Th1 and Th1/Th2 of observation group was increased significantly comparing with that of control group, while Th2 decreased, the difference was statistically significant (P<0.05) (Table I and Fig. 1).
HBD-3 (standard, 10 μg:50 μg:1 mg, Art no., CSB-P12186-3; Beijing Biodee Biotechnology Co., Ltd., Beijing, China) of 10 ml once a day, for 7 days.
injected with placebo saline solution in the articular cavity
IL-2 and TNF-α