression analysis for percentile differences (PD) in months in age at death across levels of weekday/weekend sleep duration groups in the Swedish National March Cohort Estimates were obtained by fitting a Laplace regression on the 25th, 50th and 75th percentiles of age at death adjusted for age at baseline.","[2.0, 2.0, 2.0, 1.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=34124787497&p=1pl&v=1&x=F4q7Gy6HLapm-GNj0yd2dQ
10.1016/j.neuron.2006.11.010,Psychology_528,This glut of clothing is having effects beyond stuffing our closets.,Conjointly activated regions passing this threshold thus identified replicable activations over both product sets at p < 0.001 .,"In 2013, it was up to 63.7 garments, down from a peak of 69 just before the recession. The consumption isn't by any means limited to the U.S. Women in Britain, for instance, now own four times as much clothing as they did in 1980. This glut of clothing is having effects beyond stuffing our closets.","Thus, positive price differential indicated that subjects perceived a product as cheap (relative to their willingness to pay for it), while negative price differential indicated that subjects perceived a product as expensive (i.e., similar to ''net utility'' or ''consumer surplus'' in economics) . Conjointly activated regions passing this threshold thus identified replicable activations over both product sets at p < 0.001 . Logistic regression models also included fixed effects and motion correction estimates ) (however, analyses remained significant and qualitatively similar when fixed effects were not included in the models).","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.theatlantic.com/entertainment/archive/2015/03/the-neurological-pleasures-of-modern-shopping/388577/
10.1002/hbm.23803,Psychology_529,"""Good roads make for efficient travel, and the brain is no different.","Consistent with this prediction, Figure 8 clearly shows that WMD in a number of ROIs near the stimulated left MFG region were enhanced by 5 Hz rTMS, including the stimulation site (5 Hz: t 13 5 3.45, P < 0.005; 1 Hz: t 13 5 0.32, P 5 n.s.).","Furthermore, when the authors examined the white matter pathways between these bilateral regions, participants with stronger white matter fibers connecting left and right hemispheres demonstrated greater bilateral communication, strong evidence that structural neuroplasticity keeps the brain working efficiently in later life. ""Good roads make for efficient travel, and the brain is no different. By taking advantage of available pathways, aging brains may find an alternate route to complete the neural computations necessary for functioning,"" said Davis.","No such relationships were observed in the relationship between univariate activity and WMD at the stimulation site (all r < 0.05), nor did whole-brain distributions show differences between stimulation conditions. Consistent with this prediction, Figure 8 clearly shows that WMD in a number of ROIs near the stimulated left MFG region were enhanced by 5 Hz rTMS, including the stimulation site (5 Hz: t 13 5 3.45, P < 0.005; 1 Hz: t 13 5 0.32, P 5 n.s.). Additionally, 5 Hz rTMS also increased memory- BMD associated with SME across rTMS conditions.","[1.0, 1.0, 3.0, 1.0, 3.0]",Psychology,train,1.8,news,http://healthmedicinet.com/news/brain-halves-increase-communication-to-compensate-for-aging-study-finds/
10.1016/j.jpeds.2017.10.028,Psychology_53,About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood.,"Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498).","""While we can't say that spanking causes later violence, it follows that if a kid learns that physical punishment is a way to solve conflict, he/she may carry that over into conflicts with later intimate partners,"" said study senior author Jeff Temple. About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","[2.0, 5.0, 4.0, 2.0]",Psychology,train,5.0,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1038/mp.2015.69,Psychology_530,"The results provide the most comprehensive look at the effects of long-term solitary confinement yet, according to the Times.",We also found that Figure 2 .,"The results provide the most comprehensive look at the effects of long-term solitary confinement yet, according to the Times. In such extreme isolation for years, the prisoners Haney interviewed at Pelican Bay experienced what he calls a ""social death."" ""Most of them really did understand that they had lost who they were, and weren't sure of who they had become.""",We only observed hippocampal volume deficits in recurrent MDD and not in first episode patients. We also found that Figure 2 . (b) Cohen's d-effect sizes 95% CI for differences in subcortical brain volumes between early onset (⩽) MDD patients and healthy control subjects (no pattern) and between later onset (>) MDD patients and healthy controls (striped pattern).,"[1.0, 2.0, 1.0, 1.0, 1.0]",Psychology,train,1.2,news,http://www.businessinsider.com/solitary-confinement-causes-social-death-2015-8
10.1038/nn.3303,Psychology_533,These differences were also associated with a reduction of grey matter in a part of the brain called the medial prefrontal cortex.,"When recognition based on recollection and on familiarity were summed, no sleep-wake .","The extent of deep-sleep disruption was related to the degree of memory impairment, with those exhibiting the least slow-wave activity performing the worst. These differences were also associated with a reduction of grey matter in a part of the brain called the medial prefrontal cortex. ""Our findings show that brain deterioration, bad memory and bad sleep are not independent, but instead are significantly interrelated.""","They found a sleep-dependent benefit for gist words based on recollection memory, but reduced memory based on familiarity. When recognition based on recollection and on familiarity were summed, no sleep-wake . Similarly, probabilistic category learning, studied in the weather prediction task (right), shows significant improvement after a night of sleep, and significantly more than after an equal period awake during daytime, when no significant improvement was seen.","[1.0, 3.0, 5.0, 1.0, 3.0]",Psychology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=why-poor-sleep-and-forgetfulness-plague-the-aging-brain
10.1177/0022146516647098,Psychology_534,"By contrast, when the black working-class man made the same request to 80 therapists, only one therapist was willing or able to fulfill the request.","However, questions of bias in diagnosis and patient management are secondary to questions of access because the former presuppose a clinical encounter that only a subset of disadvantaged help seekers will obtain if there exists systematic bias in access.","Kugelmass also found that the white middle-class woman was favored for the coveted weekday evening appointment; she received an affirmative response to a request for an appointment in that time slot from 16 of 80 therapists (20 percent). By contrast, when the black working-class man made the same request to 80 therapists, only one therapist was willing or able to fulfill the request. ""Psychotherapists are not immune to the stereotypes that influence the decisions of other professionals,"" Kugelmass said.","1 These findings point toward the existence of provider-generated obstacles to access. However, questions of bias in diagnosis and patient management are secondary to questions of access because the former presuppose a clinical encounter that only a subset of disadvantaged help seekers will obtain if there exists systematic bias in access. I posit that racial and class bias influence decision making at the pre-encounter stage-namely, at the first request for care.","[3.0, 5.0, 3.0, 4.0]",Psychology,train,3.75,news,http://healthmedicinet.com/news/study-uncovers-racial-working-class-discrimination-in-private-mental-health-care-market/
10.1073/pnas.1613117114,Psychology_535,"Postdoctoral offices, departments, and administrators, the article's authors recommend, ""should incorporate explicit attention to issues of science identity in professional development programming for postdocs"" and educate faculty mentors about the importance of guiding postdocs toward building strong and resilient conceptions of themselves as scientists.","these results suggest that greater belonging and self-efficacy may serve as underlying psychological processes that explain why female peer mentors, who are slightly more advanced in college, would promote engineering career aspirations among women who are new to engineering.","Cultivating a science identity that admits such considerations appears likely to help postdocs move toward nonacademic careers with more confidence and self-regard. Postdoctoral offices, departments, and administrators, the article's authors recommend, ""should incorporate explicit attention to issues of science identity in professional development programming for postdocs"" and educate faculty mentors about the importance of guiding postdocs toward building strong and resilient conceptions of themselves as scientists. There's a message in this for postdocs, too, and even for graduate students: Take note of your developing conception of yourself as a scientist, and especially of any assumptions--even unconscious--about the nature of ""legitimate"" scientific work that might needlessly constrain your choices or limit options.","Taken together, Deviations from zero show a relative increase or decrease from time 1. these results suggest that greater belonging and self-efficacy may serve as underlying psychological processes that explain why female peer mentors, who are slightly more advanced in college, would promote engineering career aspirations among women who are new to engineering. The results are promising but preliminary because of the smaller sample size.","[2.0, 1.0, 3.0, 2.0, 4.0]",Psychology,train,2.4,news,http://ct.moreover.com/?a=37015395056&p=1pl&v=1&x=MyAAPU-jI92IvGTKJ2Tsyg
10.1037/a0026545,Psychology_536,"To be sure, not every bad habit will disappear when you restructure your environment.","Our findings suggest that desire is a common, recurrent theme in daily life.","As soon as they got into the habit of, say, only eating vegan food or never eating food out of a box, it didn't take much for them to stay on track. To be sure, not every bad habit will disappear when you restructure your environment. If you're a cigarette smoker, staying out of bars might help, but it probably won't solve the problem immediately.","To our knowledge, this investigation is the first systematic attempt to provide empirical evidence about such basic questions as the prevalence of desire and conflict in everyday life and the frequency and effectiveness of self-control efforts to resist desire. Our findings suggest that desire is a common, recurrent theme in daily life. Frequent inner struggle to manage desire is another theme.","[2.0, 1.0, 1.0, 1.0, 2.0]",Psychology,train,1.4,news,http://ct.moreover.com/?a=37659559800&p=1pl&v=1&x=Kp1KW1j7IQi73IrzrBKmuQ
10.1093/emph/eou021,Psychology_539,"""It is telling that even in modern large-scale societies the status comparisons most consequential for psychosocial stress are typically among individuals who are in close geographic proximity or who occupy the same social network rather than between individuals at opposite ends of the socioeconomic spectrum.",Our confidence in the validity of the influence measure is strengthened by ethnographic observation.,"""Small-scale societies like the Tsimane shed light on our evolutionary history, during which we lived in groups much more egalitarian than the hereditary inequality and social stratification of recent human history,"" he said. ""It is telling that even in modern large-scale societies the status comparisons most consequential for psychosocial stress are typically among individuals who are in close geographic proximity or who occupy the same social network rather than between individuals at opposite ends of the socioeconomic spectrum. The importance of relative status perceptions to human psychology has its roots in the small-scale societies of our ancestors.""","Influence tends to peak when men are in their 30s or 40s, accrues to those who have more support from kin and other allies, and is linked with greater reproductive success . Our confidence in the validity of the influence measure is strengthened by ethnographic observation. Men ranked as influential spoke more often during community meetings attended by C.v.R.","[2.0, 1.0, 3.0, 2.0]",Psychology,train,2.0,news,http://www.technology.org/2014/10/15/even-among-egalitarian-forager-farmers-social-status-can-impact-health-happiness/
10.1098/rspb.2014.2515,Psychology_540,"The finding could go a long way in explaining their evolutionary success as survivors able to adapt to inhospitable environments, the scientists at the Universite Libre de Bruxelles say.","In conclusion, the individuals of P. americana showed behavioural stability over one week.","The finding could go a long way in explaining their evolutionary success as survivors able to adapt to inhospitable environments, the scientists at the Universite Libre de Bruxelles say. If all cockroaches were the same ""personality-wise,"" then they should all exhibit identical behavior. However, the researchers found, there were clear differences in behavior exhibited by individual cockroaches.","In the future, experiments with different quality shelters should reveal the optimal proportion of short-IRT/long-IRT individuals to reach the most efficient consensus decision-making. In conclusion, the individuals of P. americana showed behavioural stability over one week. This stability was observed for groups and for the individuals composing them.","[1.0, 1.0, 3.0, 1.0, 1.0]",Psychology,train,1.4,news,http://www.techtimes.com/articles/38804/20150310/the-timid-cockroach-researchers-find-the-insects-have-personalities.htm
10.1016/j.biopsych.2013.03.006,Psychology_541,"They zeroed in on abnormal folds and abnormal cell growth in the placenta, known as trophoblast inclusions.The placentas from the at-risk pregnancies were eight times more likely to have two or more of these abnormal folds than samples from not-at-risk deliveries.","Correlating known causes for tissue dysmorphisms, either secondary to endogenous (genetic) (42) or exogenous (environmental or maternal pregnancy related) developmental regulators, might be a good starting point for such studies.","At delivery, the placenta, also called the afterbirth, follows the baby out of the womb.The placentas from women whose older children had autism were markedly different from the others, Kliman's team found. They zeroed in on abnormal folds and abnormal cell growth in the placenta, known as trophoblast inclusions.The placentas from the at-risk pregnancies were eight times more likely to have two or more of these abnormal folds than samples from not-at-risk deliveries. Placentas with four or more of the inclusions predicted an infant with at least a 74 percent probability of being at risk for autism, the researchers said.","Our results suggest that examination of the genes, metabolic, and developmental pathways that regulate cell proliferation, tissue folding, and branching morphogenesis might be fruitful lines to investigate potential etiologic factors for ASD . Correlating known causes for tissue dysmorphisms, either secondary to endogenous (genetic) (42) or exogenous (environmental or maternal pregnancy related) developmental regulators, might be a good starting point for such studies. Increased circulating 5-HT LRϩ, the positive likelihood ratio; LRÀ, the negative likelihood ratio; other abbreviations as in Table 1 .","[3.0, 4.0, 4.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.webmd.com/brain/autism/news/20130425/newborns-placenta-may-predict-autism-risk-study-suggests
10.1177/1075547014549481,Psychology_542,"The other obstacle, anchoring, emerged in a quarter of all subjects.","As the data elicited are entirely participant generated, it facilitates a glimpse into how people mobilize their naturalistic chains of association in apprehending a given topic.","Similarly, they heard science and immediately tied it to highfalutin images of school, animal research, and scientific equipment. The other obstacle, anchoring, emerged in a quarter of all subjects. Researchers found people commonly used the imagery of textbooks and classrooms as anchors for science, as opposed to a more general method of inquiry and skepticism that people can apply in their daily lives.","This method reconstitutes free association, a technique historically associated with psychoanalytic clinical practice, into a research tool. As the data elicited are entirely participant generated, it facilitates a glimpse into how people mobilize their naturalistic chains of association in apprehending a given topic. This provided insight into participants' most likely sites of contact with neuroscientific information and also ensured that the sample was socioeconomically diverse, since in the United Kingdom broadsheets are associated with higher and tabloids with lower socioeconomic readerships .","[1.0, 2.0, 3.0, 1.0]",Psychology,train,1.75,news,http://www.medicaldaily.com/neuroscience-confusing-and-irrelevant-lot-people-309766
10.1146/annurev-clinpsy-032511-143041,Psychology_543,"We cannot solve addiction magically, by circumventing people's consciousness and lived experience in society.",The simplest explanation of this difference is that alcohol is legal and therefore more available.,"We've proven the futility of the brain-in-isolation approach a million times over. We cannot solve addiction magically, by circumventing people's consciousness and lived experience in society. Instead, we need to use these dimensions of human experience to make people happier, to feel that they belong on earth, and to realize that they are able to control their lives.","For instance, the half-life of alcohol dependence was about four times longer than the half-life of cocaine dependence (16 and 4 years, respectively). The simplest explanation of this difference is that alcohol is legal and therefore more available. However, during Prohibition, when alcohol was illegal, rates of drinking eventually crept back up to about 70% of their pre-Prohibition level .","[4.0, 2.0, 1.0, 2.0]",Psychology,train,2.25,news,http://reason.com/archives/2015/03/08/is-addiction-a-chronic-brain-disease
10.1016/j.cobeha.2016.09.013,Psychology_545,But it isnat just from watching their behavior that we can say animals are sentient.,"In general, it appears that a wide range of manipulations that are likely to either alter perceived prior probabilities of punishment and reward and/or alter the state of the animals so as to alter their payoffs from reward and punishment, produce predicted shifts in optimism (for recent examples see [17 ,19,20,25, 29,31,32,36-38,41,63-65] ).","Capuchin monkeys know when they are receiving unequal pay (grapes vs. cucumber), and Macaques develop individual cultures, particularly when it comes to how one should wash a potato. But it isnat just from watching their behavior that we can say animals are sentient. When we examine the brains of species (and indeed individuals), we can draw parallels from what we know about human brains and start to make assumptions.","Reducing feather condition might impair flight and increase the costs of dealing with a predation attempt, and hence increase pessimism that ambiguous cues predict punishment . In general, it appears that a wide range of manipulations that are likely to either alter perceived prior probabilities of punishment and reward and/or alter the state of the animals so as to alter their payoffs from reward and punishment, produce predicted shifts in optimism (for recent examples see [17 ,19,20,25, 29,31,32,36-38,41,63-65] ). The link between optimistic biases and affect is strengthened by results showing that optimistic biases measured using judgement bias tasks correlate with established measures of subjective mood in human subjects [26, 27] .","[2.0, 2.0, 2.0, 3.0]",Psychology,train,2.25,news,http://ct.moreover.com/?a=39011299495&p=1pl&v=1&x=KZTtXiAJj0fscGg6ZqBC8w
10.1044/1092-4388(2011/10-0155),Psychology_546,Children can have better outcomes if they receive help before they start school.,"The internal reliability (Cronbach's alpha) of the emotional symptoms sub-scale was moderate for teachers (α = 0.75), but moderate-low for parents (α = 0.66).","Do not wait until your child starts school to seek help. Children can have better outcomes if they receive help before they start school. Vocabulary and long-term outcomes

The amount and types of words addressed to children in the home from a young age correlates with their growing vocabulary.","The correlation between the scores on the two Academic Rating Scales was high (r = 0.81). The internal reliability (Cronbach's alpha) of the emotional symptoms sub-scale was moderate for teachers (α = 0.75), but moderate-low for parents (α = 0.66). The internal reliability (Cronbach's alpha) of the persistence scale was high (α = 0.84).","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.healthcanal.com/child-health/55579-how-to-tell-if-your-child-has-a-speech-or-language-impairment.html
10.1073/pnas.1400724111,Psychology_547,"""Our results suggest people are willing to bend ethical rules to help the people close to us, like our team or family,"" explained Dr. Shaul Shalvi of BGU's Department of Psychology.","The main effect for block was also significant, with participants taking more time in the loss trials (mean, 2.74; standard deviation, 1.09) than in the gain trials (mean, 2.42; standard deviation, 0.89) and no-benefit trials [mean, 2.46; standard deviation, 0.68; F(1,58) = 3.62; P = 0.033].","Aware that they could fudge the results -- dishonestly recording correct prediction -- for the benefit of their group, those given oxytocin at the beginning were more likely to do so. ""Our results suggest people are willing to bend ethical rules to help the people close to us, like our team or family,"" explained Dr. Shaul Shalvi of BGU's Department of Psychology. ""Together, these findings fit a functional perspective on morality revealing dishonesty to be plastic and rooted in evolved neurobiological circuitries, and align with work showing that oxytocin shifts the decision-maker's focus from self to group interests.""","A 2 (oxytocin vs. placebo) × 3 (loss vs. none vs. gain trial block) ANOVA with trial block within subjects revealed faster reporting about whether predictions were correct among participants receiving oxytocin (mean, 2.22 seconds ; standard deviation, 0.50) than placebo [mean, 2.86 seconds ; standard deviation, 0.78; F(1,58) = 13.99; P < 0.00001]. The main effect for block was also significant, with participants taking more time in the loss trials (mean, 2.74; standard deviation, 1.09) than in the gain trials (mean, 2.42; standard deviation, 0.89) and no-benefit trials [mean, 2.46; standard deviation, 0.68; F(1,58) = 3.62; P = 0.033]. The interaction between oxytocin and block was not significant (F < 1; P > 0.65).","[1.0, 3.0, 1.0, 2.0, 1.0]",Psychology,train,1.6,news,http://www.upi.com/Science_News/2014/04/04/Love-hormone-Oxytocin-moves-groups-to-lie/2171396638907/
10.1177/2156587216668109,Psychology_548,"It has, thus far, proved to be a successful mission.",Feeling of spiritual well-being significantly increased across all participants (P < .001).,"Personally, [singing bowls] have allowed me to get the most out of my practice throughout the past decade, and they might be just what people need to take that next step forward. It has, thus far, proved to be a successful mission. ""New experiences forced me to ask new questions,"" he explains.","Additionally, participants who were previously naïve to this type of meditation experienced a significantly greater reduction in tension compared with participants experienced in this meditation (P < .001). Feeling of spiritual well-being significantly increased across all participants (P < .001). Tibetan singing bowl meditation may be a feasible low-cost low technology intervention for reducing feelings of tension, anxiety, and depression, and increasing spiritual well-being.","[4.0, 1.0, 1.0, 3.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39127010899&p=1pl&v=1&x=x56XAbzzT6bprDTX9w2EPA
10.1177/1548051814538099,Psychology_549,More information regarding the findings can be seen in the Journal of Leadership & Organizational Studies.,"Third, our conceptual model builds on findings from behavioral economists such as who have highlighted that people often demonstrate commitment and consistency even when it makes no rational sense.","Study findings also revealed that former varsity athletes were significantly more likely to volunteer and engage in other charitable organizations. ""In our study of late-career workers, those who earned a varsity letter more than 50 years ago do demonstrate these characteristics more than others - plus, they donate time and money more frequently than others and possessed great prosocial behavior in their 70s, 80s, and 90s,"" said Kniffin. More information regarding the findings can be seen in the Journal of Leadership & Organizational Studies.","In this perspective and in light of social exchange theory , it is valuable to recognize that participants in team sports tend to engage in very intense ""reciprocal trading"" or ""exchange"" relationships with teammates and -following -there is reason to expect that participation in frequent exchange will correlate with an overall sense of fairness and organizationally beneficial traits that extend beyond the team. Third, our conceptual model builds on findings from behavioral economists such as who have highlighted that people often demonstrate commitment and consistency even when it makes no rational sense. Given that team sports are designed to reward group-level achievements and appear to facilitate the enforcement of group-serving behavior (e.g., , previous research on the role of consistent commitment to group norms helps to inform our interest and approach.","[1.0, 3.0, 1.0, 2.0, 3.0]",Psychology,train,2.0,news,http://www.scienceworldreport.com/articles/15520/20140618/are-former-athletes-ahead-of-the-game-in-the-job-market.htm
10.1001/jamapsychiatry.2018.1941,Psychology_55,Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample.,CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.,"Among those with depression, researchers found a strong connection between the dorsolateral prefrontal cortex, which is associated with short-term memory; the precuneus, which is associated with the self, and the lateral orbitofrontal cortex, which is associated with negative emotion. Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality. An important finding was that the Depressive Problems scores in this general population were correlated with functional connectivities between areas, including the lateral orbitofrontal cortex, cingulate cortex, precuneus, angular gyrus, and temporal cortex.","[4.0, 3.0, 3.0]",Psychology,train,3.333333333333333,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1111/desc.12147,Psychology_550,"They're familiar with the setting and that helps them remember and use what they already know about nonsolids.""",That this systematic difference was found on pieces trials supports earlier research demonstrating the role of stimuli on NNG behavior .,"""And, if you expose them to these things when they're in a highchair, they do better. They're familiar with the setting and that helps them remember and use what they already know about nonsolids."" Not surprisingly, many children gleefully dove into this task by poking, prodding, touching, feeling, eating -- and yes, throwing -- the nonsolids in order to understand what they were and make the correct association with the hypothetical names.","This is clear in Figure 2 , which shows the distribution of individual children's NNG performance on the pieces trials for each condition. That this systematic difference was found on pieces trials supports earlier research demonstrating the role of stimuli on NNG behavior . We add to this by showing that the context in which children typically learn names for nonsolids, a highchair, affects the way they generalize new names in the lab.","[1.0, 1.0, 1.0, 4.0]",Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/12/131202082318.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1073/pnas.0601428103,Psychology_551,How we think can ultimately be influenced by the society in which we live.,"If memes with both positive and negative values of µ are possible, the process of cognitive explosion is expected to be delayed as deleterious memes will occasionally spread through the population Wednesday 6 th February, 2008 2:46pm 13 like an epidemic reducing the fitness advantage of having high cognitive abilities.","How we think can ultimately be influenced by the society in which we live. The same is also somewhat true for wasp species, when it comes to certain evolved social behaviors that is. ""By relying on group mates, insect colony members may afford to make less individual brain investment.","will quickly spread their genes across the whole system. If memes with both positive and negative values of µ are possible, the process of cognitive explosion is expected to be delayed as deleterious memes will occasionally spread through the population Wednesday 6 th February, 2008 2:46pm 13 like an epidemic reducing the fitness advantage of having high cognitive abilities. Selective imitation when memes are more likely to be learned from high fitness/status individuals, should accelerate the evolution of brain size.","[1.0, 3.0, 1.0, 1.0]",Psychology,train,1.5,news,http://www.scienceworldreport.com/articles/26902/20150619/insects-and-social-behavior-some-insect-societies-appear-to-share-brain-power.htm
10.1007/s40279-018-0916-2,Psychology_553,"(c) Getty / skynesher Getty / skynesher

When you're on the home stretch of a run, so close to being done, your cooldown is probably the last thing on your mind.","An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter.","(c) Getty / skynesher Getty / skynesher

When you're on the home stretch of a run, so close to being done, your cooldown is probably the last thing on your mind. If you're like me, your train of thought is more like, ""Come on, you're almost there, when did this street get so long, are we done yet?!"" This comes down to the unsurprising fact that hard exercise, like running, has a major effect on your blood flow.","Strategies that enhance the resynthesis of glycogen may therefore attenuate the decrease in performance and even enhance performance. An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter. Therefore, these findings suggest that an active cool-down may interfere with muscle glycogen resynthesis, particularly within type I muscle fibers , because these fibers are preferentially recruited during a low-to moderate-intensity active cool-down.","[2.0, 3.0, 3.0, 2.0, 3.0]",Psychology,train,2.6,news,http://ct.moreover.com/?a=39141473736&p=1pl&v=1&x=_efL0_5lr2Hi4R9IIF01jw
10.1016/j.chb.2015.03.067,Psychology_554,"""In a nutshell, the more users put into the forum, the more they get back, and the pay-off for both users themselves and society at large can be significant,"" added Jessica Salvatore, a researcher at Sweet Briar College.",Patterns of identification with different ingroups suggest that identification occurs when it is functional (useful).,"""In fact, as well as finding answers, our study showed users often discover that forums are a source of great support, especially those seeking information about more stigmatizing conditions."" The study also found that the more involved online forum users became, the more likely they were to get positive benefits out of their experience. ""In a nutshell, the more users put into the forum, the more they get back, and the pay-off for both users themselves and society at large can be significant,"" added Jessica Salvatore, a researcher at Sweet Briar College.","In other words, instead of taking identification levels as a ''given,'' we need to conceptualize them also as a dynamic outcome. Patterns of identification with different ingroups suggest that identification occurs when it is functional (useful). Moreover, low identifiers will begin to identify with a group when they anticipate that the group is about to benefit from positive social change, but will dis-identify when change is unlikely .","[4.0, 1.0, 2.0, 1.0]",Psychology,train,1.0,news,http://www.upi.com/Science_News/2015/04/21/Study-Online-discussion-forums-promote-well-being/5621429644105/
10.1073/pnas.1706541114,Psychology_555,Which helps explain why 69% in a new SunTrust poll said they'd skip exchanging gifts this year if friends and family would agree to it.,It is possible that the time-saving and material purchases could differ in various ways.,"That could be welcome news if you're anything like me and about 10 zillion other Americans who are stressed to eyeballs about all those presents you still have to get; the typical consumer plans to buy 15 holiday gifts this year, a Deloitte survey reports. Which helps explain why 69% in a new SunTrust poll said they'd skip exchanging gifts this year if friends and family would agree to it. Favor giving experiences over stuff

Sixty percent of the money holiday shoppers shell out for presents this year will go to buy clothing, toys and electronics, Deloitte found.","All results also remain significant using two-tailed tests. It is possible that the time-saving and material purchases could differ in various ways. We provide evidence that using money to buy time can provide a buffer against this time famine, thereby promoting happiness.","[3.0, 4.0, 1.0]",Psychology,train,2.0,news,http://www.marketwatch.com/news/story.asp?guid=%7BC1E37374-DF95-11E7-88F6-D243BDA3944B%7D&siteid=rss&rss=1
10.1177/0305735605050650,Psychology_556,"Wer hingegen Aufgaben erledige, die wenig Aufmerksamkeit abverlangen, konne getrost auf seine Lieblingsmusik setzen, erklart die Expertin.","While a control company was considered in the planning of the design, it became evident that each company was very individual.",",,Der Gerauschpegel der Musik darf die eigenen Gedanken im Kopf nicht ubertonen."" Wer hingegen Aufgaben erledige, die wenig Aufmerksamkeit abverlangen, konne getrost auf seine Lieblingsmusik setzen, erklart die Expertin. Perfekte Playlist erstellen: Der erste Song ist die Visitenkarte

Simone Schiborr kennt sich aus mit dem Effekt von Musik auf die Arbeitsweise der Menschen.","Music listening may provide an opportunity for developers to align themselves with their optimum creativity. While a control company was considered in the planning of the design, it became evident that each company was very individual. There was an absence of a guided listening framework for the developers.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39219900442&p=1pl&v=1&x=hMfQUbQXOVGBrTjzb8OL7A
10.1038/s41398-018-0279-3,Psychology_557,An den Studien nahmen 154 bzw.,"As shown before in this sample , controls and CU (lowLevCU + highLevCU) differed significantly in the GCI and all four domains (F(1148) = 10.64-28.34, p ≤ 0.001) (Table S5 ).","Wie Menschen ihre Umwelt wahrnehmen, wie sie fuhlen und sich erinnern: All das geschieht wesentlich in der Hirnrinde. An den Studien nahmen 154 bzw. Deshalb drangt er darauf, Drug-Checking-Programme unbedingt auszubauen, damit Konsumierende ihr erworbenes Kokain auf seine Zusammensetzung untersuchen lassen konnen.","Additionally, hair samples and cumulative doses revealed a clear dominance of cocaine compared with other illegal drugs, as intended by the inclusion and exclusion criteria. As shown before in this sample , controls and CU (lowLevCU + highLevCU) differed significantly in the GCI and all four domains (F(1148) = 10.64-28.34, p ≤ 0.001) (Table S5 ). Three-group ANCOVAs (controls vs. lowLevCU vs. highLevCU) for the GCI (F(2147) = .26, p < 0.001) and across all four cognitive domains (F(2147) = 6.70-10.45, p = 0.002-0.0001) showed significant group effects (Fig.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37572208046&p=1pl&v=1&x=vHXZXNXTUUHNwOc40tnI9Q
10.1093/jcr/ucw012,Psychology_56,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","The results show that behaviorally targeted ads result in increased purchase intentions for the advertised product, an effect mediated by consumers' recognition of the ad as an implied social label.","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","The effects proposed in hypotheses 1 and 2 only hold when the implied label is plausibly connected to consumers' prior behavior (i.e., when behavioral targeting is at least moderately accurate). The results show that behaviorally targeted ads result in increased purchase intentions for the advertised product, an effect mediated by consumers' recognition of the ad as an implied social label. Study 2 demonstrates that the effects of behavioral targeting on purchase intentions are mediated by the recognition that the ad implies something about the consumer's identity and the subsequent adjustments in self-perceptions that result from recognizing this implied label.","[4.0, 5.0, 3.0, 4.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jaac.2016.10.016,Psychology_560,"If the medication is stopped, bone density catches up to normal after a few years as the child goes through the puberty of their gender assigned at birth.","Only 1 parent was present for participation with the control children, and therefore only 1 parent completed an assessment.","The only significant side effect is that the adolescent may fall behind on bone density. If the medication is stopped, bone density catches up to normal after a few years as the child goes through the puberty of their gender assigned at birth. Alternatively, if an adolescent continues to identify as transgender and starts on gender-affirming hormones like estrogen or testosterone down the line, this will also catch them up on bone density.","Of the 38 siblings who filled out anxiety and depression measurements, 25 children had 2 parents who completed assessments and 13 children had 1 parent who completed the assessments. Only 1 parent was present for participation with the control children, and therefore only 1 parent completed an assessment. For consistency with past work, 24 when children had 2 parent reporters, the responses of the 2 parents was averaged (in general, the 2 parents' responses were associated: depression, r =0.508, p <.001, n =61; anxiety, r =0.470, p <.001, n =61).","[3.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.8,news,http://ct.moreover.com/?a=37465391011&p=1pl&v=1&x=fUzMSG56d7LRaFjvh1V32g
10.1111/joop.12120,Psychology_561,"They must be told that it's a jungle out there, in which you must learn to avoid danger.",proposed that 'appropriately cast expectations for the effects of such programs are essential for their implementation' (p. 153).,"I submit that this is what our daughters--and apparently, our Supreme Court nominees--need. They must be told that it's a jungle out there, in which you must learn to avoid danger. They must be told to defend yourself if attacked; and if that fails, to pick yourself up and keep going.",A possible explanation for this finding is that the lower morale may have reflected less perceived helplessness of behaviour by commanders and yielded an impression that such programmes do not provide benefit. proposed that 'appropriately cast expectations for the effects of such programs are essential for their implementation' (p. 153). The most frequently studied category of dependent variables was mental health and subjective well-being.,"[1.0, 3.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37323580465&p=1pl&v=1&x=0goYu0CtazuLJ66qWQ0nTQ
10.1038/s41562-018-0425-1,Psychology_562,"Demonstrating purity of intent will only take you so far, of course.","At first glance, this interaction may seem surprising because our model only predicts a main effect of agent and does not differentiate between positive and negative updating.","Getting It Right the Second Time Around

I've certainly blown more than one first impression (entrepreneurs get lots of swings at the first impression plate) and have successfully followed a specific pattern to recover. Demonstrating purity of intent will only take you so far, of course. Phoniness at this point will be nuclear for the relationship, so ensure sincerity.","The main effects were qualified by an interaction between agent and shift direction (Kruskal-Wallis, P < 0.001), in which asymmetric updating was more pronounced when morality improved than when morality worsened (Fig. At first glance, this interaction may seem surprising because our model only predicts a main effect of agent and does not differentiate between positive and negative updating. Thus, when a 'good' agent's behaviour suddenly worsens, participants may infer a potential threat, prompting their beliefs about the agent to become more uncertain and amenable to rapid updating.","[1.0, 1.0, 2.0]",Psychology,train,1.3333333333333333,news,http://ct.moreover.com/?a=37338369969&p=1pl&v=1&x=yRWClNlwF_jHdp9NcY19wg
10.1177/0956797614545133,Psychology_563,"They simultaneously (and somewhat improbably) like both Kanye West and Kenny Chesney.""","The trend is not limited to distrust in government; the declines also appear in Americans' confidence in institutions unconnected to the government, such as medicine, religion, the news media, and TV.","But, for better or worse, these trends actually have more to do with the age we're in and the tech we use than they do with kids today. They simultaneously (and somewhat improbably) like both Kanye West and Kenny Chesney."" Most of these qualifiers aren't distinct to millennials.","These results suggest that Americans are increasingly less likely to trust others, both on an individual level and as a collective. The trend is not limited to distrust in government; the declines also appear in Americans' confidence in institutions unconnected to the government, such as medicine, religion, the news media, and TV. This decline in confidence is consistent with the lower concern for others and civic engagement found among Millennials and with the higher individualism among both individuals and the culture in recent years .","[1.0, 2.0, 1.0, 3.0]",Psychology,train,1.75,news,http://www.slate.com/articles/technology/future_tense/2014/12/you_don_t_hate_millennials_you_hate_21st_century_technology.html
10.1016/j.neuron.2015.08.026,Psychology_564,"The study helps explain what makes the healthy behavior work, Badre says, and could also provide important information for psychiatrists and neurologists in clinical cases.","Rather, it is evident that ramping activation is restricted to a distributed, yet specific, set of regions.","The researchers watched and manipulated other brain regions during the experiments but the RLPFC was unique in increasing its activity as people moved unguided through a sequence, and unique in yielding an increasing likelihood of error if perturbed later into the task sequences. The study helps explain what makes the healthy behavior work, Badre says, and could also provide important information for psychiatrists and neurologists in clinical cases. ""The health consequences are big,"" Badre says.","Thus, while the ramping effect in RLPFC is not fully localized to one and only one region (in a classical cognitive localization sense), neither is ramping activation universal or unpredictably distributed throughout the brain. Rather, it is evident that ramping activation is restricted to a distributed, yet specific, set of regions. The ramping activation in superior temporal cortex was outside of the network that correlates with RLPFC at rest.","[1.0, 1.0, 1.0, 3.0, 3.0]",Psychology,train,1.8,news,http://www.futurity.org/tasks-rostrolateral-prefrontal-cortex-1012312-2/
10.1016/j.psyneuen.2018.08.007,Psychology_565,"And as the participants were relatively young and inflammations worsen with age, older couples could suffer worse, the researchers said.","There was not a significant association between sCD14 AUC G and either mood disorder history (p = 0.59) or hostile behavior (p = 0.22), but the trend was for more hostile behaviors to be associated with lower sCD14.","In turn, bacteria triggering inflammation in the blood could lead to mental illness in what Bailey described as a troubling loop. And as the participants were relatively young and inflammations worsen with age, older couples could suffer worse, the researchers said. But it's also relatively easy to mitigate the effects of marital stress by eating a diet packed with lean proteins, healthy fats, fruits, whole grains, vegetables, and consuming probiotics, said Kiecolt-Glaser.","The effect of mood disorder history was not significant (p = 0.13) but trended towards higher LBP AUC G among participants with a mood disorder history. There was not a significant association between sCD14 AUC G and either mood disorder history (p = 0.59) or hostile behavior (p = 0.22), but the trend was for more hostile behaviors to be associated with lower sCD14. There was a significant interaction of hostile behavior and mood disorder history in predicting the LBP/sCD14 ratio (p = 0.01, Fig.","[1.0, 1.0, 3.0]",Psychology,train,1.6666666666666667,news,http://ct.moreover.com/?a=34863080170&p=1pl&v=1&x=UfggZex8Kn_6wT42BWSTeg
10.1177/0265407511431185,Psychology_568,"Cu alte cuvinte, nu te pune sa faci sex daca nu vrei asta pe bune.","This positive link between the intensity of daily hassles on a given day and the probability of having sexual intercourse on the subsequent day was only significant for women high on relationship satisfaction, g ¼ .26, p ¼ .0024, but not for women low on relationship satisfaction, g ¼ .15, p ¼ .14.","Studiile au demonstrat ca atunci cand oamenii se forteaza sa faca sex, nivelul de fericire le scade - ceea ce e opusul a ceea ce vrei sa obtii. Cu alte cuvinte, nu te pune sa faci sex daca nu vrei asta pe bune. In schimb, ti-ar prinde bine sa-i asculti sfatul lui Leavitt si sa te concentrezi asupra eliminarea barierelor puse in calea intimitatii fizice, cum ar fi raspunsul la telefoane si mailuri de munca seara tarziu.","Using method to calculate the difference between simple slopes in three-way interactions, we found that for men, the greater the intensity of daily hassles on a given day, the greater the probability of having sexual intercourse on the subsequent day: however, this link was marginally stronger for men low on relationship satisfaction (one standard deviation below the mean of relationship satisfaction; g ¼ .94, p < .001) than for men high on relationship satisfaction (one standard deviation above the mean of relationship satisfaction; g ¼ .40, p ¼ .0075), t(295) ¼ 1.80, p ¼ .07. This positive link between the intensity of daily hassles on a given day and the probability of having sexual intercourse on the subsequent day was only significant for women high on relationship satisfaction, g ¼ .26, p ¼ .0024, but not for women low on relationship satisfaction, g ¼ .15, p ¼ .14. The difference between these slopes, however, was not significant, t(295) ¼ .26, p ¼ .80.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=32511889906&p=1pl&v=1&x=3aDCLX9pRoPNtOhsHbwH0A
10.1007/s00424-013-1271-7,Psychology_569,But anxiety isn't objective--a white-coated lab tech can't look down a microscope and diagnose it.,"Concordantly, excitatory stimulation of the DPAG/DLPAG in primates and (electrically) in awake non-panic disorder human patients [173] causes panic-like emotional and autonomic responses (e.g., tachycardia and hyperventilation) and, when increased in intensity, a shift from reactive freezing behavior to active escape in rodents .","But anxiety isn't objective--a white-coated lab tech can't look down a microscope and diagnose it. Therefore, as a clinical psychologist and anxiety specialist, I'd be willing to bet the canyon between the numbers of men and women who report having anxiety is more like a crack in the sidewalk. While the science is still emerging on the biology of anxiety in men and women, I think the difference has a lot to do with how anxiety manifests.","Namely, Lister hooded rats respond with tachycardia and hyperthermia to a noninvasive 22-kHz (typical frequency for an adult rat) ultrasound stressor without altering HPA axis function, and this is associated with increased c-fos activation of the DPAG/dorsolateral periaqueductal gray (DLPAG) . Concordantly, excitatory stimulation of the DPAG/DLPAG in primates and (electrically) in awake non-panic disorder human patients [173] causes panic-like emotional and autonomic responses (e.g., tachycardia and hyperventilation) and, when increased in intensity, a shift from reactive freezing behavior to active escape in rodents . Such protocols appear to be most successful in modeling increased vulnerability in females.","[1.0, 1.0, 2.0, 1.0]",Psychology,train,1.25,news,http://ct.moreover.com/?a=38484813321&p=1pl&v=1&x=6B4cimduB5hDk2g8-YzlfA
10.1177/0956797610384745,Psychology_572,The difficulty of weight loss should not be an excuse not to improve.,"Similarly, for accuracy on the IQ problems, only the interaction between self-reported exhaustion and implicit-theory condition remained significant when both self-reported exhaustion and ego-depletion condition were included in the analysis, β = 0. resources.","Now, don't interpret this as ""you're not in control so don't even worry about it."" The difficulty of weight loss should not be an excuse not to improve. On the contrary, you should use this information to understand the setbacks, and help you overcome them in order to become the best version of yourself.","For accuracy on the Stroop task, the interaction between selfreported exhaustion and implicit-theory condition remained significant, β = 0.18, OR = 1.20, t(1840) = 3.55, p < .01, but the interaction between ego-depletion condition and implicittheory condition was no longer significant, β = 0.14, OR = 1.15, t(1840) = 1.56, p > .10, Sobel test: z = 2.20, p < .05. Similarly, for accuracy on the IQ problems, only the interaction between self-reported exhaustion and implicit-theory condition remained significant when both self-reported exhaustion and ego-depletion condition were included in the analysis, β = 0. resources. After a depletion manipulation, participants in the nonlimited-resource-theory condition showed no evidence of resource depletion even on a series of tasks.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://vitals.lifehacker.com/why-eat-less-move-more-is-the-least-helpful-diet-adv-1686146359
10.1111/jcom.12160,Psychology_573,"Under normal drug development proceedings, a pharmaceutical startup would submit such preclinical work to peer review to support any claims and use it to drum up funding for clinical testing.",The results regarding content features and an editorial cue to news importance have practical implications for web-based public health communication campaigns where messages and their positions on a webpage are determined a priori.,"It was an especially brash move considering the company has not conducted a single trial in humans or published an ounce of data from its completed studies of petri dish cells and rodents in cages. Under normal drug development proceedings, a pharmaceutical startup would submit such preclinical work to peer review to support any claims and use it to drum up funding for clinical testing. AEBi's PR move might be an attempt at a shortcut.","Thus, more research is warranted to test psychological mechanisms that underlie the retransmission-channel effects in health contexts, including the role of narrowcasting-and broadcasting-related news-sharing motivations . The results regarding content features and an editorial cue to news importance have practical implications for web-based public health communication campaigns where messages and their positions on a webpage are determined a priori. Specifically, the results can be used to quantify what consequences in audience selection and sharing would follow from manipulating the content and editorial factors.","[1.0, 2.0, 2.0, 1.0]",Psychology,train,1.5,news,http://ct.moreover.com/?a=38406316939&p=1pl&v=1&x=IK0fhvY6HMEq5xibJx5ZFA
10.1002/per.1944,Psychology_574,"He and his collaborators have found that leaders who make other people feel good by their very presence have teams that are better at sharing information, which leads to more innovation.",This gives approximately 80% statistical power for a partner effect estimate of 0.3 with three groups when N = 12 .,"They also got more romantic interest from others in a separate speed-dating study. He and his collaborators have found that leaders who make other people feel good by their very presence have teams that are better at sharing information, which leads to more innovation. Subordinates are more likely to voice their ideas, too, to a leader with positive affective presence.","1 This indicated that it was legitimate to pool results from men and women, which means that the asymmetric design can be considered for data analysis purposes as a symmetric block design . This gives approximately 80% statistical power for a partner effect estimate of 0.3 with three groups when N = 12 . Table 1 shows the SRM variance partitioning both for positive affect and negative affect and for the discrete emotions that comprise these dimensions.","[1.0, 3.0, 1.0, 2.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=38187278803&p=1pl&v=1&x=ymIvxmO4LWnEtrUCGqoaAQ
10.1177/0269881117748902,Psychology_575,"Las visiones pueden irse despues de unas horas, pero investigaciones recientes en psilocibina, el componente activo de los hongos magicos, sugiere que tomar psicodelicos deja una huella en tu personalidad, y construye creencias que perduran incluso despues de que el viaje se termina.","captured by nature relatedness) may be assigned the greatest importance , particularly when considering the scale and seriousness of the problem posed by climate change, for example , whereas others may recognise 'order' (e.g.","Las alucinaciones no son la unica forma en que un viaje psicodelico cambia tu manera de ver el mundo. Las visiones pueden irse despues de unas horas, pero investigaciones recientes en psilocibina, el componente activo de los hongos magicos, sugiere que tomar psicodelicos deja una huella en tu personalidad, y construye creencias que perduran incluso despues de que el viaje se termina. Tus opiniones politicas, tu personalidad y la forma en que te sientes conectado con el mundo y la naturaleza pueden cambiar despues de unas dosis de psilocibina, segun un estudio publicado en enero por investigadores de la Universidad Imperial de Londres en el Reino Unido.","For some, ecological considerations (e.g. captured by nature relatedness) may be assigned the greatest importance , particularly when considering the scale and seriousness of the problem posed by climate change, for example , whereas others may recognise 'order' (e.g. captured in part by our authoritarianism scale) as an essential and functional counterweight to lawlessness .","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=33330220127&p=1pl&v=1&x=Euv7IEAKZlqH93wf9ujofQ
10.1177/0269881116675513,Psychology_577,The first thing they want voters to know is that they're not following the model of legalization used by cannabis proponents.,"Eleven of 17 therapeutically relevant measures fulfilled conservative criteria for demonstrating efficacy of the high dose of psilocybin (Table 4, Figure 3 ).","That means the federal government thinks it has no medical application whatsoever -- and high potential for abuse. The first thing they want voters to know is that they're not following the model of legalization used by cannabis proponents. ""The most amazing thing happened; I just kind of found my identity, my sense of self completely turned into post-its -- little slips of paper that were being blown-around by the wind,"" Pollan recently told OPB's ""Think Out Loud.""","The present study demonstrated the efficacy of a high dose of psilocybin administered under supportive conditions to decrease symptoms of depressed mood and anxiety, and to increase quality of life in patients with a life-threatening cancer diagnosis. Eleven of 17 therapeutically relevant measures fulfilled conservative criteria for demonstrating efficacy of the high dose of psilocybin (Table 4, Figure 3 ). The data show that psilocybin produced large and significant decreases in clinician-rated and self-rated measures of depression, anxiety or mood disturbance, and increases in measures of quality of life, life meaning, death acceptance, and optimism.","[1.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=38138143850&p=1pl&v=1&x=u3EuzC0_5wVGL1c7fLtVbg
10.1080/02640410500189033,Psychology_578,"Based on this body of knowledge and empirical data, I would observe that Kipchoge's extraordinary and excellent performance has a lot to do with his mental strength, physical fitness, diet, and great running economy which enables him to utilize oxygen and generate energy more efficiently.","Although mirrored in Ethiopia , these findings are in stark contrast to the sedentary lifestyles of young Scottish children and the increasing prevalence of childhood obesity in the USA and UK .","And they have come up with several possible reasons to elucidate the phenomenal performance of Kenya runners. Based on this body of knowledge and empirical data, I would observe that Kipchoge's extraordinary and excellent performance has a lot to do with his mental strength, physical fitness, diet, and great running economy which enables him to utilize oxygen and generate energy more efficiently. Overall, there is an interplay between nature and nurture in the success of Kenyan runners.","In this study, a higher proportion of international (51%, P 5 0.002) and national athletes (42%, P 5 0.01) travelled farther than 5 km to school each day than controls (25%) ( Figure 5 ). Although mirrored in Ethiopia , these findings are in stark contrast to the sedentary lifestyles of young Scottish children and the increasing prevalence of childhood obesity in the USA and UK . Athletes also differed from controls in their method of travel to school, with a higher proportion of athletes running to school each day [controls 22%; national athletes 73% (P 5 0.001); international athletes 82% (P 5 0.001)].","[2.0, 1.0, 1.0, 4.0, 3.0]",Psychology,train,2.2,news,http://ct.moreover.com/?a=39323860641&p=1pl&v=1&x=PiUp3lDqquioy-l5iX3QaQ
10.1186/2044-7248-3-9,Psychology_579,"""Those who had the Sound of the Sea rated the seafood as significantly better tasting or enjoyable,"" he says.","In one study, for instance, people's ratings of the environment were affected by the music that was playing in the background .","""Given that it's so present these days, it's just impacting the way in which we perceive the world."" ""Those who had the Sound of the Sea rated the seafood as significantly better tasting or enjoyable,"" he says. The experiment (referenced in the Journal of Sensory Studies in 2010) shows how sound might be used to emphasize or draw people's attention to certain flavors of the dish.","whether they like it or not) may carry over to influence their perception (or rating) of any food or drink tasted while listening to that noise. In one study, for instance, people's ratings of the environment were affected by the music that was playing in the background . This crossmodal effect was especially noticeable when the perceived attributes of the music and environment failed to match up.","[3.0, 4.0, 1.0, 4.0, 5.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38341405066&p=1pl&v=1&x=4DvoVkUBBHCxSXFiLYZsAA
10.1177/0141076814565942,Psychology_58,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.",The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate.,"The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","Again, any impact of such exposure misclassification would likely be non-differential, thus contributing to a conservative assessment of the link between circumcision and ASD risk. The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate. Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration.","[1.0, 2.0, 4.0, 2.0]",Psychology,train,2.25,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1177/0956797615626564,Psychology_580,"The ability to ignore is a key part of the ability to pay attention, the researchers said.","Specifically, we found no main effect of trial type, F(1, 24) = 0.512, p = .481.","Although trying to disregard distractions might initially slow people down, the researchers concluded that over time, people are more efficient when they know what's not worth paying attention to. The ability to ignore is a key part of the ability to pay attention, the researchers said. ""This study, along with some recent work in which we measured brain activity while subjects responded selectively to stimuli presented in the midst of competing stimuli, highlights the importance of active suppression of those competing stimuli.","A 2 (trial type) × 4 (block) repeated measures ANOVA revealed that even when we discounted the possibility that target repetitions facilitated the benefits shown on ignore trials, the results were the same. Specifically, we found no main effect of trial type, F(1, 24) = 0.512, p = .481. We found a significant main effect of block, F(3, 72) = 9.311, p < .001, η p 2 = .28; RTs decreased over the course of the experiment.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/lFYSQPmM6pA/
10.1016/j.neuropharm.2017.12.041,Psychology_582,"""This is great news for patients,"" COMPASS executive chairman George Goldsmith said in a statement.","Indeed, there is evidence of blunting of positive mood with SSRIs .","COMPASS Pathways will begin running the first large-scale psilocybin clinical trial for treatment-resistant depression in Europe and North America within the next two years. ""This is great news for patients,"" COMPASS executive chairman George Goldsmith said in a statement. ""We are excited to be taking this work forward with our clinical trial on psilocybin therapy for treatment-resistant depression.","Relatedly, negative stimuli may be processed as especially salient, and thus be associated with greater amygdala responses e which are subsequently hyper-sensitive to intervention-led change. Indeed, there is evidence of blunting of positive mood with SSRIs . Since the majority of patients reported improvements with the treatment, most answered in the affirmative and described a greater willingness to accept all emotions post-treatment (including negative ones).","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=37555272820&p=1pl&v=1&x=o0QG7mZDLLzEGoO7VuvgTQ
10.1080/15283488.2017.1379907,Psychology_583,"""But that's not what we found.""","Tonia also spoke to the lack of interethnic-racial groups and families in her community or in the media to provide models for behavior: ""It's kinda' something I'm almost insecure about so I think that's why it's a challenge for me.""","""But that's not what we found."" Many multiethnic-racial individuals have a strong sense of self, the researchers found. Because of their connections to different races and ethnicities, participants also have an awareness and enhanced understanding of others' experiences.","In Eric's case, a ""mixed"" identity was something distinctly different from other ethnic-racial groups and one that was not explicitly recognized or affirmed. Tonia also spoke to the lack of interethnic-racial groups and families in her community or in the media to provide models for behavior: ""It's kinda' something I'm almost insecure about so I think that's why it's a challenge for me."" In fact, she spoke to moving to communities with more interethnic-racial social groups and individuals with mixed backgrounds as a positive change in her life.","[1.0, 3.0, 1.0, 1.0]",Psychology,train,1.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/Pe15pqZyF3w/
10.1093/jcr/ucw035,Psychology_584,But our pay equity work doesn't stop at gender.,"If men make a joint choice on an appetizer or a piece of real estate, for example, they may choose a more expensive alternative than if they choose with women or alone.","That's because women make $1.01 for every dollar men make in comparable positions--and we're committed to advancing equal pay more broadly as participants in The White House Equal Pay Pledge and the Equal Pay Pledge on Glassdoor. But our pay equity work doesn't stop at gender. As we've seen from the differences in the dates I just listed, we must also consider other factors that can contribute to inequality.","To use this insight, marketers may want to prompt men to make decisions with other men. If men make a joint choice on an appetizer or a piece of real estate, for example, they may choose a more expensive alternative than if they choose with women or alone. Finally, marketers using the compromise effect for new product introduction, positioning, product assortments, and product deletions need to consider whether the target consumers for their products are likely to purchase them in joint or individual decision-making contexts, as well as the likely gender composition of the decision-making pairs.","[2.0, 1.0, 1.0, 1.0]",Psychology,train,1.25,news,http://ct.moreover.com/?a=33767243329&p=1pl&v=1&x=FaK0W8SlN8Iq0vegzw9KZw
10.1073/pnas.1218772110,Psychology_585,"Those determined to be ""liberal and artistic"" liked singer Leonard Cohen and writer Oscar Wilde, while conservatives preferred Nascar racing and the film Monster-in-Law.","Positive cases are those classified by the model to belong to a target class (e.g., ""male"" or ""Democrat"").","Extroverts liked actress and singer Jennifer Lopez, while introverts gravitated toward the film The Dark Knight. Those determined to be ""liberal and artistic"" liked singer Leonard Cohen and writer Oscar Wilde, while conservatives preferred Nascar racing and the film Monster-in-Law. The predictions relied to a large degree on inference, by aggregating huge amounts of data: those predicted to be homosexual were tagged as such not because they clicked on sites about gay marriage, but because of their preferences in music and TV shows, for example.","Predictions. Positive cases are those classified by the model to belong to a target class (e.g., ""male"" or ""Democrat""). Thus, true positive cases are the cases that were correctly classified by the model as belonging to a target class, whereas false-positive cases were classified incorrectly as belonging to a target class.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.news.com.au/technology/news/facebook-likes-reveal-private-details-new-research-shows/story-fn7celvh-1226595179943
10.1038/nn.3794,Psychology_586,"""It was such a dramatic effect, it leapt out at us,"" said Carl Olson, a professor at Carnegie Mellon.","Paradoxical interactions conforming to this pattern do, however, occur in inhibition-stabilized networks 4 44 .","However, in the current study, the CNBC researchers found that when subjects were exposed to familiar and unfamiliar images in a rapid succession, their neurons -- especially the inhibitory neurons -- fired much more strongly and selectively to images the subject had seen many times before. ""It was such a dramatic effect, it leapt out at us,"" said Carl Olson, a professor at Carnegie Mellon. ""You wouldn't expect there to be such deep changes in the brain from simply making things familiar.","Because putative inhibitory neurons themselves exhibit strong response truncation, it seems implausible that they could impose response truncation on excitatory neurons. Paradoxical interactions conforming to this pattern do, however, occur in inhibition-stabilized networks 4 44 . The late phase of the visual response might depend in part on recurrent excitatory connections among these neurons.","[1.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.4,news,http://www.sciencedaily.com/releases/2014/08/140824152347.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_science+%28ScienceDaily%3A+Top+Science+News%29
10.1016/j.neuron.2012.11.001,Psychology_587,"But high EQ, detached-perspective individuals didn't.","Related to these findings, in the de Vito et al.","I probably would have lost it. But high EQ, detached-perspective individuals didn't. The study findings concluded that, indeed: ""People can self-distance in the heat of the moment, and doing so reduces aggressive thoughts, angry feelings, and aggressive behavior.""","The parietal lesion patients showed impaired performance on both the memory and constructed experience tasks (e.g., they generated fewer specific details than did controls), whereas the prefrontal lesion patients were impaired on the constructed experience task but not on the autobiographical memory task. Related to these findings, in the de Vito et al. Semantic dementia patients, who have severe deficits in semantic memory with relative preservation of episodic memory consequent to atrophy of the anterior temporal lobes, showed a reduction relative to controls in internal (episodic) details on the Autobiographical Interview when imagining the future, together with a preserved ability to generate internal details when remembering the past ; see Figure 2 ).","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39772412697&p=1pl&v=1&x=79f66nZogyZy2VpL7bwQ_Q
10.1093/qje/qjr001,Psychology_588,"""[O]ur results may have several different interpretations,"" the authors write.","Of these games, 316 (36%) were predicted wins for the home team, 245 (28%) were predicted losses, and 305 (35%) were predicted close games.","They found a 16 percent increase in births in February 2010 as well as an 11 percent increase the following month compared with the other years surrounding that time. ""[O]ur results may have several different interpretations,"" the authors write. Jesus Montesinos, of Xarxa Assistencial Universitaria de Manresa, in Barcelona, Spain, and colleagues added that despite being observational, the findings still provide ""a better understanding of human behavior, improve health care planning, and even aid government policy makers in stimulating or reducing birth rates.""","For ""predicted losses"" (spread > 3) the probability of a win is 41% or less. Of these games, 316 (36%) were predicted wins for the home team, 245 (28%) were predicted losses, and 305 (35%) were predicted close games. The greater number of predicted wins than losses reflects the inclusion in our sample of two relatively successful teams (Denver and New England).","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.medicaldaily.com/birth-rate-increased-after-spanish-soccer-clubs-triumph-regional-events-can-affect-weight-passion
10.1089/cap.2018.0030,Psychology_589,"Ketamine has a very different mechanism of action than standard treatments.""",The low attrition for treatment visits and the first posttreatment clinical assessment could reflect strong commitment to the study from patients and parents based on their intimate knowledge of the importance of research investigating new treatments for adolescent TRD.,"Ketamine has a very different mechanism of action than standard treatments."" They found that the treatment was well tolerated, with the participants showing an average decrease in CDRS scores of 42.5 percent. Five of the participants met the criteria for clinical response and remission.","This is somewhat surprising given the presence of some adverse events as noted above, especially for those adolescents that showed no clinical improvement throughout the study. The low attrition for treatment visits and the first posttreatment clinical assessment could reflect strong commitment to the study from patients and parents based on their intimate knowledge of the importance of research investigating new treatments for adolescent TRD. It could also reflect hopes and expectations on the part of patients and families for what ketamine treatment could deliver, based on the reports around that time in public media avenues on the promise of ketamine for depression.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34702469833&p=1pl&v=1&x=94veOCBqiZuIzGDDoP25Cw
10.1177/0141076814565942,Psychology_59,"The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD.","With 57 ASD cases in ritually circumcised boys and 4929 ASD cases in intact boys, the overall ASD risk in the age interval 0-9 years was 46% increased in ritually circumcised boys (HR ¼ 1.46; 95% CI: 1.11-1.93).","The researchers, who followed the boys up to the age of nine, found that almost 5,000 cases of ASD were diagnosed. The study's findings showed that, regardless of cultural background, circumcised boys may run a greater risk of developing ASD. The researchers noted they also made an unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.","When considered simultaneously, gestational age and mother's marital status were no longer independent ASD risk factors. With 57 ASD cases in ritually circumcised boys and 4929 ASD cases in intact boys, the overall ASD risk in the age interval 0-9 years was 46% increased in ritually circumcised boys (HR ¼ 1.46; 95% CI: 1.11-1.93). This was due to noticeably increased ASD risk in the first 0-4 years of life (HR ¼ 1.80; 95% CI: 1.25-2.60), but not in the 5-9 years age interval (HR ¼ 1.15; 95% CI: 0.75-1.77).","[4.0, 3.0, 3.0]",Psychology,train,3.333333333333333,news,http://psychcentral.com/news/2015/01/10/circumcision-linked-to-increased-risk-of-autism/79714.html
10.1016/j.cognition.2015.11.006,Psychology_591,"However, the study was only performed on right-handed students, so if you are an anxious lefty, these results may not apply to you.",Activation of BAS is linked to the experience of positive affect and goal-directed behaviour.,"After comparing the trajectory results with the questionnaires, those showing more inhibition veered left while trying to walk straight, and those with higher BAS leaned right. However, the study was only performed on right-handed students, so if you are an anxious lefty, these results may not apply to you. Thankfully, these results do not mean that if you are suffering from anxiety you're gonna walk into a manhole or towards traffic if it's on your left.","We discuss the implications of these findings for the neurobiological underpinnings of BIS and for the literature on spatial bias. Activation of BAS is linked to the experience of positive affect and goal-directed behaviour. In contrast, activation of BIS is linked to the experience of anxiety, increased sensitivity to threatening cues, and disruption of ongoing processes.","[1.0, 2.0, 4.0, 4.0]",Psychology,train,1.0,news,http://www.bustle.com/articles/137229-anxious-people-lean-left-more-than-less-inhibited-peers-according-to-studies
10.1073/pnas.1414495112,Psychology_592,"""Our findings help explain why humans make music.",The geographic and stylistic diversity of this sample make it ideal for testing candidate musical universals.,"Researchers said the latest findings suggest that music is powerful in helping bond societies together. ""Our findings help explain why humans make music. In countries like North Korea we can also see extreme examples of how music and mass dance can be used to unite and coordinate groups,"" he added.","22 and 26). The geographic and stylistic diversity of this sample make it ideal for testing candidate musical universals. In particular, the encyclopedic nature of this collection, with its intention of capturing the great diversity of musical forms worldwide, should tend to make this sample overrepresent the real level of global diversity, and thus make it a particularly stringent sample for testing cross-cultural statistical regularities.","[2.0, 3.0, 4.0, 3.0]",Psychology,train,3.0,news,http://www.counselheal.com/articles/14061/20150701/music-beats-connects-people-through-dancing.htm
10.1177/0265407512449400,Psychology_593,"However, Lambert and colleague's research suggests that describing our happy experiences to close friends and romantic partners is a better idea.","However, writing may also be instrumental in increasing the cognitive accessibility of the event in one's memory.","Bonding over complaints, commiseration or even gossip somehow feels more proper, realistic and grounded. However, Lambert and colleague's research suggests that describing our happy experiences to close friends and romantic partners is a better idea. Lambert's new study, however, extends research on gratitude to show that verbally expressing the gratitude we feel to people close to us helps increase and sustain our well-being above and beyond simply feeling or writing down gratitude.","Otherwise stated, people drew on a reservoir of positive events readily accessible to memory when they were asked about their current affective state. However, writing may also be instrumental in increasing the cognitive accessibility of the event in one's memory. Thus, why is sharing the experience with someone else unique from writing (as we found)?","[1.0, 2.0, 2.0, 1.0, 1.0]",Psychology,train,1.4,news,http://www.scientificamerican.com/article.cfm?id=share-your-good-news-and-you-will-be-better-off
10.1073/pnas.1417712112,Psychology_594,"Hungry shoppers bought more high-calorie foods, many of which were processed snacks and candy.","Finally, the positive influence of the hunger manipulation on acquisition held after including mood as a covariate [F(1, 58) = 6.61, P < 0.02].","There was, however, a difference in the quality of the foods added to their carts. Hungry shoppers bought more high-calorie foods, many of which were processed snacks and candy. Satiated shoppers tended towards lower-calorie foods such as fruits and fresh vegetables.","Mood did not influence the acquisition of binder clips (b = -0.048, SE = 0.208, t = -0.23, P > 0.80) or their evaluation (b = 0.058, SE = 0.119, t = 0.49, P > 0.60). Finally, the positive influence of the hunger manipulation on acquisition held after including mood as a covariate [F(1, 58) = 6.61, P < 0.02]. It also had a very small collection of snacks.","[4.0, 2.0, 1.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=38266299649&p=1pl&v=1&x=MW4yfkiVI0_h5qZVB4EQ8g
10.1007/s12529-014-9448-9,Psychology_595,"High vs. low MAAS scores were associated with significantly higher cardiovascular health on four of the seven individual indicators: BMI, physical activity, fasting glucose, and avoiding smoking.",These intervention findings are supported by a recent meta-analysis of 11 observational studies that showed significant inverse associations between dispositional mindfulness and smoking (aggregate r= −0.14; p<0.001) consistent with findings in the current study.,"Participants with high MAAS scores had an 83 percent greater prevalence of good cardiovascular health (as measured by the composite score) compared to those with relatively low MAAS scores. High vs. low MAAS scores were associated with significantly higher cardiovascular health on four of the seven individual indicators: BMI, physical activity, fasting glucose, and avoiding smoking. That higher mindfulness did not also associate with higher scores for blood pressure or cholesterol may be because neither of those health indicators directly affect how someone feels in a typical moment, whereas smoking, obesity (and closely related fasting glucose), and physical activity are all much more explicitly evident experiences for the self.","Prevalence Ratio methodologically rigorous randomized controlled trials to date demonstrated a 31 % smoking abstinence rate for those randomized to mindfulness training vs. 6 % in the active control group at 17 weeks follow-up (p= 0.012) . These intervention findings are supported by a recent meta-analysis of 11 observational studies that showed significant inverse associations between dispositional mindfulness and smoking (aggregate r= −0.14; p<0.001) consistent with findings in the current study. With regard to obesity, to our knowledge, this is the first study to evaluate associations of dispositional mindfulness with directly assessed BMI.","[3.0, 3.0, 2.0, 3.0]",Psychology,train,2.75,news,http://www.sciencedaily.com/releases/2014/10/141023100930.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1002/eat.20671,Psychology_596,"Toen ik als 17-jarige puber eenmaal een behandeling aanging voor mijn eetstoornis en ik in groepsverband werd behandeld met zowel anorexia- als boulimiapatienten, kwam ik erachter dat ik bij lange na niet de enige eetgestoorde persoon was met dergelijke ervaringen.","Third, the SIAB was not designed specifically to measure sexual functioning and therefore, these results are considered to be preliminary and motivational for future studies to use instruments designed to assess relationship and sexual functioning.","Mijn eerste vriendje deed op het moment supreme zijn uiterste best me op mijn gemak te stellen, maar ik was toch vooral bezig met het eetgestoorde stemmetje in mijn hoofd, dat ook tijdens mijn meest intieme momenten alles wist te vergallen. Toen ik als 17-jarige puber eenmaal een behandeling aanging voor mijn eetstoornis en ik in groepsverband werd behandeld met zowel anorexia- als boulimiapatienten, kwam ik erachter dat ik bij lange na niet de enige eetgestoorde persoon was met dergelijke ervaringen. Sterker nog, volgens een onderzoek dat in 2011 werd gepubliceerd, waaraan 242 vrouwen met eetstoornissen meededen, had 66,9 procent last van een ""verminderd libido"" en 59,2 procent ervoer ""seksuele angsten.""","Second, the associations identified in this study between self-reported symptoms and relationship variables are based on retrospective patient recall and are vulnerable to memory biases inherent in this type of data. Third, the SIAB was not designed specifically to measure sexual functioning and therefore, these results are considered to be preliminary and motivational for future studies to use instruments designed to assess relationship and sexual functioning. The SIAB questions do not have the sufficient specificity to determine when these variables occurred relative to the eating disorder symptoms.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=39444755850&p=1pl&v=1&x=NtCD7LA_1LPXSmdnpRmOQw
10.1016/j.tics.2013.02.007,Psychology_597,"Music Reduces Stress & Eases Anxiety

In today's day and age, the stress emphasized on employees and even students to succeed is tremendous!","Suitable pleasurable conditions would need to be administered as comparisons, for example, food pleasure.","I'll do an article on the songs that pushes me to go pass my limits on another day, so stay tuned for that. Music Reduces Stress & Eases Anxiety

In today's day and age, the stress emphasized on employees and even students to succeed is tremendous! Work has to be completed as soon as possible, sales targets have to be met, exams have to be aced with flying colors.","Here, it will be important for control tasks to include an equal amount of experimenter-participant interactions, as well as a stimulus that is wellcontrolled for similar arousal properties and emotional qualities. Suitable pleasurable conditions would need to be administered as comparisons, for example, food pleasure. Other exciting avenues for future research include investigations into the contribution of stress hormones, vasopressin, dopamine, and opioids using biological assays (e.g., blood serum, saliva, urine), and pharmacological interventions with neuroimaging techniques.","[3.0, 1.0, 3.0, 2.0]",Psychology,train,2.25,news,http://ct.moreover.com/?a=39894755952&p=1pl&v=1&x=SLmeG8ihLs3g4SDDig8zIQ
10.1073/pnas.1221880110,Psychology_598,"This difference completely changes the organization of the brain and therefore can create symptoms suggestive of autism like repetitive behaviors, the need to have orderly spaces, as well as social awkwardness.","S4) , if the MSD of a point is high, then that point is relatively more isolated (i.e., in a low-density environment) compared with a point with a low MSD (i.e., in a high-density environment).","Therefore, connections between brain cells in adulthood are shorter than those without ASD. This difference completely changes the organization of the brain and therefore can create symptoms suggestive of autism like repetitive behaviors, the need to have orderly spaces, as well as social awkwardness. Researchers found that shortened connections mostly occurred in the fronto-temporal region and cortico-cortical circuits of the brain.","Theoretically (Fig. S4) , if the MSD of a point is high, then that point is relatively more isolated (i.e., in a low-density environment) compared with a point with a low MSD (i.e., in a high-density environment). Thus, comparing MSD distributions across groups may reveal regions that have relatively greater or lesser density of underlying ""surface units.""","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.medicaldaily.com/articles/17651/20130722/autism-brain-grey-matter-autism-spectrum-disorder-brain-connectivity.htm
10.1007/s10803-014-2168-9,Psychology_599,"While children in both groups made progress, those receiving ESDM showed significantly higher gains in language (20 DQ points versus 10 in the control group) and cognition (14 DQ points, versus 7 in the control group).",Effectiveness and feasibility of the early start denver model implemented in a groupbased community childcare setting.,"While children in both groups made progress, those receiving ESDM showed significantly higher gains in language (20 DQ points versus 10 in the control group) and cognition (14 DQ points, versus 7 in the control group). There was variability in the gains made by children receiving the ESDM, with children who had more spontaneous imitation, functional play and joint attention skills showing the most sizeable cognitive gains. This study indicates that even with the adaptations of delivering the program in a childcare group environment instead of intensive individual home-based treatment, the ESDM has positive effects on development of young children with ASD.","Effectiveness and feasibility of the early start denver model implemented in a groupbased community childcare setting. Teaching episodes are embedded within the framework of naturalistic and intrinsically rewarding joint activities built on the child's spontaneous interests and motivation. Evidence for the efficacy of the ESDM is documented in an RCT ) indicating significant gains in cognitive, language, and adaptive abilities in a group of preschoolers with ASD receiving 15 h per week of individual home-based treatment over 2 years, as well as 4 h per month of individual parent coaching.","[4.0, 2.0, 4.0, 1.0]",Psychology,train,4.0,news,http://www.healthcanal.com/child-health/52542-learning-gains-for-autistic-children.html
10.1016/j.jpeds.2017.10.028,Psychology_6,The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood.,"The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","About 19 percent said they had committed some form of dating violence and 69 percent said they were physically punished during childhood. The study identified a significant association between corporal punishment during childhood and violence toward dating partners in adulthood. Specifically, people who got spanked as kids had a 29 percent higher risk for perpetrating dating violence, the findings showed.","Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment. (J Pediatr 2018;194:233-7).","[3.0, 4.0, 2.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1186/s13229-018-0246-0,Psychology_60,"In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","Second, we report autism prevalence in mainstream schools only in Shenzhen and Jiamusi cities.","In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","Most of the children identified in this study using these contemporary screening and diagnostic measures had not previously received an autism diagnosis, confirming underdiagnosis of autism in mainstream schools. Second, we report autism prevalence in mainstream schools only in Shenzhen and Jiamusi cities. Thus, the total score ranges from 0 to 31.","[4.0, 4.0, 2.0, 4.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1037/a0035601,Psychology_600,"Either way, noticing that your child is attracted to this literature ""may serve as a red flag for parents,"" he writes.","Banned books did not predict GPA, or commission of violent or nonviolent crimes.","It isn't clear from this data whether, for that troubled minority of teens, reading edgy fiction is cathartic and thus helpful, or if it leads to the sort of rumination that makes mental-health issues worse. Either way, noticing that your child is attracted to this literature ""may serve as a red flag for parents,"" he writes. That said, the study suggests that for the vast majority of kids, reading banned books does not seem to be harmful, and may even contribute to emotional and moral growth.","Banned books were associated with increased civic behaviors concurrently. Banned books did not predict GPA, or commission of violent or nonviolent crimes. However, banned books were associated with increased internalizing and externalizing mental health symptoms.","[1.0, 1.0, 2.0, 1.0, 1.0]",Psychology,train,1.2,news,http://www.psmag.com/navigation/books-and-culture/horrible-consequences-reading-banned-books-78715/
10.1016/j.biopsych.2014.05.018,Psychology_601,"advertisement

""This is not an extraordinary meal compared to what many of us would grab when we're in a hurry and out getting some food,"" said Kiecolt-Glaser, also director of the Institute for Behavioral Medicine at Ohio State.",Women with a depression history who also had more stressors had a higher peak triglyceride response than other participants (p ¼ .01).,"Most of the reported stressors were interpersonal in nature: arguments with co-workers or spouses, disagreements with friends, trouble with children or work-related pressures. advertisement

""This is not an extraordinary meal compared to what many of us would grab when we're in a hurry and out getting some food,"" said Kiecolt-Glaser, also director of the Institute for Behavioral Medicine at Ohio State. ""We suspected that the saturated fat would have a worse impact on metabolism in women, but in our findings, both high-fat meals consistently showed the same results in terms of how stressors could affect their energy expenditure,"" said Martha Belury, professor of human nutrition at Ohio State and a co-author of the study.","Women with prior MDD had higher cortisol (p ¼ .008) and higher fat oxidation (p ¼ .004), without significant effects for REE, insulin, and glucose. Women with a depression history who also had more stressors had a higher peak triglyceride response than other participants (p ¼ .01). The only difference between meals was higher postprandial glucose following sunflower oil compared with saturated fat (p ¼ .03).","[1.0, 3.0, 1.0, 1.0, 1.0]",Psychology,train,1.4,news,http://www.sciencedaily.com/releases/2014/07/140714100128.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1037/a0032282,Psychology_602,"While some people approach every new situation with a smile, others seem to thrive on disproval and uncompromising negativity.","If so, this would demonstrate that the dispositional attitude is an important and useful construct for attitudes research.","While some people approach every new situation with a smile, others seem to thrive on disproval and uncompromising negativity. By asserting that positive and negative dispositions actually precede outside stimuli, the findings may answer the age-old question why haters hate. Whereas people with positive dispositional attitudes have a natural inclination to like, or approve of, external objects and situations, those with negative dispositional attitudes exhibit a strong tendency to dislike them.","Dispositional attitudes should be positively related to traits concerning positive affect, negatively related to traits concerning negative affect, positively related to traits concerning curiosity, and unrelated to other traits. If so, this would demonstrate that the dispositional attitude is an important and useful construct for attitudes research. Dispositional attitudes should be measurable by having individuals evaluate a wide range of stimuli and then averaging across all evaluations for each individual.","[3.0, 4.0, 4.0, 1.0]",Psychology,train,1.0,news,http://www.medicaldaily.com/scientific-theory-haters-dispositional-attitudes-determine-negative-and-positive-responses-new-study
10.1086/511799,Psychology_603,"ADVERTISEMENT

Moments after she landed the gig, a cop arrested Browder for child abandonment.","This study offers a partial explanation for the mechanism behind a widespread, durable phenomenon with implications for a broad segment of the population.","Laura Browder is the latest example of how harsh America can be on working mothers. ADVERTISEMENT

Moments after she landed the gig, a cop arrested Browder for child abandonment. Though she was later released, the arrest was an unfriendly reminder of the tough calls moms often have to make.","Furthermore, the motherhood penalty appears to have remained stable over time . This study offers a partial explanation for the mechanism behind a widespread, durable phenomenon with implications for a broad segment of the population. While the magnitude of the gap decreased over much of this period , a sizeable gap remains, and the gap has not narrowed in recent years (Institute for Women's Policy Research 2006).","[1.0, 1.0, 1.0, 1.0, 2.0]",Psychology,train,1.2,news,http://www.rawstory.com/2015/07/america-leads-the-world-in-treating-working-moms-like-crap/
10.1177/0885412206295846,Psychology_605,"To understand how much better regulations have gotten on the issue of wait times, it helps to understand just how horrendous they were.","They call for an end to urinal troughs in men's restrooms, greater space between urinals, the construction of floor-to-ceiling partitions between urinals, and doors on all toilet stalls.","If most developers aren't going to install more toilets than are required by local or state plumbing codes, then perhaps the solution is to change the requirements. To understand how much better regulations have gotten on the issue of wait times, it helps to understand just how horrendous they were. ""From the outset,"" she explained, ""public toilet provision for women was seen as an extra, as a luxury, or as problematic in other respects.""","Soifer argued that some boys become targets for bullying-not perceived as being ""manly"" enough to stand up, show their equipment, and use a urinal-merely by entering a toilet cubicle. They call for an end to urinal troughs in men's restrooms, greater space between urinals, the construction of floor-to-ceiling partitions between urinals, and doors on all toilet stalls. Soifer also recommended a white noise device such as a fan to help users feel more comfortable.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=38330155006&p=1pl&v=1&x=yoRbmNGmzzRncA3u8TKYJw
10.1177/1948550614561126,Psychology_606,"""It is possible that women who are led to believe that men prefer women with bodies larger than the models depicted in the media may experience higher levels of self-esteem and lower levels of depression,"" Meltzer said.","First, although it conceptually replicated the findings of Study 1, Study 2 did not demonstrate the mechanism of the predicted effect.","They also tend to avoid unhealthy behaviors, such as excessive dieting and eating disorders, and they suffer less from depression. ""It is possible that women who are led to believe that men prefer women with bodies larger than the models depicted in the media may experience higher levels of self-esteem and lower levels of depression,"" Meltzer said. Women's weight satisfaction improved after image manipulation exercise

In all three studies, female participants viewed images of female models with bodies larger than the thin-ideal wearing a variety of clothing, ranging from typical street clothes to bathing suits.","Nevertheless, Study 2 has two important limitations. First, although it conceptually replicated the findings of Study 1, Study 2 did not demonstrate the mechanism of the predicted effect. Because women often believe that men prefer ultra-thin women (as suggested by the similar findings across Study 2's two control conditions), they likely place higher importance on obtaining a thin body and thus experience weight dissatisfaction.","[4.0, 3.0, 2.0, 3.0, 1.0]",Psychology,train,2.6,news,http://www.sciencedaily.com/releases/2015/01/150113121202.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1007/s10919-013-0170-0,Psychology_607,"This does, however, open up another issue for skilled liars; they could use this technique to manipulate other people into believing what they are saying.","Third, the first two of the present studies showed the perception of others to be influenced by the hand-over-heart gesture, and by definition, self-perception processes cannot explain the perceptions of other persons.","The basis of these experiments just show that placing our hand over our hearts might compel us to behave more morally. This does, however, open up another issue for skilled liars; they could use this technique to manipulate other people into believing what they are saying. This is why Parzuchowski and Wojciszke warn that a simple gesture like this one should not be taken as a ""truth serum.""","For example, a great majority of the participants of one multi-sample study (N [ 800 including pupils, students, and employees), showed quite extreme estimates of their honesty and other moral traits , and extremity of ratings typically goes hand-in-hand with their subjective certainty. Third, the first two of the present studies showed the perception of others to be influenced by the hand-over-heart gesture, and by definition, self-perception processes cannot explain the perceptions of other persons. All of this suggests that self-perception processes do not provide a plausible explanation for the present data.","[2.0, 2.0, 5.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.medicaldaily.com/telling-truth-influenced-placing-hand-heart-and-it-also-makes-you-look-more-trustworthy-272854
10.1098/rspb.2017.1819,Psychology_609,"By the a70s, we liked mustaches and a lot of body hair, and in the a90s, we loved big butts.","Not only are physically strong men more likely than weaker men to prevail in direct agonistic contests over resources [ , but they are also better hunters , and perceived by others in their communities as more effective generators of collective benefits related to resource production , leadership , and coalitional defence .","This also changes with the times. By the a70s, we liked mustaches and a lot of body hair, and in the a90s, we loved big butts. Subscribe to Inverse on YouTube for more curiosity-sparking journalism.","Greater physical formidability likely promotes men's resource accrual via multiple pathways. Not only are physically strong men more likely than weaker men to prevail in direct agonistic contests over resources [ , but they are also better hunters , and perceived by others in their communities as more effective generators of collective benefits related to resource production , leadership , and coalitional defence . In total, these considerations suggest that physical formidability would have been a reliable positive predictor of men's ability to accrue resources that could be invested in ancestral women and offspring.","[1.0, 3.0, 2.0, 1.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=34464052860&p=1pl&v=1&x=EJjEksT9s22txYmDKvEwXw
10.1001/jamapsychiatry.2018.1941,Psychology_61,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,"Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality.","In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","The results show that both poor sleep quality and depressive problems are significantly positively correlated with functional connectivities involving the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the cingulate cortex, and the precuneus. Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality. Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant.","[3.0, 5.0, 4.0, 4.0, 4.0]",Psychology,train,4.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1177/0141076814565942,Psychology_63,"The study discovered that, regardless of their cultural background, circumcised boys could be at greater risk of developing the condition.","However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases.","The study discovered that, regardless of their cultural background, circumcised boys could be at greater risk of developing the condition. While these days, it is considered unacceptable medical practice to perform a circumcision without proper pain relief, none of the most common interventions used to reduce such pain is capable of completely eliminating it, the study authors said. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences,"" he added.","Among boys in Muslim families, risk of hyperkinetic disorder did not depend on the boys' foreskin status (HR ¼ 1.08; 95% CI: 0.77-1.52). However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases. Associations of ritual circumcision with risk of asthma were consistently negative, both in the 0-4 years (HR ¼ 0.91; 95% CI: 0.78-1.06) and the 5-9 years age interval (HR ¼ 1.16; 95% CI: 0.89-1.51), yielding an inconspicuous overall HR estimate (HR ¼ 0.96; 95% CI: 0.84-1.10) based on a total of 235 cases of asthma in circumcised boys versus 29,002 cases in intact boys.","[4.0, 3.0, 2.0, 2.0, 3.0]",Psychology,train,2.8,news,http://www.redorbit.com/news/health/1113311836/does-circumcision-increase-the-risk-of-autism-011115/
10.1007/s40519-017-0414-9,Psychology_64,"Almost two-thirds of the participants were female, and the average age of the group was around 31 years of age.","There were a total of 119 male (39.5%) and 182 (60.5%) female participants aged 18-75 years (mean ± -SD = 31.37 ± 12.55 years, and median age = 27 years).","According to the researchers, the apparent prevalence of eating disorders seen in musicians ""could be due to their increased levels of perfectionism"", and the findings could help doctors to look for warning signs among a subset of patients. Almost two-thirds of the participants were female, and the average age of the group was around 31 years of age. After analysing the questionnaire data, the researchers revealed almost one-third of the group (32.3%) reported having experienced an eating disorder, a higher proportion than the estimated 1.6 million adults thought to be affected in the UK.","Some questions were not answered by all 301 musicians; therefore, percentages were calculated using the total of musicians who had answered the particular question, not all the 301 musicians (see tables for more details). There were a total of 119 male (39.5%) and 182 (60.5%) female participants aged 18-75 years (mean ± -SD = 31.37 ± 12.55 years, and median age = 27 years). Regarding the music they perform or teach, musicians responded with: classical (85.8%), jazz (19.5%), pop (15.9%), rock (14.2%), folk (3.9%), rap (2.3%), metal (1.9%), world music (1.6%) and other (17.8%).","[3.0, 3.0, 4.0, 1.0]",Psychology,train,2.75,news,http://healthmedicinet.com/news/musicians-have-high-prevalence-of-eating-disorders-study-finds/
10.1001/jamapsychiatry.2018.1941,Psychology_65,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""",Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems.,"Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[4.0, 5.0, 2.0]",Psychology,train,4.0,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1177/0956797617692041,Psychology_66,The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving.,"The effect of bundling was magnified among the participants restricted to the self-service condition: 20.7% bought large drinks in the bundled condition, compared with 37.1% in the typical-portion condition, χ 2 (1, N = 179) = 5.72, p = .02.","The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means. The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving. However, it did not affect the further downstream behavior of consumption.","In fact, the result of a χ 2 test comparing only the bundled and typical-portion conditions, collapsed across serving style, was significant: Drink purchasers were 64.8% less likely to buy a large drink in the bundled condition than in the typical-portion condition (25.6% bought a large drink in the bundled condition, and 39.5% bought a large drink in the typical-portion condition), χ 2 (1, N = 362) = 7.90, p = .005. The effect of bundling was magnified among the participants restricted to the self-service condition: 20.7% bought large drinks in the bundled condition, compared with 37.1% in the typical-portion condition, χ 2 (1, N = 179) = 5.72, p = .02. The findings, directionally consistent with those for purchasing, revealed that the participants in the bundled condition consumed 5.6% fewer calories than those in the typicalportion condition; however, this difference did not reach statistical significance (typical portion: M = 122.61 kcal, SD = 47.92; bundled: M = 115.70 kcal, SD = 49.77), F(1, 358) = 1.67, p = .20.","[3.0, 4.0, 4.0]",Psychology,train,3.6666666666666665,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1001/jamapsychiatry.2018.1941,Psychology_67,"While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.",Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems.,"Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans. While anyone whoas experienced the difficulty of depression or insomnia may not be surprised that theyare connected, this study marks the first time scientists can definitively say there are neural mechanisms underlying the relationship between the two.",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[3.0, 3.0, 3.0, 2.0]",Psychology,train,2.75,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1001/jamapsychiatry.2018.1941,Psychology_68,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants.","Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","We note that the causal relations between sleep and depression is an important topic that deserves much further investigation. Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants. A strength of this investigation is that the effects are likely to be very robust, given the large sample of participants with resting-state fMRI and the cross-validation with the UK Biobank data set with a sample of 8718 participants in one of its first uses of resting-state fMRI data.","[2.0, 4.0, 2.0, 3.0, 3.0]",Psychology,train,2.8,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1001/jamapsychiatry.2018.1941,Psychology_69,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001). A total of 162 functional connectivity links involving areas associated with sleep, such as the precuneus, anterior cingulate cortex, and the lateral orbitofrontal cortex, were identified.","[2.0, 4.0, 3.0, 2.0, 4.0]",Psychology,train,3.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1177/0141076814565942,Psychology_70,They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD.,We confirmed our hypothesis that boys who undergo ritual circumcision may run a greater risk of developing ASD.,"They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","Associations with asthma were consistently inconspicuous (HR ¼ 0.96; 95% CI: 0.84-1.10). We confirmed our hypothesis that boys who undergo ritual circumcision may run a greater risk of developing ASD. This finding, and the unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families, need attention, particularly because data limitations most likely rendered our HR estimates conservative.","[4.0, 5.0, 4.0, 5.0]",Psychology,train,4.5,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1001/jamapsychiatry.2018.1941,Psychology_71,The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality.,"Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant.","In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion). The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.","Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality. Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","[2.0, 2.0, 3.0]",Psychology,train,2.333333333333333,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1073/pnas.1702671114,Psychology_72,Scientists had believed the Lombard effect was much slower: about 150 milliseconds for birds and bats and approximately150 to 175 milliseconds for humans.,The absolute differences between the model prediction and the data for these conditions were 0.6 ± 0.45 dB.,"When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization. Even in terms of near-instantaneous brain reactions, they call this reflex ""remarkably short."" Scientists had believed the Lombard effect was much slower: about 150 milliseconds for birds and bats and approximately150 to 175 milliseconds for humans.","4 C-J shows that the model accounts for the data from the other eight experimental conditions quite well. The absolute differences between the model prediction and the data for these conditions were 0.6 ± 0.45 dB. In other words, once the three parameters are established, the fine time course of the Lombard effect can be predicted precisely.","[4.0, 1.0, 2.0, 1.0, 1.0]",Psychology,train,1.8,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1007/s13524-014-0321-x,Psychology_73,"Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child.","However, the extent of bias resulting from cross-sectional analysis likely depends on the set of control variables that are available and used, and also the context.","Also, the likelihood of a pregnancy being unplanned may increase with the number of children a woman already has -- and this brings its own stresses."" Compared to men, women gain more in happiness in expectation of, and right after, the birth of a child. Women also have steeper drops in their happiness than men between the year of the birth and the year afterward, possibly because of the larger initial gain.","It is possible that unobserved confounding is a relatively small problem also in other cross-sectional research on subjective well-being and fertility. However, the extent of bias resulting from cross-sectional analysis likely depends on the set of control variables that are available and used, and also the context. One cannot infer from our results that the set of control variables used in our regressions would effectively control for selection in some other context.","[2.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.2,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_74,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems.,"The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.",IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[3.0, 1.0, 4.0, 4.0]",Psychology,train,4.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1186/s13229-018-0246-0,Psychology_75,"""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","By definition, they are not the children reported in previous prevalence studies of children with autism in China attending special education schools.","In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China. We have been able to use a standardized screening methodology, allowing us to compare the results with Western countries to show that autism occurs broadly at the same rate, irrespective of culture.""","Thus, the total score ranges from 0 to 31. By definition, they are not the children reported in previous prevalence studies of children with autism in China attending special education schools. Three cities met these criteria.","[2.0, 2.0, 2.0, 2.0]",Psychology,train,2.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1007/s13524-014-0321-x,Psychology_77,Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth.,"Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below.","Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Young parents have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below. Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline.","[2.0, 2.0, 2.0, 2.0]",Psychology,train,2.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1038/s41598-018-30980-y,Psychology_78,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","3B ) and positively predicted ΔRecall overnight (B = 0.518, p = 0.028; 95% CI: [0.000, 0.005]; Fig.","Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.","Supporting an interaction across sleep bouts, SWA in the nap negatively predicted ΔRecall nap (B = −0.601, p = 0.008; 95% CI: [−2.982, −0.517]; Fig. 3B ) and positively predicted ΔRecall overnight (B = 0.518, p = 0.028; 95% CI: [0.000, 0.005]; Fig. Importantly, ΔRecall overnight was also positively predicted by overnight SWS in the nap condition as previously stated; however, this relationship was not observed in the wake condition (B = 0.140, p = 0.606; Fig.","[4.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1001/jamapsychiatry.2018.1941,Psychology_79,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,"Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus. 35 These findings support the theory that the nonreward system in the lateral orbitofrontal cortex has increased influence on areas in which the self is represented, which results in low self-esteem, with the increased connectivity to the prefrontal cortex short-term memory system contributing to the rumination symptoms characteristic of depression.","[4.0, 3.0, 3.0, 4.0]",Psychology,train,3.5,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1038/s41598-018-30980-y,Psychology_8,Yet nap slow wave activity also predicted greater overnight improvement in memory.,Greater nap slow wave activity was associated with greater memory decay during the nap.,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory. Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","[2.0, 1.0, 3.0, 4.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1111/cdep.12038,Psychology_80,"Spanking Runs In The Family

