evidence: In MSE Dose Group 1, the mean of maximum COWS score over the 24-hour period on BBUP was lower than on full μ-opioid agonist (4.6 vs 5.3), but the median maximum COWS scores were identical (4.0).
intervention: Buccal buprenorphine (BBUP)
comparator: Full μ-opioid agonist*
outcome: median maximum COWS scores