evidence: Following oral methionine the tHcy concentration at 4 hours increased significantly (7.5 [6.0-9.0] μmol/L vs. 22.8 [19.8-25.8] μmol/L, p < 0.0001 vs. baseline and Placebo, Table 1).
intervention: methionine (100 mg/Kg) plus placebo tablets
comparator: placebo drink plus placebo tablets
outcome: Homocysteine (tHcy) concentration