Researchers also found that the more children are spanked, the more likely they were to use physical punishment to discipline their own children.","Spanking consistently predicted increases in children's aggression over time, regardless of how aggressive children were when the spanking occurred.","""This shows there is a correlation between spanking and negative outcomes and absolutely no correlation between spanking and positive outcomes."" Spanking Runs In The Family

Researchers also found that the more children are spanked, the more likely they were to use physical punishment to discipline their own children. This goes to show that the culture of violence is passed down from generation to generation.","Rather, spanking predicted increases in children's aggression over and above initial levels. Spanking consistently predicted increases in children's aggression over time, regardless of how aggressive children were when the spanking occurred. It is difficult to imagine that a parent would be able to meet all these criteria when administering spanking; indeed, it would likely be both inadvisable and bordering on abusive if parents spanked children following every instance of a given misbehavior.","[4.0, 4.0, 3.0]",Psychology,train,3.6666666666666665,news,http://www.parentherald.com/articles/39890/20160428/okay-spank-children-5-decade-research.htm
10.1111/cdev.12250,Psychology_81,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""",One potential explanation for these findings is provided by cumulative continuity theory .,"By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","In terms of competence with peers, pseudomature behavior in early adolescence predicted not only declining popularity with peers across adolescence but also lower levels of peer competence, as rated by peers, in early adulthood. One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","[1.0, 1.0, 1.0]",Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1093/jcr/ucw012,Psychology_82,One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.,"Specifically, we show that mere receipt of a behaviorally targeted ad can cause consumers to recognize that the marketer has labeled them as a particular type of consumer, even when the ad itself contains no descriptive information about the individual consumer.","For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.","In addition, our work contributes to the literature on social labeling by introducing a new type of implied social label. Specifically, we show that mere receipt of a behaviorally targeted ad can cause consumers to recognize that the marketer has labeled them as a particular type of consumer, even when the ad itself contains no descriptive information about the individual consumer. In doing so, we contribute to the literature by demonstrating that labels do not have to reference the consumer to have an effect (as has been shown in past research), but that consumers can be affected by implied labels supplied by external sources.","[3.0, 2.0, 2.0, 3.0]",Psychology,train,2.5,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1093/jcr/ucw012,Psychology_83,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","However, if a consumer concludes that marketers are purposefully using behaviorally targeted ads as implied social labels to change their self-perceptions, the consumer could react against the attempt, minimizing its effectiveness .","""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.","As discussed, some level of marketplace metacognition is required for a behaviorally targeted ad to serve as a social label. However, if a consumer concludes that marketers are purposefully using behaviorally targeted ads as implied social labels to change their self-perceptions, the consumer could react against the attempt, minimizing its effectiveness . Exploring whether implied social labels from marketers induce the same level of persuasion knowledge as explicit social labels from marketers ) could be worthwhile.","[4.0, 2.0, 1.0, 3.0]",Psychology,train,2.5,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jpeds.2017.10.028,Psychology_85,There was a positive relationship between corporal punishment and physical violence during a romantic relationship.,"Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59).","In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship. Lead study researcher Jeff Temple PhD, an associate professor at the University of Texas who specializes in dating violence, told Newsweek that one unit increase in corporal punished was associated with a 29 percent increase in perpetrating dating violence.","Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","[5.0, 5.0, 4.0, 5.0, 4.0]",Psychology,train,4.6,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1093/jcr/ucw012,Psychology_86,"When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer.","Specifically, consumers receiving a behaviorally targeted ad for an environmentally friendly ""green"" product viewed themselves as possessing stronger green consumption values.","""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said. When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer. Those are the types of labels that can change people's views about themselves.","The results of study 3 replicate previous results by showing that ads identified as behaviorally targeted can affect consumer self-perceptions and hence behavior. Specifically, consumers receiving a behaviorally targeted ad for an environmentally friendly ""green"" product viewed themselves as possessing stronger green consumption values. These increased self-perceptions of greenness mediated their willingness to purchase the advertised product and the amount they wished to donate to an environmental charity.","[4.0, 2.0, 2.0, 4.0]",Psychology,train,3.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1007/s13524-014-0321-x,Psychology_87,The happiness level of parents varied among different ages.,"Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline.","On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.","Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below. Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline. A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain.","[1.0, 3.0, 1.0, 2.0, 5.0]",Psychology,train,2.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1016/j.jpeds.2017.10.028,Psychology_89,"In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children.","The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","Of the 758 young adults recruited for the study, 61 percent were female. In total,19 percent of the young volunteers involved in the study reported that they had been physically abusive to a partner during a dating relationship and 68 percent of the volunteers reported to experiencing corporal punishment as children. There was a positive relationship between corporal punishment and physical violence during a romantic relationship.","Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment. (J Pediatr 2018;194:233-7).","[4.0, 3.0, 4.0, 3.0]",Psychology,train,3.5,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1177/0141076814565942,Psychology_9,The researchers say that the pain associated with circumcision in very young babies is likely to be more severe during the operation and post-operatively.,"5 The procedural pain associated with neonatal circumcision is plausibly more severe and the postoperative pain of longer duration than in older children and adults, because the foreskin of most neonates must be forcefully separated from the glans to which it is fused before it can be cut off.","Risk was particularly high for infantile autism before the age of five, at least in epidemiology. The researchers say that the pain associated with circumcision in very young babies is likely to be more severe during the operation and post-operatively. ""Given the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, our findings should prompt other researchers to examine the possibility that circumcision trauma in infancy or early childhood might carry an increased risk of serious neurodevelopmental and psychological consequences.""",", , 4 Regardless of surgical method, circumcision causes some level of pain and discomfort at the operation table and for several days after until wound healing has completed. 5 The procedural pain associated with neonatal circumcision is plausibly more severe and the postoperative pain of longer duration than in older children and adults, because the foreskin of most neonates must be forcefully separated from the glans to which it is fused before it can be cut off. Older children whose foreskins have already spontaneously separated from the glans will only experience the pain associated with the foreskin incision.","[3.0, 4.0, 5.0, 4.0]",Psychology,train,4.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1111/cdev.12250,Psychology_90,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Even almost a decade later, however, social status concerns continued to play a key role in the lives of these individuals as adults, as they found themselves more likely to perceive that their romantic partners were ending relationships with them based upon their own lack of social status.","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Indeed, it is possible that this fading popularity advantage may be what leads these adolescents to pursue more and more extreme behaviors in an effort to attain status with at least a subset of their peers, although this explanation remains for future research to examine. Even almost a decade later, however, social status concerns continued to play a key role in the lives of these individuals as adults, as they found themselves more likely to perceive that their romantic partners were ending relationships with them based upon their own lack of social status. One explanation for this long-term link is that teens who engage in high levels of pseudomature behavior have set themselves on a path in which they place an outsized role on the importance of social status in relationships.","[4.0, 2.0, 2.0, 3.0, 1.0]",Psychology,train,2.4,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1016/j.jpeds.2017.10.028,Psychology_91,"""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult.""","There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","That held true even after the researchers took into account the person's age, gender, parents' education and any history of child physical abuse. ""The current study adds to this knowledge by showing that being physically punished as a child is linked to perpetrating dating violence as a teen and young adult."" It's not that big a stretch to connect the two, he added.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[2.0, 2.0, 1.0, 2.0]",Psychology,train,1.75,news,http://ct.moreover.com/?a=32686504555&p=1pl&v=1&x=J_KXigEKTcXYUPzjI0fyuQ
10.1038/s41598-017-03627-7,Psychology_92,Further research is necessary to figure out precisely how a partner's touch eases pain.,"As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect.","""It could be that touch is a tool for communicating empathy, resulting in an analgesic, or pain-killing, effect,"" said Goldstein. Further research is necessary to figure out precisely how a partner's touch eases pain. The study did not explore whether the same effect would occur with same-sex couples, or what happens when the man is the subject of pain.","Physiologically, interpersonal touch increases the coupling of electrodermal activity and pulse rate variability 35 and modulates blood pressure reactivity to stress 36 as well as reactivity to distress 37 . As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect. In addition, during the pain-alone condition, the women's pain ratings were marginally higher than in the partner-no touch condition (M diff = 0.29, p = 0.093).","[2.0, 5.0, 2.0, 4.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1093/jcr/ucw012,Psychology_93,One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.,The results of study 3 replicate previous results by showing that ads identified as behaviorally targeted can affect consumer self-perceptions and hence behavior.,"For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate. ""The ad has to be plausible to the consumer for it have any effect,"" Reczek said.",", and this effect was not present when the order of the mediators was reversed (b ¼ .0046, SE ¼ .02, 95% CI, À.0297 to .0607). The results of study 3 replicate previous results by showing that ads identified as behaviorally targeted can affect consumer self-perceptions and hence behavior. Specifically, consumers receiving a behaviorally targeted ad for an environmentally friendly ""green"" product viewed themselves as possessing stronger green consumption values.","[4.0, 2.0, 1.0, 2.0, 2.0]",Psychology,train,2.2,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1001/jamapsychiatry.2018.1941,Psychology_94,"""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis.","Researchers believe it is the first time the neural mechanisms underlying the association of depression and sleep have been studied in a large sample. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified."" ""This study may also have implications for a deeper understanding of depression,"" he said.","We note that there is a strong association between depression and poor sleep, in that the correlation found in this study between the Depressive Problems score and PSQI score was high (r = 0.371, P <1.0×10 −10 , Figure 1B) ; however, this does not address the directionality of the association, which could be in both directions. Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis. We note that the causal relations between sleep and depression is an important topic that deserves much further investigation.","[3.0, 3.0, 3.0]",Psychology,train,3.0,news,http://ct.moreover.com/?a=34634204738&p=1pl&v=1&x=GZ7D3xt9Fp7_9IgR9S1Qrg
10.1093/schbul/sbv109,Psychology_95,"###

The paper aEURoeA Neuroanatomical Signature for Schizophrenia Across Different Ethnic GroupsaEUR can be accessed here: http://schizophreniabulletin.oxfordjournals.org/content/early/2015/08/10/schbul.sbv109.full?sid=a9367e61-bbdf-4a49-9772-cd42ee6cb619

Note to Reporters:

Any mention or reporting of data from this article should be attributed to: Schizophrenia Bulletin, published by Oxford University Press, seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia.",This would provide evidence for a neuroanatomical signature of schizophrenia expressed above and beyond ethnic differences in incidence and clinical expression.,"Their work provides additional evidence that this region may provide valuable information that could be used to inform diagnostic evaluations in not only schizophrenia but other Axis I disorders such as bipolar disorder, depression, addiction, obsessive-compulsive disorder and anxiety regardless of ethnicity. ###

The paper aEURoeA Neuroanatomical Signature for Schizophrenia Across Different Ethnic GroupsaEUR can be accessed here: http://schizophreniabulletin.oxfordjournals.org/content/early/2015/08/10/schbul.sbv109.full?sid=a9367e61-bbdf-4a49-9772-cd42ee6cb619

Note to Reporters:

Any mention or reporting of data from this article should be attributed to: Schizophrenia Bulletin, published by Oxford University Press, seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia. Media queries and interview requests should be directed to:

Department of Psychosis Studies, Institute of Psychiatry, Psychology Neuroscience, KingaEUR(tm)s College London, London SE5 8AF, UK; tel: +44 (0)20 7848 0289, e-mail: a.mechelli@kcl.ac.uk","As the 4 groups were scanned at different sites using different scanners and acquisition sequences (see supplementary table S1 for detail), any discrepancy between datasets could be due to methodological differences. This would provide evidence for a neuroanatomical signature of schizophrenia expressed above and beyond ethnic differences in incidence and clinical expression. All patients in the Chinese sample were medication naïve at the time of scanning; in contrast, patients in the White Caucasian, African-Caribbean and Japanese samples were taking first-or second-generation antipsychotic medication, or a combination of the two (see table 1 for chlorpromazineequivalent dose).","[1.0, 2.0, 2.0, 1.0, 2.0]",Psychology,train,1.6,news,http://healthmedicinet.com/news/researchers-find-neuroanatomical-signature-for-schizophrenia/
10.1136/bmjsem-2017-000261,Psychology_97,"Also, notably, they only noticed statistically significant spikes in the saliva cortisol levels of male athletes, which the authors admit requires further investigation.",The results of this meta-analysis identify that athletes who anticipate to compete in a sport competition have a significant anticipatory salivary cortisol response.,"They found that there was a asignificant anticipatory cortisol response before competition,a although the spikes werenat as strong as those seen before other intense events, like skydiving. Also, notably, they only noticed statistically significant spikes in the saliva cortisol levels of male athletes, which the authors admit requires further investigation. Their research highlights the idea that just the idea of impending doom can be enough to flood your body with enough of the stress hormones that serve to raise heart rate.",These factors can positively skew the concentration of salivary cortisol. The results of this meta-analysis identify that athletes who anticipate to compete in a sport competition have a significant anticipatory salivary cortisol response. Female athletes and athletes competing at international level do not demonstrate this significant anticipatory cortisol response.,"[4.0, 2.0, 4.0, 3.0]",Psychology,train,3.25,news,http://ct.moreover.com/?a=34474732617&p=1pl&v=1&x=pcdQFFmMveKF7UrJyJtzvg
10.1111/cdev.12250,Psychology_98,"The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote.","The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.","In fact, just the opposite happened. The pseudomature behaviors evolved into larger problems and the status of once cool individuals dropped: ""The adolescent who comes to depend upon pseudomature behavior to gain peer status may gradually need to shift, for example, from minor forms of delinquency, such as vandalism and shoplifting, to more serious acts of criminal behavior to impress even a subset of older peers,"" the authors wrote. The chart below shows that students who engaged in pseudomature behavior at 13 were perceived as more popular by their peers than those who did not engage in pseudomature behavior, but that correlation faded over time.","This study found that a constellation of pseudomature behaviors in early adolescence predicted significant difficulties in social functioning up to 10 years later, in early adulthood. The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence. The early adolescent behaviors examined-minor forms of delinquency, early romantic behavior, and a focus on physical appearance in seeking out friends-are often considered to be nearly normative and only modestly problematic aspects of adolescence, and are widespread by mid-adolescence ; however, when they appear early in adolescence, these seemingly minor Criminal behavior (ages 21-23)","[3.0, 3.0, 2.0, 4.0]",Psychology,train,3.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1073/pnas.1505114112,Psychology_99,The findings suggest that music instruction helps enhance skills that are critical for academic success.,"The music training group also exhibited earlier emergence of the adult cortical response, suggesting that in-school music accelerates neurodevelopment.","(EaglebrookSchool/CC BY 2.0)

Band Class Helps Teens Learn How to Learn

Music training, introduced as late as high school, may help improve how a teenager's brain responds to sound and could sharpen their hearing and language skills, too. The findings suggest that music instruction helps enhance skills that are critical for academic success. The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment.","Relative to an active control group that shows the expected wane in subcortical response consistency, adolescents undertaking in-school music training maintained heightened neural consistency throughout high school. The music training group also exhibited earlier emergence of the adult cortical response, suggesting that in-school music accelerates neurodevelopment. These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls.","[4.0, 4.0, 2.0, 2.0, 4.0]",Psychology,train,3.2,news,http://www.theepochtimes.com/n3/1677179-band-class-helps-teens-learn-how-learn/
10.1016/j.jpeds.2017.10.028,Psychology_tweet_1,"""Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration."" #iseeDV ","Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","""Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration."" #iseeDV ","Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","[5.0, 4.0, 5.0, 5.0]",Psychology,train,4.75,tweets,939146062534709254
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_10,Study reveals the link between poor #sleep and depression. ,"Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality.",Study reveals the link between poor #sleep and depression. ,"The results show that both poor sleep quality and depressive problems are significantly positively correlated with functional connectivities involving the lateral orbitofrontal cortex, the dorsolateral prefrontal cortex, the cingulate cortex, and the precuneus. Further, a mediation analysis showed that the functional connectivity links between the brain areas identified played a significant role in the association of depressive problems with poor sleep quality. Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant.","[5.0, 4.0, 5.0, 4.0, 4.0]",Psychology,train,4.4,tweets,1026502454345703424
10.1073/pnas.1813588116,Psychology_tweet_100,"How mindfulness reduces loneliness

Short-term study of 153 adults who completed #smartphone-based stress management interventions found that a combination of awareness &amp; acceptance training-core elements of #mindfulness #meditation--was the most successful","Although this study carefully controlled for nonspecific intervention factors, acceptance training may build on several of these contextual features.","How mindfulness reduces loneliness

Short-term study of 153 adults who completed #smartphone-based stress management interventions found that a combination of awareness &amp; acceptance training-core elements of #mindfulness #meditation--was the most successful","In hopes of guiding further research that builds on the present findings, we highlight several considerations about the study design and interventions that may prove important for replication and extension. Although this study carefully controlled for nonspecific intervention factors, acceptance training may build on several of these contextual features. First, it is important to reiterate that monitoring and acceptance-rather than acceptance alone-act synergistically to reduce social risk factors.","[5.0, 1.0, 2.0, 3.0, 2.0]",Psychology,train,2.0,tweets,1095059946243264513
10.1001/jamapsychiatry.2018.2028,Psychology_tweet_101,Is #PTSD associated with incident type 2 #diabetes independent of #obesity? Find out  #T2D,"After adjusting for age, the cumulative incidence of T2DM was significantly higher in those with PTSD vs those without (patients with PTSD: 6.6%; patients without PTSD: 4.7%; P = .002); the same pattern occurred with respect to incidence rate (patients with PTSD: 15.2 per 1000 person-years; patients without PTSD: 11.4 per 1000 person-years; P = .01).",Is #PTSD associated with incident type 2 #diabetes independent of #obesity? Find out  #T2D,"Prior to adjusting for age, the T2DM cumulative incidence percent and incidence rates were similar in patients with PTSD (252 [7.3%]) and without PTSD (141 [6.4%]; P = .19). After adjusting for age, the cumulative incidence of T2DM was significantly higher in those with PTSD vs those without (patients with PTSD: 6.6%; patients without PTSD: 4.7%; P = .002); the same pattern occurred with respect to incidence rate (patients with PTSD: 15.2 per 1000 person-years; patients without PTSD: 11.4 per 1000 person-years; P = .01). After adjusting for age in model 2, PTSD was associated with a 33% increased likelihood of incident T2DM (hazard ratio [HR], 1.33; 95% CI, 1.08-1.64; P = .01).","[2.0, 3.0, 3.0, 4.0, 1.0]",Psychology,train,2.6,tweets,1027524902398685185
10.1073/pnas.1409643111,Psychology_tweet_103,PNAS paper. - masculinised &amp; feminised faces appeal more to urbanites than non urbanites ,"Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization.",PNAS paper. - masculinised &amp; feminised faces appeal more to urbanites than non urbanites ,"Surprisingly, preferences for exaggerated sex-specific traits are only found in the novel, highly developed environments. Similarly, perceptions that masculine males look aggressive increase strongly with development and, specifically, urbanization. These data challenge the hypothesis that facial dimorphism was an important ancestral signal of heritable mate value.","[1.0, 2.0, 2.0, 3.0, 3.0]",Psychology,train,2.2,tweets,514344831280513024
10.1016/j.bodyim.2016.09.005,Psychology_tweet_104,"latest article: Could Barbie lead to greater thin-ideal internalisation?
","However, the results of the study did not support these conjectures as the different types of Barbie exposure produced no significant differences in thin-ideal internalisation, body esteem, or body dissatisfaction scores.","latest article: Could Barbie lead to greater thin-ideal internalisation?
","Such research could also provide insight into the reason results differed from those of . However, the results of the study did not support these conjectures as the different types of Barbie exposure produced no significant differences in thin-ideal internalisation, body esteem, or body dissatisfaction scores. It is possible that girls in this age group may already be so familiar with Barbie's figure from previous experience that any exposure to Barbie triggers associations with previous exposure (in print, observation, or active play) and elicits Barbie's thin-ideal messages.","[4.0, 4.0, 1.0, 2.0, 4.0]",Psychology,train,3.0,tweets,782796190685335552
10.1177/1948550616644299,Psychology_tweet_105,"Photo-Narcissm: Selfie-takers overrate the positive attributes
purveyed by their selfies.  ","Thus, selfie-takers departed further from the external raters' objective perceptions of attractiveness than the non-selfie-takers did but only for impressions of their selfies (see Figure 1) .","Photo-Narcissm: Selfie-takers overrate the positive attributes
purveyed by their selfies.  ","This showed that the differences between the self-and others' ratings of selfies were significantly greater for selfie- .38 ], but that the differences between the selfie-takers (M ¼ 0.83, SD ¼ 1.66) and nonselfie-takers (M ¼ 0.51, SD ¼ 1.53) were about the same for the experimenter-taken photos, t(196) ¼ 1.40, p ¼ .16, r p ¼ .10, 95% CI [À.04, .24]. Thus, selfie-takers departed further from the external raters' objective perceptions of attractiveness than the non-selfie-takers did but only for impressions of their selfies (see Figure 1) . Analyzing the data separately for the targets' selfratings, we observed a significant main effect of Group, [.01, .29] , suggesting that selfie-takers and non-selfie-takers rated the attractiveness of their selfies and experimenter-taken photos differently.","[4.0, 2.0, 3.0, 4.0, 4.0]",Psychology,train,3.4,tweets,725915407421329409
10.1177/0956797614533968,Psychology_tweet_106,"When dads do housework, their daughters are more likely to seek careers outside the home.  #PW",Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences.,"When dads do housework, their daughters are more likely to seek careers outside the home.  #PW","In addition, when fathers enacted or espoused a more egalitarian distribution of household labor, their daughters in particular expressed a greater interest in working outside the home and having a less stereotypical occupation. Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences. These findings suggest that a more balanced division of household labor between parents might promote greater workforce equality in future generations.","[3.0, 5.0, 5.0, 3.0]",Psychology,train,4.0,tweets,473822034905284608
10.1080/14649365.2013.862846,Psychology_tweet_107,Discover seismologies of emotion in this free article: fear and activism during domestic violence ,But the eradication of fear requires wider social responsibility for violence.,Discover seismologies of emotion in this free article: fear and activism during domestic violence ,"Fear is never simply about one's immediate situation, then, but is relational; emotions felt in an intimate setting may be reinforced or alleviated by actions at other scales. But the eradication of fear requires wider social responsibility for violence. Cheryl: I feel more confident now...about life as well…I'm proud of myself like how far I've came and like that I done it on my own.","[3.0, 2.0, 3.0, 2.0]",Psychology,train,2.5,tweets,445502348862164993
10.1073/pnas.1603865113,Psychology_tweet_108,Slow-motion replays can distort jurors' perception of criminal responsibility  ,We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception.,Slow-motion replays can distort jurors' perception of criminal responsibility  ,"Four additional experiments (n = 2,737) reveal that allowing viewers to see both regular speed and slow motion replay mitigates the bias, but does not eliminate it. We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception. This slow motion intentionality bias occurred, in part, because slow motion video caused participants to feel like the actor had more time to act, even when they knew how much clock time had actually elapsed.","[4.0, 4.0, 3.0, 4.0]",Psychology,train,3.75,tweets,760370453097635840
10.1016/j.cub.2009.09.064,Psychology_tweet_109,"Newborns cry in the mother's accent, which they learnt in the womb #wowza  paper: ",Adult-like processing of pitch intervals allows newborns to appreciate musical melodies and emotional and linguistic prosody .,"Newborns cry in the mother's accent, which they learnt in the womb #wowza  paper: ","Adult-like processing of pitch intervals allows newborns to appreciate musical melodies and emotional and linguistic prosody . Although prenatal exposure to native-language prosody influences newborns' perception, the surrounding language affects sound production apparently much later . The French group preferentially produced cries with a rising melody contour, whereas the German group preferentially produced falling contours.","[2.0, 3.0, 3.0]",Psychology,train,2.6666666666666665,tweets,142281378665467904
10.1093/geronb/gbx092,Psychology_tweet_11,Older adults who were widowed who volunteered about 100 hours a year reduced their risk of loneliness to those who were married. Results suggest having new social networks can notably reduce the risk of loneliness among people who are widowed. ,"Despite these limitations, the results from this study provide encouraging support for the potential of volunteer engagement as an intervention for alleviating loneliness among widows.",Older adults who were widowed who volunteered about 100 hours a year reduced their risk of loneliness to those who were married. Results suggest having new social networks can notably reduce the risk of loneliness among people who are widowed. ,"Although the goals of this study focus on whether starting a new volunteering role relates to lower levels of loneliness following widowhood regardless of previous volunteer history, future research might examine transitions into and out of volunteer work, its co-occurrence with caregiving and its effect on loneliness to determine if these effects vary based on history of volunteer engagement. Despite these limitations, the results from this study provide encouraging support for the potential of volunteer engagement as an intervention for alleviating loneliness among widows. In addition, given the numerous benefits associated with engaging in volunteering in general, and with 2 hr or more per week in particular , individuals who start a new volunteer role and continue to remain engaged over an extended period may experience health and well-being benefits that facilitate more successful aging.","[4.0, 5.0, 3.0, 4.0, 4.0]",Psychology,train,4.0,tweets,986341809562570753
10.3109/17483107.2014.981874,Psychology_tweet_110,#Stroke survivors can have “significant” improvement in arm movements after using interactive video games ,The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist .,#Stroke survivors can have “significant” improvement in arm movements after using interactive video games ,"A perceived lack of support from physiotherapists was the most frequently mentioned factor associated with lack of compliance. The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist . Firstly, a comprehensive review of the literature is presented to foreground the development work that is the focus of this paper.","[4.0, 4.0, 3.0, 5.0]",Psychology,train,4.0,tweets,542275051790565376
10.1038/npp.2011.6,Psychology_tweet_111,"""Pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech... ","The placebo group presented higher anxiety, cognitive impairment, discomfort, and alert levels when compared with the control group as assessed with the VAMS.","""Pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech... ","Pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alert in their anticipatory speech. The placebo group presented higher anxiety, cognitive impairment, discomfort, and alert levels when compared with the control group as assessed with the VAMS. The SSPS-N scores evidenced significant increases during the testing of placebo group that was almost abolished in the CBD group.","[1.0, 5.0, 4.0, 3.0, 1.0]",Psychology,train,4.0,tweets,239855864532574210
10.1007/s11121-013-0411-9,Psychology_tweet_112,"#Binge Eating May Signal #Anxiety, #Depression &amp; #Suicide Risk in African-American girls: Prevention Science: ","In addition to high levels of internalizing problems, adolescents with binge-eating disorder also had high levels of suicide attempt and ideation.","#Binge Eating May Signal #Anxiety, #Depression &amp; #Suicide Risk in African-American girls: Prevention Science: ","These results, along with those found with the present study, add credence to the idea of developing a universal prevention program aimed at lessening the incidence of binge eating along with a more individualized program targeted toward those at highest risk for internalizing problems along with binge-eating problems. In addition to high levels of internalizing problems, adolescents with binge-eating disorder also had high levels of suicide attempt and ideation. A possible explanation for these results is that the binge-eating problems are simply a way for individuals to cope with and manage their internalizing issues.","[3.0, 1.0, 4.0, 5.0, 4.0]",Psychology,train,4.0,tweets,360017534646353921
10.1037/a0032282,Psychology_tweet_113,"Hepler, J., &amp; Albarracin, D. (2013). Attitudes without objects: Evidence for a dispositional attitude, its... ","If so, this would demonstrate that the dispositional attitude is an important and useful construct for attitudes research.","Hepler, J., &amp; Albarracin, D. (2013). Attitudes without objects: Evidence for a dispositional attitude, its... ","Dispositional attitudes should be positively related to traits concerning positive affect, negatively related to traits concerning negative affect, positively related to traits concerning curiosity, and unrelated to other traits. If so, this would demonstrate that the dispositional attitude is an important and useful construct for attitudes research. Dispositional attitudes should be measurable by having individuals evaluate a wide range of stimuli and then averaging across all evaluations for each individual.","[1.0, 4.0, 4.0, 2.0]",Psychology,train,2.0,tweets,372406364418875392
10.1111/acer.12524,Psychology_tweet_114,Binge drinking negates protective gene for adolscents:   #alcohol #adolescenthealth,"This specific example of a genetic variant that influences early drinking milestones, but not initiation, builds on twin and adoption study findings that genetic factors contribute to the development of adolescent alcohol-related problems, and environmental factors more strongly drive drinking initiation .",Binge drinking negates protective gene for adolscents:   #alcohol #adolescenthealth,"Despite having an early role in the trajectory of drinking behaviors, the ADH1B variant was not associated with drinking initiation, consistent with the hypothesized mechanism of action that requires alcohol exposure . This specific example of a genetic variant that influences early drinking milestones, but not initiation, builds on twin and adoption study findings that genetic factors contribute to the development of adolescent alcohol-related problems, and environmental factors more strongly drive drinking initiation . Beyond demonstrating an early protective role of the ADH1B GA/AA genotypes in the development of these drinking behaviors, the results illustrate that reporting most or all best friends drinking was associated with attenuation of this genetic protection (Fig.","[3.0, 2.0, 2.0, 3.0, 4.0]",Psychology,train,2.8,tweets,514990133389455362
10.1111/cdep.12038,Psychology_tweet_116,‘Spanking is a form of violence against children that should no longer be a part of American childrearing.’ (££) ,"But there is a third reason not to spank our children, and that is a moral one.",‘Spanking is a form of violence against children that should no longer be a part of American childrearing.’ (££) ,"We thus have research-based and humanrights-based reasons for not spanking our children. But there is a third reason not to spank our children, and that is a moral one. By using the euphemistic term spanking, parents feel justified in hitting their children while not acknowledging that they are, in fact, hitting.","[3.0, 2.0, 4.0, 4.0]",Psychology,train,3.25,tweets,367548380329050113
10.1111/cdep.12038,Psychology_tweet_119,"For example, this study about spanking being both harmful and ineffective at what it purports to do: ",Spanking alone does not teach children why their behavior was wrong or what they should do instead .,"For example, this study about spanking being both harmful and ineffective at what it purports to do: ","It is difficult to imagine that a parent would be able to meet all these criteria when administering spanking; indeed, it would likely be both inadvisable and bordering on abusive if parents spanked children following every instance of a given misbehavior. Spanking alone does not teach children why their behavior was wrong or what they should do instead . Rather, it teaches them that they must behave when the threat of physical punishment exists, but once the threat is gone, they have no reason to behave appropriately .","[5.0, 5.0, 4.0, 2.0, 3.0]",Psychology,train,3.8,tweets,820676899890491393
10.1038/s41598-018-30980-y,Psychology_tweet_121,"Kids need naps. New study demonstrates that in order for kids to create and recall firm memories about an emotional situation (i.e., ""emotional memory,""), they need a lengthy nap + good sleep the following night  ","Supporting an interaction across sleep bouts, SWA in the nap negatively predicted ΔRecall nap (B = −0.601, p = 0.008; 95% CI: [−2.982, −0.517]; Fig.","Kids need naps. New study demonstrates that in order for kids to create and recall firm memories about an emotional situation (i.e., ""emotional memory,""), they need a lengthy nap + good sleep the following night  ","In light of the reduced accuracy across the nap predicting improvements in accuracy overnight (Fig. Supporting an interaction across sleep bouts, SWA in the nap negatively predicted ΔRecall nap (B = −0.601, p = 0.008; 95% CI: [−2.982, −0.517]; Fig. 3B ) and positively predicted ΔRecall overnight (B = 0.518, p = 0.028; 95% CI: [0.000, 0.005]; Fig.","[3.0, 3.0, 2.0]",Psychology,train,2.6666666666666665,tweets,1045387826920140805
10.1093/jcr/ucw012,Psychology_tweet_122,"How Behaviorally Targeted
Ads influence choices  ",This ad was not matched to the browsing behavior or demographic responses in either of the targeted conditions; this allowed us to test the effects of participants' perceptions of being targeted while holding the advertisement constant across conditions.,"How Behaviorally Targeted
Ads influence choices  ","Finally, study 4 shows that implied social labels only affect self-perceptions and behavior when there is a plausible connection between the label and past behavior (i.e., when targeting is at least moderately accurate). This ad was not matched to the browsing behavior or demographic responses in either of the targeted conditions; this allowed us to test the effects of participants' perceptions of being targeted while holding the advertisement constant across conditions. After indicating how much they liked the advertisement (1 ¼ Not at all,","[3.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,tweets,721803179319373824
10.1177/0141076814565942,Psychology_tweet_123,"Neurobollocks: Ritual circumcision &amp; risk of ASD in 0- to 9-year-old boys, via @username |  ","To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation.","Neurobollocks: Ritual circumcision &amp; risk of ASD in 0- to 9-year-old boys, via @username |  ","More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism. To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation. As expected, risk of asthma was independent of the boys' foreskin status, which is in accordance with prior findings for asthma in the first years of life.","[4.0, 3.0, 2.0, 4.0, 2.0]",Psychology,train,3.0,tweets,553661397146816512
10.1016/j.jpeds.2017.10.028,Psychology_tweet_124,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Hence, the modeling may occur in childhood due to direct experience of parental violence, witnessing interparental violence, or both.",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Due to item missingness, the sample sizes for sex, ethnicity, and highest parental education may not match. Hence, the modeling may occur in childhood due to direct experience of parental violence, witnessing interparental violence, or both. Our study has certain limitations.","[2.0, 2.0, 5.0, 4.0]",Psychology,train,2.0,tweets,955029736576692224
10.1016/j.jpeds.2017.10.028,Psychology_tweet_125,#Longevity Coaching Tip O’ the Day-Corporal punishment of children leads to violent adults. Another study. ,"Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96).",#Longevity Coaching Tip O’ the Day-Corporal punishment of children leads to violent adults. Another study. ,"Participants were Hispanic (32.6%), white (28.8%), African American (26.0%), and other (12.7%). Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","[4.0, 5.0, 3.0, 3.0, 4.0]",Psychology,train,3.8,tweets,940202043511398400
10.1038/s41598-017-03627-7,Psychology_tweet_126,Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"In line with our hypothesis, the male partner's empathic accuracy significantly moderated the effect of touch on synchronization for respiration fluctuations (F (4,28000) = 27.87, p < 0.0001, ΔBIC = 419439.8, ΔR 2 = 0.23).",Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"Empathic accuracy and trait empathy measurements demonstrated high correlation (r = 0.62, p < 0.001). In line with our hypothesis, the male partner's empathic accuracy significantly moderated the effect of touch on synchronization for respiration fluctuations (F (4,28000) = 27.87, p < 0.0001, ΔBIC = 419439.8, ΔR 2 = 0.23). More specifically, a high level of empathic accuracy (one standard deviation above the mean) compared to a low level (one standard deviation below the mean) was associated with increased coupling between female velocity and male acceleration in respiration during the touch condition (Δζ t(p) = 0.028, p < 0.001, 95% CI [0.016, 0.040]).","[5.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,3.6,tweets,877405828797665281
10.1073/pnas.1018601108,Psychology_tweet_127,Test Motivation found to be a key component in IQ test scores and their validity. via /r/science ,"If indeed test takers are less than maximally motivated in low-stakes research settings, material incentives should substantially improve their performance.",Test Motivation found to be a key component in IQ test scores and their validity. via /r/science ,"This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10. If indeed test takers are less than maximally motivated in low-stakes research settings, material incentives should substantially improve their performance. In 46 independent samples (n = 2,008), the mean effect of material incentives on IQ was medium to large: g = 0.64 [95% confidence interval (CI) = 0.39, 0.89], P < 0.001.","[5.0, 3.0, 2.0, 3.0, 4.0]",Psychology,train,3.4,tweets,526228478413520896
10.1177/0956797617692041,Psychology_tweet_128,Sugary drink regulations could increase or decrease consumption: from Leslie John and Christina Roberto @username ,Such norms can also be affected by the relative size of a serving container: A 20-oz drink seems smaller and more appropriate when it is the second-largest drink in a set as opposed to the largest .,Sugary drink regulations could increase or decrease consumption: from Leslie John and Christina Roberto @username ,"This happens in part by shifting consumption normsthat is, people's views of an appropriate serving size . Such norms can also be affected by the relative size of a serving container: A 20-oz drink seems smaller and more appropriate when it is the second-largest drink in a set as opposed to the largest . And when large serving sizes are viewed as appropriate, people feel less guilty about consuming them, which can encourage overconsumption )-compounded by the tendency to underestimate the size of large serving containers ).","[5.0, 1.0, 3.0, 3.0]",Psychology,train,2.0,tweets,882550998853615616
10.1007/s10803-014-2093-y,Psychology_tweet_129," #autism #bullying #assault In this report, 70% of autistic people report unwanted sexual contact.","Most concerning is the potential that the combination of age appropriate sexual motivation and interest, limited sexual knowledge and experiences, and additional social deficits, may place adolescents and young adults with ASD at increased risk for sexual violence victimization."," #autism #bullying #assault In this report, 70% of autistic people report unwanted sexual contact.","found that individuals with ASD were more likely to report television and ''by making mistakes'' in their list of sexual knowledge sources, and less likely to report social sources. Most concerning is the potential that the combination of age appropriate sexual motivation and interest, limited sexual knowledge and experiences, and additional social deficits, may place adolescents and young adults with ASD at increased risk for sexual violence victimization. Children with autism in the education system were not at an increased risk for sexual abuse compared to peers with other disabilities.","[5.0, 4.0, 2.0, 4.0]",Psychology,train,3.75,tweets,466102034396377088
10.1073/pnas.1505114112,Psychology_tweet_13,"Music training can enhance teenage brain development, study suggests ","Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years.","Music training can enhance teenage brain development, study suggests ","These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls. Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years. Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function.","[4.0, 5.0, 2.0, 4.0, 5.0]",Psychology,train,4.0,tweets,625652441149755392
10.1073/pnas.1417712112,Psychology_tweet_130,"Hunger promotes acquisition of nonfood objects. There is no free will.
","Finally, the positive influence of the hunger manipulation on acquisition held after including mood as a covariate [F(1, 58) = 6.61, P < 0.02].","Hunger promotes acquisition of nonfood objects. There is no free will.
","Mood did not influence the acquisition of binder clips (b = -0.048, SE = 0.208, t = -0.23, P > 0.80) or their evaluation (b = 0.058, SE = 0.119, t = 0.49, P > 0.60). Finally, the positive influence of the hunger manipulation on acquisition held after including mood as a covariate [F(1, 58) = 6.61, P < 0.02]. It also had a very small collection of snacks.","[4.0, 4.0, 2.0, 2.0, 4.0]",Psychology,train,3.2,tweets,567765107112165376
10.1007/s13524-014-0321-x,Psychology_tweet_131,"I always thought kids reduced happiness (in studies, not my own experience) but Mikko Myrskylä &amp; @username corrected me.

""The results...suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing.""
","First, if we observe that young parents have negative well-being trajectories but that older parents with more resources have easier transitions to parenthood, this may influence postponement of a first birth through social learning.","I always thought kids reduced happiness (in studies, not my own experience) but Mikko Myrskylä &amp; @username corrected me.

""The results...suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing.""
","Beyond the individual, social learning about the parental well-being trajectories of others may influence the quantum and tempo of fertility. First, if we observe that young parents have negative well-being trajectories but that older parents with more resources have easier transitions to parenthood, this may influence postponement of a first birth through social learning. Second, if we observe the transition to parenthood being accompanied by negative rather than positive changes in well-being, this can lead to lower fertility intentions, lower realized fertility, and also postponement if one surmises that less time is needed to have a smaller optimal number of children.","[3.0, 4.0, 2.0, 2.0, 1.0]",Psychology,train,2.4,tweets,1162831927553994753
10.1038/mp.2015.193,Psychology_tweet_134,Impact of videogame play on the brain's microstructural properties: cross ... - Nature...  #social #BPM,"However, the present study advanced our understanding of VGP as a daily habit of children and revealed that the conditions in which children play videogames for long periods of time may lead to unfavorable neurocognitive development, at least from a certain perspective.",Impact of videogame play on the brain's microstructural properties: cross ... - Nature...  #social #BPM,"Thus our study cannot directly explain how MD correlates of the amount of VGP in the identified areas are associated with the observed cognitive functional correlates of the amount of VGP and other cognitive functions. In conclusion, increased VGP is directly or indirectly associated with delayed development of the MD in extensive regions in the brain as well as verbal intelligence. However, the present study advanced our understanding of VGP as a daily habit of children and revealed that the conditions in which children play videogames for long periods of time may lead to unfavorable neurocognitive development, at least from a certain perspective.","[4.0, 4.0, 4.0, 3.0]",Psychology,train,3.75,tweets,684340512992579584
10.1093/geronb/gbt118,Psychology_tweet_135,"“More Years, Less Yawns”: #seniors report feeling much less tired than teenagers and younger adults ~ US study ",People who are more than 65 years of age are almost one point on a 0-6 scale less tired than people aged between 15 and 24.,"“More Years, Less Yawns”: #seniors report feeling much less tired than teenagers and younger adults ~ US study ","Contrary to much previous research, tiredness decreases with age. People who are more than 65 years of age are almost one point on a 0-6 scale less tired than people aged between 15 and 24. Clinical implications and methodological limitations are discussed.","[5.0, 4.0, 5.0, 4.0]",Psychology,train,4.5,tweets,407566858213019648
10.1186/2193-7680-3-1,Psychology_tweet_137,New paper on transport-crime analysis techniques: Measuring crime risk in/around underground mass transit systems: ,This has clear policy implications for policing these settings and highlights the importance of joint operations and information sharing between transit agencies and local police forces operating near major transit systems.,New paper on transport-crime analysis techniques: Measuring crime risk in/around underground mass transit systems: ,"The findings suggest offenders who operate below ground may also operate above ground on major transit systems. This has clear policy implications for policing these settings and highlights the importance of joint operations and information sharing between transit agencies and local police forces operating near major transit systems. Four potential settings of theft are identified; in the vicinity of a station but outside its boundary; inside a station boundary before the paid access barrier; within the paid access barrier outside of carriages, and; inside a rail carriage.","[4.0, 4.0, 1.0, 3.0, 1.0]",Psychology,train,2.0,tweets,432985448793645056
10.1007/s10919-013-0170-0,Psychology_tweet_138,Putting a hand on your heart when you speak with someone increases your perceived honesty by others according to fou…,"Third, the first two of the present studies showed the perception of others to be influenced by the hand-over-heart gesture, and by definition, self-perception processes cannot explain the perceptions of other persons.",Putting a hand on your heart when you speak with someone increases your perceived honesty by others according to fou…,"For example, a great majority of the participants of one multi-sample study (N [ 800 including pupils, students, and employees), showed quite extreme estimates of their honesty and other moral traits , and extremity of ratings typically goes hand-in-hand with their subjective certainty. Third, the first two of the present studies showed the perception of others to be influenced by the hand-over-heart gesture, and by definition, self-perception processes cannot explain the perceptions of other persons. All of this suggests that self-perception processes do not provide a plausible explanation for the present data.","[4.0, 5.0, 3.0]",Psychology,train,4.0,tweets,446650812769378304
10.1001/jamapsychiatry.2015.0627,Psychology_tweet_14,"Risk for #tic disorders, including #Tourette syndrome, increased w/ degree of #genetic relatedness. ","CONCLUSIONS AND RELEVANCE Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions.","Risk for #tic disorders, including #Tourette syndrome, increased w/ degree of #genetic relatedness. ","There were no differences in familial risk or heritability between male and female patients. CONCLUSIONS AND RELEVANCE Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions. Second, families were primarily recruited from specialist clinics, potentially resulting in the inclusion of more severe and impaired cases.","[3.0, 4.0, 5.0, 3.0]",Psychology,train,3.75,tweets,612676857180332032
10.3758/s13414-015-0969-3,Psychology_tweet_140,Difference in attention at 3 months assoc w/ C-section vs. vaginal birth ($) ,"Thus, irrespective of whether infants had to initiate a saccadic eye movement to a single item or to a stimulus item in the presence of a competing item, those who were delivered by caesarean section took longer to allocate attention and initiate that eye movement than did those who were delivered vaginally.",Difference in attention at 3 months assoc w/ C-section vs. vaginal birth ($) ,"3 , the interaction of target condition and birth experience was also not significant, F(1, 352) = 0.08, n.s., indicating that the differences in saccade latencies of vaginally delivered infants relative to infants delivered by caesarean section were similar when a target was presented alone (vaginal . Thus, irrespective of whether infants had to initiate a saccadic eye movement to a single item or to a stimulus item in the presence of a competing item, those who were delivered by caesarean section took longer to allocate attention and initiate that eye movement than did those who were delivered vaginally. Alternatively, the slowed attentional responses of caesarean-section infants relative to vaginal infants might have been due to other factors.","[1.0, 5.0, 4.0, 4.0, 5.0]",Psychology,train,4.0,tweets,672758951507861504
10.1016/j.jesp.2018.07.004,Psychology_tweet_141,Being consequentialist may harm how we are perceived by others - New study from Crockett Lab! ,"In this way, the consequentialist action in our impartiality dilemmas we used in this study -and especially the spending money variant -directly match onto the action that we should do on effective altruism principles.",Being consequentialist may harm how we are perceived by others - New study from Crockett Lab! ,"Finally, our work has practical implications concerning how in everyday life groups and individuals who advocate a more impartial, welfare-maximising consequentialist approach to moral decisionssuch as the ""effective altruism"" movement -might expect to be perceived, and how this might limit their advocacy. In this way, the consequentialist action in our impartiality dilemmas we used in this study -and especially the spending money variant -directly match onto the action that we should do on effective altruism principles. Our work suggests that effective altruists may face stumbling blocks in how they are perceived by others and that, while receiving far less criticism than consequentialists can receive for endorsing instrumental harm, this may still have harmful consequences for how the movement is perceived and therefore, presumably, how many people join the movement and adopt its principles.","[4.0, 4.0, 3.0, 5.0]",Psychology,train,4.0,tweets,1032929807762444288
10.1007/s12529-014-9448-9,Psychology_tweet_142,Mindfulness is correlated with a greater consumption of fruits and veg and non-smoking: ,These intervention findings are supported by a recent meta-analysis of 11 observational studies that showed significant inverse associations between dispositional mindfulness and smoking (aggregate r= −0.14; p<0.001) consistent with findings in the current study.,Mindfulness is correlated with a greater consumption of fruits and veg and non-smoking: ,"Prevalence Ratio methodologically rigorous randomized controlled trials to date demonstrated a 31 % smoking abstinence rate for those randomized to mindfulness training vs. 6 % in the active control group at 17 weeks follow-up (p= 0.012) . These intervention findings are supported by a recent meta-analysis of 11 observational studies that showed significant inverse associations between dispositional mindfulness and smoking (aggregate r= −0.14; p<0.001) consistent with findings in the current study. With regard to obesity, to our knowledge, this is the first study to evaluate associations of dispositional mindfulness with directly assessed BMI.","[3.0, 3.0, 1.0, 4.0]",Psychology,train,2.75,tweets,529286716038074368
10.1002/ejp.927,Psychology_tweet_143,PubMED:- Putting pain out of mind with an 'out of body' illusion.  #fibro,Conclusion: These findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception.,PubMED:- Putting pain out of mind with an 'out of body' illusion.  #fibro,"Results: We found that full body illusions were experienced by patients with chronic pain and further, that pain intensity was reduced by an average of 37% after illusion (synchronous) conditions. Conclusion: These findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception. Significance: Pain intensity in chronic pain patients was reduced by 37% by 'out of body' illusions.","[4.0, 3.0, 4.0, 3.0]",Psychology,train,3.5,tweets,763677607996993537
10.1080/16066359.2017.1311877,Psychology_tweet_144,New #ReadiLab piece online describing enhanced pleasure from smoking cigs while drinking but not while smoking pot ,"In contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana (5.3 ± 2.7, t (199) ¼ 1.7, p ¼ .09).",New #ReadiLab piece online describing enhanced pleasure from smoking cigs while drinking but not while smoking pot ,"Individuals reported an increase in perceived pleasure from smoking cigarettes when drinking alcohol (7.0 ± 2.2 versus null hypothesis 5 ¼ ""no increase or decrease in pleasure""; t (199) ¼13.0, p < .001). In contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana (5.3 ± 2.7, t (199) ¼ 1.7, p ¼ .09). Perceived pleasure from smoking cigarettes did not differ by frequency of binge drinking (F (3,200) ¼ 0.84, p ¼ .47): nonbinge (7.1 ± 2.1), 1-3 binge days (6.8 ± 2.3), 4-8 binge days (7.0 ± 2.1), 9 þ binge days (7.6 ± 2.2).","[1.0, 1.0, 4.0, 4.0]",Psychology,train,4.0,tweets,857108199056568320
10.1016/j.jarmac.2014.03.005,Psychology_tweet_145,Meta-analysis on the effectiveness of reducing false memories.. ,"In short, there is clear meta-analytic evidence that post-warnings lead to a real improvement of memory performance for original details that have been the target of misinformation, whereas the evidence for associated costs to control memory performance is more tenuous.",Meta-analysis on the effectiveness of reducing false memories.. ,"By comparison, the 1.21 control costs odds ratio is much lower and does not differ significantly from the no-effect value of 1. In short, there is clear meta-analytic evidence that post-warnings lead to a real improvement of memory performance for original details that have been the target of misinformation, whereas the evidence for associated costs to control memory performance is more tenuous. Across 25 direct comparisons (stemming from 10 papers), misled and control Misinformation Endorsement in the no-warning condition was 42.3% and 17.7%, respectively.","[2.0, 4.0, 4.0]",Psychology,train,3.333333333333333,tweets,453894251802558464
10.1016/j.brat.2017.09.010,Psychology_tweet_146,Great study from W. Britton et al -  3 armed RCT validating focused attention and open monitoring elements of mindfulness based cognitive therapy! ,Mindfulness research in general could benefit from employing the SOBC experimental medicine approach.,Great study from W. Britton et al -  3 armed RCT validating focused attention and open monitoring elements of mindfulness based cognitive therapy! ,"Verification of target engagement with different assays of attention control and emotional non-reactivity, including behavioral, neuroimaging and peripheral biological assays, will promote cross-validation of reliable target engagement. Mindfulness research in general could benefit from employing the SOBC experimental medicine approach. The SOBC experimental medicine approach will not only help MBIs become maximally effective, but also provide essential mechanistic information that will help tailor the intervention and instructor training to specific populations and conditions.","[3.0, 2.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,tweets,938317197268738050
10.1111/cdev.12250,Psychology_tweet_148,Pseudomature traits that make you cool in middle school predict problems later in life  #psychology #teens,"In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways.",Pseudomature traits that make you cool in middle school predict problems later in life  #psychology #teens,"Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior. In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways. Each of these behaviorsminor deviance, a focus on physical appearance in choosing friends, and precocious romantic activityis clearly distinct, yet each shares in common the potential to provide a veneer of maturity to the early adolescent seeking to enhance status with his or her peers.","[4.0, 2.0, 3.0, 3.0]",Psychology,train,3.0,tweets,482156096191463424
10.1093/chemse/bjt066,Psychology_tweet_149,@username New study on odor labels and odor perceptions. ,"Because half of the odors had a positive food labels and negative nonfood labels, it could be argued that the positive food labels in themselves led to the increase in the edibility ratings of these odors.",@username New study on odor labels and odor perceptions. ,"A limitation of the present study is that the design is not balanced in terms of label edibility and therefore could bias our findings of the impact of labels on odor perception. Because half of the odors had a positive food labels and negative nonfood labels, it could be argued that the positive food labels in themselves led to the increase in the edibility ratings of these odors. Despite this limitation, we do find this to be true even for the 2 odors with both positive and negative nonfood labels, which supports that we found an effect of edibility on labeled manipulated odors.","[2.0, 3.0, 2.0, 1.0, 3.0]",Psychology,train,2.2,tweets,434062321556942848
10.1001/jamapsychiatry.2013.4081,Psychology_tweet_150,"Trophy wife alert: ""The offspring of younger mothers &amp; older fathers are at risk for ... mental health disorders"" ","Within this group, we found no prominent association between parental age and the risk for bipolar disorder.","Trophy wife alert: ""The offspring of younger mothers &amp; older fathers are at risk for ... mental health disorders"" ","For the general category of mood disorders, the offspring of teenaged mothers or fathers and the offspring of older fathers had small but significantly increased risks (compared with the reference category). Within this group, we found no prominent association between parental age and the risk for bipolar disorder. The risk for schizophrenia and related disorders was associated with older fathers (≥45 years vs the reference category; IRR, For the broad group of neurotic and stress-related disorders (ICD-10-DRC codes F40-F48), the offspring of teenaged mothers were at the highest risk (IRR, 1.49 [95% CI, 1.45-","[2.0, 4.0, 1.0, 2.0]",Psychology,train,2.25,tweets,426949164384018432
10.1073/pnas.1505114112,Psychology_tweet_151,Also interesting for #socialclass studies: #Music training for teenagers may sharpe hearing and language skills ,We show that in-school music training changes the course of adolescent brain development.,Also interesting for #socialclass studies: #Music training for teenagers may sharpe hearing and language skills ,"Moreover, given that the cortical N1 onset response emerges during adolescence while the P1 response declines , and that We show that in-school music training changes the course of adolescent brain development. Relative to an active control group that shows the expected wane in subcortical response consistency, adolescents undertaking in-school music training maintained heightened neural consistency throughout high school.","[4.0, 4.0, 3.0, 3.0]",Psychology,train,3.5,tweets,623476911486930944
10.1111/cdep.12038,Psychology_tweet_152,"both in title and in content, my new favorite scholarly piece on spanking: ",Reducing parents' use of spanking may go a long way toward reducing the number of children who suffer physical abuse each year.,"both in title and in content, my new favorite scholarly piece on spanking: ","The link between spanking and physical abuse is the most disturbing of these unintended effects, but it should not be a surprising one; both parental acts involve hitting, and purposefully hurting, children. Reducing parents' use of spanking may go a long way toward reducing the number of children who suffer physical abuse each year. Human rights-based arguments have little influence in the United States until we ratify the Convention on the Rights of the Child; the United States is one of only three countries not to have done so (the others are Somalia and South Sudan, the latter of which gained independence in 2011).","[4.0, 2.0, 3.0, 3.0, 2.0]",Psychology,train,2.8,tweets,380498625802936321
10.1073/pnas.1505114112,Psychology_tweet_153,Music training in school changes brain development and improves #literacy skills ,The maintenance of response consistency in the music training group may prolong sensitivity to auditory learning.,Music training in school changes brain development and improves #literacy skills ,"Thus, music training may maintain heightened synaptic density within the auditory system to enable the learning and performance of challenging auditory tasks, much as songbirds show seasonal increases in synaptogenesis that coincide with the onset of the preferential period for learning new songs . The maintenance of response consistency in the music training group may prolong sensitivity to auditory learning. Future work could test this hypothesis by measuring auditory learning in adolescents with or without prior musical experience.","[2.0, 1.0, 4.0, 3.0]",Psychology,train,2.5,tweets,623814831670476800
10.1177/0141076814565942,Psychology_tweet_154,"@username The circumcision, #acetaminophen &amp; autism studies:   (Circumcision is associated w/ autism &amp; ADHD only after Danish guidelines suggest Tylenol use-boys &lt;5yrs only) Animal model  Efficacy? ",The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) .,"@username The circumcision, #acetaminophen &amp; autism studies:   (Circumcision is associated w/ autism &amp; ADHD only after Danish guidelines suggest Tylenol use-boys &lt;5yrs only) Animal model  Efficacy? ","The HR was higher, though not significantly so, for boys circumcised at age 24 months or older (HR ¼ 1.96; 95% CI: 0.93-4.14), an estimate based on only seven cases of ASD in that group ( Table 2) . The increased risk of ASD in circumcised boys under the age of 5 years was present among boys in both Muslim and non-Muslim families ( Table 2) . Risk in this age group was markedly elevated among boys in non-Muslim families (HR ¼ 4.23; 95% CI: 1.90-9.44), a finding based on six ASD cases in circumcised boys versus 1165 cases in intact boys.","[4.0, 5.0, 3.0, 3.0, 3.0]",Psychology,train,3.6,tweets,985565035048112128
10.1177/0141076814565942,Psychology_tweet_156,always wanted to discuss circumcision on #autism boards? Here is your chance ,"With 57 ASD cases in ritually circumcised boys and 4929 ASD cases in intact boys, the overall ASD risk in the age interval 0-9 years was 46% increased in ritually circumcised boys (HR ¼ 1.46; 95% CI: 1.11-1.93).",always wanted to discuss circumcision on #autism boards? Here is your chance ,"When considered simultaneously, gestational age and mother's marital status were no longer independent ASD risk factors. With 57 ASD cases in ritually circumcised boys and 4929 ASD cases in intact boys, the overall ASD risk in the age interval 0-9 years was 46% increased in ritually circumcised boys (HR ¼ 1.46; 95% CI: 1.11-1.93). This was due to noticeably increased ASD risk in the first 0-4 years of life (HR ¼ 1.80; 95% CI: 1.25-2.60), but not in the 5-9 years age interval (HR ¼ 1.15; 95% CI: 0.75-1.77).","[4.0, 5.0, 2.0, 3.0, 4.0]",Psychology,train,3.6,tweets,553483150404640768
10.1016/j.jpeds.2017.10.028,Psychology_tweet_158,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,"Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings.",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,"This latter concern is tempered by the fact that prevalence of corporal punishment and dating violence in the current population was similar to nationally representative samples. Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence.","[2.0, 3.0, 3.0]",Psychology,train,2.6666666666666665,tweets,940635027464912897
10.1177/0141076814565942,Psychology_tweet_159,"Interestingly, the circumcision-autism risk paper  makes mention of a possible pain relief link??","However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases.","Interestingly, the circumcision-autism risk paper  makes mention of a possible pain relief link??","Among boys in Muslim families, risk of hyperkinetic disorder did not depend on the boys' foreskin status (HR ¼ 1.08; 95% CI: 0.77-1.52). However, risk was significantly increased among circumcised boys in non-Muslim families (HR ¼ 1.81; 95% CI: 1.11-2.96), and risk appeared to be particularly high in the <5 years age window (HR ¼ 3.60; 95% CI: 1.16-11.18), although the latter observation was based on only three cases. Associations of ritual circumcision with risk of asthma were consistently negative, both in the 0-4 years (HR ¼ 0.91; 95% CI: 0.78-1.06) and the 5-9 years age interval (HR ¼ 1.16; 95% CI: 0.89-1.51), yielding an inconspicuous overall HR estimate (HR ¼ 0.96; 95% CI: 0.84-1.10) based on a total of 235 cases of asthma in circumcised boys versus 29,002 cases in intact boys.","[2.0, 1.0, 1.0, 3.0, 1.0]",Psychology,train,1.6,tweets,553524239329140736
10.1177/0141076814565942,Psychology_tweet_16,Ritual circumcision and risk of autism  Let's wait for more research on this hypothesis.,"ASD risk in girls was not associated with family factors linked to ritual male circumcision (HR ¼ 1.17; 95% CI: 0.54-2.55), based on seven ASD cases in girls with a ritually circumcised brother and 1012 ASD cases in girls without a ritually circumcised brother.",Ritual circumcision and risk of autism  Let's wait for more research on this hypothesis.,"For boys in the 0-4 years age interval, risk of infantile autism in circumcised boys was twice that of intact boys (HR ¼ 2.06; 95% CI: 1.36-3.13, based on 27 cases in circumcised boys and 785 cases in intact boys); the risk of all other types of ASD combined was inconspicuous in the same age group (HR ¼ 1.21; 95% CI: 0.55-2.66, based on seven cases in circumcised boys and 540 cases in intact boys). ASD risk in girls was not associated with family factors linked to ritual male circumcision (HR ¼ 1.17; 95% CI: 0.54-2.55), based on seven ASD cases in girls with a ritually circumcised brother and 1012 ASD cases in girls without a ritually circumcised brother. Ritual circumcision among Danish boys is linked to an overall 46-62% increase in ASD risk in the first 10 years of life, with the upper risk estimate obtained after restriction to the period with the most complete data.","[2.0, 3.0, 2.0]",Psychology,train,2.333333333333333,tweets,554696253800742912
10.1016/j.jpeds.2017.10.028,Psychology_tweet_160,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Future research would benefit by including corroborating reports (eg, by parents) and/or a more comprehensive measure of corporal punishment.",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"Thus, it is possible that participants may have, on the one hand, opted for more socially desirable responses, or on the other, inflated or misremembered actual events. Future research would benefit by including corroborating reports (eg, by parents) and/or a more comprehensive measure of corporal punishment. Second, participants were all located in the southern US, which may limit generalizability to other regions of the country.","[3.0, 2.0, 1.0, 2.0]",Psychology,train,2.0,tweets,946221716145045504
10.1038/s41598-017-03627-7,Psychology_tweet_161,Power of touch ✋️in relieving pain  ,"The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 .",Power of touch ✋️in relieving pain  ,"Moreover, tactile-induced analgesia 66 correlates with activations in brain areas related to multimodal neural activity 67 and emotional processes . The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 . The ACC appears to play a role in a variety of autonomic functions, such as regulating heart rate and blood pressure 76 .","[4.0, 5.0, 4.0, 3.0, 5.0]",Psychology,train,4.2,tweets,879074742204084224
10.1038/s41598-017-03627-7,Psychology_tweet_162," When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain subside…","That is, we observed a shift from exhalation to inhalation in a participant when their partner inhales (the heart rate shifts from a decrease to an increase when the partner exhibited an increase in heart rate)."," When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain subside…","The results show that both empathic accuracy and trait empathy moderated inter-partner physiological coupling, so that dyads with highly empathic male partners demonstrated increased coupling. That is, we observed a shift from exhalation to inhalation in a participant when their partner inhales (the heart rate shifts from a decrease to an increase when the partner exhibited an increase in heart rate). Moreover, in the couples where the female partners reported greater touch-related analgesia, we observed enhanced physiological coupling.","[4.0, 4.0, 4.0, 3.0]",Psychology,train,3.75,tweets,877661666539958272
10.1038/s41598-017-03627-7,Psychology_tweet_163,"Look: When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain s…  ","We found significant moderation of the effect of women's analgesia and touch on the cross-partner synchronization in velocity of respiration fluctuations (F (4,28000) = 26.59, p < 0.0001, ΔBIC = −418367.9, ΔR 2 = 0.19).","Look: When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain s…  ","The corresponding contrasts were not significant in the condition without partner touch (Δζ nt(p) = 0.002, p = 0.56, men), (Δζ nt(p) = 0.001, p < 0.73, women) ( Fig. We found significant moderation of the effect of women's analgesia and touch on the cross-partner synchronization in velocity of respiration fluctuations (F (4,28000) = 26.59, p < 0.0001, ΔBIC = −418367.9, ΔR 2 = 0.19). Higher levels of women's analgesia predicted increased coupling between female velocity and male acceleration (Δζ t(p) = 0.027, p < 0.001, 95% CI [0.015, 0.039]) and increased associations between male velocity and female acceleration (Δζ t(p) = 0.068, p < 0.001, 95% CI [0.042, 0.093]) in the touch condition.","[3.0, 4.0, 5.0, 5.0, 1.0]",Psychology,train,4.0,tweets,877684383725092865
10.1038/s41598-017-03627-7,Psychology_tweet_164,"When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain subsides ","Empathic accuracy and touch moderated the effect of synchronization in heart rate (F (4,13000) = 20.73, p < 0.0001, ΔBIC = −265162.9, ΔR 2 = 0.24).","When an empathetic partner holds a lover's hand, their heart rates and breathing rates sync and their pain subsides ","The same pattern of moderation effects emerged in the heart rate analysis. Empathic accuracy and touch moderated the effect of synchronization in heart rate (F (4,13000) = 20.73, p < 0.0001, ΔBIC = −265162.9, ΔR 2 = 0.24). High as opposed to low levels of empathic accuracy predicted greater coupling between female velocity and The corresponding contrasts were not significant in the condition without partner touch (Δζ nt(p) = 0.008, p = 0.28, males), (Δζ nt(p) = 0.008, p = 0.34, females).","[4.0, 3.0, 5.0]",Psychology,train,4.0,tweets,877703974186385408
10.1001/jamapsychiatry.2018.0296,Psychology_tweet_168,Are time-related #deployment variables associated with subsequent risk of #suicide attempt among #USArmy enlisted #soldiers? Find out via @username ,Multivariable population-attributable risk proportions were 14.2% for deployment within the first 12 months of service and 4.0% for DT of 6 months or less.,Are time-related #deployment variables associated with subsequent risk of #suicide attempt among #USArmy enlisted #soldiers? Find out via @username ,Analysis of 2-way interactions indicated that the associations of early deployment and DT with SA risk were not modified by other characteristics. Multivariable population-attributable risk proportions were 14.2% for deployment within the first 12 months of service and 4.0% for DT of 6 months or less. CONCLUSIONS AND RELEVANCE Time in service before first deployment and DT are modifiable risk factors for SA risk among soldiers.,"[1.0, 3.0, 5.0, 3.0]",Psychology,train,2.0,tweets,987003134319910912
10.1177/0956797613512129,Psychology_tweet_169, this strategy works with human nature to encourage saving. happy holidays @username update followers!,"While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism.", this strategy works with human nature to encourage saving. happy holidays @username update followers!,"In contrast, the linear savings method encourages deferral of the savings task to the future, inflating savings predictions in the distant future, but dampening current saving. While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism. Practically, people can make savings decisions at any time, and we surmise that deferral under the linear savings method may continue unabated as the person's distant future becomes the near future and eventually the present.","[4.0, 2.0, 5.0, 3.0, 3.0]",Psychology,train,3.4,tweets,415149659426803712
10.1073/pnas.1902058116,Psychology_tweet_170,🚨 STOP THE PRESS: HAs social media destroyed a generation? Probably not. 🚨 Research published today in @username puts an end to overhyped correlational results by providing concrete longitudinal evidence:  (1/11) ,"We found that social media use is not, in and of itself, a strong predictor of life satisfaction across the adolescent population.",🚨 STOP THE PRESS: HAs social media destroyed a generation? Probably not. 🚨 Research published today in @username puts an end to overhyped correlational results by providing concrete longitudinal evidence:  (1/11) ,"We found that social media use is not, in and of itself, a strong predictor of life satisfaction across the adolescent population. Instead, social media effects are nuanced, small at best, reciprocal over time, gender specific, and contingent on analytic methods. Furthermore, the volume of data under analysis, paired with unchecked analytical flexibility, enables selective research reporting, biasing the literature toward statistically significant effects (3, 4).","[2.0, 4.0, 5.0, 1.0, 2.0]",Psychology,train,4.0,tweets,1125490426138566656
10.1073/pnas.1702671114,Psychology_tweet_171,"Discovered that temporal summation, a process many animals share, lies at the core of adaptive vocal volume control ","For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured.","Discovered that temporal summation, a process many animals share, lies at the core of adaptive vocal volume control ","First, the duration of the vocalizations under investigation sets the finest latency measurement resolution. For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured. For example, using the data from the 500-ms continuous noise experiment (experiment 1) we estimated the response latency for the Lombard effect to be between 25 and 75 ms because calls were 2.2 ± 0.7 dB more intense for the 75-ms call group statistically, but not for the 25-ms call group.","[3.0, 2.0, 2.0, 3.0]",Psychology,train,2.5,tweets,879543017899606016
10.1098/rspb.2015.1292,Psychology_tweet_174,New today @username. Experts in face processing learn rules about matching identity across unfamiliar faces. ,"To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks.",New today @username. Experts in face processing learn rules about matching identity across unfamiliar faces. ,"Although examiners' performance was not statistically superior to controls in all experiments, it was always statistically superior to the student performance. To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks. Closer analysis also revealed two qualitative differences between examiners and non-expert groups.","[1.0, 3.0, 2.0, 2.0]",Psychology,train,2.0,tweets,639162745032699904
10.1186/2045-5380-3-19,Psychology_tweet_175,What is the role of the #endocannabinoid system in #stress? Read the latest review from @username ,"Second, basal eCB signaling appears to be reduced in individuals afflicted with stress-related psychiatric conditions, such as major depression or PTSD, suggesting that impaired eCB signaling is related to the development of these conditions.",What is the role of the #endocannabinoid system in #stress? Read the latest review from @username ,"First, eCB signaling is responsive to stress and deficient eCB activity is associated with increased stress responses, suggesting that eCB signaling constrains the magnitude of the stress response. Second, basal eCB signaling appears to be reduced in individuals afflicted with stress-related psychiatric conditions, such as major depression or PTSD, suggesting that impaired eCB signaling is related to the development of these conditions. Whether the reduction in eCB signaling is a predisposing factor or a burden of the disease itself, is yet to be determined, as is whether these changes in circulating eCB levels are reflective of central eCB activity.","[3.0, 4.0, 3.0]",Psychology,train,3.333333333333333,tweets,392666652640178176
10.1038/s41598-019-39932-6,Psychology_tweet_176,"Our paper on facial replication in sunbears is out today in @username 

Super proud of Derry Taylor and happy to have contributed to this research!
","However, this possibility requires further research into whether gentle play is more likely to transition into rough play when exact facial mimicry occurs.","Our paper on facial replication in sunbears is out today in @username 

Super proud of Derry Taylor and happy to have contributed to this research!
","Perhaps exact facial mimicry helps to signal a readiness to transition into rougher play in sun bears, which is consistent with the proposition that facial communication helps regulate high play intensity 22 , and is a pattern previously associated with canid play signalling 19 . However, this possibility requires further research into whether gentle play is more likely to transition into rough play when exact facial mimicry occurs. Alternatively, exact facial mimicry might be more directly linked to gentle www.nature.com/scientificreports www.nature.com/scientificreports/ play and hereby function, for instance, to strengthen social bonds 24 .","[1.0, 1.0, 2.0]",Psychology,train,1.3333333333333333,tweets,1108749060310294528
10.1093/schbul/sbv109,Psychology_tweet_177,"Grey matter loss appears to be a universal process in #schizophrenia, regardless of #ethnicity ","For example, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations.","Grey matter loss appears to be a universal process in #schizophrenia, regardless of #ethnicity ","the incidence and clinical expression of schizophrenia vary according to a number of sociodemographic factors including, amongst others, the ethnic origin of the patients under investigation. For example, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations. 5 In addition, the content of hallucination and delusions is also strongly influenced by the patient's ethnic milieus.","[1.0, 1.0, 2.0, 3.0]",Psychology,train,1.75,tweets,646642671327518720
10.1093/jcr/ucw035,Psychology_tweet_179,"Year of the Woman?  @username 

A 2016 study from the Journal of Consumer Research showed women are better at compromising, stating compromise is “nearly guaranteed when a woman is involved in decision-making pairs.” ","If men make a joint choice on an appetizer or a piece of real estate, for example, they may choose a more expensive alternative than if they choose with women or alone.","Year of the Woman?  @username 

A 2016 study from the Journal of Consumer Research showed women are better at compromising, stating compromise is “nearly guaranteed when a woman is involved in decision-making pairs.” ","To use this insight, marketers may want to prompt men to make decisions with other men. If men make a joint choice on an appetizer or a piece of real estate, for example, they may choose a more expensive alternative than if they choose with women or alone. Finally, marketers using the compromise effect for new product introduction, positioning, product assortments, and product deletions need to consider whether the target consumers for their products are likely to purchase them in joint or individual decision-making contexts, as well as the likely gender composition of the decision-making pairs.","[4.0, 5.0, 1.0, 2.0, 5.0]",Psychology,train,4.0,tweets,968803196327129088
10.1038/s41598-017-03627-7,Psychology_tweet_18,Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"Thus, future research should test the role of oxytocin in touch-related analgesia.",Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 . Thus, future research should test the role of oxytocin in touch-related analgesia. It is important to note that our findings of interpersonal coupling during touch can also be explained by the phenomenon of Huygens synchronization of two connected pendulum clocks 83 .","[2.0, 3.0, 2.0, 1.0]",Psychology,train,2.0,tweets,885195841073557504
10.1016/j.appet.2014.10.004,Psychology_tweet_180,"Acceptance-based skills,commitment 2 defined values &amp; decision making awareness promising strategies 4 weight control:","Moreover, when administered by weight control experts, as opposed to graduate student trainees, weight loss was significantly higher in ABT than standard behavioral treatment at 6-month follow-up (11.0% vs. 4.8).","Acceptance-based skills,commitment 2 defined values &amp; decision making awareness promising strategies 4 weight control:","Weight loss at 18 months, i.e., 6-month follow-up, was somewhat larger for those receiving ABT, but moderation analyses revealed that this advantage was especially powerful for participants with particular vulnerabilities, i.e., mood disturbance, elevated responsivity to food cues and high disinhibition . Moreover, when administered by weight control experts, as opposed to graduate student trainees, weight loss was significantly higher in ABT than standard behavioral treatment at 6-month follow-up (11.0% vs. 4.8). This result raises the possibility that those who have more experience in administering behavioral weight control interventions may be more successful at integrating acceptance-based principles into the behavioral program.","[4.0, 1.0, 2.0, 2.0, 2.0]",Psychology,train,2.2,tweets,530727599786708992
10.1007/s10071-015-0889-6,Psychology_tweet_181,"Famed Gorilla Koko exercises voluntary control over 9 discrete breathing-related behaviors. 
 ","Based on these and other findings, we suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes.","Famed Gorilla Koko exercises voluntary control over 9 discrete breathing-related behaviors. 
 ","Our analysis shows that Koko exercises voluntary control over the performance of nine distinctive VBBs, which involve variable coordination of her breathing, larynx, and supralaryngeal articulators like the tongue and lips. Based on these and other findings, we suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes. For example, Goodall, generalizing from her observations of free-ranging chimpanzees in the Gombe Reserve, came to the conclusion that ''the production of sound in the absence of the appropriate emotional state seems to be an almost impossible task for a chimpanzee' ' (1986: 125) .","[1.0, 2.0, 2.0, 3.0, 3.0]",Psychology,train,2.2,tweets,616902993921855488
10.1002/erv.2553,Psychology_tweet_182,"Numerous reputable doctors stand behind the science of the #ninetruths - Eating Disorders are biological, brain-based illnesses with a genetic component. @username, let's talk about it. ",Signs and symptoms of an eating disorder should always be taken seriously and not dismissed or minimized.,"Numerous reputable doctors stand behind the science of the #ninetruths - Eating Disorders are biological, brain-based illnesses with a genetic component. @username, let's talk about it. ","On average, the BMI of individuals with AN is lower than the BMI of those with BN, which is lower than the BMI of those with BED. Signs and symptoms of an eating disorder should always be taken seriously and not dismissed or minimized. Immediate attention is warranted, and a comprehensive evaluation should be the first step in treatment planning (American Psychiatric Association, 2006; National Collaborating Centre for Mental Health, 2004 ).","[2.0, 1.0, 2.0, 4.0]",Psychology,train,2.25,tweets,989093317831995394
10.1016/j.neuron.2014.08.020,Psychology_tweet_185,'Upstream Color' in a neuro tweet? LIP neurons exhibit integrative representations of both color &amp; motion features ,We focused on neurons that were both color and direction selective using the three-way ANOVA or showed significant color and direction tuning shifts (n = 71) during the DCM task (using different populations led to similar results).,'Upstream Color' in a neuro tweet? LIP neurons exhibit integrative representations of both color &amp; motion features ,"This raises a question about whether feature encoding in LIP is used to detect and respond to match stimuli. We focused on neurons that were both color and direction selective using the three-way ANOVA or showed significant color and direction tuning shifts (n = 71) during the DCM task (using different populations led to similar results). Responses to match stimuli ( Figure S2A ) were higher than for nonmatch stimuli for both sample A (paired t test, p = 4 3 10 À5 ) and B (p = 0.001) trials.","[3.0, 5.0, 4.0]",Psychology,train,4.0,tweets,507777769640439808
10.1287/orsc.2015.0965,Psychology_tweet_186,How a company's structure affects the leadership gender gap: @username  + RainaBrands @username research ,"To the extent that these interactions are perceived by followers as arising unprompted by the leader, one implication of our findings is that perceptions of agency and communality arise not only from men's and women's behavior but also from the social context in which those behaviors occur.",How a company's structure affects the leadership gender gap: @username  + RainaBrands @username research ,"When applied to leadership, this means that when women enact the agentic behaviors necessary for leadership, they are penalized for being insufficiently communal, resulting in negative evaluations of their leadership abilities . To the extent that these interactions are perceived by followers as arising unprompted by the leader, one implication of our findings is that perceptions of agency and communality arise not only from men's and women's behavior but also from the social context in which those behaviors occur. However, it may be that leaders are perceived by the followers to be responsible for cultivating the social structure in their teams along centralized and cohesive dimensions.","[3.0, 2.0, 2.0, 4.0]",Psychology,train,2.75,tweets,611625441250545664
10.1073/pnas.1524982113,Psychology_tweet_187,Blind people recruit visual areas during mathematical calculations. Evidence of brain plasticity: ,"Participants with larger accuracy differences between the hardest and easiest math conditions also showed a larger activation difference between these conditions in number-responsive visual cortex (rMOG) (R 2 = 0.28, P = 0.03; Fig.",Blind people recruit visual areas during mathematical calculations. Evidence of brain plasticity: ,"In the blind group, visual cortex activity correlated with performance on the math task. Participants with larger accuracy differences between the hardest and easiest math conditions also showed a larger activation difference between these conditions in number-responsive visual cortex (rMOG) (R 2 = 0.28, P = 0.03; Fig. This correlation was not significant in the sighted participants (R 2 = 0.06, P = 0.33; Fig.","[3.0, 3.0, 1.0]",Psychology,train,2.333333333333333,tweets,777121306554822656
10.1001/jamapsychiatry.2016.3990,Psychology_tweet_188,Typical #male #brain anatomy associated with higher probability of #autism spectrum disorder. ,"Third, in future research, it will be crucial to further explore the functional relevance of our findings and to examine how normative sexrelated phenotypic diversity in brain structure relates to sex differences in general cognitive or behavioral profiles (eg, as shown by Miller and Halpern 40 and by Hyde 41 ) and to different clinical ASD phenotypes.",Typical #male #brain anatomy associated with higher probability of #autism spectrum disorder. ,"While this scope is sufficient to provide proof of concept, it will be necessary in the future to extend our approach to other neurobiological features that have previously been linked to ASD (eg, cortical surface area and regional volumes 14 ) and to replicate our findings in other subgroups on the autism spectrum (eg, different age groups and individuals with learning disabilities). Third, in future research, it will be crucial to further explore the functional relevance of our findings and to examine how normative sexrelated phenotypic diversity in brain structure relates to sex differences in general cognitive or behavioral profiles (eg, as shown by Miller and Halpern 40 and by Hyde 41 ) and to different clinical ASD phenotypes. Our findings suggest that the neurobiological male phenotype carries a higher intrinsic risk for ASD than the female phenotype across the binary categories dictated by biological sex.","[5.0, 1.0, 2.0, 4.0, 4.0]",Psychology,train,2.0,tweets,829364416919511041
10.1002/hbm.22310,Psychology_tweet_189,fMRI reveals overlapping cortical representations for adjacent fingertips  Wonder if there's less overlap in pianists?,"The interaction between fingertip ROI and stimulation condition was highly significant (F 16,80 5 71.7, P < 10",fMRI reveals overlapping cortical representations for adjacent fingertips  Wonder if there's less overlap in pianists?,"Figure 2C plots the magnitude parameter estimates of the fixed HRF GLM model for each fingertip stimulation condition in each ROI averaged across subjects, confirming this pattern of maximum magnitude estimates for the fingertip stimulation corresponding to the ROI, and significantly larger than baseline responses for up to four adjacent fingertip stimulation conditions. The interaction between fingertip ROI and stimulation condition was highly significant (F 16,80 5 71.7, P < 10 , Greenhouse-Geisser correction: F 1,5 5 71.7, P < 10 23 ).","[3.0, 1.0, 3.0, 4.0, 4.0]",Psychology,train,3.0,tweets,377476005059100672
10.1007/s11031-015-9507-9,Psychology_tweet_19,"Crying first worsens, but then lifts sad mood after a certain time delay.

Background: ","After the initial deterioration of mood following crying that was observed in laboratory studies, it apparently takes some time for the mood, not just to recover, but also to become even less negative than before the emotional event, which corresponds to the results of retrospective studies.","Crying first worsens, but then lifts sad mood after a certain time delay.

Background: ","The observed relation between crying and more long-term mood recovery reconciles seemingly contrasting earlier results and provides a simple and obvious explanation. After the initial deterioration of mood following crying that was observed in laboratory studies, it apparently takes some time for the mood, not just to recover, but also to become even less negative than before the emotional event, which corresponds to the results of retrospective studies. Theories on the functions of crying can be classified into two global categories ( ).","[4.0, 4.0, 5.0, 2.0, 5.0]",Psychology,train,4.0,tweets,635414942242488321
10.1016/j.neuropharm.2017.12.041,Psychology_tweet_190,Lovely to see this appear on PubMed on the last day of the year. Psilocybin works differently to SSRIs to treat depression. The PDF will be coming your way soon 🙂  ,"Indeed, there is evidence of blunting of positive mood with SSRIs .",Lovely to see this appear on PubMed on the last day of the year. Psilocybin works differently to SSRIs to treat depression. The PDF will be coming your way soon 🙂  ,"Relatedly, negative stimuli may be processed as especially salient, and thus be associated with greater amygdala responses e which are subsequently hyper-sensitive to intervention-led change. Indeed, there is evidence of blunting of positive mood with SSRIs . Since the majority of patients reported improvements with the treatment, most answered in the affirmative and described a greater willingness to accept all emotions post-treatment (including negative ones).","[2.0, 3.0, 4.0, 2.0]",Psychology,train,2.75,tweets,947398129032318980
10.1038/nn.3635,Psychology_tweet_192,fMRI/MEG - human object recognition in space and time ,This analysis allows identifying the cortical sources that have persistent neural activity.,fMRI/MEG - human object recognition in space and time ,"Relating MEG and fMRI object signals across time The above MEG-fMRI representational similarity analysis naturally extends to include the MEG time-time decoding matrices constructed earlier (Fig. This analysis allows identifying the cortical sources that have persistent neural activity. We therefore correlated the fMRI dissimilarity matrices of V1 and IT with the MEG 92 × 92 decoding matrices obtained for each pair of time points (t x ,t y ) ( Figs.","[2.0, 2.0, 2.0]",Psychology,train,2.0,tweets,428974506900615168
10.1177/0265407511431185,Psychology_tweet_193,"Sex relieves stress, but only if you're already satisfied with your relationship. JSPR Podcast ","This positive link between the intensity of daily hassles on a given day and the probability of having sexual intercourse on the subsequent day was only significant for women high on relationship satisfaction, g ¼ .26, p ¼ .0024, but not for women low on relationship satisfaction, g ¼ .15, p ¼ .14.","Sex relieves stress, but only if you're already satisfied with your relationship. JSPR Podcast ","Using method to calculate the difference between simple slopes in three-way interactions, we found that for men, the greater the intensity of daily hassles on a given day, the greater the probability of having sexual intercourse on the subsequent day: however, this link was marginally stronger for men low on relationship satisfaction (one standard deviation below the mean of relationship satisfaction; g ¼ .94, p < .001) than for men high on relationship satisfaction (one standard deviation above the mean of relationship satisfaction; g ¼ .40, p ¼ .0075), t(295) ¼ 1.80, p ¼ .07. This positive link between the intensity of daily hassles on a given day and the probability of having sexual intercourse on the subsequent day was only significant for women high on relationship satisfaction, g ¼ .26, p ¼ .0024, but not for women low on relationship satisfaction, g ¼ .15, p ¼ .14. The difference between these slopes, however, was not significant, t(295) ¼ .26, p ¼ .80.","[5.0, 4.0, 2.0, 3.0, 4.0]",Psychology,train,3.6,tweets,319461997987115009
10.1177/2156587216668109,Psychology_tweet_194,"""Tibetan singing bowl meditation ( may be a feasible low-cost technology for reducing feelings of tension, anxiety and depression in individuals who have not previously practiced this form of meditation."" (University of California)
",Feeling of spiritual well-being significantly increased across all participants (P < .001).,"""Tibetan singing bowl meditation ( may be a feasible low-cost technology for reducing feelings of tension, anxiety and depression in individuals who have not previously practiced this form of meditation."" (University of California)
","Additionally, participants who were previously naïve to this type of meditation experienced a significantly greater reduction in tension compared with participants experienced in this meditation (P < .001). Feeling of spiritual well-being significantly increased across all participants (P < .001). Tibetan singing bowl meditation may be a feasible low-cost low technology intervention for reducing feelings of tension, anxiety, and depression, and increasing spiritual well-being.","[5.0, 5.0, 1.0, 4.0, 1.0]",Psychology,train,4.0,tweets,991935650311147520
10.1177/0956797617692041,Psychology_tweet_195,How sugary drink options are presented influence consumption. #psychology #science ,"For the large drink (the only size that the refill manipulation applied to), consumption differed by service style, F(2, 138) = 11.69, p < .001.",How sugary drink options are presented influence consumption. #psychology #science ,"Follow-up tests revealed that for the medium drink, consumption was similar across service styles, F(2, 197) = 1.07, p = .34. For the large drink (the only size that the refill manipulation applied to), consumption differed by service style, F(2, 138) = 11.69, p < .001. Specifically, the participants consumed 51.9% more calories in the waiterservice condition than in the typical-portion condition (waiter-service: M = 210.75 kcal, SD = 83.92; typical portion: M = 138.72 kcal, SD = 37.97), t(93) = 5.33, p < .001, d = 1.09.","[4.0, 5.0, 1.0, 2.0, 3.0]",Psychology,train,4.0,tweets,854412629577617408
10.1093/chemse/bjt066,Psychology_tweet_196,@username Wine labels do matter MT“@username: a rose by other name would smell as sweet? scientists disagree ,"Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis.",@username Wine labels do matter MT“@username: a rose by other name would smell as sweet? scientists disagree ,"These findings further strengthen the concept that odor perception is influenced by cognitive interpretation. Furthermore, we found an impact of labels on intensity ratings for one of the administered odors that goes against our hypothesis. We found that participants rated geraniol as more intense when it was labeled positively (""fresh flowers"") than when labeled negatively (""cheap perfume"").","[4.0, 5.0, 3.0, 2.0, 4.0]",Psychology,train,3.6,tweets,434288870184607744
10.1001/jamapsychiatry.2018.3514,Psychology_tweet_197,Our meta-analysis showing that #psychotic experiences associated with #suicide risk ,"Therefore, command hallucinations to harm oneself may simply reflect underlying suicidal thoughts (as opposed to inducing de novo suicidal thoughts).",Our meta-analysis showing that #psychotic experiences associated with #suicide risk ,"However, the content of hallucinations, including the presence of command hallucinations to harm oneself, cannot be said to emerge at random; rather, hallucination content reflects factors present in the thought content of the affected individual. Therefore, command hallucinations to harm oneself may simply reflect underlying suicidal thoughts (as opposed to inducing de novo suicidal thoughts). 23 It could also be the case that distress associated with PEs increases the risk of suicidal behavior.","[3.0, 4.0, 4.0, 3.0]",Psychology,train,3.5,tweets,1068046045261819904
10.1093/chemse/bjt066,Psychology_tweet_198,a rose by any other name would smell as sweet? odor scientists beg to differ ,"In summary, odor labels affect pleasantness ratings and edibility perception.",a rose by any other name would smell as sweet? odor scientists beg to differ ,"All odorants presented with positive labels were rated as being more pleasant than when they were presented with negative labels. In summary, odor labels affect pleasantness ratings and edibility perception. Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label.","[4.0, 3.0, 4.0, 2.0]",Psychology,train,3.25,tweets,434220518552506368
10.1073/pnas.1505114112,Psychology_tweet_199,"RT @username: Music training can enhance teenage brain development, study suggests  #neurology","Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function.","RT @username: Music training can enhance teenage brain development, study suggests  #neurology","Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years. Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function. The JROTC group exhibited the waning of response consistency characteristically observed between adolescence and young adulthood .","[2.0, 1.0, 3.0, 4.0]",Psychology,train,2.5,tweets,625655559090479105
10.1001/jamaophthalmol.2018.5527,Psychology_tweet_2,From JAMA Ophthalmology:  How does amblyopia influence self-perception in children ages 8 to 13 years?  These results suggest lower self-perception and its association with reading speed and motor skills... ,"Among children with amblyopia, the self-perception of scholastic competence was associated with reading speed, and the self-perception of scholastic, social, and athletic competence was associated with aiming and catching skills.",From JAMA Ophthalmology:  How does amblyopia influence self-perception in children ages 8 to 13 years?  These results suggest lower self-perception and its association with reading speed and motor skills... ,"In this cross-sectional study, children with amblyopia had lower scholastic, social, and athletic competence scores as derived from the Self-perception Profile for Children than control children. Among children with amblyopia, the self-perception of scholastic competence was associated with reading speed, and the self-perception of scholastic, social, and athletic competence was associated with aiming and catching skills. These results suggest lower self-perception and its association with reading speed and motor skills highlight the potentially wide-ranging influence of altered visual development in children in their everyday lives.","[5.0, 5.0, 5.0, 4.0, 5.0]",Psychology,train,4.8,tweets,1064357543827435521
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_20,"Research published in @username identifies brain functional connectivities associated with both sleep and depressive problems, holding great potential for the treatment of depression-related sleep issues. #depression #mentalhealth #brain #sleep ",A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001).,"Research published in @username identifies brain functional connectivities associated with both sleep and depressive problems, holding great potential for the treatment of depression-related sleep issues. #depression #mentalhealth #brain #sleep ","The brain areas with increased functional connectivity associated with both sleep and Depressive Problems scores included the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, anterior and posterior cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus. A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.","[5.0, 4.0, 3.0]",Psychology,train,4.0,tweets,1025381197927669760
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_200,This study may point towards networks that could become targets for intervention for insomnia. ,"We note that only 2 of the 123 items in the Adult Self Report questionnaire, which are used to calculate the Depressive Problems Score, are on the topic of sleep quality, and so these are unlikely to account for the correlations in this study.",This study may point towards networks that could become targets for intervention for insomnia. ,"The correlation was highly significant (r = 0.371; P < .001; Figure 1B ). We note that only 2 of the 123 items in the Adult Self Report questionnaire, which are used to calculate the Depressive Problems Score, are on the topic of sleep quality, and so these are unlikely to account for the correlations in this study. Although participants of the HCP data set were not selected to have a psychiatric disorder and most are healthy control participants, the Depressive Problems raw score was a useful indicator of depression, in that 92 participants who reported having been diagnosed with a major depressive episode also had significantly higher scores on this measure.","[1.0, 2.0, 1.0, 3.0, 2.0]",Psychology,train,1.8,tweets,1153659582725742601
10.1177/0141076814565942,Psychology_tweet_202,"Guidelines suggest #Acetaminophen w/ #circumcision,Cochrane says NO    ",Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96).,"Guidelines suggest #Acetaminophen w/ #circumcision,Cochrane says NO    ",Risk was particularly high for infantile autism before age five years (HR ¼ 2.06; 95% CI: 1.36-3.13). Circumcised boys in non-Muslim families were also more likely to develop hyperkinetic disorder (HR ¼ 1.81; 95% CI: 1.11-2.96). Associations with asthma were consistently inconspicuous (HR ¼ 0.96; 95% CI: 0.84-1.10).,"[1.0, 1.0, 3.0, 1.0]",Psychology,train,1.5,tweets,765245556444631040
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_203,"New study investigates a possible neural basis for the association between depression and poor sleep quality
",This provides evidence that some areas can be associated with depressive symptoms even in individuals who had never been diagnosed with depression.,"New study investigates a possible neural basis for the association between depression and poor sleep quality
","If the 92 participants who had ever been diagnosed with depression were removed from this analysis, the correlations of some of these areas with the Depressive Problems score were still significant, including the anterior cingulate gyrus and middle frontal gyrus (middle frontal gyrus with right anterior cingulate cortex: r = 0.115; P = .001; left cuneus with left superior frontal gyrus, dorsolateral: r = −0.109; P = .002; right inferior parietal gyrus, excluding supramarginal and angular gyri with left middle cingulate and paracingulate gyri: r = 0.059; P = .01; right middle frontal gyrus with left anterior cingulate cortex: r = 0.059; P = .01; left postcentral gyrus with left inferior temporal lobe: r = 0.059; P = .01; eTable 2 in the Supplement). This provides evidence that some areas can be associated with depressive symptoms even in individuals who had never been diagnosed with depression. However, all of the links involving the lateral orbitofrontal cortex became nonsignificant if this subgroup of 92 individuals was removed (eTable 3 in the Supplement).","[4.0, 1.0, 2.0, 2.0, 2.0]",Psychology,train,2.2,tweets,1023818008194686976
10.1016/j.jpeds.2017.10.028,Psychology_tweet_204,Don't #spank your children. Full stop. The Journal of Pediatrics on the relationship between corporal punishment and perpetration of future #datingviolence: ,"There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .",Don't #spank your children. Full stop. The Journal of Pediatrics on the relationship between corporal punishment and perpetration of future #datingviolence: ,"Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","[2.0, 4.0, 2.0]",Psychology,train,2.6666666666666665,tweets,941407958386249733
10.1016/j.jpeds.2017.10.028,Psychology_tweet_205," Spanking your child may have unintended consequences as he or she forges adult romantic relationships years later, a new study suggests. The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researche… ","Second, in contrast to past research, no differences in corporal punishment were found when stratified by demographic characteristics."," Spanking your child may have unintended consequences as he or she forges adult romantic relationships years later, a new study suggests. The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researche… ","First, more than one-half (68%) of participants in this sample reported experiencing corporal punishment as children. Second, in contrast to past research, no differences in corporal punishment were found when stratified by demographic characteristics. Third, consistent with extant literature, female subjects were more likely to perpetrate teen dating violence than their male counterparts.","[1.0, 2.0, 1.0, 2.0, 1.0]",Psychology,train,1.4,tweets,938150354264477696
10.1016/j.jpeds.2017.10.028,Psychology_tweet_206,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22. A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59).","[2.0, 3.0, 2.0, 2.0]",Psychology,train,2.25,tweets,946221697962774528
10.1016/j.jpeds.2017.10.028,Psychology_tweet_207,"@username It took like 5 secs of Googling to find this. And the whole research and practitioner narrative of abusive relationships is about intergenerational transmissibility of violence. Hurt people hurt people, etc.   ","The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","@username It took like 5 secs of Googling to find this. And the whole research and practitioner narrative of abusive relationships is about intergenerational transmissibility of violence. Hurt people hurt people, etc.   ","Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment. (J Pediatr 2018;194:233-7).","[4.0, 3.0, 4.0, 3.0, 2.0]",Psychology,train,3.2,tweets,944452687478820864
10.1177/1948550617750737,Psychology_tweet_208,NEW PAPER: Disillusionment leads people to endorse more extreme political views. Our research shows that disillusionment in the wake of #Trump and #Brexit led to political polarization:  #disillusionment #SPPS @username @username @username ,"To halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed.",NEW PAPER: Disillusionment leads people to endorse more extreme political views. Our research shows that disillusionment in the wake of #Trump and #Brexit led to political polarization:  #disillusionment #SPPS @username @username @username ,"Our research provides evidence of disillusionment-induced political polarization, using naturalistic quasi-experimental and experimental designs. These intriguing findings advance insights into the effects of disillusionment and the important practical implications of this experience. To halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed.","[1.0, 3.0, 5.0, 5.0]",Psychology,train,3.0,tweets,953585353654439936
10.1186/s13229-018-0246-0,Psychology_tweet_209,"Unsurprisingly, research shows that the #autism prevalence in China is similar to the autism prevalence in the US and UK:

 #Neurodiversity","In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000.","Unsurprisingly, research shows that the #autism prevalence in China is similar to the autism prevalence in the US and UK:

 #Neurodiversity","In Shenzhen, it was 42.3 per 10,000 and 19.0 per 10,000 in Jiamusi. In Jilin, where prevalence included those children with autism identified from special education and other settings outside mainstream population, the prevalence estimate was 108 per 10,000. The strengths of this first large-scale study of autism in China are several.","[1.0, 5.0, 4.0, 3.0, 3.0]",Psychology,train,3.0,tweets,1114713942238973953
10.1001/jamapsychiatry.2018.3514,Psychology_tweet_21,"Here’s our latest on psychotic experiences (PE) &amp;suicide.

