context1: Patients that experience frequent attacks can develop chronic neuropathic pain in extremities as well as chronic pain in the <strong>gut</strong>. This is thought to be due to axonal <strong>nerve</strong> deterioration in affected areas of the nervous system. In these cases, treatment with long-acting opioids may be indicated.
context2: Cheilostome colonies are composed of calcium carbonate and grow on a variety of surfaces, including rocks, shells, seagrass and kelps. The colony shapes range from simple encrusting sheets to erect branching and even unattached forms. As in other bryozoan groups, each colony is composed of a few to thousands of individual polypides, which has a U-shaped <strong>gut</strong>, and no respiratory, circulatory, or <strong>nerve</strong> system.