press_release_conclusion: “Our results show that reducing the amount of growth factor that’s available around the intraocular lens significantly impedes cell invasion and adds to the evidence in favour of open-bag cataract surgery,” continues Dr Wormstone. “Moreover, we found that vascular endothelial growth factor (VEGF) plays an important role in cell growth and survival. Therefore we believe that anti-VEGF treatment is a logical target for new drug treatments that could help enhance the effect of better lens design and placement, to prevent secondary cataract.”
abstract_conclusion: In particular, VEGF was found to regulate cell survival, growth and myofibroblast formation.