Big pic: PE are clinically important! They predict ⬆️⬆️⬆️ risk of attempted &amp;completed suicide (beyond what’s explained by co-occurring mental illness).
#SystematicReview
@username 
 ","Individuals who reported PEs had a 4.39-fold (95% CI, 1.63-11.78) increased odds of suicide death (Figure 2 ).","Here’s our latest on psychotic experiences (PE) &amp;suicide.

Big pic: PE are clinically important! They predict ⬆️⬆️⬆️ risk of attempted &amp;completed suicide (beyond what’s explained by co-occurring mental illness).
#SystematicReview
@username 
 ","Individuals who reported PEs had a 3.15-fold (95% CI, 2.23-4.45) increased odds of suicide attempt. Individuals who reported PEs had a 4.39-fold (95% CI, 1.63-11.78) increased odds of suicide death (Figure 2 ). The population-attributable fraction of PEs for suicidal ideation was 11.9%.","[4.0, 5.0, 4.0]",Psychology,train,4.333333333333333,tweets,1067812750905286656
10.1007/s11482-009-9091-9,Psychology_tweet_210,Vacations may be more pleasurable to plan and anticipate than to remember. ,"This study demonstrates that vacationers are happier, compared to non-vacationers, but a holiday trip does not add much to their happiness.",Vacations may be more pleasurable to plan and anticipate than to remember. ,"Holiday expectation ) and homesickness could be assessed for possible moderating effects. This study demonstrates that vacationers are happier, compared to non-vacationers, but a holiday trip does not add much to their happiness. Generally, there were no differences between vacationers' and non-vacationers' post-trip happiness.","[3.0, 4.0, 2.0, 2.0]",Psychology,train,2.75,tweets,409013906560917506
10.1177/2158244019828850,Psychology_tweet_211,"""We establish here that even a medium as apparently unpromising as Twitter is full of complex, extended political conversations.""  ","Using data from Facebook and Wikipedia, find the identities of recent commenters is most predictive of conversation reentry.","""We establish here that even a medium as apparently unpromising as Twitter is full of complex, extended political conversations.""  ","Supporting this theory, find that the number of distinct users in long threads follows a bimodal distribution. Using data from Facebook and Wikipedia, find the identities of recent commenters is most predictive of conversation reentry. This lattermost line of work is largely a-theoretical and not particularly concerned with normative issues.","[2.0, 1.0, 3.0]",Psychology,train,2.0,tweets,1111155732760707073
10.1037/a0026545,Psychology_tweet_212,"memo: Everyday temptations: An experience sampling study of desire, ... (Journal of Personality and Social Psychology) ","Our findings suggest that desire is a common, recurrent theme in daily life.","memo: Everyday temptations: An experience sampling study of desire, ... (Journal of Personality and Social Psychology) ","To our knowledge, this investigation is the first systematic attempt to provide empirical evidence about such basic questions as the prevalence of desire and conflict in everyday life and the frequency and effectiveness of self-control efforts to resist desire. Our findings suggest that desire is a common, recurrent theme in daily life. Frequent inner struggle to manage desire is another theme.","[3.0, 3.0, 3.0, 5.0, 2.0]",Psychology,train,3.2,tweets,147367692591054848
10.1073/pnas.1510456112,Psychology_tweet_215,Science takes a long time; here's my dissertation work on FGF9 in #depression published today @username:  #goblue,"Specifically, FGF2 expression was reduced and FGF9 expression was elevated in the frontal cortices (3) and locus coeruleus (4) of the depressed brain relative to controls.",Science takes a long time; here's my dissertation work on FGF9 in #depression published today @username:  #goblue,"We uncovered a significant negative correlation between hippocampal FGF9 expression and FGF2 expression in postmortem hippocampal tissue, and this relationship may indicate that these transcripts work in functional opposition. Specifically, FGF2 expression was reduced and FGF9 expression was elevated in the frontal cortices (3) and locus coeruleus (4) of the depressed brain relative to controls. The negative correlations between FGF9 expression and other FGFs also underscore the biological significance of FGF9 dysregulation in affective disorders: these relationships indicate that FGF9 may be acting in a complex network of molecules, and the alterations in FGF9 expression are concurrent with changes in other FGF family members that we have previously observed to impact affective behavior.","[2.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,3.0,tweets,641347320395657216
10.1177/0001839213509590,Psychology_tweet_217,Why is it good to enter the workforce in a time of recession? ,"Across three studies, well-educated graduates who entered the workforce during economic downturns were more satisfied with their current jobs than those who entered during more prosperous economic times.",Why is it good to enter the workforce in a time of recession? ,"Across three studies, well-educated graduates who entered the workforce during economic downturns were more satisfied with their current jobs than those who entered during more prosperous economic times. Study 1 showed that economic conditions at college graduation predicted later job satisfaction even after accounting for different industry and occupational choices. Study 2 replicated these results and found that recession-era graduates were more satisfied with their jobs both early and later in their careers and even when they earned less money.","[5.0, 5.0, 3.0, 4.0]",Psychology,train,4.25,tweets,391973059772436480
10.1177/0885412206295846,Psychology_tweet_218,A closer look at public toilets: perspective piece on public restrooms and gender issues ,"They call for an end to urinal troughs in men's restrooms, greater space between urinals, the construction of floor-to-ceiling partitions between urinals, and doors on all toilet stalls.",A closer look at public toilets: perspective piece on public restrooms and gender issues ,"Soifer argued that some boys become targets for bullying-not perceived as being ""manly"" enough to stand up, show their equipment, and use a urinal-merely by entering a toilet cubicle. They call for an end to urinal troughs in men's restrooms, greater space between urinals, the construction of floor-to-ceiling partitions between urinals, and doors on all toilet stalls. Soifer also recommended a white noise device such as a fan to help users feel more comfortable.","[2.0, 4.0, 4.0, 2.0]",Psychology,train,3.0,tweets,717412168187179009
10.1038/tp.2013.50,Psychology_tweet_219,Autism: mothers autoantibodies target critical proteins in developing brain ,"In addition, although no significant differences in subscale or composite scores were noted for the Mullen Scales of Early Learning or the Vineland Adaptive Behavioral Scales, increased impairments in the stereotypical behavior subscale of the ABC were observed for children of mothers possessing antibodies reactive to LDH in any context (P ¼ 0.024), CRMP1 (trending toward significance; P ¼ 0.055), as well as combined reactivity to LDH and STIP1 (P ¼ 0.015), or LDH/STIP1/CRMP1 (P ¼ 0.007) in comparison to children with an ASD whose mothers lack IgG reactivity to these antigens.",Autism: mothers autoantibodies target critical proteins in developing brain ,"We also analyzed the Autism Diagnostic Observation Schedule and Social Communication Questionnaire behavior scales in the ASD group, but there were no significant associations found with any of the band patterns. In addition, although no significant differences in subscale or composite scores were noted for the Mullen Scales of Early Learning or the Vineland Adaptive Behavioral Scales, increased impairments in the stereotypical behavior subscale of the ABC were observed for children of mothers possessing antibodies reactive to LDH in any context (P ¼ 0.024), CRMP1 (trending toward significance; P ¼ 0.055), as well as combined reactivity to LDH and STIP1 (P ¼ 0.015), or LDH/STIP1/CRMP1 (P ¼ 0.007) in comparison to children with an ASD whose mothers lack IgG reactivity to these antigens. In addition, increased overall impairment was reflected in the composite ABC score for children of mothers reactive against LDH and CRMP1 (P ¼ 0.046) as well as LDH/STIP1/CRMP1 (trending toward significance; P ¼ 0.06).","[4.0, 4.0, 3.0, 1.0, 1.0]",Psychology,train,3.0,tweets,356022646988742656
10.1016/j.cub.2011.12.018,Psychology_tweet_220,Dog's gaze following tuned to human communicative signals: ,"Furthermore, dogs followed the actor's gaze significantly less in the BC compared to the O condition [cumulative accuracy, two-sample t test, t(24) = 22.107, p = 0.045].",Dog's gaze following tuned to human communicative signals: ,"Importantly, however, the accuracy indexes calculated for the cueing phase did not capture gaze following in BC [mean 6 SEM of cumulative accuracy: 20.06 6 0.14; one-sample t test, t(12) = 20.433; p = 0.67; first look: 0.11 6 0.16; one-sample t test, t(12) = 0.695; p = 0.5]. Furthermore, dogs followed the actor's gaze significantly less in the BC compared to the O condition [cumulative accuracy, two-sample t test, t(24) = 22.107, p = 0.045]. These data suggest that the lack of gaze following, when there are no ostensive signals, cannot be accounted for by the confounding effect of ''artificial'' salient attention getter used in the NO condition, also providing further support for the significant role of ostensive signals in dogs' gaze response.","[5.0, 5.0, 3.0, 3.0, 4.0]",Psychology,train,4.0,tweets,159447747328618496
10.1111/risa.12369,Psychology_tweet_221,@username Two papers on adolescent and adult risk taking online  and  #CyberShare,"Developing and imparting more gist based knowledge, in order to engage more intuitive thinking about online risk-taking, may well help to protect young people against some of the dangers involved in certain online activities.",@username Two papers on adolescent and adult risk taking online  and  #CyberShare,"Certainly, since risk prevention messages have been shown to be effectively communicated via social networking sites communication of risk in an online environment about online risk is an area warranting further investigation. Developing and imparting more gist based knowledge, in order to engage more intuitive thinking about online risk-taking, may well help to protect young people against some of the dangers involved in certain online activities. Further research on young people's online risk taking will not only help identify the decision making processes involved when making risky decisions about online activities, but also help develop more effective education strategies that can encourage young people to reap the benefits of the virtual world while also protecting them against potential threat.","[4.0, 3.0, 2.0, 3.0, 2.0]",Psychology,train,2.8,tweets,862362268289388544
10.1016/j.eurpsy.2018.06.006,Psychology_tweet_222,Very important article: Early life experiences and social cognition in major psychiatric disorders ,This remains a priority for future research that seeks to model the relationship between early adversity and genetic risk in contribution to social cognitive development.,Very important article: Early life experiences and social cognition in major psychiatric disorders ,"). This remains a priority for future research that seeks to model the relationship between early adversity and genetic risk in contribution to social cognitive development. Furthermore, there is some evidence that this relationship may be conditional on genetic variation at the 5-HTT locus .","[2.0, 2.0, 3.0, 4.0]",Psychology,train,2.75,tweets,1088387393575665664
10.1007/s40279-018-0916-2,Psychology_tweet_223,"...based on the empirical evidence currently available, active cool-downs are largely ineffective... ","An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter.","...based on the empirical evidence currently available, active cool-downs are largely ineffective... ","Strategies that enhance the resynthesis of glycogen may therefore attenuate the decrease in performance and even enhance performance. An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter. Therefore, these findings suggest that an active cool-down may interfere with muscle glycogen resynthesis, particularly within type I muscle fibers , because these fibers are preferentially recruited during a low-to moderate-intensity active cool-down.","[1.0, 2.0, 2.0, 4.0]",Psychology,train,2.25,tweets,986466226842062849
10.1038/s41562-018-0483-4,Psychology_tweet_224,"The impact of learning one's genetic risk for a disease on an individual's perception and physiology. Interesting experiments to probe this issue.
 @username
by  @username @username and colleagues @username ","While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype.","The impact of learning one's genetic risk for a disease on an individual's perception and physiology. Interesting experiments to probe this issue.
 @username
by  @username @username and colleagues @username ","The information itself provides a distinct psychological framework through which the individual interprets their current experience and prepares for future experiences and, as a result, this new mindset influences attention, motivation and, most interestingly, physiology in a manner that confirms their expectations 52 . While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype. Whether perceived risk elicits a negative effect or perceived protection elicits a positive effect is likely to differ depending on the gene of interest and the experimental paradigm.","[2.0, 3.0, 4.0, 4.0]",Psychology,train,3.25,tweets,1072164604065701889
10.1073/pnas.1816076116,Psychology_tweet_225,"The mixed effects of online #diversity training
via @username

#diversitytraining ","On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training.","The mixed effects of online #diversity training
via @username

#diversitytraining ","Among groups whose average untreated attitudes-whereas still supportive of women-were relatively less supportive of women than other groups, our diversity training successfully produced attitude change but not behavior change. On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training. This paper extends our knowledge about the pathways to attitude and behavior change in the context of bias reduction.","[4.0, 2.0, 3.0, 3.0]",Psychology,train,3.0,tweets,1112795255743700992
10.1073/pnas.1816581115,Psychology_tweet_226,"Excited about my first publication in my new lab, in which we show that people generate subconscious models of other people's attention as a force-carrying ""beam"" projecting from the eyes (which is actually how most kids believe vision works) #eyebeamsrule ","Participants showed a significant bias that, in our interpretation, indicates an implicit belief in an invisible force that emanates from the eyes and mechanically pushes on objects.","Excited about my first publication in my new lab, in which we show that people generate subconscious models of other people's attention as a force-carrying ""beam"" projecting from the eyes (which is actually how most kids believe vision works) #eyebeamsrule ","It may depend on automatic, implicit models about gaze that are robust against intellectual knowledge . Participants showed a significant bias that, in our interpretation, indicates an implicit belief in an invisible force that emanates from the eyes and mechanically pushes on objects. The implied force was small in magnitude, corresponding to about a hundredth of a newton, comparable to a light puff of air.","[5.0, 2.0, 4.0, 3.0, 2.0]",Psychology,train,3.2,tweets,1074766403314614273
10.1176/appi.ajp.2018.17111282,Psychology_tweet_227,"Implementating #pharmacogenetic decision support tools for #antidepressant #prescribing: 
Evidence is suboptimal, but better perhaps at predicting #sideeffects ",Identifying genetic variants with the greatest empirical support is critical for evaluating and implementing combinatorial pharmacogenetic testing.,"Implementating #pharmacogenetic decision support tools for #antidepressant #prescribing: 
Evidence is suboptimal, but better perhaps at predicting #sideeffects ","Conversely, knowledge that a patient's genotype predicted poor metabolism by the enzymes regulating pharmacokinetics of a candidate medication might portend tolerability problems even at low dosages and perhaps prompt a prescriber to use a very low dosage or to avoid that agent altogether. Identifying genetic variants with the greatest empirical support is critical for evaluating and implementing combinatorial pharmacogenetic testing. The PharmGKB level-of-evidence scale for gene-drug interactions ranges from preliminary evidence of association (level 4) to significant associations with strong effect sizes that have been replicated in multiple cohorts (level 1A).","[3.0, 2.0, 1.0, 2.0, 2.0]",Psychology,train,2.0,tweets,989143622250614785
10.1177/0305735611430081,Psychology_tweet_229,"from the journal Psychology of Music, the benefits of choir singing for the mentally ill: ","Participation in a choir or other group activity can increase their level of social interaction and potentially provide an additional social identity, which could have positive outcomes for their health and well being.","from the journal Psychology of Music, the benefits of choir singing for the mentally ill: ","This research is particularly relevant for disadvantaged people -many of whom live in social isolation. Participation in a choir or other group activity can increase their level of social interaction and potentially provide an additional social identity, which could have positive outcomes for their health and well being. The IPA approach has been called the most psychological of the thematic analysis approaches, with a particular focus on the cognitions and emotions of participants , which makes it a suitable approach for the current study.","[4.0, 4.0, 4.0, 3.0]",Psychology,train,3.75,tweets,179657471420407808
10.1073/pnas.1508932113,Psychology_tweet_230,It's not really manspreading. Expansive posture increases desirability consistent across gender. @username  ,"These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success.",It's not really manspreading. Expansive posture increases desirability consistent across gender. @username  ,"Specifically, perceivers' impressions of a target's dominance increase significantly as the target assumes a more expanded and open nonverbal posture . These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success. * Given its link to resource acquisition, possession, and allocation control/sharing, the functional preference for dominance in mates may have emerged because it is linked to one's own longer life span as well as to reproductive success and offspring survival.","[2.0, 5.0, 5.0, 2.0, 1.0]",Psychology,train,4.0,tweets,714712272699072512
10.1007/s11031-018-9698-y,Psychology_tweet_231,Please check out and share our meta-analysis on leader autonomy support  @username @username @username @username @username,"Overall, our findings lend support for autonomy support as a leadership approach that is consistent with self-determination and optimal functioning in work settings.",Please check out and share our meta-analysis on leader autonomy support  @username @username @username @username @username,"In addition, a meta-analytic path analysis supported motivational processes that underlie LAS and its consequences in workplaces. Overall, our findings lend support for autonomy support as a leadership approach that is consistent with self-determination and optimal functioning in work settings. LAS is characterized by leaders who take interest in the perspectives of their employees, provide opportunities for choice and input, encourage self-initiation, and avoid the use of external rewards or sanctions to motivate behavior.","[3.0, 3.0, 3.0, 1.0]",Psychology,train,2.5,tweets,997018704704557056
10.1098/rspb.2013.1724,Psychology_tweet_232,Is it harder to lead or to follow? Proceedings of the Royal Society B: Biological Sciences  ,"However, we did find that, for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow.",Is it harder to lead or to follow? Proceedings of the Royal Society B: Biological Sciences  ,"Contradicting the predictions outlined in the Introduction , we did not find any difference in the adaptability of bold and shy individuals to changes in leadership. However, we did find that, for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow. The tendency to initiate trips differed only between treatments by 27% in bold and 46% in shy fish (figure 3a; q 12 /q In summary, fish (whether bold or shy) can easily learn to follow, but they cannot easily learn to lead.","[3.0, 3.0, 2.0, 2.0]",Psychology,train,2.5,tweets,372668643991363584
10.1007/s11121-017-0762-8,Psychology_tweet_233,Past-Year #SexualAssault Victimization among Undergrads: Diff by Gender &amp; Sexual Identity &amp; Race/Ethnicity [a]  #Rape,"Transgender people had higher odds of sexual assault than cisgender men and women, and Black transgender people had significantly higher odds of sexual assault than White transgender people.",Past-Year #SexualAssault Victimization among Undergrads: Diff by Gender &amp; Sexual Identity &amp; Race/Ethnicity [a]  #Rape,"Our exploratory results indicated that sexual assault disproportionately affects several sexual, gender, and racial/ethnic minority subgroups. Transgender people had higher odds of sexual assault than cisgender men and women, and Black transgender people had significantly higher odds of sexual assault than White transgender people. Like in previous studies (American College Health Association 2012 , cisgender women had higher odds of sexual assault than cisgender men, but gender modified the effects of sexual identity and race/ethnicity on sexual assault.","[2.0, 3.0, 2.0, 3.0]",Psychology,train,2.5,tweets,853737324462657536
10.1073/pnas.1517057112,Psychology_tweet_234,People low in power are significantly more trusting than powerful people ,"Power-disadvantaged actors thus effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions.",People low in power are significantly more trusting than powerful people ,"In particular, with increasing dependence, people will be motivated to see their partner as more trustworthy to avoid the anxiety inherently attached to their feelings of dependence. Power-disadvantaged actors thus effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions. Using different experimental paradigms and measures and confirming predictions based on motivated cognition theory, we show that people low in power are significantly more trusting than more powerful people and that this effect can be explained by the constructs of hope and perceived benevolence.","[3.0, 2.0, 2.0, 2.0]",Psychology,train,2.25,tweets,651280515329339392
10.1073/pnas.1512653112,Psychology_tweet_235,Swiss researchers link anxiety to social status in rats--and finds vitamin B3 reduces anxiety/boosts status ,Here we show that trait anxiety directly influences social dominance in male outbred rats and identify an important mediating role for mitochondrial function in the nucleus accumbens.,Swiss researchers link anxiety to social status in rats--and finds vitamin B3 reduces anxiety/boosts status ,Here we show that trait anxiety directly influences social dominance in male outbred rats and identify an important mediating role for mitochondrial function in the nucleus accumbens. High-anxious animals that are prone to become subordinate during a social encounter with a low-anxious rat exhibit reduced mitochondrial complex I and II proteins and respiratory capacity as well as decreased ATP and increased ROS production in the nucleus accumbens. A causal link for these findings is indicated by pharmacological approaches.,"[3.0, 2.0, 4.0, 2.0]",Psychology,train,2.75,tweets,671535559689547776
10.1007/s13524-014-0321-x,Psychology_tweet_236,“...up to two children increases happiness...” Oops. 🤷🏻‍♂️🤣 ,"Those who have children at older ages or who have more education have a particularly positive happiness response to a first birth; and although having the first two children increases happiness, having a third child does not.",“...up to two children increases happiness...” Oops. 🤷🏻‍♂️🤣 ,"Sociodemographic factors strongly modify this pattern. Those who have children at older ages or who have more education have a particularly positive happiness response to a first birth; and although having the first two children increases happiness, having a third child does not. The results, which are similar in Britain and Germany, suggest that having up to two children increases happiness, and mostly for those who have postponed childbearing.","[4.0, 4.0, 3.0]",Psychology,train,3.6666666666666665,tweets,1162854429512441856
10.1093/schbul/sbv109,Psychology_tweet_237,Analysis of #schizophrenia across different ethnic groups: ,This would provide evidence for a neuroanatomical signature of schizophrenia expressed above and beyond ethnic differences in incidence and clinical expression.,Analysis of #schizophrenia across different ethnic groups: ,"As the 4 groups were scanned at different sites using different scanners and acquisition sequences (see supplementary table S1 for detail), any discrepancy between datasets could be due to methodological differences. This would provide evidence for a neuroanatomical signature of schizophrenia expressed above and beyond ethnic differences in incidence and clinical expression. All patients in the Chinese sample were medication naïve at the time of scanning; in contrast, patients in the White Caucasian, African-Caribbean and Japanese samples were taking first-or second-generation antipsychotic medication, or a combination of the two (see table 1 for chlorpromazineequivalent dose).","[4.0, 4.0, 4.0, 2.0]",Psychology,train,3.5,tweets,648253373758709762
10.1111/acer.12200,Psychology_tweet_239,"Men over-state, while women under-state, drunkenness: their own and other peoples'  In a college student sample. Hmmm.",Conclusions: The findings suggest that gender differences in the application of intoxication terms are other-directed as well as self-directed and that intoxication language can inform gender-specific prevention and intervention efforts targeting problematic alcohol use among college students.,"Men over-state, while women under-state, drunkenness: their own and other peoples'  In a college student sample. Hmmm.","Specifically, moderate intoxication terms were applied to and from women more than men, even when the character was heavily intoxicated, whereas heavy intoxication terms were applied to and from men more than women. Conclusions: The findings suggest that gender differences in the application of intoxication terms are other-directed as well as self-directed and that intoxication language can inform gender-specific prevention and intervention efforts targeting problematic alcohol use among college students. Understanding this language can provide critical insight into subjective perceptions of intoxicated states, particularly among specific groups in the general drinking population such as college students that demonstrate elevated levels of heavy episodic drinking and alcohol-related consequences.","[4.0, 5.0, 4.0, 3.0]",Psychology,train,4.0,tweets,356073305180082176
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_24,Is it possible to identify brain functional connectivities that mediate the association of #depressive problems with poor #sleep quality and advance understanding of brain functional connectivity associated with depressive problems score? Find out  ,"Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig.",Is it possible to identify brain functional connectivities that mediate the association of #depressive problems with poor #sleep quality and advance understanding of brain functional connectivity associated with depressive problems score? Find out  ,"In the reverse direction, only 2 links significantly mediated effects of sleep quality on depressive problems with FDR correction. Further, the mediating effects of the 39 functional connectivities of the effects of the sleep quality on the depressive problems had much lower significance (3.4% of the total effect size, =0.016, p=0.0095, Fig. S4 ) than for the effect in the opposite direction described above.","[4.0, 4.0, 3.0, 2.0]",Psychology,train,3.25,tweets,1022602476846047232
10.1007/s10071-013-0699-7,Psychology_tweet_240, Dissociation of visual localization and visual detection in rhesus monkeys #neuroscience #psychology #AnimalCognition,"Instead, the monkeys did not perceive the target and reported that.", Dissociation of visual localization and visual detection in rhesus monkeys #neuroscience #psychology #AnimalCognition,"This shows that the monkeys were not responding randomly due to increased difficulty. Instead, the monkeys did not perceive the target and reported that. Neither the main effect of SOA nor the interaction of SOA and task was significant (SOA: F 5,44 = 1.24, P = 0.31; SOA x task: F 5,44 = 0.74, P = 0.60), which is consistent with the hypothesis that monkeys solved the task in the same manner across all SOAs.","[2.0, 1.0, 4.0, 3.0]",Psychology,train,2.5,tweets,409691534872018944
10.1126/science.1238677,Psychology_tweet_241,Evolution's explanation of monogamy: [paraphrase: females don't like each other and males can only defend one female] ,"About half of all independent transitions to paternal care have occurred in instances where social monogamy was already established, whereas the evolution of paternal care occurred on the same branch as a transition to social monogamy in the other cases.",Evolution's explanation of monogamy: [paraphrase: females don't like each other and males can only defend one female] ,"Although paternal care and social monogamy are associated, an analysis of transitions suggests that male care is probably a consequence rather than a cause of the evolution of social monogamy. About half of all independent transitions to paternal care have occurred in instances where social monogamy was already established, whereas the evolution of paternal care occurred on the same branch as a transition to social monogamy in the other cases. Inferences from BayesTraits' models indicate that paternal care is a secondary adaptation, because transitions to social monogamy are inferred to occur first on branches where both traits evolved separately (lrt P = 0.002; table S2).","[5.0, 2.0, 2.0, 1.0]",Psychology,train,2.0,tweets,362272337753677824
10.1093/qje/qjr001,Psychology_tweet_242,.@username a U.S. study shows similar findings when examining unexpected outcomes of american football games ,"Of these games, 316 (36%) were predicted wins for the home team, 245 (28%) were predicted losses, and 305 (35%) were predicted close games.",.@username a U.S. study shows similar findings when examining unexpected outcomes of american football games ,"For ""predicted losses"" (spread > 3) the probability of a win is 41% or less. Of these games, 316 (36%) were predicted wins for the home team, 245 (28%) were predicted losses, and 305 (35%) were predicted close games. The greater number of predicted wins than losses reflects the inclusion in our sample of two relatively successful teams (Denver and New England).","[2.0, 4.0, 3.0, 2.0]",Psychology,train,2.75,tweets,538388613449650176
10.1073/pnas.1612233114,Psychology_tweet_243,"Dopamine plays a role in mediating the affiliative, prosocial affects of synchrony  @username @username","Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted.","Dopamine plays a role in mediating the affiliative, prosocial affects of synchrony  @username @username","Together, these data indicate that dopamine is involved in human bonding. Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted. Mothers who were sensitive to their infants' cues for social engagement and who adjusted their own behavior to meet those needs (referred to as ""mother-infant synchrony""), showed greater activations in the left NAcc and lower activation in the right amygdala when viewing films of their infants than did nonsynchronous mothers (4).","[2.0, 3.0, 1.0, 5.0, 1.0]",Psychology,train,2.0,tweets,831239089357721605
10.1073/pnas.1421304111,Psychology_tweet_244,Learning requires BOTH neuromodulation and Hebbian plasticity. Directly measured in rats. ,An intriguing question raised by these results is how β-AR activation in the LA modulates Hebbian processes and synaptic plasticity in this small cell population to produce threat learning.,Learning requires BOTH neuromodulation and Hebbian plasticity. Directly measured in rats. ,"Thus, other factors such as the availability or levels of intracellular signaling molecules, local competition between cell assemblies, or the availability of auditory CS inputs to a given cell may have played a role in allocation of plasticity to a small proportion of the stimulated neurons ( . An intriguing question raised by these results is how β-AR activation in the LA modulates Hebbian processes and synaptic plasticity in this small cell population to produce threat learning. However, in addition to being expressed in glutamatergic neurons in LA, β-ARs are also expressed in presynaptic inputs to these neurons and in GABAergic and astrocytic cells .","[5.0, 3.0, 2.0, 2.0]",Psychology,train,3.0,tweets,552578044930834432
10.1111/cdev.12313,Psychology_tweet_245,Having controlling parents may affect later relationships ,"Greater autonomy and relatedness with close friends at age 13 significantly predicted greater autonomy and relatedness with romantic partners 5 years later, at age 18.",Having controlling parents may affect later relationships ,"Figure 2 illustrates significant cross-over cascade pathways between autonomy and relatedness with partners and friends. Greater autonomy and relatedness with close friends at age 13 significantly predicted greater autonomy and relatedness with romantic partners 5 years later, at age 18. In addition, age 18 autonomy and relatedness with close friends predicted relative increases (controlling for baseline levels) in autonomy and relatedness with romantic partners between ages 18 and 21.","[1.0, 3.0, 2.0, 3.0, 1.0]",Psychology,train,2.0,tweets,527778278590124032
10.1177/0956797616672268,Psychology_tweet_246,"An interesting finding—misinformation for memorable details might enhance, not impair, memory. New in @username ","In a striking experiment, showed just how important noticing change can be for preventing misinformation effects.","An interesting finding—misinformation for memorable details might enhance, not impair, memory. New in @username ","did not measure change detection directly, but reading times and postexperiment interviews of the subjects corroborated the discrepancy-detection principle, which predicts that noticing discrepancies substantially reduces misinformation effects. In a striking experiment, showed just how important noticing change can be for preventing misinformation effects. Critically, the fifth piece of misinformation was a blatant change that every subject was 672268P SSXXX10.1177/0956797616672268Misinformation and RemindingsPutnam et al.","[3.0, 3.0, 2.0, 5.0, 2.0]",Psychology,train,3.0,tweets,801384985827639296
10.1089/cap.2018.0030,Psychology_tweet_247,Small OL study in adolescents with TRD treated with IV ketamine: Average decrease in CDRS-R was 42.5% (p = 0.0004). Five (38%) adolescents met criteria for clinical response. Ketamine infusions were generally well tolerated ,The low attrition for treatment visits and the first posttreatment clinical assessment could reflect strong commitment to the study from patients and parents based on their intimate knowledge of the importance of research investigating new treatments for adolescent TRD.,Small OL study in adolescents with TRD treated with IV ketamine: Average decrease in CDRS-R was 42.5% (p = 0.0004). Five (38%) adolescents met criteria for clinical response. Ketamine infusions were generally well tolerated ,"This is somewhat surprising given the presence of some adverse events as noted above, especially for those adolescents that showed no clinical improvement throughout the study. The low attrition for treatment visits and the first posttreatment clinical assessment could reflect strong commitment to the study from patients and parents based on their intimate knowledge of the importance of research investigating new treatments for adolescent TRD. It could also reflect hopes and expectations on the part of patients and families for what ketamine treatment could deliver, based on the reports around that time in public media avenues on the promise of ketamine for depression.","[2.0, 2.0, 3.0]",Psychology,train,2.333333333333333,tweets,1021897020875960321
10.1016/j.sleh.2018.09.005,Psychology_tweet_249,"Make sure you get enough sleep before a big game...

",Twitter data may provide sleep and sports researchers with a new tool to examine the effects of late-night activity on a variety of outcome measures.,"Make sure you get enough sleep before a big game...

","In summary, we have demonstrated a negative association between late-night tweeting and player outputs among professional athletes in the high-stakes, competitive environment of official NBA games. These findings may apply widely to other sports and other cognitive and behavioral outcomes. Twitter data may provide sleep and sports researchers with a new tool to examine the effects of late-night activity on a variety of outcome measures.","[3.0, 4.0, 3.0, 4.0, 2.0]",Psychology,train,3.2,tweets,1064467873752641537
10.1001/jamapsychiatry.2013.4081,Psychology_tweet_25,Kids of younger and older parents are at increased risk for mental disorders. Age 25-29 is the sweet spot. Get goin'! ,"Compared with the offspring of mothers aged 25 to 29 years, the offspring of mothers aged 12 to 19 years had a 51% increased risk of having a mental disorder (IRR, 1.51 [95% CI, 1.48-1.54]).",Kids of younger and older parents are at increased risk for mental disorders. Age 25-29 is the sweet spot. Get goin'! ,"Considering the broadest category of any psychiatric diagnosis (ICD-10-DCR codes F00-F99) as the outcome of interest, the offspring of the youngest mothers were at the highest risk for any mental disorders. Compared with the offspring of mothers aged 25 to 29 years, the offspring of mothers aged 12 to 19 years had a 51% increased risk of having a mental disorder (IRR, 1.51 [95% CI, 1.48-1.54]). No significantly increased risk for the offspring of older mothers was found.","[4.0, 4.0, 4.0, 5.0, 5.0]",Psychology,train,4.4,tweets,426117864307695616
10.1177/0956797614568318,Psychology_tweet_251,"new study finds ""a personal mission to transform suffering into positive outcomes"" assoc w/well-being mid-life: ","Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years.","new study finds ""a personal mission to transform suffering into positive outcomes"" assoc w/well-being mid-life: ","The same kind of life story is also associated with increased levels of public-service motivation and psychological well-being but is unrelated to depression. Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years. Finally, two well-validated narrative constructs that are not part of the redemptive-self pattern-contamination sequences and meaning making-appeared to be unrelated to levels of psychosocial adaptation at midlife, with the exception of a modest association between contamination sequences and depression.","[2.0, 1.0, 2.0, 1.0]",Psychology,train,1.5,tweets,575081859391954946
10.1080/15283488.2017.1379907,Psychology_tweet_253,"New article on multiethnic-racial identity by Dr. Jordan Soliz, Gretchen Bergquist &amp; @username SRP student Sierra Cronan
","Tonia also spoke to the lack of interethnic-racial groups and families in her community or in the media to provide models for behavior: ""It's kinda' something I'm almost insecure about so I think that's why it's a challenge for me.""","New article on multiethnic-racial identity by Dr. Jordan Soliz, Gretchen Bergquist &amp; @username SRP student Sierra Cronan
","In Eric's case, a ""mixed"" identity was something distinctly different from other ethnic-racial groups and one that was not explicitly recognized or affirmed. Tonia also spoke to the lack of interethnic-racial groups and families in her community or in the media to provide models for behavior: ""It's kinda' something I'm almost insecure about so I think that's why it's a challenge for me."" In fact, she spoke to moving to communities with more interethnic-racial social groups and individuals with mixed backgrounds as a positive change in her life.","[2.0, 3.0, 1.0, 2.0, 3.0]",Psychology,train,2.2,tweets,924996048594112512
10.1111/jcc4.12063,Psychology_tweet_255,"How do emoticons function in workplace email, new in JCMC   via @username :-)","Jeg har sikkert blingset vedr signatur, så der har du sikkert rett :-)","How do emoticons function in workplace email, new in JCMC   via @username :-)","Thanks for your help -and now I promise that I have contacted you for the last time concerning this case:-) Jeg har sikkert blingset vedr signatur, så der har du sikkert rett :-) I have probably read the signature incorrectly, so there you're probably right :-)","[1.0, 2.0, 3.0, 1.0]",Psychology,train,1.75,tweets,422765140518649856
10.1016/j.evolhumbehav.2014.08.003,Psychology_tweet_256,"New paper from lab of BCS prof Ben Hayden ( Color, macaques, + female gaze of photos of males ","To our knowledge, this is the first demonstration of an extraneous color effect in non-human primates.","New paper from lab of BCS prof Ben Hayden ( Color, macaques, + female gaze of photos of males ","The greater lookingtime by females for the male scrotum on a red background suggests that females saw this stimulus as more interesting compared to other stimuli , and the absence of an effect for looking duration in males suggests they did not find this stimulus more interesting. To our knowledge, this is the first demonstration of an extraneous color effect in non-human primates. Extraneous red increased females' interest in viewing a male scrotum while extraneous blue did not.","[2.0, 2.0, 2.0, 5.0, 1.0]",Psychology,train,2.0,tweets,516428175988248578
10.1016/j.jenvp.2019.04.012,Psychology_tweet_257," A longitudinal experimental shows that teaching people about the science behind GM foods results in more positive attitudes, greater willingness to eat GM products, and seeing GM foods as being less risky. #sciencenews ","Subjects were primarily white (78%); 33% had a bachelor's degree, 27% had some college, 20% had an advanced degree, and 11% had a high school education or less."," A longitudinal experimental shows that teaching people about the science behind GM foods results in more positive attitudes, greater willingness to eat GM products, and seeing GM foods as being less risky. #sciencenews ","Subjects were 362 adults (142 female) with an average age of 33.53 years (SD = 10.88). Subjects were primarily white (78%); 33% had a bachelor's degree, 27% had some college, 20% had an advanced degree, and 11% had a high school education or less. Fiftyfour subjects were excluded for failing at least one attention check or for not completing the main measures, resulting in a final sample of n = 309.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,1127252338807312384
10.1186/s12889-017-4675-z,Psychology_tweet_258,"""‘Working is healthy; it keeps you young"" Why older workers work beyond the retirement age - a qualitative study: ","In the domain of purpose in life, the participants indicated three specific motives for remaining in the work force.","""‘Working is healthy; it keeps you young"" Why older workers work beyond the retirement age - a qualitative study: ","Now I can save more money and I can spend it on travelling.' In the domain of purpose in life, the participants indicated three specific motives for remaining in the work force. You are not standing on the sideline, which is something what happens if you are ageing.","[3.0, 3.0, 4.0, 4.0, 4.0]",Psychology,train,3.6,tweets,903191929936072704
10.1038/s41598-018-30980-y,Psychology_tweet_26,"New study shows that naps benefit and improve memory in early childhood. ☝️
For those blaming themselves during #nap time, you now can get them to #sleep with good conscience! 
#parenting #Children #Health ","As such, emotional memories may benefit from SWS presence in the naps, which accounts for 42% of naps at this age.","New study shows that naps benefit and improve memory in early childhood. ☝️
For those blaming themselves during #nap time, you now can get them to #sleep with good conscience! 
#parenting #Children #Health ","Likewise, negative memories selectively cued during SWS are better remembered than uncued items 8 . As such, emotional memories may benefit from SWS presence in the naps, which accounts for 42% of naps at this age. Naps in early childhood support declarative memory consolidation.","[3.0, 3.0, 3.0]",Psychology,train,3.0,tweets,1032557106388447234
10.1177/0963662516629749,Psychology_tweet_260,1st of the PUS prize-winning papers: The lure of rationality: Why does the deficit model persist in science comm? ,"In an era where science is becoming increasingly contentious politically, curriculum reform that is designed to produce a more educated citizenry represents an area of common ground for virtually all actors in the policy making process.",1st of the PUS prize-winning papers: The lure of rationality: Why does the deficit model persist in science comm? ,"While it would be naïve to suggest that curriculum reform is a simple process, an approach to the lagging levels of public support for science that focuses on education enjoys at least one key advantage; it promises to be a largely bipartisan effort, at least relative to other approaches that might target values or employ persuasive messaging. In an era where science is becoming increasingly contentious politically, curriculum reform that is designed to produce a more educated citizenry represents an area of common ground for virtually all actors in the policy making process. debates over teaching evolution), Republicans and Democrats, the rich and the poor, scientists and lay audiences all understand the need for a scientifically literate and informed citizenry.","[1.0, 4.0, 3.0, 2.0]",Psychology,train,2.5,tweets,728210268925333505
10.1038/s41598-018-27468-0,Psychology_tweet_261,How #physiological and #social determinants affect sharing behaviour in #children ,"In the same study, the children's behaviour was comparable to that of adult chimpanzees, who also shared with their interaction partners as long as both of them received the high-quality reward, while human adults acted prosocially, irrespective of the quality of their own reward 22 .",How #physiological and #social determinants affect sharing behaviour in #children ,"However, since in our study both the donor and the recipient always received the same reward item, it is not clear whether the children's prosocial donations in our study were mainly motivated by a preference for equitable outcomes or not. In the same study, the children's behaviour was comparable to that of adult chimpanzees, who also shared with their interaction partners as long as both of them received the high-quality reward, while human adults acted prosocially, irrespective of the quality of their own reward 22 . We further found that the children's age had no effect on whether they acted prosocially or not, albeit the age range in our sample was rather small (6-9 years).","[1.0, 2.0, 3.0, 2.0]",Psychology,train,2.0,tweets,1013384239377764353
10.1002/hbm.23803,Psychology_tweet_262,rTMS-induced ⬇️'s in local activity associated with ⬆️ in long-range connectivity during episodic memory encoding.  ,"Consistent with this prediction, Figure 8 clearly shows that WMD in a number of ROIs near the stimulated left MFG region were enhanced by 5 Hz rTMS, including the stimulation site (5 Hz: t 13 5 3.45, P < 0.005; 1 Hz: t 13 5 0.32, P 5 n.s.).",rTMS-induced ⬇️'s in local activity associated with ⬆️ in long-range connectivity during episodic memory encoding.  ,"No such relationships were observed in the relationship between univariate activity and WMD at the stimulation site (all r < 0.05), nor did whole-brain distributions show differences between stimulation conditions. Consistent with this prediction, Figure 8 clearly shows that WMD in a number of ROIs near the stimulated left MFG region were enhanced by 5 Hz rTMS, including the stimulation site (5 Hz: t 13 5 3.45, P < 0.005; 1 Hz: t 13 5 0.32, P 5 n.s.). Additionally, 5 Hz rTMS also increased memory- BMD associated with SME across rTMS conditions.","[1.0, 2.0, 1.0]",Psychology,train,1.3333333333333333,tweets,906299924358287362
10.1073/pnas.1509654112,Psychology_tweet_263,"Next time some tech employee justifies gender inequality through differences in male and female brains, please refer him to this.  ",The size of each circle is proportional to the percent of individuals from the same sex/gender category with an identical score on the two measures.,"Next time some tech employee justifies gender inequality through differences in male and female brains, please refer him to this.  ",Another noteworthy observation is that the size of the sex/gender Fig. The size of each circle is proportional to the percent of individuals from the same sex/gender category with an identical score on the two measures. difference in some regions varied considerably between different datasets (Table S1 ).,"[2.0, 4.0, 1.0, 3.0]",Psychology,train,2.5,tweets,991404843582545920
10.1177/0022146514533347,Psychology_tweet_264,New study finds skinny people make overweight people less #happy. #science #psychology ,"In counties with higher levels of obesity, this difference virtually disappears (less than 1.5 percent separates the nonobese and severely obese, and the difference between the nonobese and obese is less than .5 percent).",New study finds skinny people make overweight people less #happy. #science #psychology ,"For men in low-obesity counties, there is little more than a 2 and 7 percentage point respective difference between the obese and nonobese, and severely obese and nonobese, in the likelihood of reporting high life satisfaction. In counties with higher levels of obesity, this difference virtually disappears (less than 1.5 percent separates the nonobese and severely obese, and the difference between the nonobese and obese is less than .5 percent). In other words, there is almost no emotional cost of obesity in terms of life satisfaction for men living in high-obesity counties.","[1.0, 2.0, 3.0, 3.0]",Psychology,train,2.25,tweets,474581490240851969
10.1177/0146167206288599,Psychology_tweet_265,#PersonalityPlasticity After Age 30 ,"Using that model, Costa and McCrae (1992c) projected that the median stability of GZTS true scores after 50 years would be .60, and concluded that ""about three-fifths of the variance in personality traits is stable across the full adult age range"" (p. 182).",#PersonalityPlasticity After Age 30 ,"Retest correlations are typically lower over longer retest intervals-for example, the median retest correlation for GZTS scales after 6 years was .77; after 24 years it was .65 (Costa & McCrae, 1992c )-and researchers have typically assumed an exponential decay of consistency (e.g., . Using that model, Costa and McCrae (1992c) projected that the median stability of GZTS true scores after 50 years would be .60, and concluded that ""about three-fifths of the variance in personality traits is stable across the full adult age range"" (p. 182). pointed out that the exponential decay model predicts that eventually rank-order consistency will decline to zero unless there are developmental constancy factors (such as one's unchanging genetic endowment) that force consistency to a non-zero asymptote.","[1.0, 3.0, 1.0]",Psychology,train,1.6666666666666667,tweets,827091412160221184
10.1073/pnas.1706541114,Psychology_tweet_266,"Personal Success: Use Your Money to Buy Back Your Time - Researchers say it promotes happiness
 ",It is possible that the time-saving and material purchases could differ in various ways.,"Personal Success: Use Your Money to Buy Back Your Time - Researchers say it promotes happiness
 ","All results also remain significant using two-tailed tests. It is possible that the time-saving and material purchases could differ in various ways. We provide evidence that using money to buy time can provide a buffer against this time famine, thereby promoting happiness.","[1.0, 1.0, 3.0, 1.0, 1.0]",Psychology,train,1.4,tweets,986977230285918213
10.1016/j.psyneuen.2018.06.017,Psychology_tweet_267,"Depression-induced inflammation during pregnancy may impact newborns, finds new @username funded research.  New research from @username and colleagues online today in Psychoneuroendocrinology  ","As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mother-infant dyads (51 controls and 36 cases) were assessed.","Depression-induced inflammation during pregnancy may impact newborns, finds new @username funded research.  New research from @username and colleagues online today in Psychoneuroendocrinology  ","Of the total sample, 41 (84%) had a past history of MDD. As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mother-infant dyads (51 controls and 36 cases) were assessed. However, there was no statistically significant difference at any time point between the proportion of cases and controls remaining in the study; furthermore, there were no statistically significant differences in socio-demographic information at baseline between those who did and did not complete the 1 year assessments, either for cases or for controls (data not shown).","[2.0, 4.0, 1.0, 1.0]",Psychology,train,1.0,tweets,1019827275641118720
10.1038/nn.3303,Psychology_tweet_268,Sleep assists with memory processing ,"When recognition based on recollection and on familiarity were summed, no sleep-wake .",Sleep assists with memory processing ,"They found a sleep-dependent benefit for gist words based on recollection memory, but reduced memory based on familiarity. When recognition based on recollection and on familiarity were summed, no sleep-wake . Similarly, probabilistic category learning, studied in the weather prediction task (right), shows significant improvement after a night of sleep, and significantly more than after an equal period awake during daytime, when no significant improvement was seen.","[3.0, 3.0, 2.0]",Psychology,train,2.6666666666666665,tweets,296461949342994432
10.1038/nn.3794,Psychology_tweet_269,"As number of viewings of the same image increases, inhibitory neurons found to fire more and more strongly in th... ","Paradoxical interactions conforming to this pattern do, however, occur in inhibition-stabilized networks 4 44 .","As number of viewings of the same image increases, inhibitory neurons found to fire more and more strongly in th... ","Because putative inhibitory neurons themselves exhibit strong response truncation, it seems implausible that they could impose response truncation on excitatory neurons. Paradoxical interactions conforming to this pattern do, however, occur in inhibition-stabilized networks 4 44 . The late phase of the visual response might depend in part on recurrent excitatory connections among these neurons.","[1.0, 4.0, 3.0, 3.0]",Psychology,train,2.75,tweets,505213296669388800
10.1001/jamapsychiatry.2017.3998,Psychology_tweet_27,Transdermal #estradiol w #progesterone effective in averting #depressive symptoms in #perimenopausal and early #postmenopausal women  ,CONCLUSIONS Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women.,Transdermal #estradiol w #progesterone effective in averting #depressive symptoms in #perimenopausal and early #postmenopausal women  ,"Baseline estradiol levels, baseline vasomotor symptoms, history of depression, and history of abuse did not moderate treatment effects. CONCLUSIONS Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01308814","[5.0, 3.0, 4.0, 4.0]",Psychology,train,4.0,tweets,951136572157685760
10.1073/pnas.1414784111,Psychology_tweet_270,More evidence that changing hormonal contraception can affect female relationship and sexual satisfaction ,Discontinuing HCs may interact with husbands' facial attractiveness because it recalibrates women's relationship satisfaction to be more sensitive to such cues.,More evidence that changing hormonal contraception can affect female relationship and sexual satisfaction ,"Given that HCs are thought to disrupt this circuitry, it makes sense that they would weaken the extent to which relationship satisfaction is sensitive to any cues of partner genetic fitness, including facial attractiveness. Discontinuing HCs may interact with husbands' facial attractiveness because it recalibrates women's relationship satisfaction to be more sensitive to such cues. Sexual satisfaction as measured here , in contrast, captures the extent to which partners derive physical pleasure from their sexual activities.","[3.0, 5.0, 3.0, 1.0]",Psychology,train,2.0,tweets,534503747117150209
10.1080/09687599.2018.1497950,Psychology_tweet_273,Thank you @username for excellent networking sharing @username papers ,"As already described, 11 articles fulfilled the reviews inclusion criteria.",Thank you @username for excellent networking sharing @username papers ,"Furthermore, greater levels of generalisability could be provided by drawing on a wider range of participants and settings. As already described, 11 articles fulfilled the reviews inclusion criteria. The vast majority of the studies employed a range of qualitative techniques (e.g.","[1.0, 1.0, 1.0, 2.0, 1.0]",Psychology,train,1.2,tweets,1063006368809009153
10.1509/jmr.13.0499,Psychology_tweet_274,Lego kits kill #creativity! Another example of research not considering variability of creative style. ,The marketplace essentially offers more products that engage us in well-defined-problem solving.,Lego kits kill #creativity! Another example of research not considering variability of creative style. ,"Furthermore, the results show that the effect of this mindset on consumers' choice is rather robust-it occurs even when we control for the effect of a chronic individual-difference factor (self-perceived creativity) and endures after a delay (i.e., as demonstrated by the order manipulation). The marketplace essentially offers more products that engage us in well-defined-problem solving. By considering the effects of a well-defined-problemsolving mindset on both goal striving and goal setting, our studies suggest that the consequences of such a mindset could be significant.","[2.0, 1.0, 3.0, 1.0]",Psychology,train,1.75,tweets,611361899343663104
10.1177/070674370705200508,Psychology_tweet_275,Here’s the thing: The text described in the Montreal Cognitive Assessment does not test for any of the issues Trump exhibits. It’s designed to spot signs of dementia and that’s pretty much it. It means nothing in this case.  ,La sensibilité et la spécificité des deux mesures ont été évaluées pour la détection du TCL et de la démence.,Here’s the thing: The text described in the Montreal Cognitive Assessment does not test for any of the issues Trump exhibits. It’s designed to spot signs of dementia and that’s pretty much it. It means nothing in this case.  ,"Les diagnostics cliniques de démence et de TCL ont été posés d'après les critères du CIM-10 et de Petersen. La sensibilité et la spécificité des deux mesures ont été évaluées pour la détection du TCL et de la démence. Résultats : Avec un score d'inclusion de 26, le MMSE avait une sensibilité de 17 % pour détecter les sujets souffrant de TCL, alors que la MoCA en détectait 83 %.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,953448360806989824
10.1073/pnas.1221880110,Psychology_tweet_276,ASD = shorter gray matter connections corr w repetitive behavior. BUT only 34 males &amp; only % ASD  have repetitive beh ,"S4) , if the MSD of a point is high, then that point is relatively more isolated (i.e., in a low-density environment) compared with a point with a low MSD (i.e., in a high-density environment).",ASD = shorter gray matter connections corr w repetitive behavior. BUT only 34 males &amp; only % ASD  have repetitive beh ,"Theoretically (Fig. S4) , if the MSD of a point is high, then that point is relatively more isolated (i.e., in a low-density environment) compared with a point with a low MSD (i.e., in a high-density environment). Thus, comparing MSD distributions across groups may reveal regions that have relatively greater or lesser density of underlying ""surface units.""","[2.0, 2.0, 2.0, 3.0, 3.0]",Psychology,train,2.4,tweets,359792378883751936
10.1080/00224499.2016.1233315,Psychology_tweet_277,"Contrary to popular belief, under the right conditions sexual quality of life INCREASES w age, due to #SexualWisdom. ","Only the fixed effects varied between the models, with each research question requiring additional effects to be added to the model.","Contrary to popular belief, under the right conditions sexual quality of life INCREASES w age, due to #SexualWisdom. ","It was extended to include SQoL in MIDUS and is based on respondents' own criteria for evaluating the quality of the sexual aspects of their life . Only the fixed effects varied between the models, with each research question requiring additional effects to be added to the model. These results are available in the online supplement.","[1.0, 3.0, 2.0, 1.0]",Psychology,train,1.75,tweets,798647099910922240
10.1098/rspb.2018.1366,Psychology_tweet_279,"In social spiders, resting interactions shape individuals' personality, so that effective collective phenotypes are achieved. Proud publication of first @username postdoc paper! My research into collective dynamics ongoing @username @username 🕷️ ","Finally, because we model the change in network tie formation and boldness change over 19 observations, there are 18 periodspecific rate constants for each of these (inter-)dependent variables.","In social spiders, resting interactions shape individuals' personality, so that effective collective phenotypes are achieved. Proud publication of first @username postdoc paper! My research into collective dynamics ongoing @username @username 🕷️ ","Thus, while it is a necessary effect, it is not biologically informative. Finally, because we model the change in network tie formation and boldness change over 19 observations, there are 18 periodspecific rate constants for each of these (inter-)dependent variables. Similar to network density, these constants are not of focal interest [45] .","[2.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.2,tweets,1037287686275588096
10.1111/ajps.12118,Psychology_tweet_281,That paper new from @username here: ,"Under such a theory, it is possible that we would see a general liberal trend among those having daughters across many cases having a gendered component, specifically cases involving discrimination against women.",That paper new from @username here: ,"Under this theory, parents would want to protect their daughters from possible gender-based discrimination, resulting in increased progressive views on employment or pregnancy discrimination law. Under such a theory, it is possible that we would see a general liberal trend among those having daughters across many cases having a gendered component, specifically cases involving discrimination against women. (However, we might also see a conservative trend among reproductive rights or abortion cases.)","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,464872444684423168
10.1038/s41598-017-18902-w,Psychology_tweet_282,"Link to journal article:
",Our results have thus unraveled a significant correlation between movement and other aspects of Autism development.,"Link to journal article:
","This result provides added evidence about the independent reliability of using the R-parameter classification. Our results have thus unraveled a significant correlation between movement and other aspects of Autism development. the noise level present in the motor output, may provide an underlying mechanism contributing to the variable motion disturbances present in the spectrum, as well as in other autistic symptons.","[1.0, 1.0, 1.0, 2.0, 1.0]",Psychology,train,1.2,tweets,954619746703560704
10.3402/ejpt.v5.22250,Psychology_tweet_284,Measuring fragmentation in dissociative identity disorder ,"For highbetrayal trauma after age 18, the mean score was 9.20 (SD 04.57).",Measuring fragmentation in dissociative identity disorder ,"Participants had a mean score of 19.10 (SD010.84) for all trauma after age 18. For highbetrayal trauma after age 18, the mean score was 9.20 (SD 04.57). These levels of reported trauma are much higher than those reported by young adult populations (see for comparison results).","[1.0, 1.0, 2.0, 1.0]",Psychology,train,1.25,tweets,704285300986650624
10.1177/0956797615575277,Psychology_tweet_286, inauthenticity linked immorality - Holden Caulfield would approve.,"The remaining three word segments (F_ O _, B_ _ K, and PA_ _ R) could be completed with neutral words only.", inauthenticity linked immorality - Holden Caulfield would approve.,"Three of the word segments (W_ _H, SH_ _ER, and S_ _P) could be completed as cleansing-related words (wash, shower, and soap) or as unrelated, neutral words (e.g., wish, shaker, and step). The remaining three word segments (F_ O _, B_ _ K, and PA_ _ R) could be completed with neutral words only. We averaged responses to the five cleansing products to create one aggregate measure (α = .86).","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,598497300877602817
10.1080/02640410500189033,Psychology_tweet_287,"@username However, some studies say that the Kisii tribe is more succesful than Kikuyus. ","Although mirrored in Ethiopia , these findings are in stark contrast to the sedentary lifestyles of young Scottish children and the increasing prevalence of childhood obesity in the USA and UK .","@username However, some studies say that the Kisii tribe is more succesful than Kikuyus. ","In this study, a higher proportion of international (51%, P 5 0.002) and national athletes (42%, P 5 0.01) travelled farther than 5 km to school each day than controls (25%) ( Figure 5 ). Although mirrored in Ethiopia , these findings are in stark contrast to the sedentary lifestyles of young Scottish children and the increasing prevalence of childhood obesity in the USA and UK . Athletes also differed from controls in their method of travel to school, with a higher proportion of athletes running to school each day [controls 22%; national athletes 73% (P 5 0.001); international athletes 82% (P 5 0.001)].","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,352062845292261376
10.1038/s41598-018-30798-8,Psychology_tweet_288,Woo! a great collaboration between @username  and @username its been an absolute pleasure ,Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age.,Woo! a great collaboration between @username  and @username its been an absolute pleasure ,"adults and older children were more easily influenced by vision). Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age. The McGurk effect exemplifies this, as hearing a voice say ""Ba"" and seeing a face say ""Ga"" often results in perception of an alternative syllable such as ""Da"" or ""Tha"" 1 .","[1.0, 4.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,1030389403913474048
10.1073/pnas.1816076116,Psychology_tweet_289,Interesting study on diversity training. ,"On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training.",Interesting study on diversity training. ,"Among groups whose average untreated attitudes-whereas still supportive of women-were relatively less supportive of women than other groups, our diversity training successfully produced attitude change but not behavior change. On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training. This paper extends our knowledge about the pathways to attitude and behavior change in the context of bias reduction.","[2.0, 5.0, 4.0, 3.0, 4.0]",Psychology,train,3.6,tweets,1114917947011682304
10.1001/jamapsychiatry.2018.2462,Psychology_tweet_29,"Really fascinating: A 20-yr cohort study of nearly 200,000 women shows that depression is associated with a 2-fold increase in the risk of developing lupus. All the more reasons to pay attention to #MentalHealth!  ","Compared with women with no depression, women with a history of depression had a subsequent increased risk of SLE (HR, 2.67; 95% CI, 1.91-3.75; P < .001).","Really fascinating: A 20-yr cohort study of nearly 200,000 women shows that depression is associated with a 2-fold increase in the risk of developing lupus. All the more reasons to pay attention to #MentalHealth!  ","During 20 years of follow-up, 145 cases of SLE occurred. Compared with women with no depression, women with a history of depression had a subsequent increased risk of SLE (HR, 2.67; 95% CI, 1.91-3.75; P < .001). Adjustment for body mass index, cigarette smoking, and oral contraception and postmenopausal hormone use slightly attenuated associations (adjusted HR, 2.45; 95% CI, 1.74-3.45; P < .001).","[5.0, 1.0, 4.0, 4.0]",Psychology,train,4.0,tweets,1039897575581790209
10.1007/s40279-018-0916-2,Psychology_tweet_290,"Are cool-downs a waste of time?

We debate the relative merits of both warm-ups and cool-downs during our 3rd year #Sports #Physiology unit on @username
 
An interesting paper to add to the reading list!

","An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter.","Are cool-downs a waste of time?

We debate the relative merits of both warm-ups and cool-downs during our 3rd year #Sports #Physiology unit on @username
 
An interesting paper to add to the reading list!

","Strategies that enhance the resynthesis of glycogen may therefore attenuate the decrease in performance and even enhance performance. An active cool-down may theoretically enhance glycogen resynthesis, because an increased blood flow and elevated muscle temperature could increase glucose delivery to muscle tissue , while muscle contraction may increase the expression of the GLUT-4 glucose transporter. Therefore, these findings suggest that an active cool-down may interfere with muscle glycogen resynthesis, particularly within type I muscle fibers , because these fibers are preferentially recruited during a low-to moderate-intensity active cool-down.","[2.0, 3.0, 3.0, 2.0, 2.0]",Psychology,train,2.4,tweets,1009431597819494400
10.1073/pnas.1218772110,Psychology_tweet_291,Personality profile based on your Facebook likes ,"Positive cases are those classified by the model to belong to a target class (e.g., ""male"" or ""Democrat"").",Personality profile based on your Facebook likes ,"Predictions. Positive cases are those classified by the model to belong to a target class (e.g., ""male"" or ""Democrat""). Thus, true positive cases are the cases that were correctly classified by the model as belonging to a target class, whereas false-positive cases were classified incorrectly as belonging to a target class.","[2.0, 1.0, 1.0, 2.0, 1.0]",Psychology,train,1.4,tweets,311462963389296640
10.1016/j.amjmed.2014.02.007,Psychology_tweet_293,"@username Running somewhere fast...
""in older Americans, muscle mass relative to body height was inversely associated with all-cause mortality"" ",The median age at the end of follow-up (or censoring) for those not known to have died was 80.6 years; 10 individuals were aged 100 years or more at the end of follow-up.,"@username Running somewhere fast...
""in older Americans, muscle mass relative to body height was inversely associated with all-cause mortality"" ",The median age at death was 82.7 years; 7 individuals were aged 100 years or more at the time of death. The median age at the end of follow-up (or censoring) for those not known to have died was 80.6 years; 10 individuals were aged 100 years or more at the end of follow-up. Unadjusted all-cause mortality risk was significantly higher in the lowest muscle mass index quartile compared with the highest muscle mass index quartile (58% compared with 41%; relative reduction of 30%) ( Table 2 ).,"[3.0, 2.0, 1.0, 1.0, 1.0]",Psychology,train,1.6,tweets,1128372480597319680
10.1177/0146167218781000,Psychology_tweet_295,Nature is not woke. ,Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings.,Nature is not woke. ,"The interaction of pHS and willingness to invest was also non-significant meaning that the relationship between perceived willingness to invest and attractiveness was not affected by high versus low pHS. Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings. Specifically, women's perceived level of male HS did not predict the attractiveness of the BS romantic partner, and neither did it moderate the relationship between perceived willingness to invest and attractiveness.","[1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,1068144043476086784
10.1038/s41562-018-0483-4,Psychology_tweet_296,"Humans are very, very complicated:
","While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype.","Humans are very, very complicated:
","The information itself provides a distinct psychological framework through which the individual interprets their current experience and prepares for future experiences and, as a result, this new mindset influences attention, motivation and, most interestingly, physiology in a manner that confirms their expectations 52 . While perceived genetic risk mattered in both experiments, the effects were sometimes driven by negative changes for those who were told that they were at high risk, and sometimes driven by benefits for those who were told that they had the protective genotype. Whether perceived risk elicits a negative effect or perceived protection elicits a positive effect is likely to differ depending on the gene of interest and the experimental paradigm.","[1.0, 4.0, 3.0, 1.0]",Psychology,train,2.0,tweets,1074756603478462464
10.1080/19325037.2017.1343161,Psychology_tweet_297,"Been noticing this same response with some people, yet they insist on still using them #mlrpt #fitbit ","Cronbach's alpha levels for all subscales at pre-and posttest exceeded .70, meeting acceptable criteria (Table 1) .","Been noticing this same response with some people, yet they insist on still using them #mlrpt #fitbit ","."" Cronbach's alpha levels for all subscales at pre-and posttest exceeded .70, meeting acceptable criteria (Table 1) . No strong disagreements between the authors occurred during this process.","[1.0, 1.0, 1.0, 1.0, 1.0]",Psychology,train,1.0,tweets,912186287507075073
10.1073/pnas.1706541114,Psychology_tweet_298,"like purchasing a #Roomba? Buying #time promotes #happiness,  via @username",It is possible that the time-saving and material purchases could differ in various ways.,"like purchasing a #Roomba? Buying #time promotes #happiness,  via @username","All results also remain significant using two-tailed tests. It is possible that the time-saving and material purchases could differ in various ways. We provide evidence that using money to buy time can provide a buffer against this time famine, thereby promoting happiness.","[1.0, 2.0, 1.0, 3.0, 2.0]",Psychology,train,1.8,tweets,890307017281294336
10.1001/jamapsychiatry.2018.0747,Psychology_tweet_30,RT @username: Lower #heartrate variability at baseline is a risk factor for #depression &amp; highlights an important role of the autonomic nervous system. Learn more  ,These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease.,RT @username: Lower #heartrate variability at baseline is a risk factor for #depression &amp; highlights an important role of the autonomic nervous system. Learn more  ,The opposite causal pathway from depression to lower HRV is mostly driven by antidepressant use. These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease. Reduced HRV is a marker of decreased ANS flexibility and may reflect an increase in the sympathetic nervous system and/or a decrease in the parasympathetic nervous system modulation.,"[4.0, 3.0, 4.0, 3.0]",Psychology,train,3.5,tweets,999005816593305601
10.1111/sode.12203,Psychology_tweet_31,"Pet dogs help kids feel less stressed! 
New research from our lab. Full report at  ","Results supported the notion that pet dogs buffer children's perceived stress response; however, the results with children's cortisol response were more complex.","Pet dogs help kids feel less stressed! 
New research from our lab. Full report at  ","Dyadic interaction factors during the TSST-C were unrelated to perceived stress or cortisol assessed for baseline or recovery, indicating that dyadic interaction was linked only with the rise in cortisol during the TSST-C. Results supported the notion that pet dogs buffer children's perceived stress response; however, the results with children's cortisol response were more complex. The divergent finding for perceived stress and cortisol stress responses is not entirely unexpected, as perceived stress and neuroendocrine responses to stress are believed to be mediated by different cognitive and neurobiological pathways .","[5.0, 4.0, 4.0, 3.0, 4.0]",Psychology,train,4.0,tweets,860926168228409344
10.1073/pnas.1421285111,Psychology_tweet_32,Can the ALS drug riluzole help reverse age-related memory loss? #ALS #memory,"Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats.",Can the ALS drug riluzole help reverse age-related memory loss? #ALS #memory,"Although neuron death is minimal in the absence of AD, age-related cognitive decline does occur in animals as well as humans, and it decreases quality of life for elderly people. Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats. Treated aged rats were protected against age-related cognitive decline displayed in nontreated aged animals.","[5.0, 3.0, 5.0, 3.0]",Psychology,train,4.0,tweets,547904717448560640
10.1038/s41598-017-03627-7,Psychology_tweet_33,"Skin to skin touch is important for pain reduction. Effects of touch on  cardio-respiratory inter-partner coupling may contribute to the  analgesic effects of touch via the autonomic nervous system. Experiment.  Heterosexual couples. Men as observer.
","Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling.","Skin to skin touch is important for pain reduction. Effects of touch on  cardio-respiratory inter-partner coupling may contribute to the  analgesic effects of touch via the autonomic nervous system. Experiment.  Heterosexual couples. Men as observer.
","Our findings confirm that interpersonal touch as compared to no-touch is associated with increased respiration coupling, during both pain and no-pain conditions. Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling. The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain.","[3.0, 5.0, 3.0, 2.0]",Psychology,train,3.25,tweets,987989220265521152
10.1093/jcr/ucw012,Psychology_tweet_34,"A new report reveals the impact of behaviorally targeted ads on consumers (PDF) (h/t @username)
","We therefore predict that when the label implied by a behaviorally targeted advertisement is plausibly connected to the consumer's prior behavior (i.e., the targeting is at least moderately accurate), consumers perceive that the marketer has labeled them correctly and respond accordingly, altering their self-perceptions and hence behavior to be consistent with the identity implied by the ad.","A new report reveals the impact of behaviorally targeted ads on consumers (PDF) (h/t @username)
","However, if there is a plausible connection between the label and past behavior, the label is accepted and consumers adjust self-perceptions and behavior in line with that label. We therefore predict that when the label implied by a behaviorally targeted advertisement is plausibly connected to the consumer's prior behavior (i.e., the targeting is at least moderately accurate), consumers perceive that the marketer has labeled them correctly and respond accordingly, altering their self-perceptions and hence behavior to be consistent with the identity implied by the ad. In contrast, when the label is unconnected with their prior behavior (i.e., targeting is inaccurate), consumers will not accept the implied label and will not adjust their self-perceptions and behavior.","[3.0, 4.0, 5.0, 3.0, 4.0]",Psychology,train,3.8,tweets,718816497720659969
10.1016/j.jalz.2018.06.2856,Psychology_tweet_35,"Eye Conditions Linked to Higher Alzheimer's Risk.
","Even though our primary outcome was clinical AD diagnosis, we found similar relationships with all-cause dementia with all three ophthalmic conditions (Supplementary Table 1 ).","Eye Conditions Linked to Higher Alzheimer's Risk.
","It is common to evaluate risk factors in the larger group of people with clinical diagnoses and attempt to confirm those risk factors with more specific neuropathology data in the smaller subset of individuals who have died and come to autopsy. Even though our primary outcome was clinical AD diagnosis, we found similar relationships with all-cause dementia with all three ophthalmic conditions (Supplementary Table 1 ). The 5-year cutoff to delineate recent versus established condition could be viewed as a limitation.","[3.0, 4.0, 2.0, 1.0]",Psychology,train,2.5,tweets,1029608724954939392
10.1016/j.jpeds.2017.10.028,Psychology_tweet_37,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,"Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59).",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,"Results In all, 19% of participants (n = 134) reported physical dating violence perpetration and 68% reported experiencing corporal punishment as children (n = 498). Analysis showed a significant positive association between corporal punishment and physical perpetration of dating violence (OR 1.30, 95% CI 1.07-1.59). Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62).","[4.0, 4.0, 5.0, 4.0, 5.0]",Psychology,train,4.4,tweets,940635000571035649
10.1016/j.jneb.2014.02.008,Psychology_tweet_39,Adolescent consumption of sports and energy drinks  ,"Nonhierarchical models with sports drink consumption as the independent variable explained 4% to 19% of variance in health behaviors, and the nonhierarchical models with energy drink consumption as the independent variable explained 4% to 18% of variance in health behaviors.",Adolescent consumption of sports and energy drinks  ,"The overall F value for each model examined was statistically significant at P < .05. Nonhierarchical models with sports drink consumption as the independent variable explained 4% to 19% of variance in health behaviors, and the nonhierarchical models with energy drink consumption as the independent variable explained 4% to 18% of variance in health behaviors. Overall, sports and energy drinks were consumed regularly (at least 1/wk) by 37.9% and 14.7% of the adolescent sample, respectively.","[4.0, 1.0, 3.0, 3.0, 3.0]",Psychology,train,2.8,tweets,466097328991240193
10.1016/j.jalz.2018.06.2856,Psychology_tweet_4,"Eye diseases have been linked to the development of Alzheimer's disease in a new study. Glaucoma, age-related macular degeneration, and diabetic retinopathy were associated with increased Alzheimer's... ","In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not.","Eye diseases have been linked to the development of Alzheimer's disease in a new study. Glaucoma, age-related macular degeneration, and diabetic retinopathy were associated with increased Alzheimer's... ","Finally, our study only evaluated the temporal sequence that starts with ophthalmic conditions followed by AD and not vice-versa thus we are unable to assess whether increased risk for ophthalmic conditions may exist in individuals with AD. In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not. Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat.","[4.0, 1.0, 2.0, 4.0]",Psychology,train,4.0,tweets,1033350420129886208
10.1111/adb.12082,Psychology_tweet_40,High rates of smoking in mentally ill attributed to #addiction vulnerability  #psychology,"Developmental cortical-temporal limbic dysfunction in mental illness may thus amplify nicotine's reinforcing effects and addiction risk and severity, even while producing cognitive deficits that are not specifically or substantially reversible with nicotine.",High rates of smoking in mentally ill attributed to #addiction vulnerability  #psychology,"These findings represent the first prospective evidence demonstrating a causal link between disease processes in schizophrenia and nicotine addiction. Developmental cortical-temporal limbic dysfunction in mental illness may thus amplify nicotine's reinforcing effects and addiction risk and severity, even while producing cognitive deficits that are not specifically or substantially reversible with nicotine. Although this research has imparted neuroscientific credence to a medicinal value for nicotine use in schizophrenia, recently emerging data indicate that acute nicotine dosing has no cognitive therapeutic benefits for schizophrenic compared to nonschizophrenia smokers .","[4.0, 2.0, 4.0, 2.0, 4.0]",Psychology,train,3.2,tweets,385168451217547264
10.1177/0956797614551370,Psychology_tweet_41,The Long Reach of One's Spouse - Spouses' Personality Influences Occupational Success [a]  HT @username,"These results suggest that people with conscientious spouses tend to emulate certain characteristics of their spouses (via their joint lifestyle), and that these characteristics, in turn, are positively associated with satisfaction at work and likelihood of being promoted.",The Long Reach of One's Spouse - Spouses' Personality Influences Occupational Success [a]  HT @username,"Emulation explained the effect of partner conscientiousness on both job satisfaction, indirect effect = 0.004, 95% CI = [0.002, 0.006], and on job promotion, indirect effect = 0.004, 95% CI = [0.000, 0.008] (Table 4) . These results suggest that people with conscientious spouses tend to emulate certain characteristics of their spouses (via their joint lifestyle), and that these characteristics, in turn, are positively associated with satisfaction at work and likelihood of being promoted. Finally, we examined spillover of relationship satisfaction, and again we found that partner conscientiousness had a positive indirect effect on job satisfaction, point estimate = 0.014, 95% CI = [0.011, 0.017] (Table 4) .","[4.0, 3.0, 3.0, 3.0, 2.0]",Psychology,train,3.0,tweets,525313475477000192
10.1111/cdep.12038,Psychology_tweet_42,Spanking &amp; Child Development - We Know Enough Now to Stop Hitting Our Children  HT @username @username,"Rather, spanking predicted increases in children's aggression over and above initial levels.",Spanking &amp; Child Development - We Know Enough Now to Stop Hitting Our Children  HT @username @username,"In these studies, although children's aggressive behavior often elicited more spanking over time, this effect did not entirely explain the association between spanking and children's aggression. Rather, spanking predicted increases in children's aggression over and above initial levels. Spanking consistently predicted increases in children's aggression over time, regardless of how aggressive children were when the spanking occurred.","[4.0, 3.0, 3.0]",Psychology,train,3.333333333333333,tweets,510607452199747584
10.1177/1533317514549411,Psychology_tweet_43,"In late life, drinkers have larger hippocampi and better episodic memory than teetotallers  ","This may be due to adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to adverse health outcomes and become abstainers during old age.","In late life, drinkers have larger hippocampi and better episodic memory than teetotallers  ","There were no significant differences in cognitive functioning and regional brain volumes during late life according to midlife alcohol consumption status. This may be due to adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to adverse health outcomes and become abstainers during old age. There also may be an accumulative effect of alcohol consumption on cognitive functioning and regional brain volumes, meaning a person needs to consume alcohol, but not abuse alcohol, for several years or even decades before differences in cognitive functioning and regional brain volumes are observed.","[3.0, 3.0, 4.0, 3.0, 3.0]",Psychology,train,3.2,tweets,525545985041522688
10.1073/pnas.1411228111,Psychology_tweet_44,Marijuana use &amp; decreased brain dopamine reactivity. (Full reference - free access) Via @username ,"The attenuated responses to MP, including reduced decreases in striatal DVs, are consistent with decreased brain reactivity to the DA stimulation in marijuana abusers that might contribute to their negative emotionality (increased stress reactivity and irritability) and addictive behaviors.",Marijuana use &amp; decreased brain dopamine reactivity. (Full reference - free access) Via @username ,"In marijuana abusers, DA responses in ventral striatum were also inversely correlated with addiction severity and craving. The attenuated responses to MP, including reduced decreases in striatal DVs, are consistent with decreased brain reactivity to the DA stimulation in marijuana abusers that might contribute to their negative emotionality (increased stress reactivity and irritability) and addictive behaviors. ).","[2.0, 3.0, 3.0, 5.0]",Psychology,train,3.25,tweets,488872218688909312
10.1002/da.22208,Psychology_tweet_46,Exercise improves sexual function in women taking antidepressants. ,"These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap, and does not add to burden of care.",Exercise improves sexual function in women taking antidepressants. ,"Future trials will be needed to examine effectiveness in a clinical setting (as opposed to a carefully controlled laboratory-based trial). The results of the present study suggest that exercise improves sexual function in women experiencing sexual arousal side effects of antidepressants, with modest evidence of a specific benefit in exercising immediately before sexual activity. These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap, and does not add to burden of care.","[4.0, 5.0, 3.0, 4.0]",Psychology,train,4.0,tweets,443747100216819712
10.1136/bmjsem-2017-000261,Psychology_tweet_47,"""The anticipatory cortisol response before sport competition reflects moderate cortisol reactivity that prepares... ",This shared responsibility to the outcome and opportunities for social interaction reduces cognitive and somatic anxiety responses before sport competition in team sport athletes in comparison to individual athletes.,"""The anticipatory cortisol response before sport competition reflects moderate cortisol reactivity that prepares... ","This cooperation offers opportunities for social interactions between athletes in preparation to and during competition. This shared responsibility to the outcome and opportunities for social interaction reduces cognitive and somatic anxiety responses before sport competition in team sport athletes in comparison to individual athletes. 7 43 In addition, providing verbal social support during psychosocial stress tasks reduces the cortisol response in comparison to not receiving this support.","[1.0, 4.0, 1.0, 4.0, 1.0]",Psychology,train,1.0,tweets,912285926709170176
10.1093/chemse/bjt066,Psychology_tweet_48,"Now You Like Me, Now You Don’t: Labels Impact Odor Perception  #psychology #neuro #uMontreal @username #McGill","Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label.","Now You Like Me, Now You Don’t: Labels Impact Odor Perception  #psychology #neuro #uMontreal @username #McGill","In summary, odor labels affect pleasantness ratings and edibility perception. Although labels appear to also influence intensity ratings and reaction times, this seems to be a more complex relationship that could be modulated by additional factors such as odor valence, label fit, and possibly the edibility attributed to an odor or a label. Odors with different valences impact our mood and wellbeing in different ways.","[3.0, 4.0, 3.0]",Psychology,train,3.333333333333333,tweets,412973466195734529
10.1038/s41598-018-27126-5,Psychology_tweet_49,Study finds that a low-cost weekly music playschool for 5–6-year-old children significantly improved their phoneme-processing &amp; vocabulary skills (no differences in their non-verbal reasoning &amp; inhibition scores) ,Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education.,Study finds that a low-cost weekly music playschool for 5–6-year-old children significantly improved their phoneme-processing &amp; vocabulary skills (no differences in their non-verbal reasoning &amp; inhibition scores) ,"Our data suggest that even playful group music activities -if attended to for several years -have a positive effect on pre-schoolers' linguistic skills. Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education. Musicians outperform non-musicians in syllable discrimination 1 and in detecting speech in noise 2,3 .","[4.0, 2.0, 2.0, 4.0]",Psychology,train,3.0,tweets,1005457236251078656
10.1001/jamapsychiatry.2018.3514,Psychology_tweet_5,"My first, first author paper for my PhD 💃🎉🎊

Looking at the association between psychotic experiences (PE) &amp; suicide. PE are important risk markers for future suicidal thoughts and behaviour. In future, let's ask about them! 

 ","We found that co-occurring psychopathology is only a partial mediator of the association between PEs and suicidal behavior; that is, PEs are a marker of risk for later suicidal behavior in excess of the risk associated with co-occurring mental disorders.","My first, first author paper for my PhD 💃🎉🎊

Looking at the association between psychotic experiences (PE) &amp; suicide. PE are important risk markers for future suicidal thoughts and behaviour. In future, let's ask about them! 

