evidence: The relative contributions of breathlessness [0.9% saline, 41.9 ± 3.4%; 40 mg furosemide, 40.2 ± 3.6%; 120 mg furosemide, 39.4 ± 4.0% (p = 0.876)], leg discomfort [0.9% saline, 55.4 ± 4.1%; 40 mg furosemide, 54.4 ± 4.2%; 120 mg furosemide, 51.7 ± 4.6% (p = 0.746)] and chest tightness [0.9% saline, 2.4 ± 1.5%; 40 mg furosemide, 0.8 ± 0.8%; 120 mg furosemide, 6.0 ± 3.3% (p = 0.170)] to exercise cessation were not significantly different across treatments.
intervention: furosemide
comparator: 0.9% saline
outcome: breathlessness, leg discomfort, chest tightness to exercise cessation were not significantly different across treatments.