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not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic 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severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe toxic not severe 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