 ","For one, PEs are associated with increased odds of suicidal behavior even in individuals without a mental disorder. We found that co-occurring psychopathology is only a partial mediator of the association between PEs and suicidal behavior; that is, PEs are a marker of risk for later suicidal behavior in excess of the risk associated with co-occurring mental disorders. (Figure 2 includes examples of mediating variables in the association between PEs and suicidal ideation and behavior.)","[4.0, 5.0, 5.0, 4.0, 5.0]",Psychology,train,4.6,tweets,1067819083545096192
10.1073/pnas.1321664111,Psychology_tweet_50,Do we feel emotions in our bodies? ,"We propose that consciously felt emotions are associated with culturally universal, topographically distinct bodily sensations that may support the categorical experience of different emotions.",Do we feel emotions in our bodies? ,"Statistical classifiers discriminated emotion-specific activation maps accurately, confirming independence of bodily topographies across emotions. We propose that consciously felt emotions are associated with culturally universal, topographically distinct bodily sensations that may support the categorical experience of different emotions. One-out linear discriminant analysis (LDA) classified each of the basic emotions and the neutral state against all of the other emotions with a mean accuracy of 72% (chance level 50%), whereas complete classification (discriminating all emotions from each other) was accomplished with a mean accuracy of 38% (chance level 14%) ( Fig.","[5.0, 4.0, 2.0, 3.0]",Psychology,train,3.5,tweets,417928519671238656
10.1093/geronb/gbx110,Psychology_tweet_51,"#Volunteering is not just good for society, it's also good for your #brain and #cognitive function in #older age. ","While the repeated measurement of volunteer involvement is a significant benefit of these data, little is known about the nature of the volunteer work-information that would provide more rigorous tests of theory and likely lead to increased knowledge about which specific aspects of volunteer work are beneficial (or not) for older adults.","#Volunteering is not just good for society, it's also good for your #brain and #cognitive function in #older age. ","It is also probable that those who volunteer self-select into the volunteer role, which might maximize the benefits of volunteering . While the repeated measurement of volunteer involvement is a significant benefit of these data, little is known about the nature of the volunteer work-information that would provide more rigorous tests of theory and likely lead to increased knowledge about which specific aspects of volunteer work are beneficial (or not) for older adults. The wave spacing (every 2 years) of the HRS also does not allow assessment of the waxing and waning in volunteer work that might occur in later adulthood ).","[4.0, 3.0, 2.0, 4.0]",Psychology,train,3.25,tweets,920380385464164352
10.1177/0141076814565942,Psychology_tweet_52,@username @username This just published study says risk of autism may double with infant circumcision ,"More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism.",@username @username This just published study says risk of autism may double with infant circumcision ,"Ritual circumcision among Danish boys is linked to an overall 46-62% increase in ASD risk in the first 10 years of life, with the upper risk estimate obtained after restriction to the period with the most complete data. More strikingly, risk was 80-83% increased in the first 0-4 years of life, an increase that was restricted to infantile autism. To our knowledge, there is no prior evidence to suggest a link between circumcision and hyperactivity disorder, so our finding of an increased risk of this common neurobehavioral disorder among circumcised boys in non-Muslim families was unexpected and needs cautious interpretation.","[3.0, 4.0, 3.0, 3.0, 3.0]",Psychology,train,3.2,tweets,553415532154990593
10.1016/j.jpeds.2017.10.028,Psychology_tweet_53," Spanking your child may have unintended consequences as he or she forges adult romantic relationships years later, a new study suggests. The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researche…","The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence."," Spanking your child may have unintended consequences as he or she forges adult romantic relationships years later, a new study suggests. The study found that spanked kids tended to have higher odds of being violent toward their dating partners, researche…","Finally, even though we controlled important variables (eg, alcohol use, physical child abuse), other factors (eg, interparental violence) could influence findings. The strengths of the present study include a large ethnically diverse sample, and the use of methodologically sound measures of dating violence. Furthermore, variables known to relate to dating violence were controlled for, which highlights the importance of the unique impact of corporal punishment on perpetration of dating violence and addresses longstanding criticisms regarding a potentially confounding link between corporal punishment and poor outcomes.","[1.0, 1.0, 3.0, 1.0]",Psychology,train,1.5,tweets,938074851071406081
10.1038/s41598-017-03627-7,Psychology_tweet_54,Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect.",Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"Physiologically, interpersonal touch increases the coupling of electrodermal activity and pulse rate variability 35 and modulates blood pressure reactivity to stress 36 as well as reactivity to distress 37 . As was reported in the initial report of this data (Goldstein et al., 2016) , the pain ratings in the partner-touch condition were lower than in the partner-no touch condition (M diff = −0.36, p = 0.029) and the pain-alone condition (M diff = −0.66, p < 0.001), confirming that touch had an analgesic effect. In addition, during the pain-alone condition, the women's pain ratings were marginally higher than in the partner-no touch condition (M diff = 0.29, p = 0.093).","[3.0, 3.0, 4.0]",Psychology,train,3.333333333333333,tweets,877405828629876736
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_55,"Neural mechanisms linking depressive symptoms with sleep disturbances (n = 1,017)

",We note that the causal relations between sleep and depression is an important topic that deserves much further investigation.,"Neural mechanisms linking depressive symptoms with sleep disturbances (n = 1,017)

","Indeed, we note that poor sleep quality also may have an effect on depression, as shown by the mediation analysis. We note that the causal relations between sleep and depression is an important topic that deserves much further investigation. Although previous studies have found changes in patients with depression in some of the regions of interest identified in this study, including the precuneus and angular gyrus, 43 this is to our knowledge the first study to examine the neural mechanisms underlying the associations of depressive problems with sleep quality and to associate sleep quality with functional connectivity in a large sample of participants.","[3.0, 4.0, 5.0, 5.0, 4.0]",Psychology,train,4.2,tweets,1024040814383693825
10.1038/s41598-017-03627-7,Psychology_tweet_56,Social touch increases interpersonal physiological coupling during pain.        ,"Specifically, high women's analgesia as opposed to low analgesia was related to increased coupling between female velocity and male acceleration (Δζ t(p) = 0.015, p < 0.001, 95% CI [0.008, 0.022]) and greater association between male velocity and female acceleration (Δζ t(p) = 0.019, p < 0.001, 95% CI [0.010, 0.028]) in the touch condition.",Social touch increases interpersonal physiological coupling during pain.        ,"As in the case of respiration fluctuations, women's analgesia and touch significantly moderated the effect of cross-partner velocity for heart rate (F (4,13000) = 5.03, p < 0.0001, ΔBIC = −267895.6, ΔR 2 = 0.25). Specifically, high women's analgesia as opposed to low analgesia was related to increased coupling between female velocity and male acceleration (Δζ t(p) = 0.015, p < 0.001, 95% CI [0.008, 0.022]) and greater association between male velocity and female acceleration (Δζ t(p) = 0.019, p < 0.001, 95% CI [0.010, 0.028]) in the touch condition. However, these contrasts were not significant in the no-touch conditions (Δζ nt(p) = 0.003, p = 0.67, males), (Δζ nt(p) = 0.022, p = 0.17, females).","[5.0, 2.0, 2.0, 3.0, 3.0]",Psychology,train,3.0,tweets,877873063303327744
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_57,A neural link between poor sleep and depression:  ,IMPORTANCE Depression is associated with poor sleep quality.,A neural link between poor sleep and depression:  ,IMPORTANCE Depression is associated with poor sleep quality. Understanding the neural connectivity that underlies both conditions and mediates the association between them is likely to lead to better-directed treatments for depression and associated sleep problems. The Depressive Problems score was positively correlated with poor sleep quality (r = 0.371; P < .001).,"[5.0, 5.0, 5.0, 4.0]",Psychology,train,4.75,tweets,1023279421350797312
10.1093/cercor/bhu139,Psychology_tweet_58,"Can you learn Dutch in your sleep? Not quite, but this is close - reactivation study using verbal cues ",Re-exposure to Dutch words during sleep improved later memory for the German translation of the cued words when compared with uncued words.,"Can you learn Dutch in your sleep? Not quite, but this is close - reactivation study using verbal cues ","Re-exposure to Dutch words during sleep improved later memory for the German translation of the cued words when compared with uncued words. Recall of uncued words was similar to an additional group receiving no verbal cues during sleep. Furthermore, verbal cueing failed to improve memory during active and passive waking.","[4.0, 2.0, 4.0, 3.0]",Psychology,train,3.25,tweets,481444783047847936
10.1093/jcr/ucw012,Psychology_tweet_6,"algorithmic reflections of behavior still result in identity shift effects. this paper found that behaviorally targeted advertising can influence self-perceptions through implied social labels
","The results further indicate that while consumers recognize even inaccurate behaviorally targeted ads as implied social labels, it is accuracy (i.e., the match between this prior behavior and the implied label) that determines whether this label is perceived to be relevant to the self, leading to adjustments in self-perceptions that play a mediating role in subsequent trait-related behavior.","algorithmic reflections of behavior still result in identity shift effects. this paper found that behaviorally targeted advertising can influence self-perceptions through implied social labels
","Specifically, we found that labels that are unconnected to prior behavior (i.e., inconsistent with consumers' a priori interest in trait-related products) do not prompt adjustments to self-perceptions and affect behavior; low levels of accuracy yield no effect, whereas moderate to high levels of accuracy produce social labeling effects. The results further indicate that while consumers recognize even inaccurate behaviorally targeted ads as implied social labels, it is accuracy (i.e., the match between this prior behavior and the implied label) that determines whether this label is perceived to be relevant to the self, leading to adjustments in self-perceptions that play a mediating role in subsequent trait-related behavior. Importantly, however, we find that adjustments in consumer self-perceptions in response to behaviorally targeted advertisements depend on the plausibility of the connection between the label and past behavior.","[5.0, 5.0, 2.0, 5.0, 4.0]",Psychology,train,4.2,tweets,939278659445075968
10.1001/jamapsychiatry.2014.1208,Psychology_tweet_61,#PTSD Symptoms &amp; Food #Addiction in Women by Timing and Type of Trauma Exposure  #recoverywarriors #eatingdisorders,Food addiction prevalence appeared to be further elevated when PTSD symptoms occurred earlier in life.,#PTSD Symptoms &amp; Food #Addiction in Women by Timing and Type of Trauma Exposure  #recoverywarriors #eatingdisorders,"In this analysis, we found a dose-response association between the number of lifetime PTSD symptoms and prevalence of food addiction in middle adulthood. Food addiction prevalence appeared to be further elevated when PTSD symptoms occurred earlier in life. To our knowledge, this is the first study to look at the association between PTSD symptoms and food addiction.","[4.0, 2.0, 1.0, 4.0, 3.0]",Psychology,train,2.8,tweets,514060085832978432
10.1001/jamapsychiatry.2017.4249,Psychology_tweet_62,Written exposure therapy and cognitive processing therapy are effective for treatment of #PTSD; PTSD can be effectively treated with a 5-session #psychotherapy.  ,The findings suggest that WET is an efficacious and efficient PTSD treatment that may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers.,Written exposure therapy and cognitive processing therapy are effective for treatment of #PTSD; PTSD can be effectively treated with a 5-session #psychotherapy.  ,"CONCLUSIONS AND RELEVANCE Although WET involves fewer sessions, it was noninferior to CPT in reducing symptoms of PTSD. The findings suggest that WET is an efficacious and efficient PTSD treatment that may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers. 3 Also included in this recommended group of treatments is written narrative exposure, which the clinical practice guideline notes is a simple, yet effective, way to deliver exposure therapy for PTSD.","[4.0, 4.0, 3.0, 5.0, 5.0]",Psychology,train,4.2,tweets,953673280430452736
10.1007/s10926-011-9302-8,Psychology_tweet_63,"@username There was an entire study done on why people don't like to employ, or retain disabled people.  as a result, disabled employees are the ones most likely to be retrenched.","A greater emphasis needs to be placed on communicating to employers that people with disabilities can be effective, productive, and reliable employees; one approach would be to feature employed people with diverse disabilities as trainers or as participants in the training.","@username There was an entire study done on why people don't like to employ, or retain disabled people.  as a result, disabled employees are the ones most likely to be retrenched.","Organizations providing ADA and disability training to managers, supervisors, and human resources personnel need to expand their focus to emphasize not only legal requirements but also problem solving strategies, information resources, and concrete solutions to accommodation and disability issues. A greater emphasis needs to be placed on communicating to employers that people with disabilities can be effective, productive, and reliable employees; one approach would be to feature employed people with diverse disabilities as trainers or as participants in the training. Advice to employers should also include guidance on procedures they could implement to improve the accommodation process and ensure a more hospitable workplace for employees with disabilities.","[1.0, 4.0, 2.0, 3.0, 4.0]",Psychology,train,2.8,tweets,1087120845066067968
10.1111/cdev.12250,Psychology_tweet_65,"New research: ""pseudomature behaviour predicted difficulties in social functioning ten years later"" via @username mag ","Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use.","New research: ""pseudomature behaviour predicted difficulties in social functioning ten years later"" via @username mag ","This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time. Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use. Cumulative continuity theory again suggests an explanation in which early pseudomature behavior may alter critical contexts in which adolescents are developing so as to lead to more serious criminal behavior in the future.","[4.0, 4.0, 5.0, 3.0]",Psychology,train,4.0,tweets,525286095396032512
10.1073/pnas.1311041111,Psychology_tweet_67,Unexpected brain plasticity revealed for the human visual system after cataract removal. ,"Our results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness.",Unexpected brain plasticity revealed for the human visual system after cataract removal. ,"Surprisingly, we find substantial improvement after sight onset in contrast sensitivity, a basic visual function that has well-understood neural underpinnings. Our results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness. Access to this population allowed us to examine contrast sensitivity across a large sample of sight restoration patients compared with previous reports .","[2.0, 3.0, 5.0, 4.0]",Psychology,train,3.5,tweets,431178357213237248
10.1111/add.12373,Psychology_tweet_68,"Do Societal Wealth, Family Affluence &amp; Gender Account for Trends in Teen Marijuana Use? [a]  HT @username","However, gender patterns of consumption and the relationship between societal and family affluence and cannabis use may be changing.","Do Societal Wealth, Family Affluence &amp; Gender Account for Trends in Teen Marijuana Use? [a]  HT @username","However, gender patterns of consumption and the relationship between societal and family affluence and cannabis use may be changing. Across geographical areas and time, adolescent males report higher prevalence of cannabis use compared to females and a greater tendency to abuse and develop dependence on cannabis . Two cultural trends worked in the same direction.","[4.0, 1.0, 3.0, 3.0]",Psychology,train,2.75,tweets,406087714468282368
10.1016/j.sleh.2017.09.004,Psychology_tweet_69,Article: HS start times after 8:30 assoc. w later wake times &amp; longer time in bed amng teens  #FFpubs @username,"Teens starting school at 8:30 AM or later are the only group with an average time in bed permitting 8 hours of sleep, the minimum recommended by expert consensus for health and well-being.",Article: HS start times after 8:30 assoc. w later wake times &amp; longer time in bed amng teens  #FFpubs @username,"Conclusion: Later school start times are associated with later wake times in our large, diverse sample. Teens starting school at 8:30 AM or later are the only group with an average time in bed permitting 8 hours of sleep, the minimum recommended by expert consensus for health and well-being. Data collected from the Youth Risk Behavior Survey in 205 showed that 73% of high school students reported less than 8 hours of sleep on school nights.","[2.0, 3.0, 5.0]",Psychology,train,2.0,tweets,929056102230175745
10.1001/jamapsychiatry.2017.4277,Psychology_tweet_7,Is brain #structuralconnectivity a sensitive transdiagnostic phenotype for predicting psychiatric symptoms in youth? ,"CONCLUSION AND RELEVANCE Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders.",Is brain #structuralconnectivity a sensitive transdiagnostic phenotype for predicting psychiatric symptoms in youth? ,"Both the general psychopathology (16%; SE, 0.095; P = .05) and cognitive (18%; SE, 0.09; P = .01) factor were heritable and showed a negative genetic correlation. CONCLUSION AND RELEVANCE Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders. Whereas the boundaries of this maturational potential are likely regulated by genetic predispositions, experiences and environmental perturbations mediate the individual development of cognitive and mental characteristics.","[5.0, 2.0, 4.0, 4.0, 4.0]",Psychology,train,3.8,tweets,956209985784111104
10.1073/pnas.1505114112,Psychology_tweet_70,"Musical training improves literacy skills in adolescents
 |  ","These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls.","Musical training improves literacy skills in adolescents
 |  ","The music training group also exhibited earlier emergence of the adult cortical response, suggesting that in-school music accelerates neurodevelopment. These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls. Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years.","[3.0, 4.0, 4.0, 5.0]",Psychology,train,4.0,tweets,623400646184714240
10.1177/0141076814565942,Psychology_tweet_71,"""The study of more than 340,000 boys in Denmark found that circumcision raised the overall chances of an autism... ",The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate.,"""The study of more than 340,000 boys in Denmark found that circumcision raised the overall chances of an autism... ","Again, any impact of such exposure misclassification would likely be non-differential, thus contributing to a conservative assessment of the link between circumcision and ASD risk. The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate. Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration.","[4.0, 4.0, 5.0]",Psychology,train,4.333333333333333,tweets,553423370218663937
10.1093/jcr/ucw012,Psychology_tweet_72,We incorporate the segments implied by the behaviorally targeted ads we receive into our view of ourselves ,"The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label.",We incorporate the segments implied by the behaviorally targeted ads we receive into our view of ourselves ,", .0046-.1719), indicating that behavioral targeting increases purchase intentions for the advertised product through the recognition of the implied social label. The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label. Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition).","[5.0, 4.0, 3.0, 4.0, 3.0]",Psychology,train,3.8,tweets,756217822175436800
10.1016/j.jpeds.2017.10.028,Psychology_tweet_73,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59).",Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username  #DV #IPV #VAW #Parenting ,"More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22. A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59). In the multivariate analysis, controlling for sex, ethnicity, age, parental education, yearly alcohol use, as well as child physical abuse, corporal punishment remained a significant and robust predictor of perpetration of dating violence (aOR 1.29, 95% CI 1.02-1.62; Table III) .","[4.0, 4.0, 4.0, 4.0]",Psychology,train,4.0,tweets,955029731111563264
10.1038/s41598-017-03627-7,Psychology_tweet_74,partner's touch reduces pain  by Goldstein et al #pain ,"To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues.",partner's touch reduces pain  by Goldstein et al #pain ,"Finally, reporting pain for both emotional and intensity components may shed more light on our findings. To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues. Although this simplified approach allows analyses of human responses, it lacks the sensitivity to capture elements involved in real-life social interactions.","[4.0, 4.0, 3.0, 4.0, 4.0]",Psychology,train,3.8,tweets,879801682011475968
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_76,"Neural link between poor sleep and depression  this research could lead to better sleep quality for ppl with depression, and opens up the possibility of new targeted treatments!  sleep deprivation is widespread ","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","Neural link between poor sleep and depression  this research could lead to better sleep quality for ppl with depression, and opens up the possibility of new targeted treatments!  sleep deprivation is widespread ","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.","[5.0, 5.0, 5.0, 4.0]",Psychology,train,4.75,tweets,1022632037449191424
10.1001/jamapsychiatry.2018.1941,Psychology_tweet_77,"OBF cortex, DLPF cortex, ant and post cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus. These functional connectivities underlie the association of depressive problem scores with poor sleep quality. ",CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.,"OBF cortex, DLPF cortex, ant and post cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus. These functional connectivities underlie the association of depressive problem scores with poor sleep quality. ","A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality. An important finding was that the Depressive Problems scores in this general population were correlated with functional connectivities between areas, including the lateral orbitofrontal cortex, cingulate cortex, precuneus, angular gyrus, and temporal cortex.","[3.0, 4.0, 4.0, 4.0, 4.0]",Psychology,train,3.8,tweets,1033680011197333504
10.1001/jamapsychiatry.2014.3028,Psychology_tweet_78,#Heritability of #autism #spectrum disorder studies in #UK #twins Study ,We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in UK twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences.,#Heritability of #autism #spectrum disorder studies in #UK #twins Study ,The present study combines the strengths of previous studies and provides a more complete picture than any of them individually by being nationally representative and incorporating dimensional and categorical measures using a systematic repeated screening method. We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in UK twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences. Genetic influences on diagnosed ASD are shared with those on autistic traits in the general population.,"[2.0, 3.0, 4.0, 2.0, 3.0]",Psychology,train,2.8,tweets,573158214897954818
10.1177/0956797618772506,Psychology_tweet_79,The psychological consequences of expressing and receiving gratitude. ,"These results again suggest that expressions of gratitude are guided by expectations about a recipient's reactions, with people choosing to express their gratitude to recipients who they believe will feel positive.",The psychological consequences of expressing and receiving gratitude. ,"Participants choice of whom to write a letter to followed these stated preferences: 31 (32% of the sample) wrote a gratitude letter to the person they expected would feel very positive, 25 (26%) to the person they expected would not feel awkward, 22 (22%) to the person they thought would be really surprised, 16 (16%) to the person they anticipated would not be surprised, 3 (3%) to the person would not feel positive, and only 1 (1%) to the person he or she expected would feel awkward when receiving it. These results again suggest that expressions of gratitude are guided by expectations about a recipient's reactions, with people choosing to express their gratitude to recipients who they believe will feel positive. Finally, participants reported feeling significantly happier than normal after expressing gratitude (M = 2.91, SD = 1.63), one-sample t(97) = 17.72, p < .0001, d = 1.79.","[4.0, 3.0, 3.0, 3.0]",Psychology,train,3.25,tweets,1012677885877014528
10.1073/pnas.1505114112,Psychology_tweet_8,In-school music training in adolescence might accelerate neurodevelopment and improve literacy.   (£),"Phonological awareness improved in both training groups from year 1 to year 4, but these gains were larger in the adolescents who underwent in-school music training.",In-school music training in adolescence might accelerate neurodevelopment and improve literacy.   (£),"An increase in the N1/P1 amplitude ratio from year 1 to year 4, known to emerge in adolescence , was observed in the music group but had not yet emerged in the JROTC group. Phonological awareness improved in both training groups from year 1 to year 4, but these gains were larger in the adolescents who underwent in-school music training. Two other language tests, phonological memory and rapid naming, showed no group differences.","[4.0, 5.0, 4.0, 3.0]",Psychology,train,4.0,tweets,623486828021174272
10.1016/j.nicl.2015.02.009,Psychology_tweet_81,The antiepileptic levetiracetam reduces excess hippocampal activity and improves memory in patients with amnestic MCI ,"Instead, the data support the view that hippocampal overactivity contributes to symptomatic impairment in the MCI phase of disease (for review see Ewers et al., 2011) .",The antiepileptic levetiracetam reduces excess hippocampal activity and improves memory in patients with amnestic MCI ,"Importantly, no evidence was found in this study to support a beneficial compensatory role in cognition for excess hippocampal activation. Instead, the data support the view that hippocampal overactivity contributes to symptomatic impairment in the MCI phase of disease (for review see Ewers et al., 2011) . The deleterious effect of hippocampal overactivity detected by fMRI is further supported by recent evidence of a distinctive gene expression profile underlying excessive hippocampal excitability in MCI patients.","[2.0, 2.0, 5.0, 4.0]",Psychology,train,4.0,tweets,575671721656762368
10.1080/17470919.2016.1257437,Psychology_tweet_82,'Suggesting a mechanism whereby doctrinal concepts may come to be intrinsically rewarding and motivate behavior in religious individuals.' ,Activation of the medial prefrontal cortex in all three tasks may suggest a role in representation of affective meaning for the religious stimuli and suggests that cognitive attribution and judgment of the meaning or value of religious stimuli contributes to their experience.,'Suggesting a mechanism whereby doctrinal concepts may come to be intrinsically rewarding and motivate behavior in religious individuals.' ,The dorsal anterior cingulate cortex in particular may contribute to the perception of salience of religious experience . Activation of the medial prefrontal cortex in all three tasks may suggest a role in representation of affective meaning for the religious stimuli and suggests that cognitive attribution and judgment of the meaning or value of religious stimuli contributes to their experience. A role for the ventromedial prefrontal cortex in shaping belief is also supported by evidence that neuromodulation of this regions can specifically decrease endorsement of religious beliefs .,"[4.0, 4.0, 4.0, 3.0, 3.0]",Psychology,train,3.6,tweets,803569840933859329
10.1093/schbul/sbx158,Psychology_tweet_83,New paper led by @username links #cannabis and features of #bipolardisorder in young adults from @username cohort ,"Consistent with the stage specific model of mental disorders linking intervention to stage of illness, our findings suggest frequent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder.",New paper led by @username links #cannabis and features of #bipolardisorder in young adults from @username cohort ,"The study also identifies cannabis use as a candidate mechanism for explaining how childhood abuse may lead to hypomania in adulthood. This is important in the context of the push in many jurisdictions to legalize or decriminalize cannabis. Consistent with the stage specific model of mental disorders linking intervention to stage of illness, our findings suggest frequent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder.","[4.0, 4.0, 2.0, 4.0]",Psychology,train,3.5,tweets,936502789387227136
10.1007/s10508-017-0962-0,Psychology_tweet_84,Perceived gay or lesbian vocal stereotypes = less likely to be hired/promoted  (paper: ,"Behavioral intention measures showed that listeners considered lesbian and gay speakers as less suitable for a leadership position, and male (but not female) listeners took distance from gay speakers.",Perceived gay or lesbian vocal stereotypes = less likely to be hired/promoted  (paper: ,"In all four studies, listeners were found to make gender-typical inferences about traits and preferences of heterosexual speakers, but gender-atypical inferences about those of gay or lesbian speakers. Behavioral intention measures showed that listeners considered lesbian and gay speakers as less suitable for a leadership position, and male (but not female) listeners took distance from gay speakers. Together, this research demonstrates that having a gay/ lesbian rather than heterosexual-sounding voice has tangible consequences for stereotyping and discrimination.","[3.0, 3.0, 4.0, 3.0]",Psychology,train,3.25,tweets,846027192190586880
10.1073/pnas.1601443113,Psychology_tweet_85,Early childhood maternal support on hippocampal volume growth is associated with later emotion functioning ,"In contrast to preschool support, there was no significant change in total hippocampus volume over time as a function of school-age maternal support (B = −0.0001, SE = 0.0011, t = −0.10, P = 0.9228).",Early childhood maternal support on hippocampal volume growth is associated with later emotion functioning ,"S1 shows estimated trajectories of total hippocampus volume by preschool maternal support. In contrast to preschool support, there was no significant change in total hippocampus volume over time as a function of school-age maternal support (B = −0.0001, SE = 0.0011, t = −0.10, P = 0.9228). The school-age maternal support by time interaction in that model was still not significant (B = 0.0012, SE = 0.0011, t = 1.12, P = 0.2647).","[3.0, 3.0, 2.0, 2.0]",Psychology,train,2.5,tweets,725330212800573441
10.1038/s41598-018-30980-y,Psychology_tweet_88,"In a new study by sleep researchers at @username, neuroscientists led by @username report for the first time evidence that #naps and overnight #sleep may work together to benefit memory in early childhood.  ","For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 .","In a new study by sleep researchers at @username, neuroscientists led by @username report for the first time evidence that #naps and overnight #sleep may work together to benefit memory in early childhood.  ","If such were the case, REM in subsequent overnight sleep may support delayed emotional memory processing. For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep 7 . Likewise, negative memories selectively cued during SWS are better remembered than uncued items 8 .","[3.0, 3.0, 3.0, 3.0, 2.0]",Psychology,train,2.8,tweets,1032306068595134465
10.1001/jamapsychiatry.2013.4081,Psychology_tweet_89,Association between older fatherhood and psychotic illness in children ,"In contrast, paternal age showed a U-shaped relationship, with the offspring of teenaged fathers having a 28% increased risk for a psychiatric disorder (IRR, 1.28 [95% CI, 1.24-1.32]), whereas the offspring of the fathers 45 years or older had a 34% increased risk (1.34 [1.30-1.39]).",Association between older fatherhood and psychotic illness in children ,"No significantly increased risk for the offspring of older mothers was found. In contrast, paternal age showed a U-shaped relationship, with the offspring of teenaged fathers having a 28% increased risk for a psychiatric disorder (IRR, 1.28 [95% CI, 1.24-1.32]), whereas the offspring of the fathers 45 years or older had a 34% increased risk (1.34 [1.30-1.39]). Figure 1 shows the relationship between maternal and paternal ages and the risk for any mental disorder when not adjusted and when adjusted for age of the other parent.","[3.0, 2.0, 4.0, 4.0]",Psychology,train,3.25,tweets,433676530326462464
10.1001/jamapsychiatry.2017.4271,Psychology_tweet_9,Tobacco and Cannabis Use in Adolescence and Their Association With Psychotic Experiences ,"CONCLUSIONS AND RELEVANCE In this study, our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use.",Tobacco and Cannabis Use in Adolescence and Their Association With Psychotic Experiences ,"After adjusting for confounders, the association for early-onset cigarette-only use attenuated substantially (unadjusted odds ratio [OR], 3.03; 95% CI, 1. adjusted OR, 1.78; 95% CI,), whereas those for early-onset cannabis use (adjusted OR, 3.70; 95% CI, 1.66-8.25) and late-onset cannabis use (adjusted OR, 2.97; 95% CI, 1.63-5.40) remained consistent. CONCLUSIONS AND RELEVANCE In this study, our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use. Individuals who use cannabis regularly have a 2-to 3-fold increased risk of a psychotic outcome.","[4.0, 4.0, 3.0, 4.0, 3.0]",Psychology,train,3.6,tweets,987179036563595264
10.1001/jamapsychiatry.2018.3514,Psychology_tweet_90,"""Individuals with psychotic experiences are at increased risk of suicidal ideation, suicide attempts, and suicide death""  ""Psychotic experiences are important clinical markers of risk for future suicidal behavior"" See also: ","Using a convergent functional genomics approach, Niculescu et al [54] [55] [56] showed that many of the top biomarkers for suicide are also biomarkers for psychotic disorders and high hallucination states.","""Individuals with psychotic experiences are at increased risk of suicidal ideation, suicide attempts, and suicide death""  ""Psychotic experiences are important clinical markers of risk for future suicidal behavior"" See also: ","In the context of high stress and poorer communication skills, this might adversely affect the individual's ability to formulate logical plans to manage perceived challenges and instead increase the likelihood of turning to suicide. Using a convergent functional genomics approach, Niculescu et al [54] [55] [56] showed that many of the top biomarkers for suicide are also biomarkers for psychotic disorders and high hallucination states. A notable strength of the review is that we used longitudinal studies, which established a temporal association between PEs and suicidal behavior.","[3.0, 3.0, 4.0, 3.0, 3.0]",Psychology,train,3.2,tweets,1067849528412422144
10.1038/s41598-018-30980-y,Psychology_tweet_91,Learning a lot about sleep from @username. Naps and sleep are very important for young children to enhance emotional memory. Even more reasons for a daytime siesta. ,"Notably, here too with emotional memories, we found a significant association between ΔRecall nap and ΔRecall overnight such that declines in accuracy across the nap were associated with improvements across overnight sleep (B = −0.488, p = 0.029; 95% CI: [−1.294, −0.079]; Fig.",Learning a lot about sleep from @username. Naps and sleep are very important for young children to enhance emotional memory. Even more reasons for a daytime siesta. ,"In that study, ΔRecall nap predicted ΔRecall overnight , suggesting an interaction of multiple sleep bouts on memory processing. Notably, here too with emotional memories, we found a significant association between ΔRecall nap and ΔRecall overnight such that declines in accuracy across the nap were associated with improvements across overnight sleep (B = −0.488, p = 0.029; 95% CI: [−1.294, −0.079]; Fig. We did not receive caregiver reports for 9 of the children.","[4.0, 3.0, 5.0, 3.0, 3.0]",Psychology,train,3.6,tweets,1038112531238346753
10.1177/0141076814565942,Psychology_tweet_92,A new study shows that Circumcision more than doubles the risk of autism... ,"As with the missing circumcisions performed by religious circumcisers, such non-differential exposure misclassification will most likely produce conservative estimates of any real difference in ASD risk between circumcised and intact boys.",A new study shows that Circumcision more than doubles the risk of autism... ,"Our HR estimates for ASD are therefore most likely conservative. As with the missing circumcisions performed by religious circumcisers, such non-differential exposure misclassification will most likely produce conservative estimates of any real difference in ASD risk between circumcised and intact boys. Reassuringly, our robustness analysis in which we restricted the observation period to 1994-2003, when ritual circumcisions and ASD outcomes were covered, revealed a stronger association of ritual circumcision with ASD risk (HR ¼ 1.62) than in the main analysis (HR ¼ 1.46).","[2.0, 5.0, 4.0, 3.0]",Psychology,train,3.5,tweets,553412707559698435
10.1093/jcr/ucw012,Psychology_tweet_93,We incorporate into our identity the identities suggested by our behaviorally targeted ads  ,"Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions.",We incorporate into our identity the identities suggested by our behaviorally targeted ads  ,"Participants in the demographically targeted condition recognized an implied label marginally more than those in the nontargeted condition (F(1, 185) ¼ 3.06, p ¼ .08, g 2 ¼ .02). Thus, as expected, consumers in the behaviorally targeted ad condition recognized that the ad implied a social label to a greater extent than those in the other conditions. An ANOVA on purchase intentions for the restaurant Groupon revealed a significant difference between the conditions (F(2, 185) ¼ 3.81, p < .05, g 2 ¼ .04).","[3.0, 3.0, 3.0, 5.0]",Psychology,train,3.5,tweets,716071160404975616
10.1016/j.jpeds.2017.10.028,Psychology_tweet_94,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth.,Childhood Corporal #Punishment and Future Perpetration of Physical Dating Violence [a]  HT @username #DV #IPV #VAW #Parenting ,"(J Pediatr 2018;194:233-7). Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth. 9 These factors cut across various domains including affective (eg, emotion dysregulation, psychiatric disorder), cognitive (eg, attitudes toward women, beliefs about violence), demographic (eg, age, race, sex, sexual orientation, socioeconomic status), interpersonal (eg, relationship satisfaction, problem solving skills), contextual (eg, availability of weapon, drug/alcohol use), as well as distal factors (eg, history of child abuse, exposure to family violence).","[2.0, 2.0, 1.0, 3.0, 2.0]",Psychology,train,2.0,tweets,940635013313449985
10.1038/s41598-017-03627-7,Psychology_tweet_95,Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"Interestingly, the difference in pain between the conditions with and without touch was higher in females than in males, who estimated their partners' pain.",Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"Nevertheless, the moderation effects of empathic accuracy and pain analgesia reduce the probability of this explanation. Interestingly, the difference in pain between the conditions with and without touch was higher in females than in males, who estimated their partners' pain. These findings can be explained by the fact that female participants experienced the real pain and their male partners only guessed the females' pain level.","[1.0, 3.0, 3.0, 2.0, 5.0]",Psychology,train,2.0,tweets,885195850477187077
10.1038/s41598-017-03627-7,Psychology_tweet_96,"Touch could help us feel the pain of others, study. I wonder if this works to tell real pain vs faked pain. 

",The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain.,"Touch could help us feel the pain of others, study. I wonder if this works to tell real pain vs faked pain. 

","Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling. The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain. This indicates that coupling .","[5.0, 3.0, 3.0, 5.0]",Psychology,train,4.0,tweets,892101559441649664
10.1038/s41598-017-03627-7,Psychology_tweet_97,Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 .",Role of touch in regulating inter-partner physiological coupling during #empathy for #pain  MT @username ,"This complicated physiological mechanism may underlie the observed coupling between the partners. It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 . Thus, future research should test the role of oxytocin in touch-related analgesia.","[3.0, 3.0, 1.0, 2.0, 1.0]",Psychology,train,2.0,tweets,877405828088815616
10.1001/jamapsychiatry.2018.1941,Psychology_easy_4,The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality.,CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality.,"The analysis showed that these functional connectivities underlie the relation between depressive problems and sleep quality. The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","A mediation analysis showed that these functional connectivities underlie the association of the Depressive Problems score with poor sleep quality (β = 0.0139; P < .001). CONCLUSIONS AND RELEVANCE The implication of these findings is that the increased functional connectivity between these brain regions provides a neural basis for the association between depression and poor sleep quality. An important finding was that the Depressive Problems scores in this general population were correlated with functional connectivities between areas, including the lateral orbitofrontal cortex, cingulate cortex, precuneus, angular gyrus, and temporal cortex.",[5],Psychology,train,5.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1111/cdev.12250,Psychology_easy_5,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.","By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","This study found that a constellation of pseudomature behaviors in early adolescence predicted significant difficulties in social functioning up to 10 years later, in early adulthood. The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence. The early adolescent behaviors examined-minor forms of delinquency, early romantic behavior, and a focus on physical appearance in seeking out friends-are often considered to be nearly normative and only modestly problematic aspects of adolescence, and are widespread by mid-adolescence ; however, when they appear early in adolescence, these seemingly minor Criminal behavior (ages 21-23)",[5],Psychology,train,5.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1177/0141076814565942,Psychology_easy_6,"""Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority,"" the study suggested.","Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority.","""Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority,"" the study suggested. The study has also prompted the American Academy of Pediatrics to release a statement advising health facilities for newborns to use strategies that would lessen the number of painful procedures performed. Experts Are Divided On Frisch's Study

Not all experts are convinced with Frisch's study that suggests circumcision could increase autism risk.","This finding, and the unexpected observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families, need attention, particularly because data limitations most likely rendered our HR estimates conservative. Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority. Among children operated for a variety of conditions, Levy noted a strong association between the age at operation and the frequency and severity of emotional sequelae.",[5],Psychology,train,5.0,news,http://www.parentherald.com/articles/44740/20160519/circumcision-increase-autism-risk-experts-divided.htm
10.1007/s13524-014-0321-x,Psychology_easy_8,"Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below.","Older parents, between the ages of 35 -- 49, have the strongest happiness gains around the time of birth and stay at a higher level of happiness after becoming parents. Those who become parents in their teens have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents between the ages of 23 -34 have increasing happiness before a first birth, however one to two years after the birth, happiness decreases to baseline or below.","Young parents have a predominantly declining pattern of happiness that does not increase above the baseline even during the year of birth. Those who become parents at ages 23-34 have increasing happiness before a first birth and in the year of birth; however, one to two years after the birth, happiness decreases to baseline or below. Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0956797617692041,Psychology_easy_9,"""Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption,"" the researchers write.","Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption.","But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves. ""Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption,"" the researchers write. ""However, requiring the participants to stand up and walk a tiny distance to obtain their refills helped to curb it.""","The intent-to-treat analysis was statistically weaker than the analysis of just those participants who bought a drink because it was conservative, especially considering that (a) the manipulation pertained only to large-drink orders, which were placed by only 25.3% of the sample, and (b) it excluded drink size as an explanatory variable-and drink size, not surprisingly, explained considerable variance. Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption. However, requiring the participants to stand up and walk a tiny distance to obtain their refills helped to curb it.",[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1038/s41598-018-30980-y,Psychology_easy_11,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.",Greater nap slow wave activity was associated with greater memory decay during the nap.,"However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day. Greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1038/s41598-018-30980-y,Psychology_easy_13,"Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report.",Change in memory accuracy also did not differ when probed after a nap compared to the change in memory accuracy after an interval awake.,"To do this, they presented children ages approximately three to five years (34-64 months) with faces paired with mean or nice word descriptions, but they saw no significant main effects of emotional valence on recognition memory. Change in memory accuracy also did not differ when tested after a nap compared to the change in memory accuracy after an interval awake, they report. However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day.","There were no significant main effects of emotional valence on recognition memory. Change in memory accuracy also did not differ when probed after a nap compared to the change in memory accuracy after an interval awake. However, when memory was probed again following overnight sleep, the change in memory accuracy was greater if the child napped the previous day.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s10508-017-0962-0,Psychology_easy_15,"While wead like to think all workplaces practice inclusive and progressive policies centered around LGBTQ communities, thatas far from reality.","Behavioral intention measures showed that listeners considered lesbian and gay speakers as less suitable for a leadership position, and male (but not female) listeners took distance from gay speakers.","While wead like to think all workplaces practice inclusive and progressive policies centered around LGBTQ communities, thatas far from reality. aTransitioning in the Workplacea shares advice about coming out to colleagues, introducing a new name and setting a medical timeline with your manager. It might get a little uncomfortable at work.","In all four studies, listeners were found to make gender-typical inferences about traits and preferences of heterosexual speakers, but gender-atypical inferences about those of gay or lesbian speakers. Behavioral intention measures showed that listeners considered lesbian and gay speakers as less suitable for a leadership position, and male (but not female) listeners took distance from gay speakers. Together, this research demonstrates that having a gay/ lesbian rather than heterosexual-sounding voice has tangible consequences for stereotyping and discrimination.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37397496941&p=1pl&v=1&x=Pw4ndUhTRs2bbpeJxg_bxQ
10.1093/jcr/ucw012,Psychology_easy_16,"""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said.","First, we provide an early inquiry into the effects of behaviorally targeted ads.","The participants who were targeted because of their demographic characteristics were not more likely to purchase the Groupon compared to participants who did not think the ad was targeted. ""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said. When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer.","Our findings offer several important theoretical contributions. First, we provide an early inquiry into the effects of behaviorally targeted ads. We identify how behavioral targeting is distinct from traditional forms of targeting and empirically demonstrate the conditions under which these characteristics prompt unique psychological consequences for consumers.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1016/j.jpeds.2017.10.028,Psychology_easy_17,My preference is to encourage positive behavioral management and decrease the use of punishment.,"More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.","As a psychologist, I find this to be a frequent topic of conversation and debate with parents. My preference is to encourage positive behavioral management and decrease the use of punishment. Punishment like spanking doesn't improve a child's behavior over the long-term.","There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22. A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32818256385&p=1pl&v=1&x=0ZAEkx105k29I5f3n6_nlQ
10.1186/2045-5380-3-19,Psychology_easy_19,"And, CBD would also provide them with a means to improve their focus without taking illicit drugs.","For example, acute administration of the CB1 receptor antagonists SR141716 or AM251 increase anxiety-like behavior in several behavioral measures, including the elevated plus-maze , novelty-induced hypophagia assay , social interaction test , light-dark box assay and ultrasonic vocalization assay .","This means that CBD could provide an effective way to help Adderall abusers overcome their addiction. And, CBD would also provide them with a means to improve their focus without taking illicit drugs. Switch Adderall for CBD Today

As the best alternative to Adderall, CBD offers an effective solution, both for those taking Adderall for ADHD and for those abusing it for its stimulant properties.","Interestingly, targeted deletion of CB1 from serotonergic neurons alone seems to recapitulate the anxiety phenotype of global CB1−/− mice . For example, acute administration of the CB1 receptor antagonists SR141716 or AM251 increase anxiety-like behavior in several behavioral measures, including the elevated plus-maze , novelty-induced hypophagia assay , social interaction test , light-dark box assay and ultrasonic vocalization assay . For example, a CB1 receptor antagonist reduced anxiety in the elevated plus-maze in maze-experienced mice , reduced some signs of anxiety in the defensive probe burying assay and reduced anxiety associated with alcohol withdrawal .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1186/s13229-018-0246-0,Psychology_easy_21,"In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China.","Of the 6149 screened children from mainstream schools whose data were available for analysis (step 1), 477 (7.8%) were in the high-score group on the CAST (≥ 15), 745 (12.1%) were in the borderline group , and 4927 (80.1%) were in the low-score group (≤ 11).","In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000. In all three cities, the researchers identified new cases of autism in mainstream schools, confirming that there is under-diagnosis of autism in China. ""Contrary to previous studies, we have shown that the prevalence of autism spectrum conditions in China is in line with that found in the West,"" said Dr Sophia Xiang Sun, who conducted this study as part of her PhD at Cambridge University and who is now based in the Star Kay Bridge Research Centre for Children with Autism in Xiamen, China.","The median score on the CAST was 8 (IQR 5, 11; range 0, 23). Of the 6149 screened children from mainstream schools whose data were available for analysis (step 1), 477 (7.8%) were in the high-score group on the CAST (≥ 15), 745 (12.1%) were in the borderline group , and 4927 (80.1%) were in the low-score group (≤ 11). All 477 children in the high-score group completed the clinical assessment (step 2) (participation rate = 100%).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1007/s13524-014-0321-x,Psychology_easy_22,Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.,"The main difference is that German parents have similar happiness trajectories, whether partnered or unpartnered; in Britain, however, partnered parents experience larger increases in happiness in response to a birth than the unpartnered.","Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children. Younger parents, on the other hand, are more prone to post-birth depression.","Our results are quite similar in Britain and Germany. The main difference is that German parents have similar happiness trajectories, whether partnered or unpartnered; in Britain, however, partnered parents experience larger increases in happiness in response to a birth than the unpartnered. These differences may reflect differences in the social stigma related to out-of-wedlock childbearing and single parenthood.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1111/cdev.12250,Psychology_easy_23,One thing to note is that this was a relatively small study.,"This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study. One thing to note is that this was a relatively small study. Though participants were from both urban and suburban areas, 184 kids can't be enough to be totally sure about widespread patterns.","One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time. Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1093/jcr/ucw012,Psychology_easy_24,"""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said.",Recall that our theoretical model proposes that consumers' response to behaviorally targeted ads is a conscious process involving recognition that the ad being delivered to them is being shown because of a marketer's inference about their identity.,"The participants who were targeted because of their demographic characteristics were not more likely to purchase the Groupon compared to participants who did not think the ad was targeted. ""The targeting has to be based on your behavior and not just demographic attributes such as age or gender,"" Smith said. When the targeting is based on behavior, consumers believe the advertiser is labeling them as a particular type of consumer: a sophisticated consumer, or a green consumer.",The ad in the other two conditions was presented without this information and did not include the AdChoices icon. Recall that our theoretical model proposes that consumers' response to behaviorally targeted ads is a conscious process involving recognition that the ad being delivered to them is being shown because of a marketer's inference about their identity. This awareness of being characterized by an external agent is a key distinction between our proposed process and the process that occurs when an identity is made internally salient.,[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/nn.3635,Psychology_easy_25,come closer to characterizing the dynamic emergence of representational geometries across stages of processing in humans than any previous work.,This analysis allows identifying the cortical sources that have persistent neural activity.,"""The combination of MEG and fMRI in humans is no surrogate for invasive animal studies with techniques that simultaneously have high spatial and temporal precision, but Cichy et al. come closer to characterizing the dynamic emergence of representational geometries across stages of processing in humans than any previous work. The approach will be useful for future studies elucidating other perceptual and cognitive processes,"" says Kriegeskorte, who was not part of the research team.","Relating MEG and fMRI object signals across time The above MEG-fMRI representational similarity analysis naturally extends to include the MEG time-time decoding matrices constructed earlier (Fig. This analysis allows identifying the cortical sources that have persistent neural activity. We therefore correlated the fMRI dissimilarity matrices of V1 and IT with the MEG 92 × 92 decoding matrices obtained for each pair of time points (t x ,t y ) ( Figs.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_easy_26,Allen and his team found evidence to suggest that this behavior might actually hurt social status in school.,"However, over the following years, pseudomature behavior was associated with a significant relative decline in levels of popularity.","The reason these ""cool"" kids are lost at sea as adults isn't karma working its magic -- it's more scientific than that. Allen and his team found evidence to suggest that this behavior might actually hurt social status in school. When it ended, they were 23.","Results, presented in Table 2 , based on a highly significant overall linear growth model, v 2 (3) = 249.5, p < .001, indicate that pseudomature behavior was associated with higher levels of popularity among peers at age 13, as predicted. However, over the following years, pseudomature behavior was associated with a significant relative decline in levels of popularity. This indicates that, as hypothesized, pseudomature behavior was indeed linked to higher status with peers early in adolescence, but that as development progresses and peers mature, this link steadily fades out, and was no longer present by age 15 (see Figure 1) .",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1016/j.jalz.2018.06.2856,Psychology_easy_27,"The results offer physicians a new way to detect those at higher risk of this disorder, which causes memory loss and other symptoms of cognitive decline.",Several hypotheses may explain our findings.,"The results offer physicians a new way to detect those at higher risk of this disorder, which causes memory loss and other symptoms of cognitive decline. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions.","Future investigations that assess associations between AD and DR severity will be important. Several hypotheses may explain our findings. First, it may seem tempting to dismiss these findings as age-related phenomena.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1038/s41598-017-18902-w,Psychology_easy_28,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","Figure 7A shows their R-parameter results: 17 out of 20 parents (10 out of 13 mothers, and all fathers) fell in the ASD R-region, having lower R-values than TD adults.","The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism.","The high heterogeneity of ASD symptomatic behaviors, even in affected siblings 42 , impedes a clear identification of generic genetic filial links. Figure 7A shows their R-parameter results: 17 out of 20 parents (10 out of 13 mothers, and all fathers) fell in the ASD R-region, having lower R-values than TD adults. ASD Parents available are generally older than the TD adults tested, aging from 30 to 60 years old.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1093/jcr/ucw012,Psychology_easy_29,"Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences.""","As expected, the effect of behavioral targeting on donation amount was mediated by the labeling index in the environmentally friendly condition (b ¼ .17, SE ¼ .12, 95% CI, .0079-.4907) but not in the control condition (b ¼ .11, SE ¼ .09, 95% CI, À.0142 to .3684).","""In a sense, you become more like what the ads say you are. Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences."" They were also more likely to say they would purchase the Groupon than those in the other two groups.","The analyses revealed that self-perceptions of greenness significantly mediated the effect of behavioral targeting on purchase intentions when the speaker was positioned as environmentally friendly (b ¼ .14, SE ¼ .06, 95% CI, .0396-.2932) but not in the control positioning condition (b ¼ À.06, SE ¼ .07, 95% CI, À.2011 to .0682). As expected, the effect of behavioral targeting on donation amount was mediated by the labeling index in the environmentally friendly condition (b ¼ .17, SE ¼ .12, 95% CI, .0079-.4907) but not in the control condition (b ¼ .11, SE ¼ .09, 95% CI, À.0142 to .3684). The analysis revealed that self-perceptions significantly mediated the effect of behavioral targeting on donation amount when the speaker was positioned as environmentally friendly (b ¼ .25, SE ¼ .12, 95% CI, .0685-.5482) but not in the control condition (b ¼ À.10, SE ¼ .13, 95% CI, À.4455 to .0980).",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/s41598-017-03627-7,Psychology_easy_30,""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being.","That is, we observed a shift from exhalation to inhalation in a participant when their partner inhales (the heart rate shifts from a decrease to an increase when the partner exhibited an increase in heart rate).",""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being. They probably had no idea that their poppy little ditty had a basis in scientific fact. That's almost as many as the entire population of Texas.","The results show that both empathic accuracy and trait empathy moderated inter-partner physiological coupling, so that dyads with highly empathic male partners demonstrated increased coupling. That is, we observed a shift from exhalation to inhalation in a participant when their partner inhales (the heart rate shifts from a decrease to an increase when the partner exhibited an increase in heart rate). Moreover, in the couples where the female partners reported greater touch-related analgesia, we observed enhanced physiological coupling.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1080/08870446.2013.818674,Psychology_easy_32,Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good.,"Numbers of cigarettes smoked at Tl , however, were not related to any known mechanism.","Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette). Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good. When occurring on their own, self-efficacy, coping strategies and social support did not increase the chances of quitting.","At T2, the variables assessing smoking cessation showed 7.5% missing values. Numbers of cigarettes smoked at Tl , however, were not related to any known mechanism. The rationale lies in the sample size, as samples with about 100 participants have limited power for detecting moderation effects (see e.g.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41598-017-03627-7,Psychology_easy_33,""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being.","Moreover, tactile-induced analgesia 66 correlates with activations in brain areas related to multimodal neural activity 67 and emotional processes .",""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being. They probably had no idea that their poppy little ditty had a basis in scientific fact. That's almost as many as the entire population of Texas.","It seems that this phenomenon has evolutionary roots. Moreover, tactile-induced analgesia 66 correlates with activations in brain areas related to multimodal neural activity 67 and emotional processes . The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 .",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1016/j.jalz.2018.06.2856,Psychology_easy_34,"""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss.""","model adjusted for smoking, we had a much longer followup, and including cerebrovascular disease did not change the strength of association between AMD and AD risk.","That's a correlation that's well worth investigating further. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Eye checkups could be used to screen people with a greater risk of Alzheimer's perhaps - and while there's no cure yet, appropriate care could be provided earlier.","The Rotterdam Study followed 1438 dementia-free participants aged 75 years for an average of 25 months and found increased AD risk in those with advanced AMD (HR 2.1, [1.1, 4.3] ), but this became insignificant with smoking and atherosclerosis included in the model . model adjusted for smoking, we had a much longer followup, and including cerebrovascular disease did not change the strength of association between AMD and AD risk. A study of the Taiwan National Health Insurance Research Database showed a HR of 1.44 (1.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1001/jamapsychiatry.2018.1941,Psychology_easy_35,"Feng comments that these findings could have important public health implications, as both sleep problems and depression affect a large number of people.","Notably, 92 participants (9.0%) had been diagnosed with a major depressive episode (as defined by the DSM-IV)o v er their lifetimes.","""This important cross-validation with participants from the USA provides support for the theory that the lateral orbitofrontal cortex is a key brain area that might be targeted in the search for treatments for depression."" Feng comments that these findings could have important public health implications, as both sleep problems and depression affect a large number of people. The findings appear in JAMA Psychiatry.","Further details are in eTable 2oftheSupplement. Notably, 92 participants (9.0%) had been diagnosed with a major depressive episode (as defined by the DSM-IV)o v er their lifetimes. These participants had a significantly mean (SD) higher score (7.55 [4.83] points) than the other participants (3.70 [3.07] points; t 982 =−10.8;P < .001) on the Depressive Problems scale.",[1],Psychology,train,1.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1016/j.nicl.2015.02.009,Psychology_easy_36,Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task.,"Overactivity in areas of activation localized anterior to posterior, as reported here and elsewhere in the context of the 3-judgment recognition task could reflect a relatively greater contribution of augmented pattern completion in anterior areas of activation with any excess activation reflecting a loss of pattern separation in DG contributing more in posterior areas of activation.","""At the same time, it improves memory performance on a task that depends on the hippocampus."" Researchers found low doses both improved memory performance and normalized the over-activity detected by functional magnetic resonance imaging that measures brain activity during a memory task. The ideal dosing found in this clinical study matched earlier preclinical studies in animal models.","Of possible relevance in the current context noted a relatively greater proportion of CA fields (CA1-3) in the anterior hippocampal formation with the DG having a proportionately greater representation at the posterior segments of the long axis. Overactivity in areas of activation localized anterior to posterior, as reported here and elsewhere in the context of the 3-judgment recognition task could reflect a relatively greater contribution of augmented pattern completion in anterior areas of activation with any excess activation reflecting a loss of pattern separation in DG contributing more in posterior areas of activation. Overall, however, these findings suggest that excess fMRI activation in the DG/CA3 is associated with a consistent profile of memory task impairment across all three aMCI cohorts.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1111/lcrp.12013,Psychology_easy_37,"However, participants who had built a rapport said that they felt more comfortable when they closed their eyes.","Nevertheless, from an applied point of view, the finding that eye-closure was, if anything, more effective after a week and a previous recall attempt is promising.","Participants who had not built a rapport with their interrogator said that they felt uncomfortable closing their eyes in both experiments. However, participants who had built a rapport said that they felt more comfortable when they closed their eyes. ""It is clear from our research that closing the eyes and building rapport help with witness recall.","To examine the individual contributions of delay and repeated recall, respectively, future research should disentangle these effects. Nevertheless, from an applied point of view, the finding that eye-closure was, if anything, more effective after a week and a previous recall attempt is promising. Therefore, the simple eye-closure instruction could be a useful addition to the investigative interviewer's tool box, particularly in cases in which time is limited.",[1],Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1111/cdev.12250,Psychology_easy_38,"""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said.","With respect to alcohol and marijuana use, early adolescent pseudomature behavior was actually a better predictor of future such substance use problems in adulthood than were even early adolescent levels of such use.","By 22, the cool kids struggled to make friends. ""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.","More importantly, early adolescent pseudomature behavior had value in predicting future criminal behavior and alcohol and marijuana use problems over and above early adolescent markers of such problems. With respect to alcohol and marijuana use, early adolescent pseudomature behavior was actually a better predictor of future such substance use problems in adulthood than were even early adolescent levels of such use. In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time .",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1111/cdev.12250,Psychology_easy_39,"""It appears that while so-called cool teens' behavior might have been linked to early popularity, over time, these teens needed more and more extreme behaviors to try to appear cool,"" Joseph P. Allen, lead author and professor of psychology at the University of Virginia, said in statement.",One critical qualification to these findings is that they applied to pseudomature behaviors assessed in early adolescence.,"They may be cool now, but see what happens in 10 years. ""It appears that while so-called cool teens' behavior might have been linked to early popularity, over time, these teens needed more and more extreme behaviors to try to appear cool,"" Joseph P. Allen, lead author and professor of psychology at the University of Virginia, said in statement. At 13, those who exhibited ""pseudomature behaviors"" -- a catchall term for behaviors that seem to boost perceived popularity -- were rated as more popular by their peers.","In either case, these findings make clear that the status-seeking aspect of early adolescent pseudomature behavior displays long-term continuity that extends into a new and important relationship domain even across a span of nearly a decade. One critical qualification to these findings is that they applied to pseudomature behaviors assessed in early adolescence. This is important, because by mid-to late-adolescence, the behaviors assessed become common enough that long-term links to problematic outcomes become far less likely.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1111/cdev.12250,Psychology_easy_40,"Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.","Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence.","""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study. One thing to note is that this was a relatively small study.","5. Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence. Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1007/s13524-014-0321-x,Psychology_easy_41,This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small.,This may diminish the differences in the well-being trajectories in Germany between the partnered and unpartnered when compared with the difference in Britain.,"""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report. This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small. The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby.",These differences may reflect differences in the social stigma related to out-of-wedlock childbearing and single parenthood. This may diminish the differences in the well-being trajectories in Germany between the partnered and unpartnered when compared with the difference in Britain. Differences in the tax and family policies available for lone parents may also contribute to the country differences.,[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1186/2045-5380-3-19,Psychology_easy_42,"As such, the potential CBD shows as the most effective natural alternative to Adderall is very significant.","Taken together, while the effects of CB1 receptor antagonism or deletion may be equivocal with respect to behavioral tests of stress coping, which is reflective of depressive behavior, there is a high degree of consistency among reports demonstrating that inhibition of FAAH produces antidepressant-like effects in rodent models.","As such, the potential CBD shows as the most effective natural alternative to Adderall is very significant. It works by heightening CNS connections to control hyperactivity and impulses. This, in turn, helps improve focus and attention in those with ADHD.","This is a critical question as it may reveal a second molecular target for the pharmacological targeting eCB signaling to give an antidepressant effect. Taken together, while the effects of CB1 receptor antagonism or deletion may be equivocal with respect to behavioral tests of stress coping, which is reflective of depressive behavior, there is a high degree of consistency among reports demonstrating that inhibition of FAAH produces antidepressant-like effects in rodent models. Similarly, chronic restraint stress-induced anxiety behaviors in the elevated plus-maze is augmented in CB1−/− mice, as is the stress-induced dendritic hypertrophy in the amygdala .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1073/pnas.1702671114,Psychology_easy_44,"Their high-frequency chirps, undetectable to the human ear, are quick and precise.","One important parameter returned by the model is the response latency of about 30 ms, which is remarkably short.","Unlike humans, whose vocalizations are comparatively long and slow, bats are ideal for such a sensorimotor study. Their high-frequency chirps, undetectable to the human ear, are quick and precise. The white noise interfered with the bat's echolocation and caused it to emit louder and louder chirps, not unlike someone trying to be heard, first over a loud radio, then over a lawn mower, and then over the siren's blare from a passing fire engine.","Thus, the differences in the vocal amplitude compensation between the 40-and 50-dB noise conditions were driven nearly entirely by the third parameter, the maximum increase in call amplitude (5.9 dB vs. 9.8 dB). One important parameter returned by the model is the response latency of about 30 ms, which is remarkably short. 4 C-J shows that the model accounts for the data from the other eight experimental conditions quite well.",[1],Psychology,train,1.0,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1093/jcr/ucw012,Psychology_easy_45,"When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color.","Revealed preferences are ""revealed"" by observing actual choice (vs. simply asking consumers to state their preferences).","Some of this research hints at the memory-distorting power of brief visual distractions. When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color. Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice.","This internal versus external distinction shares some commonality with the literature in judgment and decision making on stated versus revealed preference. Revealed preferences are ""revealed"" by observing actual choice (vs. simply asking consumers to state their preferences). Both types of preferences provide useful information for marketers , but revealed preferences are generally more reliable in predicting future behavior .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/lcrp.12013,Psychology_easy_46,"Close

If you're cramming for a test or have an important date to remember, you might find this simple tip useful: close your eyes.","For questions about visual details, participants who closed their eyes at T2 were significantly more accurate (M = 0.83, SD = 0.16) than participants who kept their eyes open (M = 0.65, SD = 0.20), F(1, 44) = 11.39, p = .002, g 2 = .21.","Close

If you're cramming for a test or have an important date to remember, you might find this simple tip useful: close your eyes. The team found that when the participants closed their eyes, they were able to remember 23 percent more information than the people in the other groups. Having a good relationship with the interviewer also helped people answer more questions about the crime correctly, but if the person closed his or her eyes, the recall was effective regardless of the rapport the person felt with the interviewer.","There was a significant main effect of eye-closure at T2, F(1, 44) = 6.37, p = .02, g 2 = .12, which was qualified by a significant interaction between eye-closure during questioning and modality, F(1, 44) = 4.60, p = .04, g 2 = .09. For questions about visual details, participants who closed their eyes at T2 were significantly more accurate (M = 0.83, SD = 0.16) than participants who kept their eyes open (M = 0.65, SD = 0.20), F(1, 44) = 11.39, p = .002, g 2 = .21. For questions about auditory details, eye-closure had no significant effect on accuracy rate (F < 1).",[1],Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1016/j.jpeds.2017.10.028,Psychology_easy_47,The other evidence-based approach he recommends is taking something positive away.,"Second, participants were all located in the southern US, which may limit generalizability to other regions of the country.","As a father himself, he knows this is difficult to adhere to, but he believes this can happen even in the most difficult situation. The other evidence-based approach he recommends is taking something positive away. All of this is in service of teaching children to be respectful without disrupting the vital positive elements of the caretaker-child relationship.","Future research would benefit by including corroborating reports (eg, by parents) and/or a more comprehensive measure of corporal punishment. Second, participants were all located in the southern US, which may limit generalizability to other regions of the country. This latter concern is tempered by the fact that prevalence of corporal punishment and dating violence in the current population was similar to nationally representative samples.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1186/s13229-018-0246-0,Psychology_easy_48,"In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West.","Shenzhen City: prevalence estimate 21,420 out of 21,553 (participation rate = 99.4%) screening questionnaires were completed and returned to the study team from 45 schools (Fig.","This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research."" In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","Thus, the overall prevalence estimate for autism in Jilin City (total population prevalence) was 108.0 per 10,000 (or 1 in 92) (95% CI 87.0, 135.0). Shenzhen City: prevalence estimate 21,420 out of 21,553 (participation rate = 99.4%) screening questionnaires were completed and returned to the study team from 45 schools (Fig. Of these, 11,878 (55.5%) were boys and 9312 (43.5%) were girls.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38803735334&p=1pl&v=1&x=Olj8Q_8mSR67vcOaC9l--A
10.1177/0141076814565942,Psychology_easy_49,"What's more, ""risk was particularly high for infantile autism before age 5 years.""","Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration.","Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years."" What's more, ""risk was particularly high for infantile autism before age 5 years."" That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces.","The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate. Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration. To the extent outcomes were inaccurately or incompletely recorded in the national health registers, we might have missed some true cases, or wrongly included some irrelevant cases, as outcomes in the cohort.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1001/jamapsychiatry.2018.1941,Psychology_easy_50,"Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""","Given that the strengths of the functional connectivities were significantly associated with the PSQI score (β = 5.459 [95% CI, 3.10-7.95]; P =1.2×10 −4 ) and Depressive Problems score (β = 0.0025 [95% CI, 0.00-0.01]; P =6.4×10 −5 ), we assessed","The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments."" So, whatever it is you're going through, remember you're not alone.","In the same 92 participants, other areas with high correlations (all with r values greater than 0.32 and corresponding P values less than .001) with the depressive problems score included the angular gyrus, anterior cingulate cortex, parahippocampal gyrus, and temporal cortex (eTable 3 in the Supplement). Given that the strengths of the functional connectivities were significantly associated with the PSQI score (β = 5.459 [95% CI, 3.10-7.95]; P =1.2×10 −4 ) and Depressive Problems score (β = 0.0025 [95% CI, 0.00-0.01]; P =6.4×10 −5 ), we assessed The association patterns between functional connectivities and sleep duration were very similar in both the HCP and the Biobank data sets ( Figure 3A) .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1111/cdev.12370,Psychology_easy_53,"""These results show that teens can use self-distancing strategies in much the same way as adults,"" White notes.","Finally, following prior research , we assessed the balance of adaptive versus maladaptive reflection by subtracting reconstrual from recounting such that higher scores reflected the predominance of recounting relative to reconstruing (M = 0.86, SD = 2.36).","Older youth who self-distanced became even less upset than younger adolescents who did so. ""These results show that teens can use self-distancing strategies in much the same way as adults,"" White notes. ""They also suggest that the teen years could be critical in developing this way to regulate emotions.""","Therefore, this item was dropped from further analyses (analyses including this item are provided in Appendix S2) and a reconstrual composite was calculated by averaging the two remaining items (r = .20, p < .01, M = 4.01, SD = 1.55). Finally, following prior research , we assessed the balance of adaptive versus maladaptive reflection by subtracting reconstrual from recounting such that higher scores reflected the predominance of recounting relative to reconstruing (M = 0.86, SD = 2.36). As predicted, adolescents who engaged in greater levels of spontaneous self-distancing experienced less emotional distress when recalling an anger-inducing experience, r = À.43, p < .001.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150415092801.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamapsychiatry.2018.3514,Psychology_easy_55,"Given that about 1 million people die by suicide every year, that's a very encouraging prospect for suicide prevention.""","Therefore, command hallucinations to harm oneself may simply reflect underlying suicidal thoughts (as opposed to inducing de novo suicidal thoughts).","Dr Ian Kelleher, RCSI Psychiatry Research Lecturer and study lead, commented: ""Our research shows that if we can understand and treat the factors associated with these perceptual abnormalities, we could prevent at least a quarter of suicide attempts and deaths. Given that about 1 million people die by suicide every year, that's a very encouraging prospect for suicide prevention."" ""These findings show the need both for clinicians to pay particular attention to patients reporting experience of psychotic experience, and for greater funding for research into recognising a psychosis subtype of suicide,"" added Dr Kelleher.","However, the content of hallucinations, including the presence of command hallucinations to harm oneself, cannot be said to emerge at random; rather, hallucination content reflects factors present in the thought content of the affected individual. Therefore, command hallucinations to harm oneself may simply reflect underlying suicidal thoughts (as opposed to inducing de novo suicidal thoughts). 23 It could also be the case that distress associated with PEs increases the risk of suicidal behavior.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37828547572&p=1pl&v=1&x=0DCeKj2mrndVr_6QSdn9XA
10.1007/s13524-014-0321-x,Psychology_easy_56,"""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","is an exception: they found that first births have a positive effect on parental happiness, but higher order births do not.","There was a 50 percent decrease in happiness during the birth of a second child, followed by a total slump by the time the third child is born. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings. Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources.","Part of the stronger dip may also be due to a larger anticipation effect. is an exception: they found that first births have a positive effect on parental happiness, but higher order births do not. If a birth is a positive life event, the happiness response to having a child may be strongest when the event is first experienced.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1001/jamapsychiatry.2018.1941,Psychology_easy_57,"And with insomnia statistically affecting more women than men, this is especially great news for us.","These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified.","And with insomnia statistically affecting more women than men, this is especially great news for us. Results showed that 162 functional connectivity links in the brain were connected with our ability (or lack of) to get some shut-eye; of these, 39 were also linked to depressive problems a such as low self-esteem, low mood, and a lack of motivation. The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep.","Much smaller associations were found in the reverse direction; that is, the associations of sleep quality with depressive problems mediated by these links were less significant. These findings provides a neural basis for understanding how depression is associated with poor sleep quality, and this in turn has implications for treatment because of the brain areas identified. Areas in which functional connectivity was associated with depressive problems and their effects on sleep quality included the lateral orbitofrontal cortex, precuneus, and angular gyrus.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1007/s40519-017-0414-9,Psychology_easy_58,"According to the researchers, the apparent prevalence of eating disorders seen in musicians ""could be due to their increased levels of perfectionism"", and the findings could help doctors to look for warning signs among a subset of patients.","Regarding general mental health, the DASS-21 showed that depression and stress were severe, anxiety was extremely severe and the perfectionism inventory composite score was 26.53.","According to the researchers, the apparent prevalence of eating disorders seen in musicians ""could be due to their increased levels of perfectionism"", and the findings could help doctors to look for warning signs among a subset of patients. Almost two-thirds of the participants were female, and the average age of the group was around 31 years of age. After analysing the questionnaire data, the researchers revealed almost one-third of the group (32.3%) reported having experienced an eating disorder, a higher proportion than the estimated 1.6 million adults thought to be affected in the UK.","The median BMI was within the normal range. Regarding general mental health, the DASS-21 showed that depression and stress were severe, anxiety was extremely severe and the perfectionism inventory composite score was 26.53. There was no significant difference on the EDE-QGS between musicians who perform different types of music, but music students, professionals, soloists and musicians travelling overseas had a higher percentage of pathological EDE-QGS.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/musicians-have-high-prevalence-of-eating-disorders-study-finds/
10.1111/cdev.12250,Psychology_easy_59,"Unlike their less popular peers, these kids were actively seeking high school fame.","Early adolescents engaging in high levels of pseudomature behavior will continue to be preoccupied with social status in new social venues (i.e., romantic relationships) as development progresses into early adulthood.","The kids who ran their high schools at 13 tended to drink more, get into trouble more, have more sex, and importantly, sought out popularity. Unlike their less popular peers, these kids were actively seeking high school fame. And as the cohort got older, these mature behaviors got a forceful shove into full-blown recklessness.","3. Early adolescents engaging in high levels of pseudomature behavior will continue to be preoccupied with social status in new social venues (i.e., romantic relationships) as development progresses into early adulthood. Early adolescent pseudomature behavior will predict higher levels of future problems with alcohol and substance use and serious deviant behavior, even after accounting for early signs of such behavior.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1016/j.jalz.2018.06.2856,Psychology_easy_60,"Cataracts meanwhile, most commonly caused by ageing, didn't seem to have the same relationship with Alzheimer's.","Discussion: Increased AD risk was found for recent glaucoma diagnoses, established AMD diagnoses, and both recent and established DR. People with certain ophthalmic conditions may have increased AD risk.","Age-related macular degeneration, diabetic retinopathy, and glaucoma were the three eye conditions that showed a strong link with Alzheimer's. Cataracts meanwhile, most commonly caused by ageing, didn't seem to have the same relationship with Alzheimer's. It's possible that this new correlation with eye diseases could give us more insight into the origins of Alzheimer's, perhaps joining up the dots for some of what's happening in the nervous system.","The recent and established hazard ratio were 1.46 (P 5 .01) and 0.87 (P 5 .19) for glaucoma, 1.20 (P 5 .12) and 1.50 (P , .001) for AMD, and 1.50 (P 5 .045) and 1.50 (P 5 .03) for DR. Discussion: Increased AD risk was found for recent glaucoma diagnoses, established AMD diagnoses, and both recent and established DR. People with certain ophthalmic conditions may have increased AD risk. Research regarding AD risk factors may lead to early detection and preventive measures based on better understanding neurodegenerative processes .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1093/jcr/ucw012,Psychology_easy_61,"The study's findings have broader implications beyond advertising, Smith said.",It is a unique process because consumers are not shown ads based solely on broad demographic or psychographic variables; nor are they presented with ads for the same products they have already viewed or clicked on (as is the case with retargeting; .,"""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said. The study's findings have broader implications beyond advertising, Smith said. ""We like to think we are quite certain of who we are, but this study suggests that's not quite the case,"" he said.","Importantly, these effects only hold when the label is plausibly connected to consumers' prior behavior (i.e., when the targeting is at least moderately accurate). It is a unique process because consumers are not shown ads based solely on broad demographic or psychographic variables; nor are they presented with ads for the same products they have already viewed or clicked on (as is the case with retargeting; . This research introduces the notion that behaviorally targeted advertisements act as implied social labels.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1111/cdev.12250,Psychology_easy_62,"""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said.","No moderating effects were found beyond what would be expected by chance, thus indicating that results described below did not reliably differ between males and females or between adolescents from high-versus low-income families.","By 22, the cool kids struggled to make friends. ""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.","Several variables of substantive interest in the study were related to both adolescent gender and income in the adolescent's family of origin; hence, these factors were considered as covariates in the analyses below. No moderating effects were found beyond what would be expected by chance, thus indicating that results described below did not reliably differ between males and females or between adolescents from high-versus low-income families. For descriptive purposes, Table 1 also presents simple correlations among all primary constructs examined in the study.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1093/jcr/ucw012,Psychology_easy_63,"For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad.",Another potential boundary condition that could be fruitfully explored is the degree to which consumers exhibit impression management in their online actions.,"If an ad makes you feel sophisticated or environmentally conscious, you are more likely to engage in all kinds of behaviors related to that trait - not just buy the advertised product,"" Reczek said. For example, in one experiment, participants who received a behaviorally targeted ad for an environmentally friendly product were more likely than others to donate to an environmental cause later because they saw themselves as being more ""green"" as a result of receiving the ad. One key qualification: The information the behaviorally targeted ad conveys about the consumer must be accurate.","For example, source credibility should only moderate the effect of social labels. Another potential boundary condition that could be fruitfully explored is the degree to which consumers exhibit impression management in their online actions. If consumers know in advance that their browsing or shopping choices are being monitored specifically for the delivery of an ad, they might strategically change their behaviors to receive different ads or might be unwilling to accept a label that has been generated from such inauthentic, impressionmanaged behaviors.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/s41598-017-18902-w,Psychology_easy_64,"The study's results, reported in Scientific Reports, suggest a more accurate method to diagnose autism.",Similar accuracy (above 90%) was obtained when we chose 70% of the data as training data with the remaining data as test set (details in Methods).,"The study's results, reported in Scientific Reports, suggest a more accurate method to diagnose autism. ""We've found that every person has their own unique 'movement DNA,'"" says senior author Jorge V. Jose, professor of physics at Indiana University Bloomington. ""The use of movement as a 'biomarker' for autism could represent an important leap forward in detection and treatment of the disorder.""",The data set classification accuracy is 95.45%. Similar accuracy (above 90%) was obtained when we chose 70% of the data as training data with the remaining data as test set (details in Methods). Figure 5C shows a clear separation between immature and mature TD individuals in the R-space.,[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1038/s41598-017-18902-w,Psychology_easy_65,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.",We found an 'a posterior' agreement between the parameter values we determined from the data and a battery of clinical diagnosed neurodevelopment stages carried out by psychiatrists.,"The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism.","The average training set accuracy (in 50 iterations) is 95.73% and the average test set accuracy is 97.86%. We found an 'a posterior' agreement between the parameter values we determined from the data and a battery of clinical diagnosed neurodevelopment stages carried out by psychiatrists. After doing our blind statistical analyses, we found a very close correlation between the psychiatric diagnoses and our results.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1038/nn.3635,Psychology_easy_66,"Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say.",4) .,"The approach will be useful for future studies elucidating other perceptual and cognitive processes,"" says Kriegeskorte, who was not part of the research team. Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say. It could also shed light on processes that underlie conditions such as memory disorders or dyslexia, and could benefit patients suffering from paralysis or neurodegenerative diseases.",The 92 × 92 MEG decoding matrices contained complex high-dimensional structure that was difficult to visualize. 4) . The null hypothesis of no experimental effect differed throughout the paper depending on the analysis of interest: the MEG decoding time series was equal to 50% chance level; the within-subdivision minus between-subdivision portions of an MEG decoding matrix was equal to 0; the correlation of the MEG decoding matrices and fMRI (or monkey spiking activity) dissimilarity matrix was equal to 0.,[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/chemse/bjt066,Psychology_easy_67,"Conversely, the same odours were considered unpleasant and inedible when associated with negative labels - even the food odours.","Further, geraniol was the only odor that was rated as pleasant when its ratings for positive and negative labels were collapsed together (although its negative label was neutral).","Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels. Conversely, the same odours were considered unpleasant and inedible when associated with negative labels - even the food odours. ""It shows that odour perception is not objective: it is affected by the cognitive interpretation that occurs when one looks at a label,"" says Manescu.","A possible explanation for this effect could be that the label ""cheap perfume"" is not truly negative or that it is less negative compared with other negative labels in the present study. Further, geraniol was the only odor that was rated as pleasant when its ratings for positive and negative labels were collapsed together (although its negative label was neutral). It is conceivable that the effect of labels on perceived intensity is less prominent for pleasant odors.",[1],Psychology,train,1.0,news,http://www.healthcanal.com/eyes-vision/47601-smelling-with-our-eyes-descriptions-affect-odour-perception.html
10.1111/lcrp.12013,Psychology_easy_70,"""It is clear from our research that closing the eyes and building rapport help with witness recall.",Table 2 shows cued-recall performance.,"However, participants who had built a rapport said that they felt more comfortable when they closed their eyes. ""It is clear from our research that closing the eyes and building rapport help with witness recall. Although closing your eyes to remember seems to work whether or not rapport has been built beforehand, our results show that building rapport makes witnesses more at ease with closing their eyes.","Separate two-way ANOVAs on the number of visual and auditory incorrect new details, respectively, revealed no significant effects either (all Fs < 2.77; all ps > .10). Table 2 shows cued-recall performance. Eye-closure at T1 did not have a significant effect on cued-recall performance a week later, F(1, 44) = 2.62, p = .11, g 2 = .05.",[1],Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1186/2045-5380-3-19,Psychology_easy_71,"The overall effect is to bring the brain down from a state of over-stimulation to a normal, baseline stimulation level.","Only time, and clinical trials, will tell if this system truly represents a novel therapeutic target for mood and anxiety disorders.","This, in turn, helps improve focus and attention in those with ADHD. The overall effect is to bring the brain down from a state of over-stimulation to a normal, baseline stimulation level. It also has a high potential for abuse and misuse.","As such, the eCB system represents an ideal system for translational research since human studies generally corroborate animal studies. Animal studies can delve further into the mechanism and inform future clinical studies investigating the role of eCB signaling in treating psychiatric disorders. Only time, and clinical trials, will tell if this system truly represents a novel therapeutic target for mood and anxiety disorders.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1093/jcr/ucw012,Psychology_easy_74,"""In this case, receiving a behaviorally targeted ad from a restaurant suggesting that you are a 'sophisticated' food consumer makes you think, 'I may be more sophisticated than I thought.'","noting that ""a category label becomes an identity once the consumer has begun to incorporate it into his or her sense of who he or she is and has initiated the process to become that kind of person"" (2012, 312) .","They were also more likely to say they would purchase the Groupon than those in the other two groups. ""In this case, receiving a behaviorally targeted ad from a restaurant suggesting that you are a 'sophisticated' food consumer makes you think, 'I may be more sophisticated than I thought.' That in turn makes you more likely to buy a Groupon for the restaurant.""","It is important to distinguish between the nature and the effects of an implied social label and the activation of an element of a consumer's identity. noting that ""a category label becomes an identity once the consumer has begun to incorporate it into his or her sense of who he or she is and has initiated the process to become that kind of person"" (2012, 312) . Advertisements can prime identities, such as when an ad featuring an image of the Great Wall of China makes a Chinese consumer's Chinese identity more salient .",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1016/j.jarmac.2014.03.005,Psychology_easy_75,"Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs.","For instance, in a standard two-alternative forced-choice recognition test (e.g., ; four of the 40 Original Memory effect sizes came from such tests), de-biasing may be entirely sufficient to restore original memory performance, as discrediting the misleading detail automatically favours reporting the original detail.","This meant that voters were relatively well informed about both sides. Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs. Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign.","The relative contributions probably depend on specific aspects of the studies, for instance on the type of memory test used. For instance, in a standard two-alternative forced-choice recognition test (e.g., ; four of the 40 Original Memory effect sizes came from such tests), de-biasing may be entirely sufficient to restore original memory performance, as discrediting the misleading detail automatically favours reporting the original detail. By contrast, in recall tests (accounting for ~ 40% of the Original Memory effect sizes) de-biasing in itself may not help very much unless access to -or discrimination of -original event details is otherwise facilitated or restored.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1038/nn.3635,Psychology_easy_78,"Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say.","In the meantime, the linkage between the time course of individual object coding in humans and coding of these same objects in monkey IT, although predictable by previous research, is shown here to our knowledge for the first time.","The approach will be useful for future studies elucidating other perceptual and cognitive processes,"" says Kriegeskorte, who was not part of the research team. Using this approach, scientists should also be able to study how the human brain analyzes other types of information such as motor, verbal, or sensory signals, the researchers say. It could also shed light on processes that underlie conditions such as memory disorders or dyslexia, and could benefit patients suffering from paralysis or neurodegenerative diseases.","Future studies might compare the dynamics in human and monkey IT using monkey data resolved in time, thus potentially complementing spatial homologies with temporal ones. In the meantime, the linkage between the time course of individual object coding in humans and coding of these same objects in monkey IT, although predictable by previous research, is shown here to our knowledge for the first time. Progress in understanding how object recognition is implemented in the brain is likely to come from the combination of advances in data analyses suitable for different imaging techniques and comparison npg a r t I C l e S across species .",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_easy_79,One thing to note is that this was a relatively small study.,"However, over the following years, pseudomature behavior was associated with a significant relative decline in levels of popularity.","Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study. One thing to note is that this was a relatively small study. Though participants were from both urban and suburban areas, 184 kids can't be enough to be totally sure about widespread patterns.","Results, presented in Table 2 , based on a highly significant overall linear growth model, v 2 (3) = 249.5, p < .001, indicate that pseudomature behavior was associated with higher levels of popularity among peers at age 13, as predicted. However, over the following years, pseudomature behavior was associated with a significant relative decline in levels of popularity. This indicates that, as hypothesized, pseudomature behavior was indeed linked to higher status with peers early in adolescence, but that as development progresses and peers mature, this link steadily fades out, and was no longer present by age 15 (see Figure 1) .",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1093/jcr/ucw012,Psychology_easy_80,"While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them.",Study 2 sheds light on this process by measuring consumers' self-perceptions.,"""The ad has to be plausible to the consumer for it have any effect,"" Reczek said. While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them. ""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said.","The data also show that the effects of behavioral targeting are not due to differences in liking for the advertisement because consumers liked the ad equally in all conditions. Study 2 sheds light on this process by measuring consumers' self-perceptions. Second, we increase the external validity of our work by manipulating awareness of whether the ad is behaviorally targeted using the industry-standard AdChoices icon.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1038/s41598-018-30980-y,Psychology_easy_81,"Naps do contribute to emotion processing at this young age.""","Finally, we failed to replicate the original findings of Kinzler and Shutts 18 in which memory for negative stimuli was greater than memory for positive stimuli immediately after encoding.","""Our results are consistent with these observations of caregivers. Naps do contribute to emotion processing at this young age."" To do this, they presented children ages approximately three to five years (34-64 months) with faces paired with mean or nice word descriptions, but they saw no significant main effects of emotional valence on recognition memory.","Nevertheless, we feel that these results indicate a need for further research into emotional memory consolidation across a nap and subsequent overnight sleep in preschool-aged chidren. Finally, we failed to replicate the original findings of Kinzler and Shutts 18 in which memory for negative stimuli was greater than memory for positive stimuli immediately after encoding. While on average the Kinzler and Shutts study demonstrated a negativity bias in emotional recognition memory, they did however report large individual differences in emotional bias (differences in accuracy of recognizing positive or negative stimuli).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1038/s41598-018-30980-y,Psychology_easy_82,"""This study demonstrates that napping is beneficial to memory processing,"" they point out.","However, emotional memories are unique in the neural basis of encoding as well as the sleep physiology underlying consolidation.","As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits."" ""This study demonstrates that napping is beneficial to memory processing,"" they point out. ""Given the importance of socio-emotional learning in preschool naps averaging 70 minutes may support the curricular goals of early childhood education.","Naps in early childhood support declarative memory consolidation. However, emotional memories are unique in the neural basis of encoding as well as the sleep physiology underlying consolidation. There were no significant main effects of emotional valence on recognition memory.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1136/bmjsem-2017-000261,Psychology_easy_83,"They found that there was a asignificant anticipatory cortisol response before competition,a although the spikes werenat as strong as those seen before other intense events, like skydiving.",This shared responsibility to the outcome and opportunities for social interaction reduces cognitive and somatic anxiety responses before sport competition in team sport athletes in comparison to individual athletes.,"A spike in cortisol in athletesa saliva before competition, they wrote, would support the idea that apsychosocial stressorsa can have as strong a biological effect as actual danger. They found that there was a asignificant anticipatory cortisol response before competition,a although the spikes werenat as strong as those seen before other intense events, like skydiving. Also, notably, they only noticed statistically significant spikes in the saliva cortisol levels of male athletes, which the authors admit requires further investigation.","This cooperation offers opportunities for social interactions between athletes in preparation to and during competition. This shared responsibility to the outcome and opportunities for social interaction reduces cognitive and somatic anxiety responses before sport competition in team sport athletes in comparison to individual athletes. 7 43 In addition, providing verbal social support during psychosocial stress tasks reduces the cortisol response in comparison to not receiving this support.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34474732617&p=1pl&v=1&x=pcdQFFmMveKF7UrJyJtzvg
10.1038/s41598-017-18902-w,Psychology_easy_84,The new motion data strengthens evidence for movement as a biomarker for autism.,We will show below that it has an extraordinary individualized classification power in neurodevelopment.,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism. Next, the researchers aim to conduct movement assessments on more people, including more research on the parents of children with autism to better understand the connection between lower parental scores on the movement assessment and their children's risk for autism.","This shows that the R-parameter very well characterizes the simulated speed profile's SNR, i.e. We will show below that it has an extraordinary individualized classification power in neurodevelopment. The R-parameter differentiates ASD and mature TD.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1186/2045-5380-3-19,Psychology_easy_85,"It can help with focus, and concentration in the same way as Adderall.","For example, repeated treatment of mice with the MAGL inhibitor JZL-184, which increases brain 2-AG levels, prevents repeated restraint stress-induced anxiety measured in the novelty-induced hypophagia assay .","Of course, CBD is more than an Adderall alternative. It can help with focus, and concentration in the same way as Adderall. But, it also has a wide range of other health benefits and uses.","Based on the totality of data reviewed this far, strong evidence points to eCB signaling as a stress-buffering system, and that one contribution to behavioral dysregulation induced by stress is an AEA-deficient state. For example, repeated treatment of mice with the MAGL inhibitor JZL-184, which increases brain 2-AG levels, prevents repeated restraint stress-induced anxiety measured in the novelty-induced hypophagia assay . Furthermore, both pharmacological and genetic inhibition of FAAH prevents chronic restraint stress-induced anxiety in the elevated plus-maze , as well as CUS-induced anhedonia .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1111/cdep.12038,Psychology_easy_86,"Of the countries included in the study, 30 have passed laws fully banning physical punishment of children, both in schools and in homes.",We thus have research-based and humanrights-based reasons for not spanking our children.,"And, says Frank Elgar, the study's lead author and an associate professor at the Institute for Health and Social Policy at McGill University in Montreal, ""The association appears to be fairly robust."" Of the countries included in the study, 30 have passed laws fully banning physical punishment of children, both in schools and in homes. The rates of fighting among adolescents were substantially lower than the 20 countries with no bans in place: by 69 percent for adolescent males and 42 less for females.","We now have enough research to conclude that spanking is ineffective at best and harmful to children at worst. We thus have research-based and humanrights-based reasons for not spanking our children. But there is a third reason not to spank our children, and that is a moral one.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37496755330&p=1pl&v=1&x=D2_ff5Et7h_ldttAmZUuVw
10.1038/s41598-018-30980-y,Psychology_easy_87,"Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude.","However, emotional memories are unique in the neural basis of encoding as well as the sleep physiology underlying consolidation.","Yet nap slow wave activity also predicted greater overnight improvement in memory. Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude. Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children.""","Naps in early childhood support declarative memory consolidation. However, emotional memories are unique in the neural basis of encoding as well as the sleep physiology underlying consolidation. There were no significant main effects of emotional valence on recognition memory.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1016/j.jarmac.2014.03.005,Psychology_easy_88,"""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude.","using post-warning vs. nowarning as a moderator) returned a highly significant moderator effect for both Original Memory, Q(1) 6 = 20.96, p < .001, and Misinformation Endorsement, Q(1) = 27.40, p < .001.","Devising strategies to prevent false voter memories may require implementing more sophisticated measures, perhaps in addition to issuing warnings about misinformation. ""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events.","better misled than control performance). using post-warning vs. nowarning as a moderator) returned a highly significant moderator effect for both Original Memory, Q(1) 6 = 20.96, p < .001, and Misinformation Endorsement, Q(1) = 27.40, p < .001. taking sample size into account; see As with most moderator analyses, one limitation of the preceding analyses is that they are essentially [82]",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1080/08870446.2013.818674,Psychology_easy_90,Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good.,"At Tl , the average number of daily smoked cigarettes was 16.59 (SD=8.52, range 1-40) and at T2 on average 5.27 (SD=6.97, range 0-40), showing a significant reduction from T1 to T2 (F(l, 97)=195.67, p=.001).","Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette). Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good. When occurring on their own, self-efficacy, coping strategies and social support did not increase the chances of quitting.","This technique provides the range of the moderator within which the simple slope of the dependent variable on the predictor is significantly different from zero . At Tl , the average number of daily smoked cigarettes was 16.59 (SD=8.52, range 1-40) and at T2 on average 5.27 (SD=6.97, range 0-40), showing a significant reduction from T1 to T2 (F(l, 97)=195.67, p=.001). According to the measure of continuous abstinence, 34 (3 2.1%) participants did not smoke between their quit date and T2.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1111/lcrp.12013,Psychology_easy_91,"That in itself is vital if we are to encourage witnesses to use this helpful technique during interviews,"" said Dr. Robert Nash, lead author of the study.","This main effect was qualified by a significant interaction between eye-closure during questioning and modality of encoded information, F(1, 44) = 7.24, p = .01, g 2 = .07.","Although closing your eyes to remember seems to work whether or not rapport has been built beforehand, our results show that building rapport makes witnesses more at ease with closing their eyes. That in itself is vital if we are to encourage witnesses to use this helpful technique during interviews,"" said Dr. Robert Nash, lead author of the study. Can this revelation help people remember other types of information in other circumstances?","Participants who closed their eyes during the second session, however, answered significantly more questions correctly (M = 9.21, SD = 1.93) than participants who kept their eyes open (M = 7.67, SD = 2.20), F(1, 44) = 6.77, p = .01, g 2 = .13. This main effect was qualified by a significant interaction between eye-closure during questioning and modality of encoded information, F(1, 44) = 7.24, p = .01, g 2 = .07. Simple effects analyses showed that eye-closure at T2 increased correct recall of visual details by 35.3% (from 4.38 to 5.92), F(1, 44) = 10.06, p = .003, g 2 = .19, but did not affect correct recall of auditory details (F < 1).",[1],Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1007/s13524-014-0321-x,Psychology_easy_93,The researchers also discovered that having a baby at older age is more beneficial psychologically.,"Women also have steeper drops between the year of the birth and the year afterward, possibly because of a larger initial gain.","Sociologists Mikko Myrskyla and Rachel Margolis found out that third child does not make subjective well-being greater. The researchers also discovered that having a baby at older age is more beneficial psychologically. Although many different explanations of this phenomenon were proposed, relatively little attention was paid to subjective well-being of parents.","In both Britain and Germany, women gain more in happiness in expectation (differences statistically significant in both data sets with p < .10) and right after the birth of a child (p < .05 in both data sets). Women also have steeper drops between the year of the birth and the year afterward, possibly because of a larger initial gain. In the long-run, there are no differences between men and women.",[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1176/appi.ajp.2018.17111282,Psychology_easy_94,"The 23andMe test will tell consumers about 33 genetic variants that are associated with how well common drugs -- blood thinners like Plavix and Coumadin, for example -- work, but it's explicit that consumers should not change their medications based on these results.","Of the eight health care utilization measures assessed, several did not attain statistical significance, including inpatient visits.","The manufacturer, 23andMe, won FDA approval by being very careful not to overpromise what its test can do-- so careful that the approval highlights the limited usefulness of the test and how much we still don't know about this field of medicine. The 23andMe test will tell consumers about 33 genetic variants that are associated with how well common drugs -- blood thinners like Plavix and Coumadin, for example -- work, but it's explicit that consumers should not change their medications based on these results. The test is only supposed to provide some potentially useful information that people can discuss with their doctor.","In a 1-year, blinded, retrospective study, the number of outpatient health care visits, number of medical absence days, and number of disability claims were found to be significantly greater (p=0.015, p=0.04, and p=0.003, respectively) among patients treated with genotype-discordant medications (N=9; red bin) as compared with patients treated with genotype-concordant medications (N=39; green bin), equating to a total yearly savings of $5,174 . Of the eight health care utilization measures assessed, several did not attain statistical significance, including inpatient visits. Inclusion of patients with anxiety disorders and lack of a treatment-as-usual group were notable limitations.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1093/jcr/ucw012,Psychology_easy_95,"Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner.","Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition).","While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals. Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner. ""If people don't see the trait implied by an ad as negative, our research suggests that they would see themselves as having the trait to a greater extent,"" she says.","The results from study 1 provide support for the hypothesis that behaviorally targeted advertisements can act as implied social labels, resulting in adjustments to behavior consistent with the label. Consumers in the behaviorally targeted and the demographically targeted condition felt equally that the ad was matched to personal information from earlier in the experimental session (to a significantly greater extent than participants in the control, nontargeted condition). However, participants in the behaviorally targeted condition recognized a label from the marketer as a result of this individual-level information matching to a greater extent than participants in the demographic targeting and nontargeting condition and demonstrated higher willingness to purchase the advertised product because of its consistency with this implied identity.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1186/2045-5380-3-19,Psychology_easy_96,"Using CBD, therefore, reduces the need for stimulants like Adderall.","Thus, consistent with data obtained from animal studies, these data support the possibility that impaired eCB activity could be a predisposing factor for the development of stress-related neuropsychiatric conditions.","As a result, CBD helps restore balance, reducing the negative symptoms that ADHD sufferers experience, while also improving concentration. Using CBD, therefore, reduces the need for stimulants like Adderall. And, unlike Adderall, CBD also helps ADHD sufferers deal with other mental health issues, such as anxiety disorders.","Accordingly, these pharmacological studies in humans demonstrate that disruption of eCB signaling is sufficient to promote anxiety, increase HPA axis activity, impair reward processes in the brain and enhance negative emotional memory biases, all of which are all hallmark signs of mood disorders. Thus, consistent with data obtained from animal studies, these data support the possibility that impaired eCB activity could be a predisposing factor for the development of stress-related neuropsychiatric conditions. Again, as was seen in the pharmacological studies in humans, the data generated to date are largely consistent with what has been found in preclinical studies.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1016/j.jarmac.2014.03.005,Psychology_easy_98,"The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created.","For instance, with respect to warning specificity, one should expect warnings that mention only the possibility of misinformation, rather than positively assert its presence, to be less effective.","""High cognitive ability may allow individuals to overcome the biasing effect of political orientation and more effectively monitor the sources of their memories,"" the authors note. The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created. Devising strategies to prevent false voter memories may require implementing more sophisticated measures, perhaps in addition to issuing warnings about misinformation.","Some of the moderators seem to make theoretical sense. For instance, with respect to warning specificity, one should expect warnings that mention only the possibility of misinformation, rather than positively assert its presence, to be less effective. Descriptively, this was indeed so (when outlying effect sizes were excluded), but the moderator effect did not reach significance.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1016/j.jpeds.2017.10.028,Psychology_easy_99,"When you're not consistent with your consequences, it makes it less likely that the child will change his or her behavior.","There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) .","Whatever consequence you identify must be enforced every time. When you're not consistent with your consequences, it makes it less likely that the child will change his or her behavior. Reward your child with attention.","Nineteen percent of participants (n = 134) reported physical perpetration of dating violence, and more than one-half (68%) reported experiencing corporal punishment as children (n = 498, mean = 1.07, SD = 0.96). There was no significant association by sex (c 2 [3] = 3.52, P = .32), ethnicity (c 2 = 15.86, P =.07), or parental education (c 2 = 9.38, P = .40) differences in terms of corporal punishment (Table II) . More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32818256385&p=1pl&v=1&x=0ZAEkx105k29I5f3n6_nlQ
10.1177/0963662516629749,Psychology_easy_100,"and the mind-boggling behaviours of birds (such as the manakins shown doing a shuffle dance), Our Planet will engage a whole new generation.","In an era where science is becoming increasingly contentious politically, curriculum reform that is designed to produce a more educated citizenry represents an area of common ground for virtually all actors in the policy making process.","So many of us working in conservation were drawn in through watching Sir David Attenborough's other films as children. and the mind-boggling behaviours of birds (such as the manakins shown doing a shuffle dance), Our Planet will engage a whole new generation. However feeling connected with nature does matter.","While it would be naïve to suggest that curriculum reform is a simple process, an approach to the lagging levels of public support for science that focuses on education enjoys at least one key advantage; it promises to be a largely bipartisan effort, at least relative to other approaches that might target values or employ persuasive messaging. In an era where science is becoming increasingly contentious politically, curriculum reform that is designed to produce a more educated citizenry represents an area of common ground for virtually all actors in the policy making process. debates over teaching evolution), Republicans and Democrats, the rich and the poor, scientists and lay audiences all understand the need for a scientifically literate and informed citizenry.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.1177/0141076814565942,Psychology_easy_104,"What's more, ""risk was particularly high for infantile autism before age 5 years.""","showed that even the youngest infants had full capacity for conscious perception, although their ability to express such perceptions had not yet developed.","Regardless of background, the team explains, ""circumcised boys were more likely than intact boys to develop ASD before age 10 years."" What's more, ""risk was particularly high for infantile autism before age 5 years."" That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces.","Psychological problems were encountered in 4% of children aged < years at the time of operation, as compared with 0% among older children. showed that even the youngest infants had full capacity for conscious perception, although their ability to express such perceptions had not yet developed. , , 4 Regardless of surgical method, circumcision causes some level of pain and discomfort at the operation table and for several days after until wound healing has completed.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1093/chemse/bjt066,Psychology_easy_105,"""It shows that odour perception is not objective: it is affected by the cognitive interpretation that occurs when one looks at a label,"" says Manescu.","Its positive label yielded faster reaction times than the negative label, which is contrary to our expectations.","Conversely, the same odours were considered unpleasant and inedible when associated with negative labels -- even the food odours. ""It shows that odour perception is not objective: it is affected by the cognitive interpretation that occurs when one looks at a label,"" says Manescu. ""Moreover, this is the first time we have been able to influence the edibility perception of an odour, even though the positive and negative labels accompanying the odours showed non-food words,"" adds Frasnelli.","Although we observed a significant main effect of label, post hoc tests revealed an effect only for one of the odorants, parmesan cheese. Its positive label yielded faster reaction times than the negative label, which is contrary to our expectations. We consider several options to explain this effect.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamapsychiatry.2018.1941,Psychology_easy_108,"The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep.","Of these links, 39 were also associated with the Depressive Problems scores.","The researchers found functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions, which cause sufferers to dwell on bad thoughts and lead to a poor quality of sleep. This research could lead to better sleep quality for people with depression, and opens up the possibility of new targeted treatments. In the brains of those living with depressive problems, they discovered a strong connection between the dorsolateral prefrontal cortex (associated with short-term memory), the precuneus (associated with the self), and the lateral orbitofrontal cortex (associated with negative emotion).","A total of 162 functional connectivity links involving areas associated with sleep, such as the precuneus, anterior cingulate cortex, and the lateral orbitofrontal cortex, were identified. Of these links, 39 were also associated with the Depressive Problems scores. The brain areas with increased functional connectivity associated with both sleep and Depressive Problems scores included the lateral orbitofrontal cortex, dorsolateral prefrontal cortex, anterior and posterior cingulate cortices, insula, parahippocampal gyrus, hippocampus, amygdala, temporal cortex, and precuneus.",[1],Psychology,train,1.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1001/jamapsychiatry.2018.1941,Psychology_easy_110,"Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain.","Although participants of the HCP data set were not selected to have a psychiatric disorder and most are healthy control participants, the Depressive Problems raw score was a useful indicator of depression, in that 92 participants who reported having been diagnosed with a major depressive episode also had significantly higher scores on this measure.","They found that thereas functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions. Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans.","We note that only 2 of the 123 items in the Adult Self Report questionnaire, which are used to calculate the Depressive Problems Score, are on the topic of sleep quality, and so these are unlikely to account for the correlations in this study. Although participants of the HCP data set were not selected to have a psychiatric disorder and most are healthy control participants, the Depressive Problems raw score was a useful indicator of depression, in that 92 participants who reported having been diagnosed with a major depressive episode also had significantly higher scores on this measure. This data set included 8718 participants.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1093/chemse/bjt066,Psychology_easy_111,"""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.",People react faster to food odors compared with nonfood odors ).,"""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin -- which was rated positively when presented with the label ""Indian food"" -- did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","However, edibility of the odorant could better explain our results. People react faster to food odors compared with nonfood odors ). This may explain why the positive label elicited a significantly faster reaction time than the negative one, as the latter was not associated with food.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdep.12038,Psychology_easy_114,"""No school can be considered safe or supportive if its students are fearful of being physically punished.""","But there is a third reason not to spank our children, and that is a moral one.","""No school can be considered safe or supportive if its students are fearful of being physically punished."" She also noted that this practice should no longer be a part of American childrearing. The study found that spanking was associated with an increase in mental health problems in childhood and adulthood.","We thus have research-based and humanrights-based reasons for not spanking our children. But there is a third reason not to spank our children, and that is a moral one. By using the euphemistic term spanking, parents feel justified in hitting their children while not acknowledging that they are, in fact, hitting.",[1],Psychology,train,1.0,news,http://www.universityherald.com/articles/51514/20161124/education-secretary-schools-stop-use-corporal-punishment.htm
10.1111/cdev.12250,Psychology_easy_115,"By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset.","Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence.","But over the course of the next two years, from the time they were age 13 to when they turned 15, these ""cool"" kids' social status drastically declined, as shown in the graph below: Allen et al. By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","5. Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence. Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1073/pnas.1702671114,Psychology_easy_117,"When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization.","For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured.","""...the speed at which an echolocating bat responds to ambient noise is truly shocking: 10 times faster than we blink our eyes."" When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization. Even in terms of near-instantaneous brain reactions, they call this reflex ""remarkably short.""","First, the duration of the vocalizations under investigation sets the finest latency measurement resolution. For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured. For example, using the data from the 500-ms continuous noise experiment (experiment 1) we estimated the response latency for the Lombard effect to be between 25 and 75 ms because calls were 2.2 ± 0.7 dB more intense for the 75-ms call group statistically, but not for the 25-ms call group.",[1],Psychology,train,1.0,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1176/appi.ajp.2018.17111282,Psychology_easy_118,"Even though 23andMe has been more successful than other companies in gaining FDA approval, that doesn't mean its test is useful or necessary.","With over 30 combinatorial pharmacogenetic tools on the market, evaluating the relative clinical value of each variant independently is not practical, and such an approach does not test the proprietary algorithmbased phenotyping that is unique to each combinatorial pharmacogenetic product.","The tests they researched also didn't agree on what medical recommendations to make when they detected that a patient had a particular gene variant. Even though 23andMe has been more successful than other companies in gaining FDA approval, that doesn't mean its test is useful or necessary. It's simply too early.","Furthermore, evaluating the level of evidence for each variant is a painstaking process, even with access to resources such as the PharmGKB knowledge base. With over 30 combinatorial pharmacogenetic tools on the market, evaluating the relative clinical value of each variant independently is not practical, and such an approach does not test the proprietary algorithmbased phenotyping that is unique to each combinatorial pharmacogenetic product. Although substantial ambiguity remains as to which are the most relevant candidates for further development , we can envision a day when even more comprehensive combinatorial pharmacogenetic tests and more elaborate algorithms are available to predict antidepressant efficacy and tolerability for any patient.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1073/pnas.1505114112,Psychology_easy_120,"""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" says Nina Kraus, senior study author and director of the Auditory Neuroscience Laboratory at Northwestern University.",A feature common to both music and JROTC training is synchronization to perceptual cues.,"The gains were seen during group music classes included in the schools' curriculum, suggesting in-school training accelerates neurodevelopment. ""While music programs are often the first to be cut when the school budget is tight, these results highlight music's place in the high school curriculum,"" says Nina Kraus, senior study author and director of the Auditory Neuroscience Laboratory at Northwestern University. ""Although learning to play music does not teach skills that seem directly relevant to most careers, the results suggest that music may engender what educators refer to as 'learning to learn.'""","Thus, these seemingly different types of training may share a common characteristic capable of bolstering certain phonological skills. A feature common to both music and JROTC training is synchronization to perceptual cues. Given that both music training and JROTC training enhance phonological awareness and involve synchronization with perceptual cues, future work comparing music training to a passive control group could reveal a divergence not reported here.",[1],Psychology,train,1.0,news,http://www.futurity.org/band-teenagers-brains-965992/
10.1016/j.jpeds.2017.10.028,Psychology_easy_121,He is fundamentally opposed to telling people what not to do.,"Given that parents provide a salient model for how adolescents and young adults behave in intimate relationships, corporal punishment may set the groundwork that physical force is an acceptable means of resolving Highest parental education was created based on either one of participant parents' highest education.",This abdication of the moral high ground is principled. He is fundamentally opposed to telling people what not to do. It's not just a Texas thing; it's proven not to work.,"Social modeling may be particularly toxic when the child admires the perpetrator, and perceives the individual as competent and of high social status. Given that parents provide a salient model for how adolescents and young adults behave in intimate relationships, corporal punishment may set the groundwork that physical force is an acceptable means of resolving Highest parental education was created based on either one of participant parents' highest education. Due to item missingness, the sample sizes for sex, ethnicity, and highest parental education may not match.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1111/cdev.12370,Psychology_easy_123,They were also less likely to continue to blame the other person involved in the event (though not less likely to forgive him or her).,"Continued maturation of the prefrontal cortex, an area critical to self-regulation (e.g., Casey et al., 2010; , as well as practice using these strategies ) could contribute to increased efficacy of spontaneous self-distancing across adolescence.","These youth were more likely to reconsider the events in meaningful and insightful ways, and less likely to simply replay the upsetting events in their minds. They were also less likely to continue to blame the other person involved in the event (though not less likely to forgive him or her). In turn, these new insights were associated with less emotional distress.","If self-distancing follows a similar developmental trajectory to other regulatory strategies, such as distraction or reappraisal, its use should increase from childhood through adolescence . Continued maturation of the prefrontal cortex, an area critical to self-regulation (e.g., Casey et al., 2010; , as well as practice using these strategies ) could contribute to increased efficacy of spontaneous self-distancing across adolescence. Together, these data suggest that spontaneous self-distancing could be widely implemented across adolescence, but that its efficacy might increase with age.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150415092801.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.jpeds.2017.10.028,Psychology_easy_125,"She doesn't do that kind of stuff as often,"" she said.","Future research would benefit by including corroborating reports (eg, by parents) and/or a more comprehensive measure of corporal punishment.","She doesn't do that kind of stuff as often,"" she said. Reaction online was mixed--some people agreed with Kelly, while others were horrified:

