evidence: In both OCTAVE Induction 1 and 2, treatment with tofacitinib 10 mg BID resulted in statistically significant improvements from baseline in mean IBDQ total score versus placebo at Week 4 and Week 8 [p < 0.0001 for all comparisons;
intervention: Tofacitinib 10 mg
comparator: Placebo
outcome: Remission 