The scores of VAS for dyspnea, cough and quality of life and also respiratory rate, heart rate, and night time awaking due to dyspnea and night time awaking due to cough improved significantly after morphine nebulization without any major adverse events.
1 mg morphine sulfate diluted by 4 cc normal saline 0.5% using nebulizer once daily for 5 days
normal saline as placebo
Score: quality of life - COPD patients due to exposure to sulfur mustard (SM) and refractory to conventional therapies