@kelly_clarkson spanking is disgusting, unacceptable and is a basically a form of physical violence and is abuse. You may have turned out ""fine"".","Thus, it is possible that participants may have, on the one hand, opted for more socially desirable responses, or on the other, inflated or misremembered actual events. Future research would benefit by including corroborating reports (eg, by parents) and/or a more comprehensive measure of corporal punishment. Second, participants were all located in the southern US, which may limit generalizability to other regions of the country.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33001285672&p=1pl&v=1&x=mY8JhuBWW01QmuVJVuzYBw
10.1038/s41598-017-18902-w,Psychology_easy_127,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","This shows that the R-parameter very well characterizes the simulated speed profile's SNR, i.e.","The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism.","Of importance is that we have normalized R to be independent of the actual number of trials included in the experiments. This shows that the R-parameter very well characterizes the simulated speed profile's SNR, i.e. We will show below that it has an extraordinary individualized classification power in neurodevelopment.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1111/cdev.12370,Psychology_easy_128,"In turn, these new insights were associated with less emotional distress.","Therefore, this item was dropped from further analyses (analyses including this item are provided in Appendix S2) and a reconstrual composite was calculated by averaging the two remaining items (r = .20, p < .01, M = 4.01, SD = 1.55).","They were also less likely to continue to blame the other person involved in the event, though not less likely to forgive him or her. In turn, these new insights were associated with less emotional distress. ""In fact, they were dealing with them in a more adaptive way.""","Post hoc inspection of adolescents' ratings on the third reconstrual item, regarding understanding, revealed that it was unexpectedly related to greater emotional reactivity (r = .19, p < .01), a pattern opposite to the first two reconstrual items (rs = À.06 and À.09, respectively) as well as previous research (e.g., . Therefore, this item was dropped from further analyses (analyses including this item are provided in Appendix S2) and a reconstrual composite was calculated by averaging the two remaining items (r = .20, p < .01, M = 4.01, SD = 1.55). Finally, following prior research , we assessed the balance of adaptive versus maladaptive reflection by subtracting reconstrual from recounting such that higher scores reflected the predominance of recounting relative to reconstruing (M = 0.86, SD = 2.36).",[1],Psychology,train,1.0,news,http://www.futurity.org/teens-emotions-distance-903192/
10.1038/s41598-017-18902-w,Psychology_easy_129,The volunteers who scored lower on the scale also exhibited more severe forms of autism.,"If R = 0, all the s-IPIs are distributed exponentially, suggesting total randomness in the s-Peaks' appearances.","In each case, the movement-based diagnoses corresponded to these qualitative-based assessments, which are rarely in complete agreement. The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","3I , the non-exponential contributions in the s-IPIs distributions represent the systematic differences across different If R = 0, all the s-IPIs are distributed exponentially, suggesting total randomness in the s-Peaks' appearances. R increases as the non-exponential contributions increase.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1073/pnas.1702671114,Psychology_easy_131,It could also help point the way to assistive medical devices.,"For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured.","The new information may lead to better understanding of and treatment for diseases, such as Parkinson's, where the Lombard effect may be amplified, researchers say. It could also help point the way to assistive medical devices. Unlike humans, whose vocalizations are comparatively long and slow, bats are ideal for such a sensorimotor study.","First, the duration of the vocalizations under investigation sets the finest latency measurement resolution. For the human and bird experiments ( , the vocalizations studied were about 150 ms long, which constrains the lower latency limit of the Lombard effect that can be measured. For example, using the data from the 500-ms continuous noise experiment (experiment 1) we estimated the response latency for the Lombard effect to be between 25 and 75 ms because calls were 2.2 ± 0.7 dB more intense for the 75-ms call group statistically, but not for the 25-ms call group.",[1],Psychology,train,1.0,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1073/pnas.1505114112,Psychology_easy_132,"It found that those who learned music experienced faster maturation in the brain's response to sound, and heightened sensitivity to details in sound.","Given that both music training and JROTC training enhance phonological awareness and involve synchronization with perceptual cues, future work comparing music training to a passive control group could reveal a divergence not reported here.","It's for these reasons that musical training improves teens' development. It found that those who learned music experienced faster maturation in the brain's response to sound, and heightened sensitivity to details in sound. While all students showed improvement in language skills necessary for reading, it was those who underwent musical training that performed the best three years later.","A feature common to both music and JROTC training is synchronization to perceptual cues. Given that both music training and JROTC training enhance phonological awareness and involve synchronization with perceptual cues, future work comparing music training to a passive control group could reveal a divergence not reported here. On the other hand, we found no gains in rapid naming or phonological memory, despite the fact that both reading and verbal memory have been associated with music training in other studies, suggesting either that the training studied here was not optimally designed to enhance these skills or that enhancing these skills requires a greater amount of training or training begun earlier in life.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1038/s41598-017-18902-w,Psychology_easy_133,"""We really need to narrow the gap between what physicians observe in patients in the clinic and what we're learning about movement within the field of neuroscience.""","The speed profile of the latter case is smoother, having the s-Peaks less random.","The assessments are also difficult to administer to very young children, or to people with impairments such as lack of verbal skills, potentially preventing early interventions for these groups. ""We really need to narrow the gap between what physicians observe in patients in the clinic and what we're learning about movement within the field of neuroscience."" A lower score indicated a greater risk for autism, with numbers under a certain threshold corresponding to previous diagnosis of autism.","The unbiased non-exponential contribution to s-IPI cannot distinguish, for example, one case with two small outlier intervals of equal length ""t"" from another outlier with a single interval of length ""2t"". The speed profile of the latter case is smoother, having the s-Peaks less random. Theoretically, R is proportional to the non-exponential ratio as well as the mean value of the non-exponential distributions (details given in the Supplementary Material).",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1038/s41598-017-03627-7,Psychology_easy_134,This is very true.,"This could also include parent-child, sibling, and best-friend interactions, in comparison to the interactions between strangers.","The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting. ""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands."" This is very true.","Therefore, future research should test the effect of touch and pain in both men and women as well as in homosexual and heterosexual participants. This could also include parent-child, sibling, and best-friend interactions, in comparison to the interactions between strangers. Second, this study used a single subjectively adjusted degree of heat pain.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1038/s41598-017-18902-w,Psychology_easy_135,"""We really need to narrow the gap between what physicians observe in patients in the clinic and what we're learning about movement within the field of neuroscience.""",Similar accuracy (above 90%) was obtained when we chose 70% of the data as training data with the remaining data as test set (details in Methods).,"The assessments are also difficult to administer to very young children, or to people with impairments such as lack of verbal skills, potentially preventing early interventions for these groups. ""We really need to narrow the gap between what physicians observe in patients in the clinic and what we're learning about movement within the field of neuroscience."" A lower score indicated a greater risk for autism, with numbers under a certain threshold corresponding to previous diagnosis of autism.",The data set classification accuracy is 95.45%. Similar accuracy (above 90%) was obtained when we chose 70% of the data as training data with the remaining data as test set (details in Methods). Figure 5C shows a clear separation between immature and mature TD individuals in the R-space.,[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1111/cdev.12250,Psychology_easy_136,"When it ended, they were 23.","In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time .","Allen and his team found evidence to suggest that this behavior might actually hurt social status in school. When it ended, they were 23. The average family range of annual income was $40,000 to $59,999 and about 58% of the subjects described themselves as Caucasian, 29% as African-American, 8% as mixed race and ethnicity, and 5% as being from other minority groups.","With respect to alcohol and marijuana use, early adolescent pseudomature behavior was actually a better predictor of future such substance use problems in adulthood than were even early adolescent levels of such use. In fact, after accounting for pseudomature behavior, early adolescent levels of substance use became insignificant as predictors of future use, suggesting that to the extent that pseudomature behavior and substance use were correlated in early adolescence, it was pseudomature behavior that took on the primary role in statistically predicting future substance use -a striking degree of heterotypic continuity for a behavior that typically displays considerable homotypic continuity over time . This finding indicates just how potentially important this social pathway toward future difficulties may be in identifying individuals at risk for long-term problems with alcohol and substance use.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1016/j.jalz.2018.06.2856,Psychology_easy_138,Patients with the degenerative disease were at a 40 percent to 50 percent greater risk of developing Alzheimer's disease than those without these eye conditions in the study.,"Using an alternate criterion for glaucoma diagnosis such as the use of glaucoma medications in addition to International Classification of Diseases, 9th revision, codes may have produced different findings.","The eye even has the same type of tissues as the brain, the researchers said. Patients with the degenerative disease were at a 40 percent to 50 percent greater risk of developing Alzheimer's disease than those without these eye conditions in the study. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss.""","The prevalence of glaucoma in our cohort was higher than that reported for the US population . Using an alternate criterion for glaucoma diagnosis such as the use of glaucoma medications in addition to International Classification of Diseases, 9th revision, codes may have produced different findings. The AMD effect appears to be both recent and long-term, given highest risk with recent diagnosis and increasing trend with longer duration of AMD.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34761732564&p=1pl&v=1&x=Vhq6mvjHkQ2mz_7WovQGRw
10.1007/s13524-014-0321-x,Psychology_easy_140,"On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE.","Although the overall FE versus OLS differences are not large, they still suggest that the FE model captures unobserved confounders that are not included in the OLS model.","This seemed to be true for the second child as well. On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages.","Such anticipation effects are not surprising because the process of childbearing from planning to birth may take years. Although the overall FE versus OLS differences are not large, they still suggest that the FE model captures unobserved confounders that are not included in the OLS model. Figure 1 shows two differences in happiness trajectories for women and men.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1111/cdev.12250,Psychology_easy_142,"""The student who was popular and was running with the fast crowd isn't doing as great later on.""","Although no measures of pubertal status were available in this study, by the ages of 13-15, the period during which pseudomature behavior was observed, the vast majority of teens are well into puberty.","Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse. ""The student who was popular and was running with the fast crowd isn't doing as great later on."" By about 22, the cool group had a 45 percent higher rate of problems related to alcohol and substance abuse.","Second, one question that might be asked regarding these findings is how they relate to the pubertal status of early adolescents, which has been inconsistently linked to delinquent and romantic behavior . Although no measures of pubertal status were available in this study, by the ages of 13-15, the period during which pseudomature behavior was observed, the vast majority of teens are well into puberty. This fact, plus the lack of consistent links between pubertal timing and delinquent and romantic behavior in the existing literature, suggests that prior differences in pubertal timing are unlikely to account for the findings observed.",[1],Psychology,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1038/s41598-017-03627-7,Psychology_easy_143,They probably had no idea that their poppy little ditty had a basis in scientific fact.,It is important to note that our findings of interpersonal coupling during touch can also be explained by the phenomenon of Huygens synchronization of two connected pendulum clocks 83 .,""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being. They probably had no idea that their poppy little ditty had a basis in scientific fact. That's almost as many as the entire population of Texas.","Thus, future research should test the role of oxytocin in touch-related analgesia. It is important to note that our findings of interpersonal coupling during touch can also be explained by the phenomenon of Huygens synchronization of two connected pendulum clocks 83 . Nevertheless, the moderation effects of empathic accuracy and pain analgesia reduce the probability of this explanation.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1093/jcr/ucw012,Psychology_easy_144,"By the time it dropped below 30%, she was ""not having fun anymore.""",Study 2 also provides evidence that behaviorally targeted ads have unique effects relative to an identity salience prime and demonstrates that the effects of behaviorally targeted ads on purchase intentions persist over time.,"One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious. By the time it dropped below 30%, she was ""not having fun anymore."" ""Anything less than half full, however, induced feelings of profound anxiety and discomfort.""",Study 2 demonstrates that the effects of behavioral targeting on purchase intentions are mediated by the recognition that the ad implies something about the consumer's identity and the subsequent adjustments in self-perceptions that result from recognizing this implied label. Study 2 also provides evidence that behaviorally targeted ads have unique effects relative to an identity salience prime and demonstrates that the effects of behaviorally targeted ads on purchase intentions persist over time. Study 3 shows that the serial mediation tested in study 2 holds not just for purchase intentions for the advertised product but also for other behaviors conceptually related to the label.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-017-03627-7,Psychology_easy_145,"For further information, please contact the cited source.","We found significant moderation of the effect of women's analgesia and touch on the cross-partner synchronization in velocity of respiration fluctuations (F (4,28000) = 26.59, p < 0.0001, ΔBIC = −418367.9, ΔR 2 = 0.19).","For now, he has some advice for partners in the delivery room: Be ready and available to hold your partner's hand. Note: material may have been edited for length and content. For further information, please contact the cited source.","The corresponding contrasts were not significant in the condition without partner touch (Δζ nt(p) = 0.002, p = 0.56, men), (Δζ nt(p) = 0.001, p < 0.73, women) ( Fig. We found significant moderation of the effect of women's analgesia and touch on the cross-partner synchronization in velocity of respiration fluctuations (F (4,28000) = 26.59, p < 0.0001, ΔBIC = −418367.9, ΔR 2 = 0.19). Higher levels of women's analgesia predicted increased coupling between female velocity and male acceleration (Δζ t(p) = 0.027, p < 0.001, 95% CI [0.015, 0.039]) and increased associations between male velocity and female acceleration (Δζ t(p) = 0.068, p < 0.001, 95% CI [0.042, 0.093]) in the touch condition.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1073/pnas.1702671114,Psychology_easy_146,"The new information may lead to better understanding of and treatment for diseases, such as Parkinson's, where the Lombard effect may be amplified, researchers say.","These findings can now be extended to models and measures of audiomotor integration in other animals, including humans.","""We resolved this question."" The new information may lead to better understanding of and treatment for diseases, such as Parkinson's, where the Lombard effect may be amplified, researchers say. It could also help point the way to assistive medical devices.","We show that the Lombard effect operates by continuously integrating the sound pressure level of background noise through temporal summation to guide the extremely rapid vocal-motor adjustments. These findings can now be extended to models and measures of audiomotor integration in other animals, including humans. This is particularly true regarding the control of vocalizations, which are used by a wide range of animal species for communication.",[1],Psychology,train,1.0,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1038/s41598-017-03627-7,Psychology_easy_147,This is very true.,"Empathic accuracy and touch moderated the effect of synchronization in heart rate (F (4,13000) = 20.73, p < 0.0001, ΔBIC = −265162.9, ΔR 2 = 0.24).","The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting. ""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands."" This is very true.","The same pattern of moderation effects emerged in the heart rate analysis. Empathic accuracy and touch moderated the effect of synchronization in heart rate (F (4,13000) = 20.73, p < 0.0001, ΔBIC = −265162.9, ΔR 2 = 0.24). High as opposed to low levels of empathic accuracy predicted greater coupling between female velocity and The corresponding contrasts were not significant in the condition without partner touch (Δζ nt(p) = 0.008, p = 0.28, males), (Δζ nt(p) = 0.008, p = 0.34, females).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1080/09500693.2018.1540897,Psychology_easy_150,"""European institutions had significantly higher grades than North American institutions, suggesting that perhaps the well-known progressive policies of European countries aimed at supporting working parents and promoting work-life balance have some influence on the retention and promotion of women in science,"" Dr. Beeler says.",Most of the excluded studies lacked information about the sampling and/or the assignment of the control group and intervention group.,"Shutterstock

However, there were bright spots. ""European institutions had significantly higher grades than North American institutions, suggesting that perhaps the well-known progressive policies of European countries aimed at supporting working parents and promoting work-life balance have some influence on the retention and promotion of women in science,"" Dr. Beeler says. The Report Card also showed that several STEM institutions had started programs like unconscious bias training to help female scientists flourish.","Only nine studies met the standards such that solid conclusions could be drawn about the effectiveness of the intervention. Most of the excluded studies lacked information about the sampling and/or the assignment of the control group and intervention group. For example, by purposeful choice of participants by teachers, or the choice of an existing group as a control group without controlling for group characteristics such as gender, ability and/or motivation, causing possibly unequal groups (internal threat of selection).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1111/cdev.12250,Psychology_easy_151,"By about 22, the cool group had a 45 percent higher rate of problems related to alcohol and substance abuse.",This full sample thus provides the best possible estimates of variances and covariances in measures of interest and was least likely to be biased by missing data.,"""The student who was popular and was running with the fast crowd isn't doing as great later on."" By about 22, the cool group had a 45 percent higher rate of problems related to alcohol and substance abuse. They were also more likely to have engaged in criminal workings.","Because these procedures have been found to yield the least biased estimates when all available data are used for longitudinal analyses (vs. listwise deletion of missing data; , the entire original sample of 184 was utilized for these analyses. This full sample thus provides the best possible estimates of variances and covariances in measures of interest and was least likely to be biased by missing data. Alternative longitudinal analyses using just those participants without missing data (i.e., listwise deletion) yielded results that were substantially identical to those reported in the following.",[1],Psychology,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1016/j.jpeds.2017.10.028,Psychology_easy_152,This abdication of the moral high ground is principled.,Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth.,"Temple is less direct: ""The point of us doing this research isn't to tell parents what to do,"" he said, conjuring a libertarian-friendly approach to science. This abdication of the moral high ground is principled. He is fundamentally opposed to telling people what not to do.","One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence. Attaining a better understanding of antecedents of dating violence is critical for preventive strategies seeking to mitigate dating violence among youth. These factors cut across various domains including affective (eg, emotion dysregulation, psychiatric disorder), cognitive (eg, attitudes toward women, beliefs about violence), demographic (eg, age, race, sex, sexual orientation, socioeconomic status), interpersonal (eg, relationship satisfaction, problem solving skills), contextual (eg, availability of weapon, drug/alcohol use), as well as distal factors (eg, history of child abuse, exposure to family violence).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1038/s41598-017-18902-w,Psychology_easy_153,"""We've found that every person has their own unique 'movement DNA,'"" says senior author Jorge V. Jose, professor of physics at Indiana University Bloomington.","The R-parameter value for this case is 24.9, suggesting also an experimental minimum threshold for R. Notice that some subjects in the ASD group have R values below 30 for ages above 10, even for the 30-years old ASD subject.","The study's results, reported in Scientific Reports, suggest a more accurate method to diagnose autism. ""We've found that every person has their own unique 'movement DNA,'"" says senior author Jorge V. Jose, professor of physics at Indiana University Bloomington. ""The use of movement as a 'biomarker' for autism could represent an important leap forward in detection and treatment of the disorder.""","2A) , with the corresponding s-IPI distribution close to an exponential (Fig. The R-parameter value for this case is 24.9, suggesting also an experimental minimum threshold for R. Notice that some subjects in the ASD group have R values below 30 for ages above 10, even for the 30-years old ASD subject. This remarkable result suggests a total absence of age-related neurodevelopmental milestones in these ASD cases.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1016/j.nicl.2013.09.001,Psychology_easy_154,"That could allow the physician to get an early start on the treatment.""","A total of 18 scans had sufficient artifact that they could not be used for the present study, leaving a total of 283 MRI scans at baseline (when all participants were cognitively normal) and 333 MRI scans obtained over time (controls = 269, preclinical AD = 64).","Also, the scans in our library may help a physician identify a change in the shape of a brain structure that occurs very early in the course of a disease, even before clinical symptoms appear. That could allow the physician to get an early start on the treatment."" Mori points out that such a ""biobank"" has the potential to impact doctors' workflow dramatically.","Of the 51 participants with preclinical AD, 33 had repeat MRI scans (M = 2.94/subject). A total of 18 scans had sufficient artifact that they could not be used for the present study, leaving a total of 283 MRI scans at baseline (when all participants were cognitively normal) and 333 MRI scans obtained over time (controls = 269, preclinical AD = 64). approach defines the caudal extent relative to the lateral geniculate nucleus.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1038/s41598-017-18902-w,Psychology_easy_155,"The greater amount of fluctuation in the movement of the individuals with autism was possibly related to the level of ""noise"" naturally produced by random neuron firings in the brain, for which neurotypical individuals seem to develop stronger compensation methods.",The p-values for the correlation between R-parameter and ADI-R sum score were slightly above 0.05 (below 0.05 when we exclude the outlier subject).,"A lower score indicated a greater risk for autism, with numbers under a certain threshold corresponding to previous diagnosis of autism. The greater amount of fluctuation in the movement of the individuals with autism was possibly related to the level of ""noise"" naturally produced by random neuron firings in the brain, for which neurotypical individuals seem to develop stronger compensation methods. In each case, the movement-based diagnoses corresponded to these qualitative-based assessments, which are rarely in complete agreement.","(2) Our R-parameter is modestly correlated (negative) with ASD severity level in the spectrum. The p-values for the correlation between R-parameter and ADI-R sum score were slightly above 0.05 (below 0.05 when we exclude the outlier subject). We didn't find, however, a direct correlation between our R parameter and the ADOS score.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1007/s13524-014-0321-x,Psychology_easy_156,Ja nos Estados Unidos mais de metade dos adultos opta por ter dois filhos e um terco tres.,"If people see young parents with few resources having a difficult time and others with many resources having an easier time, this may send a message to postpone childbearing.","A maioria dos europeus adultos considera que a familia ideal e composta por dois filhos, nem mais nem menos. Ja nos Estados Unidos mais de metade dos adultos opta por ter dois filhos e um terco tres. Estes resultados podem estar a ser manipulados por aquilo a que se chama o 'numero normal' de filhos nas civilizacoes ocidentais.","Older parents may be more ""ready"" for parenthood or may have been anticipating it more intently . If people see young parents with few resources having a difficult time and others with many resources having an easier time, this may send a message to postpone childbearing. Even if intentions are high, postponement may contribute to lower quantum because of declining fecundity.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1016/j.jarmac.2014.03.005,Psychology_easy_157,"Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign.","Most of the coded features are fairly unambiguous and easily verified in any case, leaving little room for error.","Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs. Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign. ""[T]hey are likely to 'remember' scandals that reflect poorly on the opposing candidate,"" Murphy told the Association for Psychological Science.","This post-warning studies landscape was fairly heterogeneous in terms of the general (i.e., not warning-related) study characteristics, but always within a typical range, and is in this sense reflects the breadth of misinformation research in general. Most of the coded features are fairly unambiguous and easily verified in any case, leaving little room for error. Because the odds ratios are more intuitive, however, we report all results as re-transformed into this format.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1007/s13524-014-0321-x,Psychology_easy_158,"On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE.","Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms.","This seemed to be true for the second child as well. On the third child, parents inadvertently switched back to their ""pre-child happiness level,"" according to LSE. The happiness level of parents varied among different ages.","A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth . Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms. Second, social norms about childbearing have relaxed markedly over the study period, and when and how many children to have may be more of a decision than before.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1038/s41598-017-18902-w,Psychology_easy_159,"The study's results, reported in Scientific Reports, suggest a more accurate method to diagnose autism.","From the convolution theorem, the Fourier transform of the filtered data equals the product of the Fourier transform of the raw data times the Fourier transform of the triangular function:","The study's results, reported in Scientific Reports, suggest a more accurate method to diagnose autism. ""We've found that every person has their own unique 'movement DNA,'"" says senior author Jorge V. Jose, professor of physics at Indiana University Bloomington. ""The use of movement as a 'biomarker' for autism could represent an important leap forward in detection and treatment of the disorder.""","The triangular function can be written as: From the convolution theorem, the Fourier transform of the filtered data equals the product of the Fourier transform of the raw data times the Fourier transform of the triangular function: Notice that the application of the smoothing algorithm to the velocity profiles is equivalent to the application to the raw positional readings directly.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1111/cdev.12250,Psychology_easy_162,"""We suspect they may have then engaged in more and more extreme behaviors trying to gain peer approval,"" Allen said.",Two of the three behaviors in the pseudomature cluster examined in this study were not even considered deviant.,"And as the cohort got older, these mature behaviors got a forceful shove into full-blown recklessness. ""We suspect they may have then engaged in more and more extreme behaviors trying to gain peer approval,"" Allen said. In other words, ""those who got approval for drinking at 13 had to get wasted multiple times and engage in more extreme acts to try, unsuccessfully, to gain approval in later years.""","Importantly, the predictions to future problematic behaviors were not a reflection of simple continuities over time in levels of deviance. Two of the three behaviors in the pseudomature cluster examined in this study were not even considered deviant. More importantly, early adolescent pseudomature behavior had value in predicting future criminal behavior and alcohol and marijuana use problems over and above early adolescent markers of such problems.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1093/jcr/ucw012,Psychology_easy_163,"""In a sense, you become more like what the ads say you are.",Study 2 sheds light on this process by measuring consumers' self-perceptions.,"It actually makes you feel more environmentally conscious and can change your behavior,"" said Rebecca Walker Reczek, co-author of the study and associate professor of marketing at The Ohio State University's Fisher College of Business. ""In a sense, you become more like what the ads say you are. Study participants who were told that the ad was targeted to them because of their Internet browsing history were more likely than others to say that the ad suggested they had ""sophisticated food preferences.""","The data also show that the effects of behavioral targeting are not due to differences in liking for the advertisement because consumers liked the ad equally in all conditions. Study 2 sheds light on this process by measuring consumers' self-perceptions. Second, we increase the external validity of our work by manipulating awareness of whether the ad is behaviorally targeted using the industry-standard AdChoices icon.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1007/s13524-014-0321-x,Psychology_easy_166,This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small.,"Social norms and social policy may play some role in shaping parental wellbeing trajectories, but overall, the individual sociodemographic characteristics are more important than context.","""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report. This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small. The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby.","The resulting differences in poverty are not small: 40 % to 46 % of lone mothers in Britain are poor, compared with only 27 % to 30 % in Germany . Social norms and social policy may play some role in shaping parental wellbeing trajectories, but overall, the individual sociodemographic characteristics are more important than context. The happiness trajectories of parents were quite similar in the pooled cross-sectional OLS regressions and the fixed-effects regressions.",[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1007/s13524-014-0321-x,Psychology_easy_167,"Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.",The FE results are qualitatively consistent with those obtained with the OLS model and similar in Germany and Britain as well as across the two happiness measures available in the BHPS.,"The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.","Age at first birth also shows a positive gradient with happiness. The FE results are qualitatively consistent with those obtained with the OLS model and similar in Germany and Britain as well as across the two happiness measures available in the BHPS. The main difference between the OLS and the FE models is that the happiness increase in the years preceding birth and in the year of birth is somewhat stronger in the FE specification, and the decrease in post-birth decline is not quite as strong in the FE specification.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_easy_168,"And if you were like most high school students, what you wanted was to be cool -- and more specifically, for other cool kids to notice you were cool.","To the extent that pseudomature behavior supplants other, more positive, and adaptive ways of interacting with peers, it may leave teens less socially skilled and less competent in peer relationships.","And if you were like most high school students, what you wanted was to be cool -- and more specifically, for other cool kids to notice you were cool. Well, it turns out whoever doled out that advice was, in fact, right. None of this is necessarily new information, not to parents at least, but Joseph Allen, the leader of the new study, believes learning how teenagers come to manifest certain behaviors and express them over a long timeline, is helpful for teaching kids a safer way to be cool.","As peers grow from adolescence into adulthood and gain real maturity along the way, they are less likely to find pseudomature behavior in others attractive. To the extent that pseudomature behavior supplants other, more positive, and adaptive ways of interacting with peers, it may leave teens less socially skilled and less competent in peer relationships. This perspective suggests that the observed link between pseudomature behavior and popularity will fade as adolescence progresses and that reliance upon pseudomature behavior early in adolescence might ultimately predict lower levels of competence in social relationships in the longer term, although neither of these premises has ever been empirically tested.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1176/appi.ajp.2018.17111282,Psychology_easy_170,The doctor still isn't supposed to suggest changing medication until they have you genetically tested again by an independent lab.,"Among 14 medications, sertraline was the most commonly prescribed antidepressant for both treatment groups (18.9% in the guided treatment group and 16.2% in the treatment-as-usual group), and no significant differences were observed between groups in medication choice.","To win approval, the company had to run a demographically representative study proving that 97 percent of users understand that the test is not a medical recommendation, says 23andMe chief legal and regulatory officer Kathy Hibbs. The doctor still isn't supposed to suggest changing medication until they have you genetically tested again by an independent lab. ""It seems to me that if a patient has an interest in their pharmacogenetic profile that could impact medication decisions, they're probably better off just asking the physician about what testing can be done, since confirmatory testing is expected anyway even if you got 23andMe,"" says Boadie Dunlop, an Emory University psychiatrist who researchers biological markers that predict responses to drug treatments.","Furthermore, those in the treatment-as-usual group were more likely to take sick leave (4% in the guided treatment group compared with 15% in the treatment-as-usual group; p=0.027), whereas the duration of sick leave was longer (7.7 days compared with 4.3 days; p=0.014) for the treatment-as-usual group. Among 14 medications, sertraline was the most commonly prescribed antidepressant for both treatment groups (18.9% in the guided treatment group and 16.2% in the treatment-as-usual group), and no significant differences were observed between groups in medication choice. Unlike many antidepressants, desvenlafaxine is metabolized by UGT1A1 rather than by CYP450 enzymes.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1093/jcr/ucw012,Psychology_easy_171,"""One of the most striking things about this study was that people weren't aware they were making these big mistakes,"" says Julie Golomb, co-author of the study and an associate professor of psychology at Ohio State's Center for Cognitive and Brain Sciences.",The model estimated a significant in-,"Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice. ""One of the most striking things about this study was that people weren't aware they were making these big mistakes,"" says Julie Golomb, co-author of the study and an associate professor of psychology at Ohio State's Center for Cognitive and Brain Sciences. Her study's findings imply that visual distractions -- like the ones caused by the flash of a ""new message"" alert or a news update -- might distort a person's memory of an event or interaction without that person realizing it.","There was no difference in willingness to purchase the Groupon between participants in the demographically targeted and nontargeted conditions (F(1, 185) ¼ .35, p ¼ .56) (figure 1). The model estimated a significant in- , .0046-.1719), indicating that behavioral targeting increases purchase intentions for the advertised product through the recognition of the implied social label.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jarmac.2014.03.005,Psychology_easy_172,"In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events.",", impaired memory performance for original event details and misinformation endorsement.","""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events. It's a problem that psychological scientists may be uniquely qualified to work on.""","This holds about equally for both core measures of the misinformation effect (cf. , impaired memory performance for original event details and misinformation endorsement. Further, with respect to original event memory, the benefits of post-warnings in terms of improving misled performance clearly outweigh any costs in terms of reduced 0 1 2 3",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1177/0141076814565942,Psychology_easy_173,The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families.,"Psychological problems were encountered in 4% of children aged < years at the time of operation, as compared with 0% among older children.","They found that regardless of cultural background circumcised boys may run a greater risk of developing ASD. The researchers also made the observation of an increased risk of hyperactivity disorder among circumcised boys in non-Muslim families. Risk was particularly high for infantile autism before the age of five, at least in epidemiology.","Among children operated for a variety of conditions, Levy noted a strong association between the age at operation and the frequency and severity of emotional sequelae. Psychological problems were encountered in 4% of children aged < years at the time of operation, as compared with 0% among older children. showed that even the youngest infants had full capacity for conscious perception, although their ability to express such perceptions had not yet developed.",[1],Psychology,train,1.0,news,http://www.science20.com/news_articles/circumcision_linked_to_autism_study-152121
10.1007/s13524-014-0321-x,Psychology_easy_174,This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small.,"Moreover, happiness increases before birth, suggesting that the trajectories may capture not only the effect of the birth but also the broader process of childbearing, which may include partnership formation and quality.","""We find that the happiness gain around the time of childbirth attenuates with parity, being strongest for the first, lower for the second, and nonpositive for the third child,"" the sociologists report. This finding combined with the classic psychological learning theory can explain why the number of parents having three children is so small. The researchers think that the perception of decreasing satisfaction diminishes motivation to have one more baby.","Consistent with existing work, we find that happiness increases in the years around the birth of a first child and then decreases to before-child levels. Moreover, happiness increases before birth, suggesting that the trajectories may capture not only the effect of the birth but also the broader process of childbearing, which may include partnership formation and quality. Sociodemographic factors strongly modify this pattern.",[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1176/appi.ajp.2018.17111282,Psychology_easy_175,"The manufacturer, 23andMe, won FDA approval by being very careful not to overpromise what its test can do-- so careful that the approval highlights the limited usefulness of the test and how much we still don't know about this field of medicine.","Repeated-measures analysis of change in clinical scores over time revealed a significantly greater reduction of symptoms in the GeneSight-guided treatment group than in the treatment-as-usual group after 8 weeks (on the QIDS-C, p,0.001; on the HAM-D, p,0.001; on the Patient Health Questionnaire, p,0.002).","The manufacturer, 23andMe, won FDA approval by being very careful not to overpromise what its test can do-- so careful that the approval highlights the limited usefulness of the test and how much we still don't know about this field of medicine. The 23andMe test will tell consumers about 33 genetic variants that are associated with how well common drugs -- blood thinners like Plavix and Coumadin, for example -- work, but it's explicit that consumers should not change their medications based on these results. The test is only supposed to provide some potentially useful information that people can discuss with their doctor.","However, the short duration of the study, the lack of blinding to mitigate placebo effects, and the modest size of the cohort (N=51) are important limitations. Repeated-measures analysis of change in clinical scores over time revealed a significantly greater reduction of symptoms in the GeneSight-guided treatment group than in the treatment-as-usual group after 8 weeks (on the QIDS-C, p,0.001; on the HAM-D, p,0.001; on the Patient Health Questionnaire, p,0.002). Furthermore, there were significant group differences in the proportion of participants meeting criteria for categorical response (44.4% of the GeneSightguided group, compared with 23.7% the treatment-as-usual group; response was defined as a reduction $50% in QIDS-C score from baseline to endpoint) and remission (26.4% of the guided group, compared with 12.9% of the treatment-as-usual group) at 8 weeks (p=0.03).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1073/pnas.1505114112,Psychology_easy_178,"It found that those who learned music experienced faster maturation in the brain's response to sound, and heightened sensitivity to details in sound.","Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years.","It's for these reasons that musical training improves teens' development. It found that those who learned music experienced faster maturation in the brain's response to sound, and heightened sensitivity to details in sound. While all students showed improvement in language skills necessary for reading, it was those who underwent musical training that performed the best three years later.","These changes seem to benefit literacy skills: both groups improved in phonological awareness relative to the general population, but the music training group improved more compared with the active controls. Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years. Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1016/j.jarmac.2014.03.005,Psychology_easy_179,"The campaign, centering on an emotional debate between two parties with deeply held convictions, turned out to be an ideal opportunity to study the effects of fake news.","better scrutiny of the post-event information), enhanced remembering, or both.","The campaign, centering on an emotional debate between two parties with deeply held convictions, turned out to be an ideal opportunity to study the effects of fake news. ""[T]hey are likely to 'remember' scandals that reflect poorly on the opposing candidate."" This meant that voters were relatively well informed about both sides.","If a pre-warning resulted in a reduced misinformation effect, this could be due to enhanced attention (e.g. better scrutiny of the post-event information), enhanced remembering, or both. Similarly, post-warnings immediately after presentation of misinformation could still affect its encoding and certainly its rehearsal.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1007/s13524-014-0321-x,Psychology_easy_182,Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility.,Our findings open new research questions.,"Instead, this may reflect that the experience of parenthood is less novel and exciting by the time the third child is born or that a larger family puts extra pressure on the parents' resources. Study co-author Rachel Margolis implied that their findings could explain why most people are delaying fertility. Older parents have better financial and education status than younger parents and are also less stressed after the birth of their children.","One cannot infer from our results that the set of control variables used in our regressions would effectively control for selection in some other context. Our findings open new research questions. These might explain why women anticipate a first birth more than men, with stronger happiness increases prior to and around the birth and a larger drop afterward.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1080/14635240.2015.1029641,Psychology_easy_183,"The key takeaway from this research, Benden said, is that school districts that put standing desks in classrooms may be able to address two problems at the same time: academic performance and childhood obesity.",The increase in BMI may be a result of the increasing sedentary lifestyle of children and adolescents .,"Benden said he was not surprised at the results of the study, given that previous research has shown that physical activity, even at low levels, may have beneficial effects on cognitive ability. Simply put, we think better on our feet than in our seat."" The key takeaway from this research, Benden said, is that school districts that put standing desks in classrooms may be able to address two problems at the same time: academic performance and childhood obesity.","In 2009 -2010, obesity rates were as high as 16.9%, and rates for overweight children and adolescents aged 2 -19 were 31.8% (body mass index (BMI) $ 95th percentile and BMI $ 85th percentile based on age and gender norms, respectively) q 2015 Institute of Health Promotion and Education *Corresponding author. The increase in BMI may be a result of the increasing sedentary lifestyle of children and adolescents . Although, there has been stabilization in the rate of increase each year, standards set by Healthy People 2010 were not reached (Services USDoHaH 2000) .",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/04/150424121118.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/s41598-017-18902-w,Psychology_easy_185,"The greater amount of fluctuation in the movement of the individuals with autism was possibly related to the level of ""noise"" naturally produced by random neuron firings in the brain, for which neurotypical individuals seem to develop stronger compensation methods.","It is, however, questionable whether the visually smooth movement outputs, especially the speed profiles, are perfectly smooth with no fluctuations at all at shorter time scales, away from naked eye observations.","A lower score indicated a greater risk for autism, with numbers under a certain threshold corresponding to previous diagnosis of autism. The greater amount of fluctuation in the movement of the individuals with autism was possibly related to the level of ""noise"" naturally produced by random neuron firings in the brain, for which neurotypical individuals seem to develop stronger compensation methods. In each case, the movement-based diagnoses corresponded to these qualitative-based assessments, which are rarely in complete agreement.","The nervous system seems to have developed strategies to compensate for the different sources of all internal noise present. It is, however, questionable whether the visually smooth movement outputs, especially the speed profiles, are perfectly smooth with no fluctuations at all at shorter time scales, away from naked eye observations. This smoothing algorithm successfully filtered out the spurious electronic noise while preserving the detailed movement physiological information in the output, in particular in the local speed fluctuations.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1016/j.jpeds.2017.10.028,Psychology_easy_186,"As a psychologist, I find this to be a frequent topic of conversation and debate with parents.","Finally, corporal punishment was associated with future physical perpetration of dating violence, even after controlling for demographic variables (ie, sex, ethnicity, age, parental education), as well as a history of childhood physical abuse.","Differences in opinions on spanking also differ across ethnic groups and educational backgrounds. As a psychologist, I find this to be a frequent topic of conversation and debate with parents. My preference is to encourage positive behavioral management and decrease the use of punishment.","Fourth, parent education (as a proxy for socioeconomic status) was linked to teen dating violence-specifically, that participants with lower socioeconomic status were more likely to perpetrate teen dating violence. Finally, corporal punishment was associated with future physical perpetration of dating violence, even after controlling for demographic variables (ie, sex, ethnicity, age, parental education), as well as a history of childhood physical abuse. The finding that childhood corporal punishment was linked to perpetration of dating violence even after controlling for covariates underscores the importance of corporal punishment when considering partner violence etiology.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32818256385&p=1pl&v=1&x=0ZAEkx105k29I5f3n6_nlQ
10.1093/schbul/sbv109,Psychology_easy_187,"Their work provides additional evidence that this region may provide valuable information that could be used to inform diagnostic evaluations in not only schizophrenia but other Axis I disorders such as bipolar disorder, depression, addiction, obsessive-compulsive disorder and anxiety regardless of ethnicity.","Post hoc t tests indicated that these differences were driven by the Chinese group having higher scores in PANSS total, PANSS positive, and PANSS general than the Japanese, African-Caribbean, and White Caucasian groups (P < .001); in contrast, the 4 groups did not differ in terms of PANSS negative scores (F[3,112] = 1, P = .39).","Building upon previous research showing consistent gray matter reduction in the right anterior insulaaEUR""evident after a single episode of the illnessaEUR""the authors conclude this reduction exists regardless of ethnic background. Their work provides additional evidence that this region may provide valuable information that could be used to inform diagnostic evaluations in not only schizophrenia but other Axis I disorders such as bipolar disorder, depression, addiction, obsessive-compulsive disorder and anxiety regardless of ethnicity. ###

The paper aEURoeA Neuroanatomical Signature for Schizophrenia Across Different Ethnic GroupsaEUR can be accessed here: http://schizophreniabulletin.oxfordjournals.org/content/early/2015/08/10/schbul.sbv109.full?sid=a9367e61-bbdf-4a49-9772-cd42ee6cb619

Note to Reporters:

Any mention or reporting of data from this article should be attributed to: Schizophrenia Bulletin, published by Oxford University Press, seeks to review recent developments and empirically based hypotheses regarding the etiology and treatment of schizophrenia.","In contrast, there were no differences between the Chinese and White Caucasian groups (P = . Post hoc t tests indicated that these differences were driven by the Chinese group having higher scores in PANSS total, PANSS positive, and PANSS general than the Japanese, African-Caribbean, and White Caucasian groups (P < .001); in contrast, the 4 groups did not differ in terms of PANSS negative scores (F[3,112] = 1, P = .39). In addition, there was a difference in duration of illness (F[3,122] = 6.76, P = .0003) across groups (table 1).",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/researchers-find-neuroanatomical-signature-for-schizophrenia/
10.1016/j.jalz.2018.06.2856,Psychology_easy_189,Cataract diagnosis was not an Alzheimer's disease risk factor.,It is common to evaluate risk factors in the larger group of people with clinical diagnoses and attempt to confirm those risk factors with more specific neuropathology data in the smaller subset of individuals who have died and come to autopsy.,"Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions. Cataract diagnosis was not an Alzheimer's disease risk factor. ""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine.","Nevertheless, there is still an imperfect relationship between NINCDS-ADRDA clinical diagnoses of AD and neuropathological Alzheimer's findings of neuritic plaques and neurofibrillary tangles . It is common to evaluate risk factors in the larger group of people with clinical diagnoses and attempt to confirm those risk factors with more specific neuropathology data in the smaller subset of individuals who have died and come to autopsy. Even though our primary outcome was clinical AD diagnosis, we found similar relationships with all-cause dementia with all three ophthalmic conditions (Supplementary Table 1 ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1111/cdev.12250,Psychology_easy_191,"For these teens, being popular was their highest goal, Allen said.","These analyses indicate numerous simple correlations between early adolescent pseudomature behaviors (i.e., minor deviance, selection of attractive peers, precocious romantic behavior), and initial (but not later) levels of popularity, and between these early pseudomature behaviors and later negative outcomes, all of which are explored further below.","What researchers found was that the kids considered cool in the 8th grade had already peaked by the time they reached high school. For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol.","For descriptive purposes, Table 1 also presents simple correlations among all primary constructs examined in the study. These analyses indicate numerous simple correlations between early adolescent pseudomature behaviors (i.e., minor deviance, selection of attractive peers, precocious romantic behavior), and initial (but not later) levels of popularity, and between these early pseudomature behaviors and later negative outcomes, all of which are explored further below. Valuing of popularity was a significant predictor of each of these behaviors after accounting for gender and income (b = .15, p = .01; b = .20, p = .004; b = .16, p = .04, for minor delinquency, attractiveness of close peer, and precocious romantic activity, respectively).",[1],Psychology,train,1.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1038/s41598-017-18902-w,Psychology_easy_192,The new motion data strengthens evidence for movement as a biomarker for autism.,"1B , the average/ maximum hand speed during the motion cycles, as well as the temporal length of the average motion cycle durations are not separable between ASD and TD.","Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism. Next, the researchers aim to conduct movement assessments on more people, including more research on the parents of children with autism to better understand the connection between lower parental scores on the movement assessment and their children's risk for autism.","As shown in the histograms in Fig. 1B , the average/ maximum hand speed during the motion cycles, as well as the temporal length of the average motion cycle durations are not separable between ASD and TD. The average speed profiles across cycles show similar bell-shape-like curves for all subjects (Fig.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1111/cdev.12250,Psychology_easy_193,"Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse.","Alternative longitudinal analyses using just those participants without missing data (i.e., listwise deletion) yielded results that were substantially identical to those reported in the following.","In fact, researchers discovered that by around 22, most school celebrities had been denoted to just your average Joe. Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse. ""The student who was popular and was running with the fast crowd isn't doing as great later on.""","This full sample thus provides the best possible estimates of variances and covariances in measures of interest and was least likely to be biased by missing data. Alternative longitudinal analyses using just those participants without missing data (i.e., listwise deletion) yielded results that were substantially identical to those reported in the following. In sum, analyses suggest that attrition was very low in terms of target adolescent participation, and even where higher (i.e., in terms of obtaining collateral peer data), was only linked to one baseline measure that was included in analyses and thus not likely to have distorted any of the findings reported.",[1],Psychology,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1093/jcr/ucw012,Psychology_easy_194,"While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals.",Explicit social labels reinforce this tendency to learn about the self and evaluate the implications of one's behavior by providing a characterization of the self from an external source.,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains. While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals. Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner.","These findings are consistent with self-perception theory , which proposes that people perceive themselves to have certain qualities as a result of observing their own behavior and act according to the traits they believe they possess. Explicit social labels reinforce this tendency to learn about the self and evaluate the implications of one's behavior by providing a characterization of the self from an external source. He also joins in suggesting that persuasive statements like ""American consumers must be more energy conscious"" can serve as implicit social labels, whereas ""American consumers are not energy conscious"" would be an explicit social label.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdep.12038,Psychology_easy_195,The number of incidents in a single family varied from one to 10.,"But the findings were based on a comparison of postintervention rates of compliance, which is typical for random assignment experiments, and failed to consider the fact that the comparison groups in two of the five studies had substantially different rates of initial compliance at baseline.",The tape recordings revealed 41 incidents of corporal punishment in 15 of the families. The number of incidents in a single family varied from one to 10. The median age of the children was 4 years.,"In an initial meta-analysis of these studies, children were more likely to comply when mothers spanked than when they used time-outs . But the findings were based on a comparison of postintervention rates of compliance, which is typical for random assignment experiments, and failed to consider the fact that the comparison groups in two of the five studies had substantially different rates of initial compliance at baseline. When the data were reanalyzed to compare the pre-to postintervention changes in compliance for spanking with those for time-outs to take the baseline differences into account, spanking was not found to be more effective than time-outs at increasing children's immediate compliance to mothers' commands ).",[1],Psychology,train,1.0,news,http://www.minnpost.com/second-opinion/2014/04/parents-often-spank-out-anger-and-trival-reasons-real-time-study-finds
10.1093/jcr/ucw012,Psychology_easy_196,"""One of the most striking things about this study was that people weren't aware they were making these big mistakes,"" says Julie Golomb, co-author of the study and an associate professor of psychology at Ohio State's Center for Cognitive and Brain Sciences.","These findings are consistent with self-perception theory , which proposes that people perceive themselves to have certain qualities as a result of observing their own behavior and act according to the traits they believe they possess.","Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice. ""One of the most striking things about this study was that people weren't aware they were making these big mistakes,"" says Julie Golomb, co-author of the study and an associate professor of psychology at Ohio State's Center for Cognitive and Brain Sciences. Her study's findings imply that visual distractions -- like the ones caused by the flash of a ""new message"" alert or a news update -- might distort a person's memory of an event or interaction without that person realizing it.","For example, found that people who were explicitly labeled ""charitable"" after donating to a charity were more likely to contribute to a second charity than people who had also donated but were not labeled. These findings are consistent with self-perception theory , which proposes that people perceive themselves to have certain qualities as a result of observing their own behavior and act according to the traits they believe they possess. Explicit social labels reinforce this tendency to learn about the self and evaluate the implications of one's behavior by providing a characterization of the self from an external source.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1073/pnas.1322295111,Psychology_easy_197,Results from this task demonstrated that subjects with injuries to their insula tended to not be biased by the frequency that either color ended up being chosen.,"In conclusion, we provide neuropsychological evidence for the causal involvement of the insula in two gambling-related cognitive distortions, generating a testable hypothesis of insula over-activity in disordered gambling.","Instead, subjects suffering from these injuries cut their losses and chose to stop playing when they hit a near-miss. Results from this task demonstrated that subjects with injuries to their insula tended to not be biased by the frequency that either color ended up being chosen. Instead, they were likely to stick to the same color trial after trial.","Lastly, the disruption of both the near-miss effect and the gambler's fallacy in the insula cases implies some linkage of these two gambling distortions, raising a broader question of how the various gambling-related cognitive distortions should be organised at a psychological or neural level. In conclusion, we provide neuropsychological evidence for the causal involvement of the insula in two gambling-related cognitive distortions, generating a testable hypothesis of insula over-activity in disordered gambling. For the vmPFC group (see Fig.",[1],Psychology,train,1.0,news,http://arstechnica.com/science/2014/04/brain-damage-can-make-people-immune-to-the-gamblers-fallacy/
10.1016/j.jarmac.2014.03.005,Psychology_easy_199,"Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs.","better scrutiny of the post-event information), enhanced remembering, or both.","This meant that voters were relatively well informed about both sides. Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs. Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign.","If a pre-warning resulted in a reduced misinformation effect, this could be due to enhanced attention (e.g. better scrutiny of the post-event information), enhanced remembering, or both. Similarly, post-warnings immediately after presentation of misinformation could still affect its encoding and certainly its rehearsal.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1111/lcrp.12013,Psychology_easy_200,"It should, according to Nash.","This interview tool could be used alongside other brief techniques shown to be effective, such as focused meditation, mental context reinstatement, and modified Cognitive Interview procedures (e.g., .","Can this revelation help people remember other types of information in other circumstances? It should, according to Nash. ""The mechanisms we identified ought to apply to other contexts, for example trying to remember details of a lecture,"" Nash said.","Therefore, the simple eye-closure instruction could be a useful addition to the investigative interviewer's tool box, particularly in cases in which time is limited. This interview tool could be used alongside other brief techniques shown to be effective, such as focused meditation, mental context reinstatement, and modified Cognitive Interview procedures (e.g., . Perhaps the most important finding from a practical point of view was that eye-closure facilitated one of the main goals of repeated interviewing, namely, reminiscence.",[1],Psychology,train,1.0,news,http://www.techtimes.com/articles/27033/20150118/close-your-eyes-for-better-memory-recall.htm
10.1093/jcr/ucw012,Psychology_easy_202,"Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner.","An interaction did not qualify these results (b ¼ .02, t(131) ¼ .43, p ¼ .66).","While the effectiveness of behaviorally targeted ads is great news for marketers, these findings bring up some troubling hypotheticals. Based on Reczek's findings, these sorts of ads could strengthen that young person's perception of themselves as a certain kind of gun owner. ""If people don't see the trait implied by an ad as negative, our research suggests that they would see themselves as having the trait to a greater extent,"" she says.","). An interaction did not qualify these results (b ¼ .02, t(131) ¼ .43, p ¼ .66). Floodlight analysis using the Johnson-Neyman technique revealed a significant positive effect of behavioral targeting on participants' self-perceptions of outdoorsiness only among participants who made four through nine outdoors-related choices in the shopping task (i.e., at moderate and high levels of accuracy; B JN ¼ .28, SE ¼ .14, p ¼ .05).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.3402/ejpt.v5.22250,Psychology_easy_205,"We are also tired of the 'evil alter' trope that is portrayed time and time again in media.a

I fully believe I would not be here today if it wasn't for my system.","For highbetrayal trauma after age 18, the mean score was 9.20 (SD 04.57).","We had similar experiences in the medical community and in everyday life. We are also tired of the 'evil alter' trope that is portrayed time and time again in media.a

I fully believe I would not be here today if it wasn't for my system. aI would say one very popular misconception is that people with DID donat know they have it or donat know anything about their alters.","Participants had a mean score of 19.10 (SD010.84) for all trauma after age 18. For highbetrayal trauma after age 18, the mean score was 9.20 (SD 04.57). These levels of reported trauma are much higher than those reported by young adult populations (see for comparison results).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1016/j.jalz.2018.06.2856,Psychology_easy_206,"""This paper is pointing to a new area of opportunity,"" he said.","In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not.","She said a better understanding of neurodegeneration in the eye and the brain could bring more success in diagnosing Alzheimer's early and developing better treatments. The researchers said several factors suggest the effects they uncovered were specific to ophthalmic conditions and not merely age-related phenomenon. ""This paper is pointing to a new area of opportunity,"" he said.","Finally, our study only evaluated the temporal sequence that starts with ophthalmic conditions followed by AD and not vice-versa thus we are unable to assess whether increased risk for ophthalmic conditions may exist in individuals with AD. In summary, glaucoma, AMD, and DR are associated with increased AD risk, whereas cataract is not. Subsequent studies of ophthalmic diseases in relation to AD and dementia may provide important insights into shared pathological pathways, thus enabling better techniques to prevent and treat.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1111/cdev.12250,Psychology_easy_207,"When it ended, they were 23.",behaviors predict far greater future risk than has heretofore been recognized.,"Allen and his team found evidence to suggest that this behavior might actually hurt social status in school. When it ended, they were 23. The average family range of annual income was $40,000 to $59,999 and about 58% of the subjects described themselves as Caucasian, 29% as African-American, 8% as mixed race and ethnicity, and 5% as being from other minority groups.","***p < .001. behaviors predict far greater future risk than has heretofore been recognized. In terms of competence with peers, pseudomature behavior in early adolescence predicted not only declining popularity with peers across adolescence but also lower levels of peer competence, as rated by peers, in early adulthood.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1038/nn.3635,Psychology_easy_208,"The MIT team's strategy ""provides a rich new source of evidence on this highly dynamic process,"" says Nikolaus Kriegeskorte, a principal investigator in cognition and brain sciences at Cambridge University.","acc.""","It's just pure automatic machinery that starts every time you open your eyes, and it's incredibly fast,"" Cichy says. The MIT team's strategy ""provides a rich new source of evidence on this highly dynamic process,"" says Nikolaus Kriegeskorte, a principal investigator in cognition and brain sciences at Cambridge University. ""The combination of MEG and fMRI in humans is no surrogate for invasive animal studies with techniques that simultaneously have high spatial and temporal precision, but Cichy et al.","The right panel illustrates the structure in the MEG decoding matrix at peak latency revealed by the first two dimensions of the MDS (criterion: metric stress, 0.24 for a-c,e, 0.27 for d). acc."" indicates decoding accuracy.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.nicl.2013.09.001,Psychology_easy_209,"""This research is one of the first real applications of 'Big Data' analytics, taking medical information from large numbers of patients, removing anything that would identify specific individuals, and then bringing the data into the 'cloud' to allow very high-powered analysis,"" Lewin said.",42 B preclinical (n = 20) 19.4 ± 19.2 1.2 ± 1.2 9.5 ± 20.6 0.3 ± 0.8 10.6 ± 14.4 2.7 ± 3.1 .023 ± 0.039 1.04 ± 1.73 B ApoE4+ (n = 44) 9.7 ± 29.4 0.6 ± 2.0 16.9 ± 25.1 0.7 ± 0.9 6.6 ± 16.2 1.3 ± 3.4 .016 ± 0.034 0.71 ± 1.48 B ApoE4− (n = 73) 12.5 ± 30.0 0.7 ± 1.9 13.2 ± 20.7 0.5 ± 0.8 4.7 ± 15.9 0.6 ± 5.5 .002 ± 0.042 0.01 ± 2.47,"Finally, he added, the data acquisition is free of ionizing radiation, allowing doctors to study the most vulnerable, youngest patients and perhaps to help initiate disease-specific treatment before irreversible injury to the developing brain occurs. ""This research is one of the first real applications of 'Big Data' analytics, taking medical information from large numbers of patients, removing anything that would identify specific individuals, and then bringing the data into the 'cloud' to allow very high-powered analysis,"" Lewin said. ""This has been a goal of the medical community for almost a decade, and professors Miller and Mori have found a way to implement this technology in a manner that can bring its benefit to our patients, and can assist in the classification and identification of rare and subtle brain disorders as well as uncommon manifestations of more common diseases of the brain.""","16.7 ± 37.1 1.0 ± 2.4 14.5 ± 30.4 0.9 ± 2.3 4.3 ± 17.3 0.6 ± 4.7 .001 ± 0.040 −0.03 ± 2.18 B controls (n = 81) 9.4 ± 27.6 0.6 ± 1.8 17.6 ± 22.4 0.7 ± 0.9 5.2 ± 14.8 1.0 ± 3.3 .008 ± 0.031 0.33 ± 1. 42 B preclinical (n = 20) 19.4 ± 19.2 1.2 ± 1.2 9.5 ± 20.6 0.3 ± 0.8 10.6 ± 14.4 2.7 ± 3.1 .023 ± 0.039 1.04 ± 1.73 B ApoE4+ (n = 44) 9.7 ± 29.4 0.6 ± 2.0 16.9 ± 25.1 0.7 ± 0.9 6.6 ± 16.2 1.3 ± 3.4 .016 ± 0.034 0.71 ± 1.48 B ApoE4− (n = 73) 12.5 ± 30.0 0.7 ± 1.9 13.2 ± 20.7 0.5 ± 0.8 4.7 ± 15.9 0.6 ± 5.5 .002 ± 0.042 0.01 ± 2.47 The transformation whose Jacobian is shown is a diffeomorphism between a template centered to the control group, and a template centered to the preclinical group.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1016/j.jarmac.2014.03.005,Psychology_easy_210,"The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created.",[82],"""High cognitive ability may allow individuals to overcome the biasing effect of political orientation and more effectively monitor the sources of their memories,"" the authors note. The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created. Devising strategies to prevent false voter memories may require implementing more sophisticated measures, perhaps in addition to issuing warnings about misinformation.",as if they had been obtained in a between-participants design) is perhaps slightly optimistic. [82] effectively halving the weights for those effects sizes.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1016/j.jalz.2018.06.2856,Psychology_easy_211,"Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions.",3.,"""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions. Cataract diagnosis was not an Alzheimer's disease risk factor.","However, cataract diagnosis was not associated with AD. 3. Future directions: Caregivers and health-care workers should facilitate adequate ophthalmic care for older individuals at risk of dementia.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1016/j.nicl.2013.09.001,Psychology_easy_213,"""This research is one of the first real applications of 'Big Data' analytics, taking medical information from large numbers of patients, removing anything that would identify specific individuals, and then bringing the data into the 'cloud' to allow very high-powered analysis,"" Lewin said.","The bottom panel shows only the vertices on the surfaces of the templates which are statistically significant for atrophy as measured by the permutation testing, demonstrating statistically significant change for the controls versus the preclinical AD cases based on family wise error rates FWER = 5%.","Finally, he added, the data acquisition is free of ionizing radiation, allowing doctors to study the most vulnerable, youngest patients and perhaps to help initiate disease-specific treatment before irreversible injury to the developing brain occurs. ""This research is one of the first real applications of 'Big Data' analytics, taking medical information from large numbers of patients, removing anything that would identify specific individuals, and then bringing the data into the 'cloud' to allow very high-powered analysis,"" Lewin said. ""This has been a goal of the medical community for almost a decade, and professors Miller and Mori have found a way to implement this technology in a manner that can bring its benefit to our patients, and can assist in the classification and identification of rare and subtle brain disorders as well as uncommon manifestations of more common diseases of the brain.""","The range of volume decrease as measured by the Jacobian is 0.8 to 1. The bottom panel shows only the vertices on the surfaces of the templates which are statistically significant for atrophy as measured by the permutation testing, demonstrating statistically significant change for the controls versus the preclinical AD cases based on family wise error rates FWER = 5%. Non-significant vertices have zero intensity.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1038/s41598-017-03627-7,Psychology_easy_214,The authors hope it can inform the discussion as health care providers seek opioid-free pain relief options.,"Specifically, high women's analgesia as opposed to low analgesia was related to increased coupling between female velocity and male acceleration (Δζ t(p) = 0.015, p < 0.001, 95% CI [0.008, 0.022]) and greater association between male velocity and female acceleration (Δζ t(p) = 0.019, p < 0.001, 95% CI [0.010, 0.028]) in the touch condition.","When leaders and followers or therapists and clients have a good rapport, their brainwaves fall into a similar pattern. The authors hope it can inform the discussion as health care providers seek opioid-free pain relief options. I reached for her hand and it seemed to help,"" he recalls.","As in the case of respiration fluctuations, women's analgesia and touch significantly moderated the effect of cross-partner velocity for heart rate (F (4,13000) = 5.03, p < 0.0001, ΔBIC = −267895.6, ΔR 2 = 0.25). Specifically, high women's analgesia as opposed to low analgesia was related to increased coupling between female velocity and male acceleration (Δζ t(p) = 0.015, p < 0.001, 95% CI [0.008, 0.022]) and greater association between male velocity and female acceleration (Δζ t(p) = 0.019, p < 0.001, 95% CI [0.010, 0.028]) in the touch condition. However, these contrasts were not significant in the no-touch conditions (Δζ nt(p) = 0.003, p = 0.67, males), (Δζ nt(p) = 0.022, p = 0.17, females).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1016/j.jarmac.2014.03.005,Psychology_easy_216,"It's a problem that psychological scientists may be uniquely qualified to work on.""",1 and 2 were identical except for the absence (Exp.,"""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events. It's a problem that psychological scientists may be uniquely qualified to work on.""","actually reported (in the co-witness discussion or in the written witness report) and differed slightly across groups (means ranging from 1.48 to 1.69); the reported number is a rough average. 1 and 2 were identical except for the absence (Exp. Only Exp.1 contained a post-warning condition, all other experiments in used pre-warnings.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.3402/ejpt.v5.22250,Psychology_easy_217,"Finally, one of the people in my head started to actually talk to me and said they were just there to keep us safe.",TestÁretest reliability has been reported to range from 0.79 to 0.96 and split-half reliability as 0.83 () .,"It wasnat until 8th grade when I talked to someone else about what I was experiencing did I realize most people donat live life like this. Finally, one of the people in my head started to actually talk to me and said they were just there to keep us safe. I was in denial for quite a bit after the diagnosis, but when I finally came out of it I was able to get to know my system and begin healing.a

Joubert says that navigating the healing process in a culture that continues to stigmatize DID has been challenging.",Van IJzendoorn and Schuengel (1996) reported that the mean alpha reliability of the DES in their meta-analysis was 0.93. TestÁretest reliability has been reported to range from 0.79 to 0.96 and split-half reliability as 0.83 () . It distinguishes between interpersonal trauma inflicted by someone with whom the victim was close to (betrayal trauma) and the same trauma committed by not-close perpetrators.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1080/08870446.2013.818674,Psychology_easy_218,"Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain.","Most participants were currently employed (n=86, 81.1%) and reported having attended nine years of schooling (n= 75, 70.8%).","Self-efficacy and support

The result: support from their partners is helpful to smokers who wish to stop and it increases their chances of success, provided that they have developed skills of their own that help them to abstain. Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations. Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette).","In large parts, participants had children (n=62, 58.5%). Most participants were currently employed (n=86, 81.1%) and reported having attended nine years of schooling (n= 75, 70.8%). Overall, participants had a strong intention to quit smoking (see Table 1 ).",[1],Psychology,train,1.0,news,http://www.healthcanal.com/substance-abuse/41119-rauchstopp-zu-zweit.html
10.1093/jcr/ucw012,Psychology_easy_219,"One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious.","Both types of preferences provide useful information for marketers , but revealed preferences are generally more reliable in predicting future behavior .","People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet. One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious. By the time it dropped below 30%, she was ""not having fun anymore.""","Revealed preferences are ""revealed"" by observing actual choice (vs. simply asking consumers to state their preferences). Both types of preferences provide useful information for marketers , but revealed preferences are generally more reliable in predicting future behavior . The notion of revealed preferences parallels that of constructed preferences, which are constructed on the fly as a result of the interaction between the (internal) properties of the human decision making system and the (external) properties of the environment in which a decision is made .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdev.12250,Psychology_easy_220,"In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.",3.,"By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","This constellation will be linked to greater peer popularity in the short term, but this link will fade as adolescence progresses and peers mature. 3. Early adolescents engaging in high levels of pseudomature behavior will continue to be preoccupied with social status in new social venues (i.e., romantic relationships) as development progresses into early adulthood.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1038/s41598-017-03627-7,Psychology_easy_221,"For now, it's worth a try.","Although the current study used a controlled design with several balanced conditions, it has several limitations that need to be acknowledged.","According to Goldstein, ""it's unlikely that this research will solve the problem of painkillers."" For now, it's worth a try. Depending on what ails you, you may want to reach for your honey's hand to hold.","It is thus possible that males did not realize the magnitude of the effectiveness of their touch and therefore their pain ratings did not decrease in the touch condition. Although the current study used a controlled design with several balanced conditions, it has several limitations that need to be acknowledged. First, only the female participants underwent pain stimuli while the male participants did not, so that the generalizability of our results is restricted to the male-to-female direction.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1177/0963662516629749,Psychology_easy_222,"However, none of that fascinating footage made the final cut.","One respondent described the public as ""the sum of us,"" while another identified the public as ""myself, my neighbors, the people in my community.""","This is a very significant departure - and one which is arguably long overdue. However, none of that fascinating footage made the final cut. This was already happening in 2015.","Comments in this area did not make judgments or present valenced feelings about the public. One respondent described the public as ""the sum of us,"" while another identified the public as ""myself, my neighbors, the people in my community."" Although these participants may not have explicitly made positive judgments of the public, the fact that they consider themselves a part of this collective suggests they see similarities with people who may be very different from them professionally.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.1007/s13524-014-0321-x,Psychology_easy_225,"O numero otimo de filhos depende entao da idade, da epoca da vida e das condicoes da familia.",This theoretical framework is useful for demographers in understanding how the subjective experience of the transition to parenthood can affect parity progression Fig.,"Quando se da o contrario e a familia nao tem os apoios financeiros, sociais ou emocionais necessarios, talvez o melhor seja manter a familia mais pequena. O numero otimo de filhos depende entao da idade, da epoca da vida e das condicoes da familia. Acompanhe o site eleito pelo terceiro ano consecutivo Escolha do Consumidor e Premio Cinco Estrelas 2019 para Imprensa Online.",The experience of having a first child may affect new parents' decisions about whether to have another child. This theoretical framework is useful for demographers in understanding how the subjective experience of the transition to parenthood can affect parity progression Fig. Standard errors are estimated using robust methods that account for the clustering of data within individuals.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1111/cdev.12250,Psychology_easy_226,"Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study.",**p < .01.,"""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said. Teens who become popular simply by hanging out with pretty people probably don't work as hard to develop meaningful relationships, according to the study. One thing to note is that this was a relatively small study.",".20** .20** Statistics for step .035** .070* *p < .05. **p < .01. ***p < .001. close friendship competence in early adolescence, higher levels of pseudomature behavior at ages 13-15 predicted lower peer ratings of participants' close friendship competence in early adulthood.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1038/nn.3635,Psychology_easy_227,come closer to characterizing the dynamic emergence of representational geometries across stages of processing in humans than any previous work.,MDS at the 136-ms peak (Fig.,"""The combination of MEG and fMRI in humans is no surrogate for invasive animal studies with techniques that simultaneously have high spatial and temporal precision, but Cichy et al. come closer to characterizing the dynamic emergence of representational geometries across stages of processing in humans than any previous work. The approach will be useful for future studies elucidating other perceptual and cognitive processes,"" says Kriegeskorte, who was not part of the research team.","Indeed, we found that the distinction between faces and bodies was significant at 56 ms (46-74 ms), with a clear peak at 136 ms (131-140 ms) ( Fig. MDS at the 136-ms peak (Fig. 2c ) showed a division between faces and bodies, dominated by nonhuman bodies versus the other conditions.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/01/140127141758.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s13524-014-0321-x,Psychology_easy_229,Acompanhe o site eleito pelo terceiro ano consecutivo Escolha do Consumidor e Premio Cinco Estrelas 2019 para Imprensa Online.,Tests for overall male-female difference are significant at p < .05 (SOEP) and p < .01 (BHPS).,"Quando se da o contrario e a familia nao tem os apoios financeiros, sociais ou emocionais necessarios, talvez o melhor seja manter a familia mais pequena. O numero otimo de filhos depende entao da idade, da epoca da vida e das condicoes da familia. Acompanhe o site eleito pelo terceiro ano consecutivo Escolha do Consumidor e Premio Cinco Estrelas 2019 para Imprensa Online.","Standard errors are estimated using robust methods that account for the clustering of data within individuals. Tests for overall male-female difference are significant at p < .05 (SOEP) and p < .01 (BHPS). Significance markers under the x-axis are for the test between men and women and are as follows: † p < .10; *p < .05; **p < .01; ***p < .001 over the course of parenthood (joint test for the difference in coefficients from 1-2 years to 10-15 years after birth, p < .05).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1002/eat.20625,Psychology_easy_230,"For new companies, laundering what are often fairly conventional diet practices through the language of technology provides the imprimatur of newness in the eyes of seasoned dieters, as well as a Trojan horse to reach consumers who, for whatever reason, were never interested in dieting qua dieting.","Of 23,134 plan members invited to participate, 3714 women and 1808 men returned a completed survey (24% participation).","The firm found that that was due to two things: the growing popularity of the size-acceptance movement, and dieter fatigue. For new companies, laundering what are often fairly conventional diet practices through the language of technology provides the imprimatur of newness in the eyes of seasoned dieters, as well as a Trojan horse to reach consumers who, for whatever reason, were never interested in dieting qua dieting. So if we're no longer dieting and instead biohacking in order to fine-tune our personal microbiome using state-of-the-art testing and results-based methodology, then the potential market broadens.","Conclusions-Few studies of eating disorders include men, yet our findings suggest that a substantial minority of men also report eating disorder symptoms. Of 23,134 plan members invited to participate, 3714 women and 1808 men returned a completed survey (24% participation). Men (mean = 27.5, SD = 5.6) and women (mean = 27.4, SD = 5.4) did not differ in age (t(5520) < 1, p = .54), race (88.3% and 88.9% white, χ 2 (1) < 1, p = .54), ethnicity (6.5% and 6.7% Hispanic, χ 2 (1) < 1, p = .75), or marital status (61.3% and 62.9% married/partnered, χ 2 (1) = 1.40, p = .24).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37544034795&p=1pl&v=1&x=nSrZYazEZSBbGoNGR6w7Vg
10.1038/s41598-017-03627-7,Psychology_easy_231,"The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting.","As a result they probably experienced higher levels of pain and distress during the pain condition, which may disrupt the physiological coupling.","That sounds so nice. The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting. ""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands.""","However, one should take into account major differences between this study and the current study. As a result they probably experienced higher levels of pain and distress during the pain condition, which may disrupt the physiological coupling. In addition, a possible explanation for these contradictory findings may rely on the different definitions of synchronization used in the two studies.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1038/s41598-017-03627-7,Psychology_easy_232,"For now, it's worth a try.","However, there was no difference between pain and no pain during both touch (Δζ t(p/np) = 0.004, p = 0.115) and no touch (Δζ nt(p/np) = 0.002, p = 0.637) conditions.","According to Goldstein, ""it's unlikely that this research will solve the problem of painkillers."" For now, it's worth a try. Depending on what ails you, you may want to reach for your honey's hand to hold.","In line with our hypotheses, the coupling during touch increased compared to during no touch in both the no pain (Δζ t/nt(np) = 0.010, p < 0.001, 95% CI [0.006, 0.014]) and the pain (Δζ t/nt(p) = 0.008, p < 0.001, 95% CI [0.003, 0.012]) conditions. However, there was no difference between pain and no pain during both touch (Δζ t(p/np) = 0.004, p = 0.115) and no touch (Δζ nt(p/np) = 0.002, p = 0.637) conditions. As in the case of respiratory rate, touch and pain moderated the partners' velocity effect both in women and in men (F (4,25000) = 19.40, p < 0.0001, −ΔBIC = 7.7, ΔR 2 = 0.12), indicating that the partner velocity effect differed across experiment conditions.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1038/s41598-017-03627-7,Psychology_easy_234,"I'd spent so long with a man who resisted any attempts at hand-holding that it had never really occurred to me that I might not like it, either.","The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 .","My hand got sweaty. I'd spent so long with a man who resisted any attempts at hand-holding that it had never really occurred to me that I might not like it, either. He managed to hold on, at any rate.","Moreover, tactile-induced analgesia 66 correlates with activations in brain areas related to multimodal neural activity 67 and emotional processes . The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 . The ACC appears to play a role in a variety of autonomic functions, such as regulating heart rate and blood pressure 76 .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1007/s13524-014-0321-x,Psychology_easy_235,"No entanto, se a norma mudasse, penso que a resposta a pergunta mudaria tambem"", diz.",This theoretical framework is useful for demographers in understanding how the subjective experience of the transition to parenthood can affect parity progression Fig.,"""Por isso, talvez dois seja o ideal num sitio em que a norma e ter dois. No entanto, se a norma mudasse, penso que a resposta a pergunta mudaria tambem"", diz. ""Quando um casal sente que tem mais interesse em ter filhos; mais energia para criancas; talvez mais apoio, como os avos por perto; e um salario decente, ter uma familia grande pode ser a melhor opcao"", opina Brad Wilcox, diretor do National Marriage Project da Universidade de Virginia, nos EUA.",The experience of having a first child may affect new parents' decisions about whether to have another child. This theoretical framework is useful for demographers in understanding how the subjective experience of the transition to parenthood can affect parity progression Fig. Standard errors are estimated using robust methods that account for the clustering of data within individuals.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1177/0963662516629749,Psychology_easy_236,"However, none of that fascinating footage made the final cut.",We offer empirical evidence that demonstrates that scientists who have less positive attitudes toward the social sciences are more likely to adhere to the knowledge deficit model of science communication.,"This is a very significant departure - and one which is arguably long overdue. However, none of that fascinating footage made the final cut. This was already happening in 2015.","Second, the persistence of this model may be a product of current institutional structures. We offer empirical evidence that demonstrates that scientists who have less positive attitudes toward the social sciences are more likely to adhere to the knowledge deficit model of science communication. We find that perceiving a knowledge deficit in the public is closely tied to scientists' perceptions of the individuals who comprise the public.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.3402/ejpt.v5.22250,Psychology_easy_237,aWe had a lot of experiences with people who just didn't understand DID.,"However, a sample size of 11 does limit the number of inferential statistical tests that can meaningfully be performed.","I was in denial for quite a bit after the diagnosis, but when I finally came out of it I was able to get to know my system and begin healing.a

Joubert says that navigating the healing process in a culture that continues to stigmatize DID has been challenging. aWe had a lot of experiences with people who just didn't understand DID. We had similar experiences in the medical community and in everyday life.","However, interpretations such as these will have to wait for more data and replication before being supported. However, a sample size of 11 does limit the number of inferential statistical tests that can meaningfully be performed. The small number of participants meant that observed power was very low in many of the analyses.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1111/cdev.12250,Psychology_easy_238,"They may be cool now, but see what happens in 10 years.",Those adolescents who did not have data available from close friends in early adulthood differed from those who did have such data only in having higher initial family income.,"They may be cool now, but see what happens in 10 years. ""It appears that while so-called cool teens' behavior might have been linked to early popularity, over time, these teens needed more and more extreme behaviors to try to appear cool,"" Joseph P. Allen, lead author and professor of psychology at the University of Virginia, said in statement. At 13, those who exhibited ""pseudomature behaviors"" -- a catchall term for behaviors that seem to boost perceived popularity -- were rated as more popular by their peers.","Analyses indicated that adolescents for whom follow-up data were not available in early adulthood differed from those for whom data were available only in terms of having lower levels of popularity and higher levels of minor deviant behavior at age 15. Those adolescents who did not have data available from close friends in early adulthood differed from those who did have such data only in having higher initial family income. Because these procedures have been found to yield the least biased estimates when all available data are used for longitudinal analyses (vs. listwise deletion of missing data; , the entire original sample of 184 was utilized for these analyses.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1093/jcr/ucw012,Psychology_easy_244,"People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet.","These results therefore show that the identity prime used in the main study was successful in at least temporarily increasing interest in sophisticated activities, even though we did not observe an effect of the prime on purchase intentions in the main study.","The researchers found that most of the people they interviewed fretted about their phone's battery life and their proximity to a power source, and that this ""range anxiety"" influenced the commuters' itineraries and moods. People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet. One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious.","As expected, the sophisticated options were rated, on average, as more sophisticated than the scale midpoint (M ¼ 5.80, t ¼ 22.3, p < .0001), whereas the unsophisticated options were rated as less sophisticated than the scale midpoint (M ¼ 2.95, t ¼ À13.13, p < .0001). These results therefore show that the identity prime used in the main study was successful in at least temporarily increasing interest in sophisticated activities, even though we did not observe an effect of the prime on purchase intentions in the main study. The results of study 2 therefore support our proposition that the effect of receiving a behaviorally targeted ad is distinct from that of successful identity salience manipulations, but they do not necessarily imply that targeted ads are more impactful under all circumstances.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdev.12250,Psychology_easy_245,"By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement.","Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information.","Meanwhile, as the young James Deans and Miley Cyruses aged they had to engage in ever-riskier behavior to keep thinking of themselves as cool. By their early twenties, they were more likely to have drug and alcohol problems, relationship issues and criminal involvement. Turns out being a cool kid has a really short shelf life.","Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence. Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information. Adolescents' parents reported a median family income in the $40,000-$59,999 range.",[1],Psychology,train,1.0,news,http://www.scientificamerican.com/podcast/episode/cool-kids-age-poorly/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29
10.1093/jcr/ucw012,Psychology_easy_250,"People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet.",The results of our studies suggest that online advertisers should adopt the AdChoices icon to disclose when an ad has been behaviorally targeted and continue to educate consumers on its meaning.,"The researchers found that most of the people they interviewed fretted about their phone's battery life and their proximity to a power source, and that this ""range anxiety"" influenced the commuters' itineraries and moods. People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet. One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious.","Our findings also have implications for managers because we find that consumer responses to behaviorally targeted ads are sensitive to several variables under managerial control. The results of our studies suggest that online advertisers should adopt the AdChoices icon to disclose when an ad has been behaviorally targeted and continue to educate consumers on its meaning. Given that behaviorally targeted ads act as implied labels only when consumers know that the ad was behaviorally targeted, the icon can prompt positive effects among consumers whose past behavior is plausibly connected to an implied label.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdev.12250,Psychology_easy_254,"""The student who was popular and was running with the fast crowd isn't doing as great later on.""",Two of the three behaviors in the pseudomature cluster examined in this study were not even considered deviant.,"Worse yet, findings revealed that many were also more likely to encounter issues with substance abuse. ""The student who was popular and was running with the fast crowd isn't doing as great later on."" By about 22, the cool group had a 45 percent higher rate of problems related to alcohol and substance abuse.","Importantly, the predictions to future problematic behaviors were not a reflection of simple continuities over time in levels of deviance. Two of the three behaviors in the pseudomature cluster examined in this study were not even considered deviant. More importantly, early adolescent pseudomature behavior had value in predicting future criminal behavior and alcohol and marijuana use problems over and above early adolescent markers of such problems.",[1],Psychology,train,1.0,news,http://www.scienceworldreport.com/articles/15380/20140612/treatment-of-sleep-apnea-helps-improve-heart-health.htm
10.1176/appi.ajp.2018.17111282,Psychology_easy_255,"But even though products promising a future filled with personalized medicine are starting to hit drugstore shelves, the research still suggests we're not at a point where our genes can help determine our dosages -- yet.",Additional data from well-controlled randomized controlled trials are needed to understand the clinical utility of the IDgenetix neuropsychiatric test panel.,"It's simply too early. Ultimately, we're all interested in making medication more efficient. But even though products promising a future filled with personalized medicine are starting to hit drugstore shelves, the research still suggests we're not at a point where our genes can help determine our dosages -- yet.","Tolerability may have been improved by IDgenetix testing, because significantly fewer subjects in the guidedtreatment group reported adverse drug events (28% compared with 53%; p50.001). Additional data from well-controlled randomized controlled trials are needed to understand the clinical utility of the IDgenetix neuropsychiatric test panel. No significant differences in the average duration of major depression or number of episodes between patients assigned to the guided treatment and treatment-as-usual comparator arms were found, although past treatment history was not reported.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1093/jcr/ucw012,Psychology_easy_256,"People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet.",Simple effects analyses using three levels of a priori interest in outdoors-related products confirmed this pattern (figure 4).,"The researchers found that most of the people they interviewed fretted about their phone's battery life and their proximity to a power source, and that this ""range anxiety"" influenced the commuters' itineraries and moods. People chose their next destination -- the gym, the coffee shop, the market -- in part based on whether they would have easy access to a charging outlet. One 23-year-old told the researchers that when her phone's battery life fell to 50%, she began to feel anxious.","Floodlight analysis using the Johnson-Neyman technique revealed a significant positive effect of behavioral targeting on participants' self-perceptions of outdoorsiness only among participants who made four through nine outdoors-related choices in the shopping task (i.e., at moderate and high levels of accuracy; B JN ¼ .28, SE ¼ .14, p ¼ .05). Simple effects analyses using three levels of a priori interest in outdoors-related products confirmed this pattern (figure 4). The lack of significance at the top of the scale (i.e., 10 of 10 choices) likely reflects either a ceiling effect (due to the fact that participants who made 10 outdoors-related choices already perceive themselves as so outdoorsy that there is no room for movement as a result of an implied social label) or a lack of power (as only seven people made 10 outdoors-related choices: M behavioral ¼ 6.80, M nontargeted ¼ 7.00; F(1, 5) ¼ .36, p ¼ .58).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jpeds.2017.10.028,Psychology_easy_257,The other evidence-based approach he recommends is taking something positive away.,"Indeed, the origins and outcomes of dating violence are complex, as demonstrated by the vast heterogeneity of factors explaining violence within the context of an intimate relationship.","As a father himself, he knows this is difficult to adhere to, but he believes this can happen even in the most difficult situation. The other evidence-based approach he recommends is taking something positive away. All of this is in service of teaching children to be respectful without disrupting the vital positive elements of the caretaker-child relationship.","The finding that childhood corporal punishment was linked to perpetration of dating violence even after controlling for covariates underscores the importance of corporal punishment when considering partner violence etiology. Indeed, the origins and outcomes of dating violence are complex, as demonstrated by the vast heterogeneity of factors explaining violence within the context of an intimate relationship. Social modeling may be particularly toxic when the child admires the perpetrator, and perceives the individual as competent and of high social status.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1111/cdev.12250,Psychology_easy_258,"These numbers are not an exact match to the general American population, but they're not far off either.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior.","The average family range of annual income was $40,000 to $59,999 and about 58% of the subjects described themselves as Caucasian, 29% as African-American, 8% as mixed race and ethnicity, and 5% as being from other minority groups. These numbers are not an exact match to the general American population, but they're not far off either. According to the US Census Bureau, in 2013 about 77% of the population identified as Caucasian, 13% as African-American, 2.4% as ""two or more races,"" and the rest included other categories like ""Asian,"" ""Native Hawaiian,"" ""Hispanic,"" etc.","Longitudinal results, however, supported the study's central hypothesis: Early adolescent pseudomature behavior predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior. In contrast, teens can also gain the appearance of maturity in more benign, if still immature, ways. Each of these behaviorsminor deviance, a focus on physical appearance in choosing friends, and precocious romantic activityis clearly distinct, yet each shares in common the potential to provide a veneer of maturity to the early adolescent seeking to enhance status with his or her peers.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1038/s41598-017-03627-7,Psychology_easy_259,My hand got sweaty.,"In contrast to our original hypothesis, pain did not increase physiological coupling in the absence of the partner's touch.","Almost immediately, I was acutely aware of all the two-handed things I could no longer do: fix my ponytail, uncap the water bottle in my purse. My hand got sweaty. I'd spent so long with a man who resisted any attempts at hand-holding that it had never really occurred to me that I might not like it, either.","Thus, it could be suggested that inter-personal physiological coupling underlie touch-related analgesia. In contrast to our original hypothesis, pain did not increase physiological coupling in the absence of the partner's touch. This effect was consistent across both physiological signals and for both model directions (female-male, male-female).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1038/s41598-017-03627-7,Psychology_easy_260,"I want it in the same way that I want to be a person who likes watching sports, or finds George Clooney attractive, because both seem to be experiences that have brought a lot of joy to a lot of people.",These findings of physiological coupling may also explain recent findings of partners being able to influence women during labor.,"But arriving here made me oddly sad, the kind of sadness that comes with realizing that something you like about yourself isn't really true. I want it in the same way that I want to be a person who likes watching sports, or finds George Clooney attractive, because both seem to be experiences that have brought a lot of joy to a lot of people. And it's lonely being on the outside, especially when the experience in question is such a quietly lovely one.","However, in this study, both directions showed the same pattern of results supporting the idea of physiological bi-directional communication. These findings of physiological coupling may also explain recent findings of partners being able to influence women during labor. Apparently, skin to skin touch is important for pain reduction, which may explain people's preference for social touch 58 .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.3402/ejpt.v5.22250,Psychology_easy_261,aI would say one very popular misconception is that people with DID donat know they have it or donat know anything about their alters.,The IM is the first standardized measure of integration in DID.,"We are also tired of the 'evil alter' trope that is portrayed time and time again in media.a

