press_release_conclusion: A cell therapy that could prevent transplanted organs being rejected, and remove the need for prolonged use of immunosuppressant drugs, has shown promise in early-stage studies in mice.
abstract_conclusion: Without further manipulation or selection, the resultant population delayed skin allograft rejection mediated by polyclonal CD4(+) effectors or donor-reactive CD8(+) T cell receptor transgenic T cells and inhibited both effector cell proliferation and T cell priming for interferon-γ production.