I fully believe I would not be here today if it wasn't for my system. aI would say one very popular misconception is that people with DID donat know they have it or donat know anything about their alters. For some people, especially people who have not yet been diagnosed or started therapy, this is true,a Joubert says.","The IM is the first standardized measure of integration in DID. Results: Participants switched among identities an average of 5.8 times during the first session, and switching was highly correlated with trauma. Integration was related to switching, though this relationship may be nonlinear.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1111/cdev.12250,Psychology_easy_263,"""Doing so by pretending to be someone you aren't doesn't work so well in the long run.""","In addition, the sociometric assessment employed in this study limited raters to those from the same grade level (as do virtually all such assessments).","None of this is necessarily new information, not to parents at least, but Joseph Allen, the leader of the new study, believes learning how teenagers come to manifest certain behaviors and express them over a long timeline, is helpful for teaching kids a safer way to be cool. ""Doing so by pretending to be someone you aren't doesn't work so well in the long run."" In fact, it's pretty awful.","Similarly, the measure of valuing popularity, relying solely upon lay usage of the term, did not clearly distinguish between social preference versus social status in peer relationships. In addition, the sociometric assessment employed in this study limited raters to those from the same grade level (as do virtually all such assessments). In this case, however, the result is that if teens succeed in achieving popularity among older adolescents (but not among their age mates), our assessment would not have detected this effect.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1080/09500693.2018.1540897,Psychology_easy_265,Big challenges lie ahead.,"However, because these outcomes are perceptions of changes, they cannot provide evidence for actual changes in interest or persistence in STEM due to the programme.","We need to do better a not just for equalityas sake, but for scienceas sake."" Big challenges lie ahead. However, with some serious institutional work, things could improve a and the Report Card of the future could look far more glowing.","Case studies (observations, interviews) can provide very useful in-depth information about how the programme is experienced by students, their behaviour during the programme or their perception of the influence of the programme on their future educational (career). However, because these outcomes are perceptions of changes, they cannot provide evidence for actual changes in interest or persistence in STEM due to the programme. Therefore, such case studies or mixed method studies with a pre/post-test design were classified as 'weak causal evidence' as well.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1016/j.nicl.2013.09.001,Psychology_easy_266,"""If a diagnosis is already attached to an image from the data bank, that could steer the physician in the right direction.",This permutation testing procedure also provides a (conservative) estimate of the set of vertices v on which the null hypothesis is not valid.,"The new pediatric brain imaging data bank, Miller said, will be useful in at least two ways. ""If a diagnosis is already attached to an image from the data bank, that could steer the physician in the right direction. Also, the scans in our library may help a physician identify a change in the shape of a brain structure that occurs very early in the course of a disease, even before clinical symptoms appear.","The volume statistics shown in column 4 of Table 5 for the three groups provides p-values for the same linear effects model, also evaluated via permutations, in which y is replaced by the structure volume, for which no multiple testing correction is required. This permutation testing procedure also provides a (conservative) estimate of the set of vertices v on which the null hypothesis is not valid. Table 3 shows the rates of atrophy for linear fits of the amygdala, hippocampus and entorhinal cortex volumes as a function of scan number for the controls and the preclinical AD subjects.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1080/09500693.2018.1540897,Psychology_easy_267,Conferences with a higher proportion of female speakers are also a good way to help.,"These cultural differences should also be taken into account in reviewing the interventions, while some interventions can be effective in one context and have no effect in others.","""There are several interventions that institutions might consider to promote gender equality, including a strict and transparent policy for gender harassment; promoting a culture of respect; formal mentorship and sponsorship programming; and supportive, flexible policies for both birthing and non-birthing parents as they return to work,"" says Dr. Beeler. Conferences with a higher proportion of female speakers are also a good way to help. ""There is no doubt that we a institutions, scientists, patients, all of us a will have better outcomes and faster progress with full participation in science.""","Cultural and societal beliefs, policy and economical and work-related developments should also be considered as an influence on students' behaviour. These cultural differences should also be taken into account in reviewing the interventions, while some interventions can be effective in one context and have no effect in others. In the meta-reviews, empirical support was found for the assumption that the curriculum in STEM courses is particularly focused on 'masculine' subjects and is therefore less appealing to female students .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1073/pnas.1505114112,Psychology_easy_268,"Certain regions mature faster than others, with the ones responsible for the most basic processes, such as processing information and motor control, going first.","differentiate speech sounds to a greater extent , track stimulus pitch more accurately , and are more consistent across trials .","Despite losing neurons, however, the brain is becoming more efficient. Certain regions mature faster than others, with the ones responsible for the most basic processes, such as processing information and motor control, going first. It's for these reasons that musical training improves teens' development.","These enhancements extend to the subcortical auditory system, with musicians showing responses to sound that are faster , are degraded less by background noise , represent speech formant structure more robustly . differentiate speech sounds to a greater extent , track stimulus pitch more accurately , and are more consistent across trials . Subcortical response consistency peaks in childhood, waning into young adulthood (24), coinciding with a period when learning a second language becomes more difficult than earlier in life .",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/taking-music-class-high-school-improves-teen-language-skills-may-boost-academic-344674
10.1111/cdev.12250,Psychology_easy_269,"""Doing so by pretending to be someone you aren't doesn't work so well in the long run.""","This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","None of this is necessarily new information, not to parents at least, but Joseph Allen, the leader of the new study, believes learning how teenagers come to manifest certain behaviors and express them over a long timeline, is helpful for teaching kids a safer way to be cool. ""Doing so by pretending to be someone you aren't doesn't work so well in the long run."" In fact, it's pretty awful.","One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time. Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/cool-kids-grow-be-adult-burnouts-how-early-popularity-can-kill-childs-future-287922
10.1093/chemse/bjt066,Psychology_easy_270,"However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive.","Friedman test revealed a significant difference between the edibility ratings (χ 2 [7, n = 43] = 168.80, P < 0.001).","This finding indicates that the perceived edibility of an odour can be manipulated by a description, and that olfactory perception may be driven by a top-down (or directive) cognitive process. However, only the parmesan cheese odour elicited a different reaction time, which was slower when the label was positive. ""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu.","Furthermore, there was no significant difference between the label fit of the positive labels (M = 6.66, SD = 1.00) compared with the one of the negative labels (M = 6.66, SD = 1.54; t[9] = 0.00, P < 0.05). Friedman test revealed a significant difference between the edibility ratings (χ 2 [7, n = 43] = 168.80, P < 0.001). Edibility was rated significantly lower for odors presented with negative labels (Md = 1.42) compared with those presented with positive labels (Md = 3.96).",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jalz.2018.06.2856,Psychology_easy_271,"The results offer physicians a new way to detect those at higher risk of this disorder, which causes memory loss and other symptoms of cognitive decline.",There was no association between cataract and AD.,"The results offer physicians a new way to detect those at higher risk of this disorder, which causes memory loss and other symptoms of cognitive decline. ""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Patients with age-related macular degeneration, diabetic retinopathy, or glaucoma were at 40 % to 50% greater risk of developing Alzheimer's disease compared to similar people without these eye conditions.","We found glaucoma, AMD, and DR are associated with increased risk of AD controlling for age, sex, education, APOE genotype, and smoking in a cohort of 3877 participants followed over 31,142 person-years. There was no association between cataract and AD. Without a temporal window, 20% higher AD risk was found in participants with AMD and 44% higher AD risk in those with DR compared with those without.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1038/s41598-018-30980-y,Psychology_easy_273,"Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap.","In the current study, emotional stimuli were positively associated with nocturnal SWS.","However, when memory was tested again following overnight sleep, the change in memory accuracy was greater if the child had napped the previous day. Further, Spencer and colleagues report, greater nap slow wave activity was associated with greater memory decay during the nap. Yet nap slow wave activity also predicted greater overnight improvement in memory.","The preschool nap was beneficial to both positive and negative valenced memories despite the lack of REM sleep. In the current study, emotional stimuli were positively associated with nocturnal SWS. These results are consistent with recent reports of SWS being particularly important for emotional memory consolidation in both children and adults .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1177/0141076814565942,Psychology_easy_274,"The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency.","Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration.","That number may be so low due to overwhelming beliefs that the practice equates to genital mutilation, while stateside it may be considered more comparable to dental braces. The findings are slightly complicated by earlier work that found autism emerges in utero, which suggests circumcision could only intensify a preexisting deficiency. At any rate, the findings may hold great promise for other countries to adopt formal anesthetic protocol to avoid, or at least minimize, the pain children experience.","The observed 80-83% increase in ASD risk among 0-to 4-year-old circumcised boys is therefore unlikely to be an overestimate. Limitations with respect to the outcome variables (ASD, hyperactivity disorder and asthma) also need consideration. To the extent outcomes were inaccurately or incompletely recorded in the national health registers, we might have missed some true cases, or wrongly included some irrelevant cases, as outcomes in the cohort.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/asd-and-circumcision-linked-thoughts-brain-development-factor-318144
10.1038/s41598-017-03627-7,Psychology_easy_275,This is very true.,The human capacity for generating events in synchrony 1 with other individuals has important evolutional significance.,"The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting. ""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands."" This is very true.","Furthermore, the effects of touch on cardiorespiratory inter-partner coupling may contribute to the analgesic effects of touch via the autonomic nervous system. The human capacity for generating events in synchrony 1 with other individuals has important evolutional significance. This ability develops early in life 1 12 and is crucial for social communication in general 13 and for the development of infant and mother bonding in particular 14 .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1111/cdev.12250,Psychology_easy_278,"The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence.""","Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information.","By the time these ""cool"" kids turned 23, many of them were having problems with criminal behavior and alcohol and marijuana use -- significantly more than the other subjects in the study, who were not ranked in the ""cool"" category at the study's onset. The researchers conclude with this scary notion:

""The findings support the proposition that early adolescent attempts to gain status via pseudomature behavior are not simply passing annoyances of this developmental stage, but rather may signal movement down a problematic pathway and away from progress toward real psychosocial competence."" In other words, if you're acting extreme to look cool, chances are good that you might be the only one who thinks so.","Early adolescent pseudomature behavior will predict lower levels of competence with peers in early adulthood, even after accounting for baseline levels of peer competence. Of all students eligible for participation, 63% agreed to participate either as target participants or as peers providing collateral information. Adolescents' parents reported a median family income in the $40,000-$59,999 range.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/kids-who-were-cool-at-13-are-not-at-age-23-2015-7
10.1016/j.nicl.2015.02.009,Psychology_easy_279,They also closely match the results in animal studies performed by the team and scientists elsewhere.,"In addition to areas of task related activity in the DG/CA3, analyses of the functional imaging data also revealed an area of reduced task related activity in the left entorhinal cortex (EC) in both the 62.5 mg BID cohort and the 125 mg BID cohort.","The findings validate the Johns Hopkins team's initial conclusions, published three years ago in the journal Neuron. They also closely match the results in animal studies performed by the team and scientists elsewhere. ""What we've shown is that very low doses of the atypical antiepileptic levetiracetam reduces this over-activity,"" Gallagher said.","Levetiracetam treatment with 250 mg BID, in contrast, showed no evidence of reducing activation (t = 0.1773, p = 0.8615). In addition to areas of task related activity in the DG/CA3, analyses of the functional imaging data also revealed an area of reduced task related activity in the left entorhinal cortex (EC) in both the 62.5 mg BID cohort and the 125 mg BID cohort. In the left entorhinal cortex, participants with aMCI on placebo showed significantly decreased BOLD activation during those same lure trials compared to control subjects (62.5 mg BID, t = 3.443, p = 0.002 and 125 mg BID, t = 3.278, p = 0.003).",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311124200.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1176/appi.ajp.2018.17111282,Psychology_easy_280,"But even though products promising a future filled with personalized medicine are starting to hit drugstore shelves, the research still suggests we're not at a point where our genes can help determine our dosages -- yet.","Repeated-measures analysis of change in clinical scores over time revealed a significantly greater reduction of symptoms in the GeneSight-guided treatment group than in the treatment-as-usual group after 8 weeks (on the QIDS-C, p,0.001; on the HAM-D, p,0.001; on the Patient Health Questionnaire, p,0.002).","It's simply too early. Ultimately, we're all interested in making medication more efficient. But even though products promising a future filled with personalized medicine are starting to hit drugstore shelves, the research still suggests we're not at a point where our genes can help determine our dosages -- yet.","However, the short duration of the study, the lack of blinding to mitigate placebo effects, and the modest size of the cohort (N=51) are important limitations. Repeated-measures analysis of change in clinical scores over time revealed a significantly greater reduction of symptoms in the GeneSight-guided treatment group than in the treatment-as-usual group after 8 weeks (on the QIDS-C, p,0.001; on the HAM-D, p,0.001; on the Patient Health Questionnaire, p,0.002). Furthermore, there were significant group differences in the proportion of participants meeting criteria for categorical response (44.4% of the GeneSightguided group, compared with 23.7% the treatment-as-usual group; response was defined as a reduction $50% in QIDS-C score from baseline to endpoint) and remission (26.4% of the guided group, compared with 12.9% of the treatment-as-usual group) at 8 weeks (p=0.03).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1111/cdev.12250,Psychology_easy_285,"As the years went on, however, these antics did not correlate to an increase in popularity.","Yet, if reliance upon pseudomature behavior in early adolescence diverts energy from more adaptive socialdevelopmental pursuits and leads down a path to more serious difficulties in future functioning, then even these seemingly minor behaviors may warrant significant concern as markers of long-term risk.","The cooler kids impressed their peers through displays of romantic behavior (like kissing or touching), deviant acts (like damaging their parents' property or sneaking into a movie theater without a ticket), or by associating themselves with more physically attractive friends. As the years went on, however, these antics did not correlate to an increase in popularity. In fact, just the opposite happened.","From this perspective, early adolescent pseudomature behavior may engender a long-term propensity to attain social status via less adaptive means, with consequences extending from difficulties managing peer relationships adaptively to serious deviant behavior. Yet, if reliance upon pseudomature behavior in early adolescence diverts energy from more adaptive socialdevelopmental pursuits and leads down a path to more serious difficulties in future functioning, then even these seemingly minor behaviors may warrant significant concern as markers of long-term risk. In essence, pseudomature behavior may not simply predict future problems, but may also predict the development of more serious adjustment problems over long periods of time, even after accounting for baseline levels of adjustment and problematic behavior in early adolescence.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1111/cdev.12250,Psychology_easy_286,"By 22, the cool kids struggled to make friends.","Future research might profitably examine other, more direct indices of such a focus on appearance in either one's peers or in oneself, to more precisely examine the importance of a focus on appearance in pseudomature efforts to impress peers.","If the trend lines continued past age 15, you'd expect so-called cool-kid behavior to be less associated with popularity as people get older -- and that's exactly what happened. By 22, the cool kids struggled to make friends. ""These previously cool teens appeared less competent -- socially and otherwise -- than their less cool peers by the time they reached young adulthood,"" Allen said.","Further research could clearly benefit from efforts to clarify the role of each of these aspects of peer status, and its pursuit, in pseudomature behavior. Future research might profitably examine other, more direct indices of such a focus on appearance in either one's peers or in oneself, to more precisely examine the importance of a focus on appearance in pseudomature efforts to impress peers. Finally, future research is also now clearly needed to explore potential pathways that might explain both how and why pseudomature behavior in adolescence develops, as well as the intervening mechanisms by which it leads to long-term problematic continuities.",[1],Psychology,train,1.0,news,http://www.businessinsider.com/being-popular-in-high-school-leads-to-problems-in-adulthood-2014-6
10.1136/bmjsem-2017-000261,Psychology_easy_287,"While we donat know exactly how the alerts matched up with the spikes in heart rate, itas fair to assume that the stress of the game generally stimulated the sympathetic nervous systems of the fans.","However, we identified large heterogeneity between effect sizes from individual studies where our analysis of moderating variables (eg, gender, type of sport) could not fully explain this large heterogeneity.","Some of those fans took their data to Twitter, showing what a bit of sports-driven adrenaline can do. While we donat know exactly how the alerts matched up with the spikes in heart rate, itas fair to assume that the stress of the game generally stimulated the sympathetic nervous systems of the fans. It might have done so by triggering an anticipatory feeling of stress, brought on by the memory of games past.","These findings further support the presence of anticipatory stress response in athletes before sport competition. However, we identified large heterogeneity between effect sizes from individual studies where our analysis of moderating variables (eg, gender, type of sport) could not fully explain this large heterogeneity. Hanton et al identified a significant increase in cognitive and somatic anxiety in the time leading up to competition.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34474732617&p=1pl&v=1&x=pcdQFFmMveKF7UrJyJtzvg
10.1073/pnas.1702671114,Psychology_easy_288,"When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization.",One example of the bat's sonar tracking behavior is shown in Fig.,"""...the speed at which an echolocating bat responds to ambient noise is truly shocking: 10 times faster than we blink our eyes."" When the background noise ends, the sound pressure level dissipates, and so does the level of vocalization. Even in terms of near-instantaneous brain reactions, they call this reflex ""remarkably short.""","Thus, the Lombard effect can be better described as a reflex. One example of the bat's sonar tracking behavior is shown in Fig. The high temporal resolution data provided the foundation for the model of audio-vocal volume control.",[1],Psychology,train,1.0,news,http://www.futurity.org/bats-volume-lombard-effect-1452342-2/
10.1016/j.jarmac.2014.03.005,Psychology_easy_289,"""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude.","We are not sure what this means, particularly as recognition tests are a quite heterogeneous category, comprising yes/no tests, forced-choice tests but also source monitoring tests (more fine-grained analyses -not reported in detail in our results section -did not yield a more meaningful picture, though).","Devising strategies to prevent false voter memories may require implementing more sophisticated measures, perhaps in addition to issuing warnings about misinformation. ""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events.","(1) Stronger misinformation endorsement remained after post-warnings when recall tests, as opposed to recognition tests, were used. We are not sure what this means, particularly as recognition tests are a quite heterogeneous category, comprising yes/no tests, forced-choice tests but also source monitoring tests (more fine-grained analyses -not reported in detail in our results section -did not yield a more meaningful picture, though). worked much better than other types of post-warning and completely eliminated the misinformation effect.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1093/jcr/ucw012,Psychology_easy_291,"""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""",This internal versus external distinction shares some commonality with the literature in judgment and decision making on stated versus revealed preference.,"""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them."" ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them,"" she explains.","Thus the key distinction between an advertisement making an identity salient and one that implies a social label lies in whether the information the ad provides about the self stems from a characterization that is generated internally, by the self, or from an external source. This internal versus external distinction shares some commonality with the literature in judgment and decision making on stated versus revealed preference. Revealed preferences are ""revealed"" by observing actual choice (vs. simply asking consumers to state their preferences).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1007/s13524-014-0321-x,Psychology_easy_294,The researchers also discovered that having a baby at older age is more beneficial psychologically.,"Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms.","Sociologists Mikko Myrskyla and Rachel Margolis found out that third child does not make subjective well-being greater. The researchers also discovered that having a baby at older age is more beneficial psychologically. Although many different explanations of this phenomenon were proposed, relatively little attention was paid to subjective well-being of parents.","A potentially important physiological factor may be the increased levels of the hormone oxytocin during pregnancy and after birth . Qualitative information on work-family conflict, planning status of births, and instrumental support would be useful to further our understanding of the social mechanisms. Second, social norms about childbearing have relaxed markedly over the study period, and when and how many children to have may be more of a decision than before.",[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1186/2045-5380-3-19,Psychology_easy_296,"As such, CBD can also be seen as the best alternative to Adderall for adults with ADHD.","As such, these data would suggest that eCB signaling could be compromised in stress-related affective illnesses (such as major depression or post-traumatic stress disorder, both of which appear to be driven by maladaptive responses to stressful life events), and that pharmacological enhancement of eCB signaling could be a novel therapeutic avenue for the treatment of these neuropsychiatric conditions.","And, unlike Adderall, CBD also helps ADHD sufferers deal with other mental health issues, such as anxiety disorders. As such, CBD can also be seen as the best alternative to Adderall for adults with ADHD. That said, due to the withdrawal symptoms of Adderall, those with ADHD should consult their doctor before changing their treatment.","Accordingly, impairments in eCB signaling, at either the ligand or the receptor level, would likely result in either the induction of an undue activation of stress responsive systems (such as the amygdala) under non-threatening conditions, or an impairment in appropriate stress adaptation, both of which could predispose an organism or individual to exaggerated effects of stress. As such, these data would suggest that eCB signaling could be compromised in stress-related affective illnesses (such as major depression or post-traumatic stress disorder, both of which appear to be driven by maladaptive responses to stressful life events), and that pharmacological enhancement of eCB signaling could be a novel therapeutic avenue for the treatment of these neuropsychiatric conditions. Given that there are noted pharmacokinetic, and possibly functional, differences between AEA and 2-AG , it should not be immediately assumed that inhibition of either enzyme will produce synonymous effects (although the initial studies do suggest a high degree of similarity).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1093/jcr/ucw012,Psychology_easy_297,"""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says.","This explanation for our results is consistent with our finding that behaviorally targeted ads result in higher purchase intentions for the advertised product after a one-to two-week time delay, whereas making a relevant identity temporarily salient does not.","Her study's findings imply that visual distractions -- like the ones caused by the flash of a ""new message"" alert or a news update -- might distort a person's memory of an event or interaction without that person realizing it. ""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","It is only when an implied social label introduces information about how an external agent views one's level of sophistication that self-perceptions change (in this case, being adjusted upward as a result of a marketer's characterization that one is sophisticated). This explanation for our results is consistent with our finding that behaviorally targeted ads result in higher purchase intentions for the advertised product after a one-to two-week time delay, whereas making a relevant identity temporarily salient does not. An ANOVA revealed that participants in the sophisticated (vs. control) prime condition were more interested in the studies on sophisticated topics (M sophisticated ¼ 4.83, M control ¼ 4.41, F(1, 145) ¼ 4.27, p < .05, g 2 ¼ .03) but were equally interested in the studies on less sophisticated topics (M sophisticated ¼ 4.89, M control ¼ 4.87, F(1, 145) ¼ .01, p ¼ .91).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1001/jamapsychiatry.2018.1941,Psychology_easy_299,"They found that thereas functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions.",The correlation between the sleep quality and the mean strength of these significant functional connectivities is shown in Figure 1A (r = 0.181; P =6.,"They found that thereas functional connectivity between the areas of the brain associated with short-term memory, self, and negative emotions. Depression and sleeplessness go hand in hand.A petitefox/Flickr

aAn important part of the research was that we showed that in a population from the US, available because of the Human Connectome Project, the orbitofrontal cortex had increased functional connectivity with the other brain regions in people with depressive problems,a co-author and fellow University of Warwick professor Edmund Rolls, Ph.D. tells Inverse, referring to the large-scale effort to map the complete structural and functional neural connections within the human brain. A total of 162 functional connectivity neural links involved in the areas of the brain associated with sleep were identified from these scans.","Many significantly correlated links involved the precuneus, the anterior cingulate cortex, the lateral orbitofrontal cortex, the hippocampus and parahippocampal cortex, and some motor areas ( Figure 2 ; eFigure 2 in the Supplement). The correlation between the sleep quality and the mean strength of these significant functional connectivities is shown in Figure 1A (r = 0.181; P =6. In the correlation analysis between functional connectivity, poor sleep quality, and depressive scores, we found that the PSQI score was positively correlated with the Depressive Problems raw score (r = 0.371; P < .001; Figure 1B ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34642343077&p=1pl&v=1&x=KFiPC90kn8JgzhaUX20nIg
10.1093/jcr/ucw012,Psychology_easy_300,Some of this research hints at the memory-distorting power of brief visual distractions.,The results of our studies suggest several interesting avenues for future research.,"""Anything less than half full, however, induced feelings of profound anxiety and discomfort."" Some of this research hints at the memory-distorting power of brief visual distractions. When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color.",This suggests that sales of other related products and services may be expected to increase to the extent that they are consistent with the same label. The results of our studies suggest several interesting avenues for future research. Future research could explore other sources for implied social labels in addition to behaviorally targeted ads.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-017-18902-w,Psychology_easy_301,The volunteers who scored lower on the scale also exhibited more severe forms of autism.,"Future application of the metrics described here to larger cohorts of subjects or in longitudinal studies may provide a more precise neurodevelopmental map, by using the R-parameter as well as its rate of change.","In each case, the movement-based diagnoses corresponded to these qualitative-based assessments, which are rarely in complete agreement. The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","Our findings may potentially provide a promising direction for future ASD etiology research, as well as an extra objective guidance for future genetic and pathological neuroscience studies. Future application of the metrics described here to larger cohorts of subjects or in longitudinal studies may provide a more precise neurodevelopmental map, by using the R-parameter as well as its rate of change. This map would be a powerful added tool to study individualized neurodevelopmental process and the deviations in ASD and other NNDs.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1001/jamapsychiatry.2018.1941,Psychology_easy_304,"""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls.","Table 2 shows the 60 functional connectivity links that had associations of greatest significance with the PSQI score, including names, supporting statistics, and P values.","The researchers conclude that increased functional connectivity among these brain regions provides a neural basis for how depression is related to poor sleep quality. ""This study may also have implications for a deeper understanding of depression,"" adds professor Edmund Rolls. ""This important cross-validation with participants from the USA provides support for the theory that the lateral orbitofrontal cortex is a key brain area that might be targeted in the search for treatments for depression.""","There were 162 significant links after NBS correction. Table 2 shows the 60 functional connectivity links that had associations of greatest significance with the PSQI score, including names, supporting statistics, and P values. All are significantly positively correlated with the poor sleep quality assessment.",[1],Psychology,train,1.0,news,https://www.futurity.org/depression-sleep-problems-insomnia-1821432-2/
10.1186/2045-5380-3-19,Psychology_easy_305,"In fact, CBD is likely to be more effective at improving focus and energy levels than Adderall due to the way it helps improve memory, mood and regulate sleep.","The extent to which these findings can be used on a translational platform to understand the pathophysiology of stress-related psychiatric conditions in humans has yet to be determined, but the convergence of the preclinical and clinical findings detailed here strongly suggests that this should be a field of focused research in coming years.","CBD also works faster and better than other ways to improve focus, such as dietary changes or meditation. In fact, CBD is likely to be more effective at improving focus and energy levels than Adderall due to the way it helps improve memory, mood and regulate sleep. They are also more likely to abuse alcohol and other drugs, indicating a more widespread addiction problem in addition to Adderall abuse.","Elevated eCB signaling seems to be associated with reduced stress and anxiety, while impaired eCB signaling is associated with greater vulnerability to stress, anxiety and depression. The extent to which these findings can be used on a translational platform to understand the pathophysiology of stress-related psychiatric conditions in humans has yet to be determined, but the convergence of the preclinical and clinical findings detailed here strongly suggests that this should be a field of focused research in coming years. We propose several areas of research that would help to fill gaps in knowledge and guide research to further determine the therapeutic utility of the eCB system with respect to the development of novel therapeutics for mood and anxiety disorders.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1038/s41598-018-30980-y,Psychology_easy_306,"This delay may reflect ""short-term destabilization of an enriched memory,"" they add.","In adults, emotion processing and emotional memory are enhanced over sleep.","The researchers say another highlight of their work is finding that naps do contribute to emotion processing in preschool children, which is consistent with parents' and early childhood teachers' observations, though this benefit in emotional memory is delayed, say Spencer and colleagues. This delay may reflect ""short-term destabilization of an enriched memory,"" they add. That is, ""there may be measurable benefits in behavior, even if not in memories themselves.""","Thus, enhancing emotional learning at this young age has wide-reaching and long-lasting impact. In adults, emotion processing and emotional memory are enhanced over sleep. For example, children exhibit more frustration when faced with an unsolvable puzzle when nap deprived compared to rested.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1007/s13524-014-0321-x,Psychology_easy_307,"""Understanding how having children influences parents' subjective happiness has great potential to explain fertility behavior,"" the scientists say.",The test for the difference between partnered and nonpartnered is significant at p < .001 (SOEP) and p < .05 (BHPS).,"Although many different explanations of this phenomenon were proposed, relatively little attention was paid to subjective well-being of parents. ""Understanding how having children influences parents' subjective happiness has great potential to explain fertility behavior,"" the scientists say. The study demonstrates that not all children cause equally good emotions.",Standard errors are estimated using robust methods that account for the clustering of data within individuals. The test for the difference between partnered and nonpartnered is significant at p < .001 (SOEP) and p < .05 (BHPS). Significance markers under the x-axis are for the test between married and not married and are as follows: † p < .10; *p < .05; **p < .01; ***p < .001 Table 2 .,[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1007/s13524-014-0321-x,Psychology_easy_308,"Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness.",The period when the controls make the most difference is the time just before The test for the difference between high-and low-educated is significant at p < .05 for men and p > .10 for women.,"The happiness level of parents varied among different ages. Those aged 35 to 49 experienced the highest level of happiness, while those between age 18 and 22 reported a decline in their happiness. A first-born child brought the most happiness, no matter what age the parents were.","For both men and women, the happiness trajectories surrounding a first birth are very similar, and the differences are statistically not significant across these models. The period when the controls make the most difference is the time just before The test for the difference between high-and low-educated is significant at p < .05 for men and p > .10 for women. Significance markers under the x-axis are for the test between high and low educated and are as follows: † p < .10; *p < .05; **p < .01; ***p < .001 and after the birth, possibly because the changes in marital status are picking up the happiness of partnering, planning a future together, and the anticipation of childbearing.",[1],Psychology,train,1.0,news,http://www.hngn.com/articles/47780/20141031/births-of-first-and-second-child-bring-parents-more-happiness-than-the-third-but-why.htm
10.1093/jcr/ucw012,Psychology_easy_310,"Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice.","We do note, however, that motivated reasoning ) may also play a role in determining what label consumers believe the ad implies because consumers may be motivated to accept a more socially desirable or positive label.","When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color. Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice. ""One of the most striking things about this study was that people weren't aware they were making these big mistakes,"" says Julie Golomb, co-author of the study and an associate professor of psychology at Ohio State's Center for Cognitive and Brain Sciences.","We expect that the consumer will only accept, and subsequently exhibit behavior consistent with, the label that he or she perceives to be most connected to past behavior. We do note, however, that motivated reasoning ) may also play a role in determining what label consumers believe the ad implies because consumers may be motivated to accept a more socially desirable or positive label. Additionally, it would be useful to investigate the role of the importance (to the self) of the trait implied from the label ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1016/j.jpeds.2017.10.028,Psychology_easy_311,But continuing violent disciplinary fear tactics instead of teaching is frankly abuse apologist and triggering to abuse survivors.,"A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59).","You may have turned out ""fine"". But continuing violent disciplinary fear tactics instead of teaching is frankly abuse apologist and triggering to abuse survivors. -- 100% tenidite quevtefani (@scarlettroseV) January 6, 2018

She is ABSOLUTELY right!!","More African Americans endorsed experiencing corporal punishment ""always,"" relative to Hispanic participants, c 2 [1] = 3.96, P < .05, but this difference did not emerge between African American and white participants, c 2 [1] = 1.51, P = .22. A significant positive association emerged for the association between corporal punishment and physical perpetration of dating violence, with an OR of 1.30 (95% CI 1.07-1.59). In the multivariate analysis, controlling for sex, ethnicity, age, parental education, yearly alcohol use, as well as child physical abuse, corporal punishment remained a significant and robust predictor of perpetration of dating violence (aOR 1.29, 95% CI 1.02-1.62; Table III) .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33001285672&p=1pl&v=1&x=mY8JhuBWW01QmuVJVuzYBw
10.1111/cdev.12250,Psychology_easy_313,Here's something you might have figured out at your high school reunion or by Facebook-stalking your old classmates: being one of the cool kids does not necessarily mean being cool for life.,"It remains possible, for example, that teens engaging in pseudomature behavior might possibly maintain a degree of status-based popularity (i.e., perceptions by others that they are members of the ""popular"" group) even if preference-based measures (such as used in this study, indicating other teens' actual desire to spend time with study participants) show declining social preference over time for teens engaging in pseudomature behavior.",Here's something you might have figured out at your high school reunion or by Facebook-stalking your old classmates: being one of the cool kids does not necessarily mean being cool for life. The kids who were deemed cool at a young age were high-status individuals with romantic relationships who broke rules and laws. But they were no longer viewed that way by peers by the time they were in their early 20's.,"The sociometric measure used in this study was a preference-based measure, although in some respects a status-based measure might have more precisely captured the desire of teens to be and appear ""cool"" among peers. It remains possible, for example, that teens engaging in pseudomature behavior might possibly maintain a degree of status-based popularity (i.e., perceptions by others that they are members of the ""popular"" group) even if preference-based measures (such as used in this study, indicating other teens' actual desire to spend time with study participants) show declining social preference over time for teens engaging in pseudomature behavior. Similarly, the measure of valuing popularity, relying solely upon lay usage of the term, did not clearly distinguish between social preference versus social status in peer relationships.",[1],Psychology,train,1.0,news,http://www.scientificamerican.com/podcast/episode/cool-kids-age-poorly/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29
10.1038/s41598-017-03627-7,Psychology_easy_315,"""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said.","To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues.","When he was allowed to hold her hand, their rates fell into sync again and her pain decreased. ""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said. ""Touch brings it back.""","Finally, reporting pain for both emotional and intensity components may shed more light on our findings. To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues. Although this simplified approach allows analyses of human responses, it lacks the sensitivity to capture elements involved in real-life social interactions.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1007/s13524-014-0321-x,Psychology_easy_316,"The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births.","In addition to the type of social learning about the optimal timing and number of children to have , fertility decisions may be affected by observing the subjective experiences of others.","The pattern for second births is similar, although the increase in happiness before and around the birth is roughly half of that for first births. The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.","Not only one's own experience of the transition to parenthood, but also perceiving the well-being of others before and after having children, may affect the tempo and quantum of fertility. In addition to the type of social learning about the optimal timing and number of children to have , fertility decisions may be affected by observing the subjective experiences of others. We find divergent parental well-being trajectories by age at first birth and socioeconomic status.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.jarmac.2014.03.005,Psychology_easy_317,"In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events.","At the lowest -but perhaps also most realistic in practical terms -level of specificity (possibility), warnings mention only the possible presence of misleading or erroneous details in the post-event account.","""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events. It's a problem that psychological scientists may be uniquely qualified to work on.""","(1) Specificity: Warnings vary according to the degree to which they specify the incidence, source and nature of post-event misinformation. At the lowest -but perhaps also most realistic in practical terms -level of specificity (possibility), warnings mention only the possible presence of misleading or erroneous details in the post-event account. This level also includes procedures that can be said to imply the possible presence of misinformation even if this has not been explicitly stated, such as the social post-warnings used by Echterhoff, Hirst, and Hussy (2005; see below in more detail).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1177/0963662516629749,Psychology_easy_318,"Maybe it is churlish to complain that Our Planet, like other such films, avoids showing the uncomfortable truth about just how threatened so much of nature really is.","Using a community-based approach to science problems, working with communities to answer their scientific questions, or using citizen science solutions are all ways to involve members of the public in the scientific process, which can increase their understanding and engagement with science.","As with previous documentaries, you could come away from Our Planet thinking the places being portrayed are completely separate from people. Maybe it is churlish to complain that Our Planet, like other such films, avoids showing the uncomfortable truth about just how threatened so much of nature really is. Perhaps the pure and unsullied vision is what makes them so popular.","Projects can also use the skills of nonscientists in greater capacities, such as determining exposure to pesticides, restoring a natural area, or solving a health problem , . Using a community-based approach to science problems, working with communities to answer their scientific questions, or using citizen science solutions are all ways to involve members of the public in the scientific process, which can increase their understanding and engagement with science. CBR is not an appropriate approach for all topics but should be considered when possible.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.1038/s41598-017-18902-w,Psychology_easy_320,"The assessments are also difficult to administer to very young children, or to people with impairments such as lack of verbal skills, potentially preventing early interventions for these groups.",Our results have thus unraveled a significant correlation between movement and other aspects of Autism development.,"""The use of movement as a 'biomarker' for autism could represent an important leap forward in detection and treatment of the disorder."" The assessments are also difficult to administer to very young children, or to people with impairments such as lack of verbal skills, potentially preventing early interventions for these groups. ""We really need to narrow the gap between what physicians observe in patients in the clinic and what we're learning about movement within the field of neuroscience.""","This result provides added evidence about the independent reliability of using the R-parameter classification. Our results have thus unraveled a significant correlation between movement and other aspects of Autism development. the noise level present in the motor output, may provide an underlying mechanism contributing to the variable motion disturbances present in the spectrum, as well as in other autistic symptons.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1093/chemse/bjt066,Psychology_easy_321,"In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label.",We consider several options to explain this effect.,"""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin - which was rated positively when presented with the label ""Indian food"" - did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","Its positive label yielded faster reaction times than the negative label, which is contrary to our expectations. We consider several options to explain this effect. But since the parmesan cheese odor was categorized as being unpleasant regardless of the label, our prediction can no longer explain this finding.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/smelling-with-our-eyes-descriptions-affect-odour-perception
10.1038/s41598-017-03627-7,Psychology_easy_322,"In the third condition, because of the partner's touch, the women experienced less pain.","Thus, in the following analysis we treated trait empathy as a single factor.","That's almost as many as the entire population of Texas. In the third condition, because of the partner's touch, the women experienced less pain. It seems that hyperscanning, or this brain-to-brain coupling by the act of hand-holding while in pain, may have a soothing, analgesic effect, like the skin-to-skin touch that is beneficial to premature babies.","The analysis revealed a good fit between the measurement model and the data (χ2/df = 1.69, CFI = 0.94, RMSEA = 0.071). Thus, in the following analysis we treated trait empathy as a single factor. Empathic accuracy and trait empathy measurements demonstrated high correlation (r = 0.62, p < 0.001).",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1038/s41598-017-18902-w,Psychology_easy_325,"Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","It is important to emphasize that we are not considering a comparative group statistical analysis, as it is traditionally done in group studies.","The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says. The new motion data strengthens evidence for movement as a biomarker for autism.","The justification for using this smoothing algorithm and the selection of the the smoothing parameter values is provided in the Results and in the Supplementary Material. It is important to emphasize that we are not considering a comparative group statistical analysis, as it is traditionally done in group studies. We found over 90% accuracy when compared to their clinical diagnoses.",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1007/s13524-014-0321-x,Psychology_easy_326,People see that parenthood is easier for older people and choose to have children later.,"The total number of observed births is 7,602 in Germany: 4,513 first births; 2,268 second births; and 536 third births.","""Those who become parents at young ages have a downward happiness trajectory, but those who become parents at older ages and men with more resources have more positive short- and long-term responses to a birth,"" the scientists claim. This fact can also in part explain why mean age of parents has increased. People see that parenthood is easier for older people and choose to have children later.","On average, respondents had 1.7 children during the data collection period. The total number of observed births is 7,602 in Germany: 4,513 first births; 2,268 second births; and 536 third births. The British data hold 4,520 births: 2,689 first births, 1,377 second births, and 295 third births.",[1],Psychology,train,1.0,news,http://www.technology.org/2014/08/27/third-child-make-parents-happier/
10.1016/j.jpeds.2017.10.028,Psychology_easy_327,This abdication of the moral high ground is principled.,"The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment.","Temple is less direct: ""The point of us doing this research isn't to tell parents what to do,"" he said, conjuring a libertarian-friendly approach to science. This abdication of the moral high ground is principled. He is fundamentally opposed to telling people what not to do.","Even after controlling for sex, ethnicity, age, parental education, and child physical abuse, childhood corporal punishment was associated significantly with physical dating violence perpetration (aOR 1.29, 95% CI 1.02-1.62). The finding that childhood corporal punishment was associated with perpetration of young adult physical dating violence, even after controlling for several demographic variables and childhood physical abuse, adds to the growing literature demonstrating deleterious outcomes associated with corporal punishment. (J Pediatr 2018;194:233-7).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1038/s41598-017-18902-w,Psychology_easy_328,The volunteers who scored lower on the scale also exhibited more severe forms of autism.,"Figure 5A , shows that the Rparameter has the power to separate ASD from mature TD.","In each case, the movement-based diagnoses corresponded to these qualitative-based assessments, which are rarely in complete agreement. The volunteers who scored lower on the scale also exhibited more severe forms of autism. Also, lower-than-average scores in several of the volunteers' parents, who did not have an autism diagnosis themselves, suggested that movement could possibly be used to assess a neurotypical parent's risk for children with autism, Jose says.","The R-parameter provides a quantatitive classification of ASD. Figure 5A , shows that the Rparameter has the power to separate ASD from mature TD. They suggested a possible motor connection of ASD abnormalities with core autism characteristics 35 .",[1],Psychology,train,1.0,news,http://www.futurity.org/autism-movement-test-1656982-2/
10.1016/j.jarmac.2014.03.005,Psychology_easy_329,"Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign.",few comments are in order.,"Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs. Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign. ""[T]hey are likely to 'remember' scandals that reflect poorly on the opposing candidate,"" Murphy told the Association for Psychological Science.","[86] few comments are in order. Principally, post-warnings can be effective through undermining any of the processes that otherwise (i.e., in the absence of a post-warning) are supposed to lead to a misinformation effect.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1186/2045-5380-3-19,Psychology_easy_330,"That said, due to the withdrawal symptoms of Adderall, those with ADHD should consult their doctor before changing their treatment.",The most consistent data indicate that acute and repeated restraint stress decreases AEA levels in multiple limbic brain regions but robustly in the amygdala .,"As such, CBD can also be seen as the best alternative to Adderall for adults with ADHD. That said, due to the withdrawal symptoms of Adderall, those with ADHD should consult their doctor before changing their treatment. But, the stabilizing effects of CBD can help patients through withdrawal.","In addition, CB1 receptor antagonism exaggerates acute restraint stress-induced deficits in sucrose preference , with the magnitude of this effect intensifying with increasing duration of restraint stress exposure. The most consistent data indicate that acute and repeated restraint stress decreases AEA levels in multiple limbic brain regions but robustly in the amygdala . In some cases more repeated bouts of stress produced larger decreases in AEA levels , and the reduction lasts at least 24 hours after termination of the last stressor .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1038/s41598-017-03627-7,Psychology_easy_331,My hand got sweaty.,"Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling.","Almost immediately, I was acutely aware of all the two-handed things I could no longer do: fix my ponytail, uncap the water bottle in my purse. My hand got sweaty. I'd spent so long with a man who resisted any attempts at hand-holding that it had never really occurred to me that I might not like it, either.","Our findings confirm that interpersonal touch as compared to no-touch is associated with increased respiration coupling, during both pain and no-pain conditions. Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling. The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1093/jcr/ucw012,Psychology_easy_333,"When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color.","After responding to the instructional manipulation check, all participants then reported their liking for the advertisement (1 ¼ Not at all, 7 ¼ Very much; M behavioral ¼ 4.74 vs. M identity salience ¼ 4.44 vs. M nontargeted ¼ 4.15; F(2, 144) ¼ 1.97, p ¼ .14) and indicated how likely they would be to purchase a Movado watch (1 ¼ Not at all likely, 7 ¼ Very likely).","Some of this research hints at the memory-distorting power of brief visual distractions. When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color. Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice.","[yes/no]), resulting in a sample of 147 (59% females; M age ¼ 20.6) for all analyses. After responding to the instructional manipulation check, all participants then reported their liking for the advertisement (1 ¼ Not at all, 7 ¼ Very much; M behavioral ¼ 4.74 vs. M identity salience ¼ 4.44 vs. M nontargeted ¼ 4.15; F(2, 144) ¼ 1.97, p ¼ .14) and indicated how likely they would be to purchase a Movado watch (1 ¼ Not at all likely, 7 ¼ Very likely). (1 ¼ Not at all, 7 ¼ Very much Implied Social Labels and Self-Perceptions Mediate Purchase Likelihood for Advertised Product.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1111/cdev.12250,Psychology_easy_334,"For these teens, being popular was their highest goal, Allen said.","This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time.","What researchers found was that the kids considered cool in the 8th grade had already peaked by the time they reached high school. For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol.","One potential explanation for these findings is provided by cumulative continuity theory . This theory suggests that efforts to attain status with peers via superficial, pseudomature behaviors might lead to future difficulties because these pseudomature behaviors replace efforts to develop positive social skills and meaningful friendships and thus leave teens less developmentally mature and socially competent over time. Early pseudomature behavior also predicted higher adult levels of more serious criminal behavior, alcohol and drug use, and problems associated with such use.",[1],Psychology,train,1.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1093/jcr/ucw012,Psychology_easy_335,"When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color.","In the condition in which the hot chocolate was positioned as appropriate for the outdoors, we expected significant mediation only at moderate and high levels of a priori interest in outdoors products (i.e., when targeting was at least moderately accurate).","Some of this research hints at the memory-distorting power of brief visual distractions. When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color. Even though their guesses were often way off, many of the distracted folks indicated that they had high confidence in their choice.","In support of our expectation, the analyses revealed that the outdoorsy labeling index mediated the effect of targeting on purchase intentions for the solar charger (b ¼ .04, SE ¼ .02, 95% CI, .0064-.1146]) but not the hot chocolate (b ¼ À.01, SE ¼ .02, 95% CI, À.0578 to .0309). In the condition in which the hot chocolate was positioned as appropriate for the outdoors, we expected significant mediation only at moderate and high levels of a priori interest in outdoors products (i.e., when targeting was at least moderately accurate). In contrast, in the condition in which the hot chocolate was positioned as appropriate for the indoors, purchase intentions should be noncontingent on self-perceptions at any level of a priori interest in outdoorsy products because perceiving oneself as more or less outdoorsy should not have much influence on interest in purchasing hot chocolate for indoor useeven outdoorsy people may drink hot chocolate indoors.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1001/jamapsychiatry.2018.1941,Psychology_easy_336,"While this particular study found strong neural connections in the association of depressive problems with poor sleep quality, rather than the other way around, in general the effects can work both ways.","In other words, the increases of the 39 functional connectivities shown in Fig.","From the other side, people with insomnia also have a higher risk of depression and anxiety. While this particular study found strong neural connections in the association of depressive problems with poor sleep quality, rather than the other way around, in general the effects can work both ways. Getting to the bottom of exactly what's going on will require more research, but one of the more promising avenues to explore is the role of the lateral orbitofrontal cortex.","S4 ) than for the effect in the opposite direction described above. In other words, the increases of the 39 functional connectivities shown in Fig. 1D mediated the effect of depressive problems on sleep quality, and the effect was weaker in the opposite direction.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1038/s41598-018-30980-y,Psychology_easy_338,"Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children.""","If such were the case, REM in subsequent overnight sleep may support delayed emotional memory processing.","Together, ""these results suggest that sleep bouts can interact to benefit memory in early childhood,"" they conclude. Overall, the authors report, ""results of this study are consistent with those in procedural memory consolidation in preschool-aged children."" As in observations by others, ""both a nap and subsequent overnight sleep was necessary to observe performance benefits.""","Thus, naps may not be sufficient for emotional memory consolidation. If such were the case, REM in subsequent overnight sleep may support delayed emotional memory processing. For example, selective memory for negative aspects of complex scenes is positively correlated with both SWS and SWA during a nap, although correlated with nocturnal REM sleep .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34884544095&p=1pl&v=1&x=ZTfu4WJpcprjoFwmcebiPw
10.1016/j.jalz.2018.06.2856,Psychology_easy_339,"Eye checkups could be used to screen people with a greater risk of Alzheimer's perhaps - and while there's no cure yet, appropriate care could be provided earlier.",Limitations of our study include a geographically confined cohort.,"""The main message from this study is that ophthalmologists should be more aware of the risks of developing dementia for people with these eye conditions, and primary care doctors seeing patients with these eye conditions might be more careful on checking on possible dementia or memory loss."" Eye checkups could be used to screen people with a greater risk of Alzheimer's perhaps - and while there's no cure yet, appropriate care could be provided earlier. Age-related macular degeneration, diabetic retinopathy, and glaucoma were the three eye conditions that showed a strong link with Alzheimer's.","Cataract is as strongly agerelated as the other conditions we studied, and we found no association between cataract and AD risk. Limitations of our study include a geographically confined cohort. The study population's ethnic and socioeconomic characteristics are similar to the surrounding county, but whether these associations would hold in nonwhite ethnic groups is unknown.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34771794923&p=1pl&v=1&x=Ca84A-gkCictgVqjQU3CrA
10.1016/j.jarmac.2014.03.005,Psychology_easy_340,This meant that voters were relatively well informed about both sides.,"misinformation, whereas the two other dimensions go beyond this purely instructional level by also affecting people's motivation to rely on the post-event account versus their own memory of the event.","""[T]hey are likely to 'remember' scandals that reflect poorly on the opposing candidate."" This meant that voters were relatively well informed about both sides. Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs.","The first dimension affects participants' knowledge about the prevalence and nature of [79] [80] misinformation, whereas the two other dimensions go beyond this purely instructional level by also affecting people's motivation to rely on the post-event account versus their own memory of the event. A particular difficulty resulted from the fact that some studies explicitly compared a post-warning condition to a standard, no-warning condition, whereas others just used a post-warning as part of their general procedure, without focusing on the warning in its own right.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1002/eat.20625,Psychology_easy_341,"Dieting is no longer a necessary problem of vanity, as it has been historically termed, but a problem of knowledge and efficiency--a rhetorical shift with broad implications for how people think of themselves.",Our findings suggest that inappropriate compensatory behaviors occur at disconcertingly high levels among women and men.,"Dieting is no longer a necessary problem of vanity, as it has been historically termed, but a problem of knowledge and efficiency--a rhetorical shift with broad implications for how people think of themselves. The firm found that that was due to two things: the growing popularity of the size-acceptance movement, and dieter fatigue. For new companies, laundering what are often fairly conventional diet practices through the language of technology provides the imprimatur of newness in the eyes of seasoned dieters, as well as a Trojan horse to reach consumers who, for whatever reason, were never interested in dieting qua dieting.","We note, however, these differences, although statistically significant, are weak: for every 50 women studied one more case that meets the particular binge eating criterion would be expected than for every 50 men studied. Our findings suggest that inappropriate compensatory behaviors occur at disconcertingly high levels among women and men. For example, almost 4% of women reported vomiting ""often"" during the past three months in order to compensate for overeating.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37544034795&p=1pl&v=1&x=nSrZYazEZSBbGoNGR6w7Vg
10.1016/j.jarmac.2014.03.005,Psychology_easy_344,"Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign.",The corresponding reduction in terms of Original Memory (cf.,"Even so, Murphy and her colleagues found that voters, after seeing fake news stories, tended to form false memories about stories that particularly aligned with their political beliefs. Participants voting yes to repeal the ban on abortion, for instance, were more likely to recall the fabricated poster scandal about the opposing campaign. ""[T]hey are likely to 'remember' scandals that reflect poorly on the opposing candidate,"" Murphy told the Association for Psychological Science.","As an aside, we can derive from these figures (and the corresponding ones for Original Memory), another way of expressing the reduction of the misinformation effect after post-warning, which is perhaps more intuitive than the measure derived from the odds ratios earlier (in the main results I section): The initial performance difference of 42.3% -17.7% = 24.6% was reduced to 28.5% -19.5% = 9.1% (rounding error) after post-warning. The corresponding reduction in terms of Original Memory (cf. Table 2 ) was from an initial 23.2% difference to an 8.1% difference after post-warning.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1038/s41598-017-03627-7,Psychology_easy_345,"""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands.""","To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues.","The whole thing seems so nice -- to be able to think of this gesture first and foremost as emotionally empowering, rather than physically limiting. ""Perhaps,"" Avins wrote of the Trumps-holding-hands incident, ""it's time to acknowledge a new norm: Some of us just really don't want to hold hands."" This is very true.","Finally, reporting pain for both emotional and intensity components may shed more light on our findings. To conclude, we show here that touch regulates physiological coupling during pain, suggesting that interpersonal coupling is affected by various contextual social cues. Although this simplified approach allows analyses of human responses, it lacks the sensitivity to capture elements involved in real-life social interactions.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1038/s41598-017-03627-7,Psychology_easy_346,My hand got sweaty.,"Thus, future research should test the role of oxytocin in touch-related analgesia.","Almost immediately, I was acutely aware of all the two-handed things I could no longer do: fix my ponytail, uncap the water bottle in my purse. My hand got sweaty. I'd spent so long with a man who resisted any attempts at hand-holding that it had never really occurred to me that I might not like it, either.","It was demonstrated that warm touch can increase the levels of plasma oxytocin, and reduce stress 78 and depression 79 . Thus, future research should test the role of oxytocin in touch-related analgesia. It is important to note that our findings of interpersonal coupling during touch can also be explained by the phenomenon of Huygens synchronization of two connected pendulum clocks 83 .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1016/j.jalz.2018.06.2856,Psychology_easy_347,"Another degenerative eye condition, a cataract, wasn't an Alzheimer's disease risk factor, the researchers found.","Restricting the ""recent"" diagnosis window to 2 years resulted in a higher HR for recent glaucoma ( Table 3 ).","Another degenerative eye condition, a cataract, wasn't an Alzheimer's disease risk factor, the researchers found. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye."" The eye even has the same type of tissues as the brain, the researchers said.","Risk estimates assessing each disease on its own model were similar to those in primary models (Supplementary Table 2 ). Restricting the ""recent"" diagnosis window to 2 years resulted in a higher HR for recent glaucoma ( Table 3 ). Use of alpha agonists did not confound associations between glaucoma and AD (Supplementary Table 4 ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34761732564&p=1pl&v=1&x=Vhq6mvjHkQ2mz_7WovQGRw
10.1186/2045-5380-3-19,Psychology_easy_348,"This, in turn, helps improve focus and attention in those with ADHD.","Interestingly, as in the parabolic flight study, this study also reported that lower basal levels of AEA predicted increased HPA responses to stress, again suggesting that eCB signaling negatively relates to the magnitude of the stress response .","It works by heightening CNS connections to control hyperactivity and impulses. This, in turn, helps improve focus and attention in those with ADHD. The overall effect is to bring the brain down from a state of over-stimulation to a normal, baseline stimulation level.","Hill and colleagues demonstrated that exposure to the Trier social stress test resulted in a significant increase in 2-AG concentrations (and a small trend toward increased AEA concentrations) in the circulation. Interestingly, as in the parabolic flight study, this study also reported that lower basal levels of AEA predicted increased HPA responses to stress, again suggesting that eCB signaling negatively relates to the magnitude of the stress response . As such, these studies demonstrate that eCB signaling in humans is responsive to stress, and that failure of this system to be appropriately engaged results in increased responses to stress.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38859700967&p=1pl&v=1&x=UP_btp_fYMUlHDGz6aK1Xw
10.1038/s41598-017-03627-7,Psychology_easy_350,""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being.","Similar to respiration fluctuations, trait empathy showed a pattern of moderation similar to that of empathic accuracy.",""" "" Holding hands can actually ease pain, helping to regulate responses to stress, while increasing trust and emotional well-being. They probably had no idea that their poppy little ditty had a basis in scientific fact. That's almost as many as the entire population of Texas.","However, these contrasts were not significant in the no-touch conditions (Δζ nt(p) = 0.003, p = 0.67, males), (Δζ nt(p) = 0.022, p = 0.17, females). Similar to respiration fluctuations, trait empathy showed a pattern of moderation similar to that of empathic accuracy. However, the moderation effect of trait empathy did not contribute beyond empathic accuracy and women's analgesia.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1016/j.jpeds.2017.10.028,Psychology_easy_351,"But the focus is positive, not punitive, on how to build healthy relationships.","Of these participants, 61% were female, with a mean age of 20.03 (SD = 0.76).","At a larger scale, Temple believes one promising approach is school-based teaching of relationship skills. But the focus is positive, not punitive, on how to build healthy relationships. Temple believes this work is relevant to the national conversation on sexual assault and harassment.","One factor that merits additional attention is the association between a youth's history of experiencing corporal punishment and perpetration of dating violence. Of these participants, 61% were female, with a mean age of 20.03 (SD = 0.76). Participants were Hispanic (32.6%), white (28.8%), African American (26.0%), and other (12.7%).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32755946603&p=1pl&v=1&x=0KWopEIxShdttKNVIWuAxg
10.1016/j.nicl.2013.09.001,Psychology_easy_352,"""If a diagnosis is already attached to an image from the data bank, that could steer the physician in the right direction.","Like volumetric measures, statistical shape analysis based on the diffeomorphometry allows us to transfer morphometry changes across coordinate systems to template coordinates across which statistics can be obtained in the dataset.","The new pediatric brain imaging data bank, Miller said, will be useful in at least two ways. ""If a diagnosis is already attached to an image from the data bank, that could steer the physician in the right direction. Also, the scans in our library may help a physician identify a change in the shape of a brain structure that occurs very early in the course of a disease, even before clinical symptoms appear.","Longitudinal MRI data in cognitively normal individuals who have progressed to mild impairment is extremely limited, but also suggests that volumetric measures of medial temporal lobe regions may be useful in predicting progression from normal cognition to mild or moderate impairment. Like volumetric measures, statistical shape analysis based on the diffeomorphometry allows us to transfer morphometry changes across coordinate systems to template coordinates across which statistics can be obtained in the dataset. This allows for the detection of changes in brain structures which are not uniformly distributed, and may be locally occurring.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/children-s-brain-image-bank-could-become-a-google-tool-for-doctors
10.1093/chemse/bjt066,Psychology_easy_354,"Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels.",There were no outliers for the intensity and pleasantness measures.,"The result was that all participants rated the four odours more positively when they were presented with positive labels than when presented with negative labels. Specifically, participants described the odours as pleasant and edible (even those associated with non-food items) when associated with positive labels. Conversely, the same odours were considered unpleasant and inedible when associated with negative labels - even the food odours.",We also removed 7 outliers from 460 data points for the edibility measures. There were no outliers for the intensity and pleasantness measures. Missing data points led to a listwise exclusion of the participant's data.,[1],Psychology,train,1.0,news,http://www.healthcanal.com/eyes-vision/47601-smelling-with-our-eyes-descriptions-affect-odour-perception.html
10.1111/cdev.12370,Psychology_easy_355,"Regulating emotions

Young people who reflected on their experiences from a self-distanced perspective became less upset than those who reflected from a self-immersed perspective, according to the study in Child Development.","Rather, it led participants to approach the event with greater objectivity.","Regulating emotions

Young people who reflected on their experiences from a self-distanced perspective became less upset than those who reflected from a self-immersed perspective, according to the study in Child Development. In part, this was because adolescents who saw their experience from a distance thought about it differently. These teens were more likely to reconsider the events in meaningful and insightful ways and less likely to simply replay the upsetting events in their minds.","Importantly, despite some research in the clinical domain that equates distancing with emotional detachment (e.g., , self-distancing did not lead to avoidance in any of these studies. Rather, it led participants to approach the event with greater objectivity. If self-distancing follows a similar developmental trajectory to other regulatory strategies, such as distraction or reappraisal, its use should increase from childhood through adolescence .",[1],Psychology,train,1.0,news,http://www.futurity.org/teens-emotions-distance-903192/
10.3402/ejpt.v5.22250,Psychology_easy_356,aAbove all your therapist should be someone who respects you and your whole system.,It distinguishes between interpersonal trauma inflicted by someone with whom the victim was close to (betrayal trauma) and the same trauma committed by not-close perpetrators.,"This Is My Brave, Inc. on YouTube

If you are diagnosed with DID and seeking treatment, working with trauma-informed providers is essential, Joubert says. aAbove all your therapist should be someone who respects you and your whole system. Therapists who refuse to acknowledge alters or say their names, [and who] push you to remember trauma or integrate when you aren't ready, may do more damage than good.",TestÁretest reliability has been reported to range from 0.79 to 0.96 and split-half reliability as 0.83 () . It distinguishes between interpersonal trauma inflicted by someone with whom the victim was close to (betrayal trauma) and the same trauma committed by not-close perpetrators. The BBTS has good testÁretest reliability ).,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38920678242&p=1pl&v=1&x=_UY1KqSAMnWKI6YGx_CLrw
10.1073/pnas.1505114112,Psychology_easy_357,These findings suggest that musical training could keep that window open longer.,"Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function.","At the end of 3 years, those students who had played instruments were better at detecting speech sounds, like syllables and words that rhyme, than their JROTC peers, the team reports online today in the Proceedings of the National Academy of Sciences. These findings suggest that musical training could keep that window open longer. But the benefits of music aren't just for musicians; taking up piano could be the difference between an A and a B in Spanish class.","Our results support the notion that the adolescent brain remains receptive to training, underscoring the importance of enrichment during teenage years. Both types of training required investment of time and effort and emphasized the development of self-discipline, dedication, and determination; however, only the music training targeted auditory function. The JROTC group exhibited the waning of response consistency characteristically observed between adolescence and young adulthood .",[1],Psychology,train,1.0,news,http://news.sciencemag.org/brain-behavior/2015/07/benefits-band-class
10.1111/cdev.12250,Psychology_easy_358,"The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Na€ ıve coding systems are designed to capture typical lay notions of constructs, and attain reliability by compositing ratings from multiple raters, and in this case yielded highly reliable ratings at ages 13 (ICC = .93), 14 (ICC = .89), and 15 (ICC = .87).","For these teens, being popular was their highest goal, Allen said. According the study, by the time they reached the age of 22, the once-popular teens were perceived as less competent, and were more likely to have problems with drugs and alcohol. The teens' ""pseudomature behavior,"" as the researchers call it, ""predicted long-term difficulties in close relationships, as well as significant problems with alcohol and substance use, and elevated levels of criminal behavior,"" the study said.","Dynamic physical attractiveness (i.e., capturing static appearance as well as movement and expressive behavior) was reliably coded using a na€ ıve rater strategy . Na€ ıve coding systems are designed to capture typical lay notions of constructs, and attain reliability by compositing ratings from multiple raters, and in this case yielded highly reliable ratings at ages 13 (ICC = .93), 14 (ICC = .89), and 15 (ICC = .87). Internal consistency of the combined measure across ages was good, Cronbach's a = .77.",[1],Psychology,train,1.0,news,http://www.cbsnews.com/news/cool-kids-dont-stay-popular-forever/
10.1080/09500693.2018.1540897,Psychology_easy_359,The Report Card also showed that several STEM institutions had started programs like unconscious bias training to help female scientists flourish.,"Therefore, such case studies or mixed method studies with a pre/post-test design were classified as 'weak causal evidence' as well.","""European institutions had significantly higher grades than North American institutions, suggesting that perhaps the well-known progressive policies of European countries aimed at supporting working parents and promoting work-life balance have some influence on the retention and promotion of women in science,"" Dr. Beeler says. The Report Card also showed that several STEM institutions had started programs like unconscious bias training to help female scientists flourish. Fixing gender inequality in STEM is a big ask, but the experts behind the Report Card are hopeful that it can happen, with the right policies and intervention.","However, because these outcomes are perceptions of changes, they cannot provide evidence for actual changes in interest or persistence in STEM due to the programme. Therefore, such case studies or mixed method studies with a pre/post-test design were classified as 'weak causal evidence' as well. The electronic search yielded 918 studies in total.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1093/chemse/bjt066,Psychology_easy_360,"""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.",We tested 50 subjects.,"""We were surprised by this result because we expected reaction times to increase when all four odours were associated with positive labels,"" says Manescu. In this study, however, cumin -- which was rated positively when presented with the label ""Indian food"" -- did not result in a slower reaction time, unlike parmesan cheese, which yield slower reaction times and was rated positively when presented with the ""parmesan cheese"" label. ""Although descriptions appear to influence reaction time, this may be modulated by label fit and the edibility attributed to an odour or label,"" concludes Manescu.","We tested 50 subjects. Because of a lack of fit, only 4 of the initial 5 odorants were analyzed. All odorants presented with positive labels were rated as being more edible than when they were presented with negative labels.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/02/140211084007.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0963662516629749,Psychology_easy_361,"and the mind-boggling behaviours of birds (such as the manakins shown doing a shuffle dance), Our Planet will engage a whole new generation.","These comments outlined the public as being comprised of many different kinds of people, but the nature of the responses suggested that the respondent was distinct from this group.","So many of us working in conservation were drawn in through watching Sir David Attenborough's other films as children. and the mind-boggling behaviours of birds (such as the manakins shown doing a shuffle dance), Our Planet will engage a whole new generation. However feeling connected with nature does matter.","Approximately 22% of the coded responses conceptualized the public as a neutral other. These comments outlined the public as being comprised of many different kinds of people, but the nature of the responses suggested that the respondent was distinct from this group. Responses in this category contained no positive or negative judgments or feelings about the public, with comments often linking the idea of the public to participation in social life and activities, such as voting, consuming media, or interacting with the government.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.1016/j.jalz.2018.06.2856,Psychology_easy_362,"""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine.","However, cataract is a disease of the lens, so it does not share pathophysiological mechanisms with AD.","Cataract diagnosis was not an Alzheimer's disease risk factor. ""What we found was not subtle,"" said Dr. Paul Crane, professor of medicine, Division of General Internal Medicine, at the UW School of Medicine. ""This study solidifies that there are mechanistic things we can learn from the brain by looking at the eye.""","Cataract is similar in being heavily age-related. However, cataract is a disease of the lens, so it does not share pathophysiological mechanisms with AD. Procedures to address cognitive assessment of individuals with poor vision have been in place since the inception of the study; these procedures are detailed in the eSupplement.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34769213463&p=1pl&v=1&x=UVvlj5AQUfbG2OpYDI_gHw
10.1007/s13524-014-0321-x,Psychology_easy_363,"""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.",The happiness trajectories of parents were quite similar in the pooled cross-sectional OLS regressions and the fixed-effects regressions.,"Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future. ""The arrival of a third child is not associated with an increase in the parents' happiness, but this is not to suggest they are any less loved than their older siblings.","Social norms and social policy may play some role in shaping parental wellbeing trajectories, but overall, the individual sociodemographic characteristics are more important than context. The happiness trajectories of parents were quite similar in the pooled cross-sectional OLS regressions and the fixed-effects regressions. This suggests that in the populations analyzed, there is relatively little selection that is not accounted for by our control variables.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/cdev.12250,Psychology_easy_364,The pseudomature behavior that seemed so admirable at a young age lost cache as the other kids gained actual maturity.,Several other potential limitations also apply to these findings.,"But they were no longer viewed that way by peers by the time they were in their early 20's. The pseudomature behavior that seemed so admirable at a young age lost cache as the other kids gained actual maturity. Meanwhile, as the young James Deans and Miley Cyruses aged they had to engage in ever-riskier behavior to keep thinking of themselves as cool.","Rather, it is that engaging in these behaviors very early in adolescence, and as an apparent means of seeking peer status, is a significant marker of future risk. Several other potential limitations also apply to these findings. First, although the longitudinal and lagged analyses conducted in this study are sufficient to reject causal hypotheses, they cannot demonstrate the presence of causal pathways.",[1],Psychology,train,1.0,news,http://www.scientificamerican.com/podcast/episode/cool-kids-age-poorly/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciam%2Fmind-and-brain+%28Topic%3A+Mind+%26+Brain%29
10.1007/s13524-014-0321-x,Psychology_easy_366,(c) iStock Sera que ter filhos e sinonimo de felicidade?,These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing.,"(c) iStock Sera que ter filhos e sinonimo de felicidade? Outro, mais recente, aponta que o ideal esta nos dois e que mais pode contrariar o indice de felicidade dos pais. A maioria dos europeus adultos considera que a familia ideal e composta por dois filhos, nem mais nem menos.","Similarly, given that we find no positive gain in subjective well-being for third births, the documented differences by parity may help explain the low quantum of fertility. These results provide a new way of understanding the theories of fertility decline by showing that the fertility behavior that emerged during the second demographic transition would have been largely predicted by parents' subjective well-being response to childbearing. However, when the question is how children influence parental well-being, it is important to analyze individual changes over time instead of only comparing parents with the childless.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1016/j.jarmac.2014.03.005,Psychology_easy_368,"It's a problem that psychological scientists may be uniquely qualified to work on.""","It seems unlikely of course that the post-warning procedures used in eyewitness settings can be directly translated into corrections of initial misinformation, but there are some interesting resemblances.","""That the political orientation and cognitive-ability effects persisted... despite an explicit warning about possible fake news in the second part of the study suggests that these effects cannot simply be eliminated by encouraging stricter source monitoring,"" the authors conclude. In other political contexts, such as the 2020 U.S. presidential election, fake news may create similar effects in voters' recollections of campaign events. It's a problem that psychological scientists may be uniquely qualified to work on.""","[87] It seems unlikely of course that the post-warning procedures used in eyewitness settings can be directly translated into corrections of initial misinformation, but there are some interesting resemblances. (2012, p. 117) state that ""the continued influence of misinformation can be eliminated through the provision of an alternative account that explains why the information was incorrect"", which reminds of the logic of the enlightenment procedure that also gives reasons for the presence of misinformation.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1080/09500693.2018.1540897,Psychology_easy_370,The pipeline wasn't the only issue revealed in the Report Card.,This observed difference in ability is too small to account for the large difference in STEM participation.,"""Unfortunately, it appears that the pipeline is leaking a with a consistent drop in the proportion of women at each rung of the professional ladder. The pipeline wasn't the only issue revealed in the Report Card. Dr. Beeler tells Bustle that the Report Card also showed women were underrepresented at important committees and external conferences.",also conclude that the validity of the results in research on STEM ability is questionable. This observed difference in ability is too small to account for the large difference in STEM participation. They suggested that the underrepresentation of females in STEM education can be (partly) explained by the higher level of verbal ability of girls compared with that of boys.,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40221871852&p=1pl&v=1&x=YoxlwItGkxllKvqs__4klg
10.1038/s41598-017-03627-7,Psychology_easy_371,"Holding hands is the one form of PDA that you can almost always pull off without being obnoxious, and the only one that retains its sweetness across the entire human lifespan.","Interestingly, the difference in pain between the conditions with and without touch was higher in females than in males, who estimated their partners' pain.","And it's lonely being on the outside, especially when the experience in question is such a quietly lovely one. Holding hands is the one form of PDA that you can almost always pull off without being obnoxious, and the only one that retains its sweetness across the entire human lifespan. It's akin to the first time you sleep over at someone's place without actually sleeping with them -- an act steeped in intimacy because of, not in spite of, the fact that it's sexless.","Nevertheless, the moderation effects of empathic accuracy and pain analgesia reduce the probability of this explanation. Interestingly, the difference in pain between the conditions with and without touch was higher in females than in males, who estimated their partners' pain. These findings can be explained by the fact that female participants experienced the real pain and their male partners only guessed the females' pain level.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33905342690&p=1pl&v=1&x=oCe4HgFpEBY4nR9WXUdauQ
10.1007/s13524-014-0321-x,Psychology_easy_372,(c) iStock Sera que ter filhos e sinonimo de felicidade?,"A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain.","(c) iStock Sera que ter filhos e sinonimo de felicidade? Outro, mais recente, aponta que o ideal esta nos dois e que mais pode contrariar o indice de felicidade dos pais. A maioria dos europeus adultos considera que a familia ideal e composta por dois filhos, nem mais nem menos.","Mature parents (ages 35-49) have increasing happiness before and during the birth year; then, after a small drop, happiness remains at or above baseline. A test for whether the coefficients for 3-4, 5-9, and 10-18 years after birth are all 0 suggests increased long-run happiness (p < .05) in Germany and a borderline significant result (p < .10) in Britain. Among both the partnered and unpartnered, happiness increases around the birth and then decreases 11 Parents aged 17 or younger are excluded because (1) teenage childbearing is a different process than having children at young adult ages; (2) our samples include very few people who had children before turning age 18; and (3) it is difficult to construct a meaningful pre-birth baseline happiness for teen parents.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39223136203&p=1pl&v=1&x=xoHDe39xmXgtQulrl1DHEQ
10.1016/j.jalz.2018.06.2856,Psychology_easy_373,The researchers said several factors suggest the effects they uncovered were specific to ophthalmic conditions and not merely age-related phenomenon.,"Recent and established AMD and DR were associated with allcause dementia, and risks for DR were much larger (Supplementary Table 1 ).","She said a better understanding of neurodegeneration in the eye and the brain could bring more success in diagnosing Alzheimer's early and developing better treatments. The researchers said several factors suggest the effects they uncovered were specific to ophthalmic conditions and not merely age-related phenomenon. ""This paper is pointing to a new area of opportunity,"" he said.","Restricting to probable AD (n 5 522) resulted in similar estimates for recent ( For all-cause dementia, glaucoma risks were attenuated though still non-null for recent diagnosis. Recent and established AMD and DR were associated with allcause dementia, and risks for DR were much larger (Supplementary Table 1 ). Models with non-AD dementia that treated AD as a competing risk confirmed the expected strong relationship between DR and non-AD dementia (Supplementary Table 1 ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34765487148&p=1pl&v=1&x=ufEabPDBICA34OF2ZCudfA
10.1038/s41598-017-03627-7,Psychology_easy_374,"Read Time:

Fathers-to-be, take note: You may be more useful in the labor and delivery room than you realize.","The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 .","Read Time:

Fathers-to-be, take note: You may be more useful in the labor and delivery room than you realize. When leaders and followers or therapists and clients have a good rapport, their brainwaves fall into a similar pattern. The authors hope it can inform the discussion as health care providers seek opioid-free pain relief options.","Moreover, tactile-induced analgesia 66 correlates with activations in brain areas related to multimodal neural activity 67 and emotional processes . The partner's touch may also enhance inter-partner brain synchronization in areas related to the pain matrix, a hypothesis that should be tested in future research using novel hyperscanning techniques 73 . The ACC appears to play a role in a variety of autonomic functions, such as regulating heart rate and blood pressure 76 .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1016/j.jpeds.2017.10.028,Psychology_easy_375,"""We justify spanking, but there is no other relationship in the world that it would be okay to hit someone, even if they did something wrong.""","Hence, the modeling may occur in childhood due to direct experience of parental violence, witnessing interparental violence, or both.","For example, although the fear of being hit can temporarily prevent a child from doing a problematic behavior, in the long run it may have psychological consequences. ""We justify spanking, but there is no other relationship in the world that it would be okay to hit someone, even if they did something wrong."" Werner-Wilson emphasized that research shows not all corporal punishment is negative, and if it is done under certain parameters, such as being conducted soon after the punishable act and being done without a strong emotional reaction from the parent, the results can be positive.","Due to item missingness, the sample sizes for sex, ethnicity, and highest parental education may not match. Hence, the modeling may occur in childhood due to direct experience of parental violence, witnessing interparental violence, or both. Our study has certain limitations.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=32698329640&p=1pl&v=1&x=pR-rCOq5zncqbaREgJOeFg
10.1176/appi.ajp.2018.17111282,Psychology_easy_376,The tests they researched also didn't agree on what medical recommendations to make when they detected that a patient had a particular gene variant.,"This step, in part, reflects an attempt to understand the patient's unique genetic background and biological ""substrate.""","The team analyzed four tests (CNSDose, Genecept, GeneSight, and Neuropharmagen) and found that they could reliably detect whether someone has a certain genetic variant, says Dunlop. The tests they researched also didn't agree on what medical recommendations to make when they detected that a patient had a particular gene variant. Even though 23andMe has been more successful than other companies in gaining FDA approval, that doesn't mean its test is useful or necessary.","They find that, at present, there are insufficient data to support the widespread use of combinatorial pharmacogenetic testing in clinical practice, although there are clinical situations in which the technology may be informative, particularly in predicting side effects. This step, in part, reflects an attempt to understand the patient's unique genetic background and biological ""substrate."" In the majority of cases, the clinician will be faced with a decision regarding alternative strategies to treat the patient's depression.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37574117193&p=1pl&v=1&x=ptbwG_dACdLouZko2EPU2w
10.1016/j.jarmac.2014.03.005,Psychology_easy_378,"""High cognitive ability may allow individuals to overcome the biasing effect of political orientation and more effectively monitor the sources of their memories,"" the authors note.","Similarly, post-warnings immediately after presentation of misinformation could still affect its encoding and certainly its rehearsal.","But participants who scored high on the cognitive ability test were more adept at identifying whether a story that aligned with their beliefs was fake. ""High cognitive ability may allow individuals to overcome the biasing effect of political orientation and more effectively monitor the sources of their memories,"" the authors note. The current study, however, finds that even when fabricated events are presented with a warning about their legitimacy, false memories are easily created.","better scrutiny of the post-event information), enhanced remembering, or both. Similarly, post-warnings immediately after presentation of misinformation could still affect its encoding and certainly its rehearsal. By contrast, effects of post-warnings immediately before testing can only be due to an influence at the remembering (i.e., retrieval or reporting) stage.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40067995115&p=1pl&v=1&x=GnYhPhnViURXym3lXBtkaw
10.1038/s41598-017-03627-7,Psychology_easy_379,"When he was allowed to hold her hand, their rates fell into sync again and her pain decreased.",The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain.,"But when she was subjected to pain and he couldn't touch her, that synchronization was severed. When he was allowed to hold her hand, their rates fell into sync again and her pain decreased. ""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said.","Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling. The finding of an increased pattern of heart rate coupling during the pain and touch condition indicates that touch may allow communication between the participants but only during pain. This indicates that coupling .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1038/s41598-017-03627-7,Psychology_easy_380,"According to Goldstein, ""it's unlikely that this research will solve the problem of painkillers.""","Our findings confirm that interpersonal touch as compared to no-touch is associated with increased respiration coupling, during both pain and no-pain conditions.","There's more research to be done, for instance, focusing on clinical implications of these findings and even implications of empathy training. According to Goldstein, ""it's unlikely that this research will solve the problem of painkillers."" For now, it's worth a try.","In addition, the females' feeling of comfort during the touch did not moderate coupling in respiration fluctuations (F (4,28000) = 1.37, p = 0.24) nor heart rate (F (4,13000) = 1.47, p = 0.21). Our findings confirm that interpersonal touch as compared to no-touch is associated with increased respiration coupling, during both pain and no-pain conditions. Thus, in the current study the partners may have communicated their emotions via touch, as evidenced by an increase in physiological coupling.",[1],Psychology,train,1.0,news,https://health.howstuffworks.com/human-body/systems/nervous-system/holding-hands-can-ease-pain.htm#mkcpgn=rssnws1
10.1001/jamapsychiatry.2018.1941,Psychology_easy_381,"Researchers found a strong connection between the dorsolateral prefrontal cortex (responsible for short-term memory), the precuneus (linked with ideas of the self) and the lateral orbitofrontal cortex (associated with negative emotions).",The Shen atlas areas with functional connectivities related to sleep quality.,"Researchers found a strong connection between the dorsolateral prefrontal cortex (responsible for short-term memory), the precuneus (linked with ideas of the self) and the lateral orbitofrontal cortex (associated with negative emotions). An analysis of the records of 9,735 people living with depressive problems found that there was increased activity between these brain regions in people who also reported disrupted sleep patterns, and that's a crucial discovery in our understanding of these conditions. ""These findings provide a neural basis for understanding how depression relates to poor sleep quality, and this in turn has implications for treatment of depression and improvement of sleep quality because of the brain areas identified.""","eFigure 4. The Shen atlas areas with functional connectivities related to sleep quality. There were 162 such links significant with NBS correction, p<0.05.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34644678837&p=1pl&v=1&x=NPMHP58RsDT7VzhGCx19YA
10.1093/jcr/ucw012,Psychology_easy_382,"""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says.",This may have inflated effect sizes relative to a real-world scenario in which not all participants correctly identity a behaviorally targeted ad as such.,"Her study's findings imply that visual distractions -- like the ones caused by the flash of a ""new message"" alert or a news update -- might distort a person's memory of an event or interaction without that person realizing it. ""Even when you think you're focused on a task and performing it, having a distractor that captures your attention very briefly can fundamentally change what you thought you were perceiving,"" she says. ""Consumers who knew they had received a targeted ad reported being more interested in the advertised product, and even changed their self-perceptions to be more in line with what the ad implied about them.""","We also note that the results of this study reflect only those participants who correctly identified whether the ad they were shown was behaviorally targeted. This may have inflated effect sizes relative to a real-world scenario in which not all participants correctly identity a behaviorally targeted ad as such. However, effect sizes are likely to have also been lowered relative to a completely naturalistic setting because we do not use actual targeting software and instead show all participants the same ad.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1001/jamapsychiatry.2018.1941,Psychology_easy_383,"So, whatever it is you're going through, remember you're not alone.","Most participants were healthy controls, and the depressive score was used as an indicator of depressive symptoms, not formal diagnosis; however, we did demonstrate a high correlation between the Depressive Problems score and whether a person had at some time been diagnosed with depression.","The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments."" So, whatever it is you're going through, remember you're not alone.","Several limitations are considered. Most participants were healthy controls, and the depressive score was used as an indicator of depressive symptoms, not formal diagnosis; however, we did demonstrate a high correlation between the Depressive Problems score and whether a person had at some time been diagnosed with depression. We note that there is a strong association between depression and poor sleep, in that the correlation found in this study between the Depressive Problems score and PSQI score was high (r = 0.371, P <1.0×10 −10 , Figure 1B) ; however, this does not address the directionality of the association, which could be in both directions.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1007/s13524-014-0321-x,Psychology_easy_384,"Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children.",These differences may be moderated by the welfare state.,"The increase in parental happiness surrounding the birth of a third child is negligible. Mikko Myrskyla, professor of demography at LSE and Director of the Max Planck Institute for Demographic Research in Rostock, Germany, said: ""Our results show a temporary and transitory gain in parents' happiness around the birth of first and second children. ""The fact that parental happiness increases before these children are born suggests that we are capturing broader issues relating to childbearing such as couples forming partnerships and making plans for the future.","However, parents who already have children may be more confident in their skills and may be better able to cope with children, which would predict that parents' happiness response is more positive for higher-order births. These differences may be moderated by the welfare state. The differences in outof-wedlock childbearing and public support to parents may result in greater differences in parental well-being by marital status in Britain than in Germany.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/10/141028082454.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0956797617692041,Psychology_easy_385,The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means.,"These were qualified by a significant interaction between portion limit and drink size, F(2, 335) = 15.42, p < .001 (Fig.","""Our research provides insight into the effectiveness of a portion limit policy,"" explains behavioral scientist Leslie John of Harvard Business School, first author on the research. The regulation was ultimately overturned but it generated heated debate about the appropriateness and effectiveness of addressing public health issues through such means. The results showed that bundling seemed to diminish participants' interest in buying the larger option: People were less likely to buy a large drink when it was bundled than when it was presented as one serving.","There were significant main effects of portion limit, F(2, 335) = 10.37, p < .001, and drink size, F(1, 335) = 126.59, p < .001. These were qualified by a significant interaction between portion limit and drink size, F(2, 335) = 15.42, p < .001 (Fig. Follow-up tests revealed that for the medium drink, consumption was similar across service styles, F(2, 197) = 1.07, p = .34.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1007/s40519-017-0414-9,Psychology_easy_386,"Questions around mental health showed high rates of depression and stress among the group, and anxiety levels were higher still.","Most frequently they perform: solo (46.9%), within small group (55.8%), within large group (32.3%), other (4.7%).","After analysing the questionnaire data, the researchers revealed almost one-third of the group (32.3%) reported having experienced an eating disorder, a higher proportion than the estimated 1.6 million adults thought to be affected in the UK. Questions around mental health showed high rates of depression and stress among the group, and anxiety levels were higher still. Dr Kapsetaki explained that the demand to perform and to look the part may also add to the stress of musicians, adding: ""These pressures can also lead to anxiety and depression which are risk factors for eating disorders.""","The stages they were in their musical careers were: music students (37.3%), music teachers (36%), professional performers (36.3%), amateur performers (35.6%), other (9.6%). Most frequently they perform: solo (46.9%), within small group (55.8%), within large group (32.3%), other (4.7%). The global score of the EDE-Q mean and SD was 1.67 ± 1.43 (17 musicians did not complete the EDE-Q so their EDE-QGS could not be calculated) and the specific items of EDE-Q: restraint (1.49 ± 1.60), eating concern (0.99 ± 1.29) (16 musicians did not answer all the restraint and eating concern questions), shape concern (2.28 ± 1.75) (14 musicians did not answer this category of questions), weight concern (1.95 ± 1.66) (15 musicians did not answer this category of questions).",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/musicians-have-high-prevalence-of-eating-disorders-study-finds/
10.1177/0963662516629749,Psychology_easy_387,So many of us working in conservation were drawn in through watching Sir David Attenborough's other films as children.,"While it would be naïve to suggest that curriculum reform is a simple process, an approach to the lagging levels of public support for science that focuses on education enjoys at least one key advantage; it promises to be a largely bipartisan effort, at least relative to other approaches that might target values or employ persuasive messaging.","Perhaps the pure and unsullied vision is what makes them so popular. So many of us working in conservation were drawn in through watching Sir David Attenborough's other films as children. and the mind-boggling behaviours of birds (such as the manakins shown doing a shuffle dance), Our Planet will engage a whole new generation.","This approach also has the added benefit of working within the confines of established infrastructure, the education system. While it would be naïve to suggest that curriculum reform is a simple process, an approach to the lagging levels of public support for science that focuses on education enjoys at least one key advantage; it promises to be a largely bipartisan effort, at least relative to other approaches that might target values or employ persuasive messaging. In an era where science is becoming increasingly contentious politically, curriculum reform that is designed to produce a more educated citizenry represents an area of common ground for virtually all actors in the policy making process.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38943467568&p=1pl&v=1&x=9SwgtGU7Zgermm7GUNo8gA
10.1080/08870446.2013.818674,Psychology_easy_389,Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good.,The analysis of the region of significance by the Johnson Neyman technique showed that the simple slopes were significant only at levels of social support higher than 1.86 (p < .05).,"Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette). Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good. When occurring on their own, self-efficacy, coping strategies and social support did not increase the chances of quitting.","Again, the interaction of volitional self-efficacy and smoking-specific received social support was significant (p< .05, see Figure 2 ). The analysis of the region of significance by the Johnson Neyman technique showed that the simple slopes were significant only at levels of social support higher than 1.86 (p < .05). In sum, the results indicate that those individuals who reported high levels of smoking-specific received social support were more likely to be abstinent, the higher their volitional self-efficacy was, indicating a synergistic effect of smoking-specific received social support and volitional selfefficacy.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1007/s00213-014-3810-0,Psychology_easy_390,It's important to note that the idea of Leaky Gut Syndrome is debated in the medical community.,The increase of positive compared to negative emotional information processing in the B-GOS group provides initial evidence that behavioural effects of probiotics in rodent models can be extended to affective processing in humans using prebiotics.,"It's important to note that the idea of Leaky Gut Syndrome is debated in the medical community. Despite this debate, there are a number of symptoms that do co-occur with a ""leaky gut,"" and it's worth paying attention to improving your gut health regardless. If you suspect something is off with your gut health, you should be paying attention to possible symptoms.","b Participants showed decreased attentional vigilance to negative versus positive words in the unmasked condition of the dot-probe task after B-GOS but not FOS intake compared to placebo involuntary deployment of attention ), whereas at longer stimulus durations, it may further involve a difficulty to disengage from salient emotional stimuli . The increase of positive compared to negative emotional information processing in the B-GOS group provides initial evidence that behavioural effects of probiotics in rodent models can be extended to affective processing in humans using prebiotics. These results are also consistent with a recent fMRI study which reported that a 3-week probiotic administration reduced neural response in a network of areas (including the somatosensory cortex, insula and parahippocampal gyrus) to angry and fearful facial expressions .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37981349160&p=1pl&v=1&x=imXPs47SkSTZYADat-Psgw
10.1001/jamapsychiatry.2018.1941,Psychology_easy_391,"Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments.""","However, for the following reasons, we chose to use the Shen atlas rather than HCP atlas.","The crossover here goes some way to proving that sleep and depression are affected by similar parts of our brains a and suggests it is this link that causes us to feel down and more susceptible to mental health problems when we suffer from a lack of sleep. Jianfeng Feng and Edmund Rolls, who headed up the study, stressed the significance of their conclusions to Sleep Review, with Rolls stating that the results are likely to have ""implications for a deeper understanding of depression,"" as the evidence highlights ""a key brain area that might be targeted in the search for treatments."" So, whatever it is you're going through, remember you're not alone.","The AAL2 atlas is available with MRIcron (http://people.cas.sc.edu/rorden/mricron/). However, for the following reasons, we chose to use the Shen atlas rather than HCP atlas. If we used the HCP atlas in our analysis, it would be difficult to perform this very valuable cross-validation analysis.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34713841918&p=1pl&v=1&x=L0FHu5xHlNT03mTOI2nB8Q
10.1177/0956797617692041,Psychology_easy_392,But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves.,"In the results from this full logistic regression model (which included two main effects and an interaction term), there was therefore no evidence that bundling led to a backfire effect (i.e., bundling did not increase purchasing).","This may have happened, the researchers surmise, because consumers wanted to get their ""money's worth"" - that is, they consumed more of the refill since they had already paid for it. But data from two additional experiments indicate that this unintended increase in consumption can be dampened somewhat by requiring people to get the refills themselves. ""Taken together, these results suggest that this method of complying with a sugary-drink portion limit could have the perverse effect of increasing consumption,"" the researchers write.","However, the participants were marginally significantly less likely to order large drinks in the bundled condition than in the typical-portion condition, OR = 0.59, 95% CI = [0.32, 1.09], p = .09, d = 0.25 ( Fig. In the results from this full logistic regression model (which included two main effects and an interaction term), there was therefore no evidence that bundling led to a backfire effect (i.e., bundling did not increase purchasing). In fact, the result of a χ 2 test comparing only the bundled and typical-portion conditions, collapsed across serving style, was significant: Drink purchasers were 64.8% less likely to buy a large drink in the bundled condition than in the typical-portion condition (25.6% bought a large drink in the bundled condition, and 39.5% bought a large drink in the typical-portion condition), χ 2 (1, N = 362) = 7.90, p = .005.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/some-strategies-to-limit-sugary-drinks-may-backfire/
10.1093/jcr/ucw012,Psychology_easy_393,Some of this research hints at the memory-distorting power of brief visual distractions.,"On one hand, consumers are more interested in information about where they stand on traits and identities that are important to them, which may make the effects of behaviorally targeted ads stronger for important traits .","""Anything less than half full, however, induced feelings of profound anxiety and discomfort."" Some of this research hints at the memory-distorting power of brief visual distractions. When the people in the study were then asked to recall the color of the highlighted square and identify it on a color wheel, the people who had been distracted were much more likely to pick the wrong color.","Additionally, it would be useful to investigate the role of the importance (to the self) of the trait implied from the label ). On one hand, consumers are more interested in information about where they stand on traits and identities that are important to them, which may make the effects of behaviorally targeted ads stronger for important traits . On the other hand, consumers' selfperceptions on traits that are very important to them are arguably less malleable , which may mute these effects.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40338498080&p=1pl&v=1&x=V53CkzJkG1_9kTNpbGkVtQ
10.1038/s41598-017-03627-7,Psychology_easy_395,"""Touch brings it back.""","As in the case of respiratory rate, touch and pain moderated the partners' velocity effect both in women and in men (F (4,25000) = 19.40, p < 0.0001, −ΔBIC = 7.7, ΔR 2 = 0.12), indicating that the partner velocity effect differed across experiment conditions.","""It appears that pain totally interrupts this interpersonal synchronization between couples,"" Goldstein said. ""Touch brings it back."" The more physiologically synchronized they were, the less pain she felt.","However, there was no difference between pain and no pain during both touch (Δζ t(p/np) = 0.004, p = 0.115) and no touch (Δζ nt(p/np) = 0.002, p = 0.637) conditions. As in the case of respiratory rate, touch and pain moderated the partners' velocity effect both in women and in men (F (4,25000) = 19.40, p < 0.0001, −ΔBIC = 7.7, ΔR 2 = 0.12), indicating that the partner velocity effect differed across experiment conditions. (Fig.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39586310183&p=1pl&v=1&x=MLIK2XeMJ34Ijqm2aaBClw
10.1177/0141076814565942,Psychology_easy_396,"""Furthermore, there are many potentially confounding variables which could explain raised ASD rates, which the authors do not explore or account for,"" Turk continued.","Among children operated for a variety of conditions, Levy noted a strong association between the age at operation and the frequency and severity of emotional sequelae.","While this is a valid way of doing a study, it means that we must be careful about any implications,"" he said. ""Furthermore, there are many potentially confounding variables which could explain raised ASD rates, which the authors do not explore or account for,"" Turk continued. ""Finally, I have some issues with the premise in that their speculations regarding early pain as a cause of autism are, to say the least, highly speculative.""","Considering the widespread practice of non-therapeutic circumcision in infancy and childhood around the world, confirmatory studies should be given priority. Among children operated for a variety of conditions, Levy noted a strong association between the age at operation and the frequency and severity of emotional sequelae. Psychological problems were encountered in 4% of children aged < years at the time of operation, as compared with 0% among older children.",[1],Psychology,train,1.0,news,http://www.redorbit.com/news/health/1113311836/does-circumcision-increase-the-risk-of-autism-011115/
10.1080/08870446.2013.818674,Psychology_easy_397,"Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette).","However, as levels of social support increased, attitude became a stronger predictor of intentions showing that as social support increased, the power of attitude to predict intentions increased as well.","Such support could involve their partner reminding them of their plan to quit as well as encouraging and supporting them in critical situations. Careful planning

The same is true of the coping strategies that the smoker plans to apply in difficult situations (for instance, taking a chewing gum or being reminded of one's wish to quit when spending an evening in the company of smokers and feeling an uncontrollable craving for a cigarette). Smokers who plan carefully and -- again -- receive the right kind of support from their partners are more likely to stop for good.","In the latter, perceived social support was positively related to intentions at all levels of attitudes. However, as levels of social support increased, attitude became a stronger predictor of intentions showing that as social support increased, the power of attitude to predict intentions increased as well. This interaction effect indicates a synergistic effect of individual regulation and social support.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/07/130724102602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1186/s13229-018-0246-0,Psychology_easy_398,"This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research.""","After adjusting for the other factors, father's education and father's occupation (higher social status occupations were less likely to take part), and child's age were the strongest factors related to non-response.","This collaboration with colleagues in China is so valuable to help us understand what is universal and what is culture-specific in autism research."" In Jilin City, from a total population of 7,258, the team identified 77 cases of autism, equating to a prevalence of 108 per 10,000, very similar to that found in the West. In Shenzhen and Jiamusi cities, only data for children in mainstream education was available; in Shenzhen City, 42 out of every 10,000 children in mainstream education had autism, and in Jiamusi City this figure was 19 per 10,000.","The following variables were not significantly related to response rate: mother's or father's age, who completed the questionnaire, or mother's occupation. After adjusting for the other factors, father's education and father's occupation (higher social status occupations were less likely to take part), and child's age were the strongest factors related to non-response. In addition, the higher the CAST score the less likely the child was to take part, though this effect was small.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38803711012&p=1pl&v=1&x=__aEa1i_DgRqCsuf6-1kqA
10.1093/jcr/ucw012,Psychology_easy_399,"""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said.",Study 2 sheds light on this process by measuring consumers' self-perceptions.,"While the advertising industry has been reluctant to tout its use of targeted ads because of privacy concerns, this research suggests there may be benefits for companies that indicate to consumers that they are sending ads meant specifically for them. ""If you're a person who goes out hiking occasionally and you see a behaviorally targeted ad for hiking boots that suggests you're rugged and outdoorsy, our results suggest you will feel more outdoorsy and then be more likely to buy that product,"" Reczek said. The study's findings have broader implications beyond advertising, Smith said.","The data also show that the effects of behavioral targeting are not due to differences in liking for the advertisement because consumers liked the ad equally in all conditions. Study 2 sheds light on this process by measuring consumers' self-perceptions. Second, we increase the external validity of our work by manipulating awareness of whether the ad is behaviorally targeted using the industry-standard AdChoices icon.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/KIPqQyrnyiA/
10.1177/0001839213509590,Psychology_easy_400,"Across three studies, well-educated graduates who entered the workforce during economic downturns were happier with their work than those who first searched for jobs during more prosperous times.","Across three studies, well-educated graduates who entered the workforce during economic downturns were more satisfied with their current jobs than those who entered during more prosperous economic times.","Across three studies, well-educated graduates who entered the workforce during economic downturns were happier with their work than those who first searched for jobs during more prosperous times. In fact, they were happier with their jobs both early and late in their careers, even when they earned less money. Author Emile C. Bianchi wrote, ""people who entered the workforce in bad economies were less likely to entertain ... thoughts about how they might have done better, and more likely to feel grateful for their jobs, both of which mediated the relationship between economic conditions at workforce entry and job satisfaction.""","Across three studies, well-educated graduates who entered the workforce during economic downturns were more satisfied with their current jobs than those who entered during more prosperous economic times. Study 1 showed that economic conditions at college graduation predicted later job satisfaction even after accounting for different industry and occupational choices. Study 2 replicated these results and found that recession-era graduates were more satisfied with their jobs both early and later in their careers and even when they earned less money.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/03/140326092631.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/1533317514549411,Psychology_easy_402,"""This may be due to the fact that adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to unfavorable health outcomes.""","This may be due to adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to adverse health outcomes and become abstainers during old age.","In addition, exposing the brain to moderate amounts of alcohol may increase the release of brain chemicals involved with cognitive, or information processing, functions. ""There were no significant differences in cognitive functioning and regional brain volumes during late life according to reported midlife alcohol consumption status,"" said lead author Brian Downer, UTMB Sealy Center on Aging postdoctoral fellow. ""This may be due to the fact that adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to unfavorable health outcomes.""","There were no significant differences in cognitive functioning and regional brain volumes during late life according to midlife alcohol consumption status. This may be due to adults who are able to continue consuming alcohol into old age are healthier, and therefore have higher cognition and larger regional brain volumes, than people who had to decrease their alcohol consumption due to adverse health outcomes and become abstainers during old age. There also may be an accumulative effect of alcohol consumption on cognitive functioning and regional brain volumes, meaning a person needs to consume alcohol, but not abuse alcohol, for several years or even decades before differences in cognitive functioning and regional brain volumes are observed.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141023092031.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1016/j.brat.2017.09.010,Psychology_easy_403,"""Mindfulness research in general could benefit from employing the SOBC experimental medicine approach,"" she said.",Mindfulness research in general could benefit from employing the SOBC experimental medicine approach.,"Britton said the SOBC approach can make mindfulness more effective for people who practice it. ""Mindfulness research in general could benefit from employing the SOBC experimental medicine approach,"" she said. The SOBC experimental medicine approach will not only help MBIs become maximally effective, but also provide essential mechanistic information that will help tailor the intervention and instructor training to specific populations and conditions.""","Verification of target engagement with different assays of attention control and emotional non-reactivity, including behavioral, neuroimaging and peripheral biological assays, will promote cross-validation of reliable target engagement. Mindfulness research in general could benefit from employing the SOBC experimental medicine approach. The SOBC experimental medicine approach will not only help MBIs become maximally effective, but also provide essential mechanistic information that will help tailor the intervention and instructor training to specific populations and conditions.",[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/researchers-dismantle-mindfulness-intervention-to-see-how-each-component-works/
10.1038/s41598-018-25951-2,Psychology_easy_404,The illusory body ownership was rated higher when the virtual gloves and socks moved synchronously with their own movements than the asynchronous condition.,Participants (n = 20) rated the illusory body ownership higher when the virtual gloves and socks moved synchronously with their own movements than the asynchronous condition (Q1 in Fig.,"It can provide the illusory ownership over the invisible body at a distance, or enable the operation of one's own transparentized body in a virtual environment. The illusory body ownership was rated higher when the virtual gloves and socks moved synchronously with their own movements than the asynchronous condition. They felt as if their own had become increasingly transparent when the motion was synchronized as compared to when the motion was asynchronized.","When illusory body ownership occurs with the virtual invisible body in front of the participant, self-location will drift toward the virtual invisible body similar to the full-body ownership illusion 7 . Participants (n = 20) rated the illusory body ownership higher when the virtual gloves and socks moved synchronously with their own movements than the asynchronous condition (Q1 in Fig. The feeling of proprioceptive drift toward the invisible body was higher in the synchronous than the asynchronous condition (Q2).",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34067160300&p=1pl&v=1&x=niuTnjuk6xovRc22fgXc3w
10.1027/1864-9335/a000198,Psychology_easy_406,"""The present results demonstrate that patterns of general action may occur for reasons other than the desire to be active versus inactive,"" the researchers wrote.","Prior research has not made this distinction, but the present results demonstrate that patterns of general action may occur for reasons other than the desire to be active versus inactive.","Thus, compared with likers, haters could be characterized as less active because they do fewer things, or they could be characterized as more focused because they spend more time on the small number of things they do. ""The present results demonstrate that patterns of general action may occur for reasons other than the desire to be active versus inactive,"" the researchers wrote. ""Indeed, some people may be more active than others not because they want to be active per se, but because they identify a large number of specific behaviors in which they want to engage.""","However, some people may be more active than others not because they want to be active per se but because they identify a large number of specific behaviors in which they want to engage. Prior research has not made this distinction, but the present results demonstrate that patterns of general action may occur for reasons other than the desire to be active versus inactive. In this vein, it is possible that completing a time use survey could prime a self-concept related to dispositional attitudes, and participants may consequently change their DAM responses after this concept is primed; as the present research did not restrict participants from modifying survey responses after completing each form, the present studies cannot rule out this possibility.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/06/140619125419.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1001/jamaophthalmol.2018.5527,Psychology_easy_408,"Further, a lower self-perception of scholastic competence was associated with a slower reading speed, and a lower self-perception of scholastic, social, and athletic competence was associated with worse performance of aiming and catching among children with amblyopia.","Among children with amblyopia, the self-perception of scholastic competence was associated with reading speed, and the self-perception of scholastic, social, and athletic competence was associated with aiming and catching skills.","The researchers found that children with amblyopia had significantly lower scores than control children on the scholastic, social, and athletic competence domains of the Self-Perception Profile for Children. Further, a lower self-perception of scholastic competence was associated with a slower reading speed, and a lower self-perception of scholastic, social, and athletic competence was associated with worse performance of aiming and catching among children with amblyopia. There were no significant differences between the groups regarding the self-perception of physical appearance or global self-worth.","In this cross-sectional study, children with amblyopia had lower scholastic, social, and athletic competence scores as derived from the Self-perception Profile for Children than control children. Among children with amblyopia, the self-perception of scholastic competence was associated with reading speed, and the self-perception of scholastic, social, and athletic competence was associated with aiming and catching skills. These results suggest lower self-perception and its association with reading speed and motor skills highlight the potentially wide-ranging influence of altered visual development in children in their everyday lives.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=37826068637&p=1pl&v=1&x=KCq3Gf4J_kPWNf9-eWLZTQ
10.1098/rspb.2013.1724,Psychology_easy_409,"However, the results were completely opposite: for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow.","However, we did find that, for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow.","The bolder fish was also rewarded every time it followed the shyer member, but not when it emerged from safe cover by itself. However, the results were completely opposite: for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow. The bold fish readily adapted to following but the shy fish could not be trained to lead, even when it learnt to stop following the other fish.","Contradicting the predictions outlined in the Introduction , we did not find any difference in the adaptability of bold and shy individuals to changes in leadership. However, we did find that, for both bold and shy individuals, the tendency to lead is much less flexible than the tendency to follow. The tendency to initiate trips differed only between treatments by 27% in bold and 46% in shy fish (figure 3a; q 12 /q In summary, fish (whether bold or shy) can easily learn to follow, but they cannot easily learn to lead.",[5],Psychology,train,5.0,news,http://www.scientificamerican.com/article.cfm?id=leaders-are-born-not-made-fish-study-finds
10.1177/0956797613514092,Psychology_easy_410,"The scholars claimed that, according to their theory, ""there is no reason why people lacking resources should make harsher judgments of non-harmful transgressions.""","Thus, according to our theory, there is no reason why people lacking resources should make harsher judgments of non-harmful transgressions.","Statistical analysis demonstrated that both parameters are statistically associated with stronger value judgments. The scholars claimed that, according to their theory, ""there is no reason why people lacking resources should make harsher judgments of non-harmful transgressions."" Predictions of the theory were empirically supported.","For instance, regardless of the amount of resources a person has, this person will be similarly vulnerable to witnessing someone's indecent behavior in public. Thus, according to our theory, there is no reason why people lacking resources should make harsher judgments of non-harmful transgressions. If our explanation is correct, lack of material resources should only affect judgments of harmful, but not non-harmful transgressions.",[5],Psychology,train,5.0,news,http://www.technology.org/2014/04/04/lack-material-resources-causes-harsher-moral-judgments/
10.1007/s00038-016-0900-2,Psychology_easy_411,Those rating communication with their mother as 'difficult' have 2.47 times greater odds of reporting self-harm than those who rated their communication as 'easy'.,Those rating communication with their father as ''difficult'' were estimated to have 2.14 times greater odds of reporting self-harm than those who rated their communication as ''easy'' (,"Those with low 'school sense of belonging' (SSB) have 6.70 times greater odds of reporting self-harm as those with high SSB, and 3.16 times greater odds than those with medium SSB. Those rating communication with their mother as 'difficult' have 2.47 times greater odds of reporting self-harm than those who rated their communication as 'easy'. Those rating communication with their father as 'difficult' have 2.14 times greater odds of reporting self-harm than those who rated their communication as 'easy'.",Those rating communication with their mother as ''difficult'' were estimated to have 2.47 times greater odds of reporting self-harm than those who rated their communication as ''easy'' (Table 2; Figs. Those rating communication with their father as ''difficult'' were estimated to have 2.14 times greater odds of reporting self-harm than those who rated their communication as ''easy'' ( Those with Low NSB are estimated to have 2.84 times greater odds of reporting self-harm as those with High NSB.,[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/young-people-seven-times-more-likely-to-self-harm-if-their-sense-of-belonging-to-school-is-low/
10.1093/schbul/sbx158,Psychology_easy_413,The findings suggest frequent adolescent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder.,"Consistent with the stage specific model of mental disorders linking intervention to stage of illness, our findings suggest frequent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder.","Cannabis use was also found to mediate the association of both childhood sexual abuse and hypomania, and male gender and hypomania. The findings suggest frequent adolescent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder. Commenting on the research, Dr Marwaha said:

""Cannabis use in young people is common and associated with psychiatric disorders.","The study also identifies cannabis use as a candidate mechanism for explaining how childhood abuse may lead to hypomania in adulthood. This is important in the context of the push in many jurisdictions to legalize or decriminalize cannabis. Consistent with the stage specific model of mental disorders linking intervention to stage of illness, our findings suggest frequent cannabis use is likely to be a suitable target for interventions that may allay the risk of young people developing bipolar disorder.",[5],Psychology,train,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/xJezh05NVH4/
10.1001/jamapsychiatry.2017.4249,Psychology_easy_415,"""Our findings that WET is as efficient and efficacious as CPT for PTSD may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers,"" study corresponding author Denise Sloan said in a university news release.",The findings suggest that WET is an efficacious and efficient PTSD treatment that may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers.,"Of these patients, 63 were randomly assigned to received WET and 63 received CPT. The investigators found that five sessions of written exposure therapy was just as effective as 12 sessions of cognitive processing therapy for people with post-traumatic stress. ""Our findings that WET is as efficient and efficacious as CPT for PTSD may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers,"" study corresponding author Denise Sloan said in a university news release.","CONCLUSIONS AND RELEVANCE Although WET involves fewer sessions, it was noninferior to CPT in reducing symptoms of PTSD. The findings suggest that WET is an efficacious and efficient PTSD treatment that may reduce attrition and transcend previously observed barriers to PTSD treatment for both patients and providers. 3 Also included in this recommended group of treatments is written narrative exposure, which the clinical practice guideline notes is a simple, yet effective, way to deliver exposure therapy for PTSD.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33137979213&p=1pl&v=1&x=LXzHX7g0EiQbzRCS8xg_rw
10.1080/16066359.2017.1311877,Psychology_easy_416,"By contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana.","In contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana (5.3 ± 2.7, t (199) ¼ 1.7, p ¼ .09).","But both alcohol and marijuana users reported increased pleasure from smoking cigarettes when drinking alcohol - and this pleasure was not heightened by binge drinking. By contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana. Findings Could Help People Cope With Smoking Triggers

""Our findings point to different reasons why people co-use cigarettes with marijuana than with alcohol,"" said Johannes Thrul, PhD, co-first author of the study and a postdoctoral scholar at the UCSF Center for Tobacco Control Research and Education.","Individuals reported an increase in perceived pleasure from smoking cigarettes when drinking alcohol (7.0 ± 2.2 versus null hypothesis 5 ¼ ""no increase or decrease in pleasure""; t (199) ¼13.0, p < .001). In contrast, there was on average no change in perceived pleasure from smoking cigarettes when using marijuana (5.3 ± 2.7, t (199) ¼ 1.7, p ¼ .09). Perceived pleasure from smoking cigarettes did not differ by frequency of binge drinking (F (3,200) ¼ 0.84, p ¼ .47): nonbinge (7.1 ± 2.1), 1-3 binge days (6.8 ± 2.3), 4-8 binge days (7.0 ± 2.1), 9 þ binge days (7.6 ± 2.2).",[5],Psychology,train,5.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/shliui9I8xg/
10.1152/jn.00839.2014,Psychology_easy_418,"""Therapies that help to maintain peripheral nerve function, such as the peripheral nerve stimulation paradigm used in the current study, need to be incorporated into the mainstream neuro-rehabilitation program in the early phases of SCI,"" the researchers wrote.","Second, therapies that help to maintain peripheral nerve function (such as the peripheral nerve stimulation paradigm used in the current study) need to be incorporated into the mainstream neurorehabilitation program in the early phases of SCI.","According to the researchers, short-term peripheral nerve stimulation may be a new approach to preventing long-term changes in nerve and muscle function and improving rehabilitation outcomes. ""Therapies that help to maintain peripheral nerve function, such as the peripheral nerve stimulation paradigm used in the current study, need to be incorporated into the mainstream neuro-rehabilitation program in the early phases of SCI,"" the researchers wrote. It is highlighted as one of this month's ""best of the best"" as part of the American Physiological Society's APSselect program.","First, assessment of peripheral nerve function must commence in the acute phase of SCI and needs to be investigated routinely, especially in patients with complaints of new motor weakness, sensory loss, or pain. Second, therapies that help to maintain peripheral nerve function (such as the peripheral nerve stimulation paradigm used in the current study) need to be incorporated into the mainstream neurorehabilitation program in the early phases of SCI. Last, peripheral nerve stimulation may be used as a preventative strategy to maintain neural function in peripheral nerves that are more prone to chronic compression, such as the median and ulnar nerves at the wrist and elbows, as well as the CPN near the fibula head and the posterior tibial nerve in the popliteal fossa.",[5],Psychology,train,5.0,news,http://www.newswise.com/articles/electrical-nerve-stimulation-can-reverse-spinal-cord-injury-nerve-damage-in-patients
10.1111/add.12373,Psychology_easy_419,But the relationship between societal and family affluence and cannabis use appears to be changing.,"However, gender patterns of consumption and the relationship between societal and family affluence and cannabis use may be changing.","But the relationship between societal and family affluence and cannabis use appears to be changing. The overall results showed a significant decline in cannabis use. Affluent countries in Western and Southern Europe and North America (Belgium, Canada, Denmark, France, Germany, Ireland, Italy, Netherlands, Portugal, Spain, the United Kingdom, USA) showed a decrease in frequent cannabis consumption among 15-year-old boys and/or girls.","However, gender patterns of consumption and the relationship between societal and family affluence and cannabis use may be changing. Across geographical areas and time, adolescent males report higher prevalence of cannabis use compared to females and a greater tendency to abuse and develop dependence on cannabis . Two cultural trends worked in the same direction.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2013/11/131122084539.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1098/rspb.2013.2661,Psychology_easy_420,The behavior acts as a signal to others in the neighborhood that non-cooperation will not be tolerated.,The behaviour acts as a signal to potential co-players in the neighbourhood that non-cooperation will not be tolerated.,"The results suggest when responsible third-party punishment evolves, it does so because the responsible punishers' actions are ultimately not altruistic. The behavior acts as a signal to others in the neighborhood that non-cooperation will not be tolerated. The results also show that responsible third-party punishment does not evolve in populations with weak social ties or high mobility.","When responsible 3PP evolves, it does so as an ultimately non-altruistic trait. The behaviour acts as a signal to potential co-players in the neighbourhood that non-cooperation will not be tolerated. High strength-of-ties and low mobility allow clustered agents engaging in responsible 3PP to induce cooperation in their neighbourhood.",[5],Psychology,train,5.0,news,http://www.technology.org/2013/12/11/game-theory-used-explain-evolution-third-party-punishment/
10.1177/0361684315581169,Psychology_easy_421,"""Women may also reason that other people can neither change their infertility status nor understand what they were experiencing,"" Ceballo says.",Women may reason that other people can neither change their infertility status nor understand what they were experiencing.,"Some women, especially those with secondary infertility, stayed silent about being unable to conceive because discussing it did not elicit sympathy or empathy. ""Women may also reason that other people can neither change their infertility status nor understand what they were experiencing,"" Ceballo says. The women may stay silent about their infertility because of cultural expectations about strong, self-reliant black women who can cope with adversity on their own and with notions about maintaining privacy in African-American communities, Ceballo says.","Moreover, because pregnancy is visibly located in women's bodies, women may be more likely than men to feel ashamed and to blame themselves for infertility. Women may reason that other people can neither change their infertility status nor understand what they were experiencing. In our sample, this sentiment was especially true for women who were struggling with secondary infertility.",[5],Psychology,train,5.0,news,http://www.futurity.org/african-american-women-infertility-937582/
10.1126/science.1152408,Psychology_easy_422,"Authors Jeffrey D. Karpicke and Henry L. Roediger III explain:

Repeated studying after learning had no effect on delayed recall, but repeated testing produced a large positive effect.","Repeated studying after learning had no effect on delayed recall, but repeated testing produced a large positive effect.","There's a reason why practice tests are so effective. Authors Jeffrey D. Karpicke and Henry L. Roediger III explain:

Repeated studying after learning had no effect on delayed recall, but repeated testing produced a large positive effect. In addition, students' predictions of their performance were uncorrelated with actual performance.","Repeated studying after learning had no effect on delayed recall, but repeated testing produced a large positive effect. In addition, students' predictions of their performance were uncorrelated with actual performance. The results demonstrate the critical role of retrieval practice in consolidating learning and show that even university students seem unaware of this fact.",[5],Psychology,train,5.0,news,http://lifehacker.com/boost-your-memory-by-testing-yourself-not-re-reading-1669460051
10.1038/s41598-018-27126-5,Psychology_easy_424,"""Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education.""",Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education.,"According to the results, published in Scientific Reports, music playschool significantly improved the development of children's phoneme processing and vocabulary skills, compared to their peers either attending to similarly organized dance lessons or not attending to either activity. ""Our data suggest that even playful group music activities -- if attended to for several years -- have a positive effect on preschoolers' linguistic skills,"" says the first author of the research, Tanja Linnavalli. ""Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education.""","Our data suggest that even playful group music activities -if attended to for several years -have a positive effect on pre-schoolers' linguistic skills. Therefore we promote the concept of implementing regular music playschool lessons given by professional teachers in early childhood education. Musicians outperform non-musicians in syllable discrimination 1 and in detecting speech in noise 2,3 .",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34278185355&p=1pl&v=1&x=TwmXeJQnRrW6DAQ9nqmDtA
10.1073/pnas.1517057112,Psychology_easy_425,"The study's findings, however, suggest ""power-disadvantaged actors effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions.""","Power-disadvantaged actors thus effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions.","These results contradict predictions derived from ""rational actor"" models, Cook says. The study's findings, however, suggest ""power-disadvantaged actors effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions."" Their hope that their powerful partners will be trustworthy dominates their cognition and decision-making, in support of motivated cognition theory, says the researchers.","In particular, with increasing dependence, people will be motivated to see their partner as more trustworthy to avoid the anxiety inherently attached to their feelings of dependence. Power-disadvantaged actors thus effectively protect themselves by perceiving power holders in a positive light, even if little or no relevant information would support such perceptions. Using different experimental paradigms and measures and confirming predictions based on motivated cognition theory, we show that people low in power are significantly more trusting than more powerful people and that this effect can be explained by the constructs of hope and perceived benevolence.",[5],Psychology,train,5.0,news,http://www.futurity.org/power-trust-1055402-2/
10.1186/2193-7680-3-1,Psychology_easy_426,"""This has clear policy implications for policing these settings and highlights the importance of joint operations and information-sharing between transit agencies and local police forces.""",This has clear policy implications for policing these settings and highlights the importance of joint operations and information sharing between transit agencies and local police forces operating near major transit systems.,"""The findings suggest that offenders who operate below ground may also operate above ground on major transit systems,"" writes Dr Newton. ""This has clear policy implications for policing these settings and highlights the importance of joint operations and information-sharing between transit agencies and local police forces."" It might not be until the end of the journey that you realise you have been a victim.""","The findings suggest offenders who operate below ground may also operate above ground on major transit systems. This has clear policy implications for policing these settings and highlights the importance of joint operations and information sharing between transit agencies and local police forces operating near major transit systems. Four potential settings of theft are identified; in the vicinity of a station but outside its boundary; inside a station boundary before the paid access barrier; within the paid access barrier outside of carriages, and; inside a rail carriage.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/04/140404140033.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0963721418763931,Psychology_easy_428,"""Stripped of context, standalone statistics may simply be used as 'evidence' of the stereotype that blacks are prone to criminality,"" the researchers write.","Stripped of context, stand-alone statistics may simply be used as ""evidence"" of the stereotype that Blacks are prone to criminality.","They suggest providing other background information, like the fact that African Americans make up 28 percent of the city's population or that African Americans are stopped for less severe traffic offenses than whites are. ""Stripped of context, standalone statistics may simply be used as 'evidence' of the stereotype that blacks are prone to criminality,"" the researchers write. It is important to offer information about the history of these disparities in the U.S. and how they came about, which might help convey that racial inequality is not natural or due to fixed stereotypical traits, the researchers said.","Future research should test whether a more effective way to frame inequality might be to present information about disparities alongside a description of how those disparities came to be. Stripped of context, stand-alone statistics may simply be used as ""evidence"" of the stereotype that Blacks are prone to criminality. Exposure to information about racial disparities in the criminal justice system may activate and strengthen implicit associations linking Blacks with crime, violence, threat, and aggression.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34130241401&p=1pl&v=1&x=snmpzt5kdVSv2Tv9srGriA
10.1002/hbm.22441,Psychology_easy_430,"In a cohort of 85 subjects (all males, ages 15-55 years), we show very high correlation between age and ""heterogeneity"" (a measure of structural layout of tissue in a region-of-interest) in specific brain regions.","In a cohort of 85 subjects (all males, ages 15-55 years), we show very high correlation between age and ""heterogeneity"" (a measure of structural layout of tissue in a region-of-interest) in specific brain regions.","In a cohort of 85 subjects (all males, ages 15-55 years), we show very high correlation between age and ""heterogeneity"" (a measure of structural layout of tissue in a region-of-interest) in specific brain regions. Our findings from dMRI data connects the functional and structural domains and confirms the ""retrogenesis"" hypothesis of gray matter alterations while lending support to the neurofunctional PASA model of aging in addition to showing the preservation of paralimbic areas during healthy aging.","In a cohort of 85 subjects (all males, ages 15-55 years), we show very high correlation between age and ""heterogeneity"" (a measure of structural layout of tissue in a region-of-interest) in specific brain regions. Our findings from dMRI data connects the functional and structural domains and confirms the ""retrogenesis"" hypothesis of gray matter alterations while lending support to the neurofunctional PASA model of aging in addition to showing the preservation of paralimbic areas during healthy aging. Specifically, fMRI is a useful imaging modality that can capture resting state as well as task specific activation of neural processes in the cortical and sub-cortical areas of the brain.",[5],Psychology,train,5.0,news,http://www.technology.org/2014/01/04/gray-matter-alterations-early-aging-diffusion-magnetic-resonance-imaging-study/
10.1001/jamapsychiatry.2017.4271,Psychology_easy_431,"""Our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use,"" the authors write.","CONCLUSIONS AND RELEVANCE In this study, our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use.","The researchers found strong evidence that early-onset cigarette-only use, early-onset cannabis use, and late-onset cannabis use were correlated with increased psychotic experiences compared with nonuse before adjustment for a range of potential confounders. The association for early-onset cigarette-only use was attenuated substantially after adjustment for confounders (unadjusted odds ratio, 3.03 [95 percent confidence interval, 1.13 to 8.14]; adjusted odds ratio, 1.78 [95 percent confidence interval, 0.54 to 5.88]); for early-onset cannabis use and late-onset cannabis use, the correlations remained consistent (adjusted odds ratios, 3.7 [95 percent confidence interval, 1.66 to 8.25] and 2.97 [95 percent confidence interval, 1.63 to 5.4], respectively). ""Our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use,"" the authors write.","After adjusting for confounders, the association for early-onset cigarette-only use attenuated substantially (unadjusted odds ratio [OR], 3.03; 95% CI, 1. adjusted OR, 1.78; 95% CI,), whereas those for early-onset cannabis use (adjusted OR, 3.70; 95% CI, 1.66-8.25) and late-onset cannabis use (adjusted OR, 2.97; 95% CI, 1.63-5.40) remained consistent. CONCLUSIONS AND RELEVANCE In this study, our findings indicate that while individuals who use cannabis or cigarettes during adolescence have an increased risk of subsequent psychotic experiences, epidemiological evidence is substantively more robust for cannabis use than it is for tobacco use. Individuals who use cannabis regularly have a 2-to 3-fold increased risk of a psychotic outcome.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33045699177&p=1pl&v=1&x=ZYNIJXut-stan-bbWjiCOw
10.1001/jamapsychiatry.2014.1600,Psychology_easy_432,"Despite the distress elicited by engaging with memories of the death, this strategy does not lead to aversive responses.","Despite the distress elicited by engaging with memories of the death, this strategy does not lead to aversive responses.","Fewer patients in the CBT/exposure group at follow-up (14.8 percent) met the criteria for PGD than those in the group who received CBT alone (37.9 percent). ""In the most valuable lesson from this study, optimal gains with PGD patients are achieved when the emotions associated with the memories of the death and the sequelae of the loss are fully accessed. Despite the distress elicited by engaging with memories of the death, this strategy does not lead to aversive responses.","In the most valuable lesson from this study, optimal gains with PGD patients are achieved when the emotions associated with the memories of the death and the sequelae of the loss are fully accessed. Although focusing on appraisals and developing future directions apparently was somewhat beneficial, directing patients to access their emotional memories appears to achieve the most effective outcomes. Despite the distress elicited by engaging with memories of the death, this strategy does not lead to aversive responses.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141022163931.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1001/jamapsychiatry.2014.3028,Psychology_easy_433,"""We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in U.K. twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences,"" the study concludes.",We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in UK twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences.,"The authors found that on all ASD measures, associations among monozygotic (identical) twins were higher than those for dizygotic (fraternal) twins, resulting in heritability estimates of 56 percent to 95 percent. The analyses highlight the importance of genetic factors in the cause of ASD along with moderate non-shared (different experiences among children in the same families) environmental influences, according to the study. ""We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in U.K. twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences,"" the study concludes.",The present study combines the strengths of previous studies and provides a more complete picture than any of them individually by being nationally representative and incorporating dimensional and categorical measures using a systematic repeated screening method. We conclude that liability to ASD and a more broadly defined high-level autism trait phenotype in UK twins 8 years or older derives from substantial genetic and moderate nonshared environmental influences. Genetic influences on diagnosed ASD are shared with those on autistic traits in the general population.,[5],Psychology,train,5.0,news,http://www.science20.com/news_articles/twins_study_tries_to_determine_heritability_of_autism_spectrum_disorder-153725
10.1001/jamapsychiatry.2018.0747,Psychology_easy_434,"""These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease,"" the authors write.",These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease.,"In the opposite pathway, linking visit 1 BDI score with HRV at visit 2, the magnitude of the correlation was similar; this correlation was mainly explained by antidepressant use. For the path linking visit 1 HRV with visit 2 BDI score, significant correlations were seen in monozygotic and dizygotic twins; the correlations were slightly stronger in dizygotic twins. ""These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease,"" the authors write.",The opposite causal pathway from depression to lower HRV is mostly driven by antidepressant use. These findings highlight an important role of autonomic nervous system in the risk of depression and contribute new understanding of the mechanisms underlying the comorbidity of depression and cardiovascular disease. Reduced HRV is a marker of decreased ANS flexibility and may reflect an increase in the sympathetic nervous system and/or a decrease in the parasympathetic nervous system modulation.,[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34106030332&p=1pl&v=1&x=kJ9GF8HlJv6FfMId5-CXNg
10.1038/s41598-018-30798-8,Psychology_easy_435,Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age.,Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age.,"Adults and older children were more easily influenced by vision. Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age. Rebecca said: ""Our findings show that children rely more on auditory information.","adults and older children were more easily influenced by vision). Reduced susceptibility in childhood supports the theory that sensory dominance shifts across development and reaches adult-like levels by 10 years of age. The McGurk effect exemplifies this, as hearing a voice say ""Ba"" and seeing a face say ""Ga"" often results in perception of an alternative syllable such as ""Da"" or ""Tha"" 1 .",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34878459875&p=1pl&v=1&x=YLH01xEfMS5U0R9xMz9EEw
10.1001/jamapsychiatry.2017.4277,Psychology_easy_436,"""Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders,"" the authors write.","CONCLUSION AND RELEVANCE Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders.","Across a range of clinical domains and cognitive test scores, this feature's transdiagnostic importance was confirmed with univariate analysis. Both the general psychopathology (16 percent; P = 0.05) and cognitive factor (18 percent; P = 0.01) were heritable, with a negative genetic correlation. ""Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders,"" the authors write.","Both the general psychopathology (16%; SE, 0.095; P = .05) and cognitive (18%; SE, 0.09; P = .01) factor were heritable and showed a negative genetic correlation. CONCLUSION AND RELEVANCE Dimensional and heritable general cognitive and psychopathology factors are associated with specific patterns of white matter properties, suggesting that dysconnectivity is a transdiagnostic brain-based phenotype in individuals with increased susceptibility and symptoms of psychiatric disorders. Whereas the boundaries of this maturational potential are likely regulated by genetic predispositions, experiences and environmental perturbations mediate the individual development of cognitive and mental characteristics.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33135798591&p=1pl&v=1&x=ZwbntusB_X6GCKbtvuSHfg
10.1073/pnas.1603865113,Psychology_easy_437,We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception.,We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception.,"This slow motion intentionality bias occurred, in part, because slow motion video caused participants to feel like the actor had more time to act, even when they knew how much clock time had actually elapsed. Four additional experiments (n = 2,737) reveal that allowing viewers to see both regular speed and slow motion replay mitigates the bias, but does not eliminate it. We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception.","Four additional experiments (n = 2,737) reveal that allowing viewers to see both regular speed and slow motion replay mitigates the bias, but does not eliminate it. We conclude that an empirical understanding of the effect of slow motion on mental state attribution should inform the life-or-death decisions that are currently based on tacit assumptions about the objectivity of human perception. This slow motion intentionality bias occurred, in part, because slow motion video caused participants to feel like the actor had more time to act, even when they knew how much clock time had actually elapsed.",[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/showing-people-slow-motion-video-of-crime-found-to-distort-perceived-intent/
10.1177/0146167218781000,Psychology_easy_440,"""Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings,"" the researchers concluded.",Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings.,"Again, the findings in the Study b2 were consistent with the findings in Study b1. ""Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings,"" the researchers concluded. Conclusions

Overall, despite knowing that BS men can be undermining, women still prefer them over non-BS men, Gul and Kupfer wrote, adding that the connection exists because the desirable effects of benevolent sexism, for women, outweigh the potential downsides.","The interaction of pHS and willingness to invest was also non-significant meaning that the relationship between perceived willingness to invest and attractiveness was not affected by high versus low pHS. Findings from Study 3 supported the benevolence as a mate-preference hypothesis by ruling out the protection racket hypothesis as an alternative explanation for our findings. Specifically, women's perceived level of male HS did not predict the attractiveness of the BS romantic partner, and neither did it moderate the relationship between perceived willingness to invest and attractiveness.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34441972282&p=1pl&v=1&x=fmWLcMRDjewitRY1RDF0QQ
10.1001/jamapsychiatry.2015.0627,Psychology_easy_442,"""Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions.""","CONCLUSIONS AND RELEVANCE Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions.","That being said, the results of the study may not be generalizable to other populations. ""The heritability of tic disorders was estimated to be approximately 77 percent,"" the study concluded. ""Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions.""","There were no differences in familial risk or heritability between male and female patients. CONCLUSIONS AND RELEVANCE Tic disorders, including TS and CTDs, cluster in families primarily because of genetic factors and appear to be among the most heritable neuropsychiatric conditions. Second, families were primarily recruited from specialist clinics, potentially resulting in the inclusion of more severe and impaired cases.",[5],Psychology,train,5.0,news,http://www.medicaldaily.com/tic-disorders-including-tourette-syndrome-among-most-heritable-neuropsychiatric-338700
10.1073/pnas.1816076116,Psychology_easy_443,"On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training.","On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training.","Among groups whose average untreated attitudesawhereas still supportive of womenawere relatively less supportive of women than other groups, our diversity training successfully produced attitude change but not behavior change. On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training. This paper extends our knowledge about the pathways to attitude and behavior change in the context of bias reduction.","Among groups whose average untreated attitudes-whereas still supportive of women-were relatively less supportive of women than other groups, our diversity training successfully produced attitude change but not behavior change. On the other hand, our diversity training successfully generated some behavior change among groups whose average untreated attitudes were already strongly supportive of women before training. This paper extends our knowledge about the pathways to attitude and behavior change in the context of bias reduction.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=38894428644&p=1pl&v=1&x=8Sgi8CXAGknOZsZyz4Up-g
10.1038/s41398-017-0067-5,Psychology_easy_444,"""These findings suggest that patients with AVH have the ability to alter activity and connectivity in speech and language regions, and raise the possibility that rtfMRI-NF training could present a novel therapeutic intervention in SCZ,"" the researchers wrote in their study, which was published on Feb. 12.

c 2018 TECHTIMES.com All rights reserved.","These findings suggest that patients with AVH have the ability to alter activity and connectivity in speech and language regions, and raise the possibility that rtfMRI-NF training could present a novel therapeutic intervention in SCZ.","""We want them to immediately put this aid into effect to lessen them, or stop the voices completely,"" Orlov said. The researchers said that the technique used in the study offered a novel approach that can potentially help patients with schizophrenia. ""These findings suggest that patients with AVH have the ability to alter activity and connectivity in speech and language regions, and raise the possibility that rtfMRI-NF training could present a novel therapeutic intervention in SCZ,"" the researchers wrote in their study, which was published on Feb. 12.

c 2018 TECHTIMES.com All rights reserved.","Successful down-regulation of left STG activity can increase functional connectivity between speech motor and perception regions. These findings suggest that patients with AVH have the ability to alter activity and connectivity in speech and language regions, and raise the possibility that rtfMRI-NF training could present a novel therapeutic intervention in SCZ. In 0% of patients with AVH, traditional antipsychotic drugs have little or no effect .",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33271198575&p=1pl&v=1&x=wOhChZgRdIwzIgAxTDqetw
10.1177/0956797614527114,Psychology_easy_445,"According to the researchers, the findings ""support the notion that pleasant touch plays a vital role in human social interactions by demonstrating that the sensitivity to pleasant touch emerges early in human development.""",These findings support the notion that pleasant touch plays a vital role in human social interactions by demonstrating that the sensitivity to pleasant touch emerges early in human development.,"The researchers note that this link between caregiver and infant could be supported by both ""nurture"" and ""nature"" explanations:

""One possibility is that infants' sensitivity to pleasant touch stems from direct or vicarious experience of differing levels of social touch as a function of their caregiver's sensitivity to social touch,"" explains Fairhurst. According to the researchers, the findings ""support the notion that pleasant touch plays a vital role in human social interactions by demonstrating that the sensitivity to pleasant touch emerges early in human development."" They argue that the ability to perceive and sensitively response to pleasant touch is likely vital early in life because of the fundamental role that touch plays in affiliation, bonding, and synchrony between infants and caregivers.","In line with our predictions, the current results revealed that only when stroked at medium velocity, (a) infants' heart rate decelerated, which reflects increased parasympathetic activity and is indicative of a decrease in arousal, and (b) infants' behavioral engagement with the stroking object (brush) increased, which is indicative of an increased interest in the stroking object. These findings support the notion that pleasant touch plays a vital role in human social interactions by demonstrating that the sensitivity to pleasant touch emerges early in human development. Critically, infants' selective physiological (decrease in heart rate) and behavioral (increased engagement) responses to medium-velocity brushing are in line with the response profile of a special class of nerve fibers in human adults-the CLTM afferents (which show preferential activity in response to medium-velocity brushing; see .",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/04/140402105744.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1016/j.sleh.2017.09.004,Psychology_easy_446,"""Teens starting school at 8:30 a.m. or later were the only group with an average time in bed permitting eight hours of sleep, the minimum recommended by expert consensus,"" said lead author Orfeu Buxton, associate professor of biobehavioral health at Penn State.","Teens starting school at 8:30 AM or later are the only group with an average time in bed permitting 8 hours of sleep, the minimum recommended by expert consensus for health and well-being.","/ no comments

Medicine, Health Care Teens Get More Sleep When... ""Teens starting school at 8:30 a.m. or later were the only group with an average time in bed permitting eight hours of sleep, the minimum recommended by expert consensus,"" said lead author Orfeu Buxton, associate professor of biobehavioral health at Penn State. ""Later school start times were associated with later wake times in our large, diverse sample.""","Conclusion: Later school start times are associated with later wake times in our large, diverse sample. Teens starting school at 8:30 AM or later are the only group with an average time in bed permitting 8 hours of sleep, the minimum recommended by expert consensus for health and well-being. Data collected from the Youth Risk Behavior Survey in 205 showed that 73% of high school students reported less than 8 hours of sleep on school nights.",[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/teens-get-more-sleep-when-school-starts-later/
10.1186/s12888-018-1613-2,Psychology_easy_447,The thing that made me stop was wondering what the rabbits would do.,The thing that made me stop was wondering what the rabbits would do.,"I never got really bad, but I was suicidal at one time. The thing that made me stop was wondering what the rabbits would do. That was the first thing I thought of, and I thought, 'Oh, yeah, I can't leave because the rabbits need me.'","I never got really bad, but I was suicidal at one time. The thing that made me stop was wondering what the rabbits would do. That was the first thing I thought of and I thought, oh yeah, I can't leave because the rabbits need me.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33315706974&p=1pl&v=1&x=O9_o4n2dfMJNltoCf4-R5w
10.1098/rspb.2011.1373,Psychology_easy_448,"""When laughter is elicited, pain thresholds are significantly increased, whereas when subjects watched something that does not naturally elicit laughter, pain thresholds do not change,"" the authors of the paper wrote.","In both cases, the results confirmed that when laughter is elicited, pain thresholds are significantly increased, whereas when subjects watched something that does not naturally elicit laughter, pain thresholds do not change (and are often lower).","""Many of these same things also happen when you sleep right, eat right, and exercise,"" Berk said, which is why he categorizes laughter under traditional healthy lifestyle activities. ""When laughter is elicited, pain thresholds are significantly increased, whereas when subjects watched something that does not naturally elicit laughter, pain thresholds do not change,"" the authors of the paper wrote. Physical workout

Do not take this to mean that laughing can replace physical activity or help you lose weight.","There was a significant effect of condition (comedy versus drama: F 1,38 ¼ 3.86, p ¼ 0.022 onetailed), but no effect owing to status (actor versus audience: In both cases, the results confirmed that when laughter is elicited, pain thresholds are significantly increased, whereas when subjects watched something that does not naturally elicit laughter, pain thresholds do not change (and are often lower). These results can best be explained by the action of endorphins released by laughter.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=38283211439&p=1pl&v=1&x=KzoJVa4Z8COB6Rv13eZtYQ
10.1002/da.22208,Psychology_easy_449,"""These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap and does not add to burden of care,"" study researcher Tierney Lorenz, an Indiana University post-doctoral research fellow, said in a press release.","These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap, and does not add to burden of care.","The research, which was published on Dec. 10 in Depression and Anxiety, shows that moderately intense workouts may be able to help with one of the side effects that women who take antidepressants face: low sex drive. ""These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap and does not add to burden of care,"" study researcher Tierney Lorenz, an Indiana University post-doctoral research fellow, said in a press release. The researchers saw that regularly exercising improved orgasms in all women.","Future trials will be needed to examine effectiveness in a clinical setting (as opposed to a carefully controlled laboratory-based trial). The results of the present study suggest that exercise improves sexual function in women experiencing sexual arousal side effects of antidepressants, with modest evidence of a specific benefit in exercising immediately before sexual activity. These findings have important implications for public health, as exercise as a treatment for sexual side effects is accessible, cheap, and does not add to burden of care.",[5],Psychology,train,5.0,news,http://www.cbsnews.com/news/exercise-combat-low-sex-drive-in-women-antidepressants/
10.1016/j.psyneuen.2018.06.017,Psychology_easy_450,"As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mothers and their infants (51 controls and 36 cases) were assessed.","As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mother-infant dyads (51 controls and 36 cases) were assessed.","This study highlights the importance of pregnant mothers seeking treatment for clinical depression, as it could have long-term beneficial effects for children.' There are limitations to this research as the researchers had a small sample study, and the researchers would recommend replication in a larger sample. As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mothers and their infants (51 controls and 36 cases) were assessed.","Of the total sample, 41 (84%) had a past history of MDD. As expected in a longitudinal study of an inner city group of people, subject retention reduced over time, and at 1 year postnatal only 87 mother-infant dyads (51 controls and 36 cases) were assessed. However, there was no statistically significant difference at any time point between the proportion of cases and controls remaining in the study; furthermore, there were no statistically significant differences in socio-demographic information at baseline between those who did and did not complete the 1 year assessments, either for cases or for controls (data not shown).",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=34582615910&p=1pl&v=1&x=yNUgx8DtcIrUJDDfGjimRQ
10.1001/jamapsychiatry.2018.0296,Psychology_easy_451,"The multivariable population-attributable risk proportions were 14.2 and 4 percent for deployment within the first 12 months of service and DT of six months or less, respectively.",Multivariable population-attributable risk proportions were 14.2% for deployment within the first 12 months of service and 4.0% for DT of 6 months or less.,"There was no correlation for duration of first deployment with subsequent SA. The multivariable population-attributable risk proportions were 14.2 and 4 percent for deployment within the first 12 months of service and DT of six months or less, respectively. ""Time in service before first deployment and DT are modifiable risk factors for SA risk among soldiers,"" the authors write.",Analysis of 2-way interactions indicated that the associations of early deployment and DT with SA risk were not modified by other characteristics. Multivariable population-attributable risk proportions were 14.2% for deployment within the first 12 months of service and 4.0% for DT of 6 months or less. CONCLUSIONS AND RELEVANCE Time in service before first deployment and DT are modifiable risk factors for SA risk among soldiers.,[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33840292272&p=1pl&v=1&x=5i4dL45SbFkAfcSGluSIYQ
10.1016/j.ypmed.2014.08.023,Psychology_easy_453,"""These results appear to suggest that avoiding car driving may be beneficial to wellbeing,"" write the study's authors.","Together, these results appear to suggest that avoiding car driving may be beneficial to wellbeing.","The study also reports a similar finding for commuters who ditch their car for public transport. ""These results appear to suggest that avoiding car driving may be beneficial to wellbeing,"" write the study's authors. ""This view complements existing evidence of a negative association between driving and physical health and is consistent with the hypothesis that car driving (a non-passive travel mode that requires constant concentration) can give rise to boredom, social isolation and stress.""","Besides, only a small journey time mean and variance was observed amongst car drivers in the sample (mean = 22.9 min, withinindividual SD = 12.03). Together, these results appear to suggest that avoiding car driving may be beneficial to wellbeing. This view complements existing evidence of a negative association between driving and physical health , and is consistent with the hypothesis that car driving (a non-passive travel mode that requires constant concentration ) can give rise to boredom , social isolation and stress ONS, 2014; .",[5],Psychology,train,5.0,news,http://www.minnpost.com/second-opinion/2014/09/yes-ditching-car-your-commute-work-improves-well-being
10.1016/j.eurpsy.2018.06.006,Psychology_easy_454,The investigators recommend additional research to model the relationship between early adversity and genetic risk that contributes to social cognitive development.,This remains a priority for future research that seeks to model the relationship between early adversity and genetic risk in contribution to social cognitive development.,"Of these, 25 research articles were found to meet the study's strict criteria and were included in the review. The investigators recommend additional research to model the relationship between early adversity and genetic risk that contributes to social cognitive development. Understanding the mechanisms by which neurocognitive and biological factors come into play is also an important subject for future study.","). This remains a priority for future research that seeks to model the relationship between early adversity and genetic risk in contribution to social cognitive development. Furthermore, there is some evidence that this relationship may be conditional on genetic variation at the 5-HTT locus .",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=37084270100&p=1pl&v=1&x=HGYj6JYMATHn_xdTjPQWjg
10.1177/1948550617750737,Psychology_easy_455,"Maher and Igou conclude that ""to halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed.""","To halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed.","This was true for both liberals and conservatives. Maher and Igou conclude that ""to halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed."" That won't be easy: It'll require reversing the prejudice-reinforcing media habits we've acquired in the cable news and Internet eras, and opening ourselves to a range of ideas.","Our research provides evidence of disillusionment-induced political polarization, using naturalistic quasi-experimental and experimental designs. These intriguing findings advance insights into the effects of disillusionment and the important practical implications of this experience. To halt the slide into cumulative polarization, the underlying causes of mass disillusionment should be addressed.",[5],Psychology,train,5.0,news,https://psmag.com/news/emotional-roots-of-political-polarization
10.1093/alcalc/agv096,Psychology_easy_456,"""It is possible that alcohol may only affect perception of attractiveness at a higher level of alcohol consumptions, which was not observable with the naturalistic design used here,"" write the researchers.","It is possible that alcohol may only affect perception of attractiveness at a higher level of alcohol consumption, which was not observable with the naturalistic design used here.","People in the laboratory experiments tended to consume more alcohol than those in the pubs. ""It is possible that alcohol may only affect perception of attractiveness at a higher level of alcohol consumptions, which was not observable with the naturalistic design used here,"" write the researchers. Limitations and implications

This study has several important limitations.","This mean BrAC arguably reflects a lower level of alcohol intoxication than in laboratory experiments where participants are administered 0.4 g/kg of alcohol . It is possible that alcohol may only affect perception of attractiveness at a higher level of alcohol consumption, which was not observable with the naturalistic design used here. We observed no evidence for the closing-time effect in our exploratory analyses.",[5],Psychology,train,5.0,news,http://www.minnpost.com/second-opinion/2015/08/beer-goggles-effect-myth-study-suggests
10.1007/s11031-015-9507-9,Psychology_easy_457,"""After the initial deterioration of mood following crying that is usually observed in laboratory studies, it takes some time for the mood, not just to recover, but also to increase above the levels that it had before the emotional event, a pattern of findings which corresponds to the results of retrospective studies,"" the lead author says, per the Telegraph.","After the initial deterioration of mood following crying that was observed in laboratory studies, it apparently takes some time for the mood, not just to recover, but also to become even less negative than before the emotional event, which corresponds to the results of retrospective studies.","This latest study may offer an explanation. ""After the initial deterioration of mood following crying that is usually observed in laboratory studies, it takes some time for the mood, not just to recover, but also to increase above the levels that it had before the emotional event, a pattern of findings which corresponds to the results of retrospective studies,"" the lead author says, per the Telegraph. (Some people feel the urge to cry in this strange locale.)","The observed relation between crying and more long-term mood recovery reconciles seemingly contrasting earlier results and provides a simple and obvious explanation. After the initial deterioration of mood following crying that was observed in laboratory studies, it apparently takes some time for the mood, not just to recover, but also to become even less negative than before the emotional event, which corresponds to the results of retrospective studies. Theories on the functions of crying can be classified into two global categories ( ).",[5],Psychology,train,5.0,news,http://www.newser.com/story/211829/yes-there-is-such-a-thing-as-a-good-cry.html
10.1016/j.schres.2013.11.014,Psychology_easy_458,"The new study is the first family study that, according to the researchers, ""examines both non-psychotic cannabis users and non-cannabis user controls as two additional independent samples, enabling the examination of whether the risk for schizophrenia is increased in family members of cannabis users who develop schizophrenia compared with cannabis users who do not and also whether that morbid risk is similar or different from that in family members of schizophrenia patients who never used cannabis.""","The present study, to our knowledge, is the first family study that examines both nonpsychotic cannabis users and non-cannabis user controls as two additional independent samples, enabling the examination of whether the risk for schizophrenia is increased in family members of cannabis users who develop schizophrenia compared with cannabis users who do not and also whether that morbid risk is similar or different from that in family members of schizophrenia patients who never used cannabis.","""The results of the current study suggest that having an increased familial morbid risk for schizophrenia may be the underlying basis for schizophrenia in cannabis users and not cannabis use by itself,"" note the researchers. The new study is the first family study that, according to the researchers, ""examines both non-psychotic cannabis users and non-cannabis user controls as two additional independent samples, enabling the examination of whether the risk for schizophrenia is increased in family members of cannabis users who develop schizophrenia compared with cannabis users who do not and also whether that morbid risk is similar or different from that in family members of schizophrenia patients who never used cannabis."" This resulted in information on 1,168 first-degree relatives and a total of 4,291 relatives.","However, it only had an association with earlier age of onset and not development of illness per se. The present study, to our knowledge, is the first family study that examines both nonpsychotic cannabis users and non-cannabis user controls as two additional independent samples, enabling the examination of whether the risk for schizophrenia is increased in family members of cannabis users who develop schizophrenia compared with cannabis users who do not and also whether that morbid risk is similar or different from that in family members of schizophrenia patients who never used cannabis. For the purposes of this study, we have not explored any other possible risk factors that could be contributing to modified brain development during adolescence and acknowledge that others may be significant as well.",[5],Psychology,train,5.0,news,http://psychcentral.com/news/2013/12/10/harvard-marijuana-doesnt-cause-schizophrenia/63148.html
10.1016/j.evolhumbehav.2014.08.003,Psychology_easy_459,"""To our knowledge,"" the researchers said, ""this is the first demonstration of an extraneous color effect in non-human primates.""","To our knowledge, this is the first demonstration of an extraneous color effect in non-human primates.","The researchers found a significant female bias toward the images of male hindquarters, but only when a red frame surrounded the image. ""To our knowledge,"" the researchers said, ""this is the first demonstration of an extraneous color effect in non-human primates."" Female monkeys did not show a preference for other female hindquarter, regardless of the color of the surrounding frame.","The greater lookingtime by females for the male scrotum on a red background suggests that females saw this stimulus as more interesting compared to other stimuli , and the absence of an effect for looking duration in males suggests they did not find this stimulus more interesting. To our knowledge, this is the first demonstration of an extraneous color effect in non-human primates. Extraneous red increased females' interest in viewing a male scrotum while extraneous blue did not.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141017101222.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1098/rspb.2019.0898,Psychology_easy_460,"Interestingly, male spongers spent significantly more time foraging and less time resting than non-spongers.","Male spongers spent significantly more time foraging, and less time resting and travelling, than did male non-spongers.","After analysing their data, the team came to the conclusion that that those males who used sponges for foraging associated significantly more often with other ""spongers,"" regardless of how related they were to their companions. Interestingly, male spongers spent significantly more time foraging and less time resting than non-spongers. ""This study suggests that, like their female counterparts and indeed like humans, male dolphins form social bonds based on shared interests.""","Here, we show that male spongers associated significantly more often with other male spongers irrespective of their level of relatedness. Male spongers spent significantly more time foraging, and less time resting and travelling, than did male non-spongers. Interestingly, we found no difference in time spent socializing.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=39452289042&p=1pl&v=1&x=aA36XjWUZO59sYu46VnOdw
10.1016/j.psyneuen.2014.05.012,Psychology_easy_461,"""These findings support the idea that the tendency to describe and accept distressing experiences may buffer the impact of psychological distress on physiological arousal,"" the researchers write in the journal Psychoneuroendochronology.",Conclusion-These findings support the idea that the tendency to describe and accept distressing experiences may buffer the impact of psychological distress on physiological arousal.,"People who are willing to live with unwanted outcomes refrain from doing physical damage to themselves. ""These findings support the idea that the tendency to describe and accept distressing experiences may buffer the impact of psychological distress on physiological arousal,"" the researchers write in the journal Psychoneuroendochronology. ""Anxiety, negative affect, and rumination were positively related to the cortisol awakening response at lower levels of dispositional mindfulness, but not at higher levels,"" the researchers report.","Collectively, these results provide convergent evidence that dispositional mindfulness, particularly the acceptance component, moderates the association between psychological distress and the CAR. Conclusion-These findings support the idea that the tendency to describe and accept distressing experiences may buffer the impact of psychological distress on physiological arousal. These metacognitive processes may be important moderators in unraveling the complex relationship between psychological distress and physiological stress reactivity.",[5],Psychology,train,5.0,news,http://www.psmag.com/kickers/findings-kickers/mindfulness-can-avert-bodily-responses-emotional-stress-83245/
10.1073/pnas.1612233114,Psychology_easy_462,"""Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted.""","Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted.","The complexity of human bonding cannot be fully captured in nonhuman animal models, particularly in pathological bonding, such as that in autistic spectrum disorder or postpartum depression."" ""Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted."" _____

Shir Atzil et al.","Together, these data indicate that dopamine is involved in human bonding. Thus, investigations of the neurochemistry of social bonding in humans, for which this study provides initial evidence, are warranted. Mothers who were sensitive to their infants' cues for social engagement and who adjusted their own behavior to meet those needs (referred to as ""mother-infant synchrony""), showed greater activations in the left NAcc and lower activation in the right amygdala when viewing films of their infants than did nonsynchronous mothers (4).",[5],Psychology,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/nvsr9_uN5tw/dopamine-human-bonding-04634.html
10.1002/ejp.927,Psychology_easy_463,"""The findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception,"" the scientists concluded.",Conclusion: These findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception.,"""The reduction in pain experienced by our participants was significant, with pain intensity reducing by an average of 37% when the video feed seen by the participants was live, compared to recorded,"" explained co-author James Pamment, a psychologist at Anglia Ruskin University. ""This reduction arguably constitutes a clinically useful analgesic effect."" ""The findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception,"" the scientists concluded.","Results: We found that full body illusions were experienced by patients with chronic pain and further, that pain intensity was reduced by an average of 37% after illusion (synchronous) conditions. Conclusion: These findings add support to theories that high-level multisensory body representations can interact with homeostatic regulation and pain perception. Significance: Pain intensity in chronic pain patients was reduced by 37% by 'out of body' illusions.",[5],Psychology,train,5.0,news,http://feedproxy.google.com/~r/BreakingScienceNews/~3/8LVE4HIbZio/out-of-body-experience-chronic-pain-04094.html
10.1001/jamapsychiatry.2015.10,Psychology_easy_464,"This study adds to the small, emerging body of research on the correlates of MDD among African Americans,"" the study concludes.","This study adds to the small, emerging body of research 15,16,64,65 on the correlates of MDD among African Americans.","However, rural non-Hispanic white women had higher rates of 12-month MDD (10.3 percent) and mood disorder (10.3 percent) than their urban counterparts (3.7 percent and 3.8 percent, respectively). ""These findings offer an important first step toward understanding the cumulative effect of rural residence and race/ethnicity on MDD among African-American women and non-Hispanic white women and suggest the need for further research in this area. This study adds to the small, emerging body of research on the correlates of MDD among African Americans,"" the study concludes.","Our results suggest that while rural residence is associated with lower prevalences of MDD and mood disorder among African American women, it is a risk factor for non-Hispanic white women. These findings offer an important first step toward understanding the cumulative effect of rural residence and race/ethnicity on MDD among African American women and non-Hispanic white women and suggest the need for further research in this area. This study adds to the small, emerging body of research 15,16,64,65 on the correlates of MDD among African Americans.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2015/04/150408113615.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_society+%28Top+Society+News+--+ScienceDaily%29
10.1073/pnas.1311041111,Psychology_easy_465,"Their results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness.","Our results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness.","The researchers found improvement after sight onset in contrast sensitivity tests, which measure basic visual function and have well-understood neural underpinnings. Their results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness. Our results show remarkable plasticity and vision continues to improve in many children long after the surgery,"" said Senior Author Peter J. Bex, Ph.D., Senior Scientist, Schepens Eye Research Institute/Mass.","Surprisingly, we find substantial improvement after sight onset in contrast sensitivity, a basic visual function that has well-understood neural underpinnings. Our results show that the human visual system can retain plasticity beyond critical periods, even after early and extended blindness. Access to this population allowed us to examine contrast sensitivity across a large sample of sight restoration patients compared with previous reports .",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/01/140127112800.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1177/0956797614568318,Psychology_easy_466,"""Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years,"" McAdams and Guo explain.","Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years.","And this redemption narrative was also stronger for adults who showed greater overall mental health and well-being. ""Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years,"" McAdams and Guo explain. But there were also some unexpected findings:

""We were surprised to find that African American adults in our sample actually had higher levels of generativity and more pronounced redemptive life stories compared to the white participants,"" says McAdams.","The same kind of life story is also associated with increased levels of public-service motivation and psychological well-being but is unrelated to depression. Thus, the prototype of the redemptive self appears to be a life-story format that is deeply implicated in healthy psychosocial adaptation in the midlife years. Finally, two well-validated narrative constructs that are not part of the redemptive-self pattern-contamination sequences and meaning making-appeared to be unrelated to levels of psychosocial adaptation at midlife, with the exception of a modest association between contamination sequences and depression.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2015/03/150309124152.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1126/science.aam8138,Psychology_easy_467,"Their performance parallels that seen in apes and suggests that planning evolved independently in corvids, which opens new avenues for the study of cognitive evolution,a the authors wrote.","Their performance parallels that seen in apes and suggests that planning evolved independently in corvids, which opens new avenues for the study of cognitive evolution.","The research shows that aravens plan for events unrelated to caching a tool-use and bartering a with delays of up to 17 hours, exert self-control, and consider temporal distance to future events. Their performance parallels that seen in apes and suggests that planning evolved independently in corvids, which opens new avenues for the study of cognitive evolution,a the authors wrote. ---

Image credit: Unsplash/Tyler Quiring

Comments

comments","Here, we show that ravens plan for events unrelated to caching-tool-use and bartering-with delays of up to 17 hours, exert self-control, and consider temporal distance to future events. Their performance parallels that seen in apes and suggests that planning evolved independently in corvids, which opens new avenues for the study of cognitive evolution. The cognitive skill set that allows for planning outside the current sensory context operates across a range of domains, from planning a dinner party to making retirement plans.",[5],Psychology,train,5.0,news,http://www.redorbit.com/news/science/1113418415/ravens-show-surprising-ability-to-plan-ahead/
10.1016/j.visres.2009.11.003,Psychology_easy_468,"""A woman who has large lips, suggesting a strong mating potential, with average length and width ratios will always be more attractive than a woman with narrow lips and average length and width ratios,"" wrote the researchers.","A woman who has large lips, suggesting a strong mating potential, with average length and width ratios will always be more attractive than a woman with narrow lips and average length and width ratios.","""Much like how studies show that the higher your hip-to-waist ratio in some African tribal cultures, the more attractive you are, full lips can also make you seem more attractive."" ""A woman who has large lips, suggesting a strong mating potential, with average length and width ratios will always be more attractive than a woman with narrow lips and average length and width ratios,"" wrote the researchers. They found that people were rated as most attractive when the vertical distance between the eyes and mouth was about 36 percent of its length, and the horizontal distance between the eyes was about 46 percent of the face's width (you can see examples of different distances of facial features in the image above).","It should be noted that the optimal spatial relations found in the present study can also co-exist with preferences for sexually dimorphic features. A woman who has large lips, suggesting a strong mating potential, with average length and width ratios will always be more attractive than a woman with narrow lips and average length and width ratios. In other words, a woman with large lips and unattractive length and width ratios may or may not be preferred to a woman with narrow lips and ideal length and width ratios.",[5],Psychology,train,5.0,news,http://www.womenshealthmag.com/beauty/the-obsession-with-big-lips
10.1073/pnas.1508932113,Psychology_easy_469,"""These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success,"" the authors wrote.","These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success.","The latter profile was almost twice as likely to be successful, they concluded. ""These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success,"" the authors wrote. ""Our research suggests that a nonverbal dominance display increases a person's chances of being selected as a potential mate.","Specifically, perceivers' impressions of a target's dominance increase significantly as the target assumes a more expanded and open nonverbal posture . These findings indicate that in modern-day dating contexts, in which initial attraction often is determined by a rapid decision following a brief interaction or seeing a photograph, displays of expansive posture increase one's chances of initial romantic success. * Given its link to resource acquisition, possession, and allocation control/sharing, the functional preference for dominance in mates may have emerged because it is linked to one's own longer life span as well as to reproductive success and offspring survival.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33604666086&p=1pl&v=1&x=9OGLXByWkLjibLg8g-ty1w
10.1073/pnas.1421285111,Psychology_easy_470,"""Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats,"" wrote the authors in their study.","Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats.","Given these results, the researchers speculate that, in general, an aging brain may compensate for memory loss by increasing clustering and riluzole appears to promote this process. ""Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats,"" wrote the authors in their study. Considering riluzole is already FDA-approved, this drug might soon be repurposed to treat memory loss in humans if further studies substantiate the results.","Although neuron death is minimal in the absence of AD, age-related cognitive decline does occur in animals as well as humans, and it decreases quality of life for elderly people. Here, we show that riluzole can protect against some of the synaptic alterations in hippocampus that are linked to age-related memory loss in rats. Treated aged rats were protected against age-related cognitive decline displayed in nontreated aged animals.",[5],Psychology,train,5.0,news,http://www.medicaldaily.com/riluzole-drug-prescribed-als-prevents-and-treats-memory-loss-aging-brains-315484
10.1093/her/cyt156,Psychology_easy_471,"""Understanding how to motivate sexual risk reduction behaviors is a key step towards improving health outcomes among adolescents,"" they write.",Understanding how to motivate sexual risk reduction behaviors is a key step towards improving health outcomes among adolescents.,"""The techniques that work to promote healthy behavior in adults may not be the same as those that work best for adolescents."" The authors recommend that future research should determine how adolescents' perceived risk of initiating behavior affects their actual behavior. ""Understanding how to motivate sexual risk reduction behaviors is a key step towards improving health outcomes among adolescents,"" they write.","Future studies should focus on the effect of both gain-and loss-framed messages on prevention itself-that is delaying the initiation of risk behaviors. Furthermore, future research should determine how adolescents' perceived risk of initiating a particular behavior affects their responsiveness to different message frames. Understanding how to motivate sexual risk reduction behaviors is a key step towards improving health outcomes among adolescents.",[5],Psychology,train,5.0,news,http://www.healthcanal.com/sexual-health/47028-helping-adolescents-understand-the-consequences-of-risky-sexual-behavior.html
10.1177/0956797614533968,Psychology_easy_473,Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences.,Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences.,"In addition, when fathers enacted or espoused a more egalitarian distribution of household labor, their daughters in particular expressed a greater interest in working outside the home and having a less stereotypical occupation. Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences. The researchers note that this could be caused by other things, too--like the fact that those men might be married to women who work outside the home or have more progressive views on gender roles.","In addition, when fathers enacted or espoused a more egalitarian distribution of household labor, their daughters in particular expressed a greater interest in working outside the home and having a less stereotypical occupation. Fathers' implicit gender-role associations also uniquely predicted daughters' (but not sons') occupational preferences. These findings suggest that a more balanced division of household labor between parents might promote greater workforce equality in future generations.",[5],Psychology,train,5.0,news,http://lifehacker.com/dads-who-help-out-around-the-home-might-raise-more-ambi-1598007639
10.1111/nyas.12348,Psychology_easy_474,Reported dropout rates were low and compliance rates high.,Reported dropout rates were low and compliance rates high.,Zanesco said further research is needed before meditation can be identified as way to counter the effects of aging on the brain. He also said that participants' lifestyle or personality might have contributed to the results. Reported dropout rates were low and compliance rates high.,"Twelve studies were included in the review, six of which were randomized controlled trials. Reported dropout rates were low and compliance rates high. We conclude that meditation interventions for older adults are feasible, and preliminary evidence suggests that meditation can offset age-related cognitive decline.",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=33671356306&p=1pl&v=1&x=YlM1kKttuvjDc1n0ueAWpw
10.1152/jn.00822.2014,Psychology_easy_475,"""Our study establishes an essential and modality-specific requirement for HH signaling in maintaining neurophysiological taste sensation in mice, underlying the likely cause of taste disruption in HPI-treated patients,"" the authors wrote.","In summary, our study establishes an essential and modalityspecific requirement for HH signaling in maintaining neurophysiological taste sensation in mice, underlying the likely cause of taste disruption in HPI-treated patients.","While these changes affected taste responses from the chorda tympani nerve, they surprisingly did not affect tactile or temperature sensation. ""Our study establishes an essential and modality-specific requirement for HH signaling in maintaining neurophysiological taste sensation in mice, underlying the likely cause of taste disruption in HPI-treated patients,"" the authors wrote. ""We propose that taste disturbances in HPI-treated patients derive from HH-dependent loss of taste papilla integrity and taste buds, with a specific, concomitant reduction of peripheral nerve taste responses that transmit taste sensation centrally.""","Overall, the data clearly indicate that HPI treatment differentially affects oral sensations and demonstrate the importance of updated, accurate maps of taste, touch and thermal receptors in fungiform papillae. In summary, our study establishes an essential and modalityspecific requirement for HH signaling in maintaining neurophysiological taste sensation in mice, underlying the likely cause of taste disruption in HPI-treated patients. We propose that taste disturbances in HPI-treated patients derive from HH-dependent loss of taste papilla integrity and taste buds, with a specific, concomitant reduction of peripheral nerve taste responses that transmit taste sensation centrally.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2015/03/150302121622.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1080/02646830601117142,Psychology_easy_476,"Although some partners were not able to find an explanation for their symptoms, some perceived that they were related in some way to the altered physiology of their female partners during pregnancy.",Some participants were unable to find explanations for symptoms but some perceived that they were related in some way to the altered physiology of their female partners during pregnancy.,"The couple even began to have the same cravings, like Chinese takeout, orange Lucozade, and salt-and-vinegar chips, which they both normally dislike. Although some partners were not able to find an explanation for their symptoms, some perceived that they were related in some way to the altered physiology of their female partners during pregnancy. This belief would apply to Ashby's case, since Allsopp had a previous miscarriage, The Independent reported.","Although the former were reported to their GPs, no definitive diagnosis was made despite medical investigations being performed. Some participants were unable to find explanations for symptoms but some perceived that they were related in some way to the altered physiology of their female partners during pregnancy. These findings highlight the need for further research to acquire deeper insight into men's experiences of, and responses to, pregnancy as a way of explaining the syndrome.",[5],Psychology,train,5.0,news,http://www.medicaldaily.com/dad-be-gets-sympathy-morning-sickness-leave-work-couvade-syndrome-real-thing-302816
10.1177/0956797613512129,Psychology_easy_477,"In sum:

While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism.","While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism.","Essentially, the researchers assert that cyclical thinking encourages people to start saving immediately, no matter the circumstances, whereas linear thinking allows for ongoing delays in putting something aside, however meager. In sum:

While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism. Practically, people can make savings decisions at any time, and we surmise that deferral under the linear savings method may continue unabated as the person's distant future becomes the near future and eventually the present.","In contrast, the linear savings method encourages deferral of the savings task to the future, inflating savings predictions in the distant future, but dampening current saving. While most people may not think about how much they will save during specific future periods, this study demonstrated the distinction between saving now and saving in the future and the fact that these two decisions are unique and affected by implementation planning and future optimism. Practically, people can make savings decisions at any time, and we surmise that deferral under the linear savings method may continue unabated as the person's distant future becomes the near future and eventually the present.",[5],Psychology,train,5.0,news,http://www.psmag.com/navigation/business-economics/cyclical-thinking-might-help-save-money-72161/
10.1001/jamapsychiatry.2014.1582,Psychology_easy_478,SZ and BP differ clinically but they share many features.,"Although SZ and BP often differ clinically, they share many features.","SZ and BP differ clinically but they share many features. Average spine density was reduced in individuals with BP (by 10.5 percent) and in individuals with SZ (by 6.5 percent) compared with control patients, although the reduction in individuals with SZ just missed significance. There was a significant reduction in the average number of spines per dendrite in both individuals with SZ (72.8 spines per dendrite) and individuals with BP (68.9 spines per dendrite) compared with control group individuals (92.8 spines per dendrite).","3 The DLPFC plays a key role in working memory, 5 which is commonly impaired in SZ. Although SZ and BP often differ clinically, they share many features. 17 Therefore, spine loss might be observed in the DLPFCs from individuals with BP.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/10/141002092428.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1007/s00213-013-3269-4,Psychology_easy_479,"""Unfortunately, the subtle change in the effects of alcohol on performance over time may lead older adults to ignore these risks as they are unlikely to have experienced significant consequences or impairment resulting from this level of consumption at earlier points in their lives,"" write the study's authors.","Unfortunately, the subtle change in the effects of alcohol on performance over time may lead older adults to ignore these risks as they are unlikely to have experienced significant consequences or impairment resulting from this level of consumption at earlier points in their lives.","This new study suggests that the consumption of alcohol, even at low levels, exacerbates that negative effect. ""Unfortunately, the subtle change in the effects of alcohol on performance over time may lead older adults to ignore these risks as they are unlikely to have experienced significant consequences or impairment resulting from this level of consumption at earlier points in their lives,"" write the study's authors. Changing demographics make this finding particularly worrisome.","By highlighting potential risks associated with individual episodes of moderate consumption, these findings add an important perspective to the literature documenting the health benefits in older adults associated with a moderate drinking lifestyle ). Unfortunately, the subtle change in the effects of alcohol on performance over time may lead older adults to ignore these risks as they are unlikely to have experienced significant consequences or impairment resulting from this level of consumption at earlier points in their lives. Due to the understudied nature of this question and its potential impact on a growing percentage of the population, further investigation is needed.",[5],Psychology,train,5.0,news,http://www.minnpost.com/second-opinion/2014/03/single-drink-can-impair-drivers-aged-50-and-older-study-finds
10.1093/geronb/gbt118,Psychology_easy_480,"According to the study's abstract, people who are more than 65 years of age are almost one point on a 0--6 scale less tired than people aged between 15 and 24.",People who are more than 65 years of age are almost one point on a 0-6 scale less tired than people aged between 15 and 24.,"As opposed to previous theories, tiredness decreased as respondents got older. According to the study's abstract, people who are more than 65 years of age are almost one point on a 0--6 scale less tired than people aged between 15 and 24. The findings are indeed fascinating, but Kudrna is careful not to allow any easy inferences.","Contrary to much previous research, tiredness decreases with age. People who are more than 65 years of age are almost one point on a 0-6 scale less tired than people aged between 15 and 24. Clinical implications and methodological limitations are discussed.",[5],Psychology,train,5.0,news,http://www.thedailybeast.com/articles/2013/12/13/can-your-grandpa-kick-your-ass.html
10.1038/s41598-018-24528-3,Psychology_easy_482,"""Our findings are relevant for behavioral economists, psychologists and artists alike, as they demonstrate that 'deliberative and effortful thinking' can play a crucial role in overcoming cognitive heuristics related to socially constructed concepts and stereotype,"" they wrote in the paper.","Accordingly, our findings are relevant for behavioral economists, psychologists and artists alike, as they demonstrate that 'deliberative and effortful thinking' can play a crucial role in overcoming cognitive heuristics related to socially constructed concepts and stereotypes.","""These data demonstrate how critical factors outside the notes themselves, like the information you have about a performer (explicitly in the form of a prime or implicitly in the form of positioning on stage at Carnegie Hall or on a subway platform) can transform what you are able to hear and how you evaluate a musical performance."" These findings have implications beyond music preference, the researcher explained. ""Our findings are relevant for behavioral economists, psychologists and artists alike, as they demonstrate that 'deliberative and effortful thinking' can play a crucial role in overcoming cognitive heuristics related to socially constructed concepts and stereotype,"" they wrote in the paper.","Our study provides new insight into the neural circuitry underlying a phenomenon that has long been articulated by philosophers and demonstrated in behavioral studies: the activation of a cultural category-such as a professional or student performer-can affect the perception and valuation of a stimulus, even over a relatively long duration. We extend those findings with initial evidence suggesting that deliberative thinking can mitigate the behavioral bias that arises from affective responses. Accordingly, our findings are relevant for behavioral economists, psychologists and artists alike, as they demonstrate that 'deliberative and effortful thinking' can play a crucial role in overcoming cognitive heuristics related to socially constructed concepts and stereotypes.",[5],Psychology,train,5.0,news,http://healthmedicinet.com/news/overcoming-bias-about-music-takes-work/
10.1080/14649365.2013.862846,Psychology_easy_483,"But the eradication of fear requires wider social responsibility for violence.""",But the eradication of fear requires wider social responsibility for violence.,"""The actions described in this paper are only necessary in a wider social and political climate which continues to place more emphasis on individual than collective responsibility for domestic violence,"" Pain concludes. But the eradication of fear requires wider social responsibility for violence."" In other words, we all have a part to play in creating a safer society, through resisting abuse, reporting abuse, and supporting the abused and their rights through our political, judicial and legal systems.","Fear is never simply about one's immediate situation, then, but is relational; emotions felt in an intimate setting may be reinforced or alleviated by actions at other scales. But the eradication of fear requires wider social responsibility for violence. Cheryl: I feel more confident now...about life as well…I'm proud of myself like how far I've came and like that I done it on my own.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/03/140314093650.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1111/risa.12369,Psychology_easy_484,"The authors state that ""developing and imparting more gist-based knowledge, to engage more intuitive thinking about online risk taking, may well help to protect young people against some of the dangers involved in certain online activities.""","Developing and imparting more gist based knowledge, in order to engage more intuitive thinking about online risk-taking, may well help to protect young people against some of the dangers involved in certain online activities.","Adolescents who used verbatim reasoning were found to have higher online risk intentions. The authors suggest that the differences in reasoning about risks could be important factors to consider when designing online training and education for both preventative and protective measures. The authors state that ""developing and imparting more gist-based knowledge, to engage more intuitive thinking about online risk taking, may well help to protect young people against some of the dangers involved in certain online activities.""","Certainly, since risk prevention messages have been shown to be effectively communicated via social networking sites communication of risk in an online environment about online risk is an area warranting further investigation. Developing and imparting more gist based knowledge, in order to engage more intuitive thinking about online risk-taking, may well help to protect young people against some of the dangers involved in certain online activities. Further research on young people's online risk taking will not only help identify the decision making processes involved when making risky decisions about online activities, but also help develop more effective education strategies that can encourage young people to reap the benefits of the virtual world while also protecting them against potential threat.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2015/03/150330095114.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29
10.1098/rspb.2015.1292,Psychology_easy_485,"""To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks,"" wrote the authors.","To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks.","That said, when participants were given 30 seconds with the photo pairs, the differences in recognition ability between the three groups became most obvious. ""To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks,"" wrote the authors. Importantly, they added that the trained examiners identified faces using analytical methods, ""processes that differ qualitatively from those supporting memory for individual faces,"" they wrote.","Although examiners' performance was not statistically superior to controls in all experiments, it was always statistically superior to the student performance. To the best of our knowledge, this is the first convincing demonstration of a professional group showing higher accuracy on face matching tasks. Closer analysis also revealed two qualitative differences between examiners and non-expert groups.",[5],Psychology,train,5.0,news,http://www.medicaldaily.com/fbi-agents-forensic-experts-outperform-computer-algorithms-facial-recognition-tests-350814
10.5665/sleep.3412,Psychology_easy_486,Results suggest that sleep durations outside the normal range increase the genetic risk for depressive symptoms.,Therefore sleep durations outside the normal range increased the genetic risk for depressive symptoms.,"A study of 1,788 adult twins is the first to demonstrate a gene by environment interaction between self-reported habitual sleep duration and depressive symptoms. Results suggest that sleep durations outside the normal range increase the genetic risk for depressive symptoms. Among twins with a normal sleep duration of seven to 8.9 hours per night, the total heritability of depressive symptoms was 27 percent.","However, among individuals with short or long sleep duration we observed increased genetic infl uence on depressive symptoms, particularly at sleep duration extremes (5 h/night: h 2 = 53% [95% CI 31% to 75%]; 10 h/night: h 2 = 49% [95% CI 26% to 72%]). Therefore sleep durations outside the normal range increased the genetic risk for depressive symptoms. Notably, the pattern of results was unchanged: there was a signifi cant interaction between the genetic cross-path and sleep duration (a' c = 0.13, SE = 0.5, P = 0.01), resulting in U-shaped curve, with stronger genetic effects at both short and long sleep durations.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/01/140131230851.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.3109/17483107.2014.981874,Psychology_easy_487,"Dr Tsekleves said: ""The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist.""",The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist .,"One stroke survivor was even able to lift and drain a cooking pan for the first time since her stroke 11 years before and her hand ""wanted to open of its own accord."" Dr Tsekleves said: ""The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist."" One said: ""I can now play games and do things not possible for me before,"" while another said: ""It's great!","A perceived lack of support from physiotherapists was the most frequently mentioned factor associated with lack of compliance. The innovative use of the Nintendo Wii could present a way to enhance community based stroke rehabilitation of the arm by providing a motivating and cost-effective way of exercising that could be remotely monitored and exercises adjusted as required by a physiotherapist . Firstly, a comprehensive review of the literature is presented to foreground the development work that is the focus of this paper.",[5],Psychology,train,5.0,news,http://www.sciencedaily.com/releases/2014/12/141205093826.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news%2Ftop_technology+%28ScienceDaily%3A+Top+Technology+News%29
10.1007/s10071-015-0889-6,Psychology_easy_488,"""We suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes,"" Perlman and colleagues wrote in their study.","Based on these and other findings, we suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes.","Scientists said that the behavior shown by Koko was surprising since it is generally believed that apes cannot control their vocalizations or breathing. ""We suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes,"" Perlman and colleagues wrote in their study. The behavior exhibited by Koko may be impressive but it is unlikely that Koko and other gorillas would learn to ""speak"" to each other though the researchers said that this may possibly happen in a very distant evolutionary future.","Our analysis shows that Koko exercises voluntary control over the performance of nine distinctive VBBs, which involve variable coordination of her breathing, larynx, and supralaryngeal articulators like the tongue and lips. Based on these and other findings, we suggest that vocal learning and the ability to exercise volitional control over vocalization, particularly in a multimodal context, might have figured relatively early into the evolution of language, with some rudimentary capacity in place at the time of our last common ancestor with great apes. For example, Goodall, generalizing from her observations of free-ranging chimpanzees in the Gombe Reserve, came to the conclusion that ''the production of sound in the absence of the appropriate emotional state seems to be an almost impossible task for a chimpanzee' ' (1986: 125) .",[5],Psychology,train,5.0,news,http://www.techtimes.com/articles/77023/20150817/gorillas-show-early-signs-of-learning-to-talk-study.htm
10.1509/jmr.13.0499,Psychology_easy_489,The marketplace essentially offers more products that engage us in well-defined problem-solving.,The marketplace essentially offers more products that engage us in well-defined-problem solving.,"Advertisement

Psychology Today explains that these findings, according to the researchers, go beyond using LEGO creatively or not:

""Rather than using a map along with trial-and-error to find our next destination, we can now ask Siri to guide us seamlessly to that location; instead of following an Italian recipe, we can now saute a Bertolli ready-to-cook frozen meal for dinner, and instead of struggling to retrieve an answer to a question from our memory, we can instantaneously Google the information. The marketplace essentially offers more products that engage us in well-defined problem-solving. If you take these experiments at face value, the ""better understanding"" of this research is that the more we are confronted by and complete well-defined problems like LEGO kits or word finds or color-in-the-lines pictures, the less we choose to engage in and the worse we are at solving ill-defined problems: create something beautiful, discover something meaningful, find someone to love.","Furthermore, the results show that the effect of this mindset on consumers' choice is rather robust-it occurs even when we control for the effect of a chronic individual-difference factor (self-perceived creativity) and endures after a delay (i.e., as demonstrated by the order manipulation). The marketplace essentially offers more products that engage us in well-defined-problem solving. By considering the effects of a well-defined-problemsolving mindset on both goal striving and goal setting, our studies suggest that the consequences of such a mindset could be significant.",[5],Psychology,train,5.0,news,http://lifehacker.com/how-a-lego-kit-mentality-could-hurt-your-creativity-1712005926
10.1001/jamapsychiatry.2017.3998,Psychology_easy_490,"""Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women,"" the authors write.",CONCLUSIONS Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women.,"The researchers found that, compared with women receiving TE+IMP, those assigned to placebo were more likely to score at least 16 on the Center for Epidemiological Studies-Depression Scale (CES-D), indicating clinically significant depressive symptoms, at least once during the intervention phase (32.3 versus 17.3 percent; odds ratio, 2.5); they also had a higher mean CES-D score across the intervention period. The effect of treatment was moderated by baseline reproductive stage, with the mood benefits of TE+IMP versus placebo seen among women in the early menopause transition but not those in the late menopause transition or among postmenopausal women. ""Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women,"" the authors write.","Baseline estradiol levels, baseline vasomotor symptoms, history of depression, and history of abuse did not moderate treatment effects. CONCLUSIONS Twelve months of TE+IMP were more effective than placebo in preventing the development of clinically significant depressive symptoms among initially euthymic perimenopausal and early postmenopausal women. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01308814",[5],Psychology,train,5.0,news,http://ct.moreover.com/?a=32994759125&p=1pl&v=1&x=bdYZwfFuVnzCThCNC5v8iw
10.1177/0956797610366545,Psychology_easy_491,"In other words, don't throw out those lucky socks just yet.","Participants' authenticity ratings varied across conditions, F(2, 97) = 7.89, p rep = .99.","So, if you believe that something you wore helped achieve a desired outcome in the past, it might be enough to provide an added sense of security and confidence the next time you wear it. In other words, don't throw out those lucky socks just yet. An ""off"" day is precisely the right time to wear whichever garment most reliably rakes in the compliments.","Moreover, as we predicted, counterfeits led to an increase in unethicality: Participants in the counterfeit-sunglasses condition behaved more dishonestly than participants in both the authentic-sunglasses condition and the control condition. Participants' authenticity ratings varied across conditions, F(2, 97) = 7.89, p rep = .99. Participants felt less authentic (i.e., more self-alienated) in the counterfeit-sunglasses condition (M = 4.46, SD = 1.05) than in both the authentic-sunglasses condition (M = 3.65, SD = 0.85, p rep > .99) and the control condition (M = 3.73, SD = 0.82, p rep > .95).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40284974899&p=1pl&v=1&x=dKS-M0S2S7hfLS24C5UejQ
10.1016/j.jsams.2016.11.003,Psychology_easy_494,"Bewegung verbessert die Gehirnleistung Auf der anderen Seite haufen sich die Beweise, dass wir in Bewegung besser denken konnen.",Only the association of MVPA with reading fluency in Grade 2 remained statistically significant after mutual adjustment for MVPA and ST. Further adjustment for reading fluency in Grade 1 attenuated the associations of MVPA or ST in Grade 1 with reading fluency in Grade 2 (P > 0.150) but it had no effect on the relationships of MVPA or ST to reading fluency in Grade 3 (P < 0.030).,",,Es gibt keinerlei wissenschaftliche Grundlage, dass Stillsitzen sich irgendwie positiv auf die Entwicklung der Kinder auswirkt."" Bewegung verbessert die Gehirnleistung Auf der anderen Seite haufen sich die Beweise, dass wir in Bewegung besser denken konnen. So fuhrte etwa der renommierte Sportwissenschaftler Wildor Hollmann von der Sporthochschule Koln mehrere Studien zum Thema Bewegung und Gehirnleistung durch.","However, this association was no longer statistically significant after further adjustment for MVPA, ST, or body fat percentage (P > 0.100). Only the association of MVPA with reading fluency in Grade 2 remained statistically significant after mutual adjustment for MVPA and ST. Further adjustment for reading fluency in Grade 1 attenuated the associations of MVPA or ST in Grade 1 with reading fluency in Grade 2 (P > 0.150) but it had no effect on the relationships of MVPA or ST to reading fluency in Grade 3 (P < 0.030). Furthermore, the relationships of MVPA and ST in Grade 1 to reading and arithmetic skills in Grade 1 were no longer statistically significant after additional adjustment for body fat percentage or 50-m shuttle run test time (P > 0.065).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39504085857&p=1pl&v=1&x=2asyaq5ZliYcfYKbAmYsOg
10.1007/s11292-016-9261-3,Psychology_easy_497,"""There's a lot of officers involved,"" Yokum says.",Our second measure of treatment integrity failure was more detailed.,"What makes the D.C. study especially powerful is that it's one of the biggest police departments in the country. ""There's a lot of officers involved,"" Yokum says. And so, just the numbers here are very large.""","This noncompliance could be either during control shifts, such that officers used the devices when they were not supposed to, or if they were able to decide when to turn devices on during individual encounters (the protocol stated that Bevery^encounter was to be recorded as soon as the officer arrived at the scene). Our second measure of treatment integrity failure was more detailed. Conversely, when officer cameras did not record any amount of data during a shift, this was an indication that the camera had either been left back at the station, or switched off during the shift; we nominally defined a treatment shift without any downloaded footage (0 min or 0 megabytes downloaded) as a protocol violation, as it is unreasonable that any officer on duty would have nil interaction with members of the public in middle or large police departments.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/scientists-hunt-hard-evidence-on-how-cop-cameras-affect-behavior/
10.1016/j.psc.2011.02.002,Psychology_easy_498,The visit didn't go as planned.,"Of all factors examined in PA studies of older adults, psychiatric illness consistently emerges as the most prominent.","The visit didn't go as planned. This was not out of the ordinary -- Adler, like many adoring mothers, always calls her daughter after parting ways. ""Normally I would think, 'Oh that's a sign of suicide,' but it was during my layover,"" Rickard says.","Results indicate that specific factors in domains of psychiatric illness, social connectedness of the older person with his or her family, friends, and community, physical illness and functional capacity appear to influence risk for suicide. Of all factors examined in PA studies of older adults, psychiatric illness consistently emerges as the most prominent. The lessons are clear.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39799907694&p=1pl&v=1&x=a_MjdK-ga4qMWa1qoahlMQ
10.1016/j.neuropharm.2017.12.039,Psychology_easy_499,"That's just not a feasible solution, says Ferrario.","1B : unpaired two-tailed t-test, p ¼ .32; OP: 1.79 sessions ±0.14; OR: 1.53 sessions ±0.13).","Changing behaviors in response to food cues in humans won't be as simple as delivering a drug directly into the brain. That's just not a feasible solution, says Ferrario. ""Part of that is the psychological aspect; they have to exert more effort and take additional steps to avoid unhealthy behaviors.","During FR1 training, obesity-prone and obesity-resistant rats reached the acquisition criterion within a similar timeframe ( Fig. 1B : unpaired two-tailed t-test, p ¼ .32; OP: 1.79 sessions ±0.14; OR: 1.53 sessions ±0.13). When rats were transitioned to a VI schedule of reinforcement, active lever responding increased as a function VI length, as expected ( Fig.",[1],Psychology,train,1.0,news,http://www.futurity.org/obesity-food-cues-1671292/
10.1007/s00429-014-0857-y,Psychology_easy_500,"The researchers stated that these regions of the brain are associated with autism, based on previous studies.",The primary purpose for using this type of threshold is to cut the periphery of the GM and WM area and effectively limit the area for analysis to areas likely to be GM and WM.,"Conversely, white matter volume is greater in the right hippocampus of humanities students than science students. The researchers stated that these regions of the brain are associated with autism, based on previous studies. According to Discover, Takeuchi and his colleagues suggested the results may support psychologist Simon Baron-Cohen's ""empathizing-systematizing"" theory, which explains that some people are more drawn to empathic systems, such as sociology and psychology, while some people find impersonal systems, such as in sciences like physics and chemistry, more appealing.","In the analyses of rGMV and rWMV, we included only voxels that showed rGMV and rWMV values of [0.05 in all subjects. The primary purpose for using this type of threshold is to cut the periphery of the GM and WM area and effectively limit the area for analysis to areas likely to be GM and WM. Voxels outside the brain areas are more likely to be affected by signals outside the brain through smoothing.",[1],Psychology,train,1.0,news,http://guardianlv.com/2014/08/brain-of-humanities-and-science-students-may-be-different/
10.1016/j.obhdp.2016.07.004,Psychology_easy_502,Il n'y a donc rien de mal a utiliser les cristaux.,"For example, basketball players who use pre-shot routines when making free-throw attempts, such as spinning the ball three times and bouncing it once before shooting it, tend to have a higher percentage of successful free-throws than those who do not .",La magie n'est pas dans le cristal : elle est dans votre tete. Il n'y a donc rien de mal a utiliser les cristaux. Des etudes montrent qu'entretenir des rituels avant une performance (comme l'interpretation de Don't Stop Believin' de Journey devant des inconnus dans une soiree karaoke) aide a reduire le stress et peut meme ameliorer le resultat.,"Our research extends prior research by assessing whether completing a ritual can causally reduce preperformance anxiety and thereby enhance task performance. For example, basketball players who use pre-shot routines when making free-throw attempts, such as spinning the ball three times and bouncing it once before shooting it, tend to have a higher percentage of successful free-throws than those who do not . Furthermore, elite basketball athletes, who have higher stakes and perhaps higher anxiety when they play, tend to have more elaborate and longer pre-shot routines than do novice athletes .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38483785139&p=1pl&v=1&x=qKy1PsA7h1wVW91W8kJxhg
10.1111/j.1600-0447.2011.01712.x,Psychology_easy_505,I was also one of the 43% of mental health caregivers who feel that their loved one can turn to other people for support as well.,"While the models from which these coefficients were derived are covariate adjusted, this assumption is unlikely to hold.",I can attest to the high stress levels and poor health that are found in the statistics about caregivers. I was also one of the 43% of mental health caregivers who feel that their loved one can turn to other people for support as well. I was able to push through the stigma surrounding mental illness and reached out to his friends and family to help shoulder the burden.,"Taken together, mental disorders account for a small but meaningful reduction in the proportion of people who marry and increase in the proportion of people in their first marriage who divorce. While the models from which these coefficients were derived are covariate adjusted, this assumption is unlikely to hold. Therefore, estimates of the population attributable risk should be taken as heuristic upper bounds to the likely societal effects of disorders on marriage and divorce.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40147614030&p=1pl&v=1&x=YyG-BhkjCT74OzMYs9LlUA
10.1002/brb3.576,Psychology_easy_506,"RELATED: Best and Worst Foods for Sleep

""That's tantalizing because it suggests that maybe one of the things the short sleepers are doing in the scanner is performing memory consolidation more efficiently than non-short sleepers,"" Dr. Anderson said.","Toward this end, present findings are notable in demonstrating increased connectivity between sensory cortices and bilateral hippocampus and amygdala in short sleepers denying daytime dysfunction, but not in short sleepers reporting daytime dysfunction (Fig.","Those who said they felt fine on shorter sleep schedules also had brain scans that showed enhanced connectivity between parts of the brain associated with external sensory information and memory. RELATED: Best and Worst Foods for Sleep

""That's tantalizing because it suggests that maybe one of the things the short sleepers are doing in the scanner is performing memory consolidation more efficiently than non-short sleepers,"" Dr. Anderson said. If these people are really able to consolidate their memories and brain tasks throughout the day, he explained, perhaps they actually don't need as much sleep at night.","A similar process may be evident in selfreported short sleepers who deny daytime dysfunction, who may seek environmental stimulation as a behavioral strategy to overcome their true level of daytime sleepiness. Toward this end, present findings are notable in demonstrating increased connectivity between sensory cortices and bilateral hippocampus and amygdala in short sleepers denying daytime dysfunction, but not in short sleepers reporting daytime dysfunction (Fig. 5 ).",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/the-truth-about-people-who-brag-they-dont-need-much-sleep/
10.1177/0956797614567339,Psychology_easy_508,"Notably, though, four types of proficiencies didn't fully ripen until people were in their 50s: vocabulary, math, general knowledge, and comprehension (a test that involved explaining why things are the way they are--for example, why we have a parole system):

Age of Peak Performance on Various Types of Tests - Central lines represent medians; whiskers represent 95% confidence intervals (Psychological Science)

Changes in Test Performance Over Lifespan (Psychological Science)

This article was originally published on www.theatlantic.com.",This provides additional evidence that Internet-based testing methods and traditional testing procedures yield similar results (cf.,"They found that most of the skills peaked in the subjects' late teens and early 20s. Notably, though, four types of proficiencies didn't fully ripen until people were in their 50s: vocabulary, math, general knowledge, and comprehension (a test that involved explaining why things are the way they are--for example, why we have a parole system):

Age of Peak Performance on Various Types of Tests - Central lines represent medians; whiskers represent 95% confidence intervals (Psychological Science)

Changes in Test Performance Over Lifespan (Psychological Science)

This article was originally published on www.theatlantic.com. ""Image of ""lady"" via Shutterstock","Thus, the different results for these tasks cannot be explained by differences between Internetbased and in-person testing nor by cohort effects (see discussion of Fig. This provides additional evidence that Internet-based testing methods and traditional testing procedures yield similar results (cf. Notably, however, Vocabulary age of peak performance was later for the Internet-based sample (~65 years) than for the WAIS-III sample (~50 years).",[1],Psychology,train,1.0,news,http://www.theepochtimes.com/n3/1287627-the-smartest-age/
10.1080/17470919.2016.1257437,Psychology_easy_510,Many were in tears by the end of the scan.,Activation of the medial prefrontal cortex in all three tasks may suggest a role in representation of affective meaning for the religious stimuli and suggests that cognitive attribution and judgment of the meaning or value of religious stimuli contributes to their experience.,"The findings will be published Nov. 29 in the journal Social Neuroscience. Many were in tears by the end of the scan. Based on fMRI scans, the researchers found that powerful spiritual feelings were reproducibly associated with activation in the nucleus accumbens, a critical brain region for processing reward.",The dorsal anterior cingulate cortex in particular may contribute to the perception of salience of religious experience . Activation of the medial prefrontal cortex in all three tasks may suggest a role in representation of affective meaning for the religious stimuli and suggests that cognitive attribution and judgment of the meaning or value of religious stimuli contributes to their experience. A role for the ventromedial prefrontal cortex in shaping belief is also supported by evidence that neuromodulation of this regions can specifically decrease endorsement of religious beliefs .,[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/7rZ8a3OxIcQ/
10.1016/j.neuron.2012.06.016,Psychology_easy_511,"""It's best not to do nothing with your brain.""","However, we also calculated the number of PV-expressing cells with weak or strong expression and the results were not different (data not shown).","The findings make a case for teaching mindfulness and cognitive behavioral therapy. ""Experience can change outcomes in really profound ways,"" Fenton says. ""It's best not to do nothing with your brain.""","This view acknowledges that schizophrenia may turn out to be heterogeneous and that multiple factors contribute, which include genetic alterations, infectious, toxic, and stressful events. However, we also calculated the number of PV-expressing cells with weak or strong expression and the results were not different (data not shown). This physiological hypothesis is agnostic to etiology of the disease and to whether there are abnormalities in dopaminergic, glutamatergic, GABAergic, or other neurotransmitter systems.",[1],Psychology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=head-start-early-learning-cognitive
10.1177/0956797618780643,Psychology_easy_513,"Once we find a path that intrigues us and brings success, we may curb or even abandon exploration of other potential interests.","Because the current study was conducted online, we expected that the less controlled setting would result in a relatively smaller effect size.","First, it implies that our interests and talents may be narrow or specific. Once we find a path that intrigues us and brings success, we may curb or even abandon exploration of other potential interests. Second, we may expect pursuit of our one true passion to be easy - after all, this is the pathway that will provide endless drive and excitement, and will yield the greatest achievement.","Our presumed medium-sized effect was based on the effect obtained in the prior study, which yielded a large effect size yet was conducted in a more controlled setting. Because the current study was conducted online, we expected that the less controlled setting would result in a relatively smaller effect size. Greater openness to experience might predict greater interest in the mismatching article.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37339115261&p=1pl&v=1&x=Rq5YXhL1b6gHjgtzmSKWWA
10.1080/19325037.2017.1343161,Psychology_easy_515,"Finding new ways to motivate young people is vital for long-term health, and - for a generation tethered to their mobiles - fitness devices seemed to be a new and exciting way to help.","Cronbach's alpha levels for all subscales at pre-and posttest exceeded .70, meeting acceptable criteria (Table 1) .","Finding new ways to motivate young people is vital for long-term health, and - for a generation tethered to their mobiles - fitness devices seemed to be a new and exciting way to help. Their research with school pupils aged 13-14 showed that wearing a FitBit for eight weeks demotivated the teenagers from exercising rather than encouraging them to do more. Surveys and focus groups conducted before and after the trial period concluded that the device (in this case, the FitBit Charge wristband and app, which retails for around PS100) ultimately made participants feel less confident about their competence at exercising, less connected to their peers, and less like they had autonomy or choice over how to engage with physical activity.","."" Cronbach's alpha levels for all subscales at pre-and posttest exceeded .70, meeting acceptable criteria (Table 1) . No strong disagreements between the authors occurred during this process.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/fashionable-fitbits-discourage-young-teens-from-exercising-study-finds/
10.1186/s12889-017-4675-z,Psychology_easy_516,"That share was up from 5% in 2016, and 3.3% in 2000.","In the domain of purpose in life, the participants indicated three specific motives for remaining in the work force.","That share was up from 5% in 2016, and 3.3% in 2000. For example, a WFH employee can spend their lunch hour running errands, while a WFA employee can do that and also move to a location closer to family and/or with a lower cost of living. The results revealed that examiners' work output spiked by 4.4% after transitioning to a WFA program.","Now I can save more money and I can spend it on travelling.' In the domain of purpose in life, the participants indicated three specific motives for remaining in the work force. You are not standing on the sideline, which is something what happens if you are ageing.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40167531853&p=1pl&v=1&x=KKYJH4Z2xzXXCWZQlX5dkw
10.1073/pnas.1018601108,Psychology_easy_517,"Essentially, wisdom adds the context that intelligence needs in order to be useful.","If indeed test takers are less than maximally motivated in low-stakes research settings, material incentives should substantially improve their performance.","Despite the efficiency and productivity that intelligence promises, it is wisdom that leads us into real fulfillment. Essentially, wisdom adds the context that intelligence needs in order to be useful. For example, if you are looking for a life partner and have no intention of moving from your hometown, you probably want to date people who have similar geographic plans.","This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10. If indeed test takers are less than maximally motivated in low-stakes research settings, material incentives should substantially improve their performance. In 46 independent samples (n = 2,008), the mean effect of material incentives on IQ was medium to large: g = 0.64 [95% confidence interval (CI) = 0.39, 0.89], P < 0.001.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34198718938&p=1pl&v=1&x=aIUR5Rq6-RNuCCJqOqQASg
10.1016/j.neuroimage.2017.03.061,Psychology_easy_518,"""It's a lot like sending ripples through a still pond - if there's some large thing like a boulder under the surface, the ripples are going to displace around it,"" Schwarb said.","As in the previous work, we did not find a significant relationship between SR performance and hippocampal stiffness (μ; r=−0.09, p=0.542).","The vibration is the key to measuring the structural integrity of the hippocampus. ""It's a lot like sending ripples through a still pond - if there's some large thing like a boulder under the surface, the ripples are going to displace around it,"" Schwarb said. The study, published in the journal NeuroImage, found that those who performed better on the fitness test tended to also perform better on the memory task, confirming a correlation the group had noticed before.","The current work extends this finding by replicating this relationship with a larger, more heterogeneous sample of young men and women. As in the previous work, we did not find a significant relationship between SR performance and hippocampal stiffness (μ; r=−0.09, p=0.542). Indeed, in our sample, caudate ξ′ was not significantly correlated with relational memory performance, r=.10, p=.486.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/pn-00k6OsqU/
10.1002/acp.2897,Psychology_easy_519,But it's a small price to pay.,"Participants varied in the number of songs that they reported mentally replaying during the maze task: 24.7% reported that no songs replayed, 41.6% reported only one song (usually the third), 19.1% reported that two songs replayed for some period, and 14.6% reported that all three songs replayed for some portion of the maze task.","Solving anagrams might not always be the best way to spend your time, sure. But it's a small price to pay. And -- this is crazy -- much, much better than having ""Call Me Maybe"" stuck in your head all day.","Tukey's comparisons indicated that the third song replayed more (M = 43.37, SD = 38.52) than either the first (M = 6.40, SD = 16.18) or second song (M = 8.54, SD = 18.50). Participants varied in the number of songs that they reported mentally replaying during the maze task: 24.7% reported that no songs replayed, 41.6% reported only one song (usually the third), 19.1% reported that two songs replayed for some period, and 14.6% reported that all three songs replayed for some portion of the maze task. We also found that song order influenced whether or not the song returned during the 24 hours after the experiment, F(2, 70) = 13.670, MSE = 0.185, p < .001, partial eta 2 = .281.",[1],Psychology,train,1.0,news,http://www.theatlantic.com/technology/archive/2013/03/how-to-get-beyonc-out-of-your-head-the-scientific-solution/274333/
10.1080/10852352.2010.486297,Psychology_easy_521,"It's not a mere logistical challenge, but an intense feeling as well.","While outside the scope of the present study, it is conceivable that parent involvement may influence the child's perception of cognitive competence by means described by .","Writing the last chapter of her dissertation, parenting two boys under three, and looking for a post-PhD job all the time is not a task for the faint of heart. It's not a mere logistical challenge, but an intense feeling as well. She also stated that ""One unexpected benefit of this time, however, has been the opportunity to reflect upon how the past seven years of graduate have molded me.","This finding is consistent with previous studies . While outside the scope of the present study, it is conceivable that parent involvement may influence the child's perception of cognitive competence by means described by . Findings demonstrated that increased parent involvement was significantly related to increased quality of the student-teacher relationship.",[1],Psychology,train,1.0,news,http://www.parentherald.com/articles/93210/20161210/raising-method-practice-teaching-kids-life-impacts-graduate-school-experience.htm
10.1111/ejn.12173,Psychology_easy_522,"Their performance was improved after listening to music -- classical or not -- that made them more aroused and made them feel better, based on personal preferences.","The interregional analysis also identified three positively correlated longrange connections, including HG to IFG, HG to SMG, the frontoparietal IFG to SMG connection, as well as one negatively correlated long-range connection, PP to the PGp division of the AG.","The feelings music conjures can actually improve your performance on cognitive tasks, Grahn explains. Their performance was improved after listening to music -- classical or not -- that made them more aroused and made them feel better, based on personal preferences. This ability of music then to make us feel good brings with it its own benefits.","Additionally, the results also indicated highly synchronized responses among auditory cortical regions of superior temporal cortex, including HG, PP, PT and pSTG. The interregional analysis also identified three positively correlated longrange connections, including HG to IFG, HG to SMG, the frontoparietal IFG to SMG connection, as well as one negatively correlated long-range connection, PP to the PGp division of the AG. The results show that interregional synchronization is similar between the Natural Music and Spectrally-Rotated conditions but, consistent with ISS results, inter-regional synchronization is sharply reduced in the PhaseScrambled control condition.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/your-brain-music-how-our-brains-process-melodies-pull-our-heartstrings-271007
10.1080/09687599.2018.1497950,Psychology_easy_523,Both Price and Daley see this as more than just making music.,"As already described, 11 articles fulfilled the reviews inclusion criteria.","They're universally catchy, and weird and wonderful."" Both Price and Daley see this as more than just making music. The sessions act as a way of empowering people, encouraging them to talk about their lives, build confidence and form bonds with others.","Furthermore, greater levels of generalisability could be provided by drawing on a wider range of participants and settings. As already described, 11 articles fulfilled the reviews inclusion criteria. The vast majority of the studies employed a range of qualitative techniques (e.g.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38404745678&p=1pl&v=1&x=Vcy5Da45MYrS-5QgiTODlQ
10.1073/pnas.1404396111,Psychology_easy_524,"""A professor might first get them thinking about the properties of electricity,"" explained Preston.","We found two regions for which FFA connectivity tracked more with BC than XY performance: one in left [Montreal Neurological Institute (MNI) template coordinates (in millimeters) x, y, z = −16, −30, −19] and one in right (14, −33, −11) HPC, extending into parahippocampal cortex (PHC) ( Fig.","Researchers will next try their experiment on children, as the results may have significant implications for modern education strategies. ""A professor might first get them thinking about the properties of electricity,"" explained Preston. ""By prompting them beforehand, the professor might help them reactivate relevant knowledge and make the new material more digestible for them.""","There was no relationship between FFA-HPC connectivity during post-AB rest and XY performance (SI Methods and Results, Timeseries correlation analysis). We found two regions for which FFA connectivity tracked more with BC than XY performance: one in left [Montreal Neurological Institute (MNI) template coordinates (in millimeters) x, y, z = −16, −30, −19] and one in right (14, −33, −11) HPC, extending into parahippocampal cortex (PHC) ( Fig. An overlapping cluster (−18, −29, −13) in the left hemisphere was found to predict BC performance ( Fig.",[1],Psychology,train,1.0,news,http://www.upi.com/Science_News/2014/10/22/Mental-rest-and-reflection-key-to-better-learning/3741413990485/
10.1007/s10608-012-9476-1,Psychology_easy_527,"For example, some of the ancient Stoics were in fact enslaved.","Overall, CBT for bipolar disorder was an effective method of preventing or delaying relapses (e.g., .","A Stoic (or ) approach would not suggest we blame our problems with ourselves on not being ""believed in"" sufficiently by other people (or on not ""believing in"" other people sufficiently, for that matter). For example, some of the ancient Stoics were in fact enslaved. And so, says the Stoic Epictetus, we should not hold ourselves responsible for them nor see ourselves reflected in them.","There is little evidence that CBT as a stand-alone treatment (rather than as an adjunct to pharmacotherapy) is effective for the treatment of bipolar disorder. Overall, CBT for bipolar disorder was an effective method of preventing or delaying relapses (e.g., . Furthermore, the efficacy of CBT at preventing relapse did not seem to be influenced by the number of previous manic or depressive episodes.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34338621785&p=1pl&v=1&x=-xAIwZHvTk0QWM0cGRwFLA
10.1002/hbm.22310,Psychology_easy_528,The area of the foot artistsa brains thatas normally associated with hand control showed a significant level of correlation with their feet.,"The interaction between fingertip ROI and stimulation condition was highly significant (F 16,80 5 71.7, P < 10",But the unique attributes of these artistsa brains didnat end there. The area of the foot artistsa brains thatas normally associated with hand control showed a significant level of correlation with their feet. The researchers write that this indicates the artistsa brains appear to have adapted to accommodate the absence of hands.,"Figure 2C plots the magnitude parameter estimates of the fixed HRF GLM model for each fingertip stimulation condition in each ROI averaged across subjects, confirming this pattern of maximum magnitude estimates for the fingertip stimulation corresponding to the ROI, and significantly larger than baseline responses for up to four adjacent fingertip stimulation conditions. The interaction between fingertip ROI and stimulation condition was highly significant (F 16,80 5 71.7, P < 10 , Greenhouse-Geisser correction: F 1,5 5 71.7, P < 10 23 ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40159795211&p=1pl&v=1&x=nRTQZnBaI0rhe-4KFDgu4g
10.1037/a0034209,Psychology_easy_529,"Perhaps most exciting, added Rogge, is that this self-help exercise could open new possibilities for nurturing nuptial ties on a broad scale.","In short, although counterarguments make it less plausible, unmeasured factors may be generat- This article is intended solely for the personal use of the individual user and is not to be disseminated broadly.","And for five movies to give us a benefit over three years--that is awesome."" Perhaps most exciting, added Rogge, is that this self-help exercise could open new possibilities for nurturing nuptial ties on a broad scale. If couples can do this on their own, it makes it so much easier to help them,"" he said.","If the NoTx couples were at elevated risk for adverse outcomes, it seems likely that more and stronger differences in relationship satisfaction would have emerged. In short, although counterarguments make it less plausible, unmeasured factors may be generat- This article is intended solely for the personal use of the individual user and is not to be disseminated broadly. ing differences between the NoTx group and the remaining groups.",[1],Psychology,train,1.0,news,http://www.newswise.com/articles/divorce-rate-cut-in-half-for-newlyweds-who-discussed-five-relationship-movies
10.1016/j.jesp.2015.04.008,Psychology_easy_530,"If this ploy works, it divides groups that might otherwise form a more united and more potent resistance.",The completion rate was 64% (614 persons began the study).,"That's why they highlight these differences while downplaying similarities in the concerns and aspirations we all share. If this ploy works, it divides groups that might otherwise form a more united and more potent resistance. What makes these they're-different-from-us appeals psychologically effective is that we tend to view ingroup members more favorably than outgroup members.","Apart from these two pairs there is no special conflict between the teams, aside from that which arises from regular competition in the same league (e.g., there is no particular conflict between BD and BL; see Fig. The completion rate was 64% (614 persons began the study). Participants' mean age was 35 years (SD = 12.46; completed by 275 participants) and 14% were female (completed by 274 participants).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34327811009&p=1pl&v=1&x=oyK4Z_lYTWRwMlPCCBtzAg
10.1038/s41562-018-0434-0,Psychology_easy_531,It's important to shift the focus from trying to change what people believe to reinforcing what their friends believe.,"Thus, smaller states were less likely to meet our minimum sample size criteria (linear regression of state population predicting the minimum threshold of at least 50 survey participants, with robust standard errors: coeff=2.8 X 10-8, p=.043).","""Instead, the roadmap to improving perceptions of conservation starts with reminding individuals that their neighbors care about it. It's important to shift the focus from trying to change what people believe to reinforcing what their friends believe. """"Many of us generally agree that reducing energy consumption is needed to help the environment and save our planet -- but we have found that to make it happen, we need to believe that others care about it too,"" said Professor Oliver Hauser of the University of Exeter Business School.","Unsurprisingly, the number of survey respondents in our sample was proportional to a state's population (linear regression of state population predicting number of survey respondents, with robust standard errors: coeff=2.73 X 10-6, p=.020). Thus, smaller states were less likely to meet our minimum sample size criteria (linear regression of state population predicting the minimum threshold of at least 50 survey participants, with robust standard errors: coeff=2.8 X 10-8, p=.043). Our main analysis focuses on states where we have at least 50 participants; however, when we include participants from all 27 states, the results are qualitatively similar.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37834567855&p=1pl&v=1&x=dFrf7NgXrupj3tjKP5kb4Q
10.1080/02640414.2017.1339904,Psychology_easy_532,"Our findings suggest that changing habits in the workplace could be an appropriate place to start, given how much time we spend sitting there every day,"" says Tessa Strain.",This was because the two categories were reciprocals.,"Men spend less time in front of a screen as they get older, with women peaking in middle-age. We need to tackle high levels of sedentary time in early and middle age, when patterns may develop. Our findings suggest that changing habits in the workplace could be an appropriate place to start, given how much time we spend sitting there every day,"" says Tessa Strain.",Only one regression analysis was performed on the relative contributions of the categories of behaviours of weekday ST amongst non-workers and for weekend day ST. This was because the two categories were reciprocals. The analyses stratified by work status were an exception to this as there were not sufficient numbers in the oldest age group amongst those in employment to make meaningful comparisons.,[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/middle-aged-found-to-be-as-sedentary-as-pensioners/
10.3109/07420528.2014.925470,Psychology_easy_533,(Obviamente no estoy recomendando que dejen de usar condones por la sensacion).,"Namely, exogenous melatonin in rats enhanced sexual behavior and attenuated the effects of chronic stress on sexual behavior .","Si era una buena manera de despertar con energia, y me encanta la sensacion de tener semen escurriendome lentamente a lo largo del dia. (Obviamente no estoy recomendando que dejen de usar condones por la sensacion). Nicole tiene una respuesta muy simple: programacion.","The observed evening peak in sexual activity might also be related to an endogenous evening increase in melatonin production. Namely, exogenous melatonin in rats enhanced sexual behavior and attenuated the effects of chronic stress on sexual behavior . Moreover, exogenous melatonin might have different effects on sexual function than the endogenous phasic elevation of melatonin levels during evening/night hours.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33330220158&p=1pl&v=1&x=GAH-MgCx7njtIU2ob0WlZQ
10.1177/0004867415575379,Psychology_easy_535,"""These findings highlight the need for practitioners to inquire into any exposure to childhood trauma during clinical assessments of patients with early psychosis.","This sample consisted of 62 men and 38 women with a mean age of 21.4 years (SD = 2.28, range = 17-26 years) and a median DUP of 4 weeks (SD = 44.4, range = 1-266 weeks).","This may be due to appropriate support being provided to individuals from outpatient services."" ""These findings highlight the need for practitioners to inquire into any exposure to childhood trauma during clinical assessments of patients with early psychosis. Treating psychological distress needs to be a priority for clinicians, rather than managing only psychotic symptoms.","One hundred and six patients consented to participate; however, only 100 completed all measures and were included in final analysis. This sample consisted of 62 men and 38 women with a mean age of 21.4 years (SD = 2.28, range = 17-26 years) and a median DUP of 4 weeks (SD = 44.4, range = 1-266 weeks). Eighty-seven percent were single, 76% were born in Australia and 93% had no dependents.",[1],Psychology,train,1.0,news,http://www.futurity.org/childhood-trauma-psychosis-885482/
10.1016/j.neuron.2010.11.045,Psychology_easy_537,Think about that next time you reach for the remote.,"There was a large spread around this mean, with a standard deviation of 370 ms.","Rather than free will being the ability to do anything at all, it might be an act of selection from the present range of options. And the decision might be made before you are even aware of it. Think about that next time you reach for the remote.","This relatively simple linear algorithm predicted W to occur, on average, 152 ms prior to the actual reported W (median = 100 ms prior to the reported W). There was a large spread around this mean, with a standard deviation of 370 ms. This spread seems to be consistent with our coarse estimations of the inaccuracies in the behavioral report of W times discussed above ( Figure S4D ).",[1],Psychology,train,1.0,news,http://www.scientificamerican.com/article.cfm?id=how-free-is-your-will
10.1073/pnas.1316449110,Psychology_easy_538,"""Any fundamental similarity between humans and bonobos probably traces back to their last common ancestor, which lived around six million years ago.""","2 ; U = 4.0, P = 0.024) and initiated play interactions with others more than twice as frequently compared with orphans ( Fig.","""This makes the species an ideal candidate for psychological comparisons,"" says de Waal. ""Any fundamental similarity between humans and bonobos probably traces back to their last common ancestor, which lived around six million years ago."" ""By measuring the expression of distress and arousal in great apes, and how they cope, we were able to confirm that efficient emotion regulation is an essential part of empathy.","Mother-reared juveniles also spent more than twice as much of their time engaged in social play compared with orphans ( Fig. 2 ; U = 4.0, P = 0.024) and initiated play interactions with others more than twice as frequently compared with orphans ( Fig. 2 ; U = 2.0, P = 0.009).",[1],Psychology,train,1.0,news,http://www.natureworldnews.com/articles/4440/20131014/young-bonobos-regulate-emotions-humans.htm
10.1073/pnas.1601443113,Psychology_easy_539,Don't forget to share on Facebook!,"In contrast to preschool support, there was no significant change in total hippocampus volume over time as a function of school-age maternal support (B = −0.0001, SE = 0.0011, t = −0.10, P = 0.9228).",Did you find this article helpful? Don't forget to share on Facebook! Bonus: Check out this short film about a mother's love.,"S1 shows estimated trajectories of total hippocampus volume by preschool maternal support. In contrast to preschool support, there was no significant change in total hippocampus volume over time as a function of school-age maternal support (B = −0.0001, SE = 0.0011, t = −0.10, P = 0.9228). The school-age maternal support by time interaction in that model was still not significant (B = 0.0012, SE = 0.0011, t = 1.12, P = 0.2647).",[1],Psychology,train,1.0,news,http://www.parentherald.com/articles/39810/20160428/nothing-greater-mother-s-love-simple-motherly-make-kids-smarter.htm
10.1086/678958,Psychology_easy_540,"If you're trying to lose weight, Weight Watchers might seem like the ideal place to share advice and get support.","Nevertheless, we did observe a significant negative trend.","If you're trying to lose weight, Weight Watchers might seem like the ideal place to share advice and get support. All of the members in an early stage of weight loss talked about companionship and felt close to and willing to help other members compared with fewer than half in the advanced stage (42%). In contrast, the vast majority in an advanced stage of weight loss felt distant and were reluctant to share information with other members (79%), compared with less than half in the early stage (44%).","As participants remained strangers throughout the walking program, the variation in the repeated closeness scores was expectably low in this field experiment (the average closeness score changed from 5.37/10 on day 1 to 4.84/10 on day 7). Nevertheless, we did observe a significant negative trend. .01, p .09), which fitted 2 h p a significant negative trend (F(1, 42) p 5.50, p !",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/01/150121115015.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1177/0956797613501884,Psychology_easy_541,Another study showed that participants who watched the awe-inspiring clips became increasingly intolerant of uncertainty.,Eighteen participants were excluded from analyses for failing attention checks.,"This effect held even when awe-inspiring but impossible scenes, such as a massive waterfall through city streets, were presented. Another study showed that participants who watched the awe-inspiring clips became increasingly intolerant of uncertainty. This particular mindset -- a discomfort with uncertainty -- may explain why feelings of awe produce a greater belief in the supernatural.","Consequently, a successful replication of the results of Study 1 would provide further evidence that the effect of awe on agency detection cannot be explained by an association between natural beauty, or any other particular property of the stimuli used, and belief in the power of a creator. Eighteen participants were excluded from analyses for failing attention checks. Replicating previous effects, results showed that condition predicted awe (positivity: M = 2.55; awe: M = 4.66), t(92) = 6.43, p < .001, as well as belief in supernatural control (positivity: M = 4.58; awe: M = 5.79), t(92) = 2.15, p = .035.",[1],Psychology,train,1.0,news,http://www.healthcanal.com/mental-health-behavior/45215-experiencing-awe-increases-belief-in-the-supernatural.html
10.1177/0146167206288599,Psychology_easy_542,"Little says you can downplay certain aspects, and increase or decrease them to some degree, but it'll be an ongoing effort because personalities eventually stabilize by that age.","Using that model, Costa and McCrae (1992c) projected that the median stability of GZTS true scores after 50 years would be .60, and concluded that ""about three-fifths of the variance in personality traits is stable across the full adult age range"" (p. 182).","If you're over the 30 mark and don't like one of your core traits, there's a good chance you're stuck like that. Little says you can downplay certain aspects, and increase or decrease them to some degree, but it'll be an ongoing effort because personalities eventually stabilize by that age. Our maturity levels are also pretty set in stone by the time we reach 30 -- if you still have time and want to improve yourself, practice becoming better until you hit the deadline.","Retest correlations are typically lower over longer retest intervals-for example, the median retest correlation for GZTS scales after 6 years was .77; after 24 years it was .65 (Costa & McCrae, 1992c )-and researchers have typically assumed an exponential decay of consistency (e.g., . Using that model, Costa and McCrae (1992c) projected that the median stability of GZTS true scores after 50 years would be .60, and concluded that ""about three-fifths of the variance in personality traits is stable across the full adult age range"" (p. 182). pointed out that the exponential decay model predicts that eventually rank-order consistency will decline to zero unless there are developmental constancy factors (such as one's unchanging genetic endowment) that force consistency to a non-zero asymptote.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/reinvent-yourself-do-it-you-turn-30-and-your-personality-plateaus-312624
10.1111/acer.12673,Psychology_easy_543,The scientists all agree more research is needed.,"The distribution of this variable was right-skewed at both waves, so we transformed the variable to normalize its distribution.","However, the genetic component is greatly influenced by socioeconomic factors. The scientists all agree more research is needed. However, they hope to find a link that will help doctors identify patients who are in danger of becoming alcoholics.","Mean age at this time was 54 years (SD = 12, range = 34 to 82). The distribution of this variable was right-skewed at both waves, so we transformed the variable to normalize its distribution. At wave 1, a natural-log transformation was most effective at normalizing the distribution, while at wave 2 a square-root transformation yielded the best result.",[1],Psychology,train,1.0,news,http://www.inquisitr.com/2222372/alcoholism-eye-color/
10.1016/j.bandl.2012.04.010,Psychology_easy_545,"Their newer article also puts forth several possible reasons why the VOF region got lost in the first place:

1) The VOF didn't conform to what people expected the brain to look like at the time.",4) .,"Their newer article also puts forth several possible reasons why the VOF region got lost in the first place:

1) The VOF didn't conform to what people expected the brain to look like at the time. (If Wernicke's name sounds familiar, it's because he has a brain area named after him: Wernicke's area, which is critical for speech.) The VOF is a bundle of neurons connecting two other areas together, but it was oddly oriented.","Hence it is unlikely that imaging artifacts affect the identification of major white matter fascicles projecting to the VWFA; however cortical endpoints in the anterior temporal lobe may be masked by signal loss in cortex. 4) . The fascicular network near the VWFA contains projections capable of communicating efficiently with specific regions within the anterior temporal lobe, frontal lobe, and lateral occipital-parietal cortex.",[1],Psychology,train,1.0,news,http://www.vox.com/xpress/2014/11/20/7251173/lost-brain-region-found
10.1111/jcc4.12063,Psychology_easy_546,"""But I think that's changing with how we use email for everything these days.""","Jeg har sikkert blingset vedr signatur, så der har du sikkert rett :-)","They found three primary uses: to express positive vibes, to mark jokes, and lastly to either strengthen or soften statements that could be misread as reprimanding. ""But I think that's changing with how we use email for everything these days."" ""Casual communication is a perfectly valid type of office communication that's always existed,"" says Schwalbe.","Thanks for your help -and now I promise that I have contacted you for the last time concerning this case:-) Jeg har sikkert blingset vedr signatur, så der har du sikkert rett :-) I have probably read the signature incorrectly, so there you're probably right :-)",[1],Psychology,train,1.0,news,http://www.theatlantic.com/business/archive/2015/05/why-emoji-are-suddenly-acceptable-at-work/393191/
10.1177/0956797611430953,Psychology_easy_547,"Now, Warriner said, they're becoming increasingly virulent and seem to be specially adapted to contaminate vegetables and other produce, along with water, and now flour.",Figure 1 displays mean prevalence estimates for the three types of responses in the BTS condition (the admission estimates were capped at 100%; they exceeded 100% by a small margin for a few items).,"This is the first multi-provincial outbreak of E.coli O121 in Canada. Now, Warriner said, they're becoming increasingly virulent and seem to be specially adapted to contaminate vegetables and other produce, along with water, and now flour. Warriner said it could happen in the wheat fields, where both animal and human waste is used as fertilizer.","These correlations were more modest when Item 10 (""Falsifying data"") was excluded (odds ratio with baseline self-admission rate: nonparametric correlation = −.48, p < .20; parametric correlation = −.59, p < .10; odds ratio with defensibility rating: nonparametric correlation = −.57, p < .12; parametric correlation = −.59, p < .10). Figure 1 displays mean prevalence estimates for the three types of responses in the BTS condition (the admission estimates were capped at 100%; they exceeded 100% by a small margin for a few items). The figure also shows the geometric means of all three responses; these means, in effect, give equal credence to the three types of answers.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/cook-your-cookies-plus-closing-the-gown-gap/
10.1016/j.appet.2014.10.004,Psychology_easy_548,"Cauliflower could be used instead of potatoes too, but there's no need to avoid spuds entirely, Henderson says.","Moreover, when administered by weight control experts, as opposed to graduate student trainees, weight loss was significantly higher in ABT than standard behavioral treatment at 6-month follow-up (11.0% vs. 4.8).","To cut back on calories and saturated fat, use 2 percent milk and extra-virgin olive oil instead of butter and cream, O'Keeffe recommends. Cauliflower could be used instead of potatoes too, but there's no need to avoid spuds entirely, Henderson says. ""In other parts of the world, gluten, dairy and white potatoes may be frowned upon as 'unhealthy' foods,"" she says, ""but to me, they are much more wholesome than so many of the highly-processed foods that we eat in America - even if they are labeled as 'healthy.'""","Weight loss at 18 months, i.e., 6-month follow-up, was somewhat larger for those receiving ABT, but moderation analyses revealed that this advantage was especially powerful for participants with particular vulnerabilities, i.e., mood disturbance, elevated responsivity to food cues and high disinhibition . Moreover, when administered by weight control experts, as opposed to graduate student trainees, weight loss was significantly higher in ABT than standard behavioral treatment at 6-month follow-up (11.0% vs. 4.8). This result raises the possibility that those who have more experience in administering behavioral weight control interventions may be more successful at integrating acceptance-based principles into the behavioral program.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33564975774&p=1pl&v=1&x=Hj87IOFU8uq551PZEFa4qQ
10.1146/annurev-psych-010213-115057,Psychology_easy_550,The clearest example of this is our tendency to glorify fearless risk-taking in leaders.,"Adm. 2009), and, depending on the study, boys with ADHD outnumber girls by 2:1 to 9:1 (Rucklidge 2010).","To be sure, just because someone is full of themselves and talks a lot during meetings doesn't mean we should assume that they are leadership material. The clearest example of this is our tendency to glorify fearless risk-taking in leaders. In contrast, individuals who see leadership as a resource for their teams and subordinates -- a psychological competency that turns a group of individuals into a high-performing unit -- will not just be more humble, modest, and altruistic, but also act with integrity.","Overall, then, although leadership is stereotyped as masculine, there is no evidence that women are incompetent as leaders, whether measured by effectiveness or by the use of optimal styles such as transformational leadership. Adm. 2009), and, depending on the study, boys with ADHD outnumber girls by 2:1 to 9:1 (Rucklidge 2010). An analysis by ethnicity for US samples showed that the magnitude of the gender difference was d = 0.20 among whites but −0.04 among blacks.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38866062596&p=1pl&v=1&x=tS4tYcKB6KJ8hbGaMQfZmA
10.1093/cercor/bhq021,Psychology_easy_551,Perhaps you begin your commute home and remember that you need to pick up milk.,6 ) and that the control RTs would be relatively flat as a function of distractor processing.,"Perhaps you begin your commute home and remember that you need to pick up milk. But then immediately, another to-do springs to mind: You never called back your friend last week. But this new model speaks to what happens when multiple memories are coexisting front and center in our minds, in a place called ""working memory.""","Thus, the effect of subtracting ignored repetition RTs from control RTs was to isolate the effect of stimulus repetition on RTs, unconfounded by other factors that might be shared across the 2 conditions. 6 ) and that the control RTs would be relatively flat as a function of distractor processing. However, this is not the pattern that we found.",[1],Psychology,train,1.0,news,http://www.npr.org/sections/health-shots/2015/07/11/421749669/trying-to-remember-multiple-things-may-be-the-best-way-to-forget-them
10.1073/pnas.1802246115,Psychology_easy_552,"""Our results indicate that neural abnormalities in many people with DP are more widespread than previous studies have suggested,"" says senior author Bradley Duchaine , a professor of psychological and brain sciences and the principal investigator of the Social Perception Lab at Dartmouth College.",In Fig.,"""Our results indicate that neural abnormalities in many people with DP are more widespread than previous studies have suggested,"" says senior author Bradley Duchaine , a professor of psychological and brain sciences and the principal investigator of the Social Perception Lab at Dartmouth College. This is the first study of DP to use videos of moving faces and is more in line with how one experiences the world, rather than relying on static images of faces. It is also the first fMRI study of its kind to investigate activity in scene and body areas.","This method provided a simple but effective way to balance the trade-off between extent and selectivity and ensured a fair comparison between controls and DPs. In Fig. 1A , each of the category-selective significance maps shows the clusters that were more responsive to either faces, scenes, bodies, or objects than the contrast category.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34395450935&p=1pl&v=1&x=DY9URZpCSq4Abx-nzv5r-A
10.1073/pnas.1409411111,Psychology_easy_554,"The average age of the children at adoption was 12.8 months, which meant that they were likely to have learned to recognize tone before being adopted.","There were no statistically significant differences in reaction time for either the lexical tone, F(2, 27) = 2.76, P = 0.081, or the hum, F(2, 27) = 1.98, P = 0.157, conditions.","The average age of the children at adoption was 12.8 months, which meant that they were likely to have learned to recognize tone before being adopted. All of the children were able to answer with very high accuracy, and there were no differences between the groups on either accuracy or reaction times. However, their fMRI scans showed a difference in how they processed the information.","Participants also responded with similar reaction times in both the lexical tone (mean bilingual, 334.4 ms; mean monolingual, 338.1 ms; mean IA, 212.0 ms) and the hum (mean bilingual, 319.9 ms; mean monolingual, 306.3 ms; mean IA, 224.1 ms) conditions. There were no statistically significant differences in reaction time for either the lexical tone, F(2, 27) = 2.76, P = 0.081, or the hum, F(2, 27) = 1.98, P = 0.157, conditions. Accuracy and reaction time results are discussed further in SI Methods.",[1],Psychology,train,1.0,news,http://arstechnica.com/science/2014/11/lost-languages-leave-traces-on-the-brain/
10.1038/s41386-019-0369-9,Psychology_easy_556,"This led to a significant reduction of ratings of depression severity in all patients, it was reduced by half on average.","Moreover, the heavy anisotropy which surrounds a contact that is located in white matter stops the electric field to expand far away from the electrode.","This led to a significant reduction of ratings of depression severity in all patients, it was reduced by half on average. For half of the study participants, it was even reduced below the level regarded as the threshold for a depression requiring treatment. Most of the patients experienced those positive stimulation effects within the first week, and they lasted throughout the course of the one-year study.","White matter has a much lower activation threshold than gray matter. Moreover, the heavy anisotropy which surrounds a contact that is located in white matter stops the electric field to expand far away from the electrode. This is the case in our bipolar stimulation, which is performed in slMFB DBS patients (cf.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38803428927&p=1pl&v=1&x=Is_tBXm-qRvqvMT_N0iBZA
10.1038/s41598-018-26952-x,Psychology_easy_558,"In addition to wearing the artificial hand for more time and for more daily tasks when it was sensory enabled, the participants had greater confidence in using the hand to do tasks and to socially interact with loved ones, said Emily Graczyk, a post-doctoral researcher at Case Western Reserve University and lead writer on the new study.",The MDC-90 for the AM-ULA is 3.7 points 27 .,"One said that giving back the sensory device after the study concluded was ""like losing my hand all over again."" In addition to wearing the artificial hand for more time and for more daily tasks when it was sensory enabled, the participants had greater confidence in using the hand to do tasks and to socially interact with loved ones, said Emily Graczyk, a post-doctoral researcher at Case Western Reserve University and lead writer on the new study. These psychological and emotional impacts of sensation could be critical for improving amputees' quality of life, Graczyk said.","In some cases, existing metrics were modified to more specifically apply to this study. The MDC-90 for the AM-ULA is 3.7 points 27 . For subject 2, the AM-ULA was administered in all four testing sessions, but the test in the end of stage 3 session could not be scored because the video data was lost.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=34425102147&p=1pl&v=1&x=uo-e3_BYL2n7L21zoEplJA
10.1007/s13178-010-0017-y,Psychology_easy_559,"Although Dr. Carson apologized, he's still insisting that the basic premise is correct.","These findings are consistent with the conclusion that, apart from being slightly older, the current sample was generally representative of self-identified lesbian, gay, and bisexual adults in the USA.","I regret that my words to express that concept were hurtful and divisive. Although Dr. Carson apologized, he's still insisting that the basic premise is correct. Criminal justice professor Christopher Hensley explained that ""Carson is taking a simplistic view of sexuality.""","6 Except for mean age, the two groups do not differ significantly, as indicated by the overlapping 95% CIs. These findings are consistent with the conclusion that, apart from being slightly older, the current sample was generally representative of self-identified lesbian, gay, and bisexual adults in the USA. Age, Race, Ethnicity, and Education As shown in Table 1, the mean age of respondents was 39,   7 approximately two thirds were non-Hispanic White, and roughly one third had earned a college degree.",[1],Psychology,train,1.0,news,http://www.inquisitr.com/1897396/ben-carson-apologizes-for-prison-homosexuality-comments-still-says-its-a-choice/
10.1038/s41398-017-0063-9,Psychology_easy_560,"Senior author Michael Meaney, who is based at the Douglas Hospital Research Centre, adds, ""It's fascinating to see that interventions that started while a child was in the womb and stopped by age two can leave traces that last a lifetime.",The association between smoking and CAN with AHRR DNA methylation was confirmed using an independent analysis of DNA Table S3 for top ranked CAN-associated vCpGs.,"Though the field of epigenetics is still relatively young and it is difficult for researchers to say exactly what the implications are of these epigenetic modifications, they believe that with further work, this information will prove useful for precision medicine efforts for children and adolescents. Senior author Michael Meaney, who is based at the Douglas Hospital Research Centre, adds, ""It's fascinating to see that interventions that started while a child was in the womb and stopped by age two can leave traces that last a lifetime. This research shows that early intervention programs have an effect.","Thus 75% of participants with a history of CAN were current smokers compared with 41% of pariticipants from the non-abused group (χ 2 = 16.12, p = 5.8E-05). The association between smoking and CAN with AHRR DNA methylation was confirmed using an independent analysis of DNA Table S3 for top ranked CAN-associated vCpGs. The association between CAN and PC1 was reduced to trend level (p = 0.082) but controlling for smoking did not substantively change the association between CAN and PC2 (p = 0.011).",[1],Psychology,train,1.0,news,https://www.futurity.org/nurse-intervention-program-baby-dna-1747202/
10.1080/00224499.2016.1233315,Psychology_easy_561,"Plus, the process can help you form a deeper connection to yourself and learn what kinds of partners and experiences you are (and arenat) willing to spend time and energy on.a

If youare insecure about any of the following things, donat sweat it.","Only the fixed effects varied between the models, with each research question requiring additional effects to be added to the model.","Itas maybe not the sexiest or simplest way to have better sex, but I promise itas the most rewarding. Plus, the process can help you form a deeper connection to yourself and learn what kinds of partners and experiences you are (and arenat) willing to spend time and energy on.a

If youare insecure about any of the following things, donat sweat it. They donat have an impact on how good your sex life is.","It was extended to include SQoL in MIDUS and is based on respondents' own criteria for evaluating the quality of the sexual aspects of their life . Only the fixed effects varied between the models, with each research question requiring additional effects to be added to the model. These results are available in the online supplement.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38005649246&p=1pl&v=1&x=VtgSNj7bXh9LAm-LzeTa4g
10.1098/rspb.2018.1366,Psychology_easy_562,"In response, the critters tucked in their legs and stopped moving.","Finally, because we model the change in network tie formation and boldness change over 19 observations, there are 18 periodspecific rate constants for each of these (inter-)dependent variables.","Just a single bold S. dumicola spider can improve its entire community's hunting skills. In response, the critters tucked in their legs and stopped moving. The bolder the spider, Hunt explained, the quicker it would start to walk again.","Thus, while it is a necessary effect, it is not biologically informative. Finally, because we model the change in network tie formation and boldness change over 19 observations, there are 18 periodspecific rate constants for each of these (inter-)dependent variables. Similar to network density, these constants are not of focal interest [45] .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=35006834701&p=1pl&v=1&x=htbwZQ_2fGyi6PB5JQ94Fg
10.1016/j.physbeh.2006.05.033,Psychology_easy_563,The food police should rethink chastising consumers and turn their attention on the true culprits who are dishing it out.,The results of this study were more consistent with the two studies that found low quinine heritability and differed from the higher levels of heritability noted by .,"Sugar is cheap, and corn syrup even cheaper. However we got here, it's clear that the empty calories are contributing to epidemics of obesity in the U.S. and elsewhere. The food police should rethink chastising consumers and turn their attention on the true culprits who are dishing it out.","However, heritability was low for SOA, quinine, and caffeine, whereas for PROP (chemically similar to PTC), heritability was higher, perhaps because one gene, TAS2R38, can account for much of the variation in this trait. The results of this study were more consistent with the two studies that found low quinine heritability and differed from the higher levels of heritability noted by . Overall, the discrepant levels of heritability noted for quinine may be the result of test unreliability or differences among statistical methods for assessing heritability, in other words, the calculated heritability score may wax or wane dependent upon the method used to compute it.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39678691640&p=1pl&v=1&x=HsVTx2gHwo6nUlEVgRKo8Q
10.1016/j.jagp.2017.10.010,Psychology_easy_564,"""Until there are more high quality randomised controlled trials conducted to confirm the benefits of curcumin or turmeric, it's best to consume turmeric orally as a spice as part of a healthy, nutritious diet,"" Gunveen Kaur, a lecturer in Nutritional Sciences at Deakin University advised.","Ten subjects included in the study did not have baseline and post-treatment PET scans available for analysis because three dropped out before receiving the follow-up scan, three had technical issues with the scans that invalidated the data, and four did not receive scans due to lack of funding.","This means that further studies are still needed to conclude the health benefits of turmeric. ""Until there are more high quality randomised controlled trials conducted to confirm the benefits of curcumin or turmeric, it's best to consume turmeric orally as a spice as part of a healthy, nutritious diet,"" Gunveen Kaur, a lecturer in Nutritional Sciences at Deakin University advised. TAG Turmeric, Curcumin, Spice

c 2018 TECHTIMES.com All rights reserved.","Genetic data were available for 35 of the subjects completing the study. Ten subjects included in the study did not have baseline and post-treatment PET scans available for analysis because three dropped out before receiving the follow-up scan, three had technical issues with the scans that invalidated the data, and four did not receive scans due to lack of funding. A total of 46 subjects who met the study inclusion criteria were randomized; 6 withdrew from participation after randomization (Figure 1 ).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33128955028&p=1pl&v=1&x=KxHbhAmWxfkQ2y82Li2IvA
10.1146/annurev-vision-102016-061207,Psychology_easy_565,"In real life, this fusion of similar elements across space and time during saccades might actually help to prevent confusion, because the continuity helps us to grasp that things we saw before and after a saccade are the same, even if they have moved or if the light has shifted.",2013) .,"The things we see may literally be con-fused--fused together--by our vision, and then more conventionally confused--mistaken for each other--in our minds. In real life, this fusion of similar elements across space and time during saccades might actually help to prevent confusion, because the continuity helps us to grasp that things we saw before and after a saccade are the same, even if they have moved or if the light has shifted. So though the mechanism may seem sloppy, Binda and Morrone believe this sloppiness usually works to our advantage.","• ( Joiner et al. 2013) . In contrast, patients who did not make normal saccades did not use the CD but relied on saccadic errors to make decisions just as did normal monkeys making saccades with errors less than 0.5",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39455729432&p=1pl&v=1&x=YOBf_UJO2Xbr_lMm9X7JDg
10.1016/j.cub.2011.12.018,Psychology_easy_566,"Rather, wolf barks were isolated to just two types: alert and territorial.","Furthermore, dogs followed the actor's gaze significantly less in the BC compared to the O condition [cumulative accuracy, two-sample t test, t(24) = 22.107, p = 0.045].","On the other hand, wolves did not display the same diversity of situational barking. Rather, wolf barks were isolated to just two types: alert and territorial. The ultimate conclusions showed a difference in not only the amount of barking, but also in the types of barking, between domesticated dogs and wolves.","Importantly, however, the accuracy indexes calculated for the cueing phase did not capture gaze following in BC [mean 6 SEM of cumulative accuracy: 20.06 6 0.14; one-sample t test, t(12) = 20.433; p = 0.67; first look: 0.11 6 0.16; one-sample t test, t(12) = 0.695; p = 0.5]. Furthermore, dogs followed the actor's gaze significantly less in the BC compared to the O condition [cumulative accuracy, two-sample t test, t(24) = 22.107, p = 0.045]. These data suggest that the lack of gaze following, when there are no ostensive signals, cannot be accounted for by the confounding effect of ''artificial'' salient attention getter used in the NO condition, also providing further support for the significant role of ostensive signals in dogs' gaze response.",[1],Psychology,train,1.0,news,http://guardianlv.com/2014/05/pets-and-their-owners-can-they-communicate/
10.1177/0164027514527624,Psychology_easy_567,"""Individuals should recognize that making the decision to stop driving is a major life change that needs to be taken seriously,"" said Angela Curl, assistant professor in the School of Social Work within the MU College of Human Environmental Sciences.","Given the relatively small amount of missing data, no imputation was performed.","The researcher recommends that the elderly, and their adult children, carefully discuss and plan for the transition to driving cessation. ""Individuals should recognize that making the decision to stop driving is a major life change that needs to be taken seriously,"" said Angela Curl, assistant professor in the School of Social Work within the MU College of Human Environmental Sciences. ""The safety of the driver should be discussed as just one factor among many.","Five other variables (formal volunteering, self-rated health, cognitive ability, IADL limitations, and driving status) had between 0 and 11 missing observations per wave. Given the relatively small amount of missing data, no imputation was performed. This longitudinal, dyadic study involves repeated measures within couples, and thus data are hierarchical in nature.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/02/150224120920.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29
10.1038/nn.3687,Psychology_easy_568,"The research is primarily intended to understand how memories are formed and retrieved under normal circumstances, but it could be applicable to learning more about people with brain trauma or hippocampal damage due to aging or Alzheimer's.",4a and Supplementary Fig.,"Knierim said the formation and stability of place fields and the newly activated place cells requires further study. The research is primarily intended to understand how memories are formed and retrieved under normal circumstances, but it could be applicable to learning more about people with brain trauma or hippocampal damage due to aging or Alzheimer's. ""There are strong indications that humans and rats share the same spatial mapping functions of the hippocampus, and that these maps are intimately related to how we organize and store our memories of prior life events,"" Knierim said.","7 ) revealed that new fields formed at different times throughout the session, each preceded on the prior lap by a colocalized scan with spiking activity. 4a and Supplementary Fig. 8e,f) .",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2014/04/140414123513.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1037/0033-2909.124.2.262,Psychology_easy_569,"While hiring outside consultants to vet candidates is probably a bit extreme, unless you're hiring some very expensive people, Block has an important point.","The correlation between job tryout ratings and ability scores is estimated at .38 ; that is, it was taken to be the same as that between job sample tests and ability.","Testing for chinks in someone's armor is not only fundamentally different from developing a rapport with someone, it's antithetical. ""One can find outside experts to look for signs of deception, hidden agendas, and potential psychological issues that a candidate might have,"" Block tells Quartz. While hiring outside consultants to vet candidates is probably a bit extreme, unless you're hiring some very expensive people, Block has an important point.","(Range restriction is unlikely with this selection method.) The correlation between job tryout ratings and ability scores is estimated at .38 ; that is, it was taken to be the same as that between job sample tests and ability. Use of the mean correlation between supervisory performance ratings and ability scores yields a similar value (.35, unconnected for measurement error). '",[1],Psychology,train,1.0,news,http://qz.com/336138/the-case-for-ultra-intense-background-checks-for-hires/
10.1016/j.cell.2015.01.003,Psychology_easy_571,"But we no longer have to fear scarcity of certain foods in the wintertime, which means the system is obsolete.","Light-evoked spike latencies, measured from light-pulse onset to the peak of the action potential, ranged from 3-8 ms ( Figure 1C ).","Whenever valuable nutritious food sources were scarce or unavailable, the brain would desire sugar to fulfill an instinctual survival need. But we no longer have to fear scarcity of certain foods in the wintertime, which means the system is obsolete. The discovery of a specific neural circuit underlying compulsive sugar consumption could pave the way for the development of targeted drug therapies to effectively treat this widespread problem.""","Subsequent recombination permitted opsin and fluorophore expression selectively in LH neurons providing monosynaptic input to the VTA. Light-evoked spike latencies, measured from light-pulse onset to the peak of the action potential, ranged from 3-8 ms ( Figure 1C ). We also found that none of the non-expressing (ChR2-negative) cells recorded showed excitatory responses to photostimulation (n = 14; Figure 1C ), despite their proximity to ChR2-expressing cells.",[1],Psychology,train,1.0,news,http://www.medicaldaily.com/how-stop-binge-eating-brain-circuit-controls-compulsive-overeating-and-sugar-319972
10.1038/s41598-018-31129-7,Psychology_easy_572,"if you can see a beach, ocean sky, rocks and stars then you are an artist, But its not a painting its lower part of the car gate which needs to be repaired.",Initial checks of task compliance (see methods for details) revealed that a significant proportion of participants (55%) from India were not able to complete the task.,"if you can see a beach, ocean sky, rocks and stars then you are an artist, But its not a painting its lower part of the car gate which needs to be repaired. It relates to the way the brain and eyes work together to see an image--when looking at a 2D image, the brain can be tricked because it does not have all the information it needs to make sense of what is there, such as depth, lighting and position. Brain scans showed that people process the illusion in the same way as they would a moving object, and that there was a processing gap of 15 milliseconds by neurons in the area of the brain that is critical for picking up visual motion.",It is therefore expected that the range of reported ages will be larger for older compared to younger respondents. Initial checks of task compliance (see methods for details) revealed that a significant proportion of participants (55%) from India were not able to complete the task. The advantage of this sample is that it is relatively homogenous and also that Americans generally have more negative views toward ageing compared to Indians -especially in relation to socio-emotional processes .,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39649765711&p=1pl&v=1&x=ggFidRrecBpB_aLp7rO8MQ
10.1177/0146167216666265,Psychology_easy_573,"But if, as they say in this electoral season, you're looking to ""grow your base,"" exercising emotional intelligence - expressing empathy, checking your emotions in a bid to avoid conflict, and investing in personal relationships - is a strategy that beats narcissism over the long term.",No other significant differences were noted.,"But if, as they say in this electoral season, you're looking to ""grow your base,"" exercising emotional intelligence - expressing empathy, checking your emotions in a bid to avoid conflict, and investing in personal relationships - is a strategy that beats narcissism over the long term. The findings: When a group of strangers is thrown together, individuals who score high on narcissism enjoy an early surge of admiration, recognition and friendship among their peers. But over time, their self-assurance and showmanship cease to build or sustain the growth of friendships.","This group had significantly lower probability of being nominated as a friend than any other group (all ps<.003), across time. No other significant differences were noted. These effects were not significantly different between the two measurement points, as indicated by insignificant three-way interaction of narcissism, EI and time.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/narcissists-may-start-out-popular-but-people-see-through-them-in-the-long-run/
10.1111/jcpp.12665,Psychology_easy_574,Co-parenting still exists in this family dynamics in the technical sense.,"The direction of the interaction we illuminated was striking, and not anticipated.",Mothers usually feel that they are good parents if partners support each other and have shared values or a similar direction on how they should raise their children. Co-parenting still exists in this family dynamics in the technical sense. Don't spew angry harsh words to control your child.,"We discuss our results, before noting study limitations and future directions. The direction of the interaction we illuminated was striking, and not anticipated. Instead, we found that mothers' perceptions of high quality coparenting exacerbated the association between her coercive parenting and the development of disruptive behaviour.",[1],Psychology,train,1.0,news,http://www.parentherald.com/articles/95184/20161222/co-parenting-using-harsh-strategies-wont-correct-childs-bad-behavior.htm
10.1016/j.neuron.2015.06.031,Psychology_easy_575,The more cynical among us may believe altruists are suckers and nothing more.,The observed data displayed both patterns.,Maybe we help strangers out of fear of reprisals for inaction. The more cynical among us may believe altruists are suckers and nothing more. Perhaps we choose to be altruistic in much the same way we choose between different vacation spots or brands of peanut butter.,"Second, it predicts that this RT difference is bigger for more selfish subjects (correlation between predicted generosity and difference in G versus S RTs r 49 = À0.89, p < 0.0001; Figure 4B ). The observed data displayed both patterns. On average, G choices were significantly slower than S choices (RT G = 2,300 ms ± 310, RT S = 2,131 ms ± 280, paired t 43 = 4.97, p < 0.0001; Figure 4C ), and the more generous the individual, the smaller this difference (r 42 = À0.60, p < 0.001, Figure 4D ).",[1],Psychology,train,1.0,news,http://www.psmag.com/health-and-behavior/choosing-altruism
10.1073/pnas.1524982113,Psychology_easy_576,"""And that would be really exciting.""","Participants with larger accuracy differences between the hardest and easiest math conditions also showed a larger activation difference between these conditions in number-responsive visual cortex (rMOG) (R 2 = 0.28, P = 0.03; Fig.","The result suggests the brain can rewire visual cortex to do just about anything, Bedny says. And if that's true, she says, it could lead to new treatments for people who've had a stroke or other injury that has damaged one part of the brain. ""And that would be really exciting.""","In the blind group, visual cortex activity correlated with performance on the math task. Participants with larger accuracy differences between the hardest and easiest math conditions also showed a larger activation difference between these conditions in number-responsive visual cortex (rMOG) (R 2 = 0.28, P = 0.03; Fig. This correlation was not significant in the sighted participants (R 2 = 0.06, P = 0.33; Fig.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/when-blind-people-do-algebra-the-brains-visual-areas-light-up/
10.1002/aur.1799,Psychology_easy_577,"Ozone on its own had very little effect on risk for autism, such that in studies that did not take interactions among risk factors into consideration, it may have been ignored.","Regions are large, generally encompassing multiple counties, and correspond to the catchment areas of Regional Centers that coordinate services of the California DDS.","However, when the researchers evaluated interactions among the various risk factors they saw a large effect of ozone among children with either duplications or total copy-number variation. Ozone on its own had very little effect on risk for autism, such that in studies that did not take interactions among risk factors into consideration, it may have been ignored. Interactions among the various other factors, even those with large individual effects, appeared to have very little effect on risk.","The paucity of gene-environment interaction measures has a simple origin, it requires detailed genetic and environmental data for the same group of individuals, an expensive and time consuming endeavor. Regions are large, generally encompassing multiple counties, and correspond to the catchment areas of Regional Centers that coordinate services of the California DDS. This sampling strategy ensures that confounding related to regional characteristics is minimized, and simultaneously that the cases and controls are not over-matched with regard to geographically-related exposures.",[1],Psychology,train,1.0,news,http://www.futurity.org/environment-and-genetics-autism-1470592/
10.1093/geronb/gbx092,Psychology_easy_578,"Oh, and donat forget to take lots of pics a you never know if youall spot something with IG potential.","Despite these limitations, the results from this study provide encouraging support for the potential of volunteer engagement as an intervention for alleviating loneliness among widows.","Chelsea Victoria/Stocksy TBH, thereas hardly a better way to get into the holiday spirit than to gawk at the mind-blowing decorations your neighbors have set up around their houses. Oh, and donat forget to take lots of pics a you never know if youall spot something with IG potential. Jamie Grill Atlas/Stocksy If youare looking for a way to take your mind off being single this holiday season, consider volunteering.","Although the goals of this study focus on whether starting a new volunteering role relates to lower levels of loneliness following widowhood regardless of previous volunteer history, future research might examine transitions into and out of volunteer work, its co-occurrence with caregiving and its effect on loneliness to determine if these effects vary based on history of volunteer engagement. Despite these limitations, the results from this study provide encouraging support for the potential of volunteer engagement as an intervention for alleviating loneliness among widows. In addition, given the numerous benefits associated with engaging in volunteering in general, and with 2 hr or more per week in particular , individuals who start a new volunteer role and continue to remain engaged over an extended period may experience health and well-being benefits that facilitate more successful aging.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38008140585&p=1pl&v=1&x=qnKpareG_EywYlUgp_w29A
10.1177/0956797613504221,Psychology_easy_579,"For example, airport screeners are more likely to encounter pocket knives or incorrectly-packed prescription medications than they are to see a gun in a carry-on bag.","R 2 s = .50 and .66, respectively), but the logarithmic function provided the best fit.","""This effect is about being able to detect specific items and how likely you are to miss them when they occur infrequently."" For example, airport screeners are more likely to encounter pocket knives or incorrectly-packed prescription medications than they are to see a gun in a carry-on bag. So, they might become conditioned to catch the illegal, though relatively harmless, items that appear more frequently than a rarely-seen weapon.","The data were also significantly explained by linear and quadratic functions (Adj. R 2 s = .50 and .66, respectively), but the logarithmic function provided the best fit. The 30 targets with a frequency rate below 0.15% were detected only 27% of the time, whereas the 23 targets with rates above 1% were detected on 92% of the trials.",[1],Psychology,train,1.0,news,http://www.homelandsecuritynewswire.com/dr20131209-airport-screeners-miss-unusual-and-possibly-dangerous-items
10.1038/s41598-018-30721-1,Psychology_easy_580,"She calls dreams ""our built-in helpers,"" and says there is no reason to be afraid of a dream, even if it's causing you anxiety.",Good reliability of the Swedish version of the scale has also been demonstrated (α = 0.87) 98 .,"""What is literal in a dream though is the emotion you experience because the emotion in the dream is connected to that same emotion you are having about something in your real life. She calls dreams ""our built-in helpers,"" and says there is no reason to be afraid of a dream, even if it's causing you anxiety. LightField Studios / Shutterstock

If you're not sure where to start, there are things you can do before going to sleep to reduce your chances of riding the anxiety dream wave through the night and into the next day.",The scale has been shown to be unidimensional and display good psychometric properties (α ranging from 0.87 to 0.89) 97 . Good reliability of the Swedish version of the scale has also been demonstrated (α = 0.87) 98 . 17 demonstrated it to be a valid and reliable measure also in a Western sample (European Americans).,[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39590248166&p=1pl&v=1&x=hhGmCwi_rumWG_pcy1pWwA
10.1007/s10803-017-3415-7,Psychology_easy_581,"Once we understand that and what it means for our child, there is the potential for everything gets easier.","All teams added new referrals to the database, with the exception of team 2 and therefore the 2016 total recorded referral rate continues to be an underestimate.","Please remember that autism is different for everyone. Once we understand that and what it means for our child, there is the potential for everything gets easier. View photos She may have a very sensitive head.","As well as being consistent with evidence based clinical guidelines, key features and new consensus included: a single pathway; a single way of recording referrals; a triage process; use of the abbreviated/complex pathway; consensus on contextual assessment guidance; report writing guidance and information leaflets about the pathway for staff and families. All teams added new referrals to the database, with the exception of team 2 and therefore the 2016 total recorded referral rate continues to be an underestimate. Although previous evaluation highlighted the inaccuracy of estimation, this service estimated by counting the number of ADOS assessments completed in 2016 and estimated around 100 cases were not on the database.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39940643099&p=1pl&v=1&x=n57wkNPFDoXNhqkd83frfA
10.1038/s41398-018-0319-z,Psychology_easy_582,"Identifying the downstream effects of the mutation could help identify new treatment targets for frontotemporal dementia, Alzheimer's disease and other tau-related illnesses, including Parkinson's disease.",5a ; P-value < 0.0001).,"The new findings zero in on the MAPT gene. Identifying the downstream effects of the mutation could help identify new treatment targets for frontotemporal dementia, Alzheimer's disease and other tau-related illnesses, including Parkinson's disease. The study is published Dec. 13 in the journal Translational Psychiatry.","The 61 genes were significantly enriched for FTD risk variants ( Fig. 5a ; P-value < 0.0001). Furthermore, we demonstrate that the SNPs within the 61 differentially expressed genes are more significantly associated with FTD risk than expected by chance (Fig.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37984371439&p=1pl&v=1&x=PEQ4740-gkHLNp2Z68gIQw
10.1038/mp.2017.184,Psychology_easy_583,Abel notes that funding from the Simons Foundation was critical to the success of the project.,"ERK1 protein levels reached approximately 75% of female WT levels, appreciably higher than the 50% of male WT ERK1 protein seen in male del/+ striatum (Figure 4) .","One emerging theme, supported by the new study, is that a deficit in reward learning may be a common feature of ASD, and males are specifically deficient in this type of behavior. Abel notes that funding from the Simons Foundation was critical to the success of the project. The impact they have had on autism research has been tremendous,"" he says.","Unexpectedly, female del/+ had higher ERK1 and ERK2 protein levels than would be expected by gene expression levels alone. ERK1 protein levels reached approximately 75% of female WT levels, appreciably higher than the 50% of male WT ERK1 protein seen in male del/+ striatum (Figure 4) . Likewise, total ERK2 protein levels were significantly elevated in del/+ females compared with WT females, despite similar levels of ERK2 mRNA expression in these groups (Supplementary Figure 8) .",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/signaling-pathway-may-be-key-to-why-autism-is-more-common-in-boys/
10.1073/pnas.1816581115,Psychology_easy_584,"[Arvid Guterstam et al., Implicit model of other people's visual attention as an invisible, force-carrying beam projecting from the eyes]

Vision depends on light entering the eye...a form of ocular intromission, if you will.","Participants showed a significant bias that, in our interpretation, indicates an implicit belief in an invisible force that emanates from the eyes and mechanically pushes on objects.","That eye-opening finding appears in the Proceedings of the National Academy of Sciences. [Arvid Guterstam et al., Implicit model of other people's visual attention as an invisible, force-carrying beam projecting from the eyes]

Vision depends on light entering the eye...a form of ocular intromission, if you will. What the researchers found is that, when there was someone staring at the tube, subjects thought that the tube could tilt a little further before it toppled toward the fella looking at it.","It may depend on automatic, implicit models about gaze that are robust against intellectual knowledge . Participants showed a significant bias that, in our interpretation, indicates an implicit belief in an invisible force that emanates from the eyes and mechanically pushes on objects. The implied force was small in magnitude, corresponding to about a hundredth of a newton, comparable to a light puff of air.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38062613050&p=1pl&v=1&x=B5CzlFuHpt56dvr9NfaMxw
10.1093/brain/awh577,Psychology_easy_585,And this brings us back to issue of control.,"The success score of the medial group was not significantly different from that of controls both on type A and on type C problems (Fisher's exact test, P > 0.1).","Easy, it doesn't feel like we're doing anything to solve the problem. And this brings us back to issue of control. If you're the kind of person who wants to control a situation then the guilt of not doing anything is overwhelming.","Within the lateral group, A and C success scores were not significantly different from each other (McNemar test, P > 0.1). The success score of the medial group was not significantly different from that of controls both on type A and on type C problems (Fisher's exact test, P > 0.1). Within the medial group, A and C success scores were not significantly different from each other (McNemar test, P > 0.1).",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=40038772733&p=1pl&v=1&x=lZKnpZ-69CrMvH8l8HUxzg
10.1073/pnas.1703920114,Psychology_easy_586,"""We gave the intranasal vesicle spray twice over 24 hours, the first one at two hours after the onset of a status epilepticus episode, and such treatment was effective at reducing multiple adverse effects on the hippocampus,"" says Ashok K. Shetty, professor of molecular and cellular medicine and co-senior author of the paper.","Interneurons expressing SS exhibited reduced densities in the DH+GCL, CA1, and CA3 regions after SE (Fig.","It was able to ease inflammation of the neurons, prevent cognitive and memory dysfunction, and stop abnormal neurogenesis in the hippocampus, a vital part of the brain responsible for memory. ""We gave the intranasal vesicle spray twice over 24 hours, the first one at two hours after the onset of a status epilepticus episode, and such treatment was effective at reducing multiple adverse effects on the hippocampus,"" says Ashok K. Shetty, professor of molecular and cellular medicine and co-senior author of the paper. ""In fact, the vesicles were able to move to the hippocampus in six hours, and their neuroprotection was enough to prevent loss of normal cognitive and memory function as well as abnormal neurogenesis, one of the substrates involved in formation of new memories.""","Because of the protection mediated by A1-exosomes, the SE-EVs group displayed 34-69% greater numbers of PV + interneurons than the SE-VEH group (P < 0.05; Fig. Interneurons expressing SS exhibited reduced densities in the DH+GCL, CA1, and CA3 regions after SE (Fig. 5 A1-C3 ).",[1],Psychology,train,1.0,news,http://www.futurity.org/seizures-nasal-spray-1399492-2/
10.1007/s11682-010-9099-7,Psychology_easy_587,"For me, that would mean managing time and getting around without a map more efficiently.",Results from these simulations indicated that only activation clusters thresholded at α≤0.001 with a volume greater than 496 μl would have global significance at p≤0.05 for the cortical data smoothed with an 8 mm filter.,"These exercises may help declutter my overworked brain, so that the whole system functions more smoothly. For me, that would mean managing time and getting around without a map more efficiently. That said, he had mentioned nothing about goggles.",This method allows for a combination of thresholding and spatial clustering to produce a corrected p-value. Results from these simulations indicated that only activation clusters thresholded at α≤0.001 with a volume greater than 496 μl would have global significance at p≤0.05 for the cortical data smoothed with an 8 mm filter. Only clusters with volumes greater than these cutoffs are displayed in the figures and tables.,[1],Psychology,train,1.0,news,http://www.theatlantic.com/health/archive/2015/06/compensating-for-the-missing-chunk-of-my-brain/395342/
10.1177/0956797614535810,Psychology_easy_588,They say that those nuances don't change the results.,"Domain was a statistically significant moderator, Q(4) = 49.09, p < .001.","Some say that the authors didn't define practice clearly enough, lumping in casual play with serious lessons and thus diluting true practice's effect. The authors of the new paper, however, are sticking to their findings. They say that those nuances don't change the results.","Similarly, for studies with multiple performance measures, the result for each measure (M1, M2, etc.) Domain was a statistically significant moderator, Q(4) = 49.09, p < .001. Percentage of variance in performance explained by deliberate practice was 26% for games ( = .51, p < .001), 21% for music ( = .46, p < .001), 18% for sports ( = .42, p < .001), 4% for education ( = .21, p < .001), and less than 1% for professions ( = .05, p = .62; see Fig.",[1],Psychology,train,1.0,news,http://www.smithsonianmag.com/smart-news/some-experts-think-no-matter-how-much-you-practice-if-you-dont-have-natural-talent-youll-probably-never-be-best-180952045/
10.1038/s41598-019-40468-y,Psychology_easy_589,"Bisherige Annahmen gingen davon aus, dass sich die Fahigkeit zu Toleranz und Kooperation bei Hunden hauptsachlich im Lauf der Domestizierung ihrer wilden Vorfahren entwickelt hat.",This latter suggestion is further supported by the fact that highly trained pet dogs do cooperate with each other at least in their owner's presence that may mediate tolerance between the dogs .,"(c) Bereitgestellt von Styria Digital One GmbH

Wann aus Wolfen Hunde wurden, ist bis heute nicht genau datiert, vermutlich geschah es irgendwann vor 20.000 bis 40.000 Jahren. Bisherige Annahmen gingen davon aus, dass sich die Fahigkeit zu Toleranz und Kooperation bei Hunden hauptsachlich im Lauf der Domestizierung ihrer wilden Vorfahren entwickelt hat. erschienen ist, zeigt jedoch, dass sich die Wolfe dafur keine neuen Merkmale aneignen mussen und daher vermutlich auch in der fruhen Sozialisation mit dem Menschen die Zusammenarbeit so gut funktioniert hat wie bei heutigen Hunden.","Interestingly though, in this task, our dogs performed rather poorly, which could be due to a reduction either in their cognitive understanding of different components of the task or in their tolerance towards conspecifics preventing dogs from working simultaneously at the apparatus . This latter suggestion is further supported by the fact that highly trained pet dogs do cooperate with each other at least in their owner's presence that may mediate tolerance between the dogs . These previous results raise a few additional questions regarding wolves' and dogs' cooperative abilities.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38775294660&p=1pl&v=1&x=icC-_BuPPPfeIgXjq4T_uw
10.1186/1747-5341-4-2,Psychology_easy_590,But the research does create a precedent that shows a need for further investigation into the effects of anaesthesia on the developing human foetus.,"No reasonable person who understands evolutionary biology, and who knows, for example, that rodents and humans have taken very different evolutionary trajectories since the lineages leading to modern humans and rodents, respectively, diverged over seventy million years ago, will expect qualitative identity.","Although there is a clear association in rats, that doesn't necessarily mean the effect is exactly the same in humans, since animal models are not always predictive for human responses. But the research does create a precedent that shows a need for further investigation into the effects of anaesthesia on the developing human foetus. It also indicates that perhaps care should be taken when choosing the best time for a pregnant woman to undergo surgery.","In a way, the whole issue of prediction comes down to the principle of uniformity. No reasonable person who understands evolutionary biology, and who knows, for example, that rodents and humans have taken very different evolutionary trajectories since the lineages leading to modern humans and rodents, respectively, diverged over seventy million years ago, will expect qualitative identity. But perhaps qualitative identity is an ideal that can only be approximated.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38992445023&p=1pl&v=1&x=-LogYGNx8CesBVVdGB1AjQ
10.1001/jamapsychiatry.2013.203,Psychology_easy_591,We could envisage using a marker like this one to identify people who are least likely to respond to existing medications and focus our efforts on developing new medication specifically adapted to this group.,"Unlike the curvaturebased methods used in some studies, 74 the method by Schaer and colleagues that we used provides a composite index that captures both the curvature or depth and the spatial fre-quency or density of sulcogyral patterns on the cortical surface.","It is possible that the alterations we observed are due to differences in the way the brain has developed early on in people who do not respond to medication compared to those who do."" We could envisage using a marker like this one to identify people who are least likely to respond to existing medications and focus our efforts on developing new medication specifically adapted to this group. In the longer term, if we were able to identify poor responders at the outset, we may be able to formulate personalized treatment plans for that individual patient.""","Our study has a number of strengths. Unlike the curvaturebased methods used in some studies, 74 the method by Schaer and colleagues that we used provides a composite index that captures both the curvature or depth and the spatial fre-quency or density of sulcogyral patterns on the cortical surface. Hence, the hypogyric regions we observed could reflect either a reduced number of sulcal formations or an increased width and reduced depth of the sulci themselves.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/08/130814191924.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1016/j.neuron.2017.04.037,Psychology_easy_592,"I think what researchers are saying is this: The next time someone gets on your case about how you lost your keys again, you can simply tell them that you're smarter than them.","The same manipulations bidirectionally modulated the stability of LTP, measured in CA3.","It might actually be healthier to forget certain memories, so that your brain can have the bigger picture and make more informed decisions. I think what researchers are saying is this: The next time someone gets on your case about how you lost your keys again, you can simply tell them that you're smarter than them. Regardless, regularly misplacing everyday items that you can't do without is a major pain a particularly when you're already late for work and you can't find your car keys, which you later discover somehow ended up in the refrigerator.","In contrast, hippocampal overexpression of a constitutively active form of Rac1 accelerated decay, with performance falling to chance levels within 24 hr of training (see also Jiang et al., 2016 for similar results using pharmacological inhibition of Rac1). The same manipulations bidirectionally modulated the stability of LTP, measured in CA3. Decreasing Rac1 activity prevented LTP decay, whereas increasing Rac1 activity accelerated loss of LTP .",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38927029810&p=1pl&v=1&x=w-mJ1wKc8xhjtJZilyICHw
10.1073/pnas.1813588116,Psychology_easy_594,"""It's a serious deficit we're all feeling,"" Baime said.","Although this study carefully controlled for nonspecific intervention factors, acceptance training may build on several of these contextual features.","The finding could be a step toward mitigating a nationwide problem of loneliness. ""It's a serious deficit we're all feeling,"" Baime said. While one study is not enough to prove smartphone-led meditation is the solution, it's a promising start, he said.","In hopes of guiding further research that builds on the present findings, we highlight several considerations about the study design and interventions that may prove important for replication and extension. Although this study carefully controlled for nonspecific intervention factors, acceptance training may build on several of these contextual features. First, it is important to reiterate that monitoring and acceptance-rather than acceptance alone-act synergistically to reduce social risk factors.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38900367506&p=1pl&v=1&x=1dIqfbvAJgVzkVngEc3ZNw
10.1093/cercor/bhv043,Psychology_easy_595,A momentary lapse of concentration is all it takes for a finger to become trapped or sprain an ankle -- and it hurts.,"The upper row of Figure 2A shows the topographies of this relationship for theta (4-7 Hz), alpha (8-13 Hz), beta (14-29 Hz), and gamma (30-100 Hz) frequencies.","A momentary lapse of concentration is all it takes for a finger to become trapped or sprain an ankle -- and it hurts. This method makes it possible to chronologically pinpoint which signals nerve cells use to respond to a pain stimulus. ""We were absolutely amazed by the results: After just a few minutes, the subjective perception of pain changed -- for example, the subjects felt changes in pain when the objective stimulus remained unchanged.","This analysis yielded a statistical estimate of the strength of the relationship between brain activity and subjective pain intensity for each electrode and frequency band. The upper row of Figure 2A shows the topographies of this relationship for theta (4-7 Hz), alpha (8-13 Hz), beta (14-29 Hz), and gamma (30-100 Hz) frequencies. The results show that neuronal gamma oscillations at frontal electrodes encoded the subjective intensity of tonic pain (t max = 4.1 at electrode F3).",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2015/03/150311124530.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29
10.1093/geronb/gbs112,Psychology_easy_596,This can be done by focusing on getting people to intensify their engagement in a variety of cognitive activities even if they have lower levels of motivation to do so.,This interpretation is speculative but testable.,"Says Baer, ""it is my hope that these results will influence the design of future interventions aimed at maintaining the cognitive health of retirees. This can be done by focusing on getting people to intensify their engagement in a variety of cognitive activities even if they have lower levels of motivation to do so. It is equally important to address symptoms of depression to help fight against cognitive decline.""","As discussed earlier, need for cognition might motivate individuals to seek further intellectual challenge within their chosen set of activities. This interpretation is speculative but testable. A future study should include a more detailed assessment of cognitive activity that includes indices of the variety and novelty of activities engaged in, as well as the level of engagement for each activity using ratings of challenge, effort, and duration as suggested previously.",[1],Psychology,train,1.0,news,http://www.sciencedaily.com/releases/2013/10/131001115650.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28ScienceDaily%3A+Latest+Science+News%29
10.1038/s41586-018-0647-4,Psychology_easy_597,And the same goes when you are an advocate trying to convince others to do the right thing.,4) .,"""If you are a salesman trying to sell something, you better be using it. And the same goes when you are an advocate trying to convince others to do the right thing. Furthermore, they show why actions matter so much: your actions help to reveal what you actually think, as opposed to just what you claim to think.","A random-effects meta-analysis on the four effect sizes reveals a significant positive effect of the ambassador engaging in the behaviour (d = 0.33, 95% CI = 0.21-0.44, Z = 5.63, P < 0.001), and no evidence of heterogeneity in effect size across behaviours (χ 3 2 = 2.37, P = 0.499) (Fig. 4) . Finally, aggregating over the four behaviours we find that the second-order-belief scale (α = 0.91) significantly and fully mediates the effect of ambassador engagement (89% of the effect) (see Methods, Supplementary Information section 5 and Extended Data Fig.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=37486425952&p=1pl&v=1&x=xOiV9Jb5-gg3bOodKC9V5g
10.1073/pnas.1704547114,Psychology_easy_598,"They could reverse the behavior by reintroducing histamine directly into the striatum, confirming that this structure is a central contributor to the pathology.","(E) Striatal c-fos was also up-regulated in the dStr after CNO treatment: t(11) = 4.79; P = 0.0006; n = 7 saline, 6 CNO.","""It is easier to imagine how this insight might develop into a treatment than if the abnormalities arose during early development."" The researchers were able to trigger excessive grooming in mice by shutting down histamine neurons projecting to the basal ganglia, an area of the brain previously linked to Tourette. They could reverse the behavior by reintroducing histamine directly into the striatum, confirming that this structure is a central contributor to the pathology.","A similar effect was seen in a larger open-field environment: chemogenetic inhibition of Mann-Whitney U = 12; P = 0.0375; n = 8 per group. (E) Striatal c-fos was also up-regulated in the dStr after CNO treatment: t(11) = 4.79; P = 0.0006; n = 7 saline, 6 CNO. (F) Because c-fos gave the cleaner result in the dStr analysis we selected it for counting in the mPFC.",[1],Psychology,train,1.0,news,http://feedproxy.google.com/~r/TechnologyOrg/~3/FuGXHb_Ue4M/
10.1073/pnas.0705435104,Psychology_easy_602,"Which is all to say that Baebraham Lincoln, the apple of social media's eye, shirtless in the Los Angeles courthouse, may very well be following an artistic tradition, born out of a pseudoscience, to make our political leaders' looks match their moral virtue.","The test for dependence of judgments and incumbency status was not significant [ 2 (2) ϭ 1.95, P ϭ 0.38] (see Table 2 for the relevant proportions).","In this case, ""vigorous"" can be translated to mean swashbuckling and 28. Which is all to say that Baebraham Lincoln, the apple of social media's eye, shirtless in the Los Angeles courthouse, may very well be following an artistic tradition, born out of a pseudoscience, to make our political leaders' looks match their moral virtue. Or, you never know, maybe it's as simple as what Hansen suggested: the president just looked better sans shirt and jacked.","Competence judgments were independent of incumbency status in predicting the outcome of the elections. The test for dependence of judgments and incumbency status was not significant [ 2 (2) ϭ 1.95, P ϭ 0.38] (see Table 2 for the relevant proportions). Collapsing across the races in which the incumbent lost and the races with no incumbent, the candidate who was perceived as more competent won in 62.7% of the races.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=38689048949&p=1pl&v=1&x=NKR-qKpy562iVJIMO7OSlA
10.1177/0956797615575277,Psychology_easy_603,"For more information about this study, please contact: Maryam Kouchaki at m-kouchaki@kellogg.northwestern.edu.","The remaining three word segments (F_ O _, B_ _ K, and PA_ _ R) could be completed with neutral words only.","The complete Open Practices Disclosure for this article can be found at http://pss.sagepub.com/content/by/supplemental-data. More information about the Open Practices badges can be found at https://osf.io/tvyxz/wiki/view/ and http://pss.sagepub.com/content/25/1/3.full. For more information about this study, please contact: Maryam Kouchaki at m-kouchaki@kellogg.northwestern.edu.","Three of the word segments (W_ _H, SH_ _ER, and S_ _P) could be completed as cleansing-related words (wash, shower, and soap) or as unrelated, neutral words (e.g., wish, shaker, and step). The remaining three word segments (F_ O _, B_ _ K, and PA_ _ R) could be completed with neutral words only. We averaged responses to the five cleansing products to create one aggregate measure (α = .86).",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/hiding-your-true-colors-may-make-you-feel-morally-tainted/
10.1177/070674370705200508,Psychology_easy_604,"The MoCa is easy to ridicule, as many on the left are doing.",La sensibilité et la spécificité des deux mesures ont été évaluées pour la détection du TCL et de la démence.,"It's also not the only, or necessarily best, way to assess cognitive decline. The MoCa is easy to ridicule, as many on the left are doing. It's also odd to boast about (see Donald Trump Jr's tweet below.)","Les diagnostics cliniques de démence et de TCL ont été posés d'après les critères du CIM-10 et de Petersen. La sensibilité et la spécificité des deux mesures ont été évaluées pour la détection du TCL et de la démence. Résultats : Avec un score d'inclusion de 26, le MMSE avait une sensibilité de 17 % pour détecter les sujets souffrant de TCL, alors que la MoCA en détectait 83 %.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=33026711117&p=1pl&v=1&x=1Dn7Pu85IK6Yr30w5c7b6A
10.1177/0022022117698039,Psychology_easy_605,"Having this unconscious sense of the space around the body helps us feel safe, says Graziano.",Details on the applied method can be found in Supplementary File 1.,"It also helps us navigate social interactions, such as knowing where to stand with respect to other people at a party. Having this unconscious sense of the space around the body helps us feel safe, says Graziano. And it turns out we crave that margin of safety for others too--in fact, those ""bubble wrap"" brain neurons also fire when we see someone else's personal space invaded, he says: ""You cringe because you're simulating what it would be like if it was happening to you--and all the same brain mechanisms are activated.""","If the effect of temperature on personal distance preferences is direct, closer interpersonal distances should be observed in cultures of higher annual average temperature. Details on the applied method can be found in Supplementary File 1. Significant difference is suggested when the confidence intervals of two countries do not overlap.",[1],Psychology,train,1.0,news,http://ct.moreover.com/?a=39970084391&p=1pl&v=1&x=Baapm8TsHD4FW050Sok7jQ
10.1001/jamapsychiatry.2014.3008,Psychology_easy_608,"Though only proof-of-principle, Courchesne said the findings are encouraging.","From this process, 4 of 12 modules were identified (M1 is blue, M2 is black, M3 is purple, and M4 is green yellow in eFigure 1 in Supplement 1) that displayed the best area under the curve performance.","Our current work is aimed at recruiting sufficiently large samples of females to begin work to discover possible gene expression markers for them.aEUR

Courchesne emphasized that this was a first step toward a possible means of diagnosing autism much earlier than current methodologies, one that would greatly boost the efficacy of intervention and remedial treatments. Though only proof-of-principle, Courchesne said the findings are encouraging. Next steps involve further refinement of the process and identification of diagnostic risk markers for females.","The significant threshold of univariate tests was .05 (Supplement 2). From this process, 4 of 12 modules were identified (M1 is blue, M2 is black, M3 is purple, and M4 is green yellow in eFigure 1 in Supplement 1) that displayed the best area under the curve performance. Because of the differences in microarray platforms, only 2070 of 2765 discovery DE genes (75%) were present in the replication data set, and only 678 of 762 four-module classifier genes (89%) were actually represented by replication MEs and used in the classification test of the replication participants.",[1],Psychology,train,1.0,news,http://healthmedicinet.com/news/blood-based-genetic-biomarkers-identify-young-boys-with-autism/